--- /dev/null
+Basic Installation
+==================
+
+To build and install HTSlib, 'cd' to the htslib-1.x directory containing
+the package's source and type the following commands:
+
+ ./configure
+ make
+ make install
+
+The './configure' command checks your build environment and allows various
+optional functionality to be enabled (see Configuration below). If you
+don't want to select any optional functionality, you may wish to omit
+configure and just type 'make; make install' as for previous versions
+of HTSlib. However if the build fails you should run './configure' as
+it can diagnose the common reasons for build failures.
+
+The 'make' command builds the HTSlib library and and various useful
+utilities: bgzip, htsfile, and tabix. If compilation fails you should
+run './configure' as it can diagnose problems with your build environment
+that cause build failures.
+
+The 'make install' command installs the libraries, library header files,
+utilities, several manual pages, and a pkgconfig file to /usr/local.
+The installation location can be changed by configuring with --prefix=DIR
+or via 'make prefix=DIR install' (see Installation Locations below).
+
+
+Configuration
+=============
+
+By default, './configure' examines your build environment, checking for
+requirements such as the zlib development files, and arranges for a plain
+HTSlib build. The following configure options can be used to enable
+various features and specify further optional external requirements:
+
+--enable-plugins
+ Use plugins to implement exotic file access protocols and other
+ specialised facilities. This enables such facilities to be developed
+ and packaged outwith HTSlib, and somewhat isolates HTSlib-using programs
+ from their library dependencies. By default, any enabled pluggable
+ facilities (such as iRODS and libcurl file access) are built directly
+ within HTSlib.
+
+--with-plugin-dir=DIR
+ Specifies the directory into which plugins built while building HTSlib
+ should be installed; by default, LIBEXECDIR/htslib.
+
+--with-plugin-path=DIR:DIR:DIR...
+ Specifies the list of directories that HTSlib will search for plugins.
+ By default, only the directory specified via --with-plugin-dir will be
+ searched; you can use --with-plugin-path='DIR:$(plugindir):DIR' and so
+ on to cause additional directories to be searched.
+
+--with-irods[=DIR]
+ Specifies the location of the iRODS client library to use to enable
+ access to data objects stored in iRODS (<http://irods.org/>) via file
+ paths like 'irods:DATAOBJ'. DIR is the base of an iRODS source tree
+ such that the library is present as DIR/lib/core/obj/libRodsAPI.* and
+ headers are present under DIR/lib/api/include and so on. If '=DIR' is
+ omitted, $IRODS_HOME will be used as a base directory.
+
+--enable-libcurl
+ Use libcurl (<http://curl.haxx.se/>) to implement network access to
+ remote files via FTP, HTTP, HTTPS, S3, etc. By default, HTSlib uses
+ its own simple networking code to provide access via FTP and HTTP only.
+
+The configure script also accepts the usual options and environment variables
+for tuning installation locations and compilers: type './configure --help'
+for details. For example,
+
+ ./configure CC=icc --prefix=/opt/icc-compiled
+
+would specify that HTSlib is to be built with icc and installed into bin,
+lib, etc subdirectories under /opt/icc-compiled.
+
+
+Installation Locations
+======================
+
+By default, 'make install' installs HTSlib libraries under /usr/local/lib,
+HTSlib header files under /usr/local/include, utility programs under
+/usr/local/bin, etc. (To be precise, the header files are installed within
+a fixed 'htslib' subdirectory under the specified .../include location.)
+
+You can specify a different location to install HTSlib by configuring
+with --prefix=DIR or specify locations for particular parts of HTSlib by
+configuring with --libdir=DIR and so on. Type './configure --help' for
+the full list of such install directory options.
+
+Alternatively you can specify different locations at install time by
+typing 'make prefix=DIR install' or 'make libdir=DIR install' and so on.
+Consult the list of prefix/exec_prefix/etc variables near the top of the
+Makefile for the full list of such variables that can be overridden.
+
+You can also specify a staging area by typing 'make DESTDIR=DIR install',
+possibly in conjunction with other --prefix or prefix=DIR settings.
+For example,
+
+ make DESTDIR=/tmp/staging prefix=/opt
+
+would install into bin, lib, etc subdirectories under /tmp/staging/opt.
--- /dev/null
+[Files in this distribution outwith the cram/ subdirectory are distributed
+according to the terms of the following MIT/Expat license.]
+
+The MIT/Expat License
+
+Copyright (C) 2012-2014 Genome Research Ltd.
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE.
+
+
+[Files within the cram/ subdirectory in this distribution are distributed
+according to the terms of the following Modified 3-Clause BSD license.]
+
+The Modified-BSD License
+
+Copyright (C) 2012-2014 Genome Research Ltd.
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+1. Redistributions of source code must retain the above copyright notice,
+ this list of conditions and the following disclaimer.
+
+2. Redistributions in binary form must reproduce the above copyright notice,
+ this list of conditions and the following disclaimer in the documentation
+ and/or other materials provided with the distribution.
+
+3. Neither the names Genome Research Ltd and Wellcome Trust Sanger Institute
+ nor the names of its contributors may be used to endorse or promote products
+ derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS"
+AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
+IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR ITS CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+
+
+[The use of a range of years within a copyright notice in this distribution
+should be interpreted as being equivalent to a list of years including the
+first and last year specified and all consecutive years between them.
+
+For example, a copyright notice that reads "Copyright (C) 2005, 2007-2009,
+2011-2012" should be interpreted as being identical to a notice that reads
+"Copyright (C) 2005, 2007, 2008, 2009, 2011, 2012" and a copyright notice
+that reads "Copyright (C) 2005-2012" should be interpreted as being identical
+to a notice that reads "Copyright (C) 2005, 2006, 2007, 2008, 2009, 2010,
+2011, 2012".]
--- /dev/null
+# Makefile for htslib, a C library for high-throughput sequencing data formats.
+#
+# Copyright (C) 2013-2015 Genome Research Ltd.
+#
+# Author: John Marshall <jm18@sanger.ac.uk>
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in
+# all copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+# DEALINGS IN THE SOFTWARE.
+
+CC = gcc
+AR = ar
+RANLIB = ranlib
+
+CPPFLAGS =
+# TODO: probably update cram code to make it compile cleanly with -Wc++-compat
+CFLAGS = -g -Wall -O2
+EXTRA_CFLAGS_PIC = -fpic
+LDFLAGS =
+LIBS =
+
+# For now these don't work too well as samtools also needs to know to
+# add -lbz2 and -llzma if linking against the static libhts.a library.
+# TODO This needs configury and adding to htslib.pc.in.
+#
+# # Bzip2 support; optionally used by CRAM.
+# HAVE_LIBBZ2 := $(shell echo -e "\#include <bzlib.h>\012int main(void){return 0;}" > .test.c && $(CC) $(CFLAGS) $(CPPFLAGS) -o .test .test.c -lbz2 2>/dev/null && echo yes)
+# ifeq "$(HAVE_LIBBZ2)" "yes"
+# CPPFLAGS += -DHAVE_LIBBZ2
+# LIBS += -lbz2
+# endif
+#
+# # Lzma support; optionally used by CRAM.
+# HAVE_LIBLZMA := $(shell echo -e "\#include <lzma.h>\012int main(void){return 0;}" > .test.c && $(CC) $(CFLAGS) $(CPPFLAGS) -o .test .test.c -llzma 2>/dev/null && echo yes)
+# ifeq "$(HAVE_LIBLZMA)" "yes"
+# CPPFLAGS += -DHAVE_LIBLZMA
+# LIBS += -llzma
+# endif
+
+prefix = /usr/local
+exec_prefix = $(prefix)
+bindir = $(exec_prefix)/bin
+includedir = $(prefix)/include
+libdir = $(exec_prefix)/lib
+libexecdir = $(exec_prefix)/libexec
+datarootdir = $(prefix)/share
+mandir = $(datarootdir)/man
+man1dir = $(mandir)/man1
+man5dir = $(mandir)/man5
+pkgconfigdir= $(libdir)/pkgconfig
+
+MKDIR_P = mkdir -p
+INSTALL = install -p
+INSTALL_PROGRAM = $(INSTALL)
+INSTALL_DATA = $(INSTALL) -m 644
+INSTALL_DIR = $(MKDIR_P) -m 755
+
+# Set by config.mk if plugins are enabled
+plugindir =
+
+BUILT_PROGRAMS = \
+ bgzip \
+ htsfile \
+ tabix
+
+BUILT_TEST_PROGRAMS = \
+ test/fieldarith \
+ test/hfile \
+ test/sam \
+ test/test-regidx \
+ test/test_view \
+ test/test-vcf-api \
+ test/test-vcf-sweep
+
+all: lib-static lib-shared $(BUILT_PROGRAMS) plugins $(BUILT_TEST_PROGRAMS)
+
+HTSPREFIX =
+include htslib_vars.mk
+
+
+PACKAGE_VERSION = 1.3.1
+LIBHTS_SOVERSION = 1
+
+
+# $(NUMERIC_VERSION) is for items that must have a numeric X.Y.Z string
+# even if this is a dirty or untagged Git working tree.
+NUMERIC_VERSION = $(PACKAGE_VERSION)
+
+# If building from a Git repository, replace $(PACKAGE_VERSION) with the Git
+# description of the working tree: either a release tag with the same value
+# as $(PACKAGE_VERSION) above, or an exact description likely based on a tag.
+# Much of this is also GNU Make-specific. If you don't have GNU Make and/or
+# are not building from a Git repository, comment out this conditional.
+ifneq "$(wildcard .git)" ""
+original_version := $(PACKAGE_VERSION)
+PACKAGE_VERSION := $(shell git describe --always --dirty)
+
+# Unless the Git description matches /\d*\.\d*(\.\d*)?/, i.e., is exactly a tag
+# with a numeric name, revert $(NUMERIC_VERSION) to the original version number
+# written above, but with the patchlevel field bumped to 255.
+ifneq "$(subst ..,.,$(subst 0,,$(subst 1,,$(subst 2,,$(subst 3,,$(subst 4,,$(subst 5,,$(subst 6,,$(subst 7,,$(subst 8,,$(subst 9,,$(PACKAGE_VERSION))))))))))))" "."
+empty :=
+NUMERIC_VERSION := $(subst $(empty) ,.,$(wordlist 1,2,$(subst ., ,$(original_version))) 255)
+endif
+
+# Force version.h to be remade if $(PACKAGE_VERSION) has changed.
+version.h: $(if $(wildcard version.h),$(if $(findstring "$(PACKAGE_VERSION)",$(shell cat version.h)),,force))
+endif
+
+version.h:
+ echo '#define HTS_VERSION "$(PACKAGE_VERSION)"' > $@
+
+print-version:
+ @echo $(PACKAGE_VERSION)
+
+
+.SUFFIXES: .bundle .c .o .pico .so
+
+.c.o:
+ $(CC) $(CFLAGS) -I. $(CPPFLAGS) -c -o $@ $<
+
+.c.pico:
+ $(CC) $(CFLAGS) -I. $(CPPFLAGS) $(EXTRA_CFLAGS_PIC) -c -o $@ $<
+
+
+LIBHTS_OBJS = \
+ kfunc.o \
+ knetfile.o \
+ kstring.o \
+ bgzf.o \
+ faidx.o \
+ hfile.o \
+ hfile_net.o \
+ hts.o \
+ md5.o \
+ regidx.o \
+ sam.o \
+ synced_bcf_reader.o \
+ vcf_sweep.o \
+ tbx.o \
+ vcf.o \
+ vcfutils.o \
+ cram/cram_codecs.o \
+ cram/cram_decode.o \
+ cram/cram_encode.o \
+ cram/cram_external.o \
+ cram/cram_index.o \
+ cram/cram_io.o \
+ cram/cram_samtools.o \
+ cram/cram_stats.o \
+ cram/files.o \
+ cram/mFILE.o \
+ cram/open_trace_file.o \
+ cram/pooled_alloc.o \
+ cram/rANS_static.o \
+ cram/sam_header.o \
+ cram/string_alloc.o \
+ cram/thread_pool.o \
+ cram/vlen.o \
+ cram/zfio.o
+
+PLUGIN_OBJS =
+
+cram_h = cram/cram.h $(cram_samtools_h) $(cram_sam_header_h) $(cram_structs_h) $(cram_io_h) cram/cram_encode.h cram/cram_decode.h cram/cram_stats.h cram/cram_codecs.h cram/cram_index.h $(htslib_cram_h)
+cram_io_h = cram/cram_io.h $(cram_misc_h)
+cram_misc_h = cram/misc.h cram/os.h
+cram_sam_header_h = cram/sam_header.h cram/string_alloc.h cram/pooled_alloc.h $(htslib_khash_h) $(htslib_kstring_h)
+cram_samtools_h = cram/cram_samtools.h $(htslib_sam_h) $(cram_sam_header_h)
+cram_structs_h = cram/cram_structs.h cram/thread_pool.h cram/string_alloc.h $(htslib_khash_h)
+cram_open_trace_file_h = cram/open_trace_file.h cram/mFILE.h
+hfile_internal_h = hfile_internal.h $(htslib_hfile_h)
+hts_internal_h = hts_internal.h $(htslib_hts_h)
+
+
+# To be effective, config.mk needs to appear after most Makefile variables are
+# set but before most rules appear, so that it can both use previously-set
+# variables in its own rules' prerequisites and also update variables for use
+# in later rules' prerequisites.
+
+# If your make doesn't accept -include, change this to 'include' if you are
+# using the configure script or just comment the line out if you are not.
+-include config.mk
+
+# Usually config.h is generated by running configure or config.status,
+# but if those aren't used create a default config.h here.
+config.h:
+ echo '/* Empty config.h generated by Makefile */' > $@
+
+
+lib-static: libhts.a
+
+# $(shell), :=, and ifeq/.../endif are GNU Make-specific. If you don't have
+# GNU Make, comment out the parts of this conditional that don't apply.
+PLATFORM := $(shell uname -s)
+ifeq "$(PLATFORM)" "Darwin"
+SHLIB_FLAVOUR = dylib
+lib-shared: libhts.dylib
+BUILT_PLUGINS = $(PLUGIN_OBJS:.o=.bundle)
+else
+SHLIB_FLAVOUR = so
+lib-shared: libhts.so
+BUILT_PLUGINS = $(PLUGIN_OBJS:.o=.so)
+endif
+
+plugins: $(BUILT_PLUGINS)
+
+
+libhts.a: $(LIBHTS_OBJS)
+ @-rm -f $@
+ $(AR) -rc $@ $(LIBHTS_OBJS)
+ -$(RANLIB) $@
+
+
+# The target here is libhts.so, as that is the built file that other rules
+# depend upon and that is used when -lhts appears in other program's recipes.
+# As a byproduct invisible to make, libhts.so.NN is also created, as it is the
+# file used at runtime (when $LD_LIBRARY_PATH includes the build directory).
+
+libhts.so: $(LIBHTS_OBJS:.o=.pico)
+ $(CC) -shared -Wl,-soname,libhts.so.$(LIBHTS_SOVERSION) -pthread $(LDFLAGS) -o $@ $(LIBHTS_OBJS:.o=.pico) -lz -lm $(LIBS)
+ ln -sf $@ libhts.so.$(LIBHTS_SOVERSION)
+
+# Similarly this also creates libhts.NN.dylib as a byproduct, so that programs
+# when run can find this uninstalled shared library (when $DYLD_LIBRARY_PATH
+# includes this project's build directory).
+
+libhts.dylib: $(LIBHTS_OBJS)
+ $(CC) -dynamiclib -install_name $(libdir)/libhts.$(LIBHTS_SOVERSION).dylib -current_version $(NUMERIC_VERSION) -compatibility_version $(LIBHTS_SOVERSION) $(LDFLAGS) -o $@ $(LIBHTS_OBJS) -lz $(LIBS)
+ ln -sf $@ libhts.$(LIBHTS_SOVERSION).dylib
+
+
+.pico.so:
+ $(CC) -shared -Wl,-E -pthread $(LDFLAGS) -o $@ $< $(LIBS)
+
+.o.bundle:
+ $(CC) -bundle -Wl,-undefined,dynamic_lookup $(LDFLAGS) -o $@ $< $(LIBS)
+
+
+bgzf.o bgzf.pico: bgzf.c config.h $(htslib_hts_h) $(htslib_bgzf_h) $(htslib_hfile_h) $(htslib_khash_h)
+kstring.o kstring.pico: kstring.c config.h $(htslib_kstring_h)
+knetfile.o knetfile.pico: knetfile.c config.h $(htslib_knetfile_h)
+hfile.o hfile.pico: hfile.c config.h $(htslib_hfile_h) $(hfile_internal_h) $(hts_internal_h) $(htslib_khash_h)
+hfile_irods.o hfile_irods.pico: hfile_irods.c config.h $(hfile_internal_h) $(htslib_hts_h) $(htslib_kstring_h)
+hfile_libcurl.o hfile_libcurl.pico: hfile_libcurl.c config.h $(hfile_internal_h) $(htslib_hts_h) $(htslib_kstring_h)
+hfile_net.o hfile_net.pico: hfile_net.c config.h $(hfile_internal_h) $(htslib_knetfile_h)
+hts.o hts.pico: hts.c config.h version.h $(htslib_hts_h) $(htslib_bgzf_h) $(cram_h) $(htslib_hfile_h) $(htslib_khash_h) $(htslib_kseq_h) $(htslib_ksort_h) $(hts_internal_h)
+vcf.o vcf.pico: vcf.c config.h $(htslib_vcf_h) $(htslib_bgzf_h) $(htslib_tbx_h) $(htslib_hfile_h) $(hts_internal_h) $(htslib_khash_h) $(htslib_kseq_h) $(htslib_kstring_h) $(htslib_khash_str2int_h)
+sam.o sam.pico: sam.c config.h $(htslib_sam_h) $(htslib_bgzf_h) $(cram_h) $(hts_internal_h) $(htslib_hfile_h) $(htslib_khash_h) $(htslib_kseq_h) $(htslib_kstring_h)
+tbx.o tbx.pico: tbx.c config.h $(htslib_tbx_h) $(htslib_bgzf_h) $(htslib_khash_h)
+faidx.o faidx.pico: faidx.c config.h $(htslib_bgzf_h) $(htslib_faidx_h) $(htslib_hfile_h) $(htslib_khash_h) $(htslib_kstring_h)
+synced_bcf_reader.o synced_bcf_reader.pico: synced_bcf_reader.c config.h $(htslib_synced_bcf_reader_h) $(htslib_kseq_h) $(htslib_khash_str2int_h) $(htslib_bgzf_h)
+vcf_sweep.o vcf_sweep.pico: vcf_sweep.c config.h $(htslib_vcf_sweep_h) $(htslib_bgzf_h)
+vcfutils.o vcfutils.pico: vcfutils.c config.h $(htslib_vcfutils_h) $(htslib_kbitset_h)
+kfunc.o kfunc.pico: kfunc.c config.h $(htslib_kfunc_h)
+regidx.o regidx.pico: regidx.c config.h $(htslib_hts_h) $(htslib_kstring_h) $(htslib_kseq_h) $(htslib_khash_str2int_h) $(htslib_regidx_h)
+md5.o md5.pico: md5.c config.h $(htslib_hts_h)
+plugin.o plugin.pico: plugin.c config.h $(hts_internal_h) $(htslib_kstring_h)
+
+cram/cram_codecs.o cram/cram_codecs.pico: cram/cram_codecs.c config.h $(cram_h)
+cram/cram_decode.o cram/cram_decode.pico: cram/cram_decode.c config.h $(cram_h) cram/os.h $(htslib_hts_h)
+cram/cram_encode.o cram/cram_encode.pico: cram/cram_encode.c config.h $(cram_h) cram/os.h $(htslib_hts_h)
+cram/cram_external.o cram/cram_external.pico: cram/cram_external.c config.h $(htslib_hfile_h) $(cram_h)
+cram/cram_index.o cram/cram_index.pico: cram/cram_index.c config.h $(htslib_hfile_h) $(cram_h) cram/os.h cram/zfio.h $(hts_internal_h)
+cram/cram_io.o cram/cram_io.pico: cram/cram_io.c config.h $(cram_h) cram/os.h $(htslib_hts_h) $(cram_open_trace_file_h) cram/rANS_static.h $(htslib_hfile_h) $(htslib_bgzf_h) $(htslib_faidx_h)
+cram/cram_samtools.o cram/cram_samtools.pico: cram/cram_samtools.c config.h $(cram_h) $(htslib_sam_h)
+cram/cram_stats.o cram/cram_stats.pico: cram/cram_stats.c config.h $(cram_h) cram/os.h
+cram/files.o cram/files.pico: cram/files.c config.h $(cram_misc_h)
+cram/mFILE.o cram/mFILE.pico: cram/mFILE.c config.h cram/os.h cram/mFILE.h cram/vlen.h
+cram/open_trace_file.o cram/open_trace_file.pico: cram/open_trace_file.c config.h cram/os.h $(cram_open_trace_file_h) $(cram_misc_h) $(htslib_hfile_h)
+cram/pooled_alloc.o cram/pooled_alloc.pico: cram/pooled_alloc.c config.h cram/pooled_alloc.h
+cram/rANS_static.o cram/rANS_static.pico: cram/rANS_static.c config.h cram/rANS_static.h cram/rANS_byte.h
+cram/sam_header.o cram/sam_header.pico: cram/sam_header.c config.h $(cram_sam_header_h) cram/string_alloc.h
+cram/string_alloc.o cram/string_alloc.pico: cram/string_alloc.c config.h cram/string_alloc.h
+cram/thread_pool.o cram/thread_pool.pico: cram/thread_pool.c config.h cram/thread_pool.h
+cram/vlen.o cram/vlen.pico: cram/vlen.c config.h cram/vlen.h cram/os.h
+cram/zfio.o cram/zfio.pico: cram/zfio.c config.h cram/os.h cram/zfio.h
+
+
+bgzip: bgzip.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ bgzip.o libhts.a -lz $(LIBS)
+
+htsfile: htsfile.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ htsfile.o libhts.a -lz $(LIBS)
+
+tabix: tabix.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ tabix.o libhts.a -lz $(LIBS)
+
+bgzip.o: bgzip.c config.h $(htslib_bgzf_h) $(htslib_hts_h)
+htsfile.o: htsfile.c config.h $(htslib_hfile_h) $(htslib_hts_h) $(htslib_sam_h) $(htslib_vcf_h)
+tabix.o: tabix.c config.h $(htslib_tbx_h) $(htslib_sam_h) $(htslib_vcf_h) $(htslib_kseq_h) $(htslib_bgzf_h) $(htslib_hts_h) $(htslib_regidx_h)
+
+
+# For tests that might use it, set $REF_PATH explicitly to use only reference
+# areas within the test suite (or set it to ':' to use no reference areas).
+check test: htsfile $(BUILT_TEST_PROGRAMS)
+ test/fieldarith test/fieldarith.sam
+ test/hfile
+ test/sam test/ce.fa test/faidx.fa
+ test/test-regidx
+ cd test && REF_PATH=: ./test.pl
+
+test/fieldarith: test/fieldarith.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ test/fieldarith.o libhts.a -lz $(LIBS)
+
+test/hfile: test/hfile.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ test/hfile.o libhts.a -lz $(LIBS)
+
+test/sam: test/sam.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ test/sam.o libhts.a -lz $(LIBS)
+
+test/test-regidx: test/test-regidx.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ test/test-regidx.o libhts.a -lz $(LIBS)
+
+test/test_view: test/test_view.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ test/test_view.o libhts.a -lz $(LIBS)
+
+test/test-vcf-api: test/test-vcf-api.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ test/test-vcf-api.o libhts.a -lz $(LIBS)
+
+test/test-vcf-sweep: test/test-vcf-sweep.o libhts.a
+ $(CC) -pthread $(LDFLAGS) -o $@ test/test-vcf-sweep.o libhts.a -lz $(LIBS)
+
+test/fieldarith.o: test/fieldarith.c config.h $(htslib_sam_h)
+test/hfile.o: test/hfile.c config.h $(htslib_hfile_h) $(htslib_hts_defs_h)
+test/sam.o: test/sam.c config.h $(htslib_hts_defs_h) $(htslib_sam_h) $(htslib_faidx_h) $(htslib_kstring_h)
+test/test-regidx.o: test/test-regidx.c config.h $(htslib_regidx_h)
+test/test_view.o: test/test_view.c config.h $(cram_h) $(htslib_sam_h)
+test/test-vcf-api.o: test/test-vcf-api.c config.h $(htslib_hts_h) $(htslib_vcf_h) $(htslib_kstring_h) $(htslib_kseq_h)
+test/test-vcf-sweep.o: test/test-vcf-sweep.c config.h $(htslib_vcf_sweep_h)
+
+
+install: libhts.a $(BUILT_PROGRAMS) $(BUILT_PLUGINS) installdirs install-$(SHLIB_FLAVOUR) install-pkgconfig
+ $(INSTALL_PROGRAM) $(BUILT_PROGRAMS) $(DESTDIR)$(bindir)
+ if test -n "$(BUILT_PLUGINS)"; then $(INSTALL_PROGRAM) $(BUILT_PLUGINS) $(DESTDIR)$(plugindir); fi
+ $(INSTALL_DATA) htslib/*.h $(DESTDIR)$(includedir)/htslib
+ $(INSTALL_DATA) libhts.a $(DESTDIR)$(libdir)/libhts.a
+ $(INSTALL_DATA) htsfile.1 tabix.1 $(DESTDIR)$(man1dir)
+ $(INSTALL_DATA) faidx.5 sam.5 vcf.5 $(DESTDIR)$(man5dir)
+
+installdirs:
+ $(INSTALL_DIR) $(DESTDIR)$(bindir) $(DESTDIR)$(includedir) $(DESTDIR)$(includedir)/htslib $(DESTDIR)$(libdir) $(DESTDIR)$(man1dir) $(DESTDIR)$(man5dir) $(DESTDIR)$(pkgconfigdir)
+ if test -n "$(plugindir)"; then $(INSTALL_DIR) $(DESTDIR)$(plugindir); fi
+
+# After installation, the real file in $(libdir) will be libhts.so.X.Y.Z,
+# with symlinks libhts.so (used via -lhts during linking of client programs)
+# and libhts.so.NN (used by client executables at runtime).
+
+install-so: libhts.so installdirs
+ $(INSTALL_DATA) libhts.so $(DESTDIR)$(libdir)/libhts.so.$(PACKAGE_VERSION)
+ ln -sf libhts.so.$(PACKAGE_VERSION) $(DESTDIR)$(libdir)/libhts.so
+ ln -sf libhts.so.$(PACKAGE_VERSION) $(DESTDIR)$(libdir)/libhts.so.$(LIBHTS_SOVERSION)
+
+install-dylib: libhts.dylib installdirs
+ $(INSTALL_PROGRAM) libhts.dylib $(DESTDIR)$(libdir)/libhts.$(PACKAGE_VERSION).dylib
+ ln -sf libhts.$(PACKAGE_VERSION).dylib $(DESTDIR)$(libdir)/libhts.dylib
+ ln -sf libhts.$(PACKAGE_VERSION).dylib $(DESTDIR)$(libdir)/libhts.$(LIBHTS_SOVERSION).dylib
+
+# Substitute these pseudo-autoconf variables only at install time
+# so that "make install prefix=/prefix/path" etc continue to work.
+install-pkgconfig: installdirs
+ sed -e 's#@includedir@#$(includedir)#g;s#@libdir@#$(libdir)#g;s#@PACKAGE_VERSION@#$(PACKAGE_VERSION)#g' htslib.pc.in > $(DESTDIR)$(pkgconfigdir)/htslib.pc
+ chmod 644 $(DESTDIR)$(pkgconfigdir)/htslib.pc
+
+# A pkg-config file (suitable for copying to $PKG_CONFIG_PATH) that provides
+# flags for building against the uninstalled library in this build directory.
+htslib-uninstalled.pc: htslib.pc.in
+ sed -e 's#@includedir@#'`pwd`'#g;s#@libdir@#'`pwd`'#g' htslib.pc.in > $@
+
+
+testclean:
+ -rm -f test/*.tmp test/*.tmp.*
+
+mostlyclean: testclean
+ -rm -f *.o *.pico cram/*.o cram/*.pico test/*.o test/*.dSYM version.h
+
+clean: mostlyclean clean-$(SHLIB_FLAVOUR)
+ -rm -f libhts.a $(BUILT_PROGRAMS) $(BUILT_PLUGINS) $(BUILT_TEST_PROGRAMS)
+
+distclean maintainer-clean: clean
+ -rm -f config.cache config.h config.log config.mk config.status
+ -rm -f TAGS *-uninstalled.pc
+
+clean-so:
+ -rm -f libhts.so libhts.so.*
+
+clean-dylib:
+ -rm -f libhts.dylib libhts.*.dylib
+
+
+tags TAGS:
+ ctags -f TAGS *.[ch] cram/*.[ch] htslib/*.h
+
+# We recommend libhts-using programs be built against a separate htslib
+# installation. However if you feel that you must bundle htslib source
+# code with your program, this hook enables Automake-style "make dist"
+# for this subdirectory. If you do bundle an htslib snapshot, please
+# add identifying information to $(PACKAGE_VERSION) as appropriate.
+# (The wildcards attempt to omit non-exported files (.git*, README.md,
+# etc) and other detritus that might be in the top-level directory.)
+distdir:
+ tar -c *.[ch15] [ILMNRcht]*[ELSbcekmnt] | (cd $(distdir) && tar -x)
+ +cd $(distdir) && $(MAKE) distclean
+
+force:
+
+
+.PHONY: all check clean distclean distdir force
+.PHONY: install install-pkgconfig installdirs lib-shared lib-static
+.PHONY: maintainer-clean mostlyclean plugins print-version tags test testclean
+.PHONY: clean-so install-so
+.PHONY: clean-dylib install-dylib
--- /dev/null
+Noteworthy changes in release 1.3.1 (22 April 2016)
+
+* Improved error checking and reporting, especially of I/O errors when
+ writing output files (#17, #315, PR #271, PR #317).
+
+* Build fixes for 32-bit systems; be sure to run configure to enable
+ large file support and access to 2GiB+ files.
+
+* Numerous VCF parsing fixes (#321, #322, #323, #324, #325; PR #370).
+ Particular thanks to Kostya Kortchinsky of the Google Security Team
+ for testing and numerous input parsing bug reports.
+
+* HTSlib now prints an informational message when initially creating a
+ CRAM reference cache in the default location under your $HOME directory.
+ (No message is printed if you are using $REF_CACHE to specify a location.)
+
+* Avoided rare race condition when caching downloaded CRAM reference sequence
+ files, by using distinctive names for temporary files (in addition to O_EXCL,
+ which has always been used). Occasional corruption would previously occur
+ when multiple tools were simultaneously caching the same reference sequences
+ on an NFS filesystem that did not support O_EXCL (PR #320).
+
+* Prevented race condition in file access plugin loading (PR #341).
+
+* Fixed mpileup memory leak, so no more "[bam_plp_destroy] memory leak [...]
+ Continue anyway" warning messages (#299).
+
+* Various minor CRAM fixes.
+
+* Fixed documentation problems #348 and #358.
+
+
+Noteworthy changes in release 1.3 (15 December 2015)
+
+* Files can now be accessed via HTTPS and Amazon S3 in addition to HTTP
+ and FTP, when HTSlib is configured to use libcurl for network file access
+ rather than the included basic knetfile networking.
+
+* HTSlib can be built to use remote access hFILE backends (such as iRODS
+ and libcurl) via a plugin mechanism. This allows other backends to be
+ easily added and facilitates building tools that use HTSlib, as they
+ don't need to be linked with the backends' various required libraries.
+
+* When writing CRAM output, sam_open() etc now default to writing CRAM v3.0
+ rather than v2.1.
+
+* fai_build() and samtools faidx now accept initial whitespace in ">"
+ headers (e.g., "> chr1 description" is taken to refer to "chr1").
+
+* tabix --only-header works again (was broken in 1.2.x; #249).
+
+* HTSlib's configure script and Makefile now fully support the standard
+ convention of allowing CC/CPPFLAGS/CFLAGS/LDFLAGS/LIBS to be overridden
+ as needed. Previously the Makefile listened to $(LDLIBS) instead; if you
+ were overriding that, you should now override LIBS rather than LDLIBS.
+
+* Fixed bugs #168, #172, #176, #197, #206, #225, #245, #265, #295, and #296.
+
+
+Noteworthy changes in release 1.2.1 (3 February 2015)
+
+* Reinstated hts_file_type() and FT_* macros, which were available until 1.1
+ but briefly removed in 1.2. This function is deprecated and will be removed
+ in a future release -- you should use hts_detect_format() etc instead
+
+
+Noteworthy changes in release 1.2 (2 February 2015)
+
+* HTSlib now has a configure script which checks your build environment
+ and allows for selection of optional extras. See INSTALL for details
+
+* By default, reference sequences are fetched from the EBI CRAM Reference
+ Registry and cached in your $HOME cache directory. This behaviour can
+ be controlled by setting REF_PATH and REF_CACHE enviroment variables
+ (see the samtools(1) man page for details)
+
+* Numerous CRAM improvements:
+ - Support for CRAM v3.0, an upcoming revision to CRAM supporting
+ better compression and per-container checksums
+ - EOF checking for v2.1 and v3.0 (similar to checking BAM EOF blocks)
+ - Non-standard values for PNEXT and TLEN fields are now preserved
+ - hts_set_fai_filename() now provides a reference file when encoding
+ - Generated read names are now numbered from 1, rather than being
+ labelled 'slice:record-in-slice'
+ - Multi-threading and speed improvements
+
+* New htsfile command for identifying file formats, and corresponding
+ file format detection APIs
+
+* New tabix --regions FILE, --targets FILE options for filtering via BED files
+
+* Optional iRODS file access, disabled by default. Configure with --with-irods
+ to enable accessing iRODS data objects directly via 'irods:DATAOBJ'
+
+* All occurences of 2^29 in the source have been eliminated, so indexing
+ and querying against reference sequences larger than 512Mbp works (when
+ using CSI indices)
+
+* Support for plain GZIP compression in various places
+
+* VCF header editing speed improvements
+
+* Added seq_nt16_int[] (equivalent to the samtools API's bam_nt16_nt4_table)
+
+* Reinstated faidx_fetch_nseq(), which was accidentally removed from 1.1.
+ Now faidx_fetch_nseq() and faidx_nseq() are equivalent; eventually
+ faidx_fetch_nseq() will be deprecated and removed [#156]
+
+* Fixed bugs #141, #152, #155, #158, #159, and various memory leaks
--- /dev/null
+HTSlib is an implementation of a unified C library for accessing common file
+formats, such as SAM, CRAM, VCF, and BCF, used for high-throughput sequencing
+data. It is the core library used by samtools and bcftools.
+
+See INSTALL for building and installation instructions.
--- /dev/null
+/* The MIT License
+
+ Copyright (c) 2008 Broad Institute / Massachusetts Institute of Technology
+ 2011, 2012 Attractive Chaos <attractor@live.co.uk>
+ Copyright (C) 2009, 2013-2016 Genome Research Ltd
+
+ Permission is hereby granted, free of charge, to any person obtaining a copy
+ of this software and associated documentation files (the "Software"), to deal
+ in the Software without restriction, including without limitation the rights
+ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+ copies of the Software, and to permit persons to whom the Software is
+ furnished to do so, subject to the following conditions:
+
+ The above copyright notice and this permission notice shall be included in
+ all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+ IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+ FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+ AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+ LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+ OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
+ THE SOFTWARE.
+*/
+
+#include <config.h>
+
+#include <stdio.h>
+#include <stdlib.h>
+#include <string.h>
+#include <errno.h>
+#include <unistd.h>
+#include <assert.h>
+#include <pthread.h>
+#include <sys/types.h>
+#include <inttypes.h>
+
+#include "htslib/hts.h"
+#include "htslib/bgzf.h"
+#include "htslib/hfile.h"
+
+#define BGZF_CACHE
+#define BGZF_MT
+
+#define BLOCK_HEADER_LENGTH 18
+#define BLOCK_FOOTER_LENGTH 8
+
+
+/* BGZF/GZIP header (speciallized from RFC 1952; little endian):
+ +---+---+---+---+---+---+---+---+---+---+---+---+---+---+---+---+---+---+
+ | 31|139| 8| 4| 0| 0|255| 6| 66| 67| 2|BLK_LEN|
+ +---+---+---+---+---+---+---+---+---+---+---+---+---+---+---+---+---+---+
+ BGZF extension:
+ ^ ^ ^ ^
+ | | | |
+ FLG.EXTRA XLEN B C
+
+ BGZF format is compatible with GZIP. It limits the size of each compressed
+ block to 2^16 bytes and adds and an extra "BC" field in the gzip header which
+ records the size.
+
+*/
+static const uint8_t g_magic[19] = "\037\213\010\4\0\0\0\0\0\377\6\0\102\103\2\0\0\0";
+
+#ifdef BGZF_CACHE
+typedef struct {
+ int size;
+ uint8_t *block;
+ int64_t end_offset;
+} cache_t;
+#include "htslib/khash.h"
+KHASH_MAP_INIT_INT64(cache, cache_t)
+#endif
+
+typedef struct
+{
+ uint64_t uaddr; // offset w.r.t. uncompressed data
+ uint64_t caddr; // offset w.r.t. compressed data
+}
+bgzidx1_t;
+
+struct __bgzidx_t
+{
+ int noffs, moffs; // the size of the index, n:used, m:allocated
+ bgzidx1_t *offs; // offsets
+ uint64_t ublock_addr; // offset of the current block (uncompressed data)
+};
+
+void bgzf_index_destroy(BGZF *fp);
+int bgzf_index_add_block(BGZF *fp);
+
+static inline void packInt16(uint8_t *buffer, uint16_t value)
+{
+ buffer[0] = value;
+ buffer[1] = value >> 8;
+}
+
+static inline int unpackInt16(const uint8_t *buffer)
+{
+ return buffer[0] | buffer[1] << 8;
+}
+
+static inline void packInt32(uint8_t *buffer, uint32_t value)
+{
+ buffer[0] = value;
+ buffer[1] = value >> 8;
+ buffer[2] = value >> 16;
+ buffer[3] = value >> 24;
+}
+
+static const char *bgzf_zerr(int errnum, z_stream *zs)
+{
+ static char buffer[32];
+
+ /* Return zs->msg if available.
+ zlib doesn't set this very reliably. Looking at the source suggests
+ that it may get set to a useful message for deflateInit2, inflateInit2
+ and inflate when it returns Z_DATA_ERROR. For inflate with other
+ return codes, deflate, deflateEnd and inflateEnd it doesn't appear
+ to be useful. For the likely non-useful cases, the caller should
+ pass NULL into zs. */
+
+ if (zs && zs->msg) return zs->msg;
+
+ // gzerror OF((gzFile file, int *errnum)
+ switch (errnum) {
+ case Z_ERRNO:
+ return strerror(errno);
+ case Z_STREAM_ERROR:
+ return "invalid parameter/compression level, or inconsistent stream state";
+ case Z_DATA_ERROR:
+ return "invalid or incomplete IO";
+ case Z_MEM_ERROR:
+ return "out of memory";
+ case Z_BUF_ERROR:
+ return "progress temporarily not possible, or in() / out() returned an error";
+ case Z_VERSION_ERROR:
+ return "zlib version mismatch";
+ case Z_OK: // 0: maybe gzgets error Z_NULL
+ default:
+ snprintf(buffer, sizeof(buffer), "[%d] unknown", errnum);
+ return buffer; // FIXME: Not thread-safe.
+ }
+}
+
+static BGZF *bgzf_read_init(hFILE *hfpr)
+{
+ BGZF *fp;
+ uint8_t magic[18];
+ ssize_t n = hpeek(hfpr, magic, 18);
+ if (n < 0) return NULL;
+
+ fp = (BGZF*)calloc(1, sizeof(BGZF));
+ if (fp == NULL) return NULL;
+
+ fp->is_write = 0;
+ fp->is_compressed = (n==2 && magic[0]==0x1f && magic[1]==0x8b);
+ fp->uncompressed_block = malloc(BGZF_MAX_BLOCK_SIZE);
+ fp->compressed_block = malloc(BGZF_MAX_BLOCK_SIZE);
+ fp->is_compressed = (n==18 && magic[0]==0x1f && magic[1]==0x8b) ? 1 : 0;
+ fp->is_gzip = ( !fp->is_compressed || ((magic[3]&4) && memcmp(&magic[12], "BC\2\0",4)==0) ) ? 0 : 1;
+#ifdef BGZF_CACHE
+ fp->cache = kh_init(cache);
+#endif
+ return fp;
+}
+
+// get the compress level from the mode string: compress_level==-1 for the default level, -2 plain uncompressed
+static int mode2level(const char *__restrict mode)
+{
+ int i, compress_level = -1;
+ for (i = 0; mode[i]; ++i)
+ if (mode[i] >= '0' && mode[i] <= '9') break;
+ if (mode[i]) compress_level = (int)mode[i] - '0';
+ if (strchr(mode, 'u')) compress_level = -2;
+ return compress_level;
+}
+static BGZF *bgzf_write_init(const char *mode)
+{
+ BGZF *fp;
+ fp = (BGZF*)calloc(1, sizeof(BGZF));
+ if (fp == NULL) goto mem_fail;
+ fp->is_write = 1;
+ int compress_level = mode2level(mode);
+ if ( compress_level==-2 )
+ {
+ fp->is_compressed = 0;
+ return fp;
+ }
+ fp->is_compressed = 1;
+
+ fp->uncompressed_block = malloc(BGZF_MAX_BLOCK_SIZE);
+ if (fp->uncompressed_block == NULL) goto mem_fail;
+ fp->compressed_block = malloc(BGZF_MAX_BLOCK_SIZE);
+ if (fp->compressed_block == NULL) goto mem_fail;
+
+ fp->compress_level = compress_level < 0? Z_DEFAULT_COMPRESSION : compress_level; // Z_DEFAULT_COMPRESSION==-1
+ if (fp->compress_level > 9) fp->compress_level = Z_DEFAULT_COMPRESSION;
+ if ( strchr(mode,'g') )
+ {
+ // gzip output
+ fp->is_gzip = 1;
+ fp->gz_stream = (z_stream*)calloc(1,sizeof(z_stream));
+ if (fp->gz_stream == NULL) goto mem_fail;
+ fp->gz_stream->zalloc = NULL;
+ fp->gz_stream->zfree = NULL;
+ fp->gz_stream->msg = NULL;
+
+ int ret = deflateInit2(fp->gz_stream, fp->compress_level, Z_DEFLATED, 15|16, 8, Z_DEFAULT_STRATEGY);
+ if (ret!=Z_OK) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] deflateInit2 failed: %s\n",
+ __func__, bgzf_zerr(ret, fp->gz_stream));
+ }
+ goto fail;
+ }
+ }
+ return fp;
+
+ mem_fail:
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] %s\n", __func__, strerror(errno));
+ }
+ fail:
+ if (fp != NULL) {
+ free(fp->uncompressed_block);
+ free(fp->compressed_block);
+ free(fp->gz_stream);
+ free(fp);
+ }
+ return NULL;
+}
+
+BGZF *bgzf_open(const char *path, const char *mode)
+{
+ BGZF *fp = 0;
+ assert(compressBound(BGZF_BLOCK_SIZE) < BGZF_MAX_BLOCK_SIZE);
+ if (strchr(mode, 'r')) {
+ hFILE *fpr;
+ if ((fpr = hopen(path, mode)) == 0) return 0;
+ fp = bgzf_read_init(fpr);
+ if (fp == 0) { hclose_abruptly(fpr); return NULL; }
+ fp->fp = fpr;
+ } else if (strchr(mode, 'w') || strchr(mode, 'a')) {
+ hFILE *fpw;
+ if ((fpw = hopen(path, mode)) == 0) return 0;
+ fp = bgzf_write_init(mode);
+ if (fp == NULL) return NULL;
+ fp->fp = fpw;
+ }
+ else { errno = EINVAL; return 0; }
+
+ fp->is_be = ed_is_big();
+ return fp;
+}
+
+BGZF *bgzf_dopen(int fd, const char *mode)
+{
+ BGZF *fp = 0;
+ assert(compressBound(BGZF_BLOCK_SIZE) < BGZF_MAX_BLOCK_SIZE);
+ if (strchr(mode, 'r')) {
+ hFILE *fpr;
+ if ((fpr = hdopen(fd, mode)) == 0) return 0;
+ fp = bgzf_read_init(fpr);
+ if (fp == 0) { hclose_abruptly(fpr); return NULL; } // FIXME this closes fd
+ fp->fp = fpr;
+ } else if (strchr(mode, 'w') || strchr(mode, 'a')) {
+ hFILE *fpw;
+ if ((fpw = hdopen(fd, mode)) == 0) return 0;
+ fp = bgzf_write_init(mode);
+ if (fp == NULL) return NULL;
+ fp->fp = fpw;
+ }
+ else { errno = EINVAL; return 0; }
+
+ fp->is_be = ed_is_big();
+ return fp;
+}
+
+BGZF *bgzf_hopen(hFILE *hfp, const char *mode)
+{
+ BGZF *fp = NULL;
+ assert(compressBound(BGZF_BLOCK_SIZE) < BGZF_MAX_BLOCK_SIZE);
+ if (strchr(mode, 'r')) {
+ fp = bgzf_read_init(hfp);
+ if (fp == NULL) return NULL;
+ } else if (strchr(mode, 'w') || strchr(mode, 'a')) {
+ fp = bgzf_write_init(mode);
+ if (fp == NULL) return NULL;
+ }
+ else { errno = EINVAL; return 0; }
+
+ fp->fp = hfp;
+ fp->is_be = ed_is_big();
+ return fp;
+}
+
+int bgzf_compress(void *_dst, size_t *dlen, const void *src, size_t slen, int level)
+{
+ uint32_t crc;
+ z_stream zs;
+ uint8_t *dst = (uint8_t*)_dst;
+
+ // compress the body
+ zs.zalloc = NULL; zs.zfree = NULL;
+ zs.msg = NULL;
+ zs.next_in = (Bytef*)src;
+ zs.avail_in = slen;
+ zs.next_out = dst + BLOCK_HEADER_LENGTH;
+ zs.avail_out = *dlen - BLOCK_HEADER_LENGTH - BLOCK_FOOTER_LENGTH;
+ int ret = deflateInit2(&zs, level, Z_DEFLATED, -15, 8, Z_DEFAULT_STRATEGY); // -15 to disable zlib header/footer
+ if (ret!=Z_OK) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] deflateInit2 failed: %s\n",
+ __func__, bgzf_zerr(ret, &zs));
+ }
+ return -1;
+ }
+ if ((ret = deflate(&zs, Z_FINISH)) != Z_STREAM_END) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] deflate failed: %s\n",
+ __func__, bgzf_zerr(ret, ret == Z_DATA_ERROR ? &zs : NULL));
+ }
+ return -1;
+ }
+ if ((ret = deflateEnd(&zs)) != Z_OK) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] deflateEnd failed: %s\n",
+ __func__, bgzf_zerr(ret, NULL));
+ }
+ return -1;
+ }
+ *dlen = zs.total_out + BLOCK_HEADER_LENGTH + BLOCK_FOOTER_LENGTH;
+ // write the header
+ memcpy(dst, g_magic, BLOCK_HEADER_LENGTH); // the last two bytes are a place holder for the length of the block
+ packInt16(&dst[16], *dlen - 1); // write the compressed length; -1 to fit 2 bytes
+ // write the footer
+ crc = crc32(crc32(0L, NULL, 0L), (Bytef*)src, slen);
+ packInt32((uint8_t*)&dst[*dlen - 8], crc);
+ packInt32((uint8_t*)&dst[*dlen - 4], slen);
+ return 0;
+}
+
+static int bgzf_gzip_compress(BGZF *fp, void *_dst, size_t *dlen, const void *src, size_t slen, int level)
+{
+ uint8_t *dst = (uint8_t*)_dst;
+ z_stream *zs = fp->gz_stream;
+ int flush = slen ? Z_NO_FLUSH : Z_FINISH;
+ zs->next_in = (Bytef*)src;
+ zs->avail_in = slen;
+ zs->next_out = dst;
+ zs->avail_out = *dlen;
+ int ret = deflate(zs, flush);
+ if (ret == Z_STREAM_ERROR) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] deflate failed: %s\n",
+ __func__, bgzf_zerr(ret, NULL));
+ }
+ return -1;
+ }
+ *dlen = *dlen - zs->avail_out;
+ return 0;
+}
+
+// Deflate the block in fp->uncompressed_block into fp->compressed_block. Also adds an extra field that stores the compressed block length.
+static int deflate_block(BGZF *fp, int block_length)
+{
+ size_t comp_size = BGZF_MAX_BLOCK_SIZE;
+ int ret;
+ if ( !fp->is_gzip )
+ ret = bgzf_compress(fp->compressed_block, &comp_size, fp->uncompressed_block, block_length, fp->compress_level);
+ else
+ ret = bgzf_gzip_compress(fp, fp->compressed_block, &comp_size, fp->uncompressed_block, block_length, fp->compress_level);
+
+ if ( ret != 0 )
+ {
+ if (hts_verbose >= 3) {
+ fprintf(stderr, "[E::%s] compression error %d\n", __func__, ret);
+ }
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ fp->block_offset = 0;
+ return comp_size;
+}
+
+// Inflate the block in fp->compressed_block into fp->uncompressed_block
+static int inflate_block(BGZF* fp, int block_length)
+{
+ z_stream zs;
+ zs.zalloc = NULL;
+ zs.zfree = NULL;
+ zs.msg = NULL;
+ zs.next_in = (Bytef*)fp->compressed_block + 18;
+ zs.avail_in = block_length - 16;
+ zs.next_out = (Bytef*)fp->uncompressed_block;
+ zs.avail_out = BGZF_MAX_BLOCK_SIZE;
+
+ int ret = inflateInit2(&zs, -15);
+ if (ret != Z_OK) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] inflateInit2 failed: %s\n",
+ __func__, bgzf_zerr(ret, &zs));
+ }
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ if ((ret = inflate(&zs, Z_FINISH)) != Z_STREAM_END) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] inflate failed: %s\n",
+ __func__, bgzf_zerr(ret, ret == Z_DATA_ERROR ? &zs : NULL));
+ }
+ if ((ret = inflateEnd(&zs)) != Z_OK) {
+ if (hts_verbose >= 2) {
+ fprintf(stderr, "[E::%s] inflateEnd failed: %s\n",
+ __func__, bgzf_zerr(ret, NULL));
+ }
+ }
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ if ((ret = inflateEnd(&zs)) != Z_OK) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] inflateEnd failed: %s\n",
+ __func__, bgzf_zerr(ret, NULL));
+ }
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ return zs.total_out;
+}
+
+static int inflate_gzip_block(BGZF *fp, int cached)
+{
+ int ret = Z_OK;
+ do
+ {
+ if ( !cached && fp->gz_stream->avail_out!=0 )
+ {
+ fp->gz_stream->avail_in = hread(fp->fp, fp->compressed_block, BGZF_BLOCK_SIZE);
+ if ( fp->gz_stream->avail_in<=0 ) return fp->gz_stream->avail_in;
+ if ( fp->gz_stream->avail_in==0 ) break;
+ fp->gz_stream->next_in = fp->compressed_block;
+ }
+ else cached = 0;
+ do
+ {
+ fp->gz_stream->next_out = (Bytef*)fp->uncompressed_block + fp->block_offset;
+ fp->gz_stream->avail_out = BGZF_MAX_BLOCK_SIZE - fp->block_offset;
+ fp->gz_stream->msg = NULL;
+ ret = inflate(fp->gz_stream, Z_NO_FLUSH);
+ if ( ret==Z_BUF_ERROR ) continue; // non-critical error
+ if ( ret<0 ) {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] inflate failed: %s\n",
+ __func__,
+ bgzf_zerr(ret, ret == Z_DATA_ERROR ? fp->gz_stream : NULL));
+ }
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ unsigned int have = BGZF_MAX_BLOCK_SIZE - fp->gz_stream->avail_out;
+ if ( have ) return have;
+ }
+ while ( fp->gz_stream->avail_out == 0 );
+ }
+ while (ret != Z_STREAM_END);
+ return BGZF_MAX_BLOCK_SIZE - fp->gz_stream->avail_out;
+}
+
+// Returns: 0 on success (BGZF header); -1 on non-BGZF GZIP header; -2 on error
+static int check_header(const uint8_t *header)
+{
+ if ( header[0] != 31 || header[1] != 139 || header[2] != 8 ) return -2;
+ return ((header[3] & 4) != 0
+ && unpackInt16((uint8_t*)&header[10]) == 6
+ && header[12] == 'B' && header[13] == 'C'
+ && unpackInt16((uint8_t*)&header[14]) == 2) ? 0 : -1;
+}
+
+#ifdef BGZF_CACHE
+static void free_cache(BGZF *fp)
+{
+ khint_t k;
+ khash_t(cache) *h = (khash_t(cache)*)fp->cache;
+ if (fp->is_write) return;
+ for (k = kh_begin(h); k < kh_end(h); ++k)
+ if (kh_exist(h, k)) free(kh_val(h, k).block);
+ kh_destroy(cache, h);
+}
+
+static int load_block_from_cache(BGZF *fp, int64_t block_address)
+{
+ khint_t k;
+ cache_t *p;
+ khash_t(cache) *h = (khash_t(cache)*)fp->cache;
+ k = kh_get(cache, h, block_address);
+ if (k == kh_end(h)) return 0;
+ p = &kh_val(h, k);
+ if (fp->block_length != 0) fp->block_offset = 0;
+ fp->block_address = block_address;
+ fp->block_length = p->size;
+ memcpy(fp->uncompressed_block, p->block, BGZF_MAX_BLOCK_SIZE);
+ if ( hseek(fp->fp, p->end_offset, SEEK_SET) < 0 )
+ {
+ // todo: move the error up
+ fprintf(stderr,"Could not hseek to %"PRId64"\n", p->end_offset);
+ exit(1);
+ }
+ return p->size;
+}
+
+static void cache_block(BGZF *fp, int size)
+{
+ int ret;
+ khint_t k;
+ cache_t *p;
+ khash_t(cache) *h = (khash_t(cache)*)fp->cache;
+ if (BGZF_MAX_BLOCK_SIZE >= fp->cache_size) return;
+ if ((kh_size(h) + 1) * BGZF_MAX_BLOCK_SIZE > (uint32_t)fp->cache_size) {
+ /* A better way would be to remove the oldest block in the
+ * cache, but here we remove a random one for simplicity. This
+ * should not have a big impact on performance. */
+ for (k = kh_begin(h); k < kh_end(h); ++k)
+ if (kh_exist(h, k)) break;
+ if (k < kh_end(h)) {
+ free(kh_val(h, k).block);
+ kh_del(cache, h, k);
+ }
+ }
+ k = kh_put(cache, h, fp->block_address, &ret);
+ if (ret == 0) return; // if this happens, a bug!
+ p = &kh_val(h, k);
+ p->size = fp->block_length;
+ p->end_offset = fp->block_address + size;
+ p->block = (uint8_t*)malloc(BGZF_MAX_BLOCK_SIZE);
+ memcpy(kh_val(h, k).block, fp->uncompressed_block, BGZF_MAX_BLOCK_SIZE);
+}
+#else
+static void free_cache(BGZF *fp) {}
+static int load_block_from_cache(BGZF *fp, int64_t block_address) {return 0;}
+static void cache_block(BGZF *fp, int size) {}
+#endif
+
+int bgzf_read_block(BGZF *fp)
+{
+ uint8_t header[BLOCK_HEADER_LENGTH], *compressed_block;
+ int count, size = 0, block_length, remaining;
+
+ // Reading an uncompressed file
+ if ( !fp->is_compressed )
+ {
+ count = hread(fp->fp, fp->uncompressed_block, BGZF_MAX_BLOCK_SIZE);
+ if (count < 0) // Error
+ {
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+ else if (count == 0) // EOF
+ {
+ fp->block_length = 0;
+ return 0;
+ }
+ if (fp->block_length != 0) fp->block_offset = 0;
+ fp->block_address += count;
+ fp->block_length = count;
+ return 0;
+ }
+
+ // Reading compressed file
+ int64_t block_address;
+ block_address = htell(fp->fp);
+ if ( fp->is_gzip && fp->gz_stream ) // is this is a initialized gzip stream?
+ {
+ count = inflate_gzip_block(fp, 0);
+ if ( count<0 )
+ {
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ fp->block_length = count;
+ fp->block_address = block_address;
+ return 0;
+ }
+ if (fp->cache_size && load_block_from_cache(fp, block_address)) return 0;
+ count = hread(fp->fp, header, sizeof(header));
+ if (count == 0) { // no data read
+ fp->block_length = 0;
+ return 0;
+ }
+ int ret;
+ if ( count != sizeof(header) || (ret=check_header(header))==-2 )
+ {
+ fp->errcode |= BGZF_ERR_HEADER;
+ return -1;
+ }
+ if ( ret==-1 )
+ {
+ // GZIP, not BGZF
+ uint8_t *cblock = (uint8_t*)fp->compressed_block;
+ memcpy(cblock, header, sizeof(header));
+ count = hread(fp->fp, cblock+sizeof(header), BGZF_BLOCK_SIZE - sizeof(header)) + sizeof(header);
+ int nskip = 10;
+
+ // Check optional fields to skip: FLG.FNAME,FLG.FCOMMENT,FLG.FHCRC,FLG.FEXTRA
+ // Note: Some of these fields are untested, I did not have appropriate data available
+ if ( header[3] & 0x4 ) // FLG.FEXTRA
+ {
+ nskip += unpackInt16(&cblock[nskip]) + 2;
+ }
+ if ( header[3] & 0x8 ) // FLG.FNAME
+ {
+ while ( nskip<count && cblock[nskip] ) nskip++;
+ nskip++;
+ }
+ if ( header[3] & 0x10 ) // FLG.FCOMMENT
+ {
+ while ( nskip<count && cblock[nskip] ) nskip++;
+ nskip++;
+ }
+ if ( header[3] & 0x2 ) nskip += 2; // FLG.FHCRC
+
+ /* FIXME: Should handle this better. There's no reason why
+ someone shouldn't include a massively long comment in their
+ gzip stream. */
+ if ( nskip >= count )
+ {
+ fp->errcode |= BGZF_ERR_HEADER;
+ return -1;
+ }
+
+ fp->is_gzip = 1;
+ fp->gz_stream = (z_stream*) calloc(1,sizeof(z_stream));
+ int ret = inflateInit2(fp->gz_stream, -15);
+ if (ret != Z_OK)
+ {
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] inflateInit2 failed: %s",
+ __func__, bgzf_zerr(ret, fp->gz_stream));
+ }
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ fp->gz_stream->avail_in = count - nskip;
+ fp->gz_stream->next_in = cblock + nskip;
+ count = inflate_gzip_block(fp, 1);
+ if ( count<0 )
+ {
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ fp->block_length = count;
+ fp->block_address = block_address;
+ if ( fp->idx_build_otf ) return -1; // cannot build index for gzip
+ return 0;
+ }
+ size = count;
+ block_length = unpackInt16((uint8_t*)&header[16]) + 1; // +1 because when writing this number, we used "-1"
+ compressed_block = (uint8_t*)fp->compressed_block;
+ memcpy(compressed_block, header, BLOCK_HEADER_LENGTH);
+ remaining = block_length - BLOCK_HEADER_LENGTH;
+ count = hread(fp->fp, &compressed_block[BLOCK_HEADER_LENGTH], remaining);
+ if (count != remaining) {
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+ size += count;
+ if ((count = inflate_block(fp, block_length)) < 0) {
+ if (hts_verbose >= 2) fprintf(stderr, "[E::%s] inflate_block error %d\n", __func__, count);
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ if (fp->block_length != 0) fp->block_offset = 0; // Do not reset offset if this read follows a seek.
+ fp->block_address = block_address;
+ fp->block_length = count;
+ if ( fp->idx_build_otf )
+ {
+ bgzf_index_add_block(fp);
+ fp->idx->ublock_addr += count;
+ }
+ cache_block(fp, size);
+ return 0;
+}
+
+ssize_t bgzf_read(BGZF *fp, void *data, size_t length)
+{
+ ssize_t bytes_read = 0;
+ uint8_t *output = (uint8_t*)data;
+ if (length <= 0) return 0;
+ assert(fp->is_write == 0);
+ while (bytes_read < length) {
+ int copy_length, available = fp->block_length - fp->block_offset;
+ uint8_t *buffer;
+ if (available <= 0) {
+ int ret = bgzf_read_block(fp);
+ if (ret != 0) {
+ if (hts_verbose >= 2) {
+ fprintf(stderr, "[E::%s] bgzf_read_block error %d after %zd of %zu bytes\n", __func__, ret, bytes_read, length);
+ }
+ fp->errcode |= BGZF_ERR_ZLIB;
+ return -1;
+ }
+ available = fp->block_length - fp->block_offset;
+ if (available <= 0) break;
+ }
+ copy_length = length - bytes_read < available? length - bytes_read : available;
+ buffer = (uint8_t*)fp->uncompressed_block;
+ memcpy(output, buffer + fp->block_offset, copy_length);
+ fp->block_offset += copy_length;
+ output += copy_length;
+ bytes_read += copy_length;
+ }
+ if (fp->block_offset == fp->block_length) {
+ fp->block_address = htell(fp->fp);
+ fp->block_offset = fp->block_length = 0;
+ }
+ fp->uncompressed_address += bytes_read;
+ return bytes_read;
+}
+
+ssize_t bgzf_raw_read(BGZF *fp, void *data, size_t length)
+{
+ return hread(fp->fp, data, length);
+}
+
+#ifdef BGZF_MT
+
+typedef struct {
+ struct bgzf_mtaux_t *mt;
+ void *buf;
+ int i, errcode, toproc, compress_level;
+} worker_t;
+
+typedef struct bgzf_mtaux_t {
+ int n_threads, n_blks, curr, done;
+ volatile int proc_cnt;
+ void **blk;
+ int *len;
+ worker_t *w;
+ pthread_t *tid;
+ pthread_mutex_t lock;
+ pthread_cond_t cv;
+} mtaux_t;
+
+static int worker_aux(worker_t *w)
+{
+ int i, stop = 0;
+ // wait for condition: to process or all done
+ pthread_mutex_lock(&w->mt->lock);
+ while (!w->toproc && !w->mt->done)
+ pthread_cond_wait(&w->mt->cv, &w->mt->lock);
+ if (w->mt->done) stop = 1;
+ w->toproc = 0;
+ pthread_mutex_unlock(&w->mt->lock);
+ if (stop) return 1; // to quit the thread
+ w->errcode = 0;
+ for (i = w->i; i < w->mt->curr; i += w->mt->n_threads) {
+ size_t clen = BGZF_MAX_BLOCK_SIZE;
+ int ret = bgzf_compress(w->buf, &clen, w->mt->blk[i], w->mt->len[i], w->compress_level);
+ if (ret != 0) {
+ if (hts_verbose >= 2) fprintf(stderr, "[E::%s] bgzf_compress error %d\n", __func__, ret);
+ w->errcode |= BGZF_ERR_ZLIB; // Report error
+ // We're not going to do any more, so set remaining lengths to 0
+ for (; i < w->mt->curr; i += w->mt->n_threads) w->mt->len[i] = 0;
+ break; // Give up
+ } else {
+ memcpy(w->mt->blk[i], w->buf, clen);
+ w->mt->len[i] = clen;
+ }
+ }
+ __sync_fetch_and_add(&w->mt->proc_cnt, 1);
+ return 0;
+}
+
+static void *mt_worker(void *data)
+{
+ while (worker_aux((worker_t*)data) == 0);
+ return 0;
+}
+
+int bgzf_mt(BGZF *fp, int n_threads, int n_sub_blks)
+{
+ int i;
+ mtaux_t *mt;
+ pthread_attr_t attr;
+ if (!fp->is_write || fp->mt || n_threads <= 1) return -1;
+ mt = (mtaux_t*)calloc(1, sizeof(mtaux_t));
+ mt->n_threads = n_threads;
+ mt->n_blks = n_threads * n_sub_blks;
+ mt->len = (int*)calloc(mt->n_blks, sizeof(int));
+ mt->blk = (void**)calloc(mt->n_blks, sizeof(void*));
+ for (i = 0; i < mt->n_blks; ++i)
+ mt->blk[i] = malloc(BGZF_MAX_BLOCK_SIZE);
+ mt->tid = (pthread_t*)calloc(mt->n_threads, sizeof(pthread_t)); // tid[0] is not used, as the worker 0 is launched by the master
+ mt->w = (worker_t*)calloc(mt->n_threads, sizeof(worker_t));
+ for (i = 0; i < mt->n_threads; ++i) {
+ mt->w[i].i = i;
+ mt->w[i].mt = mt;
+ mt->w[i].compress_level = fp->compress_level;
+ mt->w[i].buf = malloc(BGZF_MAX_BLOCK_SIZE);
+ }
+ pthread_attr_init(&attr);
+ pthread_attr_setdetachstate(&attr, PTHREAD_CREATE_JOINABLE);
+ pthread_mutex_init(&mt->lock, 0);
+ pthread_cond_init(&mt->cv, 0);
+ for (i = 1; i < mt->n_threads; ++i) // worker 0 is effectively launched by the master thread
+ pthread_create(&mt->tid[i], &attr, mt_worker, &mt->w[i]);
+ fp->mt = mt;
+ return 0;
+}
+
+static void mt_destroy(mtaux_t *mt)
+{
+ int i;
+ // signal all workers to quit
+ pthread_mutex_lock(&mt->lock);
+ mt->done = 1; mt->proc_cnt = 0;
+ pthread_cond_broadcast(&mt->cv);
+ pthread_mutex_unlock(&mt->lock);
+ for (i = 1; i < mt->n_threads; ++i) pthread_join(mt->tid[i], 0); // worker 0 is effectively launched by the master thread
+ // free other data allocated on heap
+ for (i = 0; i < mt->n_blks; ++i) free(mt->blk[i]);
+ for (i = 0; i < mt->n_threads; ++i) free(mt->w[i].buf);
+ free(mt->blk); free(mt->len); free(mt->w); free(mt->tid);
+ pthread_cond_destroy(&mt->cv);
+ pthread_mutex_destroy(&mt->lock);
+ free(mt);
+}
+
+static void mt_queue(BGZF *fp)
+{
+ mtaux_t *mt = fp->mt;
+ assert(mt->curr < mt->n_blks); // guaranteed by the caller
+ memcpy(mt->blk[mt->curr], fp->uncompressed_block, fp->block_offset);
+ mt->len[mt->curr] = fp->block_offset;
+ fp->block_offset = 0;
+ ++mt->curr;
+}
+
+static int mt_flush_queue(BGZF *fp)
+{
+ int i;
+ mtaux_t *mt = fp->mt;
+ // signal all the workers to compress
+ pthread_mutex_lock(&mt->lock);
+ for (i = 0; i < mt->n_threads; ++i) mt->w[i].toproc = 1;
+ mt->proc_cnt = 0;
+ pthread_cond_broadcast(&mt->cv);
+ pthread_mutex_unlock(&mt->lock);
+ // worker 0 is doing things here
+ worker_aux(&mt->w[0]);
+ // wait for all the threads to complete
+ while (mt->proc_cnt < mt->n_threads);
+ // dump data to disk
+ for (i = 0; i < mt->n_threads; ++i) fp->errcode |= mt->w[i].errcode;
+ if (fp->errcode == 0) {
+ /* Only try to write if all the threads worked, as otherwise we
+ could get a file with holes in it */
+ for (i = 0; i < mt->curr; ++i) {
+ if (hwrite(fp->fp, mt->blk[i], mt->len[i]) != mt->len[i]) {
+ fp->errcode |= BGZF_ERR_IO;
+ break;
+ }
+ }
+ }
+ mt->curr = 0;
+ return (fp->errcode == 0)? 0 : -1;
+}
+
+static int lazy_flush(BGZF *fp)
+{
+ if (fp->mt) {
+ if (fp->block_offset) mt_queue(fp);
+ return (fp->mt->curr < fp->mt->n_blks)? 0 : mt_flush_queue(fp);
+ }
+ else return bgzf_flush(fp);
+}
+
+#else // ~ #ifdef BGZF_MT
+
+int bgzf_mt(BGZF *fp, int n_threads, int n_sub_blks)
+{
+ return 0;
+}
+
+static inline int lazy_flush(BGZF *fp)
+{
+ return bgzf_flush(fp);
+}
+
+#endif // ~ #ifdef BGZF_MT
+
+int bgzf_flush(BGZF *fp)
+{
+ if (!fp->is_write) return 0;
+#ifdef BGZF_MT
+ if (fp->mt) {
+ if (fp->block_offset) mt_queue(fp); // guaranteed that assertion does not fail
+ return mt_flush_queue(fp);
+ }
+#endif
+ while (fp->block_offset > 0) {
+ int block_length;
+ if ( fp->idx_build_otf )
+ {
+ bgzf_index_add_block(fp);
+ fp->idx->ublock_addr += fp->block_offset;
+ }
+ block_length = deflate_block(fp, fp->block_offset);
+ if (block_length < 0) {
+ if (hts_verbose >= 3) fprintf(stderr, "[E::%s] deflate_block error %d\n", __func__, block_length);
+ return -1;
+ }
+ if (hwrite(fp->fp, fp->compressed_block, block_length) != block_length) {
+ if (hts_verbose >= 1) fprintf(stderr, "[E::%s] hwrite error (wrong size)\n", __func__);
+ fp->errcode |= BGZF_ERR_IO; // possibly truncated file
+ return -1;
+ }
+ fp->block_address += block_length;
+ }
+ return 0;
+}
+
+int bgzf_flush_try(BGZF *fp, ssize_t size)
+{
+ if (fp->block_offset + size > BGZF_BLOCK_SIZE) return lazy_flush(fp);
+ return 0;
+}
+
+ssize_t bgzf_write(BGZF *fp, const void *data, size_t length)
+{
+ if ( !fp->is_compressed )
+ return hwrite(fp->fp, data, length);
+
+ const uint8_t *input = (const uint8_t*)data;
+ ssize_t remaining = length;
+ assert(fp->is_write);
+ while (remaining > 0) {
+ uint8_t* buffer = (uint8_t*)fp->uncompressed_block;
+ int copy_length = BGZF_BLOCK_SIZE - fp->block_offset;
+ if (copy_length > remaining) copy_length = remaining;
+ memcpy(buffer + fp->block_offset, input, copy_length);
+ fp->block_offset += copy_length;
+ input += copy_length;
+ remaining -= copy_length;
+ if (fp->block_offset == BGZF_BLOCK_SIZE) {
+ if (lazy_flush(fp) != 0) return -1;
+ }
+ }
+ return length - remaining;
+}
+
+ssize_t bgzf_raw_write(BGZF *fp, const void *data, size_t length)
+{
+ return hwrite(fp->fp, data, length);
+}
+
+int bgzf_close(BGZF* fp)
+{
+ int ret, block_length;
+ if (fp == 0) return -1;
+ if (fp->is_write && fp->is_compressed) {
+ if (bgzf_flush(fp) != 0) return -1;
+ fp->compress_level = -1;
+ block_length = deflate_block(fp, 0); // write an empty block
+ if (block_length < 0) {
+ if (hts_verbose >= 3) fprintf(stderr, "[E::%s] deflate_block error %d\n", __func__, block_length);
+ return -1;
+ }
+ if (hwrite(fp->fp, fp->compressed_block, block_length) < 0
+ || hflush(fp->fp) != 0) {
+ if (hts_verbose >= 1) fprintf(stderr, "[E::%s] file write error\n", __func__);
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+#ifdef BGZF_MT
+ if (fp->mt) mt_destroy(fp->mt);
+#endif
+ }
+ if ( fp->is_gzip )
+ {
+ if (!fp->is_write) ret = inflateEnd(fp->gz_stream);
+ else ret = deflateEnd(fp->gz_stream);
+ if (ret != Z_OK && hts_verbose >= 1)
+ fprintf(stderr, "[E::%s] inflateEnd/deflateEnd failed: %s\n",
+ __func__, bgzf_zerr(ret, NULL));
+ free(fp->gz_stream);
+ }
+ ret = hclose(fp->fp);
+ if (ret != 0) return -1;
+ bgzf_index_destroy(fp);
+ free(fp->uncompressed_block);
+ free(fp->compressed_block);
+ free_cache(fp);
+ free(fp);
+ return 0;
+}
+
+void bgzf_set_cache_size(BGZF *fp, int cache_size)
+{
+ if (fp) fp->cache_size = cache_size;
+}
+
+int bgzf_check_EOF(BGZF *fp)
+{
+ uint8_t buf[28];
+ off_t offset = htell(fp->fp);
+ if (hseek(fp->fp, -28, SEEK_END) < 0) {
+ if (errno == ESPIPE) { hclearerr(fp->fp); return 2; }
+ else return -1;
+ }
+ if ( hread(fp->fp, buf, 28) != 28 ) return -1;
+ if ( hseek(fp->fp, offset, SEEK_SET) < 0 ) return -1;
+ return (memcmp("\037\213\010\4\0\0\0\0\0\377\6\0\102\103\2\0\033\0\3\0\0\0\0\0\0\0\0\0", buf, 28) == 0)? 1 : 0;
+}
+
+int64_t bgzf_seek(BGZF* fp, int64_t pos, int where)
+{
+ int block_offset;
+ int64_t block_address;
+
+ if (fp->is_write || where != SEEK_SET) {
+ fp->errcode |= BGZF_ERR_MISUSE;
+ return -1;
+ }
+ block_offset = pos & 0xFFFF;
+ block_address = pos >> 16;
+ if (hseek(fp->fp, block_address, SEEK_SET) < 0) {
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+ fp->block_length = 0; // indicates current block has not been loaded
+ fp->block_address = block_address;
+ fp->block_offset = block_offset;
+ return 0;
+}
+
+int bgzf_is_bgzf(const char *fn)
+{
+ uint8_t buf[16];
+ int n;
+ hFILE *fp;
+ if ((fp = hopen(fn, "r")) == 0) return 0;
+ n = hread(fp, buf, 16);
+ if ( hclose(fp) < 0 ) return -1;
+ if (n != 16) return 0;
+ return memcmp(g_magic, buf, 16) == 0? 1 : 0;
+}
+
+int bgzf_getc(BGZF *fp)
+{
+ int c;
+ if (fp->block_offset >= fp->block_length) {
+ if (bgzf_read_block(fp) != 0) return -2; /* error */
+ if (fp->block_length == 0) return -1; /* end-of-file */
+ }
+ c = ((unsigned char*)fp->uncompressed_block)[fp->block_offset++];
+ if (fp->block_offset == fp->block_length) {
+ fp->block_address = htell(fp->fp);
+ fp->block_offset = 0;
+ fp->block_length = 0;
+ }
+ fp->uncompressed_address++;
+ return c;
+}
+
+#ifndef kroundup32
+#define kroundup32(x) (--(x), (x)|=(x)>>1, (x)|=(x)>>2, (x)|=(x)>>4, (x)|=(x)>>8, (x)|=(x)>>16, ++(x))
+#endif
+
+int bgzf_getline(BGZF *fp, int delim, kstring_t *str)
+{
+ int l, state = 0;
+ unsigned char *buf = (unsigned char*)fp->uncompressed_block;
+ str->l = 0;
+ do {
+ if (fp->block_offset >= fp->block_length) {
+ if (bgzf_read_block(fp) != 0) { state = -2; break; }
+ if (fp->block_length == 0) { state = -1; break; }
+ }
+ for (l = fp->block_offset; l < fp->block_length && buf[l] != delim; ++l);
+ if (l < fp->block_length) state = 1;
+ l -= fp->block_offset;
+ if (str->l + l + 1 >= str->m) {
+ str->m = str->l + l + 2;
+ kroundup32(str->m);
+ str->s = (char*)realloc(str->s, str->m);
+ }
+ memcpy(str->s + str->l, buf + fp->block_offset, l);
+ str->l += l;
+ fp->block_offset += l + 1;
+ if (fp->block_offset >= fp->block_length) {
+ fp->block_address = htell(fp->fp);
+ fp->block_offset = 0;
+ fp->block_length = 0;
+ }
+ } while (state == 0);
+ if (str->l == 0 && state < 0) return state;
+ fp->uncompressed_address += str->l;
+ if ( delim=='\n' && str->l>0 && str->s[str->l-1]=='\r' ) str->l--;
+ str->s[str->l] = 0;
+ return str->l;
+}
+
+void bgzf_index_destroy(BGZF *fp)
+{
+ if ( !fp->idx ) return;
+ free(fp->idx->offs);
+ free(fp->idx);
+ fp->idx = NULL;
+ fp->idx_build_otf = 0;
+}
+
+int bgzf_index_build_init(BGZF *fp)
+{
+ bgzf_index_destroy(fp);
+ fp->idx = (bgzidx_t*) calloc(1,sizeof(bgzidx_t));
+ if ( !fp->idx ) return -1;
+ fp->idx_build_otf = 1; // build index on the fly
+ return 0;
+}
+
+int bgzf_index_add_block(BGZF *fp)
+{
+ fp->idx->noffs++;
+ if ( fp->idx->noffs > fp->idx->moffs )
+ {
+ fp->idx->moffs = fp->idx->noffs;
+ kroundup32(fp->idx->moffs);
+ fp->idx->offs = (bgzidx1_t*) realloc(fp->idx->offs, fp->idx->moffs*sizeof(bgzidx1_t));
+ if ( !fp->idx->offs ) return -1;
+ }
+ fp->idx->offs[ fp->idx->noffs-1 ].uaddr = fp->idx->ublock_addr;
+ fp->idx->offs[ fp->idx->noffs-1 ].caddr = fp->block_address;
+ return 0;
+}
+
+static inline int fwrite_uint64(uint64_t x, FILE *f)
+{
+ if (ed_is_big()) x = ed_swap_8(x);
+ if (fwrite(&x, sizeof x, 1, f) != 1) return -1;
+ return 0;
+}
+
+int bgzf_index_dump(BGZF *fp, const char *bname, const char *suffix)
+{
+ if (bgzf_flush(fp) != 0) return -1;
+
+ assert(fp->idx);
+ char *tmp = NULL;
+ if ( suffix )
+ {
+ int blen = strlen(bname);
+ int slen = strlen(suffix);
+ tmp = (char*) malloc(blen + slen + 1);
+ if ( !tmp ) return -1;
+ memcpy(tmp,bname,blen);
+ memcpy(tmp+blen,suffix,slen+1);
+ }
+
+ FILE *idx = fopen(tmp?tmp:bname,"wb");
+ if ( tmp ) free(tmp);
+ if ( !idx ) {
+ if (hts_verbose > 1)
+ {
+ fprintf(stderr, "[E::%s] Error opening %s%s : %s\n",
+ __func__, bname, suffix ? suffix : "", strerror(errno));
+ }
+ return -1;
+ }
+
+ // Note that the index contains one extra record when indexing files opened
+ // for reading. The terminating record is not present when opened for writing.
+ // This is not a bug.
+
+ int i;
+ if (fwrite_uint64(fp->idx->noffs - 1, idx) < 0) goto fail;
+ for (i=1; i<fp->idx->noffs; i++)
+ {
+ if (fwrite_uint64(fp->idx->offs[i].caddr, idx) < 0) goto fail;
+ if (fwrite_uint64(fp->idx->offs[i].uaddr, idx) < 0) goto fail;
+ }
+
+ if (fclose(idx) < 0)
+ {
+ if (hts_verbose > 1)
+ {
+ fprintf(stderr, "[E::%s] Error on closing %s%s : %s\n",
+ __func__, bname, suffix ? suffix : "", strerror(errno));
+ }
+ return -1;
+ }
+ return 0;
+
+ fail:
+ if (hts_verbose > 1)
+ {
+ fprintf(stderr, "[E::%s] Error writing to %s%s : %s\n",
+ __func__, bname, suffix ? suffix : "", strerror(errno));
+ }
+ fclose(idx);
+ return -1;
+}
+
+static inline int fread_uint64(uint64_t *xptr, FILE *f)
+{
+ if (fread(xptr, sizeof *xptr, 1, f) != 1) return -1;
+ if (ed_is_big()) ed_swap_8p(xptr);
+ return 0;
+}
+
+int bgzf_index_load(BGZF *fp, const char *bname, const char *suffix)
+{
+ char *tmp = NULL;
+ if ( suffix )
+ {
+ int blen = strlen(bname);
+ int slen = strlen(suffix);
+ tmp = (char*) malloc(blen + slen + 1);
+ if ( !tmp ) return -1;
+ memcpy(tmp,bname,blen);
+ memcpy(tmp+blen,suffix,slen+1);
+ }
+
+ FILE *idx = fopen(tmp?tmp:bname,"rb");
+ if ( tmp ) free(tmp);
+ if ( !idx ) {
+ if (hts_verbose > 1) {
+ fprintf(stderr, "[E::%s] Error opening %s%s : %s\n",
+ __func__, bname, suffix ? suffix : "", strerror(errno));
+ }
+ return -1;
+ }
+
+ fp->idx = (bgzidx_t*) calloc(1,sizeof(bgzidx_t));
+ if (fp->idx == NULL) goto fail;
+ uint64_t x;
+ if (fread_uint64(&x, idx) < 0) goto fail;
+
+ fp->idx->noffs = fp->idx->moffs = x + 1;
+ fp->idx->offs = (bgzidx1_t*) malloc(fp->idx->moffs*sizeof(bgzidx1_t));
+ if (fp->idx->offs == NULL) goto fail;
+ fp->idx->offs[0].caddr = fp->idx->offs[0].uaddr = 0;
+
+ int i;
+ for (i=1; i<fp->idx->noffs; i++)
+ {
+ if (fread_uint64(&fp->idx->offs[i].caddr, idx) < 0) goto fail;
+ if (fread_uint64(&fp->idx->offs[i].uaddr, idx) < 0) goto fail;
+ }
+
+ if (fclose(idx) != 0) goto fail;
+ return 0;
+
+ fail:
+ if (hts_verbose > 1)
+ {
+ fprintf(stderr, "[E::%s] Error reading %s%s : %s\n",
+ __func__, bname, suffix ? suffix : "", strerror(errno));
+ }
+ fclose(idx);
+ if (fp->idx) {
+ free(fp->idx->offs);
+ free(fp->idx);
+ fp->idx = NULL;
+ }
+ return -1;
+}
+
+int bgzf_useek(BGZF *fp, long uoffset, int where)
+{
+ if ( !fp->is_compressed )
+ {
+ if (hseek(fp->fp, uoffset, SEEK_SET) < 0)
+ {
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+ fp->block_length = 0; // indicates current block has not been loaded
+ fp->block_address = uoffset;
+ fp->block_offset = 0;
+ if (bgzf_read_block(fp) < 0) {
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+ fp->uncompressed_address = uoffset;
+ return 0;
+ }
+
+ if ( !fp->idx )
+ {
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+
+ // binary search
+ int ilo = 0, ihi = fp->idx->noffs - 1;
+ while ( ilo<=ihi )
+ {
+ int i = (ilo+ihi)*0.5;
+ if ( uoffset < fp->idx->offs[i].uaddr ) ihi = i - 1;
+ else if ( uoffset >= fp->idx->offs[i].uaddr ) ilo = i + 1;
+ else break;
+ }
+ int i = ilo-1;
+ if (hseek(fp->fp, fp->idx->offs[i].caddr, SEEK_SET) < 0)
+ {
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+ fp->block_length = 0; // indicates current block has not been loaded
+ fp->block_address = fp->idx->offs[i].caddr;
+ fp->block_offset = 0;
+ if ( bgzf_read_block(fp) < 0 ) {
+ fp->errcode |= BGZF_ERR_IO;
+ return -1;
+ }
+ if ( uoffset - fp->idx->offs[i].uaddr > 0 )
+ {
+ fp->block_offset = uoffset - fp->idx->offs[i].uaddr;
+ assert( fp->block_offset <= fp->block_length ); // todo: skipped, unindexed, blocks
+ }
+ fp->uncompressed_address = uoffset;
+ return 0;
+}
+
+long bgzf_utell(BGZF *fp)
+{
+ return fp->uncompressed_address; // currently maintained only when reading
+}
--- /dev/null
+/* bgzip.c -- Block compression/decompression utility.
+
+ Copyright (C) 2008, 2009 Broad Institute / Massachusetts Institute of Technology
+ Copyright (C) 2010, 2013-2016 Genome Research Ltd.
+
+ Permission is hereby granted, free of charge, to any person obtaining a copy
+ of this software and associated documentation files (the "Software"), to deal
+ in the Software without restriction, including without limitation the rights
+ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+ copies of the Software, and to permit persons to whom the Software is
+ furnished to do so, subject to the following conditions:
+
+ The above copyright notices and this permission notice shall be included in
+ all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+ IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+ FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+ AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+ LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+ OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
+ THE SOFTWARE.
+*/
+
+#include <config.h>
+
+#include <stdlib.h>
+#include <string.h>
+#include <stdio.h>
+#include <fcntl.h>
+#include <unistd.h>
+#include <errno.h>
+#include <stdarg.h>
+#include <getopt.h>
+#include <sys/stat.h>
+#include "htslib/bgzf.h"
+#include "htslib/hts.h"
+
+static const int WINDOW_SIZE = 64 * 1024;
+
+static void error(const char *format, ...)
+{
+ va_list ap;
+ va_start(ap, format);
+ vfprintf(stderr, format, ap);
+ va_end(ap);
+ exit(EXIT_FAILURE);
+}
+
+static int confirm_overwrite(const char *fn)
+{
+ int save_errno = errno;
+ int ret = 0;
+
+ if (isatty(STDIN_FILENO)) {
+ char c;
+ fprintf(stderr, "[bgzip] %s already exists; do you wish to overwrite (y or n)? ", fn);
+ if (scanf("%c", &c) == 1 && (c == 'Y' || c == 'y')) ret = 1;
+ }
+
+ errno = save_errno;
+ return ret;
+}
+
+static int bgzip_main_usage(void)
+{
+ fprintf(stderr, "\n");
+ fprintf(stderr, "Version: %s\n", hts_version());
+ fprintf(stderr, "Usage: bgzip [OPTIONS] [FILE] ...\n");
+ fprintf(stderr, "Options:\n");
+ fprintf(stderr, " -b, --offset INT decompress at virtual file pointer (0-based uncompressed offset)\n");
+ fprintf(stderr, " -c, --stdout write on standard output, keep original files unchanged\n");
+ fprintf(stderr, " -d, --decompress decompress\n");
+ fprintf(stderr, " -f, --force overwrite files without asking\n");
+ fprintf(stderr, " -h, --help give this help\n");
+ fprintf(stderr, " -i, --index compress and create BGZF index\n");
+ fprintf(stderr, " -I, --index-name FILE name of BGZF index file [file.gz.gzi]\n");
+ fprintf(stderr, " -r, --reindex (re)index compressed file\n");
+ fprintf(stderr, " -s, --size INT decompress INT bytes (uncompressed size)\n");
+ fprintf(stderr, " -@, --threads INT number of compression threads to use [1]\n");
+ fprintf(stderr, "\n");
+ return 1;
+}
+
+int main(int argc, char **argv)
+{
+ int c, compress, pstdout, is_forced, index = 0, reindex = 0;
+ BGZF *fp;
+ void *buffer;
+ long start, end, size;
+ char *index_fname = NULL;
+ int threads = 1;
+
+ static const struct option loptions[] =
+ {
+ {"help", no_argument, NULL, 'h'},
+ {"offset", required_argument, NULL, 'b'},
+ {"stdout", no_argument, NULL, 'c'},
+ {"decompress", no_argument, NULL, 'd'},
+ {"force", no_argument, NULL, 'f'},
+ {"index", no_argument, NULL, 'i'},
+ {"index-name", required_argument, NULL, 'I'},
+ {"reindex", no_argument, NULL, 'r'},
+ {"size", required_argument, NULL, 's'},
+ {"threads", required_argument, NULL, '@'},
+ {"version", no_argument, NULL, 1},
+ {NULL, 0, NULL, 0}
+ };
+
+ compress = 1; pstdout = 0; start = 0; size = -1; end = -1; is_forced = 0;
+ while((c = getopt_long(argc, argv, "cdh?fb:@:s:iI:r",loptions,NULL)) >= 0){
+ switch(c){
+ case 'd': compress = 0; break;
+ case 'c': pstdout = 1; break;
+ case 'b': start = atol(optarg); compress = 0; pstdout = 1; break;
+ case 's': size = atol(optarg); pstdout = 1; break;
+ case 'f': is_forced = 1; break;
+ case 'i': index = 1; break;
+ case 'I': index_fname = optarg; break;
+ case 'r': reindex = 1; compress = 0; break;
+ case '@': threads = atoi(optarg); break;
+ case 1:
+ printf(
+"bgzip (htslib) %s\n"
+"Copyright (C) 2016 Genome Research Ltd.\n", hts_version());
+ return EXIT_SUCCESS;
+ case 'h':
+ case '?': return bgzip_main_usage();
+ }
+ }
+ if (size >= 0) end = start + size;
+ if (end >= 0 && end < start) {
+ fprintf(stderr, "[bgzip] Illegal region: [%ld, %ld]\n", start, end);
+ return 1;
+ }
+ if (compress == 1) {
+ struct stat sbuf;
+ int f_src = fileno(stdin);
+
+ if ( argc>optind )
+ {
+ if ( stat(argv[optind],&sbuf)<0 )
+ {
+ fprintf(stderr, "[bgzip] %s: %s\n", strerror(errno), argv[optind]);
+ return 1;
+ }
+
+ if ((f_src = open(argv[optind], O_RDONLY)) < 0) {
+ fprintf(stderr, "[bgzip] %s: %s\n", strerror(errno), argv[optind]);
+ return 1;
+ }
+
+ if (pstdout)
+ fp = bgzf_open("-", "w");
+ else
+ {
+ char *name = malloc(strlen(argv[optind]) + 5);
+ strcpy(name, argv[optind]);
+ strcat(name, ".gz");
+ fp = bgzf_open(name, is_forced? "w" : "wx");
+ if (fp == NULL && errno == EEXIST && confirm_overwrite(name))
+ fp = bgzf_open(name, "w");
+ if (fp == NULL) {
+ fprintf(stderr, "[bgzip] can't create %s: %s\n", name, strerror(errno));
+ free(name);
+ return 1;
+ }
+ free(name);
+ }
+ }
+ else if (!pstdout && isatty(fileno((FILE *)stdout)) )
+ return bgzip_main_usage();
+ else if ( index && !index_fname )
+ {
+ fprintf(stderr, "[bgzip] Index file name expected when writing to stdout\n");
+ return 1;
+ }
+ else
+ fp = bgzf_open("-", "w");
+
+ if (threads > 1)
+ bgzf_mt(fp, threads, 256);
+
+ if ( index ) bgzf_index_build_init(fp);
+ buffer = malloc(WINDOW_SIZE);
+ while ((c = read(f_src, buffer, WINDOW_SIZE)) > 0)
+ if (bgzf_write(fp, buffer, c) < 0) error("Could not write %d bytes: Error %d\n", c, fp->errcode);
+ if ( index )
+ {
+ if (index_fname) {
+ if (bgzf_index_dump(fp, index_fname, NULL) < 0)
+ error("Could not write index to '%s'\n", index_fname);
+ } else {
+ if (bgzf_index_dump(fp, argv[optind], ".gz.gzi") < 0)
+ error("Could not write index to '%s.gz.gzi'", argv[optind]);
+ }
+ }
+ if (bgzf_close(fp) < 0) error("Close failed: Error %d", fp->errcode);
+ if (argc > optind && !pstdout) unlink(argv[optind]);
+ free(buffer);
+ close(f_src);
+ return 0;
+ }
+ else if ( reindex )
+ {
+ if ( argc>optind )
+ {
+ fp = bgzf_open(argv[optind], "r");
+ if ( !fp ) error("[bgzip] Could not open file: %s\n", argv[optind]);
+ }
+ else
+ {
+ if ( !index_fname ) error("[bgzip] Index file name expected when reading from stdin\n");
+ fp = bgzf_open("-", "r");
+ if ( !fp ) error("[bgzip] Could not read from stdin: %s\n", strerror(errno));
+ }
+
+ buffer = malloc(BGZF_BLOCK_SIZE);
+ bgzf_index_build_init(fp);
+ int ret;
+ while ( (ret=bgzf_read(fp, buffer, BGZF_BLOCK_SIZE))>0 ) ;
+ free(buffer);
+ if ( ret<0 ) error("Is the file gzipped or bgzipped? The latter is required for indexing.\n");
+
+ if ( index_fname ) {
+ if (bgzf_index_dump(fp, index_fname, NULL) < 0)
+ error("Could not write index to '%s'\n", index_fname);
+ } else {
+ if (bgzf_index_dump(fp, argv[optind], ".gzi") < 0)
+ error("Could not write index to '%s.gzi'\n", argv[optind]);
+ }
+
+ if ( bgzf_close(fp)<0 ) error("Close failed: Error %d\n",fp->errcode);
+ return 0;
+ }
+ else
+ {
+ struct stat sbuf;
+ int f_dst;
+
+ if ( argc>optind )
+ {
+ if ( stat(argv[optind],&sbuf)<0 )
+ {
+ fprintf(stderr, "[bgzip] %s: %s\n", strerror(errno), argv[optind]);
+ return 1;
+ }
+ char *name;
+ int len = strlen(argv[optind]);
+ if ( strcmp(argv[optind]+len-3,".gz") )
+ {
+ fprintf(stderr, "[bgzip] %s: unknown suffix -- ignored\n", argv[optind]);
+ return 1;
+ }
+ fp = bgzf_open(argv[optind], "r");
+ if (fp == NULL) {
+ fprintf(stderr, "[bgzip] Could not open file: %s\n", argv[optind]);
+ return 1;
+ }
+
+ if (pstdout) {
+ f_dst = fileno(stdout);
+ }
+ else {
+ const int wrflags = O_WRONLY | O_CREAT | O_TRUNC;
+ name = strdup(argv[optind]);
+ name[strlen(name) - 3] = '\0';
+ f_dst = open(name, is_forced? wrflags : wrflags|O_EXCL, 0666);
+ if (f_dst < 0 && errno == EEXIST && confirm_overwrite(name))
+ f_dst = open(name, wrflags, 0666);
+ if (f_dst < 0) {
+ fprintf(stderr, "[bgzip] can't create %s: %s\n", name, strerror(errno));
+ free(name);
+ return 1;
+ }
+ free(name);
+ }
+ }
+ else if (!pstdout && isatty(fileno((FILE *)stdin)) )
+ return bgzip_main_usage();
+ else
+ {
+ f_dst = fileno(stdout);
+ fp = bgzf_open("-", "r");
+ if (fp == NULL) {
+ fprintf(stderr, "[bgzip] Could not read from stdin: %s\n", strerror(errno));
+ return 1;
+ }
+ }
+ buffer = malloc(WINDOW_SIZE);
+ if ( start>0 )
+ {
+ if ( bgzf_index_load(fp, argv[optind], ".gzi") < 0 ) error("Could not load index: %s.gzi\n", argv[optind]);
+ if ( bgzf_useek(fp, start, SEEK_SET) < 0 ) error("Could not seek to %d-th (uncompressd) byte\n", start);
+ }
+ while (1) {
+ if (end < 0) c = bgzf_read(fp, buffer, WINDOW_SIZE);
+ else c = bgzf_read(fp, buffer, (end - start > WINDOW_SIZE)? WINDOW_SIZE:(end - start));
+ if (c == 0) break;
+ if (c < 0) error("Could not read %d bytes: Error %d\n", (end - start > WINDOW_SIZE)? WINDOW_SIZE:(end - start), fp->errcode);
+ start += c;
+ if ( write(f_dst, buffer, c) != c ) error("Could not write %d bytes\n", c);
+ if (end >= 0 && start >= end) break;
+ }
+ free(buffer);
+ if (bgzf_close(fp) < 0) error("Close failed: Error %d\n",fp->errcode);
+ if (!pstdout) unlink(argv[optind]);
+ return 0;
+ }
+ return 0;
+}
--- /dev/null
+/* config.h.in -- template for config.h. If you use configure, this file
+ provides #defines reflecting your configuration choices. If you don't
+ run configure, suitable conservative defaults will be used.
+
+ This template file can be updated with autoheader, but do so carefully
+ as autoheader adds #defines such as PACKAGE_* that we don't want. */
+
+/* Define if HTSlib should enable plugins. */
+#undef ENABLE_PLUGINS
+
+/* Define if you have the Common Crypto library. */
+#undef HAVE_COMMONCRYPTO
+
+/* Define to 1 if you have the `gmtime_r' function. */
+#undef HAVE_GMTIME_R
+
+/* Define if you have libcrypto-style HMAC(). */
+#undef HAVE_HMAC
+
+/* Define to 1 if iRODS file access is enabled. */
+#undef HAVE_IRODS
+
+/* Define if libcurl file access is enabled. */
+#undef HAVE_LIBCURL
+
+/* Define to 1 if you have a working `mmap' system call. */
+#undef HAVE_MMAP
+
+/* Enable large inode numbers on Mac OS X 10.5. */
+#ifndef _DARWIN_USE_64_BIT_INODE
+# define _DARWIN_USE_64_BIT_INODE 1
+#endif
+
+/* Number of bits in a file offset, on hosts where this is settable. */
+#undef _FILE_OFFSET_BITS
+
+/* Define for large files, on AIX-style hosts. */
+#undef _LARGE_FILES
--- /dev/null
+# Optional configure Makefile overrides for htslib.
+#
+# Copyright (C) 2015 Genome Research Ltd.
+#
+# Author: John Marshall <jm18@sanger.ac.uk>
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in
+# all copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+# DEALINGS IN THE SOFTWARE.
+
+# This is @configure_input@
+#
+# If you use configure, this file overrides variables and augments rules
+# in the Makefile to reflect your configuration choices. If you don't run
+# configure, the main Makefile contains suitable conservative defaults.
+
+prefix = @prefix@
+exec_prefix = @exec_prefix@
+bindir = @bindir@
+includedir = @includedir@
+libdir = @libdir@
+libexecdir = @libexecdir@
+datarootdir = @datarootdir@
+mandir = @mandir@
+
+CC = @CC@
+RANLIB = @RANLIB@
+
+CPPFLAGS = @CPPFLAGS@
+CFLAGS = @CFLAGS@
+LDFLAGS = @LDFLAGS@
+LIBS = @LIBS@
+
+# Lowercase here indicates these are "local" to config.mk
+plugin_OBJS =
+noplugin_LDFLAGS =
+noplugin_LIBS =
+
+# ifeq/.../endif, +=, and target-specific variables are GNU Make-specific.
+# If you don't have GNU Make, comment out this conditional and note that
+# to enable iRODS you will need to implement the following elsewhere.
+ifeq "iRODS-@irods@" "iRODS-enabled"
+
+@define_IRODS_HOME@
+
+IRODS_CPPFLAGS = \
+ -I$(IRODS_HOME)/lib/api/include \
+ -I$(IRODS_HOME)/lib/core/include \
+ -I$(IRODS_HOME)/lib/md5/include \
+ -I$(IRODS_HOME)/lib/sha1/include \
+ -I$(IRODS_HOME)/server/core/include \
+ -I$(IRODS_HOME)/server/drivers/include \
+ -I$(IRODS_HOME)/server/icat/include
+
+IRODS_LDFLAGS = -L$(IRODS_HOME)/lib/core/obj
+IRODS_LIBS = -lRodsAPIs -lgssapi_krb5
+
+plugin_OBJS += hfile_irods.o
+
+hfile_irods.o hfile_irods.pico: CPPFLAGS += $(IRODS_CPPFLAGS)
+hfile_irods.so hfile_irods.bundle: LDFLAGS += $(IRODS_LDFLAGS)
+hfile_irods.so hfile_irods.bundle: LIBS += $(IRODS_LIBS)
+
+noplugin_LDFLAGS += $(IRODS_LDFLAGS)
+noplugin_LIBS += $(IRODS_LIBS)
+
+endif
+
+ifeq "libcurl-@libcurl@" "libcurl-enabled"
+
+LIBCURL_LIBS = -lcurl @CRYPTO_LIBS@
+
+plugin_OBJS += hfile_libcurl.o
+
+hfile_libcurl.so hfile_libcurl.bundle: LIBS += $(LIBCURL_LIBS)
+
+noplugin_LIBS += $(LIBCURL_LIBS)
+
+endif
+
+ifeq "plugins-@enable_plugins@" "plugins-yes"
+
+plugindir = @plugindir@
+pluginpath = @pluginpath@
+
+LIBHTS_OBJS += plugin.o
+PLUGIN_OBJS += $(plugin_OBJS)
+
+plugin.o plugin.pico: CPPFLAGS += -DPLUGINPATH=\"$(pluginpath)\"
+
+else
+
+LIBHTS_OBJS += $(plugin_OBJS)
+LDFLAGS += $(noplugin_LDFLAGS)
+LIBS += $(noplugin_LIBS)
+
+endif
--- /dev/null
+# Configure script for htslib, a C library for high-throughput sequencing data.
+#
+# Copyright (C) 2015 Genome Research Ltd.
+#
+# Author: John Marshall <jm18@sanger.ac.uk>
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in
+# all copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+# DEALINGS IN THE SOFTWARE.
+
+dnl Process this file with autoconf to produce a configure script
+AC_INIT([HTSlib], m4_esyscmd_s([make print-version]),
+ [samtools-help@lists.sourceforge.net], [], [http://www.htslib.org/])
+AC_PREREQ(2.63) dnl This version introduced 4-argument AC_CHECK_HEADER
+AC_CONFIG_SRCDIR(hts.c)
+AC_CONFIG_HEADERS(config.h)
+
+dnl Copyright notice to be copied into the generated configure script
+AC_COPYRIGHT([Portions copyright (C) 2015 Genome Research Ltd.
+
+This configure script is free software: you are free to change and
+redistribute it. There is NO WARRANTY, to the extent permitted by law.])
+
+AC_PROG_CC
+AC_PROG_RANLIB
+
+AC_SYS_LARGEFILE
+
+need_crypto=no
+
+AC_ARG_WITH([irods],
+ [AS_HELP_STRING([[--with-irods[=DIR]]],
+ [use RodsAPIs library (in DIR) to support iRODS URLs])],
+ [case $withval in
+ no) irods=disabled ;;
+ yes) irods=enabled ;;
+ *) irods=enabled; IRODS_HOME=$withval ;;
+ esac],
+ [irods=disabled])
+
+AC_ARG_ENABLE([libcurl],
+ [AS_HELP_STRING([--enable-libcurl],
+ [enable libcurl-based support for http/https/etc URLs])],
+ [], [enable_libcurl=no])
+
+AC_ARG_ENABLE([plugins],
+ [AS_HELP_STRING([--enable-plugins],
+ [enable separately-compiled plugins for file access])],
+ [], [enable_plugins=no])
+AC_SUBST(enable_plugins)
+
+AC_ARG_WITH([plugin-dir],
+ [AS_HELP_STRING([--with-plugin-dir=DIR],
+ [plugin installation location [LIBEXECDIR/htslib]])],
+ [case $withval in
+ yes|no) AC_MSG_ERROR([no directory specified for --with-plugin-dir]) ;;
+ esac],
+ [with_plugin_dir='$(libexecdir)/htslib'])
+AC_SUBST([plugindir], $with_plugin_dir)
+
+AC_ARG_WITH([plugin-path],
+ [AS_HELP_STRING([--with-plugin-path=PATH],
+ [default HTS_PATH plugin search path [PLUGINDIR]])],
+ [case $withval in
+ yes) AC_MSG_ERROR([no path specified for --with-plugin-path]) ;;
+ no) with_plugin_path= ;;
+ esac],
+ [with_plugin_path=$with_plugin_dir])
+AC_SUBST([pluginpath], $with_plugin_path)
+
+dnl FIXME This pulls in dozens of standard header checks
+AC_FUNC_MMAP
+AC_CHECK_FUNCS(gmtime_r)
+
+if test $enable_plugins != no; then
+ AC_SEARCH_LIBS([dlopen], [dl], [],
+ [AC_MSG_ERROR([dlopen() not found
+
+Plugin support requires dynamic linking facilities from the operating system.
+Either configure with --disable-plugins or resolve this error to build HTSlib.])])
+ # TODO Test whether this is required and/or needs tweaking per-platform
+ LDFLAGS="$LDFLAGS -rdynamic"
+ AC_DEFINE([ENABLE_PLUGINS], 1, [Define if HTSlib should enable plugins.])
+fi
+
+save_LIBS=$LIBS
+zlib_devel=ok
+dnl Set a trivial non-empty INCLUDES to avoid excess default includes tests
+AC_CHECK_HEADER([zlib.h], [], [zlib_devel=missing], [;])
+AC_CHECK_LIB(z, inflate, [], [zlib_devel=missing])
+LIBS=$save_LIBS
+
+if test $zlib_devel != ok; then
+ AC_MSG_ERROR([zlib development files not found
+
+HTSlib uses compression routines from the zlib library <http://zlib.net>.
+Building HTSlib requires zlib development files to be installed on the build
+machine; you may need to ensure a package such as zlib1g-dev (on Debian or
+Ubuntu Linux) or zlib-devel (on RPM-based Linux distributions) is installed.
+
+FAILED. This error must be resolved in order to build HTSlib successfully.])
+fi
+
+if test $irods = enabled; then
+ # TODO Also test whether we require libgssapi_krb5 and AC_CHECK_LIB it
+ save_LDFLAGS=$LDFLAGS
+ LDFLAGS="$LDFLAGS -L$IRODS_HOME/lib/core/obj"
+ AC_CHECK_LIB([RodsAPIs], [getRodsEnvFileName],
+ [case $with_irods in
+ yes) define_IRODS_HOME='# Uses $(IRODS_HOME) from the environment' ;;
+ *) define_IRODS_HOME="IRODS_HOME = $with_irods" ;;
+ esac],
+ [AC_MSG_ERROR([iRODS development files not found
+
+Support for iRODS URLs requires the libRodsAPI client library and headers.
+Configure with --with-irods=DIR (or just --with-irods if \$IRODS_HOME has
+been exported with a suitable value), where DIR is the base of an iRODS tree
+such that the library is present as DIR/lib/core/obj/libRodsAPI.* and headers
+are present under DIR/lib/api/include and so on.])],
+ [-lgssapi_krb5 -lpthread])
+ LDFLAGS=$save_LDFLAGS
+ AC_DEFINE([HAVE_IRODS], 1, [Define to 1 if iRODS file access is enabled.])
+else
+ define_IRODS_HOME='IRODS_HOME ?= /disabled'
+fi
+AC_SUBST([irods])
+AC_SUBST([define_IRODS_HOME])
+
+libcurl=disabled
+if test "$enable_libcurl" != no; then
+ AC_CHECK_LIB([curl], [curl_easy_pause],
+ [AC_DEFINE([HAVE_LIBCURL], 1, [Define if libcurl file access is enabled.])
+ libcurl=enabled],
+ [AC_CHECK_LIB([curl], [curl_easy_init],
+ [message="library is too old (7.18+ required)"],
+ [message="library not found"])
+ case "$enable_libcurl" in
+ check) AC_MSG_WARN([libcurl not enabled: $message]) ;;
+ *) AC_MSG_ERROR([libcurl $message
+
+Support for HTTPS and other SSL-based URLs requires routines from the libcurl
+library <http://curl.haxx.se/libcurl/>. Building HTSlib with libcurl enabled
+requires libcurl development files to be installed on the build machine; you
+may need to ensure a package such as libcurl4-{gnutls,nss,openssl}-dev (on
+Debian or Ubuntu Linux) or libcurl-devel (on RPM-based Linux distributions)
+is installed.
+
+Either configure with --disable-libcurl or resolve this error to build HTSlib.])
+ ;;
+ esac])
+ need_crypto=yes
+fi
+AC_SUBST([libcurl])
+
+CRYPTO_LIBS=
+if test $need_crypto != no; then
+ AC_CHECK_FUNC([CCHmac],
+ [AC_DEFINE([HAVE_COMMONCRYPTO], 1,
+ [Define if you have the Common Crypto library.])],
+ [save_LIBS=$LIBS
+ AC_SEARCH_LIBS([HMAC], [crypto],
+ [AC_DEFINE([HAVE_HMAC], 1, [Define if you have libcrypto-style HMAC().])
+ case "$ac_cv_search_HMAC" in
+ -l*) CRYPTO_LIBS=$ac_cv_search_HMAC ;;
+ esac],
+ [AC_MSG_ERROR([SSL development files not found
+
+Support for AWS S3 URLs requires routines from an SSL library. Building
+HTSlib with libcurl enabled requires SSL development files to be installed
+on the build machine; you may need to ensure a package such as libgnutls-dev,
+libnss3-dev, or libssl-dev (on Debian or Ubuntu Linux, corresponding to the
+libcurl4-*-dev package installed) or similar on RPM-based Linux distributions.
+
+Either configure with --disable-libcurl or resolve this error to build HTSlib.])])
+ LIBS=$save_LIBS])
+fi
+AC_SUBST([CRYPTO_LIBS])
+
+AC_CONFIG_FILES(config.mk)
+AC_OUTPUT
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*! \file
+ * CRAM interface.
+ *
+ * Consider using the higher level hts_*() API for programs that wish to
+ * be file format agnostic (see htslib/hts.h).
+ *
+ * This API should be used for CRAM specific code. The specifics of the
+ * public API are implemented in cram_io.h, cram_encode.h and cram_decode.h
+ * although these should not be included directly (use this file instead).
+ */
+
+#ifndef _CRAM_H_
+#define _CRAM_H_
+
+#include "cram/cram_samtools.h"
+#include "cram/sam_header.h"
+#include "cram_structs.h"
+#include "cram_io.h"
+#include "cram_encode.h"
+#include "cram_decode.h"
+#include "cram_stats.h"
+#include "cram_codecs.h"
+#include "cram_index.h"
+
+// Validate against the external cram.h,
+//
+// This contains duplicated portions from cram_io.h and cram_structs.h,
+// so we want to ensure that the prototypes match.
+#include "htslib/cram.h"
+
+#endif
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+ * FIXME: add checking of cram_external_type to return NULL on unsupported
+ * {codec,type} tuples.
+ */
+
+#include <config.h>
+
+#include <stdlib.h>
+#include <string.h>
+#include <assert.h>
+#include <limits.h>
+
+#include "cram/cram.h"
+
+/*
+ * ---------------------------------------------------------------------------
+ * Block bit-level I/O functions.
+ * All defined static here to promote easy inlining by the compiler.
+ */
+
+#if 0
+/* Get a single bit, MSB first */
+static signed int get_bit_MSB(cram_block *block) {
+ unsigned int val;
+
+ if (block->byte > block->alloc)
+ return -1;
+
+ val = block->data[block->byte] >> block->bit;
+ if (--block->bit == -1) {
+ block->bit = 7;
+ block->byte++;
+ //printf("(%02X)", block->data[block->byte]);
+ }
+
+ //printf("-B%d-", val&1);
+
+ return val & 1;
+}
+#endif
+
+/*
+ * Count number of successive 0 and 1 bits
+ */
+static int get_one_bits_MSB(cram_block *block) {
+ int n = 0, b;
+ if (block->byte >= block->uncomp_size)
+ return -1;
+ do {
+ b = block->data[block->byte] >> block->bit;
+ if (--block->bit == -1) {
+ block->bit = 7;
+ block->byte++;
+ if (block->byte == block->uncomp_size && (b&1))
+ return -1;
+ }
+ n++;
+ } while (b&1);
+
+ return n-1;
+}
+
+static int get_zero_bits_MSB(cram_block *block) {
+ int n = 0, b;
+ if (block->byte >= block->uncomp_size)
+ return -1;
+ do {
+ b = block->data[block->byte] >> block->bit;
+ if (--block->bit == -1) {
+ block->bit = 7;
+ block->byte++;
+ if (block->byte == block->uncomp_size && !(b&1))
+ return -1;
+ }
+ n++;
+ } while (!(b&1));
+
+ return n-1;
+}
+
+#if 0
+/* Stores a single bit */
+static void store_bit_MSB(cram_block *block, unsigned int bit) {
+ if (block->byte >= block->alloc) {
+ block->alloc = block->alloc ? block->alloc*2 : 1024;
+ block->data = realloc(block->data, block->alloc);
+ }
+
+ if (bit)
+ block->data[block->byte] |= (1 << block->bit);
+
+ if (--block->bit == -1) {
+ block->bit = 7;
+ block->byte++;
+ block->data[block->byte] = 0;
+ }
+}
+#endif
+
+#if 0
+/* Rounds to the next whole byte boundary first */
+static void store_bytes_MSB(cram_block *block, char *bytes, int len) {
+ if (block->bit != 7) {
+ block->bit = 7;
+ block->byte++;
+ }
+
+ while (block->byte + len >= block->alloc) {
+ block->alloc = block->alloc ? block->alloc*2 : 1024;
+ block->data = realloc(block->data, block->alloc);
+ }
+
+ memcpy(&block->data[block->byte], bytes, len);
+ block->byte += len;
+}
+#endif
+
+/* Local optimised copy for inlining */
+static inline unsigned int get_bits_MSB(cram_block *block, int nbits) {
+ unsigned int val = 0;
+ int i;
+
+#if 0
+ // Fits within the current byte */
+ if (nbits <= block->bit+1) {
+ val = (block->data[block->byte]>>(block->bit-(nbits-1))) & ((1<<nbits)-1);
+ if ((block->bit -= nbits) == -1) {
+ block->bit = 7;
+ block->byte++;
+ }
+ return val;
+ }
+
+ // partial first byte
+ val = block->data[block->byte] & ((1<<(block->bit+1))-1);
+ nbits -= block->bit+1;
+ block->bit = 7;
+ block->byte++;
+
+ // whole middle bytes
+ while (nbits >= 8) {
+ val = (val << 8) | block->data[block->byte++];
+ nbits -= 8;
+ }
+
+ val <<= nbits;
+ val |= (block->data[block->byte]>>(block->bit-(nbits-1))) & ((1<<nbits)-1);
+ block->bit -= nbits;
+ return val;
+#endif
+
+#if 0
+ /* Inefficient implementation! */
+ //printf("{");
+ for (i = 0; i < nbits; i++)
+ //val = (val << 1) | get_bit_MSB(block);
+ GET_BIT_MSB(block, val);
+#endif
+
+#if 1
+ /* Combination of 1st two methods */
+ if (nbits <= block->bit+1) {
+ val = (block->data[block->byte]>>(block->bit-(nbits-1))) & ((1<<nbits)-1);
+ if ((block->bit -= nbits) == -1) {
+ block->bit = 7;
+ block->byte++;
+ }
+ return val;
+ }
+
+ switch(nbits) {
+// case 15: GET_BIT_MSB(block, val);
+// case 14: GET_BIT_MSB(block, val);
+// case 13: GET_BIT_MSB(block, val);
+// case 12: GET_BIT_MSB(block, val);
+// case 11: GET_BIT_MSB(block, val);
+// case 10: GET_BIT_MSB(block, val);
+// case 9: GET_BIT_MSB(block, val);
+ case 8: GET_BIT_MSB(block, val);
+ case 7: GET_BIT_MSB(block, val);
+ case 6: GET_BIT_MSB(block, val);
+ case 5: GET_BIT_MSB(block, val);
+ case 4: GET_BIT_MSB(block, val);
+ case 3: GET_BIT_MSB(block, val);
+ case 2: GET_BIT_MSB(block, val);
+ case 1: GET_BIT_MSB(block, val);
+ break;
+
+ default:
+ for (i = 0; i < nbits; i++)
+ //val = (val << 1) | get_bit_MSB(block);
+ GET_BIT_MSB(block, val);
+ }
+#endif
+
+ //printf("=0x%x}", val);
+
+ return val;
+}
+
+/*
+ * Can store up to 24-bits worth of data encoded in an integer value
+ * Possibly we'd want to have a less optimal store_bits function when dealing
+ * with nbits > 24, but for now we assume the codes generated are never
+ * that big. (Given this is only possible with 121392 or more
+ * characters with exactly the correct frequency distribution we check
+ * for it elsewhere.)
+ */
+static int store_bits_MSB(cram_block *block, unsigned int val, int nbits) {
+ /* fprintf(stderr, " store_bits: %02x %d\n", val, nbits); */
+
+ /*
+ * Use slow mode until we tweak the huffman generator to never generate
+ * codes longer than 24-bits.
+ */
+ unsigned int mask;
+
+ if (block->byte+4 >= block->alloc) {
+ if (block->byte) {
+ block->alloc *= 2;
+ block->data = realloc(block->data, block->alloc + 4);
+ if (!block->data)
+ return -1;
+ } else {
+ block->alloc = 1024;
+ block->data = realloc(block->data, block->alloc + 4);
+ if (!block->data)
+ return -1;
+ block->data[0] = 0; // initialise first byte of buffer
+ }
+ }
+
+ /* fits in current bit-field */
+ if (nbits <= block->bit+1) {
+ block->data[block->byte] |= (val << (block->bit+1-nbits));
+ if ((block->bit-=nbits) == -1) {
+ block->bit = 7;
+ block->byte++;
+ block->data[block->byte] = 0;
+ }
+ return 0;
+ }
+
+ block->data[block->byte] |= (val >> (nbits -= block->bit+1));
+ block->bit = 7;
+ block->byte++;
+ block->data[block->byte] = 0;
+
+ mask = 1<<(nbits-1);
+ do {
+ if (val & mask)
+ block->data[block->byte] |= (1 << block->bit);
+ if (--block->bit == -1) {
+ block->bit = 7;
+ block->byte++;
+ block->data[block->byte] = 0;
+ }
+ mask >>= 1;
+ } while(--nbits);
+
+ return 0;
+}
+
+/*
+ * Returns the next 'size' bytes from a block, or NULL if insufficient
+ * data left.This is just a pointer into the block data and not an
+ * allocated object, so do not free the result.
+ */
+static char *cram_extract_block(cram_block *b, int size) {
+ char *cp = (char *)b->data + b->idx;
+ b->idx += size;
+ if (b->idx > b->uncomp_size)
+ return NULL;
+
+ return cp;
+}
+
+/*
+ * ---------------------------------------------------------------------------
+ * EXTERNAL
+ */
+int cram_external_decode_int(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out, int *out_size) {
+ int l;
+ char *cp;
+ cram_block *b;
+
+ /* Find the external block */
+ b = cram_get_block_by_id(slice, c->external.content_id);
+ if (!b)
+ return *out_size?-1:0;
+
+ cp = (char *)b->data + b->idx;
+ // E_INT and E_LONG are guaranteed single item queries
+ l = safe_itf8_get(cp, (char *)b->data + b->uncomp_size, (int32_t *)out);
+ b->idx += l;
+ *out_size = 1;
+
+ return l > 0 ? 0 : -1;
+}
+
+int cram_external_decode_char(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out,
+ int *out_size) {
+ char *cp;
+ cram_block *b;
+
+ /* Find the external block */
+ b = cram_get_block_by_id(slice, c->external.content_id);
+ if (!b)
+ return *out_size?-1:0;
+
+ cp = cram_extract_block(b, *out_size);
+ if (!cp)
+ return -1;
+
+ if (out)
+ memcpy(out, cp, *out_size);
+ return 0;
+}
+
+static int cram_external_decode_block(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out_,
+ int *out_size) {
+ char *cp;
+ cram_block *b = NULL;
+ cram_block *out = (cram_block *)out_;
+
+ /* Find the external block */
+ b = cram_get_block_by_id(slice, c->external.content_id);
+ if (!b)
+ return *out_size?-1:0;
+
+ cp = cram_extract_block(b, *out_size);
+ if (!cp)
+ return -1;
+
+ BLOCK_APPEND(out, cp, *out_size);
+ return 0;
+}
+
+void cram_external_decode_free(cram_codec *c) {
+ if (c)
+ free(c);
+}
+
+cram_codec *cram_external_decode_init(char *data, int size,
+ enum cram_external_type option,
+ int version) {
+ cram_codec *c;
+ char *cp = data;
+
+ if (!(c = malloc(sizeof(*c))))
+ return NULL;
+
+ c->codec = E_EXTERNAL;
+ if (option == E_INT || option == E_LONG)
+ c->decode = cram_external_decode_int;
+ else if (option == E_BYTE_ARRAY || option == E_BYTE)
+ c->decode = cram_external_decode_char;
+ else
+ c->decode = cram_external_decode_block;
+ c->free = cram_external_decode_free;
+
+ cp += itf8_get(cp, &c->external.content_id);
+
+ if (cp - data != size) {
+ fprintf(stderr, "Malformed external header stream\n");
+ free(c);
+ return NULL;
+ }
+
+ c->external.type = option;
+
+ return c;
+}
+
+int cram_external_encode_int(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ uint32_t *i32 = (uint32_t *)in;
+
+ itf8_put_blk(c->out, *i32);
+ return 0;
+}
+
+int cram_external_encode_char(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ BLOCK_APPEND(c->out, in, in_size);
+ return 0;
+}
+
+void cram_external_encode_free(cram_codec *c) {
+ if (!c)
+ return;
+ free(c);
+}
+
+int cram_external_encode_store(cram_codec *c, cram_block *b, char *prefix,
+ int version) {
+ char tmp[99], *tp = tmp;
+ int len = 0;
+
+ if (prefix) {
+ size_t l = strlen(prefix);
+ BLOCK_APPEND(b, prefix, l);
+ len += l;
+ }
+
+ tp += itf8_put(tp, c->e_external.content_id);
+ len += itf8_put_blk(b, c->codec);
+ len += itf8_put_blk(b, tp-tmp);
+ BLOCK_APPEND(b, tmp, tp-tmp);
+ len += tp-tmp;
+
+ return len;
+}
+
+cram_codec *cram_external_encode_init(cram_stats *st,
+ enum cram_external_type option,
+ void *dat,
+ int version) {
+ cram_codec *c;
+
+ c = malloc(sizeof(*c));
+ if (!c)
+ return NULL;
+ c->codec = E_EXTERNAL;
+ c->free = cram_external_encode_free;
+ if (option == E_INT || option == E_LONG)
+ c->encode = cram_external_encode_int;
+ else if (option == E_BYTE_ARRAY || option == E_BYTE)
+ c->encode = cram_external_encode_char;
+ else
+ abort();
+ c->store = cram_external_encode_store;
+
+ c->e_external.content_id = (size_t)dat;
+
+ return c;
+}
+
+/*
+ * ---------------------------------------------------------------------------
+ * BETA
+ */
+int cram_beta_decode_int(cram_slice *slice, cram_codec *c, cram_block *in, char *out, int *out_size) {
+ int32_t *out_i = (int32_t *)out;
+ int i, n;
+
+ if (c->beta.nbits) {
+ if (cram_not_enough_bits(in, c->beta.nbits))
+ return -1;
+
+ for (i = 0, n = *out_size; i < n; i++)
+ out_i[i] = get_bits_MSB(in, c->beta.nbits) - c->beta.offset;
+ } else {
+ for (i = 0, n = *out_size; i < n; i++)
+ out_i[i] = -c->beta.offset;
+ }
+
+ return 0;
+}
+
+int cram_beta_decode_char(cram_slice *slice, cram_codec *c, cram_block *in, char *out, int *out_size) {
+ int i, n;
+
+
+ if (c->beta.nbits) {
+ if (cram_not_enough_bits(in, c->beta.nbits))
+ return -1;
+
+ if (out)
+ for (i = 0, n = *out_size; i < n; i++)
+ out[i] = get_bits_MSB(in, c->beta.nbits) - c->beta.offset;
+ else
+ for (i = 0, n = *out_size; i < n; i++)
+ get_bits_MSB(in, c->beta.nbits);
+ } else {
+ if (out)
+ for (i = 0, n = *out_size; i < n; i++)
+ out[i] = -c->beta.offset;
+ }
+
+ return 0;
+}
+
+void cram_beta_decode_free(cram_codec *c) {
+ if (c)
+ free(c);
+}
+
+cram_codec *cram_beta_decode_init(char *data, int size,
+ enum cram_external_type option,
+ int version) {
+ cram_codec *c;
+ char *cp = data;
+
+ if (!(c = malloc(sizeof(*c))))
+ return NULL;
+
+ c->codec = E_BETA;
+ if (option == E_INT || option == E_LONG)
+ c->decode = cram_beta_decode_int;
+ else if (option == E_BYTE_ARRAY || option == E_BYTE)
+ c->decode = cram_beta_decode_char;
+ else
+ abort();
+ c->free = cram_beta_decode_free;
+
+ cp += itf8_get(cp, &c->beta.offset);
+ cp += itf8_get(cp, &c->beta.nbits);
+
+ if (cp - data != size
+ || c->beta.nbits < 0 || c->beta.nbits > 8 * sizeof(int)) {
+ fprintf(stderr, "Malformed beta header stream\n");
+ free(c);
+ return NULL;
+ }
+
+ return c;
+}
+
+int cram_beta_encode_store(cram_codec *c, cram_block *b,
+ char *prefix, int version) {
+ int len = 0;
+
+ if (prefix) {
+ size_t l = strlen(prefix);
+ BLOCK_APPEND(b, prefix, l);
+ len += l;
+ }
+
+ len += itf8_put_blk(b, c->codec);
+ len += itf8_put_blk(b, itf8_size(c->e_beta.offset)
+ + itf8_size(c->e_beta.nbits)); // codec length
+ len += itf8_put_blk(b, c->e_beta.offset);
+ len += itf8_put_blk(b, c->e_beta.nbits);
+
+ return len;
+}
+
+int cram_beta_encode_int(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ int *syms = (int *)in;
+ int i, r = 0;
+
+ for (i = 0; i < in_size; i++)
+ r |= store_bits_MSB(c->out, syms[i] + c->e_beta.offset,
+ c->e_beta.nbits);
+
+ return r;
+}
+
+int cram_beta_encode_char(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ unsigned char *syms = (unsigned char *)in;
+ int i, r = 0;
+
+ for (i = 0; i < in_size; i++)
+ r |= store_bits_MSB(c->out, syms[i] + c->e_beta.offset,
+ c->e_beta.nbits);
+
+ return r;
+}
+
+void cram_beta_encode_free(cram_codec *c) {
+ if (c) free(c);
+}
+
+cram_codec *cram_beta_encode_init(cram_stats *st,
+ enum cram_external_type option,
+ void *dat,
+ int version) {
+ cram_codec *c;
+ int min_val, max_val, len = 0;
+
+ c = malloc(sizeof(*c));
+ if (!c)
+ return NULL;
+ c->codec = E_BETA;
+ c->free = cram_beta_encode_free;
+ if (option == E_INT)
+ c->encode = cram_beta_encode_int;
+ else
+ c->encode = cram_beta_encode_char;
+ c->store = cram_beta_encode_store;
+
+ if (dat) {
+ min_val = ((int *)dat)[0];
+ max_val = ((int *)dat)[1];
+ } else {
+ min_val = INT_MAX;
+ max_val = INT_MIN;
+ int i;
+ for (i = 0; i < MAX_STAT_VAL; i++) {
+ if (!st->freqs[i])
+ continue;
+ if (min_val > i)
+ min_val = i;
+ max_val = i;
+ }
+ if (st->h) {
+ khint_t k;
+
+ for (k = kh_begin(st->h); k != kh_end(st->h); k++) {
+ if (!kh_exist(st->h, k))
+ continue;
+
+ i = kh_key(st->h, k);
+ if (min_val > i)
+ min_val = i;
+ if (max_val < i)
+ max_val = i;
+ }
+ }
+ }
+
+ assert(max_val >= min_val);
+ c->e_beta.offset = -min_val;
+ max_val -= min_val;
+ while (max_val) {
+ len++;
+ max_val >>= 1;
+ }
+ c->e_beta.nbits = len;
+
+ return c;
+}
+
+/*
+ * ---------------------------------------------------------------------------
+ * SUBEXP
+ */
+int cram_subexp_decode(cram_slice *slice, cram_codec *c, cram_block *in, char *out, int *out_size) {
+ int32_t *out_i = (int32_t *)out;
+ int n, count;
+ int k = c->subexp.k;
+
+ for (count = 0, n = *out_size; count < n; count++) {
+ int i = 0, tail;
+ int val;
+
+ /* Get number of 1s */
+ //while (get_bit_MSB(in) == 1) i++;
+ i = get_one_bits_MSB(in);
+ if (i < 0 || cram_not_enough_bits(in, i > 0 ? i + k - 1 : k))
+ return -1;
+ /*
+ * Val is
+ * i > 0: 2^(k+i-1) + k+i-1 bits
+ * i = 0: k bits
+ */
+ if (i) {
+ tail = i + k-1;
+ val = 0;
+ while (tail) {
+ //val = val<<1; val |= get_bit_MSB(in);
+ GET_BIT_MSB(in, val);
+ tail--;
+ }
+ val += 1 << (i + k-1);
+ } else {
+ tail = k;
+ val = 0;
+ while (tail) {
+ //val = val<<1; val |= get_bit_MSB(in);
+ GET_BIT_MSB(in, val);
+ tail--;
+ }
+ }
+
+ out_i[count] = val - c->subexp.offset;
+ }
+
+ return 0;
+}
+
+void cram_subexp_decode_free(cram_codec *c) {
+ if (c)
+ free(c);
+}
+
+cram_codec *cram_subexp_decode_init(char *data, int size,
+ enum cram_external_type option,
+ int version) {
+ cram_codec *c;
+ char *cp = data;
+
+ if (!(c = malloc(sizeof(*c))))
+ return NULL;
+
+ c->codec = E_SUBEXP;
+ c->decode = cram_subexp_decode;
+ c->free = cram_subexp_decode_free;
+ c->subexp.k = -1;
+
+ cp += safe_itf8_get(cp, data + size, &c->subexp.offset);
+ cp += safe_itf8_get(cp, data + size, &c->subexp.k);
+
+ if (cp - data != size || c->subexp.k < 0) {
+ fprintf(stderr, "Malformed subexp header stream\n");
+ free(c);
+ return NULL;
+ }
+
+ return c;
+}
+
+/*
+ * ---------------------------------------------------------------------------
+ * GAMMA
+ */
+int cram_gamma_decode(cram_slice *slice, cram_codec *c, cram_block *in, char *out, int *out_size) {
+ int32_t *out_i = (int32_t *)out;
+ int i, n;
+
+ for (i = 0, n = *out_size; i < n; i++) {
+ int nz = 0;
+ int val;
+ //while (get_bit_MSB(in) == 0) nz++;
+ nz = get_zero_bits_MSB(in);
+ if (cram_not_enough_bits(in, nz))
+ return -1;
+ val = 1;
+ while (nz > 0) {
+ //val <<= 1; val |= get_bit_MSB(in);
+ GET_BIT_MSB(in, val);
+ nz--;
+ }
+
+ out_i[i] = val - c->gamma.offset;
+ }
+
+ return 0;
+}
+
+void cram_gamma_decode_free(cram_codec *c) {
+ if (c)
+ free(c);
+}
+
+cram_codec *cram_gamma_decode_init(char *data, int size,
+ enum cram_external_type option,
+ int version) {
+ cram_codec *c;
+ char *cp = data;
+
+ if (!(c = malloc(sizeof(*c))))
+ return NULL;
+
+ c->codec = E_GAMMA;
+ c->decode = cram_gamma_decode;
+ c->free = cram_gamma_decode_free;
+
+ cp += itf8_get(cp, &c->gamma.offset);
+
+ if (cp - data != size) {
+ fprintf(stderr, "Malformed gamma header stream\n");
+ free(c);
+ return NULL;
+ }
+
+ return c;
+}
+
+/*
+ * ---------------------------------------------------------------------------
+ * HUFFMAN
+ */
+
+static int code_sort(const void *vp1, const void *vp2) {
+ const cram_huffman_code *c1 = (const cram_huffman_code *)vp1;
+ const cram_huffman_code *c2 = (const cram_huffman_code *)vp2;
+
+ if (c1->len != c2->len)
+ return c1->len - c2->len;
+ else
+ return c1->symbol - c2->symbol;
+}
+
+void cram_huffman_decode_free(cram_codec *c) {
+ if (!c)
+ return;
+
+ if (c->huffman.codes)
+ free(c->huffman.codes);
+ free(c);
+}
+
+int cram_huffman_decode_null(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out, int *out_size) {
+ return -1;
+}
+
+int cram_huffman_decode_char0(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out, int *out_size) {
+ int i, n;
+
+ if (!out)
+ return 0;
+
+ /* Special case of 0 length codes */
+ for (i = 0, n = *out_size; i < n; i++) {
+ out[i] = c->huffman.codes[0].symbol;
+ }
+ return 0;
+}
+
+int cram_huffman_decode_char(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out, int *out_size) {
+ int i, n, ncodes = c->huffman.ncodes;
+ const cram_huffman_code * const codes = c->huffman.codes;
+
+ for (i = 0, n = *out_size; i < n; i++) {
+ int idx = 0;
+ int val = 0, len = 0, last_len = 0;
+
+ for (;;) {
+ int dlen = codes[idx].len - last_len;
+ if (cram_not_enough_bits(in, dlen))
+ return -1;
+
+ //val <<= dlen;
+ //val |= get_bits_MSB(in, dlen);
+ //last_len = (len += dlen);
+
+ last_len = (len += dlen);
+ for (; dlen; dlen--) GET_BIT_MSB(in, val);
+
+ idx = val - codes[idx].p;
+ if (idx >= ncodes || idx < 0)
+ return -1;
+
+ if (codes[idx].code == val && codes[idx].len == len) {
+ out[i] = codes[idx].symbol;
+ break;
+ }
+ }
+ }
+
+ return 0;
+}
+
+int cram_huffman_decode_int0(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out, int *out_size) {
+ int32_t *out_i = (int32_t *)out;
+ int i, n;
+ const cram_huffman_code * const codes = c->huffman.codes;
+
+ /* Special case of 0 length codes */
+ for (i = 0, n = *out_size; i < n; i++) {
+ out_i[i] = codes[0].symbol;
+ }
+ return 0;
+}
+
+int cram_huffman_decode_int(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out, int *out_size) {
+ int32_t *out_i = (int32_t *)out;
+ int i, n, ncodes = c->huffman.ncodes;
+ const cram_huffman_code * const codes = c->huffman.codes;
+
+ for (i = 0, n = *out_size; i < n; i++) {
+ int idx = 0;
+ int val = 0, len = 0, last_len = 0;
+
+ // Now one bit at a time for remaining checks
+ for (;;) {
+ int dlen = codes[idx].len - last_len;
+ if (cram_not_enough_bits(in, dlen))
+ return -1;
+
+ //val <<= dlen;
+ //val |= get_bits_MSB(in, dlen);
+ //last_len = (len += dlen);
+
+ last_len = (len += dlen);
+ for (; dlen; dlen--) GET_BIT_MSB(in, val);
+
+ idx = val - codes[idx].p;
+ if (idx >= ncodes || idx < 0)
+ return -1;
+
+ if (codes[idx].code == val && codes[idx].len == len) {
+ out_i[i] = codes[idx].symbol;
+ break;
+ }
+ }
+ }
+
+ return 0;
+}
+
+/*
+ * Initialises a huffman decoder from an encoding data stream.
+ */
+cram_codec *cram_huffman_decode_init(char *data, int size,
+ enum cram_external_type option,
+ int version) {
+ int32_t ncodes = 0, i, j;
+ char *cp = data, *data_end = &data[size];
+ cram_codec *h;
+ cram_huffman_code *codes;
+ int32_t val, last_len, max_len = 0;
+ int l;
+
+ cp += safe_itf8_get(cp, data_end, &ncodes);
+ h = calloc(1, sizeof(*h));
+ if (!h)
+ return NULL;
+
+ h->codec = E_HUFFMAN;
+ h->free = cram_huffman_decode_free;
+
+ h->huffman.ncodes = ncodes;
+ codes = h->huffman.codes = malloc(ncodes * sizeof(*codes));
+ if (!codes) {
+ free(h);
+ return NULL;
+ }
+
+ /* Read symbols and bit-lengths */
+ for (i = 0, l = 1; i < ncodes && l > 0; i++, cp += l) {
+ l = safe_itf8_get(cp, data_end, &codes[i].symbol);
+ }
+
+ if (l < 1) {
+ fprintf(stderr, "Malformed huffman header stream\n");
+ free(h);
+ return NULL;
+ }
+ cp += safe_itf8_get(cp, data_end, &i);
+ if (i != ncodes) {
+ fprintf(stderr, "Malformed huffman header stream\n");
+ free(h);
+ return NULL;
+ }
+
+ if (ncodes == 0) {
+ /* NULL huffman stream. Ensure it returns an error if
+ anything tries to use it. */
+ h->decode = cram_huffman_decode_null;
+ return h;
+ }
+
+ for (i = 0, l = 1; i < ncodes; i++, cp += l) {
+ l = safe_itf8_get(cp, data_end, &codes[i].len);
+ if (l < 1)
+ break;
+ if (max_len < codes[i].len)
+ max_len = codes[i].len;
+ }
+ if (l < 1 || cp - data != size || max_len >= ncodes) {
+ fprintf(stderr, "Malformed huffman header stream\n");
+ free(h);
+ return NULL;
+ }
+
+ /* Sort by bit length and then by symbol value */
+ qsort(codes, ncodes, sizeof(*codes), code_sort);
+
+ /* Assign canonical codes */
+ val = -1, last_len = 0;
+ for (i = 0; i < ncodes; i++) {
+ val++;
+ if (codes[i].len > last_len) {
+ while (codes[i].len > last_len) {
+ val <<= 1;
+ last_len++;
+ }
+ }
+ codes[i].code = val;
+ }
+
+ /*
+ * Compute the next starting point, offset by the i'th value.
+ * For example if codes 10, 11, 12, 13 are 30, 31, 32, 33 then
+ * codes[10..13].p = 30 - 10.
+ */
+ last_len = 0;
+ for (i = j = 0; i < ncodes; i++) {
+ if (codes[i].len > last_len) {
+ j = codes[i].code - i;
+ last_len = codes[i].len;
+ }
+ codes[i].p = j;
+ }
+
+// puts("==HUFF LEN==");
+// for (i = 0; i <= last_len+1; i++) {
+// printf("len %d=%d prefix %d\n", i, h->huffman.lengths[i], h->huffman.prefix[i]);
+// }
+// puts("===HUFFMAN CODES===");
+// for (i = 0; i < ncodes; i++) {
+// int j;
+// printf("%d: %d %d %d ", i, codes[i].symbol, codes[i].len, codes[i].code);
+// j = codes[i].len;
+// while (j) {
+// putchar(codes[i].code & (1 << --j) ? '1' : '0');
+// }
+// printf(" %d\n", codes[i].code);
+// }
+
+ if (option == E_BYTE || option == E_BYTE_ARRAY) {
+ if (h->huffman.codes[0].len == 0)
+ h->decode = cram_huffman_decode_char0;
+ else
+ h->decode = cram_huffman_decode_char;
+ } else if (option == E_BYTE_ARRAY_BLOCK) {
+ abort();
+ } else {
+ if (h->huffman.codes[0].len == 0)
+ h->decode = cram_huffman_decode_int0;
+ else
+ h->decode = cram_huffman_decode_int;
+ }
+
+ return (cram_codec *)h;
+}
+
+int cram_huffman_encode_char0(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ return 0;
+}
+
+int cram_huffman_encode_char(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ int i, code, len, r = 0;
+ unsigned char *syms = (unsigned char *)in;
+
+ while (in_size--) {
+ int sym = *syms++;
+ if (sym >= -1 && sym < MAX_HUFF) {
+ i = c->e_huffman.val2code[sym+1];
+ assert(c->e_huffman.codes[i].symbol == sym);
+ code = c->e_huffman.codes[i].code;
+ len = c->e_huffman.codes[i].len;
+ } else {
+ /* Slow - use a lookup table for when sym < MAX_HUFF? */
+ for (i = 0; i < c->e_huffman.nvals; i++) {
+ if (c->e_huffman.codes[i].symbol == sym)
+ break;
+ }
+ if (i == c->e_huffman.nvals)
+ return -1;
+
+ code = c->e_huffman.codes[i].code;
+ len = c->e_huffman.codes[i].len;
+ }
+
+ r |= store_bits_MSB(c->out, code, len);
+ }
+
+ return r;
+}
+
+int cram_huffman_encode_int0(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ return 0;
+}
+
+int cram_huffman_encode_int(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ int i, code, len, r = 0;
+ int *syms = (int *)in;
+
+ while (in_size--) {
+ int sym = *syms++;
+
+ if (sym >= -1 && sym < MAX_HUFF) {
+ i = c->e_huffman.val2code[sym+1];
+ assert(c->e_huffman.codes[i].symbol == sym);
+ code = c->e_huffman.codes[i].code;
+ len = c->e_huffman.codes[i].len;
+ } else {
+ /* Slow - use a lookup table for when sym < MAX_HUFFMAN_SYM? */
+ for (i = 0; i < c->e_huffman.nvals; i++) {
+ if (c->e_huffman.codes[i].symbol == sym)
+ break;
+ }
+ if (i == c->e_huffman.nvals)
+ return -1;
+
+ code = c->e_huffman.codes[i].code;
+ len = c->e_huffman.codes[i].len;
+ }
+
+ r |= store_bits_MSB(c->out, code, len);
+ }
+
+ return r;
+}
+
+void cram_huffman_encode_free(cram_codec *c) {
+ if (!c)
+ return;
+
+ if (c->e_huffman.codes)
+ free(c->e_huffman.codes);
+ free(c);
+}
+
+/*
+ * Encodes a huffman tree.
+ * Returns number of bytes written.
+ */
+int cram_huffman_encode_store(cram_codec *c, cram_block *b, char *prefix,
+ int version) {
+ int i, len = 0;
+ cram_huffman_code *codes = c->e_huffman.codes;
+ /*
+ * Up to code length 127 means 2.5e+26 bytes of data required (worst
+ * case huffman tree needs symbols with freqs matching the Fibonacci
+ * series). So guaranteed 1 byte per code.
+ *
+ * Symbols themselves could be 5 bytes (eg -1 is 5 bytes in itf8).
+ *
+ * Therefore 6*ncodes + 5 + 5 + 1 + 5 is max memory
+ */
+ char *tmp = malloc(6*c->e_huffman.nvals+16);
+ char *tp = tmp;
+
+ if (!tmp)
+ return -1;
+
+ if (prefix) {
+ size_t l = strlen(prefix);
+ BLOCK_APPEND(b, prefix, l);
+ len += l;
+ }
+
+ tp += itf8_put(tp, c->e_huffman.nvals);
+ for (i = 0; i < c->e_huffman.nvals; i++) {
+ tp += itf8_put(tp, codes[i].symbol);
+ }
+
+ tp += itf8_put(tp, c->e_huffman.nvals);
+ for (i = 0; i < c->e_huffman.nvals; i++) {
+ tp += itf8_put(tp, codes[i].len);
+ }
+
+ len += itf8_put_blk(b, c->codec);
+ len += itf8_put_blk(b, tp-tmp);
+ BLOCK_APPEND(b, tmp, tp-tmp);
+ len += tp-tmp;
+
+ free(tmp);
+
+ return len;
+}
+
+cram_codec *cram_huffman_encode_init(cram_stats *st,
+ enum cram_external_type option,
+ void *dat,
+ int version) {
+ int *vals = NULL, *freqs = NULL, vals_alloc = 0, *lens, code, len;
+ int nvals, i, ntot = 0, max_val = 0, min_val = INT_MAX, k;
+ cram_codec *c;
+ cram_huffman_code *codes;
+
+ c = malloc(sizeof(*c));
+ if (!c)
+ return NULL;
+ c->codec = E_HUFFMAN;
+
+ /* Count number of unique symbols */
+ for (nvals = i = 0; i < MAX_STAT_VAL; i++) {
+ if (!st->freqs[i])
+ continue;
+ if (nvals >= vals_alloc) {
+ vals_alloc = vals_alloc ? vals_alloc*2 : 1024;
+ vals = realloc(vals, vals_alloc * sizeof(int));
+ freqs = realloc(freqs, vals_alloc * sizeof(int));
+ if (!vals || !freqs) {
+ if (vals) free(vals);
+ if (freqs) free(freqs);
+ free(c);
+ return NULL;
+ }
+ }
+ vals[nvals] = i;
+ freqs[nvals] = st->freqs[i];
+ assert(st->freqs[i] > 0);
+ ntot += freqs[nvals];
+ if (max_val < i) max_val = i;
+ if (min_val > i) min_val = i;
+ nvals++;
+ }
+ if (st->h) {
+ khint_t k;
+
+ for (k = kh_begin(st->h); k != kh_end(st->h); k++) {
+ if (!kh_exist(st->h, k))
+ continue;
+ if (nvals >= vals_alloc) {
+ vals_alloc = vals_alloc ? vals_alloc*2 : 1024;
+ vals = realloc(vals, vals_alloc * sizeof(int));
+ freqs = realloc(freqs, vals_alloc * sizeof(int));
+ if (!vals || !freqs)
+ return NULL;
+ }
+ vals[nvals]= kh_key(st->h, k);
+ freqs[nvals] = kh_val(st->h, k);
+ assert(freqs[nvals] > 0);
+ ntot += freqs[nvals];
+ if (max_val < i) max_val = i;
+ if (min_val > i) min_val = i;
+ nvals++;
+ }
+ }
+
+ assert(nvals > 0);
+
+ freqs = realloc(freqs, 2*nvals*sizeof(*freqs));
+ lens = calloc(2*nvals, sizeof(*lens));
+ if (!lens || !freqs)
+ return NULL;
+
+ /* Inefficient, use pointers to form chain so we can insert and maintain
+ * a sorted list? This is currently O(nvals^2) complexity.
+ */
+ for (;;) {
+ int low1 = INT_MAX, low2 = INT_MAX;
+ int ind1 = 0, ind2 = 0;
+ for (i = 0; i < nvals; i++) {
+ if (freqs[i] < 0)
+ continue;
+ if (low1 > freqs[i])
+ low2 = low1, ind2 = ind1, low1 = freqs[i], ind1 = i;
+ else if (low2 > freqs[i])
+ low2 = freqs[i], ind2 = i;
+ }
+ if (low2 == INT_MAX)
+ break;
+
+ freqs[nvals] = low1 + low2;
+ lens[ind1] = nvals;
+ lens[ind2] = nvals;
+ freqs[ind1] *= -1;
+ freqs[ind2] *= -1;
+ nvals++;
+ }
+ nvals = nvals/2+1;
+
+ /* Assign lengths */
+ for (i = 0; i < nvals; i++) {
+ int code_len = 0;
+ for (k = lens[i]; k; k = lens[k])
+ code_len++;
+ lens[i] = code_len;
+ freqs[i] *= -1;
+ //fprintf(stderr, "%d / %d => %d\n", vals[i], freqs[i], lens[i]);
+ }
+
+
+ /* Sort, need in a struct */
+ if (!(codes = malloc(nvals * sizeof(*codes))))
+ return NULL;
+ for (i = 0; i < nvals; i++) {
+ codes[i].symbol = vals[i];
+ codes[i].len = lens[i];
+ }
+ qsort(codes, nvals, sizeof(*codes), code_sort);
+
+ /*
+ * Generate canonical codes from lengths.
+ * Sort by length.
+ * Start with 0.
+ * Every new code of same length is +1.
+ * Every new code of new length is +1 then <<1 per extra length.
+ *
+ * /\
+ * a/\
+ * /\/\
+ * bcd/\
+ * ef
+ *
+ * a 1 0
+ * b 3 4 (0+1)<<2
+ * c 3 5
+ * d 3 6
+ * e 4 14 (6+1)<<1
+ * f 5 15
+ */
+ code = 0; len = codes[0].len;
+ for (i = 0; i < nvals; i++) {
+ while (len != codes[i].len) {
+ code<<=1;
+ len++;
+ }
+ codes[i].code = code++;
+
+ if (codes[i].symbol >= -1 && codes[i].symbol < MAX_HUFF)
+ c->e_huffman.val2code[codes[i].symbol+1] = i;
+
+ //fprintf(stderr, "sym %d, code %d, len %d\n",
+ // codes[i].symbol, codes[i].code, codes[i].len);
+ }
+
+ free(lens);
+ free(vals);
+ free(freqs);
+
+ c->e_huffman.codes = codes;
+ c->e_huffman.nvals = nvals;
+
+ c->free = cram_huffman_encode_free;
+ if (option == E_BYTE || option == E_BYTE_ARRAY) {
+ if (c->e_huffman.codes[0].len == 0)
+ c->encode = cram_huffman_encode_char0;
+ else
+ c->encode = cram_huffman_encode_char;
+ } else {
+ if (c->e_huffman.codes[0].len == 0)
+ c->encode = cram_huffman_encode_int0;
+ else
+ c->encode = cram_huffman_encode_int;
+ }
+ c->store = cram_huffman_encode_store;
+
+ return c;
+}
+
+/*
+ * ---------------------------------------------------------------------------
+ * BYTE_ARRAY_LEN
+ */
+int cram_byte_array_len_decode(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out,
+ int *out_size) {
+ /* Fetch length */
+ int32_t len = 0, one = 1;
+ int r;
+
+ r = c->byte_array_len.len_codec->decode(slice, c->byte_array_len.len_codec,
+ in, (char *)&len, &one);
+ //printf("ByteArray Len=%d\n", len);
+
+ if (!r && c->byte_array_len.val_codec && len >= 0) {
+ r = c->byte_array_len.val_codec->decode(slice,
+ c->byte_array_len.val_codec,
+ in, out, &len);
+ } else {
+ return -1;
+ }
+
+ *out_size = len;
+
+ return r;
+}
+
+void cram_byte_array_len_decode_free(cram_codec *c) {
+ if (!c) return;
+
+ if (c->byte_array_len.len_codec)
+ c->byte_array_len.len_codec->free(c->byte_array_len.len_codec);
+
+ if (c->byte_array_len.val_codec)
+ c->byte_array_len.val_codec->free(c->byte_array_len.val_codec);
+
+ free(c);
+}
+
+cram_codec *cram_byte_array_len_decode_init(char *data, int size,
+ enum cram_external_type option,
+ int version) {
+ cram_codec *c;
+ char *cp = data;
+ char *endp = data + size;
+ int32_t encoding = 0;
+ int32_t sub_size = -1;
+
+ if (!(c = malloc(sizeof(*c))))
+ return NULL;
+
+ c->codec = E_BYTE_ARRAY_LEN;
+ c->decode = cram_byte_array_len_decode;
+ c->free = cram_byte_array_len_decode_free;
+
+ cp += safe_itf8_get(cp, endp, &encoding);
+ cp += safe_itf8_get(cp, endp, &sub_size);
+ if (sub_size < 0 || endp - cp < sub_size)
+ goto malformed;
+ c->byte_array_len.len_codec = cram_decoder_init(encoding, cp, sub_size,
+ E_INT, version);
+ if (c->byte_array_len.len_codec == NULL)
+ goto no_codec;
+ cp += sub_size;
+
+ sub_size = -1;
+ cp += safe_itf8_get(cp, endp, &encoding);
+ cp += safe_itf8_get(cp, endp, &sub_size);
+ if (sub_size < 0 || endp - cp < sub_size)
+ goto malformed;
+ c->byte_array_len.val_codec = cram_decoder_init(encoding, cp, sub_size,
+ option, version);
+ if (c->byte_array_len.val_codec == NULL)
+ goto no_codec;
+ cp += sub_size;
+
+ if (cp - data != size)
+ goto malformed;
+
+ return c;
+
+ malformed:
+ fprintf(stderr, "Malformed byte_array_len header stream\n");
+ no_codec:
+ free(c);
+ return NULL;
+}
+
+int cram_byte_array_len_encode(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ int32_t i32 = in_size;
+ int r = 0;
+
+ r |= c->e_byte_array_len.len_codec->encode(slice,
+ c->e_byte_array_len.len_codec,
+ (char *)&i32, 1);
+ r |= c->e_byte_array_len.val_codec->encode(slice,
+ c->e_byte_array_len.val_codec,
+ in, in_size);
+ return r;
+}
+
+void cram_byte_array_len_encode_free(cram_codec *c) {
+ if (!c)
+ return;
+
+ if (c->e_byte_array_len.len_codec)
+ c->e_byte_array_len.len_codec->free(c->e_byte_array_len.len_codec);
+
+ if (c->e_byte_array_len.val_codec)
+ c->e_byte_array_len.val_codec->free(c->e_byte_array_len.val_codec);
+
+ free(c);
+}
+
+int cram_byte_array_len_encode_store(cram_codec *c, cram_block *b,
+ char *prefix, int version) {
+ int len = 0, len2, len3;
+ cram_codec *tc;
+ cram_block *b_len, *b_val;
+
+ if (prefix) {
+ size_t l = strlen(prefix);
+ BLOCK_APPEND(b, prefix, l);
+ len += l;
+ }
+
+ tc = c->e_byte_array_len.len_codec;
+ b_len = cram_new_block(0, 0);
+ len2 = tc->store(tc, b_len, NULL, version);
+
+ tc = c->e_byte_array_len.val_codec;
+ b_val = cram_new_block(0, 0);
+ len3 = tc->store(tc, b_val, NULL, version);
+
+ len += itf8_put_blk(b, c->codec);
+ len += itf8_put_blk(b, len2+len3);
+ BLOCK_APPEND(b, BLOCK_DATA(b_len), BLOCK_SIZE(b_len));
+ BLOCK_APPEND(b, BLOCK_DATA(b_val), BLOCK_SIZE(b_val));
+
+ cram_free_block(b_len);
+ cram_free_block(b_val);
+
+ return len + len2 + len3;
+}
+
+cram_codec *cram_byte_array_len_encode_init(cram_stats *st,
+ enum cram_external_type option,
+ void *dat,
+ int version) {
+ cram_codec *c;
+ cram_byte_array_len_encoder *e = (cram_byte_array_len_encoder *)dat;
+
+ c = malloc(sizeof(*c));
+ if (!c)
+ return NULL;
+ c->codec = E_BYTE_ARRAY_LEN;
+ c->free = cram_byte_array_len_encode_free;
+ c->encode = cram_byte_array_len_encode;
+ c->store = cram_byte_array_len_encode_store;
+
+ c->e_byte_array_len.len_codec = cram_encoder_init(e->len_encoding,
+ NULL, E_INT,
+ e->len_dat,
+ version);
+ c->e_byte_array_len.val_codec = cram_encoder_init(e->val_encoding,
+ NULL, E_BYTE_ARRAY,
+ e->val_dat,
+ version);
+
+ return c;
+}
+
+/*
+ * ---------------------------------------------------------------------------
+ * BYTE_ARRAY_STOP
+ */
+static int cram_byte_array_stop_decode_char(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out,
+ int *out_size) {
+ cram_block *b = NULL;
+ char *cp, ch;
+
+ b = cram_get_block_by_id(slice, c->byte_array_stop.content_id);
+ if (!b)
+ return *out_size?-1:0;
+
+ if (b->idx >= b->uncomp_size)
+ return -1;
+
+ cp = (char *)b->data + b->idx;
+ if (out) {
+ while ((ch = *cp) != (char)c->byte_array_stop.stop) {
+ if (cp - (char *)b->data >= b->uncomp_size)
+ return -1;
+ *out++ = ch;
+ cp++;
+ }
+ } else {
+ // Consume input, but produce no output
+ while ((ch = *cp) != (char)c->byte_array_stop.stop) {
+ if (cp - (char *)b->data >= b->uncomp_size)
+ return -1;
+ cp++;
+ }
+ }
+
+ *out_size = cp - (char *)(b->data + b->idx);
+ b->idx = cp - (char *)b->data + 1;
+
+ return 0;
+}
+
+int cram_byte_array_stop_decode_block(cram_slice *slice, cram_codec *c,
+ cram_block *in, char *out_,
+ int *out_size) {
+ cram_block *b;
+ cram_block *out = (cram_block *)out_;
+ char *cp, *out_cp, *cp_end;
+ char stop;
+
+ b = cram_get_block_by_id(slice, c->byte_array_stop.content_id);
+ if (!b)
+ return *out_size?-1:0;
+
+ if (b->idx >= b->uncomp_size)
+ return -1;
+ cp = (char *)b->data + b->idx;
+ cp_end = (char *)b->data + b->uncomp_size;
+ out_cp = (char *)BLOCK_END(out);
+
+ stop = c->byte_array_stop.stop;
+ if (cp_end - cp < out->alloc - out->byte) {
+ while (cp != cp_end && *cp != stop)
+ *out_cp++ = *cp++;
+ BLOCK_SIZE(out) = out_cp - (char *)BLOCK_DATA(out);
+ } else {
+ char *cp_start;
+ for (cp_start = cp; cp != cp_end && *cp != stop; cp++)
+ ;
+ BLOCK_APPEND(out, cp_start, cp - cp_start);
+ BLOCK_GROW(out, cp - cp_start);
+ }
+
+ *out_size = cp - (char *)(b->data + b->idx);
+ b->idx = cp - (char *)b->data + 1;
+
+ return 0;
+}
+
+void cram_byte_array_stop_decode_free(cram_codec *c) {
+ if (!c) return;
+
+ free(c);
+}
+
+cram_codec *cram_byte_array_stop_decode_init(char *data, int size,
+ enum cram_external_type option,
+ int version) {
+ cram_codec *c;
+ unsigned char *cp = (unsigned char *)data;
+
+ if (!(c = malloc(sizeof(*c))))
+ return NULL;
+
+ c->codec = E_BYTE_ARRAY_STOP;
+ switch (option) {
+ case E_BYTE_ARRAY_BLOCK:
+ c->decode = cram_byte_array_stop_decode_block;
+ break;
+ case E_BYTE_ARRAY:
+ c->decode = cram_byte_array_stop_decode_char;
+ break;
+ default:
+ fprintf(stderr, "byte_array_stop codec only supports BYTE_ARRAYs.\n");
+ free(c);
+ return NULL;
+ }
+ c->free = cram_byte_array_stop_decode_free;
+
+ c->byte_array_stop.stop = *cp++;
+ if (CRAM_MAJOR_VERS(version) == 1) {
+ c->byte_array_stop.content_id = cp[0] + (cp[1]<<8) + (cp[2]<<16)
+ + (cp[3]<<24);
+ cp += 4;
+ } else {
+ cp += itf8_get(cp, &c->byte_array_stop.content_id);
+ }
+
+ if ((char *)cp - data != size) {
+ fprintf(stderr, "Malformed byte_array_stop header stream\n");
+ free(c);
+ return NULL;
+ }
+
+ return c;
+}
+
+int cram_byte_array_stop_encode(cram_slice *slice, cram_codec *c,
+ char *in, int in_size) {
+ BLOCK_APPEND(c->out, in, in_size);
+ BLOCK_APPEND_CHAR(c->out, c->e_byte_array_stop.stop);
+ return 0;
+}
+
+void cram_byte_array_stop_encode_free(cram_codec *c) {
+ if (!c)
+ return;
+ free(c);
+}
+
+int cram_byte_array_stop_encode_store(cram_codec *c, cram_block *b,
+ char *prefix, int version) {
+ int len = 0;
+ char buf[20], *cp = buf;
+
+ if (prefix) {
+ size_t l = strlen(prefix);
+ BLOCK_APPEND(b, prefix, l);
+ len += l;
+ }
+
+ cp += itf8_put(cp, c->codec);
+
+ if (CRAM_MAJOR_VERS(version) == 1) {
+ cp += itf8_put(cp, 5);
+ *cp++ = c->e_byte_array_stop.stop;
+ *cp++ = (c->e_byte_array_stop.content_id >> 0) & 0xff;
+ *cp++ = (c->e_byte_array_stop.content_id >> 8) & 0xff;
+ *cp++ = (c->e_byte_array_stop.content_id >> 16) & 0xff;
+ *cp++ = (c->e_byte_array_stop.content_id >> 24) & 0xff;
+ } else {
+ cp += itf8_put(cp, 1 + itf8_size(c->e_byte_array_stop.content_id));
+ *cp++ = c->e_byte_array_stop.stop;
+ cp += itf8_put(cp, c->e_byte_array_stop.content_id);
+ }
+
+ BLOCK_APPEND(b, buf, cp-buf);
+ len += cp-buf;
+
+ return len;
+}
+
+cram_codec *cram_byte_array_stop_encode_init(cram_stats *st,
+ enum cram_external_type option,
+ void *dat,
+ int version) {
+ cram_codec *c;
+
+ c = malloc(sizeof(*c));
+ if (!c)
+ return NULL;
+ c->codec = E_BYTE_ARRAY_STOP;
+ c->free = cram_byte_array_stop_encode_free;
+ c->encode = cram_byte_array_stop_encode;
+ c->store = cram_byte_array_stop_encode_store;
+
+ c->e_byte_array_stop.stop = ((int *)dat)[0];
+ c->e_byte_array_stop.content_id = ((int *)dat)[1];
+
+ return c;
+}
+
+/*
+ * ---------------------------------------------------------------------------
+ */
+
+const char *cram_encoding2str(enum cram_encoding t) {
+ switch (t) {
+ case E_NULL: return "NULL";
+ case E_EXTERNAL: return "EXTERNAL";
+ case E_GOLOMB: return "GOLOMB";
+ case E_HUFFMAN: return "HUFFMAN";
+ case E_BYTE_ARRAY_LEN: return "BYTE_ARRAY_LEN";
+ case E_BYTE_ARRAY_STOP: return "BYTE_ARRAY_STOP";
+ case E_BETA: return "BETA";
+ case E_SUBEXP: return "SUBEXP";
+ case E_GOLOMB_RICE: return "GOLOMB_RICE";
+ case E_GAMMA: return "GAMMA";
+ case E_NUM_CODECS:
+ default: return "?";
+ }
+}
+
+static cram_codec *(*decode_init[])(char *data,
+ int size,
+ enum cram_external_type option,
+ int version) = {
+ NULL,
+ cram_external_decode_init,
+ NULL,
+ cram_huffman_decode_init,
+ cram_byte_array_len_decode_init,
+ cram_byte_array_stop_decode_init,
+ cram_beta_decode_init,
+ cram_subexp_decode_init,
+ NULL,
+ cram_gamma_decode_init,
+};
+
+cram_codec *cram_decoder_init(enum cram_encoding codec,
+ char *data, int size,
+ enum cram_external_type option,
+ int version) {
+ if (codec >= E_NULL && codec < E_NUM_CODECS && decode_init[codec]) {
+ return decode_init[codec](data, size, option, version);
+ } else {
+ fprintf(stderr, "Unimplemented codec of type %s\n", cram_encoding2str(codec));
+ return NULL;
+ }
+}
+
+static cram_codec *(*encode_init[])(cram_stats *stx,
+ enum cram_external_type option,
+ void *opt,
+ int version) = {
+ NULL,
+ cram_external_encode_init,
+ NULL,
+ cram_huffman_encode_init,
+ cram_byte_array_len_encode_init,
+ cram_byte_array_stop_encode_init,
+ cram_beta_encode_init,
+ NULL, //cram_subexp_encode_init,
+ NULL,
+ NULL, //cram_gamma_encode_init,
+};
+
+cram_codec *cram_encoder_init(enum cram_encoding codec,
+ cram_stats *st,
+ enum cram_external_type option,
+ void *dat,
+ int version) {
+ if (st && !st->nvals)
+ return NULL;
+
+ if (encode_init[codec]) {
+ cram_codec *r;
+ if ((r = encode_init[codec](st, option, dat, version)))
+ r->out = NULL;
+ return r;
+ } else {
+ fprintf(stderr, "Unimplemented codec of type %s\n", cram_encoding2str(codec));
+ abort();
+ }
+}
+
+/*
+ * Returns the content_id used by this codec, also in id2 if byte_array_len.
+ * Returns -1 for the CORE block and -2 for unneeded.
+ * id2 is only filled out for BYTE_ARRAY_LEN which uses 2 codecs.
+ */
+int cram_codec_to_id(cram_codec *c, int *id2) {
+ int bnum1, bnum2 = -2;
+
+ switch (c->codec) {
+ case E_HUFFMAN:
+ bnum1 = c->huffman.ncodes == 1 ? -2 : -1;
+ break;
+ case E_GOLOMB:
+ case E_BETA:
+ case E_SUBEXP:
+ case E_GOLOMB_RICE:
+ case E_GAMMA:
+ bnum1 = -1;
+ break;
+ case E_EXTERNAL:
+ bnum1 = c->external.content_id;
+ break;
+ case E_BYTE_ARRAY_LEN:
+ bnum1 = cram_codec_to_id(c->byte_array_len.len_codec, NULL);
+ bnum2 = cram_codec_to_id(c->byte_array_len.val_codec, NULL);
+ break;
+ case E_BYTE_ARRAY_STOP:
+ bnum1 = c->byte_array_stop.content_id;
+ break;
+ case E_NULL:
+ bnum1 = -2;
+ break;
+ default:
+ fprintf(stderr, "Unknown codec type %d\n", c->codec);
+ bnum1 = -1;
+ }
+
+ if (id2)
+ *id2 = bnum2;
+ return bnum1;
+}
+
+
+/*
+ * cram_codec structures are specialised for decoding or encoding.
+ * Unfortunately this makes turning a decoder into an encoder (such as
+ * when transcoding files) problematic.
+ *
+ * This function converts a cram decoder codec into an encoder version
+ * in-place (ie it modifiers the codec itself).
+ *
+ * Returns 0 on success;
+ * -1 on failure.
+ */
+int cram_codec_decoder2encoder(cram_fd *fd, cram_codec *c) {
+ int j;
+
+ switch (c->codec) {
+ case E_EXTERNAL:
+ // shares struct with decode
+ c->free = cram_external_encode_free;
+ c->store = cram_external_encode_store;
+ if (c->decode == cram_external_decode_int)
+ c->encode = cram_external_encode_int;
+ else if (c->decode == cram_external_decode_char)
+ c->encode = cram_external_encode_char;
+ else
+ return -1;
+ break;
+
+ case E_HUFFMAN: {
+ // New structure, so switch.
+ // FIXME: we huffman and e_huffman structs amended, we could
+ // unify this.
+ cram_codec *t = malloc(sizeof(*t));
+ t->codec = E_HUFFMAN;
+ t->free = cram_huffman_encode_free;
+ t->store = cram_huffman_encode_store;
+ t->e_huffman.codes = c->huffman.codes;
+ t->e_huffman.nvals = c->huffman.ncodes;
+ for (j = 0; j < t->e_huffman.nvals; j++) {
+ int32_t sym = t->e_huffman.codes[j].symbol;
+ if (sym >= -1 && sym < MAX_HUFF)
+ t->e_huffman.val2code[sym+1] = j;
+ }
+
+ if (c->decode == cram_huffman_decode_char0)
+ t->encode = cram_huffman_encode_char0;
+ else if (c->decode == cram_huffman_decode_char)
+ t->encode = cram_huffman_encode_char;
+ else if (c->decode == cram_huffman_decode_int0)
+ t->encode = cram_huffman_encode_int0;
+ else if (c->decode == cram_huffman_decode_int)
+ t->encode = cram_huffman_encode_int;
+ else {
+ free(t);
+ return -1;
+ }
+ *c = *t;
+ free(t);
+ break;
+ }
+
+ case E_BETA:
+ // shares struct with decode
+ c->free = cram_beta_encode_free;
+ c->store = cram_beta_encode_store;
+ if (c->decode == cram_beta_decode_int)
+ c->encode = cram_beta_encode_int;
+ else if (c->decode == cram_beta_decode_char)
+ c->encode = cram_beta_encode_char;
+ else
+ return -1;
+ break;
+
+ case E_BYTE_ARRAY_LEN: {
+ cram_codec *t = malloc(sizeof(*t));
+ t->codec = E_BYTE_ARRAY_LEN;
+ t->free = cram_byte_array_len_encode_free;
+ t->store = cram_byte_array_len_encode_store;
+ t->encode = cram_byte_array_len_encode;
+ t->e_byte_array_len.len_codec = c->byte_array_len.len_codec;
+ t->e_byte_array_len.val_codec = c->byte_array_len.val_codec;
+ if (cram_codec_decoder2encoder(fd, t->e_byte_array_len.len_codec) == -1 ||
+ cram_codec_decoder2encoder(fd, t->e_byte_array_len.val_codec) == -1) {
+ t->free(t);
+ return -1;
+ }
+
+ // {len,val}_{encoding,dat} are undefined, but unused.
+ // Leaving them unset here means we can test that assertion.
+ *c = *t;
+ free(t);
+ break;
+ }
+
+ case E_BYTE_ARRAY_STOP:
+ // shares struct with decode
+ c->free = cram_byte_array_stop_encode_free;
+ c->store = cram_byte_array_stop_encode_store;
+ c->encode = cram_byte_array_stop_encode;
+ break;
+
+ default:
+ return -1;
+ }
+
+ return 0;
+}
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _CRAM_ENCODINGS_H_
+#define _CRAM_ENCODINGS_H_
+
+#include <inttypes.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+struct cram_codec;
+
+/*
+ * Slow but simple huffman decoder to start with.
+ * Read a bit at a time, keeping track of {length, value}
+ * eg. 1 1 0 1 => {1,1}, {2,3}, {3,6}, {4,13}
+ *
+ * Keep track of this through the huffman code table.
+ * For fast scanning we have an index of where the first code of length X
+ * appears.
+ */
+typedef struct {
+ int32_t symbol;
+ int32_t p; // next code start value, minus index to codes[]
+ int32_t code;
+ int32_t len;
+} cram_huffman_code;
+
+typedef struct {
+ int ncodes;
+ cram_huffman_code *codes;
+} cram_huffman_decoder;
+
+#define MAX_HUFF 128
+typedef struct {
+ cram_huffman_code *codes;
+ int nvals;
+ int val2code[MAX_HUFF+1]; // value to code lookup for small values
+} cram_huffman_encoder;
+
+typedef struct {
+ int32_t offset;
+ int32_t nbits;
+} cram_beta_decoder;
+
+typedef struct {
+ int32_t offset;
+} cram_gamma_decoder;
+
+typedef struct {
+ int32_t offset;
+ int32_t k;
+} cram_subexp_decoder;
+
+typedef struct {
+ int32_t content_id;
+ enum cram_external_type type;
+} cram_external_decoder;
+
+typedef struct {
+ struct cram_codec *len_codec;
+ struct cram_codec *val_codec;
+} cram_byte_array_len_decoder;
+
+typedef struct {
+ unsigned char stop;
+ int32_t content_id;
+} cram_byte_array_stop_decoder;
+
+typedef struct {
+ enum cram_encoding len_encoding;
+ enum cram_encoding val_encoding;
+ void *len_dat;
+ void *val_dat;
+ struct cram_codec *len_codec;
+ struct cram_codec *val_codec;
+} cram_byte_array_len_encoder;
+
+/*
+ * A generic codec structure.
+ */
+typedef struct cram_codec {
+ enum cram_encoding codec;
+ cram_block *out;
+ void (*free)(struct cram_codec *codec);
+ int (*decode)(cram_slice *slice, struct cram_codec *codec,
+ cram_block *in, char *out, int *out_size);
+ int (*encode)(cram_slice *slice, struct cram_codec *codec,
+ char *in, int in_size);
+ int (*store)(struct cram_codec *codec, cram_block *b, char *prefix,
+ int version);
+ union {
+ cram_huffman_decoder huffman;
+ cram_external_decoder external;
+ cram_beta_decoder beta;
+ cram_gamma_decoder gamma;
+ cram_subexp_decoder subexp;
+ cram_byte_array_len_decoder byte_array_len;
+ cram_byte_array_stop_decoder byte_array_stop;
+
+ cram_huffman_encoder e_huffman;
+ cram_external_decoder e_external;
+ cram_byte_array_stop_decoder e_byte_array_stop;
+ cram_byte_array_len_encoder e_byte_array_len;
+ cram_beta_decoder e_beta;
+ };
+} cram_codec;
+
+const char *cram_encoding2str(enum cram_encoding t);
+
+cram_codec *cram_decoder_init(enum cram_encoding codec, char *data, int size,
+ enum cram_external_type option,
+ int version);
+cram_codec *cram_encoder_init(enum cram_encoding codec, cram_stats *st,
+ enum cram_external_type option, void *dat,
+ int version);
+
+//int cram_decode(void *codes, char *in, int in_size, char *out, int *out_size);
+//void cram_decoder_free(void *codes);
+
+//#define GET_BIT_MSB(b,v) (void)(v<<=1, v|=(b->data[b->byte] >> b->bit)&1, (--b->bit == -1) && (b->bit = 7, b->byte++))
+
+#define GET_BIT_MSB(b,v) (void)(v<<=1, v|=(b->data[b->byte] >> b->bit)&1, b->byte += (--b->bit<0), b->bit&=7)
+
+/*
+ * Check that enough bits are left in a block to satisy a bit-based decoder.
+ * Return 0 if there are enough
+ * 1 if not.
+ */
+
+static inline int cram_not_enough_bits(cram_block *blk, int nbits) {
+ if (nbits < 0 ||
+ (blk->byte >= blk->uncomp_size && nbits > 0) ||
+ (blk->uncomp_size - blk->byte <= INT32_MAX / 8 + 1 &&
+ (blk->uncomp_size - blk->byte) * 8 + blk->bit - 7 < nbits)) {
+ return 1;
+ }
+ return 0;
+}
+
+/*
+ * Returns the content_id used by this codec, also in id2 if byte_array_len.
+ * Returns -1 for the CORE block and -2 for unneeded.
+ * id2 is only filled out for BYTE_ARRAY_LEN which uses 2 codecs.
+ */
+int cram_codec_to_id(cram_codec *c, int *id2);
+
+/*
+ * cram_codec structures are specialised for decoding or encoding.
+ * Unfortunately this makes turning a decoder into an encoder (such as
+ * when transcoding files) problematic.
+ *
+ * This function converts a cram decoder codec into an encoder version
+ * in-place (ie it modifiers the codec itself).
+ *
+ * Returns 0 on success;
+ * -1 on failure.
+ */
+int cram_codec_decoder2encoder(cram_fd *fd, cram_codec *c);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _CRAM_ENCODINGS_H_ */
--- /dev/null
+/*
+Copyright (c) 2012-2014 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+ * - In-memory decoding of CRAM data structures.
+ * - Iterator for reading CRAM record by record.
+ */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <errno.h>
+#include <assert.h>
+#include <stdlib.h>
+#include <string.h>
+#include <zlib.h>
+#include <sys/types.h>
+#include <sys/stat.h>
+#include <math.h>
+#include <ctype.h>
+
+#include "cram/cram.h"
+#include "cram/os.h"
+#include "htslib/hts.h"
+
+//Whether CIGAR has just M or uses = and X to indicate match and mismatch
+//#define USE_X
+
+/* ----------------------------------------------------------------------
+ * CRAM compression headers
+ */
+
+/*
+ * Decodes the Tag Dictionary record in the preservation map
+ * Updates the cram compression header.
+ *
+ * Returns number of bytes decoded on success
+ * -1 on failure
+ */
+int cram_decode_TD(char *cp, const char *endp, cram_block_compression_hdr *h) {
+ char *op = cp;
+ unsigned char *dat;
+ cram_block *b;
+ int32_t blk_size = 0;
+ int nTL, i, sz;
+
+ if (!(b = cram_new_block(0, 0)))
+ return -1;
+
+ /* Decode */
+ cp += safe_itf8_get(cp, endp, &blk_size);
+ if (!blk_size) {
+ h->nTL = 0;
+ h->TL = NULL;
+ cram_free_block(b);
+ return cp - op;
+ }
+
+ if (blk_size < 0 || endp - cp < blk_size) {
+ cram_free_block(b);
+ return -1;
+ }
+
+ BLOCK_APPEND(b, cp, blk_size);
+ cp += blk_size;
+ sz = cp - op;
+ // Force nul termination if missing
+ if (BLOCK_DATA(b)[BLOCK_SIZE(b)-1])
+ BLOCK_APPEND_CHAR(b, '\0');
+
+ /* Set up TL lookup table */
+ dat = BLOCK_DATA(b);
+
+ // Count
+ for (nTL = i = 0; i < BLOCK_SIZE(b); i++) {
+ nTL++;
+ while (dat[i])
+ i++;
+ }
+
+ // Copy
+ h->nTL = nTL;
+ if (!(h->TL = calloc(h->nTL, sizeof(unsigned char *)))) {
+ cram_free_block(b);
+ return -1;
+ }
+ for (nTL = i = 0; i < BLOCK_SIZE(b); i++) {
+ h->TL[nTL++] = &dat[i];
+ while (dat[i])
+ i++;
+ }
+ h->TD_blk = b;
+
+ return sz;
+}
+
+/*
+ * Decodes a CRAM block compression header.
+ * Returns header ptr on success
+ * NULL on failure
+ */
+cram_block_compression_hdr *cram_decode_compression_header(cram_fd *fd,
+ cram_block *b) {
+ char *cp, *endp, *cp_copy;
+ cram_block_compression_hdr *hdr = calloc(1, sizeof(*hdr));
+ int i;
+ int32_t map_size = 0, map_count = 0;
+
+ if (!hdr)
+ return NULL;
+
+ if (b->method != RAW) {
+ if (cram_uncompress_block(b)) {
+ free(hdr);
+ return NULL;
+ }
+ }
+
+ cp = (char *)b->data;
+ endp = cp + b->uncomp_size;
+
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ cp += safe_itf8_get(cp, endp, &hdr->ref_seq_id);
+ cp += safe_itf8_get(cp, endp, &hdr->ref_seq_start);
+ cp += safe_itf8_get(cp, endp, &hdr->ref_seq_span);
+ cp += safe_itf8_get(cp, endp, &hdr->num_records);
+ cp += safe_itf8_get(cp, endp, &hdr->num_landmarks);
+ if (!(hdr->landmark = malloc(hdr->num_landmarks * sizeof(int32_t)))) {
+ free(hdr);
+ return NULL;
+ }
+ for (i = 0; i < hdr->num_landmarks; i++) {
+ cp += safe_itf8_get(cp, endp, &hdr->landmark[i]);
+ }
+ }
+
+ hdr->preservation_map = kh_init(map);
+
+ memset(hdr->rec_encoding_map, 0,
+ CRAM_MAP_HASH * sizeof(hdr->rec_encoding_map[0]));
+ memset(hdr->tag_encoding_map, 0,
+ CRAM_MAP_HASH * sizeof(hdr->tag_encoding_map[0]));
+
+ if (!hdr->preservation_map) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ /* Initialise defaults for preservation map */
+ hdr->mapped_qs_included = 0;
+ hdr->unmapped_qs_included = 0;
+ hdr->unmapped_placed = 0;
+ hdr->qs_included = 0;
+ hdr->read_names_included = 0;
+ hdr->AP_delta = 1;
+ memcpy(hdr->substitution_matrix, "CGTNAGTNACTNACGNACGT", 20);
+
+ /* Preservation map */
+ cp += safe_itf8_get(cp, endp, &map_size); cp_copy = cp;
+ cp += safe_itf8_get(cp, endp, &map_count);
+ for (i = 0; i < map_count; i++) {
+ pmap_t hd;
+ khint_t k;
+ int r;
+
+ if (endp - cp < 2) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ cp += 2;
+ switch(CRAM_KEY(cp[-2],cp[-1])) {
+ case CRAM_KEY('M','I'):
+ hd.i = *cp++;
+ k = kh_put(map, hdr->preservation_map, "MI", &r);
+ if (-1 == r) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ kh_val(hdr->preservation_map, k) = hd;
+ hdr->mapped_qs_included = hd.i;
+ break;
+
+ case CRAM_KEY('U','I'):
+ hd.i = *cp++;
+ k = kh_put(map, hdr->preservation_map, "UI", &r);
+ if (-1 == r) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ kh_val(hdr->preservation_map, k) = hd;
+ hdr->unmapped_qs_included = hd.i;
+ break;
+
+ case CRAM_KEY('P','I'):
+ hd.i = *cp++;
+ k = kh_put(map, hdr->preservation_map, "PI", &r);
+ if (-1 == r) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ kh_val(hdr->preservation_map, k) = hd;
+ hdr->unmapped_placed = hd.i;
+ break;
+
+ case CRAM_KEY('R','N'):
+ hd.i = *cp++;
+ k = kh_put(map, hdr->preservation_map, "RN", &r);
+ if (-1 == r) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ kh_val(hdr->preservation_map, k) = hd;
+ hdr->read_names_included = hd.i;
+ break;
+
+ case CRAM_KEY('A','P'):
+ hd.i = *cp++;
+ k = kh_put(map, hdr->preservation_map, "AP", &r);
+ if (-1 == r) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ kh_val(hdr->preservation_map, k) = hd;
+ hdr->AP_delta = hd.i;
+ break;
+
+ case CRAM_KEY('R','R'):
+ hd.i = *cp++;
+ k = kh_put(map, hdr->preservation_map, "RR", &r);
+ if (-1 == r) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ kh_val(hdr->preservation_map, k) = hd;
+ fd->no_ref = !hd.i;
+ break;
+
+ case CRAM_KEY('S','M'):
+ if (endp - cp < 5) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ hdr->substitution_matrix[0][(cp[0]>>6)&3] = 'C';
+ hdr->substitution_matrix[0][(cp[0]>>4)&3] = 'G';
+ hdr->substitution_matrix[0][(cp[0]>>2)&3] = 'T';
+ hdr->substitution_matrix[0][(cp[0]>>0)&3] = 'N';
+
+ hdr->substitution_matrix[1][(cp[1]>>6)&3] = 'A';
+ hdr->substitution_matrix[1][(cp[1]>>4)&3] = 'G';
+ hdr->substitution_matrix[1][(cp[1]>>2)&3] = 'T';
+ hdr->substitution_matrix[1][(cp[1]>>0)&3] = 'N';
+
+ hdr->substitution_matrix[2][(cp[2]>>6)&3] = 'A';
+ hdr->substitution_matrix[2][(cp[2]>>4)&3] = 'C';
+ hdr->substitution_matrix[2][(cp[2]>>2)&3] = 'T';
+ hdr->substitution_matrix[2][(cp[2]>>0)&3] = 'N';
+
+ hdr->substitution_matrix[3][(cp[3]>>6)&3] = 'A';
+ hdr->substitution_matrix[3][(cp[3]>>4)&3] = 'C';
+ hdr->substitution_matrix[3][(cp[3]>>2)&3] = 'G';
+ hdr->substitution_matrix[3][(cp[3]>>0)&3] = 'N';
+
+ hdr->substitution_matrix[4][(cp[4]>>6)&3] = 'A';
+ hdr->substitution_matrix[4][(cp[4]>>4)&3] = 'C';
+ hdr->substitution_matrix[4][(cp[4]>>2)&3] = 'G';
+ hdr->substitution_matrix[4][(cp[4]>>0)&3] = 'T';
+
+ hd.p = cp;
+ cp += 5;
+
+ k = kh_put(map, hdr->preservation_map, "SM", &r);
+ if (-1 == r) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ kh_val(hdr->preservation_map, k) = hd;
+ break;
+
+ case CRAM_KEY('T','D'): {
+ int sz = cram_decode_TD(cp, endp, hdr); // tag dictionary
+ if (sz < 0) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ hd.p = cp;
+ cp += sz;
+
+ k = kh_put(map, hdr->preservation_map, "TD", &r);
+ if (-1 == r) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ kh_val(hdr->preservation_map, k) = hd;
+ break;
+ }
+
+ default:
+ fprintf(stderr, "Unrecognised preservation map key %c%c\n",
+ cp[-2], cp[-1]);
+ // guess byte;
+ cp++;
+ break;
+ }
+ }
+ if (cp - cp_copy != map_size) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ /* Record encoding map */
+ cp += safe_itf8_get(cp, endp, &map_size); cp_copy = cp;
+ cp += safe_itf8_get(cp, endp, &map_count);
+ for (i = 0; i < map_count; i++) {
+ char *key = cp;
+ int32_t encoding = E_NULL;
+ int32_t size = 0;
+ cram_map *m = malloc(sizeof(*m)); // FIXME: use pooled_alloc
+
+ if (!m || endp - cp < 4) {
+ free(m);
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ cp += 2;
+ cp += safe_itf8_get(cp, endp, &encoding);
+ cp += safe_itf8_get(cp, endp, &size);
+
+ // Fill out cram_map purely for cram_dump to dump out.
+ m->key = (key[0]<<8)|key[1];
+ m->encoding = encoding;
+ m->size = size;
+ m->offset = cp - (char *)b->data;
+ m->codec = NULL;
+
+ if (m->encoding == E_NULL)
+ continue;
+
+ if (size < 0 || endp - cp < size) {
+ free(m);
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ //printf("%s codes for %.2s\n", cram_encoding2str(encoding), key);
+
+ /*
+ * For CRAM1.0 CF and BF are Byte and not Int.
+ * Practically speaking it makes no difference unless we have a
+ * 1.0 format file that stores these in EXTERNAL as only then
+ * does Byte vs Int matter.
+ *
+ * Neither this C code nor Java reference implementations did this,
+ * so we gloss over it and treat them as int.
+ */
+
+ if (key[0] == 'B' && key[1] == 'F') {
+ if (!(hdr->codecs[DS_BF] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'C' && key[1] == 'F') {
+ if (!(hdr->codecs[DS_CF] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'R' && key[1] == 'I') {
+ if (!(hdr->codecs[DS_RI] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'R' && key[1] == 'L') {
+ if (!(hdr->codecs[DS_RL] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'A' && key[1] == 'P') {
+ if (!(hdr->codecs[DS_AP] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'R' && key[1] == 'G') {
+ if (!(hdr->codecs[DS_RG] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'M' && key[1] == 'F') {
+ if (!(hdr->codecs[DS_MF] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'N' && key[1] == 'S') {
+ if (!(hdr->codecs[DS_NS] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'N' && key[1] == 'P') {
+ if (!(hdr->codecs[DS_NP] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'T' && key[1] == 'S') {
+ if (!(hdr->codecs[DS_TS] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'N' && key[1] == 'F') {
+ if (!(hdr->codecs[DS_NF] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'T' && key[1] == 'C') {
+ if (!(hdr->codecs[DS_TC] = cram_decoder_init(encoding, cp, size,
+ E_BYTE,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'T' && key[1] == 'N') {
+ if (!(hdr->codecs[DS_TN] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'F' && key[1] == 'N') {
+ if (!(hdr->codecs[DS_FN] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'F' && key[1] == 'C') {
+ if (!(hdr->codecs[DS_FC] = cram_decoder_init(encoding, cp, size,
+ E_BYTE,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'F' && key[1] == 'P') {
+ if (!(hdr->codecs[DS_FP] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'B' && key[1] == 'S') {
+ if (!(hdr->codecs[DS_BS] = cram_decoder_init(encoding, cp, size,
+ E_BYTE,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'I' && key[1] == 'N') {
+ if (!(hdr->codecs[DS_IN] = cram_decoder_init(encoding, cp, size,
+ E_BYTE_ARRAY,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'S' && key[1] == 'C') {
+ if (!(hdr->codecs[DS_SC] = cram_decoder_init(encoding, cp, size,
+ E_BYTE_ARRAY,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'D' && key[1] == 'L') {
+ if (!(hdr->codecs[DS_DL] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'B' && key[1] == 'A') {
+ if (!(hdr->codecs[DS_BA] = cram_decoder_init(encoding, cp, size,
+ E_BYTE,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'B' && key[1] == 'B') {
+ if (!(hdr->codecs[DS_BB] = cram_decoder_init(encoding, cp, size,
+ E_BYTE_ARRAY,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'R' && key[1] == 'S') {
+ if (!(hdr->codecs[DS_RS] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'P' && key[1] == 'D') {
+ if (!(hdr->codecs[DS_PD] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'H' && key[1] == 'C') {
+ if (!(hdr->codecs[DS_HC] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'M' && key[1] == 'Q') {
+ if (!(hdr->codecs[DS_MQ] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'R' && key[1] == 'N') {
+ if (!(hdr->codecs[DS_RN] = cram_decoder_init(encoding, cp, size,
+ E_BYTE_ARRAY_BLOCK,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'Q' && key[1] == 'S') {
+ if (!(hdr->codecs[DS_QS] = cram_decoder_init(encoding, cp, size,
+ E_BYTE,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'Q' && key[1] == 'Q') {
+ if (!(hdr->codecs[DS_QQ] = cram_decoder_init(encoding, cp, size,
+ E_BYTE_ARRAY,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'T' && key[1] == 'L') {
+ if (!(hdr->codecs[DS_TL] = cram_decoder_init(encoding, cp, size,
+ E_INT,
+ fd->version))) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+ } else if (key[0] == 'T' && key[1] == 'M') {
+ } else if (key[0] == 'T' && key[1] == 'V') {
+ } else
+ fprintf(stderr, "Unrecognised key: %.2s\n", key);
+
+ cp += size;
+
+ m->next = hdr->rec_encoding_map[CRAM_MAP(key[0], key[1])];
+ hdr->rec_encoding_map[CRAM_MAP(key[0], key[1])] = m;
+ }
+ if (cp - cp_copy != map_size) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ /* Tag encoding map */
+ cp += safe_itf8_get(cp, endp, &map_size); cp_copy = cp;
+ cp += safe_itf8_get(cp, endp, &map_count);
+ for (i = 0; i < map_count; i++) {
+ int32_t encoding = E_NULL;
+ int32_t size = 0;
+ cram_map *m = malloc(sizeof(*m)); // FIXME: use pooled_alloc
+ char *key;
+
+ if (!m || endp - cp < 6) {
+ free(m);
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ key = cp + 1;
+ m->key = (key[0]<<16)|(key[1]<<8)|key[2];
+
+ cp += 4; // Strictly ITF8, but this suffices
+ cp += safe_itf8_get(cp, endp, &encoding);
+ cp += safe_itf8_get(cp, endp, &size);
+
+ m->encoding = encoding;
+ m->size = size;
+ m->offset = cp - (char *)b->data;
+ if (size < 0 || endp - cp < size ||
+ !(m->codec = cram_decoder_init(encoding, cp, size,
+ E_BYTE_ARRAY_BLOCK, fd->version))) {
+ cram_free_compression_header(hdr);
+ free(m);
+ return NULL;
+ }
+
+ cp += size;
+
+ m->next = hdr->tag_encoding_map[CRAM_MAP(key[0],key[1])];
+ hdr->tag_encoding_map[CRAM_MAP(key[0],key[1])] = m;
+ }
+ if (cp - cp_copy != map_size) {
+ cram_free_compression_header(hdr);
+ return NULL;
+ }
+
+ return hdr;
+}
+
+/*
+ * Note we also need to scan through the record encoding map to
+ * see which data series share the same block, either external or
+ * CORE. For example if we need the BF data series but MQ and CF
+ * are also encoded in the same block then we need to add those in
+ * as a dependency in order to correctly decode BF.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_dependent_data_series(cram_fd *fd,
+ cram_block_compression_hdr *hdr,
+ cram_slice *s) {
+ int *block_used;
+ int core_used = 0;
+ int i;
+ static int i_to_id[] = {
+ DS_BF, DS_AP, DS_FP, DS_RL, DS_DL, DS_NF, DS_BA, DS_QS,
+ DS_FC, DS_FN, DS_BS, DS_IN, DS_RG, DS_MQ, DS_TL, DS_RN,
+ DS_NS, DS_NP, DS_TS, DS_MF, DS_CF, DS_RI, DS_RS, DS_PD,
+ DS_HC, DS_SC, DS_BB, DS_QQ,
+ };
+ uint32_t orig_ds;
+
+ /*
+ * Set the data_series bit field based on fd->required_fields
+ * contents.
+ */
+ if (fd->required_fields && fd->required_fields != INT_MAX) {
+ hdr->data_series = 0;
+
+ if (fd->required_fields & SAM_QNAME)
+ hdr->data_series |= CRAM_RN;
+
+ if (fd->required_fields & SAM_FLAG)
+ hdr->data_series |= CRAM_BF;
+
+ if (fd->required_fields & SAM_RNAME)
+ hdr->data_series |= CRAM_RI | CRAM_BF;
+
+ if (fd->required_fields & SAM_POS)
+ hdr->data_series |= CRAM_AP | CRAM_BF;
+
+ if (fd->required_fields & SAM_MAPQ)
+ hdr->data_series |= CRAM_MQ;
+
+ if (fd->required_fields & SAM_CIGAR)
+ hdr->data_series |= CRAM_CIGAR;
+
+ if (fd->required_fields & SAM_RNEXT)
+ hdr->data_series |= CRAM_CF | CRAM_NF | CRAM_RI | CRAM_NS |CRAM_BF;
+
+ if (fd->required_fields & SAM_PNEXT)
+ hdr->data_series |= CRAM_CF | CRAM_NF | CRAM_AP | CRAM_NP | CRAM_BF;
+
+ if (fd->required_fields & SAM_TLEN)
+ hdr->data_series |= CRAM_CF | CRAM_NF | CRAM_AP | CRAM_TS |
+ CRAM_BF | CRAM_MF | CRAM_RI | CRAM_CIGAR;
+
+ if (fd->required_fields & SAM_SEQ)
+ hdr->data_series |= CRAM_SEQ;
+
+ if (!(fd->required_fields & SAM_AUX))
+ // No easy way to get MD/NM without other tags at present
+ fd->decode_md = 0;
+
+ if (fd->required_fields & SAM_QUAL)
+ hdr->data_series |= CRAM_QUAL;
+
+ if (fd->required_fields & SAM_AUX)
+ hdr->data_series |= CRAM_RG | CRAM_TL | CRAM_aux;
+
+ if (fd->required_fields & SAM_RGAUX)
+ hdr->data_series |= CRAM_RG | CRAM_BF;
+
+ // Always uncompress CORE block
+ if (cram_uncompress_block(s->block[0]))
+ return -1;
+ } else {
+ hdr->data_series = CRAM_ALL;
+
+ for (i = 0; i < s->hdr->num_blocks; i++) {
+ if (cram_uncompress_block(s->block[i]))
+ return -1;
+ }
+
+ return 0;
+ }
+
+ block_used = calloc(s->hdr->num_blocks+1, sizeof(int));
+ if (!block_used)
+ return -1;
+
+ do {
+ /*
+ * Also set data_series based on code prerequisites. Eg if we need
+ * CRAM_QS then we also need to know CRAM_RL so we know how long it
+ * is, or if we need FC/FP then we also need FN (number of features).
+ *
+ * It's not reciprocal though. We may be needing to decode FN
+ * but have no need to decode FC, FP and cigar ops.
+ */
+ if (hdr->data_series & CRAM_RS) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_PD) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_HC) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_QS) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_IN) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_SC) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_BS) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_DL) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_BA) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_BB) hdr->data_series |= CRAM_FC|CRAM_FP;
+ if (hdr->data_series & CRAM_QQ) hdr->data_series |= CRAM_FC|CRAM_FP;
+
+ // cram_decode_seq() needs seq[] array
+ if (hdr->data_series & (CRAM_SEQ|CRAM_CIGAR)) hdr->data_series |= CRAM_RL;
+
+ if (hdr->data_series & CRAM_FP) hdr->data_series |= CRAM_FC;
+ if (hdr->data_series & CRAM_FC) hdr->data_series |= CRAM_FN;
+ if (hdr->data_series & CRAM_aux) hdr->data_series |= CRAM_TL;
+ if (hdr->data_series & CRAM_MF) hdr->data_series |= CRAM_CF;
+ if (hdr->data_series & CRAM_MQ) hdr->data_series |= CRAM_BF;
+ if (hdr->data_series & CRAM_BS) hdr->data_series |= CRAM_RI;
+ if (hdr->data_series & (CRAM_MF |CRAM_NS |CRAM_NP |CRAM_TS |CRAM_NF))
+ hdr->data_series |= CRAM_CF;
+ if (!hdr->read_names_included && hdr->data_series & CRAM_RN)
+ hdr->data_series |= CRAM_CF | CRAM_NF;
+ if (hdr->data_series & (CRAM_BA | CRAM_QS | CRAM_BB | CRAM_QQ))
+ hdr->data_series |= CRAM_BF | CRAM_CF | CRAM_RL;
+
+ orig_ds = hdr->data_series;
+
+ // Find which blocks are in use.
+ for (i = 0; i < sizeof(i_to_id)/sizeof(*i_to_id); i++) {
+ int bnum1, bnum2, j;
+ cram_codec *c = hdr->codecs[i_to_id[i]];
+
+ if (!(hdr->data_series & (1<<i)))
+ continue;
+
+ if (!c)
+ continue;
+
+ bnum1 = cram_codec_to_id(c, &bnum2);
+
+ for (;;) {
+ switch (bnum1) {
+ case -2:
+ break;
+
+ case -1:
+ core_used = 1;
+ break;
+
+ default:
+ for (j = 0; j < s->hdr->num_blocks; j++) {
+ if (s->block[j]->content_type == EXTERNAL &&
+ s->block[j]->content_id == bnum1) {
+ block_used[j] = 1;
+ if (cram_uncompress_block(s->block[j])) {
+ free(block_used);
+ return -1;
+ }
+ }
+ }
+ break;
+ }
+
+ if (bnum2 == -2 || bnum1 == bnum2)
+ break;
+
+ bnum1 = bnum2; // 2nd pass
+ }
+ }
+
+ // Tags too
+ if ((fd->required_fields & SAM_AUX) ||
+ (hdr->data_series & CRAM_aux)) {
+ for (i = 0; i < CRAM_MAP_HASH; i++) {
+ int bnum1, bnum2, j;
+ cram_map *m = hdr->tag_encoding_map[i];
+
+ while (m) {
+ cram_codec *c = m->codec;
+ if (!c)
+ continue;
+
+ bnum1 = cram_codec_to_id(c, &bnum2);
+
+ for (;;) {
+ switch (bnum1) {
+ case -2:
+ break;
+
+ case -1:
+ core_used = 1;
+ break;
+
+ default:
+ for (j = 0; j < s->hdr->num_blocks; j++) {
+ if (s->block[j]->content_type == EXTERNAL &&
+ s->block[j]->content_id == bnum1) {
+ block_used[j] = 1;
+ if (cram_uncompress_block(s->block[j])) {
+ free(block_used);
+ return -1;
+ }
+ }
+ }
+ break;
+ }
+
+ if (bnum2 == -2 || bnum1 == bnum2)
+ break;
+
+ bnum1 = bnum2; // 2nd pass
+ }
+
+ m = m->next;
+ }
+ }
+ }
+
+ // We now know which blocks are in used, so repeat and find
+ // which other data series need to be added.
+ for (i = 0; i < sizeof(i_to_id)/sizeof(*i_to_id); i++) {
+ int bnum1, bnum2, j;
+ cram_codec *c = hdr->codecs[i_to_id[i]];
+
+ if (!c)
+ continue;
+
+ bnum1 = cram_codec_to_id(c, &bnum2);
+
+ for (;;) {
+ switch (bnum1) {
+ case -2:
+ break;
+
+ case -1:
+ if (core_used) {
+ //printf(" + data series %08x:\n", 1<<i);
+ hdr->data_series |= 1<<i;
+ }
+ break;
+
+ default:
+ for (j = 0; j < s->hdr->num_blocks; j++) {
+ if (s->block[j]->content_type == EXTERNAL &&
+ s->block[j]->content_id == bnum1) {
+ if (block_used[j]) {
+ //printf(" + data series %08x:\n", 1<<i);
+ hdr->data_series |= 1<<i;
+ }
+ }
+ }
+ break;
+ }
+
+ if (bnum2 == -2 || bnum1 == bnum2)
+ break;
+
+ bnum1 = bnum2; // 2nd pass
+ }
+ }
+
+ // Tags too
+ for (i = 0; i < CRAM_MAP_HASH; i++) {
+ int bnum1, bnum2, j;
+ cram_map *m = hdr->tag_encoding_map[i];
+
+ while (m) {
+ cram_codec *c = m->codec;
+ if (!c)
+ continue;
+
+ bnum1 = cram_codec_to_id(c, &bnum2);
+
+ for (;;) {
+ switch (bnum1) {
+ case -2:
+ break;
+
+ case -1:
+ //printf(" + data series %08x:\n", CRAM_aux);
+ hdr->data_series |= CRAM_aux;
+ break;
+
+ default:
+ for (j = 0; j < s->hdr->num_blocks; j++) {
+ if (s->block[j]->content_type &&
+ s->block[j]->content_id == bnum1) {
+ if (block_used[j]) {
+ //printf(" + data series %08x:\n",
+ // CRAM_aux);
+ hdr->data_series |= CRAM_aux;
+ }
+ }
+ }
+ break;
+ }
+
+ if (bnum2 == -2 || bnum1 == bnum2)
+ break;
+
+ bnum1 = bnum2; // 2nd pass
+ }
+
+ m = m->next;
+ }
+ }
+ } while (orig_ds != hdr->data_series);
+
+ free(block_used);
+ return 0;
+}
+
+/*
+ * Checks whether an external block is used solely by a single data series.
+ * Returns the codec type if so (EXTERNAL, BYTE_ARRAY_LEN, BYTE_ARRAY_STOP)
+ * or 0 if not (E_NULL).
+ */
+static int cram_ds_unique(cram_block_compression_hdr *hdr, cram_codec *c,
+ int id) {
+ int i, n_id = 0;
+ enum cram_encoding e_type = 0;
+
+ for (i = 0; i < DS_END; i++) {
+ cram_codec *c;
+ int bnum1, bnum2, old_n_id;
+
+ if (!(c = hdr->codecs[i]))
+ continue;
+
+ bnum1 = cram_codec_to_id(c, &bnum2);
+
+ old_n_id = n_id;
+ if (bnum1 == id) {
+ n_id++;
+ e_type = c->codec;
+ }
+ if (bnum2 == id) {
+ n_id++;
+ e_type = c->codec;
+ }
+
+ if (n_id == old_n_id+2)
+ n_id--; // len/val in same place counts once only.
+ }
+
+ return n_id == 1 ? e_type : 0;
+}
+
+/*
+ * Attempts to estimate the size of some blocks so we can preallocate them
+ * before decoding. Although decoding will automatically grow the blocks,
+ * it is typically more efficient to preallocate.
+ */
+void cram_decode_estimate_sizes(cram_block_compression_hdr *hdr, cram_slice *s,
+ int *qual_size, int *name_size,
+ int *q_id) {
+ int bnum1, bnum2;
+ cram_codec *cd;
+
+ *qual_size = 0;
+ *name_size = 0;
+
+ /* Qual */
+ cd = hdr->codecs[DS_QS];
+ bnum1 = cram_codec_to_id(cd, &bnum2);
+ if (bnum1 < 0 && bnum2 >= 0) bnum1 = bnum2;
+ if (cram_ds_unique(hdr, cd, bnum1)) {
+ cram_block *b = cram_get_block_by_id(s, bnum1);
+ if (b) *qual_size = b->uncomp_size;
+ if (q_id && cd->codec == E_EXTERNAL)
+ *q_id = bnum1;
+ }
+
+ /* Name */
+ cd = hdr->codecs[DS_RN];
+ bnum1 = cram_codec_to_id(cd, &bnum2);
+ if (bnum1 < 0 && bnum2 >= 0) bnum1 = bnum2;
+ if (cram_ds_unique(hdr, cd, bnum1)) {
+ cram_block *b = cram_get_block_by_id(s, bnum1);
+ if (b) *name_size = b->uncomp_size;
+ }
+}
+
+
+/* ----------------------------------------------------------------------
+ * CRAM slices
+ */
+
+/*
+ * Decodes a CRAM (un)mapped slice header block.
+ * Returns slice header ptr on success
+ * NULL on failure
+ */
+cram_block_slice_hdr *cram_decode_slice_header(cram_fd *fd, cram_block *b) {
+ cram_block_slice_hdr *hdr;
+ char *cp;
+ char *cp_end;
+ int i;
+
+ if (b->method != RAW) {
+ /* Spec. says slice header should be RAW, but we can future-proof
+ by trying to decode it if it isn't. */
+ if (cram_uncompress_block(b) < 0)
+ return NULL;
+ }
+ cp = (char *)b->data;
+ cp_end = cp + b->uncomp_size;
+
+ if (b->content_type != MAPPED_SLICE &&
+ b->content_type != UNMAPPED_SLICE)
+ return NULL;
+
+ if (!(hdr = calloc(1, sizeof(*hdr))))
+ return NULL;
+
+ hdr->content_type = b->content_type;
+
+ if (b->content_type == MAPPED_SLICE) {
+ cp += safe_itf8_get(cp, cp_end, &hdr->ref_seq_id);
+ cp += safe_itf8_get(cp, cp_end, &hdr->ref_seq_start);
+ cp += safe_itf8_get(cp, cp_end, &hdr->ref_seq_span);
+ }
+ cp += safe_itf8_get(cp, cp_end, &hdr->num_records);
+ hdr->record_counter = 0;
+ if (CRAM_MAJOR_VERS(fd->version) == 2) {
+ int32_t i32 = 0;
+ cp += safe_itf8_get(cp, cp_end, &i32);
+ hdr->record_counter = i32;
+ } else if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ cp += ltf8_get(cp, &hdr->record_counter);
+ }
+
+ cp += safe_itf8_get(cp, cp_end, &hdr->num_blocks);
+
+ cp += safe_itf8_get(cp, cp_end, &hdr->num_content_ids);
+ if (hdr->num_content_ids < 1 ||
+ hdr->num_content_ids >= SIZE_MAX / sizeof(int32_t)) {
+ /* Slice must have at least one data block,
+ and malloc'd size shouldn't wrap. */
+ free(hdr);
+ return NULL;
+ }
+ hdr->block_content_ids = malloc(hdr->num_content_ids * sizeof(int32_t));
+ if (!hdr->block_content_ids) {
+ free(hdr);
+ return NULL;
+ }
+
+ for (i = 0; i < hdr->num_content_ids; i++) {
+ int l = safe_itf8_get(cp, cp_end,
+ &hdr->block_content_ids[i]);
+ if (l <= 0) {
+ free(hdr->block_content_ids);
+ free(hdr);
+ return NULL;
+ }
+ cp += l;
+ }
+
+ if (b->content_type == MAPPED_SLICE) {
+ cp += safe_itf8_get(cp, cp_end, &hdr->ref_base_id);
+ }
+
+ if (CRAM_MAJOR_VERS(fd->version) != 1) {
+ if (cp_end - cp < 16) {
+ free(hdr->block_content_ids);
+ free(hdr);
+ return NULL;
+ }
+ memcpy(hdr->md5, cp, 16);
+ } else {
+ memset(hdr->md5, 0, 16);
+ }
+
+ return hdr;
+}
+
+
+#if 0
+/* Returns the number of bits set in val; it the highest bit used */
+static int nbits(int v) {
+ static const int MultiplyDeBruijnBitPosition[32] = {
+ 1, 10, 2, 11, 14, 22, 3, 30, 12, 15, 17, 19, 23, 26, 4, 31,
+ 9, 13, 21, 29, 16, 18, 25, 8, 20, 28, 24, 7, 27, 6, 5, 32
+ };
+
+ v |= v >> 1; // first up to set all bits 1 after the first 1 */
+ v |= v >> 2;
+ v |= v >> 4;
+ v |= v >> 8;
+ v |= v >> 16;
+
+ // DeBruijn magic to find top bit
+ return MultiplyDeBruijnBitPosition[(uint32_t)(v * 0x07C4ACDDU) >> 27];
+}
+#endif
+
+#if 0
+static int sort_freqs(const void *vp1, const void *vp2) {
+ const int i1 = *(const int *)vp1;
+ const int i2 = *(const int *)vp2;
+ return i1-i2;
+}
+#endif
+
+/* ----------------------------------------------------------------------
+ * Primary CRAM sequence decoder
+ */
+
+/*
+ * Internal part of cram_decode_slice().
+ * Generates the sequence, quality and cigar components.
+ */
+static int cram_decode_seq(cram_fd *fd, cram_container *c, cram_slice *s,
+ cram_block *blk, cram_record *cr, SAM_hdr *bfd,
+ int cf, char *seq, char *qual,
+ int has_MD, int has_NM) {
+ int prev_pos = 0, f, r = 0, out_sz = 1;
+ int seq_pos = 1;
+ int cig_len = 0, ref_pos = cr->apos;
+ int32_t fn, i32;
+ enum cigar_op cig_op = BAM_CMATCH;
+ uint32_t *cigar = s->cigar;
+ uint32_t ncigar = s->ncigar;
+ uint32_t cigar_alloc = s->cigar_alloc;
+ uint32_t nm = 0;
+ int32_t md_dist = 0;
+ int orig_aux = 0;
+ int decode_md = fd->decode_md && s->ref && !has_MD;
+ int decode_nm = fd->decode_md && s->ref && !has_NM;
+ uint32_t ds = c->comp_hdr->data_series;
+
+ if ((ds & CRAM_QS) && !(cf & CRAM_FLAG_PRESERVE_QUAL_SCORES)) {
+ memset(qual, 255, cr->len);
+ }
+
+ if (cr->cram_flags & CRAM_FLAG_NO_SEQ)
+ decode_md = decode_nm = 0;
+
+ if (decode_md) {
+ orig_aux = BLOCK_SIZE(s->aux_blk);
+ BLOCK_APPEND(s->aux_blk, "MDZ", 3);
+ }
+
+ if (ds & CRAM_FN) {
+ if (!c->comp_hdr->codecs[DS_FN]) return -1;
+ r |= c->comp_hdr->codecs[DS_FN]->decode(s,c->comp_hdr->codecs[DS_FN],
+ blk, (char *)&fn, &out_sz);
+ if (r) return r;
+ } else {
+ fn = 0;
+ }
+
+ ref_pos--; // count from 0
+ cr->cigar = ncigar;
+
+ if (!(ds & (CRAM_FC | CRAM_FP)))
+ goto skip_cigar;
+
+ for (f = 0; f < fn; f++) {
+ int32_t pos = 0;
+ char op;
+
+ if (ncigar+2 >= cigar_alloc) {
+ cigar_alloc = cigar_alloc ? cigar_alloc*2 : 1024;
+ s->cigar = cigar;
+ if (!(cigar = realloc(cigar, cigar_alloc * sizeof(*cigar))))
+ return -1;
+ }
+
+ if (ds & CRAM_FC) {
+ if (!c->comp_hdr->codecs[DS_FC]) return -1;
+ r |= c->comp_hdr->codecs[DS_FC]->decode(s,
+ c->comp_hdr->codecs[DS_FC],
+ blk,
+ &op, &out_sz);
+ if (r) return r;
+ }
+
+ if (!(ds & CRAM_FP))
+ continue;
+
+ if (!c->comp_hdr->codecs[DS_FP]) return -1;
+ r |= c->comp_hdr->codecs[DS_FP]->decode(s,
+ c->comp_hdr->codecs[DS_FP],
+ blk,
+ (char *)&pos, &out_sz);
+ if (r) return r;
+ pos += prev_pos;
+
+ if (pos <= 0) {
+ fprintf(stderr, "Error: feature position %d before start of read.\n",
+ pos);
+ return -1;
+ }
+
+ if (pos > seq_pos) {
+ if (pos > cr->len+1)
+ return -1;
+
+ if (s->ref && cr->ref_id >= 0) {
+ if (ref_pos + pos - seq_pos > bfd->ref[cr->ref_id].len) {
+ static int whinged = 0;
+ int rlen;
+ if (!whinged)
+ fprintf(stderr, "Ref pos outside of ref "
+ "sequence boundary\n");
+ whinged = 1;
+ rlen = bfd->ref[cr->ref_id].len - ref_pos;
+ if (rlen > 0) {
+ memcpy(&seq[seq_pos-1],
+ &s->ref[ref_pos - s->ref_start +1], rlen);
+ if ((pos - seq_pos) - rlen > 0)
+ memset(&seq[seq_pos-1+rlen], 'N',
+ (pos - seq_pos) - rlen);
+ } else {
+ memset(&seq[seq_pos-1], 'N', cr->len - seq_pos + 1);
+ }
+ } else {
+ memcpy(&seq[seq_pos-1], &s->ref[ref_pos - s->ref_start +1],
+ pos - seq_pos);
+ }
+ }
+#ifdef USE_X
+ if (cig_len && cig_op != BAM_CBASE_MATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ cig_op = BAM_CBASE_MATCH;
+#else
+ if (cig_len && cig_op != BAM_CMATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ cig_op = BAM_CMATCH;
+#endif
+ cig_len += pos - seq_pos;
+ ref_pos += pos - seq_pos;
+ if (md_dist >= 0)
+ md_dist += pos - seq_pos;
+ seq_pos = pos;
+ }
+
+ prev_pos = pos;
+
+ if (!(ds & CRAM_FC))
+ goto skip_cigar;
+
+ if (!(ds & CRAM_FC))
+ continue;
+
+ switch(op) {
+ case 'S': { // soft clip: IN
+ int32_t out_sz2 = 1;
+ int have_sc = 0;
+
+ if (cig_len) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ switch (CRAM_MAJOR_VERS(fd->version)) {
+ case 1:
+ if (ds & CRAM_IN) {
+ r |= c->comp_hdr->codecs[DS_IN]
+ ? c->comp_hdr->codecs[DS_IN]
+ ->decode(s, c->comp_hdr->codecs[DS_IN],
+ blk,
+ cr->len ? &seq[pos-1] : NULL,
+ &out_sz2)
+ : (seq[pos-1] = 'N', out_sz2 = 1, 0);
+ have_sc = 1;
+ }
+ break;
+ case 2:
+ default:
+ if (ds & CRAM_SC) {
+ r |= c->comp_hdr->codecs[DS_SC]
+ ? c->comp_hdr->codecs[DS_SC]
+ ->decode(s, c->comp_hdr->codecs[DS_SC],
+ blk,
+ cr->len ? &seq[pos-1] : NULL,
+ &out_sz2)
+ : (seq[pos-1] = 'N', out_sz2 = 1, 0);
+ have_sc = 1;
+ }
+ break;
+
+// default:
+// r |= c->comp_hdr->codecs[DS_BB]
+// ? c->comp_hdr->codecs[DS_BB]
+// ->decode(s, c->comp_hdr->codecs[DS_BB],
+// blk, &seq[pos-1], &out_sz2)
+// : (seq[pos-1] = 'N', out_sz2 = 1, 0);
+ }
+ if (have_sc) {
+ if (r) return r;
+ cigar[ncigar++] = (out_sz2<<4) + BAM_CSOFT_CLIP;
+ cig_op = BAM_CSOFT_CLIP;
+ seq_pos += out_sz2;
+ }
+ break;
+ }
+
+ case 'X': { // Substitution; BS
+ unsigned char base;
+#ifdef USE_X
+ if (cig_len && cig_op != BAM_CBASE_MISMATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ if (ds & CRAM_BS) {
+ if (!c->comp_hdr->codecs[DS_BS]) return -1;
+ r |= c->comp_hdr->codecs[DS_BS]
+ ->decode(s, c->comp_hdr->codecs[DS_BS], blk,
+ (char *)&base, &out_sz);
+ if (pos-1 < cr->len)
+ seq[pos-1] = 'N'; // FIXME look up BS=base value
+ }
+ cig_op = BAM_CBASE_MISMATCH;
+#else
+ int ref_base;
+ if (cig_len && cig_op != BAM_CMATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ if (ds & CRAM_BS) {
+ if (!c->comp_hdr->codecs[DS_BS]) return -1;
+ r |= c->comp_hdr->codecs[DS_BS]
+ ->decode(s, c->comp_hdr->codecs[DS_BS], blk,
+ (char *)&base, &out_sz);
+ if (r) return -1;
+ if (ref_pos >= bfd->ref[cr->ref_id].len || !s->ref) {
+ if (pos-1 < cr->len)
+ seq[pos-1] = c->comp_hdr->
+ substitution_matrix[fd->L1['N']][base];
+ if (decode_md || decode_nm) {
+ if (md_dist >= 0 && decode_md)
+ BLOCK_APPEND_UINT(s->aux_blk, md_dist);
+ md_dist = -1;
+ nm--;
+ }
+ } else {
+ unsigned char ref_call = ref_pos <= s->ref_end
+ ? (uc)s->ref[ref_pos - s->ref_start +1]
+ : 'N';
+ ref_base = fd->L1[ref_call];
+ if (pos-1 < cr->len)
+ seq[pos-1] = c->comp_hdr->
+ substitution_matrix[ref_base][base];
+ if (decode_md) {
+ BLOCK_APPEND_UINT(s->aux_blk, md_dist);
+ BLOCK_APPEND_CHAR(s->aux_blk, ref_call);
+ md_dist = 0;
+ }
+ }
+ }
+ cig_op = BAM_CMATCH;
+#endif
+ nm++;
+ cig_len++;
+ seq_pos++;
+ ref_pos++;
+ break;
+ }
+
+ case 'D': { // Deletion; DL
+ if (cig_len && cig_op != BAM_CDEL) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ if (ds & CRAM_DL) {
+ if (!c->comp_hdr->codecs[DS_DL]) return -1;
+ r |= c->comp_hdr->codecs[DS_DL]
+ ->decode(s, c->comp_hdr->codecs[DS_DL], blk,
+ (char *)&i32, &out_sz);
+ if (r) return r;
+ if (decode_md || decode_nm) {
+ if (md_dist >= 0 && decode_md)
+ BLOCK_APPEND_UINT(s->aux_blk, md_dist);
+ if (ref_pos + i32 <= bfd->ref[cr->ref_id].len) {
+ if (decode_md) {
+ BLOCK_APPEND_CHAR(s->aux_blk, '^');
+ BLOCK_APPEND(s->aux_blk,
+ &s->ref[ref_pos - s->ref_start +1],
+ i32);
+ md_dist = 0;
+ }
+ nm += i32;
+ } else {
+ uint32_t dlen;
+ if (bfd->ref[cr->ref_id].len >= ref_pos) {
+ if (decode_md) {
+ BLOCK_APPEND_CHAR(s->aux_blk, '^');
+ BLOCK_APPEND(s->aux_blk,
+ &s->ref[ref_pos - s->ref_start+1],
+ bfd->ref[cr->ref_id].len-ref_pos);
+ BLOCK_APPEND_UINT(s->aux_blk, 0);
+ }
+ dlen = i32 - (bfd->ref[cr->ref_id].len - ref_pos);
+ nm += i32 - dlen;
+ } else {
+ dlen = i32;
+ }
+
+ md_dist = -1;
+ }
+ }
+ cig_op = BAM_CDEL;
+ cig_len += i32;
+ ref_pos += i32;
+ //printf(" %d: DL = %d (ret %d)\n", f, i32, r);
+ }
+ break;
+ }
+
+ case 'I': { // Insertion (several bases); IN
+ int32_t out_sz2 = 1;
+
+ if (cig_len && cig_op != BAM_CINS) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+
+ if (ds & CRAM_IN) {
+ if (!c->comp_hdr->codecs[DS_IN]) return -1;
+ r |= c->comp_hdr->codecs[DS_IN]
+ ->decode(s, c->comp_hdr->codecs[DS_IN], blk,
+ cr->len ? &seq[pos-1] : NULL,
+ &out_sz2);
+ if (r) return r;
+ cig_op = BAM_CINS;
+ cig_len += out_sz2;
+ seq_pos += out_sz2;
+ nm += out_sz2;
+ //printf(" %d: IN(I) = %.*s (ret %d, out_sz %d)\n", f, out_sz2, dat, r, out_sz2);
+ }
+ break;
+ }
+
+ case 'i': { // Insertion (single base); BA
+ if (cig_len && cig_op != BAM_CINS) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ if (ds & CRAM_BA) {
+ if (!c->comp_hdr->codecs[DS_BA]) return -1;
+ r |= c->comp_hdr->codecs[DS_BA]
+ ->decode(s, c->comp_hdr->codecs[DS_BA], blk,
+ cr->len ? &seq[pos-1] : NULL,
+ &out_sz);
+ if (r) return r;
+ }
+ cig_op = BAM_CINS;
+ cig_len++;
+ seq_pos++;
+ nm++;
+ break;
+ }
+
+ case 'b': { // Several bases
+ int32_t len = 1;
+
+ if (cig_len && cig_op != BAM_CMATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+
+ if (ds & CRAM_BB) {
+ if (!c->comp_hdr->codecs[DS_BB]) return -1;
+ r |= c->comp_hdr->codecs[DS_BB]
+ ->decode(s, c->comp_hdr->codecs[DS_BB], blk,
+ cr->len ? &seq[pos-1] : NULL,
+ &len);
+ if (r) return r;
+
+ if (decode_md || decode_nm) {
+ int x;
+ if (md_dist >= 0 && decode_md)
+ BLOCK_APPEND_UINT(s->aux_blk, md_dist);
+
+ for (x = 0; x < len; x++) {
+ if (x && decode_md)
+ BLOCK_APPEND_UINT(s->aux_blk, 0);
+ if (ref_pos+x >= bfd->ref[cr->ref_id].len || !s->ref) {
+ md_dist = -1;
+ break;
+ } else {
+ if (decode_md) {
+ char r = s->ref[ref_pos+x-s->ref_start +1];
+ BLOCK_APPEND_CHAR(s->aux_blk, r);
+ }
+ }
+ }
+
+ nm += x;
+ }
+ }
+
+ cig_op = BAM_CMATCH;
+
+ cig_len+=len;
+ seq_pos+=len;
+ ref_pos+=len;
+ //prev_pos+=len;
+ break;
+ }
+
+ case 'q': { // Several quality values
+ int32_t len = 1;
+
+ if (cig_len && cig_op != BAM_CMATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+
+ if (ds & CRAM_QQ) {
+ if (!c->comp_hdr->codecs[DS_QQ]) return -1;
+ r |= c->comp_hdr->codecs[DS_QQ]
+ ->decode(s, c->comp_hdr->codecs[DS_QQ], blk,
+ (char *)&qual[pos-1], &len);
+ if (r) return r;
+ }
+
+ cig_op = BAM_CMATCH;
+
+ cig_len+=len;
+ seq_pos+=len;
+ ref_pos+=len;
+ //prev_pos+=len;
+ break;
+ }
+
+ case 'B': { // Read base; BA, QS
+#ifdef USE_X
+ if (cig_len && cig_op != BAM_CBASE_MISMATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+#else
+ if (cig_len && cig_op != BAM_CMATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+#endif
+ if (ds & CRAM_BA) {
+ if (!c->comp_hdr->codecs[DS_BA]) return -1;
+ r |= c->comp_hdr->codecs[DS_BA]
+ ->decode(s, c->comp_hdr->codecs[DS_BA], blk,
+ cr->len ? &seq[pos-1] : NULL,
+ &out_sz);
+
+ if (decode_md || decode_nm) {
+ if (md_dist >= 0 && decode_md)
+ BLOCK_APPEND_UINT(s->aux_blk, md_dist);
+ if (ref_pos >= bfd->ref[cr->ref_id].len || !s->ref) {
+ md_dist = -1;
+ } else {
+ if (decode_md)
+ BLOCK_APPEND_CHAR(s->aux_blk,
+ s->ref[ref_pos-s->ref_start +1]);
+ nm++;
+ md_dist = 0;
+ }
+ }
+ }
+ if (ds & CRAM_QS) {
+ if (!c->comp_hdr->codecs[DS_QS]) return -1;
+ r |= c->comp_hdr->codecs[DS_QS]
+ ->decode(s, c->comp_hdr->codecs[DS_QS], blk,
+ (char *)&qual[pos-1], &out_sz);
+ }
+#ifdef USE_X
+ cig_op = BAM_CBASE_MISMATCH;
+#else
+ cig_op = BAM_CMATCH;
+#endif
+ cig_len++;
+ seq_pos++;
+ ref_pos++;
+ //printf(" %d: BA/QS(B) = %c/%d (ret %d)\n", f, i32, qc, r);
+ break;
+ }
+
+ case 'Q': { // Quality score; QS
+ if (ds & CRAM_QS) {
+ if (!c->comp_hdr->codecs[DS_QS]) return -1;
+ r |= c->comp_hdr->codecs[DS_QS]
+ ->decode(s, c->comp_hdr->codecs[DS_QS], blk,
+ (char *)&qual[pos-1], &out_sz);
+ //printf(" %d: QS = %d (ret %d)\n", f, qc, r);
+ }
+ break;
+ }
+
+ case 'H': { // hard clip; HC
+ if (cig_len && cig_op != BAM_CHARD_CLIP) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ if (ds & CRAM_HC) {
+ if (!c->comp_hdr->codecs[DS_HC]) return -1;
+ r |= c->comp_hdr->codecs[DS_HC]
+ ->decode(s, c->comp_hdr->codecs[DS_HC], blk,
+ (char *)&i32, &out_sz);
+ if (r) return r;
+ cig_op = BAM_CHARD_CLIP;
+ cig_len += i32;
+ }
+ break;
+ }
+
+ case 'P': { // padding; PD
+ if (cig_len && cig_op != BAM_CPAD) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ if (ds & CRAM_PD) {
+ if (!c->comp_hdr->codecs[DS_PD]) return -1;
+ r |= c->comp_hdr->codecs[DS_PD]
+ ->decode(s, c->comp_hdr->codecs[DS_PD], blk,
+ (char *)&i32, &out_sz);
+ if (r) return r;
+ cig_op = BAM_CPAD;
+ cig_len += i32;
+ nm += i32;
+ }
+ break;
+ }
+
+ case 'N': { // Ref skip; RS
+ if (cig_len && cig_op != BAM_CREF_SKIP) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ if (ds & CRAM_RS) {
+ if (!c->comp_hdr->codecs[DS_RS]) return -1;
+ r |= c->comp_hdr->codecs[DS_RS]
+ ->decode(s, c->comp_hdr->codecs[DS_RS], blk,
+ (char *)&i32, &out_sz);
+ if (r) return r;
+ cig_op = BAM_CREF_SKIP;
+ cig_len += i32;
+ ref_pos += i32;
+ nm += i32;
+ }
+ break;
+ }
+
+ default:
+ fprintf(stderr, "Error: Unknown feature code '%c'\n", op);
+ return -1;
+ }
+ }
+
+ if (!(ds & CRAM_FC))
+ goto skip_cigar;
+
+ /* An implicit match op for any unaccounted for bases */
+ if ((ds & CRAM_FN) && cr->len >= seq_pos) {
+ if (s->ref) {
+ if (ref_pos + cr->len - seq_pos + 1 > bfd->ref[cr->ref_id].len) {
+ static int whinged = 0;
+ int rlen;
+ if (!whinged)
+ fprintf(stderr, "Ref pos outside of ref sequence boundary\n");
+ whinged = 1;
+ rlen = bfd->ref[cr->ref_id].len - ref_pos;
+ if (rlen > 0) {
+ if (seq_pos-1 + rlen < cr->len)
+ memcpy(&seq[seq_pos-1],
+ &s->ref[ref_pos - s->ref_start +1], rlen);
+ if ((cr->len - seq_pos + 1) - rlen > 0)
+ memset(&seq[seq_pos-1+rlen], 'N',
+ (cr->len - seq_pos + 1) - rlen);
+ } else {
+ if (cr->len - seq_pos + 1 > 0)
+ memset(&seq[seq_pos-1], 'N', cr->len - seq_pos + 1);
+ }
+ } else {
+ if (cr->len - seq_pos + 1 > 0)
+ memcpy(&seq[seq_pos-1], &s->ref[ref_pos - s->ref_start +1],
+ cr->len - seq_pos + 1);
+ ref_pos += cr->len - seq_pos + 1;
+ if (md_dist >= 0)
+ md_dist += cr->len - seq_pos + 1;
+ }
+ }
+
+ if (ncigar+1 >= cigar_alloc) {
+ cigar_alloc = cigar_alloc ? cigar_alloc*2 : 1024;
+ s->cigar = cigar;
+ if (!(cigar = realloc(cigar, cigar_alloc * sizeof(*cigar))))
+ return -1;
+ }
+#ifdef USE_X
+ if (cig_len && cig_op != BAM_CBASE_MATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ cig_op = BAM_CBASE_MATCH;
+#else
+ if (cig_len && cig_op != BAM_CMATCH) {
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ cig_len = 0;
+ }
+ cig_op = BAM_CMATCH;
+#endif
+ cig_len += cr->len - seq_pos+1;
+ }
+
+ skip_cigar:
+
+ if ((ds & CRAM_FN) && decode_md) {
+ if (md_dist >= 0)
+ BLOCK_APPEND_UINT(s->aux_blk, md_dist);
+ }
+
+ if (cig_len) {
+ if (ncigar >= cigar_alloc) {
+ cigar_alloc = cigar_alloc ? cigar_alloc*2 : 1024;
+ s->cigar = cigar;
+ if (!(cigar = realloc(cigar, cigar_alloc * sizeof(*cigar))))
+ return -1;
+ }
+
+ cigar[ncigar++] = (cig_len<<4) + cig_op;
+ }
+
+ cr->ncigar = ncigar - cr->cigar;
+ cr->aend = ref_pos;
+
+ //printf("2: %.*s %d .. %d\n", cr->name_len, DSTRING_STR(name_ds) + cr->name, cr->apos, ref_pos);
+
+ if (ds & CRAM_MQ) {
+ if (!c->comp_hdr->codecs[DS_MQ]) return -1;
+ r |= c->comp_hdr->codecs[DS_MQ]
+ ->decode(s, c->comp_hdr->codecs[DS_MQ], blk,
+ (char *)&cr->mqual, &out_sz);
+ } else {
+ cr->mqual = 40;
+ }
+
+ if ((ds & CRAM_QS) && (cf & CRAM_FLAG_PRESERVE_QUAL_SCORES)) {
+ int32_t out_sz2 = cr->len;
+
+ if (ds & CRAM_QS) {
+ if (!c->comp_hdr->codecs[DS_QS]) return -1;
+ r |= c->comp_hdr->codecs[DS_QS]
+ ->decode(s, c->comp_hdr->codecs[DS_QS], blk,
+ qual, &out_sz2);
+ }
+ }
+
+ s->cigar = cigar;
+ s->cigar_alloc = cigar_alloc;
+ s->ncigar = ncigar;
+
+ if (cr->cram_flags & CRAM_FLAG_NO_SEQ)
+ cr->len = 0;
+
+ if (decode_md) {
+ BLOCK_APPEND_CHAR(s->aux_blk, '\0'); // null terminate MD:Z:
+ cr->aux_size += BLOCK_SIZE(s->aux_blk) - orig_aux;
+ }
+
+ if (decode_nm) {
+ char buf[7];
+ buf[0] = 'N'; buf[1] = 'M'; buf[2] = 'I';
+ buf[3] = (nm>> 0) & 0xff;
+ buf[4] = (nm>> 8) & 0xff;
+ buf[5] = (nm>>16) & 0xff;
+ buf[6] = (nm>>24) & 0xff;
+ BLOCK_APPEND(s->aux_blk, buf, 7);
+ cr->aux_size += 7;
+ }
+
+ return r;
+}
+
+/*
+ * Quick and simple hash lookup for cram_map arrays
+ */
+static cram_map *map_find(cram_map **map, unsigned char *key, int id) {
+ cram_map *m;
+
+ m = map[CRAM_MAP(key[0],key[1])];
+ while (m && m->key != id)
+ m= m->next;
+
+ return m;
+}
+
+//#define map_find(M,K,I) M[CRAM_MAP(K[0],K[1])];while (m && m->key != I);m= m->next
+
+
+static int cram_decode_aux_1_0(cram_container *c, cram_slice *s,
+ cram_block *blk, cram_record *cr) {
+ int i, r = 0, out_sz = 1;
+ unsigned char ntags;
+
+ if (!c->comp_hdr->codecs[DS_TC]) return -1;
+ r |= c->comp_hdr->codecs[DS_TC]->decode(s, c->comp_hdr->codecs[DS_TC], blk,
+ (char *)&ntags, &out_sz);
+ cr->ntags = ntags;
+
+ //printf("TC=%d\n", cr->ntags);
+ cr->aux_size = 0;
+ cr->aux = BLOCK_SIZE(s->aux_blk);
+
+ for (i = 0; i < cr->ntags; i++) {
+ int32_t id, out_sz = 1;
+ unsigned char tag_data[3];
+ cram_map *m;
+
+ //printf("Tag %d/%d\n", i+1, cr->ntags);
+ if (!c->comp_hdr->codecs[DS_TN]) return -1;
+ r |= c->comp_hdr->codecs[DS_TN]->decode(s, c->comp_hdr->codecs[DS_TN],
+ blk, (char *)&id, &out_sz);
+ if (out_sz == 3) {
+ tag_data[0] = ((char *)&id)[0];
+ tag_data[1] = ((char *)&id)[1];
+ tag_data[2] = ((char *)&id)[2];
+ } else {
+ tag_data[0] = (id>>16) & 0xff;
+ tag_data[1] = (id>>8) & 0xff;
+ tag_data[2] = id & 0xff;
+ }
+
+ m = map_find(c->comp_hdr->tag_encoding_map, tag_data, id);
+ if (!m)
+ return -1;
+ BLOCK_APPEND(s->aux_blk, (char *)tag_data, 3);
+
+ if (!m->codec) return -1;
+ r |= m->codec->decode(s, m->codec, blk, (char *)s->aux_blk, &out_sz);
+
+ cr->aux_size += out_sz + 3;
+ }
+
+ return r;
+}
+
+static int cram_decode_aux(cram_container *c, cram_slice *s,
+ cram_block *blk, cram_record *cr,
+ int *has_MD, int *has_NM) {
+ int i, r = 0, out_sz = 1;
+ int32_t TL = 0;
+ unsigned char *TN;
+ uint32_t ds = c->comp_hdr->data_series;
+
+ if (!(ds & (CRAM_TL|CRAM_aux))) {
+ cr->aux = 0;
+ cr->aux_size = 0;
+ return 0;
+ }
+
+ if (!c->comp_hdr->codecs[DS_TL]) return -1;
+ r |= c->comp_hdr->codecs[DS_TL]->decode(s, c->comp_hdr->codecs[DS_TL], blk,
+ (char *)&TL, &out_sz);
+ if (r || TL < 0 || TL >= c->comp_hdr->nTL)
+ return -1;
+
+ TN = c->comp_hdr->TL[TL];
+ cr->ntags = strlen((char *)TN)/3; // optimise to remove strlen
+
+ //printf("TC=%d\n", cr->ntags);
+ cr->aux_size = 0;
+ cr->aux = BLOCK_SIZE(s->aux_blk);
+
+ if (!(ds & CRAM_aux))
+ return 0;
+
+ for (i = 0; i < cr->ntags; i++) {
+ int32_t id, out_sz = 1;
+ unsigned char tag_data[3];
+ cram_map *m;
+
+ if (TN[0] == 'M' && TN[1] == 'D' && has_MD)
+ *has_MD = 1;
+ if (TN[0] == 'N' && TN[1] == 'M' && has_NM)
+ *has_NM = 1;
+
+ //printf("Tag %d/%d\n", i+1, cr->ntags);
+ tag_data[0] = *TN++;
+ tag_data[1] = *TN++;
+ tag_data[2] = *TN++;
+ id = (tag_data[0]<<16) | (tag_data[1]<<8) | tag_data[2];
+
+ m = map_find(c->comp_hdr->tag_encoding_map, tag_data, id);
+ if (!m)
+ return -1;
+ BLOCK_APPEND(s->aux_blk, (char *)tag_data, 3);
+
+ if (!m->codec) return -1;
+ r |= m->codec->decode(s, m->codec, blk, (char *)s->aux_blk, &out_sz);
+ if (r) break;
+ cr->aux_size += out_sz + 3;
+ }
+
+ return r;
+}
+
+/* Resolve mate pair cross-references between recs within this slice */
+static int cram_decode_slice_xref(cram_slice *s, int required_fields) {
+ int rec;
+
+ if (!(required_fields & (SAM_RNEXT | SAM_PNEXT | SAM_TLEN))) {
+ for (rec = 0; rec < s->hdr->num_records; rec++) {
+ cram_record *cr = &s->crecs[rec];
+
+ cr->tlen = 0;
+ cr->mate_pos = 0;
+ cr->mate_ref_id = -1;
+ }
+
+ return 0;
+ }
+
+ for (rec = 0; rec < s->hdr->num_records; rec++) {
+ cram_record *cr = &s->crecs[rec];
+
+ if (cr->mate_line >= 0) {
+ if (cr->mate_line < s->hdr->num_records) {
+ /*
+ * On the first read, loop through computing lengths.
+ * It's not perfect as we have one slice per reference so we
+ * cannot detect when TLEN should be zero due to seqs that
+ * map to multiple references.
+ *
+ * We also cannot set tlen correct when it spans a slice for
+ * other reasons. This may make tlen too small. Should we
+ * fix this by forcing TLEN to be stored verbatim in such cases?
+ *
+ * Or do we just admit defeat and output 0 for tlen? It's the
+ * safe option...
+ */
+ if (cr->tlen == INT_MIN) {
+ int id1 = rec, id2 = rec;
+ int aleft = cr->apos, aright = cr->aend;
+ int tlen;
+ int ref = cr->ref_id;
+
+ // number of segments starting at the same point.
+ int left_cnt = 0;
+
+ do {
+ if (aleft > s->crecs[id2].apos)
+ aleft = s->crecs[id2].apos, left_cnt = 1;
+ else if (aleft == s->crecs[id2].apos)
+ left_cnt++;
+ if (aright < s->crecs[id2].aend)
+ aright = s->crecs[id2].aend;
+ if (s->crecs[id2].mate_line == -1) {
+ s->crecs[id2].mate_line = rec;
+ break;
+ }
+ if (s->crecs[id2].mate_line <= id2 ||
+ s->crecs[id2].mate_line >= s->hdr->num_records)
+ return -1;
+ id2 = s->crecs[id2].mate_line;
+
+ if (s->crecs[id2].ref_id != ref)
+ ref = -1;
+ } while (id2 != id1);
+
+ if (ref != -1) {
+ tlen = aright - aleft + 1;
+ id1 = id2 = rec;
+
+ /*
+ * When we have two seqs with identical start and
+ * end coordinates, set +/- tlen based on 1st/last
+ * bit flags instead, as a tie breaker.
+ */
+ if (s->crecs[id2].apos == aleft) {
+ if (left_cnt == 1 ||
+ (s->crecs[id2].flags & BAM_FREAD1))
+ s->crecs[id2].tlen = tlen;
+ else
+ s->crecs[id2].tlen = -tlen;
+ } else {
+ s->crecs[id2].tlen = -tlen;
+ }
+
+ id2 = s->crecs[id2].mate_line;
+ while (id2 != id1) {
+ if (s->crecs[id2].apos == aleft) {
+ if (left_cnt == 1 ||
+ (s->crecs[id2].flags & BAM_FREAD1))
+ s->crecs[id2].tlen = tlen;
+ else
+ s->crecs[id2].tlen = -tlen;
+ } else {
+ s->crecs[id2].tlen = -tlen;
+ }
+ id2 = s->crecs[id2].mate_line;
+ }
+ } else {
+ id1 = id2 = rec;
+
+ s->crecs[id2].tlen = 0;
+ id2 = s->crecs[id2].mate_line;
+ while (id2 != id1) {
+ s->crecs[id2].tlen = 0;
+ id2 = s->crecs[id2].mate_line;
+ }
+ }
+ }
+
+ cr->mate_pos = s->crecs[cr->mate_line].apos;
+ cr->mate_ref_id = s->crecs[cr->mate_line].ref_id;
+
+ // paired
+ cr->flags |= BAM_FPAIRED;
+
+ // set mate unmapped if needed
+ if (s->crecs[cr->mate_line].flags & BAM_FUNMAP) {
+ cr->flags |= BAM_FMUNMAP;
+ cr->tlen = 0;
+ }
+ if (cr->flags & BAM_FUNMAP) {
+ cr->tlen = 0;
+ }
+
+ // set mate reversed if needed
+ if (s->crecs[cr->mate_line].flags & BAM_FREVERSE)
+ cr->flags |= BAM_FMREVERSE;
+ } else {
+ fprintf(stderr, "Mate line out of bounds: %d vs [0, %d]\n",
+ cr->mate_line, s->hdr->num_records-1);
+ }
+
+ /* FIXME: construct read names here too if needed */
+ } else {
+ if (cr->mate_flags & CRAM_M_REVERSE) {
+ cr->flags |= BAM_FPAIRED | BAM_FMREVERSE;
+ }
+ if (cr->mate_flags & CRAM_M_UNMAP) {
+ cr->flags |= BAM_FMUNMAP;
+ //cr->mate_ref_id = -1;
+ }
+ if (!(cr->flags & BAM_FPAIRED))
+ cr->mate_ref_id = -1;
+ }
+
+ if (cr->tlen == INT_MIN)
+ cr->tlen = 0; // Just incase
+ }
+ return 0;
+}
+
+static char *md5_print(unsigned char *md5, char *out) {
+ int i;
+ for (i = 0; i < 16; i++) {
+ out[i*2+0] = "0123456789abcdef"[md5[i]>>4];
+ out[i*2+1] = "0123456789abcdef"[md5[i]&15];
+ }
+ out[32] = 0;
+
+ return out;
+}
+
+/*
+ * Decode an entire slice from container blocks. Fills out s->crecs[] array.
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_decode_slice(cram_fd *fd, cram_container *c, cram_slice *s,
+ SAM_hdr *bfd) {
+ cram_block *blk = s->block[0];
+ int32_t bf, ref_id;
+ unsigned char cf;
+ int out_sz, r = 0;
+ int rec;
+ char *seq = NULL, *qual = NULL;
+ int unknown_rg = -1;
+ int embed_ref;
+ char **refs = NULL;
+ uint32_t ds;
+
+ if (cram_dependent_data_series(fd, c->comp_hdr, s) != 0)
+ return -1;
+
+ ds = c->comp_hdr->data_series;
+
+ blk->bit = 7; // MSB first
+
+ // Study the blocks and estimate approx sizes to preallocate.
+ // This looks to speed up decoding by around 8-9%.
+ // We can always shrink back down at the end if we overestimated.
+ // However it's likely that this also saves memory as own growth
+ // factor (*=1.5) is never applied.
+ {
+ int qsize, nsize, q_id;
+ cram_decode_estimate_sizes(c->comp_hdr, s, &qsize, &nsize, &q_id);
+ //fprintf(stderr, "qsize=%d nsize=%d\n", qsize, nsize);
+
+ if (qsize && (ds & CRAM_RL)) BLOCK_RESIZE_EXACT(s->seqs_blk, qsize+1);
+ if (qsize && (ds & CRAM_RL)) BLOCK_RESIZE_EXACT(s->qual_blk, qsize+1);
+ if (nsize && (ds & CRAM_NS)) BLOCK_RESIZE_EXACT(s->name_blk, nsize+1);
+
+ // To do - consider using q_id here to usurp the quality block and
+ // avoid a memcpy during decode.
+ // Specifically when quality is an external block uniquely used by
+ // DS_QS only, then we can set s->qual_blk directly to this
+ // block and save the codec->decode() calls. (Approx 3% cpu saving)
+ }
+
+ /* Look for unknown RG, added as last by Java CRAM? */
+ if (bfd->nrg > 0 &&
+ bfd->rg[bfd->nrg-1].name != NULL &&
+ !strcmp(bfd->rg[bfd->nrg-1].name, "UNKNOWN"))
+ unknown_rg = bfd->nrg-1;
+
+ if (blk->content_type != CORE)
+ return -1;
+
+ if (s->crecs)
+ free(s->crecs);
+ if (!(s->crecs = malloc(s->hdr->num_records * sizeof(*s->crecs))))
+ return -1;
+
+ ref_id = s->hdr->ref_seq_id;
+ embed_ref = s->hdr->ref_base_id >= 0 ? 1 : 0;
+
+ if (ref_id >= 0) {
+ if (embed_ref) {
+ cram_block *b;
+ if (s->hdr->ref_base_id < 0) {
+ fprintf(stderr, "No reference specified and "
+ "no embedded reference is available.\n");
+ return -1;
+ }
+ b = cram_get_block_by_id(s, s->hdr->ref_base_id);
+ if (!b)
+ return -1;
+ if (cram_uncompress_block(b) != 0)
+ return -1;
+ s->ref = (char *)BLOCK_DATA(b);
+ s->ref_start = s->hdr->ref_seq_start;
+ s->ref_end = s->hdr->ref_seq_start + s->hdr->ref_seq_span-1;
+ } else if (!fd->no_ref) {
+ //// Avoid Java cramtools bug by loading entire reference seq
+ //s->ref = cram_get_ref(fd, s->hdr->ref_seq_id, 1, 0);
+ //s->ref_start = 1;
+
+ if (fd->required_fields & SAM_SEQ)
+ s->ref =
+ cram_get_ref(fd, s->hdr->ref_seq_id,
+ s->hdr->ref_seq_start,
+ s->hdr->ref_seq_start + s->hdr->ref_seq_span -1);
+ s->ref_start = s->hdr->ref_seq_start;
+ s->ref_end = s->hdr->ref_seq_start + s->hdr->ref_seq_span-1;
+
+ /* Sanity check */
+ if (s->ref_start < 0) {
+ fprintf(stderr, "Slice starts before base 1.\n");
+ s->ref_start = 0;
+ }
+ pthread_mutex_lock(&fd->ref_lock);
+ pthread_mutex_lock(&fd->refs->lock);
+ if ((fd->required_fields & SAM_SEQ) &&
+ s->ref_end > fd->refs->ref_id[ref_id]->length) {
+ s->ref_end = fd->refs->ref_id[ref_id]->length;
+ }
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+ }
+ }
+
+ if ((fd->required_fields & SAM_SEQ) &&
+ s->ref == NULL && s->hdr->ref_seq_id >= 0 && !fd->no_ref) {
+ fprintf(stderr, "Unable to fetch reference #%d %d..%d\n",
+ s->hdr->ref_seq_id, s->hdr->ref_seq_start,
+ s->hdr->ref_seq_start + s->hdr->ref_seq_span-1);
+ return -1;
+ }
+
+ if (CRAM_MAJOR_VERS(fd->version) != 1
+ && (fd->required_fields & SAM_SEQ)
+ && s->hdr->ref_seq_id >= 0
+ && !fd->ignore_md5
+ && memcmp(s->hdr->md5, "\0\0\0\0\0\0\0\0\0\0\0\0\0\0\0\0", 16)) {
+ hts_md5_context *md5;
+ unsigned char digest[16];
+
+ if (s->ref && s->hdr->ref_seq_id >= 0) {
+ int start, len;
+
+ if (s->hdr->ref_seq_start >= s->ref_start) {
+ start = s->hdr->ref_seq_start - s->ref_start;
+ } else {
+ fprintf(stderr, "Slice starts before base 1.\n");
+ start = 0;
+ }
+
+ if (s->hdr->ref_seq_span <= s->ref_end - s->ref_start + 1) {
+ len = s->hdr->ref_seq_span;
+ } else {
+ fprintf(stderr, "Slice ends beyond reference end.\n");
+ len = s->ref_end - s->ref_start + 1;
+ }
+
+ if (!(md5 = hts_md5_init()))
+ return -1;
+ if (start + len > s->ref_end - s->ref_start + 1)
+ len = s->ref_end - s->ref_start + 1 - start;
+ if (len >= 0)
+ hts_md5_update(md5, s->ref + start, len);
+ hts_md5_final(digest, md5);
+ hts_md5_destroy(md5);
+ } else if (!s->ref && s->hdr->ref_base_id >= 0) {
+ cram_block *b = cram_get_block_by_id(s, s->hdr->ref_base_id);
+ if (b) {
+ if (!(md5 = hts_md5_init()))
+ return -1;
+ hts_md5_update(md5, b->data, b->uncomp_size);
+ hts_md5_final(digest, md5);
+ hts_md5_destroy(md5);
+ }
+ }
+
+ if ((!s->ref && s->hdr->ref_base_id < 0)
+ || memcmp(digest, s->hdr->md5, 16) != 0) {
+ char M[33];
+ fprintf(stderr, "ERROR: md5sum reference mismatch for ref "
+ "%d pos %d..%d\n", ref_id, s->ref_start, s->ref_end);
+ fprintf(stderr, "CRAM: %s\n", md5_print(s->hdr->md5, M));
+ fprintf(stderr, "Ref : %s\n", md5_print(digest, M));
+ return -1;
+ }
+ }
+
+ if (ref_id == -2) {
+ pthread_mutex_lock(&fd->ref_lock);
+ pthread_mutex_lock(&fd->refs->lock);
+ refs = calloc(fd->refs->nref, sizeof(char *));
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+ if (!refs)
+ return -1;
+ }
+
+ int last_ref_id = -9; // Arbitrary -ve marker for not-yet-set
+ for (rec = 0; rec < s->hdr->num_records; rec++) {
+ cram_record *cr = &s->crecs[rec];
+ int has_MD, has_NM;
+
+ //fprintf(stderr, "Decode seq %d, %d/%d\n", rec, blk->byte, blk->bit);
+
+ cr->s = s;
+
+ out_sz = 1; /* decode 1 item */
+ if (ds & CRAM_BF) {
+ if (!c->comp_hdr->codecs[DS_BF]) return -1;
+ r |= c->comp_hdr->codecs[DS_BF]
+ ->decode(s, c->comp_hdr->codecs[DS_BF], blk,
+ (char *)&bf, &out_sz);
+ if (r || bf < 0 ||
+ bf >= sizeof(fd->bam_flag_swap)/sizeof(*fd->bam_flag_swap))
+ return -1;
+ bf = fd->bam_flag_swap[bf];
+ cr->flags = bf;
+ } else {
+ cr->flags = bf = 0x4; // unmapped
+ }
+
+ if (ds & CRAM_CF) {
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ /* CF is byte in 1.0, int32 in 2.0 */
+ if (!c->comp_hdr->codecs[DS_CF]) return -1;
+ r |= c->comp_hdr->codecs[DS_CF]
+ ->decode(s, c->comp_hdr->codecs[DS_CF], blk,
+ (char *)&cf, &out_sz);
+ if (r) return -1;
+ cr->cram_flags = cf;
+ } else {
+ if (!c->comp_hdr->codecs[DS_CF]) return -1;
+ r |= c->comp_hdr->codecs[DS_CF]
+ ->decode(s, c->comp_hdr->codecs[DS_CF], blk,
+ (char *)&cr->cram_flags, &out_sz);
+ if (r) return -1;
+ cf = cr->cram_flags;
+ }
+ } else {
+ cf = cr->cram_flags = 0;
+ }
+
+ if (CRAM_MAJOR_VERS(fd->version) != 1 && ref_id == -2) {
+ if (ds & CRAM_RI) {
+ if (!c->comp_hdr->codecs[DS_RI]) return -1;
+ r |= c->comp_hdr->codecs[DS_RI]
+ ->decode(s, c->comp_hdr->codecs[DS_RI], blk,
+ (char *)&cr->ref_id, &out_sz);
+ if (r) return -1;
+ if ((fd->required_fields & (SAM_SEQ|SAM_TLEN))
+ && cr->ref_id >= 0
+ && cr->ref_id != last_ref_id) {
+ if (!fd->no_ref) {
+ if (!refs[cr->ref_id])
+ refs[cr->ref_id] = cram_get_ref(fd, cr->ref_id,
+ 1, 0);
+ s->ref = refs[cr->ref_id];
+
+ if (!fd->unsorted && last_ref_id >= 0 && refs[last_ref_id]) {
+ cram_ref_decr(fd->refs, last_ref_id);
+ refs[last_ref_id] = NULL;
+ }
+ }
+ s->ref_start = 1;
+ pthread_mutex_lock(&fd->ref_lock);
+ pthread_mutex_lock(&fd->refs->lock);
+ s->ref_end = fd->refs->ref_id[cr->ref_id]->length;
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+
+ last_ref_id = cr->ref_id;
+ }
+ } else {
+ cr->ref_id = -1;
+ }
+ } else {
+ cr->ref_id = ref_id; // Forced constant in CRAM 1.0
+ }
+ if (cr->ref_id >= bfd->nref) {
+ fprintf(stderr, "Requested unknown reference ID %d\n", cr->ref_id);
+ return -1;
+ }
+
+ if (ds & CRAM_RL) {
+ if (!c->comp_hdr->codecs[DS_RL]) return -1;
+ r |= c->comp_hdr->codecs[DS_RL]
+ ->decode(s, c->comp_hdr->codecs[DS_RL], blk,
+ (char *)&cr->len, &out_sz);
+ if (r) return r;
+ if (cr->len < 0) {
+ fprintf(stderr, "Read has negative length\n");
+ return -1;
+ }
+ }
+
+ if (ds & CRAM_AP) {
+ if (!c->comp_hdr->codecs[DS_AP]) return -1;
+ r |= c->comp_hdr->codecs[DS_AP]
+ ->decode(s, c->comp_hdr->codecs[DS_AP], blk,
+ (char *)&cr->apos, &out_sz);
+ if (r) return r;
+ if (c->comp_hdr->AP_delta)
+ cr->apos += s->last_apos;
+ s->last_apos= cr->apos;
+ } else {
+ cr->apos = c->ref_seq_start;
+ }
+
+ if (ds & CRAM_RG) {
+ if (!c->comp_hdr->codecs[DS_RG]) return -1;
+ r |= c->comp_hdr->codecs[DS_RG]
+ ->decode(s, c->comp_hdr->codecs[DS_RG], blk,
+ (char *)&cr->rg, &out_sz);
+ if (r) return r;
+ if (cr->rg == unknown_rg)
+ cr->rg = -1;
+ } else {
+ cr->rg = -1;
+ }
+
+ cr->name_len = 0;
+
+ if (c->comp_hdr->read_names_included) {
+ int32_t out_sz2 = 1;
+
+ // Read directly into name cram_block
+ cr->name = BLOCK_SIZE(s->name_blk);
+ if (ds & CRAM_RN) {
+ if (!c->comp_hdr->codecs[DS_RN]) return -1;
+ r |= c->comp_hdr->codecs[DS_RN]
+ ->decode(s, c->comp_hdr->codecs[DS_RN], blk,
+ (char *)s->name_blk, &out_sz2);
+ if (r) return r;
+ cr->name_len = out_sz2;
+ }
+ }
+
+ cr->mate_pos = 0;
+ cr->mate_line = -1;
+ cr->mate_ref_id = -1;
+ if ((ds & CRAM_CF) && (cf & CRAM_FLAG_DETACHED)) {
+ if (ds & CRAM_MF) {
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ /* MF is byte in 1.0, int32 in 2.0 */
+ unsigned char mf;
+ if (!c->comp_hdr->codecs[DS_MF]) return -1;
+ r |= c->comp_hdr->codecs[DS_MF]
+ ->decode(s, c->comp_hdr->codecs[DS_MF],
+ blk, (char *)&mf, &out_sz);
+ if (r) return r;
+ cr->mate_flags = mf;
+ } else {
+ if (!c->comp_hdr->codecs[DS_MF]) return -1;
+ r |= c->comp_hdr->codecs[DS_MF]
+ ->decode(s, c->comp_hdr->codecs[DS_MF],
+ blk,
+ (char *)&cr->mate_flags,
+ &out_sz);
+ if (r) return r;
+ }
+ } else {
+ cr->mate_flags = 0;
+ }
+
+ if (!c->comp_hdr->read_names_included) {
+ int32_t out_sz2 = 1;
+
+ // Read directly into name cram_block
+ cr->name = BLOCK_SIZE(s->name_blk);
+ if (ds & CRAM_RN) {
+ if (!c->comp_hdr->codecs[DS_RN]) return -1;
+ r |= c->comp_hdr->codecs[DS_RN]
+ ->decode(s, c->comp_hdr->codecs[DS_RN],
+ blk, (char *)s->name_blk,
+ &out_sz2);
+ if (r) return r;
+ cr->name_len = out_sz2;
+ }
+ }
+
+ if (ds & CRAM_NS) {
+ if (!c->comp_hdr->codecs[DS_NS]) return -1;
+ r |= c->comp_hdr->codecs[DS_NS]
+ ->decode(s, c->comp_hdr->codecs[DS_NS], blk,
+ (char *)&cr->mate_ref_id, &out_sz);
+ if (r) return r;
+ }
+
+// Skip as mate_ref of "*" is legit. It doesn't mean unmapped, just unknown.
+// if (cr->mate_ref_id == -1 && cr->flags & 0x01) {
+// /* Paired, but unmapped */
+// cr->flags |= BAM_FMUNMAP;
+// }
+
+ if (ds & CRAM_NP) {
+ if (!c->comp_hdr->codecs[DS_NP]) return -1;
+ r |= c->comp_hdr->codecs[DS_NP]
+ ->decode(s, c->comp_hdr->codecs[DS_NP], blk,
+ (char *)&cr->mate_pos, &out_sz);
+ if (r) return r;
+ }
+
+ if (ds & CRAM_TS) {
+ if (!c->comp_hdr->codecs[DS_TS]) return -1;
+ r |= c->comp_hdr->codecs[DS_TS]
+ ->decode(s, c->comp_hdr->codecs[DS_TS], blk,
+ (char *)&cr->tlen, &out_sz);
+ if (r) return r;
+ } else {
+ cr->tlen = INT_MIN;
+ }
+ } else if ((ds & CRAM_CF) && (cf & CRAM_FLAG_MATE_DOWNSTREAM)) {
+ if (ds & CRAM_NF) {
+ if (!c->comp_hdr->codecs[DS_NF]) return -1;
+ r |= c->comp_hdr->codecs[DS_NF]
+ ->decode(s, c->comp_hdr->codecs[DS_NF], blk,
+ (char *)&cr->mate_line, &out_sz);
+ if (r) return r;
+ cr->mate_line += rec + 1;
+
+ //cr->name_len = sprintf(name, "%d", name_id++);
+ //cr->name = DSTRING_LEN(name_ds);
+ //dstring_nappend(name_ds, name, cr->name_len);
+
+ cr->mate_ref_id = -1;
+ cr->tlen = INT_MIN;
+ cr->mate_pos = 0;
+ } else {
+ cr->mate_flags = 0;
+ cr->tlen = INT_MIN;
+ }
+ } else {
+ cr->mate_flags = 0;
+ cr->tlen = INT_MIN;
+ }
+ /*
+ else if (!name[0]) {
+ //name[0] = '?'; name[1] = 0;
+ //cr->name_len = 1;
+ //cr->name= DSTRING_LEN(s->name_ds);
+ //dstring_nappend(s->name_ds, "?", 1);
+
+ cr->mate_ref_id = -1;
+ cr->tlen = 0;
+ cr->mate_pos = 0;
+ }
+ */
+
+ /* Auxiliary tags */
+ has_MD = has_NM = 0;
+ if (CRAM_MAJOR_VERS(fd->version) == 1)
+ r |= cram_decode_aux_1_0(c, s, blk, cr);
+ else
+ r |= cram_decode_aux(c, s, blk, cr, &has_MD, &has_NM);
+ if (r) return r;
+
+ /* Fake up dynamic string growth and appending */
+ if (ds & CRAM_RL) {
+ cr->seq = BLOCK_SIZE(s->seqs_blk);
+ BLOCK_GROW(s->seqs_blk, cr->len);
+ seq = (char *)BLOCK_END(s->seqs_blk);
+ BLOCK_SIZE(s->seqs_blk) += cr->len;
+
+ if (!seq)
+ return -1;
+
+ cr->qual = BLOCK_SIZE(s->qual_blk);
+ BLOCK_GROW(s->qual_blk, cr->len);
+ qual = (char *)BLOCK_END(s->qual_blk);
+ BLOCK_SIZE(s->qual_blk) += cr->len;
+
+ if (!s->ref)
+ memset(seq, '=', cr->len);
+ }
+
+ if (!(bf & BAM_FUNMAP)) {
+ if ((ds & CRAM_AP) && cr->apos <= 0) {
+ fprintf(stderr,
+ "Read has alignment position %d but no unmapped flag\n",
+ cr->apos);
+ return -1;
+ }
+ /* Decode sequence and generate CIGAR */
+ if (ds & (CRAM_SEQ | CRAM_MQ)) {
+ r |= cram_decode_seq(fd, c, s, blk, cr, bfd, cf, seq, qual,
+ has_MD, has_NM);
+ if (r) return r;
+ } else {
+ cr->cigar = 0;
+ cr->ncigar = 0;
+ cr->aend = cr->apos;
+ cr->mqual = 0;
+ }
+ } else {
+ int out_sz2 = cr->len;
+
+ //puts("Unmapped");
+ cr->cigar = 0;
+ cr->ncigar = 0;
+ cr->aend = cr->apos;
+ cr->mqual = 0;
+
+ if (ds & CRAM_BA && cr->len) {
+ if (!c->comp_hdr->codecs[DS_BA]) return -1;
+ r |= c->comp_hdr->codecs[DS_BA]
+ ->decode(s, c->comp_hdr->codecs[DS_BA], blk,
+ (char *)seq, &out_sz2);
+ if (r) return r;
+ }
+
+ if ((ds & CRAM_CF) && (cf & CRAM_FLAG_PRESERVE_QUAL_SCORES)) {
+ out_sz2 = cr->len;
+ if (ds & CRAM_QS && cr->len >= 0) {
+ if (!c->comp_hdr->codecs[DS_QS]) return -1;
+ r |= c->comp_hdr->codecs[DS_QS]
+ ->decode(s, c->comp_hdr->codecs[DS_QS],
+ blk, qual, &out_sz2);
+ if (r) return r;
+ }
+ } else {
+ if (ds & CRAM_RL)
+ memset(qual, 255, cr->len);
+ }
+ }
+ }
+
+ pthread_mutex_lock(&fd->ref_lock);
+ if (refs) {
+ int i;
+ for (i = 0; i < fd->refs->nref; i++) {
+ if (refs[i])
+ cram_ref_decr(fd->refs, i);
+ }
+ free(refs);
+ } else if (ref_id >= 0 && s->ref != fd->ref_free && !embed_ref) {
+ cram_ref_decr(fd->refs, ref_id);
+ }
+ pthread_mutex_unlock(&fd->ref_lock);
+
+ /* Resolve mate pair cross-references between recs within this slice */
+ r |= cram_decode_slice_xref(s, fd->required_fields);
+
+ // Free the original blocks as we no longer need these.
+ {
+ int i;
+ for (i = 0; i < s->hdr->num_blocks; i++) {
+ cram_block *b = s->block[i];
+ cram_free_block(b);
+ s->block[i] = NULL;
+ }
+ }
+
+ // Also see initial BLOCK_RESIZE_EXACT at top of function.
+ // As we grow blocks we overallocate by up to 50%. So shrink
+ // back to their final sizes here.
+ //
+// fprintf(stderr, "%d %d // %d %d // %d %d // %d %d\n",
+// (int)s->seqs_blk->byte, (int)s->seqs_blk->alloc,
+// (int)s->qual_blk->byte, (int)s->qual_blk->alloc,
+// (int)s->name_blk->byte, (int)s->name_blk->alloc,
+// (int)s->aux_blk->byte, (int)s->aux_blk->alloc);
+ BLOCK_RESIZE_EXACT(s->seqs_blk, BLOCK_SIZE(s->seqs_blk)+1);
+ BLOCK_RESIZE_EXACT(s->qual_blk, BLOCK_SIZE(s->qual_blk)+1);
+ BLOCK_RESIZE_EXACT(s->name_blk, BLOCK_SIZE(s->name_blk)+1);
+ BLOCK_RESIZE_EXACT(s->aux_blk, BLOCK_SIZE(s->aux_blk)+1);
+
+ return r;
+}
+
+typedef struct {
+ cram_fd *fd;
+ cram_container *c;
+ cram_slice *s;
+ SAM_hdr *h;
+ int exit_code;
+} cram_decode_job;
+
+void *cram_decode_slice_thread(void *arg) {
+ cram_decode_job *j = (cram_decode_job *)arg;
+
+ j->exit_code = cram_decode_slice(j->fd, j->c, j->s, j->h);
+
+ return j;
+}
+
+/*
+ * Spawn a multi-threaded version of cram_decode_slice().
+ */
+int cram_decode_slice_mt(cram_fd *fd, cram_container *c, cram_slice *s,
+ SAM_hdr *bfd) {
+ cram_decode_job *j;
+ int nonblock;
+
+ if (!fd->pool)
+ return cram_decode_slice(fd, c, s, bfd);
+
+ if (!(j = malloc(sizeof(*j))))
+ return -1;
+
+ j->fd = fd;
+ j->c = c;
+ j->s = s;
+ j->h = bfd;
+
+ nonblock = t_pool_results_queue_sz(fd->rqueue) ? 1 : 0;
+
+ if (-1 == t_pool_dispatch2(fd->pool, fd->rqueue, cram_decode_slice_thread,
+ j, nonblock)) {
+ /* Would block */
+ fd->job_pending = j;
+ } else {
+ fd->job_pending = NULL;
+ }
+
+ // flush too
+ return 0;
+}
+
+
+/* ----------------------------------------------------------------------
+ * CRAM sequence iterators.
+ */
+
+/*
+ * Converts a cram in-memory record into a bam in-memory record. We
+ * pass a pointer to a bam_seq_t pointer along with the a pointer to
+ * the allocated size. These can initially be pointers to NULL and zero.
+ *
+ * This function will reallocate the bam buffer as required and update
+ * (*bam)->alloc accordingly, allowing it to be used within a loop
+ * efficiently without needing to allocate new bam objects over and
+ * over again.
+ *
+ * Returns the used size of the bam record on success
+ * -1 on failure.
+ */
+static int cram_to_bam(SAM_hdr *bfd, cram_fd *fd, cram_slice *s,
+ cram_record *cr, int rec, bam_seq_t **bam) {
+ int bam_idx, rg_len;
+ char name_a[1024], *name;
+ int name_len;
+ char *aux, *aux_orig;
+ char *seq, *qual;
+
+ /* Assign names if not explicitly set */
+ if (fd->required_fields & SAM_QNAME) {
+ if (cr->name_len) {
+ name = (char *)BLOCK_DATA(s->name_blk) + cr->name;
+ name_len = cr->name_len;
+ } else {
+ name = name_a;
+ name_len = strlen(fd->prefix);
+ memcpy(name, fd->prefix, name_len);
+ name += name_len;
+ *name++ = ':';
+ if (cr->mate_line >= 0 && cr->mate_line < rec)
+ name = (char *)append_uint64((unsigned char *)name,
+ s->hdr->record_counter +
+ cr->mate_line + 1);
+ else
+ name = (char *)append_uint64((unsigned char *)name,
+ s->hdr->record_counter +
+ rec + 1);
+ name_len = name - name_a;
+ name = name_a;
+ }
+ } else {
+ name = "?";
+ name_len = 1;
+ }
+
+ /* Generate BAM record */
+ if (cr->rg < -1 || cr->rg >= bfd->nrg)
+ return -1;
+ rg_len = (cr->rg != -1) ? bfd->rg[cr->rg].name_len + 4 : 0;
+
+ if (fd->required_fields & (SAM_SEQ | SAM_QUAL)) {
+ if (!BLOCK_DATA(s->seqs_blk))
+ return -1;
+ seq = (char *)BLOCK_DATA(s->seqs_blk) + cr->seq;
+ } else {
+ seq = "*";
+ cr->len = 0;
+ }
+
+
+ if (fd->required_fields & SAM_QUAL) {
+ if (!BLOCK_DATA(s->qual_blk))
+ return -1;
+ qual = (char *)BLOCK_DATA(s->qual_blk) + cr->qual;
+ } else {
+ qual = NULL;
+ }
+
+ bam_idx = bam_construct_seq(bam, cr->aux_size + rg_len,
+ name, name_len,
+ cr->flags,
+ cr->ref_id,
+ cr->apos,
+ cr->aend,
+ cr->mqual,
+ cr->ncigar, &s->cigar[cr->cigar],
+ cr->mate_ref_id,
+ cr->mate_pos,
+ cr->tlen,
+ cr->len,
+ seq,
+ qual);
+ if (bam_idx == -1)
+ return -1;
+
+ aux = aux_orig = (char *)bam_aux(*bam);
+
+ /* Auxiliary strings */
+ if (cr->aux_size != 0) {
+ memcpy(aux, BLOCK_DATA(s->aux_blk) + cr->aux, cr->aux_size);
+ aux += cr->aux_size;
+ }
+
+ /* RG:Z: */
+ if (cr->rg != -1) {
+ int len = bfd->rg[cr->rg].name_len;
+ *aux++ = 'R'; *aux++ = 'G'; *aux++ = 'Z';
+ memcpy(aux, bfd->rg[cr->rg].name, len);
+ aux += len;
+ *aux++ = 0;
+ }
+
+ return bam_idx + (aux - aux_orig);
+}
+
+/*
+ * Here be dragons! The multi-threading code in this is crufty beyond belief.
+ */
+static cram_slice *cram_next_slice(cram_fd *fd, cram_container **cp) {
+ cram_container *c;
+ cram_slice *s = NULL;
+
+ if (!(c = fd->ctr)) {
+ // Load first container.
+ do {
+ if (!(c = fd->ctr = cram_read_container(fd)))
+ return NULL;
+ } while (c->length == 0);
+
+ /*
+ * The first container may be a result of a sub-range query.
+ * In which case it may still not be the optimal starting point
+ * due to skipped containers/slices in the index.
+ */
+ if (fd->range.refid != -2) {
+ while (c->ref_seq_id != -2 &&
+ (c->ref_seq_id < fd->range.refid ||
+ c->ref_seq_start + c->ref_seq_span-1 < fd->range.start)) {
+ if (0 != cram_seek(fd, c->length, SEEK_CUR))
+ return NULL;
+ cram_free_container(fd->ctr);
+ do {
+ if (!(c = fd->ctr = cram_read_container(fd)))
+ return NULL;
+ } while (c->length == 0);
+ }
+
+ if (c->ref_seq_id != -2 && c->ref_seq_id != fd->range.refid)
+ return NULL;
+ }
+
+ if (!(c->comp_hdr_block = cram_read_block(fd)))
+ return NULL;
+ if (c->comp_hdr_block->content_type != COMPRESSION_HEADER)
+ return NULL;
+
+ c->comp_hdr = cram_decode_compression_header(fd, c->comp_hdr_block);
+ if (!c->comp_hdr)
+ return NULL;
+ if (!c->comp_hdr->AP_delta &&
+ sam_hdr_sort_order(fd->header) != ORDER_COORD) {
+ pthread_mutex_lock(&fd->ref_lock);
+ fd->unsorted = 1;
+ pthread_mutex_unlock(&fd->ref_lock);
+ }
+ }
+
+ if ((s = c->slice)) {
+ c->slice = NULL;
+ cram_free_slice(s);
+ s = NULL;
+ }
+
+ if (c->curr_slice == c->max_slice) {
+ cram_free_container(c);
+ c = NULL;
+ }
+
+ /* Sorry this is so contorted! */
+ for (;;) {
+ if (fd->job_pending) {
+ cram_decode_job *j = (cram_decode_job *)fd->job_pending;
+ c = j->c;
+ s = j->s;
+ free(fd->job_pending);
+ fd->job_pending = NULL;
+ } else if (!fd->ooc) {
+ empty_container:
+ if (!c || c->curr_slice == c->max_slice) {
+ // new container
+ do {
+ if (!(c = fd->ctr = cram_read_container(fd))) {
+ if (fd->pool) {
+ fd->ooc = 1;
+ break;
+ }
+
+ return NULL;
+ }
+ } while (c->length == 0);
+ if (fd->ooc)
+ break;
+
+ /* Skip containers not yet spanning our range */
+ if (fd->range.refid != -2 && c->ref_seq_id != -2) {
+ fd->required_fields |= SAM_POS;
+
+ if (c->ref_seq_id != fd->range.refid) {
+ cram_free_container(c);
+ fd->ctr = NULL;
+ fd->ooc = 1;
+ fd->eof = 1;
+ break;
+ }
+
+ if (c->ref_seq_start > fd->range.end) {
+ cram_free_container(c);
+ fd->ctr = NULL;
+ fd->ooc = 1;
+ fd->eof = 1;
+ break;
+ }
+
+ if (c->ref_seq_start + c->ref_seq_span-1 <
+ fd->range.start) {
+ c->curr_rec = c->max_rec;
+ c->curr_slice = c->max_slice;
+ cram_seek(fd, c->length, SEEK_CUR);
+ cram_free_container(c);
+ c = NULL;
+ continue;
+ }
+ }
+
+ if (!(c->comp_hdr_block = cram_read_block(fd)))
+ return NULL;
+ if (c->comp_hdr_block->content_type != COMPRESSION_HEADER)
+ return NULL;
+
+ c->comp_hdr =
+ cram_decode_compression_header(fd, c->comp_hdr_block);
+ if (!c->comp_hdr)
+ return NULL;
+
+ if (!c->comp_hdr->AP_delta &&
+ sam_hdr_sort_order(fd->header) != ORDER_COORD) {
+ pthread_mutex_lock(&fd->ref_lock);
+ fd->unsorted = 1;
+ pthread_mutex_unlock(&fd->ref_lock);
+ }
+ }
+
+ if (c->num_records == 0) {
+ cram_free_container(c); c = NULL;
+ goto empty_container;
+ }
+
+
+ if (!(s = c->slice = cram_read_slice(fd)))
+ return NULL;
+ c->curr_slice++;
+ c->curr_rec = 0;
+ c->max_rec = s->hdr->num_records;
+
+ s->last_apos = s->hdr->ref_seq_start;
+
+ /* Skip slices not yet spanning our range */
+ if (fd->range.refid != -2 && s->hdr->ref_seq_id != -2) {
+ if (s->hdr->ref_seq_id != fd->range.refid) {
+ fd->eof = 1;
+ cram_free_slice(s);
+ c->slice = NULL;
+ return NULL;
+ }
+
+ if (s->hdr->ref_seq_start > fd->range.end) {
+ fd->eof = 1;
+ cram_free_slice(s);
+ c->slice = NULL;
+ return NULL;
+ }
+
+ if (s->hdr->ref_seq_start + s->hdr->ref_seq_span-1 <
+ fd->range.start) {
+ cram_free_slice(s);
+ c->slice = NULL;
+ cram_free_container(c);
+ c = NULL;
+ continue;
+ }
+ }
+ }
+
+ /* Test decoding of 1st seq */
+ if (!c || !s)
+ break;
+
+ if (cram_decode_slice_mt(fd, c, s, fd->header) != 0) {
+ // if (cram_decode_slice(fd, c, s, fd->header) != 0) {
+ fprintf(stderr, "Failure to decode slice\n");
+ cram_free_slice(s);
+ c->slice = NULL;
+ return NULL;
+ }
+
+ if (!fd->pool || fd->job_pending)
+ break;
+
+ // Push it a bit far, to qsize in queue rather than pending arrival,
+ // as cram tends to be a bit bursty in decode timings.
+ if (t_pool_results_queue_len(fd->rqueue) > fd->pool->qsize)
+ break;
+ }
+
+ if (fd->pool) {
+ t_pool_result *res;
+ cram_decode_job *j;
+
+// fprintf(stderr, "Thread pool len = %d, %d\n",
+// t_pool_results_queue_len(fd->rqueue),
+// t_pool_results_queue_sz(fd->rqueue));
+
+ if (fd->ooc && t_pool_results_queue_empty(fd->rqueue))
+ return NULL;
+
+ res = t_pool_next_result_wait(fd->rqueue);
+
+ if (!res || !res->data) {
+ fprintf(stderr, "t_pool_next_result failure\n");
+ return NULL;
+ }
+
+ j = (cram_decode_job *)res->data;
+ c = j->c;
+ s = j->s;
+
+ fd->ctr = c;
+
+ t_pool_delete_result(res, 1);
+ }
+
+ *cp = c;
+ return s;
+}
+
+/*
+ * Read the next cram record and return it.
+ * Note that to decode cram_record the caller will need to look up some data
+ * in the current slice, pointed to by fd->ctr->slice. This is valid until
+ * the next call to cram_get_seq (which may invalidate it).
+ *
+ * Returns record pointer on success (do not free)
+ * NULL on failure
+ */
+cram_record *cram_get_seq(cram_fd *fd) {
+ cram_container *c;
+ cram_slice *s;
+
+ for (;;) {
+ c = fd->ctr;
+ if (c && c->slice && c->curr_rec < c->max_rec) {
+ s = c->slice;
+ } else {
+ if (!(s = cram_next_slice(fd, &c)))
+ return NULL;
+ continue; /* In case slice contains no records */
+ }
+
+ if (fd->range.refid != -2) {
+ if (fd->range.refid == -1 && s->crecs[c->curr_rec].ref_id != -1) {
+ // Special case when looking for unmapped blocks at end.
+ // If these are mixed in with mapped data (c->ref_id == -2)
+ // then we need skip until we find the unmapped data, if at all
+ c->curr_rec++;
+ continue;
+ }
+ if (s->crecs[c->curr_rec].ref_id < fd->range.refid &&
+ s->crecs[c->curr_rec].ref_id != -1) {
+ // Looking for a mapped read, but not there yet. Special case
+ // as -1 (unmapped) shouldn't be considered < refid.
+ c->curr_rec++;
+ continue;
+ }
+
+ if (s->crecs[c->curr_rec].ref_id != fd->range.refid) {
+ fd->eof = 1;
+ cram_free_slice(s);
+ c->slice = NULL;
+ return NULL;
+ }
+
+ if (fd->range.refid != -1 && s->crecs[c->curr_rec].apos > fd->range.end) {
+ fd->eof = 1;
+ cram_free_slice(s);
+ c->slice = NULL;
+ return NULL;
+ }
+
+ if (fd->range.refid != -1 && s->crecs[c->curr_rec].aend < fd->range.start) {
+ c->curr_rec++;
+ continue;
+ }
+ }
+
+ break;
+ }
+
+ fd->ctr = c;
+ c->slice = s;
+ return &s->crecs[c->curr_rec++];
+}
+
+/*
+ * Read the next cram record and convert it to a bam_seq_t struct.
+ *
+ * Returns 0 on success
+ * -1 on EOF or failure (check fd->err)
+ */
+int cram_get_bam_seq(cram_fd *fd, bam_seq_t **bam) {
+ cram_record *cr;
+ cram_container *c;
+ cram_slice *s;
+
+ if (!(cr = cram_get_seq(fd)))
+ return -1;
+
+ c = fd->ctr;
+ s = c->slice;
+
+ return cram_to_bam(fd->header, fd, s, cr, c->curr_rec-1, bam);
+}
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*! \file
+ * Include cram.h instead.
+ *
+ * This is an internal part of the CRAM system and is automatically included
+ * when you #include cram.h.
+ *
+ * Implements the decoding portion of CRAM I/O. Also see
+ * cram_codecs.[ch] for the actual encoding functions themselves.
+ */
+
+#ifndef _CRAM_READ_H_
+#define _CRAM_READ_H_
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/* ----------------------------------------------------------------------
+ * CRAM sequence iterators.
+ */
+
+/*! Read the next cram record and return it as a cram_record.
+ *
+ * Note that to decode cram_record the caller will need to look up some data
+ * in the current slice, pointed to by fd->ctr->slice. This is valid until
+ * the next call to cram_get_seq (which may invalidate it).
+ *
+ * @return
+ * Returns record pointer on success (do not free);
+ * NULL on failure
+ */
+cram_record *cram_get_seq(cram_fd *fd);
+
+/*! Read the next cram record and convert it to a bam_seq_t struct.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on EOF or failure (check fd->err)
+ */
+int cram_get_bam_seq(cram_fd *fd, bam_seq_t **bam);
+
+
+/* ----------------------------------------------------------------------
+ * Internal functions
+ */
+
+/*! INTERNAL:
+ * Decodes a CRAM block compression header.
+ *
+ * @return
+ * Returns header ptr on success;
+ * NULL on failure
+ */
+cram_block_compression_hdr *cram_decode_compression_header(cram_fd *fd,
+ cram_block *b);
+
+/*! INTERNAL:
+ * Decodes a CRAM (un)mapped slice header block.
+ *
+ * @return
+ * Returns slice header ptr on success;
+ * NULL on failure
+ */
+cram_block_slice_hdr *cram_decode_slice_header(cram_fd *fd, cram_block *b);
+
+
+/*! INTERNAL:
+ * Decode an entire slice from container blocks. Fills out s->crecs[] array.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_decode_slice(cram_fd *fd, cram_container *c, cram_slice *s,
+ SAM_hdr *hdr);
+
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <stdio.h>
+#include <errno.h>
+#include <assert.h>
+#include <stdlib.h>
+#include <string.h>
+#include <zlib.h>
+#include <sys/types.h>
+#include <sys/stat.h>
+#include <math.h>
+#include <ctype.h>
+
+#include "cram/cram.h"
+#include "cram/os.h"
+#include "htslib/hts.h"
+
+#define Z_CRAM_STRAT Z_FILTERED
+//#define Z_CRAM_STRAT Z_RLE
+//#define Z_CRAM_STRAT Z_HUFFMAN_ONLY
+//#define Z_CRAM_STRAT Z_DEFAULT_STRATEGY
+
+static int process_one_read(cram_fd *fd, cram_container *c,
+ cram_slice *s, cram_record *cr,
+ bam_seq_t *b, int rnum);
+
+/*
+ * Returns index of val into key.
+ * Basically strchr(key, val)-key;
+ */
+static int sub_idx(char *key, char val) {
+ int i;
+
+ for (i = 0; *key && *key++ != val; i++);
+ return i;
+}
+
+/*
+ * Encodes a compression header block into a generic cram_block structure.
+ *
+ * Returns cram_block ptr on success
+ * NULL on failure
+ */
+cram_block *cram_encode_compression_header(cram_fd *fd, cram_container *c,
+ cram_block_compression_hdr *h) {
+ cram_block *cb = cram_new_block(COMPRESSION_HEADER, 0);
+ cram_block *map = cram_new_block(COMPRESSION_HEADER, 0);
+ int i, mc;
+
+ if (!cb || !map)
+ return NULL;
+
+ /*
+ * This is a concatenation of several blocks of data:
+ * header + landmarks, preservation map, read encoding map, and the tag
+ * encoding map.
+ * All 4 are variable sized and we need to know how large these are
+ * before creating the compression header itself as this starts with
+ * the total size (stored as a variable length string).
+ */
+
+ // Duplicated from container itself, and removed in 1.1
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ itf8_put_blk(cb, h->ref_seq_id);
+ itf8_put_blk(cb, h->ref_seq_start);
+ itf8_put_blk(cb, h->ref_seq_span);
+ itf8_put_blk(cb, h->num_records);
+ itf8_put_blk(cb, h->num_landmarks);
+ for (i = 0; i < h->num_landmarks; i++) {
+ itf8_put_blk(cb, h->landmark[i]);
+ }
+ }
+
+ if (h->preservation_map)
+ kh_destroy(map, h->preservation_map);
+
+ /* Create in-memory preservation map */
+ /* FIXME: should create this when we create the container */
+ {
+ khint_t k;
+ int r;
+
+ if (!(h->preservation_map = kh_init(map)))
+ return NULL;
+
+ k = kh_put(map, h->preservation_map, "RN", &r);
+ if (-1 == r) return NULL;
+ kh_val(h->preservation_map, k).i = 1;
+
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ k = kh_put(map, h->preservation_map, "PI", &r);
+ if (-1 == r) return NULL;
+ kh_val(h->preservation_map, k).i = 0;
+
+ k = kh_put(map, h->preservation_map, "UI", &r);
+ if (-1 == r) return NULL;
+ kh_val(h->preservation_map, k).i = 1;
+
+ k = kh_put(map, h->preservation_map, "MI", &r);
+ if (-1 == r) return NULL;
+ kh_val(h->preservation_map, k).i = 1;
+
+ } else {
+ // Technically SM was in 1.0, but wasn't in Java impl.
+ k = kh_put(map, h->preservation_map, "SM", &r);
+ if (-1 == r) return NULL;
+ kh_val(h->preservation_map, k).i = 0;
+
+ k = kh_put(map, h->preservation_map, "TD", &r);
+ if (-1 == r) return NULL;
+ kh_val(h->preservation_map, k).i = 0;
+
+ k = kh_put(map, h->preservation_map, "AP", &r);
+ if (-1 == r) return NULL;
+ kh_val(h->preservation_map, k).i = h->AP_delta;
+
+ if (fd->no_ref || fd->embed_ref) {
+ // Reference Required == No
+ k = kh_put(map, h->preservation_map, "RR", &r);
+ if (-1 == r) return NULL;
+ kh_val(h->preservation_map, k).i = 0;
+ }
+ }
+ }
+
+ /* Encode preservation map; could collapse this and above into one */
+ mc = 0;
+ BLOCK_SIZE(map) = 0;
+ if (h->preservation_map) {
+ khint_t k;
+
+ for (k = kh_begin(h->preservation_map);
+ k != kh_end(h->preservation_map);
+ k++) {
+ const char *key;
+ khash_t(map) *pmap = h->preservation_map;
+
+
+ if (!kh_exist(pmap, k))
+ continue;
+
+ key = kh_key(pmap, k);
+ BLOCK_APPEND(map, key, 2);
+
+ switch(CRAM_KEY(key[0], key[1])) {
+ case CRAM_KEY('M','I'):
+ BLOCK_APPEND_CHAR(map, kh_val(pmap, k).i);
+ break;
+
+ case CRAM_KEY('U','I'):
+ BLOCK_APPEND_CHAR(map, kh_val(pmap, k).i);
+ break;
+
+ case CRAM_KEY('P','I'):
+ BLOCK_APPEND_CHAR(map, kh_val(pmap, k).i);
+ break;
+
+ case CRAM_KEY('A','P'):
+ BLOCK_APPEND_CHAR(map, kh_val(pmap, k).i);
+ break;
+
+ case CRAM_KEY('R','N'):
+ BLOCK_APPEND_CHAR(map, kh_val(pmap, k).i);
+ break;
+
+ case CRAM_KEY('R','R'):
+ BLOCK_APPEND_CHAR(map, kh_val(pmap, k).i);
+ break;
+
+ case CRAM_KEY('S','M'): {
+ char smat[5], *mp = smat;
+ *mp++ =
+ (sub_idx("CGTN", h->substitution_matrix[0][0]) << 6) |
+ (sub_idx("CGTN", h->substitution_matrix[0][1]) << 4) |
+ (sub_idx("CGTN", h->substitution_matrix[0][2]) << 2) |
+ (sub_idx("CGTN", h->substitution_matrix[0][3]) << 0);
+ *mp++ =
+ (sub_idx("AGTN", h->substitution_matrix[1][0]) << 6) |
+ (sub_idx("AGTN", h->substitution_matrix[1][1]) << 4) |
+ (sub_idx("AGTN", h->substitution_matrix[1][2]) << 2) |
+ (sub_idx("AGTN", h->substitution_matrix[1][3]) << 0);
+ *mp++ =
+ (sub_idx("ACTN", h->substitution_matrix[2][0]) << 6) |
+ (sub_idx("ACTN", h->substitution_matrix[2][1]) << 4) |
+ (sub_idx("ACTN", h->substitution_matrix[2][2]) << 2) |
+ (sub_idx("ACTN", h->substitution_matrix[2][3]) << 0);
+ *mp++ =
+ (sub_idx("ACGN", h->substitution_matrix[3][0]) << 6) |
+ (sub_idx("ACGN", h->substitution_matrix[3][1]) << 4) |
+ (sub_idx("ACGN", h->substitution_matrix[3][2]) << 2) |
+ (sub_idx("ACGN", h->substitution_matrix[3][3]) << 0);
+ *mp++ =
+ (sub_idx("ACGT", h->substitution_matrix[4][0]) << 6) |
+ (sub_idx("ACGT", h->substitution_matrix[4][1]) << 4) |
+ (sub_idx("ACGT", h->substitution_matrix[4][2]) << 2) |
+ (sub_idx("ACGT", h->substitution_matrix[4][3]) << 0);
+ BLOCK_APPEND(map, smat, 5);
+ break;
+ }
+
+ case CRAM_KEY('T','D'): {
+ itf8_put_blk(map, BLOCK_SIZE(h->TD_blk));
+ BLOCK_APPEND(map,
+ BLOCK_DATA(h->TD_blk),
+ BLOCK_SIZE(h->TD_blk));
+ break;
+ }
+
+ default:
+ fprintf(stderr, "Unknown preservation key '%.2s'\n", key);
+ break;
+ }
+
+ mc++;
+ }
+ }
+ itf8_put_blk(cb, BLOCK_SIZE(map) + itf8_size(mc));
+ itf8_put_blk(cb, mc);
+ BLOCK_APPEND(cb, BLOCK_DATA(map), BLOCK_SIZE(map));
+
+ /* rec encoding map */
+ mc = 0;
+ BLOCK_SIZE(map) = 0;
+ if (h->codecs[DS_BF]) {
+ if (-1 == h->codecs[DS_BF]->store(h->codecs[DS_BF], map, "BF",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_CF]) {
+ if (-1 == h->codecs[DS_CF]->store(h->codecs[DS_CF], map, "CF",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_RL]) {
+ if (-1 == h->codecs[DS_RL]->store(h->codecs[DS_RL], map, "RL",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_AP]) {
+ if (-1 == h->codecs[DS_AP]->store(h->codecs[DS_AP], map, "AP",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_RG]) {
+ if (-1 == h->codecs[DS_RG]->store(h->codecs[DS_RG], map, "RG",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_MF]) {
+ if (-1 == h->codecs[DS_MF]->store(h->codecs[DS_MF], map, "MF",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_NS]) {
+ if (-1 == h->codecs[DS_NS]->store(h->codecs[DS_NS], map, "NS",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_NP]) {
+ if (-1 == h->codecs[DS_NP]->store(h->codecs[DS_NP], map, "NP",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_TS]) {
+ if (-1 == h->codecs[DS_TS]->store(h->codecs[DS_TS], map, "TS",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_NF]) {
+ if (-1 == h->codecs[DS_NF]->store(h->codecs[DS_NF], map, "NF",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_TC]) {
+ if (-1 == h->codecs[DS_TC]->store(h->codecs[DS_TC], map, "TC",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_TN]) {
+ if (-1 == h->codecs[DS_TN]->store(h->codecs[DS_TN], map, "TN",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_TL]) {
+ if (-1 == h->codecs[DS_TL]->store(h->codecs[DS_TL], map, "TL",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_FN]) {
+ if (-1 == h->codecs[DS_FN]->store(h->codecs[DS_FN], map, "FN",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_FC]) {
+ if (-1 == h->codecs[DS_FC]->store(h->codecs[DS_FC], map, "FC",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_FP]) {
+ if (-1 == h->codecs[DS_FP]->store(h->codecs[DS_FP], map, "FP",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_BS]) {
+ if (-1 == h->codecs[DS_BS]->store(h->codecs[DS_BS], map, "BS",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_IN]) {
+ if (-1 == h->codecs[DS_IN]->store(h->codecs[DS_IN], map, "IN",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_DL]) {
+ if (-1 == h->codecs[DS_DL]->store(h->codecs[DS_DL], map, "DL",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_BA]) {
+ if (-1 == h->codecs[DS_BA]->store(h->codecs[DS_BA], map, "BA",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_BB]) {
+ if (-1 == h->codecs[DS_BB]->store(h->codecs[DS_BB], map, "BB",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_MQ]) {
+ if (-1 == h->codecs[DS_MQ]->store(h->codecs[DS_MQ], map, "MQ",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_RN]) {
+ if (-1 == h->codecs[DS_RN]->store(h->codecs[DS_RN], map, "RN",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_QS]) {
+ if (-1 == h->codecs[DS_QS]->store(h->codecs[DS_QS], map, "QS",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_QQ]) {
+ if (-1 == h->codecs[DS_QQ]->store(h->codecs[DS_QQ], map, "QQ",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_RI]) {
+ if (-1 == h->codecs[DS_RI]->store(h->codecs[DS_RI], map, "RI",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (CRAM_MAJOR_VERS(fd->version) != 1) {
+ if (h->codecs[DS_SC]) {
+ if (-1 == h->codecs[DS_SC]->store(h->codecs[DS_SC], map, "SC",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_RS]) {
+ if (-1 == h->codecs[DS_RS]->store(h->codecs[DS_RS], map, "RS",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_PD]) {
+ if (-1 == h->codecs[DS_PD]->store(h->codecs[DS_PD], map, "PD",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_HC]) {
+ if (-1 == h->codecs[DS_HC]->store(h->codecs[DS_HC], map, "HC",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ }
+ if (h->codecs[DS_TM]) {
+ if (-1 == h->codecs[DS_TM]->store(h->codecs[DS_TM], map, "TM",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ if (h->codecs[DS_TV]) {
+ if (-1 == h->codecs[DS_TV]->store(h->codecs[DS_TV], map, "TV",
+ fd->version))
+ return NULL;
+ mc++;
+ }
+ itf8_put_blk(cb, BLOCK_SIZE(map) + itf8_size(mc));
+ itf8_put_blk(cb, mc);
+ BLOCK_APPEND(cb, BLOCK_DATA(map), BLOCK_SIZE(map));
+
+ /* tag encoding map */
+#if 0
+ mp = map; mc = 0;
+ if (h->tag_encoding_map) {
+ HashItem *hi;
+ HashIter *iter = HashTableIterCreate();
+ if (!iter)
+ return NULL;
+
+ while ((hi = HashTableIterNext(h->tag_encoding_map, iter))) {
+ cram_map *m = hi->data.p;
+ int sz;
+
+ mp += itf8_put(mp, (hi->key[0]<<16)|(hi->key[1]<<8)|hi->key[2]);
+ if (-1 == (sz = m->codec->store(m->codec, mp, NULL, fd->version)))
+ return NULL;
+ mp += sz;
+ mc++;
+ }
+
+ HashTableIterDestroy(iter);
+ }
+#else
+ mc = 0;
+ BLOCK_SIZE(map) = 0;
+ if (c->tags_used) {
+ khint_t k;
+
+#define TAG_ID(a) ((#a[0]<<8)+#a[1])
+
+ for (k = kh_begin(c->tags_used); k != kh_end(c->tags_used); k++) {
+ int key;
+ if (!kh_exist(c->tags_used, k))
+ continue;
+
+ mc++;
+ itf8_put_blk(map, kh_key(c->tags_used, k));
+
+ // use block content id 4
+ switch((key = kh_key(c->tags_used, k)) & 0xff) {
+ case 'Z': case 'H':
+ // string as byte_array_stop
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ BLOCK_APPEND(map,
+ "\005" // BYTE_ARRAY_STOP
+ "\005" // len
+ "\t" // stop-byte is also SAM separator
+ DS_aux_S "\000\000\000",
+ 7);
+ } else {
+ if (key>>8 == TAG_ID(OQ))
+ BLOCK_APPEND(map,
+ "\005" // BYTE_ARRAY_STOP
+ "\002" // len
+ "\t" // stop-byte is also SAM separator
+ DS_aux_OQ_S,
+ 4);
+ else if (key>>8 == TAG_ID(BQ))
+ BLOCK_APPEND(map,
+ "\005" // BYTE_ARRAY_STOP
+ "\002" // len
+ "\t" // stop-byte is also SAM separator
+ DS_aux_BQ_S,
+ 4);
+ else if (key>>8 == TAG_ID(BD))
+ BLOCK_APPEND(map,
+ "\005" // BYTE_ARRAY_STOP
+ "\002" // len
+ "\t" // stop-byte is also SAM separator
+ DS_aux_BD_S,
+ 4);
+ else if (key>>8 == TAG_ID(BI))
+ BLOCK_APPEND(map,
+ "\005" // BYTE_ARRAY_STOP
+ "\002" // len
+ "\t" // stop-byte is also SAM separator
+ DS_aux_BI_S,
+ 4);
+ else if ((key>>8 == TAG_ID(Q2)) ||
+ (key>>8 == TAG_ID(U2)) ||
+ (key>>8 == TAG_ID(QT)) ||
+ (key>>8 == TAG_ID(CQ)))
+ BLOCK_APPEND(map,
+ "\005" // BYTE_ARRAY_STOP
+ "\002" // len
+ "\t" // stop-byte is also SAM separator
+ DS_aux_oq_S,
+ 4);
+ else if ((key>>8 == TAG_ID(R2)) ||
+ (key>>8 == TAG_ID(E2)) ||
+ (key>>8 == TAG_ID(CS)) ||
+ (key>>8 == TAG_ID(BC)) ||
+ (key>>8 == TAG_ID(RT)))
+ BLOCK_APPEND(map,
+ "\005" // BYTE_ARRAY_STOP
+ "\002" // len
+ "\t" // stop-byte is also SAM separator
+ DS_aux_os_S,
+ 4);
+ else
+ BLOCK_APPEND(map,
+ "\005" // BYTE_ARRAY_STOP
+ "\002" // len
+ "\t" // stop-byte is also SAM separator
+ DS_aux_oz_S,
+ 4);
+ }
+ break;
+
+ case 'A': case 'c': case 'C':
+ // byte array len, 1 byte
+ BLOCK_APPEND(map,
+ "\004" // BYTE_ARRAY_LEN
+ "\011" // length
+ "\003" // HUFFMAN (len)
+ "\004" // huffman-len
+ "\001" // 1 symbol
+ "\001" // symbol=1 byte value
+ "\001" // 1 length
+ "\000" // length=0
+ "\001" // EXTERNAL (val)
+ "\001" // external-len
+ DS_aux_S,// content-id
+ 11);
+ break;
+
+ case 's': case 'S':
+ // byte array len, 2 byte
+ BLOCK_APPEND(map,
+ "\004" // BYTE_ARRAY_LEN
+ "\011" // length
+ "\003" // HUFFMAN (len)
+ "\004" // huffman-len
+ "\001" // 1 symbol
+ "\002" // symbol=2 byte value
+ "\001" // 1 length
+ "\000" // length=0
+ "\001" // EXTERNAL (val)
+ "\001" // external-len
+ DS_aux_S,// content-id
+ 11);
+ break;
+
+ case 'i': case 'I': case 'f':
+ // byte array len, 4 byte
+ BLOCK_APPEND(map,
+ "\004" // BYTE_ARRAY_LEN
+ "\011" // length
+ "\003" // HUFFMAN (len)
+ "\004" // huffman-len
+ "\001" // 1 symbol
+ "\004" // symbol=4 byte value
+ "\001" // 1 length
+ "\000" // length=0
+ "\001" // EXTERNAL (val)
+ "\001" // external-len
+ DS_aux_S,// content-id
+ 11);
+ break;
+
+ case 'B':
+ // Byte array of variable size, but we generate our tag
+ // byte stream at the wrong stage (during reading and not
+ // after slice header construction). So we use
+ // BYTE_ARRAY_LEN with the length codec being external
+ // too.
+ if ((key>>8 == TAG_ID(FZ)) || (key>>8 == TAG_ID(ZM)))
+ BLOCK_APPEND(map,
+ "\004" // BYTE_ARRAY_LEN
+ "\006" // length
+ "\001" // EXTERNAL (len)
+ "\001" // external-len
+ DS_aux_FZ_S // content-id
+ "\001" // EXTERNAL (val)
+ "\001" // external-len
+ DS_aux_FZ_S,// content-id
+ 8);
+ else
+ BLOCK_APPEND(map,
+ "\004" // BYTE_ARRAY_LEN
+ "\006" // length
+ "\001" // EXTERNAL (len)
+ "\001" // external-len
+ DS_aux_S // content-id
+ "\001" // EXTERNAL (val)
+ "\001" // external-len
+ DS_aux_S,// content-id
+ 8);
+ break;
+
+ default:
+ fprintf(stderr, "Unsupported SAM aux type '%c'\n",
+ kh_key(c->tags_used, k) & 0xff);
+ }
+ //mp += m->codec->store(m->codec, mp, NULL, fd->version);
+ }
+ }
+#endif
+ itf8_put_blk(cb, BLOCK_SIZE(map) + itf8_size(mc));
+ itf8_put_blk(cb, mc);
+ BLOCK_APPEND(cb, BLOCK_DATA(map), BLOCK_SIZE(map));
+
+ if (fd->verbose)
+ fprintf(stderr, "Wrote compression block header in %d bytes\n",
+ (int)BLOCK_SIZE(cb));
+
+ BLOCK_UPLEN(cb);
+
+ cram_free_block(map);
+
+ return cb;
+}
+
+
+/*
+ * Encodes a slice compression header.
+ *
+ * Returns cram_block on success
+ * NULL on failure
+ */
+cram_block *cram_encode_slice_header(cram_fd *fd, cram_slice *s) {
+ char *buf;
+ char *cp;
+ cram_block *b = cram_new_block(MAPPED_SLICE, 0);
+ int j;
+
+ if (!b)
+ return NULL;
+
+ if (NULL == (cp = buf = malloc(16+5*(8+s->hdr->num_blocks)))) {
+ cram_free_block(b);
+ return NULL;
+ }
+
+ cp += itf8_put(cp, s->hdr->ref_seq_id);
+ cp += itf8_put(cp, s->hdr->ref_seq_start);
+ cp += itf8_put(cp, s->hdr->ref_seq_span);
+ cp += itf8_put(cp, s->hdr->num_records);
+ if (CRAM_MAJOR_VERS(fd->version) == 2)
+ cp += itf8_put(cp, s->hdr->record_counter);
+ else if (CRAM_MAJOR_VERS(fd->version) >= 3)
+ cp += ltf8_put(cp, s->hdr->record_counter);
+ cp += itf8_put(cp, s->hdr->num_blocks);
+ cp += itf8_put(cp, s->hdr->num_content_ids);
+ for (j = 0; j < s->hdr->num_content_ids; j++) {
+ cp += itf8_put(cp, s->hdr->block_content_ids[j]);
+ }
+ if (s->hdr->content_type == MAPPED_SLICE)
+ cp += itf8_put(cp, s->hdr->ref_base_id);
+
+ if (CRAM_MAJOR_VERS(fd->version) != 1) {
+ memcpy(cp, s->hdr->md5, 16); cp += 16;
+ }
+
+ assert(cp-buf <= 16+5*(8+s->hdr->num_blocks));
+
+ b->data = (unsigned char *)buf;
+ b->comp_size = b->uncomp_size = cp-buf;
+
+ return b;
+}
+
+
+/*
+ * Encodes a single read.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+static int cram_encode_slice_read(cram_fd *fd,
+ cram_container *c,
+ cram_block_compression_hdr *h,
+ cram_slice *s,
+ cram_record *cr,
+ int *last_pos) {
+ int r = 0;
+ int32_t i32;
+ unsigned char uc;
+
+ //fprintf(stderr, "Encode seq %d, %d/%d FN=%d, %s\n", rec, core->byte, core->bit, cr->nfeature, s->name_ds->str + cr->name);
+
+ //printf("BF=0x%x\n", cr->flags);
+ // bf = cram_flag_swap[cr->flags];
+ i32 = fd->cram_flag_swap[cr->flags & 0xfff];
+ r |= h->codecs[DS_BF]->encode(s, h->codecs[DS_BF], (char *)&i32, 1);
+
+ i32 = cr->cram_flags & CRAM_FLAG_MASK;
+ r |= h->codecs[DS_CF]->encode(s, h->codecs[DS_CF], (char *)&i32, 1);
+
+ if (CRAM_MAJOR_VERS(fd->version) != 1 && s->hdr->ref_seq_id == -2)
+ r |= h->codecs[DS_RI]->encode(s, h->codecs[DS_RI], (char *)&cr->ref_id, 1);
+
+ r |= h->codecs[DS_RL]->encode(s, h->codecs[DS_RL], (char *)&cr->len, 1);
+
+ if (c->pos_sorted) {
+ i32 = cr->apos - *last_pos;
+ r |= h->codecs[DS_AP]->encode(s, h->codecs[DS_AP], (char *)&i32, 1);
+ *last_pos = cr->apos;
+ } else {
+ i32 = cr->apos;
+ r |= h->codecs[DS_AP]->encode(s, h->codecs[DS_AP], (char *)&i32, 1);
+ }
+
+ r |= h->codecs[DS_RG]->encode(s, h->codecs[DS_RG], (char *)&cr->rg, 1);
+
+ if (c->comp_hdr->read_names_included) {
+ // RN codec: Already stored in block[3].
+ }
+
+ if (cr->cram_flags & CRAM_FLAG_DETACHED) {
+ i32 = cr->mate_flags;
+ r |= h->codecs[DS_MF]->encode(s, h->codecs[DS_MF], (char *)&i32, 1);
+
+ if (!c->comp_hdr->read_names_included) {
+ // RN codec: Already stored in block[3].
+ }
+
+ r |= h->codecs[DS_NS]->encode(s, h->codecs[DS_NS],
+ (char *)&cr->mate_ref_id, 1);
+
+ r |= h->codecs[DS_NP]->encode(s, h->codecs[DS_NP],
+ (char *)&cr->mate_pos, 1);
+
+ r |= h->codecs[DS_TS]->encode(s, h->codecs[DS_TS],
+ (char *)&cr->tlen, 1);
+ } else if (cr->cram_flags & CRAM_FLAG_MATE_DOWNSTREAM) {
+ r |= h->codecs[DS_NF]->encode(s, h->codecs[DS_NF],
+ (char *)&cr->mate_line, 1);
+ }
+
+ /* Aux tags */
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ int j;
+ uc = cr->ntags;
+ r |= h->codecs[DS_TC]->encode(s, h->codecs[DS_TC], (char *)&uc, 1);
+
+ for (j = 0; j < cr->ntags; j++) {
+ uint32_t i32 = s->TN[cr->TN_idx + j]; // id
+ r |= h->codecs[DS_TN]->encode(s, h->codecs[DS_TN], (char *)&i32, 1);
+ }
+ } else {
+ r |= h->codecs[DS_TL]->encode(s, h->codecs[DS_TL], (char *)&cr->TL, 1);
+ }
+
+ // qual
+ // QS codec : Already stored in block[2].
+
+ // features (diffs)
+ if (!(cr->flags & BAM_FUNMAP)) {
+ int prev_pos = 0, j;
+
+ r |= h->codecs[DS_FN]->encode(s, h->codecs[DS_FN],
+ (char *)&cr->nfeature, 1);
+ for (j = 0; j < cr->nfeature; j++) {
+ cram_feature *f = &s->features[cr->feature + j];
+
+ uc = f->X.code;
+ r |= h->codecs[DS_FC]->encode(s, h->codecs[DS_FC], (char *)&uc, 1);
+ i32 = f->X.pos - prev_pos;
+ r |= h->codecs[DS_FP]->encode(s, h->codecs[DS_FP], (char *)&i32, 1);
+ prev_pos = f->X.pos;
+
+ switch(f->X.code) {
+ //char *seq;
+
+ case 'X':
+ //fprintf(stderr, " FC=%c FP=%d base=%d\n", f->X.code, i32, f->X.base);
+
+ uc = f->X.base;
+ r |= h->codecs[DS_BS]->encode(s, h->codecs[DS_BS],
+ (char *)&uc, 1);
+ break;
+ case 'S':
+ // Already done
+// r |= h->codecs[DS_SC]->encode(s, h->codecs[DS_SC],
+// BLOCK_DATA(s->soft_blk) + f->S.seq_idx,
+// f->S.len);
+
+// if (IS_CRAM_3_VERS(fd)) {
+// r |= h->codecs[DS_BB]->encode(s, h->codecs[DS_BB],
+// BLOCK_DATA(s->seqs_blk) + f->S.seq_idx,
+// f->S.len);
+// }
+ break;
+ case 'I':
+ //seq = DSTRING_STR(s->seqs_ds) + f->S.seq_idx;
+ //r |= h->codecs[DS_IN]->encode(s, h->codecs[DS_IN],
+ // seq, f->S.len);
+// if (IS_CRAM_3_VERS(fd)) {
+// r |= h->codecs[DS_BB]->encode(s, h->codecs[DS_BB],
+// BLOCK_DATA(s->seqs_blk) + f->I.seq_idx,
+// f->I.len);
+// }
+ break;
+ case 'i':
+ uc = f->i.base;
+ r |= h->codecs[DS_BA]->encode(s, h->codecs[DS_BA],
+ (char *)&uc, 1);
+ //seq = DSTRING_STR(s->seqs_ds) + f->S.seq_idx;
+ //r |= h->codecs[DS_IN]->encode(s, h->codecs[DS_IN],
+ // seq, 1);
+ break;
+ case 'D':
+ i32 = f->D.len;
+ r |= h->codecs[DS_DL]->encode(s, h->codecs[DS_DL],
+ (char *)&i32, 1);
+ break;
+
+ case 'B':
+ // // Used when we try to store a non ACGTN base or an N
+ // // that aligns against a non ACGTN reference
+
+ uc = f->B.base;
+ r |= h->codecs[DS_BA]->encode(s, h->codecs[DS_BA],
+ (char *)&uc, 1);
+
+ // Already added
+ // uc = f->B.qual;
+ // r |= h->codecs[DS_QS]->encode(s, h->codecs[DS_QS],
+ // (char *)&uc, 1);
+ break;
+
+ case 'b':
+ // string of bases
+ r |= h->codecs[DS_BB]->encode(s, h->codecs[DS_BB],
+ (char *)BLOCK_DATA(s->seqs_blk)
+ + f->b.seq_idx,
+ f->b.len);
+ break;
+
+ case 'Q':
+ // Already added
+ // uc = f->B.qual;
+ // r |= h->codecs[DS_QS]->encode(s, h->codecs[DS_QS],
+ // (char *)&uc, 1);
+ break;
+
+ case 'N':
+ i32 = f->N.len;
+ r |= h->codecs[DS_RS]->encode(s, h->codecs[DS_RS],
+ (char *)&i32, 1);
+ break;
+
+ case 'P':
+ i32 = f->P.len;
+ r |= h->codecs[DS_PD]->encode(s, h->codecs[DS_PD],
+ (char *)&i32, 1);
+ break;
+
+ case 'H':
+ i32 = f->H.len;
+ r |= h->codecs[DS_HC]->encode(s, h->codecs[DS_HC],
+ (char *)&i32, 1);
+ break;
+
+
+ default:
+ fprintf(stderr, "unhandled feature code %c\n",
+ f->X.code);
+ return -1;
+ }
+ }
+
+ r |= h->codecs[DS_MQ]->encode(s, h->codecs[DS_MQ],
+ (char *)&cr->mqual, 1);
+ } else {
+ char *seq = (char *)BLOCK_DATA(s->seqs_blk) + cr->seq;
+ if (cr->len)
+ r |= h->codecs[DS_BA]->encode(s, h->codecs[DS_BA], seq, cr->len);
+ }
+
+ return r ? -1 : 0;
+}
+
+
+/*
+ * Applies various compression methods to specific blocks, depending on
+ * known observations of how data series compress.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+static int cram_compress_slice(cram_fd *fd, cram_slice *s) {
+ int level = fd->level, i;
+ int method = 1<<GZIP | 1<<GZIP_RLE, methodF = method;
+
+ /* Compress the CORE Block too, with minimal zlib level */
+ if (level > 5 && s->block[0]->uncomp_size > 500)
+ cram_compress_block(fd, s->block[0], NULL, GZIP, 1);
+
+ if (fd->use_bz2)
+ method |= 1<<BZIP2;
+
+ if (fd->use_rans)
+ method |= (1<<RANS0) | (1<<RANS1);
+
+ if (fd->use_lzma)
+ method |= (1<<LZMA);
+
+ /* Faster method for data series we only need entropy encoding on */
+ methodF = method & ~(1<<GZIP | 1<<BZIP2 | 1<<LZMA);
+ if (level >= 6)
+ methodF = method;
+
+
+ /* Specific compression methods for certain block types */
+ if (cram_compress_block(fd, s->block[DS_IN], fd->m[DS_IN], //IN (seq)
+ method, level))
+ return -1;
+
+ if (fd->level == 0) {
+ /* Do nothing */
+ } else if (fd->level == 1) {
+ if (cram_compress_block(fd, s->block[DS_QS], fd->m[DS_QS],
+ methodF, 1))
+ return -1;
+ for (i = DS_aux; i <= DS_aux_oz; i++) {
+ if (s->block[i])
+ if (cram_compress_block(fd, s->block[i], fd->m[i],
+ method, 1))
+ return -1;
+ }
+ } else if (fd->level < 3) {
+ if (cram_compress_block(fd, s->block[DS_QS], fd->m[DS_QS],
+ method, 1))
+ return -1;
+ if (cram_compress_block(fd, s->block[DS_BA], fd->m[DS_BA],
+ method, 1))
+ return -1;
+ if (s->block[DS_BB])
+ if (cram_compress_block(fd, s->block[DS_BB], fd->m[DS_BB],
+ method, 1))
+ return -1;
+ for (i = DS_aux; i <= DS_aux_oz; i++) {
+ if (s->block[i])
+ if (cram_compress_block(fd, s->block[i], fd->m[i],
+ method, level))
+ return -1;
+ }
+ } else {
+ if (cram_compress_block(fd, s->block[DS_QS], fd->m[DS_QS],
+ method, level))
+ return -1;
+ if (cram_compress_block(fd, s->block[DS_BA], fd->m[DS_BA],
+ method, level))
+ return -1;
+ if (s->block[DS_BB])
+ if (cram_compress_block(fd, s->block[DS_BB], fd->m[DS_BB],
+ method, level))
+ return -1;
+ for (i = DS_aux; i <= DS_aux_oz; i++) {
+ if (s->block[i])
+ if (cram_compress_block(fd, s->block[i], fd->m[i],
+ method, level))
+ return -1;
+ }
+ }
+
+ // NAME: best is generally xz, bzip2, zlib then rans1
+ // It benefits well from a little bit extra compression level.
+ if (cram_compress_block(fd, s->block[DS_RN], fd->m[DS_RN],
+ method & ~(1<<RANS0 | 1<<GZIP_RLE),
+ MIN(9,level)))
+ return -1;
+
+ // NS shows strong local correlation as rearrangements are localised
+ if (s->block[DS_NS] != s->block[0])
+ if (cram_compress_block(fd, s->block[DS_NS], fd->m[DS_NS],
+ method, level))
+ return -1;
+
+
+ /*
+ * Minimal compression of any block still uncompressed, bar CORE
+ */
+ {
+ int i;
+ for (i = 1; i < DS_END; i++) {
+ if (!s->block[i] || s->block[i] == s->block[0])
+ continue;
+
+ // fast methods only
+ if (s->block[i]->method == RAW) {
+ cram_compress_block(fd, s->block[i], fd->m[i],
+ methodF, level);
+ }
+ }
+ }
+
+ return 0;
+}
+
+/*
+ * Encodes a single slice from a container
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+static int cram_encode_slice(cram_fd *fd, cram_container *c,
+ cram_block_compression_hdr *h, cram_slice *s) {
+ int rec, r = 0, last_pos;
+ int embed_ref;
+ enum cram_DS_ID id;
+
+ embed_ref = fd->embed_ref && s->hdr->ref_seq_id != -1 ? 1 : 0;
+
+ /*
+ * Slice external blocks:
+ * ID 0 => base calls (insertions, soft-clip)
+ * ID 1 => qualities
+ * ID 2 => names
+ * ID 3 => TS (insert size), NP (next frag)
+ * ID 4 => tag values
+ * ID 6 => tag IDs (TN), if CRAM_V1.0
+ * ID 7 => TD tag dictionary, if !CRAM_V1.0
+ */
+
+ /* Create cram slice header */
+ s->hdr->ref_base_id = embed_ref ? DS_ref : -1;
+ s->hdr->record_counter = c->num_records + c->record_counter;
+ c->num_records += s->hdr->num_records;
+
+ s->block = calloc(DS_END, sizeof(s->block[0]));
+ s->hdr->block_content_ids = malloc(DS_END * sizeof(int32_t));
+ if (!s->block || !s->hdr->block_content_ids)
+ return -1;
+
+ // Create first fixed blocks, always external.
+ // CORE
+ if (!(s->block[0] = cram_new_block(CORE, 0)))
+ return -1;
+
+ // TN block for CRAM v1
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ if (h->codecs[DS_TN]->codec == E_EXTERNAL) {
+ if (!(s->block[DS_TN] = cram_new_block(EXTERNAL,DS_TN))) return -1;
+ h->codecs[DS_TN]->external.content_id = DS_TN;
+ } else {
+ s->block[DS_TN] = s->block[0];
+ }
+ s->block[DS_TN] = s->block[DS_TN];
+ }
+
+ // Embedded reference
+ if (embed_ref) {
+ if (!(s->block[DS_ref] = cram_new_block(EXTERNAL, DS_ref)))
+ return -1;
+ s->ref_id = DS_ref; // needed?
+ BLOCK_APPEND(s->block[DS_ref],
+ c->ref + c->first_base - c->ref_start,
+ c->last_base - c->first_base + 1);
+ }
+
+ /*
+ * All the data-series blocks if appropriate.
+ */
+ for (id = DS_BF; id < DS_TN; id++) {
+ if (h->codecs[id] && (h->codecs[id]->codec == E_EXTERNAL ||
+ h->codecs[id]->codec == E_BYTE_ARRAY_STOP ||
+ h->codecs[id]->codec == E_BYTE_ARRAY_LEN)) {
+ switch (h->codecs[id]->codec) {
+ case E_EXTERNAL:
+ if (!(s->block[id] = cram_new_block(EXTERNAL, id)))
+ return -1;
+ h->codecs[id]->external.content_id = id;
+ break;
+
+ case E_BYTE_ARRAY_STOP:
+ if (!(s->block[id] = cram_new_block(EXTERNAL, id)))
+ return -1;
+ h->codecs[id]->byte_array_stop.content_id = id;
+ break;
+
+ case E_BYTE_ARRAY_LEN: {
+ cram_codec *cc;
+
+ cc = h->codecs[id]->e_byte_array_len.len_codec;
+ if (cc->codec == E_EXTERNAL) {
+ int eid = cc->external.content_id;
+ if (!(s->block[eid] = cram_new_block(EXTERNAL, eid)))
+ return -1;
+ cc->external.content_id = eid;
+ cc->out = s->block[eid];
+ }
+
+ cc = h->codecs[id]->e_byte_array_len.val_codec;
+ if (cc->codec == E_EXTERNAL) {
+ int eid = cc->external.content_id;
+ if (!s->block[eid])
+ if (!(s->block[eid] = cram_new_block(EXTERNAL, eid)))
+ return -1;
+ cc->external.content_id = eid;
+ cc->out = s->block[eid];
+ }
+ break;
+ }
+ default:
+ break;
+ }
+ } else {
+ if (!(id == DS_BB && !h->codecs[DS_BB]))
+ s->block[id] = s->block[0];
+ }
+ if (h->codecs[id])
+ h->codecs[id]->out = s->block[id];
+ }
+
+ /* Encode reads */
+ last_pos = s->hdr->ref_seq_start;
+ for (rec = 0; rec < s->hdr->num_records; rec++) {
+ cram_record *cr = &s->crecs[rec];
+ if (cram_encode_slice_read(fd, c, h, s, cr, &last_pos) == -1)
+ return -1;
+ }
+
+ s->block[0]->uncomp_size = s->block[0]->byte + (s->block[0]->bit < 7);
+ s->block[0]->comp_size = s->block[0]->uncomp_size;
+
+ // Make sure the fixed blocks point to the correct sources
+ s->block[DS_IN] = s->base_blk; s->base_blk = NULL;
+ s->block[DS_QS] = s->qual_blk; s->qual_blk = NULL;
+ s->block[DS_RN] = s->name_blk; s->name_blk = NULL;
+ s->block[DS_SC] = s->soft_blk; s->soft_blk = NULL;
+ s->block[DS_aux]= s->aux_blk; s->aux_blk = NULL;
+ s->block[DS_aux_OQ]= s->aux_OQ_blk; s->aux_OQ_blk = NULL;
+ s->block[DS_aux_BQ]= s->aux_BQ_blk; s->aux_BQ_blk = NULL;
+ s->block[DS_aux_BD]= s->aux_BD_blk; s->aux_BD_blk = NULL;
+ s->block[DS_aux_BI]= s->aux_BI_blk; s->aux_BI_blk = NULL;
+ s->block[DS_aux_FZ]= s->aux_FZ_blk; s->aux_FZ_blk = NULL;
+ s->block[DS_aux_oq]= s->aux_oq_blk; s->aux_oq_blk = NULL;
+ s->block[DS_aux_os]= s->aux_os_blk; s->aux_os_blk = NULL;
+ s->block[DS_aux_oz]= s->aux_oz_blk; s->aux_oz_blk = NULL;
+
+ // Ensure block sizes are up to date.
+ for (id = 1; id < DS_END; id++) {
+ if (!s->block[id] || s->block[id] == s->block[0])
+ continue;
+
+ if (s->block[id]->uncomp_size == 0)
+ BLOCK_UPLEN(s->block[id]);
+ }
+
+ // Compress it all
+ if (cram_compress_slice(fd, s) == -1)
+ return -1;
+
+ // Collapse empty blocks and create hdr_block
+ {
+ int i, j;
+ for (i = j = 1; i < DS_END; i++) {
+ if (!s->block[i] || s->block[i] == s->block[0])
+ continue;
+ if (s->block[i]->uncomp_size == 0) {
+ cram_free_block(s->block[i]);
+ s->block[i] = NULL;
+ continue;
+ }
+ s->block[j] = s->block[i];
+ s->hdr->block_content_ids[j-1] = s->block[i]->content_id;
+ j++;
+ }
+ s->hdr->num_content_ids = j-1;
+ s->hdr->num_blocks = j;
+
+ if (!(s->hdr_block = cram_encode_slice_header(fd, s)))
+ return -1;
+ }
+
+ return r ? -1 : 0;
+}
+
+/*
+ * Encodes all slices in a container into blocks.
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_encode_container(cram_fd *fd, cram_container *c) {
+ int i, j, slice_offset;
+ cram_block_compression_hdr *h = c->comp_hdr;
+ cram_block *c_hdr;
+ int multi_ref = 0;
+ int r1, r2, sn, nref;
+ spare_bams *spares;
+
+ /* Cache references up-front if we have unsorted access patterns */
+ pthread_mutex_lock(&fd->ref_lock);
+ nref = fd->refs->nref;
+ pthread_mutex_unlock(&fd->ref_lock);
+
+ if (!fd->no_ref && c->refs_used) {
+ for (i = 0; i < nref; i++) {
+ if (c->refs_used[i])
+ cram_get_ref(fd, i, 1, 0);
+ }
+ }
+
+ /* To create M5 strings */
+ /* Fetch reference sequence */
+ if (!fd->no_ref) {
+ bam_seq_t *b = c->bams[0];
+ char *ref;
+
+ ref = cram_get_ref(fd, bam_ref(b), 1, 0);
+ if (!ref && bam_ref(b) >= 0) {
+ fprintf(stderr, "Failed to load reference #%d\n", bam_ref(b));
+ return -1;
+ }
+ if ((c->ref_id = bam_ref(b)) >= 0) {
+ c->ref_seq_id = c->ref_id;
+ c->ref = fd->refs->ref_id[c->ref_seq_id]->seq;
+ c->ref_start = 1;
+ c->ref_end = fd->refs->ref_id[c->ref_seq_id]->length;
+ } else {
+ c->ref_seq_id = c->ref_id; // FIXME remove one var!
+ }
+ } else {
+ c->ref_id = bam_ref(c->bams[0]);
+ cram_ref_incr(fd->refs, c->ref_id);
+ c->ref_seq_id = c->ref_id;
+ }
+
+ /* Turn bams into cram_records and gather basic stats */
+ for (r1 = sn = 0; r1 < c->curr_c_rec; sn++) {
+ cram_slice *s = c->slices[sn];
+ int first_base = INT_MAX, last_base = INT_MIN;
+
+ assert(sn < c->curr_slice);
+
+ /* FIXME: we could create our slice objects here too instead of
+ * in cram_put_bam_seq. It's more natural here and also this is
+ * bit is threaded so it's less work in the main thread.
+ */
+
+ for (r2 = 0; r1 < c->curr_c_rec && r2 < c->max_rec; r1++, r2++) {
+ cram_record *cr = &s->crecs[r2];
+ bam_seq_t *b = c->bams[r1];
+
+ /* If multi-ref we need to cope with changing reference per seq */
+ if (c->multi_seq && !fd->no_ref) {
+ if (bam_ref(b) != c->ref_seq_id && bam_ref(b) >= 0) {
+ if (c->ref_seq_id >= 0)
+ cram_ref_decr(fd->refs, c->ref_seq_id);
+
+ if (!cram_get_ref(fd, bam_ref(b), 1, 0)) {
+ fprintf(stderr, "Failed to load reference #%d\n",
+ bam_ref(b));
+ return -1;
+ }
+
+ c->ref_seq_id = bam_ref(b); // overwritten later by -2
+ assert(fd->refs->ref_id[c->ref_seq_id]->seq);
+ c->ref = fd->refs->ref_id[c->ref_seq_id]->seq;
+ c->ref_start = 1;
+ c->ref_end = fd->refs->ref_id[c->ref_seq_id]->length;
+ }
+ }
+
+ if (process_one_read(fd, c, s, cr, b, r2) != 0)
+ return -1;
+
+ if (first_base > cr->apos)
+ first_base = cr->apos;
+
+ if (last_base < cr->aend)
+ last_base = cr->aend;
+ }
+
+ if (c->multi_seq) {
+ s->hdr->ref_seq_id = -2;
+ s->hdr->ref_seq_start = 0;
+ s->hdr->ref_seq_span = 0;
+ } else {
+ s->hdr->ref_seq_id = c->ref_id;
+ s->hdr->ref_seq_start = first_base;
+ s->hdr->ref_seq_span = last_base - first_base + 1;
+ }
+ s->hdr->num_records = r2;
+ }
+
+ if (c->multi_seq && !fd->no_ref) {
+ if (c->ref_seq_id >= 0)
+ cram_ref_decr(fd->refs, c->ref_seq_id);
+ }
+
+ /* Link our bams[] array onto the spare bam list for reuse */
+ spares = malloc(sizeof(*spares));
+ pthread_mutex_lock(&fd->bam_list_lock);
+ spares->bams = c->bams;
+ spares->next = fd->bl;
+ fd->bl = spares;
+ pthread_mutex_unlock(&fd->bam_list_lock);
+ c->bams = NULL;
+
+ /* Detect if a multi-seq container */
+ cram_stats_encoding(fd, c->stats[DS_RI]);
+ multi_ref = c->stats[DS_RI]->nvals > 1;
+
+ if (multi_ref) {
+ if (fd->verbose)
+ fprintf(stderr, "Multi-ref container\n");
+ c->ref_seq_id = -2;
+ c->ref_seq_start = 0;
+ c->ref_seq_span = 0;
+ }
+
+
+ /* Compute MD5s */
+ for (i = 0; i < c->curr_slice; i++) {
+ cram_slice *s = c->slices[i];
+
+ if (CRAM_MAJOR_VERS(fd->version) != 1) {
+ if (s->hdr->ref_seq_id >= 0 && c->multi_seq == 0 && !fd->no_ref) {
+ hts_md5_context *md5 = hts_md5_init();
+ if (!md5)
+ return -1;
+ hts_md5_update(md5,
+ c->ref + s->hdr->ref_seq_start - c->ref_start,
+ s->hdr->ref_seq_span);
+ hts_md5_final(s->hdr->md5, md5);
+ hts_md5_destroy(md5);
+ } else {
+ memset(s->hdr->md5, 0, 16);
+ }
+ }
+ }
+
+ c->num_records = 0;
+ c->num_blocks = 1; // cram_block_compression_hdr
+ c->length = 0;
+
+ //fprintf(stderr, "=== BF ===\n");
+ h->codecs[DS_BF] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_BF]),
+ c->stats[DS_BF], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== CF ===\n");
+ h->codecs[DS_CF] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_CF]),
+ c->stats[DS_CF], E_INT, NULL,
+ fd->version);
+// fprintf(stderr, "=== RN ===\n");
+// h->codecs[DS_RN] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_RN]),
+// c->stats[DS_RN], E_BYTE_ARRAY, NULL,
+// fd->version);
+
+ //fprintf(stderr, "=== AP ===\n");
+ if (c->pos_sorted) {
+ h->codecs[DS_AP] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_AP]),
+ c->stats[DS_AP], E_INT, NULL,
+ fd->version);
+ } else {
+ int p[2] = {0, c->max_apos};
+ h->codecs[DS_AP] = cram_encoder_init(E_BETA, NULL, E_INT, p,
+ fd->version);
+ }
+
+ //fprintf(stderr, "=== RG ===\n");
+ h->codecs[DS_RG] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_RG]),
+ c->stats[DS_RG], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== MQ ===\n");
+ h->codecs[DS_MQ] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_MQ]),
+ c->stats[DS_MQ], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== NS ===\n");
+ h->codecs[DS_NS] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_NS]),
+ c->stats[DS_NS], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== MF ===\n");
+ h->codecs[DS_MF] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_MF]),
+ c->stats[DS_MF], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== TS ===\n");
+ h->codecs[DS_TS] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_TS]),
+ c->stats[DS_TS], E_INT, NULL,
+ fd->version);
+ //fprintf(stderr, "=== NP ===\n");
+ h->codecs[DS_NP] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_NP]),
+ c->stats[DS_NP], E_INT, NULL,
+ fd->version);
+ //fprintf(stderr, "=== NF ===\n");
+ h->codecs[DS_NF] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_NF]),
+ c->stats[DS_NF], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== RL ===\n");
+ h->codecs[DS_RL] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_RL]),
+ c->stats[DS_RL], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== FN ===\n");
+ h->codecs[DS_FN] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_FN]),
+ c->stats[DS_FN], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== FC ===\n");
+ h->codecs[DS_FC] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_FC]),
+ c->stats[DS_FC], E_BYTE, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== FP ===\n");
+ h->codecs[DS_FP] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_FP]),
+ c->stats[DS_FP], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== DL ===\n");
+ h->codecs[DS_DL] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_DL]),
+ c->stats[DS_DL], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== BA ===\n");
+ h->codecs[DS_BA] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_BA]),
+ c->stats[DS_BA], E_BYTE, NULL,
+ fd->version);
+
+ if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ cram_byte_array_len_encoder e;
+
+ e.len_encoding = E_EXTERNAL;
+ e.len_dat = (void *)DS_BB_len;
+ //e.len_dat = (void *)DS_BB;
+
+ e.val_encoding = E_EXTERNAL;
+ e.val_dat = (void *)DS_BB;
+
+ h->codecs[DS_BB] = cram_encoder_init(E_BYTE_ARRAY_LEN, NULL,
+ E_BYTE_ARRAY, (void *)&e,
+ fd->version);
+ } else {
+ h->codecs[DS_BB] = NULL;
+ }
+
+ //fprintf(stderr, "=== BS ===\n");
+ h->codecs[DS_BS] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_BS]),
+ c->stats[DS_BS], E_BYTE, NULL,
+ fd->version);
+
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ h->codecs[DS_TL] = NULL;
+ h->codecs[DS_RI] = NULL;
+ h->codecs[DS_RS] = NULL;
+ h->codecs[DS_PD] = NULL;
+ h->codecs[DS_HC] = NULL;
+ h->codecs[DS_SC] = NULL;
+
+ //fprintf(stderr, "=== TC ===\n");
+ h->codecs[DS_TC] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_TC]),
+ c->stats[DS_TC], E_BYTE, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== TN ===\n");
+ h->codecs[DS_TN] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_TN]),
+ c->stats[DS_TN], E_INT, NULL,
+ fd->version);
+ } else {
+ h->codecs[DS_TC] = NULL;
+ h->codecs[DS_TN] = NULL;
+
+ //fprintf(stderr, "=== TL ===\n");
+ h->codecs[DS_TL] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_TL]),
+ c->stats[DS_TL], E_INT, NULL,
+ fd->version);
+
+
+ //fprintf(stderr, "=== RI ===\n");
+ h->codecs[DS_RI] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_RI]),
+ c->stats[DS_RI], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== RS ===\n");
+ h->codecs[DS_RS] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_RS]),
+ c->stats[DS_RS], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== PD ===\n");
+ h->codecs[DS_PD] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_PD]),
+ c->stats[DS_PD], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== HC ===\n");
+ h->codecs[DS_HC] = cram_encoder_init(cram_stats_encoding(fd, c->stats[DS_HC]),
+ c->stats[DS_HC], E_INT, NULL,
+ fd->version);
+
+ //fprintf(stderr, "=== SC ===\n");
+ if (1) {
+ int i2[2] = {0, DS_SC};
+
+ h->codecs[DS_SC] = cram_encoder_init(E_BYTE_ARRAY_STOP, NULL,
+ E_BYTE_ARRAY, (void *)i2,
+ fd->version);
+ } else {
+ // Appears to be no practical benefit to using this method,
+ // but it may work better if we start mixing SC, IN and BB
+ // elements into the same external block.
+ cram_byte_array_len_encoder e;
+
+ e.len_encoding = E_EXTERNAL;
+ e.len_dat = (void *)DS_SC_len;
+
+ e.val_encoding = E_EXTERNAL;
+ e.val_dat = (void *)DS_SC;
+
+ h->codecs[DS_SC] = cram_encoder_init(E_BYTE_ARRAY_LEN, NULL,
+ E_BYTE_ARRAY, (void *)&e,
+ fd->version);
+ }
+ }
+
+ //fprintf(stderr, "=== IN ===\n");
+ {
+ int i2[2] = {0, DS_IN};
+ h->codecs[DS_IN] = cram_encoder_init(E_BYTE_ARRAY_STOP, NULL,
+ E_BYTE_ARRAY, (void *)i2,
+ fd->version);
+ }
+
+ h->codecs[DS_QS] = cram_encoder_init(E_EXTERNAL, NULL, E_BYTE,
+ (void *)DS_QS,
+ fd->version);
+ {
+ int i2[2] = {0, DS_RN};
+ h->codecs[DS_RN] = cram_encoder_init(E_BYTE_ARRAY_STOP, NULL,
+ E_BYTE_ARRAY, (void *)i2,
+ fd->version);
+ }
+
+
+ /* Encode slices */
+ for (i = 0; i < c->curr_slice; i++) {
+ if (fd->verbose)
+ fprintf(stderr, "Encode slice %d\n", i);
+ if (cram_encode_slice(fd, c, h, c->slices[i]) != 0)
+ return -1;
+ }
+
+ /* Create compression header */
+ {
+ h->ref_seq_id = c->ref_seq_id;
+ h->ref_seq_start = c->ref_seq_start;
+ h->ref_seq_span = c->ref_seq_span;
+ h->num_records = c->num_records;
+
+ h->mapped_qs_included = 0; // fixme
+ h->unmapped_qs_included = 0; // fixme
+ h->AP_delta = c->pos_sorted;
+ // h->... fixme
+ memcpy(h->substitution_matrix, CRAM_SUBST_MATRIX, 20);
+
+ if (!(c_hdr = cram_encode_compression_header(fd, c, h)))
+ return -1;
+ }
+
+ /* Compute landmarks */
+ /* Fill out slice landmarks */
+ c->num_landmarks = c->curr_slice;
+ c->landmark = malloc(c->num_landmarks * sizeof(*c->landmark));
+ if (!c->landmark)
+ return -1;
+
+ /*
+ * Slice offset starts after the first block, so we need to simulate
+ * writing it to work out the correct offset
+ */
+ {
+ slice_offset = c_hdr->method == RAW
+ ? c_hdr->uncomp_size
+ : c_hdr->comp_size;
+ slice_offset += 2 + 4*(CRAM_MAJOR_VERS(fd->version) >= 3) +
+ itf8_size(c_hdr->content_id) +
+ itf8_size(c_hdr->comp_size) +
+ itf8_size(c_hdr->uncomp_size);
+ }
+
+ c->ref_seq_id = c->slices[0]->hdr->ref_seq_id;
+ c->ref_seq_start = c->slices[0]->hdr->ref_seq_start;
+ c->ref_seq_span = c->slices[0]->hdr->ref_seq_span;
+ for (i = 0; i < c->curr_slice; i++) {
+ cram_slice *s = c->slices[i];
+
+ c->num_blocks += s->hdr->num_blocks + 1; // slice header
+ c->landmark[i] = slice_offset;
+
+ if (s->hdr->ref_seq_start + s->hdr->ref_seq_span >
+ c->ref_seq_start + c->ref_seq_span) {
+ c->ref_seq_span = s->hdr->ref_seq_start + s->hdr->ref_seq_span
+ - c->ref_seq_start;
+ }
+
+ slice_offset += s->hdr_block->method == RAW
+ ? s->hdr_block->uncomp_size
+ : s->hdr_block->comp_size;
+
+ slice_offset += 2 + 4*(CRAM_MAJOR_VERS(fd->version) >= 3) +
+ itf8_size(s->hdr_block->content_id) +
+ itf8_size(s->hdr_block->comp_size) +
+ itf8_size(s->hdr_block->uncomp_size);
+
+ for (j = 0; j < s->hdr->num_blocks; j++) {
+ slice_offset += 2 + 4*(CRAM_MAJOR_VERS(fd->version) >= 3) +
+ itf8_size(s->block[j]->content_id) +
+ itf8_size(s->block[j]->comp_size) +
+ itf8_size(s->block[j]->uncomp_size);
+
+ slice_offset += s->block[j]->method == RAW
+ ? s->block[j]->uncomp_size
+ : s->block[j]->comp_size;
+ }
+ }
+ c->length += slice_offset; // just past the final slice
+
+ c->comp_hdr_block = c_hdr;
+
+ if (c->ref_seq_id >= 0) {
+ cram_ref_decr(fd->refs, c->ref_seq_id);
+ }
+
+ /* Cache references up-front if we have unsorted access patterns */
+ if (!fd->no_ref && c->refs_used) {
+ for (i = 0; i < fd->refs->nref; i++) {
+ if (c->refs_used[i])
+ cram_ref_decr(fd->refs, i);
+ }
+ }
+
+ return 0;
+}
+
+
+/*
+ * Adds a feature code to a read within a slice. For purposes of minimising
+ * memory allocations and fragmentation we have one array of features for all
+ * reads within the slice. We return the index into this array for this new
+ * feature.
+ *
+ * Returns feature index on success
+ * -1 on failure.
+ */
+static int cram_add_feature(cram_container *c, cram_slice *s,
+ cram_record *r, cram_feature *f) {
+ if (s->nfeatures >= s->afeatures) {
+ s->afeatures = s->afeatures ? s->afeatures*2 : 1024;
+ s->features = realloc(s->features, s->afeatures*sizeof(*s->features));
+ if (!s->features)
+ return -1;
+ }
+
+ if (!r->nfeature++) {
+ r->feature = s->nfeatures;
+ cram_stats_add(c->stats[DS_FP], f->X.pos);
+ } else {
+ cram_stats_add(c->stats[DS_FP],
+ f->X.pos - s->features[r->feature + r->nfeature-2].X.pos);
+ }
+ cram_stats_add(c->stats[DS_FC], f->X.code);
+
+ s->features[s->nfeatures++] = *f;
+
+ return 0;
+}
+
+static int cram_add_substitution(cram_fd *fd, cram_container *c,
+ cram_slice *s, cram_record *r,
+ int pos, char base, char qual, char ref) {
+ cram_feature f;
+
+ // seq=ACGTN vs ref=ACGT or seq=ACGT vs ref=ACGTN
+ if (fd->L2[(uc)base]<4 || (fd->L2[(uc)base]<5 && fd->L2[(uc)ref]<4)) {
+ f.X.pos = pos+1;
+ f.X.code = 'X';
+ f.X.base = fd->cram_sub_matrix[ref&0x1f][base&0x1f];
+ cram_stats_add(c->stats[DS_BS], f.X.base);
+ } else {
+ f.B.pos = pos+1;
+ f.B.code = 'B';
+ f.B.base = base;
+ f.B.qual = qual;
+ cram_stats_add(c->stats[DS_BA], f.B.base);
+ cram_stats_add(c->stats[DS_QS], f.B.qual);
+ BLOCK_APPEND_CHAR(s->qual_blk, qual);
+ }
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_bases(cram_fd *fd, cram_container *c,
+ cram_slice *s, cram_record *r,
+ int pos, int len, char *base) {
+ cram_feature f;
+
+ f.b.pos = pos+1;
+ f.b.code = 'b';
+ f.b.seq_idx = base - (char *)BLOCK_DATA(s->seqs_blk);
+ f.b.len = len;
+
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_base(cram_fd *fd, cram_container *c,
+ cram_slice *s, cram_record *r,
+ int pos, char base, char qual) {
+ cram_feature f;
+ f.B.pos = pos+1;
+ f.B.code = 'B';
+ f.B.base = base;
+ f.B.qual = qual;
+ cram_stats_add(c->stats[DS_BA], base);
+ cram_stats_add(c->stats[DS_QS], qual);
+ BLOCK_APPEND_CHAR(s->qual_blk, qual);
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_quality(cram_fd *fd, cram_container *c,
+ cram_slice *s, cram_record *r,
+ int pos, char qual) {
+ cram_feature f;
+ f.Q.pos = pos+1;
+ f.Q.code = 'Q';
+ f.Q.qual = qual;
+ cram_stats_add(c->stats[DS_QS], qual);
+ BLOCK_APPEND_CHAR(s->qual_blk, qual);
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_deletion(cram_container *c, cram_slice *s, cram_record *r,
+ int pos, int len, char *base) {
+ cram_feature f;
+ f.D.pos = pos+1;
+ f.D.code = 'D';
+ f.D.len = len;
+ cram_stats_add(c->stats[DS_DL], len);
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_softclip(cram_container *c, cram_slice *s, cram_record *r,
+ int pos, int len, char *base, int version) {
+ cram_feature f;
+ f.S.pos = pos+1;
+ f.S.code = 'S';
+ f.S.len = len;
+ switch (CRAM_MAJOR_VERS(version)) {
+ case 1:
+ f.S.seq_idx = BLOCK_SIZE(s->base_blk);
+ BLOCK_APPEND(s->base_blk, base, len);
+ BLOCK_APPEND_CHAR(s->base_blk, '\0');
+ break;
+
+ case 2:
+ default:
+ f.S.seq_idx = BLOCK_SIZE(s->soft_blk);
+ if (base) {
+ BLOCK_APPEND(s->soft_blk, base, len);
+ } else {
+ int i;
+ for (i = 0; i < len; i++)
+ BLOCK_APPEND_CHAR(s->soft_blk, 'N');
+ }
+ BLOCK_APPEND_CHAR(s->soft_blk, '\0');
+ break;
+
+// default:
+// // v3.0 onwards uses BB data-series
+// f.S.seq_idx = BLOCK_SIZE(s->soft_blk);
+ }
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_hardclip(cram_container *c, cram_slice *s, cram_record *r,
+ int pos, int len, char *base) {
+ cram_feature f;
+ f.S.pos = pos+1;
+ f.S.code = 'H';
+ f.S.len = len;
+ cram_stats_add(c->stats[DS_HC], len);
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_skip(cram_container *c, cram_slice *s, cram_record *r,
+ int pos, int len, char *base) {
+ cram_feature f;
+ f.S.pos = pos+1;
+ f.S.code = 'N';
+ f.S.len = len;
+ cram_stats_add(c->stats[DS_RS], len);
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_pad(cram_container *c, cram_slice *s, cram_record *r,
+ int pos, int len, char *base) {
+ cram_feature f;
+ f.S.pos = pos+1;
+ f.S.code = 'P';
+ f.S.len = len;
+ cram_stats_add(c->stats[DS_PD], len);
+ return cram_add_feature(c, s, r, &f);
+}
+
+static int cram_add_insertion(cram_container *c, cram_slice *s, cram_record *r,
+ int pos, int len, char *base) {
+ cram_feature f;
+ f.I.pos = pos+1;
+ if (len == 1) {
+ char b = base ? *base : 'N';
+ f.i.code = 'i';
+ f.i.base = b;
+ cram_stats_add(c->stats[DS_BA], b);
+ } else {
+ f.I.code = 'I';
+ f.I.len = len;
+ f.S.seq_idx = BLOCK_SIZE(s->base_blk);
+ if (base) {
+ BLOCK_APPEND(s->base_blk, base, len);
+ } else {
+ int i;
+ for (i = 0; i < len; i++)
+ BLOCK_APPEND_CHAR(s->base_blk, 'N');
+ }
+ BLOCK_APPEND_CHAR(s->base_blk, '\0');
+ }
+ return cram_add_feature(c, s, r, &f);
+}
+
+/*
+ * Encodes auxiliary data.
+ * Returns the read-group parsed out of the BAM aux fields on success
+ * NULL on failure or no rg present (FIXME)
+ */
+static char *cram_encode_aux_1_0(cram_fd *fd, bam_seq_t *b, cram_container *c,
+ cram_slice *s, cram_record *cr) {
+ char *aux, *tmp, *rg = NULL;
+ int aux_size = bam_blk_size(b) -
+ ((char *)bam_aux(b) - (char *)&bam_ref(b));
+
+ /* Worst case is 1 nul char on every ??:Z: string, so +33% */
+ BLOCK_GROW(s->aux_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_blk);
+
+ aux = (char *)bam_aux(b);
+ cr->TN_idx = s->nTN;
+
+ while (aux[0] != 0) {
+ int32_t i32;
+ int r;
+
+ if (aux[0] == 'R' && aux[1] == 'G' && aux[2] == 'Z') {
+ rg = &aux[3];
+ while (*aux++);
+ continue;
+ }
+ if (aux[0] == 'M' && aux[1] == 'D' && aux[2] == 'Z') {
+ while (*aux++);
+ continue;
+ }
+ if (aux[0] == 'N' && aux[1] == 'M') {
+ switch(aux[2]) {
+ case 'A': case 'C': case 'c': aux+=4; break;
+ case 'I': case 'i': case 'f': aux+=7; break;
+ default:
+ fprintf(stderr, "Unhandled type code for NM tag\n");
+ return NULL;
+ }
+ continue;
+ }
+
+ cr->ntags++;
+
+ i32 = (aux[0]<<16) | (aux[1]<<8) | aux[2];
+ kh_put(s_i2i, c->tags_used, i32, &r);
+ if (-1 == r)
+ return NULL;
+
+ if (s->nTN >= s->aTN) {
+ s->aTN = s->aTN ? s->aTN*2 : 1024;
+ if (!(s->TN = realloc(s->TN, s->aTN * sizeof(*s->TN))))
+ return NULL;
+ }
+ s->TN[s->nTN++] = i32;
+ cram_stats_add(c->stats[DS_TN], i32);
+
+ switch(aux[2]) {
+ case 'A': case 'C': case 'c':
+ aux+=3; //*tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ *tmp++=*aux++;
+ break;
+
+ case 'S': case 's':
+ aux+=3; //*tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ *tmp++=*aux++; *tmp++=*aux++;
+ break;
+
+ case 'I': case 'i': case 'f':
+ aux+=3; //*tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ break;
+
+ case 'd':
+ aux+=3; //*tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ break;
+
+ case 'Z': case 'H':
+ aux+=3; //*tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ while ((*tmp++=*aux++));
+ *tmp++ = '\t'; // stop byte
+ break;
+
+ case 'B': {
+ int type = aux[3], blen;
+ uint32_t count = (uint32_t)((((unsigned char *)aux)[4]<< 0) +
+ (((unsigned char *)aux)[5]<< 8) +
+ (((unsigned char *)aux)[6]<<16) +
+ (((unsigned char *)aux)[7]<<24));
+ // skip TN field
+ aux+=3; //*tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+
+ // We use BYTE_ARRAY_LEN with external length, so store that first
+ switch (type) {
+ case 'c': case 'C':
+ blen = count;
+ break;
+ case 's': case 'S':
+ blen = 2*count;
+ break;
+ case 'i': case 'I': case 'f':
+ blen = 4*count;
+ break;
+ default:
+ fprintf(stderr, "Unknown sub-type '%c' for aux type 'B'\n",
+ type);
+ return NULL;
+
+ }
+
+ tmp += itf8_put(tmp, blen+5);
+
+ *tmp++=*aux++; // sub-type & length
+ *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+
+ // The tag data itself
+ memcpy(tmp, aux, blen); tmp += blen; aux += blen;
+
+ //cram_stats_add(c->aux_B_stats, blen);
+ break;
+ }
+ default:
+ fprintf(stderr, "Unknown aux type '%c'\n", aux[2]);
+ return NULL;
+ }
+ }
+ cram_stats_add(c->stats[DS_TC], cr->ntags);
+
+ cr->aux = BLOCK_SIZE(s->aux_blk);
+ cr->aux_size = (uc *)tmp - (BLOCK_DATA(s->aux_blk) + cr->aux);
+ BLOCK_SIZE(s->aux_blk) = (uc *)tmp - BLOCK_DATA(s->aux_blk);
+ assert(s->aux_blk->byte <= s->aux_blk->alloc);
+
+ return rg;
+}
+
+/*
+ * Encodes auxiliary data. Largely duplicated from above, but done so to
+ * keep it simple and avoid a myriad of version ifs.
+ *
+ * Returns the read-group parsed out of the BAM aux fields on success
+ * NULL on failure or no rg present (FIXME)
+ */
+static char *cram_encode_aux(cram_fd *fd, bam_seq_t *b, cram_container *c,
+ cram_slice *s, cram_record *cr) {
+ char *aux, *orig, *tmp, *rg = NULL;
+ int aux_size = bam_get_l_aux(b);
+ cram_block *td_b = c->comp_hdr->TD_blk;
+ int TD_blk_size = BLOCK_SIZE(td_b), new;
+ char *key;
+ khint_t k;
+
+
+ /* Worst case is 1 nul char on every ??:Z: string, so +33% */
+ BLOCK_GROW(s->aux_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_blk);
+
+
+ orig = aux = (char *)bam_aux(b);
+
+ // Copy aux keys to td_b and aux values to s->aux_blk
+ while (aux - orig < aux_size && aux[0] != 0) {
+ uint32_t i32;
+ int r;
+
+ // RG:Z
+ if (aux[0] == 'R' && aux[1] == 'G' && aux[2] == 'Z') {
+ rg = &aux[3];
+ while (*aux++);
+ continue;
+ }
+
+ // MD:Z
+ if (aux[0] == 'M' && aux[1] == 'D' && aux[2] == 'Z') {
+ if (cr->len && !fd->no_ref && !(cr->flags & BAM_FUNMAP)) {
+ while (*aux++);
+ continue;
+ }
+ }
+
+ // NM:i
+ if (aux[0] == 'N' && aux[1] == 'M') {
+ if (cr->len && !fd->no_ref && !(cr->flags & BAM_FUNMAP)) {
+ switch(aux[2]) {
+ case 'A': case 'C': case 'c': aux+=4; break;
+ case 'S': case 's': aux+=5; break;
+ case 'I': case 'i': case 'f': aux+=7; break;
+ default:
+ fprintf(stderr, "Unhandled type code for NM tag\n");
+ return NULL;
+ }
+ continue;
+ }
+ }
+
+ BLOCK_APPEND(td_b, aux, 3);
+
+ i32 = (aux[0]<<16) | (aux[1]<<8) | aux[2];
+ kh_put(s_i2i, c->tags_used, i32, &r);
+ if (-1 == r)
+ return NULL;
+
+ // BQ:Z
+ if (aux[0] == 'B' && aux[1] == 'Q' && aux[2] == 'Z') {
+ char *tmp;
+ if (!s->aux_BQ_blk)
+ if (!(s->aux_BQ_blk = cram_new_block(EXTERNAL, DS_aux_BQ)))
+ return NULL;
+ BLOCK_GROW(s->aux_BQ_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_BQ_blk);
+ aux += 3;
+ while ((*tmp++=*aux++));
+ *tmp++ = '\t';
+ BLOCK_SIZE(s->aux_BQ_blk) = (uc *)tmp - BLOCK_DATA(s->aux_BQ_blk);
+ continue;
+ }
+
+ // BD:Z
+ if (aux[0] == 'B' && aux[1]=='D' && aux[2] == 'Z') {
+ char *tmp;
+ if (!s->aux_BD_blk)
+ if (!(s->aux_BD_blk = cram_new_block(EXTERNAL, DS_aux_BD)))
+ return NULL;
+ BLOCK_GROW(s->aux_BD_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_BD_blk);
+ aux += 3;
+ while ((*tmp++=*aux++));
+ *tmp++ = '\t';
+ BLOCK_SIZE(s->aux_BD_blk) = (uc *)tmp - BLOCK_DATA(s->aux_BD_blk);
+ continue;
+ }
+
+ // BI:Z
+ if (aux[0] == 'B' && aux[1]=='I' && aux[2] == 'Z') {
+ char *tmp;
+ if (!s->aux_BI_blk)
+ if (!(s->aux_BI_blk = cram_new_block(EXTERNAL, DS_aux_BI)))
+ return NULL;
+ BLOCK_GROW(s->aux_BI_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_BI_blk);
+ aux += 3;
+ while ((*tmp++=*aux++));
+ *tmp++ = '\t';
+ BLOCK_SIZE(s->aux_BI_blk) = (uc *)tmp - BLOCK_DATA(s->aux_BI_blk);
+ continue;
+ }
+
+ // OQ:Z:
+ if (aux[0] == 'O' && aux[1] == 'Q' && aux[2] == 'Z') {
+ char *tmp;
+ if (!s->aux_OQ_blk)
+ if (!(s->aux_OQ_blk = cram_new_block(EXTERNAL, DS_aux_OQ)))
+ return NULL;
+ BLOCK_GROW(s->aux_OQ_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_OQ_blk);
+ aux += 3;
+ while ((*tmp++=*aux++));
+ *tmp++ = '\t';
+ BLOCK_SIZE(s->aux_OQ_blk) = (uc *)tmp - BLOCK_DATA(s->aux_OQ_blk);
+ continue;
+ }
+
+ // FZ:B or ZM:B
+ if ((aux[0] == 'F' && aux[1] == 'Z' && aux[2] == 'B') ||
+ (aux[0] == 'Z' && aux[1] == 'M' && aux[2] == 'B')) {
+ int type = aux[3], blen;
+ uint32_t count = (uint32_t)((((unsigned char *)aux)[4]<< 0) +
+ (((unsigned char *)aux)[5]<< 8) +
+ (((unsigned char *)aux)[6]<<16) +
+ (((unsigned char *)aux)[7]<<24));
+ char *tmp;
+ if (!s->aux_FZ_blk)
+ if (!(s->aux_FZ_blk = cram_new_block(EXTERNAL, DS_aux_FZ)))
+ return NULL;
+ BLOCK_GROW(s->aux_FZ_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_FZ_blk);
+
+ // skip TN field
+ aux+=3;
+
+ // We use BYTE_ARRAY_LEN with external length, so store that first
+ switch (type) {
+ case 'c': case 'C':
+ blen = count;
+ break;
+ case 's': case 'S':
+ blen = 2*count;
+ break;
+ case 'i': case 'I': case 'f':
+ blen = 4*count;
+ break;
+ default:
+ fprintf(stderr, "Unknown sub-type '%c' for aux type 'B'\n",
+ type);
+ return NULL;
+
+ }
+
+ blen += 5; // sub-type & length
+ tmp += itf8_put(tmp, blen);
+
+ // The tag data itself
+ memcpy(tmp, aux, blen); tmp += blen; aux += blen;
+
+ BLOCK_SIZE(s->aux_FZ_blk) = (uc *)tmp - BLOCK_DATA(s->aux_FZ_blk);
+ continue;
+ }
+
+ // Other quality data - {Q2,E2,U2,CQ}:Z and similar
+ if (((aux[0] == 'Q' && aux[1] == '2') ||
+ (aux[0] == 'U' && aux[1] == '2') ||
+ (aux[0] == 'Q' && aux[1] == 'T') ||
+ (aux[0] == 'C' && aux[1] == 'Q')) && aux[2] == 'Z') {
+ char *tmp;
+ if (!s->aux_oq_blk)
+ if (!(s->aux_oq_blk = cram_new_block(EXTERNAL, DS_aux_oq)))
+ return NULL;
+ BLOCK_GROW(s->aux_oq_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_oq_blk);
+ aux += 3;
+ while ((*tmp++=*aux++));
+ *tmp++ = '\t';
+ BLOCK_SIZE(s->aux_oq_blk) = (uc *)tmp - BLOCK_DATA(s->aux_oq_blk);
+ continue;
+ }
+
+ // Other sequence data - {R2,E2,CS,BC,RT}:Z and similar
+ if (((aux[0] == 'R' && aux[1] == '2') ||
+ (aux[0] == 'E' && aux[1] == '2') ||
+ (aux[0] == 'C' && aux[1] == 'S') ||
+ (aux[0] == 'B' && aux[1] == 'C') ||
+ (aux[0] == 'R' && aux[1] == 'T')) && aux[2] == 'Z') {
+ char *tmp;
+ if (!s->aux_os_blk)
+ if (!(s->aux_os_blk = cram_new_block(EXTERNAL, DS_aux_os)))
+ return NULL;
+ BLOCK_GROW(s->aux_os_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_os_blk);
+ aux += 3;
+ while ((*tmp++=*aux++));
+ *tmp++ = '\t';
+ BLOCK_SIZE(s->aux_os_blk) = (uc *)tmp - BLOCK_DATA(s->aux_os_blk);
+ continue;
+ }
+
+
+ switch(aux[2]) {
+ case 'A': case 'C': case 'c':
+ aux+=3;
+ *tmp++=*aux++;
+ break;
+
+ case 'S': case 's':
+ aux+=3;
+ *tmp++=*aux++; *tmp++=*aux++;
+ break;
+
+ case 'I': case 'i': case 'f':
+ aux+=3;
+ *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ break;
+
+ case 'd':
+ aux+=3; //*tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++; *tmp++=*aux++;
+ break;
+
+ case 'Z': case 'H':
+ {
+ char *tmp;
+ if (!s->aux_oz_blk)
+ if (!(s->aux_oz_blk = cram_new_block(EXTERNAL, DS_aux_oz)))
+ return NULL;
+ BLOCK_GROW(s->aux_oz_blk, aux_size*1.34+1);
+ tmp = (char *)BLOCK_END(s->aux_oz_blk);
+ aux += 3;
+ while ((*tmp++=*aux++));
+ *tmp++ = '\t';
+ BLOCK_SIZE(s->aux_oz_blk) = (uc *)tmp -
+ BLOCK_DATA(s->aux_oz_blk);
+ }
+ break;
+
+ case 'B': {
+ int type = aux[3], blen;
+ uint32_t count = (uint32_t)((((unsigned char *)aux)[4]<< 0) +
+ (((unsigned char *)aux)[5]<< 8) +
+ (((unsigned char *)aux)[6]<<16) +
+ (((unsigned char *)aux)[7]<<24));
+ // skip TN field
+ aux+=3;
+
+ // We use BYTE_ARRAY_LEN with external length, so store that first
+ switch (type) {
+ case 'c': case 'C':
+ blen = count;
+ break;
+ case 's': case 'S':
+ blen = 2*count;
+ break;
+ case 'i': case 'I': case 'f':
+ blen = 4*count;
+ break;
+ default:
+ fprintf(stderr, "Unknown sub-type '%c' for aux type 'B'\n",
+ type);
+ return NULL;
+
+ }
+
+ blen += 5; // sub-type & length
+ tmp += itf8_put(tmp, blen);
+
+ // The tag data itself
+ memcpy(tmp, aux, blen); tmp += blen; aux += blen;
+
+ //cram_stats_add(c->aux_B_stats, blen);
+ break;
+ }
+ default:
+ fprintf(stderr, "Unknown aux type '%c'\n", aux[2]);
+ return NULL;
+ }
+ }
+
+ // FIXME: sort BLOCK_DATA(td_b) by char[3] triples
+
+ // And and increment TD hash entry
+ BLOCK_APPEND_CHAR(td_b, 0);
+
+ // Duplicate key as BLOCK_DATA() can be realloced to a new pointer.
+ key = string_ndup(c->comp_hdr->TD_keys,
+ (char *)BLOCK_DATA(td_b) + TD_blk_size,
+ BLOCK_SIZE(td_b) - TD_blk_size);
+ k = kh_put(m_s2i, c->comp_hdr->TD_hash, key, &new);
+ if (new < 0) {
+ return NULL;
+ } else if (new == 0) {
+ BLOCK_SIZE(td_b) = TD_blk_size;
+ } else {
+ kh_val(c->comp_hdr->TD_hash, k) = c->comp_hdr->nTL;
+ c->comp_hdr->nTL++;
+ }
+
+ cr->TL = kh_val(c->comp_hdr->TD_hash, k);
+ cram_stats_add(c->stats[DS_TL], cr->TL);
+
+ cr->aux = BLOCK_SIZE(s->aux_blk);
+ cr->aux_size = (uc *)tmp - (BLOCK_DATA(s->aux_blk) + cr->aux);
+ BLOCK_SIZE(s->aux_blk) = (uc *)tmp - BLOCK_DATA(s->aux_blk);
+ assert(s->aux_blk->byte <= s->aux_blk->alloc);
+
+ return rg;
+}
+
+
+/*
+ * Handles creation of a new container or new slice, flushing any
+ * existing containers when appropriate.
+ *
+ * Really this is next slice, which may or may not lead to a new container.
+ *
+ * Returns cram_container pointer on success
+ * NULL on failure.
+ */
+static cram_container *cram_next_container(cram_fd *fd, bam_seq_t *b) {
+ cram_container *c = fd->ctr;
+ cram_slice *s;
+ int i;
+
+ /* First occurence */
+ if (c->curr_ref == -2)
+ c->curr_ref = bam_ref(b);
+
+ if (c->slice) {
+ s = c->slice;
+ if (c->multi_seq) {
+ s->hdr->ref_seq_id = -2;
+ s->hdr->ref_seq_start = 0;
+ s->hdr->ref_seq_span = 0;
+ } else {
+ s->hdr->ref_seq_id = c->curr_ref;
+ s->hdr->ref_seq_start = c->first_base;
+ s->hdr->ref_seq_span = c->last_base - c->first_base + 1;
+ }
+ s->hdr->num_records = c->curr_rec;
+
+ if (c->curr_slice == 0) {
+ if (c->ref_seq_id != s->hdr->ref_seq_id)
+ c->ref_seq_id = s->hdr->ref_seq_id;
+ c->ref_seq_start = c->first_base;
+ }
+
+ c->curr_slice++;
+ }
+
+ /* Flush container */
+ if (c->curr_slice == c->max_slice ||
+ (bam_ref(b) != c->curr_ref && !c->multi_seq)) {
+ c->ref_seq_span = fd->last_base - c->ref_seq_start + 1;
+ if (fd->verbose)
+ fprintf(stderr, "Flush container %d/%d..%d\n",
+ c->ref_seq_id, c->ref_seq_start,
+ c->ref_seq_start + c->ref_seq_span -1);
+
+ /* Encode slices */
+ if (fd->pool) {
+ if (-1 == cram_flush_container_mt(fd, c))
+ return NULL;
+ } else {
+ if (-1 == cram_flush_container(fd, c))
+ return NULL;
+
+ // Move to sep func, as we need cram_flush_container for
+ // the closing phase to flush the partial container.
+ for (i = 0; i < c->max_slice; i++) {
+ cram_free_slice(c->slices[i]);
+ c->slices[i] = NULL;
+ }
+
+ c->slice = NULL;
+ c->curr_slice = 0;
+
+ /* Easy approach for purposes of freeing stats */
+ cram_free_container(c);
+ }
+
+ c = fd->ctr = cram_new_container(fd->seqs_per_slice,
+ fd->slices_per_container);
+ if (!c)
+ return NULL;
+ c->record_counter = fd->record_counter;
+ c->curr_ref = bam_ref(b);
+ }
+
+ c->last_pos = c->first_base = c->last_base = bam_pos(b)+1;
+
+ /* New slice */
+ c->slice = c->slices[c->curr_slice] =
+ cram_new_slice(MAPPED_SLICE, c->max_rec);
+ if (!c->slice)
+ return NULL;
+
+ if (c->multi_seq) {
+ c->slice->hdr->ref_seq_id = -2;
+ c->slice->hdr->ref_seq_start = 0;
+ c->slice->last_apos = 1;
+ } else {
+ c->slice->hdr->ref_seq_id = bam_ref(b);
+ // wrong for unsorted data, will fix during encoding.
+ c->slice->hdr->ref_seq_start = bam_pos(b)+1;
+ c->slice->last_apos = bam_pos(b)+1;
+ }
+
+ c->curr_rec = 0;
+
+ return c;
+}
+
+/*
+ * Converts a single bam record into a cram record.
+ * Possibly used within a thread.
+ *
+ * Returns 0 on success;
+ * -1 on failure
+ */
+static int process_one_read(cram_fd *fd, cram_container *c,
+ cram_slice *s, cram_record *cr,
+ bam_seq_t *b, int rnum) {
+ int i, fake_qual = -1;
+ char *cp, *rg;
+ char *ref, *seq, *qual;
+
+ // FIXME: multi-ref containers
+
+ ref = c->ref;
+ cr->flags = bam_flag(b);
+ cr->len = bam_seq_len(b);
+
+ //fprintf(stderr, "%s => %d\n", rg ? rg : "\"\"", cr->rg);
+
+ // Fields to resolve later
+ //cr->mate_line; // index to another cram_record
+ //cr->mate_flags; // MF
+ //cr->ntags; // TC
+ cr->ntags = 0; //cram_stats_add(c->stats[DS_TC], cr->ntags);
+ if (CRAM_MAJOR_VERS(fd->version) == 1)
+ rg = cram_encode_aux_1_0(fd, b, c, s, cr);
+ else
+ rg = cram_encode_aux(fd, b, c, s, cr);
+
+ //cr->aux_size = b->blk_size - ((char *)bam_aux(b) - (char *)&bam_ref(b));
+ //cr->aux = DSTRING_LEN(s->aux_ds);
+ //dstring_nappend(s->aux_ds, bam_aux(b), cr->aux_size);
+
+ /* Read group, identified earlier */
+ if (rg) {
+ SAM_RG *brg = sam_hdr_find_rg(fd->header, rg);
+ cr->rg = brg ? brg->id : -1;
+ } else if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ SAM_RG *brg = sam_hdr_find_rg(fd->header, "UNKNOWN");
+ assert(brg);
+ } else {
+ cr->rg = -1;
+ }
+ cram_stats_add(c->stats[DS_RG], cr->rg);
+
+
+ cr->ref_id = bam_ref(b); cram_stats_add(c->stats[DS_RI], cr->ref_id);
+ cram_stats_add(c->stats[DS_BF], fd->cram_flag_swap[cr->flags & 0xfff]);
+
+ // Non reference based encoding means storing the bases verbatim as features, which in
+ // turn means every base also has a quality already stored.
+ if (!fd->no_ref || CRAM_MAJOR_VERS(fd->version) >= 3)
+ cr->cram_flags = CRAM_FLAG_PRESERVE_QUAL_SCORES;
+ else
+ cr->cram_flags = 0;
+
+ if (cr->len <= 0 && CRAM_MAJOR_VERS(fd->version) >= 3)
+ cr->cram_flags |= CRAM_FLAG_NO_SEQ;
+ //cram_stats_add(c->stats[DS_CF], cr->cram_flags & CRAM_FLAG_MASK);
+
+ c->num_bases += cr->len;
+ cr->apos = bam_pos(b)+1;
+ if (c->pos_sorted) {
+ if (cr->apos < s->last_apos) {
+ c->pos_sorted = 0;
+ } else {
+ cram_stats_add(c->stats[DS_AP], cr->apos - s->last_apos);
+ s->last_apos = cr->apos;
+ }
+ } else {
+ //cram_stats_add(c->stats[DS_AP], cr->apos);
+ }
+ c->max_apos += (cr->apos > c->max_apos) * (cr->apos - c->max_apos);
+
+ cr->name = BLOCK_SIZE(s->name_blk);
+ cr->name_len = bam_name_len(b);
+ cram_stats_add(c->stats[DS_RN], cr->name_len);
+
+ BLOCK_APPEND(s->name_blk, bam_name(b), bam_name_len(b));
+
+
+ /*
+ * This seqs_ds is largely pointless and it could reuse the same memory
+ * over and over.
+ * s->base_blk is what we need for encoding.
+ */
+ cr->seq = BLOCK_SIZE(s->seqs_blk);
+ cr->qual = BLOCK_SIZE(s->qual_blk);
+ BLOCK_GROW(s->seqs_blk, cr->len+1);
+ BLOCK_GROW(s->qual_blk, cr->len);
+ seq = cp = (char *)BLOCK_END(s->seqs_blk);
+
+ *seq = 0;
+#ifdef ALLOW_UAC
+ {
+ // Convert seq 2 bases at a time for speed.
+ static const uint16_t code2base[256] = {
+ 15677, 16701, 17213, 19773, 18237, 21053, 21309, 22077,
+ 21565, 22333, 22845, 18493, 19261, 17469, 16957, 20029,
+ 15681, 16705, 17217, 19777, 18241, 21057, 21313, 22081,
+ 21569, 22337, 22849, 18497, 19265, 17473, 16961, 20033,
+ 15683, 16707, 17219, 19779, 18243, 21059, 21315, 22083,
+ 21571, 22339, 22851, 18499, 19267, 17475, 16963, 20035,
+ 15693, 16717, 17229, 19789, 18253, 21069, 21325, 22093,
+ 21581, 22349, 22861, 18509, 19277, 17485, 16973, 20045,
+ 15687, 16711, 17223, 19783, 18247, 21063, 21319, 22087,
+ 21575, 22343, 22855, 18503, 19271, 17479, 16967, 20039,
+ 15698, 16722, 17234, 19794, 18258, 21074, 21330, 22098,
+ 21586, 22354, 22866, 18514, 19282, 17490, 16978, 20050,
+ 15699, 16723, 17235, 19795, 18259, 21075, 21331, 22099,
+ 21587, 22355, 22867, 18515, 19283, 17491, 16979, 20051,
+ 15702, 16726, 17238, 19798, 18262, 21078, 21334, 22102,
+ 21590, 22358, 22870, 18518, 19286, 17494, 16982, 20054,
+ 15700, 16724, 17236, 19796, 18260, 21076, 21332, 22100,
+ 21588, 22356, 22868, 18516, 19284, 17492, 16980, 20052,
+ 15703, 16727, 17239, 19799, 18263, 21079, 21335, 22103,
+ 21591, 22359, 22871, 18519, 19287, 17495, 16983, 20055,
+ 15705, 16729, 17241, 19801, 18265, 21081, 21337, 22105,
+ 21593, 22361, 22873, 18521, 19289, 17497, 16985, 20057,
+ 15688, 16712, 17224, 19784, 18248, 21064, 21320, 22088,
+ 21576, 22344, 22856, 18504, 19272, 17480, 16968, 20040,
+ 15691, 16715, 17227, 19787, 18251, 21067, 21323, 22091,
+ 21579, 22347, 22859, 18507, 19275, 17483, 16971, 20043,
+ 15684, 16708, 17220, 19780, 18244, 21060, 21316, 22084,
+ 21572, 22340, 22852, 18500, 19268, 17476, 16964, 20036,
+ 15682, 16706, 17218, 19778, 18242, 21058, 21314, 22082,
+ 21570, 22338, 22850, 18498, 19266, 17474, 16962, 20034,
+ 15694, 16718, 17230, 19790, 18254, 21070, 21326, 22094,
+ 21582, 22350, 22862, 18510, 19278, 17486, 16974, 20046
+ };
+
+ int l2 = cr->len / 2;
+ unsigned char *from = (unsigned char *)bam_seq(b);
+ uint16_t *cpi = (uint16_t *)cp;
+ cp[0] = 0;
+ for (i = 0; i < l2; i++)
+ cpi[i] = le_int2(code2base[from[i]]);
+ if ((i *= 2) < cr->len)
+ cp[i] = seq_nt16_str[bam_seqi(bam_seq(b), i)];
+ }
+#else
+ for (i = 0; i < cr->len; i++)
+ cp[i] = seq_nt16_str[bam_seqi(bam_seq(b), i)];
+#endif
+ BLOCK_SIZE(s->seqs_blk) += cr->len;
+
+ qual = cp = (char *)bam_qual(b);
+
+ /* Copy and parse */
+ if (!(cr->flags & BAM_FUNMAP)) {
+ uint32_t *cig_to, *cig_from;
+ int apos = cr->apos-1, spos = 0;
+
+ cr->cigar = s->ncigar;
+ cr->ncigar = bam_cigar_len(b);
+ while (cr->cigar + cr->ncigar >= s->cigar_alloc) {
+ s->cigar_alloc = s->cigar_alloc ? s->cigar_alloc*2 : 1024;
+ s->cigar = realloc(s->cigar, s->cigar_alloc * sizeof(*s->cigar));
+ if (!s->cigar)
+ return -1;
+ }
+
+ cig_to = (uint32_t *)s->cigar;
+ cig_from = (uint32_t *)bam_cigar(b);
+
+ cr->feature = 0;
+ cr->nfeature = 0;
+ for (i = 0; i < cr->ncigar; i++) {
+ enum cigar_op cig_op = cig_from[i] & BAM_CIGAR_MASK;
+ uint32_t cig_len = cig_from[i] >> BAM_CIGAR_SHIFT;
+ cig_to[i] = cig_from[i];
+
+ /* Can also generate events from here for CRAM diffs */
+
+ switch (cig_op) {
+ int l;
+
+ // Don't trust = and X ops to be correct.
+ case BAM_CMATCH:
+ case BAM_CBASE_MATCH:
+ case BAM_CBASE_MISMATCH:
+ //fprintf(stderr, "\nBAM_CMATCH\nR: %.*s\nS: %.*s\n",
+ // cig_len, &ref[apos], cig_len, &seq[spos]);
+ l = 0;
+ if (!fd->no_ref && cr->len) {
+ int end = cig_len+apos < c->ref_end
+ ? cig_len : c->ref_end - apos;
+ char *sp = &seq[spos];
+ char *rp = &ref[apos];
+ char *qp = &qual[spos];
+ if (end > cr->len) {
+ fprintf(stderr, "CIGAR and query sequence are of "
+ "different length\n");
+ return -1;
+ }
+ for (l = 0; l < end; l++) {
+ if (rp[l] != sp[l]) {
+ if (!sp[l])
+ break;
+ if (0 && CRAM_MAJOR_VERS(fd->version) >= 3) {
+ // Disabled for the time being as it doesn't
+ // seem to gain us much.
+ int ol=l;
+ while (l<end && rp[l] != sp[l])
+ l++;
+ if (l-ol > 1) {
+ if (cram_add_bases(fd, c, s, cr, spos+ol,
+ l-ol, &seq[spos+ol]))
+ return -1;
+ l--;
+ } else {
+ l = ol;
+ if (cram_add_substitution(fd, c, s, cr,
+ spos+l, sp[l],
+ qp[l], rp[l]))
+ return -1;
+ }
+ } else {
+ if (cram_add_substitution(fd, c, s, cr, spos+l,
+ sp[l], qp[l], rp[l]))
+ return -1;
+ }
+ }
+ }
+ spos += l;
+ apos += l;
+ }
+
+ if (l < cig_len && cr->len) {
+ if (fd->no_ref) {
+ if (CRAM_MAJOR_VERS(fd->version) == 3) {
+ if (cram_add_bases(fd, c, s, cr, spos,
+ cig_len-l, &seq[spos]))
+ return -1;
+ spos += cig_len-l;
+ } else {
+ for (; l < cig_len && seq[spos]; l++, spos++) {
+ if (cram_add_base(fd, c, s, cr, spos,
+ seq[spos], qual[spos]))
+ return -1;
+ }
+ }
+ } else {
+ /* off end of sequence or non-ref based output */
+ for (; l < cig_len && seq[spos]; l++, spos++) {
+ if (cram_add_base(fd, c, s, cr, spos,
+ seq[spos], qual[spos]))
+ return -1;
+ }
+ }
+ apos += cig_len;
+ } else if (!cr->len) {
+ /* Seq "*" */
+ apos += cig_len;
+ spos += cig_len;
+ }
+ break;
+
+ case BAM_CDEL:
+ if (cram_add_deletion(c, s, cr, spos, cig_len, &seq[spos]))
+ return -1;
+ apos += cig_len;
+ break;
+
+ case BAM_CREF_SKIP:
+ if (cram_add_skip(c, s, cr, spos, cig_len, &seq[spos]))
+ return -1;
+ apos += cig_len;
+ break;
+
+ case BAM_CINS:
+ if (cram_add_insertion(c, s, cr, spos, cig_len,
+ cr->len ? &seq[spos] : NULL))
+ return -1;
+ if (fd->no_ref && cr->len) {
+ for (l = 0; l < cig_len; l++, spos++) {
+ cram_add_quality(fd, c, s, cr, spos, qual[spos]);
+ }
+ } else {
+ spos += cig_len;
+ }
+ break;
+
+ case BAM_CSOFT_CLIP:
+ if (cram_add_softclip(c, s, cr, spos, cig_len,
+ cr->len ? &seq[spos] : NULL,
+ fd->version))
+ return -1;
+ if (fd->no_ref &&
+ !(cr->cram_flags & CRAM_FLAG_PRESERVE_QUAL_SCORES)) {
+ if (cr->len) {
+ for (l = 0; l < cig_len; l++, spos++) {
+ cram_add_quality(fd, c, s, cr, spos, qual[spos]);
+ }
+ } else {
+ for (l = 0; l < cig_len; l++, spos++) {
+ cram_add_quality(fd, c, s, cr, spos, -1);
+ }
+ }
+ } else {
+ spos += cig_len;
+ }
+ break;
+
+ case BAM_CHARD_CLIP:
+ if (cram_add_hardclip(c, s, cr, spos, cig_len, &seq[spos]))
+ return -1;
+ break;
+
+ case BAM_CPAD:
+ if (cram_add_pad(c, s, cr, spos, cig_len, &seq[spos]))
+ return -1;
+ break;
+ }
+ }
+ if (cr->len && spos != cr->len) {
+ fprintf(stderr, "CIGAR and query sequence are of different "
+ "length\n");
+ return -1;
+ }
+ fake_qual = spos;
+ cr->aend = fd->no_ref ? apos : MIN(apos, c->ref_end);
+ cram_stats_add(c->stats[DS_FN], cr->nfeature);
+ } else {
+ // Unmapped
+ cr->cram_flags |= CRAM_FLAG_PRESERVE_QUAL_SCORES;
+ cr->cigar = 0;
+ cr->ncigar = 0;
+ cr->nfeature = 0;
+ cr->aend = cr->apos;
+ for (i = 0; i < cr->len; i++)
+ cram_stats_add(c->stats[DS_BA], seq[i]);
+ fake_qual = 0;
+ }
+
+ /*
+ * Append to the qual block now. We do this here as
+ * cram_add_substitution() can generate BA/QS events which need to
+ * be in the qual block before we append the rest of the data.
+ */
+ if (cr->cram_flags & CRAM_FLAG_PRESERVE_QUAL_SCORES) {
+ /* Special case of seq "*" */
+ if (cr->len == 0) {
+ cr->len = fake_qual;
+ BLOCK_GROW(s->qual_blk, cr->len);
+ cp = (char *)BLOCK_END(s->qual_blk);
+ memset(cp, 255, cr->len);
+ } else {
+ BLOCK_GROW(s->qual_blk, cr->len);
+ cp = (char *)BLOCK_END(s->qual_blk);
+ char *from = (char *)&bam_qual(b)[0];
+ char *to = &cp[0];
+ memcpy(to, from, cr->len);
+ //for (i = 0; i < cr->len; i++) cp[i] = from[i];
+ }
+ BLOCK_SIZE(s->qual_blk) += cr->len;
+ } else {
+ if (cr->len == 0)
+ cr->len = fake_qual >= 0 ? fake_qual : cr->aend - cr->apos + 1;
+ }
+
+ cram_stats_add(c->stats[DS_RL], cr->len);
+
+ /* Now we know apos and aend both, update mate-pair information */
+ {
+ int new;
+ khint_t k;
+ int sec = (cr->flags & BAM_FSECONDARY) ? 1 : 0;
+
+ //fprintf(stderr, "Checking %"PRId64"/%.*s\t", rnum,
+ // cr->name_len, DSTRING_STR(s->name_ds)+cr->name);
+ if (cr->flags & BAM_FPAIRED) {
+ char *key = string_ndup(s->pair_keys,
+ (char *)BLOCK_DATA(s->name_blk)+cr->name,
+ cr->name_len);
+ if (!key)
+ return -1;
+
+ k = kh_put(m_s2i, s->pair[sec], key, &new);
+ if (-1 == new)
+ return -1;
+ else if (new > 0)
+ kh_val(s->pair[sec], k) = rnum;
+ } else {
+ new = 1;
+ }
+
+ if (new == 0) {
+ cram_record *p = &s->crecs[kh_val(s->pair[sec], k)];
+ int aleft, aright, sign;
+
+ aleft = MIN(cr->apos, p->apos);
+ aright = MAX(cr->aend, p->aend);
+ if (cr->apos < p->apos) {
+ sign = 1;
+ } else if (cr->apos > p->apos) {
+ sign = -1;
+ } else if (cr->flags & BAM_FREAD1) {
+ sign = 1;
+ } else {
+ sign = -1;
+ }
+
+ //fprintf(stderr, "paired %"PRId64"\n", kh_val(s->pair[sec], k));
+
+ // This vs p: tlen, matepos, flags
+ if (bam_ins_size(b) != sign*(aright-aleft+1))
+ goto detached;
+
+ if (MAX(bam_mate_pos(b)+1, 0) != p->apos)
+ goto detached;
+
+ if (((bam_flag(b) & BAM_FMUNMAP) != 0) !=
+ ((p->flags & BAM_FUNMAP) != 0))
+ goto detached;
+
+ if (((bam_flag(b) & BAM_FMREVERSE) != 0) !=
+ ((p->flags & BAM_FREVERSE) != 0))
+ goto detached;
+
+
+ // p vs this: tlen, matepos, flags
+ if (p->ref_id != cr->ref_id)
+ goto detached;
+
+ if (p->tlen != -sign*(aright-aleft+1))
+ goto detached;
+
+ if (p->mate_pos != cr->apos)
+ goto detached;
+
+ if (((p->flags & BAM_FMUNMAP) != 0) !=
+ ((p->mate_flags & CRAM_M_UNMAP) != 0))
+ goto detached;
+
+ if (((p->flags & BAM_FMREVERSE) != 0) !=
+ ((p->mate_flags & CRAM_M_REVERSE) != 0))
+ goto detached;
+
+ // Supplementary reads are just too ill defined
+ if ((cr->flags & BAM_FSUPPLEMENTARY) ||
+ (p->flags & BAM_FSUPPLEMENTARY))
+ goto detached;
+
+ /*
+ * The fields below are unused when encoding this read as it is
+ * no longer detached. In theory they may get referred to when
+ * processing a 3rd or 4th read in this template?, so we set them
+ * here just to be sure.
+ *
+ * They do not need cram_stats_add() calls those as they are
+ * not emitted.
+ */
+ cr->mate_pos = p->apos;
+ cr->tlen = sign*(aright-aleft+1);
+ cr->mate_flags =
+ ((p->flags & BAM_FMUNMAP) == BAM_FMUNMAP) * CRAM_M_UNMAP +
+ ((p->flags & BAM_FMREVERSE) == BAM_FMREVERSE) * CRAM_M_REVERSE;
+
+ // Decrement statistics aggregated earlier
+ if (p->cram_flags & CRAM_FLAG_STATS_ADDED) {
+ cram_stats_del(c->stats[DS_NP], p->mate_pos);
+ cram_stats_del(c->stats[DS_MF], p->mate_flags);
+ cram_stats_del(c->stats[DS_TS], p->tlen);
+ cram_stats_del(c->stats[DS_NS], p->mate_ref_id);
+ }
+
+ /* Similarly we could correct the p-> values too, but these will no
+ * longer have any code that refers back to them as the new 'p'
+ * for this template is our current 'cr'.
+ */
+ //p->mate_pos = cr->apos;
+ //p->mate_flags =
+ // ((cr->flags & BAM_FMUNMAP) == BAM_FMUNMAP) * CRAM_M_UNMAP +
+ // ((cr->flags & BAM_FMREVERSE) == BAM_FMREVERSE)* CRAM_M_REVERSE;
+ //p->tlen = p->apos - cr->aend;
+
+ // Clear detached from cr flags
+ cr->cram_flags &= ~CRAM_FLAG_DETACHED;
+ cram_stats_add(c->stats[DS_CF], cr->cram_flags & CRAM_FLAG_MASK);
+
+ // Clear detached from p flags and set downstream
+ if (p->cram_flags & CRAM_FLAG_STATS_ADDED) {
+ cram_stats_del(c->stats[DS_CF], p->cram_flags & CRAM_FLAG_MASK);
+ p->cram_flags &= ~CRAM_FLAG_STATS_ADDED;
+ }
+
+ p->cram_flags &= ~CRAM_FLAG_DETACHED;
+ p->cram_flags |= CRAM_FLAG_MATE_DOWNSTREAM;
+ cram_stats_add(c->stats[DS_CF], p->cram_flags & CRAM_FLAG_MASK);
+
+ p->mate_line = rnum - (kh_val(s->pair[sec], k) + 1);
+ cram_stats_add(c->stats[DS_NF], p->mate_line);
+
+ kh_val(s->pair[sec], k) = rnum;
+ } else {
+ detached:
+ //fprintf(stderr, "unpaired\n");
+
+ /* Derive mate flags from this flag */
+ cr->mate_flags = 0;
+ if (bam_flag(b) & BAM_FMUNMAP)
+ cr->mate_flags |= CRAM_M_UNMAP;
+ if (bam_flag(b) & BAM_FMREVERSE)
+ cr->mate_flags |= CRAM_M_REVERSE;
+
+ cram_stats_add(c->stats[DS_MF], cr->mate_flags);
+
+ cr->mate_pos = MAX(bam_mate_pos(b)+1, 0);
+ cram_stats_add(c->stats[DS_NP], cr->mate_pos);
+
+ cr->tlen = bam_ins_size(b);
+ cram_stats_add(c->stats[DS_TS], cr->tlen);
+
+ cr->cram_flags |= CRAM_FLAG_DETACHED;
+ cram_stats_add(c->stats[DS_CF], cr->cram_flags & CRAM_FLAG_MASK);
+ cram_stats_add(c->stats[DS_NS], bam_mate_ref(b));
+
+ cr->cram_flags |= CRAM_FLAG_STATS_ADDED;
+ }
+ }
+
+ cr->mqual = bam_map_qual(b);
+ cram_stats_add(c->stats[DS_MQ], cr->mqual);
+
+ cr->mate_ref_id = bam_mate_ref(b);
+
+ if (!(bam_flag(b) & BAM_FUNMAP)) {
+ if (c->first_base > cr->apos)
+ c->first_base = cr->apos;
+
+ if (c->last_base < cr->aend)
+ c->last_base = cr->aend;
+ }
+
+ return 0;
+}
+
+/*
+ * Write iterator: put BAM format sequences into a CRAM file.
+ * We buffer up a containers worth of data at a time.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_put_bam_seq(cram_fd *fd, bam_seq_t *b) {
+ cram_container *c;
+
+ if (!fd->ctr) {
+ fd->ctr = cram_new_container(fd->seqs_per_slice,
+ fd->slices_per_container);
+ if (!fd->ctr)
+ return -1;
+ fd->ctr->record_counter = fd->record_counter;
+ }
+ c = fd->ctr;
+
+ if (!c->slice || c->curr_rec == c->max_rec ||
+ (bam_ref(b) != c->curr_ref && c->curr_ref >= -1)) {
+ int slice_rec, curr_rec, multi_seq = fd->multi_seq == 1;
+ int curr_ref = c->slice ? c->curr_ref : bam_ref(b);
+
+
+ /*
+ * Start packing slices when we routinely have under 1/4tr full.
+ *
+ * This option isn't available if we choose to embed references
+ * since we can only have one per slice.
+ */
+ if (fd->multi_seq == -1 && c->curr_rec < c->max_rec/4+10 &&
+ fd->last_slice && fd->last_slice < c->max_rec/4+10 &&
+ !fd->embed_ref) {
+ if (fd->verbose && !c->multi_seq)
+ fprintf(stderr, "Multi-ref enabled for this container\n");
+ multi_seq = 1;
+ }
+
+ slice_rec = c->slice_rec;
+ curr_rec = c->curr_rec;
+
+ if (CRAM_MAJOR_VERS(fd->version) == 1 ||
+ c->curr_rec == c->max_rec || fd->multi_seq != 1 || !c->slice) {
+ if (NULL == (c = cram_next_container(fd, b))) {
+ if (fd->ctr) {
+ // prevent cram_close attempting to flush
+ cram_free_container(fd->ctr);
+ fd->ctr = NULL;
+ }
+ return -1;
+ }
+ }
+
+ /*
+ * Due to our processing order, some things we've already done we
+ * cannot easily undo. So when we first notice we should be packing
+ * multiple sequences per container we emit the small partial
+ * container as-is and then start a fresh one in a different mode.
+ */
+ if (multi_seq) {
+ fd->multi_seq = 1;
+ c->multi_seq = 1;
+ c->pos_sorted = 0; // required atm for multi_seq slices
+
+ if (!c->refs_used) {
+ pthread_mutex_lock(&fd->ref_lock);
+ c->refs_used = calloc(fd->refs->nref, sizeof(int));
+ pthread_mutex_unlock(&fd->ref_lock);
+ if (!c->refs_used)
+ return -1;
+ }
+ }
+
+ fd->last_slice = curr_rec - slice_rec;
+ c->slice_rec = c->curr_rec;
+
+ // Have we seen this reference before?
+ if (bam_ref(b) >= 0 && bam_ref(b) != curr_ref && !fd->embed_ref &&
+ !fd->unsorted && multi_seq) {
+
+ if (!c->refs_used) {
+ pthread_mutex_lock(&fd->ref_lock);
+ c->refs_used = calloc(fd->refs->nref, sizeof(int));
+ pthread_mutex_unlock(&fd->ref_lock);
+ if (!c->refs_used)
+ return -1;
+ } else if (c->refs_used && c->refs_used[bam_ref(b)]) {
+ pthread_mutex_lock(&fd->ref_lock);
+ fd->unsorted = 1;
+ pthread_mutex_unlock(&fd->ref_lock);
+ fd->multi_seq = 1;
+ }
+ }
+
+ c->curr_ref = bam_ref(b);
+ if (c->refs_used && c->curr_ref >= 0) c->refs_used[c->curr_ref]++;
+ }
+
+ if (!c->bams) {
+ /* First time through, allocate a set of bam pointers */
+ pthread_mutex_lock(&fd->bam_list_lock);
+ if (fd->bl) {
+ spare_bams *spare = fd->bl;
+ c->bams = spare->bams;
+ fd->bl = spare->next;
+ free(spare);
+ } else {
+ c->bams = calloc(c->max_c_rec, sizeof(bam_seq_t *));
+ if (!c->bams)
+ return -1;
+ }
+ pthread_mutex_unlock(&fd->bam_list_lock);
+ }
+
+ /* Copy or alloc+copy the bam record, for later encoding */
+ if (c->bams[c->curr_c_rec])
+ bam_copy1(c->bams[c->curr_c_rec], b);
+ else
+ c->bams[c->curr_c_rec] = bam_dup(b);
+
+ c->curr_rec++;
+ c->curr_c_rec++;
+ fd->record_counter++;
+
+ return 0;
+}
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*! \file
+ * Include cram.h instead.
+ *
+ * This is an internal part of the CRAM system and is automatically included
+ * when you #include cram.h.
+ *
+ * Implements the encoding portion of CRAM I/O. Also see
+ * cram_codecs.[ch] for the actual encoding functions themselves.
+ */
+
+#ifndef _CRAM_WRITE_H_
+#define _CRAM_WRITE_H_
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/* ----------------------------------------------------------------------
+ * CRAM sequence iterators.
+ */
+
+/*! Write iterator: put BAM format sequences into a CRAM file.
+ *
+ * We buffer up a containers worth of data at a time.
+ *
+ * FIXME: break this into smaller pieces.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_put_bam_seq(cram_fd *fd, bam_seq_t *b);
+
+
+/* ----------------------------------------------------------------------
+ * Internal functions
+ */
+
+/*! INTERNAL:
+ * Encodes a compression header block into a generic cram_block structure.
+ *
+ * @return
+ * Returns cram_block ptr on success;
+ * NULL on failure
+ */
+cram_block *cram_encode_compression_header(cram_fd *fd, cram_container *c,
+ cram_block_compression_hdr *h);
+
+/*! INTERNAL:
+ * Encodes a slice compression header.
+ *
+ * @return
+ * Returns cram_block on success;
+ * NULL on failure
+ */
+cram_block *cram_encode_slice_header(cram_fd *fd, cram_slice *s);
+
+/*! INTERNAL:
+ * Encodes all slices in a container into blocks.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ *
+ * FIXME: separate into encode_container and write_container. Ideally
+ * we should be able to do read_container / write_container or
+ * decode_container / encode_container.
+ */
+int cram_encode_container(cram_fd *fd, cram_container *c);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/*
+Copyright (c) 2015 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*! \file
+ * External CRAM interface.
+ *
+ * Internally we're happy to use macros and to grub around in the cram
+ * structures. This isn't very sustainable for an externally usable
+ * ABI though, so we have anonymous structs and accessor functions too
+ * to permit software such as samtools reheader to manipulate cram
+ * containers and blocks in a robust manner.
+ */
+
+#include <config.h>
+
+#include "htslib/hfile.h"
+#include "cram/cram.h"
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_fd
+ */
+SAM_hdr *cram_fd_get_header(cram_fd *fd) { return fd->header; }
+void cram_fd_set_header(cram_fd *fd, SAM_hdr *hdr) { fd->header = hdr; }
+
+int cram_fd_get_version(cram_fd *fd) { return fd->version; }
+void cram_fd_set_version(cram_fd *fd, int vers) { fd->version = vers; }
+
+int cram_major_vers(cram_fd *fd) { return CRAM_MAJOR_VERS(fd->version); }
+int cram_minor_vers(cram_fd *fd) { return CRAM_MINOR_VERS(fd->version); }
+
+hFILE *cram_fd_get_fp(cram_fd *fd) { return fd->fp; }
+void cram_fd_set_fp(cram_fd *fd, hFILE *fp) { fd->fp = fp; }
+
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_container
+ */
+int32_t cram_container_get_length(cram_container *c) {
+ return c->length;
+}
+
+void cram_container_set_length(cram_container *c, int32_t length) {
+ c->length = length;
+}
+
+
+int32_t cram_container_get_num_blocks(cram_container *c) {
+ return c->num_blocks;
+}
+
+void cram_container_set_num_blocks(cram_container *c, int32_t num_blocks) {
+ c->num_blocks = num_blocks;
+}
+
+
+/* Returns the landmarks[] array and the number of elements
+ * in num_landmarks.
+ */
+int32_t *cram_container_get_landmarks(cram_container *c, int32_t *num_landmarks) {
+ *num_landmarks = c->num_landmarks;
+ return c->landmark;
+}
+
+/* Sets the landmarks[] array (pointer copy, not a memory dup) and
+ * num_landmarks value.
+ */
+void cram_container_set_landmarks(cram_container *c, int32_t num_landmarks,
+ int32_t *landmarks) {
+ c->num_landmarks = num_landmarks;
+ c->landmark = landmarks;
+}
+
+
+/* Returns true if the container is empty (EOF marker) */
+int cram_container_is_empty(cram_fd *fd) {
+ return fd->empty_container;
+}
+
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_block_compression_hdr
+ */
+
+/*
+ * Utility function to edit an RG id.
+ * This is only possible if there is one single RG value used and it
+ * is in the container compression header using HUFFMAN or BETA
+ * codec. In this case it is essentially hard coded and needs no
+ * editing of external (or worse, CORE) blocks.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+// Or arbitrary set compression header constant?
+
+static int cram_block_compression_hdr_set_DS(cram_block_compression_hdr *ch,
+ int ds, int new_rg) {
+ if (!ch || !ch->codecs[ds])
+ return -1;
+
+ switch (ch->codecs[ds]->codec) {
+ case E_HUFFMAN:
+ if (ch->codecs[ds]->huffman.ncodes != 1)
+ return -1;
+ ch->codecs[ds]->huffman.codes[0].symbol = new_rg;
+ return 0;
+
+ case E_BETA:
+ if (ch->codecs[ds]->beta.nbits != 0)
+ return -1;
+ ch->codecs[ds]->beta.offset = -new_rg;
+ return 0;
+
+ default:
+ return -1;
+ }
+
+ return 0;
+}
+
+int cram_block_compression_hdr_set_rg(cram_block_compression_hdr *ch, int new_rg) {
+ return cram_block_compression_hdr_set_DS(ch, DS_RG, new_rg);
+}
+
+/*
+ * Converts a cram_block_compression_hdr struct used for decoding to
+ * one used for encoding. Maybe this should be a transparent
+ * operation applied on-demand.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_block_compression_hdr_decoder2encoder(cram_fd *fd,
+ cram_block_compression_hdr *ch) {
+ int i;
+
+ if (!ch)
+ return -1;
+
+ for (i = 0; i < DS_END; i++) {
+ cram_codec *co = ch->codecs[i];
+ if (!co)
+ continue;
+
+ if (-1 == cram_codec_decoder2encoder(fd, co))
+ return -1;
+ }
+
+ return 0;
+}
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_slice
+ */
+int32_t cram_slice_hdr_get_num_blocks(cram_block_slice_hdr *hdr) {
+ return hdr->num_blocks;
+}
+
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_block
+ */
+int32_t cram_block_get_content_id(cram_block *b) { return b->content_id; }
+int32_t cram_block_get_comp_size(cram_block *b) { return b->comp_size; }
+int32_t cram_block_get_uncomp_size(cram_block *b) { return b->uncomp_size; }
+int32_t cram_block_get_crc32(cram_block *b) { return b->crc32; }
+void * cram_block_get_data(cram_block *b) { return BLOCK_DATA(b); }
+int32_t cram_block_get_size(cram_block *b) { return BLOCK_SIZE(b); }
+enum cram_content_type cram_block_get_content_type(cram_block *b) {
+ return b->content_type;
+}
+
+void cram_block_set_content_id(cram_block *b, int32_t id) { b->content_id = id; }
+void cram_block_set_comp_size(cram_block *b, int32_t size) { b->comp_size = size; }
+void cram_block_set_uncomp_size(cram_block *b, int32_t size) { b->uncomp_size = size; }
+void cram_block_set_crc32(cram_block *b, int32_t crc) { b->crc32 = crc; }
+void cram_block_set_data(cram_block *b, void *data) { BLOCK_DATA(b) = data; }
+void cram_block_set_size(cram_block *b, int32_t size) { BLOCK_SIZE(b) = size; }
+
+int cram_block_append(cram_block *b, void *data, int size) {
+ BLOCK_APPEND(b, data, size);
+ return BLOCK_DATA(b) ? 0 : -1; // It'll do for now...
+}
+void cram_block_update_size(cram_block *b) { BLOCK_UPLEN(b); }
+
+// Offset is known as "size" internally, but it can be confusing.
+size_t cram_block_get_offset(cram_block *b) { return BLOCK_SIZE(b); }
+void cram_block_set_offset(cram_block *b, size_t offset) { BLOCK_SIZE(b) = offset; }
+
+
+/*
+ * Copies the blocks representing the next num_slice slices from a
+ * container from 'in' to 'out'. It is expected that the file pointer
+ * is just after the read of the cram_container and cram compression
+ * header.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_copy_slice(cram_fd *in, cram_fd *out, int32_t num_slice) {
+ int32_t i, j;
+
+ for (i = 0; i < num_slice; i++) {
+ cram_block *blk;
+ cram_block_slice_hdr *hdr;
+
+ if (!(blk = cram_read_block(in)))
+ return -1;
+ if (!(hdr = cram_decode_slice_header(in, blk))) {
+ cram_free_block(blk);
+ return -1;
+ }
+ if (cram_write_block(out, blk) != 0) {
+ cram_free_block(blk);
+ return -1;
+ }
+ cram_free_block(blk);
+
+ int num_blocks = cram_slice_hdr_get_num_blocks(hdr);
+ for (j = 0; j < num_blocks; j++) {
+ blk = cram_read_block(in);
+ if (!blk || cram_write_block(out, blk) != 0) {
+ if (blk) cram_free_block(blk);
+ return -1;
+ }
+ cram_free_block(blk);
+ }
+ cram_free_slice_header(hdr);
+ }
+
+ return 0;
+}
+
+/*
+ * Renumbers RG numbers in a cram compression header.
+ *
+ * CRAM stores RG as the Nth number in the header, rather than a
+ * string holding the ID: tag. This is smaller in space, but means
+ * "samtools cat" to join files together that contain single but
+ * different RG lines needs a way of renumbering them.
+ *
+ * The file descriptor is expected to be immediately after the
+ * cram_container structure (ie before the cram compression header).
+ * Due to the nature of the CRAM format, this needs to read and write
+ * the blocks itself. Note that there may be multiple slices within
+ * the container, meaning multiple compression headers to manipulate.
+ * Changing RG may change the size of the compression header and
+ * therefore the length field in the container. Hence we rewrite all
+ * blocks just incase and also emit the adjusted container.
+ *
+ * The current implementation can only cope with renumbering a single
+ * RG (and only then if it is using HUFFMAN or BETA codecs). In
+ * theory it *may* be possible to renumber multiple RGs if they use
+ * HUFFMAN to the CORE block or use an external block unshared by any
+ * other data series. So we have an API that can be upgraded to
+ * support this, but do not implement it for now. An example
+ * implementation of RG as an EXTERNAL block would be to find that
+ * block and rewrite it, returning the number of blocks consumed.
+ *
+ * Returns 0 on success;
+ * -1 if unable to edit;
+ * -2 on other errors (eg I/O).
+ */
+int cram_transcode_rg(cram_fd *in, cram_fd *out,
+ cram_container *c,
+ int nrg, int *in_rg, int *out_rg) {
+ int new_rg = *out_rg, old_size, new_size;
+ cram_block *o_blk, *n_blk;
+ cram_block_compression_hdr *ch;
+
+ if (nrg != 1) {
+ fprintf(stderr, "[%s] ERROR: not implemented for nrg != 1\n",
+ __func__);
+ return -2;
+ }
+
+ // Produce a new block holding the updated compression header,
+ // with RG transcoded to a new value. (Single only supported.)
+ o_blk = cram_read_block(in);
+ old_size = cram_block_size(o_blk);
+ ch = cram_decode_compression_header(in, o_blk);
+ if (cram_block_compression_hdr_set_rg(ch, new_rg) != 0)
+ return -1;
+ cram_block_compression_hdr_decoder2encoder(in, ch);
+ n_blk = cram_encode_compression_header(in, c, ch);
+ cram_free_compression_header(ch);
+
+ /*
+ * Warning: this has internal knowledge of the cram compression
+ * header format.
+ *
+ * The decoder doesn't set c->tags_used, so the encoder puts a two
+ * byte blank segment. This means n_blk is too short. We skip
+ * through the decoded old block (o_blk) and copy from there.
+ */
+ char *cp = cram_block_get_data(o_blk);
+ char *op = cp;
+ char *endp = cp + cram_block_get_uncomp_size(o_blk);
+ //fprintf(stderr, "sz = %d\n", (int)(endp-cp));
+ int32_t i32;
+
+ cp += safe_itf8_get(cp, endp, &i32);
+ cp += i32;
+ cp += safe_itf8_get(cp, endp, &i32);
+ cp += i32;
+ op = cp;
+ cp += safe_itf8_get(cp, endp, &i32);
+ i32 += (cp-op);
+
+ //fprintf(stderr, "remaining %d bytes\n", i32);
+ cram_block_set_size(n_blk, cram_block_get_size(n_blk)-2);
+ cram_block_append(n_blk, op, i32);
+ cram_block_update_size(n_blk);
+
+ new_size = cram_block_size(n_blk);
+
+ //fprintf(stderr, "size %d -> %d\n", old_size, new_size);
+
+ // Now we've constructedthe updated compression header,
+ // amend the container too (it may have changed size).
+ int32_t *landmarks, num_landmarks;
+ landmarks = cram_container_get_landmarks(c, &num_landmarks);
+
+ if (old_size != new_size) {
+ int diff = new_size - old_size, j;
+
+ for (j = 0; j < num_landmarks; j++)
+ landmarks[j] += diff;
+ //cram_container_set_landmarks(c, num_landmarks, landmarks);
+ cram_container_set_length(c, cram_container_get_length(c) + diff);
+ }
+
+ // Finally write it all out; container, compression header,
+ // and then all the remaining slice blocks.
+ if (cram_write_container(out, c) != 0)
+ return -2;
+
+ cram_write_block(out, n_blk);
+ cram_free_block(o_blk);
+ cram_free_block(n_blk);
+
+ // Container num_blocks can be invalid, due to a bug.
+ // Instead we iterate in slice context instead.
+ return cram_copy_slice(in, out, num_landmarks);
+}
--- /dev/null
+/*
+Copyright (c) 2013-2014 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+ * The index is a gzipped tab-delimited text file with one line per slice.
+ * The columns are:
+ * 1: reference number (0 to N-1, as per BAM ref_id)
+ * 2: reference position of 1st read in slice (1..?)
+ * 3: number of reads in slice
+ * 4: offset of container start (relative to end of SAM header, so 1st
+ * container is offset 0).
+ * 5: slice number within container (ie which landmark).
+ *
+ * In memory, we hold this in a nested containment list. Each list element is
+ * a cram_index struct. Each element in turn can contain its own list of
+ * cram_index structs.
+ *
+ * Any start..end range which is entirely contained within another (and
+ * earlier as it is sorted) range will be held within it. This ensures that
+ * the outer list will never have containments and we can safely do a
+ * binary search to find the first range which overlaps any given coordinate.
+ */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <errno.h>
+#include <assert.h>
+#include <stdlib.h>
+#include <string.h>
+#include <zlib.h>
+#include <sys/types.h>
+#include <sys/stat.h>
+#include <math.h>
+#include <ctype.h>
+
+#include "htslib/hfile.h"
+#include "hts_internal.h"
+#include "cram/cram.h"
+#include "cram/os.h"
+#include "cram/zfio.h"
+
+#if 0
+static void dump_index_(cram_index *e, int level) {
+ int i, n;
+ n = printf("%*s%d / %d .. %d, ", level*4, "", e->refid, e->start, e->end);
+ printf("%*soffset %"PRId64"\n", MAX(0,50-n), "", e->offset);
+ for (i = 0; i < e->nslice; i++) {
+ dump_index_(&e->e[i], level+1);
+ }
+}
+
+static void dump_index(cram_fd *fd) {
+ int i;
+ for (i = 0; i < fd->index_sz; i++) {
+ dump_index_(&fd->index[i], 0);
+ }
+}
+#endif
+
+static int kget_int32(kstring_t *k, size_t *pos, int32_t *val_p) {
+ int sign = 1;
+ int32_t val = 0;
+ size_t p = *pos;
+
+ while (p < k->l && (k->s[p] == ' ' || k->s[p] == '\t'))
+ p++;
+
+ if (p < k->l && k->s[p] == '-')
+ sign = -1, p++;
+
+ if (p >= k->l || !(k->s[p] >= '0' && k->s[p] <= '9'))
+ return -1;
+
+ while (p < k->l && k->s[p] >= '0' && k->s[p] <= '9')
+ val = val*10 + k->s[p++]-'0';
+
+ *pos = p;
+ *val_p = sign*val;
+
+ return 0;
+}
+
+static int kget_int64(kstring_t *k, size_t *pos, int64_t *val_p) {
+ int sign = 1;
+ int64_t val = 0;
+ size_t p = *pos;
+
+ while (p < k->l && (k->s[p] == ' ' || k->s[p] == '\t'))
+ p++;
+
+ if (p < k->l && k->s[p] == '-')
+ sign = -1, p++;
+
+ if (p >= k->l || !(k->s[p] >= '0' && k->s[p] <= '9'))
+ return -1;
+
+ while (p < k->l && k->s[p] >= '0' && k->s[p] <= '9')
+ val = val*10 + k->s[p++]-'0';
+
+ *pos = p;
+ *val_p = sign*val;
+
+ return 0;
+}
+
+/*
+ * Loads a CRAM .crai index into memory.
+ *
+ * Returns 0 for success
+ * -1 for failure
+ */
+int cram_index_load(cram_fd *fd, const char *fn, const char *fn_idx) {
+ char *fn2 = NULL;
+ char buf[65536];
+ ssize_t len;
+ kstring_t kstr = {0};
+ FILE *fp;
+ cram_index *idx;
+ cram_index **idx_stack = NULL, *ep, e;
+ int idx_stack_alloc = 0, idx_stack_ptr = 0;
+ size_t pos = 0;
+
+ /* Check if already loaded */
+ if (fd->index)
+ return 0;
+
+ fd->index = calloc((fd->index_sz = 1), sizeof(*fd->index));
+ if (!fd->index)
+ return -1;
+
+ idx = &fd->index[0];
+ idx->refid = -1;
+ idx->start = INT_MIN;
+ idx->end = INT_MAX;
+
+ idx_stack = calloc(++idx_stack_alloc, sizeof(*idx_stack));
+ idx_stack[idx_stack_ptr] = idx;
+
+ if (!fn_idx) {
+ fn2 = hts_idx_getfn(fn, ".crai");
+ if (!fn2) {
+ free(idx_stack);
+ return -1;
+ }
+ fn_idx = fn2;
+ }
+
+ if (!(fp = fopen(fn_idx, "r"))) {
+ perror(fn_idx);
+ free(idx_stack);
+ free(fn2);
+ return -1;
+ }
+
+ // Load the file into memory
+ while ((len = fread(buf, 1, 65536, fp)) > 0)
+ kputsn(buf, len, &kstr);
+ if (len < 0 || kstr.l < 2) {
+ if (kstr.s)
+ free(kstr.s);
+ free(idx_stack);
+ free(fn2);
+ return -1;
+ }
+
+ if (fclose(fp)) {
+ if (kstr.s)
+ free(kstr.s);
+ free(idx_stack);
+ free(fn2);
+ return -1;
+ }
+
+
+ // Uncompress if required
+ if (kstr.s[0] == 31 && (uc)kstr.s[1] == 139) {
+ size_t l;
+ char *s = zlib_mem_inflate(kstr.s, kstr.l, &l);
+ free(kstr.s);
+ if (!s) {
+ free(idx_stack);
+ free(fn2);
+ return -1;
+ }
+ kstr.s = s;
+ kstr.l = l;
+ kstr.m = l; // conservative estimate of the size allocated
+ kputsn("", 0, &kstr); // ensure kstr.s is NUL-terminated
+ }
+
+
+ // Parse it line at a time
+ do {
+ /* 1.1 layout */
+ if (kget_int32(&kstr, &pos, &e.refid) == -1) {
+ free(kstr.s); free(idx_stack); free(fn2); return -1;
+ }
+ if (kget_int32(&kstr, &pos, &e.start) == -1) {
+ free(kstr.s); free(idx_stack); free(fn2); return -1;
+ }
+ if (kget_int32(&kstr, &pos, &e.end) == -1) {
+ free(kstr.s); free(idx_stack); free(fn2); return -1;
+ }
+ if (kget_int64(&kstr, &pos, &e.offset) == -1) {
+ free(kstr.s); free(idx_stack); free(fn2); return -1;
+ }
+ if (kget_int32(&kstr, &pos, &e.slice) == -1) {
+ free(kstr.s); free(idx_stack); free(fn2); return -1;
+ }
+ if (kget_int32(&kstr, &pos, &e.len) == -1) {
+ free(kstr.s); free(idx_stack); free(fn2); return -1;
+ }
+
+ e.end += e.start-1;
+ //printf("%d/%d..%d\n", e.refid, e.start, e.end);
+
+ if (e.refid < -1) {
+ free(kstr.s);
+ free(idx_stack);
+ free(fn2);
+ fprintf(stderr, "Malformed index file, refid %d\n", e.refid);
+ return -1;
+ }
+
+ if (e.refid != idx->refid) {
+ if (fd->index_sz < e.refid+2) {
+ size_t index_end = fd->index_sz * sizeof(*fd->index);
+ fd->index_sz = e.refid+2;
+ fd->index = realloc(fd->index,
+ fd->index_sz * sizeof(*fd->index));
+ memset(((char *)fd->index) + index_end, 0,
+ fd->index_sz * sizeof(*fd->index) - index_end);
+ }
+ idx = &fd->index[e.refid+1];
+ idx->refid = e.refid;
+ idx->start = INT_MIN;
+ idx->end = INT_MAX;
+ idx->nslice = idx->nalloc = 0;
+ idx->e = NULL;
+ idx_stack[(idx_stack_ptr = 0)] = idx;
+ }
+
+ while (!(e.start >= idx->start && e.end <= idx->end) || idx->end == 0) {
+ idx = idx_stack[--idx_stack_ptr];
+ }
+
+ // Now contains, so append
+ if (idx->nslice+1 >= idx->nalloc) {
+ idx->nalloc = idx->nalloc ? idx->nalloc*2 : 16;
+ idx->e = realloc(idx->e, idx->nalloc * sizeof(*idx->e));
+ }
+
+ e.nalloc = e.nslice = 0; e.e = NULL;
+ *(ep = &idx->e[idx->nslice++]) = e;
+ idx = ep;
+
+ if (++idx_stack_ptr >= idx_stack_alloc) {
+ idx_stack_alloc *= 2;
+ idx_stack = realloc(idx_stack, idx_stack_alloc*sizeof(*idx_stack));
+ }
+ idx_stack[idx_stack_ptr] = idx;
+
+ while (pos < kstr.l && kstr.s[pos] != '\n')
+ pos++;
+ pos++;
+ } while (pos < kstr.l);
+
+ free(idx_stack);
+ free(kstr.s);
+ free(fn2);
+
+ // dump_index(fd);
+
+ return 0;
+}
+
+static void cram_index_free_recurse(cram_index *e) {
+ if (e->e) {
+ int i;
+ for (i = 0; i < e->nslice; i++) {
+ cram_index_free_recurse(&e->e[i]);
+ }
+ free(e->e);
+ }
+}
+
+void cram_index_free(cram_fd *fd) {
+ int i;
+
+ if (!fd->index)
+ return;
+
+ for (i = 0; i < fd->index_sz; i++) {
+ cram_index_free_recurse(&fd->index[i]);
+ }
+ free(fd->index);
+
+ fd->index = NULL;
+}
+
+/*
+ * Searches the index for the first slice overlapping a reference ID
+ * and position, or one immediately preceding it if none is found in
+ * the index to overlap this position. (Our index may have missing
+ * entries, but we require at least one per reference.)
+ *
+ * If the index finds multiple slices overlapping this position we
+ * return the first one only. Subsequent calls should specifying
+ * "from" as the last slice we checked to find the next one. Otherwise
+ * set "from" to be NULL to find the first one.
+ *
+ * Returns the cram_index pointer on sucess
+ * NULL on failure
+ */
+cram_index *cram_index_query(cram_fd *fd, int refid, int pos,
+ cram_index *from) {
+ int i, j, k;
+ cram_index *e;
+
+ if (refid+1 < 0 || refid+1 >= fd->index_sz)
+ return NULL;
+
+ if (!from)
+ from = &fd->index[refid+1];
+
+ // Ref with nothing aligned against it.
+ if (!from->e)
+ return NULL;
+
+ // This sequence is covered by the index, so binary search to find
+ // the optimal starting block.
+ i = 0, j = fd->index[refid+1].nslice-1;
+ for (k = j/2; k != i; k = (j-i)/2 + i) {
+ if (from->e[k].refid > refid) {
+ j = k;
+ continue;
+ }
+
+ if (from->e[k].refid < refid) {
+ i = k;
+ continue;
+ }
+
+ if (from->e[k].start >= pos) {
+ j = k;
+ continue;
+ }
+
+ if (from->e[k].start < pos) {
+ i = k;
+ continue;
+ }
+ }
+ // i==j or i==j-1. Check if j is better.
+ if (j >= 0 && from->e[j].start < pos && from->e[j].refid == refid)
+ i = j;
+
+ /* The above found *a* bin overlapping, but not necessarily the first */
+ while (i > 0 && from->e[i-1].end >= pos)
+ i--;
+
+ /* We may be one bin before the optimum, so check */
+ while (i+1 < from->nslice &&
+ (from->e[i].refid < refid ||
+ from->e[i].end < pos))
+ i++;
+
+ e = &from->e[i];
+
+ return e;
+}
+
+
+/*
+ * Skips to a container overlapping the start coordinate listed in
+ * cram_range.
+ *
+ * In theory we call cram_index_query multiple times, once per slice
+ * overlapping the range. However slices may be absent from the index
+ * which makes this problematic. Instead we find the left-most slice
+ * and then read from then on, skipping decoding of slices and/or
+ * whole containers when they don't overlap the specified cram_range.
+ *
+ * Returns 0 on success
+ * -1 on general failure
+ * -2 on no-data (empty chromosome)
+ */
+int cram_seek_to_refpos(cram_fd *fd, cram_range *r) {
+ cram_index *e;
+
+ // Ideally use an index, so see if we have one.
+ if ((e = cram_index_query(fd, r->refid, r->start, NULL))) {
+ if (0 != cram_seek(fd, e->offset, SEEK_SET))
+ if (0 != cram_seek(fd, e->offset - fd->first_container, SEEK_CUR))
+ return -1;
+ } else {
+ // Absent from index, but this most likely means it simply has no data.
+ return -2;
+ }
+
+ if (fd->ctr) {
+ cram_free_container(fd->ctr);
+ fd->ctr = NULL;
+ fd->ooc = 0;
+ }
+
+ return 0;
+}
+
+
+/*
+ * A specialised form of cram_index_build (below) that deals with slices
+ * having multiple references in this (ref_id -2). In this scenario we
+ * decode the slice to look at the RI data series instead.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+static int cram_index_build_multiref(cram_fd *fd,
+ cram_container *c,
+ cram_slice *s,
+ zfp *fp,
+ off_t cpos,
+ int32_t landmark,
+ int sz) {
+ int i, ref = -2, ref_start = 0, ref_end;
+ char buf[1024];
+
+ if (0 != cram_decode_slice(fd, c, s, fd->header))
+ return -1;
+
+ ref_end = INT_MIN;
+ for (i = 0; i < s->hdr->num_records; i++) {
+ if (s->crecs[i].ref_id == ref) {
+ if (ref_end < s->crecs[i].aend)
+ ref_end = s->crecs[i].aend;
+ continue;
+ }
+
+ if (ref != -2) {
+ sprintf(buf, "%d\t%d\t%d\t%"PRId64"\t%d\t%d\n",
+ ref, ref_start, ref_end - ref_start + 1,
+ (int64_t)cpos, landmark, sz);
+ zfputs(buf, fp);
+ }
+
+ ref = s->crecs[i].ref_id;
+ ref_start = s->crecs[i].apos;
+ ref_end = INT_MIN;
+ }
+
+ if (ref != -2) {
+ sprintf(buf, "%d\t%d\t%d\t%"PRId64"\t%d\t%d\n",
+ ref, ref_start, ref_end - ref_start + 1,
+ (int64_t)cpos, landmark, sz);
+ zfputs(buf, fp);
+ }
+
+ return 0;
+}
+
+/*
+ * Builds an index file.
+ *
+ * fd is a newly opened cram file that we wish to index.
+ * fn_base is the filename of the associated CRAM file.
+ * fn_idx is the filename of the index file to be written;
+ * if NULL, we add ".crai" to fn_base to get the index filename.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_index_build(cram_fd *fd, const char *fn_base, const char *fn_idx) {
+ cram_container *c;
+ off_t cpos, spos, hpos;
+ zfp *fp;
+ kstring_t fn_idx_str = {0};
+
+ if (! fn_idx) {
+ kputs(fn_base, &fn_idx_str);
+ kputs(".crai", &fn_idx_str);
+ fn_idx = fn_idx_str.s;
+ }
+
+ if (!(fp = zfopen(fn_idx, "wz"))) {
+ perror(fn_idx);
+ free(fn_idx_str.s);
+ return -1;
+ }
+
+ free(fn_idx_str.s);
+
+ cpos = htell(fd->fp);
+ while ((c = cram_read_container(fd))) {
+ int j;
+
+ if (fd->err) {
+ perror("Cram container read");
+ return -1;
+ }
+
+ hpos = htell(fd->fp);
+
+ if (!(c->comp_hdr_block = cram_read_block(fd)))
+ return -1;
+ assert(c->comp_hdr_block->content_type == COMPRESSION_HEADER);
+
+ c->comp_hdr = cram_decode_compression_header(fd, c->comp_hdr_block);
+ if (!c->comp_hdr)
+ return -1;
+
+ // 2.0 format
+ for (j = 0; j < c->num_landmarks; j++) {
+ char buf[1024];
+ cram_slice *s;
+ int sz;
+
+ spos = htell(fd->fp);
+ assert(spos - cpos - c->offset == c->landmark[j]);
+
+ if (!(s = cram_read_slice(fd))) {
+ zfclose(fp);
+ return -1;
+ }
+
+ sz = (int)(htell(fd->fp) - spos);
+
+ if (s->hdr->ref_seq_id == -2) {
+ cram_index_build_multiref(fd, c, s, fp,
+ cpos, c->landmark[j], sz);
+ } else {
+ sprintf(buf, "%d\t%d\t%d\t%"PRId64"\t%d\t%d\n",
+ s->hdr->ref_seq_id, s->hdr->ref_seq_start,
+ s->hdr->ref_seq_span, (int64_t)cpos,
+ c->landmark[j], sz);
+ zfputs(buf, fp);
+ }
+
+ cram_free_slice(s);
+ }
+
+ cpos = htell(fd->fp);
+ assert(cpos == hpos + c->length);
+
+ cram_free_container(c);
+ }
+ if (fd->err) {
+ zfclose(fp);
+ return -1;
+ }
+
+
+ return (zfclose(fp) >= 0)? 0 : -1;
+}
--- /dev/null
+/*
+Copyright (c) 2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _CRAM_INDEX_H_
+#define _CRAM_INDEX_H_
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*
+ * Loads a CRAM .crai index into memory.
+ * Returns 0 for success
+ * -1 for failure
+ */
+int cram_index_load(cram_fd *fd, const char *fn, const char *fn_idx);
+
+void cram_index_free(cram_fd *fd);
+
+/*
+ * Searches the index for the first slice overlapping a reference ID
+ * and position.
+ *
+ * Returns the cram_index pointer on sucess
+ * NULL on failure
+ */
+cram_index *cram_index_query(cram_fd *fd, int refid, int pos, cram_index *frm);
+
+/*
+ * Skips to a container overlapping the start coordinate listed in
+ * cram_range.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_seek_to_refpos(cram_fd *fd, cram_range *r);
+
+void cram_index_free(cram_fd *fd);
+
+/*
+ * Skips to a container overlapping the start coordinate listed in
+ * cram_range.
+ *
+ * In theory we call cram_index_query multiple times, once per slice
+ * overlapping the range. However slices may be absent from the index
+ * which makes this problematic. Instead we find the left-most slice
+ * and then read from then on, skipping decoding of slices and/or
+ * whole containers when they don't overlap the specified cram_range.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_seek_to_refpos(cram_fd *fd, cram_range *r);
+
+/*
+ * Builds an index file.
+ *
+ * fd is a newly opened cram file that we wish to index.
+ * fn_base is the filename of the associated CRAM file.
+ * fn_idx is the filename of the index file to be written;
+ * if NULL, we add ".crai" to fn_base to get the index filename.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_index_build(cram_fd *fd, const char *fn_base, const char *fn_idx);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/*
+Copyright (c) 2012-2014 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+ * CRAM I/O primitives.
+ *
+ * - ITF8 encoding and decoding.
+ * - Block based I/O
+ * - Zlib inflating and deflating (memory)
+ * - CRAM basic data structure reading and writing
+ * - File opening / closing
+ * - Reference sequence handling
+ */
+
+/*
+ * TODO: BLOCK_GROW, BLOCK_RESIZE, BLOCK_APPEND and itf8_put_blk all need
+ * a way to return errors for when malloc fails.
+ */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <errno.h>
+#include <assert.h>
+#include <stdlib.h>
+#include <string.h>
+#include <unistd.h>
+#include <zlib.h>
+#ifdef HAVE_LIBBZ2
+#include <bzlib.h>
+#endif
+#ifdef HAVE_LIBLZMA
+#include <lzma.h>
+#endif
+#include <sys/types.h>
+#include <sys/stat.h>
+#include <math.h>
+#include <ctype.h>
+#include <time.h>
+
+#include "cram/cram.h"
+#include "cram/os.h"
+#include "htslib/hts.h"
+#include "cram/open_trace_file.h"
+#include "cram/rANS_static.h"
+
+//#define REF_DEBUG
+
+#ifdef REF_DEBUG
+#include <sys/syscall.h>
+#define gettid() (int)syscall(SYS_gettid)
+
+#define RP(...) fprintf (stderr, __VA_ARGS__)
+#else
+#define RP(...)
+#endif
+
+#include "htslib/hfile.h"
+#include "htslib/bgzf.h"
+#include "htslib/faidx.h"
+
+#define TRIAL_SPAN 50
+#define NTRIALS 3
+
+
+/* ----------------------------------------------------------------------
+ * ITF8 encoding and decoding.
+ *
+* Also see the itf8_get and itf8_put macros in cram_io.h
+ */
+
+/*
+ * LEGACY: consider using itf8_decode_crc.
+ *
+ * Reads an integer in ITF-8 encoding from 'cp' and stores it in
+ * *val.
+ *
+ * Returns the number of bytes read on success
+ * -1 on failure
+ */
+int itf8_decode(cram_fd *fd, int32_t *val_p) {
+ static int nbytes[16] = {
+ 0,0,0,0, 0,0,0,0, // 0000xxxx - 0111xxxx
+ 1,1,1,1, // 1000xxxx - 1011xxxx
+ 2,2, // 1100xxxx - 1101xxxx
+ 3, // 1110xxxx
+ 4, // 1111xxxx
+ };
+
+ static int nbits[16] = {
+ 0x7f, 0x7f, 0x7f, 0x7f, 0x7f, 0x7f, 0x7f, 0x7f, // 0000xxxx - 0111xxxx
+ 0x3f, 0x3f, 0x3f, 0x3f, // 1000xxxx - 1011xxxx
+ 0x1f, 0x1f, // 1100xxxx - 1101xxxx
+ 0x0f, // 1110xxxx
+ 0x0f, // 1111xxxx
+ };
+
+ int32_t val = hgetc(fd->fp);
+ if (val == -1)
+ return -1;
+
+ int i = nbytes[val>>4];
+ val &= nbits[val>>4];
+
+ switch(i) {
+ case 0:
+ *val_p = val;
+ return 1;
+
+ case 1:
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val;
+ return 2;
+
+ case 2:
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val;
+ return 3;
+
+ case 3:
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val;
+ return 4;
+
+ case 4: // really 3.5 more, why make it different?
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<4) | (((unsigned char)hgetc(fd->fp)) & 0x0f);
+ *val_p = val;
+ }
+
+ return 5;
+}
+
+int itf8_decode_crc(cram_fd *fd, int32_t *val_p, uint32_t *crc) {
+ static int nbytes[16] = {
+ 0,0,0,0, 0,0,0,0, // 0000xxxx - 0111xxxx
+ 1,1,1,1, // 1000xxxx - 1011xxxx
+ 2,2, // 1100xxxx - 1101xxxx
+ 3, // 1110xxxx
+ 4, // 1111xxxx
+ };
+
+ static int nbits[16] = {
+ 0x7f, 0x7f, 0x7f, 0x7f, 0x7f, 0x7f, 0x7f, 0x7f, // 0000xxxx - 0111xxxx
+ 0x3f, 0x3f, 0x3f, 0x3f, // 1000xxxx - 1011xxxx
+ 0x1f, 0x1f, // 1100xxxx - 1101xxxx
+ 0x0f, // 1110xxxx
+ 0x0f, // 1111xxxx
+ };
+ unsigned char c[5];
+
+ int32_t val = hgetc(fd->fp);
+ if (val == -1)
+ return -1;
+
+ c[0]=val;
+
+ int i = nbytes[val>>4];
+ val &= nbits[val>>4];
+
+ switch(i) {
+ case 0:
+ *val_p = val;
+ *crc = crc32(*crc, c, 1);
+ return 1;
+
+ case 1:
+ val = (val<<8) | (c[1]=hgetc(fd->fp));
+ *val_p = val;
+ *crc = crc32(*crc, c, 2);
+ return 2;
+
+ case 2:
+ val = (val<<8) | (c[1]=hgetc(fd->fp));
+ val = (val<<8) | (c[2]=hgetc(fd->fp));
+ *val_p = val;
+ *crc = crc32(*crc, c, 3);
+ return 3;
+
+ case 3:
+ val = (val<<8) | (c[1]=hgetc(fd->fp));
+ val = (val<<8) | (c[2]=hgetc(fd->fp));
+ val = (val<<8) | (c[3]=hgetc(fd->fp));
+ *val_p = val;
+ *crc = crc32(*crc, c, 4);
+ return 4;
+
+ case 4: // really 3.5 more, why make it different?
+ val = (val<<8) | (c[1]=hgetc(fd->fp));
+ val = (val<<8) | (c[2]=hgetc(fd->fp));
+ val = (val<<8) | (c[3]=hgetc(fd->fp));
+ val = (val<<4) | (((c[4]=hgetc(fd->fp))) & 0x0f);
+ *val_p = val;
+ *crc = crc32(*crc, c, 5);
+ }
+
+ return 5;
+}
+
+/*
+ * Encodes and writes a single integer in ITF-8 format.
+ * Returns 0 on success
+ * -1 on failure
+ */
+int itf8_encode(cram_fd *fd, int32_t val) {
+ char buf[5];
+ int len = itf8_put(buf, val);
+ return hwrite(fd->fp, buf, len) == len ? 0 : -1;
+}
+
+const int itf8_bytes[16] = {
+ 1, 1, 1, 1, 1, 1, 1, 1,
+ 2, 2, 2, 2, 3, 3, 4, 5
+};
+
+#ifndef ITF8_MACROS
+/*
+ * As above, but decoding from memory
+ */
+int itf8_get(char *cp, int32_t *val_p) {
+ unsigned char *up = (unsigned char *)cp;
+
+ if (up[0] < 0x80) {
+ *val_p = up[0];
+ return 1;
+ } else if (up[0] < 0xc0) {
+ *val_p = ((up[0] <<8) | up[1]) & 0x3fff;
+ return 2;
+ } else if (up[0] < 0xe0) {
+ *val_p = ((up[0]<<16) | (up[1]<< 8) | up[2]) & 0x1fffff;
+ return 3;
+ } else if (up[0] < 0xf0) {
+ *val_p = ((up[0]<<24) | (up[1]<<16) | (up[2]<<8) | up[3]) & 0x0fffffff;
+ return 4;
+ } else {
+ *val_p = ((up[0] & 0x0f)<<28) | (up[1]<<20) | (up[2]<<12) | (up[3]<<4) | (up[4] & 0x0f);
+ return 5;
+ }
+}
+
+/*
+ * Stores a value to memory in ITF-8 format.
+ *
+ * Returns the number of bytes required to store the number.
+ * This is a maximum of 5 bytes.
+ */
+int itf8_put(char *cp, int32_t val) {
+ if (!(val & ~0x00000007f)) { // 1 byte
+ *cp = val;
+ return 1;
+ } else if (!(val & ~0x00003fff)) { // 2 byte
+ *cp++ = (val >> 8 ) | 0x80;
+ *cp = val & 0xff;
+ return 2;
+ } else if (!(val & ~0x01fffff)) { // 3 byte
+ *cp++ = (val >> 16) | 0xc0;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 3;
+ } else if (!(val & ~0x0fffffff)) { // 4 byte
+ *cp++ = (val >> 24) | 0xe0;
+ *cp++ = (val >> 16) & 0xff;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 4;
+ } else { // 5 byte
+ *cp++ = 0xf0 | ((val>>28) & 0xff);
+ *cp++ = (val >> 20) & 0xff;
+ *cp++ = (val >> 12) & 0xff;
+ *cp++ = (val >> 4 ) & 0xff;
+ *cp = val & 0x0f;
+ return 5;
+ }
+}
+#endif
+
+/* 64-bit itf8 variant */
+int ltf8_put(char *cp, int64_t val) {
+ if (!(val & ~((1LL<<7)-1))) {
+ *cp = val;
+ return 1;
+ } else if (!(val & ~((1LL<<(6+8))-1))) {
+ *cp++ = (val >> 8 ) | 0x80;
+ *cp = val & 0xff;
+ return 2;
+ } else if (!(val & ~((1LL<<(5+2*8))-1))) {
+ *cp++ = (val >> 16) | 0xc0;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 3;
+ } else if (!(val & ~((1LL<<(4+3*8))-1))) {
+ *cp++ = (val >> 24) | 0xe0;
+ *cp++ = (val >> 16) & 0xff;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 4;
+ } else if (!(val & ~((1LL<<(3+4*8))-1))) {
+ *cp++ = (val >> 32) | 0xf0;
+ *cp++ = (val >> 24) & 0xff;
+ *cp++ = (val >> 16) & 0xff;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 5;
+ } else if (!(val & ~((1LL<<(2+5*8))-1))) {
+ *cp++ = (val >> 40) | 0xf8;
+ *cp++ = (val >> 32) & 0xff;
+ *cp++ = (val >> 24) & 0xff;
+ *cp++ = (val >> 16) & 0xff;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 6;
+ } else if (!(val & ~((1LL<<(1+6*8))-1))) {
+ *cp++ = (val >> 48) | 0xfc;
+ *cp++ = (val >> 40) & 0xff;
+ *cp++ = (val >> 32) & 0xff;
+ *cp++ = (val >> 24) & 0xff;
+ *cp++ = (val >> 16) & 0xff;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 7;
+ } else if (!(val & ~((1LL<<(7*8))-1))) {
+ *cp++ = (val >> 56) | 0xfe;
+ *cp++ = (val >> 48) & 0xff;
+ *cp++ = (val >> 40) & 0xff;
+ *cp++ = (val >> 32) & 0xff;
+ *cp++ = (val >> 24) & 0xff;
+ *cp++ = (val >> 16) & 0xff;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 8;
+ } else {
+ *cp++ = 0xff;
+ *cp++ = (val >> 56) & 0xff;
+ *cp++ = (val >> 48) & 0xff;
+ *cp++ = (val >> 40) & 0xff;
+ *cp++ = (val >> 32) & 0xff;
+ *cp++ = (val >> 24) & 0xff;
+ *cp++ = (val >> 16) & 0xff;
+ *cp++ = (val >> 8 ) & 0xff;
+ *cp = val & 0xff;
+ return 9;
+ }
+}
+
+int ltf8_get(char *cp, int64_t *val_p) {
+ unsigned char *up = (unsigned char *)cp;
+
+ if (up[0] < 0x80) {
+ *val_p = up[0];
+ return 1;
+ } else if (up[0] < 0xc0) {
+ *val_p = (((uint64_t)up[0]<< 8) |
+ (uint64_t)up[1]) & (((1LL<<(6+8)))-1);
+ return 2;
+ } else if (up[0] < 0xe0) {
+ *val_p = (((uint64_t)up[0]<<16) |
+ ((uint64_t)up[1]<< 8) |
+ (uint64_t)up[2]) & ((1LL<<(5+2*8))-1);
+ return 3;
+ } else if (up[0] < 0xf0) {
+ *val_p = (((uint64_t)up[0]<<24) |
+ ((uint64_t)up[1]<<16) |
+ ((uint64_t)up[2]<< 8) |
+ (uint64_t)up[3]) & ((1LL<<(4+3*8))-1);
+ return 4;
+ } else if (up[0] < 0xf8) {
+ *val_p = (((uint64_t)up[0]<<32) |
+ ((uint64_t)up[1]<<24) |
+ ((uint64_t)up[2]<<16) |
+ ((uint64_t)up[3]<< 8) |
+ (uint64_t)up[4]) & ((1LL<<(3+4*8))-1);
+ return 5;
+ } else if (up[0] < 0xfc) {
+ *val_p = (((uint64_t)up[0]<<40) |
+ ((uint64_t)up[1]<<32) |
+ ((uint64_t)up[2]<<24) |
+ ((uint64_t)up[3]<<16) |
+ ((uint64_t)up[4]<< 8) |
+ (uint64_t)up[5]) & ((1LL<<(2+5*8))-1);
+ return 6;
+ } else if (up[0] < 0xfe) {
+ *val_p = (((uint64_t)up[0]<<48) |
+ ((uint64_t)up[1]<<40) |
+ ((uint64_t)up[2]<<32) |
+ ((uint64_t)up[3]<<24) |
+ ((uint64_t)up[4]<<16) |
+ ((uint64_t)up[5]<< 8) |
+ (uint64_t)up[6]) & ((1LL<<(1+6*8))-1);
+ return 7;
+ } else if (up[0] < 0xff) {
+ *val_p = (((uint64_t)up[1]<<48) |
+ ((uint64_t)up[2]<<40) |
+ ((uint64_t)up[3]<<32) |
+ ((uint64_t)up[4]<<24) |
+ ((uint64_t)up[5]<<16) |
+ ((uint64_t)up[6]<< 8) |
+ (uint64_t)up[7]) & ((1LL<<(7*8))-1);
+ return 8;
+ } else {
+ *val_p = (((uint64_t)up[1]<<56) |
+ ((uint64_t)up[2]<<48) |
+ ((uint64_t)up[3]<<40) |
+ ((uint64_t)up[4]<<32) |
+ ((uint64_t)up[5]<<24) |
+ ((uint64_t)up[6]<<16) |
+ ((uint64_t)up[7]<< 8) |
+ (uint64_t)up[8]);
+ return 9;
+ }
+}
+
+/*
+ * LEGACY: consider using ltf8_decode_crc.
+ */
+int ltf8_decode(cram_fd *fd, int64_t *val_p) {
+ int c = hgetc(fd->fp);
+ int64_t val = (unsigned char)c;
+ if (c == -1)
+ return -1;
+
+ if (val < 0x80) {
+ *val_p = val;
+ return 1;
+
+ } else if (val < 0xc0) {
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val & (((1LL<<(6+8)))-1);
+ return 2;
+
+ } else if (val < 0xe0) {
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val & ((1LL<<(5+2*8))-1);
+ return 3;
+
+ } else if (val < 0xf0) {
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val & ((1LL<<(4+3*8))-1);
+ return 4;
+
+ } else if (val < 0xf8) {
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val & ((1LL<<(3+4*8))-1);
+ return 5;
+
+ } else if (val < 0xfc) {
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val & ((1LL<<(2+5*8))-1);
+ return 6;
+
+ } else if (val < 0xfe) {
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val & ((1LL<<(1+6*8))-1);
+ return 7;
+
+ } else if (val < 0xff) {
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val & ((1LL<<(7*8))-1);
+ return 8;
+
+ } else {
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ val = (val<<8) | (unsigned char)hgetc(fd->fp);
+ *val_p = val;
+ }
+
+ return 9;
+}
+
+int ltf8_decode_crc(cram_fd *fd, int64_t *val_p, uint32_t *crc) {
+ unsigned char c[9];
+ int64_t val = (unsigned char)hgetc(fd->fp);
+ if (val == -1)
+ return -1;
+
+ c[0] = val;
+
+ if (val < 0x80) {
+ *val_p = val;
+ *crc = crc32(*crc, c, 1);
+ return 1;
+
+ } else if (val < 0xc0) {
+ val = (val<<8) | (c[1]=hgetc(fd->fp));;
+ *val_p = val & (((1LL<<(6+8)))-1);
+ *crc = crc32(*crc, c, 2);
+ return 2;
+
+ } else if (val < 0xe0) {
+ val = (val<<8) | (c[1]=hgetc(fd->fp));;
+ val = (val<<8) | (c[2]=hgetc(fd->fp));;
+ *val_p = val & ((1LL<<(5+2*8))-1);
+ *crc = crc32(*crc, c, 3);
+ return 3;
+
+ } else if (val < 0xf0) {
+ val = (val<<8) | (c[1]=hgetc(fd->fp));;
+ val = (val<<8) | (c[2]=hgetc(fd->fp));;
+ val = (val<<8) | (c[3]=hgetc(fd->fp));;
+ *val_p = val & ((1LL<<(4+3*8))-1);
+ *crc = crc32(*crc, c, 4);
+ return 4;
+
+ } else if (val < 0xf8) {
+ val = (val<<8) | (c[1]=hgetc(fd->fp));;
+ val = (val<<8) | (c[2]=hgetc(fd->fp));;
+ val = (val<<8) | (c[3]=hgetc(fd->fp));;
+ val = (val<<8) | (c[4]=hgetc(fd->fp));;
+ *val_p = val & ((1LL<<(3+4*8))-1);
+ *crc = crc32(*crc, c, 5);
+ return 5;
+
+ } else if (val < 0xfc) {
+ val = (val<<8) | (c[1]=hgetc(fd->fp));;
+ val = (val<<8) | (c[2]=hgetc(fd->fp));;
+ val = (val<<8) | (c[3]=hgetc(fd->fp));;
+ val = (val<<8) | (c[4]=hgetc(fd->fp));;
+ val = (val<<8) | (c[5]=hgetc(fd->fp));;
+ *val_p = val & ((1LL<<(2+5*8))-1);
+ *crc = crc32(*crc, c, 6);
+ return 6;
+
+ } else if (val < 0xfe) {
+ val = (val<<8) | (c[1]=hgetc(fd->fp));;
+ val = (val<<8) | (c[2]=hgetc(fd->fp));;
+ val = (val<<8) | (c[3]=hgetc(fd->fp));;
+ val = (val<<8) | (c[4]=hgetc(fd->fp));;
+ val = (val<<8) | (c[5]=hgetc(fd->fp));;
+ val = (val<<8) | (c[6]=hgetc(fd->fp));;
+ *val_p = val & ((1LL<<(1+6*8))-1);
+ *crc = crc32(*crc, c, 7);
+ return 7;
+
+ } else if (val < 0xff) {
+ val = (val<<8) | (c[1]=hgetc(fd->fp));;
+ val = (val<<8) | (c[2]=hgetc(fd->fp));;
+ val = (val<<8) | (c[3]=hgetc(fd->fp));;
+ val = (val<<8) | (c[4]=hgetc(fd->fp));;
+ val = (val<<8) | (c[5]=hgetc(fd->fp));;
+ val = (val<<8) | (c[6]=hgetc(fd->fp));;
+ val = (val<<8) | (c[7]=hgetc(fd->fp));;
+ *val_p = val & ((1LL<<(7*8))-1);
+ *crc = crc32(*crc, c, 8);
+ return 8;
+
+ } else {
+ val = (val<<8) | (c[1]=hgetc(fd->fp));;
+ val = (val<<8) | (c[2]=hgetc(fd->fp));;
+ val = (val<<8) | (c[3]=hgetc(fd->fp));;
+ val = (val<<8) | (c[4]=hgetc(fd->fp));;
+ val = (val<<8) | (c[5]=hgetc(fd->fp));;
+ val = (val<<8) | (c[6]=hgetc(fd->fp));;
+ val = (val<<8) | (c[7]=hgetc(fd->fp));;
+ val = (val<<8) | (c[8]=hgetc(fd->fp));;
+ *crc = crc32(*crc, c, 9);
+ *val_p = val;
+ }
+
+ return 9;
+}
+
+/*
+ * Pushes a value in ITF8 format onto the end of a block.
+ * This shouldn't be used for high-volume data as it is not the fastest
+ * method.
+ *
+ * Returns the number of bytes written
+ */
+int itf8_put_blk(cram_block *blk, int val) {
+ char buf[5];
+ int sz;
+
+ sz = itf8_put(buf, val);
+ BLOCK_APPEND(blk, buf, sz);
+ return sz;
+}
+
+/*
+ * Decodes a 32-bit little endian value from fd and stores in val.
+ *
+ * Returns the number of bytes read on success
+ * -1 on failure
+ */
+int int32_decode(cram_fd *fd, int32_t *val) {
+ int32_t i;
+ if (4 != hread(fd->fp, &i, 4))
+ return -1;
+
+ *val = le_int4(i);
+ return 4;
+}
+
+/*
+ * Encodes a 32-bit little endian value 'val' and writes to fd.
+ *
+ * Returns the number of bytes written on success
+ * -1 on failure
+ */
+int int32_encode(cram_fd *fd, int32_t val) {
+ val = le_int4(val);
+ if (4 != hwrite(fd->fp, &val, 4))
+ return -1;
+
+ return 4;
+}
+
+/* As int32_decoded/encode, but from/to blocks instead of cram_fd */
+int int32_get_blk(cram_block *b, int32_t *val) {
+ if (b->uncomp_size - BLOCK_SIZE(b) < 4)
+ return -1;
+
+ *val =
+ b->data[b->byte ] |
+ (b->data[b->byte+1] << 8) |
+ (b->data[b->byte+2] << 16) |
+ (b->data[b->byte+3] << 24);
+ BLOCK_SIZE(b) += 4;
+ return 4;
+}
+
+/* As int32_decoded/encode, but from/to blocks instead of cram_fd */
+int int32_put_blk(cram_block *b, int32_t val) {
+ unsigned char cp[4];
+ cp[0] = ( val & 0xff);
+ cp[1] = ((val>>8) & 0xff);
+ cp[2] = ((val>>16) & 0xff);
+ cp[3] = ((val>>24) & 0xff);
+
+ BLOCK_APPEND(b, cp, 4);
+ return b->data ? 0 : -1;
+}
+
+/* ----------------------------------------------------------------------
+ * zlib compression code - from Gap5's tg_iface_g.c
+ * They're static here as they're only used within the cram_compress_block
+ * and cram_uncompress_block functions, which are the external interface.
+ */
+char *zlib_mem_inflate(char *cdata, size_t csize, size_t *size) {
+ z_stream s;
+ unsigned char *data = NULL; /* Uncompressed output */
+ int data_alloc = 0;
+ int err;
+
+ /* Starting point at uncompressed size, and scale after that */
+ data = malloc(data_alloc = csize*1.2+100);
+ if (!data)
+ return NULL;
+
+ /* Initialise zlib stream */
+ s.zalloc = Z_NULL; /* use default allocation functions */
+ s.zfree = Z_NULL;
+ s.opaque = Z_NULL;
+ s.next_in = (unsigned char *)cdata;
+ s.avail_in = csize;
+ s.total_in = 0;
+ s.next_out = data;
+ s.avail_out = data_alloc;
+ s.total_out = 0;
+
+ //err = inflateInit(&s);
+ err = inflateInit2(&s, 15 + 32);
+ if (err != Z_OK) {
+ fprintf(stderr, "zlib inflateInit error: %s\n", s.msg);
+ free(data);
+ return NULL;
+ }
+
+ /* Decode to 'data' array */
+ for (;s.avail_in;) {
+ unsigned char *data_tmp;
+ int alloc_inc;
+
+ s.next_out = &data[s.total_out];
+ err = inflate(&s, Z_NO_FLUSH);
+ if (err == Z_STREAM_END)
+ break;
+
+ if (err != Z_OK) {
+ fprintf(stderr, "zlib inflate error: %s\n", s.msg);
+ if (data)
+ free(data);
+ return NULL;
+ }
+
+ /* More to come, so realloc based on growth so far */
+ alloc_inc = (double)s.avail_in/s.total_in * s.total_out + 100;
+ data = realloc((data_tmp = data), data_alloc += alloc_inc);
+ if (!data) {
+ free(data_tmp);
+ return NULL;
+ }
+ s.avail_out += alloc_inc;
+ }
+ inflateEnd(&s);
+
+ *size = s.total_out;
+ return (char *)data;
+}
+
+static char *zlib_mem_deflate(char *data, size_t size, size_t *cdata_size,
+ int level, int strat) {
+ z_stream s;
+ unsigned char *cdata = NULL; /* Compressed output */
+ int cdata_alloc = 0;
+ int cdata_pos = 0;
+ int err;
+
+ cdata = malloc(cdata_alloc = size*1.05+100);
+ if (!cdata)
+ return NULL;
+ cdata_pos = 0;
+
+ /* Initialise zlib stream */
+ s.zalloc = Z_NULL; /* use default allocation functions */
+ s.zfree = Z_NULL;
+ s.opaque = Z_NULL;
+ s.next_in = (unsigned char *)data;
+ s.avail_in = size;
+ s.total_in = 0;
+ s.next_out = cdata;
+ s.avail_out = cdata_alloc;
+ s.total_out = 0;
+ s.data_type = Z_BINARY;
+
+ err = deflateInit2(&s, level, Z_DEFLATED, 15|16, 9, strat);
+ if (err != Z_OK) {
+ fprintf(stderr, "zlib deflateInit2 error: %s\n", s.msg);
+ return NULL;
+ }
+
+ /* Encode to 'cdata' array */
+ for (;s.avail_in;) {
+ s.next_out = &cdata[cdata_pos];
+ s.avail_out = cdata_alloc - cdata_pos;
+ if (cdata_alloc - cdata_pos <= 0) {
+ fprintf(stderr, "Deflate produced larger output than expected. Abort\n");
+ return NULL;
+ }
+ err = deflate(&s, Z_NO_FLUSH);
+ cdata_pos = cdata_alloc - s.avail_out;
+ if (err != Z_OK) {
+ fprintf(stderr, "zlib deflate error: %s\n", s.msg);
+ break;
+ }
+ }
+ if (deflate(&s, Z_FINISH) != Z_STREAM_END) {
+ fprintf(stderr, "zlib deflate error: %s\n", s.msg);
+ }
+ *cdata_size = s.total_out;
+
+ if (deflateEnd(&s) != Z_OK) {
+ fprintf(stderr, "zlib deflate error: %s\n", s.msg);
+ }
+ return (char *)cdata;
+}
+
+#ifdef HAVE_LIBLZMA
+/* ------------------------------------------------------------------------ */
+/*
+ * Data compression routines using liblzma (xz)
+ *
+ * On a test set this shrunk the main db from 136157104 bytes to 114796168, but
+ * caused tg_index to grow from 2m43.707s to 15m3.961s. Exporting as bfastq
+ * went from 18.3s to 36.3s. So decompression suffers too, but not as bad
+ * as compression times.
+ *
+ * For now we disable this functionality. If it's to be reenabled make sure you
+ * improve the mem_inflate implementation as it's just a test hack at the
+ * moment.
+ */
+
+static char *lzma_mem_deflate(char *data, size_t size, size_t *cdata_size,
+ int level) {
+ char *out;
+ size_t out_size = lzma_stream_buffer_bound(size);
+ *cdata_size = 0;
+
+ out = malloc(out_size);
+
+ /* Single call compression */
+ if (LZMA_OK != lzma_easy_buffer_encode(level, LZMA_CHECK_CRC32, NULL,
+ (uint8_t *)data, size,
+ (uint8_t *)out, cdata_size,
+ out_size))
+ return NULL;
+
+ return out;
+}
+
+static char *lzma_mem_inflate(char *cdata, size_t csize, size_t *size) {
+ lzma_stream strm = LZMA_STREAM_INIT;
+ size_t out_size = 0, out_pos = 0;
+ char *out = NULL;
+ int r;
+
+ /* Initiate the decoder */
+ if (LZMA_OK != lzma_stream_decoder(&strm, 50000000, 0))
+ return NULL;
+
+ /* Decode loop */
+ strm.avail_in = csize;
+ strm.next_in = (uint8_t *)cdata;
+
+ for (;strm.avail_in;) {
+ if (strm.avail_in > out_size - out_pos) {
+ out_size += strm.avail_in * 4 + 32768;
+ out = realloc(out, out_size);
+ }
+ strm.avail_out = out_size - out_pos;
+ strm.next_out = (uint8_t *)&out[out_pos];
+
+ r = lzma_code(&strm, LZMA_RUN);
+ if (LZMA_OK != r && LZMA_STREAM_END != r) {
+ fprintf(stderr, "r=%d\n", r);
+ fprintf(stderr, "mem=%"PRId64"d\n", (int64_t)lzma_memusage(&strm));
+ return NULL;
+ }
+
+ out_pos = strm.total_out;
+
+ if (r == LZMA_STREAM_END)
+ break;
+ }
+
+ /* finish up any unflushed data; necessary? */
+ r = lzma_code(&strm, LZMA_FINISH);
+ if (r != LZMA_OK && r != LZMA_STREAM_END) {
+ fprintf(stderr, "r=%d\n", r);
+ return NULL;
+ }
+
+ out = realloc(out, strm.total_out);
+ *size = strm.total_out;
+
+ lzma_end(&strm);
+
+ return out;
+}
+#endif
+
+/* ----------------------------------------------------------------------
+ * CRAM blocks - the dynamically growable data block. We have code to
+ * create, update, (un)compress and read/write.
+ *
+ * These are derived from the deflate_interlaced.c blocks, but with the
+ * CRAM extension of content types and IDs.
+ */
+
+/*
+ * Allocates a new cram_block structure with a specified content_type and
+ * id.
+ *
+ * Returns block pointer on success
+ * NULL on failure
+ */
+cram_block *cram_new_block(enum cram_content_type content_type,
+ int content_id) {
+ cram_block *b = malloc(sizeof(*b));
+ if (!b)
+ return NULL;
+ b->method = b->orig_method = RAW;
+ b->content_type = content_type;
+ b->content_id = content_id;
+ b->comp_size = 0;
+ b->uncomp_size = 0;
+ b->data = NULL;
+ b->alloc = 0;
+ b->byte = 0;
+ b->bit = 7; // MSB
+
+ return b;
+}
+
+/*
+ * Reads a block from a cram file.
+ * Returns cram_block pointer on success.
+ * NULL on failure
+ */
+cram_block *cram_read_block(cram_fd *fd) {
+ cram_block *b = malloc(sizeof(*b));
+ unsigned char c;
+ uint32_t crc = 0;
+ if (!b)
+ return NULL;
+
+ //fprintf(stderr, "Block at %d\n", (int)ftell(fd->fp));
+
+ if (-1 == (b->method = hgetc(fd->fp))) { free(b); return NULL; }
+ c = b->method; crc = crc32(crc, &c, 1);
+ if (-1 == (b->content_type= hgetc(fd->fp))) { free(b); return NULL; }
+ c = b->content_type; crc = crc32(crc, &c, 1);
+ if (-1 == itf8_decode_crc(fd, &b->content_id, &crc)) { free(b); return NULL; }
+ if (-1 == itf8_decode_crc(fd, &b->comp_size, &crc)) { free(b); return NULL; }
+ if (-1 == itf8_decode_crc(fd, &b->uncomp_size, &crc)) { free(b); return NULL; }
+
+ // fprintf(stderr, " method %d, ctype %d, cid %d, csize %d, ucsize %d\n",
+ // b->method, b->content_type, b->content_id, b->comp_size, b->uncomp_size);
+
+ if (b->method == RAW) {
+ b->alloc = b->uncomp_size;
+ if (!(b->data = malloc(b->uncomp_size))){ free(b); return NULL; }
+ if (b->uncomp_size != hread(fd->fp, b->data, b->uncomp_size)) {
+ free(b->data);
+ free(b);
+ return NULL;
+ }
+ } else {
+ b->alloc = b->comp_size;
+ if (!(b->data = malloc(b->comp_size))) { free(b); return NULL; }
+ if (b->comp_size != hread(fd->fp, b->data, b->comp_size)) {
+ free(b->data);
+ free(b);
+ return NULL;
+ }
+ }
+
+ if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ if (-1 == int32_decode(fd, (int32_t *)&b->crc32)) {
+ free(b);
+ return NULL;
+ }
+
+ crc = crc32(crc, b->data ? b->data : (uc *)"", b->alloc);
+ if (crc != b->crc32) {
+ fprintf(stderr, "Block CRC32 failure\n");
+ free(b->data);
+ free(b);
+ return NULL;
+ }
+ }
+
+ b->orig_method = b->method;
+ b->idx = 0;
+ b->byte = 0;
+ b->bit = 7; // MSB
+
+ return b;
+}
+
+
+/*
+ * Computes the size of a cram block, including the block
+ * header itself.
+ */
+uint32_t cram_block_size(cram_block *b) {
+ unsigned char dat[100], *cp = dat;;
+ uint32_t sz;
+
+ *cp++ = b->method;
+ *cp++ = b->content_type;
+ cp += itf8_put(cp, b->content_id);
+ cp += itf8_put(cp, b->comp_size);
+ cp += itf8_put(cp, b->uncomp_size);
+
+ sz = cp-dat + 4;
+ sz += b->method == RAW ? b->uncomp_size : b->comp_size;
+
+ return sz;
+}
+
+/*
+ * Writes a CRAM block.
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_write_block(cram_fd *fd, cram_block *b) {
+ assert(b->method != RAW || (b->comp_size == b->uncomp_size));
+
+ if (hputc(b->method, fd->fp) == EOF) return -1;
+ if (hputc(b->content_type, fd->fp) == EOF) return -1;
+ if (itf8_encode(fd, b->content_id) == -1) return -1;
+ if (itf8_encode(fd, b->comp_size) == -1) return -1;
+ if (itf8_encode(fd, b->uncomp_size) == -1) return -1;
+
+ if (b->method == RAW) {
+ if (b->uncomp_size != hwrite(fd->fp, b->data, b->uncomp_size))
+ return -1;
+ } else {
+ if (b->comp_size != hwrite(fd->fp, b->data, b->comp_size))
+ return -1;
+ }
+
+ if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ unsigned char dat[100], *cp = dat;;
+ uint32_t crc;
+
+ *cp++ = b->method;
+ *cp++ = b->content_type;
+ cp += itf8_put(cp, b->content_id);
+ cp += itf8_put(cp, b->comp_size);
+ cp += itf8_put(cp, b->uncomp_size);
+ crc = crc32(0L, dat, cp-dat);
+
+ if (b->method == RAW) {
+ b->crc32 = crc32(crc, b->data ? b->data : (uc*)"", b->uncomp_size);
+ } else {
+ b->crc32 = crc32(crc, b->data ? b->data : (uc*)"", b->comp_size);
+ }
+
+ if (-1 == int32_encode(fd, b->crc32))
+ return -1;
+ }
+
+ return 0;
+}
+
+/*
+ * Frees a CRAM block, deallocating internal data too.
+ */
+void cram_free_block(cram_block *b) {
+ if (!b)
+ return;
+ if (b->data)
+ free(b->data);
+ free(b);
+}
+
+/*
+ * Uncompresses a CRAM block, if compressed.
+ */
+int cram_uncompress_block(cram_block *b) {
+ char *uncomp;
+ size_t uncomp_size = 0;
+
+ if (b->uncomp_size == 0) {
+ // blank block
+ b->method = RAW;
+ return 0;
+ }
+
+ switch (b->method) {
+ case RAW:
+ return 0;
+
+ case GZIP:
+ uncomp = zlib_mem_inflate((char *)b->data, b->comp_size, &uncomp_size);
+ if (!uncomp)
+ return -1;
+ if ((int)uncomp_size != b->uncomp_size) {
+ free(uncomp);
+ return -1;
+ }
+ free(b->data);
+ b->data = (unsigned char *)uncomp;
+ b->alloc = uncomp_size;
+ b->method = RAW;
+ break;
+
+#ifdef HAVE_LIBBZ2
+ case BZIP2: {
+ unsigned int usize = b->uncomp_size;
+ if (!(uncomp = malloc(usize)))
+ return -1;
+ if (BZ_OK != BZ2_bzBuffToBuffDecompress(uncomp, &usize,
+ (char *)b->data, b->comp_size,
+ 0, 0)) {
+ free(uncomp);
+ return -1;
+ }
+ free(b->data);
+ b->data = (unsigned char *)uncomp;
+ b->alloc = usize;
+ b->method = RAW;
+ b->uncomp_size = usize; // Just incase it differs
+ break;
+ }
+#else
+ case BZIP2:
+ fprintf(stderr, "Bzip2 compression is not compiled into this "
+ "version.\nPlease rebuild and try again.\n");
+ return -1;
+#endif
+
+#ifdef HAVE_LIBLZMA
+ case LZMA:
+ uncomp = lzma_mem_inflate((char *)b->data, b->comp_size, &uncomp_size);
+ if (!uncomp)
+ return -1;
+ if ((int)uncomp_size != b->uncomp_size)
+ return -1;
+ free(b->data);
+ b->data = (unsigned char *)uncomp;
+ b->alloc = uncomp_size;
+ b->method = RAW;
+ break;
+#else
+ case LZMA:
+ fprintf(stderr, "Lzma compression is not compiled into this "
+ "version.\nPlease rebuild and try again.\n");
+ return -1;
+ break;
+#endif
+
+ case RANS: {
+ unsigned int usize = b->uncomp_size, usize2;
+ uncomp = (char *)rans_uncompress(b->data, b->comp_size, &usize2);
+ if (!uncomp || usize != usize2)
+ return -1;
+ free(b->data);
+ b->data = (unsigned char *)uncomp;
+ b->alloc = usize2;
+ b->method = RAW;
+ b->uncomp_size = usize2; // Just incase it differs
+ //fprintf(stderr, "Expanded %d to %d\n", b->comp_size, b->uncomp_size);
+ break;
+ }
+
+ default:
+ return -1;
+ }
+
+ return 0;
+}
+
+static char *cram_compress_by_method(char *in, size_t in_size,
+ size_t *out_size,
+ enum cram_block_method method,
+ int level, int strat) {
+ switch (method) {
+ case GZIP:
+ return zlib_mem_deflate(in, in_size, out_size, level, strat);
+
+ case BZIP2: {
+#ifdef HAVE_LIBBZ2
+ unsigned int comp_size = in_size*1.01 + 600;
+ char *comp = malloc(comp_size);
+ if (!comp)
+ return NULL;
+
+ if (BZ_OK != BZ2_bzBuffToBuffCompress(comp, &comp_size,
+ in, in_size,
+ level, 0, 30)) {
+ free(comp);
+ return NULL;
+ }
+ *out_size = comp_size;
+ return comp;
+#else
+ return NULL;
+#endif
+ }
+
+ case LZMA:
+#ifdef HAVE_LIBLZMA
+ return lzma_mem_deflate(in, in_size, out_size, level);
+#else
+ return NULL;
+#endif
+
+ case RANS0: {
+ unsigned int out_size_i;
+ unsigned char *cp;
+ cp = rans_compress((unsigned char *)in, in_size, &out_size_i, 0);
+ *out_size = out_size_i;
+ return (char *)cp;
+ }
+
+ case RANS1: {
+ unsigned int out_size_i;
+ unsigned char *cp;
+
+ cp = rans_compress((unsigned char *)in, in_size, &out_size_i, 1);
+ *out_size = out_size_i;
+ return (char *)cp;
+ }
+
+ case RAW:
+ break;
+
+ default:
+ return NULL;
+ }
+
+ return NULL;
+}
+
+
+/*
+ * Compresses a block using one of two different zlib strategies. If we only
+ * want one choice set strat2 to be -1.
+ *
+ * The logic here is that sometimes Z_RLE does a better job than Z_FILTERED
+ * or Z_DEFAULT_STRATEGY on quality data. If so, we'd rather use it as it is
+ * significantly faster.
+ *
+ * Method and level -1 implies defaults, as specified in cram_fd.
+ */
+int cram_compress_block(cram_fd *fd, cram_block *b, cram_metrics *metrics,
+ int method, int level) {
+
+ char *comp = NULL;
+ size_t comp_size = 0;
+ int strat;
+
+ if (b->method != RAW) {
+ // Maybe already compressed if s->block[0] was compressed and
+ // we have e.g. s->block[DS_BA] set to s->block[0] due to only
+ // one base type present and hence using E_HUFFMAN on block 0.
+ // A second explicit attempt to compress the same block then
+ // occurs.
+ return 0;
+ }
+
+ if (method == -1) {
+ method = 1<<GZIP;
+ if (fd->use_bz2)
+ method |= 1<<BZIP2;
+ if (fd->use_lzma)
+ method |= 1<<LZMA;
+ }
+
+ if (level == -1)
+ level = fd->level;
+
+ //fprintf(stderr, "IN: block %d, sz %d\n", b->content_id, b->uncomp_size);
+
+ if (method == RAW || level == 0 || b->uncomp_size == 0) {
+ b->method = RAW;
+ b->comp_size = b->uncomp_size;
+ //fprintf(stderr, "Skip block id %d\n", b->content_id);
+ return 0;
+ }
+
+ if (metrics) {
+ pthread_mutex_lock(&fd->metrics_lock);
+ if (metrics->trial > 0 || --metrics->next_trial <= 0) {
+ size_t sz_best = INT_MAX;
+ size_t sz_gz_rle = 0;
+ size_t sz_gz_def = 0;
+ size_t sz_rans0 = 0;
+ size_t sz_rans1 = 0;
+ size_t sz_bzip2 = 0;
+ size_t sz_lzma = 0;
+ int method_best = 0;
+ char *c_best = NULL, *c = NULL;
+
+ if (metrics->revised_method)
+ method = metrics->revised_method;
+ else
+ metrics->revised_method = method;
+
+ if (metrics->next_trial == 0) {
+ metrics->next_trial = TRIAL_SPAN;
+ metrics->trial = NTRIALS;
+ metrics->sz_gz_rle /= 2;
+ metrics->sz_gz_def /= 2;
+ metrics->sz_rans0 /= 2;
+ metrics->sz_rans1 /= 2;
+ metrics->sz_bzip2 /= 2;
+ metrics->sz_lzma /= 2;
+ }
+
+ pthread_mutex_unlock(&fd->metrics_lock);
+
+ if (method & (1<<GZIP_RLE)) {
+ c = cram_compress_by_method((char *)b->data, b->uncomp_size,
+ &sz_gz_rle, GZIP, 1, Z_RLE);
+ if (c && sz_best > sz_gz_rle) {
+ sz_best = sz_gz_rle;
+ method_best = GZIP_RLE;
+ if (c_best)
+ free(c_best);
+ c_best = c;
+ } else if (c) {
+ free(c);
+ } else {
+ sz_gz_rle = b->uncomp_size*2+1000;
+ }
+
+ //fprintf(stderr, "Block %d; %d->%d\n", b->content_id, b->uncomp_size, sz_gz_rle);
+ }
+
+ if (method & (1<<GZIP)) {
+ c = cram_compress_by_method((char *)b->data, b->uncomp_size,
+ &sz_gz_def, GZIP, level,
+ Z_FILTERED);
+ if (c && sz_best > sz_gz_def) {
+ sz_best = sz_gz_def;
+ method_best = GZIP;
+ if (c_best)
+ free(c_best);
+ c_best = c;
+ } else if (c) {
+ free(c);
+ } else {
+ sz_gz_def = b->uncomp_size*2+1000;
+ }
+
+ //fprintf(stderr, "Block %d; %d->%d\n", b->content_id, b->uncomp_size, sz_gz_def);
+ }
+
+ if (method & (1<<RANS0)) {
+ c = cram_compress_by_method((char *)b->data, b->uncomp_size,
+ &sz_rans0, RANS0, 0, 0);
+ if (c && sz_best > sz_rans0) {
+ sz_best = sz_rans0;
+ method_best = RANS0;
+ if (c_best)
+ free(c_best);
+ c_best = c;
+ } else if (c) {
+ free(c);
+ } else {
+ sz_rans0 = b->uncomp_size*2+1000;
+ }
+ }
+
+ if (method & (1<<RANS1)) {
+ c = cram_compress_by_method((char *)b->data, b->uncomp_size,
+ &sz_rans1, RANS1, 0, 0);
+ if (c && sz_best > sz_rans1) {
+ sz_best = sz_rans1;
+ method_best = RANS1;
+ if (c_best)
+ free(c_best);
+ c_best = c;
+ } else if (c) {
+ free(c);
+ } else {
+ sz_rans1 = b->uncomp_size*2+1000;
+ }
+ }
+
+ if (method & (1<<BZIP2)) {
+ c = cram_compress_by_method((char *)b->data, b->uncomp_size,
+ &sz_bzip2, BZIP2, level, 0);
+ if (c && sz_best > sz_bzip2) {
+ sz_best = sz_bzip2;
+ method_best = BZIP2;
+ if (c_best)
+ free(c_best);
+ c_best = c;
+ } else if (c) {
+ free(c);
+ } else {
+ sz_bzip2 = b->uncomp_size*2+1000;
+ }
+ }
+
+ if (method & (1<<LZMA)) {
+ c = cram_compress_by_method((char *)b->data, b->uncomp_size,
+ &sz_lzma, LZMA, level, 0);
+ if (c && sz_best > sz_lzma) {
+ sz_best = sz_lzma;
+ method_best = LZMA;
+ if (c_best)
+ free(c_best);
+ c_best = c;
+ } else if (c) {
+ free(c);
+ } else {
+ sz_lzma = b->uncomp_size*2+1000;
+ }
+ }
+
+ //fprintf(stderr, "sz_best = %d\n", sz_best);
+
+ free(b->data);
+ b->data = (unsigned char *)c_best;
+ //printf("method_best = %s\n", cram_block_method2str(method_best));
+ b->method = method_best == GZIP_RLE ? GZIP : method_best;
+ b->comp_size = sz_best;
+
+ pthread_mutex_lock(&fd->metrics_lock);
+ metrics->sz_gz_rle += sz_gz_rle;
+ metrics->sz_gz_def += sz_gz_def;
+ metrics->sz_rans0 += sz_rans0;
+ metrics->sz_rans1 += sz_rans1;
+ metrics->sz_bzip2 += sz_bzip2;
+ metrics->sz_lzma += sz_lzma;
+ if (--metrics->trial == 0) {
+ int best_method = RAW;
+ int best_sz = INT_MAX;
+
+ // Scale methods by cost
+ if (fd->level <= 3) {
+ metrics->sz_rans1 *= 1.02;
+ metrics->sz_gz_def *= 1.04;
+ metrics->sz_bzip2 *= 1.08;
+ metrics->sz_lzma *= 1.10;
+ } else if (fd->level <= 6) {
+ metrics->sz_rans1 *= 1.01;
+ metrics->sz_gz_def *= 1.02;
+ metrics->sz_bzip2 *= 1.03;
+ metrics->sz_lzma *= 1.05;
+ }
+
+ if (method & (1<<GZIP_RLE) && best_sz > metrics->sz_gz_rle)
+ best_sz = metrics->sz_gz_rle, best_method = GZIP_RLE;
+
+ if (method & (1<<GZIP) && best_sz > metrics->sz_gz_def)
+ best_sz = metrics->sz_gz_def, best_method = GZIP;
+
+ if (method & (1<<RANS0) && best_sz > metrics->sz_rans0)
+ best_sz = metrics->sz_rans0, best_method = RANS0;
+
+ if (method & (1<<RANS1) && best_sz > metrics->sz_rans1)
+ best_sz = metrics->sz_rans1, best_method = RANS1;
+
+ if (method & (1<<BZIP2) && best_sz > metrics->sz_bzip2)
+ best_sz = metrics->sz_bzip2, best_method = BZIP2;
+
+ if (method & (1<<LZMA) && best_sz > metrics->sz_lzma)
+ best_sz = metrics->sz_lzma, best_method = LZMA;
+
+ if (best_method == GZIP_RLE) {
+ metrics->method = GZIP;
+ metrics->strat = Z_RLE;
+ } else {
+ metrics->method = best_method;
+ metrics->strat = Z_FILTERED;
+ }
+
+ // If we see at least MAXFAIL trials in a row for a specific
+ // compression method with more than MAXDELTA aggregate
+ // size then we drop this from the list of methods used
+ // for this block type.
+#define MAXDELTA 0.20
+#define MAXFAILS 4
+ if (best_method == GZIP_RLE) {
+ metrics->gz_rle_cnt = 0;
+ metrics->gz_rle_extra = 0;
+ } else if (best_sz < metrics->sz_gz_rle) {
+ double r = (double)metrics->sz_gz_rle / best_sz - 1;
+ if (++metrics->gz_rle_cnt >= MAXFAILS &&
+ (metrics->gz_rle_extra += r) >= MAXDELTA)
+ method &= ~(1<<GZIP_RLE);
+ }
+
+ if (best_method == GZIP) {
+ metrics->gz_def_cnt = 0;
+ metrics->gz_def_extra = 0;
+ } else if (best_sz < metrics->sz_gz_def) {
+ double r = (double)metrics->sz_gz_def / best_sz - 1;
+ if (++metrics->gz_def_cnt >= MAXFAILS &&
+ (metrics->gz_def_extra += r) >= MAXDELTA)
+ method &= ~(1<<GZIP);
+ }
+
+ if (best_method == RANS0) {
+ metrics->rans0_cnt = 0;
+ metrics->rans0_extra = 0;
+ } else if (best_sz < metrics->sz_rans0) {
+ double r = (double)metrics->sz_rans0 / best_sz - 1;
+ if (++metrics->rans0_cnt >= MAXFAILS &&
+ (metrics->rans0_extra += r) >= MAXDELTA)
+ method &= ~(1<<RANS0);
+ }
+
+ if (best_method == RANS1) {
+ metrics->rans1_cnt = 0;
+ metrics->rans1_extra = 0;
+ } else if (best_sz < metrics->sz_rans1) {
+ double r = (double)metrics->sz_rans1 / best_sz - 1;
+ if (++metrics->rans1_cnt >= MAXFAILS &&
+ (metrics->rans1_extra += r) >= MAXDELTA)
+ method &= ~(1<<RANS1);
+ }
+
+ if (best_method == BZIP2) {
+ metrics->bzip2_cnt = 0;
+ metrics->bzip2_extra = 0;
+ } else if (best_sz < metrics->sz_bzip2) {
+ double r = (double)metrics->sz_bzip2 / best_sz - 1;
+ if (++metrics->bzip2_cnt >= MAXFAILS &&
+ (metrics->bzip2_extra += r) >= MAXDELTA)
+ method &= ~(1<<BZIP2);
+ }
+
+ if (best_method == LZMA) {
+ metrics->lzma_cnt = 0;
+ metrics->lzma_extra = 0;
+ } else if (best_sz < metrics->sz_lzma) {
+ double r = (double)metrics->sz_lzma / best_sz - 1;
+ if (++metrics->lzma_cnt >= MAXFAILS &&
+ (metrics->lzma_extra += r) >= MAXDELTA)
+ method &= ~(1<<LZMA);
+ }
+
+ //if (method != metrics->revised_method)
+ // fprintf(stderr, "%d: method from %x to %x\n",
+ // b->content_id, metrics->revised_method, method);
+ metrics->revised_method = method;
+ }
+ pthread_mutex_unlock(&fd->metrics_lock);
+ } else {
+ strat = metrics->strat;
+ method = metrics->method;
+
+ pthread_mutex_unlock(&fd->metrics_lock);
+ comp = cram_compress_by_method((char *)b->data, b->uncomp_size,
+ &comp_size, method,
+ level, strat);
+ if (!comp)
+ return -1;
+ free(b->data);
+ b->data = (unsigned char *)comp;
+ b->comp_size = comp_size;
+ b->method = method;
+ }
+
+ } else {
+ // no cached metrics, so just do zlib?
+ comp = cram_compress_by_method((char *)b->data, b->uncomp_size,
+ &comp_size, GZIP, level, Z_FILTERED);
+ if (!comp) {
+ fprintf(stderr, "Compression failed!\n");
+ return -1;
+ }
+ free(b->data);
+ b->data = (unsigned char *)comp;
+ b->comp_size = comp_size;
+ b->method = GZIP;
+ }
+
+ if (fd->verbose)
+ fprintf(stderr, "Compressed block ID %d from %d to %d by method %s\n",
+ b->content_id, b->uncomp_size, b->comp_size,
+ cram_block_method2str(b->method));
+
+ if (b->method == RANS1)
+ b->method = RANS0; // Spec just has RANS (not 0/1) with auto-sensing
+
+ return 0;
+}
+
+cram_metrics *cram_new_metrics(void) {
+ cram_metrics *m = calloc(1, sizeof(*m));
+ if (!m)
+ return NULL;
+ m->trial = NTRIALS-1;
+ m->next_trial = TRIAL_SPAN;
+ m->method = RAW;
+ m->strat = 0;
+ m->revised_method = 0;
+
+ return m;
+}
+
+char *cram_block_method2str(enum cram_block_method m) {
+ switch(m) {
+ case RAW: return "RAW";
+ case GZIP: return "GZIP";
+ case BZIP2: return "BZIP2";
+ case LZMA: return "LZMA";
+ case RANS0: return "RANS0";
+ case RANS1: return "RANS1";
+ case GZIP_RLE: return "GZIP_RLE";
+ case ERROR: break;
+ }
+ return "?";
+}
+
+char *cram_content_type2str(enum cram_content_type t) {
+ switch (t) {
+ case FILE_HEADER: return "FILE_HEADER";
+ case COMPRESSION_HEADER: return "COMPRESSION_HEADER";
+ case MAPPED_SLICE: return "MAPPED_SLICE";
+ case UNMAPPED_SLICE: return "UNMAPPED_SLICE";
+ case EXTERNAL: return "EXTERNAL";
+ case CORE: return "CORE";
+ case CT_ERROR: break;
+ }
+ return "?";
+}
+
+/*
+ * Extra error checking on fclose to really ensure data is written.
+ * Care needs to be taken to handle pipes vs real files.
+ *
+ * Returns 0 on success
+ * -1 on failure.
+ */
+int paranoid_fclose(FILE *fp) {
+ if (-1 == fflush(fp) && errno != EBADF) {
+ fclose(fp);
+ return -1;
+ }
+
+ errno = 0;
+ if (-1 == fsync(fileno(fp))) {
+ if (errno != EINVAL) { // eg pipe
+ fclose(fp);
+ return -1;
+ }
+ }
+ return fclose(fp);
+}
+
+/* ----------------------------------------------------------------------
+ * Reference sequence handling
+ *
+ * These revolve around the refs_t structure, which may potentially be
+ * shared between multiple cram_fd.
+ *
+ * We start with refs_create() to allocate an empty refs_t and then
+ * populate it with @SQ line data using refs_from_header(). This is done on
+ * cram_open(). Also at start up we can call cram_load_reference() which
+ * is used with "scramble -r foo.fa". This replaces the fd->refs with the
+ * new one specified. In either case refs2id() is then called which
+ * maps ref_entry names to @SQ ids (refs_t->ref_id[]).
+ *
+ * Later, possibly within a thread, we will want to know the actual ref
+ * seq itself, obtained by calling cram_get_ref(). This may use the
+ * UR: or M5: fields or the filename specified in the original
+ * cram_load_reference() call.
+ *
+ * Given the potential for multi-threaded reference usage, we have
+ * reference counting (sorry for the confusing double use of "ref") to
+ * track the number of callers interested in any specific reference.
+ */
+
+/*
+ * Frees/unmaps a reference sequence and associated file handles.
+ */
+static void ref_entry_free_seq(ref_entry *e) {
+ if (e->mf)
+ mfclose(e->mf);
+ if (e->seq && !e->mf)
+ free(e->seq);
+
+ e->seq = NULL;
+ e->mf = NULL;
+}
+
+void refs_free(refs_t *r) {
+ RP("refs_free()\n");
+
+ if (--r->count > 0)
+ return;
+
+ if (!r)
+ return;
+
+ if (r->pool)
+ string_pool_destroy(r->pool);
+
+ if (r->h_meta) {
+ khint_t k;
+
+ for (k = kh_begin(r->h_meta); k != kh_end(r->h_meta); k++) {
+ ref_entry *e;
+
+ if (!kh_exist(r->h_meta, k))
+ continue;
+ if (!(e = kh_val(r->h_meta, k)))
+ continue;
+ ref_entry_free_seq(e);
+ free(e);
+ }
+
+ kh_destroy(refs, r->h_meta);
+ }
+
+ if (r->ref_id)
+ free(r->ref_id);
+
+ if (r->fp)
+ bgzf_close(r->fp);
+
+ pthread_mutex_destroy(&r->lock);
+
+ free(r);
+}
+
+static refs_t *refs_create(void) {
+ refs_t *r = calloc(1, sizeof(*r));
+
+ RP("refs_create()\n");
+
+ if (!r)
+ return NULL;
+
+ if (!(r->pool = string_pool_create(8192)))
+ goto err;
+
+ r->ref_id = NULL; // see refs2id() to populate.
+ r->count = 1;
+ r->last = NULL;
+ r->last_id = -1;
+
+ if (!(r->h_meta = kh_init(refs)))
+ goto err;
+
+ pthread_mutex_init(&r->lock, NULL);
+
+ return r;
+
+ err:
+ refs_free(r);
+ return NULL;
+}
+
+/*
+ * Opens a reference fasta file as a BGZF stream, allowing for
+ * compressed files. It automatically builds a .fai file if
+ * required and if compressed a .gzi bgzf index too.
+ *
+ * Returns a BGZF handle on success;
+ * NULL on failure.
+ */
+static BGZF *bgzf_open_ref(char *fn, char *mode, int is_md5) {
+ BGZF *fp;
+
+ if (!is_md5) {
+ char fai_file[PATH_MAX];
+
+ snprintf(fai_file, PATH_MAX, "%s.fai", fn);
+ if (access(fai_file, R_OK) != 0)
+ if (fai_build(fn) != 0)
+ return NULL;
+ }
+
+ if (!(fp = bgzf_open(fn, mode))) {
+ perror(fn);
+ return NULL;
+ }
+
+ if (fp->is_compressed == 1 && bgzf_index_load(fp, fn, ".gzi") < 0) {
+ fprintf(stderr, "Unable to load .gzi index '%s.gzi'\n", fn);
+ bgzf_close(fp);
+ return NULL;
+ }
+
+ return fp;
+}
+
+/*
+ * Loads a FAI file for a reference.fasta.
+ * "is_err" indicates whether failure to load is worthy of emitting an
+ * error message. In some cases (eg with embedded references) we
+ * speculatively load, just incase, and silently ignore errors.
+ *
+ * Returns the refs_t struct on success (maybe newly allocated);
+ * NULL on failure
+ */
+static refs_t *refs_load_fai(refs_t *r_orig, char *fn, int is_err) {
+ struct stat sb;
+ FILE *fp = NULL;
+ char fai_fn[PATH_MAX];
+ char line[8192];
+ refs_t *r = r_orig;
+ size_t fn_l = strlen(fn);
+ int id = 0, id_alloc = 0;
+
+ RP("refs_load_fai %s\n", fn);
+
+ if (!r)
+ if (!(r = refs_create()))
+ goto err;
+
+ /* Open reference, for later use */
+ if (stat(fn, &sb) != 0) {
+ if (is_err)
+ perror(fn);
+ goto err;
+ }
+
+ if (r->fp)
+ if (bgzf_close(r->fp) != 0)
+ goto err;
+ r->fp = NULL;
+
+ if (!(r->fn = string_dup(r->pool, fn)))
+ goto err;
+
+ if (fn_l > 4 && strcmp(&fn[fn_l-4], ".fai") == 0)
+ r->fn[fn_l-4] = 0;
+
+ if (!(r->fp = bgzf_open_ref(r->fn, "r", 0)))
+ goto err;
+
+ /* Parse .fai file and load meta-data */
+ sprintf(fai_fn, "%.*s.fai", PATH_MAX-5, r->fn);
+
+ if (stat(fai_fn, &sb) != 0) {
+ if (is_err)
+ perror(fai_fn);
+ goto err;
+ }
+ if (!(fp = fopen(fai_fn, "r"))) {
+ if (is_err)
+ perror(fai_fn);
+ goto err;
+ }
+ while (fgets(line, 8192, fp) != NULL) {
+ ref_entry *e = malloc(sizeof(*e));
+ char *cp;
+ int n;
+ khint_t k;
+
+ if (!e)
+ return NULL;
+
+ // id
+ for (cp = line; *cp && !isspace(*cp); cp++)
+ ;
+ *cp++ = 0;
+ e->name = string_dup(r->pool, line);
+
+ // length
+ while (*cp && isspace(*cp))
+ cp++;
+ e->length = strtoll(cp, &cp, 10);
+
+ // offset
+ while (*cp && isspace(*cp))
+ cp++;
+ e->offset = strtoll(cp, &cp, 10);
+
+ // bases per line
+ while (*cp && isspace(*cp))
+ cp++;
+ e->bases_per_line = strtol(cp, &cp, 10);
+
+ // line length
+ while (*cp && isspace(*cp))
+ cp++;
+ e->line_length = strtol(cp, &cp, 10);
+
+ // filename
+ e->fn = r->fn;
+
+ e->count = 0;
+ e->seq = NULL;
+ e->mf = NULL;
+ e->is_md5 = 0;
+
+ k = kh_put(refs, r->h_meta, e->name, &n);
+ if (-1 == n) {
+ free(e);
+ return NULL;
+ }
+
+ if (n) {
+ kh_val(r->h_meta, k) = e;
+ } else {
+ ref_entry *re = kh_val(r->h_meta, k);
+ if (re && (re->count != 0 || re->length != 0)) {
+ /* Keep old */
+ free(e);
+ } else {
+ /* Replace old */
+ if (re)
+ free(re);
+ kh_val(r->h_meta, k) = e;
+ }
+ }
+
+ if (id >= id_alloc) {
+ int x;
+
+ id_alloc = id_alloc ?id_alloc*2 : 16;
+ r->ref_id = realloc(r->ref_id, id_alloc * sizeof(*r->ref_id));
+
+ for (x = id; x < id_alloc; x++)
+ r->ref_id[x] = NULL;
+ }
+ r->ref_id[id] = e;
+ r->nref = ++id;
+ }
+
+ return r;
+
+ err:
+ if (fp)
+ fclose(fp);
+
+ if (!r_orig)
+ refs_free(r);
+
+ return NULL;
+}
+
+/*
+ * Verifies that the CRAM @SQ lines and .fai files match.
+ */
+static void sanitise_SQ_lines(cram_fd *fd) {
+ int i;
+
+ if (!fd->header)
+ return;
+
+ if (!fd->refs || !fd->refs->h_meta)
+ return;
+
+ for (i = 0; i < fd->header->nref; i++) {
+ char *name = fd->header->ref[i].name;
+ khint_t k = kh_get(refs, fd->refs->h_meta, name);
+ ref_entry *r;
+
+ // We may have @SQ lines which have no known .fai, but do not
+ // in themselves pose a problem because they are unused in the file.
+ if (k == kh_end(fd->refs->h_meta))
+ continue;
+
+ if (!(r = (ref_entry *)kh_val(fd->refs->h_meta, k)))
+ continue;
+
+ if (r->length && r->length != fd->header->ref[i].len) {
+ assert(strcmp(r->name, fd->header->ref[i].name) == 0);
+
+ // Should we also check MD5sums here to ensure the correct
+ // reference was given?
+ fprintf(stderr, "WARNING: Header @SQ length mismatch for "
+ "ref %s, %d vs %d\n",
+ r->name, fd->header->ref[i].len, (int)r->length);
+
+ // Fixing the parsed @SQ header will make MD:Z: strings work
+ // and also stop it producing N for the sequence.
+ fd->header->ref[i].len = r->length;
+ }
+ }
+}
+
+/*
+ * Indexes references by the order they appear in a BAM file. This may not
+ * necessarily be the same order they appear in the fasta reference file.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int refs2id(refs_t *r, SAM_hdr *h) {
+ int i;
+
+ if (r->ref_id)
+ free(r->ref_id);
+ if (r->last)
+ r->last = NULL;
+
+ r->ref_id = calloc(h->nref, sizeof(*r->ref_id));
+ if (!r->ref_id)
+ return -1;
+
+ r->nref = h->nref;
+ for (i = 0; i < h->nref; i++) {
+ khint_t k = kh_get(refs, r->h_meta, h->ref[i].name);
+ if (k != kh_end(r->h_meta)) {
+ r->ref_id[i] = kh_val(r->h_meta, k);
+ } else {
+ fprintf(stderr, "Unable to find ref name '%s'\n",
+ h->ref[i].name);
+ }
+ }
+
+ return 0;
+}
+
+/*
+ * Generates refs_t entries based on @SQ lines in the header.
+ * Returns 0 on success
+ * -1 on failure
+ */
+static int refs_from_header(refs_t *r, cram_fd *fd, SAM_hdr *h) {
+ int i, j;
+
+ if (!r)
+ return -1;
+
+ if (!h || h->nref == 0)
+ return 0;
+
+ //fprintf(stderr, "refs_from_header for %p mode %c\n", fd, fd->mode);
+
+ /* Existing refs are fine, as long as they're compatible with the hdr. */
+ if (!(r->ref_id = realloc(r->ref_id, (r->nref + h->nref) * sizeof(*r->ref_id))))
+ return -1;
+
+ /* Copy info from h->ref[i] over to r */
+ for (i = 0, j = r->nref; i < h->nref; i++) {
+ SAM_hdr_type *ty;
+ SAM_hdr_tag *tag;
+ khint_t k;
+ int n;
+
+ k = kh_get(refs, r->h_meta, h->ref[i].name);
+ if (k != kh_end(r->h_meta))
+ // Ref already known about
+ continue;
+
+ if (!(r->ref_id[j] = calloc(1, sizeof(ref_entry))))
+ return -1;
+
+ if (!h->ref[i].name)
+ return -1;
+
+ r->ref_id[j]->name = string_dup(r->pool, h->ref[i].name);
+ r->ref_id[j]->length = 0; // marker for not yet loaded
+
+ /* Initialise likely filename if known */
+ if ((ty = sam_hdr_find(h, "SQ", "SN", h->ref[i].name))) {
+ if ((tag = sam_hdr_find_key(h, ty, "M5", NULL))) {
+ r->ref_id[j]->fn = string_dup(r->pool, tag->str+3);
+ //fprintf(stderr, "Tagging @SQ %s / %s\n", r->ref_id[h]->name, r->ref_id[h]->fn);
+ }
+ }
+
+ k = kh_put(refs, r->h_meta, r->ref_id[j]->name, &n);
+ if (n <= 0) // already exists or error
+ return -1;
+ kh_val(r->h_meta, k) = r->ref_id[j];
+
+ j++;
+ }
+ r->nref = j;
+
+ return 0;
+}
+
+/*
+ * Attaches a header to a cram_fd.
+ *
+ * This should be used when creating a new cram_fd for writing where
+ * we have an SAM_hdr already constructed (eg from a file we've read
+ * in).
+ */
+int cram_set_header(cram_fd *fd, SAM_hdr *hdr) {
+ if (fd->header)
+ sam_hdr_free(fd->header);
+ fd->header = hdr;
+ return refs_from_header(fd->refs, fd, hdr);
+}
+
+/*
+ * Converts a directory and a filename into an expanded path, replacing %s
+ * in directory with the filename and %[0-9]+s with portions of the filename
+ * Any remaining parts of filename are added to the end with /%s.
+ */
+void expand_cache_path(char *path, char *dir, char *fn) {
+ char *cp;
+
+ while ((cp = strchr(dir, '%'))) {
+ strncpy(path, dir, cp-dir);
+ path += cp-dir;
+
+ if (*++cp == 's') {
+ strcpy(path, fn);
+ path += strlen(fn);
+ fn += strlen(fn);
+ cp++;
+ } else if (*cp >= '0' && *cp <= '9') {
+ char *endp;
+ long l;
+
+ l = strtol(cp, &endp, 10);
+ l = MIN(l, strlen(fn));
+ if (*endp == 's') {
+ strncpy(path, fn, l);
+ path += l;
+ fn += l;
+ *path = 0;
+ cp = endp+1;
+ } else {
+ *path++ = '%';
+ *path++ = *cp++;
+ }
+ } else {
+ *path++ = '%';
+ *path++ = *cp++;
+ }
+ dir = cp;
+ }
+ strcpy(path, dir);
+ path += strlen(dir);
+ if (*fn && path[-1] != '/')
+ *path++ = '/';
+ strcpy(path, fn);
+}
+
+/*
+ * Make the directory containing path and any prefix directories.
+ */
+void mkdir_prefix(char *path, int mode) {
+ char *cp = strrchr(path, '/');
+ if (!cp)
+ return;
+
+ *cp = 0;
+ if (is_directory(path)) {
+ *cp = '/';
+ return;
+ }
+
+ if (mkdir(path, mode) == 0) {
+ chmod(path, mode);
+ *cp = '/';
+ return;
+ }
+
+ mkdir_prefix(path, mode);
+ mkdir(path, mode);
+ chmod(path, mode);
+ *cp = '/';
+}
+
+/*
+ * Return the cache directory to use, based on the first of these
+ * environment variables to be set to a non-empty value.
+ */
+static const char *get_cache_basedir(const char **extra) {
+ char *base;
+
+ *extra = "";
+
+ base = getenv("XDG_CACHE_HOME");
+ if (base && *base) return base;
+
+ base = getenv("HOME");
+ if (base && *base) { *extra = "/.cache"; return base; }
+
+ base = getenv("TMPDIR");
+ if (base && *base) return base;
+
+ base = getenv("TEMP");
+ if (base && *base) return base;
+
+ return "/tmp";
+}
+
+/*
+ * Return an integer representation of pthread_self().
+ */
+static unsigned get_int_threadid() {
+ pthread_t pt = pthread_self();
+ unsigned char *s = (unsigned char *) &pt;
+ size_t i;
+ unsigned h = 0;
+ for (i = 0; i < sizeof(pthread_t); i++)
+ h = (h << 5) - h + s[i];
+ return h;
+}
+
+/*
+ * Queries the M5 string from the header and attempts to populate the
+ * reference from this using the REF_PATH environment.
+ *
+ * Returns 0 on sucess
+ * -1 on failure
+ */
+static int cram_populate_ref(cram_fd *fd, int id, ref_entry *r) {
+ char *ref_path = getenv("REF_PATH");
+ SAM_hdr_type *ty;
+ SAM_hdr_tag *tag;
+ char path[PATH_MAX], path_tmp[PATH_MAX];
+ char cache[PATH_MAX], cache_root[PATH_MAX];
+ char *local_cache = getenv("REF_CACHE");
+ mFILE *mf;
+ int local_path = 0;
+
+ if (fd->verbose)
+ fprintf(stderr, "cram_populate_ref on fd %p, id %d\n", fd, id);
+
+ cache_root[0] = '\0';
+
+ if (!ref_path || *ref_path == '\0') {
+ /*
+ * If we have no ref path, we use the EBI server.
+ * However to avoid spamming it we require a local ref cache too.
+ */
+ ref_path = "http://www.ebi.ac.uk:80/ena/cram/md5/%s";
+ if (!local_cache || *local_cache == '\0') {
+ const char *extra;
+ const char *base = get_cache_basedir(&extra);
+ snprintf(cache_root, PATH_MAX, "%s%s/hts-ref", base, extra);
+ snprintf(cache,PATH_MAX, "%s%s/hts-ref/%%2s/%%2s/%%s", base, extra);
+ local_cache = cache;
+ if (fd->verbose)
+ fprintf(stderr, "Populating local cache: %s\n", local_cache);
+ }
+ }
+
+ if (!r->name)
+ return -1;
+
+ if (!(ty = sam_hdr_find(fd->header, "SQ", "SN", r->name)))
+ return -1;
+
+ if (!(tag = sam_hdr_find_key(fd->header, ty, "M5", NULL)))
+ goto no_M5;
+
+ if (fd->verbose)
+ fprintf(stderr, "Querying ref %s\n", tag->str+3);
+
+ /* Use cache if available */
+ if (local_cache && *local_cache) {
+ expand_cache_path(path, local_cache, tag->str+3);
+ local_path = 1;
+ }
+
+#ifndef HAVE_MMAP
+ char *path2;
+ /* Search local files in REF_PATH; we can open them and return as above */
+ if (!local_path && (path2 = find_path(tag->str+3, ref_path))) {
+ strncpy(path, path2, PATH_MAX);
+ free(path2);
+ if (is_file(path)) // incase it's too long
+ local_path = 1;
+ }
+#endif
+
+ /* Found via REF_CACHE or local REF_PATH file */
+ if (local_path) {
+ struct stat sb;
+ BGZF *fp;
+
+ if (0 == stat(path, &sb) && (fp = bgzf_open(path, "r"))) {
+ r->length = sb.st_size;
+ r->offset = r->line_length = r->bases_per_line = 0;
+
+ r->fn = string_dup(fd->refs->pool, path);
+
+ if (fd->refs->fp)
+ if (bgzf_close(fd->refs->fp) != 0)
+ return -1;
+ fd->refs->fp = fp;
+ fd->refs->fn = r->fn;
+ r->is_md5 = 1;
+
+ // Fall back to cram_get_ref() where it'll do the actual
+ // reading of the file.
+ return 0;
+ }
+ }
+
+
+ /* Otherwise search full REF_PATH; slower as loads entire file */
+ if ((mf = open_path_mfile(tag->str+3, ref_path, NULL))) {
+ size_t sz;
+ r->seq = mfsteal(mf, &sz);
+ if (r->seq) {
+ r->mf = NULL;
+ } else {
+ // keep mf around as we couldn't detach
+ r->seq = mf->data;
+ r->mf = mf;
+ }
+ r->length = sz;
+ r->is_md5 = 1;
+ } else {
+ refs_t *refs;
+ char *fn;
+
+ no_M5:
+ /* Failed to find in search path or M5 cache, see if @SQ UR: tag? */
+ if (!(tag = sam_hdr_find_key(fd->header, ty, "UR", NULL)))
+ return -1;
+
+ fn = (strncmp(tag->str+3, "file:", 5) == 0)
+ ? tag->str+8
+ : tag->str+3;
+
+ if (fd->refs->fp) {
+ if (bgzf_close(fd->refs->fp) != 0)
+ return -1;
+ fd->refs->fp = NULL;
+ }
+ if (!(refs = refs_load_fai(fd->refs, fn, 0)))
+ return -1;
+ sanitise_SQ_lines(fd);
+
+ fd->refs = refs;
+ if (fd->refs->fp) {
+ if (bgzf_close(fd->refs->fp) != 0)
+ return -1;
+ fd->refs->fp = NULL;
+ }
+
+ if (!fd->refs->fn)
+ return -1;
+
+ if (-1 == refs2id(fd->refs, fd->header))
+ return -1;
+ if (!fd->refs->ref_id || !fd->refs->ref_id[id])
+ return -1;
+
+ // Local copy already, so fall back to cram_get_ref().
+ return 0;
+ }
+
+ /* Populate the local disk cache if required */
+ if (local_cache && *local_cache) {
+ int pid = (int) getpid();
+ unsigned thrid = get_int_threadid();
+ FILE *fp;
+
+ if (*cache_root && !is_directory(cache_root) && hts_verbose >= 1)
+ fprintf(stderr,
+"Creating reference cache directory %s\n"
+"This may become large; see the samtools(1) manual page REF_CACHE discussion\n",
+ cache_root);
+
+ expand_cache_path(path, local_cache, tag->str+3);
+ if (fd->verbose)
+ fprintf(stderr, "Writing cache file '%s'\n", path);
+ mkdir_prefix(path, 01777);
+
+ do {
+ // Attempt to further uniquify the temporary filename
+ unsigned t = ((unsigned) time(NULL)) ^ ((unsigned) clock());
+ thrid++; // Ensure filename changes even if time/clock haven't
+
+ sprintf(path_tmp, "%s.tmp_%d_%u_%u", path, pid, thrid, t);
+ fp = fopen(path_tmp, "wx");
+ } while (fp == NULL && errno == EEXIST);
+ if (!fp) {
+ perror(path_tmp);
+
+ // Not fatal - we have the data already so keep going.
+ return 0;
+ }
+
+ // Check md5sum
+ hts_md5_context *md5;
+ char unsigned md5_buf1[16];
+ char md5_buf2[33];
+
+ if (!(md5 = hts_md5_init())) {
+ unlink(path_tmp);
+ fclose(fp);
+ return -1;
+ }
+ hts_md5_update(md5, r->seq, r->length);
+ hts_md5_final(md5_buf1, md5);
+ hts_md5_destroy(md5);
+ hts_md5_hex(md5_buf2, md5_buf1);
+
+ if (strncmp(tag->str+3, md5_buf2, 32) != 0) {
+ fprintf(stderr, "[E::%s] mismatching md5sum for downloaded reference.\n", __func__);
+ unlink(path_tmp);
+ fclose(fp);
+ return -1;
+ }
+
+ if (r->length != fwrite(r->seq, 1, r->length, fp)) {
+ perror(path);
+ }
+ if (-1 == paranoid_fclose(fp)) {
+ unlink(path_tmp);
+ } else {
+ if (0 == chmod(path_tmp, 0444))
+ rename(path_tmp, path);
+ else
+ unlink(path_tmp);
+ }
+ }
+
+ return 0;
+}
+
+static void cram_ref_incr_locked(refs_t *r, int id) {
+ RP("%d INC REF %d, %d %p\n", gettid(), id, (int)(id>=0?r->ref_id[id]->count+1:-999), id>=0?r->ref_id[id]->seq:(char *)1);
+
+ if (id < 0 || !r->ref_id[id]->seq)
+ return;
+
+ if (r->last_id == id)
+ r->last_id = -1;
+
+ ++r->ref_id[id]->count;
+}
+
+void cram_ref_incr(refs_t *r, int id) {
+ pthread_mutex_lock(&r->lock);
+ cram_ref_incr_locked(r, id);
+ pthread_mutex_unlock(&r->lock);
+}
+
+static void cram_ref_decr_locked(refs_t *r, int id) {
+ RP("%d DEC REF %d, %d %p\n", gettid(), id, (int)(id>=0?r->ref_id[id]->count-1:-999), id>=0?r->ref_id[id]->seq:(char *)1);
+
+ if (id < 0 || !r->ref_id[id]->seq) {
+ assert(r->ref_id[id]->count >= 0);
+ return;
+ }
+
+ if (--r->ref_id[id]->count <= 0) {
+ assert(r->ref_id[id]->count == 0);
+ if (r->last_id >= 0) {
+ if (r->ref_id[r->last_id]->count <= 0 &&
+ r->ref_id[r->last_id]->seq) {
+ RP("%d FREE REF %d (%p)\n", gettid(),
+ r->last_id, r->ref_id[r->last_id]->seq);
+ ref_entry_free_seq(r->ref_id[r->last_id]);
+ r->ref_id[r->last_id]->length = 0;
+ }
+ }
+ r->last_id = id;
+ }
+}
+
+void cram_ref_decr(refs_t *r, int id) {
+ pthread_mutex_lock(&r->lock);
+ cram_ref_decr_locked(r, id);
+ pthread_mutex_unlock(&r->lock);
+}
+
+/*
+ * Used by cram_ref_load and cram_ref_get. The file handle will have
+ * already been opened, so we can catch it. The ref_entry *e informs us
+ * of whether this is a multi-line fasta file or a raw MD5 style file.
+ * Either way we create a single contiguous sequence.
+ *
+ * Returns all or part of a reference sequence on success (malloced);
+ * NULL on failure.
+ */
+static char *load_ref_portion(BGZF *fp, ref_entry *e, int start, int end) {
+ off_t offset, len;
+ char *seq;
+
+ if (end < start)
+ end = start;
+
+ /*
+ * Compute locations in file. This is trivial for the MD5 files, but
+ * is still necessary for the fasta variants.
+ */
+ offset = e->line_length
+ ? e->offset + (start-1)/e->bases_per_line * e->line_length +
+ (start-1) % e->bases_per_line
+ : start-1;
+
+ len = (e->line_length
+ ? e->offset + (end-1)/e->bases_per_line * e->line_length +
+ (end-1) % e->bases_per_line
+ : end-1) - offset + 1;
+
+ if (bgzf_useek(fp, offset, SEEK_SET) < 0) {
+ perror("bgzf_useek() on reference file");
+ return NULL;
+ }
+
+ if (len == 0 || !(seq = malloc(len))) {
+ return NULL;
+ }
+
+ if (len != bgzf_read(fp, seq, len)) {
+ perror("bgzf_read() on reference file");
+ free(seq);
+ return NULL;
+ }
+
+ /* Strip white-space if required. */
+ if (len != end-start+1) {
+ int i, j;
+ char *cp = seq;
+ char *cp_to;
+
+ for (i = j = 0; i < len; i++) {
+ if (cp[i] >= '!' && cp[i] <= '~')
+ cp[j++] = toupper(cp[i]);
+ }
+ cp_to = cp+j;
+
+ if (cp_to - seq != end-start+1) {
+ fprintf(stderr, "Malformed reference file?\n");
+ free(seq);
+ return NULL;
+ }
+ } else {
+ int i;
+ for (i = 0; i < len; i++) {
+ seq[i] = toupper(seq[i]);
+ }
+ }
+
+ return seq;
+}
+
+/*
+ * Load the entire reference 'id'.
+ * This also increments the reference count by 1.
+ *
+ * Returns ref_entry on success;
+ * NULL on failure
+ */
+ref_entry *cram_ref_load(refs_t *r, int id, int is_md5) {
+ ref_entry *e = r->ref_id[id];
+ int start = 1, end = e->length;
+ char *seq;
+
+ if (e->seq) {
+ return e;
+ }
+
+ assert(e->count == 0);
+
+ if (r->last) {
+#ifdef REF_DEBUG
+ int idx = 0;
+ for (idx = 0; idx < r->nref; idx++)
+ if (r->last == r->ref_id[idx])
+ break;
+ RP("%d cram_ref_load DECR %d\n", gettid(), idx);
+#endif
+ assert(r->last->count > 0);
+ if (--r->last->count <= 0) {
+ RP("%d FREE REF %d (%p)\n", gettid(), id, r->ref_id[id]->seq);
+ if (r->last->seq)
+ ref_entry_free_seq(r->last);
+ }
+ }
+
+ /* Open file if it's not already the current open reference */
+ if (strcmp(r->fn, e->fn) || r->fp == NULL) {
+ if (r->fp)
+ if (bgzf_close(r->fp) != 0)
+ return NULL;
+ r->fn = e->fn;
+ if (!(r->fp = bgzf_open_ref(r->fn, "r", is_md5)))
+ return NULL;
+ }
+
+ RP("%d Loading ref %d (%d..%d)\n", gettid(), id, start, end);
+
+ if (!(seq = load_ref_portion(r->fp, e, start, end))) {
+ return NULL;
+ }
+
+ RP("%d Loaded ref %d (%d..%d) = %p\n", gettid(), id, start, end, seq);
+
+ RP("%d INC REF %d, %d\n", gettid(), id, (int)(e->count+1));
+ e->seq = seq;
+ e->mf = NULL;
+ e->count++;
+
+ /*
+ * Also keep track of last used ref so incr/decr loops on the same
+ * sequence don't cause load/free loops.
+ */
+ RP("%d cram_ref_load INCR %d => %d\n", gettid(), id, e->count+1);
+ r->last = e;
+ e->count++;
+
+ return e;
+}
+
+/*
+ * Returns a portion of a reference sequence from start to end inclusive.
+ * The returned pointer is owned by either the cram_file fd or by the
+ * internal refs_t structure and should not be freed by the caller.
+ *
+ * The difference is whether or not this refs_t is in use by just the one
+ * cram_fd or by multiples, or whether we have multiple threads accessing
+ * references. In either case fd->shared will be true and we start using
+ * reference counting to track the number of users of a specific reference
+ * sequence.
+ *
+ * Otherwise the ref seq returned is allocated as part of cram_fd itself
+ * and will be freed up on the next call to cram_get_ref or cram_close.
+ *
+ * To return the entire reference sequence, specify start as 1 and end
+ * as 0.
+ *
+ * To cease using a reference, call cram_ref_decr().
+ *
+ * Returns reference on success,
+ * NULL on failure
+ */
+char *cram_get_ref(cram_fd *fd, int id, int start, int end) {
+ ref_entry *r;
+ char *seq;
+ int ostart = start;
+
+ if (id == -1)
+ return NULL;
+
+ /* FIXME: axiomatic query of r->seq being true?
+ * Or shortcut for unsorted data where we load once and never free?
+ */
+
+ //fd->shared_ref = 1; // hard code for now to simplify things
+
+ pthread_mutex_lock(&fd->ref_lock);
+
+ RP("%d cram_get_ref on fd %p, id %d, range %d..%d\n", gettid(), fd, id, start, end);
+
+ /*
+ * Unsorted data implies we want to fetch an entire reference at a time.
+ * We just deal with this at the moment by claiming we're sharing
+ * references instead, which has the same requirement.
+ */
+ if (fd->unsorted)
+ fd->shared_ref = 1;
+
+
+ /* Sanity checking: does this ID exist? */
+ if (id >= fd->refs->nref) {
+ fprintf(stderr, "No reference found for id %d\n", id);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return NULL;
+ }
+
+ if (!fd->refs || !fd->refs->ref_id[id]) {
+ fprintf(stderr, "No reference found for id %d\n", id);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return NULL;
+ }
+
+ if (!(r = fd->refs->ref_id[id])) {
+ fprintf(stderr, "No reference found for id %d\n", id);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return NULL;
+ }
+
+
+ /*
+ * It has an entry, but may not have been populated yet.
+ * Any manually loaded .fai files have their lengths known.
+ * A ref entry computed from @SQ lines (M5 or UR field) will have
+ * r->length == 0 unless it's been loaded once and verified that we have
+ * an on-disk filename for it.
+ *
+ * 19 Sep 2013: Moved the lock here as the cram_populate_ref code calls
+ * open_path_mfile and libcurl, which isn't multi-thread safe unless I
+ * rewrite my code to have one curl handle per thread.
+ */
+ pthread_mutex_lock(&fd->refs->lock);
+ if (r->length == 0) {
+ if (cram_populate_ref(fd, id, r) == -1) {
+ fprintf(stderr, "Failed to populate reference for id %d\n", id);
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return NULL;
+ }
+ r = fd->refs->ref_id[id];
+ if (fd->unsorted)
+ cram_ref_incr_locked(fd->refs, id);
+ }
+
+
+ /*
+ * We now know that we the filename containing the reference, so check
+ * for limits. If it's over half the reference we'll load all of it in
+ * memory as this will speed up subsequent calls.
+ */
+ if (end < 1)
+ end = r->length;
+ if (end >= r->length)
+ end = r->length;
+ assert(start >= 1);
+
+ if (end - start >= 0.5*r->length || fd->shared_ref) {
+ start = 1;
+ end = r->length;
+ }
+
+ /*
+ * Maybe we have it cached already? If so use it.
+ *
+ * Alternatively if we don't have the sequence but we're sharing
+ * references and/or are asking for the entire length of it, then
+ * load the full reference into the refs structure and return
+ * a pointer to that one instead.
+ */
+ if (fd->shared_ref || r->seq || (start == 1 && end == r->length)) {
+ char *cp;
+
+ if (id >= 0) {
+ if (r->seq) {
+ cram_ref_incr_locked(fd->refs, id);
+ } else {
+ ref_entry *e;
+ if (!(e = cram_ref_load(fd->refs, id, r->is_md5))) {
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return NULL;
+ }
+
+ /* unsorted data implies cache ref indefinitely, to avoid
+ * continually loading and unloading.
+ */
+ if (fd->unsorted)
+ cram_ref_incr_locked(fd->refs, id);
+ }
+
+ fd->ref = NULL; /* We never access it directly */
+ fd->ref_start = 1;
+ fd->ref_end = r->length;
+ fd->ref_id = id;
+
+ cp = fd->refs->ref_id[id]->seq + ostart-1;
+ } else {
+ fd->ref = NULL;
+ cp = NULL;
+ }
+
+ RP("%d cram_get_ref returning for id %d, count %d\n", gettid(), id, (int)r->count);
+
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return cp;
+ }
+
+ /*
+ * Otherwise we're not sharing, we don't have a copy of it already and
+ * we're only asking for a small portion of it.
+ *
+ * In this case load up just that segment ourselves, freeing any old
+ * small segments in the process.
+ */
+
+ /* Unmapped ref ID */
+ if (id < 0) {
+ if (fd->ref_free) {
+ free(fd->ref_free);
+ fd->ref_free = NULL;
+ }
+ fd->ref = NULL;
+ fd->ref_id = id;
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return NULL;
+ }
+
+ /* Open file if it's not already the current open reference */
+ if (strcmp(fd->refs->fn, r->fn) || fd->refs->fp == NULL) {
+ if (fd->refs->fp)
+ if (bgzf_close(fd->refs->fp) != 0)
+ return NULL;
+ fd->refs->fn = r->fn;
+ if (!(fd->refs->fp = bgzf_open_ref(fd->refs->fn, "r", r->is_md5))) {
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return NULL;
+ }
+ }
+
+ if (!(fd->ref = load_ref_portion(fd->refs->fp, r, start, end))) {
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+ return NULL;
+ }
+
+ if (fd->ref_free)
+ free(fd->ref_free);
+
+ fd->ref_id = id;
+ fd->ref_start = start;
+ fd->ref_end = end;
+ fd->ref_free = fd->ref;
+ seq = fd->ref;
+
+ pthread_mutex_unlock(&fd->refs->lock);
+ pthread_mutex_unlock(&fd->ref_lock);
+
+ return seq + ostart - start;
+}
+
+/*
+ * If fd has been opened for reading, it may be permitted to specify 'fn'
+ * as NULL and let the code auto-detect the reference by parsing the
+ * SAM header @SQ lines.
+ */
+int cram_load_reference(cram_fd *fd, char *fn) {
+ int ret = 0;
+
+ if (fn) {
+ fd->refs = refs_load_fai(fd->refs, fn,
+ !(fd->embed_ref && fd->mode == 'r'));
+ fn = fd->refs ? fd->refs->fn : NULL;
+ if (!fn)
+ ret = -1;
+ sanitise_SQ_lines(fd);
+ }
+ fd->ref_fn = fn;
+
+ if ((!fd->refs || (fd->refs->nref == 0 && !fn)) && fd->header) {
+ if (fd->refs)
+ refs_free(fd->refs);
+ if (!(fd->refs = refs_create()))
+ return -1;
+ if (-1 == refs_from_header(fd->refs, fd, fd->header))
+ return -1;
+ }
+
+ if (fd->header)
+ if (-1 == refs2id(fd->refs, fd->header))
+ return -1;
+
+ return ret;
+}
+
+/* ----------------------------------------------------------------------
+ * Containers
+ */
+
+/*
+ * Creates a new container, specifying the maximum number of slices
+ * and records permitted.
+ *
+ * Returns cram_container ptr on success
+ * NULL on failure
+ */
+cram_container *cram_new_container(int nrec, int nslice) {
+ cram_container *c = calloc(1, sizeof(*c));
+ enum cram_DS_ID id;
+
+ if (!c)
+ return NULL;
+
+ c->curr_ref = -2;
+
+ c->max_c_rec = nrec * nslice;
+ c->curr_c_rec = 0;
+
+ c->max_rec = nrec;
+ c->record_counter = 0;
+ c->num_bases = 0;
+
+ c->max_slice = nslice;
+ c->curr_slice = 0;
+
+ c->pos_sorted = 1;
+ c->max_apos = 0;
+ c->multi_seq = 0;
+
+ c->bams = NULL;
+
+ if (!(c->slices = (cram_slice **)calloc(nslice, sizeof(cram_slice *))))
+ goto err;
+ c->slice = NULL;
+
+ if (!(c->comp_hdr = cram_new_compression_header()))
+ goto err;
+ c->comp_hdr_block = NULL;
+
+ for (id = DS_RN; id < DS_TN; id++)
+ if (!(c->stats[id] = cram_stats_create())) goto err;
+
+ //c->aux_B_stats = cram_stats_create();
+
+ if (!(c->tags_used = kh_init(s_i2i)))
+ goto err;
+ c->refs_used = 0;
+
+ return c;
+
+ err:
+ if (c) {
+ if (c->slices)
+ free(c->slices);
+ free(c);
+ }
+ return NULL;
+}
+
+void cram_free_container(cram_container *c) {
+ enum cram_DS_ID id;
+ int i;
+
+ if (!c)
+ return;
+
+ if (c->refs_used)
+ free(c->refs_used);
+
+ if (c->landmark)
+ free(c->landmark);
+
+ if (c->comp_hdr)
+ cram_free_compression_header(c->comp_hdr);
+
+ if (c->comp_hdr_block)
+ cram_free_block(c->comp_hdr_block);
+
+ if (c->slices) {
+ for (i = 0; i < c->max_slice; i++)
+ if (c->slices[i])
+ cram_free_slice(c->slices[i]);
+ free(c->slices);
+ }
+
+ for (id = DS_RN; id < DS_TN; id++)
+ if (c->stats[id]) cram_stats_free(c->stats[id]);
+
+ //if (c->aux_B_stats) cram_stats_free(c->aux_B_stats);
+
+ if (c->tags_used) kh_destroy(s_i2i, c->tags_used);
+
+ free(c);
+}
+
+/*
+ * Reads a container header.
+ *
+ * Returns cram_container on success
+ * NULL on failure or no container left (fd->err == 0).
+ */
+cram_container *cram_read_container(cram_fd *fd) {
+ cram_container c2, *c;
+ int i, s;
+ size_t rd = 0;
+ uint32_t crc = 0;
+
+ fd->err = 0;
+ fd->eof = 0;
+
+ memset(&c2, 0, sizeof(c2));
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ if ((s = itf8_decode_crc(fd, &c2.length, &crc)) == -1) {
+ fd->eof = fd->empty_container ? 1 : 2;
+ return NULL;
+ } else {
+ rd+=s;
+ }
+ } else {
+ uint32_t len;
+ if ((s = int32_decode(fd, &c2.length)) == -1) {
+ if (CRAM_MAJOR_VERS(fd->version) == 2 &&
+ CRAM_MINOR_VERS(fd->version) == 0)
+ fd->eof = 1; // EOF blocks arrived in v2.1
+ else
+ fd->eof = fd->empty_container ? 1 : 2;
+ return NULL;
+ } else {
+ rd+=s;
+ }
+ len = le_int4(c2.length);
+ crc = crc32(0L, (unsigned char *)&len, 4);
+ }
+ if ((s = itf8_decode_crc(fd, &c2.ref_seq_id, &crc)) == -1) return NULL; else rd+=s;
+ if ((s = itf8_decode_crc(fd, &c2.ref_seq_start, &crc))== -1) return NULL; else rd+=s;
+ if ((s = itf8_decode_crc(fd, &c2.ref_seq_span, &crc)) == -1) return NULL; else rd+=s;
+ if ((s = itf8_decode_crc(fd, &c2.num_records, &crc)) == -1) return NULL; else rd+=s;
+
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ c2.record_counter = 0;
+ c2.num_bases = 0;
+ } else {
+ if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ if ((s = ltf8_decode_crc(fd, &c2.record_counter, &crc)) == -1)
+ return NULL;
+ else
+ rd += s;
+ } else {
+ int32_t i32;
+ if ((s = itf8_decode_crc(fd, &i32, &crc)) == -1)
+ return NULL;
+ else
+ rd += s;
+ c2.record_counter = i32;
+ }
+
+ if ((s = ltf8_decode_crc(fd, &c2.num_bases, &crc))== -1)
+ return NULL;
+ else
+ rd += s;
+ }
+ if ((s = itf8_decode_crc(fd, &c2.num_blocks, &crc)) == -1) return NULL; else rd+=s;
+ if ((s = itf8_decode_crc(fd, &c2.num_landmarks, &crc))== -1) return NULL; else rd+=s;
+
+ if (!(c = calloc(1, sizeof(*c))))
+ return NULL;
+
+ *c = c2;
+
+ if (!(c->landmark = malloc(c->num_landmarks * sizeof(int32_t))) &&
+ c->num_landmarks) {
+ fd->err = errno;
+ cram_free_container(c);
+ return NULL;
+ }
+ for (i = 0; i < c->num_landmarks; i++) {
+ if ((s = itf8_decode_crc(fd, &c->landmark[i], &crc)) == -1) {
+ cram_free_container(c);
+ return NULL;
+ } else {
+ rd += s;
+ }
+ }
+
+ if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ if (-1 == int32_decode(fd, (int32_t *)&c->crc32))
+ return NULL;
+ else
+ rd+=4;
+
+ if (crc != c->crc32) {
+ fprintf(stderr, "Container header CRC32 failure\n");
+ cram_free_container(c);
+ return NULL;
+ }
+ }
+
+ c->offset = rd;
+ c->slices = NULL;
+ c->curr_slice = 0;
+ c->max_slice = c->num_landmarks;
+ c->slice_rec = 0;
+ c->curr_rec = 0;
+ c->max_rec = 0;
+
+ if (c->ref_seq_id == -2) {
+ c->multi_seq = 1;
+ fd->multi_seq = 1;
+ }
+
+ fd->empty_container =
+ (c->num_records == 0 &&
+ c->ref_seq_id == -1 &&
+ c->ref_seq_start == 0x454f46 /* EOF */) ? 1 : 0;
+
+ return c;
+}
+
+
+/* MAXIMUM storage size needed for the container. */
+int cram_container_size(cram_container *c) {
+ return 55 + 5*c->num_landmarks;
+}
+
+
+/*
+ * Stores the container structure in dat and returns *size as the
+ * number of bytes written to dat[]. The input size of dat is also
+ * held in *size and should be initialised to cram_container_size(c).
+ *
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_store_container(cram_fd *fd, cram_container *c, char *dat, int *size)
+{
+ char *cp = dat;
+ int i;
+
+ // Check the input buffer is large enough according to our stated
+ // requirements. (NOTE: it may actually take less.)
+ if (cram_container_size(c) > *size)
+ return -1;
+
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ cp += itf8_put(cp, c->length);
+ } else {
+ *(int32_t *)cp = le_int4(c->length);
+ cp += 4;
+ }
+ if (c->multi_seq) {
+ cp += itf8_put(cp, -2);
+ cp += itf8_put(cp, 0);
+ cp += itf8_put(cp, 0);
+ } else {
+ cp += itf8_put(cp, c->ref_seq_id);
+ cp += itf8_put(cp, c->ref_seq_start);
+ cp += itf8_put(cp, c->ref_seq_span);
+ }
+ cp += itf8_put(cp, c->num_records);
+ if (CRAM_MAJOR_VERS(fd->version) == 2) {
+ cp += itf8_put(cp, c->record_counter);
+ cp += ltf8_put(cp, c->num_bases);
+ } else if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ cp += ltf8_put(cp, c->record_counter);
+ cp += ltf8_put(cp, c->num_bases);
+ }
+
+ cp += itf8_put(cp, c->num_blocks);
+ cp += itf8_put(cp, c->num_landmarks);
+ for (i = 0; i < c->num_landmarks; i++)
+ cp += itf8_put(cp, c->landmark[i]);
+
+ if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ c->crc32 = crc32(0L, (uc *)dat, cp-dat);
+ cp[0] = c->crc32 & 0xff;
+ cp[1] = (c->crc32 >> 8) & 0xff;
+ cp[2] = (c->crc32 >> 16) & 0xff;
+ cp[3] = (c->crc32 >> 24) & 0xff;
+ cp += 4;
+ }
+
+ *size = cp-dat; // actual used size
+
+ return 0;
+}
+
+
+/*
+ * Writes a container structure.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_write_container(cram_fd *fd, cram_container *c) {
+ char buf_a[1024], *buf = buf_a, *cp;
+ int i;
+
+ if (55 + c->num_landmarks * 5 >= 1024)
+ buf = malloc(55 + c->num_landmarks * 5);
+ cp = buf;
+
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ cp += itf8_put(cp, c->length);
+ } else {
+ *(int32_t *)cp = le_int4(c->length);
+ cp += 4;
+ }
+ if (c->multi_seq) {
+ cp += itf8_put(cp, -2);
+ cp += itf8_put(cp, 0);
+ cp += itf8_put(cp, 0);
+ } else {
+ cp += itf8_put(cp, c->ref_seq_id);
+ cp += itf8_put(cp, c->ref_seq_start);
+ cp += itf8_put(cp, c->ref_seq_span);
+ }
+ cp += itf8_put(cp, c->num_records);
+ if (CRAM_MAJOR_VERS(fd->version) == 2) {
+ cp += itf8_put(cp, c->record_counter);
+ cp += ltf8_put(cp, c->num_bases);
+ } else if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ cp += ltf8_put(cp, c->record_counter);
+ cp += ltf8_put(cp, c->num_bases);
+ }
+
+ cp += itf8_put(cp, c->num_blocks);
+ cp += itf8_put(cp, c->num_landmarks);
+ for (i = 0; i < c->num_landmarks; i++)
+ cp += itf8_put(cp, c->landmark[i]);
+
+ if (CRAM_MAJOR_VERS(fd->version) >= 3) {
+ c->crc32 = crc32(0L, (uc *)buf, cp-buf);
+ cp[0] = c->crc32 & 0xff;
+ cp[1] = (c->crc32 >> 8) & 0xff;
+ cp[2] = (c->crc32 >> 16) & 0xff;
+ cp[3] = (c->crc32 >> 24) & 0xff;
+ cp += 4;
+ }
+
+ if (cp-buf != hwrite(fd->fp, buf, cp-buf)) {
+ if (buf != buf_a)
+ free(buf);
+ return -1;
+ }
+
+ if (buf != buf_a)
+ free(buf);
+
+ return 0;
+}
+
+// common component shared by cram_flush_container{,_mt}
+static int cram_flush_container2(cram_fd *fd, cram_container *c) {
+ int i, j;
+
+ if (c->curr_slice > 0 && !c->slices)
+ return -1;
+
+ //fprintf(stderr, "Writing container %d, sum %u\n", c->record_counter, sum);
+
+ /* Write the container struct itself */
+ if (0 != cram_write_container(fd, c))
+ return -1;
+
+ /* And the compression header */
+ if (0 != cram_write_block(fd, c->comp_hdr_block))
+ return -1;
+
+ /* Followed by the slice blocks */
+ for (i = 0; i < c->curr_slice; i++) {
+ cram_slice *s = c->slices[i];
+
+ if (0 != cram_write_block(fd, s->hdr_block))
+ return -1;
+
+ for (j = 0; j < s->hdr->num_blocks; j++) {
+ if (0 != cram_write_block(fd, s->block[j]))
+ return -1;
+ }
+ }
+
+ return hflush(fd->fp) == 0 ? 0 : -1;
+}
+
+/*
+ * Flushes a completely or partially full container to disk, writing
+ * container structure, header and blocks. This also calls the encoder
+ * functions.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_flush_container(cram_fd *fd, cram_container *c) {
+ /* Encode the container blocks and generate compression header */
+ if (0 != cram_encode_container(fd, c))
+ return -1;
+
+ return cram_flush_container2(fd, c);
+}
+
+typedef struct {
+ cram_fd *fd;
+ cram_container *c;
+} cram_job;
+
+void *cram_flush_thread(void *arg) {
+ cram_job *j = (cram_job *)arg;
+
+ /* Encode the container blocks and generate compression header */
+ if (0 != cram_encode_container(j->fd, j->c)) {
+ fprintf(stderr, "cram_encode_container failed\n");
+ return NULL;
+ }
+
+ return arg;
+}
+
+static int cram_flush_result(cram_fd *fd) {
+ int i, ret = 0;
+ t_pool_result *r;
+
+ while ((r = t_pool_next_result(fd->rqueue))) {
+ cram_job *j = (cram_job *)r->data;
+ cram_container *c;
+
+ if (!j) {
+ t_pool_delete_result(r, 0);
+ return -1;
+ }
+
+ fd = j->fd;
+ c = j->c;
+
+ if (0 != cram_flush_container2(fd, c))
+ return -1;
+
+ /* Free the container */
+ for (i = 0; i < c->max_slice; i++) {
+ cram_free_slice(c->slices[i]);
+ c->slices[i] = NULL;
+ }
+
+ c->slice = NULL;
+ c->curr_slice = 0;
+
+ cram_free_container(c);
+
+ ret |= hflush(fd->fp) == 0 ? 0 : -1;
+
+ t_pool_delete_result(r, 1);
+ }
+
+ return ret;
+}
+
+int cram_flush_container_mt(cram_fd *fd, cram_container *c) {
+ cram_job *j;
+
+ if (!fd->pool)
+ return cram_flush_container(fd, c);
+
+ if (!(j = malloc(sizeof(*j))))
+ return -1;
+ j->fd = fd;
+ j->c = c;
+
+ t_pool_dispatch(fd->pool, fd->rqueue, cram_flush_thread, j);
+
+ return cram_flush_result(fd);
+}
+
+/* ----------------------------------------------------------------------
+ * Compression headers; the first part of the container
+ */
+
+/*
+ * Creates a new blank container compression header
+ *
+ * Returns header ptr on success
+ * NULL on failure
+ */
+cram_block_compression_hdr *cram_new_compression_header(void) {
+ cram_block_compression_hdr *hdr = calloc(1, sizeof(*hdr));
+ if (!hdr)
+ return NULL;
+
+ if (!(hdr->TD_blk = cram_new_block(CORE, 0))) {
+ free(hdr);
+ return NULL;
+ }
+
+ if (!(hdr->TD_hash = kh_init(m_s2i))) {
+ cram_free_block(hdr->TD_blk);
+ free(hdr);
+ return NULL;
+ }
+
+ if (!(hdr->TD_keys = string_pool_create(8192))) {
+ kh_destroy(m_s2i, hdr->TD_hash);
+ cram_free_block(hdr->TD_blk);
+ free(hdr);
+ return NULL;
+ }
+
+ return hdr;
+}
+
+void cram_free_compression_header(cram_block_compression_hdr *hdr) {
+ int i;
+
+ if (hdr->landmark)
+ free(hdr->landmark);
+
+ if (hdr->preservation_map)
+ kh_destroy(map, hdr->preservation_map);
+
+ for (i = 0; i < CRAM_MAP_HASH; i++) {
+ cram_map *m, *m2;
+ for (m = hdr->rec_encoding_map[i]; m; m = m2) {
+ m2 = m->next;
+ if (m->codec)
+ m->codec->free(m->codec);
+ free(m);
+ }
+ }
+
+ for (i = 0; i < CRAM_MAP_HASH; i++) {
+ cram_map *m, *m2;
+ for (m = hdr->tag_encoding_map[i]; m; m = m2) {
+ m2 = m->next;
+ if (m->codec)
+ m->codec->free(m->codec);
+ free(m);
+ }
+ }
+
+ for (i = 0; i < DS_END; i++) {
+ if (hdr->codecs[i])
+ hdr->codecs[i]->free(hdr->codecs[i]);
+ }
+
+ if (hdr->TL)
+ free(hdr->TL);
+ if (hdr->TD_blk)
+ cram_free_block(hdr->TD_blk);
+ if (hdr->TD_hash)
+ kh_destroy(m_s2i, hdr->TD_hash);
+ if (hdr->TD_keys)
+ string_pool_destroy(hdr->TD_keys);
+
+ free(hdr);
+}
+
+
+/* ----------------------------------------------------------------------
+ * Slices and slice headers
+ */
+
+void cram_free_slice_header(cram_block_slice_hdr *hdr) {
+ if (!hdr)
+ return;
+
+ if (hdr->block_content_ids)
+ free(hdr->block_content_ids);
+
+ free(hdr);
+
+ return;
+}
+
+void cram_free_slice(cram_slice *s) {
+ if (!s)
+ return;
+
+ if (s->hdr_block)
+ cram_free_block(s->hdr_block);
+
+ if (s->block) {
+ int i;
+
+ if (s->hdr) {
+ for (i = 0; i < s->hdr->num_blocks; i++) {
+ cram_free_block(s->block[i]);
+ }
+ }
+ free(s->block);
+ }
+
+ if (s->block_by_id)
+ free(s->block_by_id);
+
+ if (s->hdr)
+ cram_free_slice_header(s->hdr);
+
+ if (s->seqs_blk)
+ cram_free_block(s->seqs_blk);
+
+ if (s->qual_blk)
+ cram_free_block(s->qual_blk);
+
+ if (s->name_blk)
+ cram_free_block(s->name_blk);
+
+ if (s->aux_blk)
+ cram_free_block(s->aux_blk);
+
+ if (s->aux_OQ_blk)
+ cram_free_block(s->aux_OQ_blk);
+
+ if (s->aux_BQ_blk)
+ cram_free_block(s->aux_BQ_blk);
+
+ if (s->aux_FZ_blk)
+ cram_free_block(s->aux_FZ_blk);
+
+ if (s->aux_oq_blk)
+ cram_free_block(s->aux_oq_blk);
+
+ if (s->aux_os_blk)
+ cram_free_block(s->aux_os_blk);
+
+ if (s->aux_oz_blk)
+ cram_free_block(s->aux_oz_blk);
+
+ if (s->base_blk)
+ cram_free_block(s->base_blk);
+
+ if (s->soft_blk)
+ cram_free_block(s->soft_blk);
+
+ if (s->cigar)
+ free(s->cigar);
+
+ if (s->crecs)
+ free(s->crecs);
+
+ if (s->features)
+ free(s->features);
+
+ if (s->TN)
+ free(s->TN);
+
+ if (s->pair_keys)
+ string_pool_destroy(s->pair_keys);
+
+ if (s->pair[0])
+ kh_destroy(m_s2i, s->pair[0]);
+ if (s->pair[1])
+ kh_destroy(m_s2i, s->pair[1]);
+
+ free(s);
+}
+
+/*
+ * Creates a new empty slice in memory, for subsequent writing to
+ * disk.
+ *
+ * Returns cram_slice ptr on success
+ * NULL on failure
+ */
+cram_slice *cram_new_slice(enum cram_content_type type, int nrecs) {
+ cram_slice *s = calloc(1, sizeof(*s));
+ if (!s)
+ return NULL;
+
+ if (!(s->hdr = (cram_block_slice_hdr *)calloc(1, sizeof(*s->hdr))))
+ goto err;
+ s->hdr->content_type = type;
+
+ s->hdr_block = NULL;
+ s->block = NULL;
+ s->block_by_id = NULL;
+ s->last_apos = 0;
+ if (!(s->crecs = malloc(nrecs * sizeof(cram_record)))) goto err;
+ s->cigar = NULL;
+ s->cigar_alloc = 0;
+ s->ncigar = 0;
+
+ if (!(s->seqs_blk = cram_new_block(EXTERNAL, 0))) goto err;
+ if (!(s->qual_blk = cram_new_block(EXTERNAL, DS_QS))) goto err;
+ if (!(s->name_blk = cram_new_block(EXTERNAL, DS_RN))) goto err;
+ if (!(s->aux_blk = cram_new_block(EXTERNAL, DS_aux))) goto err;
+ if (!(s->base_blk = cram_new_block(EXTERNAL, DS_IN))) goto err;
+ if (!(s->soft_blk = cram_new_block(EXTERNAL, DS_SC))) goto err;
+
+ s->features = NULL;
+ s->nfeatures = s->afeatures = 0;
+
+#ifndef TN_external
+ s->TN = NULL;
+ s->nTN = s->aTN = 0;
+#endif
+
+ // Volatile keys as we do realloc in dstring
+ if (!(s->pair_keys = string_pool_create(8192))) goto err;
+ if (!(s->pair[0] = kh_init(m_s2i))) goto err;
+ if (!(s->pair[1] = kh_init(m_s2i))) goto err;
+
+#ifdef BA_external
+ s->BA_len = 0;
+#endif
+
+ return s;
+
+ err:
+ if (s)
+ cram_free_slice(s);
+
+ return NULL;
+}
+
+/*
+ * Loads an entire slice.
+ * FIXME: In 1.0 the native unit of slices within CRAM is broken
+ * as slices contain references to objects in other slices.
+ * To work around this while keeping the slice oriented outer loop
+ * we read all slices and stitch them together into a fake large
+ * slice instead.
+ *
+ * Returns cram_slice ptr on success
+ * NULL on failure
+ */
+cram_slice *cram_read_slice(cram_fd *fd) {
+ cram_block *b = cram_read_block(fd);
+ cram_slice *s = calloc(1, sizeof(*s));
+ int i, n, max_id, min_id;
+
+ if (!b || !s)
+ goto err;
+
+ s->hdr_block = b;
+ switch (b->content_type) {
+ case MAPPED_SLICE:
+ case UNMAPPED_SLICE:
+ if (!(s->hdr = cram_decode_slice_header(fd, b)))
+ goto err;
+ break;
+
+ default:
+ fprintf(stderr, "Unexpected block of type %s\n",
+ cram_content_type2str(b->content_type));
+ goto err;
+ }
+
+ if (s->hdr->num_blocks < 1) {
+ fprintf(stderr, "Slice does not include any data blocks.\n");
+ goto err;
+ }
+
+ s->block = calloc(n = s->hdr->num_blocks, sizeof(*s->block));
+ if (!s->block)
+ goto err;
+
+ for (max_id = i = 0, min_id = INT_MAX; i < n; i++) {
+ if (!(s->block[i] = cram_read_block(fd)))
+ goto err;
+
+ if (s->block[i]->content_type == EXTERNAL) {
+ if (max_id < s->block[i]->content_id)
+ max_id = s->block[i]->content_id;
+ if (min_id > s->block[i]->content_id)
+ min_id = s->block[i]->content_id;
+ }
+ }
+ if (min_id >= 0 && max_id < 1024) {
+ if (!(s->block_by_id = calloc(1024, sizeof(s->block[0]))))
+ goto err;
+
+ for (i = 0; i < n; i++) {
+ if (s->block[i]->content_type != EXTERNAL)
+ continue;
+ s->block_by_id[s->block[i]->content_id] = s->block[i];
+ }
+ }
+
+ /* Initialise encoding/decoding tables */
+ s->cigar = NULL;
+ s->cigar_alloc = 0;
+ s->ncigar = 0;
+
+ if (!(s->seqs_blk = cram_new_block(EXTERNAL, 0))) goto err;
+ if (!(s->qual_blk = cram_new_block(EXTERNAL, DS_QS))) goto err;
+ if (!(s->name_blk = cram_new_block(EXTERNAL, DS_RN))) goto err;
+ if (!(s->aux_blk = cram_new_block(EXTERNAL, DS_aux))) goto err;
+ if (!(s->base_blk = cram_new_block(EXTERNAL, DS_IN))) goto err;
+ if (!(s->soft_blk = cram_new_block(EXTERNAL, DS_SC))) goto err;
+
+ s->crecs = NULL;
+
+ s->last_apos = s->hdr->ref_seq_start;
+
+ return s;
+
+ err:
+ if (b)
+ cram_free_block(b);
+ if (s) {
+ s->hdr_block = NULL;
+ cram_free_slice(s);
+ }
+ return NULL;
+}
+
+
+/* ----------------------------------------------------------------------
+ * CRAM file definition (header)
+ */
+
+/*
+ * Reads a CRAM file definition structure.
+ * Returns file_def ptr on success
+ * NULL on failure
+ */
+cram_file_def *cram_read_file_def(cram_fd *fd) {
+ cram_file_def *def = malloc(sizeof(*def));
+ if (!def)
+ return NULL;
+
+ if (26 != hread(fd->fp, &def->magic[0], 26)) {
+ free(def);
+ return NULL;
+ }
+
+ if (memcmp(def->magic, "CRAM", 4) != 0) {
+ free(def);
+ return NULL;
+ }
+
+ if (def->major_version > 3) {
+ fprintf(stderr, "CRAM version number mismatch\n"
+ "Expected 1.x, 2.x or 3.x, got %d.%d\n",
+ def->major_version, def->minor_version);
+ free(def);
+ return NULL;
+ }
+
+ fd->first_container += 26;
+ fd->last_slice = 0;
+
+ return def;
+}
+
+/*
+ * Writes a cram_file_def structure to cram_fd.
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_write_file_def(cram_fd *fd, cram_file_def *def) {
+ return (hwrite(fd->fp, &def->magic[0], 26) == 26) ? 0 : -1;
+}
+
+void cram_free_file_def(cram_file_def *def) {
+ if (def) free(def);
+}
+
+/* ----------------------------------------------------------------------
+ * SAM header I/O
+ */
+
+
+/*
+ * Reads the SAM header from the first CRAM data block.
+ * Also performs minimal parsing to extract read-group
+ * and sample information.
+
+ * Returns SAM hdr ptr on success
+ * NULL on failure
+ */
+SAM_hdr *cram_read_SAM_hdr(cram_fd *fd) {
+ int32_t header_len;
+ char *header;
+ SAM_hdr *hdr;
+
+ /* 1.1 onwards stores the header in the first block of a container */
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ /* Length */
+ if (-1 == int32_decode(fd, &header_len))
+ return NULL;
+
+ /* Alloc and read */
+ if (header_len < 0 || NULL == (header = malloc((size_t) header_len+1)))
+ return NULL;
+
+ if (header_len != hread(fd->fp, header, header_len))
+ return NULL;
+ header[header_len] = '\0';
+
+ fd->first_container += 4 + header_len;
+ } else {
+ cram_container *c = cram_read_container(fd);
+ cram_block *b;
+ int i, len;
+
+ if (!c)
+ return NULL;
+
+ if (c->num_blocks < 1) {
+ cram_free_container(c);
+ return NULL;
+ }
+
+ if (!(b = cram_read_block(fd))) {
+ cram_free_container(c);
+ return NULL;
+ }
+ if (cram_uncompress_block(b) != 0) {
+ cram_free_container(c);
+ return NULL;
+ }
+
+ len = b->comp_size + 2 + 4*(CRAM_MAJOR_VERS(fd->version) >= 3) +
+ itf8_size(b->content_id) +
+ itf8_size(b->uncomp_size) +
+ itf8_size(b->comp_size);
+
+ /* Extract header from 1st block */
+ if (-1 == int32_get_blk(b, &header_len) ||
+ header_len < 0 || /* Spec. says signed... why? */
+ b->uncomp_size - 4 < header_len) {
+ cram_free_container(c);
+ cram_free_block(b);
+ return NULL;
+ }
+ if (NULL == (header = malloc((size_t) header_len+1))) {
+ cram_free_container(c);
+ cram_free_block(b);
+ return NULL;
+ }
+ memcpy(header, BLOCK_END(b), header_len);
+ header[header_len]='\0';
+ cram_free_block(b);
+
+ /* Consume any remaining blocks */
+ for (i = 1; i < c->num_blocks; i++) {
+ if (!(b = cram_read_block(fd))) {
+ cram_free_container(c);
+ return NULL;
+ }
+ len += b->comp_size + 2 + 4*(CRAM_MAJOR_VERS(fd->version) >= 3) +
+ itf8_size(b->content_id) +
+ itf8_size(b->uncomp_size) +
+ itf8_size(b->comp_size);
+ cram_free_block(b);
+ }
+
+ if (c->length > 0 && len > 0 && c->length > len) {
+ // Consume padding
+ char *pads = malloc(c->length - len);
+ if (!pads) {
+ cram_free_container(c);
+ return NULL;
+ }
+
+ if (c->length - len != hread(fd->fp, pads, c->length - len)) {
+ cram_free_container(c);
+ return NULL;
+ }
+ free(pads);
+ }
+
+ cram_free_container(c);
+ }
+
+ /* Parse */
+ hdr = sam_hdr_parse_(header, header_len);
+ free(header);
+
+ return hdr;
+}
+
+/*
+ * Converts 'in' to a full pathname to store in out.
+ * Out must be at least PATH_MAX bytes long.
+ */
+static void full_path(char *out, char *in) {
+ if (*in == '/') {
+ strncpy(out, in, PATH_MAX);
+ out[PATH_MAX-1] = 0;
+ } else {
+ int len;
+
+ // unable to get dir or out+in is too long
+ if (!getcwd(out, PATH_MAX) ||
+ (len = strlen(out))+1+strlen(in) >= PATH_MAX) {
+ strncpy(out, in, PATH_MAX);
+ out[PATH_MAX-1] = 0;
+ return;
+ }
+
+ sprintf(out+len, "/%.*s", PATH_MAX - len, in);
+
+ // FIXME: cope with `pwd`/../../../foo.fa ?
+ }
+}
+
+/*
+ * Writes a CRAM SAM header.
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_write_SAM_hdr(cram_fd *fd, SAM_hdr *hdr) {
+ int header_len;
+ int blank_block = (CRAM_MAJOR_VERS(fd->version) >= 3);
+
+ /* Write CRAM MAGIC if not yet written. */
+ if (fd->file_def->major_version == 0) {
+ fd->file_def->major_version = CRAM_MAJOR_VERS(fd->version);
+ fd->file_def->minor_version = CRAM_MINOR_VERS(fd->version);
+ if (0 != cram_write_file_def(fd, fd->file_def))
+ return -1;
+ }
+
+ /* 1.0 requires an UNKNOWN read-group */
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ if (!sam_hdr_find_rg(hdr, "UNKNOWN"))
+ if (sam_hdr_add(hdr, "RG",
+ "ID", "UNKNOWN", "SM", "UNKNOWN", NULL))
+ return -1;
+ }
+
+ /* Fix M5 strings */
+ if (fd->refs && !fd->no_ref) {
+ int i;
+ for (i = 0; i < hdr->nref; i++) {
+ SAM_hdr_type *ty;
+ char *ref;
+
+ if (!(ty = sam_hdr_find(hdr, "SQ", "SN", hdr->ref[i].name)))
+ return -1;
+
+ if (!sam_hdr_find_key(hdr, ty, "M5", NULL)) {
+ char unsigned buf[16];
+ char buf2[33];
+ int rlen;
+ hts_md5_context *md5;
+
+ if (!fd->refs ||
+ !fd->refs->ref_id ||
+ !fd->refs->ref_id[i]) {
+ return -1;
+ }
+ rlen = fd->refs->ref_id[i]->length;
+ if (!(md5 = hts_md5_init()))
+ return -1;
+ ref = cram_get_ref(fd, i, 1, rlen);
+ if (NULL == ref) return -1;
+ rlen = fd->refs->ref_id[i]->length; /* In case it just loaded */
+ hts_md5_update(md5, ref, rlen);
+ hts_md5_final(buf, md5);
+ hts_md5_destroy(md5);
+ cram_ref_decr(fd->refs, i);
+
+ hts_md5_hex(buf2, buf);
+ if (sam_hdr_update(hdr, ty, "M5", buf2, NULL))
+ return -1;
+ }
+
+ if (fd->ref_fn) {
+ char ref_fn[PATH_MAX];
+ full_path(ref_fn, fd->ref_fn);
+ if (sam_hdr_update(hdr, ty, "UR", ref_fn, NULL))
+ return -1;
+ }
+ }
+ }
+
+ if (sam_hdr_rebuild(hdr))
+ return -1;
+
+ /* Length */
+ header_len = sam_hdr_length(hdr);
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ if (-1 == int32_encode(fd, header_len))
+ return -1;
+
+ /* Text data */
+ if (header_len != hwrite(fd->fp, sam_hdr_str(hdr), header_len))
+ return -1;
+ } else {
+ /* Create block(s) inside a container */
+ cram_block *b = cram_new_block(FILE_HEADER, 0);
+ cram_container *c = cram_new_container(0, 0);
+ int padded_length;
+ char *pads;
+ int is_cram_3 = (CRAM_MAJOR_VERS(fd->version) >= 3);
+
+ if (!b || !c) {
+ if (b) cram_free_block(b);
+ if (c) cram_free_container(c);
+ return -1;
+ }
+
+ int32_put_blk(b, header_len);
+ BLOCK_APPEND(b, sam_hdr_str(hdr), header_len);
+ BLOCK_UPLEN(b);
+
+ // Compress header block if V3.0 and above
+ if (CRAM_MAJOR_VERS(fd->version) >= 3)
+ cram_compress_block(fd, b, NULL, -1, -1);
+
+ if (blank_block) {
+ c->length = b->comp_size + 2 + 4*is_cram_3 +
+ itf8_size(b->content_id) +
+ itf8_size(b->uncomp_size) +
+ itf8_size(b->comp_size);
+
+ c->num_blocks = 2;
+ c->num_landmarks = 2;
+ if (!(c->landmark = malloc(2*sizeof(*c->landmark)))) {
+ cram_free_block(b);
+ cram_free_container(c);
+ return -1;
+ }
+ c->landmark[0] = 0;
+ c->landmark[1] = c->length;
+
+ // Plus extra storage for uncompressed secondary blank block
+ padded_length = MIN(c->length*.5, 10000);
+ c->length += padded_length + 2 + 4*is_cram_3 +
+ itf8_size(b->content_id) +
+ itf8_size(padded_length)*2;
+ } else {
+ // Pad the block instead.
+ c->num_blocks = 1;
+ c->num_landmarks = 1;
+ if (!(c->landmark = malloc(sizeof(*c->landmark))))
+ return -1;
+ c->landmark[0] = 0;
+
+ padded_length = MAX(c->length*1.5, 10000) - c->length;
+
+ c->length = b->comp_size + padded_length +
+ 2 + 4*is_cram_3 +
+ itf8_size(b->content_id) +
+ itf8_size(b->uncomp_size) +
+ itf8_size(b->comp_size);
+
+ if (NULL == (pads = calloc(1, padded_length))) {
+ cram_free_block(b);
+ cram_free_container(c);
+ return -1;
+ }
+ BLOCK_APPEND(b, pads, padded_length);
+ BLOCK_UPLEN(b);
+ free(pads);
+ }
+
+ if (-1 == cram_write_container(fd, c)) {
+ cram_free_block(b);
+ cram_free_container(c);
+ return -1;
+ }
+
+ if (-1 == cram_write_block(fd, b)) {
+ cram_free_block(b);
+ cram_free_container(c);
+ return -1;
+ }
+
+ if (blank_block) {
+ BLOCK_RESIZE(b, padded_length);
+ memset(BLOCK_DATA(b), 0, padded_length);
+ BLOCK_SIZE(b) = padded_length;
+ BLOCK_UPLEN(b);
+ b->method = RAW;
+ if (-1 == cram_write_block(fd, b)) {
+ cram_free_block(b);
+ cram_free_container(c);
+ return -1;
+ }
+ }
+
+ cram_free_block(b);
+ cram_free_container(c);
+ }
+
+ if (-1 == refs_from_header(fd->refs, fd, fd->header))
+ return -1;
+ if (-1 == refs2id(fd->refs, fd->header))
+ return -1;
+
+ if (0 != hflush(fd->fp))
+ return -1;
+
+ RP("=== Finishing saving header ===\n");
+
+ return 0;
+}
+
+/* ----------------------------------------------------------------------
+ * The top-level cram opening, closing and option handling
+ */
+
+/*
+ * Initialises the lookup tables. These could be global statics, but they're
+ * clumsy to setup in a multi-threaded environment unless we generate
+ * verbatim code and include that.
+ */
+static void cram_init_tables(cram_fd *fd) {
+ int i;
+
+ memset(fd->L1, 4, 256);
+ fd->L1['A'] = 0; fd->L1['a'] = 0;
+ fd->L1['C'] = 1; fd->L1['c'] = 1;
+ fd->L1['G'] = 2; fd->L1['g'] = 2;
+ fd->L1['T'] = 3; fd->L1['t'] = 3;
+
+ memset(fd->L2, 5, 256);
+ fd->L2['A'] = 0; fd->L2['a'] = 0;
+ fd->L2['C'] = 1; fd->L2['c'] = 1;
+ fd->L2['G'] = 2; fd->L2['g'] = 2;
+ fd->L2['T'] = 3; fd->L2['t'] = 3;
+ fd->L2['N'] = 4; fd->L2['n'] = 4;
+
+ if (CRAM_MAJOR_VERS(fd->version) == 1) {
+ for (i = 0; i < 0x200; i++) {
+ int f = 0;
+
+ if (i & CRAM_FPAIRED) f |= BAM_FPAIRED;
+ if (i & CRAM_FPROPER_PAIR) f |= BAM_FPROPER_PAIR;
+ if (i & CRAM_FUNMAP) f |= BAM_FUNMAP;
+ if (i & CRAM_FREVERSE) f |= BAM_FREVERSE;
+ if (i & CRAM_FREAD1) f |= BAM_FREAD1;
+ if (i & CRAM_FREAD2) f |= BAM_FREAD2;
+ if (i & CRAM_FSECONDARY) f |= BAM_FSECONDARY;
+ if (i & CRAM_FQCFAIL) f |= BAM_FQCFAIL;
+ if (i & CRAM_FDUP) f |= BAM_FDUP;
+
+ fd->bam_flag_swap[i] = f;
+ }
+
+ for (i = 0; i < 0x1000; i++) {
+ int g = 0;
+
+ if (i & BAM_FPAIRED) g |= CRAM_FPAIRED;
+ if (i & BAM_FPROPER_PAIR) g |= CRAM_FPROPER_PAIR;
+ if (i & BAM_FUNMAP) g |= CRAM_FUNMAP;
+ if (i & BAM_FREVERSE) g |= CRAM_FREVERSE;
+ if (i & BAM_FREAD1) g |= CRAM_FREAD1;
+ if (i & BAM_FREAD2) g |= CRAM_FREAD2;
+ if (i & BAM_FSECONDARY) g |= CRAM_FSECONDARY;
+ if (i & BAM_FQCFAIL) g |= CRAM_FQCFAIL;
+ if (i & BAM_FDUP) g |= CRAM_FDUP;
+
+ fd->cram_flag_swap[i] = g;
+ }
+ } else {
+ /* NOP */
+ for (i = 0; i < 0x1000; i++)
+ fd->bam_flag_swap[i] = i;
+ for (i = 0; i < 0x1000; i++)
+ fd->cram_flag_swap[i] = i;
+ }
+
+ memset(fd->cram_sub_matrix, 4, 32*32);
+ for (i = 0; i < 32; i++) {
+ fd->cram_sub_matrix[i]['A'&0x1f]=0;
+ fd->cram_sub_matrix[i]['C'&0x1f]=1;
+ fd->cram_sub_matrix[i]['G'&0x1f]=2;
+ fd->cram_sub_matrix[i]['T'&0x1f]=3;
+ fd->cram_sub_matrix[i]['N'&0x1f]=4;
+ }
+ for (i = 0; i < 20; i+=4) {
+ int j;
+ for (j = 0; j < 20; j++) {
+ fd->cram_sub_matrix["ACGTN"[i>>2]&0x1f][j]=3;
+ fd->cram_sub_matrix["ACGTN"[i>>2]&0x1f][j]=3;
+ fd->cram_sub_matrix["ACGTN"[i>>2]&0x1f][j]=3;
+ fd->cram_sub_matrix["ACGTN"[i>>2]&0x1f][j]=3;
+ }
+ fd->cram_sub_matrix["ACGTN"[i>>2]&0x1f][CRAM_SUBST_MATRIX[i+0]&0x1f]=0;
+ fd->cram_sub_matrix["ACGTN"[i>>2]&0x1f][CRAM_SUBST_MATRIX[i+1]&0x1f]=1;
+ fd->cram_sub_matrix["ACGTN"[i>>2]&0x1f][CRAM_SUBST_MATRIX[i+2]&0x1f]=2;
+ fd->cram_sub_matrix["ACGTN"[i>>2]&0x1f][CRAM_SUBST_MATRIX[i+3]&0x1f]=3;
+ }
+}
+
+// Default version numbers for CRAM
+static int major_version = 3;
+static int minor_version = 0;
+
+/*
+ * Opens a CRAM file for read (mode "rb") or write ("wb").
+ * The filename may be "-" to indicate stdin or stdout.
+ *
+ * Returns file handle on success
+ * NULL on failure.
+ */
+cram_fd *cram_open(const char *filename, const char *mode) {
+ hFILE *fp;
+ cram_fd *fd;
+ char fmode[3]= { mode[0], '\0', '\0' };
+
+ if (strlen(mode) > 1 && (mode[1] == 'b' || mode[1] == 'c')) {
+ fmode[1] = 'b';
+ }
+
+ fp = hopen(filename, fmode);
+ if (!fp)
+ return NULL;
+
+ fd = cram_dopen(fp, filename, mode);
+ if (!fd)
+ hclose_abruptly(fp);
+
+ return fd;
+}
+
+/* Opens an existing stream for reading or writing.
+ *
+ * Returns file handle on success;
+ * NULL on failure.
+ */
+cram_fd *cram_dopen(hFILE *fp, const char *filename, const char *mode) {
+ int i;
+ char *cp;
+ cram_fd *fd = calloc(1, sizeof(*fd));
+ if (!fd)
+ return NULL;
+
+ fd->level = 5;
+ for (i = 0; mode[i]; i++) {
+ if (mode[i] >= '0' && mode[i] <= '9') {
+ fd->level = mode[i] - '0';
+ break;
+ }
+ }
+
+ fd->fp = fp;
+ fd->mode = *mode;
+ fd->first_container = 0;
+
+ if (fd->mode == 'r') {
+ /* Reader */
+
+ if (!(fd->file_def = cram_read_file_def(fd)))
+ goto err;
+
+ fd->version = fd->file_def->major_version * 256 +
+ fd->file_def->minor_version;
+
+ if (!(fd->header = cram_read_SAM_hdr(fd)))
+ goto err;
+
+ } else {
+ /* Writer */
+ cram_file_def *def = calloc(1, sizeof(*def));
+ if (!def)
+ return NULL;
+
+ fd->file_def = def;
+
+ def->magic[0] = 'C';
+ def->magic[1] = 'R';
+ def->magic[2] = 'A';
+ def->magic[3] = 'M';
+ def->major_version = 0; // Indicator to write file def later.
+ def->minor_version = 0;
+ memset(def->file_id, 0, 20);
+ strncpy(def->file_id, filename, 20);
+
+ fd->version = major_version * 256 + minor_version;
+
+ /* SAM header written later along with this file_def */
+ }
+
+ cram_init_tables(fd);
+
+ fd->prefix = strdup((cp = strrchr(filename, '/')) ? cp+1 : filename);
+ if (!fd->prefix)
+ goto err;
+ fd->first_base = fd->last_base = -1;
+ fd->record_counter = 0;
+
+ fd->ctr = NULL;
+ fd->refs = refs_create();
+ if (!fd->refs)
+ goto err;
+ fd->ref_id = -2;
+ fd->ref = NULL;
+
+ fd->decode_md = 0;
+ fd->verbose = 0;
+ fd->seqs_per_slice = SEQS_PER_SLICE;
+ fd->slices_per_container = SLICE_PER_CNT;
+ fd->embed_ref = 0;
+ fd->no_ref = 0;
+ fd->ignore_md5 = 0;
+ fd->use_bz2 = 0;
+ fd->use_rans = (CRAM_MAJOR_VERS(fd->version) >= 3);
+ fd->use_lzma = 0;
+ fd->multi_seq = -1;
+ fd->unsorted = 0;
+ fd->shared_ref = 0;
+
+ fd->index = NULL;
+ fd->own_pool = 0;
+ fd->pool = NULL;
+ fd->rqueue = NULL;
+ fd->job_pending = NULL;
+ fd->ooc = 0;
+ fd->required_fields = INT_MAX;
+
+ for (i = 0; i < DS_END; i++)
+ fd->m[i] = cram_new_metrics();
+
+ fd->range.refid = -2; // no ref.
+ fd->eof = 1; // See samtools issue #150
+ fd->ref_fn = NULL;
+
+ fd->bl = NULL;
+
+ /* Initialise dummy refs from the @SQ headers */
+ if (-1 == refs_from_header(fd->refs, fd, fd->header))
+ goto err;
+
+ return fd;
+
+ err:
+ if (fd)
+ free(fd);
+
+ return NULL;
+}
+
+/*
+ * Seek within a CRAM file.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_seek(cram_fd *fd, off_t offset, int whence) {
+ char buf[65536];
+
+ fd->ooc = 0;
+
+ if (hseek(fd->fp, offset, whence) >= 0)
+ return 0;
+
+ if (!(whence == SEEK_CUR && offset >= 0))
+ return -1;
+
+ /* Couldn't fseek, but we're in SEEK_CUR mode so read instead */
+ while (offset > 0) {
+ int len = MIN(65536, offset);
+ if (len != hread(fd->fp, buf, len))
+ return -1;
+ offset -= len;
+ }
+
+ return 0;
+}
+
+/*
+ * Flushes a CRAM file.
+ * Useful for when writing to stdout without wishing to close the stream.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_flush(cram_fd *fd) {
+ if (!fd)
+ return -1;
+
+ if (fd->mode == 'w' && fd->ctr) {
+ if(fd->ctr->slice)
+ fd->ctr->curr_slice++;
+ if (-1 == cram_flush_container_mt(fd, fd->ctr))
+ return -1;
+ }
+
+ return 0;
+}
+
+/*
+ * Closes a CRAM file.
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_close(cram_fd *fd) {
+ spare_bams *bl, *next;
+ int i;
+
+ if (!fd)
+ return -1;
+
+ if (fd->mode == 'w' && fd->ctr) {
+ if(fd->ctr->slice)
+ fd->ctr->curr_slice++;
+ if (-1 == cram_flush_container_mt(fd, fd->ctr))
+ return -1;
+ }
+
+ if (fd->pool && fd->eof >= 0) {
+ t_pool_flush(fd->pool);
+
+ if (0 != cram_flush_result(fd))
+ return -1;
+
+ pthread_mutex_destroy(&fd->metrics_lock);
+ pthread_mutex_destroy(&fd->ref_lock);
+ pthread_mutex_destroy(&fd->bam_list_lock);
+
+ fd->ctr = NULL; // prevent double freeing
+
+ //fprintf(stderr, "CRAM: destroy queue %p\n", fd->rqueue);
+
+ t_results_queue_destroy(fd->rqueue);
+ }
+
+ if (fd->mode == 'w') {
+ /* Write EOF block */
+ if (CRAM_MAJOR_VERS(fd->version) == 3) {
+ if (38 != hwrite(fd->fp,
+ "\x0f\x00\x00\x00\xff\xff\xff\xff" // Cont HDR
+ "\x0f\xe0\x45\x4f\x46\x00\x00\x00" // Cont HDR
+ "\x00\x01\x00" // Cont HDR
+ "\x05\xbd\xd9\x4f" // CRC32
+ "\x00\x01\x00\x06\x06" // Comp.HDR blk
+ "\x01\x00\x01\x00\x01\x00" // Comp.HDR blk
+ "\xee\x63\x01\x4b", // CRC32
+ 38))
+ return -1;
+ } else {
+ if (30 != hwrite(fd->fp,
+ "\x0b\x00\x00\x00\xff\xff\xff\xff"
+ "\x0f\xe0\x45\x4f\x46\x00\x00\x00"
+ "\x00\x01\x00\x00\x01\x00\x06\x06"
+ "\x01\x00\x01\x00\x01\x00", 30))
+ return -1;
+ }
+ }
+
+ for (bl = fd->bl; bl; bl = next) {
+ int i, max_rec = fd->seqs_per_slice * fd->slices_per_container;
+
+ next = bl->next;
+ for (i = 0; i < max_rec; i++) {
+ if (bl->bams[i])
+ bam_free(bl->bams[i]);
+ }
+ free(bl->bams);
+ free(bl);
+ }
+
+ if (hclose(fd->fp) != 0)
+ return -1;
+
+ if (fd->file_def)
+ cram_free_file_def(fd->file_def);
+
+ if (fd->header)
+ sam_hdr_free(fd->header);
+
+ free(fd->prefix);
+
+ if (fd->ctr)
+ cram_free_container(fd->ctr);
+
+ if (fd->refs)
+ refs_free(fd->refs);
+ if (fd->ref_free)
+ free(fd->ref_free);
+
+ for (i = 0; i < DS_END; i++)
+ if (fd->m[i])
+ free(fd->m[i]);
+
+ if (fd->index)
+ cram_index_free(fd);
+
+ if (fd->own_pool && fd->pool)
+ t_pool_destroy(fd->pool, 0);
+
+ free(fd);
+ return 0;
+}
+
+/*
+ * Returns 1 if we hit an EOF while reading.
+ */
+int cram_eof(cram_fd *fd) {
+ return fd->eof;
+}
+
+
+/*
+ * Sets options on the cram_fd. See CRAM_OPT_* definitions in cram_structs.h.
+ * Use this immediately after opening.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_set_option(cram_fd *fd, enum hts_fmt_option opt, ...) {
+ int r;
+ va_list args;
+
+ va_start(args, opt);
+ r = cram_set_voption(fd, opt, args);
+ va_end(args);
+
+ return r;
+}
+
+/*
+ * Sets options on the cram_fd. See CRAM_OPT_* definitions in cram_structs.h.
+ * Use this immediately after opening.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_set_voption(cram_fd *fd, enum hts_fmt_option opt, va_list args) {
+ refs_t *refs;
+
+ if (!fd) {
+ errno = EBADF;
+ return -1;
+ }
+
+ switch (opt) {
+ case CRAM_OPT_DECODE_MD:
+ fd->decode_md = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_PREFIX:
+ if (fd->prefix)
+ free(fd->prefix);
+ if (!(fd->prefix = strdup(va_arg(args, char *))))
+ return -1;
+ break;
+
+ case CRAM_OPT_VERBOSITY:
+ fd->verbose = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_SEQS_PER_SLICE:
+ fd->seqs_per_slice = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_SLICES_PER_CONTAINER:
+ fd->slices_per_container = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_EMBED_REF:
+ fd->embed_ref = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_NO_REF:
+ fd->no_ref = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_IGNORE_MD5:
+ fd->ignore_md5 = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_USE_BZIP2:
+ fd->use_bz2 = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_USE_RANS:
+ fd->use_rans = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_USE_LZMA:
+ fd->use_lzma = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_SHARED_REF:
+ fd->shared_ref = 1;
+ refs = va_arg(args, refs_t *);
+ if (refs != fd->refs) {
+ if (fd->refs)
+ refs_free(fd->refs);
+ fd->refs = refs;
+ fd->refs->count++;
+ }
+ break;
+
+ case CRAM_OPT_RANGE:
+ fd->range = *va_arg(args, cram_range *);
+ return cram_seek_to_refpos(fd, &fd->range);
+
+ case CRAM_OPT_REFERENCE:
+ return cram_load_reference(fd, va_arg(args, char *));
+
+ case CRAM_OPT_VERSION: {
+ int major, minor;
+ char *s = va_arg(args, char *);
+ if (2 != sscanf(s, "%d.%d", &major, &minor)) {
+ fprintf(stderr, "Malformed version string %s\n", s);
+ return -1;
+ }
+ if (!((major == 1 && minor == 0) ||
+ (major == 2 && (minor == 0 || minor == 1)) ||
+ (major == 3 && minor == 0))) {
+ fprintf(stderr, "Unknown version string; "
+ "use 1.0, 2.0, 2.1 or 3.0\n");
+ errno = EINVAL;
+ return -1;
+ }
+ fd->version = major*256 + minor;
+
+ if (CRAM_MAJOR_VERS(fd->version) >= 3)
+ fd->use_rans = 1;
+ break;
+ }
+
+ case CRAM_OPT_MULTI_SEQ_PER_SLICE:
+ fd->multi_seq = va_arg(args, int);
+ break;
+
+ case CRAM_OPT_NTHREADS: {
+ int nthreads = va_arg(args, int);
+ if (nthreads > 1) {
+ if (!(fd->pool = t_pool_init(nthreads*2, nthreads)))
+ return -1;
+
+ fd->rqueue = t_results_queue_init();
+ pthread_mutex_init(&fd->metrics_lock, NULL);
+ pthread_mutex_init(&fd->ref_lock, NULL);
+ pthread_mutex_init(&fd->bam_list_lock, NULL);
+ fd->shared_ref = 1;
+ fd->own_pool = 1;
+ }
+ break;
+ }
+
+ case CRAM_OPT_THREAD_POOL:
+ fd->pool = va_arg(args, t_pool *);
+ if (fd->pool) {
+ fd->rqueue = t_results_queue_init();
+ pthread_mutex_init(&fd->metrics_lock, NULL);
+ pthread_mutex_init(&fd->ref_lock, NULL);
+ pthread_mutex_init(&fd->bam_list_lock, NULL);
+ }
+ fd->shared_ref = 1; // Needed to avoid clobbering ref between threads
+ fd->own_pool = 0;
+
+ //fd->qsize = 1;
+ //fd->decoded = calloc(fd->qsize, sizeof(cram_container *));
+ //t_pool_dispatch(fd->pool, cram_decoder_thread, fd);
+ break;
+
+ case CRAM_OPT_REQUIRED_FIELDS:
+ fd->required_fields = va_arg(args, int);
+ break;
+
+ case HTS_OPT_COMPRESSION_LEVEL:
+ fd->level = va_arg(args, int);
+ break;
+
+ default:
+ fprintf(stderr, "Unknown CRAM option code %d\n", opt);
+ errno = EINVAL;
+ return -1;
+ }
+
+ return 0;
+}
--- /dev/null
+/*
+Copyright (c) 2012-2014 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*! \file
+ * Include cram.h instead.
+ *
+ * This is an internal part of the CRAM system and is automatically included
+ * when you #include cram.h.
+ *
+ * Implements the low level CRAM I/O primitives.
+ * This includes basic data types such as byte, int, ITF-8,
+ * maps, bitwise I/O, etc.
+ */
+
+#ifndef _CRAM_IO_H_
+#define _CRAM_IO_H_
+
+#define ITF8_MACROS
+
+#include <stdint.h>
+#include <cram/misc.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/**@{ ----------------------------------------------------------------------
+ * ITF8 encoding and decoding.
+ *
+ * Also see the itf8_get and itf8_put macros.
+ */
+
+/*! INTERNAL: Converts two characters into an integer for use in switch{} */
+#define CRAM_KEY(a,b) (((a)<<8)|((b)))
+
+/*! Reads an integer in ITF-8 encoding from 'fd' and stores it in
+ * *val.
+ *
+ * @return
+ * Returns the number of bytes read on success;
+ * -1 on failure
+ */
+int itf8_decode(cram_fd *fd, int32_t *val);
+
+#ifndef ITF8_MACROS
+/*! Reads an integer in ITF-8 encoding from 'cp' and stores it in
+ * *val.
+ *
+ * @return
+ * Returns the number of bytes read on success;
+ * -1 on failure
+ */
+int itf8_get(char *cp, int32_t *val_p);
+
+/*! Stores a value to memory in ITF-8 format.
+ *
+ * @return
+ * Returns the number of bytes required to store the number.
+ * This is a maximum of 5 bytes.
+ */
+int itf8_put(char *cp, int32_t val);
+
+#else
+
+/*
+ * Macro implementations of the above
+ */
+#define itf8_get(c,v) (((uc)(c)[0]<0x80)?(*(v)=(uc)(c)[0],1):(((uc)(c)[0]<0xc0)?(*(v)=(((uc)(c)[0]<<8)|(uc)(c)[1])&0x3fff,2):(((uc)(c)[0]<0xe0)?(*(v)=(((uc)(c)[0]<<16)|((uc)(c)[1]<<8)|(uc)(c)[2])&0x1fffff,3):(((uc)(c)[0]<0xf0)?(*(v)=(((uc)(c)[0]<<24)|((uc)(c)[1]<<16)|((uc)(c)[2]<<8)|(uc)(c)[3])&0x0fffffff,4):(*(v)=(((uc)(c)[0]&0x0f)<<28)|((uc)(c)[1]<<20)|((uc)(c)[2]<<12)|((uc)(c)[3]<<4)|((uc)(c)[4]&0x0f),5)))))
+
+#define itf8_put(c,v) ((!((v)&~0x7f))?((c)[0]=(v),1):(!((v)&~0x3fff))?((c)[0]=((v)>>8)|0x80,(c)[1]=(v)&0xff,2):(!((v)&~0x1fffff))?((c)[0]=((v)>>16)|0xc0,(c)[1]=((v)>>8)&0xff,(c)[2]=(v)&0xff,3):(!((v)&~0xfffffff))?((c)[0]=((v)>>24)|0xe0,(c)[1]=((v)>>16)&0xff,(c)[2]=((v)>>8)&0xff,(c)[3]=(v)&0xff,4):((c)[0]=0xf0|(((v)>>28)&0xff),(c)[1]=((v)>>20)&0xff,(c)[2]=((v)>>12)&0xff,(c)[3]=((v)>>4)&0xff,(c)[4]=(v)&0xf,5))
+
+#define itf8_size(v) ((!((v)&~0x7f))?1:(!((v)&~0x3fff))?2:(!((v)&~0x1fffff))?3:(!((v)&~0xfffffff))?4:5)
+
+#endif
+
+int ltf8_get(char *cp, int64_t *val_p);
+int ltf8_put(char *cp, int64_t val);
+
+ /* Version of itf8_get that checks it hasn't run out of input */
+
+extern const int itf8_bytes[16];
+
+static inline int safe_itf8_get(const char *cp, const char *endp,
+ int32_t *val_p) {
+ const unsigned char *up = (unsigned char *)cp;
+
+ if (endp - cp < 5 &&
+ (cp >= endp || endp - cp < itf8_bytes[up[0]>>4])) {
+ *val_p = 0;
+ return 0;
+ }
+
+ if (up[0] < 0x80) {
+ *val_p = up[0];
+ return 1;
+ } else if (up[0] < 0xc0) {
+ *val_p = ((up[0] <<8) | up[1]) & 0x3fff;
+ return 2;
+ } else if (up[0] < 0xe0) {
+ *val_p = ((up[0]<<16) | (up[1]<< 8) | up[2]) & 0x1fffff;
+ return 3;
+ } else if (up[0] < 0xf0) {
+ *val_p = ((up[0]<<24) | (up[1]<<16) | (up[2]<<8) | up[3]) & 0x0fffffff;
+ return 4;
+ } else {
+ *val_p = ((up[0] & 0x0f)<<28) | (up[1]<<20) | (up[2]<<12) | (up[3]<<4) | (up[4] & 0x0f);
+ return 5;
+ }
+}
+
+/*! Pushes a value in ITF8 format onto the end of a block.
+ *
+ * This shouldn't be used for high-volume data as it is not the fastest
+ * method.
+ *
+ * @return
+ * Returns the number of bytes written
+ */
+int itf8_put_blk(cram_block *blk, int val);
+
+/*! Pulls a literal 32-bit value from a block.
+ *
+ * @returns the number of bytes decoded;
+ * -1 on failure.
+ */
+int int32_get_blk(cram_block *b, int32_t *val);
+
+/*! Pushes a literal 32-bit value onto the end of a block.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure.
+ */
+int int32_put_blk(cram_block *blk, int32_t val);
+
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * CRAM blocks - the dynamically growable data block. We have code to
+ * create, update, (un)compress and read/write.
+ *
+ * These are derived from the deflate_interlaced.c blocks, but with the
+ * CRAM extension of content types and IDs.
+ */
+
+/*! Allocates a new cram_block structure with a specified content_type and
+ * id.
+ *
+ * @return
+ * Returns block pointer on success;
+ * NULL on failure
+ */
+cram_block *cram_new_block(enum cram_content_type content_type,
+ int content_id);
+
+/*! Reads a block from a cram file.
+ *
+ * @return
+ * Returns cram_block pointer on success;
+ * NULL on failure
+ */
+cram_block *cram_read_block(cram_fd *fd);
+
+/*! Writes a CRAM block.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_write_block(cram_fd *fd, cram_block *b);
+
+/*! Frees a CRAM block, deallocating internal data too.
+ */
+void cram_free_block(cram_block *b);
+
+/*! Uncompress a memory block using Zlib.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+char *zlib_mem_inflate(char *cdata, size_t csize, size_t *size);
+
+/*! Uncompresses a CRAM block, if compressed.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_uncompress_block(cram_block *b);
+
+/*! Compresses a block.
+ *
+ * Compresses a block using one of two different zlib strategies. If we only
+ * want one choice set strat2 to be -1.
+ *
+ * The logic here is that sometimes Z_RLE does a better job than Z_FILTERED
+ * or Z_DEFAULT_STRATEGY on quality data. If so, we'd rather use it as it is
+ * significantly faster.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_compress_block(cram_fd *fd, cram_block *b, cram_metrics *metrics,
+ int method, int level);
+
+cram_metrics *cram_new_metrics(void);
+char *cram_block_method2str(enum cram_block_method m);
+char *cram_content_type2str(enum cram_content_type t);
+
+/*
+ * Find an external block by its content_id
+ */
+
+static inline cram_block *cram_get_block_by_id(cram_slice *slice, int id) {
+ if (slice->block_by_id && id >= 0 && id < 1024) {
+ return slice->block_by_id[id];
+ } else {
+ int i;
+ for (i = 0; i < slice->hdr->num_blocks; i++) {
+ cram_block *b = slice->block[i];
+ if (b && b->content_type == EXTERNAL && b->content_id == id)
+ return b;
+ }
+ }
+ return NULL;
+}
+
+/* --- Accessor macros for manipulating blocks on a byte by byte basis --- */
+
+/* Block size and data pointer. */
+#define BLOCK_SIZE(b) ((b)->byte)
+#define BLOCK_DATA(b) ((b)->data)
+
+/* Returns the address one past the end of the block */
+#define BLOCK_END(b) (&(b)->data[(b)->byte])
+
+/* Request block to be at least 'l' bytes long */
+#define BLOCK_RESIZE(b,l) \
+ do { \
+ while((b)->alloc <= (l)) { \
+ (b)->alloc = (b)->alloc ? (b)->alloc*1.5 : 1024; \
+ (b)->data = realloc((b)->data, (b)->alloc); \
+ } \
+ } while(0)
+
+/* Make block exactly 'l' bytes long */
+#define BLOCK_RESIZE_EXACT(b,l) \
+ do { \
+ (b)->alloc = (l); \
+ (b)->data = realloc((b)->data, (b)->alloc); \
+ } while(0)
+
+/* Ensure the block can hold at least another 'l' bytes */
+#define BLOCK_GROW(b,l) BLOCK_RESIZE((b), BLOCK_SIZE((b)) + (l))
+
+/* Append string 's' of length 'l' */
+#define BLOCK_APPEND(b,s,l) \
+ do { \
+ BLOCK_GROW((b),(l)); \
+ memcpy(BLOCK_END((b)), (s), (l)); \
+ BLOCK_SIZE((b)) += (l); \
+ } while (0)
+
+/* Append as single character 'c' */
+#define BLOCK_APPEND_CHAR(b,c) \
+ do { \
+ BLOCK_GROW((b),1); \
+ (b)->data[(b)->byte++] = (c); \
+ } while (0)
+
+/* Append a single unsigned integer */
+#define BLOCK_APPEND_UINT(b,i) \
+ do { \
+ unsigned char *cp; \
+ BLOCK_GROW((b),11); \
+ cp = &(b)->data[(b)->byte]; \
+ (b)->byte += append_uint32(cp, (i)) - cp; \
+ } while (0)
+
+static inline unsigned char *append_uint32(unsigned char *cp, uint32_t i) {
+ uint32_t j;
+
+ if (i == 0) {
+ *cp++ = '0';
+ return cp;
+ }
+
+ if (i < 100) goto b1;
+ if (i < 10000) goto b3;
+ if (i < 1000000) goto b5;
+ if (i < 100000000) goto b7;
+
+ if ((j = i / 1000000000)) {*cp++ = j + '0'; i -= j*1000000000; goto x8;}
+ if ((j = i / 100000000)) {*cp++ = j + '0'; i -= j*100000000; goto x7;}
+ b7:if ((j = i / 10000000)) {*cp++ = j + '0'; i -= j*10000000; goto x6;}
+ if ((j = i / 1000000)) {*cp++ = j + '0', i -= j*1000000; goto x5;}
+ b5:if ((j = i / 100000)) {*cp++ = j + '0', i -= j*100000; goto x4;}
+ if ((j = i / 10000)) {*cp++ = j + '0', i -= j*10000; goto x3;}
+ b3:if ((j = i / 1000)) {*cp++ = j + '0', i -= j*1000; goto x2;}
+ if ((j = i / 100)) {*cp++ = j + '0', i -= j*100; goto x1;}
+ b1:if ((j = i / 10)) {*cp++ = j + '0', i -= j*10; goto x0;}
+ if (i) *cp++ = i + '0';
+ return cp;
+
+ x8: *cp++ = i / 100000000 + '0', i %= 100000000;
+ x7: *cp++ = i / 10000000 + '0', i %= 10000000;
+ x6: *cp++ = i / 1000000 + '0', i %= 1000000;
+ x5: *cp++ = i / 100000 + '0', i %= 100000;
+ x4: *cp++ = i / 10000 + '0', i %= 10000;
+ x3: *cp++ = i / 1000 + '0', i %= 1000;
+ x2: *cp++ = i / 100 + '0', i %= 100;
+ x1: *cp++ = i / 10 + '0', i %= 10;
+ x0: *cp++ = i + '0';
+
+ return cp;
+}
+
+static inline unsigned char *append_sub32(unsigned char *cp, uint32_t i) {
+ *cp++ = i / 100000000 + '0', i %= 100000000;
+ *cp++ = i / 10000000 + '0', i %= 10000000;
+ *cp++ = i / 1000000 + '0', i %= 1000000;
+ *cp++ = i / 100000 + '0', i %= 100000;
+ *cp++ = i / 10000 + '0', i %= 10000;
+ *cp++ = i / 1000 + '0', i %= 1000;
+ *cp++ = i / 100 + '0', i %= 100;
+ *cp++ = i / 10 + '0', i %= 10;
+ *cp++ = i + '0';
+
+ return cp;
+}
+
+static inline unsigned char *append_uint64(unsigned char *cp, uint64_t i) {
+ uint64_t j;
+
+ if (i <= 0xffffffff)
+ return append_uint32(cp, i);
+
+ if ((j = i/1000000000) > 1000000000) {
+ cp = append_uint32(cp, j/1000000000);
+ j %= 1000000000;
+ cp = append_sub32(cp, j);
+ } else {
+ cp = append_uint32(cp, i / 1000000000);
+ }
+ cp = append_sub32(cp, i % 1000000000);
+
+ return cp;
+}
+
+#define BLOCK_UPLEN(b) \
+ (b)->comp_size = (b)->uncomp_size = BLOCK_SIZE((b))
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * Reference sequence handling
+ */
+
+/*! Loads a reference set from fn and stores in the cram_fd.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_load_reference(cram_fd *fd, char *fn);
+
+/*! Generates a lookup table in refs based on the SQ headers in SAM_hdr.
+ *
+ * Indexes references by the order they appear in a BAM file. This may not
+ * necessarily be the same order they appear in the fasta reference file.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int refs2id(refs_t *r, SAM_hdr *bfd);
+
+void refs_free(refs_t *r);
+
+/*! Returns a portion of a reference sequence from start to end inclusive.
+ *
+ * The returned pointer is owned by the cram_file fd and should not be freed
+ * by the caller. It is valid only until the next cram_get_ref is called
+ * with the same fd parameter (so is thread-safe if given multiple files).
+ *
+ * To return the entire reference sequence, specify start as 1 and end
+ * as 0.
+ *
+ * @return
+ * Returns reference on success;
+ * NULL on failure
+ */
+char *cram_get_ref(cram_fd *fd, int id, int start, int end);
+void cram_ref_incr(refs_t *r, int id);
+void cram_ref_decr(refs_t *r, int id);
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * Containers
+ */
+
+/*! Creates a new container, specifying the maximum number of slices
+ * and records permitted.
+ *
+ * @return
+ * Returns cram_container ptr on success;
+ * NULL on failure
+ */
+cram_container *cram_new_container(int nrec, int nslice);
+void cram_free_container(cram_container *c);
+
+/*! Reads a container header.
+ *
+ * @return
+ * Returns cram_container on success;
+ * NULL on failure or no container left (fd->err == 0).
+ */
+cram_container *cram_read_container(cram_fd *fd);
+
+/*! Writes a container structure.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_write_container(cram_fd *fd, cram_container *h);
+
+/*! Flushes a container to disk.
+ *
+ * Flushes a completely or partially full container to disk, writing
+ * container structure, header and blocks. This also calls the encoder
+ * functions.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_flush_container(cram_fd *fd, cram_container *c);
+int cram_flush_container_mt(cram_fd *fd, cram_container *c);
+
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * Compression headers; the first part of the container
+ */
+
+/*! Creates a new blank container compression header
+ *
+ * @return
+ * Returns header ptr on success;
+ * NULL on failure
+ */
+cram_block_compression_hdr *cram_new_compression_header(void);
+
+/*! Frees a cram_block_compression_hdr */
+void cram_free_compression_header(cram_block_compression_hdr *hdr);
+
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * Slices and slice headers
+ */
+
+/*! Frees a slice header */
+void cram_free_slice_header(cram_block_slice_hdr *hdr);
+
+/*! Frees a slice */
+void cram_free_slice(cram_slice *s);
+
+/*! Creates a new empty slice in memory, for subsequent writing to
+ * disk.
+ *
+ * @return
+ * Returns cram_slice ptr on success;
+ * NULL on failure
+ */
+cram_slice *cram_new_slice(enum cram_content_type type, int nrecs);
+
+/*! Loads an entire slice.
+ *
+ * FIXME: In 1.0 the native unit of slices within CRAM is broken
+ * as slices contain references to objects in other slices.
+ * To work around this while keeping the slice oriented outer loop
+ * we read all slices and stitch them together into a fake large
+ * slice instead.
+ *
+ * @return
+ * Returns cram_slice ptr on success;
+ * NULL on failure
+ */
+cram_slice *cram_read_slice(cram_fd *fd);
+
+
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * CRAM file definition (header)
+ */
+
+/*! Reads a CRAM file definition structure.
+ *
+ * @return
+ * Returns file_def ptr on success;
+ * NULL on failure
+ */
+cram_file_def *cram_read_file_def(cram_fd *fd);
+
+/*! Writes a cram_file_def structure to cram_fd.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_write_file_def(cram_fd *fd, cram_file_def *def);
+
+/*! Frees a cram_file_def structure. */
+void cram_free_file_def(cram_file_def *def);
+
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * SAM header I/O
+ */
+
+/*! Reads the SAM header from the first CRAM data block.
+ *
+ * Also performs minimal parsing to extract read-group
+ * and sample information.
+ *
+ * @return
+ * Returns SAM hdr ptr on success;
+ * NULL on failure
+ */
+SAM_hdr *cram_read_SAM_hdr(cram_fd *fd);
+
+/*! Writes a CRAM SAM header.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_write_SAM_hdr(cram_fd *fd, SAM_hdr *hdr);
+
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * The top-level cram opening, closing and option handling
+ */
+
+/*! Opens a CRAM file for read (mode "rb") or write ("wb").
+ *
+ * The filename may be "-" to indicate stdin or stdout.
+ *
+ * @return
+ * Returns file handle on success;
+ * NULL on failure.
+ */
+cram_fd *cram_open(const char *filename, const char *mode);
+
+/*! Opens an existing stream for reading or writing.
+ *
+ * @return
+ * Returns file handle on success;
+ * NULL on failure.
+ */
+cram_fd *cram_dopen(struct hFILE *fp, const char *filename, const char *mode);
+
+/*! Closes a CRAM file.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_close(cram_fd *fd);
+
+/*
+ * Seek within a CRAM file.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_seek(cram_fd *fd, off_t offset, int whence);
+
+/*
+ * Flushes a CRAM file.
+ * Useful for when writing to stdout without wishing to close the stream.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_flush(cram_fd *fd);
+
+/*! Checks for end of file on a cram_fd stream.
+ *
+ * @return
+ * Returns 0 if not at end of file
+ * 1 if we hit an expected EOF (end of range or EOF block)
+ * 2 for other EOF (end of stream without EOF block)
+ */
+int cram_eof(cram_fd *fd);
+
+/*! Sets options on the cram_fd.
+ *
+ * See CRAM_OPT_* definitions in cram_structs.h.
+ * Use this immediately after opening.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_set_option(cram_fd *fd, enum hts_fmt_option opt, ...);
+
+/*! Sets options on the cram_fd.
+ *
+ * See CRAM_OPT_* definitions in cram_structs.h.
+ * Use this immediately after opening.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_set_voption(cram_fd *fd, enum hts_fmt_option opt, va_list args);
+
+/*!
+ * Attaches a header to a cram_fd.
+ *
+ * This should be used when creating a new cram_fd for writing where
+ * we have an SAM_hdr already constructed (eg from a file we've read
+ * in).
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_set_header(cram_fd *fd, SAM_hdr *hdr);
+
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _CRAM_IO_H_ */
--- /dev/null
+/*
+Copyright (c) 2010-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <assert.h>
+#include <string.h>
+#include <stdlib.h>
+
+#include "cram/cram.h"
+#include "htslib/sam.h"
+
+/*---------------------------------------------------------------------------
+ * Samtools compatibility portion
+ */
+int bam_construct_seq(bam_seq_t **bp, size_t extra_len,
+ const char *qname, size_t qname_len,
+ int flag,
+ int rname, // Ref ID
+ int pos,
+ int end, // aligned start/end coords
+ int mapq,
+ uint32_t ncigar, const uint32_t *cigar,
+ int mrnm, // Mate Ref ID
+ int mpos,
+ int isize,
+ int len,
+ const char *seq,
+ const char *qual) {
+ static const char L[256] = {
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15, 0,15,15,
+ 15, 1,14, 2,13,15,15, 4,11,15,15,12,15, 3,15,15,
+ 15,15, 5, 6, 8,15, 7, 9,15,10,15,15,15,15,15,15,
+ 15, 1,14, 2,13,15,15, 4,11,15,15,12,15, 3,15,15,
+ 15,15, 5, 6, 8,15, 7, 9,15,10,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,
+ 15,15,15,15,15,15,15,15,15,15,15,15,15,15,15,15
+ };
+ bam1_t *b = (bam1_t *)*bp;
+ uint8_t *cp;
+ int i, bam_len;
+
+ //b->l_aux = extra_len; // we fill this out later
+
+ bam_len = qname_len + 1 + ncigar*4 + (len+1)/2 + len + extra_len;
+ if (b->m_data < bam_len) {
+ b->m_data = bam_len;
+ kroundup32(b->m_data);
+ b->data = (uint8_t*)realloc(b->data, b->m_data);
+ if (!b->data)
+ return -1;
+ }
+ b->l_data = bam_len;
+
+ b->core.tid = rname;
+ b->core.pos = pos-1;
+ b->core.bin = bam_reg2bin(pos, end);
+ b->core.qual = mapq;
+ b->core.l_qname = qname_len+1;
+ b->core.flag = flag;
+ b->core.n_cigar = ncigar;
+ b->core.l_qseq = len;
+ b->core.mtid = mrnm;
+ b->core.mpos = mpos-1;
+ b->core.isize = isize;
+
+ cp = b->data;
+
+ strncpy((char *)cp, qname, qname_len);
+ cp[qname_len] = 0;
+ cp += qname_len+1;
+ memcpy(cp, cigar, ncigar*4);
+ cp += ncigar*4;
+
+ for (i = 0; i+1 < len; i+=2) {
+ *cp++ = (L[(uc)seq[i]]<<4) + L[(uc)seq[i+1]];
+ }
+ if (i < len)
+ *cp++ = L[(uc)seq[i]]<<4;
+
+ if (qual)
+ memcpy(cp, qual, len);
+ else
+ memset(cp, '\xff', len);
+
+ return 0;
+}
+
+bam_hdr_t *cram_header_to_bam(SAM_hdr *h) {
+ int i;
+ bam_hdr_t *header = bam_hdr_init();
+
+ header->l_text = ks_len(&h->text);
+ header->text = malloc(header->l_text+1);
+ memcpy(header->text, ks_str(&h->text), header->l_text);
+ header->text[header->l_text] = 0;
+
+ header->n_targets = h->nref;
+ header->target_name = (char **)calloc(header->n_targets,
+ sizeof(char *));
+ header->target_len = (uint32_t *)calloc(header->n_targets, 4);
+
+ for (i = 0; i < h->nref; i++) {
+ header->target_name[i] = strdup(h->ref[i].name);
+ header->target_len[i] = h->ref[i].len;
+ }
+
+ return header;
+}
+
+SAM_hdr *bam_header_to_cram(bam_hdr_t *h) {
+ return sam_hdr_parse_(h->text, h->l_text);
+}
--- /dev/null
+/*
+Copyright (c) 2010-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _CRAM_SAMTOOLS_H_
+#define _CRAM_SAMTOOLS_H_
+
+/* Samtools compatible API */
+#define bam_blk_size(b) ((b)->l_data)
+#define bam_set_blk_size(b,v) ((b)->data_len = (v))
+
+#define bam_ref(b) (b)->core.tid
+#define bam_pos(b) (b)->core.pos
+#define bam_mate_pos(b) (b)->core.mpos
+#define bam_mate_ref(b) (b)->core.mtid
+#define bam_ins_size(b) (b)->core.isize
+#define bam_seq_len(b) (b)->core.l_qseq
+#define bam_cigar_len(b) (b)->core.n_cigar
+#define bam_flag(b) (b)->core.flag
+#define bam_bin(b) (b)->core.bin
+#define bam_map_qual(b) (b)->core.qual
+#define bam_name_len(b) (b)->core.l_qname
+#define bam_name(b) bam_get_qname((b))
+#define bam_qual(b) bam_get_qual((b))
+#define bam_seq(b) bam_get_seq((b))
+#define bam_cigar(b) bam_get_cigar((b))
+#define bam_aux(b) bam_get_aux((b))
+
+#define bam_dup(b) bam_copy1(bam_init1(), (b))
+
+#define bam_free(b) bam_destroy1((b))
+
+#define bam_reg2bin(beg,end) hts_reg2bin((beg),(end),14,5)
+
+#include "htslib/sam.h"
+
+enum cigar_op {
+ BAM_CMATCH_=BAM_CMATCH,
+ BAM_CINS_=BAM_CINS,
+ BAM_CDEL_=BAM_CDEL,
+ BAM_CREF_SKIP_=BAM_CREF_SKIP,
+ BAM_CSOFT_CLIP_=BAM_CSOFT_CLIP,
+ BAM_CHARD_CLIP_=BAM_CHARD_CLIP,
+ BAM_CPAD_=BAM_CPAD,
+ BAM_CBASE_MATCH=BAM_CEQUAL,
+ BAM_CBASE_MISMATCH=BAM_CDIFF
+};
+
+typedef bam1_t bam_seq_t;
+
+#include "cram/sam_header.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+bam_hdr_t *cram_header_to_bam(SAM_hdr *h);
+SAM_hdr *bam_header_to_cram(bam_hdr_t *h);
+
+int bam_construct_seq(bam_seq_t **bp, size_t extra_len,
+ const char *qname, size_t qname_len,
+ int flag,
+ int rname, // Ref ID
+ int pos,
+ int end, // aligned start/end coords
+ int mapq,
+ uint32_t ncigar, const uint32_t *cigar,
+ int mrnm, // Mate Ref ID
+ int mpos,
+ int isize,
+ int len,
+ const char *seq,
+ const char *qual);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _CRAM_SAMTOOLS_H_ */
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <stdio.h>
+#include <errno.h>
+#include <assert.h>
+#include <stdlib.h>
+#include <string.h>
+#include <zlib.h>
+#include <sys/types.h>
+#include <sys/stat.h>
+#include <math.h>
+#include <ctype.h>
+
+#include "cram/cram.h"
+#include "cram/os.h"
+
+cram_stats *cram_stats_create(void) {
+ return calloc(1, sizeof(cram_stats));
+}
+
+void cram_stats_add(cram_stats *st, int32_t val) {
+ st->nsamp++;
+
+ //assert(val >= 0);
+
+ if (val < MAX_STAT_VAL && val >= 0) {
+ st->freqs[val]++;
+ } else {
+ khint_t k;
+ int r;
+
+ if (!st->h) {
+ st->h = kh_init(m_i2i);
+ }
+
+ k = kh_put(m_i2i, st->h, val, &r);
+ if (r == 0)
+ kh_val(st->h, k)++;
+ else if (r != -1)
+ kh_val(st->h, k) = 1;
+ else
+ ; // FIXME: handle error
+ }
+}
+
+void cram_stats_del(cram_stats *st, int32_t val) {
+ st->nsamp--;
+
+ //assert(val >= 0);
+
+ if (val < MAX_STAT_VAL && val >= 0) {
+ st->freqs[val]--;
+ assert(st->freqs[val] >= 0);
+ } else if (st->h) {
+ khint_t k = kh_get(m_i2i, st->h, val);
+
+ if (k != kh_end(st->h)) {
+ if (--kh_val(st->h, k) == 0)
+ kh_del(m_i2i, st->h, k);
+ } else {
+ fprintf(stderr, "Failed to remove val %d from cram_stats\n", val);
+ st->nsamp++;
+ }
+ } else {
+ fprintf(stderr, "Failed to remove val %d from cram_stats\n", val);
+ st->nsamp++;
+ }
+}
+
+void cram_stats_dump(cram_stats *st) {
+ int i;
+ fprintf(stderr, "cram_stats:\n");
+ for (i = 0; i < MAX_STAT_VAL; i++) {
+ if (!st->freqs[i])
+ continue;
+ fprintf(stderr, "\t%d\t%d\n", i, st->freqs[i]);
+ }
+ if (st->h) {
+ khint_t k;
+ for (k = kh_begin(st->h); k != kh_end(st->h); k++) {
+ if (!kh_exist(st->h, k))
+ continue;
+
+ fprintf(stderr, "\t%d\t%d\n", kh_key(st->h, k), kh_val(st->h, k));
+ }
+ }
+}
+
+#if 1
+/* Returns the number of bits set in val; it the highest bit used */
+static int nbits(int v) {
+ static const int MultiplyDeBruijnBitPosition[32] = {
+ 1, 10, 2, 11, 14, 22, 3, 30, 12, 15, 17, 19, 23, 26, 4, 31,
+ 9, 13, 21, 29, 16, 18, 25, 8, 20, 28, 24, 7, 27, 6, 5, 32
+ };
+
+ v |= v >> 1; // first up to set all bits 1 after the first 1 */
+ v |= v >> 2;
+ v |= v >> 4;
+ v |= v >> 8;
+ v |= v >> 16;
+
+ // DeBruijn magic to find top bit
+ return MultiplyDeBruijnBitPosition[(uint32_t)(v * 0x07C4ACDDU) >> 27];
+}
+#endif
+
+/*
+ * Computes entropy from integer frequencies for various encoding methods and
+ * picks the best encoding.
+ *
+ * FIXME: we could reuse some of the code here for the actual encoding
+ * parameters too. Eg the best 'k' for SUBEXP or the code lengths for huffman.
+ *
+ * Returns the best codec to use.
+ */
+enum cram_encoding cram_stats_encoding(cram_fd *fd, cram_stats *st) {
+ enum cram_encoding best_encoding = E_NULL;
+ int best_size = INT_MAX, bits;
+ int nvals, i, ntot = 0, max_val = 0, min_val = INT_MAX, k;
+ int *vals = NULL, *freqs = NULL, vals_alloc = 0, *codes;
+
+ //cram_stats_dump(st);
+
+ /* Count number of unique symbols */
+ for (nvals = i = 0; i < MAX_STAT_VAL; i++) {
+ if (!st->freqs[i])
+ continue;
+ if (nvals >= vals_alloc) {
+ vals_alloc = vals_alloc ? vals_alloc*2 : 1024;
+ vals = realloc(vals, vals_alloc * sizeof(int));
+ freqs = realloc(freqs, vals_alloc * sizeof(int));
+ if (!vals || !freqs) {
+ if (vals) free(vals);
+ if (freqs) free(freqs);
+ return E_HUFFMAN; // Cannot do much else atm
+ }
+ }
+ vals[nvals] = i;
+ freqs[nvals] = st->freqs[i];
+ ntot += freqs[nvals];
+ if (max_val < i) max_val = i;
+ if (min_val > i) min_val = i;
+ nvals++;
+ }
+ if (st->h) {
+ khint_t k;
+ int i;
+
+ for (k = kh_begin(st->h); k != kh_end(st->h); k++) {
+ if (!kh_exist(st->h, k))
+ continue;
+
+ if (nvals >= vals_alloc) {
+ vals_alloc = vals_alloc ? vals_alloc*2 : 1024;
+ vals = realloc(vals, vals_alloc * sizeof(int));
+ freqs = realloc(freqs, vals_alloc * sizeof(int));
+ if (!vals || !freqs)
+ return E_HUFFMAN; // Cannot do much else atm
+ }
+ i = kh_key(st->h, k);
+ vals[nvals]=i;
+ freqs[nvals] = kh_val(st->h, k);
+ ntot += freqs[nvals];
+ if (max_val < i) max_val = i;
+ if (min_val > i) min_val = i;
+ nvals++;
+ }
+ }
+
+ st->nvals = nvals;
+ assert(ntot == st->nsamp);
+
+ if (nvals <= 1) {
+ free(vals);
+ free(freqs);
+ return E_HUFFMAN;
+ }
+
+ if (fd->verbose > 1)
+ fprintf(stderr, "Range = %d..%d, nvals=%d, ntot=%d\n",
+ min_val, max_val, nvals, ntot);
+
+ /* Theoretical entropy */
+// if (fd->verbose > 1) {
+// double dbits = 0;
+// for (i = 0; i < nvals; i++) {
+// dbits += freqs[i] * log((double)freqs[i]/ntot);
+// }
+// dbits /= -log(2);
+// if (fd->verbose > 1)
+// fprintf(stderr, "Entropy = %f\n", dbits);
+// }
+
+ if (nvals > 1 && ntot > 256) {
+#if 0
+ /*
+ * CRUDE huffman estimator. Round to closest and round up from 0
+ * to 1 bit.
+ *
+ * With and without ITF8 incase we have a few discrete values but with
+ * large magnitude.
+ *
+ * Note rans0/arith0 and Z_HUFFMAN_ONLY vs internal huffman can be
+ * compared in this way, but order-1 (eg rans1) or maybe LZ77 modes
+ * may detect the correlation of high bytes to low bytes in multi-
+ * byte values. So this predictor breaks down.
+ */
+ double dbits = 0; // entropy + ~huffman
+ double dbitsH = 0;
+ double dbitsE = 0; // external entropy + ~huffman
+ double dbitsEH = 0;
+ int F[256] = {0}, n = 0;
+ double e = 0; // accumulated error bits
+ for (i = 0; i < nvals; i++) {
+ double x; int X;
+ unsigned int v = vals[i];
+
+ //Better encoding would cope with sign.
+ //v = ABS(vals[i])*2+(vals[i]<0);
+
+ if (!(v & ~0x7f)) {
+ F[v] += freqs[i], n+=freqs[i];
+ } else if (!(v & ~0x3fff)) {
+ F[(v>>8) |0x80] += freqs[i];
+ F[ v &0xff] += freqs[i], n+=2*freqs[i];
+ } else if (!(v & ~0x1fffff)) {
+ F[(v>>16)|0xc0] += freqs[i];
+ F[(v>>8 )&0xff] += freqs[i];
+ F[ v &0xff] += freqs[i], n+=3*freqs[i];
+ } else if (!(v & ~0x0fffffff)) {
+ F[(v>>24)|0xe0] += freqs[i];
+ F[(v>>16)&0xff] += freqs[i];
+ F[(v>>8 )&0xff] += freqs[i];
+ F[ v &0xff] += freqs[i], n+=4*freqs[i];
+ } else {
+ F[(v>>28)|0xf0] += freqs[i];
+ F[(v>>20)&0xff] += freqs[i];
+ F[(v>>12)&0xff] += freqs[i];
+ F[(v>>4 )&0xff] += freqs[i];
+ F[ v &0x0f] += freqs[i], n+=5*freqs[i];
+ }
+
+ x = -log((double)freqs[i]/ntot)/.69314718055994530941;
+ X = x+0.5;
+ if ((int)(x+((double)e/freqs[i])+.5)>X) {
+ X++;
+ } else if ((int)(x+((double)e/freqs[i])+.5)<X) {
+ X--;
+ }
+ e-=freqs[i]*(X-x);
+ X += (X==0);
+
+ //fprintf(stderr, "Val %d = %d x %d (ent %f, %d) e %f\n", i, v, freqs[i], x, X, e);
+
+ dbits += freqs[i] * x;
+ dbitsH += freqs[i] * X;
+ }
+
+ for (i = 0; i < 256; i++) {
+ if (F[i]) {
+ double x = -log((double)F[i]/n)/.69314718055994530941;
+ int X = x+0.5;
+ X += (X==0);
+ dbitsE += F[i] * x;
+ dbitsEH += F[i] * X;
+
+ //fprintf(stderr, "Val %d = %d x %d (e %f, %d)\n", i, i, F[i], x, X);
+ }
+ }
+
+ //fprintf(stderr, "CORE Entropy = %f, %f\n", dbits/8, dbitsH/8);
+ //fprintf(stderr, "Ext. Entropy = %f, %f\n", dbitsE/8, dbitsEH/8);
+
+ if (dbitsE < 1000 || dbitsE / dbits > 1.1) {
+ //fprintf(stderr, "=> %d < 200 ? E_HUFFMAN : E_BETA\n", nvals);
+ free(vals); free(freqs);
+ return nvals < 200 ? E_HUFFMAN : E_BETA;
+ }
+#endif
+ free(vals); free(freqs);
+ return E_EXTERNAL;
+ }
+
+ /*
+ * Avoid complex stats for now, just do heuristic of HUFFMAN for small
+ * alphabets and BETA for anything large.
+ */
+ free(vals); free(freqs);
+ return nvals < 200 ? E_HUFFMAN : E_BETA;
+ //return E_HUFFMAN;
+ //return E_EXTERNAL;
+
+
+ /* We only support huffman now anyway... */
+ //free(vals); free(freqs); return E_HUFFMAN;
+
+ /* Beta */
+ bits = nbits(max_val - min_val) * ntot;
+ if (fd->verbose > 1)
+ fprintf(stderr, "BETA = %d\n", bits);
+ if (best_size > bits)
+ best_size = bits, best_encoding = E_BETA;
+
+#if 0
+ /* Unary */
+ if (min_val >= 0) {
+ for (bits = i = 0; i < nvals; i++)
+ bits += freqs[i]*(vals[i]+1);
+ if (fd->verbose > 1)
+ fprintf(stderr, "UNARY = %d\n", bits);
+ if (best_size > bits)
+ best_size = bits, best_encoding = E_NULL; //E_UNARY;
+ }
+
+ /* Gamma */
+ for (bits = i = 0; i < nvals; i++)
+ bits += ((nbits(vals[i]-min_val+1)-1) + nbits(vals[i]-min_val+1)) * freqs[i];
+ if (fd->verbose > 1)
+ fprintf(stderr, "GAMMA = %d\n", bits);
+ if (best_size > bits)
+ best_size = bits, best_encoding = E_GAMMA;
+
+ /* Subexponential */
+ for (k = 0; k < 10; k++) {
+ for (bits = i = 0; i < nvals; i++) {
+ if (vals[i]-min_val < (1<<k))
+ bits += (1 + k)*freqs[i];
+ else
+ bits += (nbits(vals[i]-min_val)*2-k)*freqs[i];
+ }
+
+ if (fd->verbose > 1)
+ fprintf(stderr, "SUBEXP%d = %d\n", k, bits);
+ if (best_size > bits)
+ best_size = bits, best_encoding = E_SUBEXP;
+ }
+#endif
+
+ /* byte array len */
+
+ /* byte array stop */
+
+ /* External? Guesswork! */
+
+ /* Huffman */
+// qsort(freqs, nvals, sizeof(freqs[0]), sort_freqs);
+// for (i = 0; i < nvals; i++) {
+// fprintf(stderr, "%d = %d\n", i, freqs[i]);
+// vals[i] = 0;
+// }
+
+ /* Grow freqs to 2*freqs, to store sums */
+ /* Vals holds link data */
+ freqs = realloc(freqs, 2*nvals*sizeof(*freqs));
+ codes = calloc(2*nvals, sizeof(*codes));
+ if (!freqs || !codes)
+ return E_HUFFMAN; // Cannot do much else atm
+
+ /* Inefficient, use pointers to form chain so we can insert and maintain
+ * a sorted list? This is currently O(nvals^2) complexity.
+ */
+ for (;;) {
+ int low1 = INT_MAX, low2 = INT_MAX;
+ int ind1 = 0, ind2 = 0;
+ for (i = 0; i < nvals; i++) {
+ if (freqs[i] < 0)
+ continue;
+ if (low1 > freqs[i])
+ low2 = low1, ind2 = ind1, low1 = freqs[i], ind1 = i;
+ else if (low2 > freqs[i])
+ low2 = freqs[i], ind2 = i;
+ }
+ if (low2 == INT_MAX)
+ break;
+
+ //fprintf(stderr, "Merge ind %d (%d), %d (%d) = %d+%d, => %d=%d\n",
+ // ind1, vals[ind1], ind2, vals[ind2], low1, low2,
+ // nvals, low1+low2);
+
+ freqs[nvals] = low1 + low2;
+ codes[ind1] = nvals;
+ codes[ind2] = nvals;
+ freqs[ind1] *= -1;
+ freqs[ind2] *= -1;
+ nvals++;
+ }
+ nvals = nvals/2+1;
+
+ for (i = 0; i < nvals; i++) {
+ int code_len = 0;
+ for (k = codes[i]; k; k = codes[k])
+ code_len++;
+ codes[i] = code_len;
+ freqs[i] *= -1;
+ //fprintf(stderr, "%d / %d => %d\n", vals[i], freqs[i], codes[i]);
+ }
+
+ for (bits = i = 0; i < nvals; i++) {
+ bits += freqs[i] * codes[i];
+ }
+ if (fd->verbose > 1)
+ fprintf(stderr, "HUFFMAN = %d\n", bits);
+ if (best_size >= bits)
+ best_size = bits, best_encoding = E_HUFFMAN;
+ free(codes);
+
+ free(vals);
+ free(freqs);
+
+ return best_encoding;
+}
+
+void cram_stats_free(cram_stats *st) {
+ if (st->h)
+ kh_destroy(m_i2i, st->h);
+ free(st);
+}
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _CRAM_STATS_H_
+#define _CRAM_STATS_H_
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+cram_stats *cram_stats_create(void);
+void cram_stats_add(cram_stats *st, int32_t val);
+void cram_stats_del(cram_stats *st, int32_t val);
+void cram_stats_dump(cram_stats *st);
+void cram_stats_free(cram_stats *st);
+
+/*
+ * Computes entropy from integer frequencies for various encoding methods and
+ * picks the best encoding.
+ *
+ * FIXME: we could reuse some of the code here for the actual encoding
+ * parameters too. Eg the best 'k' for SUBEXP or the code lengths for huffman.
+ *
+ * Returns the best codec to use.
+ */
+enum cram_encoding cram_stats_encoding(cram_fd *fd, cram_stats *st);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/*
+Copyright (c) 2012-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _CRAM_STRUCTS_H_
+#define _CRAM_STRUCTS_H_
+
+/*
+ * Defines in-memory structs for the basic file-format objects in the
+ * CRAM format.
+ *
+ * The basic file format is:
+ * File-def SAM-hdr Container Container ...
+ *
+ * Container:
+ * Service-block data-block data-block ...
+ *
+ * Multiple blocks in a container are grouped together as slices,
+ * also sometimes referred to as landmarks in the spec.
+ */
+
+
+#include <stdint.h>
+
+#include "cram/thread_pool.h"
+#include "cram/string_alloc.h"
+#include "cram/mFILE.h"
+#include "htslib/khash.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+// Generic hash-map integer -> integer
+KHASH_MAP_INIT_INT(m_i2i, int)
+
+// Generic hash-set integer -> (existance)
+KHASH_SET_INIT_INT(s_i2i)
+
+// For brevity
+typedef unsigned char uc;
+
+/*
+ * A union for the preservation map. Required for khash.
+ */
+typedef union {
+ int i;
+ char *p;
+} pmap_t;
+
+// Generates static functions here which isn't ideal, but we have no way
+// currently to declare the kh_map_t structure here without also declaring a
+// duplicate in the .c files due to the nature of the KHASH macros.
+KHASH_MAP_INIT_STR(map, pmap_t)
+
+struct hFILE;
+
+#define SEQS_PER_SLICE 10000
+#define SLICE_PER_CNT 1
+
+#define CRAM_SUBST_MATRIX "CGTNAGTNACTNACGNACGT"
+
+#define MAX_STAT_VAL 1024
+//#define MAX_STAT_VAL 16
+typedef struct cram_stats {
+ int freqs[MAX_STAT_VAL];
+ khash_t(m_i2i) *h;
+ int nsamp; // total number of values added
+ int nvals; // total number of unique values added
+} cram_stats;
+
+/* NB: matches java impl, not the spec */
+enum cram_encoding {
+ E_NULL = 0,
+ E_EXTERNAL = 1,
+ E_GOLOMB = 2,
+ E_HUFFMAN = 3,
+ E_BYTE_ARRAY_LEN = 4,
+ E_BYTE_ARRAY_STOP = 5,
+ E_BETA = 6,
+ E_SUBEXP = 7,
+ E_GOLOMB_RICE = 8,
+ E_GAMMA = 9,
+ E_NUM_CODECS = 10, /* Number of codecs, not a real one. */
+};
+
+enum cram_external_type {
+ E_INT = 1,
+ E_LONG = 2,
+ E_BYTE = 3,
+ E_BYTE_ARRAY = 4,
+ E_BYTE_ARRAY_BLOCK = 5,
+};
+
+/* External IDs used by this implementation (only assumed during writing) */
+enum cram_DS_ID {
+ DS_CORE = 0,
+ DS_aux = 1, // aux_blk
+ DS_aux_OQ = 2,
+ DS_aux_BQ = 3,
+ DS_aux_BD = 4,
+ DS_aux_BI = 5,
+ DS_aux_FZ = 6, // also ZM:B
+ DS_aux_oq = 7, // other qualities
+ DS_aux_os = 8, // other sequences
+ DS_aux_oz = 9, // other strings
+ DS_ref,
+ DS_RN, // name_blk
+ DS_QS, // qual_blk
+ DS_IN, // base_blk
+ DS_SC, // soft_blk
+
+ DS_BF, // start loop
+ DS_CF,
+ DS_AP,
+ DS_RG,
+ DS_MQ,
+ DS_NS,
+ DS_MF,
+ DS_TS,
+ DS_NP,
+ DS_NF,
+ DS_RL,
+ DS_FN,
+ DS_FC,
+ DS_FP,
+ DS_DL,
+ DS_BA,
+ DS_BS,
+ DS_TL,
+ DS_RI,
+ DS_RS,
+ DS_PD,
+ DS_HC,
+ DS_BB,
+ DS_QQ,
+
+ DS_TN, // end loop
+
+ DS_RN_len,
+ DS_SC_len,
+ DS_BB_len,
+ DS_QQ_len,
+
+ DS_TC, // CRAM v1.0 tags
+ DS_TM, // test
+ DS_TV, // test
+
+ DS_END,
+};
+
+/* "File Definition Structure" */
+typedef struct cram_file_def {
+ char magic[4];
+ uint8_t major_version;
+ uint8_t minor_version;
+ char file_id[20]; // Filename or SHA1 checksum
+} cram_file_def;
+
+#define CRAM_MAJOR_VERS(v) ((v) >> 8)
+#define CRAM_MINOR_VERS(v) ((v) & 0xff)
+
+struct cram_slice;
+
+enum cram_block_method {
+ ERROR = -1,
+ RAW = 0,
+ GZIP = 1,
+ BZIP2 = 2,
+ LZMA = 3,
+ RANS = 4, // Generic; either order
+ RANS0 = 4,
+ RANS1 = 10, // Not externalised; stored as RANS (generic)
+ GZIP_RLE = 11, // NB: not externalised in CRAM
+};
+
+enum cram_content_type {
+ CT_ERROR = -1,
+ FILE_HEADER = 0,
+ COMPRESSION_HEADER = 1,
+ MAPPED_SLICE = 2,
+ UNMAPPED_SLICE = 3, // CRAM V1.0 only
+ EXTERNAL = 4,
+ CORE = 5,
+};
+
+/* Compression metrics */
+typedef struct {
+ // number of trials and time to next trial
+ int trial;
+ int next_trial;
+
+ // aggregate sizes during trials
+ int sz_gz_rle;
+ int sz_gz_def;
+ int sz_rans0;
+ int sz_rans1;
+ int sz_bzip2;
+ int sz_lzma;
+
+ // resultant method from trials
+ int method;
+ int strat;
+
+ // Revisions of method, to allow culling of continually failing ones.
+ int gz_rle_cnt;
+ int gz_def_cnt;
+ int rans0_cnt;
+ int rans1_cnt;
+ int bzip2_cnt;
+ int lzma_cnt;
+ int revised_method;
+
+ double gz_rle_extra;
+ double gz_def_extra;
+ double rans0_extra;
+ double rans1_extra;
+ double bzip2_extra;
+ double lzma_extra;
+} cram_metrics;
+
+/* Block */
+typedef struct cram_block {
+ enum cram_block_method method, orig_method;
+ enum cram_content_type content_type;
+ int32_t content_id;
+ int32_t comp_size;
+ int32_t uncomp_size;
+ uint32_t crc32;
+ int32_t idx; /* offset into data */
+ unsigned char *data;
+
+ // For bit I/O
+ size_t alloc;
+ size_t byte;
+ int bit;
+} cram_block;
+
+struct cram_codec; /* defined in cram_codecs.h */
+struct cram_map;
+
+#define CRAM_MAP_HASH 32
+#define CRAM_MAP(a,b) (((a)*3+(b))&(CRAM_MAP_HASH-1))
+
+/* Compression header block */
+typedef struct cram_block_compression_hdr {
+ int32_t ref_seq_id;
+ int32_t ref_seq_start;
+ int32_t ref_seq_span;
+ int32_t num_records;
+ int32_t num_landmarks;
+ int32_t *landmark;
+
+ /* Flags from preservation map */
+ int mapped_qs_included;
+ int unmapped_qs_included;
+ int unmapped_placed;
+ int qs_included;
+ int read_names_included;
+ int AP_delta;
+ // indexed by ref-base and subst. code
+ char substitution_matrix[5][4];
+
+ // TD Dictionary as a concatenated block
+ cram_block *TD_blk; // Tag Dictionary
+ int nTL; // number of TL entries in TD
+ unsigned char **TL; // array of size nTL, pointer into TD_blk.
+ khash_t(m_s2i) *TD_hash; // Keyed on TD strings, map to TL[] indices
+ string_alloc_t *TD_keys; // Pooled keys for TD hash.
+
+ khash_t(map) *preservation_map;
+ struct cram_map *rec_encoding_map[CRAM_MAP_HASH];
+ struct cram_map *tag_encoding_map[CRAM_MAP_HASH];
+
+ struct cram_codec *codecs[DS_END];
+
+ char *uncomp; // A single block of uncompressed data
+ size_t uncomp_size, uncomp_alloc;
+
+ unsigned int data_series; // See cram_fields enum below
+} cram_block_compression_hdr;
+
+typedef struct cram_map {
+ int key; /* 0xe0 + 3 bytes */
+ enum cram_encoding encoding;
+ int offset; /* Offset into a single block of memory */
+ int size; /* Size */
+ struct cram_codec *codec;
+ struct cram_map *next; // for noddy internal hash
+} cram_map;
+
+/* Mapped or unmapped slice header block */
+typedef struct cram_block_slice_hdr {
+ enum cram_content_type content_type;
+ int32_t ref_seq_id; /* if content_type == MAPPED_SLICE */
+ int32_t ref_seq_start; /* if content_type == MAPPED_SLICE */
+ int32_t ref_seq_span; /* if content_type == MAPPED_SLICE */
+ int32_t num_records;
+ int64_t record_counter;
+ int32_t num_blocks;
+ int32_t num_content_ids;
+ int32_t *block_content_ids;
+ int32_t ref_base_id; /* if content_type == MAPPED_SLICE */
+ unsigned char md5[16];
+} cram_block_slice_hdr;
+
+struct ref_entry;
+
+/*
+ * Container.
+ *
+ * Conceptually a container is split into slices, and slices into blocks.
+ * However on disk it's just a list of blocks and we need to query the
+ * block types to identify the start/end points of the slices.
+ *
+ * OR... are landmarks the start/end points of slices?
+ */
+typedef struct cram_container {
+ int32_t length;
+ int32_t ref_seq_id;
+ int32_t ref_seq_start;
+ int32_t ref_seq_span;
+ int64_t record_counter;
+ int64_t num_bases;
+ int32_t num_records;
+ int32_t num_blocks;
+ int32_t num_landmarks;
+ int32_t *landmark;
+
+ /* Size of container header above */
+ size_t offset;
+
+ /* Compression header is always the first block? */
+ cram_block_compression_hdr *comp_hdr;
+ cram_block *comp_hdr_block;
+
+ /* For construction purposes */
+ int max_slice, curr_slice; // maximum number of slices
+ int max_rec, curr_rec; // current and max recs per slice
+ int max_c_rec, curr_c_rec; // current and max recs per container
+ int slice_rec; // rec no. for start of this slice
+ int curr_ref; // current ref ID. -2 for no previous
+ int last_pos; // last record position
+ struct cram_slice **slices, *slice;
+ int pos_sorted; // boolean, 1=>position sorted data
+ int max_apos; // maximum position, used if pos_sorted==0
+ int last_slice; // number of reads in last slice (0 for 1st)
+ int multi_seq; // true if packing multi seqs per cont/slice
+ int unsorted; // true is AP_delta is 0.
+
+ /* Copied from fd before encoding, to allow multi-threading */
+ int ref_start, first_base, last_base, ref_id, ref_end;
+ char *ref;
+ //struct ref_entry *ref;
+
+ /* For multi-threading */
+ bam_seq_t **bams;
+
+ /* Statistics for encoding */
+ cram_stats *stats[DS_END];
+
+ khash_t(s_i2i) *tags_used; // set of tag types in use, for tag encoding map
+ int *refs_used; // array of frequency of ref seq IDs
+
+ uint32_t crc32; // CRC32
+} cram_container;
+
+/*
+ * A single cram record
+ */
+typedef struct cram_record {
+ struct cram_slice *s; // Filled out by cram_decode only
+
+ int32_t ref_id; // fixed for all recs in slice?
+ int32_t flags; // BF
+ int32_t cram_flags; // CF
+ int32_t len; // RL
+ int32_t apos; // AP
+ int32_t rg; // RG
+ int32_t name; // RN; idx to s->names_blk
+ int32_t name_len;
+ int32_t mate_line; // index to another cram_record
+ int32_t mate_ref_id;
+ int32_t mate_pos; // NP
+ int32_t tlen; // TS
+
+ // Auxiliary data
+ int32_t ntags; // TC
+ int32_t aux; // idx to s->aux_blk
+ int32_t aux_size; // total size of packed ntags in aux_blk
+#ifndef TN_external
+ int32_t TN_idx; // TN; idx to s->TN;
+#else
+ int32_t tn; // idx to s->tn_blk
+#endif
+ int TL;
+
+ int32_t seq; // idx to s->seqs_blk
+ int32_t qual; // idx to s->qual_blk
+ int32_t cigar; // idx to s->cigar
+ int32_t ncigar;
+ int32_t aend; // alignment end
+ int32_t mqual; // MQ
+
+ int32_t feature; // idx to s->feature
+ int32_t nfeature; // number of features
+ int32_t mate_flags; // MF
+} cram_record;
+
+// Accessor macros as an analogue of the bam ones
+#define cram_qname(c) (&(c)->s->name_blk->data[(c)->name])
+#define cram_seq(c) (&(c)->s->seqs_blk->data[(c)->seq])
+#define cram_qual(c) (&(c)->s->qual_blk->data[(c)->qual])
+#define cram_aux(c) (&(c)->s->aux_blk->data[(c)->aux])
+#define cram_seqi(c,i) (cram_seq((c))[(i)])
+#define cram_name_len(c) ((c)->name_len)
+#define cram_strand(c) (((c)->flags & BAM_FREVERSE) != 0)
+#define cram_mstrand(c) (((c)->flags & BAM_FMREVERSE) != 0)
+#define cram_cigar(c) (&((cr)->s->cigar)[(c)->cigar])
+
+/*
+ * A feature is a base difference, used for the sequence reference encoding.
+ * (We generate these internally when writing CRAM.)
+ */
+typedef struct cram_feature {
+ union {
+ struct {
+ int pos;
+ int code;
+ int base; // substitution code
+ } X;
+ struct {
+ int pos;
+ int code;
+ int base; // actual base & qual
+ int qual;
+ } B;
+ struct {
+ int pos;
+ int code;
+ int seq_idx; // index to s->seqs_blk
+ int len;
+ } b;
+ struct {
+ int pos;
+ int code;
+ int qual;
+ } Q;
+ struct {
+ int pos;
+ int code;
+ int len;
+ int seq_idx; // soft-clip multiple bases
+ } S;
+ struct {
+ int pos;
+ int code;
+ int len;
+ int seq_idx; // insertion multiple bases
+ } I;
+ struct {
+ int pos;
+ int code;
+ int base; // insertion single base
+ } i;
+ struct {
+ int pos;
+ int code;
+ int len;
+ } D;
+ struct {
+ int pos;
+ int code;
+ int len;
+ } N;
+ struct {
+ int pos;
+ int code;
+ int len;
+ } P;
+ struct {
+ int pos;
+ int code;
+ int len;
+ } H;
+ };
+} cram_feature;
+
+/*
+ * A slice is really just a set of blocks, but it
+ * is the logical unit for decoding a number of
+ * sequences.
+ */
+typedef struct cram_slice {
+ cram_block_slice_hdr *hdr;
+ cram_block *hdr_block;
+ cram_block **block;
+ cram_block **block_by_id;
+
+ /* State used during encoding/decoding */
+ int last_apos, max_apos;
+
+ /* Array of decoded cram records */
+ cram_record *crecs;
+
+ /* An dynamically growing buffers for data pointed
+ * to by crecs[] array.
+ */
+ uint32_t *cigar;
+ uint32_t cigar_alloc;
+ uint32_t ncigar;
+
+ cram_feature *features;
+ int nfeatures;
+ int afeatures; // allocated size of features
+
+#ifndef TN_external
+ // TN field (Tag Name)
+ uint32_t *TN;
+ int nTN, aTN; // used and allocated size for TN[]
+#else
+ cram_block *tn_blk;
+ int tn_id;
+#endif
+
+ // For variable sized elements which are always external blocks.
+ cram_block *name_blk;
+ cram_block *seqs_blk;
+ cram_block *qual_blk;
+ cram_block *base_blk;
+ cram_block *soft_blk;
+ cram_block *aux_blk;
+ cram_block *aux_OQ_blk;
+ cram_block *aux_BQ_blk;
+ cram_block *aux_BD_blk;
+ cram_block *aux_BI_blk;
+ cram_block *aux_FZ_blk;
+ cram_block *aux_oq_blk;
+ cram_block *aux_os_blk;
+ cram_block *aux_oz_blk;
+
+ string_alloc_t *pair_keys; // Pooled keys for pair hash.
+ khash_t(m_s2i) *pair[2]; // for identifying read-pairs in this slice.
+
+ char *ref; // slice of current reference
+ int ref_start; // start position of current reference;
+ int ref_end; // end position of current reference;
+ int ref_id;
+} cram_slice;
+
+/*-----------------------------------------------------------------------------
+ * Consider moving reference handling to cram_refs.[ch]
+ */
+// from fa.fai / samtools faidx files
+typedef struct ref_entry {
+ char *name;
+ char *fn;
+ int64_t length;
+ int64_t offset;
+ int bases_per_line;
+ int line_length;
+ int64_t count; // for shared references so we know to dealloc seq
+ char *seq;
+ mFILE *mf;
+ int is_md5; // Reference comes from a raw seq found by MD5
+} ref_entry;
+
+KHASH_MAP_INIT_STR(refs, ref_entry*)
+
+// References structure.
+typedef struct {
+ string_alloc_t *pool; // String pool for holding filenames and SN vals
+
+ khash_t(refs) *h_meta; // ref_entry*, index by name
+ ref_entry **ref_id; // ref_entry*, index by ID
+ int nref; // number of ref_entry
+
+ char *fn; // current file opened
+ BGZF *fp; // and the hFILE* to go with it.
+
+ int count; // how many cram_fd sharing this refs struct
+
+ pthread_mutex_t lock; // Mutex for multi-threaded updating
+ ref_entry *last; // Last queried sequence
+ int last_id; // Used in cram_ref_decr_locked to delay free
+} refs_t;
+
+/*-----------------------------------------------------------------------------
+ * CRAM index
+ *
+ * Detect format by number of entries per line.
+ * 5 => 1.0 (refid, start, nseq, C offset, slice)
+ * 6 => 1.1 (refid, start, span, C offset, S offset, S size)
+ *
+ * Indices are stored in a nested containment list, which is trivial to set
+ * up as the indices are on sorted data so we're appending to the nclist
+ * in sorted order. Basically if a slice entirely fits within a previous
+ * slice then we append to that slices list. This is done recursively.
+ *
+ * Lists are sorted on two dimensions: ref id + slice coords.
+ */
+typedef struct cram_index {
+ int nslice, nalloc; // total number of slices
+ struct cram_index *e; // array of size nslice
+
+ int refid; // 1.0 1.1
+ int start; // 1.0 1.1
+ int end; // 1.1
+ int nseq; // 1.0 - undocumented
+ int slice; // 1.0 landmark index, 1.1 landmark value
+ int len; // 1.1 - size of slice in bytes
+ int64_t offset; // 1.0 1.1
+} cram_index;
+
+typedef struct {
+ int refid;
+ int start;
+ int end;
+} cram_range;
+
+/*-----------------------------------------------------------------------------
+ */
+/* CRAM File handle */
+
+typedef struct spare_bams {
+ bam_seq_t **bams;
+ struct spare_bams *next;
+} spare_bams;
+
+typedef struct cram_fd {
+ struct hFILE *fp;
+ int mode; // 'r' or 'w'
+ int version;
+ cram_file_def *file_def;
+ SAM_hdr *header;
+
+ char *prefix;
+ int64_t record_counter;
+ int err;
+
+ // Most recent compression header decoded
+ //cram_block_compression_hdr *comp_hdr;
+ //cram_block_slice_hdr *slice_hdr;
+
+ // Current container being processed.
+ cram_container *ctr;
+
+ // positions for encoding or decoding
+ int first_base, last_base;
+
+ // cached reference portion
+ refs_t *refs; // ref meta-data structure
+ char *ref, *ref_free; // current portion held in memory
+ int ref_id;
+ int ref_start;
+ int ref_end;
+ char *ref_fn; // reference fasta filename
+
+ // compression level and metrics
+ int level;
+ cram_metrics *m[DS_END];
+
+ // options
+ int decode_md; // Whether to export MD and NM tags
+ int verbose;
+ int seqs_per_slice;
+ int slices_per_container;
+ int embed_ref;
+ int no_ref;
+ int ignore_md5;
+ int use_bz2;
+ int use_rans;
+ int use_lzma;
+ int shared_ref;
+ unsigned int required_fields;
+ cram_range range;
+
+ // lookup tables, stored here so we can be trivially multi-threaded
+ unsigned int bam_flag_swap[0x1000]; // cram -> bam flags
+ unsigned int cram_flag_swap[0x1000];// bam -> cram flags
+ unsigned char L1[256]; // ACGT{*} ->0123{4}
+ unsigned char L2[256]; // ACGTN{*}->01234{5}
+ char cram_sub_matrix[32][32]; // base substituion codes
+
+ int index_sz;
+ cram_index *index; // array, sizeof index_sz
+ off_t first_container;
+ int eof;
+ int last_slice; // number of recs encoded in last slice
+ int multi_seq;
+ int unsorted;
+ int empty_container; // Marker for EOF block
+
+ // thread pool
+ int own_pool;
+ t_pool *pool;
+ t_results_queue *rqueue;
+ pthread_mutex_t metrics_lock;
+ pthread_mutex_t ref_lock;
+ spare_bams *bl;
+ pthread_mutex_t bam_list_lock;
+ void *job_pending;
+ int ooc; // out of containers.
+} cram_fd;
+
+// Translation of required fields to cram data series
+enum cram_fields {
+ CRAM_BF = 0x00000001,
+ CRAM_AP = 0x00000002,
+ CRAM_FP = 0x00000004,
+ CRAM_RL = 0x00000008,
+ CRAM_DL = 0x00000010,
+ CRAM_NF = 0x00000020,
+ CRAM_BA = 0x00000040,
+ CRAM_QS = 0x00000080,
+ CRAM_FC = 0x00000100,
+ CRAM_FN = 0x00000200,
+ CRAM_BS = 0x00000400,
+ CRAM_IN = 0x00000800,
+ CRAM_RG = 0x00001000,
+ CRAM_MQ = 0x00002000,
+ CRAM_TL = 0x00004000,
+ CRAM_RN = 0x00008000,
+ CRAM_NS = 0x00010000,
+ CRAM_NP = 0x00020000,
+ CRAM_TS = 0x00040000,
+ CRAM_MF = 0x00080000,
+ CRAM_CF = 0x00100000,
+ CRAM_RI = 0x00200000,
+ CRAM_RS = 0x00400000,
+ CRAM_PD = 0x00800000,
+ CRAM_HC = 0x01000000,
+ CRAM_SC = 0x02000000,
+ CRAM_BB = 0x04000000,
+ CRAM_BB_len = 0x08000000,
+ CRAM_QQ = 0x10000000,
+ CRAM_QQ_len = 0x20000000,
+ CRAM_aux= 0x40000000,
+ CRAM_ALL= 0x7fffffff,
+};
+
+// A CIGAR opcode, but not necessarily the implications of it. Eg FC/FP may
+// encode a base difference, but we don't need to know what it is for CIGAR.
+// If we have a soft-clip or insertion, we do need SC/IN though to know how
+// long that array is.
+#define CRAM_CIGAR (CRAM_FN | CRAM_FP | CRAM_FC | CRAM_DL | CRAM_IN | \
+ CRAM_SC | CRAM_HC | CRAM_PD | CRAM_RS | CRAM_RL | CRAM_BF)
+
+#define CRAM_SEQ (CRAM_CIGAR | CRAM_BA | CRAM_BS | \
+ CRAM_RL | CRAM_AP | CRAM_BB)
+
+#define CRAM_QUAL (CRAM_CIGAR | CRAM_RL | CRAM_AP | CRAM_QS | CRAM_QQ)
+
+/* BF bitfields */
+/* Corrected in 1.1. Use bam_flag_swap[bf] and BAM_* macros for 1.0 & 1.1 */
+#define CRAM_FPAIRED 256
+#define CRAM_FPROPER_PAIR 128
+#define CRAM_FUNMAP 64
+#define CRAM_FREVERSE 32
+#define CRAM_FREAD1 16
+#define CRAM_FREAD2 8
+#define CRAM_FSECONDARY 4
+#define CRAM_FQCFAIL 2
+#define CRAM_FDUP 1
+
+#define DS_aux_S "\001"
+#define DS_aux_OQ_S "\002"
+#define DS_aux_BQ_S "\003"
+#define DS_aux_BD_S "\004"
+#define DS_aux_BI_S "\005"
+#define DS_aux_FZ_S "\006"
+#define DS_aux_oq_S "\007"
+#define DS_aux_os_S "\010"
+#define DS_aux_oz_S "\011"
+
+#define CRAM_M_REVERSE 1
+#define CRAM_M_UNMAP 2
+
+
+/* CF bitfields */
+#define CRAM_FLAG_PRESERVE_QUAL_SCORES (1<<0)
+#define CRAM_FLAG_DETACHED (1<<1)
+#define CRAM_FLAG_MATE_DOWNSTREAM (1<<2)
+#define CRAM_FLAG_NO_SEQ (1<<3)
+#define CRAM_FLAG_MASK ((1<<4)-1)
+
+/* Internal only */
+#define CRAM_FLAG_STATS_ADDED (1<<30)
+
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _CRAM_STRUCTS_H_ */
--- /dev/null
+/*
+Copyright (c) 1994, 1996-1997, 2000, 2003 MEDICAL RESEARCH COUNCIL
+All rights reserved
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1 Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2 Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3 Neither the name of the MEDICAL RESEARCH COUNCIL, THE LABORATORY OF
+MOLECULAR BIOLOGY nor the names of its contributors may be used to endorse or
+promote products derived from this software without specific prior written
+permission.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR
+ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
+(INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
+LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON
+ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+(INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
+SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+ */
+
+#include <config.h>
+
+#include "cram/misc.h"
+
+#include <sys/types.h>
+#include <sys/stat.h>
+/* Alliant's Concentrix <sys/stat.h> is hugely deficient */
+/* Define things we require in this program */
+/* Methinks S_IFMT and S_IFDIR aren't defined in POSIX */
+#ifndef S_ISDIR
+#define S_ISDIR(m) (((m)&S_IFMT) == S_IFDIR)
+#endif /*!S_ISDIR*/
+#ifndef S_ISREG
+#define S_ISREG(m) (((m)&S_IFMT) == S_IFREG)
+#endif /*!S_ISREG*/
+
+int is_directory(char * fn)
+{
+ struct stat buf;
+ if ( stat(fn,&buf) ) return 0;
+ return S_ISDIR(buf.st_mode);
+}
+
+int is_file(char * fn)
+{
+ struct stat buf;
+ if ( stat(fn,&buf) ) return 0;
+ return S_ISREG(buf.st_mode);
+}
+
+int file_exists(char * fn)
+{
+ struct stat buf;
+ return ( stat(fn,&buf) == 0);
+}
+
+int file_size(char * fn)
+{
+ struct stat buf;
+ if ( stat(fn,&buf) != 0) return 0;
+ return buf.st_size;
+}
+
--- /dev/null
+/*
+Copyright (c) 2005-2006, 2008-2009, 2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <stdio.h>
+#include <stdlib.h>
+#include <errno.h>
+#include <string.h>
+#include <sys/types.h>
+#include <sys/stat.h>
+#include <fcntl.h>
+#include <unistd.h>
+#include <stdarg.h>
+
+#include "cram/os.h"
+#include "cram/mFILE.h"
+#include "cram/vlen.h"
+
+#ifdef HAVE_MMAP
+#include <sys/mman.h>
+#endif
+
+/*
+ * This file contains memory-based versions of the most commonly used
+ * (by io_lib) stdio functions.
+ *
+ * Actual file IO takes place either on opening or closing an mFILE.
+ *
+ * Coupled to this are a bunch of rather scary macros which can be obtained
+ * by including stdio_hack.h. It is recommended though that you use mFILE.h
+ * instead and replace fopen with mfopen (etc). This is more or less
+ * mandatory if you wish to use both FILE and mFILE structs in a single file.
+ */
+
+static mFILE *m_channel[3]; /* stdin, stdout and stderr fakes */
+
+/*
+ * Reads the entirety of fp into memory. If 'fn' exists it is the filename
+ * associated with fp. This will be used for more optimal reading (via a
+ * stat to identify the size and a single read). Otherwise we use successive
+ * reads until EOF.
+ *
+ * Returns a malloced buffer on success of length *size
+ * NULL on failure
+ */
+static char *mfload(FILE *fp, const char *fn, size_t *size, int binary) {
+ struct stat sb;
+ char *data = NULL;
+ size_t allocated = 0, used = 0;
+ int bufsize = 8192;
+
+#ifdef _WIN32
+ if (binary)
+ _setmode(_fileno(fp), _O_BINARY);
+ else
+ _setmode(_fileno(fp), _O_TEXT);
+#endif
+
+ if (fn && -1 != stat(fn, &sb)) {
+ data = malloc(allocated = sb.st_size);
+ bufsize = sb.st_size;
+ } else {
+ fn = NULL;
+ }
+
+ do {
+ size_t len;
+ if (used + bufsize > allocated) {
+ allocated += bufsize;
+ data = realloc(data, allocated);
+ }
+ len = fread(data + used, 1, allocated - used, fp);
+ if (len > 0)
+ used += len;
+ } while (!feof(fp) && (fn == NULL || used < sb.st_size));
+
+ *size = used;
+
+ return data;
+}
+
+
+#ifdef HAVE_MMAP
+/*
+ * mmaps in the file, but only for reading currently.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int mfmmap(mFILE *mf, FILE *fp, const char *fn) {
+ struct stat sb;
+
+ if (stat(fn, &sb) != 0)
+ return -1;
+
+ mf->size = sb.st_size;
+ mf->data = mmap(NULL, mf->size, PROT_READ, MAP_SHARED,
+ fileno(fp), 0);
+
+ if (!mf->data)
+ return -1;
+
+ mf->alloced = 0;
+ return 0;
+}
+#endif
+
+
+/*
+ * Creates and returns m_channel[0].
+ * We initialise this on the first attempted read, which then slurps in
+ * all of stdin until EOF is met.
+ */
+mFILE *mstdin(void) {
+ if (m_channel[0])
+ return m_channel[0];
+
+ m_channel[0] = mfcreate(NULL, 0);
+ if (NULL == m_channel[0]) return NULL;
+ m_channel[0]->fp = stdin;
+ return m_channel[0];
+}
+
+static void init_mstdin(void) {
+ static int done_stdin = 0;
+ if (done_stdin)
+ return;
+
+ m_channel[0]->data = mfload(stdin, NULL, &m_channel[0]->size, 1);
+ m_channel[0]->mode = MF_READ;
+ done_stdin = 1;
+}
+
+/*
+ * Creates and returns m_channel[1]. This is the fake for stdout. It starts as
+ * an empty buffer which is physically written out only when mfflush or
+ * mfclose are called.
+ */
+mFILE *mstdout(void) {
+ if (m_channel[1])
+ return m_channel[1];
+
+ m_channel[1] = mfcreate(NULL, 0);
+ if (NULL == m_channel[1]) return NULL;
+ m_channel[1]->fp = stdout;
+ m_channel[1]->mode = MF_WRITE;
+ return m_channel[1];
+}
+
+/*
+ * Stderr as an mFILE.
+ * The code handles stderr by returning m_channel[2], but also checking
+ * for stderr in fprintf (the common usage of it) to auto-flush.
+ */
+mFILE *mstderr(void) {
+ if (m_channel[2])
+ return m_channel[2];
+
+ m_channel[2] = mfcreate(NULL, 0);
+ if (NULL == m_channel[2]) return NULL;
+ m_channel[2]->fp = stderr;
+ m_channel[2]->mode = MF_WRITE;
+ return m_channel[2];
+}
+
+
+/*
+ * For creating existing mFILE pointers directly from memory buffers.
+ */
+mFILE *mfcreate(char *data, int size) {
+ mFILE *mf = (mFILE *)malloc(sizeof(*mf));
+ if (NULL == mf) return NULL;
+ mf->fp = NULL;
+ mf->data = data;
+ mf->alloced = size;
+ mf->size = size;
+ mf->eof = 0;
+ mf->offset = 0;
+ mf->flush_pos = 0;
+ mf->mode = MF_READ | MF_WRITE;
+ return mf;
+}
+
+/*
+ * Recreate an existing mFILE to house new data/size.
+ * It also rewinds the file.
+ */
+void mfrecreate(mFILE *mf, char *data, int size) {
+ if (mf->data)
+ free(mf->data);
+ mf->data = data;
+ mf->size = size;
+ mf->alloced = size;
+ mf->eof = 0;
+ mf->offset = 0;
+ mf->flush_pos = 0;
+}
+
+
+/*
+ * Creates a new mFILE to contain the contents of the FILE pointer.
+ * This mFILE is purely for in-memory operations and has no links to the
+ * original FILE* it came from. It also doesn't close the FILE pointer.
+ * Consider using mfreopen() is you need different behaviour.
+ *
+ * Returns mFILE * on success
+ * NULL on failure.
+ */
+mFILE *mfcreate_from(const char *path, const char *mode_str, FILE *fp) {
+ mFILE *mf;
+
+ /* Open using mfreopen() */
+ if (NULL == (mf = mfreopen(path, mode_str, fp)))
+ return NULL;
+
+ /* Disassociate from the input stream */
+ mf->fp = NULL;
+
+ return mf;
+}
+
+/*
+ * Converts a FILE * to an mFILE *.
+ * Use this for wrapper functions to turn external prototypes requring
+ * FILE * as an argument into internal code using mFILE *.
+ */
+mFILE *mfreopen(const char *path, const char *mode_str, FILE *fp) {
+ mFILE *mf;
+ int r = 0, w = 0, a = 0, b = 0, x = 0, mode = 0;
+
+ /* Parse mode:
+ * r = read file contents (if truncated => don't read)
+ * w = write on close
+ * a = position at end of buffer
+ * x = position at same location as the original fp, don't seek on flush
+ * + = for update (read and write)
+ * m = mmap (read only)
+ */
+ if (strchr(mode_str, 'r'))
+ r = 1, mode |= MF_READ;
+ if (strchr(mode_str, 'w'))
+ w = 1, mode |= MF_WRITE | MF_TRUNC;
+ if (strchr(mode_str, 'a'))
+ w = a = 1, mode |= MF_WRITE | MF_APPEND;
+ if (strchr(mode_str, 'b'))
+ b = 1, mode |= MF_BINARY;
+ if (strchr(mode_str, 'x'))
+ x = 1;
+ if (strchr(mode_str, '+')) {
+ w = 1, mode |= MF_READ | MF_WRITE;
+ if (a)
+ r = 1;
+ }
+#ifdef HAVE_MMAP
+ if (strchr(mode_str, 'm'))
+ if (!w) mode |= MF_MMAP;
+#endif
+
+ if (r) {
+ mf = mfcreate(NULL, 0);
+ if (NULL == mf) return NULL;
+ if (!(mode & MF_TRUNC)) {
+#ifdef HAVE_MMAP
+ if (mode & MF_MMAP) {
+ if (mfmmap(mf, fp, path) == -1) {
+ mf->data = NULL;
+ mode &= ~MF_MMAP;
+ }
+ }
+#endif
+ if (!mf->data) {
+ mf->data = mfload(fp, path, &mf->size, b);
+ mf->alloced = mf->size;
+ if (!a)
+ fseek(fp, 0, SEEK_SET);
+ }
+ }
+ } else if (w) {
+ /* Write - initialise the data structures */
+ mf = mfcreate(NULL, 0);
+ if (NULL == mf) return NULL;
+ } else {
+ fprintf(stderr, "Must specify either r, w or a for mode\n");
+ return NULL;
+ }
+ mf->fp = fp;
+ mf->mode = mode;
+
+ if (x) {
+ mf->mode |= MF_MODEX;
+ }
+
+ if (a) {
+ mf->flush_pos = mf->size;
+ fseek(fp, 0, SEEK_END);
+ }
+
+ return mf;
+}
+
+/*
+ * Opens a file. If we have read access (r or a+) then it loads the entire
+ * file into memory. If We have write access then the pathname is stored.
+ * We do not actually write until an mfclose, which then checks this pathname.
+ */
+mFILE *mfopen(const char *path, const char *mode) {
+ FILE *fp;
+
+ if (NULL == (fp = fopen(path, mode)))
+ return NULL;
+ return mfreopen(path, mode, fp);
+}
+
+/*
+ * Closes an mFILE. If the filename is known (implying write access) then this
+ * also writes the data to disk.
+ *
+ * Stdout is handled by calling mfflush which writes to stdout if appropriate.
+ */
+int mfclose(mFILE *mf) {
+ if (!mf)
+ return -1;
+
+ mfflush(mf);
+
+#ifdef HAVE_MMAP
+ if ((mf->mode & MF_MMAP) && mf->data) {
+ /* Mmaped */
+ munmap(mf->data, mf->size);
+ mf->data = NULL;
+ }
+#endif
+
+ if (mf->fp)
+ fclose(mf->fp);
+
+ mfdestroy(mf);
+
+ return 0;
+}
+
+/*
+ * Closes the file pointer contained within the mFILE without destroying
+ * the in-memory data.
+ *
+ * Attempting to do this on an mmaped buffer is an error.
+ */
+int mfdetach(mFILE *mf) {
+ if (!mf)
+ return -1;
+
+ mfflush(mf);
+ if (mf->mode & MF_MMAP)
+ return -1;
+
+ if (mf->fp) {
+ fclose(mf->fp);
+ mf->fp = NULL;
+ }
+
+ return 0;
+}
+
+/*
+ * Destroys an mFILE structure but does not flush or close it
+ */
+int mfdestroy(mFILE *mf) {
+ if (!mf)
+ return -1;
+
+ if (mf->data)
+ free(mf->data);
+ free(mf);
+
+ return 0;
+}
+
+/*
+ * Steals that data out of an mFILE. The mFILE itself will be closed.
+ * It is up to the caller to free the stolen buffer. If size_out is
+ * not NULL, mf->size will be stored in it.
+ * This is more-or-less the opposite of mfcreate().
+ *
+ * Note, we cannot steal the allocated buffer from an mmaped mFILE.
+ */
+
+void *mfsteal(mFILE *mf, size_t *size_out) {
+ void *data;
+
+ if (!mf) return NULL;
+
+ data = mf->data;
+
+ if (NULL != size_out) *size_out = mf->size;
+
+ if (mfdetach(mf) != 0)
+ return NULL;
+
+ mf->data = NULL;
+ mfdestroy(mf);
+
+ return data;
+}
+
+/*
+ * Seek/tell functions. Nothing more than updating and reporting an
+ * in-memory index. NB we can seek on stdin or stdout even provided we
+ * haven't been flushing.
+ */
+int mfseek(mFILE *mf, long offset, int whence) {
+ switch (whence) {
+ case SEEK_SET:
+ mf->offset = offset;
+ break;
+ case SEEK_CUR:
+ mf->offset += offset;
+ break;
+ case SEEK_END:
+ mf->offset = mf->size + offset;
+ break;
+ default:
+ errno = EINVAL;
+ return -1;
+ }
+
+ mf->eof = 0;
+ return 0;
+}
+
+long mftell(mFILE *mf) {
+ return mf->offset;
+}
+
+void mrewind(mFILE *mf) {
+ mf->offset = 0;
+ mf->eof = 0;
+}
+
+/*
+ * mftruncate is not directly a translation of ftruncate as the latter
+ * takes a file descriptor instead of a FILE *. It performs the analogous
+ * role though.
+ *
+ * If offset is -1 then the file is truncated to be the current file
+ * offset.
+ */
+void mftruncate(mFILE *mf, long offset) {
+ mf->size = offset != -1 ? offset : mf->offset;
+ if (mf->offset > mf->size)
+ mf->offset = mf->size;
+}
+
+int mfeof(mFILE *mf) {
+ return mf->eof;
+}
+
+/*
+ * mFILE read/write functions. Basically these turn fread/fwrite syntax
+ * into memcpy statements, with appropriate memory handling for writing.
+ */
+size_t mfread(void *ptr, size_t size, size_t nmemb, mFILE *mf) {
+ size_t len;
+ char *cptr = (char *)ptr;
+
+ if (mf == m_channel[0]) init_mstdin();
+
+ if (mf->size <= mf->offset)
+ return 0;
+
+ len = size * nmemb <= mf->size - mf->offset
+ ? size * nmemb
+ : mf->size - mf->offset;
+ if (!size)
+ return 0;
+
+ memcpy(cptr, &mf->data[mf->offset], len);
+ mf->offset += len;
+
+ if (len != size * nmemb) {
+ mf->eof = 1;
+ }
+
+ return len / size;
+}
+
+size_t mfwrite(void *ptr, size_t size, size_t nmemb, mFILE *mf) {
+ if (!(mf->mode & MF_WRITE))
+ return 0;
+
+ /* Append mode => forced all writes to end of file */
+ if (mf->mode & MF_APPEND)
+ mf->offset = mf->size;
+
+ /* Make sure we have enough room */
+ while (size * nmemb + mf->offset > mf->alloced) {
+ size_t new_alloced = mf->alloced ? mf->alloced * 2 : 1024;
+ void * new_data = realloc(mf->data, new_alloced);
+ if (NULL == new_data) return 0;
+ mf->alloced = new_alloced;
+ mf->data = new_data;
+ }
+
+ /* Record where we need to reflush from */
+ if (mf->offset < mf->flush_pos)
+ mf->flush_pos = mf->offset;
+
+ /* Copy the data over */
+ memcpy(&mf->data[mf->offset], ptr, size * nmemb);
+ mf->offset += size * nmemb;
+ if (mf->size < mf->offset)
+ mf->size = mf->offset;
+
+ return nmemb;
+}
+
+int mfgetc(mFILE *mf) {
+ if (mf == m_channel[0]) init_mstdin();
+ if (mf->offset < mf->size) {
+ return (unsigned char)mf->data[mf->offset++];
+ }
+
+ mf->eof = 1;
+ return -1;
+}
+
+int mungetc(int c, mFILE *mf) {
+ if (mf->offset > 0) {
+ mf->data[--mf->offset] = c;
+ return c;
+ }
+
+ mf->eof = 1;
+ return -1;
+}
+
+char *mfgets(char *s, int size, mFILE *mf) {
+ int i;
+
+ if (mf == m_channel[0]) init_mstdin();
+ *s = 0;
+ for (i = 0; i < size-1;) {
+ if (mf->offset < mf->size) {
+ s[i] = mf->data[mf->offset++];
+ if (s[i++] == '\n')
+ break;
+ } else {
+ mf->eof = 1;
+ break;
+ }
+ }
+
+ s[i] = 0;
+ return i ? s : NULL;
+}
+
+/*
+ * Flushes an mFILE. If this is a real open of a file in write mode then
+ * mFILE->fp will be set. We then write out any new data in mFILE since the
+ * last flush. We cannot tell what may have been modified as we don't keep
+ * track of that, so we typically rewrite out the entire file contents between
+ * the last flush_pos and the end of file.
+ *
+ * For stderr/stdout we also reset the offsets so we cannot modify things
+ * we've already output.
+ */
+int mfflush(mFILE *mf) {
+ if (!mf->fp)
+ return 0;
+
+ /* FIXME: only do this when opened in write mode */
+ if (mf == m_channel[1] || mf == m_channel[2]) {
+ if (mf->flush_pos < mf->size) {
+ size_t bytes = mf->size - mf->flush_pos;
+ if (fwrite(mf->data + mf->flush_pos, 1, bytes, mf->fp) < bytes)
+ return -1;
+ if (0 != fflush(mf->fp))
+ return -1;
+ }
+
+ /* Stdout & stderr are non-seekable streams so throw away the data */
+ mf->offset = mf->size = mf->flush_pos = 0;
+ }
+
+ /* only flush when opened in write mode */
+ if (mf->mode & MF_WRITE) {
+ if (mf->flush_pos < mf->size) {
+ size_t bytes = mf->size - mf->flush_pos;
+ if (!(mf->mode & MF_MODEX)) {
+ fseek(mf->fp, mf->flush_pos, SEEK_SET);
+ }
+ if (fwrite(mf->data + mf->flush_pos, 1, bytes, mf->fp) < bytes)
+ return -1;
+ if (0 != fflush(mf->fp))
+ return -1;
+ }
+ if (ftell(mf->fp) != -1 &&
+ ftruncate(fileno(mf->fp), ftell(mf->fp)) == -1)
+ return -1;
+ mf->flush_pos = mf->size;
+ }
+
+ return 0;
+}
+
+/*
+ * A wrapper around vsprintf() to write to an mFILE. This also uses vflen() to
+ * estimate how many additional bytes of storage will be required for the
+ * vsprintf to work.
+ */
+int mfprintf(mFILE *mf, char *fmt, ...) {
+ int ret;
+ size_t est_length;
+ va_list args;
+
+ va_start(args, fmt);
+ est_length = vflen(fmt, args);
+ va_end(args);
+ while (est_length + mf->offset > mf->alloced) {
+ size_t new_alloced = mf->alloced ? mf->alloced * 2 : 1024;
+ void * new_data = realloc(mf->data, new_alloced);
+ if (NULL == new_data) return -1;
+ mf->alloced = new_alloced;
+ mf->data = new_data;
+ }
+
+ va_start(args, fmt);
+ ret = vsprintf(&mf->data[mf->offset], fmt, args);
+ va_end(args);
+
+ if (ret > 0) {
+ mf->offset += ret;
+ if (mf->size < mf->offset)
+ mf->size = mf->offset;
+ }
+
+ if (mf->fp == stderr) {
+ /* Auto-flush for stderr */
+ if (0 != mfflush(mf)) return -1;
+ }
+
+ return ret;
+}
+
+/*
+ * Converts an mFILE from binary to ascii mode by replacing all
+ * cr-nl with nl.
+ *
+ * Primarily used on windows when we've uncompressed a binary file which
+ * happens to be a text file (eg Experiment File). Previously we would have
+ * seeked back to the start and used _setmode(fileno(fp), _O_TEXT).
+ *
+ * Side effect: resets offset and flush_pos back to the start.
+ */
+void mfascii(mFILE *mf) {
+ size_t p1, p2;
+
+ for (p1 = p2 = 1; p1 < mf->size; p1++, p2++) {
+ if (mf->data[p1] == '\n' && mf->data[p1-1] == '\r') {
+ p2--; /* delete the \r */
+ }
+ mf->data[p2] = mf->data[p1];
+ }
+ mf->size = p2;
+
+ mf->offset = mf->flush_pos = 0;
+}
--- /dev/null
+/*
+Copyright (c) 2005-2006, 2008-2009 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _MFILE_H_
+#define _MFILE_H_
+
+#include <stdio.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+typedef struct {
+ FILE *fp;
+ char *data;
+ size_t alloced;
+ int eof;
+ int mode; /* open mode in MF_?? define bit pattern */
+ size_t size;
+ size_t offset;
+ size_t flush_pos;
+} mFILE;
+
+#define MF_READ 1
+#define MF_WRITE 2
+#define MF_APPEND 4
+#define MF_BINARY 8
+#define MF_TRUNC 16
+#define MF_MODEX 32
+#define MF_MMAP 64
+
+mFILE *mfreopen(const char *path, const char *mode, FILE *fp);
+mFILE *mfopen(const char *path, const char *mode);
+int mfdetach(mFILE *mf);
+int mfclose(mFILE *mf);
+int mfdestroy(mFILE *mf);
+int mfseek(mFILE *mf, long offset, int whence);
+long mftell(mFILE *mf);
+void mrewind(mFILE *mf);
+void mftruncate(mFILE *mf, long offset);
+int mfeof(mFILE *mf);
+size_t mfread(void *ptr, size_t size, size_t nmemb, mFILE *mf);
+size_t mfwrite(void *ptr, size_t size, size_t nmemb, mFILE *mf);
+int mfgetc(mFILE *mf);
+int mungetc(int c, mFILE *mf);
+mFILE *mfcreate(char *data, int size);
+mFILE *mfcreate_from(const char *path, const char *mode_str, FILE *fp);
+void mfrecreate(mFILE *mf, char *data, int size);
+void *mfsteal(mFILE *mf, size_t *size_out);
+char *mfgets(char *s, int size, mFILE *mf);
+int mfflush(mFILE *mf);
+int mfprintf(mFILE *mf, char *fmt, ...);
+mFILE *mstdin(void);
+mFILE *mstdout(void);
+mFILE *mstderr(void);
+void mfascii(mFILE *mf);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _MFILE_H_ */
--- /dev/null
+/*
+Copyright (c) 1994-1997, 2001-2002 MEDICAL RESEARCH COUNCIL
+All rights reserved
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1 Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2 Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3 Neither the name of the MEDICAL RESEARCH COUNCIL, THE LABORATORY OF
+MOLECULAR BIOLOGY nor the names of its contributors may be used to endorse or
+promote products derived from this software without specific prior written
+permission.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR
+ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
+(INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
+LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON
+ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+(INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
+SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+ */
+
+/*
+Copyright (c) 2003-2013 Genome Research Ltd.
+
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _misc_h
+#define _misc_h
+
+#include "cram/os.h"
+
+#include <stdio.h>
+#include <stdarg.h> /* varargs needed for v*printf() prototypes */
+#include <sys/types.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*
+ * This informs gcc that crash() doesn't return, so it doesn't need to
+ * concern itself that code paths going via crash could mean some variables
+ * being undefined and then issuing uninitialised variable warnings.
+ * This particularly affected convert.
+ */
+#ifdef __GNUC__
+# define __NORETURN__ __attribute__ ((__noreturn__))
+#else
+# define __NORETURN__
+#endif
+
+/*
+ * Used for printf style argument checking. We can request a function such
+ * as vTcl_SetResult does argument checking, avoiding bugs with using
+ * %d and passing in a 64-bit record.
+ */
+#ifdef __GNUC__
+# define __PRINTF_FORMAT__(a,b) __attribute__ ((format (printf, a, b)))
+#else
+# define __PRINTF_FORMAT__(a,b)
+#endif
+
+extern int is_directory(char * fn);
+extern int is_file(char * fn);
+extern int file_size(char * fn);
+
+#define MIN(A,B) ( ( (A) < (B) ) ? (A) : (B) )
+#define MAX(A,B) ( ( (A) > (B) ) ? (A) : (B) )
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /*_misc_h*/
--- /dev/null
+/*
+Author: James Bonfield
+
+Copyright (c) 2000-2001 MEDICAL RESEARCH COUNCIL
+All rights reserved
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the name of the MEDICAL RESEARCH COUNCIL, THE LABORATORY OF
+MOLECULAR BIOLOGY nor the names of its contributors may be used to endorse or
+promote products derived from this software without specific prior written
+permission.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR
+ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
+(INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
+LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON
+ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+(INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
+SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+Copyright (c) 2008, 2009, 2013, 2014 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <stdlib.h>
+#include <stdio.h>
+#include <string.h>
+#include <unistd.h>
+#include <ctype.h>
+#include <limits.h>
+#include <sys/types.h>
+#include <sys/stat.h>
+#include "cram/os.h"
+#ifndef PATH_MAX
+# define PATH_MAX 1024
+#endif
+
+#include "cram/open_trace_file.h"
+#include "cram/misc.h"
+#include "htslib/hfile.h"
+
+/*
+ * Tokenises the search path splitting on colons (unix) or semicolons
+ * (windows).
+ * We also explicitly add a "./" to the end of the search path
+ *
+ * Returns: A new search path with items separated by nul chars. Two nul
+ * chars in a row represent the end of the tokenised path.
+ * Returns NULL for a failure.
+ *
+ * The returned data has been malloced. It is up to the caller to free this
+ * memory.
+ */
+char *tokenise_search_path(char *searchpath) {
+ char *newsearch;
+ unsigned int i, j;
+ size_t len;
+#ifdef _WIN32
+ char path_sep = ';';
+#else
+ char path_sep = ':';
+#endif
+
+ if (!searchpath)
+ searchpath="";
+
+ newsearch = (char *)malloc((len = strlen(searchpath))+5);
+ if (!newsearch)
+ return NULL;
+
+ for (i = 0, j = 0; i < len; i++) {
+ /* "::" => ":". Used for escaping colons in http://foo */
+ if (i < len-1 && searchpath[i] == ':' && searchpath[i+1] == ':') {
+ newsearch[j++] = ':';
+ i++;
+ continue;
+ }
+
+ /* Handle http:// and ftp:// too without :: */
+ if (path_sep == ':') {
+ if ((i == 0 || (i > 0 && searchpath[i-1] == ':')) &&
+ (!strncmp(&searchpath[i], "http:", 5) ||
+ !strncmp(&searchpath[i], "ftp:", 4) ||
+ !strncmp(&searchpath[i], "|http:", 6) ||
+ !strncmp(&searchpath[i], "|ftp:", 5) ||
+ !strncmp(&searchpath[i], "URL=http:", 9) ||
+ !strncmp(&searchpath[i], "URL=ftp:", 8))) {
+ do {
+ newsearch[j++] = searchpath[i];
+ } while (i<len && searchpath[i++] != ':');
+ if (searchpath[i] == ':')
+ i++;
+ if (searchpath[i]=='/')
+ newsearch[j++] = searchpath[i++];
+ if (searchpath[i]=='/')
+ newsearch[j++] = searchpath[i++];
+ // Look for host:port
+ do {
+ newsearch[j++] = searchpath[i++];
+ } while (i<len && searchpath[i] != ':' && searchpath[i] != '/');
+ newsearch[j++] = searchpath[i++];
+ if (searchpath[i] == ':')
+ i++;
+ }
+ }
+
+ if (searchpath[i] == path_sep) {
+ /* Skip blank path components */
+ if (j && newsearch[j-1] != 0)
+ newsearch[j++] = 0;
+ } else {
+ newsearch[j++] = searchpath[i];
+ }
+ }
+
+ if (j)
+ newsearch[j++] = 0;
+ newsearch[j++] = '.';
+ newsearch[j++] = '/';
+ newsearch[j++] = 0;
+ newsearch[j++] = 0;
+
+ return newsearch;
+}
+
+mFILE *find_file_url(char *file, char *url) {
+ char buf[8192], *cp;
+ mFILE *mf = NULL;
+ int maxlen = 8190 - strlen(file), len;
+ hFILE *hf;
+
+ /* Expand %s for the trace name */
+ for (cp = buf; *url && cp - buf < maxlen; url++) {
+ if (*url == '%' && *(url+1) == 's') {
+ url++;
+ cp += strlen(strcpy(cp, file));
+ } else {
+ *cp++ = *url;
+ }
+ }
+ *cp++ = 0;
+
+ if (!(hf = hopen(buf, "r")))
+ return NULL;
+
+ if (NULL == (mf = mfcreate(NULL, 0)))
+ return NULL;
+ while ((len = hread(hf, buf, 8192)) > 0) {
+ if (mfwrite(buf, len, 1, mf) <= 0) {
+ hclose_abruptly(hf);
+ mfdestroy(mf);
+ return NULL;
+ }
+ }
+ if (hclose(hf) < 0 || len < 0) {
+ mfdestroy(mf);
+ return NULL;
+ }
+
+ mrewind(mf);
+ return mf;
+}
+
+/*
+ * Takes a dirname possibly including % rules and appends the filename
+ * to it.
+ *
+ * Returns expanded pathname or NULL for malloc failure.
+ */
+static char *expand_path(char *file, char *dirname) {
+ size_t len = strlen(dirname);
+ size_t lenf = strlen(file);
+ char *cp, *path;
+
+ path = malloc(len+lenf+2); // worst expansion DIR/FILE
+ if (!path)
+ return NULL;
+
+ if (dirname[len-1] == '/')
+ len--;
+
+ /* Special case for "./" or absolute filenames */
+ if (*file == '/' || (len==1 && *dirname == '.')) {
+ sprintf(path, "%s", file);
+ } else {
+ /* Handle %[0-9]*s expansions, if required */
+ char *path_end = path;
+ *path = 0;
+ while ((cp = strchr(dirname, '%'))) {
+ char *endp;
+ long l = strtol(cp+1, &endp, 10);
+ if (*endp != 's') {
+ strncpy(path_end, dirname, (endp+1)-dirname);
+ path_end += (endp+1)-dirname;
+ dirname = endp+1;
+ continue;
+ }
+
+ strncpy(path_end, dirname, cp-dirname);
+ path_end += cp-dirname;
+ if (l) {
+ strncpy(path_end, file, l);
+ path_end += MIN(strlen(file), l);
+ file += MIN(strlen(file), l);
+ } else {
+ strcpy(path_end, file);
+ path_end += strlen(file);
+ file += strlen(file);
+ }
+ len -= (endp+1) - dirname;
+ dirname = endp+1;
+ }
+ strncpy(path_end, dirname, len);
+ path_end += MIN(strlen(dirname), len);
+ *path_end = 0;
+ if (*file) {
+ *path_end++ = '/';
+ strcpy(path_end, file);
+ }
+ }
+
+ //fprintf(stderr, "*PATH=\"%s\"\n", path);
+ return path;
+}
+
+/*
+ * Searches for file in the directory 'dirname'. If it finds it, it opens
+ * it. This also searches for compressed versions of the file in dirname
+ * too.
+ *
+ * Returns mFILE pointer if found
+ * NULL if not
+ */
+static mFILE *find_file_dir(char *file, char *dirname) {
+ char *path;
+ mFILE *mf = NULL;
+
+ path = expand_path(file, dirname);
+
+ if (is_file(path))
+ mf = mfopen(path, "rbm");
+
+ free(path);
+ return mf;
+}
+
+/*
+ * ------------------------------------------------------------------------
+ * Public functions below.
+ */
+
+/*
+ * Opens a trace file named 'file'. This is initially looked for as a
+ * pathname relative to a file named "relative_to". This may (for
+ * example) be the name of an experiment file referencing the trace
+ * file. In this case by passing relative_to as the experiment file
+ * filename the trace file will be picked up in the same directory as
+ * the experiment file. Relative_to may be supplied as NULL.
+ *
+ * 'file' is looked for at relative_to, then the current directory, and then
+ * all of the locations listed in 'path' (which is a colon separated list).
+ * If 'path' is NULL it uses the RAWDATA environment variable instead.
+ *
+ * Returns a mFILE pointer when found.
+ * NULL otherwise.
+ */
+mFILE *open_path_mfile(char *file, char *path, char *relative_to) {
+ char *newsearch;
+ char *ele;
+ mFILE *fp;
+
+ /* Use path first */
+ if (!path)
+ path = getenv("RAWDATA");
+ if (NULL == (newsearch = tokenise_search_path(path)))
+ return NULL;
+
+ /*
+ * Step through the search path testing out each component.
+ * We now look through each path element treating some prefixes as
+ * special, otherwise we treat the element as a directory.
+ */
+ for (ele = newsearch; *ele; ele += strlen(ele)+1) {
+ char *ele2;
+
+ /*
+ * '|' prefixing a path component indicates that we do not
+ * wish to perform the compression extension searching in that
+ * location.
+ *
+ * NB: this has been removed from the htslib implementation.
+ */
+ if (*ele == '|') {
+ ele2 = ele+1;
+ } else {
+ ele2 = ele;
+ }
+
+ if (0 == strncmp(ele2, "URL=", 4)) {
+ if ((fp = find_file_url(file, ele2+4))) {
+ free(newsearch);
+ return fp;
+ }
+ } else if (!strncmp(ele2, "http:", 5) ||
+ !strncmp(ele2, "ftp:", 4)) {
+ if ((fp = find_file_url(file, ele2))) {
+ free(newsearch);
+ return fp;
+ }
+ } else if ((fp = find_file_dir(file, ele2))) {
+ free(newsearch);
+ return fp;
+ }
+ }
+
+ free(newsearch);
+
+ /* Look in the same location as the incoming 'relative_to' filename */
+ if (relative_to) {
+ char *cp;
+ char relative_path[PATH_MAX+1];
+ strcpy(relative_path, relative_to);
+ if ((cp = strrchr(relative_path, '/')))
+ *cp = 0;
+ if ((fp = find_file_dir(file, relative_path)))
+ return fp;
+ }
+
+ return NULL;
+}
+
+
+/*
+ * As per open_path_mfile, but searching only for local filenames.
+ * This is useful as we may avoid doing a full mfopen and loading
+ * the entire file into memory.
+ *
+ * Returns the expanded pathname if found.
+ * NULL if not
+ */
+char *find_path(char *file, char *path) {
+ char *newsearch;
+ char *ele;
+ char *outpath = NULL;
+
+ /* Use path first */
+ if (!path)
+ path = getenv("RAWDATA");
+ if (NULL == (newsearch = tokenise_search_path(path)))
+ return NULL;
+
+ for (ele = newsearch; *ele; ele += strlen(ele)+1) {
+ char *ele2 = (*ele == '|') ? ele+1 : ele;
+
+ if (!strncmp(ele2, "URL=", 4) ||
+ !strncmp(ele2, "http:", 5) ||
+ !strncmp(ele2, "ftp:", 4)) {
+ continue;
+ } else {
+ outpath = expand_path(file, ele2);
+ if (is_file(outpath)) {
+ free(newsearch);
+ return outpath;
+ } else {
+ free(outpath);
+ }
+ }
+ }
+
+ free(newsearch);
+
+ return NULL;
+}
--- /dev/null
+/*
+Author: James Bonfield
+
+Copyright (c) 2000-2001 MEDICAL RESEARCH COUNCIL
+All rights reserved
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ . Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ . Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ . Neither the name of the MEDICAL RESEARCH COUNCIL, THE LABORATORY OF
+MOLECULAR BIOLOGY nor the names of its contributors may be used to endorse or
+promote products derived from this software without specific prior written
+permission.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR
+ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
+(INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
+LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON
+ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+(INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
+SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+Copyright (c) 2008, 2009, 2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _OPEN_TRACE_FILE_H_
+#define _OPEN_TRACE_FILE_H_
+
+#include "cram/mFILE.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*
+ * Tokenises the search path splitting on colons (unix) or semicolons
+ * (windows).
+ * We also explicitly add a "./" to the end of the search path
+ *
+ * Returns: A new search path with items separated by nul chars. Two nul
+ * chars in a row represent the end of the tokenised path.
+ * Returns NULL for a failure.
+ *
+ * The returned data has been malloced. It is up to the caller to free this
+ * memory.
+ */
+char *tokenise_search_path(char *searchpath);
+
+/*
+ * Opens a trace file named 'file'. This is initially looked for as a
+ * pathname relative to a file named "relative_to". This may (for
+ * example) be the name of an experiment file referencing the trace
+ * file. In this case by passing relative_to as the experiment file
+ * filename the trace file will be picked up in the same directory as
+ * the experiment file. Relative_to may be supplied as NULL.
+ *
+ * 'file' is looked for at relative_to, then the current directory, and then
+ * all of the locations listed in 'path' (which is a colon separated list).
+ * If 'path' is NULL it uses the RAWDATA environment variable instead.
+ *
+ * Returns a mFILE pointer when found.
+ * NULL otherwise.
+ */
+mFILE *open_path_mfile(char *file, char *path, char *relative_to);
+
+/*
+ * Returns a mFILE containing the entire contents of the url;
+ * NULL on failure.
+ */
+mFILE *find_file_url(char *file, char *url);
+
+
+/*
+ * As per open_path_mfile, but searching only for local filenames.
+ * This is useful as we may avoid doing a full mfopen and loading
+ * the entire file into memory.
+ *
+ * Returns the expanded pathname if found.
+ * NULL if not
+ */
+char *find_path(char *file, char *path);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _OPEN_TRACE_FILE_H_ */
--- /dev/null
+/*
+Copyright (c) 1993, 1995-2002 MEDICAL RESEARCH COUNCIL
+All rights reserved
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1 Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2 Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3 Neither the name of the MEDICAL RESEARCH COUNCIL, THE LABORATORY OF
+MOLECULAR BIOLOGY nor the names of its contributors may be used to endorse or
+promote products derived from this software without specific prior written
+permission.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR
+ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
+(INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
+LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON
+ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+(INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
+SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+Copyright (c) 2004, 2006, 2009-2011, 2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+ * File: os.h
+ *
+ * Author:
+ * MRC Laboratory of Molecular Biology
+ * Hills Road
+ * Cambridge CB2 2QH
+ * United Kingdom
+ *
+ * Description: operating system specific type definitions
+ *
+ */
+
+#ifndef _OS_H_
+#define _OS_H_
+
+#include <limits.h>
+#include <inttypes.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*-----------------------------------------------------------------------------
+ * Detection of endianness. The main part of this is done in autoconf, but
+ * for the case of MacOS FAT binaries we fall back on auto-sensing based on
+ * processor type too.
+ */
+
+/* Set by autoconf */
+#define SP_LITTLE_ENDIAN
+
+/* Mac FAT binaries or unknown. Auto detect based on CPU type */
+#if !defined(SP_BIG_ENDIAN) && !defined(SP_LITTLE_ENDIAN)
+
+/*
+ * x86 equivalents
+ */
+#if defined(__i386__) || defined(__i386) || defined(__amd64__) || defined(__amd64) || defined(__x86_64__) || defined(__x86_64) || defined(__i686__) || defined(__i686)
+# if defined(SP_BIG_ENDIAN)
+# undef SP_BIG_ENDIAN
+# endif
+# define SP_LITTLE_ENDIAN
+#endif
+
+/*
+ * DEC Alpha
+ */
+#if defined(__alpha__) || defined(__alpha)
+# if defined(SP_LITTLE_ENDIAN)
+# undef SP_LITTLE_ENDIAN
+# endif
+# define SP_BIG_ENDIAN
+#endif
+
+/*
+ * SUN Sparc
+ */
+#if defined(__sparc__) || defined(__sparc)
+# if defined(SP_LITTLE_ENDIAN)
+# undef SP_LITTLE_ENDIAN
+# endif
+# define SP_BIG_ENDIAN
+#endif
+
+/*
+ * PowerPC
+ */
+#if defined(__ppc__) || defined(__ppc)
+# if defined(SP_LITTLE_ENDIAN)
+# undef SP_LITTLE_ENDIAN
+# endif
+# define SP_BIG_ENDIAN
+#endif
+
+/* Some catch-alls */
+#if defined(__LITTLE_ENDIAN__) || defined(__LITTLEENDIAN__)
+# define SP_LITTLE_ENDIAN
+#endif
+
+#if defined(__BIG_ENDIAN__) || defined(__BIGENDIAN__)
+# define SP_BIG_ENDIAN
+#endif
+
+#if defined(SP_BIG_ENDIAN) && defined(SP_LITTLE_ENDIAN)
+# error Both BIG and LITTLE endian defined. Fix os.h and/or Makefile
+#endif
+
+#if !defined(SP_BIG_ENDIAN) && !defined(SP_LITTLE_ENDIAN)
+# error Neither BIG nor LITTLE endian defined. Fix os.h and/or Makefile
+#endif
+
+#endif
+
+/*-----------------------------------------------------------------------------
+ * Allow for unaligned memory access. This is used in BAM code as the packed
+ * structure has 4-byte cigar ints after the variable length name.
+ *
+ * Consider using AX_CHECK_ALIGNED_ACCESS_REQUIRED in autoconf.
+ */
+#if defined(__i386__) || defined(__i386) || defined(__amd64__) || defined(__amd64) || defined(__x86_64__) || defined(__x86_64) || defined(__i686__) || defined(__i686)
+# define ALLOW_UAC
+#endif
+
+/*-----------------------------------------------------------------------------
+ * Byte swapping macros
+ */
+
+/*
+ * Our new swap runs at the same speed on Ultrix, but substantially faster
+ * (300% for swap_int4, ~50% for swap_int2) on an Alpha (due to the lack of
+ * decent 'char' support).
+ *
+ * They also have the ability to swap in situ (src == dst). Newer code now
+ * relies on this so don't change back!
+ */
+#define iswap_int8(x) \
+ (((x & 0x00000000000000ffLL) << 56) + \
+ ((x & 0x000000000000ff00LL) << 40) + \
+ ((x & 0x0000000000ff0000LL) << 24) + \
+ ((x & 0x00000000ff000000LL) << 8) + \
+ ((x & 0x000000ff00000000LL) >> 8) + \
+ ((x & 0x0000ff0000000000LL) >> 24) + \
+ ((x & 0x00ff000000000000LL) >> 40) + \
+ ((x & 0xff00000000000000LL) >> 56))
+
+#define iswap_int4(x) \
+ (((x & 0x000000ff) << 24) + \
+ ((x & 0x0000ff00) << 8) + \
+ ((x & 0x00ff0000) >> 8) + \
+ ((x & 0xff000000) >> 24))
+
+#define iswap_int2(x) \
+ (((x & 0x00ff) << 8) + \
+ ((x & 0xff00) >> 8))
+
+/*
+ * Linux systems may use byteswap.h to get assembly versions of byte-swap
+ * on intel systems. This can be as trivial as the bswap opcode, which works
+ * out at over 2-times faster than iswap_int4 above.
+ */
+#if 0
+#if defined(__linux__)
+# include <byteswap.h>
+# undef iswap_int8
+# undef iswap_int4
+# undef iswap_int2
+# define iswap_int8 bswap_64
+# define iswap_int4 bswap_32
+# define iswap_int2 bswap_16
+#endif
+#endif
+
+
+/*
+ * Macros to specify that data read in is of a particular endianness.
+ * The macros here swap to the appropriate order for the particular machine
+ * running the macro and return the new answer. These may also be used when
+ * writing to a file to specify that we wish to write in (eg) big endian
+ * format.
+ *
+ * This leads to efficient code as most of the time these macros are
+ * trivial.
+ */
+#ifdef SP_BIG_ENDIAN
+#define le_int4(x) iswap_int4((x))
+#define le_int2(x) iswap_int2((x))
+#endif
+
+#ifdef SP_LITTLE_ENDIAN
+#define le_int4(x) (x)
+#define le_int2(x) (x)
+#endif
+
+/*-----------------------------------------------------------------------------
+ * <inttypes.h> definitions, incase they're not present
+ */
+
+#ifndef PRId64
+#define __PRI64__ "l"
+#define PRId64 __PRI64__ "d"
+#define PRId32 "d"
+#define PRId16 "d"
+#define PRId8 "d"
+#define PRIu64 __PRI64__ "u"
+#define PRIu32 "u"
+#define PRIu16 "u"
+#define PRIu8 "u"
+#endif
+
+/*-----------------------------------------------------------------------------
+ * Operating system specifics.
+ * These ought to be done by autoconf, but are legacy code.
+ */
+/*
+ * SunOS 4.x
+ * Even though we use the ANSI gcc, we make use the the standard SunOS 4.x
+ * libraries and include files, which are non-ansi
+ */
+#if defined(__sun__) && !defined(__svr4__)
+#define SEEK_SET 0
+#define SEEK_CUR 1
+#define SEEK_END 2
+#endif
+
+/*
+ * Microsoft Visual C++
+ * Windows
+ */
+#if defined(_MSC_VER)
+#define popen _popen
+#define pclose _pclose
+#define ftruncate(fd,len) _chsize(fd,len)
+#endif
+
+
+/*
+ * Microsoft Windows running MinGW
+ */
+#if defined(__MINGW32__)
+/* #define mkdir(filename,mode) mkdir((filename)) */
+#define sysconf(x) 512
+#define ftruncate(fd,len) _chsize(fd,len)
+#endif
+
+/* Generic WIN32 API issues */
+#ifdef _WIN32
+# ifndef HAVE_FSEEKO
+# if __MSVCRT_VERSION__ >= 0x800
+ /* if you have MSVCR80 installed then you can use these definitions: */
+# define off_t __int64
+# define fseeko _fseeki64
+# define ftello _ftelli64
+# else
+ /* otherwise we're stuck with 32-bit file support */
+# define off_t long
+# define fseeko fseek
+# define ftello ftell
+# endif
+# endif /* !HAVE_FSEEKO */
+#endif /* _WIN32 */
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /*_OS_H_*/
--- /dev/null
+/*
+Copyright (c) 2009 Genome Research Ltd.
+Author: Rob Davies <rmd@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <stdlib.h>
+#include <stdio.h>
+#include <stdint.h>
+
+#include "cram/pooled_alloc.h"
+#include "cram/misc.h"
+
+//#define TEST_MAIN
+
+#define PSIZE 1024*1024
+
+// credit to http://graphics.stanford.edu/~seander/bithacks.html
+static int next_power_2(unsigned int v) {
+ v--;
+ v |= v >> 1;
+ v |= v >> 2;
+ v |= v >> 4;
+ v |= v >> 8;
+ v |= v >> 16;
+ v++;
+
+ return v;
+}
+
+/*
+ * Creates a pool.
+ * Pool allocations are approx minimum of 1024*dsize or PSIZE.
+ * (Assumes we're not trying to use pools for >= 2Gb or more)
+ */
+pool_alloc_t *pool_create(size_t dsize) {
+ pool_alloc_t *p;
+
+ if (NULL == (p = (pool_alloc_t *)malloc(sizeof(*p))))
+ return NULL;
+
+ /* Minimum size is a pointer, for free list */
+ dsize = (dsize + sizeof(void *) - 1) & ~(sizeof(void *)-1);
+ if (dsize < sizeof(void *))
+ dsize = sizeof(void *);
+ p->dsize = dsize;
+ p->psize = MIN(PSIZE, next_power_2(p->dsize*1024));
+
+ p->npools = 0;
+ p->pools = NULL;
+ p->free = NULL;
+
+ return p;
+}
+
+static pool_t *new_pool(pool_alloc_t *p) {
+ size_t n = p->psize / p->dsize;
+ pool_t *pool;
+
+ pool = realloc(p->pools, (p->npools + 1) * sizeof(*p->pools));
+ if (NULL == pool) return NULL;
+ p->pools = pool;
+ pool = &p->pools[p->npools];
+
+ pool->pool = malloc(n * p->dsize);
+ if (NULL == pool->pool) return NULL;
+
+ pool->used = 0;
+
+ p->npools++;
+
+ return pool;
+}
+
+void pool_destroy(pool_alloc_t *p) {
+ size_t i;
+
+ for (i = 0; i < p->npools; i++) {
+ free(p->pools[i].pool);
+ }
+ free(p->pools);
+ free(p);
+}
+
+void *pool_alloc(pool_alloc_t *p) {
+ pool_t *pool;
+ void *ret;
+
+ /* Look on free list */
+ if (NULL != p->free) {
+ ret = p->free;
+ p->free = *((void **)p->free);
+ return ret;
+ }
+
+ /* Look for space in the last pool */
+ if (p->npools) {
+ pool = &p->pools[p->npools - 1];
+ if (pool->used + p->dsize < p->psize) {
+ ret = ((char *) pool->pool) + pool->used;
+ pool->used += p->dsize;
+ return ret;
+ }
+ }
+
+ /* Need a new pool */
+ pool = new_pool(p);
+ if (NULL == pool) return NULL;
+
+ pool->used = p->dsize;
+ return pool->pool;
+}
+
+void pool_free(pool_alloc_t *p, void *ptr) {
+ *(void **)ptr = p->free;
+ p->free = ptr;
+}
+
+#ifdef TEST_MAIN
+typedef struct {
+ int x, y, z;
+} xyz;
+
+#define NP 10000
+int main(void) {
+ int i;
+ xyz *item;
+ xyz **items;
+ pool_alloc_t *p = pool_create(sizeof(xyz));
+
+ items = (xyz **)malloc(NP * sizeof(*items));
+
+ for (i = 0; i < NP; i++) {
+ item = pool_alloc(p);
+ item->x = i;
+ item->y = i+1;
+ item->z = i+2;
+ items[i] = item;
+ }
+
+ for (i = 0; i < NP; i++) {
+ item = items[i];
+ if (i % 3)
+ pool_free(p, item);
+ }
+
+ for (i = 0; i < NP; i++) {
+ item = pool_alloc(p);
+ item->x = 1000000+i;
+ item->y = 1000000+i+1;
+ item->z = 1000000+i+2;
+ }
+
+ for (i = 0; i < NP; i++) {
+ item = items[i];
+ printf("%d\t%d\t%d\t%d\n", i, item->x, item->y, item->z);
+ pool_free(p, item);
+ }
+
+ return 0;
+}
+#endif
--- /dev/null
+/*
+Copyright (c) 2009 Genome Research Ltd.
+Author: Rob Davies <rmd@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _POOLED_ALLOC_H_
+#define _POOLED_ALLOC_H_
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*
+ * Implements a pooled block allocator where all items are the same size,
+ * but we need many of them.
+ */
+typedef struct {
+ void *pool;
+ size_t used;
+} pool_t;
+
+typedef struct {
+ size_t dsize;
+ size_t psize;
+ size_t npools;
+ pool_t *pools;
+ void *free;
+} pool_alloc_t;
+
+pool_alloc_t *pool_create(size_t dsize);
+void pool_destroy(pool_alloc_t *p);
+void *pool_alloc(pool_alloc_t *p);
+void pool_free(pool_alloc_t *p, void *ptr);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /*_POOLED_ALLOC_H_*/
--- /dev/null
+/* rans_byte.h originally from https://github.com/rygorous/ryg_rans
+ *
+ * This is a public-domain implementation of several rANS variants. rANS is an
+ * entropy coder from the ANS family, as described in Jarek Duda's paper
+ * "Asymmetric numeral systems" (http://arxiv.org/abs/1311.2540).
+ */
+
+/*-------------------------------------------------------------------------- */
+
+// Simple byte-aligned rANS encoder/decoder - public domain - Fabian 'ryg' Giesen 2014
+//
+// Not intended to be "industrial strength"; just meant to illustrate the general
+// idea.
+
+#ifndef RANS_BYTE_HEADER
+#define RANS_BYTE_HEADER
+
+#include <stdint.h>
+
+#ifdef assert
+#define RansAssert assert
+#else
+#define RansAssert(x)
+#endif
+
+// READ ME FIRST:
+//
+// This is designed like a typical arithmetic coder API, but there's three
+// twists you absolutely should be aware of before you start hacking:
+//
+// 1. You need to encode data in *reverse* - last symbol first. rANS works
+// like a stack: last in, first out.
+// 2. Likewise, the encoder outputs bytes *in reverse* - that is, you give
+// it a pointer to the *end* of your buffer (exclusive), and it will
+// slowly move towards the beginning as more bytes are emitted.
+// 3. Unlike basically any other entropy coder implementation you might
+// have used, you can interleave data from multiple independent rANS
+// encoders into the same bytestream without any extra signaling;
+// you can also just write some bytes by yourself in the middle if
+// you want to. This is in addition to the usual arithmetic encoder
+// property of being able to switch models on the fly. Writing raw
+// bytes can be useful when you have some data that you know is
+// incompressible, and is cheaper than going through the rANS encode
+// function. Using multiple rANS coders on the same byte stream wastes
+// a few bytes compared to using just one, but execution of two
+// independent encoders can happen in parallel on superscalar and
+// Out-of-Order CPUs, so this can be *much* faster in tight decoding
+// loops.
+//
+// This is why all the rANS functions take the write pointer as an
+// argument instead of just storing it in some context struct.
+
+// --------------------------------------------------------------------------
+
+// L ('l' in the paper) is the lower bound of our normalization interval.
+// Between this and our byte-aligned emission, we use 31 (not 32!) bits.
+// This is done intentionally because exact reciprocals for 31-bit uints
+// fit in 32-bit uints: this permits some optimizations during encoding.
+#define RANS_BYTE_L (1u << 23) // lower bound of our normalization interval
+
+// State for a rANS encoder. Yep, that's all there is to it.
+typedef uint32_t RansState;
+
+// Initialize a rANS encoder.
+static inline void RansEncInit(RansState* r)
+{
+ *r = RANS_BYTE_L;
+}
+
+// Renormalize the encoder. Internal function.
+static inline RansState RansEncRenorm(RansState x, uint8_t** pptr, uint32_t freq, uint32_t scale_bits)
+{
+ uint32_t x_max = ((RANS_BYTE_L >> scale_bits) << 8) * freq; // this turns into a shift.
+ if (x >= x_max) {
+ uint8_t* ptr = *pptr;
+ do {
+ *--ptr = (uint8_t) (x & 0xff);
+ x >>= 8;
+ } while (x >= x_max);
+ *pptr = ptr;
+ }
+ return x;
+}
+
+// Encodes a single symbol with range start "start" and frequency "freq".
+// All frequencies are assumed to sum to "1 << scale_bits", and the
+// resulting bytes get written to ptr (which is updated).
+//
+// NOTE: With rANS, you need to encode symbols in *reverse order*, i.e. from
+// beginning to end! Likewise, the output bytestream is written *backwards*:
+// ptr starts pointing at the end of the output buffer and keeps decrementing.
+static inline void RansEncPut(RansState* r, uint8_t** pptr, uint32_t start, uint32_t freq, uint32_t scale_bits)
+{
+ // renormalize
+ RansState x = RansEncRenorm(*r, pptr, freq, scale_bits);
+
+ // x = C(s,x)
+ *r = ((x / freq) << scale_bits) + (x % freq) + start;
+}
+
+// Flushes the rANS encoder.
+static inline void RansEncFlush(RansState* r, uint8_t** pptr)
+{
+ uint32_t x = *r;
+ uint8_t* ptr = *pptr;
+
+ ptr -= 4;
+ ptr[0] = (uint8_t) (x >> 0);
+ ptr[1] = (uint8_t) (x >> 8);
+ ptr[2] = (uint8_t) (x >> 16);
+ ptr[3] = (uint8_t) (x >> 24);
+
+ *pptr = ptr;
+}
+
+// Initializes a rANS decoder.
+// Unlike the encoder, the decoder works forwards as you'd expect.
+static inline void RansDecInit(RansState* r, uint8_t** pptr)
+{
+ uint32_t x;
+ uint8_t* ptr = *pptr;
+
+ x = ptr[0] << 0;
+ x |= ptr[1] << 8;
+ x |= ptr[2] << 16;
+ x |= ptr[3] << 24;
+ ptr += 4;
+
+ *pptr = ptr;
+ *r = x;
+}
+
+// Returns the current cumulative frequency (map it to a symbol yourself!)
+static inline uint32_t RansDecGet(RansState* r, uint32_t scale_bits)
+{
+ return *r & ((1u << scale_bits) - 1);
+}
+
+// Advances in the bit stream by "popping" a single symbol with range start
+// "start" and frequency "freq". All frequencies are assumed to sum to "1 << scale_bits",
+// and the resulting bytes get written to ptr (which is updated).
+static inline void RansDecAdvance(RansState* r, uint8_t** pptr, uint32_t start, uint32_t freq, uint32_t scale_bits)
+{
+ uint32_t mask = (1u << scale_bits) - 1;
+
+ // s, x = D(x)
+ uint32_t x = *r;
+ x = freq * (x >> scale_bits) + (x & mask) - start;
+
+ // renormalize
+ if (x < RANS_BYTE_L) {
+ uint8_t* ptr = *pptr;
+ do x = (x << 8) | *ptr++; while (x < RANS_BYTE_L);
+ *pptr = ptr;
+ }
+
+ *r = x;
+}
+
+// --------------------------------------------------------------------------
+
+// That's all you need for a full encoder; below here are some utility
+// functions with extra convenience or optimizations.
+
+// Encoder symbol description
+// This (admittedly odd) selection of parameters was chosen to make
+// RansEncPutSymbol as cheap as possible.
+typedef struct {
+ uint32_t x_max; // (Exclusive) upper bound of pre-normalization interval
+ uint32_t rcp_freq; // Fixed-point reciprocal frequency
+ uint32_t bias; // Bias
+ uint16_t cmpl_freq; // Complement of frequency: (1 << scale_bits) - freq
+ uint16_t rcp_shift; // Reciprocal shift
+} RansEncSymbol;
+
+// Decoder symbols are straightforward.
+typedef struct {
+ uint16_t start; // Start of range.
+ uint16_t freq; // Symbol frequency.
+} RansDecSymbol;
+
+// Initializes an encoder symbol to start "start" and frequency "freq"
+static inline void RansEncSymbolInit(RansEncSymbol* s, uint32_t start, uint32_t freq, uint32_t scale_bits)
+{
+ RansAssert(scale_bits <= 16);
+ RansAssert(start <= (1u << scale_bits));
+ RansAssert(freq <= (1u << scale_bits) - start);
+
+ // Say M := 1 << scale_bits.
+ //
+ // The original encoder does:
+ // x_new = (x/freq)*M + start + (x%freq)
+ //
+ // The fast encoder does (schematically):
+ // q = mul_hi(x, rcp_freq) >> rcp_shift (division)
+ // r = x - q*freq (remainder)
+ // x_new = q*M + bias + r (new x)
+ // plugging in r into x_new yields:
+ // x_new = bias + x + q*(M - freq)
+ // =: bias + x + q*cmpl_freq (*)
+ //
+ // and we can just precompute cmpl_freq. Now we just need to
+ // set up our parameters such that the original encoder and
+ // the fast encoder agree.
+
+ s->x_max = ((RANS_BYTE_L >> scale_bits) << 8) * freq;
+ s->cmpl_freq = (uint16_t) ((1 << scale_bits) - freq);
+ if (freq < 2) {
+ // freq=0 symbols are never valid to encode, so it doesn't matter what
+ // we set our values to.
+ //
+ // freq=1 is tricky, since the reciprocal of 1 is 1; unfortunately,
+ // our fixed-point reciprocal approximation can only multiply by values
+ // smaller than 1.
+ //
+ // So we use the "next best thing": rcp_freq=0xffffffff, rcp_shift=0.
+ // This gives:
+ // q = mul_hi(x, rcp_freq) >> rcp_shift
+ // = mul_hi(x, (1<<32) - 1)) >> 0
+ // = floor(x - x/(2^32))
+ // = x - 1 if 1 <= x < 2^32
+ // and we know that x>0 (x=0 is never in a valid normalization interval).
+ //
+ // So we now need to choose the other parameters such that
+ // x_new = x*M + start
+ // plug it in:
+ // x*M + start (desired result)
+ // = bias + x + q*cmpl_freq (*)
+ // = bias + x + (x - 1)*(M - 1) (plug in q=x-1, cmpl_freq)
+ // = bias + 1 + (x - 1)*M
+ // = x*M + (bias + 1 - M)
+ //
+ // so we have start = bias + 1 - M, or equivalently
+ // bias = start + M - 1.
+ s->rcp_freq = ~0u;
+ s->rcp_shift = 0;
+ s->bias = start + (1 << scale_bits) - 1;
+ } else {
+ // Alverson, "Integer Division using reciprocals"
+ // shift=ceil(log2(freq))
+ uint32_t shift = 0;
+ while (freq > (1u << shift))
+ shift++;
+
+ s->rcp_freq = (uint32_t) (((1ull << (shift + 31)) + freq-1) / freq);
+ s->rcp_shift = shift - 1;
+
+ // With these values, 'q' is the correct quotient, so we
+ // have bias=start.
+ s->bias = start;
+ }
+
+ s->rcp_shift += 32; // Avoid the extra >>32 in RansEncPutSymbol
+}
+
+// Initialize a decoder symbol to start "start" and frequency "freq"
+static inline void RansDecSymbolInit(RansDecSymbol* s, uint32_t start, uint32_t freq)
+{
+ RansAssert(start <= (1 << 16));
+ RansAssert(freq <= (1 << 16) - start);
+ s->start = (uint16_t) start;
+ s->freq = (uint16_t) freq;
+}
+
+// Encodes a given symbol. This is faster than straight RansEnc since we can do
+// multiplications instead of a divide.
+//
+// See RansEncSymbolInit for a description of how this works.
+static inline void RansEncPutSymbol(RansState* r, uint8_t** pptr, RansEncSymbol const* sym)
+{
+ RansAssert(sym->x_max != 0); // can't encode symbol with freq=0
+
+ // renormalize
+ uint32_t x = *r;
+ uint32_t x_max = sym->x_max;
+
+ if (x >= x_max) {
+ uint8_t* ptr = *pptr;
+ do {
+ *--ptr = (uint8_t) (x & 0xff);
+ x >>= 8;
+ } while (x >= x_max);
+ *pptr = ptr;
+ }
+
+ // x = C(s,x)
+ // NOTE: written this way so we get a 32-bit "multiply high" when
+ // available. If you're on a 64-bit platform with cheap multiplies
+ // (e.g. x64), just bake the +32 into rcp_shift.
+ //uint32_t q = (uint32_t) (((uint64_t)x * sym->rcp_freq) >> 32) >> sym->rcp_shift;
+
+ // The extra >>32 has already been added to RansEncSymbolInit
+ uint32_t q = (uint32_t) (((uint64_t)x * sym->rcp_freq) >> sym->rcp_shift);
+ *r = x + sym->bias + q * sym->cmpl_freq;
+}
+
+// Equivalent to RansDecAdvance that takes a symbol.
+static inline void RansDecAdvanceSymbol(RansState* r, uint8_t** pptr, RansDecSymbol const* sym, uint32_t scale_bits)
+{
+ RansDecAdvance(r, pptr, sym->start, sym->freq, scale_bits);
+}
+
+// Advances in the bit stream by "popping" a single symbol with range start
+// "start" and frequency "freq". All frequencies are assumed to sum to "1 << scale_bits".
+// No renormalization or output happens.
+static inline void RansDecAdvanceStep(RansState* r, uint32_t start, uint32_t freq, uint32_t scale_bits)
+{
+ uint32_t mask = (1u << scale_bits) - 1;
+
+ // s, x = D(x)
+ uint32_t x = *r;
+ *r = freq * (x >> scale_bits) + (x & mask) - start;
+}
+
+// Equivalent to RansDecAdvanceStep that takes a symbol.
+static inline void RansDecAdvanceSymbolStep(RansState* r, RansDecSymbol const* sym, uint32_t scale_bits)
+{
+ RansDecAdvanceStep(r, sym->start, sym->freq, scale_bits);
+}
+
+// Renormalize.
+static inline void RansDecRenorm(RansState* r, uint8_t** pptr)
+{
+ // renormalize
+ uint32_t x = *r;
+
+ if (x < RANS_BYTE_L) {
+ uint8_t* ptr = *pptr;
+ do x = (x << 8) | *ptr++; while (x < RANS_BYTE_L);
+ *pptr = ptr;
+ }
+
+ *r = x;
+}
+
+#endif // RANS_BYTE_HEADER
--- /dev/null
+/*
+ * Copyright (c) 2014 Genome Research Ltd.
+ * Author(s): James Bonfield
+ *
+ * Redistribution and use in source and binary forms, with or without
+ * modification, are permitted provided that the following conditions are met:
+ *
+ * 1. Redistributions of source code must retain the above copyright notice,
+ * this list of conditions and the following disclaimer.
+ *
+ * 2. Redistributions in binary form must reproduce the above
+ * copyright notice, this list of conditions and the following
+ * disclaimer in the documentation and/or other materials provided
+ * with the distribution.
+ *
+ * 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+ * Institute nor the names of its contributors may be used to endorse
+ * or promote products derived from this software without specific
+ * prior written permission.
+ *
+ * THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS
+ * IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED
+ * TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A
+ * PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH
+ * LTD OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL,
+ * SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT
+ * LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE,
+ * DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY
+ * THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+ * (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+ * OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+ */
+
+/*
+ * Author: James Bonfield, Wellcome Trust Sanger Institute. 2014
+ */
+
+#include <config.h>
+
+#include <stdint.h>
+#include <stdlib.h>
+#include <stdio.h>
+#include <unistd.h>
+#include <assert.h>
+#include <string.h>
+#include <sys/time.h>
+
+#include "cram/rANS_static.h"
+#include "cram/rANS_byte.h"
+
+#define TF_SHIFT 12
+#define TOTFREQ (1<<TF_SHIFT)
+
+#define ABS(a) ((a)>0?(a):-(a))
+#ifndef BLK_SIZE
+# define BLK_SIZE 1024*1024
+#endif
+
+// Room to allow for expanded BLK_SIZE on worst case compression.
+#define BLK_SIZE2 ((int)(1.05*BLK_SIZE))
+
+/*-----------------------------------------------------------------------------
+ * Memory to memory compression functions.
+ *
+ * These are original versions without any manual loop unrolling. They
+ * are easier to understand, but can be up to 2x slower.
+ */
+
+unsigned char *rans_compress_O0(unsigned char *in, unsigned int in_size,
+ unsigned int *out_size) {
+ unsigned char *out_buf = malloc(1.05*in_size + 257*257*3 + 9);
+ unsigned char *cp, *out_end;
+ RansEncSymbol syms[256];
+ RansState rans0, rans1, rans2, rans3;
+ uint8_t* ptr;
+ int F[256] = {0}, i, j, tab_size, rle, x, fsum = 0;
+ int m = 0, M = 0;
+ uint64_t tr;
+
+ if (!out_buf)
+ return NULL;
+
+ ptr = out_end = out_buf + (int)(1.05*in_size) + 257*257*3 + 9;
+
+ // Compute statistics
+ for (i = 0; i < in_size; i++) {
+ F[in[i]]++;
+ }
+ tr = ((uint64_t)TOTFREQ<<31)/in_size + (1<<30)/in_size;
+
+ // Normalise so T[i] == TOTFREQ
+ for (m = M = j = 0; j < 256; j++) {
+ if (!F[j])
+ continue;
+
+ if (m < F[j])
+ m = F[j], M = j;
+
+ if ((F[j] = (F[j]*tr)>>31) == 0)
+ F[j] = 1;
+ fsum += F[j];
+ }
+
+ fsum++;
+ if (fsum < TOTFREQ)
+ F[M] += TOTFREQ-fsum;
+ else
+ F[M] -= fsum-TOTFREQ;
+
+ //printf("F[%d]=%d\n", M, F[M]);
+ assert(F[M]>0);
+
+ // Encode statistics.
+ cp = out_buf+9;
+
+ for (x = rle = j = 0; j < 256; j++) {
+ if (F[j]) {
+ // j
+ if (rle) {
+ rle--;
+ } else {
+ *cp++ = j;
+ if (!rle && j && F[j-1]) {
+ for(rle=j+1; rle<256 && F[rle]; rle++)
+ ;
+ rle -= j+1;
+ *cp++ = rle;
+ }
+ //fprintf(stderr, "%d: %d %d\n", j, rle, N[j]);
+ }
+
+ // F[j]
+ if (F[j]<128) {
+ *cp++ = F[j];
+ } else {
+ *cp++ = 128 | (F[j]>>8);
+ *cp++ = F[j]&0xff;
+ }
+ RansEncSymbolInit(&syms[j], x, F[j], TF_SHIFT);
+ x += F[j];
+ }
+ }
+ *cp++ = 0;
+
+ //write(1, out_buf+4, cp-(out_buf+4));
+ tab_size = cp-out_buf;
+
+ RansEncInit(&rans0);
+ RansEncInit(&rans1);
+ RansEncInit(&rans2);
+ RansEncInit(&rans3);
+
+ switch (i=(in_size&3)) {
+ case 3: RansEncPutSymbol(&rans2, &ptr, &syms[in[in_size-(i-2)]]);
+ case 2: RansEncPutSymbol(&rans1, &ptr, &syms[in[in_size-(i-1)]]);
+ case 1: RansEncPutSymbol(&rans0, &ptr, &syms[in[in_size-(i-0)]]);
+ case 0:
+ break;
+ }
+ for (i=(in_size &~3); i>0; i-=4) {
+ RansEncSymbol *s3 = &syms[in[i-1]];
+ RansEncSymbol *s2 = &syms[in[i-2]];
+ RansEncSymbol *s1 = &syms[in[i-3]];
+ RansEncSymbol *s0 = &syms[in[i-4]];
+
+ RansEncPutSymbol(&rans3, &ptr, s3);
+ RansEncPutSymbol(&rans2, &ptr, s2);
+ RansEncPutSymbol(&rans1, &ptr, s1);
+ RansEncPutSymbol(&rans0, &ptr, s0);
+ }
+
+ RansEncFlush(&rans3, &ptr);
+ RansEncFlush(&rans2, &ptr);
+ RansEncFlush(&rans1, &ptr);
+ RansEncFlush(&rans0, &ptr);
+
+ // Finalise block size and return it
+ *out_size = (out_end - ptr) + tab_size;
+
+ cp = out_buf;
+
+ *cp++ = 0; // order
+ *cp++ = ((*out_size-9)>> 0) & 0xff;
+ *cp++ = ((*out_size-9)>> 8) & 0xff;
+ *cp++ = ((*out_size-9)>>16) & 0xff;
+ *cp++ = ((*out_size-9)>>24) & 0xff;
+
+ *cp++ = (in_size>> 0) & 0xff;
+ *cp++ = (in_size>> 8) & 0xff;
+ *cp++ = (in_size>>16) & 0xff;
+ *cp++ = (in_size>>24) & 0xff;
+
+ memmove(out_buf + tab_size, ptr, out_end-ptr);
+
+ return out_buf;
+}
+
+typedef struct {
+ struct {
+ int F;
+ int C;
+ } fc[256];
+ unsigned char *R;
+} ari_decoder;
+
+unsigned char *rans_uncompress_O0(unsigned char *in, unsigned int in_size,
+ unsigned int *out_size) {
+ /* Load in the static tables */
+ unsigned char *cp = in + 9;
+ int i, j, x, out_sz, in_sz, rle;
+ char *out_buf;
+ ari_decoder D;
+ RansDecSymbol syms[256];
+
+ memset(&D, 0, sizeof(D));
+
+ if (*in++ != 0) // Order-0 check
+ return NULL;
+
+ in_sz = ((in[0])<<0) | ((in[1])<<8) | ((in[2])<<16) | ((in[3])<<24);
+ out_sz = ((in[4])<<0) | ((in[5])<<8) | ((in[6])<<16) | ((in[7])<<24);
+ if (in_sz != in_size-9)
+ return NULL;
+
+ out_buf = malloc(out_sz);
+ if (!out_buf)
+ return NULL;
+
+ //fprintf(stderr, "out_sz=%d\n", out_sz);
+
+ // Precompute reverse lookup of frequency.
+ rle = x = 0;
+ j = *cp++;
+ do {
+ if ((D.fc[j].F = *cp++) >= 128) {
+ D.fc[j].F &= ~128;
+ D.fc[j].F = ((D.fc[j].F & 127) << 8) | *cp++;
+ }
+ D.fc[j].C = x;
+
+ RansDecSymbolInit(&syms[j], D.fc[j].C, D.fc[j].F);
+
+ /* Build reverse lookup table */
+ if (!D.R) D.R = (unsigned char *)malloc(TOTFREQ);
+ memset(&D.R[x], j, D.fc[j].F);
+
+ x += D.fc[j].F;
+
+ if (!rle && j+1 == *cp) {
+ j = *cp++;
+ rle = *cp++;
+ } else if (rle) {
+ rle--;
+ j++;
+ } else {
+ j = *cp++;
+ }
+ } while(j);
+
+ assert(x < TOTFREQ);
+
+ RansState rans0, rans1, rans2, rans3;
+ uint8_t *ptr = cp;
+ RansDecInit(&rans0, &ptr);
+ RansDecInit(&rans1, &ptr);
+ RansDecInit(&rans2, &ptr);
+ RansDecInit(&rans3, &ptr);
+
+ int out_end = (out_sz&~3);
+
+ RansState R[4];
+ R[0] = rans0;
+ R[1] = rans1;
+ R[2] = rans2;
+ R[3] = rans3;
+ uint32_t mask = (1u << TF_SHIFT)-1;
+
+ for (i=0; i < out_end; i+=4) {
+ uint32_t m[4] = {R[0] & mask,
+ R[1] & mask,
+ R[2] & mask,
+ R[3] & mask};
+ uint8_t c[4] = {D.R[m[0]],
+ D.R[m[1]],
+ D.R[m[2]],
+ D.R[m[3]]};
+ out_buf[i+0] = c[0];
+ out_buf[i+1] = c[1];
+ out_buf[i+2] = c[2];
+ out_buf[i+3] = c[3];
+
+ // RansDecAdvanceSymbolStep(&R[0], &syms[c[0]], TF_SHIFT);
+ // RansDecAdvanceSymbolStep(&R[1], &syms[c[1]], TF_SHIFT);
+ // RansDecAdvanceSymbolStep(&R[2], &syms[c[2]], TF_SHIFT);
+ // RansDecAdvanceSymbolStep(&R[3], &syms[c[3]], TF_SHIFT);
+ R[0] = syms[c[0]].freq * (R[0]>>TF_SHIFT);
+ R[1] = syms[c[1]].freq * (R[1]>>TF_SHIFT);
+ R[2] = syms[c[2]].freq * (R[2]>>TF_SHIFT);
+ R[3] = syms[c[3]].freq * (R[3]>>TF_SHIFT);
+
+ R[0] += m[0] - syms[c[0]].start;
+ R[1] += m[1] - syms[c[1]].start;
+ R[2] += m[2] - syms[c[2]].start;
+ R[3] += m[3] - syms[c[3]].start;
+
+ RansDecRenorm(&R[0], &ptr);
+ RansDecRenorm(&R[1], &ptr);
+ RansDecRenorm(&R[2], &ptr);
+ RansDecRenorm(&R[3], &ptr);
+ }
+
+ rans0 = R[0];
+ rans1 = R[1];
+ rans2 = R[2];
+ rans3 = R[3];
+
+ switch(out_sz&3) {
+ unsigned char c;
+ case 0:
+ break;
+ case 1:
+ c = D.R[RansDecGet(&rans0, TF_SHIFT)];
+ RansDecAdvanceSymbol(&rans0, &ptr, &syms[c], TF_SHIFT);
+ out_buf[out_end] = c;
+ break;
+
+ case 2:
+ c = D.R[RansDecGet(&rans0, TF_SHIFT)];
+ RansDecAdvanceSymbol(&rans0, &ptr, &syms[c], TF_SHIFT);
+ out_buf[out_end] = c;
+
+ c = D.R[RansDecGet(&rans1, TF_SHIFT)];
+ RansDecAdvanceSymbol(&rans1, &ptr, &syms[c], TF_SHIFT);
+ out_buf[out_end+1] = c;
+ break;
+
+ case 3:
+ c = D.R[RansDecGet(&rans0, TF_SHIFT)];
+ RansDecAdvanceSymbol(&rans0, &ptr, &syms[c], TF_SHIFT);
+ out_buf[out_end] = c;
+
+ c = D.R[RansDecGet(&rans1, TF_SHIFT)];
+ RansDecAdvanceSymbol(&rans1, &ptr, &syms[c], TF_SHIFT);
+ out_buf[out_end+1] = c;
+
+ c = D.R[RansDecGet(&rans2, TF_SHIFT)];
+ RansDecAdvanceSymbol(&rans2, &ptr, &syms[c], TF_SHIFT);
+ out_buf[out_end+2] = c;
+ break;
+ }
+
+ *out_size = out_sz;
+
+ if (D.R) free(D.R);
+
+ return (unsigned char *)out_buf;
+}
+
+unsigned char *rans_compress_O1(unsigned char *in, unsigned int in_size,
+ unsigned int *out_size) {
+ unsigned char *out_buf = NULL, *out_end, *cp;
+ unsigned int last_i, tab_size, rle_i, rle_j;
+ RansEncSymbol (*syms)[256] = NULL; /* syms[256][256] */
+ int (*F)[256] = NULL; /* F[256][256] */
+ int *T = NULL; /* T[256] */
+ int i, j;
+ unsigned char c;
+
+ if (in_size < 4)
+ return rans_compress_O0(in, in_size, out_size);
+
+ syms = malloc(256 * sizeof(*syms));
+ if (!syms) goto cleanup;
+ F = calloc(256, sizeof(*F));
+ if (!F) goto cleanup;
+ T = calloc(256, sizeof(*T));
+ if (!T) goto cleanup;
+ out_buf = malloc(1.05*in_size + 257*257*3 + 9);
+ if (!out_buf) goto cleanup;
+
+ out_end = out_buf + (int)(1.05*in_size) + 257*257*3 + 9;
+ cp = out_buf+9;
+
+ //for (last = 0, i=in_size-1; i>=0; i--) {
+ // F[last][c = in[i]]++;
+ // T[last]++;
+ // last = c;
+ //}
+
+ for (last_i=i=0; i<in_size; i++) {
+ F[last_i][c = in[i]]++;
+ T[last_i]++;
+ last_i = c;
+ }
+ F[0][in[1*(in_size>>2)]]++;
+ F[0][in[2*(in_size>>2)]]++;
+ F[0][in[3*(in_size>>2)]]++;
+ T[0]+=3;
+
+ // Normalise so T[i] == TOTFREQ
+ for (rle_i = i = 0; i < 256; i++) {
+ int t2, m, M;
+ unsigned int x;
+
+ if (T[i] == 0)
+ continue;
+
+ //uint64_t p = (TOTFREQ * TOTFREQ) / t;
+ double p = ((double)TOTFREQ)/T[i];
+ for (t2 = m = M = j = 0; j < 256; j++) {
+ if (!F[i][j])
+ continue;
+
+ if (m < F[i][j])
+ m = F[i][j], M = j;
+
+ //if ((F[i][j] = (F[i][j] * p) / TOTFREQ) == 0)
+ if ((F[i][j] *= p) == 0)
+ F[i][j] = 1;
+ t2 += F[i][j];
+ }
+
+ t2++;
+ if (t2 < TOTFREQ)
+ F[i][M] += TOTFREQ-t2;
+ else
+ F[i][M] -= t2-TOTFREQ;
+
+ // Store frequency table
+ // i
+ if (rle_i) {
+ rle_i--;
+ } else {
+ *cp++ = i;
+ // FIXME: could use order-0 statistics to observe which alphabet
+ // symbols are present and base RLE on that ordering instead.
+ if (i && T[i-1]) {
+ for(rle_i=i+1; rle_i<256 && T[rle_i]; rle_i++)
+ ;
+ rle_i -= i+1;
+ *cp++ = rle_i;
+ }
+ }
+
+ int *F_i_ = F[i];
+ x = 0;
+ rle_j = 0;
+ for (j = 0; j < 256; j++) {
+ if (F_i_[j]) {
+ //fprintf(stderr, "F[%d][%d]=%d, x=%d\n", i, j, F_i_[j], x);
+
+ // j
+ if (rle_j) {
+ rle_j--;
+ } else {
+ *cp++ = j;
+ if (!rle_j && j && F_i_[j-1]) {
+ for(rle_j=j+1; rle_j<256 && F_i_[rle_j]; rle_j++)
+ ;
+ rle_j -= j+1;
+ *cp++ = rle_j;
+ }
+ }
+
+ // F_i_[j]
+ if (F_i_[j]<128) {
+ *cp++ = F_i_[j];
+ } else {
+ *cp++ = 128 | (F_i_[j]>>8);
+ *cp++ = F_i_[j]&0xff;
+ }
+
+ RansEncSymbolInit(&syms[i][j], x, F_i_[j], TF_SHIFT);
+ x += F_i_[j];
+ }
+ }
+ *cp++ = 0;
+ }
+ *cp++ = 0;
+
+ //write(1, out_buf+4, cp-(out_buf+4));
+ tab_size = cp - out_buf;
+ assert(tab_size < 257*257*3);
+
+ RansState rans0, rans1, rans2, rans3;
+ RansEncInit(&rans0);
+ RansEncInit(&rans1);
+ RansEncInit(&rans2);
+ RansEncInit(&rans3);
+
+ uint8_t* ptr = out_end;
+
+ int isz4 = in_size>>2;
+ int i0 = 1*isz4-2;
+ int i1 = 2*isz4-2;
+ int i2 = 3*isz4-2;
+ int i3 = 4*isz4-2;
+
+ unsigned char l0 = in[i0+1];
+ unsigned char l1 = in[i1+1];
+ unsigned char l2 = in[i2+1];
+ unsigned char l3 = in[i3+1];
+
+ // Deal with the remainder
+ l3 = in[in_size-1];
+ for (i3 = in_size-2; i3 > 4*isz4-2; i3--) {
+ unsigned char c3 = in[i3];
+ RansEncPutSymbol(&rans3, &ptr, &syms[c3][l3]);
+ l3 = c3;
+ }
+
+ for (; i0 >= 0; i0--, i1--, i2--, i3--) {
+ unsigned char c0, c1, c2, c3;
+ RansEncSymbol *s3 = &syms[c3 = in[i3]][l3];
+ RansEncSymbol *s2 = &syms[c2 = in[i2]][l2];
+ RansEncSymbol *s1 = &syms[c1 = in[i1]][l1];
+ RansEncSymbol *s0 = &syms[c0 = in[i0]][l0];
+
+ RansEncPutSymbol(&rans3, &ptr, s3);
+ RansEncPutSymbol(&rans2, &ptr, s2);
+ RansEncPutSymbol(&rans1, &ptr, s1);
+ RansEncPutSymbol(&rans0, &ptr, s0);
+
+ l0 = c0;
+ l1 = c1;
+ l2 = c2;
+ l3 = c3;
+ }
+
+ RansEncPutSymbol(&rans3, &ptr, &syms[0][l3]);
+ RansEncPutSymbol(&rans2, &ptr, &syms[0][l2]);
+ RansEncPutSymbol(&rans1, &ptr, &syms[0][l1]);
+ RansEncPutSymbol(&rans0, &ptr, &syms[0][l0]);
+
+ RansEncFlush(&rans3, &ptr);
+ RansEncFlush(&rans2, &ptr);
+ RansEncFlush(&rans1, &ptr);
+ RansEncFlush(&rans0, &ptr);
+
+ *out_size = (out_end - ptr) + tab_size;
+
+ cp = out_buf;
+ *cp++ = 1; // order
+
+ *cp++ = ((*out_size-9)>> 0) & 0xff;
+ *cp++ = ((*out_size-9)>> 8) & 0xff;
+ *cp++ = ((*out_size-9)>>16) & 0xff;
+ *cp++ = ((*out_size-9)>>24) & 0xff;
+
+ *cp++ = (in_size>> 0) & 0xff;
+ *cp++ = (in_size>> 8) & 0xff;
+ *cp++ = (in_size>>16) & 0xff;
+ *cp++ = (in_size>>24) & 0xff;
+
+ memmove(out_buf + tab_size, ptr, out_end-ptr);
+
+ cleanup:
+ free(syms);
+ free(F);
+ free(T);
+
+ return out_buf;
+}
+
+unsigned char *rans_uncompress_O1(unsigned char *in, unsigned int in_size,
+ unsigned int *out_size) {
+ /* Load in the static tables */
+ unsigned char *cp = in + 9;
+ int i, j = -999, x, out_sz, in_sz, rle_i, rle_j;
+ char *out_buf = NULL;
+ ari_decoder *D = NULL; /* D[256] */
+ RansDecSymbol (*syms)[256] = NULL; /* syms[256][256] */
+
+ if (*in++ != 1) // Order-1 check
+ return NULL;
+
+ in_sz = ((in[0])<<0) | ((in[1])<<8) | ((in[2])<<16) | ((in[3])<<24);
+ out_sz = ((in[4])<<0) | ((in[5])<<8) | ((in[6])<<16) | ((in[7])<<24);
+ if (in_sz != in_size-9)
+ return NULL;
+
+ D = calloc(256, sizeof(*D));
+ if (!D) goto cleanup;
+ syms = malloc(256 * sizeof(*syms));
+ if (!syms) goto cleanup;
+
+ //fprintf(stderr, "out_sz=%d\n", out_sz);
+
+ //i = *cp++;
+ rle_i = 0;
+ i = *cp++;
+ do {
+ rle_j = x = 0;
+ j = *cp++;
+ do {
+ if ((D[i].fc[j].F = *cp++) >= 128) {
+ D[i].fc[j].F &= ~128;
+ D[i].fc[j].F = ((D[i].fc[j].F & 127) << 8) | *cp++;
+ }
+ D[i].fc[j].C = x;
+
+ //fprintf(stderr, "i=%d j=%d F=%d C=%d\n", i, j, D[i].fc[j].F, D[i].fc[j].C);
+
+ if (!D[i].fc[j].F)
+ D[i].fc[j].F = TOTFREQ;
+
+ RansDecSymbolInit(&syms[i][j], D[i].fc[j].C, D[i].fc[j].F);
+
+ /* Build reverse lookup table */
+ if (!D[i].R) {
+ D[i].R = (unsigned char *)malloc(TOTFREQ);
+ if (!D[i].R)
+ goto cleanup;
+ }
+ memset(&D[i].R[x], j, D[i].fc[j].F);
+
+ x += D[i].fc[j].F;
+ assert(x <= TOTFREQ);
+
+ if (!rle_j && j+1 == *cp) {
+ j = *cp++;
+ rle_j = *cp++;
+ } else if (rle_j) {
+ rle_j--;
+ j++;
+ } else {
+ j = *cp++;
+ }
+ } while(j);
+
+ if (!rle_i && i+1 == *cp) {
+ i = *cp++;
+ rle_i = *cp++;
+ } else if (rle_i) {
+ rle_i--;
+ i++;
+ } else {
+ i = *cp++;
+ }
+ } while (i);
+
+ // Precompute reverse lookup of frequency.
+
+ RansState rans0, rans1, rans2, rans3;
+ uint8_t *ptr = cp;
+ RansDecInit(&rans0, &ptr);
+ RansDecInit(&rans1, &ptr);
+ RansDecInit(&rans2, &ptr);
+ RansDecInit(&rans3, &ptr);
+
+ int isz4 = out_sz>>2;
+ int l0 = 0;
+ int l1 = 0;
+ int l2 = 0;
+ int l3 = 0;
+ int i4[] = {0*isz4, 1*isz4, 2*isz4, 3*isz4};
+
+ RansState R[4];
+ R[0] = rans0;
+ R[1] = rans1;
+ R[2] = rans2;
+ R[3] = rans3;
+
+ /* Allocate output buffer */
+ out_buf = malloc(out_sz);
+ if (!out_buf) goto cleanup;
+
+ for (; i4[0] < isz4; i4[0]++, i4[1]++, i4[2]++, i4[3]++) {
+ uint32_t m[4] = {R[0] & ((1u << TF_SHIFT)-1),
+ R[1] & ((1u << TF_SHIFT)-1),
+ R[2] & ((1u << TF_SHIFT)-1),
+ R[3] & ((1u << TF_SHIFT)-1)};
+
+ uint8_t c[4] = {D[l0].R[m[0]],
+ D[l1].R[m[1]],
+ D[l2].R[m[2]],
+ D[l3].R[m[3]]};
+
+ out_buf[i4[0]] = c[0];
+ out_buf[i4[1]] = c[1];
+ out_buf[i4[2]] = c[2];
+ out_buf[i4[3]] = c[3];
+
+ //RansDecAdvanceSymbolStep(&R[0], &syms[l0][c[0]], TF_SHIFT);
+ //RansDecAdvanceSymbolStep(&R[1], &syms[l1][c[1]], TF_SHIFT);
+ //RansDecAdvanceSymbolStep(&R[2], &syms[l2][c[2]], TF_SHIFT);
+ //RansDecAdvanceSymbolStep(&R[3], &syms[l3][c[3]], TF_SHIFT);
+
+ R[0] = syms[l0][c[0]].freq * (R[0]>>TF_SHIFT);
+ R[1] = syms[l1][c[1]].freq * (R[1]>>TF_SHIFT);
+ R[2] = syms[l2][c[2]].freq * (R[2]>>TF_SHIFT);
+ R[3] = syms[l3][c[3]].freq * (R[3]>>TF_SHIFT);
+
+ R[0] += m[0] - syms[l0][c[0]].start;
+ R[1] += m[1] - syms[l1][c[1]].start;
+ R[2] += m[2] - syms[l2][c[2]].start;
+ R[3] += m[3] - syms[l3][c[3]].start;
+
+ RansDecRenorm(&R[0], &ptr);
+ RansDecRenorm(&R[1], &ptr);
+ RansDecRenorm(&R[2], &ptr);
+ RansDecRenorm(&R[3], &ptr);
+
+ l0 = c[0];
+ l1 = c[1];
+ l2 = c[2];
+ l3 = c[3];
+ }
+
+ rans0 = R[0];
+ rans1 = R[1];
+ rans2 = R[2];
+ rans3 = R[3];
+
+ // Remainder
+ for (; i4[3] < out_sz; i4[3]++) {
+ unsigned char c3 = D[l3].R[RansDecGet(&rans3, TF_SHIFT)];
+ out_buf[i4[3]] = c3;
+ RansDecAdvanceSymbol(&rans3, &ptr, &syms[l3][c3], TF_SHIFT);
+ l3 = c3;
+ }
+
+ *out_size = out_sz;
+
+ cleanup:
+ if (D) {
+ for (i = 0; i < 256; i++)
+ if (D[i].R) free(D[i].R);
+ free(D);
+ }
+ free(syms);
+
+ return (unsigned char *)out_buf;
+}
+
+/*-----------------------------------------------------------------------------
+ * Simple interface to the order-0 vs order-1 encoders and decoders.
+ */
+unsigned char *rans_compress(unsigned char *in, unsigned int in_size,
+ unsigned int *out_size, int order) {
+ return order
+ ? rans_compress_O1(in, in_size, out_size)
+ : rans_compress_O0(in, in_size, out_size);
+}
+
+unsigned char *rans_uncompress(unsigned char *in, unsigned int in_size,
+ unsigned int *out_size) {
+ /* Both rans_uncompress functions need to be able to read at least 9
+ bytes. */
+ if (in_size < 9)
+ return NULL;
+ return in[0]
+ ? rans_uncompress_O1(in, in_size, out_size)
+ : rans_uncompress_O0(in, in_size, out_size);
+}
+
+
+#ifdef TEST_MAIN
+/*-----------------------------------------------------------------------------
+ * Main.
+ *
+ * This is a simple command line tool for testing order-0 and order-1
+ * compression using the rANS codec. Simply compile with
+ *
+ * gcc -DTEST_MAIN -O3 -I. cram/rANS_static.c -o cram/rANS_static
+ *
+ * Usage: cram/rANS_static -o0 < file > file.o0
+ * cram/rANS_static -d < file.o0 > file2
+ *
+ * cram/rANS_static -o1 < file > file.o1
+ * cram/rANS_static -d < file.o1 > file2
+ */
+int main(int argc, char **argv) {
+ int opt, order = 0;
+ unsigned char in_buf[BLK_SIZE2+257*257*3];
+ int decode = 0;
+ FILE *infp = stdin, *outfp = stdout;
+ struct timeval tv1, tv2;
+ size_t bytes = 0;
+
+ extern char *optarg;
+ extern int optind;
+
+ while ((opt = getopt(argc, argv, "o:d")) != -1) {
+ switch (opt) {
+ case 'o':
+ order = atoi(optarg);
+ break;
+
+ case 'd':
+ decode = 1;
+ break;
+ }
+ }
+
+ order = order ? 1 : 0; // Only support O(0) and O(1)
+
+ if (optind < argc) {
+ if (!(infp = fopen(argv[optind], "rb"))) {
+ perror(argv[optind]);
+ return 1;
+ }
+ optind++;
+ }
+
+ if (optind < argc) {
+ if (!(outfp = fopen(argv[optind], "wb"))) {
+ perror(argv[optind]);
+ return 1;
+ }
+ optind++;
+ }
+
+ gettimeofday(&tv1, NULL);
+
+ if (decode) {
+ // Only used in some test implementations of RC_GetFreq()
+ //RC_init();
+ //RC_init2();
+
+ for (;;) {
+ uint32_t in_size, out_size;
+ unsigned char *out;
+
+ if (9 != fread(in_buf, 1, 9, infp))
+ break;
+ in_size = *(int *)&in_buf[1];
+ if (in_size != fread(in_buf+9, 1, in_size, infp)) {
+ fprintf(stderr, "Truncated input\n");
+ exit(1);
+ }
+ out = rans_uncompress(in_buf, in_size+9, &out_size);
+ if (!out)
+ abort();
+
+ fwrite(out, 1, out_size, outfp);
+ free(out);
+
+ bytes += out_size;
+ }
+ } else {
+ for (;;) {
+ uint32_t in_size, out_size;
+ unsigned char *out;
+
+ in_size = fread(in_buf, 1, BLK_SIZE, infp);
+ if (in_size <= 0)
+ break;
+
+ out = rans_compress(in_buf, in_size, &out_size, order);
+
+ fwrite(out, 1, out_size, outfp);
+ free(out);
+
+ bytes += in_size;
+ }
+ }
+
+ gettimeofday(&tv2, NULL);
+
+ fprintf(stderr, "Took %ld microseconds, %5.1f MB/s\n",
+ (long)(tv2.tv_sec - tv1.tv_sec)*1000000 +
+ tv2.tv_usec - tv1.tv_usec,
+ (double)bytes / ((long)(tv2.tv_sec - tv1.tv_sec)*1000000 +
+ tv2.tv_usec - tv1.tv_usec));
+ return 0;
+}
+#endif
--- /dev/null
+/*
+ * Copyright (c) 2014 Genome Research Ltd.
+ * Author(s): James Bonfield
+ *
+ * Redistribution and use in source and binary forms, with or without
+ * modification, are permitted provided that the following conditions are met:
+ *
+ * 1. Redistributions of source code must retain the above copyright notice,
+ * this list of conditions and the following disclaimer.
+ *
+ * 2. Redistributions in binary form must reproduce the above
+ * copyright notice, this list of conditions and the following
+ * disclaimer in the documentation and/or other materials provided
+ * with the distribution.
+ *
+ * 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+ * Institute nor the names of its contributors may be used to endorse
+ * or promote products derived from this software without specific
+ * prior written permission.
+ *
+ * THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS
+ * IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED
+ * TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A
+ * PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH
+ * LTD OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL,
+ * SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT
+ * LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE,
+ * DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY
+ * THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+ * (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+ * OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+ */
+
+
+#ifndef RANS_STATIC_H
+#define RANS_STATIC_H
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+unsigned char *rans_compress(unsigned char *in, unsigned int in_size,
+ unsigned int *out_size, int order);
+unsigned char *rans_uncompress(unsigned char *in, unsigned int in_size,
+ unsigned int *out_size);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* RANS_STATIC_H */
--- /dev/null
+/*
+Copyright (c) 2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <string.h>
+#include <assert.h>
+
+#include "cram/sam_header.h"
+#include "cram/string_alloc.h"
+
+static void sam_hdr_error(char *msg, char *line, int len, int lno) {
+ int j;
+
+ for (j = 0; j < len && line[j] != '\n'; j++)
+ ;
+ fprintf(stderr, "%s at line %d: \"%.*s\"\n", msg, lno, j, line);
+}
+
+void sam_hdr_dump(SAM_hdr *hdr) {
+ khint_t k;
+ int i;
+
+ printf("===DUMP===\n");
+ for (k = kh_begin(hdr->h); k != kh_end(hdr->h); k++) {
+ SAM_hdr_type *t1, *t2;
+ char c[2];
+
+ if (!kh_exist(hdr->h, k))
+ continue;
+
+ t1 = t2 = kh_val(hdr->h, k);
+ c[0] = kh_key(hdr->h, k)>>8;
+ c[1] = kh_key(hdr->h, k)&0xff;
+ printf("Type %.2s, count %d\n", c, t1->prev->order+1);
+
+ do {
+ SAM_hdr_tag *tag;
+ printf(">>>%d ", t1->order);
+ for (tag = t1->tag; tag; tag=tag->next) {
+ printf("\"%.2s\":\"%.*s\"\t",
+ tag->str, tag->len-3, tag->str+3);
+ }
+ putchar('\n');
+ t1 = t1->next;
+ } while (t1 != t2);
+ }
+
+ /* Dump out PG chains */
+ printf("\n@PG chains:\n");
+ for (i = 0; i < hdr->npg_end; i++) {
+ int j;
+ printf(" %d:", i);
+ for (j = hdr->pg_end[i]; j != -1; j = hdr->pg[j].prev_id) {
+ printf("%s%d(%.*s)",
+ j == hdr->pg_end[i] ? " " : "->",
+ j, hdr->pg[j].name_len, hdr->pg[j].name);
+ }
+ printf("\n");
+ }
+
+ puts("===END DUMP===");
+}
+
+/* Updates the hash tables in the SAM_hdr structure.
+ *
+ * Returns 0 on success;
+ * -1 on failure
+ */
+static int sam_hdr_update_hashes(SAM_hdr *sh,
+ int type,
+ SAM_hdr_type *h_type) {
+ /* Add to reference hash? */
+ if ((type>>8) == 'S' && (type&0xff) == 'Q') {
+ SAM_hdr_tag *tag;
+ SAM_SQ *new_ref;
+ int nref = sh->nref;
+
+ new_ref = realloc(sh->ref, (sh->nref+1)*sizeof(*sh->ref));
+ if (!new_ref)
+ return -1;
+ sh->ref = new_ref;
+
+ tag = h_type->tag;
+ sh->ref[nref].name = NULL;
+ sh->ref[nref].len = 0;
+ sh->ref[nref].ty = h_type;
+ sh->ref[nref].tag = tag;
+
+ while (tag) {
+ if (tag->str[0] == 'S' && tag->str[1] == 'N') {
+ if (!(sh->ref[nref].name = malloc(tag->len)))
+ return -1;
+ strncpy(sh->ref[nref].name, tag->str+3, tag->len-3);
+ sh->ref[nref].name[tag->len-3] = 0;
+ } else if (tag->str[0] == 'L' && tag->str[1] == 'N') {
+ sh->ref[nref].len = atoi(tag->str+3);
+ }
+ tag = tag->next;
+ }
+
+ if (sh->ref[nref].name) {
+ khint_t k;
+ int r;
+ k = kh_put(m_s2i, sh->ref_hash, sh->ref[nref].name, &r);
+ if (-1 == r) return -1;
+ kh_val(sh->ref_hash, k) = nref;
+ } else {
+ return -1; // SN should be present, according to spec.
+ }
+
+ sh->nref++;
+ }
+
+ /* Add to read-group hash? */
+ if ((type>>8) == 'R' && (type&0xff) == 'G') {
+ SAM_hdr_tag *tag;
+ SAM_RG *new_rg;
+ int nrg = sh->nrg;
+
+ new_rg = realloc(sh->rg, (sh->nrg+1)*sizeof(*sh->rg));
+ if (!new_rg)
+ return -1;
+ sh->rg = new_rg;
+
+ tag = h_type->tag;
+ sh->rg[nrg].name = NULL;
+ sh->rg[nrg].name_len = 0;
+ sh->rg[nrg].ty = h_type;
+ sh->rg[nrg].tag = tag;
+ sh->rg[nrg].id = nrg;
+
+ while (tag) {
+ if (tag->str[0] == 'I' && tag->str[1] == 'D') {
+ if (!(sh->rg[nrg].name = malloc(tag->len)))
+ return -1;
+ strncpy(sh->rg[nrg].name, tag->str+3, tag->len-3);
+ sh->rg[nrg].name[tag->len-3] = 0;
+ sh->rg[nrg].name_len = strlen(sh->rg[nrg].name);
+ }
+ tag = tag->next;
+ }
+
+ if (sh->rg[nrg].name) {
+ khint_t k;
+ int r;
+ k = kh_put(m_s2i, sh->rg_hash, sh->rg[nrg].name, &r);
+ if (-1 == r) return -1;
+ kh_val(sh->rg_hash, k) = nrg;
+ } else {
+ return -1; // ID should be present, according to spec.
+ }
+
+ sh->nrg++;
+ }
+
+ /* Add to program hash? */
+ if ((type>>8) == 'P' && (type&0xff) == 'G') {
+ SAM_hdr_tag *tag;
+ SAM_PG *new_pg;
+ int npg = sh->npg;
+
+ new_pg = realloc(sh->pg, (sh->npg+1)*sizeof(*sh->pg));
+ if (!new_pg)
+ return -1;
+ sh->pg = new_pg;
+
+ tag = h_type->tag;
+ sh->pg[npg].name = NULL;
+ sh->pg[npg].name_len = 0;
+ sh->pg[npg].ty = h_type;
+ sh->pg[npg].tag = tag;
+ sh->pg[npg].id = npg;
+ sh->pg[npg].prev_id = -1;
+
+ while (tag) {
+ if (tag->str[0] == 'I' && tag->str[1] == 'D') {
+ if (!(sh->pg[npg].name = malloc(tag->len)))
+ return -1;
+ strncpy(sh->pg[npg].name, tag->str+3, tag->len-3);
+ sh->pg[npg].name[tag->len-3] = 0;
+ sh->pg[npg].name_len = strlen(sh->pg[npg].name);
+ } else if (tag->str[0] == 'P' && tag->str[1] == 'P') {
+ // Resolve later if needed
+ khint_t k;
+ char tmp = tag->str[tag->len]; tag->str[tag->len] = 0;
+ k = kh_get(m_s2i, sh->pg_hash, tag->str+3);
+ tag->str[tag->len] = tmp;
+
+ if (k != kh_end(sh->pg_hash)) {
+ int p_id = kh_val(sh->pg_hash, k);
+ sh->pg[npg].prev_id = sh->pg[p_id].id;
+
+ /* Unmark previous entry as a PG termination */
+ if (sh->npg_end > 0 &&
+ sh->pg_end[sh->npg_end-1] == p_id) {
+ sh->npg_end--;
+ } else {
+ int i;
+ for (i = 0; i < sh->npg_end; i++) {
+ if (sh->pg_end[i] == p_id) {
+ memmove(&sh->pg_end[i], &sh->pg_end[i+1],
+ (sh->npg_end-i-1)*sizeof(*sh->pg_end));
+ sh->npg_end--;
+ }
+ }
+ }
+ } else {
+ sh->pg[npg].prev_id = -1;
+ }
+ }
+ tag = tag->next;
+ }
+
+ if (sh->pg[npg].name) {
+ khint_t k;
+ int r;
+ k = kh_put(m_s2i, sh->pg_hash, sh->pg[npg].name, &r);
+ if (-1 == r) return -1;
+ kh_val(sh->pg_hash, k) = npg;
+ } else {
+ return -1; // ID should be present, according to spec.
+ }
+
+ /* Add to npg_end[] array. Remove later if we find a PP line */
+ if (sh->npg_end >= sh->npg_end_alloc) {
+ int *new_pg_end;
+ int new_alloc = sh->npg_end_alloc ? sh->npg_end_alloc*2 : 4;
+
+ new_pg_end = realloc(sh->pg_end, new_alloc * sizeof(int));
+ if (!new_pg_end)
+ return -1;
+ sh->npg_end_alloc = new_alloc;
+ sh->pg_end = new_pg_end;
+ }
+ sh->pg_end[sh->npg_end++] = npg;
+
+ sh->npg++;
+ }
+
+ return 0;
+}
+
+/*
+ * Appends a formatted line to an existing SAM header.
+ * Line is a full SAM header record, eg "@SQ\tSN:foo\tLN:100", with
+ * optional new-line. If it contains more than 1 line then multiple lines
+ * will be added in order.
+ *
+ * Input text is of maximum length len or as terminated earlier by a NUL.
+ * Len may be 0 if unknown, in which case lines must be NUL-terminated.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int sam_hdr_add_lines(SAM_hdr *sh, const char *lines, int len) {
+ int i, lno, text_offset;
+ char *hdr;
+
+ if (!len)
+ len = strlen(lines);
+
+ text_offset = ks_len(&sh->text);
+ if (EOF == kputsn(lines, len, &sh->text))
+ return -1;
+ hdr = ks_str(&sh->text) + text_offset;
+
+ for (i = 0, lno = 1; i < len && hdr[i] != '\0'; i++, lno++) {
+ khint32_t type;
+ khint_t k;
+
+ int l_start = i, new;
+ SAM_hdr_type *h_type;
+ SAM_hdr_tag *h_tag, *last;
+
+ if (hdr[i] != '@') {
+ int j;
+ for (j = i; j < len && hdr[j] != '\0' && hdr[j] != '\n'; j++)
+ ;
+ sam_hdr_error("Header line does not start with '@'",
+ &hdr[l_start], len - l_start, lno);
+ return -1;
+ }
+
+ type = (hdr[i+1]<<8) | hdr[i+2];
+ if (hdr[i+1] < 'A' || hdr[i+1] > 'z' ||
+ hdr[i+2] < 'A' || hdr[i+2] > 'z') {
+ sam_hdr_error("Header line does not have a two character key",
+ &hdr[l_start], len - l_start, lno);
+ return -1;
+ }
+
+ i += 3;
+ if (hdr[i] == '\n')
+ continue;
+
+ // Add the header line type
+ if (!(h_type = pool_alloc(sh->type_pool)))
+ return -1;
+ if (-1 == (k = kh_put(sam_hdr, sh->h, type, &new)))
+ return -1;
+
+ // Form the ring, either with self or other lines of this type
+ if (!new) {
+ SAM_hdr_type *t = kh_val(sh->h, k), *p;
+ p = t->prev;
+
+ assert(p->next == t);
+ p->next = h_type;
+ h_type->prev = p;
+
+ t->prev = h_type;
+ h_type->next = t;
+ h_type->order = p->order+1;
+ } else {
+ kh_val(sh->h, k) = h_type;
+ h_type->prev = h_type->next = h_type;
+ h_type->order = 0;
+ }
+
+ // Parse the tags on this line
+ last = NULL;
+ if ((type>>8) == 'C' && (type&0xff) == 'O') {
+ int j;
+ if (hdr[i] != '\t') {
+ sam_hdr_error("Missing tab",
+ &hdr[l_start], len - l_start, lno);
+ return -1;
+ }
+
+ for (j = ++i; j < len && hdr[j] != '\0' && hdr[j] != '\n'; j++)
+ ;
+
+ if (!(h_type->tag = h_tag = pool_alloc(sh->tag_pool)))
+ return -1;
+ h_tag->str = string_ndup(sh->str_pool, &hdr[i], j-i);
+ h_tag->len = j-i;
+ h_tag->next = NULL;
+ if (!h_tag->str)
+ return -1;
+
+ i = j;
+
+ } else {
+ do {
+ int j;
+ if (hdr[i] != '\t') {
+ sam_hdr_error("Missing tab",
+ &hdr[l_start], len - l_start, lno);
+ return -1;
+ }
+
+ for (j = ++i; j < len && hdr[j] != '\0' && hdr[j] != '\n' && hdr[j] != '\t'; j++)
+ ;
+
+ if (!(h_tag = pool_alloc(sh->tag_pool)))
+ return -1;
+ h_tag->str = string_ndup(sh->str_pool, &hdr[i], j-i);
+ h_tag->len = j-i;
+ h_tag->next = NULL;
+ if (!h_tag->str)
+ return -1;
+
+ if (h_tag->len < 3 || h_tag->str[2] != ':') {
+ sam_hdr_error("Malformed key:value pair",
+ &hdr[l_start], len - l_start, lno);
+ return -1;
+ }
+
+ if (last)
+ last->next = h_tag;
+ else
+ h_type->tag = h_tag;
+
+ last = h_tag;
+ i = j;
+ } while (i < len && hdr[i] != '\0' && hdr[i] != '\n');
+ }
+
+ /* Update RG/SQ hashes */
+ if (-1 == sam_hdr_update_hashes(sh, type, h_type))
+ return -1;
+ }
+
+ return 0;
+}
+
+/*
+ * Adds a single line to a SAM header.
+ * Specify type and one or more key,value pairs, ending with the NULL key.
+ * Eg. sam_hdr_add(h, "SQ", "ID", "foo", "LN", "100", NULL).
+ *
+ * Returns index for specific entry on success (eg 2nd SQ, 4th RG)
+ * -1 on failure
+ */
+int sam_hdr_add(SAM_hdr *sh, const char *type, ...) {
+ va_list args;
+ va_start(args, type);
+ return sam_hdr_vadd(sh, type, args, NULL);
+}
+
+/*
+ * sam_hdr_add with a va_list interface.
+ *
+ * Note: this function invokes va_arg at least once, making the value
+ * of ap indeterminate after the return. The caller should call
+ * va_start/va_end before/after calling this function or use va_copy.
+ */
+int sam_hdr_vadd(SAM_hdr *sh, const char *type, va_list ap, ...) {
+ va_list args;
+ SAM_hdr_type *h_type;
+ SAM_hdr_tag *h_tag, *last;
+ int new;
+ khint32_t type_i = (type[0]<<8) | type[1], k;
+
+ if (EOF == kputc_('@', &sh->text))
+ return -1;
+ if (EOF == kputsn(type, 2, &sh->text))
+ return -1;
+
+ if (!(h_type = pool_alloc(sh->type_pool)))
+ return -1;
+ if (-1 == (k = kh_put(sam_hdr, sh->h, type_i, &new)))
+ return -1;
+
+ // Form the ring, either with self or other lines of this type
+ if (!new) {
+ SAM_hdr_type *t = kh_val(sh->h, k), *p;
+ p = t->prev;
+
+ assert(p->next == t);
+ p->next = h_type;
+ h_type->prev = p;
+
+ t->prev = h_type;
+ h_type->next = t;
+ h_type->order = p->order + 1;
+ } else {
+ kh_val(sh->h, k) = h_type;
+ h_type->prev = h_type->next = h_type;
+ h_type->order = 0;
+ }
+
+ last = NULL;
+
+ // Any ... varargs
+ va_start(args, ap);
+ for (;;) {
+ char *k, *v;
+ int idx;
+
+ if (!(k = (char *)va_arg(args, char *)))
+ break;
+ v = va_arg(args, char *);
+
+ if (EOF == kputc_('\t', &sh->text))
+ return -1;
+
+ if (!(h_tag = pool_alloc(sh->tag_pool)))
+ return -1;
+ idx = ks_len(&sh->text);
+
+ if (EOF == kputs(k, &sh->text))
+ return -1;
+ if (EOF == kputc_(':', &sh->text))
+ return -1;
+ if (EOF == kputs(v, &sh->text))
+ return -1;
+
+ h_tag->len = ks_len(&sh->text) - idx;
+ h_tag->str = string_ndup(sh->str_pool,
+ ks_str(&sh->text) + idx,
+ h_tag->len);
+ h_tag->next = NULL;
+ if (!h_tag->str)
+ return -1;
+
+ if (last)
+ last->next = h_tag;
+ else
+ h_type->tag = h_tag;
+
+ last = h_tag;
+ }
+ va_end(args);
+
+ // Plus the specified va_list params
+ for (;;) {
+ char *k, *v;
+ int idx;
+
+ if (!(k = (char *)va_arg(ap, char *)))
+ break;
+ v = va_arg(ap, char *);
+
+ if (EOF == kputc_('\t', &sh->text))
+ return -1;
+
+ if (!(h_tag = pool_alloc(sh->tag_pool)))
+ return -1;
+ idx = ks_len(&sh->text);
+
+ if (EOF == kputs(k, &sh->text))
+ return -1;
+ if (EOF == kputc_(':', &sh->text))
+ return -1;
+ if (EOF == kputs(v, &sh->text))
+ return -1;
+
+ h_tag->len = ks_len(&sh->text) - idx;
+ h_tag->str = string_ndup(sh->str_pool,
+ ks_str(&sh->text) + idx,
+ h_tag->len);
+ h_tag->next = NULL;
+ if (!h_tag->str)
+ return -1;
+
+ if (last)
+ last->next = h_tag;
+ else
+ h_type->tag = h_tag;
+
+ last = h_tag;
+ }
+ va_end(ap);
+
+ if (EOF == kputc('\n', &sh->text))
+ return -1;
+
+ int itype = (type[0]<<8) | type[1];
+ if (-1 == sam_hdr_update_hashes(sh, itype, h_type))
+ return -1;
+
+ return h_type->order;
+}
+
+/*
+ * Returns the first header item matching 'type'. If ID is non-NULL it checks
+ * for the tag ID: and compares against the specified ID.
+ *
+ * Returns NULL if no type/ID is found
+ */
+SAM_hdr_type *sam_hdr_find(SAM_hdr *hdr, char *type,
+ char *ID_key, char *ID_value) {
+ SAM_hdr_type *t1, *t2;
+ int itype = (type[0]<<8)|(type[1]);
+ khint_t k;
+
+ /* Special case for types we have prebuilt hashes on */
+ if (ID_key) {
+ if (type[0] == 'S' && type[1] == 'Q' &&
+ ID_key[0] == 'S' && ID_key[1] == 'N') {
+ k = kh_get(m_s2i, hdr->ref_hash, ID_value);
+ return k != kh_end(hdr->ref_hash)
+ ? hdr->ref[kh_val(hdr->ref_hash, k)].ty
+ : NULL;
+ }
+
+ if (type[0] == 'R' && type[1] == 'G' &&
+ ID_key[0] == 'I' && ID_key[1] == 'D') {
+ k = kh_get(m_s2i, hdr->rg_hash, ID_value);
+ return k != kh_end(hdr->rg_hash)
+ ? hdr->rg[kh_val(hdr->rg_hash, k)].ty
+ : NULL;
+ }
+
+ if (type[0] == 'P' && type[1] == 'G' &&
+ ID_key[0] == 'I' && ID_key[1] == 'D') {
+ k = kh_get(m_s2i, hdr->pg_hash, ID_value);
+ return k != kh_end(hdr->pg_hash)
+ ? hdr->pg[kh_val(hdr->pg_hash, k)].ty
+ : NULL;
+ }
+ }
+
+ k = kh_get(sam_hdr, hdr->h, itype);
+ if (k == kh_end(hdr->h))
+ return NULL;
+
+ if (!ID_key)
+ return kh_val(hdr->h, k);
+
+ t1 = t2 = kh_val(hdr->h, k);
+ do {
+ SAM_hdr_tag *tag;
+ for (tag = t1->tag; tag; tag = tag->next) {
+ if (tag->str[0] == ID_key[0] && tag->str[1] == ID_key[1]) {
+ char *cp1 = tag->str+3;
+ char *cp2 = ID_value;
+ while (*cp1 && *cp1 == *cp2)
+ cp1++, cp2++;
+ if (*cp2 || *cp1)
+ continue;
+ return t1;
+ }
+ }
+ t1 = t1->next;
+ } while (t1 != t2);
+
+ return NULL;
+}
+
+/*
+ * As per SAM_hdr_type, but returns a complete line of formatted text
+ * for a specific head type/ID combination. If ID is NULL then it returns
+ * the first line of the specified type.
+ *
+ * The returned string is malloced and should be freed by the calling
+ * function with free().
+ *
+ * Returns NULL if no type/ID is found.
+ */
+char *sam_hdr_find_line(SAM_hdr *hdr, char *type,
+ char *ID_key, char *ID_value) {
+ SAM_hdr_type *ty = sam_hdr_find(hdr, type, ID_key, ID_value);
+ kstring_t ks = KS_INITIALIZER;
+ SAM_hdr_tag *tag;
+ int r = 0;
+
+ if (!ty)
+ return NULL;
+
+ // Paste together the line from the hashed copy
+ r |= (kputc_('@', &ks) == EOF);
+ r |= (kputs(type, &ks) == EOF);
+ for (tag = ty->tag; tag; tag = tag->next) {
+ r |= (kputc_('\t', &ks) == EOF);
+ r |= (kputsn(tag->str, tag->len, &ks) == EOF);
+ }
+
+ if (r) {
+ KS_FREE(&ks);
+ return NULL;
+ }
+
+ return ks_str(&ks);
+}
+
+
+/*
+ * Looks for a specific key in a single sam header line.
+ * If prev is non-NULL it also fills this out with the previous tag, to
+ * permit use in key removal. *prev is set to NULL when the tag is the first
+ * key in the list. When a tag isn't found, prev (if non NULL) will be the last
+ * tag in the existing list.
+ *
+ * Returns the tag pointer on success
+ * NULL on failure
+ */
+SAM_hdr_tag *sam_hdr_find_key(SAM_hdr *sh,
+ SAM_hdr_type *type,
+ char *key,
+ SAM_hdr_tag **prev) {
+ SAM_hdr_tag *tag, *p = NULL;
+
+ for (tag = type->tag; tag; p = tag, tag = tag->next) {
+ if (tag->str[0] == key[0] && tag->str[1] == key[1]) {
+ if (prev)
+ *prev = p;
+ return tag;
+ }
+ }
+
+ if (prev)
+ *prev = p;
+
+ return NULL;
+}
+
+
+/*
+ * Adds or updates tag key,value pairs in a header line.
+ * Eg for adding M5 tags to @SQ lines or updating sort order for the
+ * @HD line (although use the sam_hdr_sort_order() function for
+ * HD manipulation, which is a wrapper around this funuction).
+ *
+ * Specify multiple key,value pairs ending in NULL.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int sam_hdr_update(SAM_hdr *hdr, SAM_hdr_type *type, ...) {
+ va_list ap;
+
+ va_start(ap, type);
+
+ for (;;) {
+ char *k, *v;
+ int idx;
+ SAM_hdr_tag *tag, *prev;
+
+ if (!(k = (char *)va_arg(ap, char *)))
+ break;
+ v = va_arg(ap, char *);
+
+ tag = sam_hdr_find_key(hdr, type, k, &prev);
+ if (!tag) {
+ if (!(tag = pool_alloc(hdr->tag_pool)))
+ return -1;
+ if (prev)
+ prev->next = tag;
+ else
+ type->tag = tag;
+
+ tag->next = NULL;
+ }
+
+ idx = ks_len(&hdr->text);
+ if (ksprintf(&hdr->text, "%2.2s:%s", k, v) < 0)
+ return -1;
+ tag->len = ks_len(&hdr->text) - idx;
+ tag->str = string_ndup(hdr->str_pool,
+ ks_str(&hdr->text) + idx,
+ tag->len);
+ if (!tag->str)
+ return -1;
+ }
+
+ va_end(ap);
+
+ return 0;
+}
+
+#define K(a) (((a)[0]<<8)|((a)[1]))
+
+/*
+ * Returns the sort order:
+ */
+enum sam_sort_order sam_hdr_sort_order(SAM_hdr *hdr) {
+ return hdr->sort_order;
+}
+
+static enum sam_sort_order sam_hdr_parse_sort_order(SAM_hdr *hdr) {
+ khint_t k;
+ enum sam_sort_order so;
+
+ so = ORDER_UNKNOWN;
+ k = kh_get(sam_hdr, hdr->h, K("HD"));
+ if (k != kh_end(hdr->h)) {
+ SAM_hdr_type *ty = kh_val(hdr->h, k);
+ SAM_hdr_tag *tag;
+ for (tag = ty->tag; tag; tag = tag->next) {
+ if (tag->str[0] == 'S' && tag->str[1] == 'O') {
+ if (strcmp(tag->str+3, "unsorted") == 0)
+ so = ORDER_UNSORTED;
+ else if (strcmp(tag->str+3, "queryname") == 0)
+ so = ORDER_NAME;
+ else if (strcmp(tag->str+3, "coordinate") == 0)
+ so = ORDER_COORD;
+ else if (strcmp(tag->str+3, "unknown") != 0)
+ fprintf(stderr, "Unknown sort order field: %s\n",
+ tag->str+3);
+ }
+ }
+ }
+
+ return so;
+}
+
+
+/*
+ * Reconstructs the kstring from the header hash table.
+ * Returns 0 on success
+ * -1 on failure
+ */
+int sam_hdr_rebuild(SAM_hdr *hdr) {
+ /* Order: HD then others */
+ kstring_t ks = KS_INITIALIZER;
+ khint_t k;
+
+
+ k = kh_get(sam_hdr, hdr->h, K("HD"));
+ if (k != kh_end(hdr->h)) {
+ SAM_hdr_type *ty = kh_val(hdr->h, k);
+ SAM_hdr_tag *tag;
+ if (EOF == kputs("@HD", &ks))
+ return -1;
+ for (tag = ty->tag; tag; tag = tag->next) {
+ if (EOF == kputc_('\t', &ks))
+ return -1;
+ if (EOF == kputsn_(tag->str, tag->len, &ks))
+ return -1;
+ }
+ if (EOF == kputc('\n', &ks))
+ return -1;
+ }
+
+ for (k = kh_begin(hdr->h); k != kh_end(hdr->h); k++) {
+ SAM_hdr_type *t1, *t2;
+
+ if (!kh_exist(hdr->h, k))
+ continue;
+
+ if (kh_key(hdr->h, k) == K("HD"))
+ continue;
+
+ t1 = t2 = kh_val(hdr->h, k);
+ do {
+ SAM_hdr_tag *tag;
+ char c[2];
+
+ if (EOF == kputc_('@', &ks))
+ return -1;
+ c[0] = kh_key(hdr->h, k)>>8;
+ c[1] = kh_key(hdr->h, k)&0xff;
+ if (EOF == kputsn_(c, 2, &ks))
+ return -1;
+ for (tag = t1->tag; tag; tag=tag->next) {
+ if (EOF == kputc_('\t', &ks))
+ return -1;
+ if (EOF == kputsn_(tag->str, tag->len, &ks))
+ return -1;
+ }
+ if (EOF == kputc('\n', &ks))
+ return -1;
+ t1 = t1->next;
+ } while (t1 != t2);
+ }
+
+ if (ks_str(&hdr->text))
+ KS_FREE(&hdr->text);
+
+ hdr->text = ks;
+
+ return 0;
+}
+
+
+/*
+ * Creates an empty SAM header, ready to be populated.
+ *
+ * Returns a SAM_hdr struct on success (free with sam_hdr_free())
+ * NULL on failure
+ */
+SAM_hdr *sam_hdr_new() {
+ SAM_hdr *sh = calloc(1, sizeof(*sh));
+
+ if (!sh)
+ return NULL;
+
+ sh->h = kh_init(sam_hdr);
+ if (!sh->h)
+ goto err;
+
+ sh->ID_cnt = 1;
+ sh->ref_count = 1;
+
+ sh->nref = 0;
+ sh->ref = NULL;
+ if (!(sh->ref_hash = kh_init(m_s2i)))
+ goto err;
+
+ sh->nrg = 0;
+ sh->rg = NULL;
+ if (!(sh->rg_hash = kh_init(m_s2i)))
+ goto err;
+
+ sh->npg = 0;
+ sh->pg = NULL;
+ sh->npg_end = sh->npg_end_alloc = 0;
+ sh->pg_end = NULL;
+ if (!(sh->pg_hash = kh_init(m_s2i)))
+ goto err;
+
+ KS_INIT(&sh->text);
+
+ if (!(sh->tag_pool = pool_create(sizeof(SAM_hdr_tag))))
+ goto err;
+
+ if (!(sh->type_pool = pool_create(sizeof(SAM_hdr_type))))
+ goto err;
+
+ if (!(sh->str_pool = string_pool_create(8192)))
+ goto err;
+
+ return sh;
+
+ err:
+ if (sh->h)
+ kh_destroy(sam_hdr, sh->h);
+
+ if (sh->tag_pool)
+ pool_destroy(sh->tag_pool);
+
+ if (sh->type_pool)
+ pool_destroy(sh->type_pool);
+
+ if (sh->str_pool)
+ string_pool_destroy(sh->str_pool);
+
+ free(sh);
+
+ return NULL;
+}
+
+
+/*
+ * Tokenises a SAM header into a hash table.
+ * Also extracts a few bits on specific data types, such as @RG lines.
+ *
+ * Returns a SAM_hdr struct on success (free with sam_hdr_free())
+ * NULL on failure
+ */
+SAM_hdr *sam_hdr_parse_(const char *hdr, int len) {
+ /* Make an empty SAM_hdr */
+ SAM_hdr *sh;
+
+ sh = sam_hdr_new();
+ if (NULL == sh) return NULL;
+
+ if (NULL == hdr) return sh; // empty header is permitted
+
+ /* Parse the header, line by line */
+ if (-1 == sam_hdr_add_lines(sh, hdr, len)) {
+ sam_hdr_free(sh);
+ return NULL;
+ }
+
+ /* Obtain sort order */
+ sh->sort_order = sam_hdr_parse_sort_order(sh);
+
+ //sam_hdr_dump(sh);
+ //sam_hdr_add(sh, "RG", "ID", "foo", "SM", "bar", NULL);
+ //sam_hdr_rebuild(sh);
+ //printf(">>%s<<", ks_str(sh->text));
+
+ //parse_references(sh);
+ //parse_read_groups(sh);
+
+ sam_hdr_link_pg(sh);
+ //sam_hdr_dump(sh);
+
+ return sh;
+}
+
+/*
+ * Produces a duplicate copy of hdr and returns it.
+ * Returns NULL on failure
+ */
+SAM_hdr *sam_hdr_dup(SAM_hdr *hdr) {
+ if (-1 == sam_hdr_rebuild(hdr))
+ return NULL;
+
+ return sam_hdr_parse_(sam_hdr_str(hdr), sam_hdr_length(hdr));
+}
+
+/*! Increments a reference count on hdr.
+ *
+ * This permits multiple files to share the same header, all calling
+ * sam_hdr_free when done, without causing errors for other open files.
+ */
+void sam_hdr_incr_ref(SAM_hdr *hdr) {
+ hdr->ref_count++;
+}
+
+/*! Increments a reference count on hdr.
+ *
+ * This permits multiple files to share the same header, all calling
+ * sam_hdr_free when done, without causing errors for other open files.
+ *
+ * If the reference count hits zero then the header is automatically
+ * freed. This makes it a synonym for sam_hdr_free().
+ */
+void sam_hdr_decr_ref(SAM_hdr *hdr) {
+ sam_hdr_free(hdr);
+}
+
+/*! Deallocates all storage used by a SAM_hdr struct.
+ *
+ * This also decrements the header reference count. If after decrementing
+ * it is still non-zero then the header is assumed to be in use by another
+ * caller and the free is not done.
+ *
+ * This is a synonym for sam_hdr_dec_ref().
+ */
+void sam_hdr_free(SAM_hdr *hdr) {
+ if (!hdr)
+ return;
+
+ if (--hdr->ref_count > 0)
+ return;
+
+ if (ks_str(&hdr->text))
+ KS_FREE(&hdr->text);
+
+ if (hdr->h)
+ kh_destroy(sam_hdr, hdr->h);
+
+ if (hdr->ref_hash)
+ kh_destroy(m_s2i, hdr->ref_hash);
+
+ if (hdr->ref) {
+ int i;
+ for (i = 0; i < hdr->nref; i++)
+ if (hdr->ref[i].name)
+ free(hdr->ref[i].name);
+ free(hdr->ref);
+ }
+
+ if (hdr->rg_hash)
+ kh_destroy(m_s2i, hdr->rg_hash);
+
+ if (hdr->rg) {
+ int i;
+ for (i = 0; i < hdr->nrg; i++)
+ if (hdr->rg[i].name)
+ free(hdr->rg[i].name);
+ free(hdr->rg);
+ }
+
+ if (hdr->pg_hash)
+ kh_destroy(m_s2i, hdr->pg_hash);
+
+ if (hdr->pg) {
+ int i;
+ for (i = 0; i < hdr->npg; i++)
+ if (hdr->pg[i].name)
+ free(hdr->pg[i].name);
+ free(hdr->pg);
+ }
+
+ if (hdr->pg_end)
+ free(hdr->pg_end);
+
+ if (hdr->type_pool)
+ pool_destroy(hdr->type_pool);
+
+ if (hdr->tag_pool)
+ pool_destroy(hdr->tag_pool);
+
+ if (hdr->str_pool)
+ string_pool_destroy(hdr->str_pool);
+
+ free(hdr);
+}
+
+int sam_hdr_length(SAM_hdr *hdr) {
+ return ks_len(&hdr->text);
+}
+
+char *sam_hdr_str(SAM_hdr *hdr) {
+ return ks_str(&hdr->text);
+}
+
+/*
+ * Looks up a reference sequence by name and returns the numerical ID.
+ * Returns -1 if unknown reference.
+ */
+int sam_hdr_name2ref(SAM_hdr *hdr, const char *ref) {
+ khint_t k = kh_get(m_s2i, hdr->ref_hash, ref);
+ return k == kh_end(hdr->ref_hash) ? -1 : kh_val(hdr->ref_hash, k);
+}
+
+/*
+ * Looks up a read-group by name and returns a pointer to the start of the
+ * associated tag list.
+ *
+ * Returns NULL on failure
+ */
+SAM_RG *sam_hdr_find_rg(SAM_hdr *hdr, const char *rg) {
+ khint_t k = kh_get(m_s2i, hdr->rg_hash, rg);
+ return k == kh_end(hdr->rg_hash)
+ ? NULL
+ : &hdr->rg[kh_val(hdr->rg_hash, k)];
+}
+
+
+/*
+ * Fixes any PP links in @PG headers.
+ * If the entries are in order then this doesn't need doing, but incase
+ * our header is out of order this goes through the sh->pg[] array
+ * setting the prev_id field.
+ *
+ * Note we can have multiple complete chains. This code should identify the
+ * tails of these chains as these are the entries we have to link to in
+ * subsequent PP records.
+ *
+ * Returns 0 on sucess
+ * -1 on failure (indicating broken PG/PP records)
+ */
+int sam_hdr_link_pg(SAM_hdr *hdr) {
+ int i, j, ret = 0;
+
+ hdr->npg_end_alloc = hdr->npg;
+ hdr->pg_end = realloc(hdr->pg_end, hdr->npg * sizeof(*hdr->pg_end));
+ if (!hdr->pg_end)
+ return -1;
+
+ for (i = 0; i < hdr->npg; i++)
+ hdr->pg_end[i] = i;
+
+ for (i = 0; i < hdr->npg; i++) {
+ khint_t k;
+ SAM_hdr_tag *tag;
+ char tmp;
+
+ for (tag = hdr->pg[i].tag; tag; tag = tag->next) {
+ if (tag->str[0] == 'P' && tag->str[1] == 'P')
+ break;
+ }
+ if (!tag) {
+ /* Chain start points */
+ continue;
+ }
+
+ tmp = tag->str[tag->len]; tag->str[tag->len] = 0;
+ k = kh_get(m_s2i, hdr->pg_hash, tag->str+3);
+ tag->str[tag->len] = tmp;
+
+ if (k == kh_end(hdr->pg_hash)) {
+ ret = -1;
+ continue;
+ }
+
+ hdr->pg[i].prev_id = hdr->pg[kh_val(hdr->pg_hash, k)].id;
+ hdr->pg_end[kh_val(hdr->pg_hash, k)] = -1;
+ }
+
+ for (i = j = 0; i < hdr->npg; i++) {
+ if (hdr->pg_end[i] != -1)
+ hdr->pg_end[j++] = hdr->pg_end[i];
+ }
+ hdr->npg_end = j;
+
+ return ret;
+}
+
+/*
+ * Returns a unique ID from a base name.
+ *
+ * The value returned is valid until the next call to
+ * this function.
+ */
+const char *sam_hdr_PG_ID(SAM_hdr *sh, const char *name) {
+ khint_t k = kh_get(m_s2i, sh->pg_hash, name);
+ if (k == kh_end(sh->pg_hash))
+ return name;
+
+ do {
+ sprintf(sh->ID_buf, "%.1000s.%d", name, sh->ID_cnt++);
+ k = kh_get(m_s2i, sh->pg_hash, sh->ID_buf);
+ } while (k != kh_end(sh->pg_hash));
+
+ return sh->ID_buf;
+}
+
+/*
+ * Add an @PG line.
+ *
+ * If we wish complete control over this use sam_hdr_add() directly. This
+ * function uses that, but attempts to do a lot of tedious house work for
+ * you too.
+ *
+ * - It will generate a suitable ID if the supplied one clashes.
+ * - It will generate multiple @PG records if we have multiple PG chains.
+ *
+ * Call it as per sam_hdr_add() with a series of key,value pairs ending
+ * in NULL.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int sam_hdr_add_PG(SAM_hdr *sh, const char *name, ...) {
+ va_list args;
+
+ if (sh->npg_end) {
+ /* Copy ends array to avoid us looping while modifying it */
+ int *end = malloc(sh->npg_end * sizeof(int));
+ int i, nends = sh->npg_end;
+
+ if (!end)
+ return -1;
+
+ memcpy(end, sh->pg_end, nends * sizeof(*end));
+
+ for (i = 0; i < nends; i++) {
+ va_start(args, name);
+ if (-1 == sam_hdr_vadd(sh, "PG", args,
+ "ID", sam_hdr_PG_ID(sh, name),
+ "PN", name,
+ "PP", sh->pg[end[i]].name,
+ NULL)) {
+ free(end);
+ return -1;
+ }
+ va_end(args);
+ }
+
+ free(end);
+ } else {
+ va_start(args, name);
+ if (-1 == sam_hdr_vadd(sh, "PG", args,
+ "ID", sam_hdr_PG_ID(sh, name),
+ "PN", name,
+ NULL))
+ return -1;
+ va_end(args);
+ }
+
+ //sam_hdr_dump(sh);
+
+ return 0;
+}
+
+/*
+ * A function to help with construction of CL tags in @PG records.
+ * Takes an argc, argv pair and returns a single space-separated string.
+ * This string should be deallocated by the calling function.
+ *
+ * Returns malloced char * on success
+ * NULL on failure
+ */
+char *stringify_argv(int argc, char *argv[]) {
+ char *str, *cp;
+ size_t nbytes = 1;
+ int i, j;
+
+ /* Allocate */
+ for (i = 0; i < argc; i++) {
+ nbytes += strlen(argv[i]) + 1;
+ }
+ if (!(str = malloc(nbytes)))
+ return NULL;
+
+ /* Copy */
+ cp = str;
+ for (i = 0; i < argc; i++) {
+ j = 0;
+ while (argv[i][j]) {
+ if (argv[i][j] == '\t')
+ *cp++ = ' ';
+ else
+ *cp++ = argv[i][j];
+ j++;
+ }
+ *cp++ = ' ';
+ }
+ *cp++ = 0;
+
+ return str;
+}
--- /dev/null
+/*
+Copyright (c) 2013-2014 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*! \file
+ * SAM header parsing.
+ *
+ * These functions can be shared between SAM, BAM and CRAM file
+ * formats as all three internally use the same string encoding for
+ * header fields.
+ */
+
+/*
+ * TODO.
+ *
+ * - Sort order (parse to struct, enum type, updating funcs)
+ * - Removal of lines.
+ * - Updating of lines
+ */
+
+#ifndef _SAM_HDR_H_
+#define _SAM_HDR_H_
+
+#include <stdarg.h>
+
+#include "cram/string_alloc.h"
+#include "cram/pooled_alloc.h"
+
+#include "htslib/khash.h"
+#include "htslib/kstring.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+// For structure assignment. Eg kstring_t s = KS_INITIALIZER;
+#define KS_INITIALIZER {0,0,0}
+
+// For initialisation elsewhere. Eg KS_INIT(x->str);
+#define KS_INIT(ks) ((ks)->l = 0, (ks)->m = 0, (ks)->s = NULL)
+
+// Frees the string subfield only. Assumes 's' itself is static.
+#define KS_FREE(ks) do { if ((ks)->s) free((ks)->s); } while(0)
+
+/*
+ * Proposed new SAM header parsing
+
+1 @SQ ID:foo LN:100
+2 @SQ ID:bar LN:200
+3 @SQ ID:ram LN:300 UR:xyz
+4 @RG ID:r ...
+5 @RG ID:s ...
+
+Hash table for 2-char @keys without dup entries.
+If dup lines, we form a circular linked list. Ie hash keys = {RG, SQ}.
+
+HASH("SQ")--\
+ |
+ (3) <-> 1 <-> 2 <-> 3 <-> (1)
+
+HASH("RG")--\
+ |
+ (5) <-> 4 <-> 5 <-> (4)
+
+Items stored in the hash values also form their own linked lists:
+Ie SQ->ID(foo)->LN(100)
+ SQ->ID(bar)->LN(200)
+ SQ->ID(ram)->LN(300)->UR(xyz)
+ RG->ID(r)
+ */
+
+/*! A single key:value pair on a header line
+ *
+ * These form a linked list and hold strings. The strings are
+ * allocated from a string_alloc_t pool referenced in the master
+ * SAM_hdr structure. Do not attempt to free, malloc or manipulate
+ * these strings directly.
+ */
+typedef struct SAM_hdr_tag_s {
+ struct SAM_hdr_tag_s *next;
+ char *str;
+ int len;
+} SAM_hdr_tag;
+
+/*! The parsed version of the SAM header string.
+ *
+ * Each header type (SQ, RG, HD, etc) points to its own SAM_hdr_type
+ * struct via the main hash table h in the SAM_hdr struct.
+ *
+ * These in turn consist of circular bi-directional linked lists (ie
+ * rings) to hold the multiple instances of the same header type
+ * code. For example if we have 5 \@SQ lines the primary hash table
+ * will key on \@SQ pointing to the first SAM_hdr_type and that in turn
+ * will be part of a ring of 5 elements.
+ *
+ * For each SAM_hdr_type structure we also point to a SAM_hdr_tag
+ * structure which holds the tokenised attributes; the tab separated
+ * key:value pairs per line.
+ */
+typedef struct SAM_hdr_item_s {
+ struct SAM_hdr_item_s *next; // cirular
+ struct SAM_hdr_item_s *prev;
+ SAM_hdr_tag *tag; // first tag
+ int order; // 0 upwards
+} SAM_hdr_type;
+
+/*! Parsed \@SQ lines */
+typedef struct {
+ char *name;
+ uint32_t len;
+ SAM_hdr_type *ty;
+ SAM_hdr_tag *tag;
+} SAM_SQ;
+
+/*! Parsed \@RG lines */
+typedef struct {
+ char *name;
+ SAM_hdr_type *ty;
+ SAM_hdr_tag *tag;
+ int name_len;
+ int id; // numerical ID
+} SAM_RG;
+
+/*! Parsed \@PG lines */
+typedef struct {
+ char *name;
+ SAM_hdr_type *ty;
+ SAM_hdr_tag *tag;
+ int name_len;
+ int id; // numerical ID
+ int prev_id; // -1 if none
+} SAM_PG;
+
+/*! Sort order parsed from @HD line */
+enum sam_sort_order {
+ ORDER_UNKNOWN =-1,
+ ORDER_UNSORTED = 0,
+ ORDER_NAME = 1,
+ ORDER_COORD = 2,
+ //ORDER_COLLATE = 3 // maybe one day!
+};
+
+KHASH_MAP_INIT_INT(sam_hdr, SAM_hdr_type*)
+KHASH_MAP_INIT_STR(m_s2i, int)
+
+/*! Primary structure for header manipulation
+ *
+ * The initial header text is held in the text kstring_t, but is also
+ * parsed out into SQ, RG and PG arrays. These have a hash table
+ * associated with each to allow lookup by ID or SN fields instead of
+ * their numeric array indices. Additionally PG has an array to hold
+ * the linked list start points (the last in a PP chain).
+ *
+ * Use the appropriate sam_hdr_* functions to edit the header, and
+ * call sam_hdr_rebuild() any time the textual form needs to be
+ * updated again.
+ */
+typedef struct {
+ kstring_t text; //!< concatenated text, indexed by SAM_hdr_tag
+ khash_t(sam_hdr) *h;
+ string_alloc_t *str_pool; //!< Pool of SAM_hdr_tag->str strings
+ pool_alloc_t *type_pool;//!< Pool of SAM_hdr_type structs
+ pool_alloc_t *tag_pool; //!< Pool of SAM_hdr_tag structs
+
+ // @SQ lines / references
+ int nref; //!< Number of \@SQ lines
+ SAM_SQ *ref; //!< Array of parsed \@SQ lines
+ khash_t(m_s2i) *ref_hash; //!< Maps SQ SN field to sq[] index
+
+ // @RG lines / read-groups
+ int nrg; //!< Number of \@RG lines
+ SAM_RG *rg; //!< Array of parsed \@RG lines
+ khash_t(m_s2i) *rg_hash; //!< Maps RG ID field to rg[] index
+
+ // @PG lines / programs
+ int npg; //!< Number of \@PG lines
+ int npg_end; //!< Number of terminating \@PG lines
+ int npg_end_alloc; //!< Size of pg_end field
+ SAM_PG *pg; //!< Array of parsed \@PG lines
+ khash_t(m_s2i) *pg_hash; //!< Maps PG ID field to pg[] index
+ int *pg_end; //!< \@PG chain termination IDs
+
+ // @HD data
+ enum sam_sort_order sort_order; //!< @HD SO: field
+
+ // @cond internal
+ char ID_buf[1024]; // temporary buffer
+ int ID_cnt;
+ int ref_count; // number of uses of this SAM_hdr
+ // @endcond
+} SAM_hdr;
+
+/*! Creates an empty SAM header, ready to be populated.
+ *
+ * @return
+ * Returns a SAM_hdr struct on success (free with sam_hdr_free())
+ * NULL on failure
+ */
+SAM_hdr *sam_hdr_new(void);
+
+/*! Tokenises a SAM header into a hash table.
+ *
+ * Also extracts a few bits on specific data types, such as @RG lines.
+ *
+ * @return
+ * Returns a SAM_hdr struct on success (free with sam_hdr_free());
+ * NULL on failure
+ */
+SAM_hdr *sam_hdr_parse_(const char *hdr, int len);
+
+
+/*! Produces a duplicate copy of hdr and returns it.
+ * @return
+ * Returns NULL on failure
+ */
+SAM_hdr *sam_hdr_dup(SAM_hdr *hdr);
+
+
+/*! Increments a reference count on hdr.
+ *
+ * This permits multiple files to share the same header, all calling
+ * sam_hdr_free when done, without causing errors for other open files.
+ */
+void sam_hdr_incr_ref(SAM_hdr *hdr);
+
+
+/*! Increments a reference count on hdr.
+ *
+ * This permits multiple files to share the same header, all calling
+ * sam_hdr_free when done, without causing errors for other open files.
+ *
+ * If the reference count hits zero then the header is automatically
+ * freed. This makes it a synonym for sam_hdr_free().
+ */
+void sam_hdr_decr_ref(SAM_hdr *hdr);
+
+
+/*! Deallocates all storage used by a SAM_hdr struct.
+ *
+ * This also decrements the header reference count. If after decrementing
+ * it is still non-zero then the header is assumed to be in use by another
+ * caller and the free is not done.
+ *
+ * This is a synonym for sam_hdr_dec_ref().
+ */
+void sam_hdr_free(SAM_hdr *hdr);
+
+/*! Returns the current length of the SAM_hdr in text form.
+ *
+ * Call sam_hdr_rebuild() first if editing has taken place.
+ */
+int sam_hdr_length(SAM_hdr *hdr);
+
+/*! Returns the string form of the SAM_hdr.
+ *
+ * Call sam_hdr_rebuild() first if editing has taken place.
+ */
+char *sam_hdr_str(SAM_hdr *hdr);
+
+/*! Appends a formatted line to an existing SAM header.
+ *
+ * Line is a full SAM header record, eg "@SQ\tSN:foo\tLN:100", with
+ * optional new-line. If it contains more than 1 line then multiple lines
+ * will be added in order.
+ *
+ * Input text is of maximum length len or as terminated earlier by a NUL.
+ * Len may be 0 if unknown, in which case lines must be NUL-terminated.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int sam_hdr_add_lines(SAM_hdr *sh, const char *lines, int len);
+
+/*! Adds a single line to a SAM header.
+ *
+ * Specify type and one or more key,value pairs, ending with the NULL key.
+ * Eg. sam_hdr_add(h, "SQ", "ID", "foo", "LN", "100", NULL).
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int sam_hdr_add(SAM_hdr *sh, const char *type, ...);
+
+/*! Adds a single line to a SAM header.
+ *
+ * This is much like sam_hdr_add() but with the additional va_list
+ * argument. This is followed by specifying type and one or more
+ * key,value pairs, ending with the NULL key.
+ *
+ * Eg. sam_hdr_vadd(h, "SQ", args, "ID", "foo", "LN", "100", NULL).
+ *
+ * The purpose of the additional va_list parameter is to permit other
+ * varargs functions to call this while including their own additional
+ * parameters; an example is in sam_hdr_add_PG().
+ *
+ * Note: this function invokes va_arg at least once, making the value
+ * of ap indeterminate after the return. The caller should call
+ * va_start/va_end before/after calling this function or use va_copy.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int sam_hdr_vadd(SAM_hdr *sh, const char *type, va_list ap, ...);
+
+/*!
+ * @return
+ * Returns the first header item matching 'type'. If ID is non-NULL it checks
+ * for the tag ID: and compares against the specified ID.
+ *
+ * Returns NULL if no type/ID is found
+ */
+SAM_hdr_type *sam_hdr_find(SAM_hdr *hdr, char *type,
+ char *ID_key, char *ID_value);
+
+/*!
+ *
+ * As per SAM_hdr_type, but returns a complete line of formatted text
+ * for a specific head type/ID combination. If ID is NULL then it returns
+ * the first line of the specified type.
+ *
+ * The returned string is malloced and should be freed by the calling
+ * function with free().
+ *
+ * @return
+ * Returns NULL if no type/ID is found.
+ */
+char *sam_hdr_find_line(SAM_hdr *hdr, char *type,
+ char *ID_key, char *ID_value);
+
+/*! Looks for a specific key in a single sam header line.
+ *
+ * If prev is non-NULL it also fills this out with the previous tag, to
+ * permit use in key removal. *prev is set to NULL when the tag is the first
+ * key in the list. When a tag isn't found, prev (if non NULL) will be the last
+ * tag in the existing list.
+ *
+ * @return
+ * Returns the tag pointer on success;
+ * NULL on failure
+ */
+SAM_hdr_tag *sam_hdr_find_key(SAM_hdr *sh,
+ SAM_hdr_type *type,
+ char *key,
+ SAM_hdr_tag **prev);
+
+/*! Adds or updates tag key,value pairs in a header line.
+ *
+ * Eg for adding M5 tags to @SQ lines or updating sort order for the
+ * @HD line (although use the sam_hdr_sort_order() function for
+ * HD manipulation, which is a wrapper around this funuction).
+ *
+ * Specify multiple key,value pairs ending in NULL.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int sam_hdr_update(SAM_hdr *hdr, SAM_hdr_type *type, ...);
+
+/*! Returns the sort order from the @HD SO: field */
+enum sam_sort_order sam_hdr_sort_order(SAM_hdr *hdr);
+
+/*! Reconstructs the kstring from the header hash table.
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int sam_hdr_rebuild(SAM_hdr *hdr);
+
+/*! Looks up a reference sequence by name and returns the numerical ID.
+ * @return
+ * Returns -1 if unknown reference.
+ */
+int sam_hdr_name2ref(SAM_hdr *hdr, const char *ref);
+
+/*! Looks up a read-group by name and returns a pointer to the start of the
+ * associated tag list.
+ *
+ * @return
+ * Returns NULL on failure
+ */
+SAM_RG *sam_hdr_find_rg(SAM_hdr *hdr, const char *rg);
+
+/*! Fixes any PP links in @PG headers.
+ *
+ * If the entries are in order then this doesn't need doing, but incase
+ * our header is out of order this goes through the sh->pg[] array
+ * setting the prev_id field.
+ *
+ * @return
+ * Returns 0 on sucess;
+ * -1 on failure (indicating broken PG/PP records)
+ */
+int sam_hdr_link_pg(SAM_hdr *hdr);
+
+
+/*! Add an @PG line.
+ *
+ * If we wish complete control over this use sam_hdr_add() directly. This
+ * function uses that, but attempts to do a lot of tedious house work for
+ * you too.
+ *
+ * - It will generate a suitable ID if the supplied one clashes.
+ * - It will generate multiple @PG records if we have multiple PG chains.
+ *
+ * Call it as per sam_hdr_add() with a series of key,value pairs ending
+ * in NULL.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int sam_hdr_add_PG(SAM_hdr *sh, const char *name, ...);
+
+/*!
+ * A function to help with construction of CL tags in @PG records.
+ * Takes an argc, argv pair and returns a single space-separated string.
+ * This string should be deallocated by the calling function.
+ *
+ * @return
+ * Returns malloced char * on success;
+ * NULL on failure
+ */
+char *stringify_argv(int argc, char *argv[]);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _SAM_HDR_H_ */
--- /dev/null
+/*
+Copyright (c) 2010 Genome Research Ltd.
+Author: Andrew Whitwham <aw7@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+
+/*
+ A pooled string allocator intended to cut down on the
+ memory overhead of many small string allocations.
+
+ Andrew Whitwham, September 2010.
+*/
+
+#include <config.h>
+
+#include <string.h>
+#include <stdlib.h>
+#include <stdio.h>
+
+#include "string_alloc.h"
+
+#define MIN_STR_SIZE 1024
+
+
+/* creates the string pool. max_length is the initial size
+ a single string can be. Tha max_length can grow as
+ needed */
+
+string_alloc_t *string_pool_create(size_t max_length) {
+ string_alloc_t *a_str;
+
+ if (NULL == (a_str = (string_alloc_t *)malloc(sizeof(*a_str)))) {
+ return NULL;
+ }
+
+ if (max_length < MIN_STR_SIZE) max_length = MIN_STR_SIZE;
+
+ a_str->nstrings = 0;
+ a_str->max_length = max_length;
+ a_str->strings = NULL;
+
+ return a_str;
+}
+
+
+/* internal function to do the actual memory allocation */
+
+static string_t *new_string_pool(string_alloc_t *a_str) {
+ string_t *str;
+
+ str = realloc(a_str->strings, (a_str->nstrings + 1) * sizeof(*a_str->strings));
+
+ if (NULL == str) return NULL;
+
+ a_str->strings = str;
+ str = &a_str->strings[a_str->nstrings];
+
+ str->str = malloc(a_str->max_length);;
+
+ if (NULL == str->str) return NULL;
+
+ str->used = 0;
+ a_str->nstrings++;
+
+ return str;
+}
+
+
+/* free allocated memory */
+
+void string_pool_destroy(string_alloc_t *a_str) {
+ size_t i;
+
+ for (i = 0; i < a_str->nstrings; i++) {
+ free(a_str->strings[i].str);
+ }
+
+ free(a_str->strings);
+ free(a_str);
+}
+
+
+/* allocate space for a string */
+
+char *string_alloc(string_alloc_t *a_str, size_t length) {
+ string_t *str;
+ char *ret;
+
+ if (length <= 0) return NULL;
+
+ // add to last string pool if we have space
+ if (a_str->nstrings) {
+ str = &a_str->strings[a_str->nstrings - 1];
+
+ if (str->used + length < a_str->max_length) {
+ ret = str->str + str->used;
+ str->used += length;
+ return ret;
+ }
+ }
+
+ // increase the max length if needs be
+ if (length > a_str->max_length) a_str->max_length = length;
+
+ // need a new string pool
+ str = new_string_pool(a_str);
+
+ if (NULL == str) return NULL;
+
+ str->used = length;
+ return str->str;
+}
+
+
+/* equivalent to strdup */
+
+char *string_dup(string_alloc_t *a_str, char *instr) {
+ return string_ndup(a_str, instr, strlen(instr));
+}
+
+char *string_ndup(string_alloc_t *a_str, char *instr, size_t len) {
+ char *str = string_alloc(a_str, len + 1);
+
+ if (NULL == str) return NULL;
+
+ strncpy(str, instr, len);
+ str[len] = 0;
+
+ return str;
+}
--- /dev/null
+/*
+Copyright (c) 2010 Genome Research Ltd.
+Author: Andrew Whitwham <aw7@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _STRING_ALLOC_H_
+#define _STRING_ALLOC_H_
+
+#include <stdlib.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*
+ * A pooled string allocator intended to cut down on the
+ * memory overhead of many small string allocations.
+ *
+ * Andrew Whitwham, September 2010.
+ */
+
+typedef struct {
+ char *str;
+ size_t used;
+} string_t;
+
+typedef struct {
+ size_t max_length;
+ size_t nstrings;
+ string_t *strings;
+} string_alloc_t;
+
+string_alloc_t *string_pool_create(size_t max_length);
+void string_pool_destroy(string_alloc_t *a_str);
+char *string_alloc(string_alloc_t *a_str, size_t length);
+char *string_dup(string_alloc_t *a_str, char *instr);
+char *string_ndup(string_alloc_t *a_str, char *instr, size_t len);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/*
+Copyright (c) 2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <stdlib.h>
+
+#include <signal.h>
+#include <errno.h>
+#include <stdio.h>
+#include <string.h>
+#include <sys/time.h>
+#include <assert.h>
+
+#include "cram/thread_pool.h"
+
+//#define DEBUG
+//#define DEBUG_TIME
+
+#define IN_ORDER
+
+#ifdef DEBUG
+static int worker_id(t_pool *p) {
+ int i;
+ pthread_t s = pthread_self();
+ for (i = 0; i < p->tsize; i++) {
+ if (pthread_equal(s, p->t[i].tid))
+ return i;
+ }
+ return -1;
+}
+#endif
+
+/* ----------------------------------------------------------------------------
+ * A queue to hold results from the thread pool.
+ *
+ * Each thread pool may have jobs of multiple types being queued up and
+ * interleaved, so we allow several results queue per pool.
+ *
+ * The jobs themselves are expected to push their results onto their
+ * appropriate results queue.
+ */
+
+/*
+ * Adds a result to the end of the result queue.
+ *
+ * Returns 0 on success;
+ * -1 on failure
+ */
+static int t_pool_add_result(t_pool_job *j, void *data) {
+ t_results_queue *q = j->q;
+ t_pool_result *r;
+
+#ifdef DEBUG
+ fprintf(stderr, "%d: Adding resulting to queue %p, serial %d\n",
+ worker_id(j->p), q, j->serial);
+#endif
+
+ /* No results queue is fine if we don't want any results back */
+ if (!q)
+ return 0;
+
+ if (!(r = malloc(sizeof(*r))))
+ return -1;
+
+ r->next = NULL;
+ r->data = data;
+ r->serial = j->serial;
+
+ pthread_mutex_lock(&q->result_m);
+ if (q->result_tail) {
+ q->result_tail->next = r;
+ q->result_tail = r;
+ } else {
+ q->result_head = q->result_tail = r;
+ }
+ q->queue_len++;
+ q->pending--;
+
+#ifdef DEBUG
+ fprintf(stderr, "%d: Broadcasting result_avail (id %d)\n",
+ worker_id(j->p), r->serial);
+#endif
+ pthread_cond_signal(&q->result_avail_c);
+#ifdef DEBUG
+ fprintf(stderr, "%d: Broadcast complete\n", worker_id(j->p));
+#endif
+
+ pthread_mutex_unlock(&q->result_m);
+
+ return 0;
+}
+
+/* Core of t_pool_next_result() */
+static t_pool_result *t_pool_next_result_locked(t_results_queue *q) {
+ t_pool_result *r, *last;
+
+ for (last = NULL, r = q->result_head; r; last = r, r = r->next) {
+ if (r->serial == q->next_serial)
+ break;
+ }
+
+ if (r) {
+ if (q->result_head == r)
+ q->result_head = r->next;
+ else
+ last->next = r->next;
+
+ if (q->result_tail == r)
+ q->result_tail = last;
+
+ if (!q->result_head)
+ q->result_tail = NULL;
+
+ q->next_serial++;
+ q->queue_len--;
+ }
+
+ return r;
+}
+
+/*
+ * Pulls a result off the head of the result queue. Caller should
+ * free it (and any internals as appropriate) after use. This doesn't
+ * wait for a result to be present.
+ *
+ * Results will be returned in strict order.
+ *
+ * Returns t_pool_result pointer if a result is ready.
+ * NULL if not.
+ */
+t_pool_result *t_pool_next_result(t_results_queue *q) {
+ t_pool_result *r;
+
+#ifdef DEBUG
+ fprintf(stderr, "Requesting next result on queue %p\n", q);
+#endif
+
+ pthread_mutex_lock(&q->result_m);
+ r = t_pool_next_result_locked(q);
+ pthread_mutex_unlock(&q->result_m);
+
+#ifdef DEBUG
+ fprintf(stderr, "(q=%p) Found %p\n", q, r);
+#endif
+
+ return r;
+}
+
+t_pool_result *t_pool_next_result_wait(t_results_queue *q) {
+ t_pool_result *r;
+
+#ifdef DEBUG
+ fprintf(stderr, "Waiting for result %d...\n", q->next_serial);
+#endif
+
+ pthread_mutex_lock(&q->result_m);
+ while (!(r = t_pool_next_result_locked(q))) {
+ /* Possible race here now avoided via _locked() call, but incase... */
+ struct timeval now;
+ struct timespec timeout;
+
+ gettimeofday(&now, NULL);
+ timeout.tv_sec = now.tv_sec + 10;
+ timeout.tv_nsec = now.tv_usec * 1000;
+
+ pthread_cond_timedwait(&q->result_avail_c, &q->result_m, &timeout);
+ }
+ pthread_mutex_unlock(&q->result_m);
+
+ return r;
+}
+
+/*
+ * Returns true if there are no items on the finished results queue and
+ * also none still pending.
+ */
+int t_pool_results_queue_empty(t_results_queue *q) {
+ int empty;
+
+ pthread_mutex_lock(&q->result_m);
+ empty = q->queue_len == 0 && q->pending == 0;
+ pthread_mutex_unlock(&q->result_m);
+
+ return empty;
+}
+
+
+/*
+ * Returns the number of completed jobs on the results queue.
+ */
+int t_pool_results_queue_len(t_results_queue *q) {
+ int len;
+
+ pthread_mutex_lock(&q->result_m);
+ len = q->queue_len;
+ pthread_mutex_unlock(&q->result_m);
+
+ return len;
+}
+
+int t_pool_results_queue_sz(t_results_queue *q) {
+ int len;
+
+ pthread_mutex_lock(&q->result_m);
+ len = q->queue_len + q->pending;
+ pthread_mutex_unlock(&q->result_m);
+
+ return len;
+}
+
+/*
+ * Frees a result 'r' and if free_data is true also frees
+ * the internal r->data result too.
+ */
+void t_pool_delete_result(t_pool_result *r, int free_data) {
+ if (!r)
+ return;
+
+ if (free_data && r->data)
+ free(r->data);
+
+ free(r);
+}
+
+/*
+ * Initialises a results queue.
+ *
+ * Results queue pointer on success;
+ * NULL on failure
+ */
+t_results_queue *t_results_queue_init(void) {
+ t_results_queue *q = malloc(sizeof(*q));
+
+ pthread_mutex_init(&q->result_m, NULL);
+ pthread_cond_init(&q->result_avail_c, NULL);
+
+ q->result_head = NULL;
+ q->result_tail = NULL;
+ q->next_serial = 0;
+ q->curr_serial = 0;
+ q->queue_len = 0;
+ q->pending = 0;
+
+ return q;
+}
+
+/* Deallocates memory for a results queue */
+void t_results_queue_destroy(t_results_queue *q) {
+#ifdef DEBUG
+ fprintf(stderr, "Destroying results queue %p\n", q);
+#endif
+
+ if (!q)
+ return;
+
+ pthread_mutex_destroy(&q->result_m);
+ pthread_cond_destroy(&q->result_avail_c);
+
+ memset(q, 0xbb, sizeof(*q));
+ free(q);
+
+#ifdef DEBUG
+ fprintf(stderr, "Destroyed results queue %p\n", q);
+#endif
+}
+
+/* ----------------------------------------------------------------------------
+ * The thread pool.
+ */
+
+#define TDIFF(t2,t1) ((t2.tv_sec-t1.tv_sec)*1000000 + t2.tv_usec-t1.tv_usec)
+
+/*
+ * A worker thread.
+ *
+ * Each thread waits for the pool to be non-empty.
+ * As soon as this applies, one of them succeeds in getting the lock
+ * and then executes the job.
+ */
+static void *t_pool_worker(void *arg) {
+ t_pool_worker_t *w = (t_pool_worker_t *)arg;
+ t_pool *p = w->p;
+ t_pool_job *j;
+#ifdef DEBUG_TIME
+ struct timeval t1, t2, t3;
+#endif
+
+ for (;;) {
+ // Pop an item off the pool queue
+#ifdef DEBUG_TIME
+ gettimeofday(&t1, NULL);
+#endif
+
+ pthread_mutex_lock(&p->pool_m);
+
+#ifdef DEBUG_TIME
+ gettimeofday(&t2, NULL);
+ p->wait_time += TDIFF(t2,t1);
+ w->wait_time += TDIFF(t2,t1);
+#endif
+
+ // If there is something on the job list and a higher priority
+ // thread waiting, let it handle this instead.
+// while (p->head && p->t_stack_top != -1 && p->t_stack_top < w->idx) {
+// pthread_mutex_unlock(&p->pool_m);
+// pthread_cond_signal(&p->t[p->t_stack_top].pending_c);
+// pthread_mutex_lock(&p->pool_m);
+// }
+
+ while (!p->head && !p->shutdown) {
+ p->nwaiting++;
+
+ if (p->njobs == 0)
+ pthread_cond_signal(&p->empty_c);
+#ifdef DEBUG_TIME
+ gettimeofday(&t2, NULL);
+#endif
+
+#ifdef IN_ORDER
+ // Push this thread to the top of the waiting stack
+ if (p->t_stack_top == -1 || p->t_stack_top > w->idx)
+ p->t_stack_top = w->idx;
+
+ p->t_stack[w->idx] = 1;
+ pthread_cond_wait(&w->pending_c, &p->pool_m);
+ p->t_stack[w->idx] = 0;
+
+ /* Find new t_stack_top */
+ {
+ int i;
+ p->t_stack_top = -1;
+ for (i = 0; i < p->tsize; i++) {
+ if (p->t_stack[i]) {
+ p->t_stack_top = i;
+ break;
+ }
+ }
+ }
+#else
+ pthread_cond_wait(&p->pending_c, &p->pool_m);
+#endif
+
+#ifdef DEBUG_TIME
+ gettimeofday(&t3, NULL);
+ p->wait_time += TDIFF(t3,t2);
+ w->wait_time += TDIFF(t3,t2);
+#endif
+ p->nwaiting--;
+ }
+
+ if (p->shutdown) {
+#ifdef DEBUG_TIME
+ p->total_time += TDIFF(t3,t1);
+#endif
+#ifdef DEBUG
+ fprintf(stderr, "%d: Shutting down\n", worker_id(p));
+#endif
+ pthread_mutex_unlock(&p->pool_m);
+ pthread_exit(NULL);
+ }
+
+ j = p->head;
+ if (!(p->head = j->next))
+ p->tail = NULL;
+
+ if (p->njobs-- >= p->qsize)
+ pthread_cond_signal(&p->full_c);
+
+ if (p->njobs == 0)
+ pthread_cond_signal(&p->empty_c);
+
+ pthread_mutex_unlock(&p->pool_m);
+
+ // We have job 'j' - now execute it.
+ t_pool_add_result(j, j->func(j->arg));
+#ifdef DEBUG_TIME
+ pthread_mutex_lock(&p->pool_m);
+ gettimeofday(&t3, NULL);
+ p->total_time += TDIFF(t3,t1);
+ pthread_mutex_unlock(&p->pool_m);
+#endif
+ memset(j, 0xbb, sizeof(*j));
+ free(j);
+ }
+
+ return NULL;
+}
+
+/*
+ * Creates a worker pool of length qsize with tsize worker threads.
+ *
+ * Returns pool pointer on success;
+ * NULL on failure
+ */
+t_pool *t_pool_init(int qsize, int tsize) {
+ int i;
+ t_pool *p = malloc(sizeof(*p));
+ p->qsize = qsize;
+ p->tsize = tsize;
+ p->njobs = 0;
+ p->nwaiting = 0;
+ p->shutdown = 0;
+ p->head = p->tail = NULL;
+ p->t_stack = NULL;
+#ifdef DEBUG_TIME
+ p->total_time = p->wait_time = 0;
+#endif
+
+ p->t = malloc(tsize * sizeof(p->t[0]));
+
+ pthread_mutex_init(&p->pool_m, NULL);
+ pthread_cond_init(&p->empty_c, NULL);
+ pthread_cond_init(&p->full_c, NULL);
+
+ pthread_mutex_lock(&p->pool_m);
+
+#ifdef IN_ORDER
+ if (!(p->t_stack = malloc(tsize * sizeof(*p->t_stack))))
+ return NULL;
+ p->t_stack_top = -1;
+
+ for (i = 0; i < tsize; i++) {
+ t_pool_worker_t *w = &p->t[i];
+ p->t_stack[i] = 0;
+ w->p = p;
+ w->idx = i;
+ w->wait_time = 0;
+ pthread_cond_init(&w->pending_c, NULL);
+ if (0 != pthread_create(&w->tid, NULL, t_pool_worker, w))
+ return NULL;
+ }
+#else
+ pthread_cond_init(&p->pending_c, NULL);
+
+ for (i = 0; i < tsize; i++) {
+ t_pool_worker_t *w = &p->t[i];
+ w->p = p;
+ w->idx = i;
+ pthread_cond_init(&w->pending_c, NULL);
+ if (0 != pthread_create(&w->tid, NULL, t_pool_worker, w))
+ return NULL;
+ }
+#endif
+
+ pthread_mutex_unlock(&p->pool_m);
+
+ return p;
+}
+
+/*
+ * Adds an item to the work pool.
+ *
+ * FIXME: Maybe return 1,0,-1 and distinguish between job dispathed vs
+ * result returned. Ie rather than blocking on full queue we're permitted
+ * to return early on "result available" event too.
+ * Caller would then have a while loop around t_pool_dispatch.
+ * Or, return -1 and set errno to EAGAIN to indicate job not yet submitted.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int t_pool_dispatch(t_pool *p, t_results_queue *q,
+ void *(*func)(void *arg), void *arg) {
+ return t_pool_dispatch2(p, q, func, arg, 0);
+}
+
+/*
+ * As above but optional non-block flag.
+ *
+ * nonblock 0 => block if input queue is full
+ * nonblock +1 => don't block if input queue is full, but do not add task
+ * nonblock -1 => add task regardless of whether queue is full (over-size)
+ */
+int t_pool_dispatch2(t_pool *p, t_results_queue *q,
+ void *(*func)(void *arg), void *arg, int nonblock) {
+ t_pool_job *j;
+
+#ifdef DEBUG
+ fprintf(stderr, "Dispatching job for queue %p, serial %d\n", q, q->curr_serial);
+#endif
+
+ pthread_mutex_lock(&p->pool_m);
+
+ if (p->njobs >= p->qsize && nonblock == 1) {
+ pthread_mutex_unlock(&p->pool_m);
+ errno = EAGAIN;
+ return -1;
+ }
+
+ if (!(j = malloc(sizeof(*j))))
+ return -1;
+ j->func = func;
+ j->arg = arg;
+ j->next = NULL;
+ j->p = p;
+ j->q = q;
+ if (q) {
+ pthread_mutex_lock(&q->result_m);
+ j->serial = q->curr_serial++;
+ q->pending++;
+ pthread_mutex_unlock(&q->result_m);
+ } else {
+ j->serial = 0;
+ }
+
+ // Check if queue is full
+ if (nonblock == 0)
+ while (p->njobs >= p->qsize)
+ pthread_cond_wait(&p->full_c, &p->pool_m);
+
+ p->njobs++;
+
+// if (q->curr_serial % 100 == 0)
+// fprintf(stderr, "p->njobs = %d p->qsize = %d\n", p->njobs, p->qsize);
+
+ if (p->tail) {
+ p->tail->next = j;
+ p->tail = j;
+ } else {
+ p->head = p->tail = j;
+ }
+
+#ifdef DEBUG
+ fprintf(stderr, "Dispatched (serial %d)\n", j->serial);
+#endif
+
+ // Let a worker know we have data.
+#ifdef IN_ORDER
+ // Keep incoming queue at 1 per running thread, so there is always
+ // something waiting when they end their current task. If we go above
+ // this signal to start more threads (if available). This has the effect
+ // of concentrating jobs to fewer cores when we are I/O bound, which in
+ // turn benefits systems with auto CPU frequency scaling.
+ if (p->t_stack_top >= 0 && p->njobs > p->tsize - p->nwaiting)
+ pthread_cond_signal(&p->t[p->t_stack_top].pending_c);
+#else
+ pthread_cond_signal(&p->pending_c);
+#endif
+
+ pthread_mutex_unlock(&p->pool_m);
+
+ return 0;
+}
+
+/*
+ * Flushes the pool, but doesn't exit. This simply drains the queue and
+ * ensures all worker threads have finished their current task.
+ *
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int t_pool_flush(t_pool *p) {
+ int i;
+
+#ifdef DEBUG
+ fprintf(stderr, "Flushing pool %p\n", p);
+#endif
+
+ // Drains the queue
+ pthread_mutex_lock(&p->pool_m);
+
+ // Wake up everything for the final sprint!
+ for (i = 0; i < p->tsize; i++)
+ if (p->t_stack[i])
+ pthread_cond_signal(&p->t[i].pending_c);
+
+ while (p->njobs || p->nwaiting != p->tsize)
+ pthread_cond_wait(&p->empty_c, &p->pool_m);
+
+ pthread_mutex_unlock(&p->pool_m);
+
+#ifdef DEBUG
+ fprintf(stderr, "Flushed complete for pool %p, njobs=%d, nwaiting=%d\n",
+ p, p->njobs, p->nwaiting);
+#endif
+
+ return 0;
+}
+
+/*
+ * Destroys a thread pool. If 'kill' is true the threads are terminated now,
+ * otherwise they are joined into the main thread so they will finish their
+ * current work load.
+ *
+ * Use t_pool_destroy(p,0) after a t_pool_flush(p) on a normal shutdown or
+ * t_pool_destroy(p,1) to quickly exit after a fatal error.
+ */
+void t_pool_destroy(t_pool *p, int kill) {
+ int i;
+
+#ifdef DEBUG
+ fprintf(stderr, "Destroying pool %p, kill=%d\n", p, kill);
+#endif
+
+ /* Send shutdown message to worker threads */
+ if (!kill) {
+ pthread_mutex_lock(&p->pool_m);
+ p->shutdown = 1;
+
+#ifdef DEBUG
+ fprintf(stderr, "Sending shutdown request\n");
+#endif
+
+#ifdef IN_ORDER
+ for (i = 0; i < p->tsize; i++)
+ pthread_cond_signal(&p->t[i].pending_c);
+#else
+ pthread_cond_broadcast(&p->pending_c);
+#endif
+ pthread_mutex_unlock(&p->pool_m);
+
+#ifdef DEBUG
+ fprintf(stderr, "Shutdown complete\n");
+#endif
+ for (i = 0; i < p->tsize; i++)
+ pthread_join(p->t[i].tid, NULL);
+ } else {
+ for (i = 0; i < p->tsize; i++)
+ pthread_kill(p->t[i].tid, SIGINT);
+ }
+
+ pthread_mutex_destroy(&p->pool_m);
+ pthread_cond_destroy(&p->empty_c);
+ pthread_cond_destroy(&p->full_c);
+#ifdef IN_ORDER
+ for (i = 0; i < p->tsize; i++)
+ pthread_cond_destroy(&p->t[i].pending_c);
+#else
+ pthread_cond_destroy(&p->pending_c);
+#endif
+
+#ifdef DEBUG_TIME
+ fprintf(stderr, "Total time=%f\n", p->total_time / 1000000.0);
+ fprintf(stderr, "Wait time=%f\n", p->wait_time / 1000000.0);
+ fprintf(stderr, "%d%% utilisation\n",
+ (int)(100 - ((100.0 * p->wait_time) / p->total_time + 0.5)));
+ for (i = 0; i < p->tsize; i++)
+ fprintf(stderr, "%d: Wait time=%f\n", i,
+ p->t[i].wait_time / 1000000.0);
+#endif
+
+ if (p->t_stack)
+ free(p->t_stack);
+
+ free(p->t);
+ free(p);
+
+#ifdef DEBUG
+ fprintf(stderr, "Destroyed pool %p\n", p);
+#endif
+}
+
+
+/*-----------------------------------------------------------------------------
+ * Test app.
+ */
+
+#ifdef TEST_MAIN
+
+#include <stdio.h>
+#include <math.h>
+
+void *doit(void *arg) {
+ int i, k, x = 0;
+ int job = *(int *)arg;
+ int *res;
+
+ printf("Worker: execute job %d\n", job);
+
+ usleep(random() % 1000000); // to coerce job completion out of order
+ if (0) {
+ for (k = 0; k < 100; k++) {
+ for (i = 0; i < 100000; i++) {
+ x++;
+ x += x * sin(i);
+ x += x * cos(x);
+ }
+ }
+ x *= 100;
+ x += job;
+ } else {
+ x = job*job;
+ }
+
+ printf("Worker: job %d terminating, x=%d\n", job, x);
+
+ free(arg);
+
+ res = malloc(sizeof(*res));
+ *res = x;
+
+ return res;
+}
+
+#define NTHREADS 8
+
+int main(int argc, char **argv) {
+ t_pool *p = t_pool_init(NTHREADS*2, NTHREADS);
+ t_results_queue *q = t_results_queue_init();
+ int i;
+ t_pool_result *r;
+
+ // Dispatch jobs
+ for (i = 0; i < 20; i++) {
+ int *ip = malloc(sizeof(*ip));
+ *ip = i;
+ printf("Submitting %d\n", i);
+ t_pool_dispatch(p, q, doit, ip);
+
+ // Check for results
+ if ((r = t_pool_next_result(q))) {
+ printf("RESULT: %d\n", *(int *)r->data);
+ t_pool_delete_result(r, 1);
+ }
+ }
+
+ t_pool_flush(p);
+
+ while ((r = t_pool_next_result(q))) {
+ printf("RESULT: %d\n", *(int *)r->data);
+ t_pool_delete_result(r, 1);
+ }
+
+ t_pool_destroy(p, 0);
+ t_results_queue_destroy(q);
+
+ return 0;
+}
+#endif
--- /dev/null
+/*
+Copyright (c) 2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+/*
+ * This file implements a thread pool for multi-threading applications.
+ * It consists of two distinct interfaces: thread pools an results queues.
+ *
+ * The pool of threads is given a function pointer and void* data to pass in.
+ * This means the pool can run jobs of multiple types, albeit first come
+ * first served with no job scheduling.
+ *
+ * Upon completion, the return value from the function pointer is added to
+ * a results queue. We may have multiple queues in use for the one pool.
+ *
+ * An example: reading from BAM and writing to CRAM with 10 threads. We'll
+ * have a pool of 10 threads and two results queues holding decoded BAM blocks
+ * and encoded CRAM blocks respectively.
+ */
+
+#ifndef _THREAD_POOL_H_
+#define _THREAD_POOL_H_
+
+#include <pthread.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+struct t_pool;
+struct t_results_queue;
+
+typedef struct t_pool_job {
+ void *(*func)(void *arg);
+ void *arg;
+ struct t_pool_job *next;
+
+ struct t_pool *p;
+ struct t_results_queue *q;
+ int serial;
+} t_pool_job;
+
+typedef struct t_res {
+ struct t_res *next;
+ int serial; // sequential number for ordering
+ void *data; // result itself
+} t_pool_result;
+
+struct t_pool;
+
+typedef struct {
+ struct t_pool *p;
+ int idx;
+ pthread_t tid;
+ pthread_cond_t pending_c;
+ long long wait_time;
+} t_pool_worker_t;
+
+typedef struct t_pool {
+ int qsize; // size of queue
+ int njobs; // pending job count
+ int nwaiting; // how many workers waiting for new jobs
+ int shutdown; // true if pool is being destroyed
+
+ // queue of pending jobs
+ t_pool_job *head, *tail;
+
+ // threads
+ int tsize; // maximum number of jobs
+ t_pool_worker_t *t;
+
+ // Mutexes
+ pthread_mutex_t pool_m; // used when updating head/tail
+
+ pthread_cond_t empty_c;
+ pthread_cond_t pending_c; // not empty
+ pthread_cond_t full_c;
+
+ // array of worker IDs free
+ int *t_stack, t_stack_top;
+
+ // Debugging to check wait time
+ long long total_time, wait_time;
+} t_pool;
+
+typedef struct t_results_queue {
+ t_pool_result *result_head;
+ t_pool_result *result_tail;
+ int next_serial;
+ int curr_serial;
+ int queue_len; // number of items in queue
+ int pending; // number of pending items (in progress or in pool list)
+ pthread_mutex_t result_m;
+ pthread_cond_t result_avail_c;
+} t_results_queue;
+
+
+/*
+ * Creates a worker pool of length qsize with tsize worker threads.
+ *
+ * Returns pool pointer on success;
+ * NULL on failure
+ */
+t_pool *t_pool_init(int qsize, int tsize);
+
+/*
+ * Adds an item to the work pool.
+ *
+ * FIXME: Maybe return 1,0,-1 and distinguish between job dispathed vs
+ * result returned. Ie rather than blocking on full queue we're permitted
+ * to return early on "result available" event too.
+ * Caller would then have a while loop around t_pool_dispatch.
+ * Or, return -1 and set errno to E_AGAIN to indicate job not yet submitted.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int t_pool_dispatch(t_pool *p, t_results_queue *q,
+ void *(*func)(void *arg), void *arg);
+int t_pool_dispatch2(t_pool *p, t_results_queue *q,
+ void *(*func)(void *arg), void *arg, int nonblock);
+
+/*
+ * Flushes the pool, but doesn't exit. This simply drains the queue and
+ * ensures all worker threads have finished their current task.
+ *
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int t_pool_flush(t_pool *p);
+
+/*
+ * Destroys a thread pool. If 'kill' is true the threads are terminated now,
+ * otherwise they are joined into the main thread so they will finish their
+ * current work load.
+ *
+ * Use t_pool_destroy(p,0) after a t_pool_flush(p) on a normal shutdown or
+ * t_pool_destroy(p,1) to quickly exit after a fatal error.
+ */
+void t_pool_destroy(t_pool *p, int kill);
+
+/*
+ * Pulls a result off the head of the result queue. Caller should
+ * free it (and any internals as appropriate) after use. This doesn't
+ * wait for a result to be present.
+ *
+ * Results will be returned in strict order.
+ *
+ * Returns t_pool_result pointer if a result is ready.
+ * NULL if not.
+ */
+t_pool_result *t_pool_next_result(t_results_queue *q);
+t_pool_result *t_pool_next_result_wait(t_results_queue *q);
+
+/*
+ * Frees a result 'r' and if free_data is true also frees
+ * the internal r->data result too.
+ */
+void t_pool_delete_result(t_pool_result *r, int free_data);
+
+/*
+ * Initialises a results queue.
+ *
+ * Results queue pointer on success;
+ * NULL on failure
+ */
+t_results_queue *t_results_queue_init(void);
+
+/* Deallocates memory for a results queue */
+void t_results_queue_destroy(t_results_queue *q);
+
+/*
+ * Returns true if there are no items on the finished results queue and
+ * also none still pending.
+ */
+int t_pool_results_queue_empty(t_results_queue *q);
+
+/*
+ * Returns the number of completed jobs on the results queue.
+ */
+int t_pool_results_queue_len(t_results_queue *q);
+
+/*
+ * Returns the number of completed jobs plus the number queued up to run.
+ */
+int t_pool_results_queue_sz(t_results_queue *q);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _THREAD_POOL_H_ */
--- /dev/null
+/*
+Author: James Bonfield (jkb@sanger.ac.uk)
+
+Copyright (c) 1995-1996 MEDICAL RESEARCH COUNCIL
+All rights reserved
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1 Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2 Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3 Neither the name of the MEDICAL RESEARCH COUNCIL, THE LABORATORY OF
+MOLECULAR BIOLOGY nor the names of its contributors may be used to endorse or
+promote products derived from this software without specific prior written
+permission.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR
+ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
+(INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
+LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON
+ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+(INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
+SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+ */
+
+/*
+Copyright (c) 2004, 2009, 2011-2012 Genome Research Ltd.
+
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <stdio.h>
+#include <stdlib.h>
+#include <stdarg.h>
+#include <sys/types.h>
+#include <string.h>
+
+#include "cram/vlen.h"
+#include "cram/os.h"
+
+#ifndef MAX
+#define MAX(a,b) ((a)>(b)?(a):(b))
+#endif
+
+#ifndef ABS
+#define ABS(a) ((a)>0?(a):-(a))
+#endif
+
+/* #define DEBUG_printf(a,n) printf(a,n) */
+#define DEBUG_printf(a,n)
+
+/*
+ * vlen: 27/10/95 written by James Bonfield, jkb@mrc-lmb.cam.ac.uk
+ *
+ * Given sprintf style of arguments this routine returns the maximum
+ * size of buffer needed to allocate to use with sprintf. It errs on
+ * the side of caution by being simplistic in its approach: we assume
+ * all numbers are of maximum length.
+ *
+ * Handles the usual type conversions (%[%diuaxXcfeEgGpns]), but not
+ * the 'wide' character conversions (%C and %S).
+ * Precision is handled in the correct formats, including %*.*
+ * notations.
+ * Additionally, some of the more dubious (but probably illegal) cases
+ * are supported (eg "%10%" will expand to " %" on many
+ * systems).
+ *
+ * We also assume that the largest integer and larger pointer are 64
+ * bits, which at least covers the machines we'll need it for.
+ */
+int flen(char *fmt, ...)
+{
+ va_list args;
+
+ va_start(args, fmt);
+ return vflen(fmt, args);
+}
+
+int vflen(char *fmt, va_list ap)
+{
+ int len = 0;
+ char *cp, c;
+ long long l;
+ int i;
+ double d;
+
+ /*
+ * This code modifies 'ap', but we do not know if va_list is a structure
+ * or a pointer to an array so we do not know if it is a local variable
+ * or not.
+ * C99 gets around this by defining va_copy() to make copies of ap, but
+ * this does not exist on all systems.
+ * For now, I just assume that when va_list is a pointer the system also
+ * provides a va_copy macro to work around this problem. The only system
+ * I have seen needing this so far was Linux on AMD64.
+ */
+#if defined(HAVE_VA_COPY)
+ va_list ap_local;
+ va_copy(ap_local, ap);
+# define ap ap_local
+#endif
+
+ for(cp = fmt; *cp; cp++) {
+ switch(*cp) {
+
+ /* A format specifier */
+ case '%': {
+ char *endp;
+ long conv_len1=0, conv_len2=0, conv_len=0;
+ signed int arg_size;
+
+ /* Firstly, strip the modifier flags (+-#0 and [space]) */
+ for(; (c=*++cp);) {
+ if ('#' == c)
+ len+=2; /* Worst case of "0x" */
+ else if ('-' == c || '+' == c || ' ' == c)
+ len++;
+ else
+ break;
+ }
+
+ /* Width specifier */
+ l = strtol(cp, &endp, 10);
+ if (endp != cp) {
+ cp = endp;
+ conv_len = conv_len1 = l;
+ } else if (*cp == '*') {
+ conv_len = conv_len1 = (int)va_arg(ap, int);
+ cp++;
+ }
+
+ /* Precision specifier */
+ if ('.' == *cp) {
+ cp++;
+ conv_len2 = strtol(cp, &endp, 10);
+ if (endp != cp) {
+ cp = endp;
+ } else if (*cp == '*') {
+ conv_len2 = (int)va_arg(ap, int);
+ cp++;
+ }
+ conv_len = MAX(conv_len1, conv_len2);
+ }
+
+ /* Short/long identifier */
+ if ('h' == *cp) {
+ arg_size = -1; /* short */
+ cp++;
+ } else if ('l' == *cp) {
+ arg_size = 1; /* long */
+ cp++;
+ if ('l' == *cp) {
+ arg_size = 2; /* long long */
+ cp++;
+ }
+ } else {
+ arg_size = 0; /* int */
+ }
+
+ /* The actual type */
+ switch (*cp) {
+ case '%':
+ /*
+ * Not real ANSI I suspect, but we'll allow for the
+ * completely daft "%10%" example.
+ */
+ len += MAX(conv_len1, 1);
+ break;
+
+ case 'd':
+ case 'i':
+ case 'u':
+ case 'a':
+ case 'x':
+ case 'X':
+ /* Remember: char and short are sent as int on the stack */
+ if (arg_size == -1)
+ l = (long)va_arg(ap, int);
+ else if (arg_size == 1)
+ l = va_arg(ap, long);
+ else if (arg_size == 2)
+ l = va_arg(ap, long long);
+ else
+ l = (long)va_arg(ap, int);
+
+ DEBUG_printf("%d", l);
+
+ /*
+ * No number can be more than 24 characters so we'll take
+ * the max of conv_len and 24 (23 is len(2^64) in octal).
+ * All that work above and we then go and estimate ;-),
+ * but it's needed incase someone does %500d.
+ */
+ len += MAX(conv_len, 23);
+ break;
+
+ case 'c':
+ i = va_arg(ap, int);
+ DEBUG_printf("%c", i);
+ /*
+ * Note that %10c and %.10c act differently.
+ * Besides, I think precision is not really allowed for %c.
+ */
+ len += MAX(conv_len1, i>=0x80 ?MB_CUR_MAX :1);
+ break;
+
+ case 'f':
+ d = va_arg(ap, double);
+ DEBUG_printf("%f", d);
+ /*
+ * Maybe "Inf" or "NaN", but we'll not worry about that.
+ * Again, err on side of caution and take max of conv_len
+ * and max length of a double. The worst case I can
+ * think of is 317 characters (-1[308 zeros].000000)
+ * without using precision codes. That's horrid. I
+ * cheat and either use 317 or 15 depending on how
+ * large the number is as I reckon 99% of floats
+ * aren't that long.
+ */
+ l = (ABS(d) > 1000000) ? 317 : 15;
+ l = MAX(l, conv_len1 + 2);
+ if (conv_len2) l += conv_len2 - 6;
+ len += l;
+ break;
+
+ case 'e':
+ case 'E':
+ case 'g':
+ case 'G':
+ d = va_arg(ap, double);
+ DEBUG_printf("%g", d);
+ /*
+ * Maybe "Inf" or "NaN", but we'll not worry about that
+ * Again, err on side of caution and take max of conv_len
+ * and max length of a double (which defaults to only
+ * '-' + 6 + '.' + 'E[+-]xxx' == 13.
+ */
+ len += MAX(conv_len, 13);
+ break;
+
+ case 'p':
+ l = (long)va_arg(ap, void *);
+ /*
+ * Max pointer is 64bits == 16 chars (on alpha),
+ * == 20 with + "0x".
+ */
+ DEBUG_printf("%p", (void *)l);
+ len += MAX(conv_len, 20);
+ break;
+
+ case 'n':
+ /* produces no output */
+ break;
+
+ case 's': {
+ char *s = (char *)va_arg(ap, char *);
+ DEBUG_printf("%s", s);
+
+ if (!conv_len2) {
+ len += MAX(conv_len, (int)strlen(s));
+ } else {
+ len += conv_len;
+ }
+ break;
+ }
+
+ default:
+ /* wchar_t types of 'C' and 'S' aren't supported */
+ DEBUG_printf("Arg is %c\n", *cp);
+ }
+
+ }
+
+ case '\0':
+ break;
+
+ default:
+ DEBUG_printf("%c", *cp);
+ len++;
+ }
+ }
+
+ va_end(ap);
+
+ return len+1; /* one for the null character */
+}
+
+#if 0
+int main() {
+ int l;
+ char buf[10000];
+
+ sprintf(buf, "d: %d\n", 500);
+ l = flen("d: %d\n", 500);
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "");
+ l = flen("");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%s\n","test");
+ l = flen("%s\n", "test");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%c\n", 'a');
+ l = flen("%c\n", 'a');
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%31.30f\n", -9999.99);
+ l = flen("%31.30f\n", -9999.99);
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%f\n", -1e308);
+ l = flen("%f\n", -1e308);
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%.9f\n", -1e308);
+ l = flen("%.9f\n", -1e308);
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%10.20f\n", -1.999222333);
+ l = flen("%10.20f\n", -1.999222333);
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%#g\n", -3.14159265358e-222);
+ l = flen("%#g\n", -3.1415927e-222);
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%e\n", -123456789123456789.1);
+ l = flen("%e\n", -123456789123456789.1);
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%c %f %d %s %c %g %ld %s\n", 'a', 3.1, 9, "one", 'b', 4.2, 9, "two");
+ l = flen("%c %f %d %s %c %g %ld %s\n", 'a', 3.1, 9, "one", 'b', 4.2, 9, "two");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%*.*e %*c\n", 10, 5, 9.0, 20, 'x');
+ l = flen("%*.*e %*c\n", 10, 5, 9.0, 20, 'x');
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%10c\n", 'z');
+ l = flen("%10c\n", 'z');
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%.10c\n", 'z');
+ l = flen("%.10c\n", 'z');
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%10d\n", 'z');
+ l = flen("%10d\n", 'z');
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%.10d\n", 'z');
+ l = flen("%.10d\n", 'z');
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%10%\n");
+ l = flen("%10%\n");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%.10%\n");
+ l = flen("%.10%\n");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%s\n", "0123456789");
+ l = flen("%s\n", "0123456789");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%5s\n", "0123456789");
+ l = flen("%5s\n", "0123456789");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%50s\n", "0123456789");
+ l = flen("%50s\n", "0123456789");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%.5s\n", "0123456789");
+ l = flen("%.5s\n", "0123456789");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%.50s\n", "0123456789");
+ l = flen("%.50s\n", "0123456789");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%5.50s\n", "0123456789");
+ l = flen("%5.50s\n", "0123456789");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ sprintf(buf, "%50.5s\n", "0123456789");
+ l = flen("%50.5s\n", "0123456789");
+ printf("%d %d\n\n", strlen(buf), l);
+
+ return 0;
+}
+#endif
--- /dev/null
+/*
+Author: James Bonfield (jkb@sanger.ac.uk)
+
+Copyright (c) 1995-1996 MEDICAL RESEARCH COUNCIL
+All rights reserved
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1 Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2 Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3 Neither the name of the MEDICAL RESEARCH COUNCIL, THE LABORATORY OF
+MOLECULAR BIOLOGY nor the names of its contributors may be used to endorse or
+promote products derived from this software without specific prior written
+permission.
+
+THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR
+ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
+(INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
+LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON
+ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
+(INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
+SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _VLEN_H_
+#define _VLEN_H_
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+extern int vflen(char *fmt, va_list ap);
+extern int flen(char *fmt, ...);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _VLEN_H_ */
--- /dev/null
+/*
+Copyright (c) 2009-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#include <config.h>
+
+#include <stdlib.h>
+#include <unistd.h>
+
+#include "cram/os.h"
+#include "cram/zfio.h"
+
+/* ------------------------------------------------------------------------ */
+/* Some wrappers around FILE * vs gzFile *, allowing for either */
+
+/*
+ * gzopen() works on both compressed and uncompressed data, but it has
+ * a significant performance hit even for uncompressed data (tested as
+ * 25s using FILE* to 46s via gzOpen and 66s via gzOpen when gzipped).
+ *
+ * Hence we use our own wrapper 'zfp' which is a FILE* when uncompressed
+ * and gzFile* when compressed. This also means we could hide bzopen in
+ * there too if desired.
+ */
+
+off_t zftello(zfp *zf) {
+ return zf->fp ? ftello(zf->fp) : -1;
+}
+
+int zfseeko(zfp *zf, off_t offset, int whence) {
+ return zf->fp ? fseeko(zf->fp, offset, whence) : -1;
+}
+
+
+/*
+ * A wrapper for either fgets or gzgets depending on what has been
+ * opened.
+ */
+char *zfgets(char *line, int size, zfp *zf) {
+ if (zf->fp)
+ return fgets(line, size, zf->fp);
+ else
+ return gzgets(zf->gz, line, size);
+}
+
+/*
+ * A wrapper for either fputs or gzputs depending on what has been
+ * opened.
+ */
+int zfputs(char *line, zfp *zf) {
+ if (zf->fp)
+ return fputs(line, zf->fp);
+ else
+ return gzputs(zf->gz, line) ? 0 : EOF;
+}
+
+/*
+ * Peeks at and returns the next character without consuming it from the
+ * input. (Ie a combination of getc and ungetc).
+ */
+int zfpeek(zfp *zf) {
+ int c;
+
+ if (zf->fp) {
+ c = getc(zf->fp);
+ if (c != EOF)
+ ungetc(c, zf->fp);
+ } else {
+ c = gzgetc(zf->gz);
+ if (c != EOF)
+ gzungetc(c, zf->gz);
+ }
+
+ return c;
+}
+
+/* A replacement for either feof of gzeof */
+int zfeof(zfp *zf) {
+ return zf->fp ? feof(zf->fp) : gzeof(zf->gz);
+}
+
+/* A replacement for either fopen or gzopen */
+zfp *zfopen(const char *path, const char *mode) {
+ char path2[1024];
+ zfp *zf;
+
+ if (!(zf = (zfp *)malloc(sizeof(*zf))))
+ return NULL;
+ zf->fp = NULL;
+ zf->gz = NULL;
+
+ /* Try normal fopen */
+ if (mode[0] != 'z' && mode[1] != 'z' &&
+ NULL != (zf->fp = fopen(path, mode))) {
+ unsigned char magic[2];
+ if (2 != fread(magic, 1, 2, zf->fp)) {
+ free(zf);
+ return NULL;
+ }
+ if (!(magic[0] == 0x1f &&
+ magic[1] == 0x8b)) {
+ fseeko(zf->fp, 0, SEEK_SET);
+ return zf;
+ }
+
+ fclose(zf->fp);
+ zf->fp = NULL;
+ }
+
+#ifdef HAVE_POPEN
+ /*
+ * I've no idea why, by gzgets is VERY slow, maybe because it handles
+ * arbitrary seeks.
+ * popen to gzip -cd is 3 times faster though.
+ */
+ if (*mode == 'w') {
+ } else {
+ if (access(path, R_OK) == 0) {
+ sprintf(path2, "gzip -cd < %.*s", 1000, path);
+ if (NULL != (zf->fp = popen(path2, "r")))
+ return zf;
+ }
+
+ sprintf(path2, "gzip -cd < %.*s.gz", 1000, path);
+ if (NULL != (zf->fp = popen(path2, "r")))
+ return zf;
+
+ printf("Failed on %s\n", path);
+ } else {
+ sprintf(path2, "gzip > %.*s", 1000, path);
+ if (NULL != (zf->fp = popen(path2, "w")))
+ return zf;
+ }
+
+ printf("Failed on %s\n", path);
+ }
+#else
+ /* Gzopen instead */
+ if ((zf->gz = gzopen(path, mode)))
+ return zf;
+
+ sprintf(path2, "%.*s.gz", 1020, path);
+ if ((zf->gz = gzopen(path2, mode)))
+ return zf;
+#endif
+
+ perror(path);
+
+ free(zf);
+ return NULL;
+}
+
+int zfclose(zfp *zf) {
+ int r = (zf->fp) ? fclose(zf->fp) : gzclose(zf->gz);
+ free(zf);
+ return r;
+}
--- /dev/null
+/*
+Copyright (c) 2009-2013 Genome Research Ltd.
+Author: James Bonfield <jkb@sanger.ac.uk>
+
+Redistribution and use in source and binary forms, with or without
+modification, are permitted provided that the following conditions are met:
+
+ 1. Redistributions of source code must retain the above copyright notice,
+this list of conditions and the following disclaimer.
+
+ 2. Redistributions in binary form must reproduce the above copyright notice,
+this list of conditions and the following disclaimer in the documentation
+and/or other materials provided with the distribution.
+
+ 3. Neither the names Genome Research Ltd and Wellcome Trust Sanger
+Institute nor the names of its contributors may be used to endorse or promote
+products derived from this software without specific prior written permission.
+
+THIS SOFTWARE IS PROVIDED BY GENOME RESEARCH LTD AND CONTRIBUTORS "AS IS" AND
+ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
+WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
+DISCLAIMED. IN NO EVENT SHALL GENOME RESEARCH LTD OR CONTRIBUTORS BE LIABLE
+FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
+DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR
+SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
+CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY,
+OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE
+OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
+*/
+
+#ifndef _ZFIO_H_
+#define _ZFIO_H_
+
+#include <stdio.h>
+#include <zlib.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*
+ * Either a gzFile or a FILE.
+ */
+typedef struct {
+ FILE *fp;
+ gzFile gz;
+} zfp;
+
+off_t zftello(zfp *zf);
+int zfseeko(zfp *zf, off_t offset, int whence);
+char *zfgets(char *line, int size, zfp *zf);
+int zfputs(char *line, zfp *zf);
+zfp *zfopen(const char *path, const char *mode);
+int zfclose(zfp *zf);
+int zfpeek(zfp *zf);
+int zfeof(zfp *zf);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif /* _ZFIO_H_ */
--- /dev/null
+'\" t
+.TH faidx 5 "August 2015" "htslib" "Bioinformatics formats"
+.SH NAME
+faidx \- an index enabling random access to FASTA files
+.\"
+.\" Copyright (C) 2013, 2015 Genome Research Ltd.
+.\"
+.\" Author: John Marshall <jm18@sanger.ac.uk>
+.\"
+.\" Permission is hereby granted, free of charge, to any person obtaining a
+.\" copy of this software and associated documentation files (the "Software"),
+.\" to deal in the Software without restriction, including without limitation
+.\" the rights to use, copy, modify, merge, publish, distribute, sublicense,
+.\" and/or sell copies of the Software, and to permit persons to whom the
+.\" Software is furnished to do so, subject to the following conditions:
+.\"
+.\" The above copyright notice and this permission notice shall be included in
+.\" all copies or substantial portions of the Software.
+.\"
+.\" THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+.\" IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+.\" FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+.\" THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+.\" LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+.\" FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+.\" DEALINGS IN THE SOFTWARE.
+.\"
+.SH SYNOPSIS
+.IR file.fa .fai,
+.IR file.fasta .fai
+.SH DESCRIPTION
+Using an \fBfai index\fP file in conjunction with a FASTA file containing
+reference sequences enables efficient access to arbitrary regions within
+those reference sequences.
+The index file typically has the same filename as the corresponding FASTA
+file, with \fB.fai\fP appended.
+.P
+An \fBfai index\fP file is a text file consisting of lines each with
+five TAB-delimited columns:
+.TS
+lbl.
+NAME Name of this reference sequence
+LENGTH Total length of this reference sequence, in bases
+OFFSET Offset within the FASTA file of this sequence's first base
+LINEBASES The number of bases on each line
+LINEWIDTH The number of bytes in each line, including the newline
+.TE
+.P
+The \fBNAME\fP and \fBLENGTH\fP columns contain the same
+data as would appear in the \fBSN\fP and \fBLN\fP fields of a
+SAM \fB@SQ\fP header for the same reference sequence.
+.P
+The \fBOFFSET\fP column contains the offset within the FASTA file, in bytes
+starting from zero, of the first base of this reference sequence, i.e., of
+the character following the newline at the end of the "\fB>\fP" header line.
+Typically the lines of a \fBfai index\fP file appear in the order in which the
+reference sequences appear in the FASTA file, so \fB.fai\fP files are typically
+sorted according to this column.
+.P
+The \fBLINEBASES\fP column contains the number of bases in each of the sequence
+lines that form the body of this reference sequence, apart from the final line
+which may be shorter.
+The \fBLINEWIDTH\fP column contains the number of \fIbytes\fP in each of
+the sequence lines (except perhaps the final line), thus differing from
+\fBLINEBASES\fP in that it also counts the bytes forming the line terminator.
+.SS FASTA Files
+In order to be indexed with \fBsamtools faidx\fP, a FASTA file must be a text
+file of the form
+.LP
+.RS
+.RI > name
+.RI [ description ...]
+.br
+ATGCATGCATGCATGCATGCATGCATGCAT
+.br
+GCATGCATGCATGCATGCATGCATGCATGC
+.br
+ATGCAT
+.br
+.RI > name
+.RI [ description ...]
+.br
+ATGCATGCATGCAT
+.br
+GCATGCATGCATGC
+.br
+[...]
+.RE
+.LP
+In particular, each reference sequence must be "well-formatted", i.e., all
+of its sequence lines must be the same length, apart from the final sequence
+line which may be shorter.
+(While this sequence line length must be the same within each sequence,
+it may vary between different reference sequences in the same FASTA file.)
+.P
+This also means that although the FASTA file may have Unix- or Windows-style
+or other line termination, the newline characters present must be consistent,
+at least within each reference sequence.
+.P
+The \fBsamtools\fP implementation uses the first word of the "\fB>\fP" header
+line text (i.e., up to the first whitespace character, having skipped any
+initial whitespace after the ">") as the \fBNAME\fP column.
+.SH EXAMPLE
+For example, given this FASTA file
+.LP
+.RS
+>one
+.br
+ATGCATGCATGCATGCATGCATGCATGCAT
+.br
+GCATGCATGCATGCATGCATGCATGCATGC
+.br
+ATGCAT
+.br
+>two another chromosome
+.br
+ATGCATGCATGCAT
+.br
+GCATGCATGCATGC
+.br
+.RE
+.LP
+formatted with Unix-style (LF) line termination, the corresponding fai index
+would be
+.RS
+.TS
+lnnnn.
+one 66 5 30 31
+two 28 98 14 15
+.TE
+.RE
+.LP
+If the FASTA file were formatted with Windows-style (CR-LF) line termination,
+the fai index would be
+.RS
+.TS
+lnnnn.
+one 66 6 30 32
+two 28 103 14 16
+.TE
+.RE
+.SH SEE ALSO
+.IR samtools (1)
+.TP
+http://en.wikipedia.org/wiki/FASTA_format
+Further description of the FASTA format
--- /dev/null
+/* faidx.c -- FASTA random access.
+
+ Copyright (C) 2008, 2009, 2013-2016 Genome Research Ltd.
+ Portions copyright (C) 2011 Broad Institute.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <ctype.h>
+#include <string.h>
+#include <stdlib.h>
+#include <stdio.h>
+#include <inttypes.h>
+#include <errno.h>
+
+#include "htslib/bgzf.h"
+#include "htslib/faidx.h"
+#include "htslib/hfile.h"
+#include "htslib/khash.h"
+#include "htslib/kstring.h"
+
+typedef struct {
+ int32_t line_len, line_blen;
+ int64_t len;
+ uint64_t offset;
+} faidx1_t;
+KHASH_MAP_INIT_STR(s, faidx1_t)
+
+struct __faidx_t {
+ BGZF *bgzf;
+ int n, m;
+ char **name;
+ khash_t(s) *hash;
+};
+
+#ifndef kroundup32
+#define kroundup32(x) (--(x), (x)|=(x)>>1, (x)|=(x)>>2, (x)|=(x)>>4, (x)|=(x)>>8, (x)|=(x)>>16, ++(x))
+#endif
+
+static inline int fai_insert_index(faidx_t *idx, const char *name, int len, int line_len, int line_blen, uint64_t offset)
+{
+ if (!name) {
+ fprintf(stderr, "[fai_build_core] malformed line\n");
+ return -1;
+ }
+
+ char *name_key = strdup(name);
+ int absent;
+ khint_t k = kh_put(s, idx->hash, name_key, &absent);
+ faidx1_t *v = &kh_value(idx->hash, k);
+
+ if (! absent) {
+ fprintf(stderr, "[fai_build_core] ignoring duplicate sequence \"%s\" at byte offset %"PRIu64"\n", name, offset);
+ free(name_key);
+ return 0;
+ }
+
+ if (idx->n == idx->m) {
+ char **tmp;
+ idx->m = idx->m? idx->m<<1 : 16;
+ if (!(tmp = (char**)realloc(idx->name, sizeof(char*) * idx->m))) {
+ fprintf(stderr, "[fai_build_core] out of memory\n");
+ return -1;
+ }
+ idx->name = tmp;
+ }
+ idx->name[idx->n++] = name_key;
+ v->len = len;
+ v->line_len = line_len;
+ v->line_blen = line_blen;
+ v->offset = offset;
+
+ return 0;
+}
+
+faidx_t *fai_build_core(BGZF *bgzf)
+{
+ kstring_t name = { 0, 0, NULL };
+ int c;
+ int line_len, line_blen, state;
+ int l1, l2;
+ faidx_t *idx;
+ uint64_t offset;
+ int64_t len;
+
+ idx = (faidx_t*)calloc(1, sizeof(faidx_t));
+ idx->hash = kh_init(s);
+ len = line_len = line_blen = -1; state = 0; l1 = l2 = -1; offset = 0;
+ while ( (c=bgzf_getc(bgzf))>=0 ) {
+ if (c == '\n') { // an empty line
+ if (state == 1) {
+ offset = bgzf_utell(bgzf);
+ continue;
+ } else if ((state == 0 && len < 0) || state == 2) continue;
+ else if (state == 0) { state = 2; continue; }
+ }
+ if (c == '>') { // fasta header
+ if (len >= 0) {
+ if (fai_insert_index(idx, name.s, len, line_len, line_blen, offset) != 0)
+ goto fail;
+ }
+
+ name.l = 0;
+ while ((c = bgzf_getc(bgzf)) >= 0)
+ if (! isspace(c)) kputc_(c, &name);
+ else if (name.l > 0 || c == '\n') break;
+ kputsn("", 0, &name);
+
+ if ( c<0 ) {
+ fprintf(stderr, "[fai_build_core] the last entry has no sequence\n");
+ goto fail;
+ }
+ if (c != '\n') while ( (c=bgzf_getc(bgzf))>=0 && c != '\n');
+ state = 1; len = 0;
+ offset = bgzf_utell(bgzf);
+ } else {
+ if (state == 3) {
+ fprintf(stderr, "[fai_build_core] inlined empty line is not allowed in sequence '%s'.\n", name.s);
+ goto fail;
+ }
+ if (state == 2) state = 3;
+ l1 = l2 = 0;
+ do {
+ ++l1;
+ if (isgraph(c)) ++l2;
+ } while ( (c=bgzf_getc(bgzf))>=0 && c != '\n');
+ if (state == 3 && l2) {
+ fprintf(stderr, "[fai_build_core] different line length in sequence '%s'.\n", name.s);
+ goto fail;
+ }
+ ++l1; len += l2;
+ if (state == 1) line_len = l1, line_blen = l2, state = 0;
+ else if (state == 0) {
+ if (l1 != line_len || l2 != line_blen) state = 2;
+ }
+ }
+ }
+
+ if (len >= 0) {
+ if (fai_insert_index(idx, name.s, len, line_len, line_blen, offset) != 0)
+ goto fail;
+ } else {
+ goto fail;
+ }
+
+ free(name.s);
+ return idx;
+
+fail:
+ free(name.s);
+ fai_destroy(idx);
+ return NULL;
+}
+
+void fai_save(const faidx_t *fai, FILE *fp)
+{
+ khint_t k;
+ int i;
+ for (i = 0; i < fai->n; ++i) {
+ faidx1_t x;
+ k = kh_get(s, fai->hash, fai->name[i]);
+ x = kh_value(fai->hash, k);
+#ifdef _WIN32
+ fprintf(fp, "%s\t%d\t%ld\t%d\t%d\n", fai->name[i], (int)x.len, (long)x.offset, (int)x.line_blen, (int)x.line_len);
+#else
+ fprintf(fp, "%s\t%d\t%lld\t%d\t%d\n", fai->name[i], (int)x.len, (long long)x.offset, (int)x.line_blen, (int)x.line_len);
+#endif
+ }
+}
+
+static faidx_t *fai_read(FILE *fp, const char *fname)
+{
+ faidx_t *fai;
+ char *buf, *p;
+ int len, line_len, line_blen;
+#ifdef _WIN32
+ long offset;
+#else
+ long long offset;
+#endif
+ fai = (faidx_t*)calloc(1, sizeof(faidx_t));
+ fai->hash = kh_init(s);
+ buf = (char*)calloc(0x10000, 1);
+ while (fgets(buf, 0x10000, fp)) {
+ for (p = buf; *p && isgraph(*p); ++p);
+ *p = 0; ++p;
+#ifdef _WIN32
+ sscanf(p, "%d%ld%d%d", &len, &offset, &line_blen, &line_len);
+#else
+ sscanf(p, "%d%lld%d%d", &len, &offset, &line_blen, &line_len);
+#endif
+ if (fai_insert_index(fai, buf, len, line_len, line_blen, offset) != 0) {
+ free(buf);
+ return NULL;
+ }
+ }
+ free(buf);
+ if (ferror(fp)) {
+ fprintf(stderr, "[fai_load] error while reading \"%s\": %s\n", fname, strerror(errno));
+ fai_destroy(fai);
+ return NULL;
+ }
+ return fai;
+}
+
+void fai_destroy(faidx_t *fai)
+{
+ int i;
+ for (i = 0; i < fai->n; ++i) free(fai->name[i]);
+ free(fai->name);
+ kh_destroy(s, fai->hash);
+ if (fai->bgzf) bgzf_close(fai->bgzf);
+ free(fai);
+}
+
+int fai_build(const char *fn)
+{
+ char *str;
+ BGZF *bgzf;
+ FILE *fp;
+ faidx_t *fai;
+ str = (char*)calloc(strlen(fn) + 5, 1);
+ sprintf(str, "%s.fai", fn);
+ bgzf = bgzf_open(fn, "r");
+ if ( !bgzf ) {
+ fprintf(stderr, "[fai_build] fail to open the FASTA file %s\n",fn);
+ free(str);
+ return -1;
+ }
+ if ( bgzf->is_compressed ) bgzf_index_build_init(bgzf);
+ fai = fai_build_core(bgzf);
+ if ( !fai )
+ {
+ if ( bgzf->is_compressed && bgzf->is_gzip ) fprintf(stderr,"Cannot index files compressed with gzip, please use bgzip\n");
+ bgzf_close(bgzf);
+ free(str);
+ return -1;
+ }
+ if ( bgzf->is_compressed ) {
+ if (bgzf_index_dump(bgzf, fn, ".gzi") < 0) {
+ fprintf(stderr, "[fai_build] fail to make bgzf index %s.gzi\n", fn);
+ fai_destroy(fai); free(str);
+ return -1;
+ }
+ }
+ if (bgzf_close(bgzf) < 0) {
+ fprintf(stderr, "[fai_build] Error on closing %s\n", fn);
+ fai_destroy(fai); free(str);
+ return -1;
+ }
+ fp = fopen(str, "wb");
+ if ( !fp ) {
+ fprintf(stderr, "[fai_build] fail to write FASTA index %s\n",str);
+ fai_destroy(fai); free(str);
+ return -1;
+ }
+ fai_save(fai, fp);
+ fclose(fp);
+ free(str);
+ fai_destroy(fai);
+ return 0;
+}
+
+static FILE *download_and_open(const char *fn)
+{
+ const int buf_size = 1 * 1024 * 1024;
+ uint8_t *buf;
+ FILE *fp;
+ hFILE *fp_remote;
+ const char *url = fn;
+ const char *p;
+ int l = strlen(fn);
+ for (p = fn + l - 1; p >= fn; --p)
+ if (*p == '/') break;
+ fn = p + 1;
+
+ // First try to open a local copy
+ fp = fopen(fn, "r");
+ if (fp)
+ return fp;
+
+ // If failed, download from remote and open
+ fp_remote = hopen(url, "rb");
+ if (fp_remote == 0) {
+ fprintf(stderr, "[download_from_remote] fail to open remote file %s\n",url);
+ return NULL;
+ }
+ if ((fp = fopen(fn, "wb")) == 0) {
+ fprintf(stderr, "[download_from_remote] fail to create file in the working directory %s\n",fn);
+ hclose_abruptly(fp_remote);
+ return NULL;
+ }
+ buf = (uint8_t*)calloc(buf_size, 1);
+ while ((l = hread(fp_remote, buf, buf_size)) > 0)
+ fwrite(buf, 1, l, fp);
+ free(buf);
+ fclose(fp);
+ if (hclose(fp_remote) != 0)
+ fprintf(stderr, "[download_from_remote] fail to close remote file %s\n", url);
+
+ return fopen(fn, "r");
+}
+
+faidx_t *fai_load(const char *fn)
+{
+ char *str;
+ FILE *fp;
+ faidx_t *fai;
+ str = (char*)calloc(strlen(fn) + 5, 1);
+ sprintf(str, "%s.fai", fn);
+
+ if (hisremote(str))
+ {
+ fp = download_and_open(str);
+ if ( !fp )
+ {
+ fprintf(stderr, "[fai_load] failed to open remote FASTA index %s\n", str);
+ free(str);
+ return 0;
+ }
+ }
+ else
+ fp = fopen(str, "rb");
+
+ if (fp == 0) {
+ fprintf(stderr, "[fai_load] build FASTA index.\n");
+ if (fai_build(fn) < 0) {
+ free(str);
+ return 0;
+ }
+ fp = fopen(str, "rb");
+ if (fp == 0) {
+ fprintf(stderr, "[fai_load] failed to open FASTA index: %s\n", strerror(errno));
+ free(str);
+ return 0;
+ }
+ }
+
+ fai = fai_read(fp, str);
+ fclose(fp);
+ free(str);
+ if (fai == NULL) {
+ return NULL;
+ }
+
+ fai->bgzf = bgzf_open(fn, "rb");
+ if (fai->bgzf == 0) {
+ fprintf(stderr, "[fai_load] fail to open FASTA file.\n");
+ return 0;
+ }
+ if ( fai->bgzf->is_compressed==1 )
+ {
+ if ( bgzf_index_load(fai->bgzf, fn, ".gzi") < 0 )
+ {
+ fprintf(stderr, "[fai_load] failed to load .gzi index: %s[.gzi]\n", fn);
+ fai_destroy(fai);
+ return NULL;
+ }
+ }
+ return fai;
+}
+
+char *fai_fetch(const faidx_t *fai, const char *str, int *len)
+{
+ char *s;
+ int c, i, l, k, name_end;
+ khiter_t iter;
+ faidx1_t val;
+ khash_t(s) *h;
+ int beg, end;
+
+ beg = end = -1;
+ h = fai->hash;
+ name_end = l = strlen(str);
+ s = (char*)malloc(l+1);
+ // remove space
+ for (i = k = 0; i < l; ++i)
+ if (!isspace(str[i])) s[k++] = str[i];
+ s[k] = 0; l = k;
+ // determine the sequence name
+ for (i = l - 1; i >= 0; --i) if (s[i] == ':') break; // look for colon from the end
+ if (i >= 0) name_end = i;
+ if (name_end < l) { // check if this is really the end
+ int n_hyphen = 0;
+ for (i = name_end + 1; i < l; ++i) {
+ if (s[i] == '-') ++n_hyphen;
+ else if (!isdigit(s[i]) && s[i] != ',') break;
+ }
+ if (i < l || n_hyphen > 1) name_end = l; // malformated region string; then take str as the name
+ s[name_end] = 0;
+ iter = kh_get(s, h, s);
+ if (iter == kh_end(h)) { // cannot find the sequence name
+ iter = kh_get(s, h, str); // try str as the name
+ if (iter == kh_end(h)) {
+ *len = 0;
+ free(s); return 0;
+ } else s[name_end] = ':', name_end = l;
+ }
+ } else iter = kh_get(s, h, str);
+ if(iter == kh_end(h)) {
+ fprintf(stderr, "[fai_fetch] Warning - Reference %s not found in FASTA file, returning empty sequence\n", str);
+ free(s);
+ *len = -2;
+ return 0;
+ };
+ val = kh_value(h, iter);
+ // parse the interval
+ if (name_end < l) {
+ for (i = k = name_end + 1; i < l; ++i)
+ if (s[i] != ',') s[k++] = s[i];
+ s[k] = 0;
+ beg = atoi(s + name_end + 1);
+ for (i = name_end + 1; i != k; ++i) if (s[i] == '-') break;
+ end = i < k? atoi(s + i + 1) : val.len;
+ if (beg > 0) --beg;
+ } else beg = 0, end = val.len;
+ if (beg >= val.len) beg = val.len;
+ if (end >= val.len) end = val.len;
+ if (beg > end) beg = end;
+ free(s);
+
+ // now retrieve the sequence
+ int ret = bgzf_useek(fai->bgzf, val.offset + beg / val.line_blen * val.line_len + beg % val.line_blen, SEEK_SET);
+ if ( ret<0 )
+ {
+ *len = -1;
+ fprintf(stderr, "[fai_fetch] Error: fai_fetch failed. (Seeking in a compressed, .gzi unindexed, file?)\n");
+ return NULL;
+ }
+ l = 0;
+ s = (char*)malloc(end - beg + 2);
+ while ( (c=bgzf_getc(fai->bgzf))>=0 && l < end - beg )
+ if (isgraph(c)) s[l++] = c;
+ s[l] = '\0';
+ *len = l;
+ return s;
+}
+
+int faidx_fetch_nseq(const faidx_t *fai)
+{
+ return fai->n;
+}
+
+int faidx_nseq(const faidx_t *fai)
+{
+ return fai->n;
+}
+
+const char *faidx_iseq(const faidx_t *fai, int i)
+{
+ return fai->name[i];
+}
+
+int faidx_seq_len(const faidx_t *fai, const char *seq)
+{
+ khint_t k = kh_get(s, fai->hash, seq);
+ if ( k == kh_end(fai->hash) ) return -1;
+ return kh_val(fai->hash, k).len;
+}
+
+char *faidx_fetch_seq(const faidx_t *fai, const char *c_name, int p_beg_i, int p_end_i, int *len)
+{
+ int l, c;
+ khiter_t iter;
+ faidx1_t val;
+ char *seq=NULL;
+
+ // Adjust position
+ iter = kh_get(s, fai->hash, c_name);
+ if (iter == kh_end(fai->hash))
+ {
+ *len = -2;
+ fprintf(stderr, "[fai_fetch_seq] The sequence \"%s\" not found\n", c_name);
+ return NULL;
+ }
+ val = kh_value(fai->hash, iter);
+ if(p_end_i < p_beg_i) p_beg_i = p_end_i;
+ if(p_beg_i < 0) p_beg_i = 0;
+ else if(val.len <= p_beg_i) p_beg_i = val.len - 1;
+ if(p_end_i < 0) p_end_i = 0;
+ else if(val.len <= p_end_i) p_end_i = val.len - 1;
+
+ // Now retrieve the sequence
+ int ret = bgzf_useek(fai->bgzf, val.offset + p_beg_i / val.line_blen * val.line_len + p_beg_i % val.line_blen, SEEK_SET);
+ if ( ret<0 )
+ {
+ *len = -1;
+ fprintf(stderr, "[fai_fetch_seq] Error: fai_fetch failed. (Seeking in a compressed, .gzi unindexed, file?)\n");
+ return NULL;
+ }
+ l = 0;
+ seq = (char*)malloc(p_end_i - p_beg_i + 2);
+ while ( (c=bgzf_getc(fai->bgzf))>=0 && l < p_end_i - p_beg_i + 1)
+ if (isgraph(c)) seq[l++] = c;
+ seq[l] = '\0';
+ *len = l;
+ return seq;
+}
+
+int faidx_has_seq(const faidx_t *fai, const char *seq)
+{
+ khiter_t iter = kh_get(s, fai->hash, seq);
+ if (iter == kh_end(fai->hash)) return 0;
+ return 1;
+}
+
--- /dev/null
+/* hfile.c -- buffered low-level input/output streams.
+
+ Copyright (C) 2013-2016 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <stdlib.h>
+#include <string.h>
+#include <errno.h>
+
+#include <pthread.h>
+
+#include "htslib/hfile.h"
+#include "hfile_internal.h"
+
+#ifndef ENOTSUP
+#define ENOTSUP EINVAL
+#endif
+#ifndef EOVERFLOW
+#define EOVERFLOW ERANGE
+#endif
+#ifndef EPROTONOSUPPORT
+#define EPROTONOSUPPORT ENOSYS
+#endif
+
+/* hFILE fields are used as follows:
+
+ char *buffer; // Pointer to the start of the I/O buffer
+ char *begin; // First not-yet-read character / unused position
+ char *end; // First unfilled/unfillable position
+ char *limit; // Pointer to the first position past the buffer
+
+ const hFILE_backend *backend; // Methods to refill/flush I/O buffer
+
+ off_t offset; // Offset within the stream of buffer position 0
+ unsigned at_eof:1;// For reading, whether EOF has been seen
+ int has_errno; // Error number from the last failure on this stream
+
+For reading, begin is the first unread character in the buffer and end is the
+first unfilled position:
+
+ -----------ABCDEFGHIJKLMNO---------------
+ ^buffer ^begin ^end ^limit
+
+For writing, begin is the first unused position and end is unused so remains
+equal to buffer:
+
+ ABCDEFGHIJKLMNOPQRSTUVWXYZ---------------
+ ^buffer ^begin ^limit
+ ^end
+
+Thus if begin > end then there is a non-empty write buffer, if begin < end
+then there is a non-empty read buffer, and if begin == end then both buffers
+are empty. In all cases, the stream's file position indicator corresponds
+to the position pointed to by begin. */
+
+hFILE *hfile_init(size_t struct_size, const char *mode, size_t capacity)
+{
+ hFILE *fp = (hFILE *) malloc(struct_size);
+ if (fp == NULL) goto error;
+
+ if (capacity == 0) capacity = 32768;
+ // FIXME For now, clamp input buffer sizes so mpileup doesn't eat memory
+ if (strchr(mode, 'r') && capacity > 32768) capacity = 32768;
+
+ fp->buffer = (char *) malloc(capacity);
+ if (fp->buffer == NULL) goto error;
+
+ fp->begin = fp->end = fp->buffer;
+ fp->limit = &fp->buffer[capacity];
+
+ fp->offset = 0;
+ fp->at_eof = 0;
+ fp->has_errno = 0;
+ return fp;
+
+error:
+ hfile_destroy(fp);
+ return NULL;
+}
+
+void hfile_destroy(hFILE *fp)
+{
+ int save = errno;
+ if (fp) free(fp->buffer);
+ free(fp);
+ errno = save;
+}
+
+static inline int writebuffer_is_nonempty(hFILE *fp)
+{
+ return fp->begin > fp->end;
+}
+
+/* Refills the read buffer from the backend (once, so may only partially
+ fill the buffer), returning the number of additional characters read
+ (which might be 0), or negative when an error occurred. */
+static ssize_t refill_buffer(hFILE *fp)
+{
+ ssize_t n;
+
+ // Move any unread characters to the start of the buffer
+ if (fp->begin > fp->buffer) {
+ fp->offset += fp->begin - fp->buffer;
+ memmove(fp->buffer, fp->begin, fp->end - fp->begin);
+ fp->end = &fp->buffer[fp->end - fp->begin];
+ fp->begin = fp->buffer;
+ }
+
+ // Read into the available buffer space at fp->[end,limit)
+ if (fp->at_eof || fp->end == fp->limit) n = 0;
+ else {
+ n = fp->backend->read(fp, fp->end, fp->limit - fp->end);
+ if (n < 0) { fp->has_errno = errno; return n; }
+ else if (n == 0) fp->at_eof = 1;
+ }
+
+ fp->end += n;
+ return n;
+}
+
+/* Called only from hgetc(), when our buffer is empty. */
+int hgetc2(hFILE *fp)
+{
+ return (refill_buffer(fp) > 0)? (unsigned char) *(fp->begin++) : EOF;
+}
+
+ssize_t hpeek(hFILE *fp, void *buffer, size_t nbytes)
+{
+ size_t n = fp->end - fp->begin;
+ while (n < nbytes) {
+ ssize_t ret = refill_buffer(fp);
+ if (ret < 0) return ret;
+ else if (ret == 0) break;
+ else n += ret;
+ }
+
+ if (n > nbytes) n = nbytes;
+ memcpy(buffer, fp->begin, n);
+ return n;
+}
+
+/* Called only from hread(); when called, our buffer is empty and nread bytes
+ have already been placed in the destination buffer. */
+ssize_t hread2(hFILE *fp, void *destv, size_t nbytes, size_t nread)
+{
+ const size_t capacity = fp->limit - fp->buffer;
+ char *dest = (char *) destv;
+ dest += nread, nbytes -= nread;
+
+ // Read large requests directly into the destination buffer
+ while (nbytes * 2 >= capacity && !fp->at_eof) {
+ ssize_t n = fp->backend->read(fp, dest, nbytes);
+ if (n < 0) { fp->has_errno = errno; return n; }
+ else if (n == 0) fp->at_eof = 1;
+ fp->offset += n;
+ dest += n, nbytes -= n;
+ nread += n;
+ }
+
+ while (nbytes > 0 && !fp->at_eof) {
+ size_t n;
+ ssize_t ret = refill_buffer(fp);
+ if (ret < 0) return ret;
+
+ n = fp->end - fp->begin;
+ if (n > nbytes) n = nbytes;
+ memcpy(dest, fp->begin, n);
+ fp->begin += n;
+ dest += n, nbytes -= n;
+ nread += n;
+ }
+
+ return nread;
+}
+
+/* Flushes the write buffer, fp->[buffer,begin), out through the backend
+ returning 0 on success or negative if an error occurred. */
+static ssize_t flush_buffer(hFILE *fp)
+{
+ const char *buffer = fp->buffer;
+ while (buffer < fp->begin) {
+ ssize_t n = fp->backend->write(fp, buffer, fp->begin - buffer);
+ if (n < 0) { fp->has_errno = errno; return n; }
+ buffer += n;
+ fp->offset += n;
+ }
+
+ fp->begin = fp->buffer; // Leave the buffer empty
+ return 0;
+}
+
+int hflush(hFILE *fp)
+{
+ if (flush_buffer(fp) < 0) return EOF;
+ if (fp->backend->flush) {
+ if (fp->backend->flush(fp) < 0) { fp->has_errno = errno; return EOF; }
+ }
+ return 0;
+}
+
+/* Called only from hputc(), when our buffer is already full. */
+int hputc2(int c, hFILE *fp)
+{
+ if (flush_buffer(fp) < 0) return EOF;
+ *(fp->begin++) = c;
+ return c;
+}
+
+/* Called only from hwrite() and hputs2(); when called, our buffer is full and
+ ncopied bytes from the source have already been copied to our buffer. */
+ssize_t hwrite2(hFILE *fp, const void *srcv, size_t totalbytes, size_t ncopied)
+{
+ const char *src = (const char *) srcv;
+ ssize_t ret;
+ const size_t capacity = fp->limit - fp->buffer;
+ size_t remaining = totalbytes - ncopied;
+ src += ncopied;
+
+ ret = flush_buffer(fp);
+ if (ret < 0) return ret;
+
+ // Write large blocks out directly from the source buffer
+ while (remaining * 2 >= capacity) {
+ ssize_t n = fp->backend->write(fp, src, remaining);
+ if (n < 0) { fp->has_errno = errno; return n; }
+ fp->offset += n;
+ src += n, remaining -= n;
+ }
+
+ // Just buffer any remaining characters
+ memcpy(fp->begin, src, remaining);
+ fp->begin += remaining;
+
+ return totalbytes;
+}
+
+/* Called only from hputs(), when our buffer is already full. */
+int hputs2(const char *text, size_t totalbytes, size_t ncopied, hFILE *fp)
+{
+ return (hwrite2(fp, text, totalbytes, ncopied) >= 0)? 0 : EOF;
+}
+
+off_t hseek(hFILE *fp, off_t offset, int whence)
+{
+ off_t curpos, pos;
+
+ if (writebuffer_is_nonempty(fp)) {
+ int ret = flush_buffer(fp);
+ if (ret < 0) return ret;
+ }
+
+ curpos = htell(fp);
+
+ // Relative offsets are given relative to the hFILE's stream position,
+ // which may differ from the backend's physical position due to buffering
+ // read-ahead. Correct for this by converting to an absolute position.
+ if (whence == SEEK_CUR) {
+ if (curpos + offset < 0) {
+ // Either a negative offset resulted in a position before the
+ // start of the file, or we overflowed when given a positive offset
+ fp->has_errno = errno = (offset < 0)? EINVAL : EOVERFLOW;
+ return -1;
+ }
+
+ whence = SEEK_SET;
+ offset = curpos + offset;
+ }
+
+ // TODO Avoid seeking if the desired position is within our read buffer
+
+ pos = fp->backend->seek(fp, offset, whence);
+ if (pos < 0) { fp->has_errno = errno; return pos; }
+
+ // Seeking succeeded, so discard any non-empty read buffer
+ fp->begin = fp->end = fp->buffer;
+ fp->at_eof = 0;
+
+ fp->offset = pos;
+ return pos;
+}
+
+int hclose(hFILE *fp)
+{
+ int err = fp->has_errno;
+
+ if (writebuffer_is_nonempty(fp) && hflush(fp) < 0) err = fp->has_errno;
+ if (fp->backend->close(fp) < 0) err = errno;
+ hfile_destroy(fp);
+
+ if (err) {
+ errno = err;
+ return EOF;
+ }
+ else return 0;
+}
+
+void hclose_abruptly(hFILE *fp)
+{
+ int save = errno;
+ if (fp->backend->close(fp) < 0) { /* Ignore subsequent errors */ }
+ hfile_destroy(fp);
+ errno = save;
+}
+
+
+/***************************
+ * File descriptor backend *
+ ***************************/
+
+#ifndef _WIN32
+#include <sys/socket.h>
+#include <sys/stat.h>
+#define HAVE_STRUCT_STAT_ST_BLKSIZE
+#else
+#include <winsock2.h>
+#define HAVE_CLOSESOCKET
+#define HAVE_SETMODE
+#endif
+#include <fcntl.h>
+#include <unistd.h>
+
+/* For Unix, it doesn't matter whether a file descriptor is a socket.
+ However Windows insists on send()/recv() and its own closesocket()
+ being used when fd happens to be a socket. */
+
+typedef struct {
+ hFILE base;
+ int fd;
+ unsigned is_socket:1;
+} hFILE_fd;
+
+static ssize_t fd_read(hFILE *fpv, void *buffer, size_t nbytes)
+{
+ hFILE_fd *fp = (hFILE_fd *) fpv;
+ ssize_t n;
+ do {
+ n = fp->is_socket? recv(fp->fd, buffer, nbytes, 0)
+ : read(fp->fd, buffer, nbytes);
+ } while (n < 0 && errno == EINTR);
+ return n;
+}
+
+static ssize_t fd_write(hFILE *fpv, const void *buffer, size_t nbytes)
+{
+ hFILE_fd *fp = (hFILE_fd *) fpv;
+ ssize_t n;
+ do {
+ n = fp->is_socket? send(fp->fd, buffer, nbytes, 0)
+ : write(fp->fd, buffer, nbytes);
+ } while (n < 0 && errno == EINTR);
+ return n;
+}
+
+static off_t fd_seek(hFILE *fpv, off_t offset, int whence)
+{
+ hFILE_fd *fp = (hFILE_fd *) fpv;
+ return lseek(fp->fd, offset, whence);
+}
+
+static int fd_flush(hFILE *fpv)
+{
+ hFILE_fd *fp = (hFILE_fd *) fpv;
+ int ret;
+ do {
+#ifdef HAVE_FDATASYNC
+ ret = fdatasync(fp->fd);
+#else
+ ret = fsync(fp->fd);
+#endif
+ // Ignore invalid-for-fsync(2) errors due to being, e.g., a pipe,
+ // and operation-not-supported errors (Mac OS X)
+ if (ret < 0 && (errno == EINVAL || errno == ENOTSUP)) ret = 0;
+ } while (ret < 0 && errno == EINTR);
+ return ret;
+}
+
+static int fd_close(hFILE *fpv)
+{
+ hFILE_fd *fp = (hFILE_fd *) fpv;
+ int ret;
+ do {
+#ifdef HAVE_CLOSESOCKET
+ ret = fp->is_socket? closesocket(fp->fd) : close(fp->fd);
+#else
+ ret = close(fp->fd);
+#endif
+ } while (ret < 0 && errno == EINTR);
+ return ret;
+}
+
+static const struct hFILE_backend fd_backend =
+{
+ fd_read, fd_write, fd_seek, fd_flush, fd_close
+};
+
+static size_t blksize(int fd)
+{
+#ifdef HAVE_STRUCT_STAT_ST_BLKSIZE
+ struct stat sbuf;
+ if (fstat(fd, &sbuf) != 0) return 0;
+ return sbuf.st_blksize;
+#else
+ return 0;
+#endif
+}
+
+static hFILE *hopen_fd(const char *filename, const char *mode)
+{
+ hFILE_fd *fp = NULL;
+ int fd = open(filename, hfile_oflags(mode), 0666);
+ if (fd < 0) goto error;
+
+ fp = (hFILE_fd *) hfile_init(sizeof (hFILE_fd), mode, blksize(fd));
+ if (fp == NULL) goto error;
+
+ fp->fd = fd;
+ fp->is_socket = 0;
+ fp->base.backend = &fd_backend;
+ return &fp->base;
+
+error:
+ if (fd >= 0) { int save = errno; (void) close(fd); errno = save; }
+ hfile_destroy((hFILE *) fp);
+ return NULL;
+}
+
+hFILE *hdopen(int fd, const char *mode)
+{
+ hFILE_fd *fp = (hFILE_fd*) hfile_init(sizeof (hFILE_fd), mode, blksize(fd));
+ if (fp == NULL) return NULL;
+
+ fp->fd = fd;
+ fp->is_socket = (strchr(mode, 's') != NULL);
+ fp->base.backend = &fd_backend;
+ return &fp->base;
+}
+
+static hFILE *hopen_fd_fileuri(const char *url, const char *mode)
+{
+ if (strncmp(url, "file://localhost/", 17) == 0) url += 16;
+ else if (strncmp(url, "file:///", 8) == 0) url += 7;
+ else { errno = EPROTONOSUPPORT; return NULL; }
+
+ return hopen_fd(url, mode);
+}
+
+static hFILE *hopen_fd_stdinout(const char *mode)
+{
+ int fd = (strchr(mode, 'r') != NULL)? STDIN_FILENO : STDOUT_FILENO;
+#if defined HAVE_SETMODE && defined O_BINARY
+ if (setmode(fd, O_BINARY) < 0) return NULL;
+#endif
+ return hdopen(fd, mode);
+}
+
+int hfile_oflags(const char *mode)
+{
+ int rdwr = 0, flags = 0;
+ const char *s;
+ for (s = mode; *s; s++)
+ switch (*s) {
+ case 'r': rdwr = O_RDONLY; break;
+ case 'w': rdwr = O_WRONLY; flags |= O_CREAT | O_TRUNC; break;
+ case 'a': rdwr = O_WRONLY; flags |= O_CREAT | O_APPEND; break;
+ case '+': rdwr = O_RDWR; break;
+#ifdef O_CLOEXEC
+ case 'e': flags |= O_CLOEXEC; break;
+#endif
+#ifdef O_EXCL
+ case 'x': flags |= O_EXCL; break;
+#endif
+ default: break;
+ }
+
+#ifdef O_BINARY
+ flags |= O_BINARY;
+#endif
+
+ return rdwr | flags;
+}
+
+
+/*********************
+ * In-memory backend *
+ *********************/
+
+typedef struct {
+ hFILE base;
+ const char *buffer;
+ size_t length, pos;
+} hFILE_mem;
+
+static ssize_t mem_read(hFILE *fpv, void *buffer, size_t nbytes)
+{
+ hFILE_mem *fp = (hFILE_mem *) fpv;
+ size_t avail = fp->length - fp->pos;
+ if (nbytes > avail) nbytes = avail;
+ memcpy(buffer, fp->buffer + fp->pos, nbytes);
+ fp->pos += nbytes;
+ return nbytes;
+}
+
+static off_t mem_seek(hFILE *fpv, off_t offset, int whence)
+{
+ hFILE_mem *fp = (hFILE_mem *) fpv;
+ size_t absoffset = (offset >= 0)? offset : -offset;
+ size_t origin;
+
+ switch (whence) {
+ case SEEK_SET: origin = 0; break;
+ case SEEK_CUR: origin = fp->pos; break;
+ case SEEK_END: origin = fp->length; break;
+ default: errno = EINVAL; return -1;
+ }
+
+ if ((offset < 0 && absoffset > origin) ||
+ (offset >= 0 && absoffset > fp->length - origin)) {
+ errno = EINVAL;
+ return -1;
+ }
+
+ fp->pos = origin + offset;
+ return fp->pos;
+}
+
+static int mem_close(hFILE *fpv)
+{
+ return 0;
+}
+
+static const struct hFILE_backend mem_backend =
+{
+ mem_read, NULL, mem_seek, NULL, mem_close
+};
+
+static hFILE *hopen_mem(const char *data, const char *mode)
+{
+ if (strncmp(data, "data:", 5) == 0) data += 5;
+
+ // TODO Implement write modes, which will require memory allocation
+ if (strchr(mode, 'r') == NULL) { errno = EINVAL; return NULL; }
+
+ hFILE_mem *fp = (hFILE_mem *) hfile_init(sizeof (hFILE_mem), mode, 0);
+ if (fp == NULL) return NULL;
+
+ fp->buffer = data;
+ fp->length = strlen(data);
+ fp->pos = 0;
+ fp->base.backend = &mem_backend;
+ return &fp->base;
+}
+
+
+/*****************************************
+ * Plugin and hopen() backend dispatcher *
+ *****************************************/
+
+#include <ctype.h>
+
+#include "hts_internal.h"
+#include "htslib/khash.h"
+
+KHASH_MAP_INIT_STR(scheme_string, const struct hFILE_scheme_handler *);
+static khash_t(scheme_string) *schemes = NULL;
+
+struct hFILE_plugin_list {
+ struct hFILE_plugin plugin;
+ struct hFILE_plugin_list *next;
+};
+
+static struct hFILE_plugin_list *plugins = NULL;
+static pthread_mutex_t plugins_lock = PTHREAD_MUTEX_INITIALIZER;
+
+static void hfile_exit()
+{
+ pthread_mutex_lock(&plugins_lock);
+
+ kh_destroy(scheme_string, schemes);
+
+ while (plugins != NULL) {
+ struct hFILE_plugin_list *p = plugins;
+ if (p->plugin.destroy) p->plugin.destroy();
+#ifdef ENABLE_PLUGINS
+ if (p->plugin.obj) close_plugin(p->plugin.obj);
+#endif
+ plugins = p->next;
+ free(p);
+ }
+
+ pthread_mutex_unlock(&plugins_lock);
+ pthread_mutex_destroy(&plugins_lock);
+}
+
+void hfile_add_scheme_handler(const char *scheme,
+ const struct hFILE_scheme_handler *handler)
+{
+ int absent;
+ khint_t k = kh_put(scheme_string, schemes, scheme, &absent);
+ if (absent || handler->priority > kh_value(schemes, k)->priority) {
+ kh_value(schemes, k) = handler;
+ }
+}
+
+static int init_add_plugin(void *obj, int (*init)(struct hFILE_plugin *),
+ const char *pluginname)
+{
+ struct hFILE_plugin_list *p = malloc (sizeof (struct hFILE_plugin_list));
+ if (p == NULL) abort();
+
+ p->plugin.api_version = 1;
+ p->plugin.obj = obj;
+ p->plugin.name = NULL;
+ p->plugin.destroy = NULL;
+
+ int ret = (*init)(&p->plugin);
+
+ if (ret != 0) {
+ if (hts_verbose >= 4)
+ fprintf(stderr, "[W::load_hfile_plugins] "
+ "initialisation failed for plugin \"%s\": %d\n",
+ pluginname, ret);
+ free(p);
+ return ret;
+ }
+
+ if (hts_verbose >= 5)
+ fprintf(stderr, "[M::load_hfile_plugins] loaded \"%s\"\n", pluginname);
+
+ p->next = plugins, plugins = p;
+ return 0;
+}
+
+static void load_hfile_plugins()
+{
+ static const struct hFILE_scheme_handler
+ data = { hopen_mem, hfile_always_local, "built-in", 80 },
+ file = { hopen_fd_fileuri, hfile_always_local, "built-in", 80 };
+
+ schemes = kh_init(scheme_string);
+ if (schemes == NULL) abort();
+
+ hfile_add_scheme_handler("data", &data);
+ hfile_add_scheme_handler("file", &file);
+ init_add_plugin(NULL, hfile_plugin_init_net, "knetfile");
+
+#ifdef ENABLE_PLUGINS
+ struct hts_path_itr path;
+ const char *pluginname;
+ hts_path_itr_setup(&path, NULL, NULL, "hfile_", 6, NULL, 0);
+ while ((pluginname = hts_path_itr_next(&path)) != NULL) {
+ void *obj;
+ int (*init)(struct hFILE_plugin *) = (int (*)(struct hFILE_plugin *))
+ load_plugin(&obj, pluginname, "hfile_plugin_init");
+
+ if (init) {
+ if (init_add_plugin(obj, init, pluginname) != 0)
+ close_plugin(obj);
+ }
+ }
+#else
+
+#ifdef HAVE_IRODS
+ init_add_plugin(NULL, hfile_plugin_init_irods, "iRODS");
+#endif
+#ifdef HAVE_LIBCURL
+ init_add_plugin(NULL, hfile_plugin_init_libcurl, "libcurl");
+#endif
+
+#endif
+
+ // In the unlikely event atexit() fails, it's better to succeed here and
+ // carry on; then eventually when the program exits, we'll merely close
+ // down the plugins uncleanly, as if we had aborted.
+ (void) atexit(hfile_exit);
+}
+
+/* A filename like "foo:bar" in which we don't recognise the scheme is
+ either an ordinary file or an indication of a missing or broken plugin.
+ Try to open it as an ordinary file; but if there's no such file, set
+ errno distinctively to make the plugin issue apparent. */
+static hFILE *hopen_unknown_scheme(const char *fname, const char *mode)
+{
+ hFILE *fp = hopen_fd(fname, mode);
+ if (fp == NULL && errno == ENOENT) errno = EPROTONOSUPPORT;
+ return fp;
+}
+
+/* Returns the appropriate handler, or NULL if the string isn't an URL. */
+static const struct hFILE_scheme_handler *find_scheme_handler(const char *s)
+{
+ static const struct hFILE_scheme_handler unknown_scheme =
+ { hopen_unknown_scheme, hfile_always_local, "built-in", 0 };
+
+ char scheme[12];
+ int i;
+
+ for (i = 0; i < sizeof scheme; i++)
+ if (isalnum(s[i]) || s[i] == '+' || s[i] == '-' || s[i] == '.')
+ scheme[i] = tolower(s[i]);
+ else if (s[i] == ':') break;
+ else return NULL;
+
+ if (i == 0 || i >= sizeof scheme) return NULL;
+ scheme[i] = '\0';
+
+ pthread_mutex_lock(&plugins_lock);
+ if (! schemes) load_hfile_plugins();
+ pthread_mutex_unlock(&plugins_lock);
+
+ khint_t k = kh_get(scheme_string, schemes, scheme);
+ return (k != kh_end(schemes))? kh_value(schemes, k) : &unknown_scheme;
+}
+
+hFILE *hopen(const char *fname, const char *mode)
+{
+ const struct hFILE_scheme_handler *handler = find_scheme_handler(fname);
+ if (handler) return handler->open(fname, mode);
+ else if (strcmp(fname, "-") == 0) return hopen_fd_stdinout(mode);
+ else return hopen_fd(fname, mode);
+}
+
+int hfile_always_local (const char *fname) { return 0; }
+int hfile_always_remote(const char *fname) { return 1; }
+
+int hisremote(const char *fname)
+{
+ const struct hFILE_scheme_handler *handler = find_scheme_handler(fname);
+ return handler? handler->isremote(fname) : 0;
+}
--- /dev/null
+/* hfile_internal.h -- internal parts of low-level input/output streams.
+
+ Copyright (C) 2013-2015 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HFILE_INTERNAL_H
+#define HFILE_INTERNAL_H
+
+#include "htslib/hfile.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+struct hFILE_backend {
+ /* As per read(2), returning the number of bytes read (possibly 0) or
+ negative (and setting errno) on errors. Front-end code will call this
+ repeatedly if necessary to attempt to get the desired byte count. */
+ ssize_t (*read)(hFILE *fp, void *buffer, size_t nbytes) HTS_RESULT_USED;
+
+ /* As per write(2), returning the number of bytes written or negative (and
+ setting errno) on errors. Front-end code will call this repeatedly if
+ necessary until the desired block is written or an error occurs. */
+ ssize_t (*write)(hFILE *fp, const void *buffer, size_t nbytes)
+ HTS_RESULT_USED;
+
+ /* As per lseek(2), returning the resulting offset within the stream or
+ negative (and setting errno) on errors. */
+ off_t (*seek)(hFILE *fp, off_t offset, int whence) HTS_RESULT_USED;
+
+ /* Performs low-level flushing, if any, e.g., fsync(2); for writing streams
+ only. Returns 0 for success or negative (and sets errno) on errors. */
+ int (*flush)(hFILE *fp) HTS_RESULT_USED;
+
+ /* Closes the underlying stream (for output streams, the buffer will
+ already have been flushed), returning 0 for success or negative (and
+ setting errno) on errors, as per close(2). */
+ int (*close)(hFILE *fp) HTS_RESULT_USED;
+};
+
+/* May be called by hopen_*() functions to decode a fopen()-style mode into
+ open(2)-style flags. */
+int hfile_oflags(const char *mode);
+
+/* Must be called by hopen_*() functions to allocate the hFILE struct and set
+ up its base. Capacity is a suggested buffer size (e.g., via fstat(2))
+ or 0 for a default-sized buffer. */
+hFILE *hfile_init(size_t struct_size, const char *mode, size_t capacity);
+
+/* May be called by hopen_*() functions to undo the effects of hfile_init()
+ in the event opening the stream subsequently fails. (This is safe to use
+ even if fp is NULL. This takes care to preserve errno.) */
+void hfile_destroy(hFILE *fp);
+
+
+struct hFILE_scheme_handler {
+ /* Opens a stream when dispatched by hopen(); should call hfile_init()
+ to malloc a struct "derived" from hFILE and initialise it appropriately,
+ including setting base.backend to its own backend vector. */
+ hFILE *(*open)(const char *filename, const char *mode) HTS_RESULT_USED;
+
+ /* Returns whether the URL denotes remote storage when dispatched by
+ hisremote(). For simple cases, use one of hfile_always_*() below. */
+ int (*isremote)(const char *filename) HTS_RESULT_USED;
+
+ /* The name of the plugin or other code providing this handler. */
+ const char *provider;
+
+ /* If multiple handlers are registered for the same scheme, the one with
+ the highest priority is used; range is 0 (lowest) to 100 (highest). */
+ int priority;
+};
+
+/* May be used as an isremote() function in simple cases. */
+extern int hfile_always_local (const char *fname);
+extern int hfile_always_remote(const char *fname);
+
+/* Should be called by plugins for each URL scheme they wish to handle. */
+void hfile_add_scheme_handler(const char *scheme,
+ const struct hFILE_scheme_handler *handler);
+
+struct hFILE_plugin {
+ /* On entry, HTSlib's plugin API version (currently 1). */
+ int api_version;
+
+ /* On entry, the plugin's handle as returned by dlopen() etc. */
+ void *obj;
+
+ /* The plugin should fill this in with its (human-readable) name. */
+ const char *name;
+
+ /* The plugin may wish to fill in a function to be called on closing. */
+ void (*destroy)(void);
+};
+
+#ifdef ENABLE_PLUGINS
+#define PLUGIN_GLOBAL(identifier,suffix) identifier
+
+/* Plugins must define an entry point with this signature. */
+extern int hfile_plugin_init(struct hFILE_plugin *self);
+
+#else
+#define PLUGIN_GLOBAL(identifier,suffix) identifier##suffix
+
+/* Only plugins distributed within the HTSlib source that might be built
+ even with --disable-plugins need to use PLUGIN_GLOBAL and be listed here;
+ others can simply define hfile_plugin_init(). */
+
+extern int hfile_plugin_init_irods(struct hFILE_plugin *self);
+extern int hfile_plugin_init_libcurl(struct hFILE_plugin *self);
+#endif
+
+/* This one is never built as a separate plugin. */
+extern int hfile_plugin_init_net(struct hFILE_plugin *self);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* hfile_irods.c -- iRODS backend for low-level file streams.
+
+ Copyright (C) 2013, 2015 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <signal.h>
+#include <stdlib.h>
+#include <string.h>
+#include <errno.h>
+
+#include "hfile_internal.h"
+#include "htslib/hts.h" // for hts_version() and hts_verbose
+#include "htslib/kstring.h"
+
+#include <rcConnect.h>
+#include <rcMisc.h>
+#include <dataObjOpen.h>
+#include <dataObjRead.h>
+#include <dataObjWrite.h>
+#include <dataObjLseek.h>
+#include <dataObjClose.h>
+
+typedef struct {
+ hFILE base;
+ int descriptor;
+} hFILE_irods;
+
+static int status_errno(int status)
+{
+ switch (status) {
+ case SYS_NO_API_PRIV: return EACCES;
+ case SYS_MALLOC_ERR: return ENOMEM;
+ case SYS_OUT_OF_FILE_DESC: return ENFILE;
+ case SYS_BAD_FILE_DESCRIPTOR: return EBADF;
+ case CAT_NO_ACCESS_PERMISSION: return EACCES;
+ case CAT_INVALID_AUTHENTICATION: return EACCES;
+ case CAT_NO_ROWS_FOUND: return ENOENT;
+ case CATALOG_ALREADY_HAS_ITEM_BY_THAT_NAME: return EEXIST;
+ default: return EIO;
+ }
+}
+
+static void set_errno(int status)
+{
+ int err = abs(status) % 1000;
+ errno = err? err : status_errno(status);
+}
+
+static struct {
+ rcComm_t *conn;
+ rodsEnv env;
+} irods = { NULL };
+
+static void irods_exit()
+{
+ if (irods.conn) { (void) rcDisconnect(irods.conn); }
+ irods.conn = NULL;
+}
+
+static int irods_init()
+{
+ kstring_t useragent = { 0, 0, NULL };
+ struct sigaction pipehandler;
+ rErrMsg_t err;
+ int ret, pipehandler_ret;
+
+ if (hts_verbose >= 5) rodsLogLevel(hts_verbose);
+
+ ret = getRodsEnv(&irods.env);
+ if (ret < 0) goto error;
+
+ // Set iRODS User-Agent, if our caller hasn't already done so.
+ kputs("htslib/", &useragent);
+ kputs(hts_version(), &useragent);
+ (void) setenv(SP_OPTION, useragent.s, 0);
+ free(useragent.s);
+
+ // Prior to iRODS 4.1, rcConnect() (even if it fails) installs its own
+ // SIGPIPE handler, which just prints a message and otherwise ignores the
+ // signal. Most actual SIGPIPEs encountered will pertain to e.g. stdout
+ // rather than iRODS's connection, so we save and restore the existing
+ // state (by default, termination; or as already set by our caller).
+ pipehandler_ret = sigaction(SIGPIPE, NULL, &pipehandler);
+
+ irods.conn = rcConnect(irods.env.rodsHost, irods.env.rodsPort,
+ irods.env.rodsUserName, irods.env.rodsZone,
+ NO_RECONN, &err);
+ if (pipehandler_ret == 0) sigaction(SIGPIPE, &pipehandler, NULL);
+ if (irods.conn == NULL) { ret = err.status; goto error; }
+
+ if (strcmp(irods.env.rodsUserName, PUBLIC_USER_NAME) != 0) {
+#if defined IRODS_VERSION_INTEGER && IRODS_VERSION_INTEGER >= 4000000
+ ret = clientLogin(irods.conn, NULL, NULL);
+#else
+ ret = clientLogin(irods.conn);
+#endif
+ if (ret != 0) goto error;
+ }
+
+ return 0;
+
+error:
+ if (irods.conn) { (void) rcDisconnect(irods.conn); }
+ irods.conn = NULL;
+ set_errno(ret);
+ return -1;
+}
+
+static ssize_t irods_read(hFILE *fpv, void *buffer, size_t nbytes)
+{
+ hFILE_irods *fp = (hFILE_irods *) fpv;
+ openedDataObjInp_t args;
+ bytesBuf_t buf;
+ int ret;
+
+ memset(&args, 0, sizeof args);
+ args.l1descInx = fp->descriptor;
+ args.len = nbytes;
+
+ buf.buf = buffer;
+ buf.len = nbytes;
+
+ ret = rcDataObjRead(irods.conn, &args, &buf);
+ if (ret < 0) set_errno(ret);
+ return ret;
+}
+
+static ssize_t irods_write(hFILE *fpv, const void *buffer, size_t nbytes)
+{
+ hFILE_irods *fp = (hFILE_irods *) fpv;
+ openedDataObjInp_t args;
+ bytesBuf_t buf;
+ int ret;
+
+ memset(&args, 0, sizeof args);
+ args.l1descInx = fp->descriptor;
+ args.len = nbytes;
+
+ buf.buf = (void *) buffer; // ...the iRODS API is not const-correct here
+ buf.len = nbytes;
+
+ ret = rcDataObjWrite(irods.conn, &args, &buf);
+ if (ret < 0) set_errno(ret);
+ return ret;
+}
+
+static off_t irods_seek(hFILE *fpv, off_t offset, int whence)
+{
+ hFILE_irods *fp = (hFILE_irods *) fpv;
+ openedDataObjInp_t args;
+ fileLseekOut_t *out = NULL;
+ int ret;
+
+ memset(&args, 0, sizeof args);
+ args.l1descInx = fp->descriptor;
+ args.offset = offset;
+ args.whence = whence;
+
+ ret = rcDataObjLseek(irods.conn, &args, &out);
+
+ if (out) { offset = out->offset; free(out); }
+ else offset = -1;
+ if (ret < 0) { set_errno(ret); return -1; }
+ return offset;
+}
+
+static int irods_close(hFILE *fpv)
+{
+ hFILE_irods *fp = (hFILE_irods *) fpv;
+ openedDataObjInp_t args;
+ int ret;
+
+ memset(&args, 0, sizeof args);
+ args.l1descInx = fp->descriptor;
+
+ ret = rcDataObjClose(irods.conn, &args);
+ if (ret < 0) set_errno(ret);
+ return ret;
+}
+
+static const struct hFILE_backend irods_backend =
+{
+ irods_read, irods_write, irods_seek, NULL, irods_close
+};
+
+hFILE *hopen_irods(const char *filename, const char *mode)
+{
+ hFILE_irods *fp;
+ rodsPath_t path;
+ dataObjInp_t args;
+ int ret;
+
+ // Initialise the iRODS connection if this is the first use.
+ if (irods.conn == NULL) { if (irods_init() < 0) return NULL; }
+
+ if (strncmp(filename, "irods:", 6) == 0) filename += 6;
+ else { errno = EINVAL; return NULL; }
+
+ fp = (hFILE_irods *) hfile_init(sizeof (hFILE_irods), mode, 0);
+ if (fp == NULL) return NULL;
+
+ strncpy(path.inPath, filename, MAX_NAME_LEN-1);
+ path.inPath[MAX_NAME_LEN-1] = '\0';
+
+ ret = parseRodsPath(&path, &irods.env);
+ if (ret < 0) goto error;
+
+ memset(&args, 0, sizeof args);
+ strcpy(args.objPath, path.outPath);
+ args.openFlags = hfile_oflags(mode);
+ if (args.openFlags & O_CREAT) {
+ args.createMode = 0666;
+ addKeyVal(&args.condInput, DEST_RESC_NAME_KW,irods.env.rodsDefResource);
+ }
+
+ ret = rcDataObjOpen(irods.conn, &args);
+ if (ret < 0) goto error;
+ fp->descriptor = ret;
+
+ fp->base.backend = &irods_backend;
+ return &fp->base;
+
+error:
+ hfile_destroy((hFILE *) fp);
+ set_errno(ret);
+ return NULL;
+}
+
+int PLUGIN_GLOBAL(hfile_plugin_init,_irods)(struct hFILE_plugin *self)
+{
+ static const struct hFILE_scheme_handler handler =
+ { hopen_irods, hfile_always_remote, "iRODS", 50 };
+
+ self->name = "iRODS";
+ hfile_add_scheme_handler("irods", &handler);
+ self->destroy = irods_exit;
+ return 0;
+}
--- /dev/null
+/* hfile_libcurl.c -- libcurl backend for low-level file streams.
+
+ Copyright (C) 2015 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <ctype.h>
+#include <stdarg.h>
+#include <stdio.h>
+#include <stdlib.h>
+#include <string.h>
+#include <time.h>
+#include <errno.h>
+#include <sys/select.h>
+
+#include "hfile_internal.h"
+#include "htslib/hts.h" // for hts_version() and hts_verbose
+#include "htslib/kstring.h"
+
+#include <curl/curl.h>
+
+typedef struct {
+ hFILE base;
+ CURL *easy;
+ struct curl_slist *headers;
+ off_t file_size;
+ struct {
+ union { char *rd; const char *wr; } ptr;
+ size_t len;
+ } buffer;
+ CURLcode final_result; // easy result code for finished transfers
+ // Flags for communicating with libcurl callbacks:
+ unsigned paused : 1; // callback tells us that it has paused transfer
+ unsigned closing : 1; // informs callback that hclose() has been invoked
+ unsigned finished : 1; // wait_perform() tells us transfer is complete
+} hFILE_libcurl;
+
+static int http_status_errno(int status)
+{
+ if (status >= 500)
+ switch (status) {
+ case 501: return ENOSYS;
+ case 503: return EBUSY;
+ case 504: return ETIMEDOUT;
+ default: return EIO;
+ }
+ else if (status >= 400)
+ switch (status) {
+ case 401: return EPERM;
+ case 403: return EACCES;
+ case 404: return ENOENT;
+ case 405: return EROFS;
+ case 407: return EPERM;
+ case 408: return ETIMEDOUT;
+ case 410: return ENOENT;
+ default: return EINVAL;
+ }
+ else return 0;
+}
+
+static int easy_errno(CURL *easy, CURLcode err)
+{
+ long lval;
+
+ switch (err) {
+ case CURLE_OK:
+ return 0;
+
+ case CURLE_UNSUPPORTED_PROTOCOL:
+ case CURLE_URL_MALFORMAT:
+ return EINVAL;
+
+#if LIBCURL_VERSION_NUM >= 0x071505
+ case CURLE_NOT_BUILT_IN:
+ return ENOSYS;
+#endif
+
+ case CURLE_COULDNT_RESOLVE_PROXY:
+ case CURLE_COULDNT_RESOLVE_HOST:
+ case CURLE_FTP_CANT_GET_HOST:
+ return EDESTADDRREQ; // Lookup failure
+
+ case CURLE_COULDNT_CONNECT:
+ case CURLE_SEND_ERROR:
+ case CURLE_RECV_ERROR:
+ if (curl_easy_getinfo(easy, CURLINFO_OS_ERRNO, &lval) == CURLE_OK)
+ return lval;
+ else
+ return ECONNABORTED;
+
+ case CURLE_REMOTE_ACCESS_DENIED:
+ case CURLE_LOGIN_DENIED:
+ case CURLE_TFTP_PERM:
+ return EACCES;
+
+ case CURLE_PARTIAL_FILE:
+ return EPIPE;
+
+ case CURLE_HTTP_RETURNED_ERROR:
+ if (curl_easy_getinfo(easy, CURLINFO_RESPONSE_CODE, &lval) == CURLE_OK)
+ return http_status_errno(lval);
+ else
+ return EIO;
+
+ case CURLE_OUT_OF_MEMORY:
+ return ENOMEM;
+
+ case CURLE_OPERATION_TIMEDOUT:
+ return ETIMEDOUT;
+
+ case CURLE_RANGE_ERROR:
+ return ESPIPE;
+
+ case CURLE_SSL_CONNECT_ERROR:
+ // TODO return SSL error buffer messages
+ return ECONNABORTED;
+
+ case CURLE_FILE_COULDNT_READ_FILE:
+ case CURLE_TFTP_NOTFOUND:
+ return ENOENT;
+
+ case CURLE_TOO_MANY_REDIRECTS:
+ return ELOOP;
+
+ case CURLE_FILESIZE_EXCEEDED:
+ return EFBIG;
+
+ case CURLE_REMOTE_DISK_FULL:
+ return ENOSPC;
+
+ case CURLE_REMOTE_FILE_EXISTS:
+ return EEXIST;
+
+ default:
+ return EIO;
+ }
+}
+
+static int multi_errno(CURLMcode errm)
+{
+ switch (errm) {
+ case CURLM_CALL_MULTI_PERFORM:
+ case CURLM_OK:
+ return 0;
+
+ case CURLM_BAD_HANDLE:
+ case CURLM_BAD_EASY_HANDLE:
+ case CURLM_BAD_SOCKET:
+ return EBADF;
+
+ case CURLM_OUT_OF_MEMORY:
+ return ENOMEM;
+
+ default:
+ return EIO;
+ }
+}
+
+
+static struct {
+ CURLM *multi;
+ kstring_t useragent;
+ int nrunning;
+ unsigned perform_again : 1;
+} curl = { NULL, { 0, 0, NULL }, 0, 0 };
+
+static void libcurl_exit()
+{
+ (void) curl_multi_cleanup(curl.multi);
+ curl.multi = NULL;
+
+ free(curl.useragent.s);
+ curl.useragent.l = curl.useragent.m = 0; curl.useragent.s = NULL;
+
+ curl_global_cleanup();
+}
+
+
+static void process_messages()
+{
+ CURLMsg *msg;
+ int remaining;
+
+ while ((msg = curl_multi_info_read(curl.multi, &remaining)) != NULL) {
+ hFILE_libcurl *fp = NULL;
+ curl_easy_getinfo(msg->easy_handle, CURLINFO_PRIVATE, (char **) &fp);
+ switch (msg->msg) {
+ case CURLMSG_DONE:
+ fp->finished = 1;
+ fp->final_result = msg->data.result;
+ break;
+
+ default:
+ break;
+ }
+ }
+}
+
+static int wait_perform()
+{
+ fd_set rd, wr, ex;
+ int maxfd, nrunning;
+ long timeout;
+ CURLMcode errm;
+
+ FD_ZERO(&rd);
+ FD_ZERO(&wr);
+ FD_ZERO(&ex);
+ if (curl_multi_fdset(curl.multi, &rd, &wr, &ex, &maxfd) != CURLM_OK)
+ maxfd = -1, timeout = 1000;
+ else if (maxfd < 0)
+ timeout = 100; // as recommended by curl_multi_fdset(3)
+ else {
+ if (curl_multi_timeout(curl.multi, &timeout) != CURLM_OK)
+ timeout = 1000;
+ else if (timeout < 0)
+ timeout = 10000; // as recommended by curl_multi_timeout(3)
+ }
+
+ if (timeout > 0 && ! curl.perform_again) {
+ struct timeval tval;
+ tval.tv_sec = (timeout / 1000);
+ tval.tv_usec = (timeout % 1000) * 1000;
+
+ if (select(maxfd + 1, &rd, &wr, &ex, &tval) < 0) return -1;
+ }
+
+ errm = curl_multi_perform(curl.multi, &nrunning);
+ curl.perform_again = 0;
+ if (errm == CURLM_CALL_MULTI_PERFORM) curl.perform_again = 1;
+ else if (errm != CURLM_OK) { errno = multi_errno(errm); return -1; }
+
+ if (nrunning < curl.nrunning) process_messages();
+ return 0;
+}
+
+
+static size_t recv_callback(char *ptr, size_t size, size_t nmemb, void *fpv)
+{
+ hFILE_libcurl *fp = (hFILE_libcurl *) fpv;
+ size_t n = size * nmemb;
+
+ if (n > fp->buffer.len) { fp->paused = 1; return CURL_WRITEFUNC_PAUSE; }
+ else if (n == 0) return 0;
+
+ memcpy(fp->buffer.ptr.rd, ptr, n);
+ fp->buffer.ptr.rd += n;
+ fp->buffer.len -= n;
+ return n;
+}
+
+static ssize_t libcurl_read(hFILE *fpv, void *bufferv, size_t nbytes)
+{
+ hFILE_libcurl *fp = (hFILE_libcurl *) fpv;
+ char *buffer = (char *) bufferv;
+ CURLcode err;
+
+ fp->buffer.ptr.rd = buffer;
+ fp->buffer.len = nbytes;
+ fp->paused = 0;
+ err = curl_easy_pause(fp->easy, CURLPAUSE_CONT);
+ if (err != CURLE_OK) { errno = easy_errno(fp->easy, err); return -1; }
+
+ while (! fp->paused && ! fp->finished)
+ if (wait_perform() < 0) return -1;
+
+ nbytes = fp->buffer.ptr.rd - buffer;
+ fp->buffer.ptr.rd = NULL;
+ fp->buffer.len = 0;
+
+ if (fp->finished && fp->final_result != CURLE_OK) {
+ errno = easy_errno(fp->easy, fp->final_result);
+ return -1;
+ }
+
+ return nbytes;
+}
+
+static size_t send_callback(char *ptr, size_t size, size_t nmemb, void *fpv)
+{
+ hFILE_libcurl *fp = (hFILE_libcurl *) fpv;
+ size_t n = size * nmemb;
+
+ if (fp->buffer.len == 0) {
+ // Send buffer is empty; normally pause, or signal EOF if we're closing
+ if (fp->closing) return 0;
+ else { fp->paused = 1; return CURL_READFUNC_PAUSE; }
+ }
+
+ if (n > fp->buffer.len) n = fp->buffer.len;
+ memcpy(ptr, fp->buffer.ptr.wr, n);
+ fp->buffer.ptr.wr += n;
+ fp->buffer.len -= n;
+ return n;
+}
+
+static ssize_t libcurl_write(hFILE *fpv, const void *bufferv, size_t nbytes)
+{
+ hFILE_libcurl *fp = (hFILE_libcurl *) fpv;
+ const char *buffer = (const char *) bufferv;
+ CURLcode err;
+
+ fp->buffer.ptr.wr = buffer;
+ fp->buffer.len = nbytes;
+ fp->paused = 0;
+ err = curl_easy_pause(fp->easy, CURLPAUSE_CONT);
+ if (err != CURLE_OK) { errno = easy_errno(fp->easy, err); return -1; }
+
+ while (! fp->paused && ! fp->finished)
+ if (wait_perform() < 0) return -1;
+
+ nbytes = fp->buffer.ptr.wr - buffer;
+ fp->buffer.ptr.wr = NULL;
+ fp->buffer.len = 0;
+
+ if (fp->finished && fp->final_result != CURLE_OK) {
+ errno = easy_errno(fp->easy, fp->final_result);
+ return -1;
+ }
+
+ return nbytes;
+}
+
+static off_t libcurl_seek(hFILE *fpv, off_t offset, int whence)
+{
+ hFILE_libcurl *fp = (hFILE_libcurl *) fpv;
+
+ CURLcode err;
+ CURLMcode errm;
+ off_t origin, pos;
+
+ switch (whence) {
+ case SEEK_SET:
+ origin = 0;
+ break;
+ case SEEK_CUR:
+ errno = ENOSYS;
+ return -1;
+ case SEEK_END:
+ if (fp->file_size < 0) { errno = ESPIPE; return -1; }
+ origin = fp->file_size;
+ break;
+ default:
+ errno = EINVAL;
+ return -1;
+ }
+
+ // Check 0 <= origin+offset < fp->file_size carefully, avoiding overflow
+ if ((offset < 0)? origin + offset < 0
+ : (fp->file_size >= 0 && offset > fp->file_size - origin)) {
+ errno = EINVAL;
+ return -1;
+ }
+
+ pos = origin + offset;
+
+ errm = curl_multi_remove_handle(curl.multi, fp->easy);
+ if (errm != CURLM_OK) { errno = multi_errno(errm); return -1; }
+ curl.nrunning--;
+
+ // TODO If we seem to be doing random access, use CURLOPT_RANGE to do
+ // limited reads (e.g. about a BAM block!) so seeking can reuse the
+ // existing connection more often.
+
+ if (pos <= 2147483647) err = curl_easy_setopt(fp->easy, CURLOPT_RESUME_FROM, (long) pos);
+ else err = curl_easy_setopt(fp->easy, CURLOPT_RESUME_FROM_LARGE, (curl_off_t) pos);
+ if (err != CURLE_OK) { errno = easy_errno(fp->easy, err); return -1; }
+
+ fp->buffer.len = 0;
+ fp->paused = fp->finished = 0;
+
+ errm = curl_multi_add_handle(curl.multi, fp->easy);
+ if (errm != CURLM_OK) { errno = multi_errno(errm); return -1; }
+ curl.nrunning++;
+
+ err = curl_easy_pause(fp->easy, CURLPAUSE_CONT);
+ if (err != CURLE_OK) { errno = easy_errno(fp->easy, err); return -1; }
+
+ while (! fp->paused && ! fp->finished)
+ if (wait_perform() < 0) return -1;
+
+ if (fp->finished && fp->final_result != CURLE_OK) {
+ errno = easy_errno(fp->easy, fp->final_result);
+ return -1;
+ }
+
+ return pos;
+}
+
+static int libcurl_close(hFILE *fpv)
+{
+ hFILE_libcurl *fp = (hFILE_libcurl *) fpv;
+ CURLcode err;
+ CURLMcode errm;
+ int save_errno = 0;
+
+ // Before closing the file, unpause it and perform on it so that uploads
+ // have the opportunity to signal EOF to the server -- see send_callback().
+
+ fp->buffer.len = 0;
+ fp->closing = 1;
+ fp->paused = 0;
+ err = curl_easy_pause(fp->easy, CURLPAUSE_CONT);
+ if (err != CURLE_OK) save_errno = easy_errno(fp->easy, err);
+
+ while (save_errno == 0 && ! fp->paused && ! fp->finished)
+ if (wait_perform() < 0) save_errno = errno;
+
+ if (fp->finished && fp->final_result != CURLE_OK)
+ save_errno = easy_errno(fp->easy, fp->final_result);
+
+ errm = curl_multi_remove_handle(curl.multi, fp->easy);
+ if (errm != CURLM_OK && save_errno == 0) save_errno = multi_errno(errm);
+ curl.nrunning--;
+
+ curl_easy_cleanup(fp->easy);
+
+ if (save_errno) { errno = save_errno; return -1; }
+ else return 0;
+}
+
+static const struct hFILE_backend libcurl_backend =
+{
+ libcurl_read, libcurl_write, libcurl_seek, NULL, libcurl_close
+};
+
+static int add_header(hFILE_libcurl *fp, const char *header)
+{
+ struct curl_slist *list = curl_slist_append(fp->headers, header);
+ if (list == NULL) { errno = ENOMEM; return -1; }
+ fp->headers = list;
+ return 0;
+}
+
+static int
+add_s3_settings(hFILE_libcurl *fp, const char *url, kstring_t *message);
+
+hFILE *hopen_libcurl(const char *url, const char *modes)
+{
+ hFILE_libcurl *fp;
+ char mode;
+ const char *s;
+ CURLcode err;
+ CURLMcode errm;
+ int save;
+
+ if ((s = strpbrk(modes, "rwa+")) != NULL) {
+ mode = *s;
+ if (strpbrk(&s[1], "rwa+")) mode = 'e';
+ }
+ else mode = '\0';
+
+ if (mode != 'r' && mode != 'w') { errno = EINVAL; return NULL; }
+
+ fp = (hFILE_libcurl *) hfile_init(sizeof (hFILE_libcurl), modes, 0);
+ if (fp == NULL) return NULL;
+
+ fp->easy = curl_easy_init();
+ if (fp->easy == NULL) { errno = ENOMEM; goto error; }
+
+ fp->headers = NULL;
+ fp->file_size = -1;
+ fp->buffer.ptr.rd = NULL;
+ fp->buffer.len = 0;
+ fp->final_result = (CURLcode) -1;
+ fp->paused = fp->closing = fp->finished = 0;
+
+ // Make a route to the hFILE_libcurl* given just a CURL* easy handle
+ err = curl_easy_setopt(fp->easy, CURLOPT_PRIVATE, fp);
+
+ if (mode == 'r') {
+ err |= curl_easy_setopt(fp->easy, CURLOPT_WRITEFUNCTION, recv_callback);
+ err |= curl_easy_setopt(fp->easy, CURLOPT_WRITEDATA, fp);
+ }
+ else {
+ err |= curl_easy_setopt(fp->easy, CURLOPT_READFUNCTION, send_callback);
+ err |= curl_easy_setopt(fp->easy, CURLOPT_READDATA, fp);
+ err |= curl_easy_setopt(fp->easy, CURLOPT_UPLOAD, 1L);
+ if (add_header(fp, "Transfer-Encoding: chunked") < 0) goto error;
+ }
+
+ if (tolower(url[0]) == 's' && url[1] == '3') {
+ // Construct the HTTP-Method/Content-MD5/Content-Type part of the
+ // message to be signed. This will be destroyed by add_s3_settings().
+ kstring_t message = { 0, 0, NULL };
+ kputs((mode == 'r')? "GET\n" : "PUT\n", &message);
+ kputc('\n', &message);
+ kputc('\n', &message);
+ if (add_s3_settings(fp, url, &message) < 0) goto error;
+ }
+ else
+ err |= curl_easy_setopt(fp->easy, CURLOPT_URL, url);
+
+ err |= curl_easy_setopt(fp->easy, CURLOPT_USERAGENT, curl.useragent.s);
+ if (fp->headers)
+ err |= curl_easy_setopt(fp->easy, CURLOPT_HTTPHEADER, fp->headers);
+ err |= curl_easy_setopt(fp->easy, CURLOPT_FOLLOWLOCATION, 1L);
+ err |= curl_easy_setopt(fp->easy, CURLOPT_FAILONERROR, 1L);
+ if (hts_verbose >= 8)
+ err |= curl_easy_setopt(fp->easy, CURLOPT_VERBOSE, 1L);
+
+ if (err != 0) { errno = ENOSYS; goto error; }
+
+ errm = curl_multi_add_handle(curl.multi, fp->easy);
+ if (errm != CURLM_OK) { errno = multi_errno(errm); goto error; }
+ curl.nrunning++;
+
+ while (! fp->paused && ! fp->finished)
+ if (wait_perform() < 0) goto error_remove;
+
+ if (fp->finished && fp->final_result != CURLE_OK) {
+ errno = easy_errno(fp->easy, fp->final_result);
+ goto error_remove;
+ }
+
+ if (mode == 'r') {
+ double dval;
+ if (curl_easy_getinfo(fp->easy, CURLINFO_CONTENT_LENGTH_DOWNLOAD,
+ &dval) == CURLE_OK && dval >= 0.0)
+ fp->file_size = (off_t) (dval + 0.1);
+ }
+
+ fp->base.backend = &libcurl_backend;
+ return &fp->base;
+
+error_remove:
+ save = errno;
+ (void) curl_multi_remove_handle(curl.multi, fp->easy);
+ curl.nrunning--;
+ errno = save;
+
+error:
+ save = errno;
+ curl_easy_cleanup(fp->easy);
+ if (fp->headers) curl_slist_free_all(fp->headers);
+ hfile_destroy((hFILE *) fp);
+ errno = save;
+ return NULL;
+}
+
+int PLUGIN_GLOBAL(hfile_plugin_init,_libcurl)(struct hFILE_plugin *self)
+{
+ static const struct hFILE_scheme_handler handler =
+ { hopen_libcurl, hfile_always_remote, "libcurl", 50 };
+
+ const curl_version_info_data *info;
+ const char * const *protocol;
+ CURLcode err;
+
+ err = curl_global_init(CURL_GLOBAL_ALL);
+ if (err != CURLE_OK) { errno = easy_errno(NULL, err); return -1; }
+
+ curl.multi = curl_multi_init();
+ if (curl.multi == NULL) { curl_global_cleanup(); errno = EIO; return -1; }
+
+ info = curl_version_info(CURLVERSION_NOW);
+ ksprintf(&curl.useragent, "htslib/%s libcurl/%s",
+ hts_version(), info->version);
+
+ curl.nrunning = 0;
+ curl.perform_again = 0;
+ self->name = "libcurl";
+ self->destroy = libcurl_exit;
+
+ for (protocol = info->protocols; *protocol; protocol++)
+ hfile_add_scheme_handler(*protocol, &handler);
+
+ hfile_add_scheme_handler("s3", &handler);
+ hfile_add_scheme_handler("s3+http", &handler);
+ if (info->features & CURL_VERSION_SSL)
+ hfile_add_scheme_handler("s3+https", &handler);
+
+ return 0;
+}
+
+
+/*******************
+ * Rewrite S3 URLs *
+ *******************/
+
+#if defined HAVE_COMMONCRYPTO
+
+#include <CommonCrypto/CommonHMAC.h>
+
+#define DIGEST_BUFSIZ CC_SHA1_DIGEST_LENGTH
+
+static size_t
+s3_sign(unsigned char *digest, kstring_t *key, kstring_t *message)
+{
+ CCHmac(kCCHmacAlgSHA1, key->s, key->l, message->s, message->l, digest);
+ return CC_SHA1_DIGEST_LENGTH;
+}
+
+#elif defined HAVE_HMAC
+
+#include <openssl/hmac.h>
+
+#define DIGEST_BUFSIZ EVP_MAX_MD_SIZE
+
+static size_t
+s3_sign(unsigned char *digest, kstring_t *key, kstring_t *message)
+{
+ unsigned int len;
+ HMAC(EVP_sha1(), key->s, key->l,
+ (unsigned char *) message->s, message->l, digest, &len);
+ return len;
+}
+
+#else
+#error No HMAC() routine found by configure
+#endif
+
+static void
+urldecode_kput(const char *s, int len, hFILE_libcurl *fp, kstring_t *str)
+{
+ if (memchr(s, '%', len) != NULL) {
+ int len2;
+ char *s2 = curl_easy_unescape(fp->easy, s, len, &len2);
+ if (s2 == NULL) abort();
+ kputsn(s2, len2, str);
+ curl_free(s2);
+ }
+ else kputsn(s, len, str);
+}
+
+static void base64_kput(const unsigned char *data, size_t len, kstring_t *str)
+{
+ static const char base64[] =
+ "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/";
+
+ size_t i = 0;
+ unsigned x = 0;
+ int bits = 0, pad = 0;
+
+ while (bits || i < len) {
+ if (bits < 6) {
+ x <<= 8, bits += 8;
+ if (i < len) x |= data[i++];
+ else pad++;
+ }
+
+ bits -= 6;
+ kputc(base64[(x >> bits) & 63], str);
+ }
+
+ str->l -= pad;
+ kputsn("==", pad, str);
+}
+
+static int is_dns_compliant(const char *s0, const char *slim)
+{
+ int has_nondigit = 0, len = 0;
+ const char *s;
+
+ for (s = s0; s < slim; len++, s++)
+ if (islower(*s))
+ has_nondigit = 1;
+ else if (*s == '-') {
+ has_nondigit = 1;
+ if (s == s0 || s+1 == slim) return 0;
+ }
+ else if (isdigit(*s))
+ ;
+ else if (*s == '.') {
+ if (s == s0 || ! isalnum(s[-1])) return 0;
+ if (s+1 == slim || ! isalnum(s[1])) return 0;
+ }
+ else return 0;
+
+ return has_nondigit && len >= 3 && len <= 63;
+}
+
+static FILE *expand_tilde_open(const char *fname, const char *mode)
+{
+ FILE *fp;
+
+ if (strncmp(fname, "~/", 2) == 0) {
+ kstring_t full_fname = { 0, 0, NULL };
+ const char *home = getenv("HOME");
+ if (! home) return NULL;
+
+ kputs(home, &full_fname);
+ kputs(&fname[1], &full_fname);
+
+ fp = fopen(full_fname.s, mode);
+ free(full_fname.s);
+ }
+ else
+ fp = fopen(fname, mode);
+
+ return fp;
+}
+
+static void parse_ini(const char *fname, const char *section, ...)
+{
+ kstring_t line = { 0, 0, NULL };
+ int active = 1; // Start active, so global properties are accepted
+ char *s;
+
+ FILE *fp = expand_tilde_open(fname, "r");
+ if (fp == NULL) return;
+
+ while (line.l = 0, kgetline(&line, (kgets_func *) fgets, fp) >= 0)
+ if (line.s[0] == '[' && (s = strchr(line.s, ']')) != NULL) {
+ *s = '\0';
+ active = (strcmp(&line.s[1], section) == 0);
+ }
+ else if (active && (s = strpbrk(line.s, ":=")) != NULL) {
+ const char *key = line.s, *value = &s[1], *akey;
+ va_list args;
+
+ while (isspace(*key)) key++;
+ while (s > key && isspace(s[-1])) s--;
+ *s = '\0';
+
+ while (isspace(*value)) value++;
+ while (line.l > 0 && isspace(line.s[line.l-1]))
+ line.s[--line.l] = '\0';
+
+ va_start(args, section);
+ while ((akey = va_arg(args, const char *)) != NULL) {
+ kstring_t *avar = va_arg(args, kstring_t *);
+ if (strcmp(key, akey) == 0) { kputs(value, avar); break; }
+ }
+ va_end(args);
+ }
+
+ fclose(fp);
+ free(line.s);
+}
+
+static void parse_simple(const char *fname, kstring_t *id, kstring_t *secret)
+{
+ kstring_t text = { 0, 0, NULL };
+ char *s;
+ size_t len;
+
+ FILE *fp = expand_tilde_open(fname, "r");
+ if (fp == NULL) return;
+
+ while (kgetline(&text, (kgets_func *) fgets, fp) >= 0)
+ kputc(' ', &text);
+ fclose(fp);
+
+ s = text.s;
+ while (isspace(*s)) s++;
+ kputsn(s, len = strcspn(s, " \t"), id);
+
+ s += len;
+ while (isspace(*s)) s++;
+ kputsn(s, strcspn(s, " \t"), secret);
+
+ free(text.s);
+}
+
+static int
+add_s3_settings(hFILE_libcurl *fp, const char *s3url, kstring_t *message)
+{
+ int ret, save;
+ const char *bucket, *path;
+ char date_hdr[40];
+ CURLcode err;
+
+ kstring_t url = { 0, 0, NULL };
+ kstring_t profile = { 0, 0, NULL };
+ kstring_t id = { 0, 0, NULL };
+ kstring_t secret = { 0, 0, NULL };
+ kstring_t token = { 0, 0, NULL };
+ kstring_t token_hdr = { 0, 0, NULL };
+ kstring_t auth_hdr = { 0, 0, NULL };
+
+ time_t now = time(NULL);
+#ifdef HAVE_GMTIME_R
+ struct tm tm_buffer;
+ struct tm *tm = gmtime_r(&now, &tm_buffer);
+#else
+ struct tm *tm = gmtime(&now);
+#endif
+
+ strftime(date_hdr, sizeof date_hdr, "Date: %a, %d %b %Y %H:%M:%S GMT", tm);
+ if (add_header(fp, date_hdr) < 0) goto error;
+ kputs(&date_hdr[6], message);
+ kputc('\n', message);
+
+ // Our S3 URL format is s3[+SCHEME]://[ID[:SECRET[:TOKEN]]@]BUCKET/PATH
+
+ if (s3url[2] == '+') {
+ bucket = strchr(s3url, ':') + 1;
+ kputsn(&s3url[3], bucket - &s3url[3], &url);
+ }
+ else {
+ kputs("https:", &url);
+ bucket = &s3url[3];
+ }
+ while (*bucket == '/') kputc(*bucket++, &url);
+
+ path = bucket + strcspn(bucket, "/?#@");
+ if (*path == '@') {
+ const char *colon = strpbrk(bucket, ":@");
+ if (*colon != ':') {
+ urldecode_kput(bucket, colon - bucket, fp, &profile);
+ }
+ else {
+ const char *colon2 = strpbrk(&colon[1], ":@");
+ urldecode_kput(bucket, colon - bucket, fp, &id);
+ urldecode_kput(&colon[1], colon2 - &colon[1], fp, &secret);
+ if (*colon2 == ':')
+ urldecode_kput(&colon2[1], path - &colon2[1], fp, &token);
+ }
+
+ bucket = &path[1];
+ path = bucket + strcspn(bucket, "/?#");
+ }
+ else {
+ // If the URL has no ID[:SECRET]@, consider environment variables.
+ const char *v;
+ if ((v = getenv("AWS_ACCESS_KEY_ID")) != NULL) kputs(v, &id);
+ if ((v = getenv("AWS_SECRET_ACCESS_KEY")) != NULL) kputs(v, &secret);
+ if ((v = getenv("AWS_SESSION_TOKEN")) != NULL) kputs(v, &token);
+
+ if ((v = getenv("AWS_DEFAULT_PROFILE")) != NULL) kputs(v, &profile);
+ else if ((v = getenv("AWS_PROFILE")) != NULL) kputs(v, &profile);
+ else kputs("default", &profile);
+ }
+
+ // Use virtual hosted-style access if possible, otherwise path-style.
+ if (is_dns_compliant(bucket, path)) {
+ kputsn(bucket, path - bucket, &url);
+ kputs(".s3.amazonaws.com", &url);
+ }
+ else {
+ kputs("s3.amazonaws.com/", &url);
+ kputsn(bucket, path - bucket, &url);
+ }
+ kputs(path, &url);
+
+ if (id.l == 0) {
+ const char *v = getenv("AWS_SHARED_CREDENTIALS_FILE");
+ parse_ini(v? v : "~/.aws/credentials", profile.s,
+ "aws_access_key_id", &id, "aws_secret_access_key", &secret,
+ "aws_session_token", &token, NULL);
+ }
+ if (id.l == 0)
+ parse_ini("~/.s3cfg", profile.s, "access_key", &id,
+ "secret_key", &secret, "access_token", &token, NULL);
+ if (id.l == 0)
+ parse_simple("~/.awssecret", &id, &secret);
+
+ if (token.l > 0) {
+ kputs("x-amz-security-token:", message);
+ kputs(token.s, message);
+ kputc('\n', message);
+
+ kputs("X-Amz-Security-Token: ", &token_hdr);
+ kputs(token.s, &token_hdr);
+ if (add_header(fp, token_hdr.s) < 0) goto error;
+ }
+
+ kputc('/', message);
+ kputs(bucket, message); // CanonicalizedResource is '/' + bucket + path
+
+ err = curl_easy_setopt(fp->easy, CURLOPT_URL, url.s);
+ if (err != CURLE_OK) { errno = easy_errno(fp->easy, err); goto error; }
+
+ // If we have no id/secret, we can't sign the request but will
+ // still be able to access public data sets.
+ if (id.l > 0 && secret.l > 0) {
+ unsigned char digest[DIGEST_BUFSIZ];
+ size_t digest_len = s3_sign(digest, &secret, message);
+
+ kputs("Authorization: AWS ", &auth_hdr);
+ kputs(id.s, &auth_hdr);
+ kputc(':', &auth_hdr);
+ base64_kput(digest, digest_len, &auth_hdr);
+
+ if (add_header(fp, auth_hdr.s) < 0) goto error;
+ }
+
+ ret = 0;
+ goto free_and_return;
+
+error:
+ ret = -1;
+
+free_and_return:
+ save = errno;
+ free(url.s);
+ free(profile.s);
+ free(id.s);
+ free(secret.s);
+ free(token.s);
+ free(token_hdr.s);
+ free(auth_hdr.s);
+ free(message->s);
+ errno = save;
+ return ret;
+}
--- /dev/null
+/* hfile_net.c -- network backend for low-level input/output streams.
+
+ Copyright (C) 2013-2015 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdlib.h>
+#include <errno.h>
+
+#include "hfile_internal.h"
+
+#include "htslib/knetfile.h"
+
+typedef struct {
+ hFILE base;
+ knetFile *netfp;
+} hFILE_net;
+
+static int net_inited = 0;
+
+#ifdef _WIN32
+static void net_exit(void)
+{
+ knet_win32_destroy();
+}
+#endif
+
+static int net_init(void)
+{
+#ifdef _WIN32
+ if (knet_win32_init() != 0) return -1;
+
+ // In the unlikely event atexit() fails, it's better to succeed here and
+ // carry on and do the I/O; then eventually when the program exits, we'll
+ // merely have failed to clean up properly, as if we had aborted.
+ (void) atexit(net_exit);
+#endif
+
+ net_inited = 1;
+ return 0;
+}
+
+static ssize_t net_read(hFILE *fpv, void *buffer, size_t nbytes)
+{
+ hFILE_net *fp = (hFILE_net *) fpv;
+ return knet_read(fp->netfp, buffer, nbytes);
+}
+
+static off_t net_seek(hFILE *fpv, off_t offset, int whence)
+{
+ hFILE_net *fp = (hFILE_net *) fpv;
+ return knet_seek(fp->netfp, offset, whence);
+}
+
+static int net_close(hFILE *fpv)
+{
+ hFILE_net *fp = (hFILE_net *) fpv;
+ return knet_close(fp->netfp);
+}
+
+static const struct hFILE_backend net_backend =
+{
+ net_read, NULL, net_seek, NULL, net_close
+};
+
+hFILE *hopen_net(const char *filename, const char *mode)
+{
+ hFILE_net *fp;
+
+ // Do any networking initialisation if this is the first use.
+ if (! net_inited) { if (net_init() < 0) return NULL; }
+
+ fp = (hFILE_net *) hfile_init(sizeof (hFILE_net), mode, 0);
+ if (fp == NULL) return NULL;
+
+ fp->netfp = knet_open(filename, mode);
+ if (fp->netfp == NULL) { hfile_destroy((hFILE *) fp); return NULL; }
+
+ fp->base.backend = &net_backend;
+ return &fp->base;
+}
+
+int hfile_plugin_init_net(struct hFILE_plugin *self)
+{
+ static const struct hFILE_scheme_handler handler =
+ { hopen_net, hfile_always_remote, "knetfile", 0 };
+
+ self->name = "knetfile";
+ hfile_add_scheme_handler("http", &handler);
+ hfile_add_scheme_handler("ftp", &handler);
+ return 0;
+}
--- /dev/null
+/* hts.c -- format-neutral I/O, indexing, and iterator API functions.
+
+ Copyright (C) 2008, 2009, 2012-2016 Genome Research Ltd.
+ Copyright (C) 2012, 2013 Broad Institute.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <zlib.h>
+#include <ctype.h>
+#include <stdio.h>
+#include <string.h>
+#include <stdlib.h>
+#include <limits.h>
+#include <fcntl.h>
+#include <errno.h>
+#include <sys/stat.h>
+#include "htslib/bgzf.h"
+#include "htslib/hts.h"
+#include "cram/cram.h"
+#include "htslib/hfile.h"
+#include "version.h"
+#include "hts_internal.h"
+
+#include "htslib/kseq.h"
+#define KS_BGZF 1
+#if KS_BGZF
+ // bgzf now supports gzip-compressed files, the gzFile branch can be removed
+ KSTREAM_INIT2(, BGZF*, bgzf_read, 65536)
+#else
+ KSTREAM_INIT2(, gzFile, gzread, 16384)
+#endif
+
+#include "htslib/khash.h"
+KHASH_INIT2(s2i,, kh_cstr_t, int64_t, 1, kh_str_hash_func, kh_str_hash_equal)
+
+int hts_verbose = 3;
+
+const char *hts_version()
+{
+ return HTS_VERSION;
+}
+
+const unsigned char seq_nt16_table[256] = {
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 1, 2, 4, 8, 15,15,15,15, 15,15,15,15, 15, 0 /*=*/,15,15,
+ 15, 1,14, 2, 13,15,15, 4, 11,15,15,12, 15, 3,15,15,
+ 15,15, 5, 6, 8,15, 7, 9, 15,10,15,15, 15,15,15,15,
+ 15, 1,14, 2, 13,15,15, 4, 11,15,15,12, 15, 3,15,15,
+ 15,15, 5, 6, 8,15, 7, 9, 15,10,15,15, 15,15,15,15,
+
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15,
+ 15,15,15,15, 15,15,15,15, 15,15,15,15, 15,15,15,15
+};
+
+const char seq_nt16_str[] = "=ACMGRSVTWYHKDBN";
+
+const int seq_nt16_int[] = { 4, 0, 1, 4, 2, 4, 4, 4, 3, 4, 4, 4, 4, 4, 4, 4 };
+
+/**********************
+ *** Basic file I/O ***
+ **********************/
+
+static enum htsFormatCategory format_category(enum htsExactFormat fmt)
+{
+ switch (fmt) {
+ case bam:
+ case sam:
+ case cram:
+ return sequence_data;
+
+ case vcf:
+ case bcf:
+ return variant_data;
+
+ case bai:
+ case crai:
+ case csi:
+ case gzi:
+ case tbi:
+ return index_file;
+
+ case bed:
+ return region_list;
+
+ case unknown_format:
+ case binary_format:
+ case text_format:
+ case format_maximum:
+ break;
+ }
+
+ return unknown_category;
+}
+
+// Decompress up to ten or so bytes by peeking at the file, which must be
+// positioned at the start of a GZIP block.
+static size_t decompress_peek(hFILE *fp, unsigned char *dest, size_t destsize)
+{
+ // Typically at most a couple of hundred bytes of input are required
+ // to get a few bytes of output from inflate(), so hopefully this buffer
+ // size suffices in general.
+ unsigned char buffer[512];
+ z_stream zs;
+ ssize_t npeek = hpeek(fp, buffer, sizeof buffer);
+
+ if (npeek < 0) return 0;
+
+ zs.zalloc = NULL;
+ zs.zfree = NULL;
+ zs.next_in = buffer;
+ zs.avail_in = npeek;
+ zs.next_out = dest;
+ zs.avail_out = destsize;
+ if (inflateInit2(&zs, 31) != Z_OK) return 0;
+
+ while (zs.total_out < destsize)
+ if (inflate(&zs, Z_SYNC_FLUSH) != Z_OK) break;
+
+ destsize = zs.total_out;
+ inflateEnd(&zs);
+
+ return destsize;
+}
+
+// Parse "x.y" text, taking care because the string is not NUL-terminated
+// and filling in major/minor only when the digits are followed by a delimiter,
+// so we don't misread "1.10" as "1.1" due to reaching the end of the buffer.
+static void
+parse_version(htsFormat *fmt, const unsigned char *u, const unsigned char *ulim)
+{
+ const char *s = (const char *) u;
+ const char *slim = (const char *) ulim;
+ short v;
+
+ fmt->version.major = fmt->version.minor = -1;
+
+ for (v = 0; s < slim && isdigit_c(*s); s++)
+ v = 10 * v + *s - '0';
+
+ if (s < slim) {
+ fmt->version.major = v;
+ if (*s == '.') {
+ s++;
+ for (v = 0; s < slim && isdigit_c(*s); s++)
+ v = 10 * v + *s - '0';
+ if (s < slim)
+ fmt->version.minor = v;
+ }
+ else
+ fmt->version.minor = 0;
+ }
+}
+
+int hts_detect_format(hFILE *hfile, htsFormat *fmt)
+{
+ unsigned char s[21];
+ ssize_t len = hpeek(hfile, s, 18);
+ if (len < 0) return -1;
+
+ if (len >= 2 && s[0] == 0x1f && s[1] == 0x8b) {
+ // The stream is either gzip-compressed or BGZF-compressed.
+ // Determine which, and decompress the first few bytes.
+ fmt->compression = (len >= 18 && (s[3] & 4) &&
+ memcmp(&s[12], "BC\2\0", 4) == 0)? bgzf : gzip;
+ len = decompress_peek(hfile, s, sizeof s);
+ }
+ else {
+ fmt->compression = no_compression;
+ len = hpeek(hfile, s, sizeof s);
+ }
+ if (len < 0) return -1;
+
+ fmt->compression_level = -1;
+ fmt->specific = NULL;
+
+ if (len >= 6 && memcmp(s,"CRAM",4) == 0 && s[4]>=1 && s[4]<=3 && s[5]<=1) {
+ fmt->category = sequence_data;
+ fmt->format = cram;
+ fmt->version.major = s[4], fmt->version.minor = s[5];
+ fmt->compression = custom;
+ return 0;
+ }
+ else if (len >= 4 && s[3] <= '\4') {
+ if (memcmp(s, "BAM\1", 4) == 0) {
+ fmt->category = sequence_data;
+ fmt->format = bam;
+ // TODO Decompress enough to pick version from @HD-VN header
+ fmt->version.major = 1, fmt->version.minor = -1;
+ return 0;
+ }
+ else if (memcmp(s, "BAI\1", 4) == 0) {
+ fmt->category = index_file;
+ fmt->format = bai;
+ fmt->version.major = -1, fmt->version.minor = -1;
+ return 0;
+ }
+ else if (memcmp(s, "BCF\4", 4) == 0) {
+ fmt->category = variant_data;
+ fmt->format = bcf;
+ fmt->version.major = 1, fmt->version.minor = -1;
+ return 0;
+ }
+ else if (memcmp(s, "BCF\2", 4) == 0) {
+ fmt->category = variant_data;
+ fmt->format = bcf;
+ fmt->version.major = s[3];
+ fmt->version.minor = (len >= 5 && s[4] <= 2)? s[4] : 0;
+ return 0;
+ }
+ else if (memcmp(s, "CSI\1", 4) == 0) {
+ fmt->category = index_file;
+ fmt->format = csi;
+ fmt->version.major = 1, fmt->version.minor = -1;
+ return 0;
+ }
+ else if (memcmp(s, "TBI\1", 4) == 0) {
+ fmt->category = index_file;
+ fmt->format = tbi;
+ fmt->version.major = -1, fmt->version.minor = -1;
+ return 0;
+ }
+ }
+ else if (len >= 16 && memcmp(s, "##fileformat=VCF", 16) == 0) {
+ fmt->category = variant_data;
+ fmt->format = vcf;
+ if (len >= 21 && s[16] == 'v')
+ parse_version(fmt, &s[17], &s[len]);
+ else
+ fmt->version.major = fmt->version.minor = -1;
+ return 0;
+ }
+ else if (len >= 4 && s[0] == '@' &&
+ (memcmp(s, "@HD\t", 4) == 0 || memcmp(s, "@SQ\t", 4) == 0 ||
+ memcmp(s, "@RG\t", 4) == 0 || memcmp(s, "@PG\t", 4) == 0)) {
+ fmt->category = sequence_data;
+ fmt->format = sam;
+ // @HD-VN is not guaranteed to be the first tag, but then @HD is
+ // not guaranteed to be present at all...
+ if (len >= 9 && memcmp(s, "@HD\tVN:", 7) == 0)
+ parse_version(fmt, &s[7], &s[len]);
+ else
+ fmt->version.major = 1, fmt->version.minor = -1;
+ return 0;
+ }
+ else {
+ // Various possibilities for tab-delimited text:
+ // .crai (gzipped tab-delimited six columns: seqid 5*number)
+ // .bed ([3..12] tab-delimited columns)
+ // .bedpe (>= 10 tab-delimited columns)
+ // .sam (tab-delimited >= 11 columns: seqid number seqid...)
+ // FIXME For now, assume it's SAM
+ fmt->category = sequence_data;
+ fmt->format = sam;
+ fmt->version.major = 1, fmt->version.minor = -1;
+ return 0;
+ }
+
+ fmt->category = unknown_category;
+ fmt->format = unknown_format;
+ fmt->version.major = fmt->version.minor = -1;
+ fmt->compression = no_compression;
+ return 0;
+}
+
+char *hts_format_description(const htsFormat *format)
+{
+ kstring_t str = { 0, 0, NULL };
+
+ switch (format->format) {
+ case sam: kputs("SAM", &str); break;
+ case bam: kputs("BAM", &str); break;
+ case cram: kputs("CRAM", &str); break;
+ case vcf: kputs("VCF", &str); break;
+ case bcf:
+ if (format->version.major == 1) kputs("Legacy BCF", &str);
+ else kputs("BCF", &str);
+ break;
+ case bai: kputs("BAI", &str); break;
+ case crai: kputs("CRAI", &str); break;
+ case csi: kputs("CSI", &str); break;
+ case tbi: kputs("Tabix", &str); break;
+ default: kputs("unknown", &str); break;
+ }
+
+ if (format->version.major >= 0) {
+ kputs(" version ", &str);
+ kputw(format->version.major, &str);
+ if (format->version.minor >= 0) {
+ kputc('.', &str);
+ kputw(format->version.minor, &str);
+ }
+ }
+
+ switch (format->compression) {
+ case custom: kputs(" compressed", &str); break;
+ case gzip: kputs(" gzip-compressed", &str); break;
+ case bgzf:
+ switch (format->format) {
+ case bam:
+ case bcf:
+ case csi:
+ case tbi:
+ // These are by definition BGZF, so just use the generic term
+ kputs(" compressed", &str);
+ break;
+ default:
+ kputs(" BGZF-compressed", &str);
+ break;
+ }
+ break;
+ default: break;
+ }
+
+ switch (format->category) {
+ case sequence_data: kputs(" sequence", &str); break;
+ case variant_data: kputs(" variant calling", &str); break;
+ case index_file: kputs(" index", &str); break;
+ case region_list: kputs(" genomic region", &str); break;
+ default: break;
+ }
+
+ if (format->compression == no_compression)
+ switch (format->format) {
+ case sam:
+ case crai:
+ case vcf:
+ case bed:
+ kputs(" text", &str);
+ break;
+
+ default:
+ kputs(" data", &str);
+ break;
+ }
+ else
+ kputs(" data", &str);
+
+ return ks_release(&str);
+}
+
+htsFile *hts_open_format(const char *fn, const char *mode, const htsFormat *fmt)
+{
+ char smode[102], *cp, *cp2, *mode_c;
+ htsFile *fp = NULL;
+ hFILE *hfile;
+ char fmt_code = '\0';
+
+ strncpy(smode, mode, 100);
+ smode[100]=0;
+ if ((cp = strchr(smode, ',')))
+ *cp = '\0';
+
+ // Migrate format code (b or c) to the end of the smode buffer.
+ for (cp2 = cp = smode; *cp; cp++) {
+ if (*cp == 'b')
+ fmt_code = 'b';
+ else if (*cp == 'c')
+ fmt_code = 'c';
+ else
+ *cp2++ = *cp;
+ }
+ mode_c = cp2;
+ *cp2++ = fmt_code;
+ *cp2++ = 0;
+ *cp2++ = 0;
+
+ // Set or reset the format code if opts->format is used
+ if (fmt && fmt->format != unknown_format)
+ *mode_c = "\0g\0\0b\0c\0\0b\0g\0\0"[fmt->format];
+
+ hfile = hopen(fn, smode);
+ if (hfile == NULL) goto error;
+
+ fp = hts_hopen(hfile, fn, smode);
+ if (fp == NULL) goto error;
+
+ if (fmt && fmt->specific)
+ if (hts_opt_apply(fp, fmt->specific) != 0)
+ goto error;
+
+ return fp;
+
+error:
+ if (hts_verbose >= 2)
+ fprintf(stderr, "[E::%s] fail to open file '%s'\n", __func__, fn);
+
+ if (hfile)
+ hclose_abruptly(hfile);
+
+ return NULL;
+}
+
+htsFile *hts_open(const char *fn, const char *mode) {
+ return hts_open_format(fn, mode, NULL);
+}
+
+/*
+ * Splits str into a prefix, delimiter ('\0' or delim), and suffix, writing
+ * the prefix in lowercase into buf and returning a pointer to the suffix.
+ * On return, buf is always NUL-terminated; thus assumes that the "keyword"
+ * prefix should be one of several known values of maximum length buflen-2.
+ * (If delim is not found, returns a pointer to the '\0'.)
+ */
+static const char *
+scan_keyword(const char *str, char delim, char *buf, size_t buflen)
+{
+ size_t i = 0;
+ while (*str && *str != delim) {
+ if (i < buflen-1) buf[i++] = tolower_c(*str);
+ str++;
+ }
+
+ buf[i] = '\0';
+ return *str? str+1 : str;
+}
+
+/*
+ * Parses arg and appends it to the option list.
+ *
+ * Returns 0 on success;
+ * -1 on failure.
+ */
+int hts_opt_add(hts_opt **opts, const char *c_arg) {
+ hts_opt *o, *t;
+ char *val;
+
+ if (!c_arg)
+ return -1;
+
+ if (!(o = malloc(sizeof(*o))))
+ return -1;
+
+ if (!(o->arg = strdup(c_arg))) {
+ free(o);
+ return -1;
+ }
+
+ if (!(val = strchr(o->arg, '=')))
+ val = "1"; // assume boolean
+ else
+ *val++ = '\0';
+
+ if (strcmp(o->arg, "decode_md") == 0 ||
+ strcmp(o->arg, "DECODE_MD") == 0)
+ o->opt = CRAM_OPT_DECODE_MD, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "verbosity") == 0 ||
+ strcmp(o->arg, "VERBOSITY") == 0)
+ o->opt = CRAM_OPT_VERBOSITY, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "seqs_per_slice") == 0 ||
+ strcmp(o->arg, "SEQS_PER_SLICE") == 0)
+ o->opt = CRAM_OPT_SEQS_PER_SLICE, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "slices_per_container") == 0 ||
+ strcmp(o->arg, "SLICES_PER_CONTAINER") == 0)
+ o->opt = CRAM_OPT_SLICES_PER_CONTAINER, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "embed_ref") == 0 ||
+ strcmp(o->arg, "EMBED_REF") == 0)
+ o->opt = CRAM_OPT_EMBED_REF, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "no_ref") == 0 ||
+ strcmp(o->arg, "NO_REF") == 0)
+ o->opt = CRAM_OPT_NO_REF, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "ignore_md5") == 0 ||
+ strcmp(o->arg, "IGNORE_MD5") == 0)
+ o->opt = CRAM_OPT_IGNORE_MD5, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "use_bzip2") == 0 ||
+ strcmp(o->arg, "USE_BZIP2") == 0)
+ o->opt = CRAM_OPT_USE_BZIP2, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "use_rans") == 0 ||
+ strcmp(o->arg, "USE_RANS") == 0)
+ o->opt = CRAM_OPT_USE_RANS, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "use_lzma") == 0 ||
+ strcmp(o->arg, "USE_LZMA") == 0)
+ o->opt = CRAM_OPT_USE_LZMA, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "reference") == 0 ||
+ strcmp(o->arg, "REFERENCE") == 0)
+ o->opt = CRAM_OPT_REFERENCE, o->val.s = val;
+
+ else if (strcmp(o->arg, "version") == 0 ||
+ strcmp(o->arg, "VERSION") == 0)
+ o->opt = CRAM_OPT_VERSION, o->val.s =val;
+
+ else if (strcmp(o->arg, "multi_seq_per_slice") == 0 ||
+ strcmp(o->arg, "MULTI_SEQ_PER_SLICE") == 0)
+ o->opt = CRAM_OPT_MULTI_SEQ_PER_SLICE, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "nthreads") == 0 ||
+ strcmp(o->arg, "NTHREADS") == 0)
+ o->opt = HTS_OPT_NTHREADS, o->val.i = atoi(val);
+
+ else if (strcmp(o->arg, "required_fields") == 0 ||
+ strcmp(o->arg, "REQUIRED_FIELDS") == 0)
+ o->opt = CRAM_OPT_REQUIRED_FIELDS, o->val.i = strtol(val, NULL, 0);
+
+ else {
+ fprintf(stderr, "Unknown option '%s'\n", o->arg);
+ free(o->arg);
+ free(o);
+ return -1;
+ }
+
+ o->next = NULL;
+
+ // Append; assumes small list.
+ if (*opts) {
+ t = *opts;
+ while (t->next)
+ t = t->next;
+ t->next = o;
+ } else {
+ *opts = o;
+ }
+
+ return 0;
+}
+
+/*
+ * Applies an hts_opt option list to a given htsFile.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int hts_opt_apply(htsFile *fp, hts_opt *opts) {
+ hts_opt *last = NULL;
+
+ for (; opts; opts = (last=opts)->next)
+ if (hts_set_opt(fp, opts->opt, opts->val) != 0)
+ return -1;
+
+ return 0;
+}
+
+/*
+ * Frees an hts_opt list.
+ */
+void hts_opt_free(hts_opt *opts) {
+ hts_opt *last = NULL;
+ while (opts) {
+ opts = (last=opts)->next;
+ free(last->arg);
+ free(last);
+ }
+}
+
+
+/*
+ * Tokenise options as (key(=value)?,)*(key(=value)?)?
+ * NB: No provision for ',' appearing in the value!
+ * Add backslashing rules?
+ *
+ * This could be used as part of a general command line option parser or
+ * as a string concatenated onto the file open mode.
+ *
+ * Returns 0 on success
+ * -1 on failure.
+ */
+int hts_parse_opt_list(htsFormat *fmt, const char *str) {
+ while (str && *str) {
+ const char *str_start;
+ int len;
+ char arg[8001];
+
+ while (*str && *str == ',')
+ str++;
+
+ for (str_start = str; *str && *str != ','; str++);
+ len = str - str_start;
+
+ // Produce a nul terminated copy of the option
+ strncpy(arg, str_start, len < 8000 ? len : 8000);
+ arg[len < 8000 ? len : 8000] = '\0';
+
+ if (hts_opt_add((hts_opt **)&fmt->specific, arg) != 0)
+ return -1;
+
+ if (*str)
+ str++;
+ }
+
+ return 0;
+}
+
+/*
+ * Accepts a string file format (sam, bam, cram, vcf, bam) optionally
+ * followed by a comma separated list of key=value options and splits
+ * these up into the fields of htsFormat struct.
+ *
+ * format is assumed to be already initialised, either to blank
+ * "unknown" values or via previous hts_opt_add calls.
+ *
+ * Returns 0 on success
+ * -1 on failure.
+ */
+int hts_parse_format(htsFormat *format, const char *str) {
+ char fmt[8];
+ const char *cp = scan_keyword(str, ',', fmt, sizeof fmt);
+
+ format->version.minor = 0; // unknown
+ format->version.major = 0; // unknown
+
+ if (strcmp(fmt, "sam") == 0) {
+ format->category = sequence_data;
+ format->format = sam;
+ format->compression = no_compression;;
+ format->compression_level = 0;
+ } else if (strcmp(fmt, "bam") == 0) {
+ format->category = sequence_data;
+ format->format = bam;
+ format->compression = bgzf;
+ format->compression_level = -1;
+ } else if (strcmp(fmt, "cram") == 0) {
+ format->category = sequence_data;
+ format->format = cram;
+ format->compression = custom;
+ format->compression_level = -1;
+ } else if (strcmp(fmt, "vcf") == 0) {
+ format->category = variant_data;
+ format->format = vcf;
+ format->compression = no_compression;;
+ format->compression_level = 0;
+ } else if (strcmp(fmt, "bcf") == 0) {
+ format->category = variant_data;
+ format->format = bcf;
+ format->compression = bgzf;
+ format->compression_level = -1;
+ } else {
+ return -1;
+ }
+
+ return hts_parse_opt_list(format, cp);
+}
+
+
+/*
+ * Tokenise options as (key(=value)?,)*(key(=value)?)?
+ * NB: No provision for ',' appearing in the value!
+ * Add backslashing rules?
+ *
+ * This could be used as part of a general command line option parser or
+ * as a string concatenated onto the file open mode.
+ *
+ * Returns 0 on success
+ * -1 on failure.
+ */
+static int hts_process_opts(htsFile *fp, const char *opts) {
+ htsFormat fmt;
+
+ fmt.specific = NULL;
+ if (hts_parse_opt_list(&fmt, opts) != 0)
+ return -1;
+
+ if (hts_opt_apply(fp, fmt.specific) != 0) {
+ hts_opt_free(fmt.specific);
+ return -1;
+ }
+
+ hts_opt_free(fmt.specific);
+
+ return 0;
+}
+
+
+htsFile *hts_hopen(struct hFILE *hfile, const char *fn, const char *mode)
+{
+ htsFile *fp = (htsFile*)calloc(1, sizeof(htsFile));
+ char simple_mode[101], *cp, *opts;
+ simple_mode[100] = '\0';
+
+ if (fp == NULL) goto error;
+
+ fp->fn = strdup(fn);
+ fp->is_be = ed_is_big();
+
+ // Split mode into simple_mode,opts strings
+ if ((cp = strchr(mode, ','))) {
+ strncpy(simple_mode, mode, cp-mode <= 100 ? cp-mode : 100);
+ simple_mode[cp-mode] = '\0';
+ opts = cp+1;
+ } else {
+ strncpy(simple_mode, mode, 100);
+ opts = NULL;
+ }
+
+ if (strchr(simple_mode, 'r')) {
+ if (hts_detect_format(hfile, &fp->format) < 0) goto error;
+ }
+ else if (strchr(simple_mode, 'w') || strchr(simple_mode, 'a')) {
+ htsFormat *fmt = &fp->format;
+ fp->is_write = 1;
+
+ if (strchr(simple_mode, 'b')) fmt->format = binary_format;
+ else if (strchr(simple_mode, 'c')) fmt->format = cram;
+ else fmt->format = text_format;
+
+ if (strchr(simple_mode, 'z')) fmt->compression = bgzf;
+ else if (strchr(simple_mode, 'g')) fmt->compression = gzip;
+ else if (strchr(simple_mode, 'u')) fmt->compression = no_compression;
+ else {
+ // No compression mode specified, set to the default for the format
+ switch (fmt->format) {
+ case binary_format: fmt->compression = bgzf; break;
+ case cram: fmt->compression = custom; break;
+ case text_format: fmt->compression = no_compression; break;
+ default: abort();
+ }
+ }
+
+ // Fill in category (if determinable; e.g. 'b' could be BAM or BCF)
+ fmt->category = format_category(fmt->format);
+
+ fmt->version.major = fmt->version.minor = -1;
+ fmt->compression_level = -1;
+ fmt->specific = NULL;
+ }
+ else goto error;
+
+ switch (fp->format.format) {
+ case binary_format:
+ case bam:
+ case bcf:
+ fp->fp.bgzf = bgzf_hopen(hfile, simple_mode);
+ if (fp->fp.bgzf == NULL) goto error;
+ fp->is_bin = 1;
+ break;
+
+ case cram:
+ fp->fp.cram = cram_dopen(hfile, fn, simple_mode);
+ if (fp->fp.cram == NULL) goto error;
+ if (!fp->is_write)
+ cram_set_option(fp->fp.cram, CRAM_OPT_DECODE_MD, 1);
+ fp->is_cram = 1;
+ break;
+
+ case text_format:
+ case sam:
+ case vcf:
+ if (!fp->is_write) {
+ #if KS_BGZF
+ BGZF *gzfp = bgzf_hopen(hfile, simple_mode);
+ #else
+ // TODO Implement gzip hFILE adaptor
+ hclose(hfile); // This won't work, especially for stdin
+ gzFile gzfp = strcmp(fn, "-")? gzopen(fn, "rb") : gzdopen(fileno(stdin), "rb");
+ #endif
+ if (gzfp) fp->fp.voidp = ks_init(gzfp);
+ else goto error;
+ }
+ else if (fp->format.compression != no_compression) {
+ fp->fp.bgzf = bgzf_hopen(hfile, simple_mode);
+ if (fp->fp.bgzf == NULL) goto error;
+ }
+ else
+ fp->fp.hfile = hfile;
+ break;
+
+ default:
+ goto error;
+ }
+
+ if (opts)
+ hts_process_opts(fp, opts);
+
+ return fp;
+
+error:
+ if (hts_verbose >= 2)
+ fprintf(stderr, "[E::%s] fail to open file '%s'\n", __func__, fn);
+
+ if (fp) {
+ free(fp->fn);
+ free(fp->fn_aux);
+ free(fp);
+ }
+ return NULL;
+}
+
+int hts_close(htsFile *fp)
+{
+ int ret, save;
+
+ switch (fp->format.format) {
+ case binary_format:
+ case bam:
+ case bcf:
+ ret = bgzf_close(fp->fp.bgzf);
+ break;
+
+ case cram:
+ if (!fp->is_write) {
+ switch (cram_eof(fp->fp.cram)) {
+ case 2:
+ fprintf(stderr, "[W::%s] EOF marker is absent. The input is probably truncated.\n", __func__);
+ break;
+ case 0: /* not at EOF, but may not have wanted all seqs */
+ default: /* case 1, expected EOF */
+ break;
+ }
+ }
+ ret = cram_close(fp->fp.cram);
+ break;
+
+ case text_format:
+ case sam:
+ case vcf:
+ if (!fp->is_write) {
+ #if KS_BGZF
+ BGZF *gzfp = ((kstream_t*)fp->fp.voidp)->f;
+ ret = bgzf_close(gzfp);
+ #else
+ gzFile gzfp = ((kstream_t*)fp->fp.voidp)->f;
+ ret = gzclose(gzfp);
+ #endif
+ ks_destroy((kstream_t*)fp->fp.voidp);
+ }
+ else if (fp->format.compression != no_compression)
+ ret = bgzf_close(fp->fp.bgzf);
+ else
+ ret = hclose(fp->fp.hfile);
+ break;
+
+ default:
+ ret = -1;
+ break;
+ }
+
+ save = errno;
+ free(fp->fn);
+ free(fp->fn_aux);
+ free(fp->line.s);
+ free(fp);
+ errno = save;
+ return ret;
+}
+
+const htsFormat *hts_get_format(htsFile *fp)
+{
+ return fp? &fp->format : NULL;
+}
+
+const char *hts_format_file_extension(const htsFormat *format) {
+ if (!format)
+ return "?";
+
+ switch (format->format) {
+ case sam: return "sam";
+ case bam: return "bam";
+ case bai: return "bai";
+ case cram: return "cram";
+ case crai: return "crai";
+ case vcf: return "vcf";
+ case bcf: return "bcf";
+ case csi: return "csi";
+ case gzi: return "gzi";
+ case tbi: return "tbi";
+ case bed: return "bed";
+ default: return "?";
+ }
+}
+
+int hts_set_opt(htsFile *fp, enum hts_fmt_option opt, ...) {
+ int r;
+ va_list args;
+
+ if (opt == HTS_OPT_NTHREADS) {
+ va_start(args, opt);
+ int nthreads = va_arg(args, int);
+ va_end(args);
+ return hts_set_threads(fp, nthreads);
+ }
+
+ if (fp->format.format != cram)
+ return 0;
+
+ va_start(args, opt);
+ r = cram_set_voption(fp->fp.cram, opt, args);
+ va_end(args);
+
+ return r;
+}
+
+int hts_set_threads(htsFile *fp, int n)
+{
+ if (fp->format.compression == bgzf) {
+ return bgzf_mt(fp->fp.bgzf, n, 256);
+ } else if (fp->format.format == cram) {
+ return hts_set_opt(fp, CRAM_OPT_NTHREADS, n);
+ }
+ else return 0;
+}
+
+int hts_set_fai_filename(htsFile *fp, const char *fn_aux)
+{
+ free(fp->fn_aux);
+ if (fn_aux) {
+ fp->fn_aux = strdup(fn_aux);
+ if (fp->fn_aux == NULL) return -1;
+ }
+ else fp->fn_aux = NULL;
+
+ if (fp->format.format == cram)
+ if (cram_set_option(fp->fp.cram, CRAM_OPT_REFERENCE, fp->fn_aux))
+ return -1;
+
+ return 0;
+}
+
+// For VCF/BCF backward sweeper. Not exposing these functions because their
+// future is uncertain. Things will probably have to change with hFILE...
+BGZF *hts_get_bgzfp(htsFile *fp)
+{
+ if ( fp->is_bin )
+ return fp->fp.bgzf;
+ else
+ return ((kstream_t*)fp->fp.voidp)->f;
+}
+int hts_useek(htsFile *fp, long uoffset, int where)
+{
+ if ( fp->is_bin )
+ return bgzf_useek(fp->fp.bgzf, uoffset, where);
+ else
+ {
+ ks_rewind((kstream_t*)fp->fp.voidp);
+ ((kstream_t*)fp->fp.voidp)->seek_pos = uoffset;
+ return bgzf_useek(((kstream_t*)fp->fp.voidp)->f, uoffset, where);
+ }
+}
+long hts_utell(htsFile *fp)
+{
+ if ( fp->is_bin )
+ return bgzf_utell(fp->fp.bgzf);
+ else
+ return ((kstream_t*)fp->fp.voidp)->seek_pos;
+}
+
+int hts_getline(htsFile *fp, int delimiter, kstring_t *str)
+{
+ int ret, dret;
+ ret = ks_getuntil((kstream_t*)fp->fp.voidp, delimiter, str, &dret);
+ ++fp->lineno;
+ return ret;
+}
+
+char **hts_readlist(const char *string, int is_file, int *_n)
+{
+ int m = 0, n = 0, dret;
+ char **s = 0;
+ if ( is_file )
+ {
+#if KS_BGZF
+ BGZF *fp = bgzf_open(string, "r");
+#else
+ gzFile fp = gzopen(string, "r");
+#endif
+ if ( !fp ) return NULL;
+
+ kstream_t *ks;
+ kstring_t str;
+ str.s = 0; str.l = str.m = 0;
+ ks = ks_init(fp);
+ while (ks_getuntil(ks, KS_SEP_LINE, &str, &dret) >= 0)
+ {
+ if (str.l == 0) continue;
+ n++;
+ hts_expand(char*,n,m,s);
+ s[n-1] = strdup(str.s);
+ }
+ ks_destroy(ks);
+#if KS_BGZF
+ bgzf_close(fp);
+#else
+ gzclose(fp);
+#endif
+ free(str.s);
+ }
+ else
+ {
+ const char *q = string, *p = string;
+ while ( 1 )
+ {
+ if (*p == ',' || *p == 0)
+ {
+ n++;
+ hts_expand(char*,n,m,s);
+ s[n-1] = (char*)calloc(p - q + 1, 1);
+ strncpy(s[n-1], q, p - q);
+ q = p + 1;
+ }
+ if ( !*p ) break;
+ p++;
+ }
+ }
+ s = (char**)realloc(s, n * sizeof(char*));
+ *_n = n;
+ return s;
+}
+
+char **hts_readlines(const char *fn, int *_n)
+{
+ int m = 0, n = 0, dret;
+ char **s = 0;
+#if KS_BGZF
+ BGZF *fp = bgzf_open(fn, "r");
+#else
+ gzFile fp = gzopen(fn, "r");
+#endif
+ if ( fp ) { // read from file
+ kstream_t *ks;
+ kstring_t str;
+ str.s = 0; str.l = str.m = 0;
+ ks = ks_init(fp);
+ while (ks_getuntil(ks, KS_SEP_LINE, &str, &dret) >= 0) {
+ if (str.l == 0) continue;
+ if (m == n) {
+ m = m? m<<1 : 16;
+ s = (char**)realloc(s, m * sizeof(char*));
+ }
+ s[n++] = strdup(str.s);
+ }
+ ks_destroy(ks);
+ #if KS_BGZF
+ bgzf_close(fp);
+ #else
+ gzclose(fp);
+ #endif
+ s = (char**)realloc(s, n * sizeof(char*));
+ free(str.s);
+ } else if (*fn == ':') { // read from string
+ const char *q, *p;
+ for (q = p = fn + 1;; ++p)
+ if (*p == ',' || *p == 0) {
+ if (m == n) {
+ m = m? m<<1 : 16;
+ s = (char**)realloc(s, m * sizeof(char*));
+ }
+ s[n] = (char*)calloc(p - q + 1, 1);
+ strncpy(s[n++], q, p - q);
+ q = p + 1;
+ if (*p == 0) break;
+ }
+ } else return 0;
+ s = (char**)realloc(s, n * sizeof(char*));
+ *_n = n;
+ return s;
+}
+
+// DEPRECATED: To be removed in a future HTSlib release
+int hts_file_type(const char *fname)
+{
+ int len = strlen(fname);
+ if ( !strcasecmp(".vcf.gz",fname+len-7) ) return FT_VCF_GZ;
+ if ( !strcasecmp(".vcf",fname+len-4) ) return FT_VCF;
+ if ( !strcasecmp(".bcf",fname+len-4) ) return FT_BCF_GZ;
+ if ( !strcmp("-",fname) ) return FT_STDIN;
+
+ hFILE *f = hopen(fname, "r");
+ if (f == NULL) return 0;
+
+ htsFormat fmt;
+ if (hts_detect_format(f, &fmt) < 0) { hclose_abruptly(f); return 0; }
+ if (hclose(f) < 0) return 0;
+
+ switch (fmt.format) {
+ case vcf: return (fmt.compression == no_compression)? FT_VCF : FT_VCF_GZ;
+ case bcf: return (fmt.compression == no_compression)? FT_BCF : FT_BCF_GZ;
+ default: return 0;
+ }
+}
+
+/****************
+ *** Indexing ***
+ ****************/
+
+#define HTS_MIN_MARKER_DIST 0x10000
+
+// Finds the special meta bin
+// ((1<<(3 * n_lvls + 3)) - 1) / 7 + 1
+#define META_BIN(idx) ((idx)->n_bins + 1)
+
+#define pair64_lt(a,b) ((a).u < (b).u)
+
+#include "htslib/ksort.h"
+KSORT_INIT(_off, hts_pair64_t, pair64_lt)
+
+typedef struct {
+ int32_t m, n;
+ uint64_t loff;
+ hts_pair64_t *list;
+} bins_t;
+
+#include "htslib/khash.h"
+KHASH_MAP_INIT_INT(bin, bins_t)
+typedef khash_t(bin) bidx_t;
+
+typedef struct {
+ int32_t n, m;
+ uint64_t *offset;
+} lidx_t;
+
+struct __hts_idx_t {
+ int fmt, min_shift, n_lvls, n_bins;
+ uint32_t l_meta;
+ int32_t n, m;
+ uint64_t n_no_coor;
+ bidx_t **bidx;
+ lidx_t *lidx;
+ uint8_t *meta;
+ struct {
+ uint32_t last_bin, save_bin;
+ int last_coor, last_tid, save_tid, finished;
+ uint64_t last_off, save_off;
+ uint64_t off_beg, off_end;
+ uint64_t n_mapped, n_unmapped;
+ } z; // keep internal states
+};
+
+static inline void insert_to_b(bidx_t *b, int bin, uint64_t beg, uint64_t end)
+{
+ khint_t k;
+ bins_t *l;
+ int absent;
+ k = kh_put(bin, b, bin, &absent);
+ l = &kh_value(b, k);
+ if (absent) {
+ l->m = 1; l->n = 0;
+ l->list = (hts_pair64_t*)calloc(l->m, sizeof(hts_pair64_t));
+ }
+ if (l->n == l->m) {
+ l->m <<= 1;
+ l->list = (hts_pair64_t*)realloc(l->list, l->m * sizeof(hts_pair64_t));
+ }
+ l->list[l->n].u = beg;
+ l->list[l->n++].v = end;
+}
+
+static inline void insert_to_l(lidx_t *l, int64_t _beg, int64_t _end, uint64_t offset, int min_shift)
+{
+ int i, beg, end;
+ beg = _beg >> min_shift;
+ end = (_end - 1) >> min_shift;
+ if (l->m < end + 1) {
+ int old_m = l->m;
+ l->m = end + 1;
+ kroundup32(l->m);
+ l->offset = (uint64_t*)realloc(l->offset, l->m * sizeof(uint64_t));
+ memset(l->offset + old_m, 0xff, 8 * (l->m - old_m)); // fill l->offset with (uint64_t)-1
+ }
+ if (beg == end) { // to save a loop in this case
+ if (l->offset[beg] == (uint64_t)-1) l->offset[beg] = offset;
+ } else {
+ for (i = beg; i <= end; ++i)
+ if (l->offset[i] == (uint64_t)-1) l->offset[i] = offset;
+ }
+ if (l->n < end + 1) l->n = end + 1;
+}
+
+hts_idx_t *hts_idx_init(int n, int fmt, uint64_t offset0, int min_shift, int n_lvls)
+{
+ hts_idx_t *idx;
+ idx = (hts_idx_t*)calloc(1, sizeof(hts_idx_t));
+ if (idx == NULL) return NULL;
+ idx->fmt = fmt;
+ idx->min_shift = min_shift;
+ idx->n_lvls = n_lvls;
+ idx->n_bins = ((1<<(3 * n_lvls + 3)) - 1) / 7;
+ idx->z.save_bin = idx->z.save_tid = idx->z.last_tid = idx->z.last_bin = 0xffffffffu;
+ idx->z.save_off = idx->z.last_off = idx->z.off_beg = idx->z.off_end = offset0;
+ idx->z.last_coor = 0xffffffffu;
+ if (n) {
+ idx->n = idx->m = n;
+ idx->bidx = (bidx_t**)calloc(n, sizeof(bidx_t*));
+ if (idx->bidx == NULL) { free(idx); return NULL; }
+ idx->lidx = (lidx_t*) calloc(n, sizeof(lidx_t));
+ if (idx->lidx == NULL) { free(idx->bidx); free(idx); return NULL; }
+ }
+ return idx;
+}
+
+static void update_loff(hts_idx_t *idx, int i, int free_lidx)
+{
+ bidx_t *bidx = idx->bidx[i];
+ lidx_t *lidx = &idx->lidx[i];
+ khint_t k;
+ int l;
+ uint64_t offset0 = 0;
+ if (bidx) {
+ k = kh_get(bin, bidx, META_BIN(idx));
+ if (k != kh_end(bidx))
+ offset0 = kh_val(bidx, k).list[0].u;
+ for (l = 0; l < lidx->n && lidx->offset[l] == (uint64_t)-1; ++l)
+ lidx->offset[l] = offset0;
+ } else l = 1;
+ for (; l < lidx->n; ++l) // fill missing values
+ if (lidx->offset[l] == (uint64_t)-1)
+ lidx->offset[l] = lidx->offset[l-1];
+ if (bidx == 0) return;
+ for (k = kh_begin(bidx); k != kh_end(bidx); ++k) // set loff
+ if (kh_exist(bidx, k))
+ {
+ if ( kh_key(bidx, k) < idx->n_bins )
+ {
+ int bot_bin = hts_bin_bot(kh_key(bidx, k), idx->n_lvls);
+ // disable linear index if bot_bin out of bounds
+ kh_val(bidx, k).loff = bot_bin < lidx->n ? lidx->offset[bot_bin] : 0;
+ }
+ else
+ kh_val(bidx, k).loff = 0;
+ }
+ if (free_lidx) {
+ free(lidx->offset);
+ lidx->m = lidx->n = 0;
+ lidx->offset = 0;
+ }
+}
+
+static void compress_binning(hts_idx_t *idx, int i)
+{
+ bidx_t *bidx = idx->bidx[i];
+ khint_t k;
+ int l, m;
+ if (bidx == 0) return;
+ // merge a bin to its parent if the bin is too small
+ for (l = idx->n_lvls; l > 0; --l) {
+ unsigned start = hts_bin_first(l);
+ for (k = kh_begin(bidx); k != kh_end(bidx); ++k) {
+ bins_t *p, *q;
+ if (!kh_exist(bidx, k) || kh_key(bidx, k) >= idx->n_bins || kh_key(bidx, k) < start) continue;
+ p = &kh_value(bidx, k);
+ if (l < idx->n_lvls && p->n > 1) ks_introsort(_off, p->n, p->list);
+ if ((p->list[p->n - 1].v>>16) - (p->list[0].u>>16) < HTS_MIN_MARKER_DIST) {
+ khint_t kp;
+ kp = kh_get(bin, bidx, hts_bin_parent(kh_key(bidx, k)));
+ if (kp == kh_end(bidx)) continue;
+ q = &kh_val(bidx, kp);
+ if (q->n + p->n > q->m) {
+ q->m = q->n + p->n;
+ kroundup32(q->m);
+ q->list = (hts_pair64_t*)realloc(q->list, q->m * sizeof(hts_pair64_t));
+ }
+ memcpy(q->list + q->n, p->list, p->n * sizeof(hts_pair64_t));
+ q->n += p->n;
+ free(p->list);
+ kh_del(bin, bidx, k);
+ }
+ }
+ }
+ k = kh_get(bin, bidx, 0);
+ if (k != kh_end(bidx)) ks_introsort(_off, kh_val(bidx, k).n, kh_val(bidx, k).list);
+ // merge adjacent chunks that start from the same BGZF block
+ for (k = kh_begin(bidx); k != kh_end(bidx); ++k) {
+ bins_t *p;
+ if (!kh_exist(bidx, k) || kh_key(bidx, k) >= idx->n_bins) continue;
+ p = &kh_value(bidx, k);
+ for (l = 1, m = 0; l < p->n; ++l) {
+ if (p->list[m].v>>16 >= p->list[l].u>>16) {
+ if (p->list[m].v < p->list[l].v) p->list[m].v = p->list[l].v;
+ } else p->list[++m] = p->list[l];
+ }
+ p->n = m + 1;
+ }
+}
+
+void hts_idx_finish(hts_idx_t *idx, uint64_t final_offset)
+{
+ int i;
+ if (idx == NULL || idx->z.finished) return; // do not run this function on an empty index or multiple times
+ if (idx->z.save_tid >= 0) {
+ insert_to_b(idx->bidx[idx->z.save_tid], idx->z.save_bin, idx->z.save_off, final_offset);
+ insert_to_b(idx->bidx[idx->z.save_tid], META_BIN(idx), idx->z.off_beg, final_offset);
+ insert_to_b(idx->bidx[idx->z.save_tid], META_BIN(idx), idx->z.n_mapped, idx->z.n_unmapped);
+ }
+ for (i = 0; i < idx->n; ++i) {
+ update_loff(idx, i, (idx->fmt == HTS_FMT_CSI));
+ compress_binning(idx, i);
+ }
+ idx->z.finished = 1;
+}
+
+int hts_idx_push(hts_idx_t *idx, int tid, int beg, int end, uint64_t offset, int is_mapped)
+{
+ int bin;
+ if (tid<0) beg = -1, end = 0;
+ if (tid >= idx->m) { // enlarge the index
+ int32_t oldm = idx->m;
+ idx->m = idx->m? idx->m<<1 : 2;
+ idx->bidx = (bidx_t**)realloc(idx->bidx, idx->m * sizeof(bidx_t*));
+ idx->lidx = (lidx_t*) realloc(idx->lidx, idx->m * sizeof(lidx_t));
+ memset(&idx->bidx[oldm], 0, (idx->m - oldm) * sizeof(bidx_t*));
+ memset(&idx->lidx[oldm], 0, (idx->m - oldm) * sizeof(lidx_t));
+ }
+ if (idx->n < tid + 1) idx->n = tid + 1;
+ if (idx->z.finished) return 0;
+ if (idx->z.last_tid != tid || (idx->z.last_tid >= 0 && tid < 0)) { // change of chromosome
+ if ( tid>=0 && idx->n_no_coor )
+ {
+ if (hts_verbose >= 1) fprintf(stderr,"[E::%s] NO_COOR reads not in a single block at the end %d %d\n", __func__, tid,idx->z.last_tid);
+ return -1;
+ }
+ if (tid>=0 && idx->bidx[tid] != 0)
+ {
+ if (hts_verbose >= 1) fprintf(stderr, "[E::%s] chromosome blocks not continuous\n", __func__);
+ return -1;
+ }
+ idx->z.last_tid = tid;
+ idx->z.last_bin = 0xffffffffu;
+ } else if (tid >= 0 && idx->z.last_coor > beg) { // test if positions are out of order
+ if (hts_verbose >= 1) fprintf(stderr, "[E::%s] unsorted positions\n", __func__);
+ return -1;
+ }
+ if ( tid>=0 )
+ {
+ if (idx->bidx[tid] == 0) idx->bidx[tid] = kh_init(bin);
+ if ( is_mapped)
+ insert_to_l(&idx->lidx[tid], beg, end, idx->z.last_off, idx->min_shift); // last_off points to the start of the current record
+ }
+ else idx->n_no_coor++;
+ bin = hts_reg2bin(beg, end, idx->min_shift, idx->n_lvls);
+ if ((int)idx->z.last_bin != bin) { // then possibly write the binning index
+ if (idx->z.save_bin != 0xffffffffu) // save_bin==0xffffffffu only happens to the first record
+ insert_to_b(idx->bidx[idx->z.save_tid], idx->z.save_bin, idx->z.save_off, idx->z.last_off);
+ if (idx->z.last_bin == 0xffffffffu && idx->z.save_bin != 0xffffffffu) { // change of chr; keep meta information
+ idx->z.off_end = idx->z.last_off;
+ insert_to_b(idx->bidx[idx->z.save_tid], META_BIN(idx), idx->z.off_beg, idx->z.off_end);
+ insert_to_b(idx->bidx[idx->z.save_tid], META_BIN(idx), idx->z.n_mapped, idx->z.n_unmapped);
+ idx->z.n_mapped = idx->z.n_unmapped = 0;
+ idx->z.off_beg = idx->z.off_end;
+ }
+ idx->z.save_off = idx->z.last_off;
+ idx->z.save_bin = idx->z.last_bin = bin;
+ idx->z.save_tid = tid;
+ }
+ if (is_mapped) ++idx->z.n_mapped;
+ else ++idx->z.n_unmapped;
+ idx->z.last_off = offset;
+ idx->z.last_coor = beg;
+ return 0;
+}
+
+void hts_idx_destroy(hts_idx_t *idx)
+{
+ khint_t k;
+ int i;
+ if (idx == 0) return;
+
+ // For HTS_FMT_CRAI, idx actually points to a different type -- see sam.c
+ if (idx->fmt == HTS_FMT_CRAI) {
+ hts_cram_idx_t *cidx = (hts_cram_idx_t *) idx;
+ cram_index_free(cidx->cram);
+ free(cidx);
+ return;
+ }
+
+ for (i = 0; i < idx->m; ++i) {
+ bidx_t *bidx = idx->bidx[i];
+ free(idx->lidx[i].offset);
+ if (bidx == 0) continue;
+ for (k = kh_begin(bidx); k != kh_end(bidx); ++k)
+ if (kh_exist(bidx, k))
+ free(kh_value(bidx, k).list);
+ kh_destroy(bin, bidx);
+ }
+ free(idx->bidx); free(idx->lidx); free(idx->meta);
+ free(idx);
+}
+
+// The optimizer eliminates these ed_is_big() calls; still it would be good to
+// TODO Determine endianness at configure- or compile-time
+
+static inline ssize_t HTS_RESULT_USED idx_write_int32(BGZF *fp, int32_t x)
+{
+ if (ed_is_big()) x = ed_swap_4(x);
+ return bgzf_write(fp, &x, sizeof x);
+}
+
+static inline ssize_t HTS_RESULT_USED idx_write_uint32(BGZF *fp, uint32_t x)
+{
+ if (ed_is_big()) x = ed_swap_4(x);
+ return bgzf_write(fp, &x, sizeof x);
+}
+
+static inline ssize_t HTS_RESULT_USED idx_write_uint64(BGZF *fp, uint64_t x)
+{
+ if (ed_is_big()) x = ed_swap_8(x);
+ return bgzf_write(fp, &x, sizeof x);
+}
+
+static inline void swap_bins(bins_t *p)
+{
+ int i;
+ for (i = 0; i < p->n; ++i) {
+ ed_swap_8p(&p->list[i].u);
+ ed_swap_8p(&p->list[i].v);
+ }
+}
+
+static int hts_idx_save_core(const hts_idx_t *idx, BGZF *fp, int fmt)
+{
+ int32_t i, j;
+
+ #define check(ret) if ((ret) < 0) return -1
+
+ check(idx_write_int32(fp, idx->n));
+ if (fmt == HTS_FMT_TBI && idx->l_meta)
+ check(bgzf_write(fp, idx->meta, idx->l_meta));
+
+ for (i = 0; i < idx->n; ++i) {
+ khint_t k;
+ bidx_t *bidx = idx->bidx[i];
+ lidx_t *lidx = &idx->lidx[i];
+ // write binning index
+ check(idx_write_int32(fp, bidx? kh_size(bidx) : 0));
+ if (bidx)
+ for (k = kh_begin(bidx); k != kh_end(bidx); ++k)
+ if (kh_exist(bidx, k)) {
+ bins_t *p = &kh_value(bidx, k);
+ check(idx_write_uint32(fp, kh_key(bidx, k)));
+ if (fmt == HTS_FMT_CSI) check(idx_write_uint64(fp, p->loff));
+ //int j;for(j=0;j<p->n;++j)fprintf(stderr,"%d,%llx,%d,%llx:%llx\n",kh_key(bidx,k),kh_val(bidx, k).loff,j,p->list[j].u,p->list[j].v);
+ check(idx_write_int32(fp, p->n));
+ for (j = 0; j < p->n; ++j) {
+ check(idx_write_uint64(fp, p->list[j].u));
+ check(idx_write_uint64(fp, p->list[j].v));
+ }
+ }
+
+ // write linear index
+ if (fmt != HTS_FMT_CSI) {
+ check(idx_write_int32(fp, lidx->n));
+ for (j = 0; j < lidx->n; ++j)
+ check(idx_write_uint64(fp, lidx->offset[j]));
+ }
+ }
+
+ check(idx_write_uint64(fp, idx->n_no_coor));
+ return 0;
+ #undef check
+}
+
+int hts_idx_save(const hts_idx_t *idx, const char *fn, int fmt)
+{
+ int ret, save;
+ char *fnidx = (char*)calloc(1, strlen(fn) + 5);
+ if (fnidx == NULL) return -1;
+
+ strcpy(fnidx, fn);
+ switch (fmt) {
+ case HTS_FMT_BAI: strcat(fnidx, ".bai"); break;
+ case HTS_FMT_CSI: strcat(fnidx, ".csi"); break;
+ case HTS_FMT_TBI: strcat(fnidx, ".tbi"); break;
+ default: abort();
+ }
+
+ ret = hts_idx_save_as(idx, fn, fnidx, fmt);
+ save = errno;
+ free(fnidx);
+ errno = save;
+ return ret;
+}
+
+int hts_idx_save_as(const hts_idx_t *idx, const char *fn, const char *fnidx, int fmt)
+{
+ BGZF *fp;
+
+ #define check(ret) if ((ret) < 0) goto fail
+
+ if (fnidx == NULL) return hts_idx_save(idx, fn, fmt);
+
+ fp = bgzf_open(fnidx, (fmt == HTS_FMT_BAI)? "wu" : "w");
+ if (fp == NULL) return -1;
+
+ if (fmt == HTS_FMT_CSI) {
+ check(bgzf_write(fp, "CSI\1", 4));
+ check(idx_write_int32(fp, idx->min_shift));
+ check(idx_write_int32(fp, idx->n_lvls));
+ check(idx_write_uint32(fp, idx->l_meta));
+ if (idx->l_meta) check(bgzf_write(fp, idx->meta, idx->l_meta));
+ } else if (fmt == HTS_FMT_TBI) {
+ check(bgzf_write(fp, "TBI\1", 4));
+ } else if (fmt == HTS_FMT_BAI) {
+ check(bgzf_write(fp, "BAI\1", 4));
+ } else abort();
+
+ check(hts_idx_save_core(idx, fp, fmt));
+
+ return bgzf_close(fp);
+ #undef check
+
+fail:
+ bgzf_close(fp);
+ return -1;
+}
+
+static int hts_idx_load_core(hts_idx_t *idx, BGZF *fp, int fmt)
+{
+ int32_t i, n, is_be;
+ is_be = ed_is_big();
+ if (idx == NULL) return -4;
+ for (i = 0; i < idx->n; ++i) {
+ bidx_t *h;
+ lidx_t *l = &idx->lidx[i];
+ uint32_t key;
+ int j, absent;
+ bins_t *p;
+ h = idx->bidx[i] = kh_init(bin);
+ if (bgzf_read(fp, &n, 4) != 4) return -1;
+ if (is_be) ed_swap_4p(&n);
+ for (j = 0; j < n; ++j) {
+ khint_t k;
+ if (bgzf_read(fp, &key, 4) != 4) return -1;
+ if (is_be) ed_swap_4p(&key);
+ k = kh_put(bin, h, key, &absent);
+ if (absent <= 0) return -3; // Duplicate bin number
+ p = &kh_val(h, k);
+ if (fmt == HTS_FMT_CSI) {
+ if (bgzf_read(fp, &p->loff, 8) != 8) return -1;
+ if (is_be) ed_swap_8p(&p->loff);
+ } else p->loff = 0;
+ if (bgzf_read(fp, &p->n, 4) != 4) return -1;
+ if (is_be) ed_swap_4p(&p->n);
+ p->m = p->n;
+ p->list = (hts_pair64_t*)malloc(p->m * sizeof(hts_pair64_t));
+ if (p->list == NULL) return -2;
+ if (bgzf_read(fp, p->list, p->n<<4) != p->n<<4) return -1;
+ if (is_be) swap_bins(p);
+ }
+ if (fmt != HTS_FMT_CSI) { // load linear index
+ int j;
+ if (bgzf_read(fp, &l->n, 4) != 4) return -1;
+ if (is_be) ed_swap_4p(&l->n);
+ l->m = l->n;
+ l->offset = (uint64_t*)malloc(l->n * sizeof(uint64_t));
+ if (l->offset == NULL) return -2;
+ if (bgzf_read(fp, l->offset, l->n << 3) != l->n << 3) return -1;
+ if (is_be) for (j = 0; j < l->n; ++j) ed_swap_8p(&l->offset[j]);
+ for (j = 1; j < l->n; ++j) // fill missing values; may happen given older samtools and tabix
+ if (l->offset[j] == 0) l->offset[j] = l->offset[j-1];
+ update_loff(idx, i, 1);
+ }
+ }
+ if (bgzf_read(fp, &idx->n_no_coor, 8) != 8) idx->n_no_coor = 0;
+ if (is_be) ed_swap_8p(&idx->n_no_coor);
+ return 0;
+}
+
+static hts_idx_t *hts_idx_load_local(const char *fn)
+{
+ uint8_t magic[4];
+ int i, is_be;
+ hts_idx_t *idx = NULL;
+ uint8_t *meta = NULL;
+ BGZF *fp = bgzf_open(fn, "r");
+ if (fp == NULL) return NULL;
+ is_be = ed_is_big();
+ if (bgzf_read(fp, magic, 4) != 4) goto fail;
+
+ if (memcmp(magic, "CSI\1", 4) == 0) {
+ uint32_t x[3], n;
+ if (bgzf_read(fp, x, 12) != 12) goto fail;
+ if (is_be) for (i = 0; i < 3; ++i) ed_swap_4p(&x[i]);
+ if (x[2]) {
+ if ((meta = (uint8_t*)malloc(x[2])) == NULL) goto fail;
+ if (bgzf_read(fp, meta, x[2]) != x[2]) goto fail;
+ }
+ if (bgzf_read(fp, &n, 4) != 4) goto fail;
+ if (is_be) ed_swap_4p(&n);
+ if ((idx = hts_idx_init(n, HTS_FMT_CSI, 0, x[0], x[1])) == NULL) goto fail;
+ idx->l_meta = x[2];
+ idx->meta = meta;
+ meta = NULL;
+ if (hts_idx_load_core(idx, fp, HTS_FMT_CSI) < 0) goto fail;
+ }
+ else if (memcmp(magic, "TBI\1", 4) == 0) {
+ uint32_t x[8];
+ if (bgzf_read(fp, x, 32) != 32) goto fail;
+ if (is_be) for (i = 0; i < 8; ++i) ed_swap_4p(&x[i]);
+ if ((idx = hts_idx_init(x[0], HTS_FMT_TBI, 0, 14, 5)) == NULL) goto fail;
+ idx->l_meta = 28 + x[7];
+ if ((idx->meta = (uint8_t*)malloc(idx->l_meta)) == NULL) goto fail;
+ memcpy(idx->meta, &x[1], 28);
+ if (bgzf_read(fp, idx->meta + 28, x[7]) != x[7]) goto fail;
+ if (hts_idx_load_core(idx, fp, HTS_FMT_TBI) < 0) goto fail;
+ }
+ else if (memcmp(magic, "BAI\1", 4) == 0) {
+ uint32_t n;
+ if (bgzf_read(fp, &n, 4) != 4) goto fail;
+ if (is_be) ed_swap_4p(&n);
+ idx = hts_idx_init(n, HTS_FMT_BAI, 0, 14, 5);
+ if (hts_idx_load_core(idx, fp, HTS_FMT_BAI) < 0) goto fail;
+ }
+ else { errno = EINVAL; goto fail; }
+
+ bgzf_close(fp);
+ return idx;
+
+fail:
+ bgzf_close(fp);
+ hts_idx_destroy(idx);
+ free(meta);
+ return NULL;
+}
+
+void hts_idx_set_meta(hts_idx_t *idx, int l_meta, uint8_t *meta, int is_copy)
+{
+ if (idx->meta) free(idx->meta);
+ idx->l_meta = l_meta;
+ if (is_copy) {
+ idx->meta = (uint8_t*)malloc(l_meta);
+ memcpy(idx->meta, meta, l_meta);
+ } else idx->meta = meta;
+}
+
+uint8_t *hts_idx_get_meta(hts_idx_t *idx, int *l_meta)
+{
+ *l_meta = idx->l_meta;
+ return idx->meta;
+}
+
+const char **hts_idx_seqnames(const hts_idx_t *idx, int *n, hts_id2name_f getid, void *hdr)
+{
+ if ( !idx->n )
+ {
+ *n = 0;
+ return NULL;
+ }
+
+ int tid = 0, i;
+ const char **names = (const char**) calloc(idx->n,sizeof(const char*));
+ for (i=0; i<idx->n; i++)
+ {
+ bidx_t *bidx = idx->bidx[i];
+ if ( !bidx ) continue;
+ names[tid++] = getid(hdr,i);
+ }
+ *n = tid;
+ return names;
+}
+
+int hts_idx_get_stat(const hts_idx_t* idx, int tid, uint64_t* mapped, uint64_t* unmapped)
+{
+ if ( idx->fmt == HTS_FMT_CRAI ) {
+ *mapped = 0; *unmapped = 0;
+ return -1;
+ }
+
+ bidx_t *h = idx->bidx[tid];
+ khint_t k = kh_get(bin, h, META_BIN(idx));
+ if (k != kh_end(h)) {
+ *mapped = kh_val(h, k).list[1].u;
+ *unmapped = kh_val(h, k).list[1].v;
+ return 0;
+ } else {
+ *mapped = 0; *unmapped = 0;
+ return -1;
+ }
+}
+
+uint64_t hts_idx_get_n_no_coor(const hts_idx_t* idx)
+{
+ return idx->n_no_coor;
+}
+
+/****************
+ *** Iterator ***
+ ****************/
+
+static inline int reg2bins(int64_t beg, int64_t end, hts_itr_t *itr, int min_shift, int n_lvls)
+{
+ int l, t, s = min_shift + (n_lvls<<1) + n_lvls;
+ if (beg >= end) return 0;
+ if (end >= 1LL<<s) end = 1LL<<s;
+ for (--end, l = 0, t = 0; l <= n_lvls; s -= 3, t += 1<<((l<<1)+l), ++l) {
+ int b, e, n, i;
+ b = t + (beg>>s); e = t + (end>>s); n = e - b + 1;
+ if (itr->bins.n + n > itr->bins.m) {
+ itr->bins.m = itr->bins.n + n;
+ kroundup32(itr->bins.m);
+ itr->bins.a = (int*)realloc(itr->bins.a, sizeof(int) * itr->bins.m);
+ }
+ for (i = b; i <= e; ++i) itr->bins.a[itr->bins.n++] = i;
+ }
+ return itr->bins.n;
+}
+
+hts_itr_t *hts_itr_query(const hts_idx_t *idx, int tid, int beg, int end, hts_readrec_func *readrec)
+{
+ int i, n_off, l, bin;
+ hts_pair64_t *off;
+ khint_t k;
+ bidx_t *bidx;
+ uint64_t min_off;
+ hts_itr_t *iter = 0;
+ if (tid < 0) {
+ int finished0 = 0;
+ uint64_t off0 = (uint64_t)-1;
+ khint_t k;
+ switch (tid) {
+ case HTS_IDX_START:
+ // Find the smallest offset, note that sequence ids may not be ordered sequentially
+ for (i=0; i<idx->n; i++)
+ {
+ bidx = idx->bidx[i];
+ k = kh_get(bin, bidx, META_BIN(idx));
+ if (k == kh_end(bidx)) continue;
+ if ( off0 > kh_val(bidx, k).list[0].u ) off0 = kh_val(bidx, k).list[0].u;
+ }
+ if ( off0==(uint64_t)-1 && idx->n_no_coor ) off0 = 0; // only no-coor reads in this bam
+ break;
+
+ case HTS_IDX_NOCOOR:
+ if ( idx->n>0 )
+ {
+ bidx = idx->bidx[idx->n - 1];
+ k = kh_get(bin, bidx, META_BIN(idx));
+ if (k != kh_end(bidx)) off0 = kh_val(bidx, k).list[0].v;
+ }
+ if ( off0==(uint64_t)-1 && idx->n_no_coor ) off0 = 0; // only no-coor reads in this bam
+ break;
+
+ case HTS_IDX_REST:
+ off0 = 0;
+ break;
+
+ case HTS_IDX_NONE:
+ finished0 = 1;
+ off0 = 0;
+ break;
+
+ default:
+ return 0;
+ }
+ if (off0 != (uint64_t)-1) {
+ iter = (hts_itr_t*)calloc(1, sizeof(hts_itr_t));
+ iter->read_rest = 1;
+ iter->finished = finished0;
+ iter->curr_off = off0;
+ iter->readrec = readrec;
+ return iter;
+ } else return 0;
+ }
+
+ if (beg < 0) beg = 0;
+ if (end < beg) return 0;
+ if (tid >= idx->n || (bidx = idx->bidx[tid]) == NULL) return 0;
+
+ iter = (hts_itr_t*)calloc(1, sizeof(hts_itr_t));
+ iter->tid = tid, iter->beg = beg, iter->end = end; iter->i = -1;
+ iter->readrec = readrec;
+
+ // compute min_off
+ bin = hts_bin_first(idx->n_lvls) + (beg>>idx->min_shift);
+ do {
+ int first;
+ k = kh_get(bin, bidx, bin);
+ if (k != kh_end(bidx)) break;
+ first = (hts_bin_parent(bin)<<3) + 1;
+ if (bin > first) --bin;
+ else bin = hts_bin_parent(bin);
+ } while (bin);
+ if (bin == 0) k = kh_get(bin, bidx, bin);
+ min_off = k != kh_end(bidx)? kh_val(bidx, k).loff : 0;
+ // retrieve bins
+ reg2bins(beg, end, iter, idx->min_shift, idx->n_lvls);
+ for (i = n_off = 0; i < iter->bins.n; ++i)
+ if ((k = kh_get(bin, bidx, iter->bins.a[i])) != kh_end(bidx))
+ n_off += kh_value(bidx, k).n;
+ if (n_off == 0) return iter;
+ off = (hts_pair64_t*)calloc(n_off, sizeof(hts_pair64_t));
+ for (i = n_off = 0; i < iter->bins.n; ++i) {
+ if ((k = kh_get(bin, bidx, iter->bins.a[i])) != kh_end(bidx)) {
+ int j;
+ bins_t *p = &kh_value(bidx, k);
+ for (j = 0; j < p->n; ++j)
+ if (p->list[j].v > min_off) off[n_off++] = p->list[j];
+ }
+ }
+ if (n_off == 0) {
+ free(off); return iter;
+ }
+ ks_introsort(_off, n_off, off);
+ // resolve completely contained adjacent blocks
+ for (i = 1, l = 0; i < n_off; ++i)
+ if (off[l].v < off[i].v) off[++l] = off[i];
+ n_off = l + 1;
+ // resolve overlaps between adjacent blocks; this may happen due to the merge in indexing
+ for (i = 1; i < n_off; ++i)
+ if (off[i-1].v >= off[i].u) off[i-1].v = off[i].u;
+ // merge adjacent blocks
+ for (i = 1, l = 0; i < n_off; ++i) {
+ if (off[l].v>>16 == off[i].u>>16) off[l].v = off[i].v;
+ else off[++l] = off[i];
+ }
+ n_off = l + 1;
+ iter->n_off = n_off; iter->off = off;
+ return iter;
+}
+
+void hts_itr_destroy(hts_itr_t *iter)
+{
+ if (iter) { free(iter->off); free(iter->bins.a); free(iter); }
+}
+
+static inline long long push_digit(long long i, char c)
+{
+ // ensure subtraction occurs first, avoiding overflow for >= MAX-48 or so
+ int digit = c - '0';
+ return 10 * i + digit;
+}
+
+long long hts_parse_decimal(const char *str, char **strend, int flags)
+{
+ long long n = 0;
+ int decimals = 0, e = 0, lost = 0;
+ char sign = '+', esign = '+';
+ const char *s;
+
+ while (isspace(*str)) str++;
+ s = str;
+
+ if (*s == '+' || *s == '-') sign = *s++;
+ while (*s)
+ if (isdigit(*s)) n = push_digit(n, *s++);
+ else if (*s == ',' && (flags & HTS_PARSE_THOUSANDS_SEP)) s++;
+ else break;
+
+ if (*s == '.') {
+ s++;
+ while (isdigit(*s)) decimals++, n = push_digit(n, *s++);
+ }
+
+ if (*s == 'E' || *s == 'e') {
+ s++;
+ if (*s == '+' || *s == '-') esign = *s++;
+ while (isdigit(*s)) e = push_digit(e, *s++);
+ if (esign == '-') e = -e;
+ }
+
+ e -= decimals;
+ while (e > 0) n *= 10, e--;
+ while (e < 0) lost += n % 10, n /= 10, e++;
+
+ if (lost > 0 && hts_verbose >= 3)
+ fprintf(stderr, "[W::%s] discarding fractional part of %.*s\n",
+ __func__, (int)(s - str), str);
+
+ if (strend) *strend = (char *) s;
+ else if (*s && hts_verbose >= 2)
+ fprintf(stderr, "[W::%s] ignoring unknown characters after %.*s[%s]\n",
+ __func__, (int)(s - str), str, s);
+
+ return (sign == '+')? n : -n;
+}
+
+const char *hts_parse_reg(const char *s, int *beg, int *end)
+{
+ char *hyphen;
+ const char *colon = strrchr(s, ':');
+ if (colon == NULL) {
+ *beg = 0; *end = INT_MAX;
+ return s + strlen(s);
+ }
+
+ *beg = hts_parse_decimal(colon+1, &hyphen, HTS_PARSE_THOUSANDS_SEP) - 1;
+ if (*beg < 0) *beg = 0;
+
+ if (*hyphen == '\0') *end = INT_MAX;
+ else if (*hyphen == '-') *end = hts_parse_decimal(hyphen+1, NULL, HTS_PARSE_THOUSANDS_SEP);
+ else return NULL;
+
+ if (*beg >= *end) return NULL;
+ return colon;
+}
+
+hts_itr_t *hts_itr_querys(const hts_idx_t *idx, const char *reg, hts_name2id_f getid, void *hdr, hts_itr_query_func *itr_query, hts_readrec_func *readrec)
+{
+ int tid, beg, end;
+ const char *q;
+
+ if (strcmp(reg, ".") == 0)
+ return itr_query(idx, HTS_IDX_START, 0, 0, readrec);
+ else if (strcmp(reg, "*") == 0)
+ return itr_query(idx, HTS_IDX_NOCOOR, 0, 0, readrec);
+
+ q = hts_parse_reg(reg, &beg, &end);
+ if (q) {
+ char *tmp = (char*)alloca(q - reg + 1);
+ strncpy(tmp, reg, q - reg);
+ tmp[q - reg] = 0;
+ tid = getid(hdr, tmp);
+ }
+ else {
+ // not parsable as a region, but possibly a sequence named "foo:a"
+ tid = getid(hdr, reg);
+ beg = 0; end = INT_MAX;
+ }
+
+ if (tid < 0) return NULL;
+ return itr_query(idx, tid, beg, end, readrec);
+}
+
+int hts_itr_next(BGZF *fp, hts_itr_t *iter, void *r, void *data)
+{
+ int ret, tid, beg, end;
+ if (iter == NULL || iter->finished) return -1;
+ if (iter->read_rest) {
+ if (iter->curr_off) { // seek to the start
+ if (bgzf_seek(fp, iter->curr_off, SEEK_SET) < 0) return -1;
+ iter->curr_off = 0; // only seek once
+ }
+ ret = iter->readrec(fp, data, r, &tid, &beg, &end);
+ if (ret < 0) iter->finished = 1;
+ iter->curr_tid = tid;
+ iter->curr_beg = beg;
+ iter->curr_end = end;
+ return ret;
+ }
+ if (iter->off == 0) return -1;
+ for (;;) {
+ if (iter->curr_off == 0 || iter->curr_off >= iter->off[iter->i].v) { // then jump to the next chunk
+ if (iter->i == iter->n_off - 1) { ret = -1; break; } // no more chunks
+ if (iter->i < 0 || iter->off[iter->i].v != iter->off[iter->i+1].u) { // not adjacent chunks; then seek
+ if (bgzf_seek(fp, iter->off[iter->i+1].u, SEEK_SET) < 0) return -1;
+ iter->curr_off = bgzf_tell(fp);
+ }
+ ++iter->i;
+ }
+ if ((ret = iter->readrec(fp, data, r, &tid, &beg, &end)) >= 0) {
+ iter->curr_off = bgzf_tell(fp);
+ if (tid != iter->tid || beg >= iter->end) { // no need to proceed
+ ret = -1; break;
+ } else if (end > iter->beg && iter->end > beg) {
+ iter->curr_tid = tid;
+ iter->curr_beg = beg;
+ iter->curr_end = end;
+ return ret;
+ }
+ } else break; // end of file or error
+ }
+ iter->finished = 1;
+ return ret;
+}
+
+/**********************
+ *** Retrieve index ***
+ **********************/
+
+static char *test_and_fetch(const char *fn)
+{
+ FILE *fp;
+ if (hisremote(fn)) {
+ const int buf_size = 1 * 1024 * 1024;
+ hFILE *fp_remote;
+ uint8_t *buf;
+ int l;
+ const char *p;
+ for (p = fn + strlen(fn) - 1; p >= fn; --p)
+ if (*p == '/') break;
+ ++p; // p now points to the local file name
+ // Attempt to open local file first
+ if ((fp = fopen((char*)p, "rb")) != 0)
+ {
+ fclose(fp);
+ return (char*)p;
+ }
+ // Attempt to open remote file. Stay quiet on failure, it is OK to fail when trying first .csi then .tbi index.
+ if ((fp_remote = hopen(fn, "r")) == 0) return 0;
+ if ((fp = fopen(p, "w")) == 0) {
+ if (hts_verbose >= 1) fprintf(stderr, "[E::%s] fail to create file '%s' in the working directory\n", __func__, p);
+ hclose_abruptly(fp_remote);
+ return 0;
+ }
+ if (hts_verbose >= 3) fprintf(stderr, "[M::%s] downloading file '%s' to local directory\n", __func__, fn);
+ buf = (uint8_t*)calloc(buf_size, 1);
+ while ((l = hread(fp_remote, buf, buf_size)) > 0) fwrite(buf, 1, l, fp);
+ free(buf);
+ fclose(fp);
+ if (hclose(fp_remote) != 0) fprintf(stderr, "[E::%s] fail to close remote file '%s'\n", __func__, fn);
+ return (char*)p;
+ } else {
+ if ((fp = fopen(fn, "rb")) == 0) return 0;
+ fclose(fp);
+ return (char*)fn;
+ }
+}
+
+char *hts_idx_getfn(const char *fn, const char *ext)
+{
+ int i, l_fn, l_ext;
+ char *fnidx, *ret;
+ l_fn = strlen(fn); l_ext = strlen(ext);
+ fnidx = (char*)calloc(l_fn + l_ext + 1, 1);
+ strcpy(fnidx, fn); strcpy(fnidx + l_fn, ext);
+ if ((ret = test_and_fetch(fnidx)) == 0) {
+ for (i = l_fn - 1; i > 0; --i)
+ if (fnidx[i] == '.') break;
+ strcpy(fnidx + i, ext);
+ ret = test_and_fetch(fnidx);
+ }
+ if (ret == 0) {
+ free(fnidx);
+ return 0;
+ }
+ l_fn = strlen(ret);
+ memmove(fnidx, ret, l_fn + 1);
+ return fnidx;
+}
+
+hts_idx_t *hts_idx_load(const char *fn, int fmt)
+{
+ char *fnidx;
+ hts_idx_t *idx;
+ fnidx = hts_idx_getfn(fn, ".csi");
+ if (! fnidx) fnidx = hts_idx_getfn(fn, fmt == HTS_FMT_BAI? ".bai" : ".tbi");
+ if (fnidx == 0) return 0;
+
+ idx = hts_idx_load2(fn, fnidx);
+ free(fnidx);
+ return idx;
+}
+
+hts_idx_t *hts_idx_load2(const char *fn, const char *fnidx)
+{
+ // Check that the index file is up to date, the main file might have changed
+ struct stat stat_idx,stat_main;
+ if ( !stat(fn, &stat_main) && !stat(fnidx, &stat_idx) )
+ {
+ if ( stat_idx.st_mtime < stat_main.st_mtime )
+ fprintf(stderr, "Warning: The index file is older than the data file: %s\n", fnidx);
+ }
+
+ return hts_idx_load_local(fnidx);
+}
--- /dev/null
+/* hts_internal.h -- internal functions; not part of the public API.
+
+ Copyright (C) 2015-2016 Genome Research Ltd.
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_HTS_INTERNAL_H
+#define HTSLIB_HTS_INTERNAL_H
+
+#include <stddef.h>
+#include <ctype.h>
+
+#include "htslib/hts.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+// The <ctype.h> functions operate on ints such as are returned by fgetc(),
+// i.e., characters represented as unsigned-char-valued ints, or EOF.
+// To operate on plain chars (and to avoid warnings on some platforms),
+// technically one must cast to unsigned char everywhere (see CERT STR37-C)
+// or less painfully use these *_c() functions that operate on plain chars
+// (but not EOF, which must be considered separately where it is applicable).
+// TODO We may eventually wish to implement these functions directly without
+// using their <ctype.h> equivalents, and thus make them immune to locales.
+static inline int isalnum_c(char c) { return isalnum((unsigned char) c); }
+static inline int isalpha_c(char c) { return isalpha((unsigned char) c); }
+static inline int isdigit_c(char c) { return isdigit((unsigned char) c); }
+static inline int isgraph_c(char c) { return isgraph((unsigned char) c); }
+static inline int islower_c(char c) { return islower((unsigned char) c); }
+static inline int isprint_c(char c) { return isprint((unsigned char) c); }
+static inline int isspace_c(char c) { return isspace((unsigned char) c); }
+static inline int isupper_c(char c) { return isupper((unsigned char) c); }
+static inline char tolower_c(char c) { return tolower((unsigned char) c); }
+static inline char toupper_c(char c) { return toupper((unsigned char) c); }
+
+
+struct cram_fd;
+
+char *hts_idx_getfn(const char *fn, const char *ext);
+
+// The CRAM implementation stores the loaded index within the cram_fd rather
+// than separately as is done elsewhere in htslib. So if p is a pointer to
+// an hts_idx_t with p->fmt == HTS_FMT_CRAI, then it actually points to an
+// hts_cram_idx_t and should be cast accordingly.
+typedef struct hts_cram_idx_t {
+ int fmt;
+ struct cram_fd *cram;
+} hts_cram_idx_t;
+
+
+struct hts_path_itr {
+ kstring_t path, entry;
+ void *dirv; // DIR * privately
+ const char *pathdir, *prefix, *suffix;
+ size_t prefix_len, suffix_len, entry_dir_l;
+};
+
+void hts_path_itr_setup(struct hts_path_itr *itr, const char *path,
+ const char *builtin_path, const char *prefix, size_t prefix_len,
+ const char *suffix, size_t suffix_len);
+
+const char *hts_path_itr_next(struct hts_path_itr *itr);
+
+void *load_plugin(void **pluginp, const char *filename, const char *symbol);
+void *plugin_sym(void *plugin, const char *name, const char **errmsg);
+void close_plugin(void *plugin);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+.TH htsfile 1 "22 April 2016" "htslib-1.3.1" "Bioinformatics tools"
+.SH NAME
+htsfile \- identify high-throughput sequencing data files
+.\"
+.\" Copyright (C) 2015 Genome Research Ltd.
+.\"
+.\" Author: John Marshall <jm18@sanger.ac.uk>
+.\"
+.\" Permission is hereby granted, free of charge, to any person obtaining a
+.\" copy of this software and associated documentation files (the "Software"),
+.\" to deal in the Software without restriction, including without limitation
+.\" the rights to use, copy, modify, merge, publish, distribute, sublicense,
+.\" and/or sell copies of the Software, and to permit persons to whom the
+.\" Software is furnished to do so, subject to the following conditions:
+.\"
+.\" The above copyright notice and this permission notice shall be included in
+.\" all copies or substantial portions of the Software.
+.\"
+.\" THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+.\" IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+.\" FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+.\" THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+.\" LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+.\" FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+.\" DEALINGS IN THE SOFTWARE.
+.\"
+.SH SYNOPSIS
+.B htsfile
+.RB [ -chHv ]
+.IR FILE ...
+.SH DESCRIPTION
+The \fBhtsfile\fR utility attempts to identify what kind of high-throughput
+sequencing data files the specified files are, and provides minimal viewing
+capabilities for some kinds of data file.
+.P
+It can identify sequencing data files such as SAM, BAM, and CRAM;
+variant calling data files such as VCF and BCF;
+index files used to index these data files;
+and compressed versions of many of them.
+.P
+For each \fIFILE\fR given, \fBhtsfile\fP prints a description of the file
+format determined, using similar keyword conventions to \fBfile\fP(1):
+"text" indicates a textual file that can probably be viewed on a terminal;
+"data" indicates binary data;
+"sequence", "variant calling", and "index" indicate different categories of
+data file.
+When it can be identified, the name of the particular file format (such as
+"BAM" or "VCF") is printed at the start of the description.
+.P
+When used to view file contents as text, \fBhtsfile\fP can optionally show
+only headers or only data records, but has no other filtering capabilities.
+Use \fBsamtools\fR or \fBbcftools\fR if you need more extensive viewing or
+filtering capabilities.
+.P
+The following options are accepted:
+.TP 4n
+.BR -c ", " --view
+Instead of identifying the specified files, display a textual representation
+of their contents on standard output.
+.TP
+.BR -h ", " --header-only
+Display data file headers only.
+Implies \fB--view\fR.
+.TP
+.BR -H ", " --no-header
+When viewing files, display data records only.
+.TP
+.BR -v ", " --verbose
+Display additional warnings and diagnostic messages.
+Using \fB--verbose\fR repeatedly further raises the verbosity.
+.PP
+.SH SEE ALSO
+.IR bcftools (1),
+.IR file (1),
+.IR samtools (1)
--- /dev/null
+/* htsfile.c -- file identifier and minimal viewer.
+
+ Copyright (C) 2014-2016 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <errno.h>
+#include <stdio.h>
+#include <stdlib.h>
+#include <getopt.h>
+#include <unistd.h>
+
+#include "htslib/hfile.h"
+#include "htslib/hts.h"
+#include "htslib/sam.h"
+#include "htslib/vcf.h"
+
+enum { identify, view_headers, view_all } mode = identify;
+int show_headers = 1;
+int status = EXIT_SUCCESS; /* Exit status from main */
+
+static htsFile *dup_stdout(const char *mode)
+{
+ int fd = dup(STDOUT_FILENO);
+ if (fd < 0) {
+ perror("htsfile: Couldn't duplicate stdout");
+ return NULL;
+ }
+ hFILE *hfp = hdopen(fd, mode);
+ return hfp? hts_hopen(hfp, "-", mode) : NULL;
+}
+
+static int view_sam(hFILE *hfp, const char *filename)
+{
+ samFile *in = hts_hopen(hfp, filename, "r");
+ bam_hdr_t *hdr = NULL;
+ samFile *out = NULL;
+ if (in == NULL) {
+ status = EXIT_FAILURE;
+ return 0;
+ }
+ hdr = sam_hdr_read(in);
+ if (hdr == NULL) {
+ status = EXIT_FAILURE;
+ goto clean;
+ }
+ out = dup_stdout("w");
+ if (out == NULL) {
+ status = EXIT_FAILURE;
+ goto clean;
+ }
+
+ if (show_headers) {
+ if (sam_hdr_write(out, hdr) != 0) {
+ status = EXIT_FAILURE;
+ goto clean;
+ }
+ }
+ if (mode == view_all) {
+ bam1_t *b = bam_init1();
+ int ret;
+ while ((ret = sam_read1(in, hdr, b)) >= 0) {
+ if (sam_write1(out, hdr, b) < 0) {
+ status = EXIT_FAILURE;
+ goto clean;
+ }
+ }
+ bam_destroy1(b);
+ if (ret != -1) // eof
+ status = EXIT_FAILURE;
+ }
+
+ clean:
+ if (hdr != NULL) bam_hdr_destroy(hdr);
+ if (out != NULL && hts_close(out) != 0)
+ status = EXIT_FAILURE;
+ if (hts_close(in) != 0)
+ status = EXIT_FAILURE;
+ return 1;
+}
+
+static int view_vcf(hFILE *hfp, const char *filename)
+{
+ vcfFile *in = hts_hopen(hfp, filename, "r");
+ bcf_hdr_t *hdr = NULL;
+ vcfFile *out = NULL;
+ if (in == NULL) {
+ status = EXIT_FAILURE;
+ return 0;
+ }
+ hdr = bcf_hdr_read(in);
+ if (hdr == NULL) {
+ status = EXIT_FAILURE;
+ goto clean;
+ }
+ out = dup_stdout("w");
+ if (out == NULL) {
+ status = EXIT_FAILURE;
+ goto clean;
+ }
+
+ if (show_headers) {
+ if (bcf_hdr_write(out, hdr) != 0) {
+ status = EXIT_FAILURE;
+ goto clean;
+ }
+ }
+ if (mode == view_all) {
+ bcf1_t *rec = bcf_init();
+ while (bcf_read(in, hdr, rec) >= 0) {
+ if (bcf_write(out, hdr, rec) < 0) {
+ status = EXIT_FAILURE;
+ goto clean;
+ }
+ }
+ bcf_destroy(rec);
+ }
+
+ clean:
+ if (hdr != NULL) bcf_hdr_destroy(hdr);
+ if (out != NULL) hts_close(out);
+ hts_close(in);
+ return 1;
+}
+
+static void usage(FILE *fp, int status)
+{
+ fprintf(fp,
+"Usage: htsfile [-chHv] FILE...\n"
+"Options:\n"
+" -c, --view Write textual form of FILEs to standard output\n"
+" -h, --header-only Display only headers in view mode, not records\n"
+" -H, --no-header Suppress header display in view mode\n"
+" -v, --verbose Increase verbosity of warnings and diagnostics\n");
+ exit(status);
+}
+
+int main(int argc, char **argv)
+{
+ static const struct option options[] = {
+ { "header-only", no_argument, NULL, 'h' },
+ { "no-header", no_argument, NULL, 'H' },
+ { "view", no_argument, NULL, 'c' },
+ { "verbose", no_argument, NULL, 'v' },
+ { "help", no_argument, NULL, '?' },
+ { "version", no_argument, NULL, 1 },
+ { NULL, 0, NULL, 0 }
+ };
+
+ int c, i;
+
+ status = EXIT_SUCCESS;
+ while ((c = getopt_long(argc, argv, "chHv?", options, NULL)) >= 0)
+ switch (c) {
+ case 'c': mode = view_all; break;
+ case 'h': mode = view_headers; show_headers = 1; break;
+ case 'H': show_headers = 0; break;
+ case 'v': hts_verbose++; break;
+ case 1:
+ printf(
+"htsfile (htslib) %s\n"
+"Copyright (C) 2016 Genome Research Ltd.\n",
+ hts_version());
+ exit(EXIT_SUCCESS);
+ break;
+ case '?': usage(stdout, EXIT_SUCCESS); break;
+ default: usage(stderr, EXIT_FAILURE); break;
+ }
+
+ if (optind == argc) usage(stderr, EXIT_FAILURE);
+
+ for (i = optind; i < argc; i++) {
+ htsFormat fmt;
+ hFILE *fp = hopen(argv[i], "r");
+ if (fp == NULL) {
+ fprintf(stderr, "htsfile: can't open \"%s\": %s\n", argv[i], strerror(errno));
+ status = EXIT_FAILURE;
+ continue;
+ }
+
+ if (hts_detect_format(fp, &fmt) < 0) {
+ fprintf(stderr, "htsfile: detecting \"%s\" format failed: %s\n", argv[i], strerror(errno));
+ hclose_abruptly(fp);
+ status = EXIT_FAILURE;
+ continue;
+ }
+
+ if (mode == identify) {
+ char *description = hts_format_description(&fmt);
+ printf("%s:\t%s\n", argv[i], description);
+ free(description);
+ }
+ else
+ switch (fmt.category) {
+ case sequence_data:
+ if (view_sam(fp, argv[i])) fp = NULL;
+ break;
+ case variant_data:
+ if (view_vcf(fp, argv[i])) fp = NULL;
+ break;
+ default:
+ fprintf(stderr, "htsfile: can't view %s: unknown format\n", argv[i]);
+ status = EXIT_FAILURE;
+ break;
+ }
+
+ if (fp && hclose(fp) < 0) {
+ fprintf(stderr, "htsfile: closing %s failed\n", argv[i]);
+ status = EXIT_FAILURE;
+ }
+ }
+
+ return status;
+}
--- /dev/null
+# Makefile rules useful for third-party code using htslib's public API.
+#
+# Copyright (C) 2013-2015 Genome Research Ltd.
+#
+# Author: John Marshall <jm18@sanger.ac.uk>
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in
+# all copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+# DEALINGS IN THE SOFTWARE.
+
+# The makefile fragment included below provides variables that can be used
+# to express dependencies on headers supplied by an in-development htslib.
+# If your source file foo.c #includes <htslib/hts.h> and <htslib/kstring.h>,
+# you can write the correct prerequisites for foo.o as:
+#
+# HTSDIR = <path to htslib top-level directory>
+# include $(HTSDIR)/htslib.mk
+#
+# foo.o: foo.c $(htslib_hts_h) $(htslib_kstring_h)
+
+HTSPREFIX = $(HTSDIR)/
+include $(HTSDIR)/htslib_vars.mk
+
+# Rules for rebuilding an in-development htslib's static and shared libraries.
+# If your program foo links with libhts, adding the appropriate prerequisite
+# will cause the library to be rebuilt as necessary:
+#
+# foo: foo.o $(HTSDIR)/libhts.a
+#
+# or similarly if your target requires any of the tools supplied:
+#
+# bar.bed.bgz.tbi: bar.bed.bgz $(HTSDIR)/tabix
+# $(HTSDIR)/tabix -p bed bar.bed.bgz
+
+HTSLIB_PUBLIC_HEADERS = \
+ $(HTSDIR)/htslib/bgzf.h \
+ $(HTSDIR)/htslib/cram.h \
+ $(HTSDIR)/htslib/faidx.h \
+ $(HTSDIR)/htslib/hfile.h \
+ $(HTSDIR)/htslib/hts.h \
+ $(HTSDIR)/htslib/hts_defs.h \
+ $(HTSDIR)/htslib/kbitset.h \
+ $(HTSDIR)/htslib/kfunc.h \
+ $(HTSDIR)/htslib/khash.h \
+ $(HTSDIR)/htslib/khash_str2int.h \
+ $(HTSDIR)/htslib/klist.h \
+ $(HTSDIR)/htslib/knetfile.h \
+ $(HTSDIR)/htslib/kseq.h \
+ $(HTSDIR)/htslib/ksort.h \
+ $(HTSDIR)/htslib/kstring.h \
+ $(HTSDIR)/htslib/regidx.h \
+ $(HTSDIR)/htslib/sam.h \
+ $(HTSDIR)/htslib/synced_bcf_reader.h \
+ $(HTSDIR)/htslib/tbx.h \
+ $(HTSDIR)/htslib/vcf.h \
+ $(HTSDIR)/htslib/vcf_sweep.h \
+ $(HTSDIR)/htslib/vcfutils.h
+
+HTSLIB_ALL = \
+ $(HTSLIB_PUBLIC_HEADERS) \
+ $(HTSDIR)/bgzf.c \
+ $(HTSDIR)/config.h \
+ $(HTSDIR)/faidx.c \
+ $(HTSDIR)/hfile_internal.h \
+ $(HTSDIR)/hfile.c \
+ $(HTSDIR)/hfile_irods.c \
+ $(HTSDIR)/hfile_libcurl.c \
+ $(HTSDIR)/hfile_net.c \
+ $(HTSDIR)/hts.c \
+ $(HTSDIR)/hts_internal.h \
+ $(HTSDIR)/kfunc.c \
+ $(HTSDIR)/knetfile.c \
+ $(HTSDIR)/kstring.c \
+ $(HTSDIR)/md5.c \
+ $(HTSDIR)/plugin.c \
+ $(HTSDIR)/regidx.c \
+ $(HTSDIR)/sam.c \
+ $(HTSDIR)/synced_bcf_reader.c \
+ $(HTSDIR)/tbx.c \
+ $(HTSDIR)/vcf.c \
+ $(HTSDIR)/vcf_sweep.c \
+ $(HTSDIR)/vcfutils.c \
+ $(HTSDIR)/cram/cram.h \
+ $(HTSDIR)/cram/cram_codecs.c \
+ $(HTSDIR)/cram/cram_codecs.h \
+ $(HTSDIR)/cram/cram_decode.c \
+ $(HTSDIR)/cram/cram_decode.h \
+ $(HTSDIR)/cram/cram_encode.c \
+ $(HTSDIR)/cram/cram_encode.h \
+ $(HTSDIR)/cram/cram_external.c \
+ $(HTSDIR)/cram/cram_index.c \
+ $(HTSDIR)/cram/cram_index.h \
+ $(HTSDIR)/cram/cram_io.c \
+ $(HTSDIR)/cram/cram_io.h \
+ $(HTSDIR)/cram/cram_samtools.c \
+ $(HTSDIR)/cram/cram_samtools.h \
+ $(HTSDIR)/cram/cram_stats.c \
+ $(HTSDIR)/cram/cram_stats.h \
+ $(HTSDIR)/cram/cram_structs.h \
+ $(HTSDIR)/cram/files.c \
+ $(HTSDIR)/cram/mFILE.c \
+ $(HTSDIR)/cram/mFILE.h \
+ $(HTSDIR)/cram/misc.h \
+ $(HTSDIR)/cram/open_trace_file.c \
+ $(HTSDIR)/cram/open_trace_file.h \
+ $(HTSDIR)/cram/os.h \
+ $(HTSDIR)/cram/pooled_alloc.c \
+ $(HTSDIR)/cram/pooled_alloc.h \
+ $(HTSDIR)/cram/rANS_byte.h \
+ $(HTSDIR)/cram/rANS_static.c \
+ $(HTSDIR)/cram/rANS_static.h \
+ $(HTSDIR)/cram/sam_header.c \
+ $(HTSDIR)/cram/sam_header.h \
+ $(HTSDIR)/cram/string_alloc.c \
+ $(HTSDIR)/cram/string_alloc.h \
+ $(HTSDIR)/cram/thread_pool.c \
+ $(HTSDIR)/cram/thread_pool.h \
+ $(HTSDIR)/cram/vlen.c \
+ $(HTSDIR)/cram/vlen.h \
+ $(HTSDIR)/cram/zfio.c \
+ $(HTSDIR)/cram/zfio.h
+
+$(HTSDIR)/config.h:
+ +cd $(HTSDIR) && $(MAKE) config.h
+
+$(HTSDIR)/libhts.a: $(HTSLIB_ALL)
+ +cd $(HTSDIR) && $(MAKE) lib-static
+
+$(HTSDIR)/libhts.so $(HTSDIR)/libhts.dylib: $(HTSLIB_ALL)
+ +cd $(HTSDIR) && $(MAKE) lib-shared
+
+$(HTSDIR)/bgzip: $(HTSDIR)/bgzip.c $(HTSLIB_PUBLIC_HEADERS)
+ +cd $(HTSDIR) && $(MAKE) bgzip
+
+$(HTSDIR)/htsfile: $(HTSDIR)/htsfile.c $(HTSLIB_PUBLIC_HEADERS)
+ +cd $(HTSDIR) && $(MAKE) htsfile
+
+$(HTSDIR)/tabix: $(HTSDIR)/tabix.c $(HTSLIB_PUBLIC_HEADERS)
+ +cd $(HTSDIR) && $(MAKE) tabix
+
+# Rules for phony targets. You may wish to have your corresponding phony
+# targets invoke these in addition to their own recipes:
+#
+# clean: clean-htslib
+
+all-htslib clean-htslib install-htslib plugins-htslib:
+ +cd $(HTSDIR) && $(MAKE) $(@:-htslib=)
+
+.PHONY: all-htslib clean-htslib install-htslib plugins-htslib
--- /dev/null
+includedir=@includedir@
+libdir=@libdir@
+
+Name: htslib
+Description: C library for high-throughput sequencing data formats
+Version: @PACKAGE_VERSION@
+Cflags: -I${includedir}
+Libs: -L${libdir} -lhts
+Libs.private: -L${libdir} -lhts -lm -lpthread
+Requires.private: zlib
--- /dev/null
+/* The MIT License
+
+ Copyright (c) 2008 Broad Institute / Massachusetts Institute of Technology
+ 2011, 2012 Attractive Chaos <attractor@live.co.uk>
+ Copyright (C) 2009, 2013, 2014 Genome Research Ltd
+
+ Permission is hereby granted, free of charge, to any person obtaining a copy
+ of this software and associated documentation files (the "Software"), to deal
+ in the Software without restriction, including without limitation the rights
+ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+ copies of the Software, and to permit persons to whom the Software is
+ furnished to do so, subject to the following conditions:
+
+ The above copyright notice and this permission notice shall be included in
+ all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+ IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+ FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+ AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+ LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+ OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
+ THE SOFTWARE.
+*/
+
+/* The BGZF library was originally written by Bob Handsaker from the Broad
+ * Institute. It was later improved by the SAMtools developers. */
+
+#ifndef HTSLIB_BGZF_H
+#define HTSLIB_BGZF_H
+
+#include <stdint.h>
+#include <stdio.h>
+#include <zlib.h>
+#include <sys/types.h>
+
+#include "hts_defs.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+#define BGZF_BLOCK_SIZE 0xff00 // make sure compressBound(BGZF_BLOCK_SIZE) < BGZF_MAX_BLOCK_SIZE
+#define BGZF_MAX_BLOCK_SIZE 0x10000
+
+#define BGZF_ERR_ZLIB 1
+#define BGZF_ERR_HEADER 2
+#define BGZF_ERR_IO 4
+#define BGZF_ERR_MISUSE 8
+
+struct hFILE;
+struct bgzf_mtaux_t;
+typedef struct __bgzidx_t bgzidx_t;
+
+struct BGZF {
+ unsigned errcode:16, is_write:2, is_be:2;
+ signed compress_level:9;
+ unsigned is_compressed:2, is_gzip:1;
+ int cache_size;
+ int block_length, block_offset;
+ int64_t block_address, uncompressed_address;
+ void *uncompressed_block, *compressed_block;
+ void *cache; // a pointer to a hash table
+ struct hFILE *fp; // actual file handle
+ struct bgzf_mtaux_t *mt; // only used for multi-threading
+ bgzidx_t *idx; // BGZF index
+ int idx_build_otf; // build index on the fly, set by bgzf_index_build_init()
+ z_stream *gz_stream;// for gzip-compressed files
+};
+#ifndef HTS_BGZF_TYPEDEF
+typedef struct BGZF BGZF;
+#define HTS_BGZF_TYPEDEF
+#endif
+
+#ifndef KSTRING_T
+#define KSTRING_T kstring_t
+typedef struct __kstring_t {
+ size_t l, m;
+ char *s;
+} kstring_t;
+#endif
+
+ /******************
+ * Basic routines *
+ ******************/
+
+ /**
+ * Open an existing file descriptor for reading or writing.
+ *
+ * @param fd file descriptor
+ * @param mode mode matching /[rwag][u0-9]+/: 'r' for reading, 'w' for
+ * writing, 'a' for appending, 'g' for gzip rather than BGZF
+ * compression (with 'w' only), and digit specifies the zlib
+ * compression level.
+ * Note that there is a distinction between 'u' and '0': the
+ * first yields plain uncompressed output whereas the latter
+ * outputs uncompressed data wrapped in the zlib format.
+ * @return BGZF file handler; 0 on error
+ */
+ BGZF* bgzf_dopen(int fd, const char *mode);
+
+ #define bgzf_fdopen(fd, mode) bgzf_dopen((fd), (mode)) // for backward compatibility
+
+ /**
+ * Open the specified file for reading or writing.
+ */
+ BGZF* bgzf_open(const char* path, const char *mode);
+
+ /**
+ * Open an existing hFILE stream for reading or writing.
+ */
+ BGZF* bgzf_hopen(struct hFILE *fp, const char *mode);
+
+ /**
+ * Close the BGZF and free all associated resources.
+ *
+ * @param fp BGZF file handler
+ * @return 0 on success and -1 on error
+ */
+ int bgzf_close(BGZF *fp);
+
+ /**
+ * Read up to _length_ bytes from the file storing into _data_.
+ *
+ * @param fp BGZF file handler
+ * @param data data array to read into
+ * @param length size of data to read
+ * @return number of bytes actually read; 0 on end-of-file and -1 on error
+ */
+ ssize_t bgzf_read(BGZF *fp, void *data, size_t length) HTS_RESULT_USED;
+
+ /**
+ * Write _length_ bytes from _data_ to the file. If no I/O errors occur,
+ * the complete _length_ bytes will be written (or queued for writing).
+ *
+ * @param fp BGZF file handler
+ * @param data data array to write
+ * @param length size of data to write
+ * @return number of bytes written (i.e., _length_); negative on error
+ */
+ ssize_t bgzf_write(BGZF *fp, const void *data, size_t length) HTS_RESULT_USED;
+
+ /**
+ * Read up to _length_ bytes directly from the underlying stream without
+ * decompressing. Bypasses BGZF blocking, so must be used with care in
+ * specialised circumstances only.
+ *
+ * @param fp BGZF file handler
+ * @param data data array to read into
+ * @param length number of raw bytes to read
+ * @return number of bytes actually read; 0 on end-of-file and -1 on error
+ */
+ ssize_t bgzf_raw_read(BGZF *fp, void *data, size_t length) HTS_RESULT_USED;
+
+ /**
+ * Write _length_ bytes directly to the underlying stream without
+ * compressing. Bypasses BGZF blocking, so must be used with care
+ * in specialised circumstances only.
+ *
+ * @param fp BGZF file handler
+ * @param data data array to write
+ * @param length number of raw bytes to write
+ * @return number of bytes actually written; -1 on error
+ */
+ ssize_t bgzf_raw_write(BGZF *fp, const void *data, size_t length) HTS_RESULT_USED;
+
+ /**
+ * Write the data in the buffer to the file.
+ *
+ * @param fp BGZF file handle
+ * @return 0 on success and -1 on error
+ */
+ int bgzf_flush(BGZF *fp) HTS_RESULT_USED;
+
+ /**
+ * Return a virtual file pointer to the current location in the file.
+ * No interpetation of the value should be made, other than a subsequent
+ * call to bgzf_seek can be used to position the file at the same point.
+ * Return value is non-negative on success.
+ */
+ #define bgzf_tell(fp) (((fp)->block_address << 16) | ((fp)->block_offset & 0xFFFF))
+
+ /**
+ * Set the file to read from the location specified by _pos_.
+ *
+ * @param fp BGZF file handler
+ * @param pos virtual file offset returned by bgzf_tell()
+ * @param whence must be SEEK_SET
+ * @return 0 on success and -1 on error
+ */
+ int64_t bgzf_seek(BGZF *fp, int64_t pos, int whence) HTS_RESULT_USED;
+
+ /**
+ * Check if the BGZF end-of-file (EOF) marker is present
+ *
+ * @param fp BGZF file handler opened for reading
+ * @return 1 if the EOF marker is present and correct;
+ * 2 if it can't be checked, e.g., because fp isn't seekable;
+ * 0 if the EOF marker is absent;
+ * -1 (with errno set) on error
+ */
+ int bgzf_check_EOF(BGZF *fp);
+
+ /**
+ * Check if a file is in the BGZF format
+ *
+ * @param fn file name
+ * @return 1 if _fn_ is BGZF; 0 if not or on I/O error
+ */
+ int bgzf_is_bgzf(const char *fn);
+
+ /*********************
+ * Advanced routines *
+ *********************/
+
+ /**
+ * Set the cache size. Only effective when compiled with -DBGZF_CACHE.
+ *
+ * @param fp BGZF file handler
+ * @param size size of cache in bytes; 0 to disable caching (default)
+ */
+ void bgzf_set_cache_size(BGZF *fp, int size);
+
+ /**
+ * Flush the file if the remaining buffer size is smaller than _size_
+ * @return 0 if flushing succeeded or was not needed; negative on error
+ */
+ int bgzf_flush_try(BGZF *fp, ssize_t size) HTS_RESULT_USED;
+
+ /**
+ * Read one byte from a BGZF file. It is faster than bgzf_read()
+ * @param fp BGZF file handler
+ * @return byte read; -1 on end-of-file or error
+ */
+ int bgzf_getc(BGZF *fp);
+
+ /**
+ * Read one line from a BGZF file. It is faster than bgzf_getc()
+ *
+ * @param fp BGZF file handler
+ * @param delim delimitor
+ * @param str string to write to; must be initialized
+ * @return length of the string; 0 on end-of-file; negative on error
+ */
+ int bgzf_getline(BGZF *fp, int delim, kstring_t *str);
+
+ /**
+ * Read the next BGZF block.
+ */
+ int bgzf_read_block(BGZF *fp) HTS_RESULT_USED;
+
+ /**
+ * Enable multi-threading (only effective on writing and when the
+ * library was compiled with -DBGZF_MT)
+ *
+ * @param fp BGZF file handler; must be opened for writing
+ * @param n_threads #threads used for writing
+ * @param n_sub_blks #blocks processed by each thread; a value 64-256 is recommended
+ */
+ int bgzf_mt(BGZF *fp, int n_threads, int n_sub_blks);
+
+ /**
+ * Compress a single BGZF block.
+ *
+ * @param dst output buffer (must have size >= BGZF_MAX_BLOCK_SIZE)
+ * @param dlen size of output buffer; updated on return to the number
+ * of bytes actually written to dst
+ * @param src buffer to be compressed
+ * @param slen size of data to compress (must be <= BGZF_BLOCK_SIZE)
+ * @param level compression level
+ * @return 0 on success and negative on error
+ */
+ int bgzf_compress(void *dst, size_t *dlen, const void *src, size_t slen, int level);
+
+ /*******************
+ * bgzidx routines *
+ *******************/
+
+ /**
+ * Position BGZF at the uncompressed offset
+ *
+ * @param fp BGZF file handler; must be opened for reading
+ * @param uoffset file offset in the uncompressed data
+ * @param where SEEK_SET supported atm
+ *
+ * Returns 0 on success and -1 on error.
+ */
+ int bgzf_useek(BGZF *fp, long uoffset, int where) HTS_RESULT_USED;
+
+ /**
+ * Position in uncompressed BGZF
+ *
+ * @param fp BGZF file handler; must be opened for reading
+ *
+ * Returns the current offset on success and -1 on error.
+ */
+ long bgzf_utell(BGZF *fp);
+
+ /**
+ * Tell BGZF to build index while compressing.
+ *
+ * @param fp BGZF file handler; can be opened for reading or writing.
+ *
+ * Returns 0 on success and -1 on error.
+ */
+ int bgzf_index_build_init(BGZF *fp);
+
+ /**
+ * Load BGZF index
+ *
+ * @param fp BGZF file handler
+ * @param bname base name
+ * @param suffix suffix to add to bname (can be NULL)
+ *
+ * Returns 0 on success and -1 on error.
+ */
+ int bgzf_index_load(BGZF *fp, const char *bname, const char *suffix);
+
+ /**
+ * Save BGZF index
+ *
+ * @param fp BGZF file handler
+ * @param bname base name
+ * @param suffix suffix to add to bname (can be NULL)
+ *
+ * Returns 0 on success and -1 on error.
+ */
+ int bgzf_index_dump(BGZF *fp,
+ const char *bname, const char *suffix) HTS_RESULT_USED;
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* cram.h -- public CRAM-specific API functions.
+
+ Copyright (C) 2015 Genome Research Ltd.
+
+ Author: James Bonfield <jkb@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+/*! \file
+ * CRAM interface.
+ *
+ * Consider using the higher level hts_*() API for programs that wish to
+ * be file format agnostic (see htslib/hts.h).
+ *
+ * This API should be used for CRAM specific code. The specifics of the
+ * public API are implemented in cram_io.h, cram_encode.h and cram_decode.h
+ * although these should not be included directly (use this file instead).
+ */
+
+#ifndef HTSLIB_CRAM_H
+#define HTSLIB_CRAM_H
+
+#include <stdarg.h>
+#include <stdint.h>
+#include <sys/types.h>
+
+#include "hts.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+#ifndef _CRAM_STRUCTS_H_
+enum cram_block_method {
+ ERROR = -1,
+ RAW = 0,
+ GZIP = 1,
+ BZIP2 = 2,
+ LZMA = 3,
+ RANS = 4, // Generic; either order
+ RANS0 = 4,
+ RANS1 = 10, // Not externalised; stored as RANS (generic)
+ GZIP_RLE = 11, // NB: not externalised in CRAM
+};
+
+enum cram_content_type {
+ CT_ERROR = -1,
+ FILE_HEADER = 0,
+ COMPRESSION_HEADER = 1,
+ MAPPED_SLICE = 2,
+ UNMAPPED_SLICE = 3, // CRAM V1.0 only
+ EXTERNAL = 4,
+ CORE = 5,
+};
+
+// Opaque data types, see cram_structs for the fully fledged versions.
+typedef struct SAM_hdr SAM_hdr;
+typedef struct cram_file_def cram_file_def;
+typedef struct cram_fd cram_fd;
+typedef struct cram_container cram_container;
+typedef struct cram_block cram_block;
+typedef struct cram_slice cram_slice;
+typedef struct cram_metrics cram_metrics;
+typedef struct cram_block_slice_hdr cram_block_slice_hdr;
+typedef struct cram_block_compression_hdr cram_block_compression_hdr;
+typedef struct refs_t refs_t; // need this?
+
+struct hFILE;
+#endif
+
+// Accessor functions
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_fd
+ */
+SAM_hdr *cram_fd_get_header(cram_fd *fd);
+void cram_fd_set_header(cram_fd *fd, SAM_hdr *hdr);
+
+int cram_fd_get_version(cram_fd *fd);
+void cram_fd_set_version(cram_fd *fd, int vers);
+
+int cram_major_vers(cram_fd *fd);
+int cram_minor_vers(cram_fd *fd);
+
+struct hFILE *cram_fd_get_fp(cram_fd *fd);
+void cram_fd_set_fp(cram_fd *fd, struct hFILE *fp);
+
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_container
+ */
+int32_t cram_container_get_length(cram_container *c);
+void cram_container_set_length(cram_container *c, int32_t length);
+int32_t cram_container_get_num_blocks(cram_container *c);
+void cram_container_set_num_blocks(cram_container *c, int32_t num_blocks);
+int32_t *cram_container_get_landmarks(cram_container *c, int32_t *num_landmarks);
+void cram_container_set_landmarks(cram_container *c, int32_t num_landmarks,
+ int32_t *landmarks);
+
+/* Returns true if the container is empty (EOF marker) */
+int cram_container_is_empty(cram_fd *fd);
+
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_block
+ */
+int32_t cram_block_get_content_id(cram_block *b);
+int32_t cram_block_get_comp_size(cram_block *b);
+int32_t cram_block_get_uncomp_size(cram_block *b);
+int32_t cram_block_get_crc32(cram_block *b);
+void * cram_block_get_data(cram_block *b);
+
+enum cram_content_type cram_block_get_content_type(cram_block *b);
+
+void cram_block_set_content_id(cram_block *b, int32_t id);
+void cram_block_set_comp_size(cram_block *b, int32_t size);
+void cram_block_set_uncomp_size(cram_block *b, int32_t size);
+void cram_block_set_crc32(cram_block *b, int32_t crc);
+void cram_block_set_data(cram_block *b, void *data);
+
+int cram_block_append(cram_block *b, void *data, int size);
+void cram_block_update_size(cram_block *b);
+
+// Offset is known as "size" internally, but it can be confusing.
+size_t cram_block_get_offset(cram_block *b);
+void cram_block_set_offset(cram_block *b, size_t offset);
+
+/*
+ * Computes the size of a cram block, including the block
+ * header itself.
+ */
+uint32_t cram_block_size(cram_block *b);
+
+/*
+ * Renumbers RG numbers in a cram compression header.
+ *
+ * CRAM stores RG as the Nth number in the header, rather than a
+ * string holding the ID: tag. This is smaller in space, but means
+ * "samtools cat" to join files together that contain single but
+ * different RG lines needs a way of renumbering them.
+ *
+ * The file descriptor is expected to be immediately after the
+ * cram_container structure (ie before the cram compression header).
+ * Due to the nature of the CRAM format, this needs to read and write
+ * the blocks itself. Note that there may be multiple slices within
+ * the container, meaning multiple compression headers to manipulate.
+ * Changing RG may change the size of the compression header and
+ * therefore the length field in the container. Hence we rewrite all
+ * blocks just incase and also emit the adjusted container.
+ *
+ * The current implementation can only cope with renumbering a single
+ * RG (and only then if it is using HUFFMAN or BETA codecs). In
+ * theory it *may* be possible to renumber multiple RGs if they use
+ * HUFFMAN to the CORE block or use an external block unshared by any
+ * other data series. So we have an API that can be upgraded to
+ * support this, but do not implement it for now. An example
+ * implementation of RG as an EXTERNAL block would be to find that
+ * block and rewrite it, returning the number of blocks consumed.
+ *
+ * Returns 0 on success;
+ * -1 if unable to edit;
+ * -2 on other errors (eg I/O).
+ */
+int cram_transcode_rg(cram_fd *in, cram_fd *out,
+ cram_container *c,
+ int nrg, int *in_rg, int *out_rg);
+
+/*
+ * Copies the blocks representing the next num_slice slices from a
+ * container from 'in' to 'out'. It is expected that the file pointer
+ * is just after the read of the cram_container and cram compression
+ * header.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_copy_slice(cram_fd *in, cram_fd *out, int32_t num_slice);
+
+/*
+ *-----------------------------------------------------------------------------
+ * SAM_hdr
+ */
+
+/*! Tokenises a SAM header into a hash table.
+ *
+ * Also extracts a few bits on specific data types, such as @RG lines.
+ *
+ * @return
+ * Returns a SAM_hdr struct on success (free with sam_hdr_free());
+ * NULL on failure
+ */
+SAM_hdr *sam_hdr_parse_(const char *hdr, int len);
+
+
+/*
+ *-----------------------------------------------------------------------------
+ * cram_io basics
+ */
+
+/**@{ ----------------------------------------------------------------------
+ * CRAM blocks - the dynamically growable data block. We have code to
+ * create, update, (un)compress and read/write.
+ *
+ * These are derived from the deflate_interlaced.c blocks, but with the
+ * CRAM extension of content types and IDs.
+ */
+
+/*! Allocates a new cram_block structure with a specified content_type and
+ * id.
+ *
+ * @return
+ * Returns block pointer on success;
+ * NULL on failure
+ */
+cram_block *cram_new_block(enum cram_content_type content_type,
+ int content_id);
+
+/*! Reads a block from a cram file.
+ *
+ * @return
+ * Returns cram_block pointer on success;
+ * NULL on failure
+ */
+cram_block *cram_read_block(cram_fd *fd);
+
+/*! Writes a CRAM block.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_write_block(cram_fd *fd, cram_block *b);
+
+/*! Frees a CRAM block, deallocating internal data too.
+ */
+void cram_free_block(cram_block *b);
+
+/*! Uncompresses a CRAM block, if compressed.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_uncompress_block(cram_block *b);
+
+/*! Compresses a block.
+ *
+ * Compresses a block using one of two different zlib strategies. If we only
+ * want one choice set strat2 to be -1.
+ *
+ * The logic here is that sometimes Z_RLE does a better job than Z_FILTERED
+ * or Z_DEFAULT_STRATEGY on quality data. If so, we'd rather use it as it is
+ * significantly faster.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_compress_block(cram_fd *fd, cram_block *b, cram_metrics *metrics,
+ int method, int level);
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * Containers
+ */
+
+/*! Creates a new container, specifying the maximum number of slices
+ * and records permitted.
+ *
+ * @return
+ * Returns cram_container ptr on success;
+ * NULL on failure
+ */
+cram_container *cram_new_container(int nrec, int nslice);
+void cram_free_container(cram_container *c);
+
+/*! Reads a container header.
+ *
+ * @return
+ * Returns cram_container on success;
+ * NULL on failure or no container left (fd->err == 0).
+ */
+cram_container *cram_read_container(cram_fd *fd);
+
+/*! Writes a container structure.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_write_container(cram_fd *fd, cram_container *h);
+
+/*
+ * Stores the container structure in dat and returns *size as the
+ * number of bytes written to dat[]. The input size of dat is also
+ * held in *size and should be initialised to cram_container_size(c).
+ *
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_store_container(cram_fd *fd, cram_container *c, char *dat, int *size);
+
+int cram_container_size(cram_container *c);
+
+/**@}*/
+/**@{ ----------------------------------------------------------------------
+ * The top-level cram opening, closing and option handling
+ */
+
+/*! Opens a CRAM file for read (mode "rb") or write ("wb").
+ *
+ * The filename may be "-" to indicate stdin or stdout.
+ *
+ * @return
+ * Returns file handle on success;
+ * NULL on failure.
+ */
+cram_fd *cram_open(const char *filename, const char *mode);
+
+/*! Opens an existing stream for reading or writing.
+ *
+ * @return
+ * Returns file handle on success;
+ * NULL on failure.
+ */
+cram_fd *cram_dopen(struct hFILE *fp, const char *filename, const char *mode);
+
+/*! Closes a CRAM file.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_close(cram_fd *fd);
+
+/*
+ * Seek within a CRAM file.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_seek(cram_fd *fd, off_t offset, int whence);
+
+/*
+ * Flushes a CRAM file.
+ * Useful for when writing to stdout without wishing to close the stream.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int cram_flush(cram_fd *fd);
+
+/*! Checks for end of file on a cram_fd stream.
+ *
+ * @return
+ * Returns 0 if not at end of file
+ * 1 if we hit an expected EOF (end of range or EOF block)
+ * 2 for other EOF (end of stream without EOF block)
+ */
+int cram_eof(cram_fd *fd);
+
+/*! Sets options on the cram_fd.
+ *
+ * See CRAM_OPT_* definitions in hts.h.
+ * Use this immediately after opening.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_set_option(cram_fd *fd, enum hts_fmt_option opt, ...);
+
+/*! Sets options on the cram_fd.
+ *
+ * See CRAM_OPT_* definitions in hts.h.
+ * Use this immediately after opening.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_set_voption(cram_fd *fd, enum hts_fmt_option opt, va_list args);
+
+/*!
+ * Attaches a header to a cram_fd.
+ *
+ * This should be used when creating a new cram_fd for writing where
+ * we have an SAM_hdr already constructed (eg from a file we've read
+ * in).
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int cram_set_header(cram_fd *fd, SAM_hdr *hdr);
+
+
+/* As int32_decoded/encode, but from/to blocks instead of cram_fd */
+int int32_put_blk(cram_block *b, int32_t val);
+
+/**@}*/
+/**@{ -------------------------------------------------------------------*/
+/*! Deallocates all storage used by a SAM_hdr struct.
+ *
+ * This also decrements the header reference count. If after decrementing
+ * it is still non-zero then the header is assumed to be in use by another
+ * caller and the free is not done.
+ *
+ * This is a synonym for sam_hdr_dec_ref().
+ */
+void sam_hdr_free(SAM_hdr *hdr);
+
+/*! Returns the current length of the SAM_hdr in text form.
+ *
+ * Call sam_hdr_rebuild() first if editing has taken place.
+ */
+int sam_hdr_length(SAM_hdr *hdr);
+
+/*! Returns the string form of the SAM_hdr.
+ *
+ * Call sam_hdr_rebuild() first if editing has taken place.
+ */
+char *sam_hdr_str(SAM_hdr *hdr);
+
+/*! Appends a formatted line to an existing SAM header.
+ *
+ * Line is a full SAM header record, eg "@SQ\tSN:foo\tLN:100", with
+ * optional new-line. If it contains more than 1 line then multiple lines
+ * will be added in order.
+ *
+ * Len is the length of the text data, or 0 if unknown (in which case
+ * it should be null terminated).
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+
+/*! Add an @PG line.
+ *
+ * If we wish complete control over this use sam_hdr_add() directly. This
+ * function uses that, but attempts to do a lot of tedious house work for
+ * you too.
+ *
+ * - It will generate a suitable ID if the supplied one clashes.
+ * - It will generate multiple @PG records if we have multiple PG chains.
+ *
+ * Call it as per sam_hdr_add() with a series of key,value pairs ending
+ * in NULL.
+ *
+ * @return
+ * Returns 0 on success;
+ * -1 on failure
+ */
+int sam_hdr_add_PG(SAM_hdr *sh, const char *name, ...);
+
+/*!
+ * A function to help with construction of CL tags in @PG records.
+ * Takes an argc, argv pair and returns a single space-separated string.
+ * This string should be deallocated by the calling function.
+ *
+ * @return
+ * Returns malloced char * on success;
+ * NULL on failure
+ */
+char *stringify_argv(int argc, char *argv[]);
+/**@}*/
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* faidx.h -- FASTA random access.
+
+ Copyright (C) 2008, 2009, 2013, 2014 Genome Research Ltd.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+#ifndef HTSLIB_FAIDX_H
+#define HTSLIB_FAIDX_H
+
+#include "hts_defs.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*!
+ @header
+
+ Index FASTA files and extract subsequence.
+
+ The fai file index columns are:
+ - chromosome name
+ - chromosome length: number of bases
+ - offset: number of bytes to skip to get to the first base
+ from the beginning of the file, including the length
+ of the sequence description string (">chr ..\n")
+ - line length: number of bases per line (excluding \n)
+ - binary line length: number of bytes, including \n
+
+ @copyright The Wellcome Trust Sanger Institute.
+ */
+
+struct __faidx_t;
+typedef struct __faidx_t faidx_t;
+
+ /*!
+ @abstract Build index for a FASTA or bgzip-compressed FASTA file.
+ @param fn FASTA file name
+ @return 0 on success; or -1 on failure
+ @discussion File "fn.fai" will be generated.
+ */
+ int fai_build(const char *fn) HTS_RESULT_USED;
+
+ /*!
+ @abstract Destroy a faidx_t struct.
+ @param fai Pointer to the struct to be destroyed
+ */
+ void fai_destroy(faidx_t *fai);
+
+ /*!
+ @abstract Load index from "fn.fai".
+ @param fn File name of the FASTA file
+ */
+ faidx_t *fai_load(const char *fn);
+
+ /*!
+ @abstract Fetch the sequence in a region.
+ @param fai Pointer to the faidx_t struct
+ @param reg Region in the format "chr2:20,000-30,000"
+ @param len Length of the region; -2 if seq not present, -1 general error
+ @return Pointer to the sequence; null on failure
+
+ @discussion The returned sequence is allocated by malloc family
+ and should be destroyed by end users by calling free() on it.
+ */
+ char *fai_fetch(const faidx_t *fai, const char *reg, int *len);
+
+ /*!
+ @abstract Fetch the number of sequences.
+ @param fai Pointer to the faidx_t struct
+ @return The number of sequences
+ */
+ int faidx_fetch_nseq(const faidx_t *fai) HTS_DEPRECATED("Please use faidx_nseq instead");
+
+ /*!
+ @abstract Fetch the sequence in a region.
+ @param fai Pointer to the faidx_t struct
+ @param c_name Region name
+ @param p_beg_i Beginning position number (zero-based)
+ @param p_end_i End position number (zero-based)
+ @param len Length of the region; -2 if c_name not present, -1 general error
+ @return Pointer to the sequence; null on failure
+
+ @discussion The returned sequence is allocated by malloc family
+ and should be destroyed by end users by calling free() on it.
+ */
+ char *faidx_fetch_seq(const faidx_t *fai, const char *c_name, int p_beg_i, int p_end_i, int *len);
+
+ /*!
+ @abstract Query if sequence is present
+ @param fai Pointer to the faidx_t struct
+ @param seq Sequence name
+ @return 1 if present or 0 if absent
+ */
+ int faidx_has_seq(const faidx_t *fai, const char *seq);
+
+ /*!
+ @abstract Return number of sequences in fai index
+ */
+ int faidx_nseq(const faidx_t *fai);
+
+ /*!
+ @abstract Return name of i-th sequence
+ */
+ const char *faidx_iseq(const faidx_t *fai, int i);
+
+ /*!
+ @abstract Return sequence length, -1 if not present
+ */
+ int faidx_seq_len(const faidx_t *fai, const char *seq);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* hfile.h -- buffered low-level input/output streams.
+
+ Copyright (C) 2013-2015 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_HFILE_H
+#define HTSLIB_HFILE_H
+
+#include <string.h>
+
+#include <sys/types.h>
+
+#include "hts_defs.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/* These fields are declared here solely for the benefit of the inline functions
+ below. They may change in future releases. User code should not use them
+ directly; you should imagine that hFILE is an opaque incomplete type. */
+struct hFILE_backend;
+typedef struct hFILE {
+ char *buffer, *begin, *end, *limit;
+ const struct hFILE_backend *backend;
+ off_t offset;
+ unsigned at_eof:1;
+ int has_errno;
+} hFILE;
+
+/*!
+ @abstract Open the named file or URL as a stream
+ @return An hFILE pointer, or NULL (with errno set) if an error occurred.
+ @notes The usual @c fopen(3) @a mode letters are supported: one of
+ @e r (read), @e w (write), @e a (append), optionally followed by any of
+ @e + (update), @e e (close on @c exec(2)), @e x (create exclusively).
+*/
+hFILE *hopen(const char *filename, const char *mode) HTS_RESULT_USED;
+
+/*!
+ @abstract Associate a stream with an existing open file descriptor
+ @return An hFILE pointer, or NULL (with errno set) if an error occurred.
+ @notes For socket descriptors (on Windows), mode should contain 's'.
+*/
+hFILE *hdopen(int fd, const char *mode) HTS_RESULT_USED;
+
+/*!
+ @abstract Report whether the file name or URL denotes remote storage
+ @return 0 if local, 1 if remote.
+ @notes "Remote" means involving e.g. explicit network access, with the
+ implication that callers may wish to cache such files' contents locally.
+*/
+int hisremote(const char *filename) HTS_RESULT_USED;
+
+/*!
+ @abstract Flush (for output streams) and close the stream
+ @return 0 if successful, or EOF (with errno set) if an error occurred.
+*/
+int hclose(hFILE *fp) HTS_RESULT_USED;
+
+/*!
+ @abstract Close the stream, without flushing or propagating errors
+ @notes For use while cleaning up after an error only. Preserves errno.
+*/
+void hclose_abruptly(hFILE *fp);
+
+/*!
+ @abstract Return the stream's error indicator
+ @return Non-zero (in fact, an errno value) if an error has occurred.
+ @notes This would be called herror() and return true/false to parallel
+ ferror(3), but a networking-related herror(3) function already exists. */
+static inline int herrno(hFILE *fp)
+{
+ return fp->has_errno;
+}
+
+/*!
+ @abstract Clear the stream's error indicator
+*/
+static inline void hclearerr(hFILE *fp)
+{
+ fp->has_errno = 0;
+}
+
+/*!
+ @abstract Reposition the read/write stream offset
+ @return The resulting offset within the stream (as per lseek(2)),
+ or negative if an error occurred.
+*/
+off_t hseek(hFILE *fp, off_t offset, int whence) HTS_RESULT_USED;
+
+/*!
+ @abstract Report the current stream offset
+ @return The offset within the stream, starting from zero.
+*/
+static inline off_t htell(hFILE *fp)
+{
+ return fp->offset + (fp->begin - fp->buffer);
+}
+
+/*!
+ @abstract Read one character from the stream
+ @return The character read, or EOF on end-of-file or error
+*/
+static inline int hgetc(hFILE *fp)
+{
+ extern int hgetc2(hFILE *);
+ return (fp->end > fp->begin)? (unsigned char) *(fp->begin++) : hgetc2(fp);
+}
+
+/*!
+ @abstract Peek at characters to be read without removing them from buffers
+ @param fp The file stream
+ @param buffer The buffer to which the peeked bytes will be written
+ @param nbytes The number of bytes to peek at; limited by the size of the
+ internal buffer, which could be as small as 4K.
+ @return The number of bytes peeked, which may be less than nbytes if EOF
+ is encountered; or negative, if there was an I/O error.
+ @notes The characters peeked at remain in the stream's internal buffer,
+ and will be returned by later hread() etc calls.
+*/
+ssize_t hpeek(hFILE *fp, void *buffer, size_t nbytes) HTS_RESULT_USED;
+
+/*!
+ @abstract Read a block of characters from the file
+ @return The number of bytes read, or negative if an error occurred.
+ @notes The full nbytes requested will be returned, except as limited
+ by EOF or I/O errors.
+*/
+static inline ssize_t HTS_RESULT_USED
+hread(hFILE *fp, void *buffer, size_t nbytes)
+{
+ extern ssize_t hread2(hFILE *, void *, size_t, size_t);
+
+ size_t n = fp->end - fp->begin;
+ if (n > nbytes) n = nbytes;
+ memcpy(buffer, fp->begin, n);
+ fp->begin += n;
+ return (n == nbytes)? (ssize_t) n : hread2(fp, buffer, nbytes, n);
+}
+
+/*!
+ @abstract Write a character to the stream
+ @return The character written, or EOF if an error occurred.
+*/
+static inline int hputc(int c, hFILE *fp)
+{
+ extern int hputc2(int, hFILE *);
+ if (fp->begin < fp->limit) *(fp->begin++) = c;
+ else c = hputc2(c, fp);
+ return c;
+}
+
+/*!
+ @abstract Write a string to the stream
+ @return 0 if successful, or EOF if an error occurred.
+*/
+static inline int hputs(const char *text, hFILE *fp)
+{
+ extern int hputs2(const char *, size_t, size_t, hFILE *);
+
+ size_t nbytes = strlen(text), n = fp->limit - fp->begin;
+ if (n > nbytes) n = nbytes;
+ memcpy(fp->begin, text, n);
+ fp->begin += n;
+ return (n == nbytes)? 0 : hputs2(text, nbytes, n, fp);
+}
+
+/*!
+ @abstract Write a block of characters to the file
+ @return Either nbytes, or negative if an error occurred.
+ @notes In the absence of I/O errors, the full nbytes will be written.
+*/
+static inline ssize_t HTS_RESULT_USED
+hwrite(hFILE *fp, const void *buffer, size_t nbytes)
+{
+ extern ssize_t hwrite2(hFILE *, const void *, size_t, size_t);
+
+ size_t n = fp->limit - fp->begin;
+ if (n > nbytes) n = nbytes;
+ memcpy(fp->begin, buffer, n);
+ fp->begin += n;
+ return (n==nbytes)? (ssize_t) n : hwrite2(fp, buffer, nbytes, n);
+}
+
+/*!
+ @abstract For writing streams, flush buffered output to the underlying stream
+ @return 0 if successful, or EOF if an error occurred.
+*/
+int hflush(hFILE *fp) HTS_RESULT_USED;
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* hts.h -- format-neutral I/O, indexing, and iterator API functions.
+
+ Copyright (C) 2012-2015 Genome Research Ltd.
+ Copyright (C) 2012 Broad Institute.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_HTS_H
+#define HTSLIB_HTS_H
+
+#include <stddef.h>
+#include <stdint.h>
+
+#include "hts_defs.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+#ifndef HTS_BGZF_TYPEDEF
+typedef struct BGZF BGZF;
+#define HTS_BGZF_TYPEDEF
+#endif
+struct cram_fd;
+struct hFILE;
+
+#ifndef KSTRING_T
+#define KSTRING_T kstring_t
+typedef struct __kstring_t {
+ size_t l, m;
+ char *s;
+} kstring_t;
+#endif
+
+#ifndef kroundup32
+#define kroundup32(x) (--(x), (x)|=(x)>>1, (x)|=(x)>>2, (x)|=(x)>>4, (x)|=(x)>>8, (x)|=(x)>>16, ++(x))
+#endif
+
+/**
+ * hts_expand() - expands memory block pointed to by $ptr;
+ * hts_expand0() the latter sets the newly allocated part to 0.
+ *
+ * @param n requested number of elements of type type_t
+ * @param m size of memory allocated
+ */
+#define hts_expand(type_t, n, m, ptr) if ((n) > (m)) { \
+ (m) = (n); kroundup32(m); \
+ (ptr) = (type_t*)realloc((ptr), (m) * sizeof(type_t)); \
+ }
+#define hts_expand0(type_t, n, m, ptr) if ((n) > (m)) { \
+ int t = (m); (m) = (n); kroundup32(m); \
+ (ptr) = (type_t*)realloc((ptr), (m) * sizeof(type_t)); \
+ memset(((type_t*)ptr)+t,0,sizeof(type_t)*((m)-t)); \
+ }
+
+/************
+ * File I/O *
+ ************/
+
+// Add new entries only at the end (but before the *_maximum entry)
+// of these enums, as their numbering is part of the htslib ABI.
+
+enum htsFormatCategory {
+ unknown_category,
+ sequence_data, // Sequence data -- SAM, BAM, CRAM, etc
+ variant_data, // Variant calling data -- VCF, BCF, etc
+ index_file, // Index file associated with some data file
+ region_list, // Coordinate intervals or regions -- BED, etc
+ category_maximum = 32767
+};
+
+enum htsExactFormat {
+ unknown_format,
+ binary_format, text_format,
+ sam, bam, bai, cram, crai, vcf, bcf, csi, gzi, tbi, bed,
+ format_maximum = 32767
+};
+
+enum htsCompression {
+ no_compression, gzip, bgzf, custom,
+ compression_maximum = 32767
+};
+
+typedef struct htsFormat {
+ enum htsFormatCategory category;
+ enum htsExactFormat format;
+ struct { short major, minor; } version;
+ enum htsCompression compression;
+ short compression_level; // currently unused
+ void *specific; // format specific options; see struct hts_opt.
+} htsFormat;
+
+// Maintainers note htsFile cannot be an opaque structure because some of its
+// fields are part of libhts.so's ABI (hence these fields must not be moved):
+// - fp is used in the public sam_itr_next()/etc macros
+// - is_bin is used directly in samtools <= 1.1 and bcftools <= 1.1
+// - is_write and is_cram are used directly in samtools <= 1.1
+// - fp is used directly in samtools (up to and including current develop)
+// - line is used directly in bcftools (up to and including current develop)
+typedef struct {
+ uint32_t is_bin:1, is_write:1, is_be:1, is_cram:1, dummy:28;
+ int64_t lineno;
+ kstring_t line;
+ char *fn, *fn_aux;
+ union {
+ BGZF *bgzf;
+ struct cram_fd *cram;
+ struct hFILE *hfile;
+ void *voidp;
+ } fp;
+ htsFormat format;
+} htsFile;
+
+// REQUIRED_FIELDS
+enum sam_fields {
+ SAM_QNAME = 0x00000001,
+ SAM_FLAG = 0x00000002,
+ SAM_RNAME = 0x00000004,
+ SAM_POS = 0x00000008,
+ SAM_MAPQ = 0x00000010,
+ SAM_CIGAR = 0x00000020,
+ SAM_RNEXT = 0x00000040,
+ SAM_PNEXT = 0x00000080,
+ SAM_TLEN = 0x00000100,
+ SAM_SEQ = 0x00000200,
+ SAM_QUAL = 0x00000400,
+ SAM_AUX = 0x00000800,
+ SAM_RGAUX = 0x00001000,
+};
+
+// Mostly CRAM only, but this could also include other format options
+enum hts_fmt_option {
+ // CRAM specific
+ CRAM_OPT_DECODE_MD,
+ CRAM_OPT_PREFIX,
+ CRAM_OPT_VERBOSITY, // make general
+ CRAM_OPT_SEQS_PER_SLICE,
+ CRAM_OPT_SLICES_PER_CONTAINER,
+ CRAM_OPT_RANGE,
+ CRAM_OPT_VERSION, // rename to cram_version?
+ CRAM_OPT_EMBED_REF,
+ CRAM_OPT_IGNORE_MD5,
+ CRAM_OPT_REFERENCE, // make general
+ CRAM_OPT_MULTI_SEQ_PER_SLICE,
+ CRAM_OPT_NO_REF,
+ CRAM_OPT_USE_BZIP2,
+ CRAM_OPT_SHARED_REF,
+ CRAM_OPT_NTHREADS, // deprecated, use HTS_OPT_NTHREADS
+ CRAM_OPT_THREAD_POOL,// make general
+ CRAM_OPT_USE_LZMA,
+ CRAM_OPT_USE_RANS,
+ CRAM_OPT_REQUIRED_FIELDS,
+
+ // General purpose
+ HTS_OPT_COMPRESSION_LEVEL = 100,
+ HTS_OPT_NTHREADS,
+};
+
+// For backwards compatibility
+#define cram_option hts_fmt_option
+
+typedef struct hts_opt {
+ char *arg; // string form, strdup()ed
+ enum hts_fmt_option opt; // tokenised key
+ union { // ... and value
+ int i;
+ char *s;
+ } val;
+ struct hts_opt *next;
+} hts_opt;
+
+#define HTS_FILE_OPTS_INIT {{0},0}
+
+/**********************
+ * Exported functions *
+ **********************/
+
+/*
+ * Parses arg and appends it to the option list.
+ *
+ * Returns 0 on success;
+ * -1 on failure.
+ */
+int hts_opt_add(hts_opt **opts, const char *c_arg);
+
+/*
+ * Applies an hts_opt option list to a given htsFile.
+ *
+ * Returns 0 on success
+ * -1 on failure
+ */
+int hts_opt_apply(htsFile *fp, hts_opt *opts);
+
+/*
+ * Frees an hts_opt list.
+ */
+void hts_opt_free(hts_opt *opts);
+
+/*
+ * Accepts a string file format (sam, bam, cram, vcf, bam) optionally
+ * followed by a comma separated list of key=value options and splits
+ * these up into the fields of htsFormat struct.
+ *
+ * Returns 0 on success
+ * -1 on failure.
+ */
+int hts_parse_format(htsFormat *opt, const char *str);
+
+/*
+ * Tokenise options as (key(=value)?,)*(key(=value)?)?
+ * NB: No provision for ',' appearing in the value!
+ * Add backslashing rules?
+ *
+ * This could be used as part of a general command line option parser or
+ * as a string concatenated onto the file open mode.
+ *
+ * Returns 0 on success
+ * -1 on failure.
+ */
+int hts_parse_opt_list(htsFormat *opt, const char *str);
+
+extern int hts_verbose;
+
+/*! @abstract Table for converting a nucleotide character to 4-bit encoding.
+The input character may be either an IUPAC ambiguity code, '=' for 0, or
+'0'/'1'/'2'/'3' for a result of 1/2/4/8. The result is encoded as 1/2/4/8
+for A/C/G/T or combinations of these bits for ambiguous bases.
+*/
+extern const unsigned char seq_nt16_table[256];
+
+/*! @abstract Table for converting a 4-bit encoded nucleotide to an IUPAC
+ambiguity code letter (or '=' when given 0).
+*/
+extern const char seq_nt16_str[];
+
+/*! @abstract Table for converting a 4-bit encoded nucleotide to about 2 bits.
+Returns 0/1/2/3 for 1/2/4/8 (i.e., A/C/G/T), or 4 otherwise (0 or ambiguous).
+*/
+extern const int seq_nt16_int[];
+
+/*!
+ @abstract Get the htslib version number
+ @return For released versions, a string like "N.N[.N]"; or git describe
+ output if using a library built within a Git repository.
+*/
+const char *hts_version(void);
+
+/*!
+ @abstract Determine format by peeking at the start of a file
+ @param fp File opened for reading, positioned at the beginning
+ @param fmt Format structure that will be filled out on return
+ @return 0 for success, or negative if an error occurred.
+*/
+int hts_detect_format(struct hFILE *fp, htsFormat *fmt);
+
+/*!
+ @abstract Get a human-readable description of the file format
+ @param fmt Format structure holding type, version, compression, etc.
+ @return Description string, to be freed by the caller after use.
+*/
+char *hts_format_description(const htsFormat *format);
+
+/*!
+ @abstract Open a SAM/BAM/CRAM/VCF/BCF/etc file
+ @param fn The file name or "-" for stdin/stdout
+ @param mode Mode matching / [rwa][bceguxz0-9]* /
+ @discussion
+ With 'r' opens for reading; any further format mode letters are ignored
+ as the format is detected by checking the first few bytes or BGZF blocks
+ of the file. With 'w' or 'a' opens for writing or appending, with format
+ specifier letters:
+ b binary format (BAM, BCF, etc) rather than text (SAM, VCF, etc)
+ c CRAM format
+ g gzip compressed
+ u uncompressed
+ z bgzf compressed
+ [0-9] zlib compression level
+ and with non-format option letters (for any of 'r'/'w'/'a'):
+ e close the file on exec(2) (opens with O_CLOEXEC, where supported)
+ x create the file exclusively (opens with O_EXCL, where supported)
+ Note that there is a distinction between 'u' and '0': the first yields
+ plain uncompressed output whereas the latter outputs uncompressed data
+ wrapped in the zlib format.
+ @example
+ [rw]b .. compressed BCF, BAM, FAI
+ [rw]bu .. uncompressed BCF
+ [rw]z .. compressed VCF
+ [rw] .. uncompressed VCF
+*/
+htsFile *hts_open(const char *fn, const char *mode);
+
+/*!
+ @abstract Open a SAM/BAM/CRAM/VCF/BCF/etc file
+ @param fn The file name or "-" for stdin/stdout
+ @param mode Open mode, as per hts_open()
+ @param fmt Optional format specific parameters
+ @discussion
+ See hts_open() for description of fn and mode.
+ // TODO Update documentation for s/opts/fmt/
+ Opts contains a format string (sam, bam, cram, vcf, bcf) which will,
+ if defined, override mode. Opts also contains a linked list of hts_opt
+ structures to apply to the open file handle. These can contain things
+ like pointers to the reference or information on compression levels,
+ block sizes, etc.
+*/
+htsFile *hts_open_format(const char *fn, const char *mode, const htsFormat *fmt);
+
+/*!
+ @abstract Open an existing stream as a SAM/BAM/CRAM/VCF/BCF/etc file
+ @param fn The already-open file handle
+ @param mode Open mode, as per hts_open()
+*/
+htsFile *hts_hopen(struct hFILE *fp, const char *fn, const char *mode);
+
+/*!
+ @abstract Close a file handle, flushing buffered data for output streams
+ @param fp The file handle to be closed
+ @return 0 for success, or negative if an error occurred.
+*/
+int hts_close(htsFile *fp);
+
+/*!
+ @abstract Returns the file's format information
+ @param fp The file handle
+ @return Read-only pointer to the file's htsFormat.
+*/
+const htsFormat *hts_get_format(htsFile *fp);
+
+/*!
+ @ abstract Returns a string containing the file format extension.
+ @ param format Format structure containing the file type.
+ @ return A string ("sam", "bam", etc) or "?" for unknown formats.
+ */
+const char *hts_format_file_extension(const htsFormat *format);
+
+/*!
+ @abstract Sets a specified CRAM option on the open file handle.
+ @param fp The file handle open the open file.
+ @param opt The CRAM_OPT_* option.
+ @param ... Optional arguments, dependent on the option used.
+ @return 0 for success, or negative if an error occurred.
+*/
+int hts_set_opt(htsFile *fp, enum hts_fmt_option opt, ...);
+
+int hts_getline(htsFile *fp, int delimiter, kstring_t *str);
+char **hts_readlines(const char *fn, int *_n);
+/*!
+ @abstract Parse comma-separated list or read list from a file
+ @param list File name or comma-separated list
+ @param is_file
+ @param _n Size of the output array (number of items read)
+ @return NULL on failure or pointer to newly allocated array of
+ strings
+*/
+char **hts_readlist(const char *fn, int is_file, int *_n);
+
+/*!
+ @abstract Create extra threads to aid compress/decompression for this file
+ @param fp The file handle
+ @param n The number of worker threads to create
+ @return 0 for success, or negative if an error occurred.
+ @notes THIS THREADING API IS LIKELY TO CHANGE IN FUTURE.
+*/
+int hts_set_threads(htsFile *fp, int n);
+
+/*!
+ @abstract Set .fai filename for a file opened for reading
+ @return 0 for success, negative on failure
+ @discussion
+ Called before *_hdr_read(), this provides the name of a .fai file
+ used to provide a reference list if the htsFile contains no @SQ headers.
+*/
+int hts_set_fai_filename(htsFile *fp, const char *fn_aux);
+
+/************
+ * Indexing *
+ ************/
+
+/*!
+These HTS_IDX_* macros are used as special tid values for hts_itr_query()/etc,
+producing iterators operating as follows:
+ - HTS_IDX_NOCOOR iterates over unmapped reads sorted at the end of the file
+ - HTS_IDX_START iterates over the entire file
+ - HTS_IDX_REST iterates from the current position to the end of the file
+ - HTS_IDX_NONE always returns "no more alignment records"
+When one of these special tid values is used, beg and end are ignored.
+When REST or NONE is used, idx is also ignored and may be NULL.
+*/
+#define HTS_IDX_NOCOOR (-2)
+#define HTS_IDX_START (-3)
+#define HTS_IDX_REST (-4)
+#define HTS_IDX_NONE (-5)
+
+#define HTS_FMT_CSI 0
+#define HTS_FMT_BAI 1
+#define HTS_FMT_TBI 2
+#define HTS_FMT_CRAI 3
+
+struct __hts_idx_t;
+typedef struct __hts_idx_t hts_idx_t;
+
+typedef struct {
+ uint64_t u, v;
+} hts_pair64_t;
+
+typedef int hts_readrec_func(BGZF *fp, void *data, void *r, int *tid, int *beg, int *end);
+
+typedef struct {
+ uint32_t read_rest:1, finished:1, dummy:29;
+ int tid, beg, end, n_off, i;
+ int curr_tid, curr_beg, curr_end;
+ uint64_t curr_off;
+ hts_pair64_t *off;
+ hts_readrec_func *readrec;
+ struct {
+ int n, m;
+ int *a;
+ } bins;
+} hts_itr_t;
+
+ #define hts_bin_first(l) (((1<<(((l)<<1) + (l))) - 1) / 7)
+ #define hts_bin_parent(l) (((l) - 1) >> 3)
+
+ hts_idx_t *hts_idx_init(int n, int fmt, uint64_t offset0, int min_shift, int n_lvls);
+ void hts_idx_destroy(hts_idx_t *idx);
+ int hts_idx_push(hts_idx_t *idx, int tid, int beg, int end, uint64_t offset, int is_mapped);
+ void hts_idx_finish(hts_idx_t *idx, uint64_t final_offset);
+
+/// Save an index to a file
+/** @param idx Index to be written
+ @param fn Input BAM/BCF/etc filename, to which .bai/.csi/etc will be added
+ @param fmt One of the HTS_FMT_* index formats
+ @return 0 if successful, or negative if an error occurred.
+*/
+int hts_idx_save(const hts_idx_t *idx, const char *fn, int fmt) HTS_RESULT_USED;
+
+/// Save an index to a specific file
+/** @param idx Index to be written
+ @param fn Input BAM/BCF/etc filename
+ @param fnidx Output filename, or NULL to add .bai/.csi/etc to @a fn
+ @param fmt One of the HTS_FMT_* index formats
+ @return 0 if successful, or negative if an error occurred.
+*/
+int hts_idx_save_as(const hts_idx_t *idx, const char *fn, const char *fnidx, int fmt) HTS_RESULT_USED;
+
+/// Load an index file
+/** @param fn BAM/BCF/etc filename, to which .bai/.csi/etc will be added or
+ the extension substituted, to search for an existing index file
+ @param fmt One of the HTS_FMT_* index formats
+ @return The index, or NULL if an error occurred.
+*/
+hts_idx_t *hts_idx_load(const char *fn, int fmt);
+
+/// Load a specific index file
+/** @param fn Input BAM/BCF/etc filename
+ @param fnidx The input index filename
+ @return The index, or NULL if an error occurred.
+*/
+hts_idx_t *hts_idx_load2(const char *fn, const char *fnidx);
+
+ uint8_t *hts_idx_get_meta(hts_idx_t *idx, int *l_meta);
+ void hts_idx_set_meta(hts_idx_t *idx, int l_meta, uint8_t *meta, int is_copy);
+
+ int hts_idx_get_stat(const hts_idx_t* idx, int tid, uint64_t* mapped, uint64_t* unmapped);
+ uint64_t hts_idx_get_n_no_coor(const hts_idx_t* idx);
+
+
+#define HTS_PARSE_THOUSANDS_SEP 1 ///< Ignore ',' separators within numbers
+
+/// Parse a numeric string
+/** The number may be expressed in scientific notation, and optionally may
+ contain commas in the integer part (before any decimal point or E notation).
+ @param str String to be parsed
+ @param strend If non-NULL, set on return to point to the first character
+ in @a str after those forming the parsed number
+ @param flags Or'ed-together combination of HTS_PARSE_* flags
+ @return Converted value of the parsed number.
+
+ When @a strend is NULL, a warning will be printed (if hts_verbose is 2
+ or more) if there are any trailing characters after the number.
+*/
+long long hts_parse_decimal(const char *str, char **strend, int flags);
+
+/// Parse a "CHR:START-END"-style region string
+/** @param str String to be parsed
+ @param beg Set on return to the 0-based start of the region
+ @param end Set on return to the 1-based end of the region
+ @return Pointer to the colon or '\0' after the reference sequence name,
+ or NULL if @a str could not be parsed.
+*/
+const char *hts_parse_reg(const char *str, int *beg, int *end);
+
+ hts_itr_t *hts_itr_query(const hts_idx_t *idx, int tid, int beg, int end, hts_readrec_func *readrec);
+ void hts_itr_destroy(hts_itr_t *iter);
+
+ typedef int (*hts_name2id_f)(void*, const char*);
+ typedef const char *(*hts_id2name_f)(void*, int);
+ typedef hts_itr_t *hts_itr_query_func(const hts_idx_t *idx, int tid, int beg, int end, hts_readrec_func *readrec);
+
+ hts_itr_t *hts_itr_querys(const hts_idx_t *idx, const char *reg, hts_name2id_f getid, void *hdr, hts_itr_query_func *itr_query, hts_readrec_func *readrec);
+ int hts_itr_next(BGZF *fp, hts_itr_t *iter, void *r, void *data) HTS_RESULT_USED;
+ const char **hts_idx_seqnames(const hts_idx_t *idx, int *n, hts_id2name_f getid, void *hdr); // free only the array, not the values
+
+ /**
+ * hts_file_type() - Convenience function to determine file type
+ * DEPRECATED: This function has been replaced by hts_detect_format().
+ * It and these FT_* macros will be removed in a future HTSlib release.
+ */
+ #define FT_UNKN 0
+ #define FT_GZ 1
+ #define FT_VCF 2
+ #define FT_VCF_GZ (FT_GZ|FT_VCF)
+ #define FT_BCF (1<<2)
+ #define FT_BCF_GZ (FT_GZ|FT_BCF)
+ #define FT_STDIN (1<<3)
+ int hts_file_type(const char *fname);
+
+
+ /**********************
+ * MD5 implementation *
+ **********************/
+
+ struct hts_md5_context;
+ typedef struct hts_md5_context hts_md5_context;
+
+ /*! @abstract Intialises an MD5 context.
+ * @discussion
+ * The expected use is to allocate an hts_md5_context using
+ * hts_md5_init(). This pointer is then passed into one or more calls
+ * of hts_md5_update() to compute successive internal portions of the
+ * MD5 sum, which can then be externalised as a full 16-byte MD5sum
+ * calculation by calling hts_md5_final(). This can then be turned
+ * into ASCII via hts_md5_hex().
+ *
+ * To dealloate any resources created by hts_md5_init() call the
+ * hts_md5_destroy() function.
+ *
+ * @return hts_md5_context pointer on success, NULL otherwise.
+ */
+ hts_md5_context *hts_md5_init(void);
+
+ /*! @abstract Updates the context with the MD5 of the data. */
+ void hts_md5_update(hts_md5_context *ctx, const void *data, unsigned long size);
+
+ /*! @abstract Computes the final 128-bit MD5 hash from the given context */
+ void hts_md5_final(unsigned char *digest, hts_md5_context *ctx);
+
+ /*! @abstract Resets an md5_context to the initial state, as returned
+ * by hts_md5_init().
+ */
+ void hts_md5_reset(hts_md5_context *ctx);
+
+ /*! @abstract Converts a 128-bit MD5 hash into a 33-byte nul-termninated
+ * hex string.
+ */
+ void hts_md5_hex(char *hex, const unsigned char *digest);
+
+ /*! @abstract Deallocates any memory allocated by hts_md5_init. */
+ void hts_md5_destroy(hts_md5_context *ctx);
+
+
+static inline int hts_reg2bin(int64_t beg, int64_t end, int min_shift, int n_lvls)
+{
+ int l, s = min_shift, t = ((1<<((n_lvls<<1) + n_lvls)) - 1) / 7;
+ for (--end, l = n_lvls; l > 0; --l, s += 3, t -= 1<<((l<<1)+l))
+ if (beg>>s == end>>s) return t + (beg>>s);
+ return 0;
+}
+
+static inline int hts_bin_bot(int bin, int n_lvls)
+{
+ int l, b;
+ for (l = 0, b = bin; b; ++l, b = hts_bin_parent(b)); // compute the level of bin
+ return (bin - hts_bin_first(l)) << (n_lvls - l) * 3;
+}
+
+/**************
+ * Endianness *
+ **************/
+
+static inline int ed_is_big(void)
+{
+ long one= 1;
+ return !(*((char *)(&one)));
+}
+static inline uint16_t ed_swap_2(uint16_t v)
+{
+ return (uint16_t)(((v & 0x00FF00FFU) << 8) | ((v & 0xFF00FF00U) >> 8));
+}
+static inline void *ed_swap_2p(void *x)
+{
+ *(uint16_t*)x = ed_swap_2(*(uint16_t*)x);
+ return x;
+}
+static inline uint32_t ed_swap_4(uint32_t v)
+{
+ v = ((v & 0x0000FFFFU) << 16) | (v >> 16);
+ return ((v & 0x00FF00FFU) << 8) | ((v & 0xFF00FF00U) >> 8);
+}
+static inline void *ed_swap_4p(void *x)
+{
+ *(uint32_t*)x = ed_swap_4(*(uint32_t*)x);
+ return x;
+}
+static inline uint64_t ed_swap_8(uint64_t v)
+{
+ v = ((v & 0x00000000FFFFFFFFLLU) << 32) | (v >> 32);
+ v = ((v & 0x0000FFFF0000FFFFLLU) << 16) | ((v & 0xFFFF0000FFFF0000LLU) >> 16);
+ return ((v & 0x00FF00FF00FF00FFLLU) << 8) | ((v & 0xFF00FF00FF00FF00LLU) >> 8);
+}
+static inline void *ed_swap_8p(void *x)
+{
+ *(uint64_t*)x = ed_swap_8(*(uint64_t*)x);
+ return x;
+}
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* hts_defs.h -- Miscellaneous definitions.
+
+ Copyright (C) 2013-2015 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_HTS_DEFS_H
+#define HTSLIB_HTS_DEFS_H
+
+#ifdef __clang__
+#ifdef __has_attribute
+#define HTS_COMPILER_HAS(attribute) __has_attribute(attribute)
+#endif
+
+#elif defined __GNUC__
+#define HTS_GCC_AT_LEAST(major, minor) \
+ (__GNUC__ > (major) || (__GNUC__ == (major) && __GNUC_MINOR__ >= (minor)))
+#endif
+
+#ifndef HTS_COMPILER_HAS
+#define HTS_COMPILER_HAS(attribute) 0
+#endif
+#ifndef HTS_GCC_AT_LEAST
+#define HTS_GCC_AT_LEAST(major, minor) 0
+#endif
+
+#if HTS_COMPILER_HAS(__noreturn__) || HTS_GCC_AT_LEAST(3,0)
+#define HTS_NORETURN __attribute__ ((__noreturn__))
+#else
+#define HTS_NORETURN
+#endif
+
+// GCC introduced warn_unused_result in 3.4 but added -Wno-unused-result later
+#if HTS_COMPILER_HAS(__warn_unused_result__) || HTS_GCC_AT_LEAST(4,5)
+#define HTS_RESULT_USED __attribute__ ((__warn_unused_result__))
+#else
+#define HTS_RESULT_USED
+#endif
+
+#if HTS_COMPILER_HAS(__unused__) || HTS_GCC_AT_LEAST(3,0)
+#define HTS_UNUSED __attribute__ ((__unused__))
+#else
+#define HTS_UNUSED
+#endif
+
+#if HTS_COMPILER_HAS(__deprecated__) || HTS_GCC_AT_LEAST(4,5)
+#define HTS_DEPRECATED(message) __attribute__ ((__deprecated__ (message)))
+#elif HTS_GCC_AT_LEAST(3,1)
+#define HTS_DEPRECATED(message) __attribute__ ((__deprecated__))
+#else
+#define HTS_DEPRECATED(message)
+#endif
+
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (C) 2015 Genome Research Ltd.
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+#ifndef KBITSET_H
+#define KBITSET_H
+
+/* Example of using kbitset_t, which represents a subset of {0,..., N-1},
+ where N is the size specified in kbs_init().
+
+ kbitset_t *bset = kbs_init(100);
+ kbs_insert(bset, 5);
+ kbs_insert(bset, 68);
+ kbs_delete(bset, 37);
+ // ...
+
+ if (kbs_exists(bset, 68)) printf("68 present\n");
+
+ kbitset_iter itr;
+ int i;
+ kbs_start(&itr);
+ while ((i = kbs_next(bset, &itr)) >= 0)
+ printf("%d present\n", i);
+
+ kbs_destroy(bset);
+
+ Example of declaring a kbitset_t-using function in a header file, so that
+ only source files that actually use process() need to include <kbitset.h>:
+
+ struct kbitset_t;
+ void process(struct kbitset_t *bset);
+*/
+
+#include <limits.h>
+#include <stdlib.h>
+#include <string.h>
+
+#define KBS_ELTBITS (CHAR_BIT * sizeof (unsigned long))
+#define KBS_ELT(i) ((i) / KBS_ELTBITS)
+#define KBS_MASK(i) (1UL << ((i) % KBS_ELTBITS))
+
+typedef struct kbitset_t {
+ size_t n;
+ unsigned long b[1];
+} kbitset_t;
+
+// Initialise a bit set capable of holding ni integers, 0 <= i < ni.
+// The set returned is empty if fill == 0, or all of [0,ni) otherwise.
+static inline kbitset_t *kbs_init2(size_t ni, int fill)
+{
+ size_t n = (ni + KBS_ELTBITS-1) / KBS_ELTBITS;
+ kbitset_t *bs =
+ (kbitset_t *) malloc(sizeof(kbitset_t) + n * sizeof(unsigned long));
+ if (bs == NULL) return NULL;
+ bs->n = n;
+ memset(bs->b, fill? ~0 : 0, n * sizeof (unsigned long));
+ bs->b[n] = ~0UL;
+ return bs;
+}
+
+// Initialise an empty bit set capable of holding ni integers, 0 <= i < ni.
+static inline kbitset_t *kbs_init(size_t ni)
+{
+ return kbs_init2(ni, 0);
+}
+
+// Destroy a bit set.
+static inline void kbs_destroy(kbitset_t *bs)
+{
+ free(bs);
+}
+
+// Reset the bit set to empty.
+static inline void kbs_clear(kbitset_t *bs)
+{
+ memset(bs->b, 0, bs->n * sizeof (unsigned long));
+}
+
+// Reset the bit set to all of [0,ni).
+static inline void kbs_insert_all(kbitset_t *bs)
+{
+ memset(bs->b, ~0, bs->n * sizeof (unsigned long));
+}
+
+// Insert an element into the bit set.
+static inline void kbs_insert(kbitset_t *bs, int i)
+{
+ bs->b[KBS_ELT(i)] |= KBS_MASK(i);
+}
+
+// Remove an element from the bit set.
+static inline void kbs_delete(kbitset_t *bs, int i)
+{
+ bs->b[KBS_ELT(i)] &= ~KBS_MASK(i);
+}
+
+// Test whether the bit set contains the element.
+static inline int kbs_exists(const kbitset_t *bs, int i)
+{
+ return (bs->b[KBS_ELT(i)] & KBS_MASK(i)) != 0;
+}
+
+typedef struct kbitset_iter_t {
+ unsigned long mask;
+ size_t elt;
+ int i;
+} kbitset_iter_t;
+
+// Initialise or reset a bit set iterator.
+static inline void kbs_start(kbitset_iter_t *itr)
+{
+ itr->mask = 1;
+ itr->elt = 0;
+ itr->i = 0;
+}
+
+// Return the next element contained in the bit set, or -1 if there are no more.
+static inline int kbs_next(const kbitset_t *bs, kbitset_iter_t *itr)
+{
+ unsigned long b = bs->b[itr->elt];
+
+ for (;;) {
+ if (itr->mask == 0) {
+ while ((b = bs->b[++itr->elt]) == 0) itr->i += KBS_ELTBITS;
+ if (itr->elt == bs->n) return -1;
+ itr->mask = 1;
+ }
+
+ if (b & itr->mask) break;
+
+ itr->i++;
+ itr->mask <<= 1;
+ }
+
+ itr->mask <<= 1;
+ return itr->i++;
+}
+
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (C) 2010, 2013 Genome Research Ltd.
+ Copyright (C) 2011 Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+#ifndef HTSLIB_KFUNC_H
+#define HTSLIB_KFUNC_H
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/* Log gamma function
+ * \log{\Gamma(z)}
+ * AS245, 2nd algorithm, http://lib.stat.cmu.edu/apstat/245
+ */
+double kf_lgamma(double z);
+
+/* complementary error function
+ * \frac{2}{\sqrt{\pi}} \int_x^{\infty} e^{-t^2} dt
+ * AS66, 2nd algorithm, http://lib.stat.cmu.edu/apstat/66
+ */
+double kf_erfc(double x);
+
+/* The following computes regularized incomplete gamma functions.
+ * Formulas are taken from Wiki, with additional input from Numerical
+ * Recipes in C (for modified Lentz's algorithm) and AS245
+ * (http://lib.stat.cmu.edu/apstat/245).
+ *
+ * A good online calculator is available at:
+ *
+ * http://www.danielsoper.com/statcalc/calc23.aspx
+ *
+ * It calculates upper incomplete gamma function, which equals
+ * kf_gammaq(s,z)*tgamma(s).
+ */
+
+double kf_gammap(double s, double z);
+double kf_gammaq(double s, double z);
+
+/* Regularized incomplete beta function. The method is taken from
+ * Numerical Recipe in C, 2nd edition, section 6.4. The following web
+ * page calculates the incomplete beta function, which equals
+ * kf_betai(a,b,x) * gamma(a) * gamma(b) / gamma(a+b):
+ *
+ * http://www.danielsoper.com/statcalc/calc36.aspx
+ */
+double kf_betai(double a, double b, double x);
+
+/*
+ * n11 n12 | n1_
+ * n21 n22 | n2_
+ * -----------+----
+ * n_1 n_2 | n
+ */
+double kt_fisher_exact(int n11, int n12, int n21, int n22, double *_left, double *_right, double *two);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (c) 2008, 2009, 2011 by Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+/*
+ An example:
+
+#include "khash.h"
+KHASH_MAP_INIT_INT(32, char)
+int main() {
+ int ret, is_missing;
+ khiter_t k;
+ khash_t(32) *h = kh_init(32);
+ k = kh_put(32, h, 5, &ret);
+ kh_value(h, k) = 10;
+ k = kh_get(32, h, 10);
+ is_missing = (k == kh_end(h));
+ k = kh_get(32, h, 5);
+ kh_del(32, h, k);
+ for (k = kh_begin(h); k != kh_end(h); ++k)
+ if (kh_exist(h, k)) kh_value(h, k) = 1;
+ kh_destroy(32, h);
+ return 0;
+}
+*/
+
+/*
+ 2013-05-02 (0.2.8):
+
+ * Use quadratic probing. When the capacity is power of 2, stepping function
+ i*(i+1)/2 guarantees to traverse each bucket. It is better than double
+ hashing on cache performance and is more robust than linear probing.
+
+ In theory, double hashing should be more robust than quadratic probing.
+ However, my implementation is probably not for large hash tables, because
+ the second hash function is closely tied to the first hash function,
+ which reduce the effectiveness of double hashing.
+
+ Reference: http://research.cs.vt.edu/AVresearch/hashing/quadratic.php
+
+ 2011-12-29 (0.2.7):
+
+ * Minor code clean up; no actual effect.
+
+ 2011-09-16 (0.2.6):
+
+ * The capacity is a power of 2. This seems to dramatically improve the
+ speed for simple keys. Thank Zilong Tan for the suggestion. Reference:
+
+ - http://code.google.com/p/ulib/
+ - http://nothings.org/computer/judy/
+
+ * Allow to optionally use linear probing which usually has better
+ performance for random input. Double hashing is still the default as it
+ is more robust to certain non-random input.
+
+ * Added Wang's integer hash function (not used by default). This hash
+ function is more robust to certain non-random input.
+
+ 2011-02-14 (0.2.5):
+
+ * Allow to declare global functions.
+
+ 2009-09-26 (0.2.4):
+
+ * Improve portability
+
+ 2008-09-19 (0.2.3):
+
+ * Corrected the example
+ * Improved interfaces
+
+ 2008-09-11 (0.2.2):
+
+ * Improved speed a little in kh_put()
+
+ 2008-09-10 (0.2.1):
+
+ * Added kh_clear()
+ * Fixed a compiling error
+
+ 2008-09-02 (0.2.0):
+
+ * Changed to token concatenation which increases flexibility.
+
+ 2008-08-31 (0.1.2):
+
+ * Fixed a bug in kh_get(), which has not been tested previously.
+
+ 2008-08-31 (0.1.1):
+
+ * Added destructor
+*/
+
+
+#ifndef __AC_KHASH_H
+#define __AC_KHASH_H
+
+/*!
+ @header
+
+ Generic hash table library.
+ */
+
+#define AC_VERSION_KHASH_H "0.2.8"
+
+#include <stdlib.h>
+#include <string.h>
+#include <limits.h>
+
+/* compiler specific configuration */
+
+#if UINT_MAX == 0xffffffffu
+typedef unsigned int khint32_t;
+#elif ULONG_MAX == 0xffffffffu
+typedef unsigned long khint32_t;
+#endif
+
+#if ULONG_MAX == ULLONG_MAX
+typedef unsigned long khint64_t;
+#else
+typedef unsigned long long khint64_t;
+#endif
+
+#ifndef kh_inline
+#ifdef _MSC_VER
+#define kh_inline __inline
+#else
+#define kh_inline inline
+#endif
+#endif /* kh_inline */
+
+#ifndef klib_unused
+#if (defined __clang__ && __clang_major__ >= 3) || (defined __GNUC__ && __GNUC__ >= 3)
+#define klib_unused __attribute__ ((__unused__))
+#else
+#define klib_unused
+#endif
+#endif /* klib_unused */
+
+typedef khint32_t khint_t;
+typedef khint_t khiter_t;
+
+#define __ac_isempty(flag, i) ((flag[i>>4]>>((i&0xfU)<<1))&2)
+#define __ac_isdel(flag, i) ((flag[i>>4]>>((i&0xfU)<<1))&1)
+#define __ac_iseither(flag, i) ((flag[i>>4]>>((i&0xfU)<<1))&3)
+#define __ac_set_isdel_false(flag, i) (flag[i>>4]&=~(1ul<<((i&0xfU)<<1)))
+#define __ac_set_isempty_false(flag, i) (flag[i>>4]&=~(2ul<<((i&0xfU)<<1)))
+#define __ac_set_isboth_false(flag, i) (flag[i>>4]&=~(3ul<<((i&0xfU)<<1)))
+#define __ac_set_isdel_true(flag, i) (flag[i>>4]|=1ul<<((i&0xfU)<<1))
+
+#define __ac_fsize(m) ((m) < 16? 1 : (m)>>4)
+
+#ifndef kroundup32
+#define kroundup32(x) (--(x), (x)|=(x)>>1, (x)|=(x)>>2, (x)|=(x)>>4, (x)|=(x)>>8, (x)|=(x)>>16, ++(x))
+#endif
+
+#ifndef kcalloc
+#define kcalloc(N,Z) calloc(N,Z)
+#endif
+#ifndef kmalloc
+#define kmalloc(Z) malloc(Z)
+#endif
+#ifndef krealloc
+#define krealloc(P,Z) realloc(P,Z)
+#endif
+#ifndef kfree
+#define kfree(P) free(P)
+#endif
+
+static const double __ac_HASH_UPPER = 0.77;
+
+#define __KHASH_TYPE(name, khkey_t, khval_t) \
+ typedef struct kh_##name##_s { \
+ khint_t n_buckets, size, n_occupied, upper_bound; \
+ khint32_t *flags; \
+ khkey_t *keys; \
+ khval_t *vals; \
+ } kh_##name##_t;
+
+#define __KHASH_PROTOTYPES(name, khkey_t, khval_t) \
+ extern kh_##name##_t *kh_init_##name(void); \
+ extern void kh_destroy_##name(kh_##name##_t *h); \
+ extern void kh_clear_##name(kh_##name##_t *h); \
+ extern khint_t kh_get_##name(const kh_##name##_t *h, khkey_t key); \
+ extern int kh_resize_##name(kh_##name##_t *h, khint_t new_n_buckets); \
+ extern khint_t kh_put_##name(kh_##name##_t *h, khkey_t key, int *ret); \
+ extern void kh_del_##name(kh_##name##_t *h, khint_t x);
+
+#define __KHASH_IMPL(name, SCOPE, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal) \
+ SCOPE kh_##name##_t *kh_init_##name(void) { \
+ return (kh_##name##_t*)kcalloc(1, sizeof(kh_##name##_t)); \
+ } \
+ SCOPE void kh_destroy_##name(kh_##name##_t *h) \
+ { \
+ if (h) { \
+ kfree((void *)h->keys); kfree(h->flags); \
+ kfree((void *)h->vals); \
+ kfree(h); \
+ } \
+ } \
+ SCOPE void kh_clear_##name(kh_##name##_t *h) \
+ { \
+ if (h && h->flags) { \
+ memset(h->flags, 0xaa, __ac_fsize(h->n_buckets) * sizeof(khint32_t)); \
+ h->size = h->n_occupied = 0; \
+ } \
+ } \
+ SCOPE khint_t kh_get_##name(const kh_##name##_t *h, khkey_t key) \
+ { \
+ if (h->n_buckets) { \
+ khint_t k, i, last, mask, step = 0; \
+ mask = h->n_buckets - 1; \
+ k = __hash_func(key); i = k & mask; \
+ last = i; \
+ while (!__ac_isempty(h->flags, i) && (__ac_isdel(h->flags, i) || !__hash_equal(h->keys[i], key))) { \
+ i = (i + (++step)) & mask; \
+ if (i == last) return h->n_buckets; \
+ } \
+ return __ac_iseither(h->flags, i)? h->n_buckets : i; \
+ } else return 0; \
+ } \
+ SCOPE int kh_resize_##name(kh_##name##_t *h, khint_t new_n_buckets) \
+ { /* This function uses 0.25*n_buckets bytes of working space instead of [sizeof(key_t+val_t)+.25]*n_buckets. */ \
+ khint32_t *new_flags = 0; \
+ khint_t j = 1; \
+ { \
+ kroundup32(new_n_buckets); \
+ if (new_n_buckets < 4) new_n_buckets = 4; \
+ if (h->size >= (khint_t)(new_n_buckets * __ac_HASH_UPPER + 0.5)) j = 0; /* requested size is too small */ \
+ else { /* hash table size to be changed (shrink or expand); rehash */ \
+ new_flags = (khint32_t*)kmalloc(__ac_fsize(new_n_buckets) * sizeof(khint32_t)); \
+ if (!new_flags) return -1; \
+ memset(new_flags, 0xaa, __ac_fsize(new_n_buckets) * sizeof(khint32_t)); \
+ if (h->n_buckets < new_n_buckets) { /* expand */ \
+ khkey_t *new_keys = (khkey_t*)krealloc((void *)h->keys, new_n_buckets * sizeof(khkey_t)); \
+ if (!new_keys) { kfree(new_flags); return -1; } \
+ h->keys = new_keys; \
+ if (kh_is_map) { \
+ khval_t *new_vals = (khval_t*)krealloc((void *)h->vals, new_n_buckets * sizeof(khval_t)); \
+ if (!new_vals) { kfree(new_flags); return -1; } \
+ h->vals = new_vals; \
+ } \
+ } /* otherwise shrink */ \
+ } \
+ } \
+ if (j) { /* rehashing is needed */ \
+ for (j = 0; j != h->n_buckets; ++j) { \
+ if (__ac_iseither(h->flags, j) == 0) { \
+ khkey_t key = h->keys[j]; \
+ khval_t val; \
+ khint_t new_mask; \
+ new_mask = new_n_buckets - 1; \
+ if (kh_is_map) val = h->vals[j]; \
+ __ac_set_isdel_true(h->flags, j); \
+ while (1) { /* kick-out process; sort of like in Cuckoo hashing */ \
+ khint_t k, i, step = 0; \
+ k = __hash_func(key); \
+ i = k & new_mask; \
+ while (!__ac_isempty(new_flags, i)) i = (i + (++step)) & new_mask; \
+ __ac_set_isempty_false(new_flags, i); \
+ if (i < h->n_buckets && __ac_iseither(h->flags, i) == 0) { /* kick out the existing element */ \
+ { khkey_t tmp = h->keys[i]; h->keys[i] = key; key = tmp; } \
+ if (kh_is_map) { khval_t tmp = h->vals[i]; h->vals[i] = val; val = tmp; } \
+ __ac_set_isdel_true(h->flags, i); /* mark it as deleted in the old hash table */ \
+ } else { /* write the element and jump out of the loop */ \
+ h->keys[i] = key; \
+ if (kh_is_map) h->vals[i] = val; \
+ break; \
+ } \
+ } \
+ } \
+ } \
+ if (h->n_buckets > new_n_buckets) { /* shrink the hash table */ \
+ h->keys = (khkey_t*)krealloc((void *)h->keys, new_n_buckets * sizeof(khkey_t)); \
+ if (kh_is_map) h->vals = (khval_t*)krealloc((void *)h->vals, new_n_buckets * sizeof(khval_t)); \
+ } \
+ kfree(h->flags); /* free the working space */ \
+ h->flags = new_flags; \
+ h->n_buckets = new_n_buckets; \
+ h->n_occupied = h->size; \
+ h->upper_bound = (khint_t)(h->n_buckets * __ac_HASH_UPPER + 0.5); \
+ } \
+ return 0; \
+ } \
+ SCOPE khint_t kh_put_##name(kh_##name##_t *h, khkey_t key, int *ret) \
+ { \
+ khint_t x; \
+ if (h->n_occupied >= h->upper_bound) { /* update the hash table */ \
+ if (h->n_buckets > (h->size<<1)) { \
+ if (kh_resize_##name(h, h->n_buckets - 1) < 0) { /* clear "deleted" elements */ \
+ *ret = -1; return h->n_buckets; \
+ } \
+ } else if (kh_resize_##name(h, h->n_buckets + 1) < 0) { /* expand the hash table */ \
+ *ret = -1; return h->n_buckets; \
+ } \
+ } /* TODO: to implement automatically shrinking; resize() already support shrinking */ \
+ { \
+ khint_t k, i, site, last, mask = h->n_buckets - 1, step = 0; \
+ x = site = h->n_buckets; k = __hash_func(key); i = k & mask; \
+ if (__ac_isempty(h->flags, i)) x = i; /* for speed up */ \
+ else { \
+ last = i; \
+ while (!__ac_isempty(h->flags, i) && (__ac_isdel(h->flags, i) || !__hash_equal(h->keys[i], key))) { \
+ if (__ac_isdel(h->flags, i)) site = i; \
+ i = (i + (++step)) & mask; \
+ if (i == last) { x = site; break; } \
+ } \
+ if (x == h->n_buckets) { \
+ if (__ac_isempty(h->flags, i) && site != h->n_buckets) x = site; \
+ else x = i; \
+ } \
+ } \
+ } \
+ if (__ac_isempty(h->flags, x)) { /* not present at all */ \
+ h->keys[x] = key; \
+ __ac_set_isboth_false(h->flags, x); \
+ ++h->size; ++h->n_occupied; \
+ *ret = 1; \
+ } else if (__ac_isdel(h->flags, x)) { /* deleted */ \
+ h->keys[x] = key; \
+ __ac_set_isboth_false(h->flags, x); \
+ ++h->size; \
+ *ret = 2; \
+ } else *ret = 0; /* Don't touch h->keys[x] if present and not deleted */ \
+ return x; \
+ } \
+ SCOPE void kh_del_##name(kh_##name##_t *h, khint_t x) \
+ { \
+ if (x != h->n_buckets && !__ac_iseither(h->flags, x)) { \
+ __ac_set_isdel_true(h->flags, x); \
+ --h->size; \
+ } \
+ }
+
+#define KHASH_DECLARE(name, khkey_t, khval_t) \
+ __KHASH_TYPE(name, khkey_t, khval_t) \
+ __KHASH_PROTOTYPES(name, khkey_t, khval_t)
+
+#define KHASH_INIT2(name, SCOPE, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal) \
+ __KHASH_TYPE(name, khkey_t, khval_t) \
+ __KHASH_IMPL(name, SCOPE, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal)
+
+#define KHASH_INIT(name, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal) \
+ KHASH_INIT2(name, static kh_inline klib_unused, khkey_t, khval_t, kh_is_map, __hash_func, __hash_equal)
+
+/* --- BEGIN OF HASH FUNCTIONS --- */
+
+/*! @function
+ @abstract Integer hash function
+ @param key The integer [khint32_t]
+ @return The hash value [khint_t]
+ */
+#define kh_int_hash_func(key) (khint32_t)(key)
+/*! @function
+ @abstract Integer comparison function
+ */
+#define kh_int_hash_equal(a, b) ((a) == (b))
+/*! @function
+ @abstract 64-bit integer hash function
+ @param key The integer [khint64_t]
+ @return The hash value [khint_t]
+ */
+#define kh_int64_hash_func(key) (khint32_t)((key)>>33^(key)^(key)<<11)
+/*! @function
+ @abstract 64-bit integer comparison function
+ */
+#define kh_int64_hash_equal(a, b) ((a) == (b))
+/*! @function
+ @abstract const char* hash function
+ @param s Pointer to a null terminated string
+ @return The hash value
+ */
+static kh_inline khint_t __ac_X31_hash_string(const char *s)
+{
+ khint_t h = (khint_t)*s;
+ if (h) for (++s ; *s; ++s) h = (h << 5) - h + (khint_t)*s;
+ return h;
+}
+/*! @function
+ @abstract Another interface to const char* hash function
+ @param key Pointer to a null terminated string [const char*]
+ @return The hash value [khint_t]
+ */
+#define kh_str_hash_func(key) __ac_X31_hash_string(key)
+/*! @function
+ @abstract Const char* comparison function
+ */
+#define kh_str_hash_equal(a, b) (strcmp(a, b) == 0)
+
+static kh_inline khint_t __ac_Wang_hash(khint_t key)
+{
+ key += ~(key << 15);
+ key ^= (key >> 10);
+ key += (key << 3);
+ key ^= (key >> 6);
+ key += ~(key << 11);
+ key ^= (key >> 16);
+ return key;
+}
+#define kh_int_hash_func2(k) __ac_Wang_hash((khint_t)key)
+
+/* --- END OF HASH FUNCTIONS --- */
+
+/* Other convenient macros... */
+
+/*!
+ @abstract Type of the hash table.
+ @param name Name of the hash table [symbol]
+ */
+#define khash_t(name) kh_##name##_t
+
+/*! @function
+ @abstract Initiate a hash table.
+ @param name Name of the hash table [symbol]
+ @return Pointer to the hash table [khash_t(name)*]
+ */
+#define kh_init(name) kh_init_##name()
+
+/*! @function
+ @abstract Destroy a hash table.
+ @param name Name of the hash table [symbol]
+ @param h Pointer to the hash table [khash_t(name)*]
+ */
+#define kh_destroy(name, h) kh_destroy_##name(h)
+
+/*! @function
+ @abstract Reset a hash table without deallocating memory.
+ @param name Name of the hash table [symbol]
+ @param h Pointer to the hash table [khash_t(name)*]
+ */
+#define kh_clear(name, h) kh_clear_##name(h)
+
+/*! @function
+ @abstract Resize a hash table.
+ @param name Name of the hash table [symbol]
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param s New size [khint_t]
+ */
+#define kh_resize(name, h, s) kh_resize_##name(h, s)
+
+/*! @function
+ @abstract Insert a key to the hash table.
+ @param name Name of the hash table [symbol]
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param k Key [type of keys]
+ @param r Extra return code: -1 if the operation failed;
+ 0 if the key is present in the hash table;
+ 1 if the bucket is empty (never used); 2 if the element in
+ the bucket has been deleted [int*]
+ @return Iterator to the inserted element [khint_t]
+ */
+#define kh_put(name, h, k, r) kh_put_##name(h, k, r)
+
+/*! @function
+ @abstract Retrieve a key from the hash table.
+ @param name Name of the hash table [symbol]
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param k Key [type of keys]
+ @return Iterator to the found element, or kh_end(h) if the element is absent [khint_t]
+ */
+#define kh_get(name, h, k) kh_get_##name(h, k)
+
+/*! @function
+ @abstract Remove a key from the hash table.
+ @param name Name of the hash table [symbol]
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param k Iterator to the element to be deleted [khint_t]
+ */
+#define kh_del(name, h, k) kh_del_##name(h, k)
+
+/*! @function
+ @abstract Test whether a bucket contains data.
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param x Iterator to the bucket [khint_t]
+ @return 1 if containing data; 0 otherwise [int]
+ */
+#define kh_exist(h, x) (!__ac_iseither((h)->flags, (x)))
+
+/*! @function
+ @abstract Get key given an iterator
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param x Iterator to the bucket [khint_t]
+ @return Key [type of keys]
+ */
+#define kh_key(h, x) ((h)->keys[x])
+
+/*! @function
+ @abstract Get value given an iterator
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param x Iterator to the bucket [khint_t]
+ @return Value [type of values]
+ @discussion For hash sets, calling this results in segfault.
+ */
+#define kh_val(h, x) ((h)->vals[x])
+
+/*! @function
+ @abstract Alias of kh_val()
+ */
+#define kh_value(h, x) ((h)->vals[x])
+
+/*! @function
+ @abstract Get the start iterator
+ @param h Pointer to the hash table [khash_t(name)*]
+ @return The start iterator [khint_t]
+ */
+#define kh_begin(h) (khint_t)(0)
+
+/*! @function
+ @abstract Get the end iterator
+ @param h Pointer to the hash table [khash_t(name)*]
+ @return The end iterator [khint_t]
+ */
+#define kh_end(h) ((h)->n_buckets)
+
+/*! @function
+ @abstract Get the number of elements in the hash table
+ @param h Pointer to the hash table [khash_t(name)*]
+ @return Number of elements in the hash table [khint_t]
+ */
+#define kh_size(h) ((h)->size)
+
+/*! @function
+ @abstract Get the number of buckets in the hash table
+ @param h Pointer to the hash table [khash_t(name)*]
+ @return Number of buckets in the hash table [khint_t]
+ */
+#define kh_n_buckets(h) ((h)->n_buckets)
+
+/*! @function
+ @abstract Iterate over the entries in the hash table
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param kvar Variable to which key will be assigned
+ @param vvar Variable to which value will be assigned
+ @param code Block of code to execute
+ */
+#define kh_foreach(h, kvar, vvar, code) { khint_t __i; \
+ for (__i = kh_begin(h); __i != kh_end(h); ++__i) { \
+ if (!kh_exist(h,__i)) continue; \
+ (kvar) = kh_key(h,__i); \
+ (vvar) = kh_val(h,__i); \
+ code; \
+ } }
+
+/*! @function
+ @abstract Iterate over the values in the hash table
+ @param h Pointer to the hash table [khash_t(name)*]
+ @param vvar Variable to which value will be assigned
+ @param code Block of code to execute
+ */
+#define kh_foreach_value(h, vvar, code) { khint_t __i; \
+ for (__i = kh_begin(h); __i != kh_end(h); ++__i) { \
+ if (!kh_exist(h,__i)) continue; \
+ (vvar) = kh_val(h,__i); \
+ code; \
+ } }
+
+/* More conenient interfaces */
+
+/*! @function
+ @abstract Instantiate a hash set containing integer keys
+ @param name Name of the hash table [symbol]
+ */
+#define KHASH_SET_INIT_INT(name) \
+ KHASH_INIT(name, khint32_t, char, 0, kh_int_hash_func, kh_int_hash_equal)
+
+/*! @function
+ @abstract Instantiate a hash map containing integer keys
+ @param name Name of the hash table [symbol]
+ @param khval_t Type of values [type]
+ */
+#define KHASH_MAP_INIT_INT(name, khval_t) \
+ KHASH_INIT(name, khint32_t, khval_t, 1, kh_int_hash_func, kh_int_hash_equal)
+
+/*! @function
+ @abstract Instantiate a hash map containing 64-bit integer keys
+ @param name Name of the hash table [symbol]
+ */
+#define KHASH_SET_INIT_INT64(name) \
+ KHASH_INIT(name, khint64_t, char, 0, kh_int64_hash_func, kh_int64_hash_equal)
+
+/*! @function
+ @abstract Instantiate a hash map containing 64-bit integer keys
+ @param name Name of the hash table [symbol]
+ @param khval_t Type of values [type]
+ */
+#define KHASH_MAP_INIT_INT64(name, khval_t) \
+ KHASH_INIT(name, khint64_t, khval_t, 1, kh_int64_hash_func, kh_int64_hash_equal)
+
+typedef const char *kh_cstr_t;
+/*! @function
+ @abstract Instantiate a hash map containing const char* keys
+ @param name Name of the hash table [symbol]
+ */
+#define KHASH_SET_INIT_STR(name) \
+ KHASH_INIT(name, kh_cstr_t, char, 0, kh_str_hash_func, kh_str_hash_equal)
+
+/*! @function
+ @abstract Instantiate a hash map containing const char* keys
+ @param name Name of the hash table [symbol]
+ @param khval_t Type of values [type]
+ */
+#define KHASH_MAP_INIT_STR(name, khval_t) \
+ KHASH_INIT(name, kh_cstr_t, khval_t, 1, kh_str_hash_func, kh_str_hash_equal)
+
+#endif /* __AC_KHASH_H */
--- /dev/null
+/* khash_str2int.h -- C-string to integer hash table.
+
+ Copyright (C) 2013 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_KHASH_STR2INT_H
+#define HTSLIB_KHASH_STR2INT_H
+
+#include <htslib/khash.h>
+
+KHASH_MAP_INIT_STR(str2int, int)
+
+/*
+ * Wrappers for khash dictionaries used by mpileup.
+ */
+
+static inline void *khash_str2int_init(void)
+{
+ return kh_init(str2int);
+}
+
+/*
+ * Destroy the hash structure, but not the keys
+ */
+static inline void khash_str2int_destroy(void *_hash)
+{
+ khash_t(str2int) *hash = (khash_t(str2int)*)_hash;
+ if (hash) kh_destroy(str2int, hash); // Note that strings are not freed.
+}
+
+/*
+ * Destroys both the hash structure and the keys
+ */
+static inline void khash_str2int_destroy_free(void *_hash)
+{
+ khash_t(str2int) *hash = (khash_t(str2int)*)_hash;
+ khint_t k;
+ if (hash == 0) return;
+ for (k = 0; k < kh_end(hash); ++k)
+ if (kh_exist(hash, k)) free((char*)kh_key(hash, k));
+ kh_destroy(str2int, hash);
+}
+
+/*
+ * Returns 1 if key exists or 0 if not
+ */
+static inline int khash_str2int_has_key(void *_hash, const char *str)
+{
+ khash_t(str2int) *hash = (khash_t(str2int)*)_hash;
+ khint_t k = kh_get(str2int, hash, str);
+ if ( k == kh_end(hash) ) return 0;
+ return 1;
+}
+
+/*
+ * Returns 0 on success and -1 when the key is not present. On success,
+ * *value is set, unless NULL is passed.
+ */
+static inline int khash_str2int_get(void *_hash, const char *str, int *value)
+{
+ khash_t(str2int) *hash = (khash_t(str2int)*)_hash;
+ khint_t k;
+ if ( !hash ) return -1;
+ k = kh_get(str2int, hash, str);
+ if ( k == kh_end(hash) ) return -1;
+ if ( !value ) return 0;
+ *value = kh_val(hash, k);
+ return 0;
+}
+
+/*
+ * Add a new string to the dictionary, auto-incrementing the value.
+ * On success returns the newly inserted integer id, on error -1
+ * is returned. Note that the key must continue to exist throughout
+ * the whole life of _hash.
+ */
+static inline int khash_str2int_inc(void *_hash, const char *str)
+{
+ khint_t k;
+ int ret;
+ khash_t(str2int) *hash = (khash_t(str2int)*)_hash;
+ if ( !hash ) return -1;
+ k = kh_put(str2int, hash, str, &ret);
+ if (ret == 0) return kh_val(hash, k);
+ kh_val(hash, k) = kh_size(hash) - 1;
+ return kh_val(hash, k);
+}
+
+/*
+ * Set a new key,value pair. On success returns the bin index, on
+ * error -1 is returned. Note that the key must contnue to exist
+ * throughout the whole life of _hash.
+ */
+static inline int khash_str2int_set(void *_hash, const char *str, int value)
+{
+ khint_t k;
+ int ret;
+ khash_t(str2int) *hash = (khash_t(str2int)*)_hash;
+ if ( !hash ) return -1;
+ k = kh_put(str2int, hash, str, &ret);
+ kh_val(hash,k) = value;
+ return k;
+}
+
+/*
+ * Return the number of keys in the hash table.
+ */
+static inline int khash_str2int_size(void *_hash)
+{
+ khash_t(str2int) *hash = (khash_t(str2int)*)_hash;
+ return kh_size(hash);
+}
+
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (c) 2008-2009, by Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+#ifndef _AC_KLIST_H
+#define _AC_KLIST_H
+
+#include <stdlib.h>
+
+#ifndef klib_unused
+#if (defined __clang__ && __clang_major__ >= 3) || (defined __GNUC__ && __GNUC__ >= 3)
+#define klib_unused __attribute__ ((__unused__))
+#else
+#define klib_unused
+#endif
+#endif /* klib_unused */
+
+#define KMEMPOOL_INIT2(SCOPE, name, kmptype_t, kmpfree_f) \
+ typedef struct { \
+ size_t cnt, n, max; \
+ kmptype_t **buf; \
+ } kmp_##name##_t; \
+ SCOPE kmp_##name##_t *kmp_init_##name(void) { \
+ return calloc(1, sizeof(kmp_##name##_t)); \
+ } \
+ SCOPE void kmp_destroy_##name(kmp_##name##_t *mp) { \
+ size_t k; \
+ for (k = 0; k < mp->n; ++k) { \
+ kmpfree_f(mp->buf[k]); free(mp->buf[k]); \
+ } \
+ free(mp->buf); free(mp); \
+ } \
+ SCOPE kmptype_t *kmp_alloc_##name(kmp_##name##_t *mp) { \
+ ++mp->cnt; \
+ if (mp->n == 0) return calloc(1, sizeof(kmptype_t)); \
+ return mp->buf[--mp->n]; \
+ } \
+ SCOPE void kmp_free_##name(kmp_##name##_t *mp, kmptype_t *p) { \
+ --mp->cnt; \
+ if (mp->n == mp->max) { \
+ mp->max = mp->max? mp->max<<1 : 16; \
+ mp->buf = realloc(mp->buf, sizeof(kmptype_t *) * mp->max); \
+ } \
+ mp->buf[mp->n++] = p; \
+ }
+
+#define KMEMPOOL_INIT(name, kmptype_t, kmpfree_f) \
+ KMEMPOOL_INIT2(static inline klib_unused, name, kmptype_t, kmpfree_f)
+
+#define kmempool_t(name) kmp_##name##_t
+#define kmp_init(name) kmp_init_##name()
+#define kmp_destroy(name, mp) kmp_destroy_##name(mp)
+#define kmp_alloc(name, mp) kmp_alloc_##name(mp)
+#define kmp_free(name, mp, p) kmp_free_##name(mp, p)
+
+#define KLIST_INIT2(SCOPE, name, kltype_t, kmpfree_t) \
+ struct __kl1_##name { \
+ kltype_t data; \
+ struct __kl1_##name *next; \
+ }; \
+ typedef struct __kl1_##name kl1_##name; \
+ KMEMPOOL_INIT2(SCOPE, name, kl1_##name, kmpfree_t) \
+ typedef struct { \
+ kl1_##name *head, *tail; \
+ kmp_##name##_t *mp; \
+ size_t size; \
+ } kl_##name##_t; \
+ SCOPE kl_##name##_t *kl_init_##name(void) { \
+ kl_##name##_t *kl = calloc(1, sizeof(kl_##name##_t)); \
+ kl->mp = kmp_init(name); \
+ kl->head = kl->tail = kmp_alloc(name, kl->mp); \
+ kl->head->next = 0; \
+ return kl; \
+ } \
+ SCOPE void kl_destroy_##name(kl_##name##_t *kl) { \
+ kl1_##name *p; \
+ for (p = kl->head; p != kl->tail; p = p->next) \
+ kmp_free(name, kl->mp, p); \
+ kmp_free(name, kl->mp, p); \
+ kmp_destroy(name, kl->mp); \
+ free(kl); \
+ } \
+ SCOPE kltype_t *kl_pushp_##name(kl_##name##_t *kl) { \
+ kl1_##name *q, *p = kmp_alloc(name, kl->mp); \
+ q = kl->tail; p->next = 0; kl->tail->next = p; kl->tail = p; \
+ ++kl->size; \
+ return &q->data; \
+ } \
+ SCOPE int kl_shift_##name(kl_##name##_t *kl, kltype_t *d) { \
+ kl1_##name *p; \
+ if (kl->head->next == 0) return -1; \
+ --kl->size; \
+ p = kl->head; kl->head = kl->head->next; \
+ if (d) *d = p->data; \
+ kmp_free(name, kl->mp, p); \
+ return 0; \
+ }
+
+#define KLIST_INIT(name, kltype_t, kmpfree_t) \
+ KLIST_INIT2(static inline klib_unused, name, kltype_t, kmpfree_t)
+
+#define kliter_t(name) kl1_##name
+#define klist_t(name) kl_##name##_t
+#define kl_val(iter) ((iter)->data)
+#define kl_next(iter) ((iter)->next)
+#define kl_begin(kl) ((kl)->head)
+#define kl_end(kl) ((kl)->tail)
+
+#define kl_init(name) kl_init_##name()
+#define kl_destroy(name, kl) kl_destroy_##name(kl)
+#define kl_pushp(name, kl) kl_pushp_##name(kl)
+#define kl_shift(name, kl, d) kl_shift_##name(kl, d)
+
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (c) 2008 by Genome Research Ltd (GRL).
+ 2010 by Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+#ifndef KNETFILE_H
+#define KNETFILE_H
+
+#include <stdint.h>
+#include <fcntl.h>
+
+#ifndef _WIN32
+#define netread(fd, ptr, len) read(fd, ptr, len)
+#define netwrite(fd, ptr, len) write(fd, ptr, len)
+#define netclose(fd) close(fd)
+#else
+#include <winsock2.h>
+#define netread(fd, ptr, len) recv(fd, ptr, len, 0)
+#define netwrite(fd, ptr, len) send(fd, ptr, len, 0)
+#define netclose(fd) closesocket(fd)
+#endif
+
+// FIXME: currently I/O is unbuffered
+
+#define KNF_TYPE_LOCAL 1
+#define KNF_TYPE_FTP 2
+#define KNF_TYPE_HTTP 3
+
+typedef struct knetFile_s {
+ int type, fd;
+ int64_t offset;
+ char *host, *port;
+
+ // the following are for FTP only
+ int ctrl_fd, pasv_ip[4], pasv_port, max_response, no_reconnect, is_ready;
+ char *response, *retr, *size_cmd;
+ int64_t seek_offset; // for lazy seek
+ int64_t file_size;
+
+ // the following are for HTTP only
+ char *path, *http_host;
+} knetFile;
+
+#define knet_tell(fp) ((fp)->offset)
+#define knet_fileno(fp) ((fp)->fd)
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+#ifdef _WIN32
+ int knet_win32_init();
+ void knet_win32_destroy();
+#endif
+
+ knetFile *knet_open(const char *fn, const char *mode);
+
+ /*
+ This only works with local files.
+ */
+ knetFile *knet_dopen(int fd, const char *mode);
+
+ /*
+ If ->is_ready==0, this routine updates ->fd; otherwise, it simply
+ reads from ->fd.
+ */
+ ssize_t knet_read(knetFile *fp, void *buf, size_t len);
+
+ /*
+ This routine only sets ->offset and ->is_ready=0. It does not
+ communicate with the FTP server.
+ */
+ off_t knet_seek(knetFile *fp, off_t off, int whence);
+ int knet_close(knetFile *fp);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (c) 2008, 2009, 2011 Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+/* Last Modified: 05MAR2012 */
+
+#ifndef AC_KSEQ_H
+#define AC_KSEQ_H
+
+#include <ctype.h>
+#include <string.h>
+#include <stdlib.h>
+
+#define KS_SEP_SPACE 0 // isspace(): \t, \n, \v, \f, \r
+#define KS_SEP_TAB 1 // isspace() && !' '
+#define KS_SEP_LINE 2 // line separator: "\n" (Unix) or "\r\n" (Windows)
+#define KS_SEP_MAX 2
+
+#define __KS_TYPE(type_t) \
+ typedef struct __kstream_t { \
+ int begin, end; \
+ int is_eof:2, bufsize:30; \
+ uint64_t seek_pos; \
+ type_t f; \
+ unsigned char *buf; \
+ } kstream_t;
+
+#define ks_eof(ks) ((ks)->is_eof && (ks)->begin >= (ks)->end)
+#define ks_rewind(ks) ((ks)->is_eof = (ks)->begin = (ks)->end = 0)
+
+#define __KS_BASIC(SCOPE, type_t, __bufsize) \
+ SCOPE kstream_t *ks_init(type_t f) \
+ { \
+ kstream_t *ks = (kstream_t*)calloc(1, sizeof(kstream_t)); \
+ ks->f = f; ks->bufsize = __bufsize; \
+ ks->buf = (unsigned char*)malloc(__bufsize); \
+ return ks; \
+ } \
+ SCOPE void ks_destroy(kstream_t *ks) \
+ { \
+ if (!ks) return; \
+ free(ks->buf); \
+ free(ks); \
+ }
+
+#define __KS_INLINED(__read) \
+ static inline int ks_getc(kstream_t *ks) \
+ { \
+ if (ks->is_eof && ks->begin >= ks->end) return -1; \
+ if (ks->begin >= ks->end) { \
+ ks->begin = 0; \
+ ks->end = __read(ks->f, ks->buf, ks->bufsize); \
+ if (ks->end == 0) { ks->is_eof = 1; return -1; } \
+ } \
+ ks->seek_pos++; \
+ return (int)ks->buf[ks->begin++]; \
+ } \
+ static inline int ks_getuntil(kstream_t *ks, int delimiter, kstring_t *str, int *dret) \
+ { return ks_getuntil2(ks, delimiter, str, dret, 0); }
+
+#ifndef KSTRING_T
+#define KSTRING_T kstring_t
+typedef struct __kstring_t {
+ size_t l, m;
+ char *s;
+} kstring_t;
+#endif
+
+#ifndef kroundup32
+#define kroundup32(x) (--(x), (x)|=(x)>>1, (x)|=(x)>>2, (x)|=(x)>>4, (x)|=(x)>>8, (x)|=(x)>>16, ++(x))
+#endif
+
+#define __KS_GETUNTIL(SCOPE, __read) \
+ SCOPE int ks_getuntil2(kstream_t *ks, int delimiter, kstring_t *str, int *dret, int append) \
+ { \
+ int gotany = 0; \
+ if (dret) *dret = 0; \
+ str->l = append? str->l : 0; \
+ uint64_t seek_pos = str->l; \
+ for (;;) { \
+ int i; \
+ if (ks->begin >= ks->end) { \
+ if (!ks->is_eof) { \
+ ks->begin = 0; \
+ ks->end = __read(ks->f, ks->buf, ks->bufsize); \
+ if (ks->end == 0) { ks->is_eof = 1; break; } \
+ } else break; \
+ } \
+ if (delimiter == KS_SEP_LINE) { \
+ for (i = ks->begin; i < ks->end; ++i) \
+ if (ks->buf[i] == '\n') break; \
+ } else if (delimiter > KS_SEP_MAX) { \
+ for (i = ks->begin; i < ks->end; ++i) \
+ if (ks->buf[i] == delimiter) break; \
+ } else if (delimiter == KS_SEP_SPACE) { \
+ for (i = ks->begin; i < ks->end; ++i) \
+ if (isspace(ks->buf[i])) break; \
+ } else if (delimiter == KS_SEP_TAB) { \
+ for (i = ks->begin; i < ks->end; ++i) \
+ if (isspace(ks->buf[i]) && ks->buf[i] != ' ') break; \
+ } else i = 0; /* never come to here! */ \
+ if (str->m - str->l < (size_t)(i - ks->begin + 1)) { \
+ str->m = str->l + (i - ks->begin) + 1; \
+ kroundup32(str->m); \
+ str->s = (char*)realloc(str->s, str->m); \
+ } \
+ seek_pos += i - ks->begin; if ( i < ks->end ) seek_pos++; \
+ gotany = 1; \
+ memcpy(str->s + str->l, ks->buf + ks->begin, i - ks->begin); \
+ str->l = str->l + (i - ks->begin); \
+ ks->begin = i + 1; \
+ if (i < ks->end) { \
+ if (dret) *dret = ks->buf[i]; \
+ break; \
+ } \
+ } \
+ if (!gotany && ks_eof(ks)) return -1; \
+ ks->seek_pos += seek_pos; \
+ if (str->s == 0) { \
+ str->m = 1; \
+ str->s = (char*)calloc(1, 1); \
+ } else if (delimiter == KS_SEP_LINE && str->l > 1 && str->s[str->l-1] == '\r') --str->l; \
+ str->s[str->l] = '\0'; \
+ return str->l; \
+ }
+
+#define KSTREAM_INIT2(SCOPE, type_t, __read, __bufsize) \
+ __KS_TYPE(type_t) \
+ __KS_BASIC(SCOPE, type_t, __bufsize) \
+ __KS_GETUNTIL(SCOPE, __read) \
+ __KS_INLINED(__read)
+
+#define KSTREAM_INIT(type_t, __read, __bufsize) KSTREAM_INIT2(static, type_t, __read, __bufsize)
+
+#define KSTREAM_DECLARE(type_t, __read) \
+ __KS_TYPE(type_t) \
+ extern int ks_getuntil2(kstream_t *ks, int delimiter, kstring_t *str, int *dret, int append); \
+ extern kstream_t *ks_init(type_t f); \
+ extern void ks_destroy(kstream_t *ks); \
+ __KS_INLINED(__read)
+
+/******************
+ * FASTA/Q parser *
+ ******************/
+
+#define kseq_rewind(ks) ((ks)->last_char = (ks)->f->is_eof = (ks)->f->begin = (ks)->f->end = 0)
+
+#define __KSEQ_BASIC(SCOPE, type_t) \
+ SCOPE kseq_t *kseq_init(type_t fd) \
+ { \
+ kseq_t *s = (kseq_t*)calloc(1, sizeof(kseq_t)); \
+ s->f = ks_init(fd); \
+ return s; \
+ } \
+ SCOPE void kseq_destroy(kseq_t *ks) \
+ { \
+ if (!ks) return; \
+ free(ks->name.s); free(ks->comment.s); free(ks->seq.s); free(ks->qual.s); \
+ ks_destroy(ks->f); \
+ free(ks); \
+ }
+
+/* Return value:
+ >=0 length of the sequence (normal)
+ -1 end-of-file
+ -2 truncated quality string
+ */
+#define __KSEQ_READ(SCOPE) \
+ SCOPE int kseq_read(kseq_t *seq) \
+ { \
+ int c; \
+ kstream_t *ks = seq->f; \
+ if (seq->last_char == 0) { /* then jump to the next header line */ \
+ while ((c = ks_getc(ks)) != -1 && c != '>' && c != '@'); \
+ if (c == -1) return -1; /* end of file */ \
+ seq->last_char = c; \
+ } /* else: the first header char has been read in the previous call */ \
+ seq->comment.l = seq->seq.l = seq->qual.l = 0; /* reset all members */ \
+ if (ks_getuntil(ks, 0, &seq->name, &c) < 0) return -1; /* normal exit: EOF */ \
+ if (c != '\n') ks_getuntil(ks, KS_SEP_LINE, &seq->comment, 0); /* read FASTA/Q comment */ \
+ if (seq->seq.s == 0) { /* we can do this in the loop below, but that is slower */ \
+ seq->seq.m = 256; \
+ seq->seq.s = (char*)malloc(seq->seq.m); \
+ } \
+ while ((c = ks_getc(ks)) != -1 && c != '>' && c != '+' && c != '@') { \
+ if (c == '\n') continue; /* skip empty lines */ \
+ seq->seq.s[seq->seq.l++] = c; /* this is safe: we always have enough space for 1 char */ \
+ ks_getuntil2(ks, KS_SEP_LINE, &seq->seq, 0, 1); /* read the rest of the line */ \
+ } \
+ if (c == '>' || c == '@') seq->last_char = c; /* the first header char has been read */ \
+ if (seq->seq.l + 1 >= seq->seq.m) { /* seq->seq.s[seq->seq.l] below may be out of boundary */ \
+ seq->seq.m = seq->seq.l + 2; \
+ kroundup32(seq->seq.m); /* rounded to the next closest 2^k */ \
+ seq->seq.s = (char*)realloc(seq->seq.s, seq->seq.m); \
+ } \
+ seq->seq.s[seq->seq.l] = 0; /* null terminated string */ \
+ if (c != '+') return seq->seq.l; /* FASTA */ \
+ if (seq->qual.m < seq->seq.m) { /* allocate memory for qual in case insufficient */ \
+ seq->qual.m = seq->seq.m; \
+ seq->qual.s = (char*)realloc(seq->qual.s, seq->qual.m); \
+ } \
+ while ((c = ks_getc(ks)) != -1 && c != '\n'); /* skip the rest of '+' line */ \
+ if (c == -1) return -2; /* error: no quality string */ \
+ while (ks_getuntil2(ks, KS_SEP_LINE, &seq->qual, 0, 1) >= 0 && seq->qual.l < seq->seq.l); \
+ seq->last_char = 0; /* we have not come to the next header line */ \
+ if (seq->seq.l != seq->qual.l) return -2; /* error: qual string is of a different length */ \
+ return seq->seq.l; \
+ }
+
+#define __KSEQ_TYPE(type_t) \
+ typedef struct { \
+ kstring_t name, comment, seq, qual; \
+ int last_char; \
+ kstream_t *f; \
+ } kseq_t;
+
+#define KSEQ_INIT2(SCOPE, type_t, __read) \
+ KSTREAM_INIT(type_t, __read, 16384) \
+ __KSEQ_TYPE(type_t) \
+ __KSEQ_BASIC(SCOPE, type_t) \
+ __KSEQ_READ(SCOPE)
+
+#define KSEQ_INIT(type_t, __read) KSEQ_INIT2(static, type_t, __read)
+
+#define KSEQ_DECLARE(type_t) \
+ __KS_TYPE(type_t) \
+ __KSEQ_TYPE(type_t) \
+ extern kseq_t *kseq_init(type_t fd); \
+ void kseq_destroy(kseq_t *ks); \
+ int kseq_read(kseq_t *seq);
+
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (c) 2008 Genome Research Ltd (GRL).
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+/* Contact: Heng Li <lh3@sanger.ac.uk> */
+
+/*
+ 2012-12-11 (0.1.4):
+
+ * Defined __ks_insertsort_##name as static to compile with C99.
+
+ 2008-11-16 (0.1.4):
+
+ * Fixed a bug in introsort() that happens in rare cases.
+
+ 2008-11-05 (0.1.3):
+
+ * Fixed a bug in introsort() for complex comparisons.
+
+ * Fixed a bug in mergesort(). The previous version is not stable.
+
+ 2008-09-15 (0.1.2):
+
+ * Accelerated introsort. On my Mac (not on another Linux machine),
+ my implementation is as fast as std::sort on random input.
+
+ * Added combsort and in introsort, switch to combsort if the
+ recursion is too deep.
+
+ 2008-09-13 (0.1.1):
+
+ * Added k-small algorithm
+
+ 2008-09-05 (0.1.0):
+
+ * Initial version
+
+*/
+
+#ifndef AC_KSORT_H
+#define AC_KSORT_H
+
+#include <stdlib.h>
+#include <string.h>
+
+typedef struct {
+ void *left, *right;
+ int depth;
+} ks_isort_stack_t;
+
+#define KSORT_SWAP(type_t, a, b) { register type_t t=(a); (a)=(b); (b)=t; }
+
+#define KSORT_INIT(name, type_t, __sort_lt) \
+ void ks_mergesort_##name(size_t n, type_t array[], type_t temp[]) \
+ { \
+ type_t *a2[2], *a, *b; \
+ int curr, shift; \
+ \
+ a2[0] = array; \
+ a2[1] = temp? temp : (type_t*)malloc(sizeof(type_t) * n); \
+ for (curr = 0, shift = 0; (1ul<<shift) < n; ++shift) { \
+ a = a2[curr]; b = a2[1-curr]; \
+ if (shift == 0) { \
+ type_t *p = b, *i, *eb = a + n; \
+ for (i = a; i < eb; i += 2) { \
+ if (i == eb - 1) *p++ = *i; \
+ else { \
+ if (__sort_lt(*(i+1), *i)) { \
+ *p++ = *(i+1); *p++ = *i; \
+ } else { \
+ *p++ = *i; *p++ = *(i+1); \
+ } \
+ } \
+ } \
+ } else { \
+ size_t i, step = 1ul<<shift; \
+ for (i = 0; i < n; i += step<<1) { \
+ type_t *p, *j, *k, *ea, *eb; \
+ if (n < i + step) { \
+ ea = a + n; eb = a; \
+ } else { \
+ ea = a + i + step; \
+ eb = a + (n < i + (step<<1)? n : i + (step<<1)); \
+ } \
+ j = a + i; k = a + i + step; p = b + i; \
+ while (j < ea && k < eb) { \
+ if (__sort_lt(*k, *j)) *p++ = *k++; \
+ else *p++ = *j++; \
+ } \
+ while (j < ea) *p++ = *j++; \
+ while (k < eb) *p++ = *k++; \
+ } \
+ } \
+ curr = 1 - curr; \
+ } \
+ if (curr == 1) { \
+ type_t *p = a2[0], *i = a2[1], *eb = array + n; \
+ for (; p < eb; ++i) *p++ = *i; \
+ } \
+ if (temp == 0) free(a2[1]); \
+ } \
+ void ks_heapadjust_##name(size_t i, size_t n, type_t l[]) \
+ { \
+ size_t k = i; \
+ type_t tmp = l[i]; \
+ while ((k = (k << 1) + 1) < n) { \
+ if (k != n - 1 && __sort_lt(l[k], l[k+1])) ++k; \
+ if (__sort_lt(l[k], tmp)) break; \
+ l[i] = l[k]; i = k; \
+ } \
+ l[i] = tmp; \
+ } \
+ void ks_heapmake_##name(size_t lsize, type_t l[]) \
+ { \
+ size_t i; \
+ for (i = (lsize >> 1) - 1; i != (size_t)(-1); --i) \
+ ks_heapadjust_##name(i, lsize, l); \
+ } \
+ void ks_heapsort_##name(size_t lsize, type_t l[]) \
+ { \
+ size_t i; \
+ for (i = lsize - 1; i > 0; --i) { \
+ type_t tmp; \
+ tmp = *l; *l = l[i]; l[i] = tmp; ks_heapadjust_##name(0, i, l); \
+ } \
+ } \
+ static inline void __ks_insertsort_##name(type_t *s, type_t *t) \
+ { \
+ type_t *i, *j, swap_tmp; \
+ for (i = s + 1; i < t; ++i) \
+ for (j = i; j > s && __sort_lt(*j, *(j-1)); --j) { \
+ swap_tmp = *j; *j = *(j-1); *(j-1) = swap_tmp; \
+ } \
+ } \
+ void ks_combsort_##name(size_t n, type_t a[]) \
+ { \
+ const double shrink_factor = 1.2473309501039786540366528676643; \
+ int do_swap; \
+ size_t gap = n; \
+ type_t tmp, *i, *j; \
+ do { \
+ if (gap > 2) { \
+ gap = (size_t)(gap / shrink_factor); \
+ if (gap == 9 || gap == 10) gap = 11; \
+ } \
+ do_swap = 0; \
+ for (i = a; i < a + n - gap; ++i) { \
+ j = i + gap; \
+ if (__sort_lt(*j, *i)) { \
+ tmp = *i; *i = *j; *j = tmp; \
+ do_swap = 1; \
+ } \
+ } \
+ } while (do_swap || gap > 2); \
+ if (gap != 1) __ks_insertsort_##name(a, a + n); \
+ } \
+ void ks_introsort_##name(size_t n, type_t a[]) \
+ { \
+ int d; \
+ ks_isort_stack_t *top, *stack; \
+ type_t rp, swap_tmp; \
+ type_t *s, *t, *i, *j, *k; \
+ \
+ if (n < 1) return; \
+ else if (n == 2) { \
+ if (__sort_lt(a[1], a[0])) { swap_tmp = a[0]; a[0] = a[1]; a[1] = swap_tmp; } \
+ return; \
+ } \
+ for (d = 2; 1ul<<d < n; ++d); \
+ stack = (ks_isort_stack_t*)malloc(sizeof(ks_isort_stack_t) * ((sizeof(size_t)*d)+2)); \
+ top = stack; s = a; t = a + (n-1); d <<= 1; \
+ while (1) { \
+ if (s < t) { \
+ if (--d == 0) { \
+ ks_combsort_##name(t - s + 1, s); \
+ t = s; \
+ continue; \
+ } \
+ i = s; j = t; k = i + ((j-i)>>1) + 1; \
+ if (__sort_lt(*k, *i)) { \
+ if (__sort_lt(*k, *j)) k = j; \
+ } else k = __sort_lt(*j, *i)? i : j; \
+ rp = *k; \
+ if (k != t) { swap_tmp = *k; *k = *t; *t = swap_tmp; } \
+ for (;;) { \
+ do ++i; while (__sort_lt(*i, rp)); \
+ do --j; while (i <= j && __sort_lt(rp, *j)); \
+ if (j <= i) break; \
+ swap_tmp = *i; *i = *j; *j = swap_tmp; \
+ } \
+ swap_tmp = *i; *i = *t; *t = swap_tmp; \
+ if (i-s > t-i) { \
+ if (i-s > 16) { top->left = s; top->right = i-1; top->depth = d; ++top; } \
+ s = t-i > 16? i+1 : t; \
+ } else { \
+ if (t-i > 16) { top->left = i+1; top->right = t; top->depth = d; ++top; } \
+ t = i-s > 16? i-1 : s; \
+ } \
+ } else { \
+ if (top == stack) { \
+ free(stack); \
+ __ks_insertsort_##name(a, a+n); \
+ return; \
+ } else { --top; s = (type_t*)top->left; t = (type_t*)top->right; d = top->depth; } \
+ } \
+ } \
+ } \
+ /* This function is adapted from: http://ndevilla.free.fr/median/ */ \
+ /* 0 <= kk < n */ \
+ type_t ks_ksmall_##name(size_t n, type_t arr[], size_t kk) \
+ { \
+ type_t *low, *high, *k, *ll, *hh, *mid; \
+ low = arr; high = arr + n - 1; k = arr + kk; \
+ for (;;) { \
+ if (high <= low) return *k; \
+ if (high == low + 1) { \
+ if (__sort_lt(*high, *low)) KSORT_SWAP(type_t, *low, *high); \
+ return *k; \
+ } \
+ mid = low + (high - low) / 2; \
+ if (__sort_lt(*high, *mid)) KSORT_SWAP(type_t, *mid, *high); \
+ if (__sort_lt(*high, *low)) KSORT_SWAP(type_t, *low, *high); \
+ if (__sort_lt(*low, *mid)) KSORT_SWAP(type_t, *mid, *low); \
+ KSORT_SWAP(type_t, *mid, *(low+1)); \
+ ll = low + 1; hh = high; \
+ for (;;) { \
+ do ++ll; while (__sort_lt(*ll, *low)); \
+ do --hh; while (__sort_lt(*low, *hh)); \
+ if (hh < ll) break; \
+ KSORT_SWAP(type_t, *ll, *hh); \
+ } \
+ KSORT_SWAP(type_t, *low, *hh); \
+ if (hh <= k) low = ll; \
+ if (hh >= k) high = hh - 1; \
+ } \
+ } \
+ void ks_shuffle_##name(size_t n, type_t a[]) \
+ { \
+ int i, j; \
+ for (i = n; i > 1; --i) { \
+ type_t tmp; \
+ j = (int)(drand48() * i); \
+ tmp = a[j]; a[j] = a[i-1]; a[i-1] = tmp; \
+ } \
+ }
+
+#define ks_mergesort(name, n, a, t) ks_mergesort_##name(n, a, t)
+#define ks_introsort(name, n, a) ks_introsort_##name(n, a)
+#define ks_combsort(name, n, a) ks_combsort_##name(n, a)
+#define ks_heapsort(name, n, a) ks_heapsort_##name(n, a)
+#define ks_heapmake(name, n, a) ks_heapmake_##name(n, a)
+#define ks_heapadjust(name, i, n, a) ks_heapadjust_##name(i, n, a)
+#define ks_ksmall(name, n, a, k) ks_ksmall_##name(n, a, k)
+#define ks_shuffle(name, n, a) ks_shuffle_##name(n, a)
+
+#define ks_lt_generic(a, b) ((a) < (b))
+#define ks_lt_str(a, b) (strcmp((a), (b)) < 0)
+
+typedef const char *ksstr_t;
+
+#define KSORT_INIT_GENERIC(type_t) KSORT_INIT(type_t, type_t, ks_lt_generic)
+#define KSORT_INIT_STR KSORT_INIT(str, ksstr_t, ks_lt_str)
+
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (C) 2011 by Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+#ifndef KSTRING_H
+#define KSTRING_H
+
+#include <stdlib.h>
+#include <string.h>
+#include <stdarg.h>
+#include <stdint.h>
+#include <stdio.h>
+
+#ifndef kroundup32
+#define kroundup32(x) (--(x), (x)|=(x)>>1, (x)|=(x)>>2, (x)|=(x)>>4, (x)|=(x)>>8, (x)|=(x)>>16, ++(x))
+#endif
+
+#if defined __GNUC__ && (__GNUC__ > 2 || (__GNUC__ == 2 && __GNUC_MINOR__ > 4))
+#define KS_ATTR_PRINTF(fmt, arg) __attribute__((__format__ (__printf__, fmt, arg)))
+#else
+#define KS_ATTR_PRINTF(fmt, arg)
+#endif
+
+
+/* kstring_t is a simple non-opaque type whose fields are likely to be
+ * used directly by user code (but see also ks_str() and ks_len() below).
+ * A kstring_t object is initialised by either of
+ * kstring_t str = { 0, 0, NULL };
+ * kstring_t str; ...; str.l = str.m = 0; str.s = NULL;
+ * and either ownership of the underlying buffer should be given away before
+ * the object disappears (see ks_release() below) or the kstring_t should be
+ * destroyed with free(str.s); */
+#ifndef KSTRING_T
+#define KSTRING_T kstring_t
+typedef struct __kstring_t {
+ size_t l, m;
+ char *s;
+} kstring_t;
+#endif
+
+typedef struct {
+ uint64_t tab[4];
+ int sep, finished;
+ const char *p; // end of the current token
+} ks_tokaux_t;
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+ int kvsprintf(kstring_t *s, const char *fmt, va_list ap) KS_ATTR_PRINTF(2,0);
+ int ksprintf(kstring_t *s, const char *fmt, ...) KS_ATTR_PRINTF(2,3);
+ int ksplit_core(char *s, int delimiter, int *_max, int **_offsets);
+ char *kstrstr(const char *str, const char *pat, int **_prep);
+ char *kstrnstr(const char *str, const char *pat, int n, int **_prep);
+ void *kmemmem(const void *_str, int n, const void *_pat, int m, int **_prep);
+
+ /* kstrtok() is similar to strtok_r() except that str is not
+ * modified and both str and sep can be NULL. For efficiency, it is
+ * actually recommended to set both to NULL in the subsequent calls
+ * if sep is not changed. */
+ char *kstrtok(const char *str, const char *sep, ks_tokaux_t *aux);
+
+ /* kgetline() uses the supplied fgets()-like function to read a "\n"-
+ * or "\r\n"-terminated line from fp. The line read is appended to the
+ * kstring without its terminator and 0 is returned; EOF is returned at
+ * EOF or on error (determined by querying fp, as per fgets()). */
+ typedef char *kgets_func(char *, int, void *);
+ int kgetline(kstring_t *s, kgets_func *fgets, void *fp);
+
+#ifdef __cplusplus
+}
+#endif
+
+static inline int ks_resize(kstring_t *s, size_t size)
+{
+ if (s->m < size) {
+ char *tmp;
+ s->m = size;
+ kroundup32(s->m);
+ if ((tmp = (char*)realloc(s->s, s->m)))
+ s->s = tmp;
+ else
+ return -1;
+ }
+ return 0;
+}
+
+static inline char *ks_str(kstring_t *s)
+{
+ return s->s;
+}
+
+static inline size_t ks_len(kstring_t *s)
+{
+ return s->l;
+}
+
+// Give ownership of the underlying buffer away to something else (making
+// that something else responsible for freeing it), leaving the kstring_t
+// empty and ready to be used again, or ready to go out of scope without
+// needing free(str.s) to prevent a memory leak.
+static inline char *ks_release(kstring_t *s)
+{
+ char *ss = s->s;
+ s->l = s->m = 0;
+ s->s = NULL;
+ return ss;
+}
+
+static inline int kputsn(const char *p, int l, kstring_t *s)
+{
+ if (s->l + l + 1 >= s->m) {
+ char *tmp;
+ s->m = s->l + l + 2;
+ kroundup32(s->m);
+ if ((tmp = (char*)realloc(s->s, s->m)))
+ s->s = tmp;
+ else
+ return EOF;
+ }
+ memcpy(s->s + s->l, p, l);
+ s->l += l;
+ s->s[s->l] = 0;
+ return l;
+}
+
+static inline int kputs(const char *p, kstring_t *s)
+{
+ return kputsn(p, strlen(p), s);
+}
+
+static inline int kputc(int c, kstring_t *s)
+{
+ if (s->l + 1 >= s->m) {
+ char *tmp;
+ s->m = s->l + 2;
+ kroundup32(s->m);
+ if ((tmp = (char*)realloc(s->s, s->m)))
+ s->s = tmp;
+ else
+ return EOF;
+ }
+ s->s[s->l++] = c;
+ s->s[s->l] = 0;
+ return c;
+}
+
+static inline int kputc_(int c, kstring_t *s)
+{
+ if (s->l + 1 > s->m) {
+ char *tmp;
+ s->m = s->l + 1;
+ kroundup32(s->m);
+ if ((tmp = (char*)realloc(s->s, s->m)))
+ s->s = tmp;
+ else
+ return EOF;
+ }
+ s->s[s->l++] = c;
+ return 1;
+}
+
+static inline int kputsn_(const void *p, int l, kstring_t *s)
+{
+ if (s->l + l > s->m) {
+ char *tmp;
+ s->m = s->l + l;
+ kroundup32(s->m);
+ if ((tmp = (char*)realloc(s->s, s->m)))
+ s->s = tmp;
+ else
+ return EOF;
+ }
+ memcpy(s->s + s->l, p, l);
+ s->l += l;
+ return l;
+}
+
+static inline int kputw(int c, kstring_t *s)
+{
+ char buf[16];
+ int i, l = 0;
+ unsigned int x = c;
+ if (c < 0) x = -x;
+ do { buf[l++] = x%10 + '0'; x /= 10; } while (x > 0);
+ if (c < 0) buf[l++] = '-';
+ if (s->l + l + 1 >= s->m) {
+ char *tmp;
+ s->m = s->l + l + 2;
+ kroundup32(s->m);
+ if ((tmp = (char*)realloc(s->s, s->m)))
+ s->s = tmp;
+ else
+ return EOF;
+ }
+ for (i = l - 1; i >= 0; --i) s->s[s->l++] = buf[i];
+ s->s[s->l] = 0;
+ return 0;
+}
+
+static inline int kputuw(unsigned c, kstring_t *s)
+{
+ char buf[16];
+ int l, i;
+ unsigned x;
+ if (c == 0) return kputc('0', s);
+ for (l = 0, x = c; x > 0; x /= 10) buf[l++] = x%10 + '0';
+ if (s->l + l + 1 >= s->m) {
+ char *tmp;
+ s->m = s->l + l + 2;
+ kroundup32(s->m);
+ if ((tmp = (char*)realloc(s->s, s->m)))
+ s->s = tmp;
+ else
+ return EOF;
+ }
+ for (i = l - 1; i >= 0; --i) s->s[s->l++] = buf[i];
+ s->s[s->l] = 0;
+ return 0;
+}
+
+static inline int kputl(long c, kstring_t *s)
+{
+ char buf[32];
+ int i, l = 0;
+ unsigned long x = c;
+ if (c < 0) x = -x;
+ do { buf[l++] = x%10 + '0'; x /= 10; } while (x > 0);
+ if (c < 0) buf[l++] = '-';
+ if (s->l + l + 1 >= s->m) {
+ char *tmp;
+ s->m = s->l + l + 2;
+ kroundup32(s->m);
+ if ((tmp = (char*)realloc(s->s, s->m)))
+ s->s = tmp;
+ else
+ return EOF;
+ }
+ for (i = l - 1; i >= 0; --i) s->s[s->l++] = buf[i];
+ s->s[s->l] = 0;
+ return 0;
+}
+
+/*
+ * Returns 's' split by delimiter, with *n being the number of components;
+ * NULL on failue.
+ */
+static inline int *ksplit(kstring_t *s, int delimiter, int *n)
+{
+ int max = 0, *offsets = 0;
+ *n = ksplit_core(s->s, delimiter, &max, &offsets);
+ return offsets;
+}
+
+#endif
--- /dev/null
+/*
+ Copyright (C) 2014 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining a copy
+ of this software and associated documentation files (the "Software"), to deal
+ in the Software without restriction, including without limitation the rights
+ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+ copies of the Software, and to permit persons to whom the Software is
+ furnished to do so, subject to the following conditions:
+
+ The above copyright notice and this permission notice shall be included in
+ all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+ IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+ FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+ AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+ LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+ OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
+ THE SOFTWARE.
+*/
+
+/*
+ Regions indexing with an optional payload. Inspired by samtools/bedidx.c.
+ This code is intended as future replacement of bcf_sr_regions_t.
+
+ Example of usage:
+
+ // Init the parser and print regions. In this example the payload is a
+ // pointer to a string. For the description of parse_custom and
+ // free_custom functions, see regidx_parse_f and regidx_free_f below,
+ // and for working example see test/test-regidx.c.
+ regidx_t *idx = regidx_init(in_fname,parse_custom,free_custom,sizeof(char*),NULL);
+
+ // Query overlap with chr:from-to
+ regitr_t itr;
+ if ( regidx_overlap(idx, chr,from,to, &itr) ) printf("There is an overlap!\n");
+
+ while ( REGITR_OVERLAP(itr,from,to) )
+ {
+ printf("[%d,%d] overlaps with [%d,%d], payload=%s\n", from,to,
+ REGITR_START(itr), REGITR_END(itr), REGITR_PAYLOAD(itr,char*));
+ itr.i++;
+ }
+
+ regidx_destroy(regs);
+*/
+
+#ifndef HTSLIB_REGIDX_H
+#define HTSLIB_REGIDX_H
+
+#include <stdio.h>
+#include <inttypes.h>
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+typedef struct _regidx_t regidx_t;
+typedef struct
+{
+ uint32_t start, end;
+}
+reg_t;
+typedef struct
+{
+ int i, n;
+ reg_t *reg;
+ void *payload;
+}
+regitr_t;
+
+#define REGITR_START(itr) (itr).reg[(itr).i].start
+#define REGITR_END(itr) (itr).reg[(itr).i].end
+#define REGITR_PAYLOAD(itr,type_t) ((type_t*)(itr).payload)[(itr).i]
+#define REGITR_OVERLAP(itr,from,to) (itr.i < itr.n && REGITR_START(itr)<=to && REGITR_END(itr)>=from )
+
+/*
+ * regidx_parse_f - Function to parse one input line, such as regidx_parse_bed
+ * or regidx_parse_tab below. The function is expected to set `chr_from` and
+ * `chr_to` to point to first and last character of chromosome name and set
+ * coordinates `reg->start` and `reg->end` (0-based, inclusive). If
+ * regidx_init() was called with non-zero payload_size, the `payload` points
+ * to a memory location of the payload_size and `usr` is data passed to
+ * regidx_init(). Any memory allocated by the function will be freed by
+ * regidx_free_f on regidx_destroy().
+ *
+ * Return value: 0 on success, -1 to skip a record, -2 on fatal error.
+ */
+typedef int (*regidx_parse_f)(const char *line, char **chr_beg, char **chr_end, reg_t *reg, void *payload, void *usr);
+typedef void (*regidx_free_f)(void *payload);
+
+int regidx_parse_bed(const char*,char**,char**,reg_t*,void*,void*); // CHROM,FROM,TO (0-based,right-open)
+int regidx_parse_tab(const char*,char**,char**,reg_t*,void*,void*); // CHROM,POS (1-based, inclusive)
+
+/*
+ * regidx_init() - creates new index
+ * @param fname: input file name or NULL if regions will be added one-by-one via regidx_insert()
+ * @param parsef: regidx_parse_bed, regidx_parse_tab or see description of regidx_parse_f. If NULL,
+ * the format will be autodected, currently either regidx_parse_tab (the default) or
+ * regidx_parse_bed (file must be named 'bed' or 'bed.gz') will be used. Note that
+ * the exact autodetection algorithm will change.
+ * @param freef: NULL or see description of regidx_parse_f
+ * @param payload_size: 0 with regidx_parse_bed, regidx_parse_tab or see regidx_parse_f
+ * @param usr: optional user data passed to regidx_parse_f
+ *
+ * Returns index on success or NULL on error.
+ */
+regidx_t *regidx_init(const char *fname, regidx_parse_f parsef, regidx_free_f freef, size_t payload_size, void *usr);
+
+/*
+ * regidx_destroy() - free memory allocated by regidx_init
+ */
+void regidx_destroy(regidx_t *idx);
+
+/*
+ * regidx_overlap() - check overlap of the location chr:from-to with regions
+ * @param start,end: 0-based start, end coordinate (inclusive)
+ * @param itr: pointer to iterator, can be NULL if not needed
+ *
+ * Returns 0 if there is no overlap or 1 if overlap is found. The overlapping
+ * regions can be iterated as shown in the example above.
+ */
+int regidx_overlap(regidx_t *idx, const char *chr, uint32_t start, uint32_t end, regitr_t *itr);
+
+/*
+ * regidx_insert() - add a new region.
+ *
+ * After last region has been added, call regidx_insert(idx,NULL) to
+ * build the index.
+ *
+ * Returns 0 on success or -1 on error.
+ */
+int regidx_insert(regidx_t *idx, char *line);
+
+/*
+ * regidx_seq_names() - return list of all sequence names
+ */
+char **regidx_seq_names(regidx_t *idx, int *n);
+
+/*
+ * regidx_seq_nregs() - number of regions
+ * regidx_nregs() - total number of regions
+ */
+int regidx_seq_nregs(regidx_t *idx, const char *seq);
+int regidx_nregs(regidx_t *idx);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* sam.h -- SAM and BAM file I/O and manipulation.
+
+ Copyright (C) 2008, 2009, 2013-2014 Genome Research Ltd.
+ Copyright (C) 2010, 2012, 2013 Broad Institute.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_SAM_H
+#define HTSLIB_SAM_H
+
+#include <stdint.h>
+#include "hts.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/**********************
+ *** SAM/BAM header ***
+ **********************/
+
+/*! @typedef
+ @abstract Structure for the alignment header.
+ @field n_targets number of reference sequences
+ @field l_text length of the plain text in the header
+ @field target_len lengths of the reference sequences
+ @field target_name names of the reference sequences
+ @field text plain text
+ @field sdict header dictionary
+ */
+
+typedef struct {
+ int32_t n_targets, ignore_sam_err;
+ uint32_t l_text;
+ uint32_t *target_len;
+ int8_t *cigar_tab;
+ char **target_name;
+ char *text;
+ void *sdict;
+} bam_hdr_t;
+
+/****************************
+ *** CIGAR related macros ***
+ ****************************/
+
+#define BAM_CMATCH 0
+#define BAM_CINS 1
+#define BAM_CDEL 2
+#define BAM_CREF_SKIP 3
+#define BAM_CSOFT_CLIP 4
+#define BAM_CHARD_CLIP 5
+#define BAM_CPAD 6
+#define BAM_CEQUAL 7
+#define BAM_CDIFF 8
+#define BAM_CBACK 9
+
+#define BAM_CIGAR_STR "MIDNSHP=XB"
+#define BAM_CIGAR_SHIFT 4
+#define BAM_CIGAR_MASK 0xf
+#define BAM_CIGAR_TYPE 0x3C1A7
+
+#define bam_cigar_op(c) ((c)&BAM_CIGAR_MASK)
+#define bam_cigar_oplen(c) ((c)>>BAM_CIGAR_SHIFT)
+#define bam_cigar_opchr(c) (BAM_CIGAR_STR[bam_cigar_op(c)])
+#define bam_cigar_gen(l, o) ((l)<<BAM_CIGAR_SHIFT|(o))
+
+/* bam_cigar_type returns a bit flag with:
+ * bit 1 set if the cigar operation consumes the query
+ * bit 2 set if the cigar operation consumes the reference
+ *
+ * For reference, the unobfuscated truth table for this function is:
+ * BAM_CIGAR_TYPE QUERY REFERENCE
+ * --------------------------------
+ * BAM_CMATCH 1 1
+ * BAM_CINS 1 0
+ * BAM_CDEL 0 1
+ * BAM_CREF_SKIP 0 1
+ * BAM_CSOFT_CLIP 1 0
+ * BAM_CHARD_CLIP 0 0
+ * BAM_CPAD 0 0
+ * BAM_CEQUAL 1 1
+ * BAM_CDIFF 1 1
+ * BAM_CBACK 0 0
+ * --------------------------------
+ */
+#define bam_cigar_type(o) (BAM_CIGAR_TYPE>>((o)<<1)&3) // bit 1: consume query; bit 2: consume reference
+
+/*! @abstract the read is paired in sequencing, no matter whether it is mapped in a pair */
+#define BAM_FPAIRED 1
+/*! @abstract the read is mapped in a proper pair */
+#define BAM_FPROPER_PAIR 2
+/*! @abstract the read itself is unmapped; conflictive with BAM_FPROPER_PAIR */
+#define BAM_FUNMAP 4
+/*! @abstract the mate is unmapped */
+#define BAM_FMUNMAP 8
+/*! @abstract the read is mapped to the reverse strand */
+#define BAM_FREVERSE 16
+/*! @abstract the mate is mapped to the reverse strand */
+#define BAM_FMREVERSE 32
+/*! @abstract this is read1 */
+#define BAM_FREAD1 64
+/*! @abstract this is read2 */
+#define BAM_FREAD2 128
+/*! @abstract not primary alignment */
+#define BAM_FSECONDARY 256
+/*! @abstract QC failure */
+#define BAM_FQCFAIL 512
+/*! @abstract optical or PCR duplicate */
+#define BAM_FDUP 1024
+/*! @abstract supplementary alignment */
+#define BAM_FSUPPLEMENTARY 2048
+
+/*************************
+ *** Alignment records ***
+ *************************/
+
+/*! @typedef
+ @abstract Structure for core alignment information.
+ @field tid chromosome ID, defined by bam_hdr_t
+ @field pos 0-based leftmost coordinate
+ @field bin bin calculated by bam_reg2bin()
+ @field qual mapping quality
+ @field l_qname length of the query name
+ @field flag bitwise flag
+ @field n_cigar number of CIGAR operations
+ @field l_qseq length of the query sequence (read)
+ @field mtid chromosome ID of next read in template, defined by bam_hdr_t
+ @field mpos 0-based leftmost coordinate of next read in template
+ */
+typedef struct {
+ int32_t tid;
+ int32_t pos;
+ uint32_t bin:16, qual:8, l_qname:8;
+ uint32_t flag:16, n_cigar:16;
+ int32_t l_qseq;
+ int32_t mtid;
+ int32_t mpos;
+ int32_t isize;
+} bam1_core_t;
+
+/*! @typedef
+ @abstract Structure for one alignment.
+ @field core core information about the alignment
+ @field l_data current length of bam1_t::data
+ @field m_data maximum length of bam1_t::data
+ @field data all variable-length data, concatenated; structure: qname-cigar-seq-qual-aux
+
+ @discussion Notes:
+
+ 1. qname is zero tailing and core.l_qname includes the tailing '\0'.
+ 2. l_qseq is calculated from the total length of an alignment block
+ on reading or from CIGAR.
+ 3. cigar data is encoded 4 bytes per CIGAR operation.
+ 4. seq is nybble-encoded according to bam_nt16_table.
+ */
+typedef struct {
+ bam1_core_t core;
+ int l_data, m_data;
+ uint8_t *data;
+#ifndef BAM_NO_ID
+ uint64_t id;
+#endif
+} bam1_t;
+
+/*! @function
+ @abstract Get whether the query is on the reverse strand
+ @param b pointer to an alignment
+ @return boolean true if query is on the reverse strand
+ */
+#define bam_is_rev(b) (((b)->core.flag&BAM_FREVERSE) != 0)
+/*! @function
+ @abstract Get whether the query's mate is on the reverse strand
+ @param b pointer to an alignment
+ @return boolean true if query's mate on the reverse strand
+ */
+#define bam_is_mrev(b) (((b)->core.flag&BAM_FMREVERSE) != 0)
+/*! @function
+ @abstract Get the name of the query
+ @param b pointer to an alignment
+ @return pointer to the name string, null terminated
+ */
+#define bam_get_qname(b) ((char*)(b)->data)
+/*! @function
+ @abstract Get the CIGAR array
+ @param b pointer to an alignment
+ @return pointer to the CIGAR array
+
+ @discussion In the CIGAR array, each element is a 32-bit integer. The
+ lower 4 bits gives a CIGAR operation and the higher 28 bits keep the
+ length of a CIGAR.
+ */
+#define bam_get_cigar(b) ((uint32_t*)((b)->data + (b)->core.l_qname))
+/*! @function
+ @abstract Get query sequence
+ @param b pointer to an alignment
+ @return pointer to sequence
+
+ @discussion Each base is encoded in 4 bits: 1 for A, 2 for C, 4 for G,
+ 8 for T and 15 for N. Two bases are packed in one byte with the base
+ at the higher 4 bits having smaller coordinate on the read. It is
+ recommended to use bam_seqi() macro to get the base.
+ */
+#define bam_get_seq(b) ((b)->data + ((b)->core.n_cigar<<2) + (b)->core.l_qname)
+/*! @function
+ @abstract Get query quality
+ @param b pointer to an alignment
+ @return pointer to quality string
+ */
+#define bam_get_qual(b) ((b)->data + ((b)->core.n_cigar<<2) + (b)->core.l_qname + (((b)->core.l_qseq + 1)>>1))
+/*! @function
+ @abstract Get auxiliary data
+ @param b pointer to an alignment
+ @return pointer to the concatenated auxiliary data
+ */
+#define bam_get_aux(b) ((b)->data + ((b)->core.n_cigar<<2) + (b)->core.l_qname + (((b)->core.l_qseq + 1)>>1) + (b)->core.l_qseq)
+/*! @function
+ @abstract Get length of auxiliary data
+ @param b pointer to an alignment
+ @return length of the concatenated auxiliary data
+ */
+#define bam_get_l_aux(b) ((b)->l_data - ((b)->core.n_cigar<<2) - (b)->core.l_qname - (b)->core.l_qseq - (((b)->core.l_qseq + 1)>>1))
+/*! @function
+ @abstract Get a base on read
+ @param s Query sequence returned by bam_get_seq()
+ @param i The i-th position, 0-based
+ @return 4-bit integer representing the base.
+ */
+#define bam_seqi(s, i) ((s)[(i)>>1] >> ((~(i)&1)<<2) & 0xf)
+
+/**************************
+ *** Exported functions ***
+ **************************/
+
+ /***************
+ *** BAM I/O ***
+ ***************/
+
+ bam_hdr_t *bam_hdr_init(void);
+ bam_hdr_t *bam_hdr_read(BGZF *fp);
+ int bam_hdr_write(BGZF *fp, const bam_hdr_t *h) HTS_RESULT_USED;
+ void bam_hdr_destroy(bam_hdr_t *h);
+ int bam_name2id(bam_hdr_t *h, const char *ref);
+ bam_hdr_t* bam_hdr_dup(const bam_hdr_t *h0);
+
+ bam1_t *bam_init1(void);
+ void bam_destroy1(bam1_t *b);
+ int bam_read1(BGZF *fp, bam1_t *b) HTS_RESULT_USED;
+ int bam_write1(BGZF *fp, const bam1_t *b) HTS_RESULT_USED;
+ bam1_t *bam_copy1(bam1_t *bdst, const bam1_t *bsrc);
+ bam1_t *bam_dup1(const bam1_t *bsrc);
+
+ int bam_cigar2qlen(int n_cigar, const uint32_t *cigar);
+ int bam_cigar2rlen(int n_cigar, const uint32_t *cigar);
+
+ /*!
+ @abstract Calculate the rightmost base position of an alignment on the
+ reference genome.
+
+ @param b pointer to an alignment
+ @return the coordinate of the first base after the alignment, 0-based
+
+ @discussion For a mapped read, this is just b->core.pos + bam_cigar2rlen.
+ For an unmapped read (either according to its flags or if it has no cigar
+ string), we return b->core.pos + 1 by convention.
+ */
+ int32_t bam_endpos(const bam1_t *b);
+
+ int bam_str2flag(const char *str); /** returns negative value on error */
+ char *bam_flag2str(int flag); /** The string must be freed by the user */
+
+ /*************************
+ *** BAM/CRAM indexing ***
+ *************************/
+
+ // These BAM iterator functions work only on BAM files. To work with either
+ // BAM or CRAM files use the sam_index_load() & sam_itr_*() functions.
+ #define bam_itr_destroy(iter) hts_itr_destroy(iter)
+ #define bam_itr_queryi(idx, tid, beg, end) sam_itr_queryi(idx, tid, beg, end)
+ #define bam_itr_querys(idx, hdr, region) sam_itr_querys(idx, hdr, region)
+ #define bam_itr_next(htsfp, itr, r) hts_itr_next((htsfp)->fp.bgzf, (itr), (r), 0)
+
+// Load/build .csi or .bai BAM index file. Does not work with CRAM.
+// It is recommended to use the sam_index_* functions below instead.
+#define bam_index_load(fn) hts_idx_load((fn), HTS_FMT_BAI)
+#define bam_index_build(fn, min_shift) (sam_index_build((fn), (min_shift)))
+
+/// Load a BAM (.csi or .bai) or CRAM (.crai) index file
+/** @param fp File handle of the data file whose index is being opened
+ @param fn BAM/CRAM/etc filename to search alongside for the index file
+ @return The index, or NULL if an error occurred.
+*/
+hts_idx_t *sam_index_load(htsFile *fp, const char *fn);
+
+/// Load a specific BAM (.csi or .bai) or CRAM (.crai) index file
+/** @param fp File handle of the data file whose index is being opened
+ @param fn BAM/CRAM/etc data file filename
+ @param fnidx Index filename, or NULL to search alongside @a fn
+ @return The index, or NULL if an error occurred.
+*/
+hts_idx_t *sam_index_load2(htsFile *fp, const char *fn, const char *fnidx);
+
+/// Generate and save an index file
+/** @param fn Input BAM/etc filename, to which .csi/etc will be added
+ @param min_shift Positive to generate CSI, or 0 to generate BAI
+ @return 0 if successful, or negative if an error occurred (usually -1; or
+ -2: opening fn failed; -3: format not indexable)
+*/
+int sam_index_build(const char *fn, int min_shift) HTS_RESULT_USED;
+
+/// Generate and save an index to a specific file
+/** @param fn Input BAM/CRAM/etc filename
+ @param fnidx Output filename, or NULL to add .bai/.csi/etc to @a fn
+ @param min_shift Positive to generate CSI, or 0 to generate BAI
+ @return 0 if successful, or negative if an error occurred.
+*/
+int sam_index_build2(const char *fn, const char *fnidx, int min_shift) HTS_RESULT_USED;
+
+ #define sam_itr_destroy(iter) hts_itr_destroy(iter)
+ hts_itr_t *sam_itr_queryi(const hts_idx_t *idx, int tid, int beg, int end);
+ hts_itr_t *sam_itr_querys(const hts_idx_t *idx, bam_hdr_t *hdr, const char *region);
+ #define sam_itr_next(htsfp, itr, r) hts_itr_next((htsfp)->fp.bgzf, (itr), (r), (htsfp))
+
+ /***************
+ *** SAM I/O ***
+ ***************/
+
+ #define sam_open(fn, mode) (hts_open((fn), (mode)))
+ #define sam_open_format(fn, mode, fmt) (hts_open_format((fn), (mode), (fmt)))
+ #define sam_close(fp) hts_close(fp)
+
+ int sam_open_mode(char *mode, const char *fn, const char *format);
+
+ // A version of sam_open_mode that can handle ,key=value options.
+ // The format string is allocated and returned, to be freed by the caller.
+ // Prefix should be "r" or "w",
+ char *sam_open_mode_opts(const char *fn,
+ const char *mode,
+ const char *format);
+
+ typedef htsFile samFile;
+ bam_hdr_t *sam_hdr_parse(int l_text, const char *text);
+ bam_hdr_t *sam_hdr_read(samFile *fp);
+ int sam_hdr_write(samFile *fp, const bam_hdr_t *h) HTS_RESULT_USED;
+
+ int sam_parse1(kstring_t *s, bam_hdr_t *h, bam1_t *b) HTS_RESULT_USED;
+ int sam_format1(const bam_hdr_t *h, const bam1_t *b, kstring_t *str) HTS_RESULT_USED;
+ int sam_read1(samFile *fp, bam_hdr_t *h, bam1_t *b) HTS_RESULT_USED;
+ int sam_write1(samFile *fp, const bam_hdr_t *h, const bam1_t *b) HTS_RESULT_USED;
+
+ /*************************************
+ *** Manipulating auxiliary fields ***
+ *************************************/
+
+ uint8_t *bam_aux_get(const bam1_t *b, const char tag[2]);
+ int32_t bam_aux2i(const uint8_t *s);
+ double bam_aux2f(const uint8_t *s);
+ char bam_aux2A(const uint8_t *s);
+ char *bam_aux2Z(const uint8_t *s);
+
+ void bam_aux_append(bam1_t *b, const char tag[2], char type, int len, uint8_t *data);
+ int bam_aux_del(bam1_t *b, uint8_t *s);
+
+/**************************
+ *** Pileup and Mpileup ***
+ **************************/
+
+#if !defined(BAM_NO_PILEUP)
+
+/*! @typedef
+ @abstract Structure for one alignment covering the pileup position.
+ @field b pointer to the alignment
+ @field qpos position of the read base at the pileup site, 0-based
+ @field indel indel length; 0 for no indel, positive for ins and negative for del
+ @field level the level of the read in the "viewer" mode
+ @field is_del 1 iff the base on the padded read is a deletion
+ @field is_head ???
+ @field is_tail ???
+ @field is_refskip ???
+ @field aux ???
+
+ @discussion See also bam_plbuf_push() and bam_lplbuf_push(). The
+ difference between the two functions is that the former does not
+ set bam_pileup1_t::level, while the later does. Level helps the
+ implementation of alignment viewers, but calculating this has some
+ overhead.
+ */
+typedef struct {
+ bam1_t *b;
+ int32_t qpos;
+ int indel, level;
+ uint32_t is_del:1, is_head:1, is_tail:1, is_refskip:1, aux:28;
+} bam_pileup1_t;
+
+typedef int (*bam_plp_auto_f)(void *data, bam1_t *b);
+
+struct __bam_plp_t;
+typedef struct __bam_plp_t *bam_plp_t;
+
+struct __bam_mplp_t;
+typedef struct __bam_mplp_t *bam_mplp_t;
+
+ /**
+ * bam_plp_init() - sets an iterator over multiple
+ * @func: see mplp_func in bam_plcmd.c in samtools for an example. Expected return
+ * status: 0 on success, -1 on end, < -1 on non-recoverable errors
+ * @data: user data to pass to @func
+ */
+ bam_plp_t bam_plp_init(bam_plp_auto_f func, void *data);
+ void bam_plp_destroy(bam_plp_t iter);
+ int bam_plp_push(bam_plp_t iter, const bam1_t *b);
+ const bam_pileup1_t *bam_plp_next(bam_plp_t iter, int *_tid, int *_pos, int *_n_plp);
+ const bam_pileup1_t *bam_plp_auto(bam_plp_t iter, int *_tid, int *_pos, int *_n_plp);
+ void bam_plp_set_maxcnt(bam_plp_t iter, int maxcnt);
+ void bam_plp_reset(bam_plp_t iter);
+
+ bam_mplp_t bam_mplp_init(int n, bam_plp_auto_f func, void **data);
+ /**
+ * bam_mplp_init_overlaps() - if called, mpileup will detect overlapping
+ * read pairs and for each base pair set the base quality of the
+ * lower-quality base to zero, thus effectively discarding it from
+ * calling. If the two bases are identical, the quality of the other base
+ * is increased to the sum of their qualities (capped at 200), otherwise
+ * it is multiplied by 0.8.
+ */
+ void bam_mplp_init_overlaps(bam_mplp_t iter);
+ void bam_mplp_destroy(bam_mplp_t iter);
+ void bam_mplp_set_maxcnt(bam_mplp_t iter, int maxcnt);
+ int bam_mplp_auto(bam_mplp_t iter, int *_tid, int *_pos, int *n_plp, const bam_pileup1_t **plp);
+
+#endif // ~!defined(BAM_NO_PILEUP)
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* synced_bcf_reader.h -- stream through multiple VCF files.
+
+ Copyright (C) 2012-2014 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+/*
+ The synced_bcf_reader allows to keep multiple VCFs open and stream them
+ using the next_line iterator in a seamless matter without worrying about
+ chromosomes and synchronizing the sites. This is used by vcfcheck to
+ compare multiple VCFs simultaneously and is used also for merging,
+ creating intersections, etc.
+
+ The synced_bcf_reader also provides API for reading indexed BCF/VCF,
+ hiding differences in BCF/VCF opening, indexing and reading.
+
+
+ Example of usage:
+
+ bcf_srs_t *sr = bcf_sr_init();
+ for (i=0; i<nfiles; i++)
+ bcf_sr_add_reader(sr,files[i]);
+ while ( bcf_sr_next_line(sr) )
+ {
+ for (i=0; i<nfiles; i++)
+ {
+ bcf1_t *line = bcf_sr_get_line(sr,i);
+ ...
+ }
+ }
+ bcf_sr_destroy(sr);
+*/
+
+#ifndef HTSLIB_SYNCED_BCF_READER_H
+#define HTSLIB_SYNCED_BCF_READER_H
+
+#include "hts.h"
+#include "vcf.h"
+#include "tbx.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+// How should be treated sites with the same position but different alleles
+#define COLLAPSE_NONE 0 // require the exact same set of alleles in all files
+#define COLLAPSE_SNPS 1 // allow different alleles, as long as they all are SNPs
+#define COLLAPSE_INDELS 2 // the same as above, but with indels
+#define COLLAPSE_ANY 4 // any combination of alleles can be returned by bcf_sr_next_line()
+#define COLLAPSE_SOME 8 // at least some of the ALTs must match
+#define COLLAPSE_BOTH (COLLAPSE_SNPS|COLLAPSE_INDELS)
+
+typedef struct _bcf_sr_regions_t
+{
+ // for reading from tabix-indexed file (big data)
+ tbx_t *tbx; // tabix index
+ hts_itr_t *itr; // tabix iterator
+ kstring_t line; // holder of the current line, set only when reading from tabix-indexed files
+ htsFile *file;
+ char *fname;
+ int is_bin; // is open in binary mode (tabix access)
+ char **als; // parsed alleles if targets_als set and _regions_match_alleles called
+ kstring_t als_str; // block of parsed alleles
+ int nals, mals; // number of set alleles and the size of allocated array
+ int als_type; // alleles type, currently VCF_SNP or VCF_INDEL
+
+ // user handler to deal with skipped regions without a counterpart in VCFs
+ void (*missed_reg_handler)(struct _bcf_sr_regions_t *, void *);
+ void *missed_reg_data;
+
+ // for in-memory regions (small data)
+ struct _region_t *regs; // the regions
+
+ // shared by both tabix-index and in-memory regions
+ void *seq_hash; // keys: sequence names, values: index to seqs
+ char **seq_names; // sequence names
+ int nseqs; // number of sequences (chromosomes) in the file
+ int iseq; // current position: chr name, index to snames
+ int start, end; // current position: start, end of the region (0-based)
+ int prev_seq, prev_start;
+}
+bcf_sr_regions_t;
+
+typedef struct
+{
+ htsFile *file;
+ tbx_t *tbx_idx;
+ hts_idx_t *bcf_idx;
+ bcf_hdr_t *header;
+ hts_itr_t *itr;
+ char *fname;
+ bcf1_t **buffer; // cached VCF records. First is the current record synced across the reader
+ int nbuffer, mbuffer; // number of cached records (including the current record); number of allocated records
+ int nfilter_ids, *filter_ids; // -1 for ".", otherwise filter id as returned by bcf_hdr_id2int
+ int *samples, n_smpl; // list of columns in the order consistent with bcf_srs_t.samples
+}
+bcf_sr_t;
+
+typedef enum
+{
+ open_failed, not_bgzf, idx_load_failed, file_type_error, api_usage_error,
+ header_error, no_eof
+}
+bcf_sr_error;
+
+typedef struct
+{
+ // Parameters controlling the logic
+ int collapse; // How should the duplicate sites be treated. One of the COLLAPSE_* types above.
+ char *apply_filters; // If set, sites where none of the FILTER strings is listed
+ // will be skipped. Active only at the time of
+ // initialization, that is during the add_reader()
+ // calls. Therefore, each reader can be initialized with different
+ // filters.
+ int require_index; // Some tools do not need random access
+ int max_unpack; // When reading VCFs and knowing some fields will not be needed, boost performance of vcf_parse1
+ int *has_line; // Corresponds to return value of bcf_sr_next_line but is not limited by sizeof(int). Use bcf_sr_has_line macro to query.
+ bcf_sr_error errnum;
+
+ // Auxiliary data
+ bcf_sr_t *readers;
+ int nreaders;
+ int streaming; // reading mode: index-jumping or streaming
+ int explicit_regs; // was the list of regions se by bcf_sr_set_regions or guessed from tabix index?
+ char **samples; // List of samples
+ bcf_sr_regions_t *regions, *targets; // see bcf_sr_set_[targets|regions] for description
+ int targets_als; // subset to targets not only by position but also by alleles?
+ int targets_exclude;
+ kstring_t tmps;
+ int n_smpl;
+}
+bcf_srs_t;
+
+/** Init bcf_srs_t struct */
+bcf_srs_t *bcf_sr_init(void);
+
+/** Destroy bcf_srs_t struct */
+void bcf_sr_destroy(bcf_srs_t *readers);
+
+char *bcf_sr_strerror(int errnum);
+
+
+/**
+ * bcf_sr_add_reader() - open new reader
+ * @readers: holder of the open readers
+ * @fname: the VCF file
+ *
+ * Returns 1 if the call succeeded, or 0 on error.
+ *
+ * See also the bcf_srs_t data structure for parameters controlling
+ * the reader's logic.
+ */
+int bcf_sr_add_reader(bcf_srs_t *readers, const char *fname);
+void bcf_sr_remove_reader(bcf_srs_t *files, int i);
+
+/**
+ * bcf_sr_next_line() - the iterator
+ * @readers: holder of the open readers
+ *
+ * Returns the number of readers which have the current line
+ * (bcf_sr_t.buffer[0]) set at this position. Use the bcf_sr_has_line macro to
+ * determine which of the readers are set.
+ */
+int bcf_sr_next_line(bcf_srs_t *readers);
+#define bcf_sr_has_line(readers, i) (readers)->has_line[i]
+#define bcf_sr_get_line(_readers, i) ((_readers)->has_line[i] ? ((_readers)->readers[i].buffer[0]) : NULL)
+#define bcf_sr_swap_line(_readers, i, lieu) { bcf1_t *tmp = lieu; lieu = (_readers)->readers[i].buffer[0]; (_readers)->readers[i].buffer[0] = tmp; }
+#define bcf_sr_region_done(_readers,i) (!(_readers)->has_line[i] && !(_readers)->readers[i].nbuffer ? 1 : 0)
+#define bcf_sr_get_header(_readers, i) (_readers)->readers[i].header
+#define bcf_sr_get_reader(_readers, i) &((_readers)->readers[i])
+
+/**
+ * bcf_sr_seek() - set all readers to selected position
+ * @seq: sequence name; NULL to seek to start
+ * @pos: 0-based coordinate
+ */
+int bcf_sr_seek(bcf_srs_t *readers, const char *seq, int pos);
+
+/**
+ * bcf_sr_set_samples() - sets active samples
+ * @readers: holder of the open readers
+ * @samples: this can be one of: file name with one sample per line;
+ * or column-separated list of samples; or '-' for a list of
+ * samples shared by all files. If first character is the
+ * exclamation mark, all but the listed samples are included.
+ * @is_file: 0: list of samples; 1: file with sample names
+ *
+ * Returns 1 if the call succeeded, or 0 on error.
+ */
+int bcf_sr_set_samples(bcf_srs_t *readers, const char *samples, int is_file);
+
+/**
+ * bcf_sr_set_targets(), bcf_sr_set_regions() - init targets/regions
+ * @readers: holder of the open readers
+ * @targets: list of regions, one-based and inclusive.
+ * @is_fname: 0: targets is a comma-separated list of regions (chr,chr:from-to)
+ * 1: targets is a tabix indexed file with a list of regions
+ * (<chr,pos> or <chr,from,to>)
+ *
+ * Returns 0 if the call succeeded, or -1 on error.
+ *
+ * Both functions behave the same way, unlisted positions will be skipped by
+ * bcf_sr_next_line(). However, there is an important difference: regions use
+ * index to jump to desired positions while targets streams the whole files
+ * and merely skip unlisted positions.
+ *
+ * Moreover, bcf_sr_set_targets() accepts an optional parameter $alleles which
+ * is intepreted as a 1-based column index in the tab-delimited file where
+ * alleles are listed. This in principle enables to perform the COLLAPSE_*
+ * logic also with tab-delimited files. However, the current implementation
+ * considers the alleles merely as a suggestion for prioritizing one of possibly
+ * duplicate VCF lines. It is up to the caller to examine targets->als if
+ * perfect match is sought after. Note that the duplicate positions in targets
+ * file are currently not supported.
+ * Targets (but not regions) can be prefixed with "^" to request logical complement,
+ * for example "^X,Y,MT" indicates that sequences X, Y and MT should be skipped.
+ */
+int bcf_sr_set_targets(bcf_srs_t *readers, const char *targets, int is_file, int alleles);
+int bcf_sr_set_regions(bcf_srs_t *readers, const char *regions, int is_file);
+
+
+
+/*
+ * bcf_sr_regions_init()
+ * @regions: regions can be either a comma-separated list of regions
+ * (chr|chr:pos|chr:from-to|chr:from-) or VCF, BED, or
+ * tab-delimited file (the default). Uncompressed files
+ * are stored in memory while bgzip-compressed and tabix-indexed
+ * region files are streamed.
+ * @is_file: 0: regions is a comma-separated list of regions
+ * (chr|chr:pos|chr:from-to|chr:from-)
+ * 1: VCF, BED or tab-delimited file
+ * @chr, from, to:
+ * Column indexes of chromosome, start position and end position
+ * in the tab-delimited file. The positions are 1-based and
+ * inclusive.
+ * These parameters are ignored when reading from VCF, BED or
+ * tabix-indexed files. When end position column is not present,
+ * supply 'from' in place of 'to'. When 'to' is negative, first
+ * abs(to) will be attempted and if that fails, 'from' will be used
+ * instead.
+ */
+bcf_sr_regions_t *bcf_sr_regions_init(const char *regions, int is_file, int chr, int from, int to);
+void bcf_sr_regions_destroy(bcf_sr_regions_t *regions);
+
+/*
+ * bcf_sr_regions_seek() - seek to the chromosome block
+ *
+ * Returns 0 on success or -1 on failure. Sets reg->seq appropriately and
+ * reg->start,reg->end to -1.
+ */
+int bcf_sr_regions_seek(bcf_sr_regions_t *regions, const char *chr);
+
+/*
+ * bcf_sr_regions_next() - retrieves next region. Returns 0 on success and -1
+ * when all regions have been read. The fields reg->seq, reg->start and
+ * reg->end are filled with the genomic coordinates on succes or with
+ * NULL,-1,-1 when no region is available. The coordinates are 0-based,
+ * inclusive.
+ */
+int bcf_sr_regions_next(bcf_sr_regions_t *reg);
+
+/*
+ * bcf_sr_regions_overlap() - checks if the interval <start,end> overlaps any of
+ * the regions, the coordinates are 0-based, inclusive. The coordinate queries
+ * must come in ascending order.
+ *
+ * Returns 0 if the position is in regions; -1 if the position is not in the
+ * regions and more regions exist; -2 if not in the regions and there are no more
+ * regions left.
+ */
+int bcf_sr_regions_overlap(bcf_sr_regions_t *reg, const char *seq, int start, int end);
+
+/*
+ * bcf_sr_regions_flush() - calls repeatedly regs->missed_reg_handler() until
+ * all remaining records are processed.
+ */
+void bcf_sr_regions_flush(bcf_sr_regions_t *regs);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* tbx.h -- tabix API functions.
+
+ Copyright (C) 2009, 2012-2015 Genome Research Ltd.
+ Copyright (C) 2010, 2012 Broad Institute.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_TBX_H
+#define HTSLIB_TBX_H
+
+#include "hts.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+#define TBX_MAX_SHIFT 31
+
+#define TBX_GENERIC 0
+#define TBX_SAM 1
+#define TBX_VCF 2
+#define TBX_UCSC 0x10000
+
+typedef struct {
+ int32_t preset;
+ int32_t sc, bc, ec; // seq col., beg col. and end col.
+ int32_t meta_char, line_skip;
+} tbx_conf_t;
+
+typedef struct {
+ tbx_conf_t conf;
+ hts_idx_t *idx;
+ void *dict;
+} tbx_t;
+
+extern tbx_conf_t tbx_conf_gff, tbx_conf_bed, tbx_conf_psltbl, tbx_conf_sam, tbx_conf_vcf;
+
+ #define tbx_itr_destroy(iter) hts_itr_destroy(iter)
+ #define tbx_itr_queryi(tbx, tid, beg, end) hts_itr_query((tbx)->idx, (tid), (beg), (end), tbx_readrec)
+ #define tbx_itr_querys(tbx, s) hts_itr_querys((tbx)->idx, (s), (hts_name2id_f)(tbx_name2id), (tbx), hts_itr_query, tbx_readrec)
+ #define tbx_itr_next(htsfp, tbx, itr, r) hts_itr_next(hts_get_bgzfp(htsfp), (itr), (r), (tbx))
+ #define tbx_bgzf_itr_next(bgzfp, tbx, itr, r) hts_itr_next((bgzfp), (itr), (r), (tbx))
+
+ int tbx_name2id(tbx_t *tbx, const char *ss);
+
+ /* Internal helper function used by tbx_itr_next() */
+ BGZF *hts_get_bgzfp(htsFile *fp);
+ int tbx_readrec(BGZF *fp, void *tbxv, void *sv, int *tid, int *beg, int *end);
+
+ int tbx_index_build(const char *fn, int min_shift, const tbx_conf_t *conf);
+ int tbx_index_build2(const char *fn, const char *fnidx, int min_shift, const tbx_conf_t *conf);
+ tbx_t *tbx_index_load(const char *fn);
+ tbx_t *tbx_index_load2(const char *fn, const char *fnidx);
+ const char **tbx_seqnames(tbx_t *tbx, int *n); // free the array but not the values
+ void tbx_destroy(tbx_t *tbx);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* vcf.h -- VCF/BCF API functions.
+
+ Copyright (C) 2012, 2013 Broad Institute.
+ Copyright (C) 2012-2014 Genome Research Ltd.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+/*
+ todo:
+ - make the function names consistent
+ - provide calls to abstract away structs as much as possible
+ */
+
+#ifndef HTSLIB_VCF_H
+#define HTSLIB_VCF_H
+
+#include <stdint.h>
+#include <limits.h>
+#include <assert.h>
+#include "hts.h"
+#include "kstring.h"
+#include "hts_defs.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+/*****************
+ * Header struct *
+ *****************/
+
+#define BCF_HL_FLT 0 // header line
+#define BCF_HL_INFO 1
+#define BCF_HL_FMT 2
+#define BCF_HL_CTG 3
+#define BCF_HL_STR 4 // structured header line TAG=<A=..,B=..>
+#define BCF_HL_GEN 5 // generic header line
+
+#define BCF_HT_FLAG 0 // header type
+#define BCF_HT_INT 1
+#define BCF_HT_REAL 2
+#define BCF_HT_STR 3
+
+#define BCF_VL_FIXED 0 // variable length
+#define BCF_VL_VAR 1
+#define BCF_VL_A 2
+#define BCF_VL_G 3
+#define BCF_VL_R 4
+
+/* === Dictionary ===
+
+ The header keeps three dictonaries. The first keeps IDs in the
+ "FILTER/INFO/FORMAT" lines, the second keeps the sequence names and lengths
+ in the "contig" lines and the last keeps the sample names. bcf_hdr_t::dict[]
+ is the actual hash table, which is opaque to the end users. In the hash
+ table, the key is the ID or sample name as a C string and the value is a
+ bcf_idinfo_t struct. bcf_hdr_t::id[] points to key-value pairs in the hash
+ table in the order that they appear in the VCF header. bcf_hdr_t::n[] is the
+ size of the hash table or, equivalently, the length of the id[] arrays.
+*/
+
+#define BCF_DT_ID 0 // dictionary type
+#define BCF_DT_CTG 1
+#define BCF_DT_SAMPLE 2
+
+// Complete textual representation of a header line
+typedef struct {
+ int type; // One of the BCF_HL_* type
+ char *key; // The part before '=', i.e. FILTER/INFO/FORMAT/contig/fileformat etc.
+ char *value; // Set only for generic lines, NULL for FILTER/INFO, etc.
+ int nkeys; // Number of structured fields
+ char **keys, **vals; // The key=value pairs
+} bcf_hrec_t;
+
+typedef struct {
+ uint32_t info[3]; // stores Number:20, var:4, Type:4, ColType:4 in info[0..2]
+ // for BCF_HL_FLT,INFO,FMT and contig length in info[0] for BCF_HL_CTG
+ bcf_hrec_t *hrec[3];
+ int id;
+} bcf_idinfo_t;
+
+typedef struct {
+ const char *key;
+ const bcf_idinfo_t *val;
+} bcf_idpair_t;
+
+// Note that bcf_hdr_t structs must always be created via bcf_hdr_init()
+typedef struct {
+ int32_t n[3]; // n:the size of the dictionary block in use, (allocated size, m, is below to preserve ABI)
+ bcf_idpair_t *id[3];
+ void *dict[3]; // ID dictionary, contig dict and sample dict
+ char **samples;
+ bcf_hrec_t **hrec;
+ int nhrec, dirty;
+ int ntransl, *transl[2]; // for bcf_translate()
+ int nsamples_ori; // for bcf_hdr_set_samples()
+ uint8_t *keep_samples;
+ kstring_t mem;
+ int32_t m[3]; // m: allocated size of the dictionary block in use (see n above)
+} bcf_hdr_t;
+
+extern uint8_t bcf_type_shift[];
+
+/**************
+ * VCF record *
+ **************/
+
+#define BCF_BT_NULL 0
+#define BCF_BT_INT8 1
+#define BCF_BT_INT16 2
+#define BCF_BT_INT32 3
+#define BCF_BT_FLOAT 5
+#define BCF_BT_CHAR 7
+
+#define VCF_REF 0
+#define VCF_SNP 1
+#define VCF_MNP 2
+#define VCF_INDEL 4
+#define VCF_OTHER 8
+
+typedef struct {
+ int type, n; // variant type and the number of bases affected, negative for deletions
+} variant_t;
+
+typedef struct {
+ int id; // id: numeric tag id, the corresponding string is bcf_hdr_t::id[BCF_DT_ID][$id].key
+ int n, size, type; // n: number of values per-sample; size: number of bytes per-sample; type: one of BCF_BT_* types
+ uint8_t *p; // same as vptr and vptr_* in bcf_info_t below
+ uint32_t p_len;
+ uint32_t p_off:31, p_free:1;
+} bcf_fmt_t;
+
+typedef struct {
+ int key; // key: numeric tag id, the corresponding string is bcf_hdr_t::id[BCF_DT_ID][$key].key
+ int type, len; // type: one of BCF_BT_* types; len: vector length, 1 for scalars
+ union {
+ int32_t i; // integer value
+ float f; // float value
+ } v1; // only set if $len==1; for easier access
+ uint8_t *vptr; // pointer to data array in bcf1_t->shared.s, excluding the size+type and tag id bytes
+ uint32_t vptr_len; // length of the vptr block or, when set, of the vptr_mod block, excluding offset
+ uint32_t vptr_off:31, // vptr offset, i.e., the size of the INFO key plus size+type bytes
+ vptr_free:1; // indicates that vptr-vptr_off must be freed; set only when modified and the new
+ // data block is bigger than the original
+} bcf_info_t;
+
+
+#define BCF1_DIRTY_ID 1
+#define BCF1_DIRTY_ALS 2
+#define BCF1_DIRTY_FLT 4
+#define BCF1_DIRTY_INF 8
+
+typedef struct {
+ int m_fmt, m_info, m_id, m_als, m_allele, m_flt; // allocated size (high-water mark); do not change
+ int n_flt; // Number of FILTER fields
+ int *flt; // FILTER keys in the dictionary
+ char *id, *als; // ID and REF+ALT block (\0-seperated)
+ char **allele; // allele[0] is the REF (allele[] pointers to the als block); all null terminated
+ bcf_info_t *info; // INFO
+ bcf_fmt_t *fmt; // FORMAT and individual sample
+ variant_t *var; // $var and $var_type set only when set_variant_types called
+ int n_var, var_type;
+ int shared_dirty; // if set, shared.s must be recreated on BCF output
+ int indiv_dirty; // if set, indiv.s must be recreated on BCF output
+} bcf_dec_t;
+
+
+#define BCF_ERR_CTG_UNDEF 1
+#define BCF_ERR_TAG_UNDEF 2
+#define BCF_ERR_NCOLS 4
+#define BCF_ERR_LIMITS 8
+#define BCF_ERR_CHAR 16
+#define BCF_ERR_CTG_INVALID 32
+#define BCF_ERR_TAG_INVALID 64
+
+/*
+ The bcf1_t structure corresponds to one VCF/BCF line. Reading from VCF file
+ is slower because the string is first to be parsed, packed into BCF line
+ (done in vcf_parse), then unpacked into internal bcf1_t structure. If it
+ is known in advance that some of the fields will not be required (notably
+ the sample columns), parsing of these can be skipped by setting max_unpack
+ appropriately.
+ Similarly, it is fast to output a BCF line because the columns (kept in
+ shared.s, indiv.s, etc.) are written directly by bcf_write, whereas a VCF
+ line must be formatted in vcf_format.
+ */
+typedef struct {
+ int32_t rid; // CHROM
+ int32_t pos; // POS
+ int32_t rlen; // length of REF
+ float qual; // QUAL
+ uint32_t n_info:16, n_allele:16;
+ uint32_t n_fmt:8, n_sample:24;
+ kstring_t shared, indiv;
+ bcf_dec_t d; // lazy evaluation: $d is not generated by bcf_read(), but by explicitly calling bcf_unpack()
+ int max_unpack; // Set to BCF_UN_STR, BCF_UN_FLT, or BCF_UN_INFO to boost performance of vcf_parse when some of the fields won't be needed
+ int unpacked; // remember what has been unpacked to allow calling bcf_unpack() repeatedly without redoing the work
+ int unpack_size[3]; // the original block size of ID, REF+ALT and FILTER
+ int errcode; // one of BCF_ERR_* codes
+} bcf1_t;
+
+/*******
+ * API *
+ *******/
+
+ /***********************************************************************
+ * BCF and VCF I/O
+ *
+ * A note about naming conventions: htslib internally represents VCF
+ * records as bcf1_t data structures, therefore most functions are
+ * prefixed with bcf_. There are a few exceptions where the functions must
+ * be aware of both BCF and VCF worlds, such as bcf_parse vs vcf_parse. In
+ * these cases, functions prefixed with bcf_ are more general and work
+ * with both BCF and VCF.
+ *
+ ***********************************************************************/
+
+ /** These macros are defined only for consistency with other parts of htslib */
+ #define bcf_init1() bcf_init()
+ #define bcf_read1(fp,h,v) bcf_read((fp),(h),(v))
+ #define vcf_read1(fp,h,v) vcf_read((fp),(h),(v))
+ #define bcf_write1(fp,h,v) bcf_write((fp),(h),(v))
+ #define vcf_write1(fp,h,v) vcf_write((fp),(h),(v))
+ #define bcf_destroy1(v) bcf_destroy(v)
+ #define bcf_empty1(v) bcf_empty(v)
+ #define vcf_parse1(s,h,v) vcf_parse((s),(h),(v))
+ #define bcf_clear1(v) bcf_clear(v)
+ #define vcf_format1(h,v,s) vcf_format((h),(v),(s))
+
+ /**
+ * bcf_hdr_init() - create an empty BCF header.
+ * @param mode "r" or "w"
+ *
+ * When opened for writing, the mandatory fileFormat and
+ * FILTER=PASS lines are added automatically.
+ */
+ bcf_hdr_t *bcf_hdr_init(const char *mode);
+
+ /** Destroy a BCF header struct */
+ void bcf_hdr_destroy(bcf_hdr_t *h);
+
+ /** Initialize a bcf1_t object; equivalent to calloc(1, sizeof(bcf1_t)) */
+ bcf1_t *bcf_init(void);
+
+ /** Deallocate a bcf1_t object */
+ void bcf_destroy(bcf1_t *v);
+
+ /**
+ * Same as bcf_destroy() but frees only the memory allocated by bcf1_t,
+ * not the bcf1_t object itself.
+ */
+ void bcf_empty(bcf1_t *v);
+
+ /**
+ * Make the bcf1_t object ready for next read. Intended mostly for
+ * internal use, the user should rarely need to call this function
+ * directly.
+ */
+ void bcf_clear(bcf1_t *v);
+
+
+ /** bcf_open and vcf_open mode: please see hts_open() in hts.h */
+ typedef htsFile vcfFile;
+ #define bcf_open(fn, mode) hts_open((fn), (mode))
+ #define vcf_open(fn, mode) hts_open((fn), (mode))
+ #define bcf_close(fp) hts_close(fp)
+ #define vcf_close(fp) hts_close(fp)
+
+ /** Reads VCF or BCF header */
+ bcf_hdr_t *bcf_hdr_read(htsFile *fp);
+
+ /**
+ * bcf_hdr_set_samples() - for more efficient VCF parsing when only one/few samples are needed
+ * @samples: samples to include or exclude from file or as a comma-separated string.
+ * LIST|FILE .. select samples in list/file
+ * ^LIST|FILE .. exclude samples from list/file
+ * - .. include all samples
+ * NULL .. exclude all samples
+ * @is_file: @samples is a file (1) or a comma-separated list (0)
+ *
+ * The bottleneck of VCF reading is parsing of genotype fields. If the
+ * reader knows in advance that only subset of samples is needed (possibly
+ * no samples at all), the performance of bcf_read() can be significantly
+ * improved by calling bcf_hdr_set_samples after bcf_hdr_read().
+ * The function bcf_read() will subset the VCF/BCF records automatically
+ * with the notable exception when reading records via bcf_itr_next().
+ * In this case, bcf_subset_format() must be called explicitly, because
+ * bcf_readrec() does not see the header.
+ *
+ * Returns 0 on success, -1 on error or a positive integer if the list
+ * contains samples not present in the VCF header. In such a case, the
+ * return value is the index of the offending sample.
+ */
+ int bcf_hdr_set_samples(bcf_hdr_t *hdr, const char *samples, int is_file);
+ int bcf_subset_format(const bcf_hdr_t *hdr, bcf1_t *rec);
+
+
+ /** Writes VCF or BCF header */
+ int bcf_hdr_write(htsFile *fp, bcf_hdr_t *h);
+
+ /**
+ * Parse VCF line contained in kstring and populate the bcf1_t struct
+ * The line must not end with \n or \r characters.
+ */
+ int vcf_parse(kstring_t *s, const bcf_hdr_t *h, bcf1_t *v);
+
+ /** The opposite of vcf_parse. It should rarely be called directly, see vcf_write */
+ int vcf_format(const bcf_hdr_t *h, const bcf1_t *v, kstring_t *s);
+
+ /**
+ * bcf_read() - read next VCF or BCF record
+ *
+ * Returns -1 on critical errors, 0 otherwise. On errors which are not
+ * critical for reading, such as missing header definitions, v->errcode is
+ * set to one of BCF_ERR* code and must be checked before calling
+ * vcf_write().
+ */
+ int bcf_read(htsFile *fp, const bcf_hdr_t *h, bcf1_t *v);
+
+ /**
+ * bcf_unpack() - unpack/decode a BCF record (fills the bcf1_t::d field)
+ *
+ * Note that bcf_unpack() must be called even when reading VCF. It is safe
+ * to call the function repeatedly, it will not unpack the same field
+ * twice.
+ */
+ #define BCF_UN_STR 1 // up to ALT inclusive
+ #define BCF_UN_FLT 2 // up to FILTER
+ #define BCF_UN_INFO 4 // up to INFO
+ #define BCF_UN_SHR (BCF_UN_STR|BCF_UN_FLT|BCF_UN_INFO) // all shared information
+ #define BCF_UN_FMT 8 // unpack format and each sample
+ #define BCF_UN_IND BCF_UN_FMT // a synonymo of BCF_UN_FMT
+ #define BCF_UN_ALL (BCF_UN_SHR|BCF_UN_FMT) // everything
+ int bcf_unpack(bcf1_t *b, int which);
+
+ /*
+ * bcf_dup() - create a copy of BCF record.
+ *
+ * Note that bcf_unpack() must be called on the returned copy as if it was
+ * obtained from bcf_read(). Also note that bcf_dup() calls bcf_sync1(src)
+ * internally to reflect any changes made by bcf_update_* functions.
+ */
+ bcf1_t *bcf_dup(bcf1_t *src);
+ bcf1_t *bcf_copy(bcf1_t *dst, bcf1_t *src);
+
+ /**
+ * bcf_write() - write one VCF or BCF record. The type is determined at the open() call.
+ */
+ int bcf_write(htsFile *fp, bcf_hdr_t *h, bcf1_t *v);
+
+ /**
+ * The following functions work only with VCFs and should rarely be called
+ * directly. Usually one wants to use their bcf_* alternatives, which work
+ * transparently with both VCFs and BCFs.
+ */
+ bcf_hdr_t *vcf_hdr_read(htsFile *fp);
+ int vcf_hdr_write(htsFile *fp, const bcf_hdr_t *h);
+ int vcf_read(htsFile *fp, const bcf_hdr_t *h, bcf1_t *v);
+ int vcf_write(htsFile *fp, const bcf_hdr_t *h, bcf1_t *v);
+
+ /** Helper function for the bcf_itr_next() macro; internal use, ignore it */
+ int bcf_readrec(BGZF *fp, void *null, void *v, int *tid, int *beg, int *end);
+
+
+
+ /**************************************************************************
+ * Header querying and manipulation routines
+ **************************************************************************/
+
+ /** Create a new header using the supplied template */
+ bcf_hdr_t *bcf_hdr_dup(const bcf_hdr_t *hdr);
+
+ /**
+ * Copy header lines from src to dst if not already present in dst. See also bcf_translate().
+ * Returns 0 on success or sets a bit on error:
+ * 1 .. conflicting definitions of tag length
+ * // todo
+ */
+ int bcf_hdr_combine(bcf_hdr_t *dst, const bcf_hdr_t *src) HTS_DEPRECATED("Please use bcf_hdr_merge instead");
+
+ /**
+ * bcf_hdr_merge() - copy header lines from src to dst, see also bcf_translate()
+ * @param dst: the destination header to be merged into, NULL on the first pass
+ * @param src: the source header
+ *
+ * Notes:
+ * - use as:
+ * bcf_hdr_t *dst = NULL;
+ * for (i=0; i<nsrc; i++) dst = bcf_hdr_merge(dst,src[i]);
+ *
+ * - bcf_hdr_merge() replaces bcf_hdr_combine() which had a problem when
+ * combining multiple BCF headers. The current bcf_hdr_combine()
+ * does not have this problem, but became slow when used for many files.
+ */
+ bcf_hdr_t *bcf_hdr_merge(bcf_hdr_t *dst, const bcf_hdr_t *src);
+
+ /**
+ * bcf_hdr_add_sample() - add a new sample.
+ * @param sample: sample name to be added
+ */
+ int bcf_hdr_add_sample(bcf_hdr_t *hdr, const char *sample);
+
+ /** Read VCF header from a file and update the header */
+ int bcf_hdr_set(bcf_hdr_t *hdr, const char *fname);
+
+ /** Returns formatted header (newly allocated string) and its length,
+ * excluding the terminating \0. If is_bcf parameter is unset, IDX
+ * fields are discarded.
+ */
+ char *bcf_hdr_fmt_text(const bcf_hdr_t *hdr, int is_bcf, int *len);
+
+ /** Append new VCF header line, returns 0 on success */
+ int bcf_hdr_append(bcf_hdr_t *h, const char *line);
+ int bcf_hdr_printf(bcf_hdr_t *h, const char *format, ...);
+
+ /** VCF version, e.g. VCFv4.2 */
+ const char *bcf_hdr_get_version(const bcf_hdr_t *hdr);
+ void bcf_hdr_set_version(bcf_hdr_t *hdr, const char *version);
+
+ /**
+ * bcf_hdr_remove() - remove VCF header tag
+ * @param type: one of BCF_HL_*
+ * @param key: tag name or NULL to remove all tags of the given type
+ */
+ void bcf_hdr_remove(bcf_hdr_t *h, int type, const char *key);
+
+ /**
+ * bcf_hdr_subset() - creates a new copy of the header removing unwanted samples
+ * @param n: number of samples to keep
+ * @param samples: names of the samples to keep
+ * @param imap: mapping from index in @samples to the sample index in the original file
+ *
+ * Sample names not present in h0 are ignored. The number of unmatched samples can be checked
+ * by comparing n and bcf_hdr_nsamples(out_hdr).
+ * This function can be used to reorder samples.
+ * See also bcf_subset() which subsets individual records.
+ */
+ bcf_hdr_t *bcf_hdr_subset(const bcf_hdr_t *h0, int n, char *const* samples, int *imap);
+
+ /** Creates a list of sequence names. It is up to the caller to free the list (but not the sequence names) */
+ const char **bcf_hdr_seqnames(const bcf_hdr_t *h, int *nseqs);
+
+ /** Get number of samples */
+ #define bcf_hdr_nsamples(hdr) (hdr)->n[BCF_DT_SAMPLE]
+
+
+ /** The following functions are for internal use and should rarely be called directly */
+ int bcf_hdr_parse(bcf_hdr_t *hdr, char *htxt);
+ int bcf_hdr_sync(bcf_hdr_t *h);
+ bcf_hrec_t *bcf_hdr_parse_line(const bcf_hdr_t *h, const char *line, int *len);
+ void bcf_hrec_format(const bcf_hrec_t *hrec, kstring_t *str);
+ int bcf_hdr_add_hrec(bcf_hdr_t *hdr, bcf_hrec_t *hrec);
+ /**
+ * bcf_hdr_get_hrec() - get header line info
+ * @param type: one of the BCF_HL_* types: FLT,INFO,FMT,CTG,STR,GEN
+ * @param key: the header key for generic lines (e.g. "fileformat"), any field
+ * for structured lines, typically "ID".
+ * @param value: the value which pairs with key. Can be be NULL for BCF_HL_GEN
+ * @param str_class: the class of BCF_HL_STR line (e.g. "ALT" or "SAMPLE"), otherwise NULL
+ */
+ bcf_hrec_t *bcf_hdr_get_hrec(const bcf_hdr_t *hdr, int type, const char *key, const char *value, const char *str_class);
+ bcf_hrec_t *bcf_hrec_dup(bcf_hrec_t *hrec);
+ void bcf_hrec_add_key(bcf_hrec_t *hrec, const char *str, int len);
+ void bcf_hrec_set_val(bcf_hrec_t *hrec, int i, const char *str, int len, int is_quoted);
+ int bcf_hrec_find_key(bcf_hrec_t *hrec, const char *key);
+ void hrec_add_idx(bcf_hrec_t *hrec, int idx);
+ void bcf_hrec_destroy(bcf_hrec_t *hrec);
+
+
+
+ /**************************************************************************
+ * Individual record querying and manipulation routines
+ **************************************************************************/
+
+ /** See the description of bcf_hdr_subset() */
+ int bcf_subset(const bcf_hdr_t *h, bcf1_t *v, int n, int *imap);
+
+ /**
+ * bcf_translate() - translate tags ids to be consistent with different header. This function
+ * is useful when lines from multiple VCF need to be combined.
+ * @dst_hdr: the destination header, to be used in bcf_write(), see also bcf_hdr_combine()
+ * @src_hdr: the source header, used in bcf_read()
+ * @src_line: line obtained by bcf_read()
+ */
+ int bcf_translate(const bcf_hdr_t *dst_hdr, bcf_hdr_t *src_hdr, bcf1_t *src_line);
+
+ /**
+ * bcf_get_variant_type[s]() - returns one of VCF_REF, VCF_SNP, etc
+ */
+ int bcf_get_variant_types(bcf1_t *rec);
+ int bcf_get_variant_type(bcf1_t *rec, int ith_allele);
+ int bcf_is_snp(bcf1_t *v);
+
+ /**
+ * bcf_update_filter() - sets the FILTER column
+ * @flt_ids: The filter IDs to set, numeric IDs returned by bcf_hdr_id2int(hdr, BCF_DT_ID, "PASS")
+ * @n: Number of filters. If n==0, all filters are removed
+ */
+ int bcf_update_filter(const bcf_hdr_t *hdr, bcf1_t *line, int *flt_ids, int n);
+ /**
+ * bcf_add_filter() - adds to the FILTER column
+ * @flt_id: filter ID to add, numeric ID returned by bcf_hdr_id2int(hdr, BCF_DT_ID, "PASS")
+ *
+ * If flt_id is PASS, all existing filters are removed first. If other than PASS, existing PASS is removed.
+ */
+ int bcf_add_filter(const bcf_hdr_t *hdr, bcf1_t *line, int flt_id);
+ /**
+ * bcf_remove_filter() - removes from the FILTER column
+ * @flt_id: filter ID to remove, numeric ID returned by bcf_hdr_id2int(hdr, BCF_DT_ID, "PASS")
+ * @pass: when set to 1 and no filters are present, set to PASS
+ */
+ int bcf_remove_filter(const bcf_hdr_t *hdr, bcf1_t *line, int flt_id, int pass);
+ /**
+ * Returns 1 if present, 0 if absent, or -1 if filter does not exist. "PASS" and "." can be used interchangeably.
+ */
+ int bcf_has_filter(const bcf_hdr_t *hdr, bcf1_t *line, char *filter);
+ /**
+ * bcf_update_alleles() and bcf_update_alleles_str() - update REF and ALLT column
+ * @alleles: Array of alleles
+ * @nals: Number of alleles
+ * @alleles_string: Comma-separated alleles, starting with the REF allele
+ */
+ int bcf_update_alleles(const bcf_hdr_t *hdr, bcf1_t *line, const char **alleles, int nals);
+ int bcf_update_alleles_str(const bcf_hdr_t *hdr, bcf1_t *line, const char *alleles_string);
+
+ /**
+ * bcf_update_id() - sets new ID string
+ * bcf_add_id() - adds to the ID string checking for duplicates
+ */
+ int bcf_update_id(const bcf_hdr_t *hdr, bcf1_t *line, const char *id);
+ int bcf_add_id(const bcf_hdr_t *hdr, bcf1_t *line, const char *id);
+
+ /*
+ * bcf_update_info_*() - functions for updating INFO fields
+ * @hdr: the BCF header
+ * @line: VCF line to be edited
+ * @key: the INFO tag to be updated
+ * @values: pointer to the array of values. Pass NULL to remove the tag.
+ * @n: number of values in the array. When set to 0, the INFO tag is removed
+ *
+ * The @string in bcf_update_info_flag() is optional, @n indicates whether
+ * the flag is set or removed.
+ *
+ * Returns 0 on success or negative value on error.
+ */
+ #define bcf_update_info_int32(hdr,line,key,values,n) bcf_update_info((hdr),(line),(key),(values),(n),BCF_HT_INT)
+ #define bcf_update_info_float(hdr,line,key,values,n) bcf_update_info((hdr),(line),(key),(values),(n),BCF_HT_REAL)
+ #define bcf_update_info_flag(hdr,line,key,string,n) bcf_update_info((hdr),(line),(key),(string),(n),BCF_HT_FLAG)
+ #define bcf_update_info_string(hdr,line,key,string) bcf_update_info((hdr),(line),(key),(string),1,BCF_HT_STR)
+ int bcf_update_info(const bcf_hdr_t *hdr, bcf1_t *line, const char *key, const void *values, int n, int type);
+
+ /*
+ * bcf_update_format_*() - functions for updating FORMAT fields
+ * @values: pointer to the array of values, the same number of elements
+ * is expected for each sample. Missing values must be padded
+ * with bcf_*_missing or bcf_*_vector_end values.
+ * @n: number of values in the array. If n==0, existing tag is removed.
+ *
+ * The function bcf_update_format_string() is a higher-level (slower) variant of
+ * bcf_update_format_char(). The former accepts array of \0-terminated strings
+ * whereas the latter requires that the strings are collapsed into a single array
+ * of fixed-length strings. In case of strings with variable length, shorter strings
+ * can be \0-padded. Note that the collapsed strings passed to bcf_update_format_char()
+ * are not \0-terminated.
+ *
+ * Returns 0 on success or negative value on error.
+ */
+ #define bcf_update_format_int32(hdr,line,key,values,n) bcf_update_format((hdr),(line),(key),(values),(n),BCF_HT_INT)
+ #define bcf_update_format_float(hdr,line,key,values,n) bcf_update_format((hdr),(line),(key),(values),(n),BCF_HT_REAL)
+ #define bcf_update_format_char(hdr,line,key,values,n) bcf_update_format((hdr),(line),(key),(values),(n),BCF_HT_STR)
+ #define bcf_update_genotypes(hdr,line,gts,n) bcf_update_format((hdr),(line),"GT",(gts),(n),BCF_HT_INT) // See bcf_gt_ macros below
+ int bcf_update_format_string(const bcf_hdr_t *hdr, bcf1_t *line, const char *key, const char **values, int n);
+ int bcf_update_format(const bcf_hdr_t *hdr, bcf1_t *line, const char *key, const void *values, int n, int type);
+
+ // Macros for setting genotypes correctly, for use with bcf_update_genotypes only; idx corresponds
+ // to VCF's GT (1-based index to ALT or 0 for the reference allele) and val is the opposite, obtained
+ // from bcf_get_genotypes() below.
+ #define bcf_gt_phased(idx) (((idx)+1)<<1|1)
+ #define bcf_gt_unphased(idx) (((idx)+1)<<1)
+ #define bcf_gt_missing 0
+ #define bcf_gt_is_missing(val) ((val)>>1 ? 0 : 1)
+ #define bcf_gt_is_phased(idx) ((idx)&1)
+ #define bcf_gt_allele(val) (((val)>>1)-1)
+
+ /** Conversion between alleles indexes to Number=G genotype index (assuming diploid, all 0-based) */
+ #define bcf_alleles2gt(a,b) ((a)>(b)?((a)*((a)+1)/2+(b)):((b)*((b)+1)/2+(a)))
+ static inline void bcf_gt2alleles(int igt, int *a, int *b)
+ {
+ int k = 0, dk = 1;
+ while ( k<igt ) { dk++; k += dk; }
+ *b = dk - 1; *a = igt - k + *b;
+ }
+
+ /**
+ * bcf_get_fmt() - returns pointer to FORMAT's field data
+ * @header: for access to BCF_DT_ID dictionary
+ * @line: VCF line obtained from vcf_parse1
+ * @fmt: one of GT,PL,...
+ *
+ * Returns bcf_fmt_t* if the call succeeded, or returns NULL when the field
+ * is not available.
+ */
+ bcf_fmt_t *bcf_get_fmt(const bcf_hdr_t *hdr, bcf1_t *line, const char *key);
+ bcf_info_t *bcf_get_info(const bcf_hdr_t *hdr, bcf1_t *line, const char *key);
+
+ /**
+ * bcf_get_*_id() - returns pointer to FORMAT/INFO field data given the header index instead of the string ID
+ * @line: VCF line obtained from vcf_parse1
+ * @id: The header index for the tag, obtained from bcf_hdr_id2int()
+ *
+ * Returns bcf_fmt_t* / bcf_info_t*. These functions do not check if the index is valid
+ * as their goal is to avoid the header lookup.
+ */
+ bcf_fmt_t *bcf_get_fmt_id(bcf1_t *line, const int id);
+ bcf_info_t *bcf_get_info_id(bcf1_t *line, const int id);
+
+ /**
+ * bcf_get_info_*() - get INFO values, integers or floats
+ * @hdr: BCF header
+ * @line: BCF record
+ * @tag: INFO tag to retrieve
+ * @dst: *dst is pointer to a memory location, can point to NULL
+ * @ndst: pointer to the size of allocated memory
+ *
+ * Returns negative value on error or the number of written values on
+ * success. bcf_get_info_string() returns on success the number of
+ * characters written excluding the null-terminating byte. bcf_get_info_flag()
+ * returns 1 when flag is set or 0 if not.
+ *
+ * List of return codes:
+ * -1 .. no such INFO tag defined in the header
+ * -2 .. clash between types defined in the header and encountered in the VCF record
+ * -3 .. tag is not present in the VCF record
+ */
+ #define bcf_get_info_int32(hdr,line,tag,dst,ndst) bcf_get_info_values(hdr,line,tag,(void**)(dst),ndst,BCF_HT_INT)
+ #define bcf_get_info_float(hdr,line,tag,dst,ndst) bcf_get_info_values(hdr,line,tag,(void**)(dst),ndst,BCF_HT_REAL)
+ #define bcf_get_info_string(hdr,line,tag,dst,ndst) bcf_get_info_values(hdr,line,tag,(void**)(dst),ndst,BCF_HT_STR)
+ #define bcf_get_info_flag(hdr,line,tag,dst,ndst) bcf_get_info_values(hdr,line,tag,(void**)(dst),ndst,BCF_HT_FLAG)
+ int bcf_get_info_values(const bcf_hdr_t *hdr, bcf1_t *line, const char *tag, void **dst, int *ndst, int type);
+
+ /**
+ * bcf_get_format_*() - same as bcf_get_info*() above
+ *
+ * The function bcf_get_format_string() is a higher-level (slower) variant of bcf_get_format_char().
+ * see the description of bcf_update_format_string() and bcf_update_format_char() above.
+ * Unlike other bcf_get_format__*() functions, bcf_get_format_string() allocates two arrays:
+ * a single block of \0-terminated strings collapsed into a single array and an array of pointers
+ * to these strings. Both arrays must be cleaned by the user.
+ *
+ * Returns negative value on error or the number of written values on success.
+ *
+ * Example:
+ * int ndst = 0; char **dst = NULL;
+ * if ( bcf_get_format_string(hdr, line, "XX", &dst, &ndst) > 0 )
+ * for (i=0; i<bcf_hdr_nsamples(hdr); i++) printf("%s\n", dst[i]);
+ * free(dst[0]); free(dst);
+ *
+ * Example:
+ * int ngt, *gt_arr = NULL, ngt_arr = 0;
+ * ngt = bcf_get_genotypes(hdr, line, >_arr, &ngt_arr);
+ */
+ #define bcf_get_format_int32(hdr,line,tag,dst,ndst) bcf_get_format_values(hdr,line,tag,(void**)(dst),ndst,BCF_HT_INT)
+ #define bcf_get_format_float(hdr,line,tag,dst,ndst) bcf_get_format_values(hdr,line,tag,(void**)(dst),ndst,BCF_HT_REAL)
+ #define bcf_get_format_char(hdr,line,tag,dst,ndst) bcf_get_format_values(hdr,line,tag,(void**)(dst),ndst,BCF_HT_STR)
+ #define bcf_get_genotypes(hdr,line,dst,ndst) bcf_get_format_values(hdr,line,"GT",(void**)(dst),ndst,BCF_HT_INT)
+ int bcf_get_format_string(const bcf_hdr_t *hdr, bcf1_t *line, const char *tag, char ***dst, int *ndst);
+ int bcf_get_format_values(const bcf_hdr_t *hdr, bcf1_t *line, const char *tag, void **dst, int *ndst, int type);
+
+
+
+ /**************************************************************************
+ * Helper functions
+ **************************************************************************/
+
+ /**
+ * bcf_hdr_id2int() - Translates string into numeric ID
+ * bcf_hdr_int2id() - Translates numeric ID into string
+ * @type: one of BCF_DT_ID, BCF_DT_CTG, BCF_DT_SAMPLE
+ * @id: tag name, such as: PL, DP, GT, etc.
+ *
+ * Returns -1 if string is not in dictionary, otherwise numeric ID which identifies
+ * fields in BCF records.
+ */
+ int bcf_hdr_id2int(const bcf_hdr_t *hdr, int type, const char *id);
+ #define bcf_hdr_int2id(hdr,type,int_id) ((hdr)->id[type][int_id].key)
+
+ /**
+ * bcf_hdr_name2id() - Translates sequence names (chromosomes) into numeric ID
+ * bcf_hdr_id2name() - Translates numeric ID to sequence name
+ */
+ static inline int bcf_hdr_name2id(const bcf_hdr_t *hdr, const char *id) { return bcf_hdr_id2int(hdr, BCF_DT_CTG, id); }
+ static inline const char *bcf_hdr_id2name(const bcf_hdr_t *hdr, int rid) { return hdr->id[BCF_DT_CTG][rid].key; }
+ static inline const char *bcf_seqname(const bcf_hdr_t *hdr, bcf1_t *rec) { return hdr->id[BCF_DT_CTG][rec->rid].key; }
+
+ /**
+ * bcf_hdr_id2*() - Macros for accessing bcf_idinfo_t
+ * @type: one of BCF_HL_FLT, BCF_HL_INFO, BCF_HL_FMT
+ * @int_id: return value of bcf_hdr_id2int, must be >=0
+ *
+ * The returned values are:
+ * bcf_hdr_id2length .. whether the number of values is fixed or variable, one of BCF_VL_*
+ * bcf_hdr_id2number .. the number of values, 0xfffff for variable length fields
+ * bcf_hdr_id2type .. the field type, one of BCF_HT_*
+ * bcf_hdr_id2coltype .. the column type, one of BCF_HL_*
+ *
+ * Notes: Prior to using the macros, the presence of the info should be
+ * tested with bcf_hdr_idinfo_exists().
+ */
+ #define bcf_hdr_id2length(hdr,type,int_id) ((hdr)->id[BCF_DT_ID][int_id].val->info[type]>>8 & 0xf)
+ #define bcf_hdr_id2number(hdr,type,int_id) ((hdr)->id[BCF_DT_ID][int_id].val->info[type]>>12)
+ #define bcf_hdr_id2type(hdr,type,int_id) ((hdr)->id[BCF_DT_ID][int_id].val->info[type]>>4 & 0xf)
+ #define bcf_hdr_id2coltype(hdr,type,int_id) ((hdr)->id[BCF_DT_ID][int_id].val->info[type] & 0xf)
+ #define bcf_hdr_idinfo_exists(hdr,type,int_id) ((int_id<0 || bcf_hdr_id2coltype(hdr,type,int_id)==0xf) ? 0 : 1)
+ #define bcf_hdr_id2hrec(hdr,dict_type,col_type,int_id) ((hdr)->id[(dict_type)==BCF_DT_CTG?BCF_DT_CTG:BCF_DT_ID][int_id].val->hrec[(dict_type)==BCF_DT_CTG?0:(col_type)])
+
+ void bcf_fmt_array(kstring_t *s, int n, int type, void *data);
+ uint8_t *bcf_fmt_sized_array(kstring_t *s, uint8_t *ptr);
+
+ void bcf_enc_vchar(kstring_t *s, int l, const char *a);
+ void bcf_enc_vint(kstring_t *s, int n, int32_t *a, int wsize);
+ void bcf_enc_vfloat(kstring_t *s, int n, float *a);
+
+
+ /**************************************************************************
+ * BCF index
+ *
+ * Note that these functions work with BCFs only. See synced_bcf_reader.h
+ * which provides (amongst other things) an API to work transparently with
+ * both indexed BCFs and VCFs.
+ **************************************************************************/
+
+ #define bcf_itr_destroy(iter) hts_itr_destroy(iter)
+ #define bcf_itr_queryi(idx, tid, beg, end) hts_itr_query((idx), (tid), (beg), (end), bcf_readrec)
+ #define bcf_itr_querys(idx, hdr, s) hts_itr_querys((idx), (s), (hts_name2id_f)(bcf_hdr_name2id), (hdr), hts_itr_query, bcf_readrec)
+ #define bcf_itr_next(htsfp, itr, r) hts_itr_next((htsfp)->fp.bgzf, (itr), (r), 0)
+ #define bcf_index_load(fn) hts_idx_load(fn, HTS_FMT_CSI)
+ #define bcf_index_seqnames(idx, hdr, nptr) hts_idx_seqnames((idx),(nptr),(hts_id2name_f)(bcf_hdr_id2name),(hdr))
+
+ hts_idx_t *bcf_index_load2(const char *fn, const char *fnidx);
+ int bcf_index_build(const char *fn, int min_shift);
+ int bcf_index_build2(const char *fn, const char *fnidx, int min_shift);
+
+/*******************
+ * Typed value I/O *
+ *******************/
+
+/*
+ Note that in contrast with BCFv2.1 specification, HTSlib implementation
+ allows missing values in vectors. For integer types, the values 0x80,
+ 0x8000, 0x80000000 are interpreted as missing values and 0x81, 0x8001,
+ 0x80000001 as end-of-vector indicators. Similarly for floats, the value of
+ 0x7F800001 is interpreted as a missing value and 0x7F800002 as an
+ end-of-vector indicator.
+ Note that the end-of-vector byte is not part of the vector.
+
+ This trial BCF version (v2.2) is compatible with the VCF specification and
+ enables to handle correctly vectors with different ploidy in presence of
+ missing values.
+ */
+#define bcf_int8_vector_end (INT8_MIN+1)
+#define bcf_int16_vector_end (INT16_MIN+1)
+#define bcf_int32_vector_end (INT32_MIN+1)
+#define bcf_str_vector_end 0
+#define bcf_int8_missing INT8_MIN
+#define bcf_int16_missing INT16_MIN
+#define bcf_int32_missing INT32_MIN
+#define bcf_str_missing 0x07
+extern uint32_t bcf_float_vector_end;
+extern uint32_t bcf_float_missing;
+static inline void bcf_float_set(float *ptr, uint32_t value)
+{
+ union { uint32_t i; float f; } u;
+ u.i = value;
+ *ptr = u.f;
+}
+#define bcf_float_set_vector_end(x) bcf_float_set(&(x),bcf_float_vector_end)
+#define bcf_float_set_missing(x) bcf_float_set(&(x),bcf_float_missing)
+static inline int bcf_float_is_missing(float f)
+{
+ union { uint32_t i; float f; } u;
+ u.f = f;
+ return u.i==bcf_float_missing ? 1 : 0;
+}
+static inline int bcf_float_is_vector_end(float f)
+{
+ union { uint32_t i; float f; } u;
+ u.f = f;
+ return u.i==bcf_float_vector_end ? 1 : 0;
+}
+
+static inline void bcf_format_gt(bcf_fmt_t *fmt, int isample, kstring_t *str)
+{
+ #define BRANCH(type_t, missing, vector_end) { \
+ type_t *ptr = (type_t*) (fmt->p + isample*fmt->size); \
+ int i; \
+ for (i=0; i<fmt->n && ptr[i]!=vector_end; i++) \
+ { \
+ if ( i ) kputc("/|"[ptr[i]&1], str); \
+ if ( !(ptr[i]>>1) ) kputc('.', str); \
+ else kputw((ptr[i]>>1) - 1, str); \
+ } \
+ if (i == 0) kputc('.', str); \
+ }
+ switch (fmt->type) {
+ case BCF_BT_INT8: BRANCH(int8_t, bcf_int8_missing, bcf_int8_vector_end); break;
+ case BCF_BT_INT16: BRANCH(int16_t, bcf_int16_missing, bcf_int16_vector_end); break;
+ case BCF_BT_INT32: BRANCH(int32_t, bcf_int32_missing, bcf_int32_vector_end); break;
+ case BCF_BT_NULL: kputc('.', str); break;
+ default: fprintf(stderr,"FIXME: type %d in bcf_format_gt?\n", fmt->type); abort(); break;
+ }
+ #undef BRANCH
+}
+
+static inline void bcf_enc_size(kstring_t *s, int size, int type)
+{
+ if (size >= 15) {
+ kputc(15<<4|type, s);
+ if (size >= 128) {
+ if (size >= 32768) {
+ int32_t x = size;
+ kputc(1<<4|BCF_BT_INT32, s);
+ kputsn((char*)&x, 4, s);
+ } else {
+ int16_t x = size;
+ kputc(1<<4|BCF_BT_INT16, s);
+ kputsn((char*)&x, 2, s);
+ }
+ } else {
+ kputc(1<<4|BCF_BT_INT8, s);
+ kputc(size, s);
+ }
+ } else kputc(size<<4|type, s);
+}
+
+static inline int bcf_enc_inttype(long x)
+{
+ if (x <= INT8_MAX && x > bcf_int8_missing) return BCF_BT_INT8;
+ if (x <= INT16_MAX && x > bcf_int16_missing) return BCF_BT_INT16;
+ return BCF_BT_INT32;
+}
+
+static inline void bcf_enc_int1(kstring_t *s, int32_t x)
+{
+ if (x == bcf_int32_vector_end) {
+ bcf_enc_size(s, 1, BCF_BT_INT8);
+ kputc(bcf_int8_vector_end, s);
+ } else if (x == bcf_int32_missing) {
+ bcf_enc_size(s, 1, BCF_BT_INT8);
+ kputc(bcf_int8_missing, s);
+ } else if (x <= INT8_MAX && x > bcf_int8_missing) {
+ bcf_enc_size(s, 1, BCF_BT_INT8);
+ kputc(x, s);
+ } else if (x <= INT16_MAX && x > bcf_int16_missing) {
+ int16_t z = x;
+ bcf_enc_size(s, 1, BCF_BT_INT16);
+ kputsn((char*)&z, 2, s);
+ } else {
+ int32_t z = x;
+ bcf_enc_size(s, 1, BCF_BT_INT32);
+ kputsn((char*)&z, 4, s);
+ }
+}
+
+static inline int32_t bcf_dec_int1(const uint8_t *p, int type, uint8_t **q)
+{
+ if (type == BCF_BT_INT8) {
+ *q = (uint8_t*)p + 1;
+ return *(int8_t*)p;
+ } else if (type == BCF_BT_INT16) {
+ *q = (uint8_t*)p + 2;
+ return *(int16_t*)p;
+ } else {
+ *q = (uint8_t*)p + 4;
+ return *(int32_t*)p;
+ }
+}
+
+static inline int32_t bcf_dec_typed_int1(const uint8_t *p, uint8_t **q)
+{
+ return bcf_dec_int1(p + 1, *p&0xf, q);
+}
+
+static inline int32_t bcf_dec_size(const uint8_t *p, uint8_t **q, int *type)
+{
+ *type = *p & 0xf;
+ if (*p>>4 != 15) {
+ *q = (uint8_t*)p + 1;
+ return *p>>4;
+ } else return bcf_dec_typed_int1(p + 1, q);
+}
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* vcf_sweep.h -- forward/reverse sweep API.
+
+ Copyright (C) 2013 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_VCF_SWEEP_H
+#define HTSLIB_VCF_SWEEP_H
+
+#include "hts.h"
+#include "vcf.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+typedef struct _bcf_sweep_t bcf_sweep_t;
+
+bcf_sweep_t *bcf_sweep_init(const char *fname);
+void bcf_sweep_destroy(bcf_sweep_t *sw);
+bcf_hdr_t *bcf_sweep_hdr(bcf_sweep_t *sw);
+bcf1_t *bcf_sweep_fwd(bcf_sweep_t *sw);
+bcf1_t *bcf_sweep_bwd(bcf_sweep_t *sw);
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+/* vcfutils.h -- allele-related utility functions.
+
+ Copyright (C) 2012, 2013, 2015 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#ifndef HTSLIB_VCFUTILS_H
+#define HTSLIB_VCFUTILS_H
+
+#include "vcf.h"
+
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+struct kbitset_t;
+
+/**
+ * bcf_trim_alleles() - remove ALT alleles unused in genotype fields
+ * @header: for access to BCF_DT_ID dictionary
+ * @line: VCF line obtain from vcf_parse1
+ *
+ * Returns the number of removed alleles on success or negative
+ * on error:
+ * -1 .. some allele index is out of bounds
+ */
+int bcf_trim_alleles(const bcf_hdr_t *header, bcf1_t *line);
+
+/**
+ * bcf_remove_alleles() - remove ALT alleles according to bitmask @mask
+ * @header: for access to BCF_DT_ID dictionary
+ * @line: VCF line obtained from vcf_parse1
+ * @mask: alleles to remove
+ *
+ * If you have more than 31 alleles, then the integer bit mask will
+ * overflow, so use bcf_remove_allele_set instead
+ */
+void bcf_remove_alleles(const bcf_hdr_t *header, bcf1_t *line, int mask);
+
+/**
+ * bcf_remove_allele_set() - remove ALT alleles according to bitset @rm_set
+ * @header: for access to BCF_DT_ID dictionary
+ * @line: VCF line obtained from vcf_parse1
+ * @rm_set: pointer to kbitset_t object with bits set for allele
+ * indexes to remove
+ *
+ * Number=A,R,G INFO and FORMAT fields will be updated accordingly.
+ */
+void bcf_remove_allele_set(const bcf_hdr_t *header, bcf1_t *line, const struct kbitset_t *rm_set);
+
+/**
+ * bcf_calc_ac() - calculate the number of REF and ALT alleles
+ * @header: for access to BCF_DT_ID dictionary
+ * @line: VCF line obtained from vcf_parse1
+ * @ac: array of length line->n_allele
+ * @which: determine if INFO/AN,AC and indv fields be used
+ *
+ * Returns 1 if the call succeeded, or 0 if the value could not
+ * be determined.
+ *
+ * The value of @which determines if existing INFO/AC,AN can be
+ * used (BCF_UN_INFO) and and if indv fields can be splitted
+ * (BCF_UN_FMT).
+ */
+int bcf_calc_ac(const bcf_hdr_t *header, bcf1_t *line, int *ac, int which);
+
+
+/**
+ * bcf_gt_type() - determines type of the genotype
+ * @fmt_ptr: the GT format field as set for example by set_fmt_ptr
+ * @isample: sample index (starting from 0)
+ * @ial: index of the 1st non-reference allele (starting from 1)
+ * @jal: index of the 2nd non-reference allele (starting from 1)
+ *
+ * Returns the type of the genotype (one of GT_HOM_RR, GT_HET_RA,
+ * GT_HOM_AA, GT_HET_AA, GT_HAPL_R, GT_HAPL_A or GT_UNKN). If $ial
+ * is not NULL and the genotype has one or more non-reference
+ * alleles, $ial will be set. In case of GT_HET_AA, $ial is the
+ * position of the allele which appeared first in ALT. If $jal is
+ * not null and the genotype is GT_HET_AA, $jal will be set and is
+ * the position of the second allele in ALT.
+ */
+#define GT_HOM_RR 0 // note: the actual value of GT_* matters, used in dosage r2 calculation
+#define GT_HOM_AA 1
+#define GT_HET_RA 2
+#define GT_HET_AA 3
+#define GT_HAPL_R 4
+#define GT_HAPL_A 5
+#define GT_UNKN 6
+int bcf_gt_type(bcf_fmt_t *fmt_ptr, int isample, int *ial, int *jal);
+
+static inline int bcf_acgt2int(char c)
+{
+ if ( (int)c>96 ) c -= 32;
+ if ( c=='A' ) return 0;
+ if ( c=='C' ) return 1;
+ if ( c=='G' ) return 2;
+ if ( c=='T' ) return 3;
+ return -1;
+}
+
+#define bcf_int2acgt(i) "ACGT"[i]
+
+/**
+ * bcf_ij2G() - common task: allele indexes to Number=G index (diploid)
+ * @i,j: allele indexes, 0-based, i<=j
+ *
+ * Returns index to the Number=G diploid array
+ */
+#define bcf_ij2G(i, j) ((j)*((j)+1)/2+(i))
+
+#ifdef __cplusplus
+}
+#endif
+
+#endif
--- /dev/null
+# Makefile variables useful for third-party code using htslib's public API.
+#
+# Copyright (C) 2013-2016 Genome Research Ltd.
+#
+# Author: John Marshall <jm18@sanger.ac.uk>
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in
+# all copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+# DEALINGS IN THE SOFTWARE.
+
+# These variables can be used to express dependencies on htslib headers.
+# See htslib.mk for details.
+
+htslib_bgzf_h = $(HTSPREFIX)htslib/bgzf.h $(htslib_hts_defs_h)
+htslib_cram_h = $(HTSPREFIX)htslib/cram.h $(htslib_hts_h)
+htslib_faidx_h = $(HTSPREFIX)htslib/faidx.h $(htslib_hts_defs_h)
+htslib_hfile_h = $(HTSPREFIX)htslib/hfile.h $(htslib_hts_defs_h)
+htslib_hts_h = $(HTSPREFIX)htslib/hts.h $(htslib_hts_defs_h)
+htslib_hts_defs_h = $(HTSPREFIX)htslib/hts_defs.h
+htslib_kbitset_h = $(HTSPREFIX)htslib/kbitset.h
+htslib_kfunc_h = $(HTSPREFIX)htslib/kfunc.h
+htslib_khash_h = $(HTSPREFIX)htslib/khash.h
+htslib_khash_str2int_h = $(HTSPREFIX)htslib/khash_str2int.h $(htslib_khash_h)
+htslib_klist_h = $(HTSPREFIX)htslib/klist.h
+htslib_knetfile_h = $(HTSPREFIX)htslib/knetfile.h
+htslib_kseq_h = $(HTSPREFIX)htslib/kseq.h
+htslib_ksort_h = $(HTSPREFIX)htslib/ksort.h
+htslib_kstring_h = $(HTSPREFIX)htslib/kstring.h
+htslib_regidx_h = $(HTSPREFIX)htslib/regidx.h
+htslib_sam_h = $(HTSPREFIX)htslib/sam.h $(htslib_hts_h)
+htslib_synced_bcf_reader_h = $(HTSPREFIX)htslib/synced_bcf_reader.h $(htslib_hts_h) $(htslib_vcf_h) $(htslib_tbx_h)
+htslib_tbx_h = $(HTSPREFIX)htslib/tbx.h $(htslib_hts_h)
+htslib_vcf_h = $(HTSPREFIX)htslib/vcf.h $(htslib_hts_h) $(htslib_kstring_h) $(htslib_hts_defs_h)
+htslib_vcf_sweep_h = $(HTSPREFIX)htslib/vcf_sweep.h $(htslib_hts_h) $(htslib_vcf_h)
+htslib_vcfutils_h = $(HTSPREFIX)htslib/vcfutils.h $(htslib_vcf_h)
--- /dev/null
+/* The MIT License
+
+ Copyright (C) 2010, 2013 Genome Research Ltd.
+ Copyright (C) 2011 Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+#include <config.h>
+
+#include <math.h>
+#include <stdlib.h>
+#include "htslib/kfunc.h"
+
+/* Log gamma function
+ * \log{\Gamma(z)}
+ * AS245, 2nd algorithm, http://lib.stat.cmu.edu/apstat/245
+ */
+double kf_lgamma(double z)
+{
+ double x = 0;
+ x += 0.1659470187408462e-06 / (z+7);
+ x += 0.9934937113930748e-05 / (z+6);
+ x -= 0.1385710331296526 / (z+5);
+ x += 12.50734324009056 / (z+4);
+ x -= 176.6150291498386 / (z+3);
+ x += 771.3234287757674 / (z+2);
+ x -= 1259.139216722289 / (z+1);
+ x += 676.5203681218835 / z;
+ x += 0.9999999999995183;
+ return log(x) - 5.58106146679532777 - z + (z-0.5) * log(z+6.5);
+}
+
+/* complementary error function
+ * \frac{2}{\sqrt{\pi}} \int_x^{\infty} e^{-t^2} dt
+ * AS66, 2nd algorithm, http://lib.stat.cmu.edu/apstat/66
+ */
+double kf_erfc(double x)
+{
+ const double p0 = 220.2068679123761;
+ const double p1 = 221.2135961699311;
+ const double p2 = 112.0792914978709;
+ const double p3 = 33.912866078383;
+ const double p4 = 6.37396220353165;
+ const double p5 = .7003830644436881;
+ const double p6 = .03526249659989109;
+ const double q0 = 440.4137358247522;
+ const double q1 = 793.8265125199484;
+ const double q2 = 637.3336333788311;
+ const double q3 = 296.5642487796737;
+ const double q4 = 86.78073220294608;
+ const double q5 = 16.06417757920695;
+ const double q6 = 1.755667163182642;
+ const double q7 = .08838834764831844;
+ double expntl, z, p;
+ z = fabs(x) * M_SQRT2;
+ if (z > 37.) return x > 0.? 0. : 2.;
+ expntl = exp(z * z * - .5);
+ if (z < 10. / M_SQRT2) // for small z
+ p = expntl * ((((((p6 * z + p5) * z + p4) * z + p3) * z + p2) * z + p1) * z + p0)
+ / (((((((q7 * z + q6) * z + q5) * z + q4) * z + q3) * z + q2) * z + q1) * z + q0);
+ else p = expntl / 2.506628274631001 / (z + 1. / (z + 2. / (z + 3. / (z + 4. / (z + .65)))));
+ return x > 0.? 2. * p : 2. * (1. - p);
+}
+
+/* The following computes regularized incomplete gamma functions.
+ * Formulas are taken from Wiki, with additional input from Numerical
+ * Recipes in C (for modified Lentz's algorithm) and AS245
+ * (http://lib.stat.cmu.edu/apstat/245).
+ *
+ * A good online calculator is available at:
+ *
+ * http://www.danielsoper.com/statcalc/calc23.aspx
+ *
+ * It calculates upper incomplete gamma function, which equals
+ * kf_gammaq(s,z)*tgamma(s).
+ */
+
+#define KF_GAMMA_EPS 1e-14
+#define KF_TINY 1e-290
+
+// regularized lower incomplete gamma function, by series expansion
+static double _kf_gammap(double s, double z)
+{
+ double sum, x;
+ int k;
+ for (k = 1, sum = x = 1.; k < 100; ++k) {
+ sum += (x *= z / (s + k));
+ if (x / sum < KF_GAMMA_EPS) break;
+ }
+ return exp(s * log(z) - z - kf_lgamma(s + 1.) + log(sum));
+}
+// regularized upper incomplete gamma function, by continued fraction
+static double _kf_gammaq(double s, double z)
+{
+ int j;
+ double C, D, f;
+ f = 1. + z - s; C = f; D = 0.;
+ // Modified Lentz's algorithm for computing continued fraction
+ // See Numerical Recipes in C, 2nd edition, section 5.2
+ for (j = 1; j < 100; ++j) {
+ double a = j * (s - j), b = (j<<1) + 1 + z - s, d;
+ D = b + a * D;
+ if (D < KF_TINY) D = KF_TINY;
+ C = b + a / C;
+ if (C < KF_TINY) C = KF_TINY;
+ D = 1. / D;
+ d = C * D;
+ f *= d;
+ if (fabs(d - 1.) < KF_GAMMA_EPS) break;
+ }
+ return exp(s * log(z) - z - kf_lgamma(s) - log(f));
+}
+
+double kf_gammap(double s, double z)
+{
+ return z <= 1. || z < s? _kf_gammap(s, z) : 1. - _kf_gammaq(s, z);
+}
+
+double kf_gammaq(double s, double z)
+{
+ return z <= 1. || z < s? 1. - _kf_gammap(s, z) : _kf_gammaq(s, z);
+}
+
+/* Regularized incomplete beta function. The method is taken from
+ * Numerical Recipe in C, 2nd edition, section 6.4. The following web
+ * page calculates the incomplete beta function, which equals
+ * kf_betai(a,b,x) * gamma(a) * gamma(b) / gamma(a+b):
+ *
+ * http://www.danielsoper.com/statcalc/calc36.aspx
+ */
+static double kf_betai_aux(double a, double b, double x)
+{
+ double C, D, f;
+ int j;
+ if (x == 0.) return 0.;
+ if (x == 1.) return 1.;
+ f = 1.; C = f; D = 0.;
+ // Modified Lentz's algorithm for computing continued fraction
+ for (j = 1; j < 200; ++j) {
+ double aa, d;
+ int m = j>>1;
+ aa = (j&1)? -(a + m) * (a + b + m) * x / ((a + 2*m) * (a + 2*m + 1))
+ : m * (b - m) * x / ((a + 2*m - 1) * (a + 2*m));
+ D = 1. + aa * D;
+ if (D < KF_TINY) D = KF_TINY;
+ C = 1. + aa / C;
+ if (C < KF_TINY) C = KF_TINY;
+ D = 1. / D;
+ d = C * D;
+ f *= d;
+ if (fabs(d - 1.) < KF_GAMMA_EPS) break;
+ }
+ return exp(kf_lgamma(a+b) - kf_lgamma(a) - kf_lgamma(b) + a * log(x) + b * log(1.-x)) / a / f;
+}
+double kf_betai(double a, double b, double x)
+{
+ return x < (a + 1.) / (a + b + 2.)? kf_betai_aux(a, b, x) : 1. - kf_betai_aux(b, a, 1. - x);
+}
+
+#ifdef KF_MAIN
+#include <stdio.h>
+int main(int argc, char *argv[])
+{
+ double x = 5.5, y = 3;
+ double a, b;
+ printf("erfc(%lg): %lg, %lg\n", x, erfc(x), kf_erfc(x));
+ printf("upper-gamma(%lg,%lg): %lg\n", x, y, kf_gammaq(y, x)*tgamma(y));
+ a = 2; b = 2; x = 0.5;
+ printf("incomplete-beta(%lg,%lg,%lg): %lg\n", a, b, x, kf_betai(a, b, x) / exp(kf_lgamma(a+b) - kf_lgamma(a) - kf_lgamma(b)));
+ return 0;
+}
+#endif
+
+
+// log\binom{n}{k}
+static double lbinom(int n, int k)
+{
+ if (k == 0 || n == k) return 0;
+ return lgamma(n+1) - lgamma(k+1) - lgamma(n-k+1);
+}
+
+// n11 n12 | n1_
+// n21 n22 | n2_
+//-----------+----
+// n_1 n_2 | n
+
+// hypergeometric distribution
+static double hypergeo(int n11, int n1_, int n_1, int n)
+{
+ return exp(lbinom(n1_, n11) + lbinom(n-n1_, n_1-n11) - lbinom(n, n_1));
+}
+
+typedef struct {
+ int n11, n1_, n_1, n;
+ double p;
+} hgacc_t;
+
+// incremental version of hypergenometric distribution
+static double hypergeo_acc(int n11, int n1_, int n_1, int n, hgacc_t *aux)
+{
+ if (n1_ || n_1 || n) {
+ aux->n11 = n11; aux->n1_ = n1_; aux->n_1 = n_1; aux->n = n;
+ } else { // then only n11 changed; the rest fixed
+ if (n11%11 && n11 + aux->n - aux->n1_ - aux->n_1) {
+ if (n11 == aux->n11 + 1) { // incremental
+ aux->p *= (double)(aux->n1_ - aux->n11) / n11
+ * (aux->n_1 - aux->n11) / (n11 + aux->n - aux->n1_ - aux->n_1);
+ aux->n11 = n11;
+ return aux->p;
+ }
+ if (n11 == aux->n11 - 1) { // incremental
+ aux->p *= (double)aux->n11 / (aux->n1_ - n11)
+ * (aux->n11 + aux->n - aux->n1_ - aux->n_1) / (aux->n_1 - n11);
+ aux->n11 = n11;
+ return aux->p;
+ }
+ }
+ aux->n11 = n11;
+ }
+ aux->p = hypergeo(aux->n11, aux->n1_, aux->n_1, aux->n);
+ return aux->p;
+}
+
+double kt_fisher_exact(int n11, int n12, int n21, int n22, double *_left, double *_right, double *two)
+{
+ int i, j, max, min;
+ double p, q, left, right;
+ hgacc_t aux;
+ int n1_, n_1, n;
+
+ n1_ = n11 + n12; n_1 = n11 + n21; n = n11 + n12 + n21 + n22; // calculate n1_, n_1 and n
+ max = (n_1 < n1_) ? n_1 : n1_; // max n11, for right tail
+ min = n1_ + n_1 - n; // not sure why n11-n22 is used instead of min(n_1,n1_)
+ if (min < 0) min = 0; // min n11, for left tail
+ *two = *_left = *_right = 1.;
+ if (min == max) return 1.; // no need to do test
+ q = hypergeo_acc(n11, n1_, n_1, n, &aux); // the probability of the current table
+ // left tail
+ p = hypergeo_acc(min, 0, 0, 0, &aux);
+ for (left = 0., i = min + 1; p < 0.99999999 * q && i<=max; ++i) // loop until underflow
+ left += p, p = hypergeo_acc(i, 0, 0, 0, &aux);
+ --i;
+ if (p < 1.00000001 * q) left += p;
+ else --i;
+ // right tail
+ p = hypergeo_acc(max, 0, 0, 0, &aux);
+ for (right = 0., j = max - 1; p < 0.99999999 * q && j>=0; --j) // loop until underflow
+ right += p, p = hypergeo_acc(j, 0, 0, 0, &aux);
+ ++j;
+ if (p < 1.00000001 * q) right += p;
+ else ++j;
+ // two-tail
+ *two = left + right;
+ if (*two > 1.) *two = 1.;
+ // adjust left and right
+ if (abs(i - n11) < abs(j - n11)) right = 1. - left + q;
+ else left = 1.0 - right + q;
+ *_left = left; *_right = right;
+ return q;
+}
+
+
+
--- /dev/null
+/* The MIT License
+
+ Copyright (c) 2008 by Genome Research Ltd (GRL).
+ 2010 by Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+/* Probably I will not do socket programming in the next few years and
+ therefore I decide to heavily annotate this file, for Linux and
+ Windows as well. -ac */
+
+#include <config.h>
+
+#include <time.h>
+#include <stdio.h>
+#include <ctype.h>
+#include <stdlib.h>
+#include <string.h>
+#include <errno.h>
+#include <unistd.h>
+#include <sys/types.h>
+
+#ifndef _WIN32
+#include <netdb.h>
+#include <arpa/inet.h>
+#include <sys/socket.h>
+#endif
+
+#include "htslib/knetfile.h"
+
+/* In winsock.h, the type of a socket is SOCKET, which is: "typedef
+ * u_int SOCKET". An invalid SOCKET is: "(SOCKET)(~0)", or signed
+ * integer -1. In knetfile.c, I use "int" for socket type
+ * throughout. This should be improved to avoid confusion.
+ *
+ * In Linux/Mac, recv() and read() do almost the same thing. You can see
+ * in the header file that netread() is simply an alias of read(). In
+ * Windows, however, they are different and using recv() is mandatory.
+ */
+
+/* This function tests if the file handler is ready for reading (or
+ * writing if is_read==0). */
+static int socket_wait(int fd, int is_read)
+{
+ fd_set fds, *fdr = 0, *fdw = 0;
+ struct timeval tv;
+ int ret;
+ tv.tv_sec = 5; tv.tv_usec = 0; // 5 seconds time out
+ FD_ZERO(&fds);
+ FD_SET(fd, &fds);
+ if (is_read) fdr = &fds;
+ else fdw = &fds;
+ ret = select(fd+1, fdr, fdw, 0, &tv);
+#ifndef _WIN32
+ if (ret == -1) perror("select");
+#else
+ if (ret == 0)
+ fprintf(stderr, "select time-out\n");
+ else if (ret == SOCKET_ERROR)
+ fprintf(stderr, "select: %d\n", WSAGetLastError());
+#endif
+ return ret;
+}
+
+#ifndef _WIN32
+/* This function does not work with Windows due to the lack of
+ * getaddrinfo() in winsock. It is addapted from an example in "Beej's
+ * Guide to Network Programming" (http://beej.us/guide/bgnet/). */
+static int socket_connect(const char *host, const char *port)
+{
+#define __err_connect(func) do { perror(func); freeaddrinfo(res); return -1; } while (0)
+
+ int ai_err, on = 1, fd;
+ struct linger lng = { 0, 0 };
+ struct addrinfo hints, *res = 0;
+ memset(&hints, 0, sizeof(struct addrinfo));
+ hints.ai_family = AF_UNSPEC;
+ hints.ai_socktype = SOCK_STREAM;
+ /* In Unix/Mac, getaddrinfo() is the most convenient way to get
+ * server information. */
+ if ((ai_err = getaddrinfo(host, port, &hints, &res)) != 0) { fprintf(stderr, "can't resolve %s:%s: %s\n", host, port, gai_strerror(ai_err)); return -1; }
+ if ((fd = socket(res->ai_family, res->ai_socktype, res->ai_protocol)) == -1) __err_connect("socket");
+ /* The following two setsockopt() are used by ftplib
+ * (http://nbpfaus.net/~pfau/ftplib/). I am not sure if they
+ * necessary. */
+ if (setsockopt(fd, SOL_SOCKET, SO_REUSEADDR, &on, sizeof(on)) == -1) __err_connect("setsockopt");
+ if (setsockopt(fd, SOL_SOCKET, SO_LINGER, &lng, sizeof(lng)) == -1) __err_connect("setsockopt");
+ if (connect(fd, res->ai_addr, res->ai_addrlen) != 0) __err_connect("connect");
+ freeaddrinfo(res);
+ return fd;
+}
+#else
+/* MinGW's printf has problem with "%lld" */
+char *int64tostr(char *buf, int64_t x)
+{
+ int cnt;
+ int i = 0;
+ do {
+ buf[i++] = '0' + x % 10;
+ x /= 10;
+ } while (x);
+ buf[i] = 0;
+ for (cnt = i, i = 0; i < cnt/2; ++i) {
+ int c = buf[i]; buf[i] = buf[cnt-i-1]; buf[cnt-i-1] = c;
+ }
+ return buf;
+}
+
+int64_t strtoint64(const char *buf)
+{
+ int64_t x;
+ for (x = 0; *buf != '\0'; ++buf)
+ x = x * 10 + ((int64_t) *buf - 48);
+ return x;
+}
+/* In windows, the first thing is to establish the TCP connection. */
+int knet_win32_init()
+{
+ WSADATA wsaData;
+ return WSAStartup(MAKEWORD(2, 2), &wsaData);
+}
+void knet_win32_destroy()
+{
+ WSACleanup();
+}
+/* A slightly modfied version of the following function also works on
+ * Mac (and presummably Linux). However, this function is not stable on
+ * my Mac. It sometimes works fine but sometimes does not. Therefore for
+ * non-Windows OS, I do not use this one. */
+static SOCKET socket_connect(const char *host, const char *port)
+{
+#define __err_connect(func) \
+ do { \
+ fprintf(stderr, "%s: %d\n", func, WSAGetLastError()); \
+ return -1; \
+ } while (0)
+
+ int on = 1;
+ SOCKET fd;
+ struct linger lng = { 0, 0 };
+ struct sockaddr_in server;
+ struct hostent *hp = 0;
+ // open socket
+ if ((fd = socket(AF_INET, SOCK_STREAM, IPPROTO_TCP)) == INVALID_SOCKET) __err_connect("socket");
+ if (setsockopt(fd, SOL_SOCKET, SO_REUSEADDR, (char*)&on, sizeof(on)) == -1) __err_connect("setsockopt");
+ if (setsockopt(fd, SOL_SOCKET, SO_LINGER, (char*)&lng, sizeof(lng)) == -1) __err_connect("setsockopt");
+ // get host info
+ if (isalpha(host[0])) hp = gethostbyname(host);
+ else {
+ struct in_addr addr;
+ addr.s_addr = inet_addr(host);
+ hp = gethostbyaddr((char*)&addr, 4, AF_INET);
+ }
+ if (hp == 0) __err_connect("gethost");
+ // connect
+ server.sin_addr.s_addr = *((unsigned long*)hp->h_addr);
+ server.sin_family= AF_INET;
+ server.sin_port = htons(atoi(port));
+ if (connect(fd, (struct sockaddr*)&server, sizeof(server)) != 0) __err_connect("connect");
+ // freehostent(hp); // strangely in MSDN, hp is NOT freed (memory leak?!)
+ return fd;
+}
+#endif
+
+static off_t my_netread(int fd, void *buf, off_t len)
+{
+ off_t rest = len, curr, l = 0;
+ /* recv() and read() may not read the required length of data with
+ * one call. They have to be called repeatedly. */
+ while (rest) {
+ if (socket_wait(fd, 1) <= 0) break; // socket is not ready for reading
+ curr = netread(fd, (void*)((char*)buf + l), rest);
+ /* According to the glibc manual, section 13.2, a zero returned
+ * value indicates end-of-file (EOF), which should mean that
+ * read() will not return zero if EOF has not been met but data
+ * are not immediately available. */
+ if (curr == 0) break;
+ l += curr; rest -= curr;
+ }
+ return l;
+}
+
+/*************************
+ * FTP specific routines *
+ *************************/
+
+static int kftp_get_response(knetFile *ftp)
+{
+#ifndef _WIN32
+ unsigned char c;
+#else
+ char c;
+#endif
+ int n = 0;
+ char *p;
+ if (socket_wait(ftp->ctrl_fd, 1) <= 0) return 0;
+ while (netread(ftp->ctrl_fd, &c, 1)) { // FIXME: this is *VERY BAD* for unbuffered I/O
+ //fputc(c, stderr);
+ if (n >= ftp->max_response) {
+ ftp->max_response = ftp->max_response? ftp->max_response<<1 : 256;
+ ftp->response = (char*)realloc(ftp->response, ftp->max_response);
+ }
+ ftp->response[n++] = c;
+ if (c == '\n') {
+ if (n >= 4 && isdigit(ftp->response[0]) && isdigit(ftp->response[1]) && isdigit(ftp->response[2])
+ && ftp->response[3] != '-') break;
+ n = 0;
+ continue;
+ }
+ }
+ if (n < 2) return -1;
+ ftp->response[n-2] = 0;
+ return strtol(ftp->response, &p, 0);
+}
+
+static int kftp_send_cmd(knetFile *ftp, const char *cmd, int is_get)
+{
+ if (socket_wait(ftp->ctrl_fd, 0) <= 0) return -1; // socket is not ready for writing
+ int len = strlen(cmd);
+ if ( netwrite(ftp->ctrl_fd, cmd, len) != len ) return -1;
+ return is_get? kftp_get_response(ftp) : 0;
+}
+
+static int kftp_pasv_prep(knetFile *ftp)
+{
+ char *p;
+ int v[6];
+ kftp_send_cmd(ftp, "PASV\r\n", 1);
+ for (p = ftp->response; *p && *p != '('; ++p);
+ if (*p != '(') return -1;
+ ++p;
+ sscanf(p, "%d,%d,%d,%d,%d,%d", &v[0], &v[1], &v[2], &v[3], &v[4], &v[5]);
+ memcpy(ftp->pasv_ip, v, 4 * sizeof(int));
+ ftp->pasv_port = (v[4]<<8&0xff00) + v[5];
+ return 0;
+}
+
+
+static int kftp_pasv_connect(knetFile *ftp)
+{
+ char host[80], port[10];
+ if (ftp->pasv_port == 0) {
+ fprintf(stderr, "[kftp_pasv_connect] kftp_pasv_prep() is not called before hand.\n");
+ return -1;
+ }
+ sprintf(host, "%d.%d.%d.%d", ftp->pasv_ip[0], ftp->pasv_ip[1], ftp->pasv_ip[2], ftp->pasv_ip[3]);
+ sprintf(port, "%d", ftp->pasv_port);
+ ftp->fd = socket_connect(host, port);
+ if (ftp->fd == -1) return -1;
+ return 0;
+}
+
+int kftp_connect(knetFile *ftp)
+{
+ ftp->ctrl_fd = socket_connect(ftp->host, ftp->port);
+ if (ftp->ctrl_fd == -1) return -1;
+ kftp_get_response(ftp);
+ kftp_send_cmd(ftp, "USER anonymous\r\n", 1);
+ kftp_send_cmd(ftp, "PASS kftp@\r\n", 1);
+ kftp_send_cmd(ftp, "TYPE I\r\n", 1);
+ return 0;
+}
+
+int kftp_reconnect(knetFile *ftp)
+{
+ if (ftp->ctrl_fd != -1) {
+ netclose(ftp->ctrl_fd);
+ ftp->ctrl_fd = -1;
+ }
+ netclose(ftp->fd);
+ ftp->fd = -1;
+ return kftp_connect(ftp);
+}
+
+// initialize ->type, ->host, ->retr and ->size
+knetFile *kftp_parse_url(const char *fn, const char *mode)
+{
+ knetFile *fp;
+ char *p;
+ int l;
+ if (strstr(fn, "ftp://") != fn) return 0;
+ for (p = (char*)fn + 6; *p && *p != '/'; ++p);
+ if (*p != '/') return 0;
+ l = p - fn - 6;
+ fp = (knetFile*)calloc(1, sizeof(knetFile));
+ fp->type = KNF_TYPE_FTP;
+ fp->fd = -1;
+ /* the Linux/Mac version of socket_connect() also recognizes a port
+ * like "ftp", but the Windows version does not. */
+ fp->port = strdup("21");
+ fp->host = (char*)calloc(l + 1, 1);
+ if (strchr(mode, 'c')) fp->no_reconnect = 1;
+ strncpy(fp->host, fn + 6, l);
+ fp->retr = (char*)calloc(strlen(p) + 8, 1);
+ sprintf(fp->retr, "RETR %s\r\n", p);
+ fp->size_cmd = (char*)calloc(strlen(p) + 8, 1);
+ sprintf(fp->size_cmd, "SIZE %s\r\n", p);
+ fp->seek_offset = 0;
+ return fp;
+}
+// place ->fd at offset off
+int kftp_connect_file(knetFile *fp)
+{
+ int ret;
+ long long file_size;
+ if (fp->fd != -1) {
+ netclose(fp->fd);
+ if (fp->no_reconnect) kftp_get_response(fp);
+ }
+ kftp_pasv_prep(fp);
+ kftp_send_cmd(fp, fp->size_cmd, 1);
+#ifndef _WIN32
+ // If the file does not exist, the response will be "550 Could not get file
+ // size". Be silent on failure, hts_idx_load can be trying the existence of .csi or .tbi.
+ if ( sscanf(fp->response,"%*d %lld", &file_size) != 1 ) return -1;
+#else
+ const char *p = fp->response;
+ while (*p != ' ') ++p;
+ while (*p < '0' || *p > '9') ++p;
+ file_size = strtoint64(p);
+#endif
+ fp->file_size = file_size;
+ if (fp->offset>=0) {
+ char tmp[32];
+#ifndef _WIN32
+ sprintf(tmp, "REST %lld\r\n", (long long)fp->offset);
+#else
+ strcpy(tmp, "REST ");
+ int64tostr(tmp + 5, fp->offset);
+ strcat(tmp, "\r\n");
+#endif
+ kftp_send_cmd(fp, tmp, 1);
+ }
+ kftp_send_cmd(fp, fp->retr, 0);
+ kftp_pasv_connect(fp);
+ ret = kftp_get_response(fp);
+ if (ret != 150) {
+ fprintf(stderr, "[kftp_connect_file] %s\n", fp->response);
+ netclose(fp->fd);
+ fp->fd = -1;
+ return -1;
+ }
+ fp->is_ready = 1;
+ return 0;
+}
+
+
+/**************************
+ * HTTP specific routines *
+ **************************/
+
+knetFile *khttp_parse_url(const char *fn, const char *mode)
+{
+ knetFile *fp;
+ char *p, *proxy, *q;
+ int l;
+ if (strstr(fn, "http://") != fn) return 0;
+ // set ->http_host
+ for (p = (char*)fn + 7; *p && *p != '/'; ++p);
+ l = p - fn - 7;
+ fp = (knetFile*)calloc(1, sizeof(knetFile));
+ fp->http_host = (char*)calloc(l + 1, 1);
+ strncpy(fp->http_host, fn + 7, l);
+ fp->http_host[l] = 0;
+ for (q = fp->http_host; *q && *q != ':'; ++q);
+ if (*q == ':') *q++ = 0;
+ // get http_proxy
+ proxy = getenv("http_proxy");
+ // set ->host, ->port and ->path
+ if (proxy == 0) {
+ fp->host = strdup(fp->http_host); // when there is no proxy, server name is identical to http_host name.
+ fp->port = strdup(*q? q : "80");
+ fp->path = strdup(*p? p : "/");
+ } else {
+ fp->host = (strstr(proxy, "http://") == proxy)? strdup(proxy + 7) : strdup(proxy);
+ for (q = fp->host; *q && *q != ':'; ++q);
+ if (*q == ':') *q++ = 0;
+ fp->port = strdup(*q? q : "80");
+ fp->path = strdup(fn);
+ }
+ fp->type = KNF_TYPE_HTTP;
+ fp->ctrl_fd = fp->fd = -1;
+ fp->seek_offset = 0;
+ return fp;
+}
+
+int khttp_connect_file(knetFile *fp)
+{
+ int ret, l = 0;
+ char *buf, *p;
+ if (fp->fd != -1) netclose(fp->fd);
+ fp->fd = socket_connect(fp->host, fp->port);
+ buf = (char*)calloc(0x10000, 1); // FIXME: I am lazy... But in principle, 64KB should be large enough.
+ l += sprintf(buf + l, "GET %s HTTP/1.0\r\nHost: %s\r\n", fp->path, fp->http_host);
+ l += sprintf(buf + l, "Range: bytes=%lld-\r\n", (long long)fp->offset);
+ l += sprintf(buf + l, "\r\n");
+ if ( netwrite(fp->fd, buf, l) != l ) { free(buf); return -1; }
+ l = 0;
+ while (netread(fp->fd, buf + l, 1)) { // read HTTP header; FIXME: bad efficiency
+ if (buf[l] == '\n' && l >= 3)
+ if (strncmp(buf + l - 3, "\r\n\r\n", 4) == 0) break;
+ ++l;
+ }
+ buf[l] = 0;
+ if (l < 14) { // prematured header
+ free(buf);
+ netclose(fp->fd);
+ fp->fd = -1;
+ return -1;
+ }
+ ret = strtol(buf + 8, &p, 0); // HTTP return code
+ if (ret == 200 && fp->offset>0) { // 200 (complete result); then skip beginning of the file
+ off_t rest = fp->offset;
+ while (rest) {
+ off_t l = rest < 0x10000? rest : 0x10000;
+ rest -= my_netread(fp->fd, buf, l);
+ }
+ } else if (ret != 206 && ret != 200) {
+ // failed to open file
+ free(buf);
+ netclose(fp->fd);
+ switch (ret) {
+ case 401: errno = EPERM; break;
+ case 403: errno = EACCES; break;
+ case 404: errno = ENOENT; break;
+ case 407: errno = EPERM; break;
+ case 408: errno = ETIMEDOUT; break;
+ case 410: errno = ENOENT; break;
+ case 503: errno = EAGAIN; break;
+ case 504: errno = ETIMEDOUT; break;
+ default: errno = (ret >= 400 && ret < 500)? EINVAL : EIO; break;
+ }
+ fp->fd = -1;
+ return -1;
+ }
+ free(buf);
+ fp->is_ready = 1;
+ return 0;
+}
+
+/********************
+ * Generic routines *
+ ********************/
+
+knetFile *knet_open(const char *fn, const char *mode)
+{
+ knetFile *fp = 0;
+ if (mode[0] != 'r') {
+ fprintf(stderr, "[kftp_open] only mode \"r\" is supported.\n");
+ return 0;
+ }
+ if (strstr(fn, "ftp://") == fn) {
+ fp = kftp_parse_url(fn, mode);
+ if (fp == 0) return 0;
+ if (kftp_connect(fp) == -1) {
+ knet_close(fp);
+ return 0;
+ }
+ kftp_connect_file(fp);
+ } else if (strstr(fn, "http://") == fn) {
+ fp = khttp_parse_url(fn, mode);
+ if (fp == 0) return 0;
+ khttp_connect_file(fp);
+ } else { // local file
+#ifdef _WIN32
+ /* In windows, O_BINARY is necessary. In Linux/Mac, O_BINARY may
+ * be undefined on some systems, although it is defined on my
+ * Mac and the Linux I have tested on. */
+ int fd = open(fn, O_RDONLY | O_BINARY);
+#else
+ int fd = open(fn, O_RDONLY);
+#endif
+ if (fd == -1) {
+ perror("open");
+ return 0;
+ }
+ fp = (knetFile*)calloc(1, sizeof(knetFile));
+ fp->type = KNF_TYPE_LOCAL;
+ fp->fd = fd;
+ fp->ctrl_fd = -1;
+ }
+ if (fp && fp->fd == -1) {
+ knet_close(fp);
+ return 0;
+ }
+ return fp;
+}
+
+knetFile *knet_dopen(int fd, const char *mode)
+{
+ knetFile *fp = (knetFile*)calloc(1, sizeof(knetFile));
+ fp->type = KNF_TYPE_LOCAL;
+ fp->fd = fd;
+ return fp;
+}
+
+ssize_t knet_read(knetFile *fp, void *buf, size_t len)
+{
+ off_t l = 0;
+ if (fp->fd == -1) return 0;
+ if (fp->type == KNF_TYPE_FTP) {
+ if (fp->is_ready == 0) {
+ if (!fp->no_reconnect) kftp_reconnect(fp);
+ kftp_connect_file(fp);
+ }
+ } else if (fp->type == KNF_TYPE_HTTP) {
+ if (fp->is_ready == 0)
+ khttp_connect_file(fp);
+ }
+ if (fp->type == KNF_TYPE_LOCAL) { // on Windows, the following block is necessary; not on UNIX
+ size_t rest = len;
+ ssize_t curr;
+ while (rest) {
+ do {
+ curr = read(fp->fd, (void*)((char*)buf + l), rest);
+ } while (curr < 0 && EINTR == errno);
+ if (curr < 0) return -1;
+ if (curr == 0) break;
+ l += curr; rest -= curr;
+ }
+ } else l = my_netread(fp->fd, buf, len);
+ fp->offset += l;
+ return l;
+}
+
+off_t knet_seek(knetFile *fp, off_t off, int whence)
+{
+ if (whence == SEEK_SET && off == fp->offset) return 0;
+ if (fp->type == KNF_TYPE_LOCAL) {
+ /* Be aware that lseek() returns the offset after seeking, while fseek() returns zero on success. */
+ off_t offset = lseek(fp->fd, off, whence);
+ if (offset == -1) return -1;
+ fp->offset = offset;
+ return fp->offset;
+ } else if (fp->type == KNF_TYPE_FTP) {
+ if (whence == SEEK_CUR) fp->offset += off;
+ else if (whence == SEEK_SET) fp->offset = off;
+ else if (whence == SEEK_END) fp->offset = fp->file_size + off;
+ else return -1;
+ fp->is_ready = 0;
+ return fp->offset;
+ } else if (fp->type == KNF_TYPE_HTTP) {
+ if (whence == SEEK_END) { // FIXME: can we allow SEEK_END in future?
+ fprintf(stderr, "[knet_seek] SEEK_END is not supported for HTTP. Offset is unchanged.\n");
+ errno = ESPIPE;
+ return -1;
+ }
+ if (whence == SEEK_CUR) fp->offset += off;
+ else if (whence == SEEK_SET) fp->offset = off;
+ else return -1;
+ fp->is_ready = 0;
+ return fp->offset;
+ }
+ errno = EINVAL;
+ fprintf(stderr,"[knet_seek] %s\n", strerror(errno));
+ return -1;
+}
+
+int knet_close(knetFile *fp)
+{
+ if (fp == 0) return 0;
+ if (fp->ctrl_fd != -1) netclose(fp->ctrl_fd); // FTP specific
+ if (fp->fd != -1) {
+ /* On Linux/Mac, netclose() is an alias of close(), but on
+ * Windows, it is an alias of closesocket(). */
+ if (fp->type == KNF_TYPE_LOCAL) close(fp->fd);
+ else netclose(fp->fd);
+ }
+ free(fp->host); free(fp->port);
+ free(fp->response); free(fp->retr); // FTP specific
+ free(fp->path); free(fp->http_host); // HTTP specific
+ free(fp);
+ return 0;
+}
+
+#ifdef KNETFILE_MAIN
+int main(void)
+{
+ char *buf;
+ knetFile *fp;
+ int type = 4, l;
+#ifdef _WIN32
+ knet_win32_init();
+#endif
+ buf = calloc(0x100000, 1);
+ if (type == 0) {
+ fp = knet_open("knetfile.c", "r");
+ knet_seek(fp, 1000, SEEK_SET);
+ } else if (type == 1) { // NCBI FTP, large file
+ fp = knet_open("ftp://ftp.ncbi.nih.gov/1000genomes/ftp/data/NA12878/alignment/NA12878.chrom6.SLX.SRP000032.2009_06.bam", "r");
+ knet_seek(fp, 2500000000ll, SEEK_SET);
+ l = knet_read(fp, buf, 255);
+ } else if (type == 2) {
+ fp = knet_open("ftp://ftp.sanger.ac.uk/pub4/treefam/tmp/index.shtml", "r");
+ knet_seek(fp, 1000, SEEK_SET);
+ } else if (type == 3) {
+ fp = knet_open("http://www.sanger.ac.uk/Users/lh3/index.shtml", "r");
+ knet_seek(fp, 1000, SEEK_SET);
+ } else if (type == 4) {
+ fp = knet_open("http://www.sanger.ac.uk/Users/lh3/ex1.bam", "r");
+ knet_read(fp, buf, 10000);
+ knet_seek(fp, 20000, SEEK_SET);
+ knet_seek(fp, 10000, SEEK_SET);
+ l = knet_read(fp, buf+10000, 10000000) + 10000;
+ }
+ if (type != 4 && type != 1) {
+ knet_read(fp, buf, 255);
+ buf[255] = 0;
+ printf("%s\n", buf);
+ } else write(fileno(stdout), buf, l);
+ knet_close(fp);
+ free(buf);
+ return 0;
+}
+#endif
--- /dev/null
+/* The MIT License
+
+ Copyright (C) 2011 by Attractive Chaos <attractor@live.co.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining
+ a copy of this software and associated documentation files (the
+ "Software"), to deal in the Software without restriction, including
+ without limitation the rights to use, copy, modify, merge, publish,
+ distribute, sublicense, and/or sell copies of the Software, and to
+ permit persons to whom the Software is furnished to do so, subject to
+ the following conditions:
+
+ The above copyright notice and this permission notice shall be
+ included in all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND,
+ EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF
+ MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
+ NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS
+ BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN
+ ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN
+ CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+ SOFTWARE.
+*/
+
+#include <config.h>
+
+#include <stdarg.h>
+#include <stdio.h>
+#include <ctype.h>
+#include <string.h>
+#include <stdint.h>
+#include "htslib/kstring.h"
+
+int kvsprintf(kstring_t *s, const char *fmt, va_list ap)
+{
+ va_list args;
+ int l;
+ va_copy(args, ap);
+ l = vsnprintf(s->s + s->l, s->m - s->l, fmt, args); // This line does not work with glibc 2.0. See `man snprintf'.
+ va_end(args);
+ if (l + 1 > s->m - s->l) {
+ s->m = s->l + l + 2;
+ kroundup32(s->m);
+ s->s = (char*)realloc(s->s, s->m);
+ va_copy(args, ap);
+ l = vsnprintf(s->s + s->l, s->m - s->l, fmt, args);
+ va_end(args);
+ }
+ s->l += l;
+ return l;
+}
+
+int ksprintf(kstring_t *s, const char *fmt, ...)
+{
+ va_list ap;
+ int l;
+ va_start(ap, fmt);
+ l = kvsprintf(s, fmt, ap);
+ va_end(ap);
+ return l;
+}
+
+char *kstrtok(const char *str, const char *sep, ks_tokaux_t *aux)
+{
+ const char *p, *start;
+ if (sep) { // set up the table
+ if (str == 0 && (aux->tab[0]&1)) return 0; // no need to set up if we have finished
+ aux->finished = 0;
+ if (sep[1]) {
+ aux->sep = -1;
+ aux->tab[0] = aux->tab[1] = aux->tab[2] = aux->tab[3] = 0;
+ for (p = sep; *p; ++p) aux->tab[*p>>6] |= 1ull<<(*p&0x3f);
+ } else aux->sep = sep[0];
+ }
+ if (aux->finished) return 0;
+ else if (str) aux->p = str - 1, aux->finished = 0;
+ if (aux->sep < 0) {
+ for (p = start = aux->p + 1; *p; ++p)
+ if (aux->tab[*p>>6]>>(*p&0x3f)&1) break;
+ } else {
+ for (p = start = aux->p + 1; *p; ++p)
+ if (*p == aux->sep) break;
+ }
+ aux->p = p; // end of token
+ if (*p == 0) aux->finished = 1; // no more tokens
+ return (char*)start;
+}
+
+// s MUST BE a null terminated string; l = strlen(s)
+int ksplit_core(char *s, int delimiter, int *_max, int **_offsets)
+{
+ int i, n, max, last_char, last_start, *offsets, l;
+ n = 0; max = *_max; offsets = *_offsets;
+ l = strlen(s);
+
+#define __ksplit_aux do { \
+ if (_offsets) { \
+ s[i] = 0; \
+ if (n == max) { \
+ int *tmp; \
+ max = max? max<<1 : 2; \
+ if ((tmp = (int*)realloc(offsets, sizeof(int) * max))) { \
+ offsets = tmp; \
+ } else { \
+ free(offsets); \
+ *_offsets = NULL; \
+ return 0; \
+ } \
+ } \
+ offsets[n++] = last_start; \
+ } else ++n; \
+ } while (0)
+
+ for (i = 0, last_char = last_start = 0; i <= l; ++i) {
+ if (delimiter == 0) {
+ if (isspace(s[i]) || s[i] == 0) {
+ if (isgraph(last_char)) __ksplit_aux; // the end of a field
+ } else {
+ if (isspace(last_char) || last_char == 0) last_start = i;
+ }
+ } else {
+ if (s[i] == delimiter || s[i] == 0) {
+ if (last_char != 0 && last_char != delimiter) __ksplit_aux; // the end of a field
+ } else {
+ if (last_char == delimiter || last_char == 0) last_start = i;
+ }
+ }
+ last_char = s[i];
+ }
+ *_max = max; *_offsets = offsets;
+ return n;
+}
+
+int kgetline(kstring_t *s, kgets_func *fgets_fn, void *fp)
+{
+ size_t l0 = s->l;
+
+ while (s->l == l0 || s->s[s->l-1] != '\n') {
+ if (s->m - s->l < 200) ks_resize(s, s->m + 200);
+ if (fgets_fn(s->s + s->l, s->m - s->l, fp) == NULL) break;
+ s->l += strlen(s->s + s->l);
+ }
+
+ if (s->l == l0) return EOF;
+
+ if (s->l > l0 && s->s[s->l-1] == '\n') {
+ s->l--;
+ if (s->l > l0 && s->s[s->l-1] == '\r') s->l--;
+ }
+ s->s[s->l] = '\0';
+ return 0;
+}
+
+/**********************
+ * Boyer-Moore search *
+ **********************/
+
+typedef unsigned char ubyte_t;
+
+// reference: http://www-igm.univ-mlv.fr/~lecroq/string/node14.html
+static int *ksBM_prep(const ubyte_t *pat, int m)
+{
+ int i, *suff, *prep, *bmGs, *bmBc;
+ prep = (int*)calloc(m + 256, sizeof(int));
+ bmGs = prep; bmBc = prep + m;
+ { // preBmBc()
+ for (i = 0; i < 256; ++i) bmBc[i] = m;
+ for (i = 0; i < m - 1; ++i) bmBc[pat[i]] = m - i - 1;
+ }
+ suff = (int*)calloc(m, sizeof(int));
+ { // suffixes()
+ int f = 0, g;
+ suff[m - 1] = m;
+ g = m - 1;
+ for (i = m - 2; i >= 0; --i) {
+ if (i > g && suff[i + m - 1 - f] < i - g)
+ suff[i] = suff[i + m - 1 - f];
+ else {
+ if (i < g) g = i;
+ f = i;
+ while (g >= 0 && pat[g] == pat[g + m - 1 - f]) --g;
+ suff[i] = f - g;
+ }
+ }
+ }
+ { // preBmGs()
+ int j = 0;
+ for (i = 0; i < m; ++i) bmGs[i] = m;
+ for (i = m - 1; i >= 0; --i)
+ if (suff[i] == i + 1)
+ for (; j < m - 1 - i; ++j)
+ if (bmGs[j] == m)
+ bmGs[j] = m - 1 - i;
+ for (i = 0; i <= m - 2; ++i)
+ bmGs[m - 1 - suff[i]] = m - 1 - i;
+ }
+ free(suff);
+ return prep;
+}
+
+void *kmemmem(const void *_str, int n, const void *_pat, int m, int **_prep)
+{
+ int i, j, *prep = 0, *bmGs, *bmBc;
+ const ubyte_t *str, *pat;
+ str = (const ubyte_t*)_str; pat = (const ubyte_t*)_pat;
+ prep = (_prep == 0 || *_prep == 0)? ksBM_prep(pat, m) : *_prep;
+ if (_prep && *_prep == 0) *_prep = prep;
+ bmGs = prep; bmBc = prep + m;
+ j = 0;
+ while (j <= n - m) {
+ for (i = m - 1; i >= 0 && pat[i] == str[i+j]; --i);
+ if (i >= 0) {
+ int max = bmBc[str[i+j]] - m + 1 + i;
+ if (max < bmGs[i]) max = bmGs[i];
+ j += max;
+ } else return (void*)(str + j);
+ }
+ if (_prep == 0) free(prep);
+ return 0;
+}
+
+char *kstrstr(const char *str, const char *pat, int **_prep)
+{
+ return (char*)kmemmem(str, strlen(str), pat, strlen(pat), _prep);
+}
+
+char *kstrnstr(const char *str, const char *pat, int n, int **_prep)
+{
+ return (char*)kmemmem(str, n, pat, strlen(pat), _prep);
+}
+
+/***********************
+ * The main() function *
+ ***********************/
+
+#ifdef KSTRING_MAIN
+#include <stdio.h>
+int main()
+{
+ kstring_t *s;
+ int *fields, n, i;
+ ks_tokaux_t aux;
+ char *p;
+ s = (kstring_t*)calloc(1, sizeof(kstring_t));
+ // test ksprintf()
+ ksprintf(s, " abcdefg: %d ", 100);
+ printf("'%s'\n", s->s);
+ // test ksplit()
+ fields = ksplit(s, 0, &n);
+ for (i = 0; i < n; ++i)
+ printf("field[%d] = '%s'\n", i, s->s + fields[i]);
+ // test kstrtok()
+ s->l = 0;
+ for (p = kstrtok("ab:cde:fg/hij::k", ":/", &aux); p; p = kstrtok(0, 0, &aux)) {
+ kputsn(p, aux.p - p, s);
+ kputc('\n', s);
+ }
+ printf("%s", s->s);
+ // free
+ free(s->s); free(s); free(fields);
+
+ {
+ static char *str = "abcdefgcdgcagtcakcdcd";
+ static char *pat = "cd";
+ char *ret, *s = str;
+ int *prep = 0;
+ while ((ret = kstrstr(s, pat, &prep)) != 0) {
+ printf("match: %s\n", ret);
+ s = ret + prep[0];
+ }
+ free(prep);
+ }
+ return 0;
+}
+#endif
--- /dev/null
+/*
+ * Trivial amendments by James Bonfield <jkb@sanger.ac.uk> to provide an
+ * HTSlib interface. 2015.
+ *
+ * Externally our API uses an opaque hts_md5_context structure.
+ *
+ * Internally either this gets defined and used with the routines here
+ * or it remains incomplete and is cast to the OpenSSL MD5_CTX structure
+ * and used by routines from OpenSSL.
+ */
+
+/*
+ * This is an OpenSSL-compatible implementation of the RSA Data Security, Inc.
+ * MD5 Message-Digest Algorithm (RFC 1321).
+ *
+ * Homepage:
+ * http://openwall.info/wiki/people/solar/software/public-domain-source-code/md5
+ *
+ * Author:
+ * Alexander Peslyak, better known as Solar Designer <solar at openwall.com>
+ *
+ * This software was written by Alexander Peslyak in 2001. No copyright is
+ * claimed, and the software is hereby placed in the public domain.
+ * In case this attempt to disclaim copyright and place the software in the
+ * public domain is deemed null and void, then the software is
+ * Copyright (c) 2001 Alexander Peslyak and it is hereby released to the
+ * general public under the following terms:
+ *
+ * Redistribution and use in source and binary forms, with or without
+ * modification, are permitted.
+ *
+ * There's ABSOLUTELY NO WARRANTY, express or implied.
+ *
+ * (This is a heavily cut-down "BSD license".)
+ *
+ * This differs from Colin Plumb's older public domain implementation in that
+ * no exactly 32-bit integer data type is required (any 32-bit or wider
+ * unsigned integer data type will do), there's no compile-time endianness
+ * configuration, and the function prototypes match OpenSSL's. No code from
+ * Colin Plumb's implementation has been reused; this comment merely compares
+ * the properties of the two independent implementations.
+ *
+ * The primary goals of this implementation are portability and ease of use.
+ * It is meant to be fast, but not as fast as possible. Some known
+ * optimizations are not included to reduce source code size and avoid
+ * compile-time configuration.
+ */
+
+#include <config.h>
+
+#include <stdlib.h>
+#include "htslib/hts.h"
+
+#ifndef HAVE_OPENSSL
+
+#include <string.h>
+
+/* Any 32-bit or wider unsigned integer data type will do */
+typedef unsigned int hts_md5_u32plus;
+
+struct hts_md5_context {
+ hts_md5_u32plus lo, hi;
+ hts_md5_u32plus a, b, c, d;
+ unsigned char buffer[64];
+ hts_md5_u32plus block[16];
+};
+
+/*
+ * The basic MD5 functions.
+ *
+ * F and G are optimized compared to their RFC 1321 definitions for
+ * architectures that lack an AND-NOT instruction, just like in Colin Plumb's
+ * implementation.
+ */
+#define F(x, y, z) ((z) ^ ((x) & ((y) ^ (z))))
+#define G(x, y, z) ((y) ^ ((z) & ((x) ^ (y))))
+#define H(x, y, z) (((x) ^ (y)) ^ (z))
+#define H2(x, y, z) ((x) ^ ((y) ^ (z)))
+#define I(x, y, z) ((y) ^ ((x) | ~(z)))
+
+/*
+ * The MD5 transformation for all four rounds.
+ */
+#define STEP(f, a, b, c, d, x, t, s) \
+ (a) += f((b), (c), (d)) + (x) + (t); \
+ (a) = (((a) << (s)) | (((a) & 0xffffffff) >> (32 - (s)))); \
+ (a) += (b);
+
+/*
+ * SET reads 4 input bytes in little-endian byte order and stores them
+ * in a properly aligned word in host byte order.
+ *
+ * The check for little-endian architectures that tolerate unaligned
+ * memory accesses is just an optimization. Nothing will break if it
+ * doesn't work.
+ */
+#if defined(__i386__) || defined(__x86_64__) || defined(__vax__)
+#define SET(n) \
+ (*(hts_md5_u32plus *)&ptr[(n) * 4])
+#define GET(n) \
+ SET(n)
+#else
+#define SET(n) \
+ (ctx->block[(n)] = \
+ (hts_md5_u32plus)ptr[(n) * 4] | \
+ ((hts_md5_u32plus)ptr[(n) * 4 + 1] << 8) | \
+ ((hts_md5_u32plus)ptr[(n) * 4 + 2] << 16) | \
+ ((hts_md5_u32plus)ptr[(n) * 4 + 3] << 24))
+#define GET(n) \
+ (ctx->block[(n)])
+#endif
+
+/*
+ * This processes one or more 64-byte data blocks, but does NOT update
+ * the bit counters. There are no alignment requirements.
+ */
+static const void *body(hts_md5_context *ctx, const void *data, unsigned long size)
+{
+ const unsigned char *ptr;
+ hts_md5_u32plus a, b, c, d;
+ hts_md5_u32plus saved_a, saved_b, saved_c, saved_d;
+
+ ptr = (const unsigned char *)data;
+
+ a = ctx->a;
+ b = ctx->b;
+ c = ctx->c;
+ d = ctx->d;
+
+ do {
+ saved_a = a;
+ saved_b = b;
+ saved_c = c;
+ saved_d = d;
+
+/* Round 1 */
+ STEP(F, a, b, c, d, SET(0), 0xd76aa478, 7)
+ STEP(F, d, a, b, c, SET(1), 0xe8c7b756, 12)
+ STEP(F, c, d, a, b, SET(2), 0x242070db, 17)
+ STEP(F, b, c, d, a, SET(3), 0xc1bdceee, 22)
+ STEP(F, a, b, c, d, SET(4), 0xf57c0faf, 7)
+ STEP(F, d, a, b, c, SET(5), 0x4787c62a, 12)
+ STEP(F, c, d, a, b, SET(6), 0xa8304613, 17)
+ STEP(F, b, c, d, a, SET(7), 0xfd469501, 22)
+ STEP(F, a, b, c, d, SET(8), 0x698098d8, 7)
+ STEP(F, d, a, b, c, SET(9), 0x8b44f7af, 12)
+ STEP(F, c, d, a, b, SET(10), 0xffff5bb1, 17)
+ STEP(F, b, c, d, a, SET(11), 0x895cd7be, 22)
+ STEP(F, a, b, c, d, SET(12), 0x6b901122, 7)
+ STEP(F, d, a, b, c, SET(13), 0xfd987193, 12)
+ STEP(F, c, d, a, b, SET(14), 0xa679438e, 17)
+ STEP(F, b, c, d, a, SET(15), 0x49b40821, 22)
+
+/* Round 2 */
+ STEP(G, a, b, c, d, GET(1), 0xf61e2562, 5)
+ STEP(G, d, a, b, c, GET(6), 0xc040b340, 9)
+ STEP(G, c, d, a, b, GET(11), 0x265e5a51, 14)
+ STEP(G, b, c, d, a, GET(0), 0xe9b6c7aa, 20)
+ STEP(G, a, b, c, d, GET(5), 0xd62f105d, 5)
+ STEP(G, d, a, b, c, GET(10), 0x02441453, 9)
+ STEP(G, c, d, a, b, GET(15), 0xd8a1e681, 14)
+ STEP(G, b, c, d, a, GET(4), 0xe7d3fbc8, 20)
+ STEP(G, a, b, c, d, GET(9), 0x21e1cde6, 5)
+ STEP(G, d, a, b, c, GET(14), 0xc33707d6, 9)
+ STEP(G, c, d, a, b, GET(3), 0xf4d50d87, 14)
+ STEP(G, b, c, d, a, GET(8), 0x455a14ed, 20)
+ STEP(G, a, b, c, d, GET(13), 0xa9e3e905, 5)
+ STEP(G, d, a, b, c, GET(2), 0xfcefa3f8, 9)
+ STEP(G, c, d, a, b, GET(7), 0x676f02d9, 14)
+ STEP(G, b, c, d, a, GET(12), 0x8d2a4c8a, 20)
+
+/* Round 3 */
+ STEP(H, a, b, c, d, GET(5), 0xfffa3942, 4)
+ STEP(H2, d, a, b, c, GET(8), 0x8771f681, 11)
+ STEP(H, c, d, a, b, GET(11), 0x6d9d6122, 16)
+ STEP(H2, b, c, d, a, GET(14), 0xfde5380c, 23)
+ STEP(H, a, b, c, d, GET(1), 0xa4beea44, 4)
+ STEP(H2, d, a, b, c, GET(4), 0x4bdecfa9, 11)
+ STEP(H, c, d, a, b, GET(7), 0xf6bb4b60, 16)
+ STEP(H2, b, c, d, a, GET(10), 0xbebfbc70, 23)
+ STEP(H, a, b, c, d, GET(13), 0x289b7ec6, 4)
+ STEP(H2, d, a, b, c, GET(0), 0xeaa127fa, 11)
+ STEP(H, c, d, a, b, GET(3), 0xd4ef3085, 16)
+ STEP(H2, b, c, d, a, GET(6), 0x04881d05, 23)
+ STEP(H, a, b, c, d, GET(9), 0xd9d4d039, 4)
+ STEP(H2, d, a, b, c, GET(12), 0xe6db99e5, 11)
+ STEP(H, c, d, a, b, GET(15), 0x1fa27cf8, 16)
+ STEP(H2, b, c, d, a, GET(2), 0xc4ac5665, 23)
+
+/* Round 4 */
+ STEP(I, a, b, c, d, GET(0), 0xf4292244, 6)
+ STEP(I, d, a, b, c, GET(7), 0x432aff97, 10)
+ STEP(I, c, d, a, b, GET(14), 0xab9423a7, 15)
+ STEP(I, b, c, d, a, GET(5), 0xfc93a039, 21)
+ STEP(I, a, b, c, d, GET(12), 0x655b59c3, 6)
+ STEP(I, d, a, b, c, GET(3), 0x8f0ccc92, 10)
+ STEP(I, c, d, a, b, GET(10), 0xffeff47d, 15)
+ STEP(I, b, c, d, a, GET(1), 0x85845dd1, 21)
+ STEP(I, a, b, c, d, GET(8), 0x6fa87e4f, 6)
+ STEP(I, d, a, b, c, GET(15), 0xfe2ce6e0, 10)
+ STEP(I, c, d, a, b, GET(6), 0xa3014314, 15)
+ STEP(I, b, c, d, a, GET(13), 0x4e0811a1, 21)
+ STEP(I, a, b, c, d, GET(4), 0xf7537e82, 6)
+ STEP(I, d, a, b, c, GET(11), 0xbd3af235, 10)
+ STEP(I, c, d, a, b, GET(2), 0x2ad7d2bb, 15)
+ STEP(I, b, c, d, a, GET(9), 0xeb86d391, 21)
+
+ a += saved_a;
+ b += saved_b;
+ c += saved_c;
+ d += saved_d;
+
+ ptr += 64;
+ } while (size -= 64);
+
+ ctx->a = a;
+ ctx->b = b;
+ ctx->c = c;
+ ctx->d = d;
+
+ return ptr;
+}
+
+void hts_md5_reset(hts_md5_context *ctx)
+{
+ ctx->a = 0x67452301;
+ ctx->b = 0xefcdab89;
+ ctx->c = 0x98badcfe;
+ ctx->d = 0x10325476;
+
+ ctx->lo = 0;
+ ctx->hi = 0;
+}
+
+void hts_md5_update(hts_md5_context *ctx, const void *data, unsigned long size)
+{
+ hts_md5_u32plus saved_lo;
+ unsigned long used, available;
+
+ saved_lo = ctx->lo;
+ if ((ctx->lo = (saved_lo + size) & 0x1fffffff) < saved_lo)
+ ctx->hi++;
+ ctx->hi += size >> 29;
+
+ used = saved_lo & 0x3f;
+
+ if (used) {
+ available = 64 - used;
+
+ if (size < available) {
+ memcpy(&ctx->buffer[used], data, size);
+ return;
+ }
+
+ memcpy(&ctx->buffer[used], data, available);
+ data = (const unsigned char *)data + available;
+ size -= available;
+ body(ctx, ctx->buffer, 64);
+ }
+
+ if (size >= 64) {
+ data = body(ctx, data, size & ~(unsigned long)0x3f);
+ size &= 0x3f;
+ }
+
+ memcpy(ctx->buffer, data, size);
+}
+
+void hts_md5_final(unsigned char *result, hts_md5_context *ctx)
+{
+ unsigned long used, available;
+
+ used = ctx->lo & 0x3f;
+
+ ctx->buffer[used++] = 0x80;
+
+ available = 64 - used;
+
+ if (available < 8) {
+ memset(&ctx->buffer[used], 0, available);
+ body(ctx, ctx->buffer, 64);
+ used = 0;
+ available = 64;
+ }
+
+ memset(&ctx->buffer[used], 0, available - 8);
+
+ ctx->lo <<= 3;
+ ctx->buffer[56] = ctx->lo;
+ ctx->buffer[57] = ctx->lo >> 8;
+ ctx->buffer[58] = ctx->lo >> 16;
+ ctx->buffer[59] = ctx->lo >> 24;
+ ctx->buffer[60] = ctx->hi;
+ ctx->buffer[61] = ctx->hi >> 8;
+ ctx->buffer[62] = ctx->hi >> 16;
+ ctx->buffer[63] = ctx->hi >> 24;
+
+ body(ctx, ctx->buffer, 64);
+
+ result[0] = ctx->a;
+ result[1] = ctx->a >> 8;
+ result[2] = ctx->a >> 16;
+ result[3] = ctx->a >> 24;
+ result[4] = ctx->b;
+ result[5] = ctx->b >> 8;
+ result[6] = ctx->b >> 16;
+ result[7] = ctx->b >> 24;
+ result[8] = ctx->c;
+ result[9] = ctx->c >> 8;
+ result[10] = ctx->c >> 16;
+ result[11] = ctx->c >> 24;
+ result[12] = ctx->d;
+ result[13] = ctx->d >> 8;
+ result[14] = ctx->d >> 16;
+ result[15] = ctx->d >> 24;
+
+ memset(ctx, 0, sizeof(*ctx));
+}
+
+
+hts_md5_context *hts_md5_init(void)
+{
+ hts_md5_context *ctx = malloc(sizeof(*ctx));
+ if (!ctx)
+ return NULL;
+
+ hts_md5_reset(ctx);
+ return ctx;
+}
+
+#else
+
+#include <openssl/md5.h>
+#include <assert.h>
+
+/*
+ * Wrappers around the OpenSSL libcrypto.so MD5 implementation.
+ *
+ * These are here to ensure they end up in the symbol table of the
+ * library regardless of the static inline in the headers.
+ */
+hts_md5_context *hts_md5_init(void)
+{
+ MD5_CTX *ctx = malloc(sizeof(*ctx));
+ if (!ctx)
+ return NULL;
+
+ MD5_Init(ctx);
+
+ return (hts_md5_context *)ctx;
+}
+
+void hts_md5_reset(hts_md5_context *ctx)
+{
+ MD5_Init((MD5_CTX *)ctx);
+}
+
+void hts_md5_update(hts_md5_context *ctx, const void *data, unsigned long size)
+{
+ MD5_Update((MD5_CTX *)ctx, data, size);
+}
+
+void hts_md5_final(unsigned char *result, hts_md5_context *ctx)
+{
+ MD5_Final(result, (MD5_CTX *)ctx);
+}
+
+#endif
+
+void hts_md5_destroy(hts_md5_context *ctx)
+{
+ if (!ctx)
+ return;
+
+ free(ctx);
+}
+
+void hts_md5_hex(char *hex, const unsigned char *digest)
+{
+ int i;
+ for (i = 0; i < 16; i++) {
+ hex[i*2+0] = "0123456789abcdef"[(digest[i]>>4)&0xf];
+ hex[i*2+1] = "0123456789abcdef"[digest[i]&0xf];
+ }
+ hex[32] = 0;
+}
--- /dev/null
+/* plugin.c -- low-level path parsing and plugin functions.
+
+ Copyright (C) 2015 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <stdlib.h>
+#include <string.h>
+#include <errno.h>
+
+#include <dirent.h>
+#include <dlfcn.h>
+
+#include "hts_internal.h"
+#include "htslib/kstring.h"
+
+#ifndef PLUGINPATH
+#define PLUGINPATH ""
+#endif
+
+#ifdef __APPLE__
+#define PLUGIN_EXT ".bundle"
+#define PLUGIN_EXT_LEN 7
+#else
+#define PLUGIN_EXT ".so"
+#define PLUGIN_EXT_LEN 3
+#endif
+
+static DIR *open_nextdir(struct hts_path_itr *itr)
+{
+ DIR *dir;
+
+ while (1) {
+ const char *colon = strchr(itr->pathdir, ':');
+ if (colon == NULL) return NULL;
+
+ itr->entry.l = 0;
+ kputsn(itr->pathdir, colon - itr->pathdir, &itr->entry);
+ itr->pathdir = &colon[1];
+ if (itr->entry.l == 0) continue;
+
+ dir = opendir(itr->entry.s);
+ if (dir) break;
+
+ if (hts_verbose >= 4)
+ fprintf(stderr,
+ "[W::hts_path_itr] can't scan directory \"%s\": %s\n",
+ itr->entry.s, strerror(errno));
+ }
+
+ if (itr->entry.s[itr->entry.l-1] != '/') kputc('/', &itr->entry);
+ itr->entry_dir_l = itr->entry.l;
+ return dir;
+}
+
+void hts_path_itr_setup(struct hts_path_itr *itr, const char *path,
+ const char *builtin_path, const char *prefix, size_t prefix_len,
+ const char *suffix, size_t suffix_len)
+{
+ itr->prefix = prefix;
+ itr->prefix_len = prefix_len;
+
+ if (suffix) itr->suffix = suffix, itr->suffix_len = suffix_len;
+ else itr->suffix = PLUGIN_EXT, itr->suffix_len = PLUGIN_EXT_LEN;
+
+ itr->path.l = itr->path.m = 0; itr->path.s = NULL;
+ itr->entry.l = itr->entry.m = 0; itr->entry.s = NULL;
+
+ if (! builtin_path) builtin_path = PLUGINPATH;
+ if (! path) {
+ path = getenv("HTS_PATH");
+ if (! path) path = "";
+ }
+
+ while (1) {
+ size_t len = strcspn(path, ":");
+ if (len == 0) kputs(builtin_path, &itr->path);
+ else kputsn(path, len, &itr->path);
+ kputc(':', &itr->path);
+
+ path += len;
+ if (*path == ':') path++;
+ else break;
+ }
+
+ // Note that ':' now terminates entries rather than separates them
+ itr->pathdir = itr->path.s;
+ itr->dirv = open_nextdir(itr);
+}
+
+const char *hts_path_itr_next(struct hts_path_itr *itr)
+{
+ while (itr->dirv) {
+ struct dirent *e;
+ while ((e = readdir((DIR *) itr->dirv)) != NULL) {
+ size_t d_name_len = strlen(e->d_name);
+ if (strncmp(e->d_name, itr->prefix, itr->prefix_len) == 0 &&
+ d_name_len >= itr->suffix_len &&
+ strncmp(e->d_name + d_name_len - itr->suffix_len, itr->suffix,
+ itr->suffix_len) == 0) {
+ itr->entry.l = itr->entry_dir_l;
+ kputs(e->d_name, &itr->entry);
+ return itr->entry.s;
+ }
+ }
+
+ closedir((DIR *) itr->dirv);
+ itr->dirv = open_nextdir(itr);
+ }
+
+ itr->pathdir = NULL;
+ free(itr->path.s); itr->path.s = NULL;
+ free(itr->entry.s); itr->entry.s = NULL;
+ return NULL;
+}
+
+void *load_plugin(void **pluginp, const char *filename, const char *symbol)
+{
+ void *lib = dlopen(filename, RTLD_NOW | RTLD_LOCAL);
+ if (lib == NULL) goto error;
+
+ void *sym = dlsym(lib, symbol);
+ if (sym == NULL) goto error;
+
+ *pluginp = lib;
+ return sym;
+
+error:
+ if (hts_verbose >= 4)
+ fprintf(stderr, "[W::%s] can't load plugin \"%s\": %s\n",
+ __func__, filename, dlerror());
+ if (lib) dlclose(lib);
+ return NULL;
+}
+
+void *plugin_sym(void *plugin, const char *name, const char **errmsg)
+{
+ void *sym = dlsym(plugin, name);
+ if (sym == NULL) *errmsg = dlerror();
+ return sym;
+}
+
+void close_plugin(void *plugin)
+{
+ if (dlclose(plugin) != 0) {
+ if (hts_verbose >= 4)
+ fprintf(stderr, "[W::%s] dlclose() failed: %s\n",
+ __func__, dlerror());
+ }
+}
--- /dev/null
+/*
+ Copyright (C) 2014 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining a copy
+ of this software and associated documentation files (the "Software"), to deal
+ in the Software without restriction, including without limitation the rights
+ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+ copies of the Software, and to permit persons to whom the Software is
+ furnished to do so, subject to the following conditions:
+
+ The above copyright notice and this permission notice shall be included in
+ all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+ IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+ FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+ AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+ LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+ OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
+ THE SOFTWARE.
+*/
+
+#include <config.h>
+
+#include "htslib/hts.h"
+#include "htslib/kstring.h"
+#include "htslib/kseq.h"
+#include "htslib/khash_str2int.h"
+#include "htslib/regidx.h"
+
+#define LIDX_SHIFT 13 // number of insignificant index bits
+
+// List of regions for one chromosome
+typedef struct
+{
+ int *idx, nidx;
+ int nregs, mregs; // n:used, m:alloced
+ reg_t *regs;
+ void *payload;
+}
+reglist_t;
+
+// Container of all sequences
+struct _regidx_t
+{
+ int nseq, mseq; // n:used, m:alloced
+ reglist_t *seq; // regions for each sequence
+ void *seq2regs; // hash for fast lookup from chr name to regions
+ char **seq_names;
+ regidx_free_f free; // function to free any data allocated by regidx_parse_f
+ regidx_parse_f parse; // parse one input line
+ void *usr; // user data to pass to regidx_parse_f
+
+ // temporary data for index initialization
+ kstring_t str;
+ int rid_prev, start_prev, end_prev;
+ int payload_size;
+ void *payload;
+};
+
+int regidx_seq_nregs(regidx_t *idx, const char *seq)
+{
+ int iseq;
+ if ( khash_str2int_get(idx->seq2regs, seq, &iseq)!=0 ) return 0; // no such sequence
+ return idx->seq[iseq].nregs;
+}
+
+int regidx_nregs(regidx_t *idx)
+{
+ int i, nregs = 0;
+ for (i=0; i<idx->nseq; i++) nregs += idx->seq[i].nregs;
+ return nregs;
+}
+
+char **regidx_seq_names(regidx_t *idx, int *n)
+{
+ *n = idx->nseq;
+ return idx->seq_names;
+}
+
+int _regidx_build_index(regidx_t *idx)
+{
+ int iseq;
+ for (iseq=0; iseq<idx->nseq; iseq++)
+ {
+ reglist_t *list = &idx->seq[iseq];
+ int j,k, imax = 0; // max index bin
+ for (j=0; j<list->nregs; j++)
+ {
+ int ibeg = list->regs[j].start >> LIDX_SHIFT;
+ int iend = list->regs[j].end >> LIDX_SHIFT;
+ if ( imax < iend + 1 )
+ {
+ int old_imax = imax;
+ imax = iend + 1;
+ kroundup32(imax);
+ list->idx = (int*) realloc(list->idx, imax*sizeof(int));
+ for (k=old_imax; k<imax; k++) list->idx[k] = -1;
+ }
+ if ( ibeg==iend )
+ {
+ if ( list->idx[ibeg]<0 ) list->idx[ibeg] = j;
+ }
+ else
+ {
+ for (k=ibeg; k<=iend; k++)
+ if ( list->idx[k]<0 ) list->idx[k] = j;
+ }
+ list->nidx = iend + 1;
+ }
+ }
+ return 0;
+}
+
+int regidx_insert(regidx_t *idx, char *line)
+{
+ if ( !line )
+ return _regidx_build_index(idx);
+
+ char *chr_from, *chr_to;
+ reg_t reg;
+ int ret = idx->parse(line,&chr_from,&chr_to,®,idx->payload,idx->usr);
+ if ( ret==-2 ) return -1; // error
+ if ( ret==-1 ) return 0; // skip the line
+
+ int rid;
+ idx->str.l = 0;
+ kputsn(chr_from, chr_to-chr_from+1, &idx->str);
+ if ( khash_str2int_get(idx->seq2regs, idx->str.s, &rid)!=0 )
+ {
+ idx->nseq++;
+ int m_prev = idx->mseq;
+ hts_expand0(reglist_t,idx->nseq,idx->mseq,idx->seq);
+ hts_expand0(char*,idx->nseq,m_prev,idx->seq_names);
+ idx->seq_names[idx->nseq-1] = strdup(idx->str.s);
+ rid = khash_str2int_inc(idx->seq2regs, idx->seq_names[idx->nseq-1]);
+ }
+
+ reglist_t *list = &idx->seq[rid];
+ list->nregs++;
+ int m_prev = list->mregs;
+ hts_expand(reg_t,list->nregs,list->mregs,list->regs);
+ list->regs[list->nregs-1] = reg;
+ if ( idx->payload_size )
+ {
+ if ( m_prev < list->mregs ) list->payload = realloc(list->payload,idx->payload_size*list->mregs);
+ memcpy(list->payload + idx->payload_size*(list->nregs-1), idx->payload, idx->payload_size);
+ }
+
+ if ( idx->rid_prev==rid )
+ {
+ if ( idx->start_prev > reg.start || (idx->start_prev==reg.start && idx->end_prev>reg.end) )
+ {
+ fprintf(stderr,"The regions are not sorted: %s:%d-%d is before %s:%d-%d\n",
+ idx->str.s,idx->start_prev+1,idx->end_prev+1,idx->str.s,reg.start+1,reg.end+1);
+ return -1;
+ }
+ }
+ idx->rid_prev = rid;
+ idx->start_prev = reg.start;
+ idx->end_prev = reg.end;
+ return 0;
+}
+
+regidx_t *regidx_init(const char *fname, regidx_parse_f parser, regidx_free_f free_f, size_t payload_size, void *usr_dat)
+{
+ if ( !parser )
+ {
+ if ( !fname ) parser = regidx_parse_tab;
+ else
+ {
+ int len = strlen(fname);
+ if ( len>=7 && !strcasecmp(".bed.gz",fname+len-7) )
+ parser = regidx_parse_bed;
+ else if ( len>=8 && !strcasecmp(".bed.bgz",fname+len-8) )
+ parser = regidx_parse_bed;
+ else if ( len>=4 && !strcasecmp(".bed",fname+len-4) )
+ parser = regidx_parse_bed;
+ else
+ parser = regidx_parse_tab;
+ }
+ }
+
+ regidx_t *idx = (regidx_t*) calloc(1,sizeof(regidx_t));
+ idx->free = free_f;
+ idx->parse = parser;
+ idx->usr = usr_dat;
+ idx->seq2regs = khash_str2int_init();
+ idx->rid_prev = -1;
+ idx->start_prev = -1;
+ idx->end_prev = -1;
+ idx->payload_size = payload_size;
+ if ( payload_size ) idx->payload = malloc(payload_size);
+
+ if ( !fname ) return idx;
+
+ kstring_t str = {0,0,0};
+
+ htsFile *fp = hts_open(fname,"r");
+ if ( !fp ) goto error;
+
+ while ( hts_getline(fp, KS_SEP_LINE, &str) > 0 )
+ {
+ if ( regidx_insert(idx, str.s) ) goto error;
+ }
+ regidx_insert(idx, NULL);
+
+ free(str.s);
+ hts_close(fp);
+ return idx;
+
+error:
+ free(str.s);
+ if ( fp ) hts_close(fp);
+ regidx_destroy(idx);
+ return NULL;
+}
+
+void regidx_destroy(regidx_t *idx)
+{
+ int i, j;
+ for (i=0; i<idx->nseq; i++)
+ {
+ reglist_t *list = &idx->seq[i];
+ if ( idx->free )
+ {
+ for (j=0; j<list->nregs; j++)
+ idx->free(list->payload + idx->payload_size*j);
+ }
+ free(list->payload);
+ free(list->regs);
+ free(list->idx);
+ }
+ free(idx->seq_names);
+ free(idx->seq);
+ free(idx->str.s);
+ free(idx->payload);
+ khash_str2int_destroy_free(idx->seq2regs);
+ free(idx);
+}
+
+int regidx_overlap(regidx_t *idx, const char *chr, uint32_t from, uint32_t to, regitr_t *itr)
+{
+ if ( itr ) itr->i = itr->n = 0;
+
+ int iseq;
+ if ( khash_str2int_get(idx->seq2regs, chr, &iseq)!=0 ) return 0; // no such sequence
+
+ reglist_t *list = &idx->seq[iseq];
+ if ( !list->nregs ) return 0;
+
+ int i, ibeg = from>>LIDX_SHIFT;
+ int ireg = ibeg < list->nidx ? list->idx[ibeg] : list->idx[ list->nidx - 1 ];
+ if ( ireg < 0 )
+ {
+ // linear search; if slow, replace with binary search
+ if ( ibeg > list->nidx ) ibeg = list->nidx;
+ for (i=ibeg - 1; i>=0; i--)
+ if ( list->idx[i] >=0 ) break;
+ ireg = i>=0 ? list->idx[i] : 0;
+ }
+ for (i=ireg; i<list->nregs; i++)
+ {
+ if ( list->regs[i].start > to ) return 0; // no match
+ if ( list->regs[i].end >= from && list->regs[i].start <= to ) break; // found
+ }
+
+ if ( i>=list->nregs ) return 0; // no match
+
+ if ( !itr ) return 1;
+
+ itr->i = 0;
+ itr->n = list->nregs - i;
+ itr->reg = &idx->seq[iseq].regs[i];
+ if ( idx->payload_size )
+ itr->payload = idx->seq[iseq].payload + i*idx->payload_size;
+ else
+ itr->payload = NULL;
+
+ return 1;
+}
+
+int regidx_parse_bed(const char *line, char **chr_beg, char **chr_end, reg_t *reg, void *payload, void *usr)
+{
+ char *ss = (char*) line;
+ while ( *ss && isspace(*ss) ) ss++;
+ if ( !*ss ) return -1; // skip blank lines
+ if ( *ss=='#' ) return -1; // skip comments
+
+ char *se = ss;
+ while ( *se && !isspace(*se) ) se++;
+ if ( !*se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; }
+
+ *chr_beg = ss;
+ *chr_end = se-1;
+
+ ss = se+1;
+ reg->start = hts_parse_decimal(ss, &se, 0);
+ if ( ss==se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; }
+
+ ss = se+1;
+ reg->end = hts_parse_decimal(ss, &se, 0) - 1;
+ if ( ss==se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; }
+
+ return 0;
+}
+
+int regidx_parse_tab(const char *line, char **chr_beg, char **chr_end, reg_t *reg, void *payload, void *usr)
+{
+ char *ss = (char*) line;
+ while ( *ss && isspace(*ss) ) ss++;
+ if ( !*ss ) return -1; // skip blank lines
+ if ( *ss=='#' ) return -1; // skip comments
+
+ char *se = ss;
+ while ( *se && !isspace(*se) ) se++;
+ if ( !*se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; }
+
+ *chr_beg = ss;
+ *chr_end = se-1;
+
+ ss = se+1;
+ reg->start = hts_parse_decimal(ss, &se, 0) - 1;
+ if ( ss==se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; }
+
+ if ( !se[0] || !se[1] )
+ reg->end = reg->start;
+ else
+ {
+ ss = se+1;
+ reg->end = hts_parse_decimal(ss, &se, 0);
+ if ( ss==se ) reg->end = reg->start;
+ else reg->end--;
+ }
+
+ return 0;
+}
+
--- /dev/null
+'\" t
+.TH sam 5 "August 2013" "htslib" "Bioinformatics formats"
+.SH NAME
+sam \- Sequence Alignment/Map file format
+.\"
+.\" Copyright (C) 2009, 2013 Genome Research Ltd.
+.\"
+.\" Author: Heng Li <lh3@sanger.ac.uk>
+.\"
+.\" Permission is hereby granted, free of charge, to any person obtaining a
+.\" copy of this software and associated documentation files (the "Software"),
+.\" to deal in the Software without restriction, including without limitation
+.\" the rights to use, copy, modify, merge, publish, distribute, sublicense,
+.\" and/or sell copies of the Software, and to permit persons to whom the
+.\" Software is furnished to do so, subject to the following conditions:
+.\"
+.\" The above copyright notice and this permission notice shall be included in
+.\" all copies or substantial portions of the Software.
+.\"
+.\" THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+.\" IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+.\" FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+.\" THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+.\" LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+.\" FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+.\" DEALINGS IN THE SOFTWARE.
+.\"
+.SH DESCRIPTION
+Sequence Alignment/Map (SAM) format is TAB-delimited. Apart from the header lines, which are started
+with the `@' symbol, each alignment line consists of:
+.TS
+nlbl.
+1 QNAME Query template/pair NAME
+2 FLAG bitwise FLAG
+3 RNAME Reference sequence NAME
+4 POS 1-based leftmost POSition/coordinate of clipped sequence
+5 MAPQ MAPping Quality (Phred-scaled)
+6 CIGAR extended CIGAR string
+7 MRNM Mate Reference sequence NaMe (`=' if same as RNAME)
+8 MPOS 1-based Mate POSistion
+9 TLEN inferred Template LENgth (insert size)
+10 SEQ query SEQuence on the same strand as the reference
+11 QUAL query QUALity (ASCII-33 gives the Phred base quality)
+12+ OPT variable OPTional fields in the format TAG:VTYPE:VALUE
+.TE
+.PP
+Each bit in the FLAG field is defined as:
+.TS
+lcbl.
+0x0001 p the read is paired in sequencing
+0x0002 P the read is mapped in a proper pair
+0x0004 u the query sequence itself is unmapped
+0x0008 U the mate is unmapped
+0x0010 r strand of the query (1 for reverse)
+0x0020 R strand of the mate
+0x0040 1 the read is the first read in a pair
+0x0080 2 the read is the second read in a pair
+0x0100 s the alignment is not primary
+0x0200 f the read fails platform/vendor quality checks
+0x0400 d the read is either a PCR or an optical duplicate
+0x0800 S the alignment is supplementary
+.TE
+.P
+where the second column gives the string representation of the FLAG field.
+.SH SEE ALSO
+.TP
+https://github.com/samtools/hts-specs
+The full SAM/BAM file format specification
--- /dev/null
+/* sam.c -- SAM and BAM file I/O and manipulation.
+
+ Copyright (C) 2008-2010, 2012-2016 Genome Research Ltd.
+ Copyright (C) 2010, 2012, 2013 Broad Institute.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <stdlib.h>
+#include <string.h>
+#include <errno.h>
+#include <ctype.h>
+#include <zlib.h>
+#include "htslib/sam.h"
+#include "htslib/bgzf.h"
+#include "cram/cram.h"
+#include "hts_internal.h"
+#include "htslib/hfile.h"
+
+#include "htslib/khash.h"
+KHASH_DECLARE(s2i, kh_cstr_t, int64_t)
+
+typedef khash_t(s2i) sdict_t;
+
+/**********************
+ *** BAM header I/O ***
+ **********************/
+
+bam_hdr_t *bam_hdr_init()
+{
+ return (bam_hdr_t*)calloc(1, sizeof(bam_hdr_t));
+}
+
+void bam_hdr_destroy(bam_hdr_t *h)
+{
+ int32_t i;
+ if (h == NULL) return;
+ if (h->target_name) {
+ for (i = 0; i < h->n_targets; ++i)
+ free(h->target_name[i]);
+ free(h->target_name);
+ free(h->target_len);
+ }
+ free(h->text); free(h->cigar_tab);
+ if (h->sdict) kh_destroy(s2i, (sdict_t*)h->sdict);
+ free(h);
+}
+
+bam_hdr_t *bam_hdr_dup(const bam_hdr_t *h0)
+{
+ if (h0 == NULL) return NULL;
+ bam_hdr_t *h;
+ if ((h = bam_hdr_init()) == NULL) return NULL;
+ // copy the simple data
+ h->n_targets = h0->n_targets;
+ h->ignore_sam_err = h0->ignore_sam_err;
+ h->l_text = h0->l_text;
+ // Then the pointery stuff
+ h->cigar_tab = NULL;
+ h->sdict = NULL;
+ // TODO Check for memory allocation failures
+ h->text = (char*)calloc(h->l_text + 1, 1);
+ memcpy(h->text, h0->text, h->l_text);
+ h->target_len = (uint32_t*)calloc(h->n_targets, sizeof(uint32_t));
+ h->target_name = (char**)calloc(h->n_targets, sizeof(char*));
+ int i;
+ for (i = 0; i < h->n_targets; ++i) {
+ h->target_len[i] = h0->target_len[i];
+ h->target_name[i] = strdup(h0->target_name[i]);
+ }
+ return h;
+}
+
+
+static bam_hdr_t *hdr_from_dict(sdict_t *d)
+{
+ bam_hdr_t *h;
+ khint_t k;
+ h = bam_hdr_init();
+ h->sdict = d;
+ h->n_targets = kh_size(d);
+ // TODO Check for memory allocation failures
+ h->target_len = (uint32_t*)malloc(sizeof(uint32_t) * h->n_targets);
+ h->target_name = (char**)malloc(sizeof(char*) * h->n_targets);
+ for (k = kh_begin(d); k != kh_end(d); ++k) {
+ if (!kh_exist(d, k)) continue;
+ h->target_name[kh_val(d, k)>>32] = (char*)kh_key(d, k);
+ h->target_len[kh_val(d, k)>>32] = kh_val(d, k)<<32>>32;
+ kh_val(d, k) >>= 32;
+ }
+ return h;
+}
+
+bam_hdr_t *bam_hdr_read(BGZF *fp)
+{
+ bam_hdr_t *h;
+ char buf[4];
+ int magic_len, has_EOF;
+ int32_t i, name_len, num_names = 0;
+ size_t bufsize;
+ ssize_t bytes;
+ // check EOF
+ has_EOF = bgzf_check_EOF(fp);
+ if (has_EOF < 0) {
+ perror("[W::bam_hdr_read] bgzf_check_EOF");
+ } else if (has_EOF == 0 && hts_verbose >= 2)
+ fprintf(stderr, "[W::%s] EOF marker is absent. The input is probably truncated.\n", __func__);
+ // read "BAM1"
+ magic_len = bgzf_read(fp, buf, 4);
+ if (magic_len != 4 || strncmp(buf, "BAM\1", 4)) {
+ if (hts_verbose >= 1) fprintf(stderr, "[E::%s] invalid BAM binary header\n", __func__);
+ return 0;
+ }
+ h = bam_hdr_init();
+ if (!h) goto nomem;
+
+ // read plain text and the number of reference sequences
+ bytes = bgzf_read(fp, &h->l_text, 4);
+ if (bytes != 4) goto read_err;
+ if (fp->is_be) ed_swap_4p(&h->l_text);
+
+ bufsize = ((size_t) h->l_text) + 1;
+ if (bufsize < h->l_text) goto nomem; // so large that adding 1 overflowed
+ h->text = (char*)malloc(bufsize);
+ if (!h->text) goto nomem;
+ h->text[h->l_text] = 0; // make sure it is NULL terminated
+ bytes = bgzf_read(fp, h->text, h->l_text);
+ if (bytes != h->l_text) goto read_err;
+
+ bytes = bgzf_read(fp, &h->n_targets, 4);
+ if (bytes != 4) goto read_err;
+ if (fp->is_be) ed_swap_4p(&h->n_targets);
+
+ if (h->n_targets < 0) goto invalid;
+
+ // read reference sequence names and lengths
+ if (h->n_targets > 0) {
+ h->target_name = (char**)calloc(h->n_targets, sizeof(char*));
+ if (!h->target_name) goto nomem;
+ h->target_len = (uint32_t*)calloc(h->n_targets, sizeof(uint32_t));
+ if (!h->target_len) goto nomem;
+ }
+ else {
+ h->target_name = NULL;
+ h->target_len = NULL;
+ }
+
+ for (i = 0; i != h->n_targets; ++i) {
+ bytes = bgzf_read(fp, &name_len, 4);
+ if (bytes != 4) goto read_err;
+ if (fp->is_be) ed_swap_4p(&name_len);
+ if (name_len <= 0) goto invalid;
+
+ h->target_name[i] = (char*)malloc(name_len);
+ if (!h->target_name[i]) goto nomem;
+ num_names++;
+
+ bytes = bgzf_read(fp, h->target_name[i], name_len);
+ if (bytes != name_len) goto read_err;
+
+ if (h->target_name[i][name_len - 1] != '\0') {
+ /* Fix missing NUL-termination. Is this being too nice?
+ We could alternatively bail out with an error. */
+ char *new_name;
+ if (name_len == INT32_MAX) goto invalid;
+ new_name = realloc(h->target_name[i], name_len + 1);
+ if (new_name == NULL) goto nomem;
+ h->target_name[i] = new_name;
+ h->target_name[i][name_len] = '\0';
+ }
+
+ bytes = bgzf_read(fp, &h->target_len[i], 4);
+ if (bytes != 4) goto read_err;
+ if (fp->is_be) ed_swap_4p(&h->target_len[i]);
+ }
+ return h;
+
+ nomem:
+ if (hts_verbose >= 1) fprintf(stderr, "[E::%s] out of memory\n", __func__);
+ goto clean;
+
+ read_err:
+ if (hts_verbose >= 1) {
+ if (bytes < 0) {
+ fprintf(stderr, "[E::%s] error reading BGZF stream\n", __func__);
+ } else {
+ fprintf(stderr, "[E::%s] truncated bam header\n", __func__);
+ }
+ }
+ goto clean;
+
+ invalid:
+ if (hts_verbose >= 1) {
+ fprintf(stderr, "[E::%s] invalid BAM binary header\n", __func__);
+ }
+
+ clean:
+ if (h != NULL) {
+ h->n_targets = num_names; // ensure we free only allocated target_names
+ bam_hdr_destroy(h);
+ }
+ return NULL;
+}
+
+int bam_hdr_write(BGZF *fp, const bam_hdr_t *h)
+{
+ char buf[4];
+ int32_t i, name_len, x;
+ // write "BAM1"
+ strncpy(buf, "BAM\1", 4);
+ if (bgzf_write(fp, buf, 4) < 0) return -1;
+ // write plain text and the number of reference sequences
+ if (fp->is_be) {
+ x = ed_swap_4(h->l_text);
+ if (bgzf_write(fp, &x, 4) < 0) return -1;
+ if (h->l_text) {
+ if (bgzf_write(fp, h->text, h->l_text) < 0) return -1;
+ }
+ x = ed_swap_4(h->n_targets);
+ if (bgzf_write(fp, &x, 4) < 0) return -1;
+ } else {
+ if (bgzf_write(fp, &h->l_text, 4) < 0) return -1;
+ if (h->l_text) {
+ if (bgzf_write(fp, h->text, h->l_text) < 0) return -1;
+ }
+ if (bgzf_write(fp, &h->n_targets, 4) < 0) return -1;
+ }
+ // write sequence names and lengths
+ for (i = 0; i != h->n_targets; ++i) {
+ char *p = h->target_name[i];
+ name_len = strlen(p) + 1;
+ if (fp->is_be) {
+ x = ed_swap_4(name_len);
+ if (bgzf_write(fp, &x, 4) < 0) return -1;
+ } else {
+ if (bgzf_write(fp, &name_len, 4) < 0) return -1;
+ }
+ if (bgzf_write(fp, p, name_len) < 0) return -1;
+ if (fp->is_be) {
+ x = ed_swap_4(h->target_len[i]);
+ if (bgzf_write(fp, &x, 4) < 0) return -1;
+ } else {
+ if (bgzf_write(fp, &h->target_len[i], 4) < 0) return -1;
+ }
+ }
+ if (bgzf_flush(fp) < 0) return -1;
+ return 0;
+}
+
+int bam_name2id(bam_hdr_t *h, const char *ref)
+{
+ sdict_t *d = (sdict_t*)h->sdict;
+ khint_t k;
+ if (h->sdict == 0) {
+ int i, absent;
+ d = kh_init(s2i);
+ for (i = 0; i < h->n_targets; ++i) {
+ k = kh_put(s2i, d, h->target_name[i], &absent);
+ kh_val(d, k) = i;
+ }
+ h->sdict = d;
+ }
+ k = kh_get(s2i, d, ref);
+ return k == kh_end(d)? -1 : kh_val(d, k);
+}
+
+/*************************
+ *** BAM alignment I/O ***
+ *************************/
+
+bam1_t *bam_init1()
+{
+ return (bam1_t*)calloc(1, sizeof(bam1_t));
+}
+
+void bam_destroy1(bam1_t *b)
+{
+ if (b == 0) return;
+ free(b->data); free(b);
+}
+
+bam1_t *bam_copy1(bam1_t *bdst, const bam1_t *bsrc)
+{
+ uint8_t *data = bdst->data;
+ int m_data = bdst->m_data; // backup data and m_data
+ if (m_data < bsrc->l_data) { // double the capacity
+ m_data = bsrc->l_data; kroundup32(m_data);
+ data = (uint8_t*)realloc(data, m_data);
+ }
+ memcpy(data, bsrc->data, bsrc->l_data); // copy var-len data
+ *bdst = *bsrc; // copy the rest
+ // restore the backup
+ bdst->m_data = m_data;
+ bdst->data = data;
+ return bdst;
+}
+
+bam1_t *bam_dup1(const bam1_t *bsrc)
+{
+ if (bsrc == NULL) return NULL;
+ bam1_t *bdst = bam_init1();
+ if (bdst == NULL) return NULL;
+ return bam_copy1(bdst, bsrc);
+}
+
+int bam_cigar2qlen(int n_cigar, const uint32_t *cigar)
+{
+ int k, l;
+ for (k = l = 0; k < n_cigar; ++k)
+ if (bam_cigar_type(bam_cigar_op(cigar[k]))&1)
+ l += bam_cigar_oplen(cigar[k]);
+ return l;
+}
+
+int bam_cigar2rlen(int n_cigar, const uint32_t *cigar)
+{
+ int k, l;
+ for (k = l = 0; k < n_cigar; ++k)
+ if (bam_cigar_type(bam_cigar_op(cigar[k]))&2)
+ l += bam_cigar_oplen(cigar[k]);
+ return l;
+}
+
+int32_t bam_endpos(const bam1_t *b)
+{
+ if (!(b->core.flag & BAM_FUNMAP) && b->core.n_cigar > 0)
+ return b->core.pos + bam_cigar2rlen(b->core.n_cigar, bam_get_cigar(b));
+ else
+ return b->core.pos + 1;
+}
+
+static inline int aux_type2size(uint8_t type)
+{
+ switch (type) {
+ case 'A': case 'c': case 'C':
+ return 1;
+ case 's': case 'S':
+ return 2;
+ case 'i': case 'I': case 'f':
+ return 4;
+ case 'd':
+ return 8;
+ case 'Z': case 'H': case 'B':
+ return type;
+ default:
+ return 0;
+ }
+}
+
+static void swap_data(const bam1_core_t *c, int l_data, uint8_t *data, int is_host)
+{
+ uint8_t *s;
+ uint32_t *cigar = (uint32_t*)(data + c->l_qname);
+ uint32_t i, n;
+ s = data + c->n_cigar*4 + c->l_qname + c->l_qseq + (c->l_qseq + 1)/2;
+ for (i = 0; i < c->n_cigar; ++i) ed_swap_4p(&cigar[i]);
+ while (s < data + l_data) {
+ int size;
+ s += 2; // skip key
+ size = aux_type2size(*s); ++s; // skip type
+ switch (size) {
+ case 1: ++s; break;
+ case 2: ed_swap_2p(s); s += 2; break;
+ case 4: ed_swap_4p(s); s += 4; break;
+ case 8: ed_swap_8p(s); s += 8; break;
+ case 'Z':
+ case 'H':
+ while (*s) ++s;
+ ++s;
+ break;
+ case 'B':
+ size = aux_type2size(*s); ++s;
+ if (is_host) memcpy(&n, s, 4), ed_swap_4p(s);
+ else ed_swap_4p(s), memcpy(&n, s, 4);
+ s += 4;
+ switch (size) {
+ case 1: s += n; break;
+ case 2: for (i = 0; i < n; ++i, s += 2) ed_swap_2p(s); break;
+ case 4: for (i = 0; i < n; ++i, s += 4) ed_swap_4p(s); break;
+ case 8: for (i = 0; i < n; ++i, s += 8) ed_swap_8p(s); break;
+ }
+ break;
+ }
+ }
+}
+
+int bam_read1(BGZF *fp, bam1_t *b)
+{
+ bam1_core_t *c = &b->core;
+ int32_t block_len, ret, i;
+ uint32_t x[8];
+ if ((ret = bgzf_read(fp, &block_len, 4)) != 4) {
+ if (ret == 0) return -1; // normal end-of-file
+ else return -2; // truncated
+ }
+ if (bgzf_read(fp, x, 32) != 32) return -3;
+ if (fp->is_be) {
+ ed_swap_4p(&block_len);
+ for (i = 0; i < 8; ++i) ed_swap_4p(x + i);
+ }
+ c->tid = x[0]; c->pos = x[1];
+ c->bin = x[2]>>16; c->qual = x[2]>>8&0xff; c->l_qname = x[2]&0xff;
+ c->flag = x[3]>>16; c->n_cigar = x[3]&0xffff;
+ c->l_qseq = x[4];
+ c->mtid = x[5]; c->mpos = x[6]; c->isize = x[7];
+ b->l_data = block_len - 32;
+ if (b->l_data < 0 || c->l_qseq < 0 || c->l_qname < 1) return -4;
+ if ((char *)bam_get_aux(b) - (char *)b->data > b->l_data)
+ return -4;
+ if (b->m_data < b->l_data) {
+ b->m_data = b->l_data;
+ kroundup32(b->m_data);
+ b->data = (uint8_t*)realloc(b->data, b->m_data);
+ if (!b->data)
+ return -4;
+ }
+ if (bgzf_read(fp, b->data, b->l_data) != b->l_data) return -4;
+ //b->l_aux = b->l_data - c->n_cigar * 4 - c->l_qname - c->l_qseq - (c->l_qseq+1)/2;
+ if (fp->is_be) swap_data(c, b->l_data, b->data, 0);
+ return 4 + block_len;
+}
+
+int bam_write1(BGZF *fp, const bam1_t *b)
+{
+ const bam1_core_t *c = &b->core;
+ uint32_t x[8], block_len = b->l_data + 32, y;
+ int i, ok;
+ x[0] = c->tid;
+ x[1] = c->pos;
+ x[2] = (uint32_t)c->bin<<16 | c->qual<<8 | c->l_qname;
+ x[3] = (uint32_t)c->flag<<16 | c->n_cigar;
+ x[4] = c->l_qseq;
+ x[5] = c->mtid;
+ x[6] = c->mpos;
+ x[7] = c->isize;
+ ok = (bgzf_flush_try(fp, 4 + block_len) >= 0);
+ if (fp->is_be) {
+ for (i = 0; i < 8; ++i) ed_swap_4p(x + i);
+ y = block_len;
+ if (ok) ok = (bgzf_write(fp, ed_swap_4p(&y), 4) >= 0);
+ swap_data(c, b->l_data, b->data, 1);
+ } else {
+ if (ok) ok = (bgzf_write(fp, &block_len, 4) >= 0);
+ }
+ if (ok) ok = (bgzf_write(fp, x, 32) >= 0);
+ if (ok) ok = (bgzf_write(fp, b->data, b->l_data) >= 0);
+ if (fp->is_be) swap_data(c, b->l_data, b->data, 0);
+ return ok? 4 + block_len : -1;
+}
+
+/********************
+ *** BAM indexing ***
+ ********************/
+
+static hts_idx_t *bam_index(BGZF *fp, int min_shift)
+{
+ int n_lvls, i, fmt, ret;
+ bam1_t *b;
+ hts_idx_t *idx;
+ bam_hdr_t *h;
+ h = bam_hdr_read(fp);
+ if (h == NULL) return NULL;
+ if (min_shift > 0) {
+ int64_t max_len = 0, s;
+ for (i = 0; i < h->n_targets; ++i)
+ if (max_len < h->target_len[i]) max_len = h->target_len[i];
+ max_len += 256;
+ for (n_lvls = 0, s = 1<<min_shift; max_len > s; ++n_lvls, s <<= 3);
+ fmt = HTS_FMT_CSI;
+ } else min_shift = 14, n_lvls = 5, fmt = HTS_FMT_BAI;
+ idx = hts_idx_init(h->n_targets, fmt, bgzf_tell(fp), min_shift, n_lvls);
+ bam_hdr_destroy(h);
+ b = bam_init1();
+ while ((ret = bam_read1(fp, b)) >= 0) {
+ ret = hts_idx_push(idx, b->core.tid, b->core.pos, bam_endpos(b), bgzf_tell(fp), !(b->core.flag&BAM_FUNMAP));
+ if (ret < 0) goto err; // unsorted
+ }
+ if (ret < -1) goto err; // corrupted BAM file
+
+ hts_idx_finish(idx, bgzf_tell(fp));
+ bam_destroy1(b);
+ return idx;
+
+err:
+ bam_destroy1(b);
+ hts_idx_destroy(idx);
+ return NULL;
+}
+
+int sam_index_build2(const char *fn, const char *fnidx, int min_shift)
+{
+ hts_idx_t *idx;
+ htsFile *fp;
+ int ret = 0;
+
+ if ((fp = hts_open(fn, "r")) == 0) return -2;
+ switch (fp->format.format) {
+ case cram:
+ ret = cram_index_build(fp->fp.cram, fn, fnidx);
+ break;
+
+ case bam:
+ idx = bam_index(fp->fp.bgzf, min_shift);
+ if (idx) {
+ ret = hts_idx_save_as(idx, fn, fnidx, (min_shift > 0)? HTS_FMT_CSI : HTS_FMT_BAI);
+ hts_idx_destroy(idx);
+ }
+ else ret = -1;
+ break;
+
+ default:
+ ret = -3;
+ break;
+ }
+ hts_close(fp);
+
+ return ret;
+}
+
+int sam_index_build(const char *fn, int min_shift)
+{
+ return sam_index_build2(fn, NULL, min_shift);
+}
+
+// Provide bam_index_build() symbol for binary compability with earlier HTSlib
+#undef bam_index_build
+int bam_index_build(const char *fn, int min_shift)
+{
+ return sam_index_build2(fn, NULL, min_shift);
+}
+
+static int bam_readrec(BGZF *fp, void *ignored, void *bv, int *tid, int *beg, int *end)
+{
+ bam1_t *b = bv;
+ int ret;
+ if ((ret = bam_read1(fp, b)) >= 0) {
+ *tid = b->core.tid;
+ *beg = b->core.pos;
+ *end = bam_endpos(b);
+ }
+ return ret;
+}
+
+// This is used only with read_rest=1 iterators, so need not set tid/beg/end.
+static int cram_readrec(BGZF *ignored, void *fpv, void *bv, int *tid, int *beg, int *end)
+{
+ htsFile *fp = fpv;
+ bam1_t *b = bv;
+ return cram_get_bam_seq(fp->fp.cram, &b);
+}
+
+// This is used only with read_rest=1 iterators, so need not set tid/beg/end.
+static int sam_bam_cram_readrec(BGZF *bgzfp, void *fpv, void *bv, int *tid, int *beg, int *end)
+{
+ htsFile *fp = fpv;
+ bam1_t *b = bv;
+ switch (fp->format.format) {
+ case bam: return bam_read1(bgzfp, b);
+ case cram: return cram_get_bam_seq(fp->fp.cram, &b);
+ default:
+ // TODO Need headers available to implement this for SAM files
+ fprintf(stderr, "[sam_bam_cram_readrec] Not implemented for SAM files -- Exiting\n");
+ abort();
+ }
+}
+
+hts_idx_t *sam_index_load2(htsFile *fp, const char *fn, const char *fnidx)
+{
+ switch (fp->format.format) {
+ case bam:
+ return fnidx? hts_idx_load2(fn, fnidx) : hts_idx_load(fn, HTS_FMT_BAI);
+
+ case cram: {
+ if (cram_index_load(fp->fp.cram, fn, fnidx) < 0) return NULL;
+ // Cons up a fake "index" just pointing at the associated cram_fd:
+ hts_cram_idx_t *idx = malloc(sizeof (hts_cram_idx_t));
+ if (idx == NULL) return NULL;
+ idx->fmt = HTS_FMT_CRAI;
+ idx->cram = fp->fp.cram;
+ return (hts_idx_t *) idx;
+ }
+
+ default:
+ return NULL; // TODO Would use tbx_index_load if it returned hts_idx_t
+ }
+}
+
+hts_idx_t *sam_index_load(htsFile *fp, const char *fn)
+{
+ return sam_index_load2(fp, fn, NULL);
+}
+
+static hts_itr_t *cram_itr_query(const hts_idx_t *idx, int tid, int beg, int end, hts_readrec_func *readrec)
+{
+ const hts_cram_idx_t *cidx = (const hts_cram_idx_t *) idx;
+ hts_itr_t *iter = (hts_itr_t *) calloc(1, sizeof(hts_itr_t));
+ if (iter == NULL) return NULL;
+
+ // Cons up a dummy iterator for which hts_itr_next() will simply invoke
+ // the readrec function:
+ iter->read_rest = 1;
+ iter->off = NULL;
+ iter->bins.a = NULL;
+ iter->readrec = readrec;
+
+ if (tid >= 0 || tid == HTS_IDX_NOCOOR) {
+ cram_range r = { tid == HTS_IDX_NOCOOR ? -1 : tid, beg+1, end };
+ int ret = cram_set_option(cidx->cram, CRAM_OPT_RANGE, &r);
+
+ iter->curr_off = 0;
+ // The following fields are not required by hts_itr_next(), but are
+ // filled in in case user code wants to look at them.
+ iter->tid = tid;
+ iter->beg = beg;
+ iter->end = end;
+
+ switch (ret) {
+ case 0:
+ break;
+
+ case -2:
+ // No data vs this ref, so mark iterator as completed.
+ // Same as HTS_IDX_NONE.
+ iter->finished = 1;
+ break;
+
+ default:
+ free(iter);
+ return NULL;
+ }
+ }
+ else switch (tid) {
+ case HTS_IDX_REST:
+ iter->curr_off = 0;
+ break;
+ case HTS_IDX_NONE:
+ iter->curr_off = 0;
+ iter->finished = 1;
+ break;
+ default:
+ fprintf(stderr, "[cram_itr_query] tid=%d not implemented for CRAM files -- Exiting\n", tid);
+ abort();
+ break;
+ }
+
+ return iter;
+}
+
+hts_itr_t *sam_itr_queryi(const hts_idx_t *idx, int tid, int beg, int end)
+{
+ const hts_cram_idx_t *cidx = (const hts_cram_idx_t *) idx;
+ if (idx == NULL)
+ return hts_itr_query(NULL, tid, beg, end, sam_bam_cram_readrec);
+ else if (cidx->fmt == HTS_FMT_CRAI)
+ return cram_itr_query(idx, tid, beg, end, cram_readrec);
+ else
+ return hts_itr_query(idx, tid, beg, end, bam_readrec);
+}
+
+static int cram_name2id(void *fdv, const char *ref)
+{
+ cram_fd *fd = (cram_fd *) fdv;
+ return sam_hdr_name2ref(fd->header, ref);
+}
+
+hts_itr_t *sam_itr_querys(const hts_idx_t *idx, bam_hdr_t *hdr, const char *region)
+{
+ const hts_cram_idx_t *cidx = (const hts_cram_idx_t *) idx;
+ if (cidx->fmt == HTS_FMT_CRAI)
+ return hts_itr_querys(idx, region, cram_name2id, cidx->cram, cram_itr_query, cram_readrec);
+ else
+ return hts_itr_querys(idx, region, (hts_name2id_f)(bam_name2id), hdr, hts_itr_query, bam_readrec);
+}
+
+/**********************
+ *** SAM header I/O ***
+ **********************/
+
+#include "htslib/kseq.h"
+#include "htslib/kstring.h"
+
+bam_hdr_t *sam_hdr_parse(int l_text, const char *text)
+{
+ const char *q, *r, *p;
+ khash_t(s2i) *d;
+ d = kh_init(s2i);
+ for (p = text; *p; ++p) {
+ if (strncmp(p, "@SQ\t", 4) == 0) {
+ char *sn = 0;
+ int ln = -1;
+ for (q = p + 4;; ++q) {
+ if (strncmp(q, "SN:", 3) == 0) {
+ q += 3;
+ for (r = q; *r != '\t' && *r != '\n' && *r != '\0'; ++r);
+ sn = (char*)calloc(r - q + 1, 1);
+ strncpy(sn, q, r - q);
+ q = r;
+ } else if (strncmp(q, "LN:", 3) == 0)
+ ln = strtol(q + 3, (char**)&q, 10);
+ while (*q != '\t' && *q != '\n' && *q != '\0') ++q;
+ if (*q == '\0' || *q == '\n') break;
+ }
+ p = q;
+ if (sn && ln >= 0) {
+ khint_t k;
+ int absent;
+ k = kh_put(s2i, d, sn, &absent);
+ if (!absent) {
+ if (hts_verbose >= 2)
+ fprintf(stderr, "[W::%s] duplicated sequence '%s'\n", __func__, sn);
+ free(sn);
+ } else kh_val(d, k) = (int64_t)(kh_size(d) - 1)<<32 | ln;
+ }
+ }
+ while (*p != '\0' && *p != '\n') ++p;
+ }
+ return hdr_from_dict(d);
+}
+
+bam_hdr_t *sam_hdr_read(htsFile *fp)
+{
+ switch (fp->format.format) {
+ case bam:
+ return bam_hdr_read(fp->fp.bgzf);
+
+ case cram:
+ return cram_header_to_bam(fp->fp.cram->header);
+
+ case sam: {
+ kstring_t str;
+ bam_hdr_t *h;
+ int has_SQ = 0;
+ str.l = str.m = 0; str.s = 0;
+ while (hts_getline(fp, KS_SEP_LINE, &fp->line) >= 0) {
+ if (fp->line.s[0] != '@') break;
+ if (fp->line.l > 3 && strncmp(fp->line.s,"@SQ",3) == 0) has_SQ = 1;
+ kputsn(fp->line.s, fp->line.l, &str);
+ kputc('\n', &str);
+ }
+ if (! has_SQ && fp->fn_aux) {
+ char line[2048];
+ FILE *f = fopen(fp->fn_aux, "r");
+ if (f == NULL) return NULL;
+ while (fgets(line, sizeof line, f)) {
+ const char *name = strtok(line, "\t");
+ const char *length = strtok(NULL, "\t");
+ ksprintf(&str, "@SQ\tSN:%s\tLN:%s\n", name, length);
+ }
+ fclose(f);
+ }
+ if (str.l == 0) kputsn("", 0, &str);
+ h = sam_hdr_parse(str.l, str.s);
+ h->l_text = str.l; h->text = str.s;
+ return h;
+ }
+
+ default:
+ abort();
+ }
+}
+
+int sam_hdr_write(htsFile *fp, const bam_hdr_t *h)
+{
+ switch (fp->format.format) {
+ case binary_format:
+ fp->format.category = sequence_data;
+ fp->format.format = bam;
+ /* fall-through */
+ case bam:
+ if (bam_hdr_write(fp->fp.bgzf, h) < 0) return -1;
+ break;
+
+ case cram: {
+ cram_fd *fd = fp->fp.cram;
+ SAM_hdr *hdr = bam_header_to_cram((bam_hdr_t *)h);
+ if (! hdr) return -1;
+ if (cram_set_header(fd, hdr) < 0) return -1;
+ if (fp->fn_aux)
+ cram_load_reference(fd, fp->fn_aux);
+ if (cram_write_SAM_hdr(fd, fd->header) < 0) return -1;
+ }
+ break;
+
+ case text_format:
+ fp->format.category = sequence_data;
+ fp->format.format = sam;
+ /* fall-through */
+ case sam: {
+ char *p;
+ hputs(h->text, fp->fp.hfile);
+ p = strstr(h->text, "@SQ\t"); // FIXME: we need a loop to make sure "@SQ\t" does not match something unwanted!!!
+ if (p == 0) {
+ int i;
+ for (i = 0; i < h->n_targets; ++i) {
+ fp->line.l = 0;
+ kputsn("@SQ\tSN:", 7, &fp->line); kputs(h->target_name[i], &fp->line);
+ kputsn("\tLN:", 4, &fp->line); kputw(h->target_len[i], &fp->line); kputc('\n', &fp->line);
+ if ( hwrite(fp->fp.hfile, fp->line.s, fp->line.l) != fp->line.l ) return -1;
+ }
+ }
+ if ( hflush(fp->fp.hfile) != 0 ) return -1;
+ }
+ break;
+
+ default:
+ abort();
+ }
+ return 0;
+}
+
+/**********************
+ *** SAM record I/O ***
+ **********************/
+
+int sam_parse1(kstring_t *s, bam_hdr_t *h, bam1_t *b)
+{
+#define _read_token(_p) (_p); for (; *(_p) && *(_p) != '\t'; ++(_p)); if (*(_p) != '\t') goto err_ret; *(_p)++ = 0
+#define _read_token_aux(_p) (_p); for (; *(_p) && *(_p) != '\t'; ++(_p)); *(_p)++ = 0 // this is different in that it does not test *(_p)=='\t'
+#define _get_mem(type_t, _x, _s, _l) ks_resize((_s), (_s)->l + (_l)); *(_x) = (type_t*)((_s)->s + (_s)->l); (_s)->l += (_l)
+#define _parse_err(cond, msg) do { if ((cond) && hts_verbose >= 1) { fprintf(stderr, "[E::%s] " msg "\n", __func__); goto err_ret; } } while (0)
+#define _parse_warn(cond, msg) if ((cond) && hts_verbose >= 2) fprintf(stderr, "[W::%s] " msg "\n", __func__)
+
+ uint8_t *t;
+ char *p = s->s, *q;
+ int i;
+ kstring_t str;
+ bam1_core_t *c = &b->core;
+
+ str.l = b->l_data = 0;
+ str.s = (char*)b->data; str.m = b->m_data;
+ memset(c, 0, 32);
+ if (h->cigar_tab == 0) {
+ h->cigar_tab = (int8_t*) malloc(128);
+ for (i = 0; i < 128; ++i)
+ h->cigar_tab[i] = -1;
+ for (i = 0; BAM_CIGAR_STR[i]; ++i)
+ h->cigar_tab[(int)BAM_CIGAR_STR[i]] = i;
+ }
+ // qname
+ q = _read_token(p);
+ _parse_warn(p - q <= 1, "empty query name");
+ _parse_err(p - q > 255, "query name too long");
+ kputsn_(q, p - q, &str);
+ c->l_qname = p - q;
+ // flag
+ c->flag = strtol(p, &p, 0);
+ if (*p++ != '\t') goto err_ret; // malformated flag
+ // chr
+ q = _read_token(p);
+ if (strcmp(q, "*")) {
+ _parse_err(h->n_targets == 0, "missing SAM header");
+ c->tid = bam_name2id(h, q);
+ _parse_warn(c->tid < 0, "urecognized reference name; treated as unmapped");
+ } else c->tid = -1;
+ // pos
+ c->pos = strtol(p, &p, 10) - 1;
+ if (*p++ != '\t') goto err_ret;
+ if (c->pos < 0 && c->tid >= 0) {
+ _parse_warn(1, "mapped query cannot have zero coordinate; treated as unmapped");
+ c->tid = -1;
+ }
+ if (c->tid < 0) c->flag |= BAM_FUNMAP;
+ // mapq
+ c->qual = strtol(p, &p, 10);
+ if (*p++ != '\t') goto err_ret;
+ // cigar
+ if (*p != '*') {
+ uint32_t *cigar;
+ size_t n_cigar = 0;
+ for (q = p; *p && *p != '\t'; ++p)
+ if (!isdigit(*p)) ++n_cigar;
+ if (*p++ != '\t') goto err_ret;
+ _parse_err(n_cigar == 0, "no CIGAR operations");
+ _parse_err(n_cigar >= 65536, "too many CIGAR operations");
+ c->n_cigar = n_cigar;
+ _get_mem(uint32_t, &cigar, &str, c->n_cigar * sizeof(uint32_t));
+ for (i = 0; i < c->n_cigar; ++i, ++q) {
+ int op;
+ cigar[i] = strtol(q, &q, 10)<<BAM_CIGAR_SHIFT;
+ op = (uint8_t)*q >= 128? -1 : h->cigar_tab[(int)*q];
+ _parse_err(op < 0, "unrecognized CIGAR operator");
+ cigar[i] |= op;
+ }
+ // can't use bam_endpos() directly as some fields not yet set up
+ i = (!(c->flag&BAM_FUNMAP))? bam_cigar2rlen(c->n_cigar, cigar) : 1;
+ } else {
+ _parse_warn(!(c->flag&BAM_FUNMAP), "mapped query must have a CIGAR; treated as unmapped");
+ c->flag |= BAM_FUNMAP;
+ q = _read_token(p);
+ i = 1;
+ }
+ c->bin = hts_reg2bin(c->pos, c->pos + i, 14, 5);
+ // mate chr
+ q = _read_token(p);
+ if (strcmp(q, "=") == 0) {
+ c->mtid = c->tid;
+ } else if (strcmp(q, "*") == 0) {
+ c->mtid = -1;
+ } else {
+ c->mtid = bam_name2id(h, q);
+ _parse_warn(c->mtid < 0, "urecognized mate reference name; treated as unmapped");
+ }
+ // mpos
+ c->mpos = strtol(p, &p, 10) - 1;
+ if (*p++ != '\t') goto err_ret;
+ if (c->mpos < 0 && c->mtid >= 0) {
+ _parse_warn(1, "mapped mate cannot have zero coordinate; treated as unmapped");
+ c->mtid = -1;
+ }
+ // tlen
+ c->isize = strtol(p, &p, 10);
+ if (*p++ != '\t') goto err_ret;
+ // seq
+ q = _read_token(p);
+ if (strcmp(q, "*")) {
+ c->l_qseq = p - q - 1;
+ i = bam_cigar2qlen(c->n_cigar, (uint32_t*)(str.s + c->l_qname));
+ _parse_err(c->n_cigar && i != c->l_qseq, "CIGAR and query sequence are of different length");
+ i = (c->l_qseq + 1) >> 1;
+ _get_mem(uint8_t, &t, &str, i);
+ memset(t, 0, i);
+ for (i = 0; i < c->l_qseq; ++i)
+ t[i>>1] |= seq_nt16_table[(int)q[i]] << ((~i&1)<<2);
+ } else c->l_qseq = 0;
+ // qual
+ q = _read_token_aux(p);
+ _get_mem(uint8_t, &t, &str, c->l_qseq);
+ if (strcmp(q, "*")) {
+ _parse_err(p - q - 1 != c->l_qseq, "SEQ and QUAL are of different length");
+ for (i = 0; i < c->l_qseq; ++i) t[i] = q[i] - 33;
+ } else memset(t, 0xff, c->l_qseq);
+ // aux
+ // Note that (like the bam1_core_t fields) this aux data in b->data is
+ // stored in host endianness; so there is no byte swapping needed here.
+ while (p < s->s + s->l) {
+ uint8_t type;
+ q = _read_token_aux(p); // FIXME: can be accelerated for long 'B' arrays
+ _parse_err(p - q - 1 < 6, "incomplete aux field");
+ kputsn_(q, 2, &str);
+ q += 3; type = *q++; ++q; // q points to value
+ if (type == 'A' || type == 'a' || type == 'c' || type == 'C') {
+ kputc_('A', &str);
+ kputc_(*q, &str);
+ } else if (type == 'i' || type == 'I') {
+ if (*q == '-') {
+ long x = strtol(q, &q, 10);
+ if (x >= INT8_MIN) {
+ kputc_('c', &str); kputc_(x, &str);
+ } else if (x >= INT16_MIN) {
+ int16_t y = x;
+ kputc_('s', &str); kputsn_((char*)&y, 2, &str);
+ } else {
+ int32_t y = x;
+ kputc_('i', &str); kputsn_(&y, 4, &str);
+ }
+ } else {
+ unsigned long x = strtoul(q, &q, 10);
+ if (x <= UINT8_MAX) {
+ kputc_('C', &str); kputc_(x, &str);
+ } else if (x <= UINT16_MAX) {
+ uint16_t y = x;
+ kputc_('S', &str); kputsn_(&y, 2, &str);
+ } else {
+ uint32_t y = x;
+ kputc_('I', &str); kputsn_(&y, 4, &str);
+ }
+ }
+ } else if (type == 'f') {
+ float x;
+ x = strtod(q, &q);
+ kputc_('f', &str); kputsn_(&x, 4, &str);
+ } else if (type == 'd') {
+ double x;
+ x = strtod(q, &q);
+ kputc_('d', &str); kputsn_(&x, 8, &str);
+ } else if (type == 'Z' || type == 'H') {
+ kputc_(type, &str);kputsn_(q, p - q, &str); // note that this include the trailing NULL
+ } else if (type == 'B') {
+ int32_t n;
+ char *r;
+ _parse_err(p - q - 1 < 3, "incomplete B-typed aux field");
+ type = *q++; // q points to the first ',' following the typing byte
+ for (r = q, n = 0; *r; ++r)
+ if (*r == ',') ++n;
+ kputc_('B', &str); kputc_(type, &str); kputsn_(&n, 4, &str);
+ // FIXME: to evaluate which is faster: a) aligned array and then memmove(); b) unaligned array; c) kputsn_()
+ if (type == 'c') while (q + 1 < p) { int8_t x = strtol(q + 1, &q, 0); kputc_(x, &str); }
+ else if (type == 'C') while (q + 1 < p) { uint8_t x = strtoul(q + 1, &q, 0); kputc_(x, &str); }
+ else if (type == 's') while (q + 1 < p) { int16_t x = strtol(q + 1, &q, 0); kputsn_(&x, 2, &str); }
+ else if (type == 'S') while (q + 1 < p) { uint16_t x = strtoul(q + 1, &q, 0); kputsn_(&x, 2, &str); }
+ else if (type == 'i') while (q + 1 < p) { int32_t x = strtol(q + 1, &q, 0); kputsn_(&x, 4, &str); }
+ else if (type == 'I') while (q + 1 < p) { uint32_t x = strtoul(q + 1, &q, 0); kputsn_(&x, 4, &str); }
+ else if (type == 'f') while (q + 1 < p) { float x = strtod(q + 1, &q); kputsn_(&x, 4, &str); }
+ else _parse_err(1, "unrecognized type");
+ } else _parse_err(1, "unrecognized type");
+ }
+ b->data = (uint8_t*)str.s; b->l_data = str.l; b->m_data = str.m;
+ return 0;
+
+#undef _parse_warn
+#undef _parse_err
+#undef _get_mem
+#undef _read_token_aux
+#undef _read_token
+err_ret:
+ b->data = (uint8_t*)str.s; b->l_data = str.l; b->m_data = str.m;
+ return -2;
+}
+
+int sam_read1(htsFile *fp, bam_hdr_t *h, bam1_t *b)
+{
+ switch (fp->format.format) {
+ case bam: {
+ int r = bam_read1(fp->fp.bgzf, b);
+ if (r >= 0) {
+ if (b->core.tid >= h->n_targets || b->core.tid < -1 ||
+ b->core.mtid >= h->n_targets || b->core.mtid < -1)
+ return -3;
+ }
+ return r;
+ }
+
+ case cram: {
+ int ret = cram_get_bam_seq(fp->fp.cram, &b);
+ return ret >= 0
+ ? ret
+ : (cram_eof(fp->fp.cram) ? -1 : -2);
+ }
+
+ case sam: {
+ int ret;
+err_recover:
+ if (fp->line.l == 0) {
+ ret = hts_getline(fp, KS_SEP_LINE, &fp->line);
+ if (ret < 0) return -1;
+ }
+ ret = sam_parse1(&fp->line, h, b);
+ fp->line.l = 0;
+ if (ret < 0) {
+ if (hts_verbose >= 1)
+ fprintf(stderr, "[W::%s] parse error at line %lld\n", __func__, (long long)fp->lineno);
+ if (h->ignore_sam_err) goto err_recover;
+ }
+ return ret;
+ }
+
+ default:
+ abort();
+ }
+}
+
+int sam_format1(const bam_hdr_t *h, const bam1_t *b, kstring_t *str)
+{
+ int i;
+ uint8_t *s;
+ const bam1_core_t *c = &b->core;
+
+ str->l = 0;
+ kputsn(bam_get_qname(b), c->l_qname-1, str); kputc('\t', str); // query name
+ kputw(c->flag, str); kputc('\t', str); // flag
+ if (c->tid >= 0) { // chr
+ kputs(h->target_name[c->tid] , str);
+ kputc('\t', str);
+ } else kputsn("*\t", 2, str);
+ kputw(c->pos + 1, str); kputc('\t', str); // pos
+ kputw(c->qual, str); kputc('\t', str); // qual
+ if (c->n_cigar) { // cigar
+ uint32_t *cigar = bam_get_cigar(b);
+ for (i = 0; i < c->n_cigar; ++i) {
+ kputw(bam_cigar_oplen(cigar[i]), str);
+ kputc(bam_cigar_opchr(cigar[i]), str);
+ }
+ } else kputc('*', str);
+ kputc('\t', str);
+ if (c->mtid < 0) kputsn("*\t", 2, str); // mate chr
+ else if (c->mtid == c->tid) kputsn("=\t", 2, str);
+ else {
+ kputs(h->target_name[c->mtid], str);
+ kputc('\t', str);
+ }
+ kputw(c->mpos + 1, str); kputc('\t', str); // mate pos
+ kputw(c->isize, str); kputc('\t', str); // template len
+ if (c->l_qseq) { // seq and qual
+ uint8_t *s = bam_get_seq(b);
+ for (i = 0; i < c->l_qseq; ++i) kputc("=ACMGRSVTWYHKDBN"[bam_seqi(s, i)], str);
+ kputc('\t', str);
+ s = bam_get_qual(b);
+ if (s[0] == 0xff) kputc('*', str);
+ else for (i = 0; i < c->l_qseq; ++i) kputc(s[i] + 33, str);
+ } else kputsn("*\t*", 3, str);
+
+ // FIXME change "s+N <= b->data+b->l_data" to "b->data+b->l_data - s >= N"
+ // (or equivalent) everywhere to avoid looking past the end of the array
+ s = bam_get_aux(b); // aux
+ while (s+4 <= b->data + b->l_data) {
+ uint8_t type, key[2];
+ key[0] = s[0]; key[1] = s[1];
+ s += 2; type = *s++;
+ kputc('\t', str); kputsn((char*)key, 2, str); kputc(':', str);
+ if (type == 'A') {
+ kputsn("A:", 2, str);
+ kputc(*s, str);
+ ++s;
+ } else if (type == 'C') {
+ kputsn("i:", 2, str);
+ kputw(*s, str);
+ ++s;
+ } else if (type == 'c') {
+ kputsn("i:", 2, str);
+ kputw(*(int8_t*)s, str);
+ ++s;
+ } else if (type == 'S') {
+ if (s+2 <= b->data + b->l_data) {
+ kputsn("i:", 2, str);
+ kputw(*(uint16_t*)s, str);
+ s += 2;
+ } else return -1;
+ } else if (type == 's') {
+ if (s+2 <= b->data + b->l_data) {
+ kputsn("i:", 2, str);
+ kputw(*(int16_t*)s, str);
+ s += 2;
+ } else return -1;
+ } else if (type == 'I') {
+ if (s+4 <= b->data + b->l_data) {
+ kputsn("i:", 2, str);
+ kputuw(*(uint32_t*)s, str);
+ s += 4;
+ } else return -1;
+ } else if (type == 'i') {
+ if (s+4 <= b->data + b->l_data) {
+ kputsn("i:", 2, str);
+ kputw(*(int32_t*)s, str);
+ s += 4;
+ } else return -1;
+ } else if (type == 'f') {
+ if (s+4 <= b->data + b->l_data) {
+ ksprintf(str, "f:%g", *(float*)s);
+ s += 4;
+ } else return -1;
+
+ } else if (type == 'd') {
+ if (s+8 <= b->data + b->l_data) {
+ ksprintf(str, "d:%g", *(double*)s);
+ s += 8;
+ } else return -1;
+ } else if (type == 'Z' || type == 'H') {
+ kputc(type, str); kputc(':', str);
+ while (s < b->data + b->l_data && *s) kputc(*s++, str);
+ if (s >= b->data + b->l_data)
+ return -1;
+ ++s;
+ } else if (type == 'B') {
+ uint8_t sub_type = *(s++);
+ int sub_type_size = aux_type2size(sub_type);
+ uint32_t n;
+ if (sub_type_size == 0 || b->data + b->l_data - s < 4)
+ return -1;
+ memcpy(&n, s, 4);
+ s += 4; // now points to the start of the array
+ if ((b->data + b->l_data - s) / sub_type_size < n)
+ return -1;
+ kputsn("B:", 2, str); kputc(sub_type, str); // write the typing
+ for (i = 0; i < n; ++i) { // FIXME: for better performance, put the loop after "if"
+ kputc(',', str);
+ if ('c' == sub_type) { kputw(*(int8_t*)s, str); ++s; }
+ else if ('C' == sub_type) { kputw(*(uint8_t*)s, str); ++s; }
+ else if ('s' == sub_type) { kputw(*(int16_t*)s, str); s += 2; }
+ else if ('S' == sub_type) { kputw(*(uint16_t*)s, str); s += 2; }
+ else if ('i' == sub_type) { kputw(*(int32_t*)s, str); s += 4; }
+ else if ('I' == sub_type) { kputuw(*(uint32_t*)s, str); s += 4; }
+ else if ('f' == sub_type) { ksprintf(str, "%g", *(float*)s); s += 4; }
+ else return -1;
+ }
+ }
+ }
+ return str->l;
+}
+
+int sam_write1(htsFile *fp, const bam_hdr_t *h, const bam1_t *b)
+{
+ switch (fp->format.format) {
+ case binary_format:
+ fp->format.category = sequence_data;
+ fp->format.format = bam;
+ /* fall-through */
+ case bam:
+ return bam_write1(fp->fp.bgzf, b);
+
+ case cram:
+ return cram_put_bam_seq(fp->fp.cram, (bam1_t *)b);
+
+ case text_format:
+ fp->format.category = sequence_data;
+ fp->format.format = sam;
+ /* fall-through */
+ case sam:
+ if (sam_format1(h, b, &fp->line) < 0) return -1;
+ kputc('\n', &fp->line);
+ if ( hwrite(fp->fp.hfile, fp->line.s, fp->line.l) != fp->line.l ) return -1;
+ return fp->line.l;
+
+ default:
+ abort();
+ }
+}
+
+/************************
+ *** Auxiliary fields ***
+ ************************/
+
+void bam_aux_append(bam1_t *b, const char tag[2], char type, int len, uint8_t *data)
+{
+ int ori_len = b->l_data;
+ b->l_data += 3 + len;
+ if (b->m_data < b->l_data) {
+ b->m_data = b->l_data;
+ kroundup32(b->m_data);
+ b->data = (uint8_t*)realloc(b->data, b->m_data);
+ }
+ b->data[ori_len] = tag[0]; b->data[ori_len + 1] = tag[1];
+ b->data[ori_len + 2] = type;
+ memcpy(b->data + ori_len + 3, data, len);
+}
+
+static inline uint8_t *skip_aux(uint8_t *s)
+{
+ int size = aux_type2size(*s); ++s; // skip type
+ uint32_t n;
+ switch (size) {
+ case 'Z':
+ case 'H':
+ while (*s) ++s;
+ return s + 1;
+ case 'B':
+ size = aux_type2size(*s); ++s;
+ memcpy(&n, s, 4); s += 4;
+ return s + size * n;
+ case 0:
+ abort();
+ break;
+ default:
+ return s + size;
+ }
+}
+
+uint8_t *bam_aux_get(const bam1_t *b, const char tag[2])
+{
+ uint8_t *s;
+ int y = tag[0]<<8 | tag[1];
+ s = bam_get_aux(b);
+ while (s < b->data + b->l_data) {
+ int x = (int)s[0]<<8 | s[1];
+ s += 2;
+ if (x == y) return s;
+ s = skip_aux(s);
+ }
+ return 0;
+}
+// s MUST BE returned by bam_aux_get()
+int bam_aux_del(bam1_t *b, uint8_t *s)
+{
+ uint8_t *p, *aux;
+ int l_aux = bam_get_l_aux(b);
+ aux = bam_get_aux(b);
+ p = s - 2;
+ s = skip_aux(s);
+ memmove(p, s, l_aux - (s - aux));
+ b->l_data -= s - p;
+ return 0;
+}
+
+int32_t bam_aux2i(const uint8_t *s)
+{
+ int type;
+ type = *s++;
+ if (type == 'c') return (int32_t)*(int8_t*)s;
+ else if (type == 'C') return (int32_t)*(uint8_t*)s;
+ else if (type == 's') return (int32_t)*(int16_t*)s;
+ else if (type == 'S') return (int32_t)*(uint16_t*)s;
+ else if (type == 'i' || type == 'I') return *(int32_t*)s;
+ else return 0;
+}
+
+double bam_aux2f(const uint8_t *s)
+{
+ int type;
+ type = *s++;
+ if (type == 'd') return *(double*)s;
+ else if (type == 'f') return *(float*)s;
+ else return 0.0;
+}
+
+char bam_aux2A(const uint8_t *s)
+{
+ int type;
+ type = *s++;
+ if (type == 'A') return *(char*)s;
+ else return 0;
+}
+
+char *bam_aux2Z(const uint8_t *s)
+{
+ int type;
+ type = *s++;
+ if (type == 'Z' || type == 'H') return (char*)s;
+ else return 0;
+}
+
+int sam_open_mode(char *mode, const char *fn, const char *format)
+{
+ // TODO Parse "bam5" etc for compression level
+ if (format == NULL) {
+ // Try to pick a format based on the filename extension
+ const char *ext = fn? strrchr(fn, '.') : NULL;
+ if (ext == NULL || strchr(ext, '/')) return -1;
+ return sam_open_mode(mode, fn, ext+1);
+ }
+ else if (strcmp(format, "bam") == 0) strcpy(mode, "b");
+ else if (strcmp(format, "cram") == 0) strcpy(mode, "c");
+ else if (strcmp(format, "sam") == 0) strcpy(mode, "");
+ else return -1;
+
+ return 0;
+}
+
+// A version of sam_open_mode that can handle ,key=value options.
+// The format string is allocated and returned, to be freed by the caller.
+// Prefix should be "r" or "w",
+char *sam_open_mode_opts(const char *fn,
+ const char *mode,
+ const char *format)
+{
+ char *mode_opts = malloc((format ? strlen(format) : 1) +
+ (mode ? strlen(mode) : 1) + 12);
+ char *opts, *cp;
+ int format_len;
+
+ if (!mode_opts)
+ return NULL;
+
+ strcpy(mode_opts, mode ? mode : "r");
+ cp = mode_opts + strlen(mode_opts);
+
+ if (format == NULL) {
+ // Try to pick a format based on the filename extension
+ const char *ext = fn? strrchr(fn, '.') : NULL;
+ if (ext == NULL || strchr(ext, '/')) {
+ free(mode_opts);
+ return NULL;
+ }
+ return sam_open_mode(cp, fn, ext+1)
+ ? (free(mode_opts), NULL)
+ : mode_opts;
+ }
+
+ if ((opts = strchr(format, ','))) {
+ format_len = opts-format;
+ } else {
+ opts="";
+ format_len = strlen(format);
+ }
+
+ if (strncmp(format, "bam", format_len) == 0) {
+ *cp++ = 'b';
+ } else if (strncmp(format, "cram", format_len) == 0) {
+ *cp++ = 'c';
+ } else if (strncmp(format, "cram2", format_len) == 0) {
+ *cp++ = 'c';
+ strcpy(cp, ",VERSION=2.1");
+ cp += 12;
+ } else if (strncmp(format, "cram3", format_len) == 0) {
+ *cp++ = 'c';
+ strcpy(cp, ",VERSION=3.0");
+ cp += 12;
+ } else if (strncmp(format, "sam", format_len) == 0) {
+ ; // format mode=""
+ } else {
+ free(mode_opts);
+ return NULL;
+ }
+
+ strcpy(cp, opts);
+
+ return mode_opts;
+}
+
+#define STRNCMP(a,b,n) (strncasecmp((a),(b),(n)) || strlen(a)!=(n))
+int bam_str2flag(const char *str)
+{
+ char *end, *beg = (char*) str;
+ long int flag = strtol(str, &end, 0);
+ if ( end!=str ) return flag; // the conversion was successful
+ flag = 0;
+ while ( *str )
+ {
+ end = beg;
+ while ( *end && *end!=',' ) end++;
+ if ( !STRNCMP("PAIRED",beg,end-beg) ) flag |= BAM_FPAIRED;
+ else if ( !STRNCMP("PROPER_PAIR",beg,end-beg) ) flag |= BAM_FPROPER_PAIR;
+ else if ( !STRNCMP("UNMAP",beg,end-beg) ) flag |= BAM_FUNMAP;
+ else if ( !STRNCMP("MUNMAP",beg,end-beg) ) flag |= BAM_FMUNMAP;
+ else if ( !STRNCMP("REVERSE",beg,end-beg) ) flag |= BAM_FREVERSE;
+ else if ( !STRNCMP("MREVERSE",beg,end-beg) ) flag |= BAM_FMREVERSE;
+ else if ( !STRNCMP("READ1",beg,end-beg) ) flag |= BAM_FREAD1;
+ else if ( !STRNCMP("READ2",beg,end-beg) ) flag |= BAM_FREAD2;
+ else if ( !STRNCMP("SECONDARY",beg,end-beg) ) flag |= BAM_FSECONDARY;
+ else if ( !STRNCMP("QCFAIL",beg,end-beg) ) flag |= BAM_FQCFAIL;
+ else if ( !STRNCMP("DUP",beg,end-beg) ) flag |= BAM_FDUP;
+ else if ( !STRNCMP("SUPPLEMENTARY",beg,end-beg) ) flag |= BAM_FSUPPLEMENTARY;
+ else return -1;
+ if ( !*end ) break;
+ beg = end + 1;
+ }
+ return flag;
+}
+
+char *bam_flag2str(int flag)
+{
+ kstring_t str = {0,0,0};
+ if ( flag&BAM_FPAIRED ) ksprintf(&str,"%s%s", str.l?",":"","PAIRED");
+ if ( flag&BAM_FPROPER_PAIR ) ksprintf(&str,"%s%s", str.l?",":"","PROPER_PAIR");
+ if ( flag&BAM_FUNMAP ) ksprintf(&str,"%s%s", str.l?",":"","UNMAP");
+ if ( flag&BAM_FMUNMAP ) ksprintf(&str,"%s%s", str.l?",":"","MUNMAP");
+ if ( flag&BAM_FREVERSE ) ksprintf(&str,"%s%s", str.l?",":"","REVERSE");
+ if ( flag&BAM_FMREVERSE ) ksprintf(&str,"%s%s", str.l?",":"","MREVERSE");
+ if ( flag&BAM_FREAD1 ) ksprintf(&str,"%s%s", str.l?",":"","READ1");
+ if ( flag&BAM_FREAD2 ) ksprintf(&str,"%s%s", str.l?",":"","READ2");
+ if ( flag&BAM_FSECONDARY ) ksprintf(&str,"%s%s", str.l?",":"","SECONDARY");
+ if ( flag&BAM_FQCFAIL ) ksprintf(&str,"%s%s", str.l?",":"","QCFAIL");
+ if ( flag&BAM_FDUP ) ksprintf(&str,"%s%s", str.l?",":"","DUP");
+ if ( flag&BAM_FSUPPLEMENTARY ) ksprintf(&str,"%s%s", str.l?",":"","SUPPLEMENTARY");
+ if ( str.l == 0 ) kputsn("", 0, &str);
+ return str.s;
+}
+
+
+/**************************
+ *** Pileup and Mpileup ***
+ **************************/
+
+#if !defined(BAM_NO_PILEUP)
+
+#include <assert.h>
+
+/*******************
+ *** Memory pool ***
+ *******************/
+
+typedef struct {
+ int k, x, y, end;
+} cstate_t;
+
+static cstate_t g_cstate_null = { -1, 0, 0, 0 };
+
+typedef struct __linkbuf_t {
+ bam1_t b;
+ int32_t beg, end;
+ cstate_t s;
+ struct __linkbuf_t *next;
+} lbnode_t;
+
+typedef struct {
+ int cnt, n, max;
+ lbnode_t **buf;
+} mempool_t;
+
+static mempool_t *mp_init(void)
+{
+ mempool_t *mp;
+ mp = (mempool_t*)calloc(1, sizeof(mempool_t));
+ return mp;
+}
+static void mp_destroy(mempool_t *mp)
+{
+ int k;
+ for (k = 0; k < mp->n; ++k) {
+ free(mp->buf[k]->b.data);
+ free(mp->buf[k]);
+ }
+ free(mp->buf);
+ free(mp);
+}
+static inline lbnode_t *mp_alloc(mempool_t *mp)
+{
+ ++mp->cnt;
+ if (mp->n == 0) return (lbnode_t*)calloc(1, sizeof(lbnode_t));
+ else return mp->buf[--mp->n];
+}
+static inline void mp_free(mempool_t *mp, lbnode_t *p)
+{
+ --mp->cnt; p->next = 0; // clear lbnode_t::next here
+ if (mp->n == mp->max) {
+ mp->max = mp->max? mp->max<<1 : 256;
+ mp->buf = (lbnode_t**)realloc(mp->buf, sizeof(lbnode_t*) * mp->max);
+ }
+ mp->buf[mp->n++] = p;
+}
+
+/**********************
+ *** CIGAR resolver ***
+ **********************/
+
+/* s->k: the index of the CIGAR operator that has just been processed.
+ s->x: the reference coordinate of the start of s->k
+ s->y: the query coordiante of the start of s->k
+ */
+static inline int resolve_cigar2(bam_pileup1_t *p, int32_t pos, cstate_t *s)
+{
+#define _cop(c) ((c)&BAM_CIGAR_MASK)
+#define _cln(c) ((c)>>BAM_CIGAR_SHIFT)
+
+ bam1_t *b = p->b;
+ bam1_core_t *c = &b->core;
+ uint32_t *cigar = bam_get_cigar(b);
+ int k;
+ // determine the current CIGAR operation
+// fprintf(stderr, "%s\tpos=%d\tend=%d\t(%d,%d,%d)\n", bam_get_qname(b), pos, s->end, s->k, s->x, s->y);
+ if (s->k == -1) { // never processed
+ if (c->n_cigar == 1) { // just one operation, save a loop
+ if (_cop(cigar[0]) == BAM_CMATCH || _cop(cigar[0]) == BAM_CEQUAL || _cop(cigar[0]) == BAM_CDIFF) s->k = 0, s->x = c->pos, s->y = 0;
+ } else { // find the first match or deletion
+ for (k = 0, s->x = c->pos, s->y = 0; k < c->n_cigar; ++k) {
+ int op = _cop(cigar[k]);
+ int l = _cln(cigar[k]);
+ if (op == BAM_CMATCH || op == BAM_CDEL || op == BAM_CEQUAL || op == BAM_CDIFF) break;
+ else if (op == BAM_CREF_SKIP) s->x += l;
+ else if (op == BAM_CINS || op == BAM_CSOFT_CLIP) s->y += l;
+ }
+ assert(k < c->n_cigar);
+ s->k = k;
+ }
+ } else { // the read has been processed before
+ int op, l = _cln(cigar[s->k]);
+ if (pos - s->x >= l) { // jump to the next operation
+ assert(s->k < c->n_cigar); // otherwise a bug: this function should not be called in this case
+ op = _cop(cigar[s->k+1]);
+ if (op == BAM_CMATCH || op == BAM_CDEL || op == BAM_CREF_SKIP || op == BAM_CEQUAL || op == BAM_CDIFF) { // jump to the next without a loop
+ if (_cop(cigar[s->k]) == BAM_CMATCH|| _cop(cigar[s->k]) == BAM_CEQUAL || _cop(cigar[s->k]) == BAM_CDIFF) s->y += l;
+ s->x += l;
+ ++s->k;
+ } else { // find the next M/D/N/=/X
+ if (_cop(cigar[s->k]) == BAM_CMATCH|| _cop(cigar[s->k]) == BAM_CEQUAL || _cop(cigar[s->k]) == BAM_CDIFF) s->y += l;
+ s->x += l;
+ for (k = s->k + 1; k < c->n_cigar; ++k) {
+ op = _cop(cigar[k]), l = _cln(cigar[k]);
+ if (op == BAM_CMATCH || op == BAM_CDEL || op == BAM_CREF_SKIP || op == BAM_CEQUAL || op == BAM_CDIFF) break;
+ else if (op == BAM_CINS || op == BAM_CSOFT_CLIP) s->y += l;
+ }
+ s->k = k;
+ }
+ assert(s->k < c->n_cigar); // otherwise a bug
+ } // else, do nothing
+ }
+ { // collect pileup information
+ int op, l;
+ op = _cop(cigar[s->k]); l = _cln(cigar[s->k]);
+ p->is_del = p->indel = p->is_refskip = 0;
+ if (s->x + l - 1 == pos && s->k + 1 < c->n_cigar) { // peek the next operation
+ int op2 = _cop(cigar[s->k+1]);
+ int l2 = _cln(cigar[s->k+1]);
+ if (op2 == BAM_CDEL) p->indel = -(int)l2;
+ else if (op2 == BAM_CINS) p->indel = l2;
+ else if (op2 == BAM_CPAD && s->k + 2 < c->n_cigar) { // no working for adjacent padding
+ int l3 = 0;
+ for (k = s->k + 2; k < c->n_cigar; ++k) {
+ op2 = _cop(cigar[k]); l2 = _cln(cigar[k]);
+ if (op2 == BAM_CINS) l3 += l2;
+ else if (op2 == BAM_CDEL || op2 == BAM_CMATCH || op2 == BAM_CREF_SKIP || op2 == BAM_CEQUAL || op2 == BAM_CDIFF) break;
+ }
+ if (l3 > 0) p->indel = l3;
+ }
+ }
+ if (op == BAM_CMATCH || op == BAM_CEQUAL || op == BAM_CDIFF) {
+ p->qpos = s->y + (pos - s->x);
+ } else if (op == BAM_CDEL || op == BAM_CREF_SKIP) {
+ p->is_del = 1; p->qpos = s->y; // FIXME: distinguish D and N!!!!!
+ p->is_refskip = (op == BAM_CREF_SKIP);
+ } // cannot be other operations; otherwise a bug
+ p->is_head = (pos == c->pos); p->is_tail = (pos == s->end);
+ }
+ return 1;
+}
+
+/***********************
+ *** Pileup iterator ***
+ ***********************/
+
+// Dictionary of overlapping reads
+KHASH_MAP_INIT_STR(olap_hash, lbnode_t *)
+typedef khash_t(olap_hash) olap_hash_t;
+
+struct __bam_plp_t {
+ mempool_t *mp;
+ lbnode_t *head, *tail;
+ int32_t tid, pos, max_tid, max_pos;
+ int is_eof, max_plp, error, maxcnt;
+ uint64_t id;
+ bam_pileup1_t *plp;
+ // for the "auto" interface only
+ bam1_t *b;
+ bam_plp_auto_f func;
+ void *data;
+ olap_hash_t *overlaps;
+};
+
+bam_plp_t bam_plp_init(bam_plp_auto_f func, void *data)
+{
+ bam_plp_t iter;
+ iter = (bam_plp_t)calloc(1, sizeof(struct __bam_plp_t));
+ iter->mp = mp_init();
+ iter->head = iter->tail = mp_alloc(iter->mp);
+ iter->max_tid = iter->max_pos = -1;
+ iter->maxcnt = 8000;
+ if (func) {
+ iter->func = func;
+ iter->data = data;
+ iter->b = bam_init1();
+ }
+ return iter;
+}
+
+void bam_plp_init_overlaps(bam_plp_t iter)
+{
+ iter->overlaps = kh_init(olap_hash); // hash for tweaking quality of bases in overlapping reads
+}
+
+void bam_plp_destroy(bam_plp_t iter)
+{
+ lbnode_t *p, *pnext;
+ if ( iter->overlaps ) kh_destroy(olap_hash, iter->overlaps);
+ for (p = iter->head; p != NULL; p = pnext) {
+ pnext = p->next;
+ mp_free(iter->mp, p);
+ }
+ mp_destroy(iter->mp);
+ if (iter->b) bam_destroy1(iter->b);
+ free(iter->plp);
+ free(iter);
+}
+
+
+//---------------------------------
+//--- Tweak overlapping reads
+//---------------------------------
+
+/**
+ * cigar_iref2iseq_set() - find the first CMATCH setting the ref and the read index
+ * cigar_iref2iseq_next() - get the next CMATCH base
+ * @cigar: pointer to current cigar block (rw)
+ * @cigar_max: pointer just beyond the last cigar block
+ * @icig: position within the current cigar block (rw)
+ * @iseq: position in the sequence (rw)
+ * @iref: position with respect to the beginning of the read (iref_pos - b->core.pos) (rw)
+ *
+ * Returns BAM_CMATCH or -1 when there is no more cigar to process or the requested position is not covered.
+ */
+static inline int cigar_iref2iseq_set(uint32_t **cigar, uint32_t *cigar_max, int *icig, int *iseq, int *iref)
+{
+ int pos = *iref;
+ if ( pos < 0 ) return -1;
+ *icig = 0;
+ *iseq = 0;
+ *iref = 0;
+ while ( *cigar<cigar_max )
+ {
+ int cig = (**cigar) & BAM_CIGAR_MASK;
+ int ncig = (**cigar) >> BAM_CIGAR_SHIFT;
+
+ if ( cig==BAM_CSOFT_CLIP ) { (*cigar)++; *iseq += ncig; *icig = 0; continue; }
+ if ( cig==BAM_CHARD_CLIP || cig==BAM_CPAD ) { (*cigar)++; *icig = 0; continue; }
+ if ( cig==BAM_CMATCH || cig==BAM_CEQUAL || cig==BAM_CDIFF )
+ {
+ pos -= ncig;
+ if ( pos < 0 ) { *icig = ncig + pos; *iseq += *icig; *iref += *icig; return BAM_CMATCH; }
+ (*cigar)++; *iseq += ncig; *icig = 0; *iref += ncig;
+ continue;
+ }
+ if ( cig==BAM_CINS ) { (*cigar)++; *iseq += ncig; *icig = 0; continue; }
+ if ( cig==BAM_CDEL || cig==BAM_CREF_SKIP )
+ {
+ pos -= ncig;
+ if ( pos<0 ) pos = 0;
+ (*cigar)++; *icig = 0; *iref += ncig;
+ continue;
+ }
+ fprintf(stderr,"todo: cigar %d\n", cig);
+ assert(0);
+ }
+ *iseq = -1;
+ return -1;
+}
+static inline int cigar_iref2iseq_next(uint32_t **cigar, uint32_t *cigar_max, int *icig, int *iseq, int *iref)
+{
+ while ( *cigar < cigar_max )
+ {
+ int cig = (**cigar) & BAM_CIGAR_MASK;
+ int ncig = (**cigar) >> BAM_CIGAR_SHIFT;
+
+ if ( cig==BAM_CMATCH || cig==BAM_CEQUAL || cig==BAM_CDIFF )
+ {
+ if ( *icig >= ncig - 1 ) { *icig = 0; (*cigar)++; continue; }
+ (*iseq)++; (*icig)++; (*iref)++;
+ return BAM_CMATCH;
+ }
+ if ( cig==BAM_CDEL || cig==BAM_CREF_SKIP ) { (*cigar)++; (*iref) += ncig; *icig = 0; continue; }
+ if ( cig==BAM_CINS ) { (*cigar)++; *iseq += ncig; *icig = 0; continue; }
+ if ( cig==BAM_CSOFT_CLIP ) { (*cigar)++; *iseq += ncig; *icig = 0; continue; }
+ if ( cig==BAM_CHARD_CLIP || cig==BAM_CPAD ) { (*cigar)++; *icig = 0; continue; }
+ fprintf(stderr,"todo: cigar %d\n", cig);
+ assert(0);
+ }
+ *iseq = -1;
+ *iref = -1;
+ return -1;
+}
+
+static void tweak_overlap_quality(bam1_t *a, bam1_t *b)
+{
+ uint32_t *a_cigar = bam_get_cigar(a), *a_cigar_max = a_cigar + a->core.n_cigar;
+ uint32_t *b_cigar = bam_get_cigar(b), *b_cigar_max = b_cigar + b->core.n_cigar;
+ int a_icig = 0, a_iseq = 0;
+ int b_icig = 0, b_iseq = 0;
+ uint8_t *a_qual = bam_get_qual(a), *b_qual = bam_get_qual(b);
+ uint8_t *a_seq = bam_get_seq(a), *b_seq = bam_get_seq(b);
+
+ int iref = b->core.pos;
+ int a_iref = iref - a->core.pos;
+ int b_iref = iref - b->core.pos;
+ int a_ret = cigar_iref2iseq_set(&a_cigar, a_cigar_max, &a_icig, &a_iseq, &a_iref);
+ if ( a_ret<0 ) return; // no overlap
+ int b_ret = cigar_iref2iseq_set(&b_cigar, b_cigar_max, &b_icig, &b_iseq, &b_iref);
+ if ( b_ret<0 ) return; // no overlap
+
+ #if DBG
+ fprintf(stderr,"tweak %s n_cigar=%d %d .. %d-%d vs %d-%d\n", bam_get_qname(a), a->core.n_cigar, b->core.n_cigar,
+ a->core.pos+1,a->core.pos+bam_cigar2rlen(a->core.n_cigar,bam_get_cigar(a)), b->core.pos+1, b->core.pos+bam_cigar2rlen(b->core.n_cigar,bam_get_cigar(b)));
+ #endif
+
+ while ( 1 )
+ {
+ // Increment reference position
+ while ( a_iref>=0 && a_iref < iref - a->core.pos )
+ a_ret = cigar_iref2iseq_next(&a_cigar, a_cigar_max, &a_icig, &a_iseq, &a_iref);
+ if ( a_ret<0 ) break; // done
+ if ( iref < a_iref + a->core.pos ) iref = a_iref + a->core.pos;
+
+ while ( b_iref>=0 && b_iref < iref - b->core.pos )
+ b_ret = cigar_iref2iseq_next(&b_cigar, b_cigar_max, &b_icig, &b_iseq, &b_iref);
+ if ( b_ret<0 ) break; // done
+ if ( iref < b_iref + b->core.pos ) iref = b_iref + b->core.pos;
+
+ iref++;
+ if ( a_iref+a->core.pos != b_iref+b->core.pos ) continue; // only CMATCH positions, don't know what to do with indels
+
+ if ( bam_seqi(a_seq,a_iseq) == bam_seqi(b_seq,b_iseq) )
+ {
+ #if DBG
+ fprintf(stderr,"%c",seq_nt16_str[bam_seqi(a_seq,a_iseq)]);
+ #endif
+ // we are very confident about this base
+ int qual = a_qual[a_iseq] + b_qual[b_iseq];
+ a_qual[a_iseq] = qual>200 ? 200 : qual;
+ b_qual[b_iseq] = 0;
+ }
+ else
+ {
+ if ( a_qual[a_iseq] >= b_qual[b_iseq] )
+ {
+ #if DBG
+ fprintf(stderr,"[%c/%c]",seq_nt16_str[bam_seqi(a_seq,a_iseq)],tolower(seq_nt16_str[bam_seqi(b_seq,b_iseq)]));
+ #endif
+ a_qual[a_iseq] = 0.8 * a_qual[a_iseq]; // not so confident about a_qual anymore given the mismatch
+ b_qual[b_iseq] = 0;
+ }
+ else
+ {
+ #if DBG
+ fprintf(stderr,"[%c/%c]",tolower(seq_nt16_str[bam_seqi(a_seq,a_iseq)]),seq_nt16_str[bam_seqi(b_seq,b_iseq)]);
+ #endif
+ b_qual[b_iseq] = 0.8 * b_qual[b_iseq];
+ a_qual[a_iseq] = 0;
+ }
+ }
+ }
+ #if DBG
+ fprintf(stderr,"\n");
+ #endif
+}
+
+// Fix overlapping reads. Simple soft-clipping did not give good results.
+// Lowering qualities of unwanted bases is more selective and works better.
+//
+static void overlap_push(bam_plp_t iter, lbnode_t *node)
+{
+ if ( !iter->overlaps ) return;
+
+ // mapped mates and paired reads only
+ if ( node->b.core.flag&BAM_FMUNMAP || !(node->b.core.flag&BAM_FPROPER_PAIR) ) return;
+
+ // no overlap possible, unless some wild cigar
+ if ( abs(node->b.core.isize) >= 2*node->b.core.l_qseq ) return;
+
+ khiter_t kitr = kh_get(olap_hash, iter->overlaps, bam_get_qname(&node->b));
+ if ( kitr==kh_end(iter->overlaps) )
+ {
+ int ret;
+ kitr = kh_put(olap_hash, iter->overlaps, bam_get_qname(&node->b), &ret);
+ kh_value(iter->overlaps, kitr) = node;
+ }
+ else
+ {
+ lbnode_t *a = kh_value(iter->overlaps, kitr);
+ tweak_overlap_quality(&a->b, &node->b);
+ kh_del(olap_hash, iter->overlaps, kitr);
+ assert(a->end-1 == a->s.end);
+ a->end = bam_endpos(&a->b);
+ a->s.end = a->end - 1;
+ }
+}
+
+static void overlap_remove(bam_plp_t iter, const bam1_t *b)
+{
+ if ( !iter->overlaps ) return;
+
+ khiter_t kitr;
+ if ( b )
+ {
+ kitr = kh_get(olap_hash, iter->overlaps, bam_get_qname(b));
+ if ( kitr!=kh_end(iter->overlaps) )
+ kh_del(olap_hash, iter->overlaps, kitr);
+ }
+ else
+ {
+ // remove all
+ for (kitr = kh_begin(iter->overlaps); kitr<kh_end(iter->overlaps); kitr++)
+ if ( kh_exist(iter->overlaps, kitr) ) kh_del(olap_hash, iter->overlaps, kitr);
+ }
+}
+
+
+
+// Prepares next pileup position in bam records collected by bam_plp_auto -> user func -> bam_plp_push. Returns
+// pointer to the piled records if next position is ready or NULL if there is not enough records in the
+// buffer yet (the current position is still the maximum position across all buffered reads).
+const bam_pileup1_t *bam_plp_next(bam_plp_t iter, int *_tid, int *_pos, int *_n_plp)
+{
+ if (iter->error) { *_n_plp = -1; return 0; }
+ *_n_plp = 0;
+ if (iter->is_eof && iter->head == iter->tail) return 0;
+ while (iter->is_eof || iter->max_tid > iter->tid || (iter->max_tid == iter->tid && iter->max_pos > iter->pos)) {
+ int n_plp = 0;
+ // write iter->plp at iter->pos
+ lbnode_t **pptr = &iter->head;
+ while (*pptr != iter->tail) {
+ lbnode_t *p = *pptr;
+ if (p->b.core.tid < iter->tid || (p->b.core.tid == iter->tid && p->end <= iter->pos)) { // then remove
+ overlap_remove(iter, &p->b);
+ *pptr = p->next; mp_free(iter->mp, p);
+ }
+ else {
+ if (p->b.core.tid == iter->tid && p->beg <= iter->pos) { // here: p->end > pos; then add to pileup
+ if (n_plp == iter->max_plp) { // then double the capacity
+ iter->max_plp = iter->max_plp? iter->max_plp<<1 : 256;
+ iter->plp = (bam_pileup1_t*)realloc(iter->plp, sizeof(bam_pileup1_t) * iter->max_plp);
+ }
+ iter->plp[n_plp].b = &p->b;
+ if (resolve_cigar2(iter->plp + n_plp, iter->pos, &p->s)) ++n_plp; // actually always true...
+ }
+ pptr = &(*pptr)->next;
+ }
+ }
+ *_n_plp = n_plp; *_tid = iter->tid; *_pos = iter->pos;
+ // update iter->tid and iter->pos
+ if (iter->head != iter->tail) {
+ if (iter->tid > iter->head->b.core.tid) {
+ fprintf(stderr, "[%s] unsorted input. Pileup aborts.\n", __func__);
+ iter->error = 1;
+ *_n_plp = -1;
+ return 0;
+ }
+ }
+ if (iter->tid < iter->head->b.core.tid) { // come to a new reference sequence
+ iter->tid = iter->head->b.core.tid; iter->pos = iter->head->beg; // jump to the next reference
+ } else if (iter->pos < iter->head->beg) { // here: tid == head->b.core.tid
+ iter->pos = iter->head->beg; // jump to the next position
+ } else ++iter->pos; // scan contiguously
+ // return
+ if (n_plp) return iter->plp;
+ if (iter->is_eof && iter->head == iter->tail) break;
+ }
+ return 0;
+}
+
+int bam_plp_push(bam_plp_t iter, const bam1_t *b)
+{
+ if (iter->error) return -1;
+ if (b) {
+ if (b->core.tid < 0) { overlap_remove(iter, b); return 0; }
+ // Skip only unmapped reads here, any additional filtering must be done in iter->func
+ if (b->core.flag & BAM_FUNMAP) { overlap_remove(iter, b); return 0; }
+ if (iter->tid == b->core.tid && iter->pos == b->core.pos && iter->mp->cnt > iter->maxcnt)
+ {
+ overlap_remove(iter, b);
+ return 0;
+ }
+ bam_copy1(&iter->tail->b, b);
+ overlap_push(iter, iter->tail);
+#ifndef BAM_NO_ID
+ iter->tail->b.id = iter->id++;
+#endif
+ iter->tail->beg = b->core.pos;
+ iter->tail->end = bam_endpos(b);
+ iter->tail->s = g_cstate_null; iter->tail->s.end = iter->tail->end - 1; // initialize cstate_t
+ if (b->core.tid < iter->max_tid) {
+ fprintf(stderr, "[bam_pileup_core] the input is not sorted (chromosomes out of order)\n");
+ iter->error = 1;
+ return -1;
+ }
+ if ((b->core.tid == iter->max_tid) && (iter->tail->beg < iter->max_pos)) {
+ fprintf(stderr, "[bam_pileup_core] the input is not sorted (reads out of order)\n");
+ iter->error = 1;
+ return -1;
+ }
+ iter->max_tid = b->core.tid; iter->max_pos = iter->tail->beg;
+ if (iter->tail->end > iter->pos || iter->tail->b.core.tid > iter->tid) {
+ iter->tail->next = mp_alloc(iter->mp);
+ iter->tail = iter->tail->next;
+ }
+ } else iter->is_eof = 1;
+ return 0;
+}
+
+const bam_pileup1_t *bam_plp_auto(bam_plp_t iter, int *_tid, int *_pos, int *_n_plp)
+{
+ const bam_pileup1_t *plp;
+ if (iter->func == 0 || iter->error) { *_n_plp = -1; return 0; }
+ if ((plp = bam_plp_next(iter, _tid, _pos, _n_plp)) != 0) return plp;
+ else { // no pileup line can be obtained; read alignments
+ *_n_plp = 0;
+ if (iter->is_eof) return 0;
+ int ret;
+ while ( (ret=iter->func(iter->data, iter->b)) >= 0) {
+ if (bam_plp_push(iter, iter->b) < 0) {
+ *_n_plp = -1;
+ return 0;
+ }
+ if ((plp = bam_plp_next(iter, _tid, _pos, _n_plp)) != 0) return plp;
+ // otherwise no pileup line can be returned; read the next alignment.
+ }
+ if ( ret < -1 ) { iter->error = ret; *_n_plp = -1; return 0; }
+ bam_plp_push(iter, 0);
+ if ((plp = bam_plp_next(iter, _tid, _pos, _n_plp)) != 0) return plp;
+ return 0;
+ }
+}
+
+void bam_plp_reset(bam_plp_t iter)
+{
+ overlap_remove(iter, NULL);
+ iter->max_tid = iter->max_pos = -1;
+ iter->tid = iter->pos = 0;
+ iter->is_eof = 0;
+ while (iter->head != iter->tail) {
+ lbnode_t *p = iter->head;
+ iter->head = p->next;
+ mp_free(iter->mp, p);
+ }
+}
+
+void bam_plp_set_maxcnt(bam_plp_t iter, int maxcnt)
+{
+ iter->maxcnt = maxcnt;
+}
+
+/************************
+ *** Mpileup iterator ***
+ ************************/
+
+struct __bam_mplp_t {
+ int n;
+ uint64_t min, *pos;
+ bam_plp_t *iter;
+ int *n_plp;
+ const bam_pileup1_t **plp;
+};
+
+bam_mplp_t bam_mplp_init(int n, bam_plp_auto_f func, void **data)
+{
+ int i;
+ bam_mplp_t iter;
+ iter = (bam_mplp_t)calloc(1, sizeof(struct __bam_mplp_t));
+ iter->pos = (uint64_t*)calloc(n, sizeof(uint64_t));
+ iter->n_plp = (int*)calloc(n, sizeof(int));
+ iter->plp = (const bam_pileup1_t**)calloc(n, sizeof(bam_pileup1_t*));
+ iter->iter = (bam_plp_t*)calloc(n, sizeof(bam_plp_t));
+ iter->n = n;
+ iter->min = (uint64_t)-1;
+ for (i = 0; i < n; ++i) {
+ iter->iter[i] = bam_plp_init(func, data[i]);
+ iter->pos[i] = iter->min;
+ }
+ return iter;
+}
+
+void bam_mplp_init_overlaps(bam_mplp_t iter)
+{
+ int i;
+ for (i = 0; i < iter->n; ++i)
+ bam_plp_init_overlaps(iter->iter[i]);
+}
+
+void bam_mplp_set_maxcnt(bam_mplp_t iter, int maxcnt)
+{
+ int i;
+ for (i = 0; i < iter->n; ++i)
+ iter->iter[i]->maxcnt = maxcnt;
+}
+
+void bam_mplp_destroy(bam_mplp_t iter)
+{
+ int i;
+ for (i = 0; i < iter->n; ++i) bam_plp_destroy(iter->iter[i]);
+ free(iter->iter); free(iter->pos); free(iter->n_plp); free(iter->plp);
+ free(iter);
+}
+
+int bam_mplp_auto(bam_mplp_t iter, int *_tid, int *_pos, int *n_plp, const bam_pileup1_t **plp)
+{
+ int i, ret = 0;
+ uint64_t new_min = (uint64_t)-1;
+ for (i = 0; i < iter->n; ++i) {
+ if (iter->pos[i] == iter->min) {
+ int tid, pos;
+ iter->plp[i] = bam_plp_auto(iter->iter[i], &tid, &pos, &iter->n_plp[i]);
+ if ( iter->iter[i]->error ) return -1;
+ iter->pos[i] = iter->plp[i] ? (uint64_t)tid<<32 | pos : 0;
+ }
+ if (iter->plp[i] && iter->pos[i] < new_min) new_min = iter->pos[i];
+ }
+ iter->min = new_min;
+ if (new_min == (uint64_t)-1) return 0;
+ *_tid = new_min>>32; *_pos = (uint32_t)new_min;
+ for (i = 0; i < iter->n; ++i) {
+ if (iter->pos[i] == iter->min) { // FIXME: valgrind reports "uninitialised value(s) at this line"
+ n_plp[i] = iter->n_plp[i], plp[i] = iter->plp[i];
+ ++ret;
+ } else n_plp[i] = 0, plp[i] = 0;
+ }
+ return ret;
+}
+
+#endif // ~!defined(BAM_NO_PILEUP)
--- /dev/null
+/* synced_bcf_reader.c -- stream through multiple VCF files.
+
+ Copyright (C) 2012-2014 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <unistd.h>
+#include <string.h>
+#include <limits.h>
+#include <errno.h>
+#include <ctype.h>
+#include <sys/stat.h>
+#include "htslib/synced_bcf_reader.h"
+#include "htslib/kseq.h"
+#include "htslib/khash_str2int.h"
+#include "htslib/bgzf.h"
+
+#define MAX_CSI_COOR 0x7fffffff // maximum indexable coordinate of .csi
+
+typedef struct
+{
+ uint32_t start, end;
+}
+region1_t;
+
+typedef struct _region_t
+{
+ region1_t *regs;
+ int nregs, mregs, creg;
+}
+region_t;
+
+static void _regions_add(bcf_sr_regions_t *reg, const char *chr, int start, int end);
+static bcf_sr_regions_t *_regions_init_string(const char *str);
+static int _regions_match_alleles(bcf_sr_regions_t *reg, int als_idx, bcf1_t *rec);
+
+char *bcf_sr_strerror(int errnum)
+{
+ switch (errnum)
+ {
+ case open_failed:
+ return strerror(errno); break;
+ case not_bgzf:
+ return "not compressed with bgzip"; break;
+ case idx_load_failed:
+ return "could not load index"; break;
+ case file_type_error:
+ return "unknown file type"; break;
+ case api_usage_error:
+ return "API usage error"; break;
+ case header_error:
+ return "could not parse header"; break;
+ case no_eof:
+ return "no BGZF EOF marker; file may be truncated"; break;
+ default: return "";
+ }
+}
+
+static int *init_filters(bcf_hdr_t *hdr, const char *filters, int *nfilters)
+{
+ kstring_t str = {0,0,0};
+ const char *tmp = filters, *prev = filters;
+ int nout = 0, *out = NULL;
+ while ( 1 )
+ {
+ if ( *tmp==',' || !*tmp )
+ {
+ out = (int*) realloc(out, (nout+1)*sizeof(int));
+ if ( tmp-prev==1 && *prev=='.' )
+ {
+ out[nout] = -1;
+ nout++;
+ }
+ else
+ {
+ str.l = 0;
+ kputsn(prev, tmp-prev, &str);
+ out[nout] = bcf_hdr_id2int(hdr, BCF_DT_ID, str.s);
+ if ( out[nout]>=0 ) nout++;
+ }
+ if ( !*tmp ) break;
+ prev = tmp+1;
+ }
+ tmp++;
+ }
+ if ( str.m ) free(str.s);
+ *nfilters = nout;
+ return out;
+}
+
+int bcf_sr_set_regions(bcf_srs_t *readers, const char *regions, int is_file)
+{
+ assert( !readers->regions );
+ if ( readers->nreaders )
+ {
+ fprintf(stderr,"[%s:%d %s] Error: bcf_sr_set_regions() must be called before bcf_sr_add_reader()\n", __FILE__,__LINE__,__FUNCTION__);
+ return -1;
+ }
+ readers->regions = bcf_sr_regions_init(regions,is_file,0,1,-2);
+ if ( !readers->regions ) return -1;
+ readers->explicit_regs = 1;
+ readers->require_index = 1;
+ return 0;
+}
+int bcf_sr_set_targets(bcf_srs_t *readers, const char *targets, int is_file, int alleles)
+{
+ assert( !readers->targets );
+ if ( targets[0]=='^' )
+ {
+ readers->targets_exclude = 1;
+ targets++;
+ }
+ readers->targets = bcf_sr_regions_init(targets,is_file,0,1,-2);
+ if ( !readers->targets ) return -1;
+ readers->targets_als = alleles;
+ return 0;
+}
+
+int bcf_sr_add_reader(bcf_srs_t *files, const char *fname)
+{
+ htsFile* file_ptr = hts_open(fname, "r");
+ if ( ! file_ptr ) {
+ files->errnum = open_failed;
+ return 0;
+ }
+
+ files->has_line = (int*) realloc(files->has_line, sizeof(int)*(files->nreaders+1));
+ files->has_line[files->nreaders] = 0;
+ files->readers = (bcf_sr_t*) realloc(files->readers, sizeof(bcf_sr_t)*(files->nreaders+1));
+ bcf_sr_t *reader = &files->readers[files->nreaders++];
+ memset(reader,0,sizeof(bcf_sr_t));
+
+ reader->file = file_ptr;
+
+ files->errnum = 0;
+
+ if ( reader->file->format.compression==bgzf )
+ {
+ BGZF *bgzf = hts_get_bgzfp(reader->file);
+ if ( bgzf && bgzf_check_EOF(bgzf) == 0 ) {
+ files->errnum = no_eof;
+ fprintf(stderr,"[%s] Warning: no BGZF EOF marker; file may be truncated.\n", fname);
+ }
+ }
+
+ if ( files->require_index )
+ {
+ if ( reader->file->format.format==vcf )
+ {
+ if ( reader->file->format.compression!=bgzf )
+ {
+ files->errnum = not_bgzf;
+ return 0;
+ }
+
+ reader->tbx_idx = tbx_index_load(fname);
+ if ( !reader->tbx_idx )
+ {
+ files->errnum = idx_load_failed;
+ return 0;
+ }
+
+ reader->header = bcf_hdr_read(reader->file);
+ }
+ else if ( reader->file->format.format==bcf )
+ {
+ if ( reader->file->format.compression!=bgzf )
+ {
+ files->errnum = not_bgzf;
+ return 0;
+ }
+
+ reader->header = bcf_hdr_read(reader->file);
+
+ reader->bcf_idx = bcf_index_load(fname);
+ if ( !reader->bcf_idx )
+ {
+ files->errnum = idx_load_failed;
+ return 0;
+ }
+ }
+ else
+ {
+ files->errnum = file_type_error;
+ return 0;
+ }
+ }
+ else
+ {
+ if ( reader->file->format.format==bcf || reader->file->format.format==vcf )
+ {
+ reader->header = bcf_hdr_read(reader->file);
+ }
+ else
+ {
+ files->errnum = file_type_error;
+ return 0;
+ }
+ files->streaming = 1;
+ }
+ if ( files->streaming && files->nreaders>1 )
+ {
+ files->errnum = api_usage_error;
+ fprintf(stderr,"[%s:%d %s] Error: %d readers, yet require_index not set\n", __FILE__,__LINE__,__FUNCTION__,files->nreaders);
+ return 0;
+ }
+ if ( files->streaming && files->regions )
+ {
+ files->errnum = api_usage_error;
+ fprintf(stderr,"[%s:%d %s] Error: cannot tabix-jump in streaming mode\n", __FILE__,__LINE__,__FUNCTION__);
+ return 0;
+ }
+ if ( !reader->header )
+ {
+ files->errnum = header_error;
+ return 0;
+ }
+
+ reader->fname = strdup(fname);
+ if ( files->apply_filters )
+ reader->filter_ids = init_filters(reader->header, files->apply_filters, &reader->nfilter_ids);
+
+ // Update list of chromosomes
+ if ( !files->explicit_regs && !files->streaming )
+ {
+ int n,i;
+ const char **names = reader->tbx_idx ? tbx_seqnames(reader->tbx_idx, &n) : bcf_hdr_seqnames(reader->header, &n);
+ for (i=0; i<n; i++)
+ {
+ if ( !files->regions )
+ files->regions = _regions_init_string(names[i]);
+ else
+ _regions_add(files->regions, names[i], -1, -1);
+ }
+ free(names);
+ }
+
+ return 1;
+}
+
+bcf_srs_t *bcf_sr_init(void)
+{
+ bcf_srs_t *files = (bcf_srs_t*) calloc(1,sizeof(bcf_srs_t));
+ return files;
+}
+
+static void bcf_sr_destroy1(bcf_sr_t *reader)
+{
+ free(reader->fname);
+ if ( reader->tbx_idx ) tbx_destroy(reader->tbx_idx);
+ if ( reader->bcf_idx ) hts_idx_destroy(reader->bcf_idx);
+ bcf_hdr_destroy(reader->header);
+ hts_close(reader->file);
+ if ( reader->itr ) tbx_itr_destroy(reader->itr);
+ int j;
+ for (j=0; j<reader->mbuffer; j++)
+ bcf_destroy1(reader->buffer[j]);
+ free(reader->buffer);
+ free(reader->samples);
+ free(reader->filter_ids);
+}
+void bcf_sr_destroy(bcf_srs_t *files)
+{
+ int i;
+ for (i=0; i<files->nreaders; i++)
+ bcf_sr_destroy1(&files->readers[i]);
+ free(files->has_line);
+ free(files->readers);
+ for (i=0; i<files->n_smpl; i++) free(files->samples[i]);
+ free(files->samples);
+ if (files->targets) bcf_sr_regions_destroy(files->targets);
+ if (files->regions) bcf_sr_regions_destroy(files->regions);
+ if ( files->tmps.m ) free(files->tmps.s);
+ free(files);
+}
+
+void bcf_sr_remove_reader(bcf_srs_t *files, int i)
+{
+ assert( !files->samples ); // not ready for this yet
+ bcf_sr_destroy1(&files->readers[i]);
+ if ( i+1 < files->nreaders )
+ {
+ memmove(&files->readers[i], &files->readers[i+1], (files->nreaders-i-1)*sizeof(bcf_sr_t));
+ memmove(&files->has_line[i], &files->has_line[i+1], (files->nreaders-i-1)*sizeof(int));
+ }
+ files->nreaders--;
+}
+
+
+/*
+ Removes duplicate records from the buffer. The meaning of "duplicate" is
+ controlled by the $collapse variable, which can cause that from multiple
+ <indel|snp|any> lines only the first is considered and the rest is ignored.
+ The removal is done by setting the redundant lines' positions to -1 and
+ moving these lines at the end of the buffer.
+ */
+static void collapse_buffer(bcf_srs_t *files, bcf_sr_t *reader)
+{
+ int irec,jrec, has_snp=0, has_indel=0, has_any=0;
+ for (irec=1; irec<=reader->nbuffer; irec++)
+ {
+ bcf1_t *line = reader->buffer[irec];
+ if ( line->pos != reader->buffer[1]->pos ) break;
+ if ( files->collapse&COLLAPSE_ANY )
+ {
+ if ( !has_any ) has_any = 1;
+ else line->pos = -1;
+ }
+ int line_type = bcf_get_variant_types(line);
+ if ( files->collapse&COLLAPSE_SNPS && line_type&(VCF_SNP|VCF_MNP) )
+ {
+ if ( !has_snp ) has_snp = 1;
+ else line->pos = -1;
+ }
+ if ( files->collapse&COLLAPSE_INDELS && line_type&VCF_INDEL )
+ {
+ if ( !has_indel ) has_indel = 1;
+ else line->pos = -1;
+ }
+ }
+ bcf1_t *tmp;
+ irec = jrec = 1;
+ while ( irec<=reader->nbuffer && jrec<=reader->nbuffer )
+ {
+ if ( reader->buffer[irec]->pos != -1 ) { irec++; continue; }
+ if ( jrec<=irec ) jrec = irec+1;
+ while ( jrec<=reader->nbuffer && reader->buffer[jrec]->pos==-1 ) jrec++;
+ if ( jrec<=reader->nbuffer )
+ {
+ tmp = reader->buffer[irec]; reader->buffer[irec] = reader->buffer[jrec]; reader->buffer[jrec] = tmp;
+ }
+ }
+ reader->nbuffer = irec - 1;
+}
+
+void debug_buffer(FILE *fp, bcf_sr_t *reader)
+{
+ int j;
+ for (j=0; j<=reader->nbuffer; j++)
+ {
+ bcf1_t *line = reader->buffer[j];
+ fprintf(fp,"\t%p\t%s%s\t%s:%d\t%s ", line,reader->fname,j==0?"*":" ",reader->header->id[BCF_DT_CTG][line->rid].key,line->pos+1,line->n_allele?line->d.allele[0]:"");
+ int k;
+ for (k=1; k<line->n_allele; k++) fprintf(fp," %s", line->d.allele[k]);
+ fprintf(fp,"\n");
+ }
+}
+
+void debug_buffers(FILE *fp, bcf_srs_t *files)
+{
+ int i;
+ for (i=0; i<files->nreaders; i++)
+ {
+ fprintf(fp, "has_line: %d\t%s\n", bcf_sr_has_line(files,i),files->readers[i].fname);
+ debug_buffer(fp, &files->readers[i]);
+ }
+ fprintf(fp,"\n");
+}
+
+static inline int has_filter(bcf_sr_t *reader, bcf1_t *line)
+{
+ int i, j;
+ if ( !line->d.n_flt )
+ {
+ for (j=0; j<reader->nfilter_ids; j++)
+ if ( reader->filter_ids[j]<0 ) return 1;
+ return 0;
+ }
+ for (i=0; i<line->d.n_flt; i++)
+ {
+ for (j=0; j<reader->nfilter_ids; j++)
+ if ( line->d.flt[i]==reader->filter_ids[j] ) return 1;
+ }
+ return 0;
+}
+
+static int _reader_seek(bcf_sr_t *reader, const char *seq, int start, int end)
+{
+ if ( end>=MAX_CSI_COOR )
+ {
+ fprintf(stderr,"The coordinate is out of csi index limit: %d\n", end+1);
+ exit(1);
+ }
+ if ( reader->itr )
+ {
+ hts_itr_destroy(reader->itr);
+ reader->itr = NULL;
+ }
+ reader->nbuffer = 0;
+ if ( reader->tbx_idx )
+ {
+ int tid = tbx_name2id(reader->tbx_idx, seq);
+ if ( tid==-1 ) return -1; // the sequence not present in this file
+ reader->itr = tbx_itr_queryi(reader->tbx_idx,tid,start,end+1);
+ }
+ else
+ {
+ int tid = bcf_hdr_name2id(reader->header, seq);
+ if ( tid==-1 ) return -1; // the sequence not present in this file
+ reader->itr = bcf_itr_queryi(reader->bcf_idx,tid,start,end+1);
+ }
+ if ( !reader->itr ) fprintf(stderr,"Could not seek: %s:%d-%d\n",seq,start+1,end+1);
+ assert(reader->itr);
+ return 0;
+}
+
+/*
+ * _readers_next_region() - jumps to next region if necessary
+ * Returns 0 on success or -1 when there are no more regions left
+ */
+static int _readers_next_region(bcf_srs_t *files)
+{
+ // Need to open new chromosome? Check number of lines in all readers' buffers
+ int i, eos = 0;
+ for (i=0; i<files->nreaders; i++)
+ if ( !files->readers[i].itr && !files->readers[i].nbuffer ) eos++;
+
+ if ( eos!=files->nreaders )
+ {
+ // Some of the readers still has buffered lines
+ return 0;
+ }
+
+ // No lines in the buffer, need to open new region or quit
+ if ( bcf_sr_regions_next(files->regions)<0 ) return -1;
+
+ for (i=0; i<files->nreaders; i++)
+ _reader_seek(&files->readers[i],files->regions->seq_names[files->regions->iseq],files->regions->start,files->regions->end);
+
+ return 0;
+}
+
+/*
+ * _reader_fill_buffer() - buffers all records with the same coordinate
+ */
+static void _reader_fill_buffer(bcf_srs_t *files, bcf_sr_t *reader)
+{
+ // Return if the buffer is full: the coordinate of the last buffered record differs
+ if ( reader->nbuffer && reader->buffer[reader->nbuffer]->pos != reader->buffer[1]->pos ) return;
+
+ // No iterator (sequence not present in this file) and not streaming
+ if ( !reader->itr && !files->streaming ) return;
+
+ // Fill the buffer with records starting at the same position
+ int i, ret = 0;
+ while (1)
+ {
+ if ( reader->nbuffer+1 >= reader->mbuffer )
+ {
+ // Increase buffer size
+ reader->mbuffer += 8;
+ reader->buffer = (bcf1_t**) realloc(reader->buffer, sizeof(bcf1_t*)*reader->mbuffer);
+ for (i=8; i>0; i--) // initialize
+ {
+ reader->buffer[reader->mbuffer-i] = bcf_init1();
+ reader->buffer[reader->mbuffer-i]->max_unpack = files->max_unpack;
+ reader->buffer[reader->mbuffer-i]->pos = -1; // for rare cases when VCF starts from 1
+ }
+ }
+ if ( files->streaming )
+ {
+ if ( reader->file->format.format==vcf )
+ {
+ if ( (ret=hts_getline(reader->file, KS_SEP_LINE, &files->tmps)) < 0 ) break; // no more lines
+ int ret = vcf_parse1(&files->tmps, reader->header, reader->buffer[reader->nbuffer+1]);
+ if ( ret<0 ) break;
+ }
+ else if ( reader->file->format.format==bcf )
+ {
+ if ( (ret=bcf_read1(reader->file, reader->header, reader->buffer[reader->nbuffer+1])) < 0 ) break; // no more lines
+ }
+ else
+ {
+ fprintf(stderr,"[%s:%d %s] fixme: not ready for this\n", __FILE__,__LINE__,__FUNCTION__);
+ exit(1);
+ }
+ }
+ else if ( reader->tbx_idx )
+ {
+ if ( (ret=tbx_itr_next(reader->file, reader->tbx_idx, reader->itr, &files->tmps)) < 0 ) break; // no more lines
+ vcf_parse1(&files->tmps, reader->header, reader->buffer[reader->nbuffer+1]);
+ }
+ else
+ {
+ if ( (ret=bcf_itr_next(reader->file, reader->itr, reader->buffer[reader->nbuffer+1])) < 0 ) break; // no more lines
+ bcf_subset_format(reader->header,reader->buffer[reader->nbuffer+1]);
+ }
+
+ // apply filter
+ if ( !reader->nfilter_ids )
+ bcf_unpack(reader->buffer[reader->nbuffer+1], BCF_UN_STR);
+ else
+ {
+ bcf_unpack(reader->buffer[reader->nbuffer+1], BCF_UN_STR|BCF_UN_FLT);
+ if ( !has_filter(reader, reader->buffer[reader->nbuffer+1]) ) continue;
+ }
+ reader->nbuffer++;
+
+ if ( reader->buffer[reader->nbuffer]->pos != reader->buffer[1]->pos ) break; // the buffer is full
+ }
+ if ( ret<0 )
+ {
+ // done for this region
+ tbx_itr_destroy(reader->itr);
+ reader->itr = NULL;
+ }
+ if ( files->collapse && reader->nbuffer>=2 && reader->buffer[1]->pos==reader->buffer[2]->pos )
+ collapse_buffer(files, reader);
+}
+
+/*
+ * _readers_shift_buffer() - removes the first line and all subsequent lines with the same position
+ */
+static void _reader_shift_buffer(bcf_sr_t *reader)
+{
+ int i;
+ for (i=2; i<=reader->nbuffer; i++)
+ if ( reader->buffer[i]->pos!=reader->buffer[1]->pos ) break;
+ if ( i<=reader->nbuffer )
+ {
+ // A record with a different position follows, swap it. Because of the reader's logic,
+ // only one such line can be present.
+ bcf1_t *tmp = reader->buffer[1]; reader->buffer[1] = reader->buffer[i]; reader->buffer[i] = tmp;
+ reader->nbuffer = 1;
+ }
+ else
+ reader->nbuffer = 0; // no other line
+}
+
+/*
+ * _reader_match_alleles() - from multiple buffered lines selects the one which
+ * corresponds best to the template line. The logic is controlled by COLLAPSE_*
+ * Returns 0 on success or -1 when no good matching line is found.
+ */
+static int _reader_match_alleles(bcf_srs_t *files, bcf_sr_t *reader, bcf1_t *tmpl)
+{
+ int i, irec = -1;
+
+ // if no template given, use the first available record
+ if ( !tmpl )
+ irec = 1;
+ else
+ {
+ int tmpl_type = bcf_get_variant_types(tmpl);
+ for (i=1; i<=reader->nbuffer; i++)
+ {
+ bcf1_t *line = reader->buffer[i];
+ if ( line->pos != reader->buffer[1]->pos ) break; // done with this reader
+
+ // Easiest case: matching by position only
+ if ( files->collapse&COLLAPSE_ANY ) { irec=i; break; }
+
+ int line_type = bcf_get_variant_types(line);
+
+ // No matter what the alleles are, as long as they are both SNPs
+ if ( files->collapse&COLLAPSE_SNPS && tmpl_type&VCF_SNP && line_type&VCF_SNP ) { irec=i; break; }
+ // ... or indels
+ if ( files->collapse&COLLAPSE_INDELS && tmpl_type&VCF_INDEL && line_type&VCF_INDEL ) { irec=i; break; }
+
+ // More thorough checking: REFs must match
+ if ( tmpl->rlen != line->rlen ) continue; // different length
+ if ( !tmpl->d.allele || !line->d.allele ) continue; // one of the lines is empty, someone is swapped buffered lines?!
+ if ( strcmp(tmpl->d.allele[0], line->d.allele[0]) ) continue; // the strings do not match
+
+ int ial,jal;
+ if ( files->collapse==COLLAPSE_NONE )
+ {
+ // Exact match, all alleles must be identical
+ if ( tmpl->n_allele!=line->n_allele ) continue; // different number of alleles, skip
+
+ int nmatch = 1; // REF has been already checked
+ for (ial=1; ial<tmpl->n_allele; ial++)
+ {
+ for (jal=1; jal<line->n_allele; jal++)
+ if ( !strcmp(tmpl->d.allele[ial], line->d.allele[jal]) ) { nmatch++; break; }
+ }
+ if ( nmatch==tmpl->n_allele ) { irec=i; break; } // found: exact match
+ continue;
+ }
+
+ if ( line->n_allele==1 && tmpl->n_allele==1 ) { irec=i; break; } // both sites are non-variant
+
+ // COLLAPSE_SOME: at least some ALTs must match
+ for (ial=1; ial<tmpl->n_allele; ial++)
+ {
+ for (jal=1; jal<line->n_allele; jal++)
+ if ( !strcmp(tmpl->d.allele[ial], line->d.allele[jal]) ) { irec=i; break; }
+ if ( irec>=1 ) break;
+ }
+ if ( irec>=1 ) break;
+ }
+ if ( irec==-1 ) return -1; // no matching line was found
+ }
+
+ // Set the selected line (irec) as active: set it to buffer[0], move the remaining lines forward
+ // and put the old bcf1_t record at the end.
+ bcf1_t *tmp = reader->buffer[0];
+ reader->buffer[0] = reader->buffer[irec];
+ for (i=irec+1; i<=reader->nbuffer; i++) reader->buffer[i-1] = reader->buffer[i];
+ reader->buffer[ reader->nbuffer ] = tmp;
+ reader->nbuffer--;
+
+ return 0;
+}
+
+int _reader_next_line(bcf_srs_t *files)
+{
+ int i, min_pos = INT_MAX;
+
+ // Loop until next suitable line is found or all readers have finished
+ while ( 1 )
+ {
+ // Get all readers ready for the next region.
+ if ( files->regions && _readers_next_region(files)<0 ) break;
+
+ // Fill buffers
+ const char *chr = NULL;
+ for (i=0; i<files->nreaders; i++)
+ {
+ _reader_fill_buffer(files, &files->readers[i]);
+
+ // Update the minimum coordinate
+ if ( !files->readers[i].nbuffer ) continue;
+ if ( min_pos > files->readers[i].buffer[1]->pos )
+ {
+ min_pos = files->readers[i].buffer[1]->pos;
+ chr = bcf_seqname(files->readers[i].header, files->readers[i].buffer[1]);
+ }
+ }
+ if ( min_pos==INT_MAX )
+ {
+ if ( !files->regions ) break;
+ continue;
+ }
+
+ // Skip this position if not present in targets
+ if ( files->targets )
+ {
+ int ret = bcf_sr_regions_overlap(files->targets, chr, min_pos, min_pos);
+ if ( (!files->targets_exclude && ret<0) || (files->targets_exclude && !ret) )
+ {
+ // Remove all lines with this position from the buffer
+ for (i=0; i<files->nreaders; i++)
+ if ( files->readers[i].nbuffer && files->readers[i].buffer[1]->pos==min_pos )
+ _reader_shift_buffer(&files->readers[i]);
+ min_pos = INT_MAX;
+ continue;
+ }
+ }
+
+ break; // done: min_pos is set
+ }
+
+ // There can be records with duplicate positions. Set the active line intelligently so that
+ // the alleles match.
+ int nret = 0; // number of readers sharing the position
+ bcf1_t *first = NULL; // record which will be used for allele matching
+ for (i=0; i<files->nreaders; i++)
+ {
+ files->has_line[i] = 0;
+
+ // Skip readers with no records at this position
+ if ( !files->readers[i].nbuffer || files->readers[i].buffer[1]->pos!=min_pos ) continue;
+
+ // Until now buffer[0] of all reader was empty and the lines started at buffer[1].
+ // Now lines which are ready to be output will be moved to buffer[0].
+ if ( _reader_match_alleles(files, &files->readers[i], first) < 0 ) continue;
+ if ( !first ) first = files->readers[i].buffer[0];
+
+ nret++;
+ files->has_line[i] = 1;
+ }
+ return nret;
+}
+
+int bcf_sr_next_line(bcf_srs_t *files)
+{
+ if ( !files->targets_als )
+ return _reader_next_line(files);
+
+ while (1)
+ {
+ int i, ret = _reader_next_line(files);
+ if ( !ret ) return ret;
+
+ for (i=0; i<files->nreaders; i++)
+ if ( files->has_line[i] ) break;
+
+ if ( _regions_match_alleles(files->targets, files->targets_als-1, files->readers[i].buffer[0]) ) return ret;
+
+ // Check if there are more duplicate lines in the buffers. If not, return this line as if it
+ // matched the targets, even if there is a type mismatch
+ for (i=0; i<files->nreaders; i++)
+ {
+ if ( !files->has_line[i] ) continue;
+ if ( files->readers[i].nbuffer==0 || files->readers[i].buffer[1]->pos!=files->readers[i].buffer[0]->pos ) continue;
+ break;
+ }
+ if ( i==files->nreaders ) return ret; // no more lines left, output even if target alleles are not of the same type
+ }
+}
+
+static void bcf_sr_seek_start(bcf_srs_t *readers)
+{
+ bcf_sr_regions_t *reg = readers->regions;
+ int i;
+ for (i=0; i<reg->nseqs; i++)
+ reg->regs[i].creg = -1;
+ reg->iseq = 0;
+}
+
+
+int bcf_sr_seek(bcf_srs_t *readers, const char *seq, int pos)
+{
+ if ( !readers->regions ) return 0;
+ if ( !seq && !pos )
+ {
+ // seek to start
+ bcf_sr_seek_start(readers);
+ return 0;
+ }
+ bcf_sr_regions_overlap(readers->regions, seq, pos, pos);
+ int i, nret = 0;
+ for (i=0; i<readers->nreaders; i++)
+ {
+ nret += _reader_seek(&readers->readers[i],seq,pos,MAX_CSI_COOR-1);
+ }
+ return nret;
+}
+
+int bcf_sr_set_samples(bcf_srs_t *files, const char *fname, int is_file)
+{
+ int i, j, nsmpl, free_smpl = 0;
+ char **smpl = NULL;
+
+ void *exclude = (fname[0]=='^') ? khash_str2int_init() : NULL;
+ if ( exclude || strcmp("-",fname) ) // "-" stands for all samples
+ {
+ smpl = hts_readlist(fname, is_file, &nsmpl);
+ if ( !smpl )
+ {
+ fprintf(stderr,"Could not read the file: \"%s\"\n", fname);
+ return 0;
+ }
+ if ( exclude )
+ {
+ for (i=0; i<nsmpl; i++)
+ khash_str2int_inc(exclude, smpl[i]);
+ }
+ free_smpl = 1;
+ }
+ if ( !smpl )
+ {
+ smpl = files->readers[0].header->samples; // intersection of all samples
+ nsmpl = bcf_hdr_nsamples(files->readers[0].header);
+ }
+
+ files->samples = NULL;
+ files->n_smpl = 0;
+ for (i=0; i<nsmpl; i++)
+ {
+ if ( exclude && khash_str2int_has_key(exclude,smpl[i]) ) continue;
+
+ int n_isec = 0;
+ for (j=0; j<files->nreaders; j++)
+ {
+ if ( bcf_hdr_id2int(files->readers[j].header, BCF_DT_SAMPLE, smpl[i])<0 ) break;
+ n_isec++;
+ }
+ if ( n_isec!=files->nreaders )
+ {
+ fprintf(stderr,"Warning: The sample \"%s\" was not found in %s, skipping\n", smpl[i], files->readers[n_isec].fname);
+ continue;
+ }
+
+ files->samples = (char**) realloc(files->samples, (files->n_smpl+1)*sizeof(const char*));
+ files->samples[files->n_smpl++] = strdup(smpl[i]);
+ }
+
+ if ( exclude ) khash_str2int_destroy(exclude);
+ if ( free_smpl )
+ {
+ for (i=0; i<nsmpl; i++) free(smpl[i]);
+ free(smpl);
+ }
+
+ if ( !files->n_smpl )
+ {
+ if ( files->nreaders>1 )
+ fprintf(stderr,"No samples in common.\n");
+ return 0;
+ }
+ for (i=0; i<files->nreaders; i++)
+ {
+ bcf_sr_t *reader = &files->readers[i];
+ reader->samples = (int*) malloc(sizeof(int)*files->n_smpl);
+ reader->n_smpl = files->n_smpl;
+ for (j=0; j<files->n_smpl; j++)
+ reader->samples[j] = bcf_hdr_id2int(reader->header, BCF_DT_SAMPLE, files->samples[j]);
+ }
+ return 1;
+}
+
+// Add a new region into a list sorted by start,end. On input the coordinates
+// are 1-based, stored 0-based, inclusive.
+static void _regions_add(bcf_sr_regions_t *reg, const char *chr, int start, int end)
+{
+ if ( start==-1 && end==-1 )
+ {
+ start = 0; end = MAX_CSI_COOR-1;
+ }
+ else
+ {
+ start--; end--; // store 0-based coordinates
+ }
+
+ if ( !reg->seq_hash )
+ reg->seq_hash = khash_str2int_init();
+
+ int iseq;
+ if ( khash_str2int_get(reg->seq_hash, chr, &iseq)<0 )
+ {
+ // the chromosome block does not exist
+ iseq = reg->nseqs++;
+ reg->seq_names = (char**) realloc(reg->seq_names,sizeof(char*)*reg->nseqs);
+ reg->regs = (region_t*) realloc(reg->regs,sizeof(region_t)*reg->nseqs);
+ memset(®->regs[reg->nseqs-1],0,sizeof(region_t));
+ reg->seq_names[iseq] = strdup(chr);
+ reg->regs[iseq].creg = -1;
+ khash_str2int_set(reg->seq_hash,reg->seq_names[iseq],iseq);
+ }
+
+ region_t *creg = ®->regs[iseq];
+
+ // the regions may not be sorted on input: binary search
+ int i, min = 0, max = creg->nregs - 1;
+ while ( min<=max )
+ {
+ i = (max+min)/2;
+ if ( start < creg->regs[i].start ) max = i - 1;
+ else if ( start > creg->regs[i].start ) min = i + 1;
+ else break;
+ }
+ if ( min>max || creg->regs[i].start!=start || creg->regs[i].end!=end )
+ {
+ // no such region, insert a new one just after max
+ hts_expand(region1_t,creg->nregs+1,creg->mregs,creg->regs);
+ if ( ++max < creg->nregs )
+ memmove(&creg->regs[max+1],&creg->regs[max],(creg->nregs - max)*sizeof(region1_t));
+ creg->regs[max].start = start;
+ creg->regs[max].end = end;
+ creg->nregs++;
+ }
+}
+
+// File name or a list of genomic locations. If file name, NULL is returned.
+static bcf_sr_regions_t *_regions_init_string(const char *str)
+{
+ bcf_sr_regions_t *reg = (bcf_sr_regions_t *) calloc(1, sizeof(bcf_sr_regions_t));
+ reg->start = reg->end = -1;
+ reg->prev_start = reg->prev_seq = -1;
+
+ kstring_t tmp = {0,0,0};
+ const char *sp = str, *ep = str;
+ int from, to;
+ while ( 1 )
+ {
+ while ( *ep && *ep!=',' && *ep!=':' ) ep++;
+ tmp.l = 0;
+ kputsn(sp,ep-sp,&tmp);
+ if ( *ep==':' )
+ {
+ sp = ep+1;
+ from = hts_parse_decimal(sp,(char**)&ep,0);
+ if ( sp==ep )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not parse the region(s): %s\n", __FILE__,__LINE__,__FUNCTION__,str);
+ free(reg); free(tmp.s); return NULL;
+ }
+ if ( !*ep || *ep==',' )
+ {
+ _regions_add(reg, tmp.s, from, from);
+ sp = ep;
+ continue;
+ }
+ if ( *ep!='-' )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not parse the region(s): %s\n", __FILE__,__LINE__,__FUNCTION__,str);
+ free(reg); free(tmp.s); return NULL;
+ }
+ ep++;
+ sp = ep;
+ to = hts_parse_decimal(sp,(char**)&ep,0);
+ if ( *ep && *ep!=',' )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not parse the region(s): %s\n", __FILE__,__LINE__,__FUNCTION__,str);
+ free(reg); free(tmp.s); return NULL;
+ }
+ if ( sp==ep ) to = MAX_CSI_COOR-1;
+ _regions_add(reg, tmp.s, from, to);
+ if ( !*ep ) break;
+ sp = ep;
+ }
+ else
+ {
+ if ( tmp.l ) _regions_add(reg, tmp.s, -1, -1);
+ if ( !*ep ) break;
+ sp = ++ep;
+ }
+ }
+ free(tmp.s);
+ return reg;
+}
+
+// ichr,ifrom,ito are 0-based;
+// returns -1 on error, 0 if the line is a comment line, 1 on success
+static int _regions_parse_line(char *line, int ichr,int ifrom,int ito, char **chr,char **chr_end,int *from,int *to)
+{
+ *chr_end = NULL;
+
+ if ( line[0]=='#' ) return 0;
+
+ int k,l; // index of the start and end column of the tab-delimited file
+ if ( ifrom <= ito )
+ k = ifrom, l = ito;
+ else
+ l = ifrom, k = ito;
+
+ int i;
+ char *se = line, *ss = NULL; // start and end
+ char *tmp;
+ for (i=0; i<=k && *se; i++)
+ {
+ ss = i==0 ? se++ : ++se;
+ while (*se && *se!='\t') se++;
+ }
+ if ( i<=k ) return -1;
+ if ( k==l )
+ {
+ *from = *to = hts_parse_decimal(ss, &tmp, 0);
+ if ( tmp==ss ) return -1;
+ }
+ else
+ {
+ if ( k==ifrom )
+ *from = hts_parse_decimal(ss, &tmp, 0);
+ else
+ *to = hts_parse_decimal(ss, &tmp, 0);
+ if ( ss==tmp ) return -1;
+
+ for (i=k; i<l && *se; i++)
+ {
+ ss = ++se;
+ while (*se && *se!='\t') se++;
+ }
+ if ( i<l ) return -1;
+ if ( k==ifrom )
+ *to = hts_parse_decimal(ss, &tmp, 0);
+ else
+ *from = hts_parse_decimal(ss, &tmp, 0);
+ if ( ss==tmp ) return -1;
+ }
+
+ ss = se = line;
+ for (i=0; i<=ichr && *se; i++)
+ {
+ if ( i>0 ) ss = ++se;
+ while (*se && *se!='\t') se++;
+ }
+ if ( i<=ichr ) return -1;
+ *chr_end = se;
+ *chr = ss;
+ return 1;
+}
+
+bcf_sr_regions_t *bcf_sr_regions_init(const char *regions, int is_file, int ichr, int ifrom, int ito)
+{
+ bcf_sr_regions_t *reg;
+ if ( !is_file ) return _regions_init_string(regions);
+
+ reg = (bcf_sr_regions_t *) calloc(1, sizeof(bcf_sr_regions_t));
+ reg->start = reg->end = -1;
+ reg->prev_start = reg->prev_seq = -1;
+
+ reg->file = hts_open(regions, "rb");
+ if ( !reg->file )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not open file: %s\n", __FILE__,__LINE__,__FUNCTION__,regions);
+ free(reg);
+ return NULL;
+ }
+
+ reg->tbx = tbx_index_load(regions);
+ if ( !reg->tbx )
+ {
+ int len = strlen(regions);
+ int is_bed = strcasecmp(".bed",regions+len-4) ? 0 : 1;
+ if ( !is_bed && !strcasecmp(".bed.gz",regions+len-7) ) is_bed = 1;
+
+ if ( reg->file->format.format==vcf ) ito = 1;
+
+ // read the whole file, tabix index is not present
+ while ( hts_getline(reg->file, KS_SEP_LINE, ®->line) > 0 )
+ {
+ char *chr, *chr_end;
+ int from, to, ret;
+ ret = _regions_parse_line(reg->line.s, ichr,ifrom,abs(ito), &chr,&chr_end,&from,&to);
+ if ( ret < 0 )
+ {
+ if ( ito<0 )
+ ret = _regions_parse_line(reg->line.s, ichr,ifrom,ifrom, &chr,&chr_end,&from,&to);
+ if ( ret<0 )
+ {
+ fprintf(stderr,"[%s:%d] Could not parse the file %s, using the columns %d,%d[,%d]\n", __FILE__,__LINE__,regions,ichr+1,ifrom+1,ito+1);
+ hts_close(reg->file); reg->file = NULL; free(reg);
+ return NULL;
+ }
+ }
+ if ( !ret ) continue;
+ if ( is_bed ) from++;
+ *chr_end = 0;
+ _regions_add(reg, chr, from, to);
+ *chr_end = '\t';
+ }
+ hts_close(reg->file); reg->file = NULL;
+ if ( !reg->nseqs ) { free(reg); return NULL; }
+ return reg;
+ }
+
+ reg->seq_names = (char**) tbx_seqnames(reg->tbx, ®->nseqs);
+ if ( !reg->seq_hash )
+ reg->seq_hash = khash_str2int_init();
+ int i;
+ for (i=0; i<reg->nseqs; i++)
+ {
+ khash_str2int_set(reg->seq_hash,reg->seq_names[i],i);
+ }
+ reg->fname = strdup(regions);
+ reg->is_bin = 1;
+ return reg;
+}
+
+void bcf_sr_regions_destroy(bcf_sr_regions_t *reg)
+{
+ int i;
+ free(reg->fname);
+ if ( reg->itr ) tbx_itr_destroy(reg->itr);
+ if ( reg->tbx ) tbx_destroy(reg->tbx);
+ if ( reg->file ) hts_close(reg->file);
+ if ( reg->als ) free(reg->als);
+ if ( reg->als_str.s ) free(reg->als_str.s);
+ free(reg->line.s);
+ if ( reg->regs )
+ {
+ // free only in-memory names, tbx names are const
+ for (i=0; i<reg->nseqs; i++)
+ {
+ free(reg->seq_names[i]);
+ free(reg->regs[i].regs);
+ }
+ }
+ free(reg->regs);
+ free(reg->seq_names);
+ khash_str2int_destroy(reg->seq_hash);
+ free(reg);
+}
+
+int bcf_sr_regions_seek(bcf_sr_regions_t *reg, const char *seq)
+{
+ reg->iseq = reg->start = reg->end = -1;
+ if ( khash_str2int_get(reg->seq_hash, seq, ®->iseq) < 0 ) return -1; // sequence seq not in regions
+
+ // using in-memory regions
+ if ( reg->regs )
+ {
+ reg->regs[reg->iseq].creg = -1;
+ return 0;
+ }
+
+ // reading regions from tabix
+ if ( reg->itr ) tbx_itr_destroy(reg->itr);
+ reg->itr = tbx_itr_querys(reg->tbx, seq);
+ if ( reg->itr ) return 0;
+
+ return -1;
+}
+
+int bcf_sr_regions_next(bcf_sr_regions_t *reg)
+{
+ if ( reg->iseq<0 ) return -1;
+ reg->start = reg->end = -1;
+ reg->nals = 0;
+
+ // using in-memory regions
+ if ( reg->regs )
+ {
+ while ( reg->iseq < reg->nseqs )
+ {
+ reg->regs[reg->iseq].creg++;
+ if ( reg->regs[reg->iseq].creg < reg->regs[reg->iseq].nregs ) break;
+ reg->iseq++;
+ }
+ if ( reg->iseq >= reg->nseqs ) { reg->iseq = -1; return -1; } // no more regions left
+ region1_t *creg = ®->regs[reg->iseq].regs[reg->regs[reg->iseq].creg];
+ reg->start = creg->start;
+ reg->end = creg->end;
+ return 0;
+ }
+
+ // reading from tabix
+ char *chr, *chr_end;
+ int ichr = 0, ifrom = 1, ito = 2, is_bed = 0, from, to;
+ if ( reg->tbx )
+ {
+ ichr = reg->tbx->conf.sc-1;
+ ifrom = reg->tbx->conf.bc-1;
+ ito = reg->tbx->conf.ec-1;
+ if ( ito<0 ) ito = ifrom;
+ is_bed = reg->tbx->conf.preset==TBX_UCSC ? 1 : 0;
+ }
+
+ int ret = 0;
+ while ( !ret )
+ {
+ if ( reg->itr )
+ {
+ // tabix index present, reading a chromosome block
+ ret = tbx_itr_next(reg->file, reg->tbx, reg->itr, ®->line);
+ if ( ret<0 ) { reg->iseq = -1; return -1; }
+ }
+ else
+ {
+ if ( reg->is_bin )
+ {
+ // Waited for seek which never came. Reopen in text mode and stream
+ // through the regions, otherwise hts_getline would fail
+ hts_close(reg->file);
+ reg->file = hts_open(reg->fname, "r");
+ if ( !reg->file )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not open file: %s\n", __FILE__,__LINE__,__FUNCTION__,reg->fname);
+ reg->file = NULL;
+ bcf_sr_regions_destroy(reg);
+ return -1;
+ }
+ reg->is_bin = 0;
+ }
+
+ // tabix index absent, reading the whole file
+ ret = hts_getline(reg->file, KS_SEP_LINE, ®->line);
+ if ( ret<0 ) { reg->iseq = -1; return -1; }
+ }
+ ret = _regions_parse_line(reg->line.s, ichr,ifrom,ito, &chr,&chr_end,&from,&to);
+ if ( ret<0 )
+ {
+ fprintf(stderr,"[%s:%d] Could not parse the file %s, using the columns %d,%d,%d\n", __FILE__,__LINE__,reg->fname,ichr+1,ifrom+1,ito+1);
+ return -1;
+ }
+ }
+ if ( is_bed ) from++;
+
+ *chr_end = 0;
+ if ( khash_str2int_get(reg->seq_hash, chr, ®->iseq)<0 )
+ {
+ fprintf(stderr,"Broken tabix index? The sequence \"%s\" not in dictionary [%s]\n", chr,reg->line.s);
+ exit(1);
+ }
+ *chr_end = '\t';
+
+ reg->start = from - 1;
+ reg->end = to - 1;
+ return 0;
+}
+
+static int _regions_match_alleles(bcf_sr_regions_t *reg, int als_idx, bcf1_t *rec)
+{
+ if ( reg->regs )
+ {
+ // payload is not supported for in-memory regions, switch to regidx instead in future
+ fprintf(stderr,"Error: Compressed and indexed targets file is required\n");
+ exit(1);
+ }
+
+ int i = 0, max_len = 0;
+ if ( !reg->nals )
+ {
+ char *ss = reg->line.s;
+ while ( i<als_idx && *ss )
+ {
+ if ( *ss=='\t' ) i++;
+ ss++;
+ }
+ char *se = ss;
+ reg->nals = 1;
+ while ( *se && *se!='\t' )
+ {
+ if ( *se==',' ) reg->nals++;
+ se++;
+ }
+ ks_resize(®->als_str, se-ss+1+reg->nals);
+ reg->als_str.l = 0;
+ hts_expand(char*,reg->nals,reg->mals,reg->als);
+ reg->nals = 0;
+
+ se = ss;
+ while ( *(++se) )
+ {
+ if ( *se=='\t' ) break;
+ if ( *se!=',' ) continue;
+ reg->als[reg->nals] = ®->als_str.s[reg->als_str.l];
+ kputsn(ss,se-ss,®->als_str);
+ if ( ®->als_str.s[reg->als_str.l] - reg->als[reg->nals] > max_len ) max_len = ®->als_str.s[reg->als_str.l] - reg->als[reg->nals];
+ reg->als_str.l++;
+ reg->nals++;
+ ss = ++se;
+ }
+ reg->als[reg->nals] = ®->als_str.s[reg->als_str.l];
+ kputsn(ss,se-ss,®->als_str);
+ if ( ®->als_str.s[reg->als_str.l] - reg->als[reg->nals] > max_len ) max_len = ®->als_str.s[reg->als_str.l] - reg->als[reg->nals];
+ reg->nals++;
+ reg->als_type = max_len > 1 ? VCF_INDEL : VCF_SNP; // this is a simplified check, see vcf.c:bcf_set_variant_types
+ }
+ int type = bcf_get_variant_types(rec);
+ if ( reg->als_type & VCF_INDEL )
+ return type & VCF_INDEL ? 1 : 0;
+ return !(type & VCF_INDEL) ? 1 : 0;
+}
+
+int bcf_sr_regions_overlap(bcf_sr_regions_t *reg, const char *seq, int start, int end)
+{
+ int iseq;
+ if ( khash_str2int_get(reg->seq_hash, seq, &iseq)<0 ) return -1; // no such sequence
+
+ if ( reg->prev_seq==-1 || iseq!=reg->prev_seq || reg->prev_start > start ) // new chromosome or after a seek
+ {
+ // flush regions left on previous chromosome
+ if ( reg->missed_reg_handler && reg->prev_seq!=-1 && reg->iseq!=-1 )
+ bcf_sr_regions_flush(reg);
+
+ bcf_sr_regions_seek(reg, seq);
+ reg->start = reg->end = -1;
+ }
+ if ( reg->prev_seq==iseq && reg->iseq!=iseq ) return -2; // no more regions on this chromosome
+ reg->prev_seq = reg->iseq;
+ reg->prev_start = start;
+
+ while ( iseq==reg->iseq && reg->end < start )
+ {
+ if ( bcf_sr_regions_next(reg) < 0 ) return -2; // no more regions left
+ if ( reg->iseq != iseq ) return -1; // does not overlap any regions
+ if ( reg->missed_reg_handler && reg->end < start ) reg->missed_reg_handler(reg, reg->missed_reg_data);
+ }
+ if ( reg->start <= end ) return 0; // region overlap
+ return -1; // no overlap
+}
+
+void bcf_sr_regions_flush(bcf_sr_regions_t *reg)
+{
+ if ( !reg->missed_reg_handler || reg->prev_seq==-1 ) return;
+ while ( !bcf_sr_regions_next(reg) ) reg->missed_reg_handler(reg, reg->missed_reg_data);
+ return;
+}
+
--- /dev/null
+.TH tabix 1 "22 April 2016" "htslib-1.3.1" "Bioinformatics tools"
+.SH NAME
+.PP
+bgzip \- Block compression/decompression utility
+.PP
+tabix \- Generic indexer for TAB-delimited genome position files
+.\"
+.\" Copyright (C) 2009-2011 Broad Institute.
+.\"
+.\" Author: Heng Li <lh3@sanger.ac.uk>
+.\"
+.\" Permission is hereby granted, free of charge, to any person obtaining a
+.\" copy of this software and associated documentation files (the "Software"),
+.\" to deal in the Software without restriction, including without limitation
+.\" the rights to use, copy, modify, merge, publish, distribute, sublicense,
+.\" and/or sell copies of the Software, and to permit persons to whom the
+.\" Software is furnished to do so, subject to the following conditions:
+.\"
+.\" The above copyright notice and this permission notice shall be included in
+.\" all copies or substantial portions of the Software.
+.\"
+.\" THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+.\" IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+.\" FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+.\" THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+.\" LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+.\" FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+.\" DEALINGS IN THE SOFTWARE.
+.\"
+.SH SYNOPSIS
+.PP
+.B bgzip
+.RB [ -cdhB ]
+.RB [ -b
+.IR virtualOffset ]
+.RB [ -s
+.IR size ]
+.RI [ file ]
+.PP
+.B tabix
+.RB [ -0lf ]
+.RB [ -p
+gff|bed|sam|vcf]
+.RB [ -s
+.IR seqCol ]
+.RB [ -b
+.IR begCol ]
+.RB [ -e
+.IR endCol ]
+.RB [ -S
+.IR lineSkip ]
+.RB [ -c
+.IR metaChar ]
+.I in.tab.bgz
+.RI [ "region1 " [ "region2 " [ ... "]]]"
+
+.SH DESCRIPTION
+.PP
+Tabix indexes a TAB-delimited genome position file
+.I in.tab.bgz
+and creates an index file (
+.I in.tab.bgz.tbi
+or
+.I in.tab.bgz.csi
+) when
+.I region
+is absent from the command-line. The input data file must be position
+sorted and compressed by
+.B bgzip
+which has a
+.BR gzip (1)
+like interface. After indexing, tabix is able to quickly retrieve data
+lines overlapping
+.I regions
+specified in the format "chr:beginPos-endPos". Fast data retrieval also
+works over network if URI is given as a file name and in this case the
+index file will be downloaded if it is not present locally.
+
+.SH INDEXING OPTIONS
+.TP 10
+.B -0, --zero-based
+Specify that the position in the data file is 0-based (e.g. UCSC files)
+rather than 1-based.
+.TP
+.BI "-b, --begin " INT
+Column of start chromosomal position. [4]
+.TP
+.BI "-c, --comment " CHAR
+Skip lines started with character CHAR. [#]
+.TP
+.BI "-C, --csi"
+Produce CSI format index instead of classical tabix or BAI style indices.
+.TP
+.BI "-e, --end " INT
+Column of end chromosomal position. The end column can be the same as the
+start column. [5]
+.TP
+.B "-f, --force "
+Force to overwrite the index file if it is present.
+.TP
+.BI "-m, --min-shift" INT
+set minimal interval size for CSI indices to 2^INT [14]
+.TP
+.BI "-p, --preset " STR
+Input format for indexing. Valid values are: gff, bed, sam, vcf.
+This option should not be applied together with any of
+.BR -s ", " -b ", " -e ", " -c " and " -0 ;
+it is not used for data retrieval because this setting is stored in
+the index file. [gff]
+.TP
+.BI "-s, --sequence " INT
+Column of sequence name. Option
+.BR -s ", " -b ", " -e ", " -S ", " -c " and " -0
+are all stored in the index file and thus not used in data retrieval. [1]
+.TP
+.BI "-S, --skip-lines " INT
+Skip first INT lines in the data file. [0]
+
+.SH QUERYING AND OTHER OPTIONS
+.TP
+.B "-h, --print-header "
+Print also the header/meta lines.
+.TP
+.B "-H, --only-header "
+Print only the header/meta lines.
+.TP
+.B "-l, --list-chroms "
+List the sequence names stored in the index file.
+.TP
+.B "-r, --reheader " FILE
+Replace the header with the content of FILE
+.TP
+.B "-R, --regions " FILE
+Restrict to regions listed in the FILE. The FILE can be BED file (requires .bed, .bed.gz, .bed.bgz
+file name extension) or a TAB-delimited file with CHROM, POS, and, optionally,
+POS_TO columns, where positions are 1-based and inclusive. When this option is in use, the input
+file may not be sorted.
+regions.
+.TP
+.B "-T, --targets" FILE
+Similar to
+.B -R
+but the entire input will be read sequentially and regions not listed in FILE will be skipped.
+.PP
+.SH EXAMPLE
+(grep ^"#" in.gff; grep -v ^"#" in.gff | sort -k1,1 -k4,4n) | bgzip > sorted.gff.gz;
+
+tabix -p gff sorted.gff.gz;
+
+tabix sorted.gff.gz chr1:10,000,000-20,000,000;
+
+.SH NOTES
+It is straightforward to achieve overlap queries using the standard
+B-tree index (with or without binning) implemented in all SQL databases,
+or the R-tree index in PostgreSQL and Oracle. But there are still many
+reasons to use tabix. Firstly, tabix directly works with a lot of widely
+used TAB-delimited formats such as GFF/GTF and BED. We do not need to
+design database schema or specialized binary formats. Data do not need
+to be duplicated in different formats, either. Secondly, tabix works on
+compressed data files while most SQL databases do not. The GenCode
+annotation GTF can be compressed down to 4%. Thirdly, tabix is
+fast. The same indexing algorithm is known to work efficiently for an
+alignment with a few billion short reads. SQL databases probably cannot
+easily handle data at this scale. Last but not the least, tabix supports
+remote data retrieval. One can put the data file and the index at an FTP
+or HTTP server, and other users or even web services will be able to get
+a slice without downloading the entire file.
+
+.SH AUTHOR
+.PP
+Tabix was written by Heng Li. The BGZF library was originally
+implemented by Bob Handsaker and modified by Heng Li for remote file
+access and in-memory caching.
+
+.SH SEE ALSO
+.PP
+.BR samtools (1)
--- /dev/null
+/* tabix.c -- Generic indexer for TAB-delimited genome position files.
+
+ Copyright (C) 2009-2011 Broad Institute.
+ Copyright (C) 2010-2012, 2014-2016 Genome Research Ltd.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <stdlib.h>
+#include <unistd.h>
+#include <string.h>
+#include <getopt.h>
+#include <sys/types.h>
+#include <sys/stat.h>
+#include <errno.h>
+#include "htslib/tbx.h"
+#include "htslib/sam.h"
+#include "htslib/vcf.h"
+#include "htslib/kseq.h"
+#include "htslib/bgzf.h"
+#include "htslib/hts.h"
+#include "htslib/regidx.h"
+
+typedef struct
+{
+ char *regions_fname, *targets_fname;
+ int print_header, header_only;
+}
+args_t;
+
+static void error(const char *format, ...)
+{
+ va_list ap;
+ va_start(ap, format);
+ vfprintf(stderr, format, ap);
+ va_end(ap);
+ exit(EXIT_FAILURE);
+}
+
+#define IS_GFF (1<<0)
+#define IS_BED (1<<1)
+#define IS_SAM (1<<2)
+#define IS_VCF (1<<3)
+#define IS_BCF (1<<4)
+#define IS_BAM (1<<5)
+#define IS_CRAM (1<<6)
+#define IS_TXT (IS_GFF|IS_BED|IS_SAM|IS_VCF)
+
+int file_type(const char *fname)
+{
+ int l = strlen(fname);
+ int strcasecmp(const char *s1, const char *s2);
+ if (l>=7 && strcasecmp(fname+l-7, ".gff.gz") == 0) return IS_GFF;
+ else if (l>=7 && strcasecmp(fname+l-7, ".bed.gz") == 0) return IS_BED;
+ else if (l>=7 && strcasecmp(fname+l-7, ".sam.gz") == 0) return IS_SAM;
+ else if (l>=7 && strcasecmp(fname+l-7, ".vcf.gz") == 0) return IS_VCF;
+ else if (l>=4 && strcasecmp(fname+l-4, ".bcf") == 0) return IS_BCF;
+ else if (l>=4 && strcasecmp(fname+l-4, ".bam") == 0) return IS_BAM;
+ else if (l>=4 && strcasecmp(fname+l-5, ".cram") == 0) return IS_CRAM;
+
+ htsFile *fp = hts_open(fname,"r");
+ enum htsExactFormat format = fp->format.format;
+ hts_close(fp);
+ if ( format == bcf ) return IS_BCF;
+ if ( format == bam ) return IS_BAM;
+ if ( format == cram ) return IS_CRAM;
+ if ( format == vcf ) return IS_VCF;
+
+ return 0;
+}
+
+static char **parse_regions(char *regions_fname, char **argv, int argc, int *nregs)
+{
+ kstring_t str = {0,0,0};
+ int iseq = 0, ireg = 0;
+ char **regs = NULL;
+ *nregs = argc;
+
+ if ( regions_fname )
+ {
+ // improve me: this is a too heavy machinery for parsing regions...
+
+ regidx_t *idx = regidx_init(regions_fname, NULL, NULL, 0, NULL);
+ if ( !idx ) error("Could not read %s\n", regions_fname);
+
+ (*nregs) += regidx_nregs(idx);
+ regs = (char**) malloc(sizeof(char*)*(*nregs));
+
+ int nseq;
+ char **seqs = regidx_seq_names(idx, &nseq);
+ for (iseq=0; iseq<nseq; iseq++)
+ {
+ regitr_t itr;
+ regidx_overlap(idx, seqs[iseq], 0, UINT32_MAX, &itr);
+ while ( itr.i < itr.n )
+ {
+ str.l = 0;
+ ksprintf(&str, "%s:%d-%d", seqs[iseq], REGITR_START(itr)+1, REGITR_END(itr)+1);
+ regs[ireg++] = strdup(str.s);
+ itr.i++;
+ }
+ }
+ regidx_destroy(idx);
+ }
+ free(str.s);
+
+ if ( !ireg )
+ {
+ if ( argc )
+ regs = (char**) malloc(sizeof(char*)*argc);
+ else
+ {
+ regs = (char**) malloc(sizeof(char*));
+ regs[0] = strdup(".");
+ *nregs = 1;
+ }
+ }
+
+ for (iseq=0; iseq<argc; iseq++) regs[ireg++] = strdup(argv[iseq]);
+ return regs;
+}
+static int query_regions(args_t *args, char *fname, char **regs, int nregs)
+{
+ int i;
+ htsFile *fp = hts_open(fname,"r");
+ if ( !fp ) error("Could not read %s\n", fname);
+ enum htsExactFormat format = hts_get_format(fp)->format;
+
+ regidx_t *reg_idx = NULL;
+ if ( args->targets_fname )
+ {
+ reg_idx = regidx_init(args->targets_fname, NULL, NULL, 0, NULL);
+ if ( !reg_idx ) error("Could not read %s\n", args->targets_fname);
+ }
+
+ if ( format == bcf )
+ {
+ htsFile *out = hts_open("-","w");
+ if ( !out ) error("Could not open stdout\n", fname);
+ hts_idx_t *idx = bcf_index_load(fname);
+ if ( !idx ) error("Could not load .csi index of %s\n", fname);
+ bcf_hdr_t *hdr = bcf_hdr_read(fp);
+ if ( !hdr ) error("Could not read the header: %s\n", fname);
+ if ( args->print_header )
+ bcf_hdr_write(out,hdr);
+ if ( !args->header_only )
+ {
+ bcf1_t *rec = bcf_init();
+ for (i=0; i<nregs; i++)
+ {
+ hts_itr_t *itr = bcf_itr_querys(idx,hdr,regs[i]);
+ while ( bcf_itr_next(fp, itr, rec) >=0 )
+ {
+ if ( reg_idx && !regidx_overlap(reg_idx, bcf_seqname(hdr,rec),rec->pos,rec->pos+rec->rlen-1, NULL) ) continue;
+ bcf_write(out,hdr,rec);
+ }
+ tbx_itr_destroy(itr);
+ }
+ bcf_destroy(rec);
+ }
+ if ( hts_close(out) ) error("hts_close returned non-zero status for stdout\n");
+ bcf_hdr_destroy(hdr);
+ hts_idx_destroy(idx);
+ }
+ else if ( format==vcf || format==sam || format==unknown_format )
+ {
+ tbx_t *tbx = tbx_index_load(fname);
+ if ( !tbx ) error("Could not load .tbi/.csi index of %s\n", fname);
+ kstring_t str = {0,0,0};
+ if ( args->print_header )
+ {
+ while ( hts_getline(fp, KS_SEP_LINE, &str) >= 0 )
+ {
+ if ( !str.l || str.s[0]!=tbx->conf.meta_char ) break;
+ puts(str.s);
+ }
+ }
+ if ( !args->header_only )
+ {
+ int nseq;
+ const char **seq = NULL;
+ if ( reg_idx ) seq = tbx_seqnames(tbx, &nseq);
+ for (i=0; i<nregs; i++)
+ {
+ hts_itr_t *itr = tbx_itr_querys(tbx, regs[i]);
+ if ( !itr ) continue;
+ while (tbx_itr_next(fp, tbx, itr, &str) >= 0)
+ {
+ if ( reg_idx && !regidx_overlap(reg_idx,seq[itr->curr_tid],itr->curr_beg,itr->curr_end, NULL) ) continue;
+ puts(str.s);
+ }
+ tbx_itr_destroy(itr);
+ }
+ free(seq);
+ }
+ free(str.s);
+ tbx_destroy(tbx);
+ }
+ else if ( format==bam )
+ error("Please use \"samtools view\" for querying BAM files.\n");
+
+ if ( reg_idx ) regidx_destroy(reg_idx);
+ if ( hts_close(fp) ) error("hts_close returned non-zero status: %s\n", fname);
+
+ for (i=0; i<nregs; i++) free(regs[i]);
+ free(regs);
+ return 0;
+}
+static int query_chroms(char *fname)
+{
+ const char **seq;
+ int i, nseq, ftype = file_type(fname);
+ if ( ftype & IS_TXT || !ftype )
+ {
+ tbx_t *tbx = tbx_index_load(fname);
+ if ( !tbx ) error("Could not load .tbi index of %s\n", fname);
+ seq = tbx_seqnames(tbx, &nseq);
+ for (i=0; i<nseq; i++)
+ printf("%s\n", seq[i]);
+ free(seq);
+ tbx_destroy(tbx);
+ }
+ else if ( ftype==IS_BCF )
+ {
+ htsFile *fp = hts_open(fname,"r");
+ if ( !fp ) error("Could not read %s\n", fname);
+ bcf_hdr_t *hdr = bcf_hdr_read(fp);
+ if ( !hdr ) error("Could not read the header: %s\n", fname);
+ hts_close(fp);
+ hts_idx_t *idx = bcf_index_load(fname);
+ if ( !idx ) error("Could not load .csi index of %s\n", fname);
+ seq = bcf_index_seqnames(idx, hdr, &nseq);
+ for (i=0; i<nseq; i++)
+ printf("%s\n", seq[i]);
+ free(seq);
+ bcf_hdr_destroy(hdr);
+ hts_idx_destroy(idx);
+ }
+ else if ( ftype==IS_BAM ) // todo: BAM
+ error("BAM: todo\n");
+ return 0;
+}
+
+int reheader_file(const char *fname, const char *header, int ftype, tbx_conf_t *conf)
+{
+ if ( ftype & IS_TXT || !ftype )
+ {
+ BGZF *fp = bgzf_open(fname,"r");
+ if ( !fp || bgzf_read_block(fp) != 0 || !fp->block_length ) return -1;
+
+ char *buffer = fp->uncompressed_block;
+ int skip_until = 0;
+
+ // Skip the header: find out the position of the data block
+ if ( buffer[0]==conf->meta_char )
+ {
+ skip_until = 1;
+ while (1)
+ {
+ if ( buffer[skip_until]=='\n' )
+ {
+ skip_until++;
+ if ( skip_until>=fp->block_length )
+ {
+ if ( bgzf_read_block(fp) != 0 || !fp->block_length ) error("FIXME: No body in the file: %s\n", fname);
+ skip_until = 0;
+ }
+ // The header has finished
+ if ( buffer[skip_until]!=conf->meta_char ) break;
+ }
+ skip_until++;
+ if ( skip_until>=fp->block_length )
+ {
+ if (bgzf_read_block(fp) != 0 || !fp->block_length) error("FIXME: No body in the file: %s\n", fname);
+ skip_until = 0;
+ }
+ }
+ }
+
+ // Output the new header
+ FILE *hdr = fopen(header,"r");
+ if ( !hdr ) error("%s: %s", header,strerror(errno));
+ const size_t page_size = 32768;
+ char *buf = malloc(page_size);
+ BGZF *bgzf_out = bgzf_open("-", "w");
+ ssize_t nread;
+ while ( (nread=fread(buf,1,page_size-1,hdr))>0 )
+ {
+ if ( nread<page_size-1 && buf[nread-1]!='\n' ) buf[nread++] = '\n';
+ if (bgzf_write(bgzf_out, buf, nread) < 0) error("Error: %d\n",bgzf_out->errcode);
+ }
+ if ( fclose(hdr) ) error("close failed: %s\n", header);
+
+ // Output all remainig data read with the header block
+ if ( fp->block_length - skip_until > 0 )
+ {
+ if (bgzf_write(bgzf_out, buffer+skip_until, fp->block_length-skip_until) < 0) error("Error: %d\n",fp->errcode);
+ }
+ if (bgzf_flush(bgzf_out) < 0) error("Error: %d\n",bgzf_out->errcode);
+
+ while (1)
+ {
+ nread = bgzf_raw_read(fp, buf, page_size);
+ if ( nread<=0 ) break;
+
+ int count = bgzf_raw_write(bgzf_out, buf, nread);
+ if (count != nread) error("Write failed, wrote %d instead of %d bytes.\n", count,(int)nread);
+ }
+ if (bgzf_close(bgzf_out) < 0) error("Error: %d\n",bgzf_out->errcode);
+ if (bgzf_close(fp) < 0) error("Error: %d\n",fp->errcode);
+ free(buf);
+ }
+ else
+ error("todo: reheader BCF, BAM\n"); // BCF is difficult, records contain pointers to the header.
+ return 0;
+}
+
+static int usage(void)
+{
+ fprintf(stderr, "\n");
+ fprintf(stderr, "Version: %s\n", hts_version());
+ fprintf(stderr, "Usage: tabix [OPTIONS] [FILE] [REGION [...]]\n");
+ fprintf(stderr, "\n");
+ fprintf(stderr, "Indexing Options:\n");
+ fprintf(stderr, " -0, --zero-based coordinates are zero-based\n");
+ fprintf(stderr, " -b, --begin INT column number for region start [4]\n");
+ fprintf(stderr, " -c, --comment CHAR skip comment lines starting with CHAR [null]\n");
+ fprintf(stderr, " -C, --csi generate CSI index for VCF (default is TBI)\n");
+ fprintf(stderr, " -e, --end INT column number for region end (if no end, set INT to -b) [5]\n");
+ fprintf(stderr, " -f, --force overwrite existing index without asking\n");
+ fprintf(stderr, " -m, --min-shift INT set minimal interval size for CSI indices to 2^INT [14]\n");
+ fprintf(stderr, " -p, --preset STR gff, bed, sam, vcf\n");
+ fprintf(stderr, " -s, --sequence INT column number for sequence names (suppressed by -p) [1]\n");
+ fprintf(stderr, " -S, --skip-lines INT skip first INT lines [0]\n");
+ fprintf(stderr, "\n");
+ fprintf(stderr, "Querying and other options:\n");
+ fprintf(stderr, " -h, --print-header print also the header lines\n");
+ fprintf(stderr, " -H, --only-header print only the header lines\n");
+ fprintf(stderr, " -l, --list-chroms list chromosome names\n");
+ fprintf(stderr, " -r, --reheader FILE replace the header with the content of FILE\n");
+ fprintf(stderr, " -R, --regions FILE restrict to regions listed in the file\n");
+ fprintf(stderr, " -T, --targets FILE similar to -R but streams rather than index-jumps\n");
+ fprintf(stderr, "\n");
+ return 1;
+}
+
+int main(int argc, char *argv[])
+{
+ int c, min_shift = 0, is_force = 0, list_chroms = 0, do_csi = 0;
+ tbx_conf_t conf = tbx_conf_gff, *conf_ptr = NULL;
+ char *reheader = NULL;
+ args_t args;
+ memset(&args,0,sizeof(args_t));
+
+ static const struct option loptions[] =
+ {
+ {"help", no_argument, NULL, 'h'},
+ {"regions", required_argument, NULL, 'R'},
+ {"targets", required_argument, NULL, 'T'},
+ {"csi", no_argument, NULL, 'C'},
+ {"zero-based", no_argument, NULL, '0'},
+ {"print-header", no_argument, NULL, 'h'},
+ {"only-header", no_argument, NULL, 'H'},
+ {"begin", required_argument, NULL, 'b'},
+ {"comment", required_argument, NULL, 'c'},
+ {"end", required_argument, NULL, 'e'},
+ {"force", no_argument, NULL, 'f'},
+ {"preset", required_argument, NULL, 'p'},
+ {"sequence", required_argument, NULL, 's'},
+ {"skip-lines", required_argument, NULL, 'S'},
+ {"list-chroms", no_argument, NULL, 'l'},
+ {"reheader", required_argument, NULL, 'r'},
+ {"version", no_argument, NULL, 1},
+ {NULL, 0, NULL, 0}
+ };
+
+ char *tmp;
+ while ((c = getopt_long(argc, argv, "hH?0b:c:e:fm:p:s:S:lr:CR:T:", loptions,NULL)) >= 0)
+ {
+ switch (c)
+ {
+ case 'R': args.regions_fname = optarg; break;
+ case 'T': args.targets_fname = optarg; break;
+ case 'C': do_csi = 1; break;
+ case 'r': reheader = optarg; break;
+ case 'h': args.print_header = 1; break;
+ case 'H': args.print_header = 1; args.header_only = 1; break;
+ case 'l': list_chroms = 1; break;
+ case '0': conf.preset |= TBX_UCSC; break;
+ case 'b':
+ conf.bc = strtol(optarg,&tmp,10);
+ if ( *tmp ) error("Could not parse argument: -b %s\n", optarg);
+ break;
+ case 'e':
+ conf.ec = strtol(optarg,&tmp,10);
+ if ( *tmp ) error("Could not parse argument: -e %s\n", optarg);
+ break;
+ case 'c': conf.meta_char = *optarg; break;
+ case 'f': is_force = 1; break;
+ case 'm':
+ min_shift = strtol(optarg,&tmp,10);
+ if ( *tmp ) error("Could not parse argument: -m %s\n", optarg);
+ break;
+ case 'p':
+ if (strcmp(optarg, "gff") == 0) conf_ptr = &tbx_conf_gff;
+ else if (strcmp(optarg, "bed") == 0) conf_ptr = &tbx_conf_bed;
+ else if (strcmp(optarg, "sam") == 0) conf_ptr = &tbx_conf_sam;
+ else if (strcmp(optarg, "vcf") == 0) conf_ptr = &tbx_conf_vcf;
+ else if (strcmp(optarg, "bcf") == 0) ; // bcf is autodetected, preset is not needed
+ else if (strcmp(optarg, "bam") == 0) ; // same as bcf
+ else error("The preset string not recognised: '%s'\n", optarg);
+ break;
+ case 's':
+ conf.sc = strtol(optarg,&tmp,10);
+ if ( *tmp ) error("Could not parse argument: -s %s\n", optarg);
+ break;
+ case 'S':
+ conf.line_skip = strtol(optarg,&tmp,10);
+ if ( *tmp ) error("Could not parse argument: -S %s\n", optarg);
+ break;
+ case 1:
+ printf(
+"tabix (htslib) %s\n"
+"Copyright (C) 2016 Genome Research Ltd.\n", hts_version());
+ return EXIT_SUCCESS;
+ default: return usage();
+ }
+ }
+
+ if ( optind==argc ) return usage();
+
+ if ( list_chroms )
+ return query_chroms(argv[optind]);
+
+ if ( argc > optind+1 || args.header_only || args.regions_fname || args.targets_fname )
+ {
+ int nregs = 0;
+ char **regs = NULL;
+ if ( !args.header_only )
+ regs = parse_regions(args.regions_fname, argv+optind+1, argc-optind-1, &nregs);
+ return query_regions(&args, argv[optind], regs, nregs);
+ }
+
+ char *fname = argv[optind];
+ int ftype = file_type(fname);
+ if ( !conf_ptr ) // no preset given
+ {
+ if ( ftype==IS_GFF ) conf_ptr = &tbx_conf_gff;
+ else if ( ftype==IS_BED ) conf_ptr = &tbx_conf_bed;
+ else if ( ftype==IS_SAM ) conf_ptr = &tbx_conf_sam;
+ else if ( ftype==IS_VCF )
+ {
+ conf_ptr = &tbx_conf_vcf;
+ if ( !min_shift && do_csi ) min_shift = 14;
+ }
+ else if ( ftype==IS_BCF )
+ {
+ if ( !min_shift ) min_shift = 14;
+ }
+ else if ( ftype==IS_BAM )
+ {
+ if ( !min_shift ) min_shift = 14;
+ }
+ }
+ if ( do_csi )
+ {
+ if ( !min_shift ) min_shift = 14;
+ min_shift *= do_csi; // positive for CSIv2, negative for CSIv1
+ }
+ if ( min_shift!=0 && !do_csi ) do_csi = 1;
+
+ if ( reheader )
+ return reheader_file(fname, reheader, ftype, conf_ptr);
+
+ if ( conf_ptr )
+ conf = *conf_ptr;
+
+ char *suffix = ".tbi";
+ if ( do_csi ) suffix = ".csi";
+ else if ( ftype==IS_BAM ) suffix = ".bai";
+ else if ( ftype==IS_CRAM ) suffix = ".crai";
+
+ char *idx_fname = calloc(strlen(fname) + 5, 1);
+ strcat(strcpy(idx_fname, fname), suffix);
+
+ struct stat stat_tbi, stat_file;
+ if ( !is_force && stat(idx_fname, &stat_tbi)==0 )
+ {
+ // Before complaining about existing index, check if the VCF file isn't
+ // newer. This is a common source of errors, people tend not to notice
+ // that tabix failed
+ stat(fname, &stat_file);
+ if ( stat_file.st_mtime <= stat_tbi.st_mtime )
+ error("[tabix] the index file exists. Please use '-f' to overwrite.\n");
+ }
+ free(idx_fname);
+
+ if ( ftype==IS_CRAM )
+ {
+ if ( bam_index_build(fname, min_shift)!=0 ) error("bam_index_build failed: %s\n", fname);
+ return 0;
+ }
+ else if ( do_csi )
+ {
+ if ( ftype==IS_BCF )
+ {
+ if ( bcf_index_build(fname, min_shift)!=0 ) error("bcf_index_build failed: %s\n", fname);
+ return 0;
+ }
+ if ( ftype==IS_BAM )
+ {
+ if ( bam_index_build(fname, min_shift)!=0 ) error("bam_index_build failed: %s\n", fname);
+ return 0;
+ }
+ if ( tbx_index_build(fname, min_shift, &conf)!=0 ) error("tbx_index_build failed: %s\n", fname);
+ return 0;
+ }
+ else // TBI index
+ {
+ if ( tbx_index_build(fname, min_shift, &conf) ) error("tbx_index_build failed: %s\n", fname);
+ return 0;
+ }
+ return 0;
+}
--- /dev/null
+/* tbx.c -- tabix API functions.
+
+ Copyright (C) 2009, 2010, 2012-2015 Genome Research Ltd.
+ Copyright (C) 2010-2012 Broad Institute.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdlib.h>
+#include <string.h>
+#include <ctype.h>
+#include <stdio.h>
+#include <assert.h>
+#include "htslib/tbx.h"
+#include "htslib/bgzf.h"
+
+#include "htslib/khash.h"
+KHASH_DECLARE(s2i, kh_cstr_t, int64_t)
+
+tbx_conf_t tbx_conf_gff = { 0, 1, 4, 5, '#', 0 };
+tbx_conf_t tbx_conf_bed = { TBX_UCSC, 1, 2, 3, '#', 0 };
+tbx_conf_t tbx_conf_psltbl = { TBX_UCSC, 15, 17, 18, '#', 0 };
+tbx_conf_t tbx_conf_sam = { TBX_SAM, 3, 4, 0, '@', 0 };
+tbx_conf_t tbx_conf_vcf = { TBX_VCF, 1, 2, 0, '#', 0 };
+
+typedef struct {
+ int64_t beg, end;
+ char *ss, *se;
+ int tid;
+} tbx_intv_t;
+
+static inline int get_tid(tbx_t *tbx, const char *ss, int is_add)
+{
+ khint_t k;
+ khash_t(s2i) *d;
+ if (tbx->dict == 0) tbx->dict = kh_init(s2i);
+ d = (khash_t(s2i)*)tbx->dict;
+ if (is_add) {
+ int absent;
+ k = kh_put(s2i, d, ss, &absent);
+ if (absent) {
+ kh_key(d, k) = strdup(ss);
+ kh_val(d, k) = kh_size(d) - 1;
+ }
+ } else k = kh_get(s2i, d, ss);
+ return k == kh_end(d)? -1 : kh_val(d, k);
+}
+
+int tbx_name2id(tbx_t *tbx, const char *ss)
+{
+ return get_tid(tbx, ss, 0);
+}
+
+int tbx_parse1(const tbx_conf_t *conf, int len, char *line, tbx_intv_t *intv)
+{
+ int i, b = 0, id = 1, ncols = 0;
+ char *s;
+ intv->ss = intv->se = 0; intv->beg = intv->end = -1;
+ for (i = 0; i <= len; ++i) {
+ if (line[i] == '\t' || line[i] == 0) {
+ ++ncols;
+ if (id == conf->sc) {
+ intv->ss = line + b; intv->se = line + i;
+ } else if (id == conf->bc) {
+ // here ->beg is 0-based.
+ intv->beg = intv->end = strtol(line + b, &s, 0);
+ if ( s==line+b ) return -1; // expected int
+ if (!(conf->preset&TBX_UCSC)) --intv->beg;
+ else ++intv->end;
+ if (intv->beg < 0) intv->beg = 0;
+ if (intv->end < 1) intv->end = 1;
+ } else {
+ if ((conf->preset&0xffff) == TBX_GENERIC) {
+ if (id == conf->ec)
+ {
+ intv->end = strtol(line + b, &s, 0);
+ if ( s==line+b ) return -1; // expected int
+ }
+ } else if ((conf->preset&0xffff) == TBX_SAM) {
+ if (id == 6) { // CIGAR
+ int l = 0, op;
+ char *t;
+ for (s = line + b; s < line + i;) {
+ long x = strtol(s, &t, 10);
+ op = toupper(*t);
+ if (op == 'M' || op == 'D' || op == 'N') l += x;
+ s = t + 1;
+ }
+ if (l == 0) l = 1;
+ intv->end = intv->beg + l;
+ }
+ } else if ((conf->preset&0xffff) == TBX_VCF) {
+ if (id == 4) {
+ if (b < i) intv->end = intv->beg + (i - b);
+ } else if (id == 8) { // look for "END="
+ int c = line[i];
+ line[i] = 0;
+ s = strstr(line + b, "END=");
+ if (s == line + b) s += 4;
+ else if (s) {
+ s = strstr(line + b, ";END=");
+ if (s) s += 5;
+ }
+ if (s) intv->end = strtol(s, &s, 0);
+ line[i] = c;
+ }
+ }
+ }
+ b = i + 1;
+ ++id;
+ }
+ }
+ if (intv->ss == 0 || intv->se == 0 || intv->beg < 0 || intv->end < 0) return -1;
+ return 0;
+}
+
+static inline int get_intv(tbx_t *tbx, kstring_t *str, tbx_intv_t *intv, int is_add)
+{
+ if (tbx_parse1(&tbx->conf, str->l, str->s, intv) == 0) {
+ int c = *intv->se;
+ *intv->se = '\0'; intv->tid = get_tid(tbx, intv->ss, is_add); *intv->se = c;
+ return (intv->tid >= 0 && intv->beg >= 0 && intv->end >= 0)? 0 : -1;
+ } else {
+ char *type = NULL;
+ switch (tbx->conf.preset&0xffff)
+ {
+ case TBX_SAM: type = "TBX_SAM"; break;
+ case TBX_VCF: type = "TBX_VCF"; break;
+ case TBX_UCSC: type = "TBX_UCSC"; break;
+ default: type = "TBX_GENERIC"; break;
+ }
+ fprintf(stderr, "[E::%s] failed to parse %s, was wrong -p [type] used?\nThe offending line was: \"%s\"\n", __func__, type, str->s);
+ return -1;
+ }
+}
+
+int tbx_readrec(BGZF *fp, void *tbxv, void *sv, int *tid, int *beg, int *end)
+{
+ tbx_t *tbx = (tbx_t *) tbxv;
+ kstring_t *s = (kstring_t *) sv;
+ int ret;
+ if ((ret = bgzf_getline(fp, '\n', s)) >= 0) {
+ tbx_intv_t intv;
+ get_intv(tbx, s, &intv, 0);
+ *tid = intv.tid; *beg = intv.beg; *end = intv.end;
+ }
+ return ret;
+}
+
+void tbx_set_meta(tbx_t *tbx)
+{
+ int i, l = 0, l_nm;
+ uint32_t x[7];
+ char **name;
+ uint8_t *meta;
+ khint_t k;
+ khash_t(s2i) *d = (khash_t(s2i)*)tbx->dict;
+
+ memcpy(x, &tbx->conf, 24);
+ name = (char**)malloc(sizeof(char*) * kh_size(d));
+ for (k = kh_begin(d), l = 0; k != kh_end(d); ++k) {
+ if (!kh_exist(d, k)) continue;
+ name[kh_val(d, k)] = (char*)kh_key(d, k);
+ l += strlen(kh_key(d, k)) + 1; // +1 to include '\0'
+ }
+ l_nm = x[6] = l;
+ meta = (uint8_t*)malloc(l_nm + 28);
+ if (ed_is_big())
+ for (i = 0; i < 7; ++i)
+ x[i] = ed_swap_4(x[i]);
+ memcpy(meta, x, 28);
+ for (l = 28, i = 0; i < (int)kh_size(d); ++i) {
+ int x = strlen(name[i]) + 1;
+ memcpy(meta + l, name[i], x);
+ l += x;
+ }
+ free(name);
+ hts_idx_set_meta(tbx->idx, l, meta, 0);
+}
+
+tbx_t *tbx_index(BGZF *fp, int min_shift, const tbx_conf_t *conf)
+{
+ tbx_t *tbx;
+ kstring_t str;
+ int ret, first = 0, n_lvls, fmt;
+ int64_t lineno = 0;
+ uint64_t last_off = 0;
+ tbx_intv_t intv;
+
+ str.s = 0; str.l = str.m = 0;
+ tbx = (tbx_t*)calloc(1, sizeof(tbx_t));
+ tbx->conf = *conf;
+ if (min_shift > 0) n_lvls = (TBX_MAX_SHIFT - min_shift + 2) / 3, fmt = HTS_FMT_CSI;
+ else min_shift = 14, n_lvls = 5, fmt = HTS_FMT_TBI;
+ while ((ret = bgzf_getline(fp, '\n', &str)) >= 0) {
+ ++lineno;
+ if (lineno <= tbx->conf.line_skip || str.s[0] == tbx->conf.meta_char) {
+ last_off = bgzf_tell(fp);
+ continue;
+ }
+ if (first == 0) {
+ tbx->idx = hts_idx_init(0, fmt, last_off, min_shift, n_lvls);
+ first = 1;
+ }
+ get_intv(tbx, &str, &intv, 1);
+ ret = hts_idx_push(tbx->idx, intv.tid, intv.beg, intv.end, bgzf_tell(fp), 1);
+ if (ret < 0)
+ {
+ free(str.s);
+ tbx_destroy(tbx);
+ return NULL;
+ }
+ }
+ if ( !tbx->idx ) tbx->idx = hts_idx_init(0, fmt, last_off, min_shift, n_lvls); // empty file
+ if ( !tbx->dict ) tbx->dict = kh_init(s2i);
+ hts_idx_finish(tbx->idx, bgzf_tell(fp));
+ tbx_set_meta(tbx);
+ free(str.s);
+ return tbx;
+}
+
+void tbx_destroy(tbx_t *tbx)
+{
+ khash_t(s2i) *d = (khash_t(s2i)*)tbx->dict;
+ if (d != NULL)
+ {
+ khint_t k;
+ for (k = kh_begin(d); k != kh_end(d); ++k)
+ if (kh_exist(d, k)) free((char*)kh_key(d, k));
+ }
+ hts_idx_destroy(tbx->idx);
+ kh_destroy(s2i, d);
+ free(tbx);
+}
+
+int tbx_index_build2(const char *fn, const char *fnidx, int min_shift, const tbx_conf_t *conf)
+{
+ tbx_t *tbx;
+ BGZF *fp;
+ int ret;
+ if ( bgzf_is_bgzf(fn)!=1 ) { fprintf(stderr,"Not a BGZF file: %s\n", fn); return -1; }
+ if ((fp = bgzf_open(fn, "r")) == 0) return -1;
+ if ( !fp->is_compressed ) { bgzf_close(fp); return -1; }
+ tbx = tbx_index(fp, min_shift, conf);
+ bgzf_close(fp);
+ if ( !tbx ) return -1;
+ ret = hts_idx_save_as(tbx->idx, fn, fnidx, min_shift > 0? HTS_FMT_CSI : HTS_FMT_TBI);
+ tbx_destroy(tbx);
+ return ret;
+}
+
+int tbx_index_build(const char *fn, int min_shift, const tbx_conf_t *conf)
+{
+ return tbx_index_build2(fn, NULL, min_shift, conf);
+}
+
+tbx_t *tbx_index_load2(const char *fn, const char *fnidx)
+{
+ tbx_t *tbx;
+ uint8_t *meta;
+ char *nm, *p;
+ uint32_t x[7];
+ int l_meta, l_nm;
+ tbx = (tbx_t*)calloc(1, sizeof(tbx_t));
+ tbx->idx = fnidx? hts_idx_load2(fn, fnidx) : hts_idx_load(fn, HTS_FMT_TBI);
+ if ( !tbx->idx )
+ {
+ free(tbx);
+ return NULL;
+ }
+ meta = hts_idx_get_meta(tbx->idx, &l_meta);
+ if ( !meta )
+ {
+ free(tbx);
+ return NULL;
+ }
+ memcpy(x, meta, 28);
+ memcpy(&tbx->conf, x, 24);
+ p = nm = (char*)meta + 28;
+ l_nm = x[6];
+ for (; p - nm < l_nm; p += strlen(p) + 1) get_tid(tbx, p, 1);
+ return tbx;
+}
+
+tbx_t *tbx_index_load(const char *fn)
+{
+ return tbx_index_load2(fn, NULL);
+}
+
+const char **tbx_seqnames(tbx_t *tbx, int *n)
+{
+ khash_t(s2i) *d = (khash_t(s2i)*)tbx->dict;
+ if (d == NULL)
+ {
+ *n = 0;
+ return NULL;
+ }
+ int tid, m = kh_size(d);
+ const char **names = (const char**) calloc(m,sizeof(const char*));
+ khint_t k;
+ for (k=kh_begin(d); k<kh_end(d); k++)
+ {
+ if ( !kh_exist(d,k) ) continue;
+ tid = kh_val(d,k);
+ assert( tid<m );
+ names[tid] = kh_key(d,k);
+ }
+ // sanity check: there should be no gaps
+ for (tid=0; tid<m; tid++)
+ assert(names[tid]);
+ *n = m;
+ return names;
+}
+
--- /dev/null
+@HD VN:1.4 SO:unsorted
+@SQ SN:Sheila LN:20
+@RG ID:ID SM:foo
+Fred 16 Sheila 1 86 10M * 0 0 GCTAGCTCAG ********** RG:Z:ID A!:A:! Ac:A:c AC:A:C I0:i:0 I1:i:1 I2:i:127 I3:i:128 I4:i:255 I5:i:256 I6:i:32767 I7:i:32768 I8:i:65535 I9:i:65536 IA:i:2147483647 i1:i:-1 i2:i:-127 i3:i:-128 i4:i:-255 i5:i:-256 i6:i:-32767 i7:i:-32768 i8:i:-65535 i9:i:-65536 iA:i:-2147483647 iB:i:-2147483648 F0:f:-1 F1:f:0 F2:f:1 F3:f:9.9e-19 F4:f:-9.9e-19 F5:f:9.9e+19 F6:f:-9.9e+19 H0:H:AA H1:H:dead00beef Z0:Z:space space
+Jim 16 Sheila 11 11 10M * 0 0 AAAAAAAAAA * BC:B:C,0,127,128,255 Bc:B:c,-128,-127,0,127 BS:B:S,0,32767,32768,65535 Bs:B:s,-32768,-32767,0,32767 BI:B:I,0,2147483647,2147483648,4294967295 Bi:B:i,-2147483648,-2147483647,0,2147483647
--- /dev/null
+>Sheila
+GCTAGCTCAGAAAAAAAAAA
--- /dev/null
+Sheila 20 8 20 21
--- /dev/null
+@SQ SN:c1 LN:10
+s0 0 c1 1 0 10M * 0 0 AACCGCGGTT **********
+s1 0 c1 2 0 10M * 0 0 ACCGCGGTTC **********
+s2 0 c1 3 0 10M * 0 0 CCGCGGTTCG **********
--- /dev/null
+@SQ SN:c1 LN:10
+s0a 0 c1 1 0 10M * 0 0 AACCGCGGTT **********
+s0A 0 c1 1 0 3M4N3M * 0 0 AACGTT ******
+s0b 0 c1 2 0 1S8M1S * 0 0 AACCGCGGTT **********
+s0B 0 c1 2 0 1H8M1H * 0 0 ACCGCGGT ********
+s0c 0 c1 3 0 2S6M2S * 0 0 AACCGCGGTT **********
+s0c 0 c1 3 0 2S3M2I3M2S * 0 0 AACCGNNCGGTT ************
+s0C 0 c1 3 0 2H6M2H * 0 0 CCGCGG ******
--- /dev/null
+@SQ SN:c1 LN:10
+sq1 0 c1 1 0 10M * 0 0 AACCGCGGTT ********** MD:Z:10 NM:i:0
+sQ1 0 c1 1 0 10M * 0 0 AACCGCGGTT * MD:Z:10 NM:i:0
+SQ1 0 c1 1 0 10M * 0 0 * * MD:Z:10 NM:i:0
+sq2 0 c1 1 0 4M1D5M * 0 0 AACCCGGTT ********* MD:Z:4^G5 NM:i:1
+sQ2 0 c1 1 0 4M1D5M * 0 0 AACCCGGTT * MD:Z:4^G5 NM:i:1
+SQ2 0 c1 1 0 4M1D5M * 0 0 * * MD:Z:4^G5 NM:i:1
+sq3 4 c1 1 0 * * 0 0 AACCCGGTT *********
+sQ3 4 c1 1 0 * * 0 0 AACCCGGTT *
+SQ3 4 c1 1 0 * * 0 0 * *
--- /dev/null
+@SQ SN:c1 LN:10
+s0a 0 c1 1 0 10M * 0 0 AACCGCGGTT *
+s0b 0 c1 1 0 10M * 0 0 AACCGCGGTT *
+s0c 0 c1 1 0 10M * 0 0 AACCGCGGTT *
+s1 0 c1 1 0 5M6I5M * 0 0 AACCGGTTAACCGGTT *
+s2 0 c1 1 0 5M1P4I1P5M * 0 0 AACCGTTAACGGTT *
+s3 0 c1 1 0 5M3I3P5M * 0 0 AACCGGTTCGGTT *
+s4 0 c1 1 0 5M3P3I5M * 0 0 AACCGAACCGGTT *
+s5 0 c1 1 0 4M1D2P2I2P1D4M * 0 0 AACCTAGGTT *
+s6 0 c1 1 0 2M3D6I3D2M * 0 0 AAGTTAACTT *
--- /dev/null
+@SQ SN:c1 LN:10
+s0a 0 c1 1 0 10M * 0 0 AACCGCGGTT *
+s0b 0 c1 1 0 10M * 0 0 AACCGCGGTT *
+s0c 0 c1 1 0 10M * 0 0 AACCGCGGTT *
+s0d 0 c1 1 0 10M * 0 0 AACCGCGGTT *
+s1 0 c1 1 0 5M6I5M * 0 0 AACCGGTTAACCGGTT *
+s2 0 c1 1 0 5M1P4I1P5M * 0 0 AACCGTTAACGGTT *
+s3 0 c1 1 0 5M3I3P5M * 0 0 AACCGGTTCGGTT *
+s4 0 c1 1 0 5M3P3I5M * 0 0 AACCGAACCGGTT *
+s5 0 c1 1 0 4M1D2P2I2P1D4M * 0 0 AACCTAGGTT *
+s6 0 c1 1 0 2M3D6I3D2M * 0 0 AAGTTAACTT *
+s7 0 c1 1 0 4M2D4M * 0 0 AACCGGTT *
+s8 0 c1 1 0 5D2P2I2P5D * 0 0 TA *
+s9 0 c1 5 0 1M2P2I2P * 0 0 GTA *
--- /dev/null
+@SQ SN:c1 LN:10
+@RG ID:p.sam SM:unknown LB:p.sam
+s0a 0 c1 6 0 5I6P5M * 0 0 AACCGCGGTT * RG:Z:p.sam
+s0b 0 c1 6 0 5I6P5M * 0 0 AACCGCGGTT * RG:Z:p.sam
+s0c 0 c1 6 0 5I6P5M * 0 0 AACCGCGGTT * RG:Z:p.sam
+s0d 0 c1 6 0 5I6P5M * 0 0 AACCGCGGTT * RG:Z:p.sam
+s1 0 c1 6 0 11I5M * 0 0 AACCGGTTAACCGGTT * RG:Z:p.sam
+s2 0 c1 6 0 5I1P4I1P5M * 0 0 AACCGTTAACGGTT * RG:Z:p.sam
+s3 0 c1 6 0 8I3P5M * 0 0 AACCGGTTCGGTT * RG:Z:p.sam
+s4 0 c1 6 0 5I3P3I5M * 0 0 AACCGAACCGGTT * RG:Z:p.sam
+s5 0 c1 6 0 4I3P2I2P1D4M * 0 0 AACCTAGGTT * RG:Z:p.sam
+s6 0 c1 6 0 2I3P6I3D2M * 0 0 AAGTTAACTT * RG:Z:p.sam
+s7 0 c1 6 0 4I7P1D4M * 0 0 AACCGGTT * RG:Z:p.sam
+s8 0 c1 6 0 7P2I2P * 0 0 TA !! RG:Z:p.sam
--- /dev/null
+@SQ SN:c1 LN:10
+@CO Tests permuations of seq / qual being present or "*" in mapped
+@CO and unmapped forms. Also tests MD/NM tag generation.
+_sqm 0 c1 1 0 2M1I4M1D3M * 0 0 AACCCTCGTT IIIIIIIIII MD:Z:4G1^G3 NM:i:3
+_sm 0 c1 1 0 2M1I4M1D3M * 0 0 AACCCTCGTT * MD:Z:4G1^G3 NM:i:3
+_m 0 c1 1 0 2M1I4M1D3M * 0 0 * * MD:Z:4G1^G3 NM:i:3
+_squ 4 c1 1 0 * * 0 0 AACCCTCGTT IIIIIIIIII
+_su 4 c1 1 0 * * 0 0 AACCCTCGTT *
+_u 4 c1 1 0 * * 0 0 * *
--- /dev/null
+>c1
+AACCGCGGTT
--- /dev/null
+c1 10 4 10 11
--- /dev/null
+@SQ SN:c2 LN:9
+@CO
+@CO mpileup example from https://github.com/samtools/htslib/issues/59
+@CO with additional Pad cigar operations
+@CO
+@CO c2 CC***AA**T**AA***CC
+@CO
+@CO +s1 CT***AA**T**AA***TC
+@CO +s1b CT*******T*******TC
+@CO +s2 CT*****G***G*****TC
+@CO +s2p CT*****G***G*****TC
+@CO +s3 CT*****GG*GG*****TC
+@CO +s3b CT****CGGCGGC****TC
+@CO +s4 CT***AAG***GAA***TC
+@CO +s4p CT***AAG***GAA***TC
+@CO +s5 CTGGG*********GGGTC
+@CO
+s1 0 c2 1 0 9M * 0 0 CTAATAATC XXXXXXXXX
+s1b 0 c2 1 0 2M2D1M2D2M * 0 0 CTTTC *
+s2 0 c2 1 0 2M2D1I1D1I2D2M * 0 0 CTGGTC *
+s2p 0 c2 1 0 2M2D1I1P1D1P1I2D2M * 0 0 CTGGTC *
+s3 0 c2 1 0 2M2D2I1D2I2D2M * 0 0 CTGGGGTC *
+s3b 0 c2 1 0 2M1D1M2I1M2I1M1D2M * 0 0 CTCGGCGGCTC *
+s4 0 c2 1 0 4M1I1D1I4M * 0 0 CTAAGGAATC *
+s4p 0 c2 1 0 4M1I1P1D1P1I4M * 0 0 CTAAGGAATC *
+s5 0 c2 1 0 2M3I5D3I2M * 0 0 CTGGGGGGTC *
--- /dev/null
+>c2
+CCAATAACC
--- /dev/null
+c2 9 4 9 10
--- /dev/null
+@SQ SN:CHROMOSOME_I LN:1009800
+SRR065390.14978392 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 AS:i:-18 XS:i:-18 YT:Z:UU
--- /dev/null
+@SQ SN:CHROMOSOME_I LN:1009800
+SRR065390.14978392 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+SRR065390.921023 16 CHROMOSOME_I 3 12 100M * 0 0 CTAAGCCTAAATCTAAGCCTAACCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA ###############################################???88:;98768700000<>:BBA?BBAB?BBBBBBBB>B>BB::;?:00000 XG:i:0 XM:i:3 XN:i:0 XO:i:0 AS:i:-6 XS:i:-13 YT:Z:UU
--- /dev/null
+@SQ SN:CHROMOSOME_I LN:1009800
+@SQ SN:CHROMOSOME_II LN:5000
+@SQ SN:CHROMOSOME_III LN:5000
+@SQ SN:CHROMOSOME_IV LN:5000
+@SQ SN:CHROMOSOME_V LN:5000
+I 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+II.14978392 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+III 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+IV 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+V 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+VI 2048 CHROMOSOME_I 2 1 27M100000D73M * 0 0 ACTAAGCCTAAGCCTAAGCCTAAGCCAATTATCGATTTCTGAAAAAATTATCGAATTTTCTAGAAATTTTGCAAATTTTTTCATAAAATTATCGATTTTA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
--- /dev/null
+@SQ SN:CHROMOSOME_I LN:1009800
+@SQ SN:CHROMOSOME_II LN:5000
+@SQ SN:CHROMOSOME_III LN:5000
+@SQ SN:CHROMOSOME_IV LN:5000
+@SQ SN:CHROMOSOME_V LN:5000
+I 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+II.14978392 16 CHROMOSOME_II 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+III 16 CHROMOSOME_III 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+IV 16 CHROMOSOME_IV 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+V 16 CHROMOSOME_V 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 XS:i:-18 AS:i:-18 YT:Z:UU
+VI 0 CHROMOSOME_V 10 1 7S20M1D23M10I30M10S * 0 0 AGCCTAAGCCTAAGCCTAAGCCTAAGCTAAGCCTAAGCCTAAGCCTAAGCTTTTTTTTTTCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA *
+VI 256 CHROMOSOME_V 10 1 7S20M1D23M10I30M10S * 0 0 * *
--- /dev/null
+@SQ SN:CHROMOSOME_I LN:1009800
+S1 0 CHROMOSOME_I 1 255 36M4I33M2D18M4I13M3I5M2I7M1I8M4I30M1D20M5D25M4D63M1D31M2I13M4I83M3I36M4D77M2D8M2D5M2D14M2I5M4D1M1D27M5I3M4D47M2D5M4D7M1I70M3D42M4I59M5I2M2I13M4D3M5D6M4I5M4I58M1I10M3I57M1I15M5D57M4I10M1I19M4D9M3I27M4D11M3I9M4I21M4I62M4I51M1I8M3D23M1I5M4I24M2D1M5I4M4D14M3D63M5I1M2I20M4D10M5D7M2D22M4I22M2I9M3I46M5I1M4D12M5D8M3D17M5D149M1D20M1D61M1I14M2I38M4D9M4I62M1I8M1I55M3D62M4I8M4I50M5D19M3D11M2I53M4D7M2D32M2D57M3I48M2D11M4D15M1I23M2D16M5I7M1I3M1D27M5D4M1I18M1D79M5D1M5D8M5D20M1D22M5D24M2D30M5D43M1I17M1I22M2D18M3D1M4I15M1I4M3D1M3I22M5D62M4D19M3I3M5I7M2I110M5D7M2I9M4I28M2D3M4I17M1D1M5D103M5D45M3I32M3I37M1D20M1D22M5I6M3D101M1D20M3D6M1D15M5I14M5D118M1I3M1D3M5I37M4D10M4D10M1D10M2I48M1D2M3D7M4I60M1I38M4I16M3I20M4I30M2D3M2D15M3D35M1D7M1D1M1I44M4D6M5I1M2D2M3I83M3I3M1D18M2I1M5D65M2I13M3I25M1I10M2I23M2D12M1D10M1I1M4D8M3D27M5I9M1D11M3I69M4D115M1D28M5D38M4I5M5D21M4I11M5D43M4I70M5I38M1I27M2D8M3I2M2I10M1D94M5D17M2D9M4I21M1D2M5I8M2D32M4D52M1I37M3D7M5I64M1I31M2I21M2I11M4I46M4I5M5D22M1D55M4I18M3D102M5I72M4I4M1I7M5D19M1D40M2D101M3I2M1I36M2I26M4D5M2I29M5I13M5I20M3I9M2I8M2I143M1I10M4D25M5I41M1I9M5D12M2I8M4I11M2D66M3I1M5D77M5D4M2I49M4I15M3D11M4D17M5I143M2I29M4I4M3I4M3I19M3I44M5D108M3D12M2D19M1I13M3I18M5I2M1I16M1D4M3I318M4I39M4I21M1I24M3D32M2D70M5D11M5D34M4D46M4D3M3D32M3D54M2I8M1D65M5I53M5I27M3D6M1I34M5I34M5I37M4D1M5D10M5I68M1I8M4I6M1I14M5I6M5I26M3D50M2D2M5D22M4I34M1D24M1I28M4D67M2D43M4D17M4I57M3D35M5I66M1D45M2D27M3D28M3I32M4D24M1I16M2I3M3D6M4I33M4I12M2I19M2D5M1D119M3I64M5D29M3I87M2D4M4D42M4D3M4I76M2D19M2I51M2D18M1D2M4D21M4D11M1I6M4D135M1D10M1D120M1I102M4D37M5I8M2I51M4D50M2D14M2D32M5I2M5I36M4D59M3I87M1I21M2D14M1D27M5I3M5D4M4I90M1I37M5I19M3D12M1I21M5D51M4D3M4I8M4D28M4I76M2D5M3I13M4I214M4I18M1I22M2D12M2D123M5D9M1I9M2I17M1I7M5I70M2I34M1D13M5I2M2I69M4D129M5I64M2D15M2D9M1I56M5D73M1D45M5I55M3I26M2I24M4I31M2D29M5I2M2D80M3I28M1D19M4I1M5D4M3D118M3D36M2D32M3I1M2D35M2D27M1I32M2I7M3I51M1I51M3D21M4I4M5I40M1I27M4I55M1I16M4D50M1D107M5D96M1I4M1I68M4I4M4D4M1D78M1I5M2I73M1D7M5I21M4I8M5D71M5D19M5D20M2D7M5D27M1D35M5D38M4I83M1D33M4D54M4I19M1I3M2I11M4I4M1D10M5I24M3D1M2D12M4D8M5D1M2I22M2D39M2D101M4I4M4I26M5I13M3I26M4D33M5D10M2I13M3D19M3D18M2I27M2D3M2I2M4D33M3D55M4I6M3I129M1I14M3D41M4I3M5I81M5D9M5D12M2I5M3D1M5D40M5D2M1D21M1D4M2I2M4I12M4I22M3I105M4I1M5I14M3D19M5I6M4I13M2I10M2D11M4I34M2I7M2D32M3I13M5D23M4D8M3D59M5I11M3I53M1D19M2I122M2D15M2D108M5I1M4D14M5I11M4D12M1I19M2I1M3D7M3D4M2I1M5I24M2I15M1I36M3I16M3D25M5I3M4I22M5D6M4I22M3I77M5I43M1D13M3D30M5I19M4I29M2I86M2I23M4I9M3I7M1I14M3I3M4I39M1I77M2D5M4D58M1D1M1D4M5D57M5I22M3I84M1D19M3I14M5D21M4I10M5D17M1I4M4I63M2I23M4I23M4D32M5D40M5I29M4I126M3I2M1D105M4I49M1I32M4D29M5D31M1D15M5I6M5I21M4I56M2I6M3D11M4D3M1D28M4D78M1D5M1D20M3I67M1D2M2I7M5I2M4D14M5D4M3D27M2I18M5D20M5D58M3D19M4D36M5I133M3I75M4I39M3D28M3D158M4D8M2I12M5I68M5I18M2D17M4I52M1D90M5I17M5D47M4D3M2I15M3I4M1D17M4D1M3D23M1I84M5I1M4D10M1I11M3D78M2I3M4I2M5D13M5D21M2D24M1I89M4I2M3D59M4D22M5I14M4I16M2I53M1I13M1I81M4D11M3I29M2I170M2I43M5I116M3I1M5D1M2I20M5I51M1I17M3D2M4I5M3I17M5D36M5D21M3D4M2I85M2I18M2D42M3I48M3I7M4I11M5I17M4I3M3D45M1I93M1D38M5I8M2D41M3I56M2I35M5D59M5D36M3D9M5D23M4I12M4I14M1D38M5D6M1D2M1D2M3D126M1I9M2D31M5I81M4I7M5D19M5I25M3D222M2D29M2D105M1D39M1I4M2D7M2D67M3D32M5D3M3D36M1I50M2I117M1I75M1D24M2I80M4I48M1I11M4D4M2D55M4I21M5I29M1D51M3D16M5I43M3I17M3I6M4D99M3D17M3D22M3I18M5I35M3I28M1I23M4D9M1I46M3I16M4D18M3I32M3I16M1I60M4D76M3D1M3D9M2D28M2D25M1D8M1D1M5D56M3I8M4I33M1D15M2I83M5D60M5I99M4D90M4I69M4D41M1I4M4I1M3I50M3I38M2D80M2D56M4D33M3I8M2I11M5I15M3I42M1I135M2D29M1I34M3I13M1I74M1I10M5I48M4I8M2I74M4D6M3I43M2D3M4D99M2D20M3D35M5I12M1I4M2D25M5I68M3D57M3I24M5D8M5D10M3D84M5I170M3D31M1I9M3I7M2I47M1D31M4D7M4I13M2D7M4I7M2I58M1I81M3D18M5I6M5D68M4I18M1D25M2D1M2I7M4I5M1I14M3I75M2D33M5D17M1I19M2I3M5I5M5D53M3D1M3I33M1D27M5I33M1D93M5D1M3D167M4D38M2I33M3D119M4I43M3I31M3I7M1I77M5I5M2D5M5I24M4D10M4I88M5D47M4I29M4D63M1D11M2I41M3D97M3D13M4D48M3D55M4I3M5D32M1D53M5D13M1D7M2D23M4D131M4D17M2D18M4D4M2D6M1I71M1I29M5I12M3D48M1D45M4I41M1I84M5I84M2D17M5D87M3D88M2D14M5I52M5D62M4I39M2I44M2I26M4I15M4D21M1I8M3I21M4I48M4D34M4D29M4I17M1D18M5I91M1I35M4D4M2I10M4D26M2I4M1I27M4I14M2D11M3I35M5I64M2D86M1I119M5I23M4D27M4I70M5I8M1D12M3D17M3I9M1D77M3D29M1D35M1I37M3D7M4D35M2I13M3I9M2I112M1D19M4I20M4D81M5I129M1D3M4D48M4D31M4I73M5D18M4I8M2D15M5I18M4I33M5I112M3D13M2I26M5I21M3D1M1I63M2D1M3I22M5D5M4I18M2I10M3D7M1I34M3I1M4I2M5D56M3I48M4D13M3I26M5D24M5I7M5I13M4D16M5I44M1D60M1I17M2D18M5I4M2I1M4I4M4D40M5D81M2D19M3D4M1I19M4D10M4I9M5I7M2D51M2D13M4I19M1D57M2D58M3D84M3I2M1I24M1D11M1D3M3I47M2I9M2D5M2D65M1I25M2I35M3I45M3D1M5I13M1I34M3D5M5D2M4D30M2D21M3I6M1I69M4D69M1D9M3I61M4I3M4D16M4D47M3D28M3D14M2I85M2I33M4I9M4I48M4D78M5I73M2I5M1D60M3I31M4D1M5I24M2I32M4I14M2I19M3I5M2D22M2D49M3D5M3D11M2D43M4D4M1D10M1I14M3I3M5I19M5I63M3I4M3D32M4I1M5D18M1D17M4D41M3D25M1I20M3D43M2I21M2I19M3D2M3D17M4D30M5D30M4D9M4D6M3D51M4I58M2D23M2D4M1I19M1I12M2D20M2I1M3I42M2D82M3I3M4D33M2I37M5D65M1I82M4D6M1D54M5D11M5D34M4I7M3I17M5I33M5D38M1I31M5D26M1I16M4D20M2I13M5I23M1I11M1I10M4I4M3I7M3I26M3D30M5D3M4I35M3D1M5D14M4D24M3I23M4I7M1I32M1D29M3I14M1D107M5I6M5I6M4D3M1I41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53M1I23M5D33M1I25M5D4M4D43M3I41M4D6M5I75M4D61M2I39M2D58M4D56M1I19M2D4M5D103M3D30M2I19M4I10M1D6M2I20M2D10M5I42M5D5M4D61M1I97M4D6M4I71M1I71M2I28M2I5M4D6M5I39M1D9M3I33M4D6M4D28M5I37M2D22M2D97M5D9M2I63M5D8M5I14M2D2M5D15M5D55M2I155M5I95M2I48M3I15M3D5M3I6M3D56M5I13M4D3M2I10M5D4M1D72M2I24M5D1M3I18M4I103M2I37M3I53M5I14M5I20M2D47M2D26M3I50M4D11M3D3M1I86M2D45M2I53M1I48M1D3M4I4M3D2M1D12M2I51M2I6M1D22M3D24M4D43M4D16M5I1M3D4M5I74M4D10M5I7M4D12M5D25M2D133M3I136M5I1M1I2M4D1M1D64M1I12M4D48M2I48M3I57M1D56M1D3M3I54M4D21M5I68M4I32M1D21M4D46M5I14M4I8M3D20M5D15M2D175M4I10M5I10M4I15M4I46M2I3M4D5M1D23M5D26M3I29M5I9M5D31M3D22M5D13M3I29M2I74M4I12M5I71M3I97M1D10M2D106M2D23M3D5M4D37M4D13M4D95M5D6M3I6M1D22M5I29M4D9M5I43M2D2M1I30M4D18M5D46M2I25M1D14M4I23M4I3M4I21M1D20M1D5M1I19M1I65M1I5M1I3M4D74M5I66M1D40M4D4M5I60M4D21M3D2M5D11M1D12M3D9M4I41M2I54M4D14M4I12M2I8M2I5M1D12M3I14M3I4M2I60M5I19M2D10M2D7M5I42M5I12M5D7M5D104M3I22M2I11M5D17M2D11M5D24M5I2M1D89M4D12M3I66M4I12M2D19M2I115M5D47M3I7M4I26M1I42M5D83M2D4M3I27M5I66M3I87M1D42M4D13M2I28M2D11M1I49M1I1M4I29M2D41M1I4M1I23M1I4M2D3M3D78M1D35M2I13M2D52M4I51M1D135M4I97M2I20M5I12M3D80M3I35M2D25M1D14M4D73M4D9M3D37M5D14M4D13M1D49M1D29M5D59M4I13M2D10M3D17M2I11M4I5M3D44M3D47M5D36M4I2M3D28M4D96M3I39M2D25M2D42M4D68M2I65M5I123M5I25M4D15M5I53M2I40M2D15M3I31M1I5M5I45M1D1M1D19M4I4M3I32M5D20M4I73M4D4M2D44M3I20M2I73M3D10M4D7M1D2M2D5M1I10M1I176M2D20M2D80M2D22M3D103M3D67M3D60M1D45M3I11M3D10M4I29M4D20M2D26M1D27M1I61M2D3M4D31M3D36M5D54M1D83M3I34M2D7M2I30M5D93M5D8M4I18M3I96M1D19M3I8M5D29M3I33M5I76M4I40M2D4M2D1M3D4M2I19M2D3M1I10M5I57M5D38M3D32M4D3M2I8M1D9M5D204M5I19M5I21M5I21M3I5M3I12M4D34M1D1M2I19M1D13M2D4M5I6M2D34M1D37M2D11M2D58M3D8M3I10M3I30M4D4M5D58M3D29M3I15M2I21M1I26M1D69M4I10M1D46M4D12M4D8M5I29M2D7M5D1M3I104M4D27M4D34M4I20M5I22M3D51M1D2M5D21M4D16M3I148M5I47M4D16M1I18M2I12M3I95M4D8M5I13M1D89M3I57M5I5M3I31M3I117M2D69M3I8M3I16M1I62M4D39M4D50M5D36M2I6M5D122M3D43M1D42M5I23M1I48M3D47M1D23M1I38M3D59M5D3M3I12M1D8M3D46M1D25M1I2M3I6M2D15M2D6M4D11M1I39M4I57M4I21M1I20M2D61M5D52M2D52M1I4M4D29M1D15M3I66M3I7M5D11M2I25M2D25M4I68M3D40M4I49M3D134M4D44M5D18M3I14M1D1M3D7M1I19M2I8M5I19M5D51M2D11M2I20M2I33M1I6M1D9M5D3M3I91M2I11M3I15M3D66M2D5M4I2M2D3M2I78M4D13M5I6M1I26M4I34M3I76M5I7M3I120M4D48M1D75M2D18M2I40M2D23M5I3M2I40M1I18M5I23M5D15M3D32M1D21M4D46M3D42M5D95M4I5M2I53M5I16M4D36M3I69M1I73M1I17M4I9M3D20M5I9M3D24M4D84M5D13M4D88M4I20M3I1M4D4M4I42M4D17M5D20M2I13M4D17M1D27M4D61M3I25M4I6M5I10M1D26M2I38M5D64M3D92M2I33M3I50M2D77M1I27M1I8M3D16M3D8M4I33M5I97M1D41M3D18M2I21M5D44M4D41M5D6M4I8M4I12M2D8M5D10M3D73M1I31M1I17M3I6M4I2M4I39M5I26M1I61M1I13M2I42M1D43M2D19M5I6M5I16M2I31M5I27M1I7M4D2M1D3M2D83M5I5M2D27M5D23M4I10M3D69M1I1M2D56M2D15M3D65M2D23M3I10M3I25M5I65M1I8M5D5M5I255M4D3M1D91M3D40M5D3M3I17M4I106M4D27M4I10M5I7M1D31M2D32M1D51M2D36M1D12M4D3M5D3M1I74M4I110M3I9M4D20M4D4M4D18M3I20M3I44M2I1M1D10M2I17M3I48M5I7M4D27M1D29M4I6M4D9M5I40M4D32M1D86M1I1M2D6M4I21M2I27M5I11M2D22M2D21M1I31M1I123M3D29M3D23M3I13M1D23M5D6M4I11M3I38M2I16M3D5M1I26M5D15M4I116M4D9M1I4M5I20M1D61M2I15M5I7M1I35M1D68M5I13M1I17M1D22M2D1M2D80M5I37M3D5M4D5M1I43M4D13M2D13M2I22M2I75M5D17M5D8M2D41M3I53M2I17M2I9M2I109M2I3M4I39M2D82M2D39M3D31M2D55M4I11M3I17M4D32M1I1M1D35M3I1M4I45M5D75M1I92M1D58M2I16M5I4M3I9M4D2M5I117M2I30M3I14M5I5M1I12M2I8M1D1M3D38M3I28M5D71M1I38M4D105M2D18M3D8M4D89M4I17M4I25M2D5M4D19M2I37M4D44M4I25M3D6M4I45M4D35M1I3M5I29M1D28M1D17M3I10M3I115M2I50M3I6M3D58M4D20M3I34M3D25M2I13M5D15M2D59M2D78M1D4M3D55M2I43M4D1M3D13M3I39M4I4M1I34M2D16M5D133M4D15M1D63M1D29M2I9M1D16M5I45M3I35M1D15M2D50M1D24M4I3M5D9M3I4M5D40M1I33M1I10M3D8M1I28M1D34M5D128M5I7M2D55M1D112M5I1M3D23M2D17M4I3M2D91M1D44M1D20M3I31M5I5M2I6M3I38M5I27M4I37M4D47M1I17M3I13M4D21M4I12M5I20M1D37M1I17M5D35M5D21M1D9M2I21M1D21M5I6M5D294M3I23M2I24M2I9M3D33M2I1M1D4M4D39M4I27M1I7M5I8M3I35M2D3M4D31M2I52M5I9M4D42M2D45M4D33M1D2M1D17M5I96M3D10M3I28M4I4M4D25M1D2M1D42M3D12M4D4M2I29M5I33M3D11M5D21M3I58M5D3M3D33M5I1M3I47M3I42M5D7M5D8M3I12M1D1M5I6M3I159M2D5M1D38M1I2M3D42M2I77M5I30M4D2M4D3M5I1M3I30M4D25M3I24M1D26M2D26M3D21M2I4M5D16M5I36M4I22M2D10M2I210M2I19M5D41M4D7M5I85M2I29M5D105M3I31M3I3M4D5M3I5M2D19M5D83M3I34M3I6M2I7M5D61M3I102M3D9M1I27M2I20M3I30M4I6M5D5M3I9M5I83M5I35M2I1M2D78M3D7M1D45M5I43M1I11M2D3M3D14M2I68M2D66M1I7M2I2M2I3M4D18M3D29M4I6M1D9M5I13M5I13M3I47M2I24M3D2M3D9M4D9M1D64M4D29M1D11M4I56M3D3M1I56M3D102M3D28M3I23M3D52M4D126M3I44M2D33M3D162M5I22M3D54M5I43M3D18M4I56M3I18M1I5M2I39M1I11M5I60M5D22M2I18M2D76M1D50M3I31M1D49M3D116M3D60M3D24M2D25M5I10M4D1M3I29M2D103M1D8M2I67M1D46M1D2M3D65M2D26M3D4M3D14M1D10M1D15M5I27M4I8M3D9M4I21M4I28M5I38M2D10M5I2M2I18M5D8M1I4M2I22M5I85M3I32M2D3M3D14M1D15M5D68M2I3M4I51M4D2M3I4M2I24M4I4M2I10M2D7M1D51M3I1M1D1M2I23M1I2M4I5M5D6M4I33M1D75M2D7M1I25M2I4M2D33M4D35M5I70M2D50M5I22M3D79M2D28M4D9M5I16M1D26M3D19M3D57M1I87M5D12M3D111M3I18M2D47M5D2M4D6M4D9M5D42M1D112M4D8M3I54M2D1M3D41M5I8M1I14M1D15M3I6M2D5M5D14M2I15M2D8M3I4M5I19M5I45M3I39M5I15M4I25M2I18M4I10M1I105M2I7M5D27M4D3M1D1M1I16M4D2M2D21M3I6M5I68M2I31M1D61M4I23M2I14M2I8M1D105M2I13M3I20M3I52M3D61M5I8M4D7M4I14M1D15M1I11M1I12M4D25M3D1M1D31M5I5M3D1M3D83M2D27M4I14M1I1M1D21M1D45M4D58M1D3M1I50M5I8M4I67M4I25M5D18M4D60M1I11M2D33M4I4M3I2M2D48M1I110M4D2M3D29M3I2M1D48M5D14M4D62M3D45M5D21M3I18M1I17M1D5M4I31M4D58M4D35M5I27M3I4M5D93M5I155M5I16M5I53M1D27M2I2M4I17M3D34M5D32M2D64M5I20M2D52M1D33M1D83M5I6M1I40M5I3M5D37M5D3M4I37M5I6M5D1M2I99M3I28M2I23M2D4M1D121M1I50M3D30M2D1M2I80M4D20M5I45M4I64M4I20M4D17M2D8M2I51M2I32M1D14M4I3M2D143M1D3M5D1M1I36M3D1M1I64M5D47M4I8M1D12M2I43M1I119M3D61M1I106M3I27M5D3M5D71M1I18M3I1M1D20M2D29M5I32M4D10M5D18M3D31M5D77M4D10M5D27M5I26M2D6M4I43M2D43M1D15M1I6M3I71M3D65M4I40M2I27M4I17M2I95M5I7M2D177M3D47M5I3M2I4M3I24M3D10M4I38M1I45M1D11M2I40M2I15M5D77M3D41M5I130M2D34M1I32M3I13M3D23M3D18M1I21M2D55M * 0 0 GCCTACGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAATATGCCTAAGCCTAGGCCTAAGCCTAAGCCTAAGCCAGCGTCAGCCTAAGCGTAGCTCAGCCTAAGCCTAAATGGCCTAGGAGCCTAATGCCTAAGCTGAGCTAAACCTAAGCCTAAGCCTAAGCCTAAGCTAAGCTTAAGCCTAAGCGTAAAGCCTAAGCCTAAGCCCAAGCCTATAAGCCGAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTCAGCTTAACCTAAGCCTAAGCCTAGGCCTAACCCTAAGCGTCTAAGCCTAAGCCGTAGTAAGGCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTATGCCTAAGCCCAAGCTCTCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAAAGAGATAAGCAAACATTTTATTTTTTCAAAATTGTTTTCATGGTAAATTCAAAACGTTTTTTTTTTAGTGAAGCTTCTATATTTGGGGTACCTAATTTTGCCTGCACCTGCCTTATGCTCCTGTGTTTAGGCCTAGTACTTGTTTAAGATCCTAAACCTAATACTAAGTCTAAGCCTAAGACTAAGCCTAATACTGCCTATAAGACTTAAGGCTAAGACTTAGCCTAAGACTAAGCCTAATACCAAGCCTAAGCCTAAGACTAAGCCTAAGCCGAATAAGCCTAAGCCTAAGACTAAGCCTAATACTAAGCCTAAGCCTAGAACAGACTAAGCCTAAGACTGAGCCTAAGACTAAGCCTTATACTTAGCCTAAGCCAAAGACTCAATGAATAGCCTTAGCCTAAATATCTACAGCCTGAAACGCCTGGTAGTACACTCTTCTGAAAATACAAAAAATTTGCCATTTTTATAGCTAGGGCACTTTTGTGTCTGCCCATCTAATATAGGCAACCAAAAATAATTGCCAAGTTTTTGATGATTTGTTGCATATTGAAAATAAACATTTTTCGGGTGAAATGAATATCGTAGCTACAGAAATGGTTGTGCACTCATCTGAAAGTTTGTTTTTCTAGTTTGTTTTCTTCGCACTTTGTGCAGAATTCTTCTTGATTCTCATTGCAGAAATTTGCAAGAAAATTCGCAATTTGTATTAACAAAAATTGTTCAGTGAAAATTTTTGGAAATTAGTTTACGAATAAATCTCACATTTTTTATAGAAAAATTATTTTTAAGAATTTTTCATTTTAGGAATATTGTGCGTTATTTTAGAAAATAGCTAAATGTGATCTCTGTAATTTTGCCTGCCAAATTCAGTGAAATGTAAAAATCTAATATCCCTCATCACGTGCGACTTATTCCCGAATCAGCAAATTTTTTCAATATGATAGTTTGACATCAATAATTTGCCTATATAACTTTAGACCTGGAGTTGGCTATTAATGCCAAATTCATGATATCTAGCCACAACATTCGTTAGTAGAATTGTTGTTAGTGACGAACCTATAAACAGATTCGTGTTTTCAAGAAATTTTGCTATCATGGTTTTTCTTGGTCTTTTAACCTGGTATTTCGTTTTTGACAAAAATTTTTGTTTCTTGATTCTTGCAAAAATTTTTCCCTCACGACGGCCTTGATGTACCTTCGAAATACTACATCTTCTGGTTCTAATAGTGTTCATTGTTTTATATAAATACTTATTTAATAGGATTTCGGGTTATATAATTTGTATAAAGAGTGGTTGACATAACAAGGCTGACGAAACTTTGTGATGGCTGAAAATATTTTCGTAGCTTTGTTGATTTTTATTTATCGTGTTTGAATAACGTGTCCAATCGCCGAGAAGGAATAGAATACTGGACGACATTGTACGTATTATCCAAAAAATCAGAAAGGTAGATGACGGCACCACAATTCTTTCTGTCAGGTTTTACAACCGCCCAGTGCGTGTCACATGTTCACTGTATAAATGGTTGTACACAATATGCGGAAATAATCTAATGCATTCCAATAAGGCATAATATAAGAGGCTATCAGGCAATGCGTATCGCTCTTTGCTTTGTTTAAAGGGGGAGTAGAGTTTGTGGGGTCTATGTTTCTGAGTCTAATTTTGCCCCTGATACCGAATATCGATGTTAAAAAATTTAAAAATGTCAATTTCCCTCAATGATTTTATATTATTTTTTAAAATCCGAAATTCCATTGGATGCCTATATGTTCTAAACGCAAAATTTTCGCAGAGACCCCTGCCGCCCACGAAACCTTGCCGCACGTGTGGGTTTACGAGCTGAATATTTTCCTTTTTTATTATTTTATACCGATTTTGGTCGATTTTTCTCATTTTCTCTTTTTTTTGGTGTTTTTTATTGAAAATTTTGTGATTTTCGTAAAGTTATTCAAACTATTTATTAATAAAAACAAAAACAACTCCATTAAATATCCCATTTTCCGCAAAAGCGAAGACTAGGAAAATCGCTCTGGAGATAGAATGGATCAACAATTCTTATTATATCATTCCGCTAAAAATCATTATTAATTTTCTTCTGAGAGTCTCATTGCTTAGTTTACGCCAAGAAATAAATTAAAATTAAAATTGTTCATTTTTGAAAAAAAAATAATTAAAAAAACACATTTTTTGGAAAAAAAAATAACTAGAAAAACGGATCCTCCGCGTCGAATCACTGTTTCCGAACTCTTAAAATTCAATGTTTATTGTACAACCCTTTCGCTATTGATTTGATAGCTTTTAAGTAATAGAATTTTCGATACATTAAAACATTTCACAATTAAGCTGGTTCTGAACTGTGTAGAAGTATATTTAAACAAGACTAACTGATACAAAAATATAATTATGATAGTTTTCTGGACCACGCCAATATAAACGATGATCAATCAAGGGACCTGCTACAGTCGTCCACTAACCCGAATATCGACAAGAAAAGAAGAACGCCAACTTTGGATAGACGCTCTAGGGGCCGATGTCGGAAACTAGTCGGGAAGCTAAACCAGAATAGAGGGTACATTACAGATGAGGAGGAGGATGAAGATAGAAATATGCCGACAACATCGTCAGGCCGCTGATTTTTTTGATGTTCTACGCTTAAATTTTCAGCGAACGAACTATTTATTTTGATTGCCTTTTTAAATTTATAATATTTGCCATATGAAATTCTCACTTTCAGGCTGGAAACGTAGTTTTGCAGGCCCCGTCTCCAGTCGATTTTGCGCTGAAAATGGGATATTTAATGGAATTCTTTTTGTTTTTGTTAATAAATAGGAATAAATTTGCGAATATCACAAAATTTTCAAAACACCAAAAAAAAAGAGAAAACATGAGAAAAATCGACGAAAAATTTCGCTATAAAATCAATTAAAAATAGAAGGAAACATATATTCAGCTCGTAAACCCGCAAGTGCGGCACGGTTTGTGGGAGGGGCGGCTCTGGCGGAAAATTTTGCGTTTGAAAACGTCGATTACATGGCATCCAATGGATTTTCGGATTTTCAAAATTAATATAAAATCAGGGAAATTTTTTTAAATTTTGTCACTTCGATATTCGGTATCCGGGGCAAAATTAGAGCAGAAACATAAATTTCCCCAACTCTATCCCCCTTTAACAACCAACGCACCCGAGGATATACAAGCGTTCTATCTACTAGGCATAACTCGATTATTGACATATTATAGACTTCTTTTAATATTTGTAAAATAGTGGATCAGACCCAAAATTCAGCCCGCGAAGGCATGACGTCAGCACGGAGGAGTCTTGTAGTTTCCAGAAGAACTCTGTCGTCTACCCTAATGCCTTGCGAACCCGGGCCATCCTTTCGCTCAGAGGAAATGGATTAGAGTACTCATCAACTCCTCTGTCTAATTTTCAACTGCGGGGGCGACCGTACTGTATTACCGCGGCGACCGACACCTCCCGCGTTCCGTCGATCGCTGTCTGTTGTGTGCGCCTGCGACTCCGCCCACCGGTGGTAACTTTTTGTGGAGGAACAATTCCTTGATTTTGGTCAAGGTTTTTCTGCGCTTTTCAGCGTATTATTATTGACCAATTTTGAATAAAATTTTCAAGAATCATCTAAAATATTTAACATTTATTTAACATAAATAACGTGAGTACGCAGTAAAACTTGACATTTTCAGGAAAATTGCAATTAAACGAATAAAAATCGATATATCCATCATGTTTGGTCGTGAATCCGGTGTGTTGAGCCTACAATGCATACATTTTTACTGGATAAATCTCCTTTGGGAATCCGGTTTGCAGTGCTTTCGAAATGACATGTCCAGTTGAGAATCGCAGGCTCTAAGATGCTCGGGCTGAATAATGAATTGTTTTAAAAAATGTTTAGTAAAAAATTGTTTTCGAATGCATATTGGCTTAACCGATATTATCCAAACGTGACGTTTTCGCGATTTTCGCGCGCTAAAATTACAGTGAGTGAGGTCGACACGACAATTTTGTAAAATTACGGGCGTTCTTTAAGAAGTACTTTAGTTTAAAAAATACACTTCATTTCGTGGAATTTTCTGAATATATTTTTCATAGTTTTTCTCTTTAAATAAATCACTTTTCAACAAAAAACTATGAGACAATAGTTTGTACAGTATTCTTTAGAGGGGCACGCCTGCTCGAATTTCGCAAAAACGTGTCGTGTCGAGACCCCCATTACAGTATTTTTGAGCCGAATATCGCGAAATTTCAAGTCTGGGTGAAACATTGAAATTTTTGGCAAAATAAAAGAATCCTCTTTCAGAATATATTTTGTAAATTTCGAGACGAAATGTATACCTAAATGAATTTTAATTTTAAACCCCTATTAAATATTATTTGGCGTTTTTTATGCATGTCGATTCACTAACGATTTAGTAGTAACTACACGTGGGCAAGTTTATACAGTTTTTGGCTAAGATTTGTGAATTTGAACCGTTTTTCGGCGAACATTACACATGAAAAATTGGCAAAACGGGTTCAAAAACAAAAATTTTGTTAAACTGTAAAAACTGTCCAAAAATTTCGTAAATAACCGGCACACACCCTTTCATTTTTTCAAAATTTTAATTGTTTTCGAATGTTTTTTTTGCAGAATAATTTGTAAAATGAGCCTTTTGTGAATTTTTTTTAATTTCAAAGTTTATTTTTTCTCAAACCAACCCCTGTTGTAACTCGTCCAACTATGATCATCACGTACTGTCGAATAAGTTTCTCGTGATTTGTCACATTATCCTTGAGCTACATCCGCCAGGTTTCAGTCCTTTCTGAAAATGAAAATTAATTTTAAACAATATTGAATTATTTTAAATGAAACAGTTTTCAGAGATTTAACCTTTCGTTCGAGTCCACCACCAGGCCTGCACGTTATTCGGGTGTTATCTTTTAAAAAACTGAAAAATCGAAAATAGTTCAATTTCTGTTTTGTGGTCAAAATTGTTCAATTACAGGTAAGCAAATAGTCTTTAATTTTCAAGTGAATTGAAAATTAGGGAAATGACCGGACATAAGTTTAAAAACCCGATTGCAGTTTTCAAAGGTAAATTGAAAATTTAATAAACAGGTTGTAAATCAAGGAGATCCTATTGAATGAAAAAAAATCCGAATGTGCCGACGGGATTTTTCGGTGGTTTTTGAACGAAAATCGAAAAAGTAAATGTTTTTAATTTTCAAATTTCAATTTTTAATCGGAAAAAATGTACGAAATTGACTTTTTCATGTGAAACATTGTTGTTTTCTAGTAAAAAAAAATTTTAACCGATACAGATTTTCTAGACTCAGTTTTTTCGGTTGAATATTGTTTTTTACTATTTTATCTTTCTATTACAGATACAATTTTATTTCGCTTAAAAATAACCGGAACATCGAAAATATTTTTTTTTCTGTTTCTCAAAACATTTCAATTACCTAGAATTTTGTTTAAAAACTACATGCTTTATTTATGAACGTAGTAAATAATACCCCCTCTTATTTATAAACTTTCAACATACAATTTTTCAGTTTTCAGTGCTATCTAGTGCTTACCGCACATCACTTTTAAAGAAATCAACCAAATCGTCACCAAATATGCCCTGAAATCCATTGAATCCATAACAACTTTAATCATAACGTCGTTCGTTTCGGGCGGTGCAAACGTCTTTGGCAGTCCTTCGCTACGAATCATTATCTCCAATTCGTGGATGTTTTCCAATATATTGATCACTTTTCGTGATCAACTCCTCGACAACTTCTTCCATATCAACTTTCAATAAGAATGGCATTAAGAGATGCTTTGTAACACGTCCGATACCCGCTCCGCAGTCCAGCTGCATAGTCAAGCCGAATAGATTCTGGAAAATATTGTCATTGTAAAATTCAAAGTTGGCCCAGGGGTGACCGGCAATTTCACAGCAAATCGTTGTCAATTTTCCATGAATTTGATGCCCGAAAATTGGAAAAACGACAATTTGCCGGTTCGCTGAATTTACCTTTTTTAAATTTAATTTTCAATTCAGGCAAACGCTTTTTTCCGTTTGCCGGATATCAATTTGCAGGAATTTCTCAAAGGAATTTTTATTAAAACGGAAACACAGTGCTTTTTTTTTTCTTTCCCGTGTTTTTCAGATATTTTTATAAAGTTTACTGACTTTTCAGAATGGTGAGATGTAGGACAATTTTGTTTTAAAAAAATTGTGAAATTTCCAGCAGAACAAAAAAACATGTGCAAACCCACAAGTTGGCAAAAATATTTTGCATTTGCCGTTTTTCCCGTTTGCCGAAAAGTCTAATCTCGGTAATTGCGCCATTTTTCGAGATTTTGAGCCACATAAAAAACTTTGAACCATTTTTGAGTTAAGTATTATTACGACATTCGTTTATTTGACGCTGCACGAGAATTTTATGGGCCTATACCTTCAAAATTGTCGGGGTTTGAAAACCCCTATATGTTCGACCGAATGTTAATCTCACTTTGATGAAAATAAAATTTTCTACGGCTCATAAACGTATAGCCGCCGTCAGTCTCAAAATTTATACGATAGACACTTTATGGCGTTTATCGCCTATATTCCGTCAACAATTATTCATCTCTTTCAATGTTGTTTTTTTTTAAGGCTAAAAATGAACTTTCATGCAAATTTGTTTGATTAGGCCGTGTCGTGGTTCAACGATGCAAATTTCAGAATTTAAAAAATAAATGAAAACGAAAATGTTTCTATATACCCTATTTGTGTTCTGTGATTCCGAATACCACTGTGAAAAATTCAAAAAAAATGCCCTGATTTTATATAAATTTTTGTAAGCGTCTACAATTGTCGTTTGAATATCACACTTGGTTACACAAAATTATGAAAATGAGGAAAATTTGTTTTAATTTTTTCACATTGATAGTCGGAATCAGGAAAAAAAATAAGGTCTATAGAAAAATTCCGAACCTTTACTGCTTCTCTGGGTATAATAAATTTAAAATAAATACAGAAAATTTCAGTTCACACTGACCTAATTAAATTTGGGTATATTTCTAGGATCCGAGTTCTTGTTTACACCAGATTTACAAACTATCTAGCCTTTCACCGCCTTTTTATCATTTCCCTTCAGGCAACTCCATAAAAATCGCCTTTCGCCTCATATTACAAGATTATTCCCCTTTCTCTCCCCATTGAAAGTCATTTTCGAAACAAGCGGAAGTCATATGTGGTGTGGTGTGCGTTGGCAAACAACAAGAAAGAATCTCTGAAAACAAAAAGCGTTTTGGGTGCCCAAGTAATATTGAAAATCGTGTCTCATTTTCCATCAAAAGAAAAGGAGAAAAATTCGGCGTTTTGTTTGATTTCCGGGAAAGAAGACTCGGAAAAAGATTTAATTGACTATTTTTCAAGCAAACCTATATTGCTACAACTTTCTAAAAGGTCAGAAATTGCCGCGTAGCCTAGAAAATTGGAGGTTTAAACTCTTCCAGCTGGTAGTATTTCAGACAGGGTGCATCGAAAATTCGAAAATCCTCCTACAGAAATTAACATTTTGAAGCATCTAGAAAAGTTGAGATTATAGTACCTCACTTTTGCCGAGAAATCTCTTTCGAGGTTGAAGAGGTCTTACAAAATTTTCGGTCCTCTGACGTGAAAATGGGATGGGTTAAGGCTTCACACGACGGCGTTTTCAGGTCACACGAGAAGTTATCGTACGAGGAGAATTGACCTCCAAACCCTGATCGTGACTACAGGTCGTCGTTCGGAGCATGCGGAAGGTTCAGTGTTCGAAAATCTTCGACCAGCTTATGAGACCAGCGAAATAGACAGGACGACCAAACATTTGTGGAAGAGCTTTTCCTAGACCATCAGGATGCTATTTCGACAGAGCTGAGATAGTCGTTACGAAGTGTGGAAAAGCTGGTTTTCCAAAATCCCCGACCAGGTAGAAAATGAGACACCGATTAAGTTTATCCAGTGGGTAGAGTTTTTTCTAGGCCATCATTATGCTAGAAAAAAGCTTCGGCCATGGGGTTTTTAGGCCGTCTATTTATTTCTCATCACTTTCTCAGAAATTTCTATTTCTCAGCACCCCCCAATGATAAGTTTTTTGCAAAAAACTGCTTTGCTCATCAGCAATTCGTAATCAGGTGACCCCATTAGGCCTACCGAAACACACATTTGTCATTATTTTTCCGAATAACAAGAAAAAAGTCTTCACGCATGGGGAGATAAGAAAACCTGATTTTAAATCTTACTGTGCCGGCTGGCGCGGCGAGCTTCGATCACTGAGCCGAAAGATTAGAAAACTATGGGAATGAGGGCGTATCGTACAAATCGTCCAGGCAGAATCTGTCTAATTTTCGAACGTATATCCAGTTTTGTTATTAATTTAAGTAAACCCGTCAAACCTAGAAACAAGTAAAACGGGAGGGGGGGAATATCAGAAAATTAAATCTTGCGCACACTTTTCCATTGATCTACTAAGGTATACAATGCCCAGAGGTGTGCGGCAAATTTTGAAACTTACCCGCGCATGCCGCCCGTTTTTTTGTTTCTAGAAAAGTCAGATTTTTTGTCGAATTTGTTCAAAATTCGCTAAGATACTGTGAGTTTAGAAAAAATGACGAAAAAACTCGGAAAAGGAGGAAGAGATCTGAAATATGTAGATTTTTTTAGAAAAGACCAGGATAAATTACTGAAAAATTGGCATTTTTCGTCGAAACCCCAATATACTAAATTATGCGGATTTTTAGTTTCAAATTCAACATACAGTGCATTTTTTGGGCCTACTTCTACGACTTTAAAGGGGGGAGCATTTATGCGGGAGGGTCCTGCCGCGCATTTAGTCATCATTTTTAGCAGTTTCTGTGTAATTCAGATCACATGCAGGTCACACAATATTTATCCCATATTTAGTATGTGCCGTGCTTTTTCACAAATTAATTGTGATCTACGCGTGATCCCTGCGAATTTTGAGAAGACTTTGTTAAAAATGATGACTGTCCACGGCAAGACCCTTCGACGTATGAATGCGCCCCCCTTTAAAGTTGTATAAGTGGAAAAAAAATGCTCTAGCAAAAAATCGAACATTCTGATATTTGAATATCTCGAAATTAAAATAATTTGTGAAAAATTTTTATTTTATTTCGAAAACTACCGATTTTAGAAAAATTCTAAAATTTCGATTTTTTTTGTTGATTTTTCGATTTTTAAAATAAAATTTCATAATCTTTTAAACCGATCTCTCTTGCATTTCCTGAAAAATCGTGATTTCTATCCTTTTTCTTCAGTCCTTCAATAAATCGTTTCGACTCCGATAGGTCGGGCGCGTGAAGCGCTTCGAATCCGCCTAGCATTCCGTTGAAGTCCTGCCTCGCGCGGCTCCAGTATTCCTCCGCCCTGAGAGAGAATAGTTGAAAACATTGTTTTGAGACTTAAAAATTTTTTTTTTAGTTTTTTTCAAAAATTCTTACATGTTATAGAGTTTGTTTTTCAAATTTCTTTTTTCAGAAAAACTTAGTATTTTCGATAATTTTAGTTACAATAAAAACGAGTTTTTTTTCAAAAAATATTTCGGTTTTTTTTTTAATTTTTGGTCTAAAACCGCAAAAGATTTGCGTGTTGGCCGAACTTTTTGATTCTGTACCTTTTCAAACAACTGCAGCATTGAATTTTAGAAGATAATGAAGAGCTCATTTTGCTTATGCTCCAATGTTGCGTCAGCTGCTCCGAGCAGTCTGGAGACATGACGAAAAGACGAGGGGTCACGGATATGATGACGATACTGGAAATGAGATATTTACATTGTCTACTAGCTCATCGGGAAAATTATTACCAGAAAGATAAACAGACATGTGCGTTTTTTTAATGGAAGAGAAACACAAGAAAAATTTGGACAAACTAGGGCAGGGCTATGAGTCGATATATGGCTTCGGTCTCGACACCACTATTTTTGTTAACTAATATGGTATGGTCGCACCTATAAAGAGTACTGTAGTTTCTAACTCTCTTTGCTGCAACATAATTGACGCTCAGCGAAAACTACAGCAATTCTTCAAAAGACTATCTGTACCCTTTGTGTGGACTTACGGGCTCGATTCTCGTGCATAAACGAATTTCTGCTCGAATGATAGCCCTATGTCAATTTGGTATAGTCTTTTCTTTTGCCATTTTTCCGTGTTCTTCTAATATTTAATCTATTATTAAATTATGTAATTCTCACCCTCCTTAGAACTGCGACCGAACAGAGATTCGTCACCTCCGCCCCATATTCCGGCCAATCAGATCGAGTAGGCGGAGTTCGAAGTCGCTGATTGGTTTGAAAAGTCGCGGAAATGCAAGAAGTTTTAAGGTAGCCGTGGAAAACTGATGACTATTCTAGCGCGCTTGTGTCGATTTACGGAATCTCGATTTTCAGGAAGGAATTTTTAATTACATTTTTTCGCTCAATTAATATTCTAAATAAATAACTACATGATTTGAATTAATTTAATTTCATTCGAGCCAGTAGATCGACACATGTGCTACAGTAATCATTAGTTTTCGCAACGAGATATTTTGCGCGTACAATATTTAGTGTCCCGTAATAACTCTACTCCCTACAAACATTACGACCTCCAGAGGCCTCCAGGTAGTTGAGACTCTTGTATTTCCAATTCAGAGACAATGCGTCACTGGAAGAGAAACCGAAGCGGAAAAAAAAACACGGAAACCCAAAAATAGGGTTTGCCCCGCCCTATTCTTCTCCAATAATTGTCTTATTTTTGCAAGACTTACCACCTGTGTATGCCTTACTCGACATGCGTTAAACCCCCCCCCCCCTCCCTATCTTACAAGGTACTGATAACACTTTCAGTCTTTCACACTTTTGGCGGGGACATCGCCGCTCTTTATTCGCGGCGAGCTGATGACTCATCAATTTTTCACTCAATTCCGCTTTTGATTATCTTCAATGTTCTAGAAGGGCACATTGGTCATCCTTATTTTTTCCTTCTCTTTCTCGGGCCTTTGTTGCGCATGACCGCCCCCTACAGCAGGGCGTGGCCTGAACGGGGGCTCCGAGAGCTACTCATTCTTGCCGCGTCCCCCTCCAGCGCCACCCAAACTTCTTCGGTTCTAGAGATCGAGAAGAAGCGAACGTATGATTTTTTAAAATTATAATTGTTTCTTTCGAAAAAAAAAATTTCATTTACAGTAAGCCACAGATACAATCAACGAAACTCTTGAATTCTGCTATCTTTTCTTGCGACAGTTGCGGTTTTTGGTGAGTTTATGCTTTAGACTTTTCCGCCAAAAATACAGTTGCCGGTCTCGGTATGGCAAAATTTTTGTTAAATTCGAAAAGCAGTGAGTAAGTAGTTTCGAATTTTCGTTCCTGCTTAATTTTCATCAATTCATCGACTCATTTTTCTCACGACTTCTTCTTTATGAAAAATCAATGAGAATTCTGACTAGGTCAGGATCTTAGGGGTGAGGTACCTAGGGACGCATCACATATGCCAAACGGAAGCTGAGAGCAATCATTGGCTACAAAAATATGCTTTCAAATTGCAACGGACCTCTGGGAGACTGCAAATTCGGCCATTCTGAAATTATGCTTTTGTATGCTCGAAAGTGGTAAGAATTTAGGATTTATTACAGAAGAACGTTTAATTAGTAAAATTAGTTTTTTTATACTTGAAACAAGTACAGTAGGCCTGTATCAAAACACATTGTTGGACTTCTTATTCTACTTCATGTTTTTCTGTAATAAATTCTAAATTCTTACCACTTTCGAGCATTCAAATGCATAATTTCAGACAAGAATTTCCAGAGTCCCAGAGGTGCGTCGCAGTATTTGAAATATTCTTGTAGCCAATGATCTCAGCTTCTGTTTGGCATGTGGCGTCTCTAGGTACCTCACCCCGAAGCTTCTCCATTCCCTAGTGAGCAAACAAAATTTTGAAATTAGTACGATTTAAAGGCACATTGATTTTTCTGGGTCAAGCACAAATTTGTCGTGTCGAGACCTAGGCTACGTTAGTATTTTCGCGAAAAATCGCAAAATCTTGCAGCTGGGATATACTTGTGCGAGAATACTTTTTGCATTAATTTTGAGAAAAATTATTTTTTTTAGACTTTTTGACAAAATTTTTCGGATAGCCAATCATAAAACGGCGACCTGTGCCCGGTTGTTACATTAGGCCAACAAAGTTCCTGGGAACACTGCTGCAAACCATAATAGAGGGGTCCGGAGCATAATATCGATTTTTCGTACTTTCCTGTATTTCTTGTTCTATATGGCCGGAGTAGAACAGGATTTGAAAGTCAAAATTTTTCTCATATGGATATCACATGGATATCAAAATATTTCCATATGGATATGGAGAACATTTTTCTCCTAGGGACTTTGAAAGTTGAATCACTTGACATCTGGGGAATTAGTATTCCAGGCGTAAGTCGAATCTGTTAGAAACGGAAATGGGCATAGTGAATTAGGTAGACTTTCAATTAATCTGATCCATTGCAGTCAGACGCGGTTTCCCGGCCTGACGCCTGCCTCCAACATGCCCGCCTTCACGGCCGGTCCCGCGCCTGATTTCTGCACTGTGACGAGACAGACGAAGGTCGCCTTCTGGCGCCCGCATGGAGCACAATCGAATTGTCAGCTTCCGATGGGAGTCCGTAAATCGACACACAGGGGTACCTCAGACATTTCCCTCCCCCTTACGAATTGTTAGTGACAATTGGAGGGGGACTTCATCTCCAATCGAGACACACATATGTTGTCGTCAGTGAAGTGTAAAGATCTTAACGATTGCTGTATGATGTTAAAAAGCACTCTATGATCACCTAGGTTTTTCATCACACCCTTATTAGGTGTGGTGCCCATCGAGCACTCACGCCAGGCAGGGAGAGCACCGGTCCCTGACTAATGCGAATGTTTTAGACCGGAAAGCGATGAAAGAGCATAGAAGATCATTATCACGTCTAATTAGGTTACGGCGAAATTTGCAAAAAAGAGCAGGAAACTTGGCTCATATCCAATATAACAACCAGGACTTCCATGTAGGCGTTAAAGCGATACCACTGTATCTCACCCCAATCCGTACCTTAAGCTGAAACAAACGTGGACTTTTTTCATCTCTTAAAGGAGTTTCGTAAACGGGAAATTGTTTTAAAATGGAGTATTTGTACTTCAACAATTATTGCAAAAGAAAAACGGAAAAAATCCGCTAACATTCAGCATTTTAAGTCTCATGAAGAAGTCTTTAAAATTTCAACCGTAGAGAAATCCTGCATAGGCACGACGCTCTAGGCATTCGAATTTTAATATGTTTTGATGTTTTGAGAAAAATAATACAATAACTTCCCAGTTTTCTATAACTTTGAGAAAAAAGCGAATTAAATTCCGAAAAAACTACATTTATCAATATTTTGTTTACGAATATGGCCTAGAAAGCGCGTGGTGGCCTCGGATTCATTTGCTCGCGAAATTCAAATTCCGTCACTTTCGTCGATTTCAACGGCCCTGTAAACCCGTGCTGCATGTCAACGGATTTTTCCCGCTTATTCTTTCTTTTGCAGAAATAATTAGAAGTTTGAGTACAAATACTTGTAAAACAATTTTATTTTTGCTATTTTGACGTTGATTGATTACGGTTTTTTTGGTTTGGGACCAAAAATTCCAGAAATGTTTGGCGTGTCTAGTCTTTCGACTCGAGACTACTCTGTATTAAATAGGCAAACATTTATTTTAACACAGTTGTGACGTCATAATATTTTGATACATTTTGCAACATTACTTAAATAACCCCATTAAAAATTAACCTAATCGTGCATCAAACAAAATTTTATGGTTTTTTTGGTTTTTCGAAAATTTCAATTTTTTTTGTTTTTTGGGTTTTTTTGGTTTTTCAAAAACTTCAATTTTTTGTTTTTTGGTCCAACATTTTTTTTTGGTCTCAGCTCTTCTGGCCTACCCTAGGAGAAATAGCGCTTCAAAAACTGATGAAAACGTACAAATTTGTCGATAGAAACCAAATATTACGAAAATCTGAAAAGTTGGCTCAAATCTAGATTGGATCGGCCGATTTTCCACAAGTTTCCAAGCTTCCACAAGTCGTATCCCGAGTCGATTCAAATTGAGTTTGAATACTGCCAATTTTGAACCAAATTTCCCTGGCTTCTCTGTTATTTAAAAAAACGCGAGGCAAAAAAATAAAACGATCTAATTATTACTTTTGTGAACACAAAATTCTGAAAATCGCGCGTAAATATTGCGCAACATATTTGACGCGGAAAATATCTCGTATCGAAAACTACATTAATTCTTTAAATGACACGCTGTATGTGGTTATTTACGGGCTCAAAAAACCGACACGTTTATTTTAGAAAATGCCCGTAAATCCACACATAAGAGAGTAATTGAATATAAAAAGAATTAACCTGTAGTTTTCTACGAGATATACGCTTTGCGCGCCAACTATGTTGCGCAATACGCAACCCACCATATGGATATATACTGATGTGAGGATAAAAAACAGCAAGCCAACTTTCAGCGGTCGGCTCCGGCAGGCCTCGAGGACTGCGTCCTCAGGAGCAACTGTACAGTCTGGAGAAAGAGAACGGAGTTGATGTGAAGCAAAAGGGGCGCTGAAACCAGCAGCAGATGCCGACACATTCCTTGGATTTGTTCCATAGAAGAGAATGGTCACGTGGCAGCCATGCAGCGGTCGATGATCAATATGAGGAGTCTAGAGCTCCTTGTTATTTAGTGGTGGTGGCCGTAAAAGAGAAAACTCGGCCAAGCTGCTCGGAGTTTTTGAATTTTTGATAATCCGAAATGAAAATTGATTGCTCGAAAAGGCAATCTTTTGGAAAAACGAATTTTGTAATTTTTTTCAGCAAAAATTGCTTTTCGAATTTTTCCATTAAAAAATCGATAATTTCTCCCCGTGCAGTGGAAAACAAACAATATTTTTTTGATGATTGGCACTCTTCCAAACCCGGCGAGGACTAGGTACACTCCTGCGTCATCCCCATTATCTTATCACACTTTCTTTCGAAAATAGCGTTTGAGGTAGAGACGGAAAAGTGAGAAAGGTGAGTCAATTTTATGCGTAGATTTAGGATGATAATACACACAAATTAAAAAAACGAATGCGTGGCGTGCACTGAAACCCTCATATTTAGGCCCCGCCTAACGGTTTCACCTCTCGTCCACTCACGGAGAAAAAAATTTACGTGGGGACCAACCAATATCAGGCCTAGGCCGCCATCGTACGGGTTCCGCGCGCCGCTATGTTTAACTCTCTGTGGGTGTGGCGAGCTGTCTCCGCCCGCTGCGACTCGAGTAAAACATAGCGGCGCGCGGAACCCGTAGGAAGTCGACGGCCGATATTGTTGGACAAATTTTTTCCTTTTATCCGTCAGTGGACGACTATACAAAAAGGCGGGGCCTAACCACTTAAGATGTTTTCTGCAGTACACGCCACGAACAGTTTTTTTATGTTGAGTGTATAGGTCTAGATTCTCGAAAGTCTAACAGTTATTTAAATGATGAACTCGTGATGACTGTTAAATTGCTTTGGAAATTTCGGGGGAATTATAGAAATCGATTTTGTATCGATAAGATTTACAGGAAAAACCCAGTACCACTAATATCTAGGTATTCGATGGTAGGCAGGCGCGATTTCCTTGAGGCCTGCCTGGAATCTGTCCGGCTCACACCAAAATATGTCTATCATTTTGCTGAAAACCAAATTAAGAAATGAAAGTGTAGAGATGATGACGGAGGTCGCCTTAAGGTCAGACAGGTTAAAAAACCGATTTTAGCTATTTTAATTTTCTTAACAACCGAATTAGAAATATGCTGCTTGTCATTTTTGAGTAAAAATTATTCATACGAAAACTTCGACCAAAACCACCCCGAAAAAAATGAGGAAAATAAAGATTTTTCGAGAAAATAACAAAAAAATCCAGCAAATAGTGAAAAATAGTTCTCTCCGAGAAAAGGAGTTTAGACGCTATGAGGTAGTCTCGAAAATCATTTCAACCTAAAAGCCATAAACGGCATTATCGATTAAAATTCTCACTGAAAATCCGGTGCCCGAATTTCAGTGCTCCCCACAATCGAAGCCCGCTTGGCCGAAGTGTTGAGAGCCGGAGAACGCGGCTCGGAGTCAACCCGGAGGAAGTCCGTTTTGACGGATCTTCGTCCTCGTAATTCCAATAAATATTCTTTGCCCTACATACTTTATCCATCTGACAACTAAAATGTCAGTTCTTCTTGGCTTCAGCGGTTCTATTTGTCAAATGGTTTATTTTCCCCAGAGCGAACTCTCAAAAGGTTAAAATATTGTTCGATTACCCCTTTTTGTCAATTATTTTCTTCAATTTCTTATTTATCATTATTTTTCTAAACGAAGACGGTTGTGAATTTAAATTATGTTAATGGTCTAAACTTTCCAAACTGAATAAATTCAGCATGTTGGCACGTTTTTACAGTAGTTTTTGAGTGAAAATAGAGGTAAAAAGACAGAAAATCAATAAAAAATGAAAACAAAACTATCAATGAAAAATGGTTGAAAATCGAGCAAAAATCGTTCAAAAAAAAATAAATTCGAAAAAATAATTGCGTCGAGGAACGCGTCAGTACTCTCTGCGACTCTCACCCTTCAGCACGCGCGCCACGAGAAATGCGCAATGGCTAAATTCGCGCGGAAAATCATTTCGTTTTTCAACATTAAACAAATTCGACGAGTAAATCGCTCAATACTTAAGTAAGTATGGATTTTCAGCTCGTTCAAAAAATTTTCAGAACCGTTTTAAAGTCGTAAGGTTTTTTTTTAAATCGTCGGAAGTAAAAAAATAGCGCGGAAATCTACGGAGTGCGGAGCGAACACAGGCGCTGTAATTCAAATGGGTAGAATAGTCAAAATTGAAAGTTCGCCAGCACGACCATATTTTCAAAACTTAATGGTAGATTTTTTCGTTTTTCTTTTGTGGTATTTCGGCATTTAAGATTAGAGAGCACATTTTAAAGTAAAATTCCCCATCCAAGTCGCACTCACCTTCTCCAGCCATTTCCAATTGGAAAAGTGTATTATATCCCGTCTTTTTTTTTCTGAACAATAAATTTTTCGTTTATCCAGGATAGTCATGATACAAATTCGTTAACAAAAAATGAATAAATGAGAGCGATTAAAGCATTGTCGGAAAATATGGGTTAAGGAGAAGGGGGCGGACTTTTGGATGGGGTACAAAAACCATCAATATGCAAAAACTGGGCTAAAAGCAATATTTTCAAATTATGCCCGACAAAGGTTCAAAAGTCAATATATAGAAATGAGAACATGAGTATTATGCCACGTGGCGGGAAAAATACGTGGAGTGTAATACGATGATCAGATCCTTGTGAATACAAAGTTTGTGACGACGTGGCCGAGAAGAACTTTGTAAGCCAATGCGTAAAAAGGGGTTCAGTCTAGGCCGAAATTTTTTTTGGGCCACATATTAAGTTAAATTAATTAAAAAAAATCACAGCGTATCCAATTTGCCGAGTTTTGACTTGAGCTCGGCGCGATACGTGTCGATTGACTCAAAATATTGTTTTTTTTTATTTCCGAATAAAAAATGGTGAGTACCTCCAAAATTAGCTTTTCATTGTCCATATAGAACTTTTTGATTTGTTCCACAGTTTTTGTGGCCATCCGGCGATCCAAACTCGAAATTGTCATTTCCTGGTACCAGTGGAAACCTGAAGGAATTTCGGATGTTTTTGCTTAATCATAATCATGATAATCTTACGTGAAACATAAGACTTGGAAAACGAGATTTTTCGAGAGTTCGAATTCAATTTATCTTCAGATTTTATTGCAACAAATCAATTTTCAACATAAAATAATTTTTCCAACTTTTTTTCCCAATTTATGAGAGTTTAAACATTGTTTTAAAGCAAACCGCCAACATTACATAAAAAATTAAAATATTGTTGAAGGAAAAAAATGATGAAATAGATTTTCTGACAAAAAATTTAATTTTTTTGGATTCGCGCTTCAATTATTGCGTTCTTTAAGAAGAGTGATCGAATTTTATATTTCCAATTGTAAAAAAATTTAAAATGGAATGAAACCTTTCCAAAGAAAAACTGAATATCACCAGAACTTGTGATTTTTCAGCATTTATTTTTAGGTTTGAATTTTTTTTTCATGATTGCCAAACGTGAAAAGTGCAATTTTACCGAACATTTAAAAAATCAAGATTTTTCAATTCTCTCTGAATTCCTGCAGATTTTTCGATGAAAAATTGAATTTTCCTTGGGTAATATTATTTTTCGGGAATTTATCAGTTTTTAAAAAAAATTTTATTGTCTCTGAAGTTCTCGATAAAAAATTATTTTCTGCAAAAAATCTACTTTTTCTCATTGAATATTCCGTAAAAAAAATCAGAATTACAAGGCACATTTCCTTTTCTAATCTACCGTATAATAATTCAATATTCTTTTAAAAATTCGGGGTAGATAATGAATTGTACCAATTTTTATTAAAGTTAATTTTTCTAATTTACGTTTCAAAATTTTCTTGAATAGTTTTTGGAATTACAGATTGTTTCAAAAAAATTTATTTTGTTTTTTTTTCTCGAAAATTTGAAATCCATACATTCTAATAGCATTCTTTCTGTTCCTCAGGACTCCAAACATAATTTATCCTGACCTTTCCAGATCGATTGCCATTTGTTGCAATAGTATCTAGTTCAGAAATCTCTCGAACCATCTTCCCTTCAACGCCATAATATGTTTCGCTTCCAATTTGCATTTTCTCCTTTTGGTACACGGCTGTATGTCATTGGTGCACGGAACATTGGTTGACGGGCTTCTTCATTCAGAATTCTGGAAAAGTTGATGTTGTGCGATTTTTTTTGGGTAAAAAAAACAATTTTCGTAAGTTTAATTAACTAATATTTTAAAAAATCTGTCTCAGTTTCTGAGGCACCACGGGTTCAAGATCTGGTGGGATTGCCTCCCGGATCTGGCACCGTGCCAACGCATTGAATGCAATTTTTCTGAAAAAAGGGCAACGAAGATCCGATTTAAAAAAATTTTTCAATTATTTTCCAAAGTTTTCACGAACTATAAGAACGGAGCAATTTTTCACAAAAATTCCAGTTCCTTTTTATGTTAGAATTTAAAAAAAAAATTGAATTTTTCCTAAAAAATTAGTACATTTTCCGATATCTCAAGTGTGCCATAAGAGCCTAAAATCAGAAAACTTTTAAAGGAAAAATTTTGAGCATTCTTATCAAAAAATCAACTTCTTCTCACAATGTTACCTTATTTTCTTTCTAAATTCTGAAAAGCATATCTCAGCTTTTGCTAAACTATTTTTTACCTCAAATTTTGAGAAAATTAAAATATAAGAGCTATGATATAGTAAATATTTTATTTTCTAATAATTTTTGGTATTTCTATTCTTTCGTTTTTTCATTTTTCAAAAATTCCACATAGTTTTAAATGTTCATATTATTTCTTTTGTCCAGGAAAACTCGTAAATTTTAGTACAACTTTAAACCGGAAGATTGATCTTTTAAATTTTTTTTTCAAAAAATTTGAATCTTCGACATGAAAGATGTAGAAGTGTGATTTAAAAATAAAAGTGCAGGTATTTTCAGTTTACAGCAAAAGTCAGTTTAAAAAATTTCGACTGGTTTTCAAAATGAGTTTCCTTTTTTGTACACGTAGAACTTTTTTTATTTTCCGATTTCTGGCGTTTAGTTGCAGAAATTTTTTTTCCGCAAAGTCAGGAAAAATTCAGAAAAATAGGACAGTCAAAAAATTGTAGCTACAATTTTTTGAGTGTCTTTTTCTGAATTTTTCCTACGATTTTGCGGAAAAAAAAACTTATTTTTTCATGAAATCGAGTACCCATCCAATTCCACAAACTTACTCGTTCTCCTCCATACATTTCGTTTGTTCTCCAAACAAGTGGAAAACACATATGATGTTTTCTCATATTATCATTCCAGTACAGCCGGTGTATCGACCGAAGCTCCGTGCCACAGATTCTGCACGTATTCCATCGATTGGATCAGCTTCAATCGCTTTCTCCACAATGGCCTGAGGTTGAGAAGGGAGTCGTCTGGAGAAAAATAGAATAGAATCATGATTTTTAGGTTATTTTACGTTTAAAAATCTAATTTTTAAGACGCGTAAACGTTGGGCTCATTTATAAAAAATCGGCACACCGGCAACTTTGCCGAAATTTCGGAAAATTGTCGGTTTGCACATTTTTGCGGATCGTGAAAGTTCAGAACTTCGATTTCAATCCGCAAAATTGTATACATCCTATCAAAACATCAATCTTGAAAGGCCATTAAATACTCTCTATGGTCTAAAGAAAAGAAAACGATGGTGTAAAAAGATGCAGTTTTAAATGTTGTCTTATTAATAACAAAATTCGACAATTTGCCGGAATTGCAATTTTTTTTTCTCCAACTTCCGAAAAAAACCCACCGACCACCATAATATCATCGTCTTCTTCTGTTTCTTTTCCAATTCCAAGCCCTTTGATCGCTTTTCCGGTGGCTGGCTGCATGAGCTCAAGGTATCCGTATACATAGATTTTCATGTCTGAAAGAAAATTCAAATTTCTTCTGGAATGTTACTCGAAAGTATCATTCCGGACATTACTCGTTGCCGTCGTTTGGTCAGTGCACGGAGGCTTGCCGGACGTGGAACACGCATCAAACGTAAATAAAGGATACACGGTTCACATCCGTGACGCGACATTACACATTTAGCTTAAAATTGTGAAATTAATTTTTTTTAATAGCATCTTTTTTTTTAAATTTCGCCCATGCTTTTTCCATTTTTTCAACGAGTTTCCTTATTTTTTGTCCATTTACTGTAAGTTTTTGAGAATTGTTTTTTGTTAATTTAACATTAGCAAACATTTATTAGCAAAAATTTTATTAGCAAAAAAACTTTTTTAATTTTTTTAAATTAGCTCAAAATTCTCGAAATTTTAGATTTTTAAAGGGTAAACAATATAAAACTTAGGGAGTTTTGAGCTATAAAACGATAAATTGATTTGAAAAAGGATGATAAACTTAGTTTAAAAAACCGACAAAAATAGACTAAAATGAAGGGAACACGGCAGCAGCTTAGCCCCATGCTTAGCCAGCAGCCCTGTAGCAACCCAGTATCAATAATATCCCGTGCCAATTTTCTAGAACTGAATATAAATTGGGTTGCAATGTTGCTAAAGGGCTGCGAAAGACTGAACTGGGATGAACCTGGGCTGCAAGGGGCTGCGAAGTGCTGCGAGGGCAAAGCTCAGGCTACAGTGCTAAAAGGGGGCTGAGCCCAGACACTCAGGAAAAAACTCCATACTCGCAGCCGCACCACATTTGCGCTCTGATCGCGTGCTATCCGCGCGCACAGAAATTCGAAAGTATTACTGTTCCAAATTCGGAATGCGCGCACGAGGGAGAAGACGCAATTAGAGCGCGGATCTGCACGTAAGGAAGAAGTGGGACTGGAGCACGAACCAGTAATCTAGTCGCGCCTCCGCTCTCCAGGAGGTCTAGAGCGATTTGCCGAGCAGGTCAGCCCTTCGCAGCCCTTCAGGAAGTACAATCAAAATTATACAGAAATTTTATATTGGAACGGGATATCATTGATACGCCTAAACAGCCCTATTAAATAGTGATGACGGCGTAAATGAAATTCGCCATTTCCAGCTAACATATAAATTTTTTTTTTTTAACATTGATATGAATGGATTCAGCAGAAAATTTGCCGAAGTCATTGGAAAATATTAAGATTTCCAGATTTCGGTACTCCACTTTTAAAACTGAATTTTAAAACTGTAGTCTTTATTCAATGTTTCTTTCAAAATTTAAAAAGTAGAATATGTGAGAAAAATTTCCAAAATTGTCAAAATCTCTAATAGCTGAAATATTTCACGGCCAACCGGCGGGGGGTACATGAGAATTCTCTACCGTATGATTCCAATTTGGCTGACTGCGTGCTCAACGTTGACTAATACTGAGTGTAAACTTTTCGTACACCGTTGCGTACTGCACAGCGCGCATTTTAATTGACGACATTTAGCAAAAATTATAAGATTTTTCGGAATTATGAAGCGCAATTTTCACAAAAATAATGAGTTATTTGTAGAATTTATGAAAAATCGTGAAGATTTTTTTCTTGATATTCAAGAACAAGCAATTTTTTTCTTAACAGAGGAATCCTCTCGCATGCACCTGTTGTTTTTTGCTCCACTTTAGGACGATAAAAATGCGAATTGTTGATAAAATGAATGATAAATAATATAGAGTAAAAGTGCAAATATGACTTCAGCAAGTTTTAAACCCAAATTTTTCCTGGTCGATTTTCTGTTAGATTCCTGGTTTTGAGTAAACAGTCTGATATATTCCTGATTATAATGATAACAATCACGAACATAAGAATTGTAGAGCACAGAGAAACAACAAATTGCAAACACAGCAACTGATATCAGAATTAACGACGGAAGTACCACGGAAACCTCCTCGGTCTCCACCTCGCCCACCACGGAAGCCACCACCTCTGTCGCGTCCTCTGAATCCTCCTCGATCTCCACCGAATCCACCTCTCCTCCATCGCGGTCTTCTGATATACCACGGAAGCCTCCACCTCCACCAGGATCTGTTGAGAGTCCTCTGAAGCCTCCTCGATCGCCACCTAAAACCACGGAAGCCACCACGATCCGCGGATTTTCCTCTATAGCCTTCGAGGCTTCAGTTGTACCCCATTCTTGGCACGCCTCAGATCTCTACAAAAAAAACAAATTAGAAGCATTTCAGACCATGCTTATCGAAATGTGTACCTATCCCGCTTTATCGCAATCTGTCTATACGTCTTATCCTTTTGGTTCTCAACTTCTTTAACTTGTCCAGTAGCGAGCTTGCTAACGAGCAGCATTTTCCCGAATCGCCTTCACCTCAGCCTCCACAGCATCCAGTGGCTCCTTGACAATCGTAACTTCGAGTAATACGTTGCTCACTCTCCTGCTCACGACGCTATTTCATCTGCTTCTTTTTATTGTCACCGCATTATGGTTGTGATAGAGATTAACCTCTCCGTCTCATCGATTTGTCCACTTCTTCATTTTTGACTCCGAGTTCCAGCGTCAGTCGGGTCCGATCTCACGAAGACGGACCGTAGCTATTCTGGCGAATTCCGCAGTCACGTCCTTCAAAAATGTCTTGTGGATGTTCTTCTTGCTGAGGGGGCTGCTGAAACCAATGTCGGCATGATGAGAGTTCCGGTATTCTGAATCCTTTTCCTGCGTGGGCTAGCGACGAGCTGCACGTCTGAAAATCAACGTTTTTGGAATTTTTGGGCGCATGATCTGGAGCTACAGAATCATTCGATTCTTAGAATCAGCATGCTTTTATTCATATTTTAGGATCTTTTTAAAAAATCTGGACCAAAAGTTTTCGAAAAAATTTTAATTTTTGTGACTATCAGAAATTTGAATATTCACTAAATCGAAAAAAATCATTGCAAAATCCATTCGTCAGCTGAGAACATTCAAAACTTATCAATTTGAAATCAGCATATTTCAGTGTATAATTAAAAAAGTTTCAAAAATTCTGAGACTTTTATTTTTGAGAAAAATAATTATTCGCTCGAATTATTGAATTTTCACTAAGCAACAGTAAACTTGCGCCCATGCTACAAGCCTGAATCTTTCAAATTAAGAACCAGCATGATTTTTTCAATATTCTAGGACGTTTAAAAAAAATCTGGACGAAGTTTTTGAGGAACGTAATTTATACAAAAATGTTCTGATTTTTCACTAAACTCAATTTATAAAAATAGTCAACGTTGCCCATGCTGTACACCTAAATCATTATGCGGAAATTCAGAACCGCCATGTATTTTTTCTTACCAAAGGCTCTTTAAAAAAAATGTGGACCAAGAGTTTTGATATTTAGAAAAATAACTCACTTTTCGACGTTTTTCGCCTTCTCGTTGCTAACCCGACAGTTGATTTTTGCGGCGATTTGTGGCGCTGAAAATTTTTAGTTTTATTAACGAAGAAAACAAGAAAAAACGACGAGAAAACATCAGAAAAATGCGAAAAAACATCGAAAAACCACCGCAACCTCGTGCTAATAACAAAAAAAAAGCATTGCAGCCGCGGGACTAGTTTTCGCAACTGTCTAGGCCATGTCCCGTTCGCCGTGCCGTGTATTTGTTTAATTCCCTTTTTGGAAAAAGTCAACATATTTCTCTAACAAATCGTTTTTCTATTAATTTTTGTCTAAAATTCACAATCAACAGATCTTTTGCATTGCAATTCTCACAATATCCCGACAGGAAACCTCAGTTACAAATCTGATTCACCTCTTTGAATAGTTCATTATTAGTGACGGTTTCATTCAAAGCACATTAATCATTGTTTTAAACTTTTGCACTTCGTGTTTTATGTAATAGAATTGTAATGGACAAAAGAAAGCAAGAGCGTTGGGGCATCTGCAAAAAATCATGAAATTTATTCTCTTTTTATGATTAAATTAGAATTTTCTAAAATTCCCTTTTTTTGACATATGCACTTACAGCCGCATGAATCTTGTTGAACCGTTTTCCGAAATGAAAGAAAGTGGACAAAAGACCAATGTTGATTCTTCTCCAATCATCATGAATTTCTTTTCTTCTCATCGCTTGAACCATCGCAGCGTCGAAATTACTTGACTGTCTCGTTGTTCAGAATGAACAGACCTGTAAAATCAGTTACTTTTTTTTAGCAATTTAAACAAAGTACTATTTCCAAAAAATAGGGAAAAAAAGGTTTGATTTTATAAACTCTCGAATTTTTATTATGGTCAATTGTTATTTTTTCCAGAGAAAAACTCATTCTCCCAATATTCAGAAGTTTCTCTCTAAATTTTTTTCCCATCGTACCCTTATCTATAGGTAATTGATATGACGTACGATCCAGTCTGAGATGTCTTCTGTAAGCCGTTTCTCGTTCATTTCGTCTGGAACCGCCCAATCAAGTTGATCTCTGTACGGTTCTTTTTCCAATTGCTTGCAGTTGGCTGTATAATCGCCTGATAGCGTGTTCGGTTCCCACGTGGATTAGATTGTCGACATTGAAAGTGGATTTGCTGGAGGAAATTGGGAATTTTTCAAGGTTTTAAGTGGATTTTCAAGCTATTTATAAAAGCAGGAAAAAGCTCAGAAATAAACTTTTTTTACGTCGTGTTTTTTCCAATGGAATTACCTACTTTTAACTAATTGTTCGGTTTAAACCCAGAAACTTGTTTCATATGGATTTTCCCGGTGAAAATAGAAGGAATCGTCGCATTCTCAAAGTTTTTTCACCGATTTGTTTCAATTTTAGCACAACTCAATGAATCACAAAAATTCCATTAGAGCCGATTTTCGTAAATTGGTTCCTACATTTCGAACGAAAAATTGTCCTTTCTGTTTAAACCGGAAATTCTCTTTTGAAAAACCAATGAAAATTTGAATTTTCTGCGCTTTTCTTCGGAAAATTATTCTCGAAGTTTATCAATCGATCCTTGGTCTTTTTTTGTTCCGCAGATAACGGCTGGCGGAGTTTACAAGCGTACCAAGTGGTTCAACTTTTATGCGATAAAGCTTTATAAATGGGACATAGATGAATAATATTTCGAGAGGCTAAATGCAAAAAGAATGAGTAAAAAAGCGCGCAGCCCCGTCCATCTCTGACGAAAAACGCCGTTTAAGGATCGGCTGGATTGCAATTTCCGAATGGGAGTAGTTCGAAGTGTCAAAATGCCGGAGAGGTAGTCGTCAAATTTCACCGAAACGTAACCCGGTAATTTCCACAATTAATGGTCGATTTTTCGCAACAAGTGGTATGTTTGTCAGGATTTATATTGTGGCAGTCCAGATTTTAAGGATTATTTTTGGGCAAAAATGTCGAAGTAATTTTCTCTGAAAAAGTTCGTTTATTATAATTCAGATTTTTTAGATAGTTTTCATCAATTTTGCCAGTTTTCAGCCTGAGAACCTTACTAAAGTACGATGTGTATCATGAGCGCCCCTTTCATGAAGCTAACGAGCTTCAGCTTCATCTTCGTCCTCTTCATCCTCCAAATCTTCATCCTCATCGCCCATTGATTCCCCAGACGTTGTTTCGCGTTTGCTCATGGATCTTATAGGACGAGCCTGAAGATTCAATTCTTTTAAATTCAAATTTACCGCTTAAAAATCGATAATTCTCCCGTACTCTGGTTTCTTCTTCTTGTTCCGCCTGCTCCTCTGGATCATCTTCCTCCATTGACTAGGGCCGGCATTCAACATATTCAAGCCTTCGTCTGAATTTCTGGCCAATTTATACAAAAACCGACAAAATAATAAGCATCACTTTCTTTTCGCGTCTTCGTCAGAGACGTGTGAATCCATTTCCTGGAATTTGAGTTTGAATGTTTTTAAACAAATTTTATGGAGAAAACATTCGAAACACTAGAACTTCTGTTGAAACACGAGAAAATTTTTTGAAAATCCATGAGAAAAACAGTTTTGAAAAATCTGTTTTTGGAGGCTCTCCGTTGAGGAATCGTCACCCGAGACGCAGATTCTCCGGTTTTTTCATAGTTTGAGTTTAAGAACAAAACAGTTTAAAAAAATGTTTTTAGTATTTGAATGTAACTTATAATGTATGTTTTACTTCCATTAAAAATTAAAAAAAACTACAACCCTAAATTATCATGTAAATTTGAAACCGTGAATCAATCTCCGCGGAAGGGCGAGCCTATATTCCGCAAGCGCACTCTATCGCTAATGTACAATGGGCGGTTTTTCTAACTGCTAGGAATTAATCGGATTCTCGAAGTTGATTTTGGGTTTCTTTTTTTCGGGAACATATTGGTGTTTTTGCGTTCAATATTCAAACTTAGAGGAAAACTGCTTCAAATAATTAGGGAAACTCTTGAAACGAAAGCGCTGAAAACAGGCAAAAATAATTATTTTTGTATTTTTTAGGCTACTTTCTATACTTTTGCGTACATACTATAGTTATTCTATAACAGCCATTAAAATTATTAAAATGATTTTTCCATTAAAAATAAAATGAGCAAAATGATTCTTTTCCAGAATCCTATATGCGCCTTTAAAATCTCTCGGATTACTGTTTCAAAGAAATTCTCCTTTATATTTTTAATTTTAAATTTTTTCCTGAATGTCAAATATTAGGGTAAAAATCATAATAATATGTGCTATTCATATGAGTGTGGGCAAGAATTAGTGAAAAAGAACAAAAACACGTATGGACTGTAAAATTGGAATTTTGAAAATAAAAATAATATGCAGAAACAATTAAAATTTCCAGGAAAAAAGTCAGTAAAACCATCAAGAAAAAACTACTCGATTTTGAAGGAAATCAGCAAGAAATATCGTAGAAAAAAGTATGTTTAATTTGGAAAACCCCTGCTTGAATTTGTTTACAGTAAATTGGGCATAAAAGCGTATTGGCAAATTCGCAAAAACAAAAATCTGGGGATCGTGATGTGATGGAGTTGGGTTTTGTGAAAAAATTCAGCGCGGAAAAAATTGAGTAGACTATTTCAAAAATGTCGATTTTTGAAATTTGTGAAAAATTGAACAAAAACTGTTTTTTTTTGGAATTTCAAGAAGTTTTATAAATTTTTTTGGTTAAGATCAATTTTGAATATTATCTAGTTTGGTTTCACTTAACCATGCAGAACAATTCGTACAAAGGTATTCTAGAAAGGAAATGTGCGCTCCAGCACATTATTTGCTCGTGGAGCGCACTTGTGTGCACGTACGCTAGACCAGAATGTGTGGTAGAAAGGGAGGGAATAGGAAAAACAACAAATTGGGCAATGTAAGATTCGGAGAAAGAATTGGAACGAAACAATATGTATTTCGAGCTCCGCGAGCTGGTGGATCAATCCACAGGCTCTCCATCCTTGCGTTTTCGAGAGGCACATTGCATTCTAGTTACACACACCCGAGCACGTGTATAATGGAACATTGAAGCCTGGAAACGAGCCATCGCTACCATCATTACCACGTGGATGAAAAACTTAAATTTTGATGATTCGAAAATTTTCTGGAAAAGTTATGATTGTGAGATAAATTGAATTCTTTGAAAAATCAAAATTGCAAATGCTTGTAGAAAATTTTATATATTTTTTTAAGCGTATCTTTTCTGTATACATTTCCAAATTTTTTTGTTACCCAATTTTAAAGATTTTATTGAATTTTAAAATTCCTTTCAGTAATTCGGAAACTTTTTTTCAACTTTTTGATTTTCCGCATTTTTTAAAATTTTATTCAAGGAGAATTATTAGATTCTTTTGAATTTAACGAATTCTGTTCGCTAAAAAATTTTTCGATTTTTCCTGATTTAACGTCTGACAAATATATCTGGTTTTTTTATTTTCCTGATTTTTCTGTTCGATTAAAAATTTATAAAAACAAGTTTTTTTCTAATTTTTGGTTTTGATGATTGTGTATTTTTTCTGAACTTTACAGTTTACGATGACACCGATCTTCCACATTAAAAAATTCGATACAAAAAAGCATTAACATGATTTTTAAAATTTGAATTATTTTTCAAAAAAAATAATATTTCAACTGTGTTTTCGGAATTTTCGATTTTTTCTGAGTTTTTTTTGGAATTTTTCCTCCTTTCTGCTACCAGAAAAATATTGCCAAATTCAATGTTGTGTAGTAATTGTATTCAAAAAAAGTGTTCAACTTCTGAGTCTAAACCTTTTCCGAATCCTTAAATCCTTGCAGAGCTCTCGTGAATTCAGTTGTCAATTATGTGAATAGCAAGCTGCGTAACATTTTAATGAAAGTTTTAGTTTGTCAAGGACTCGATTAATTTCCGAATAATCATAATCATCGACTCGAAGATCATATAATCCTTGAGTATAGTTCCAAATTACTTTGCTTCACGGAAAGCAGCAGTGTCAATTTCATTTTGATTCACGGCGGCTGGTGGTTCTCCTTCTCCAGATGCATGGGATGAGCCGGATGGCCTGAAAAATTAATTTTTTGGAATTATTATATTTTTCGGTTTATTTCATGCATCTCGATTATTTTAACAAAATTACCAAATTCAACTAGATTACAACTTGCACTGTGTCGATTTACGGGTTTTGGCGTTATACGAGTTGAATTTGTTTATCGATAGAATATTAAAATTTAGCTAAAATTGAGTAGACTATAAGAAGAATTTTTTTAACTTCAAAAATCATTCGAGGCAAAAACGTCACGAGCGTCAGGATCGACACAGTAGTCATTTATATAAAAACCAGTTTCGGCCACGAAATATCTCGCGCCATTCTTCAAACATCTTGGGTAGTACGTATTCTCAAAACTGTGAGTTCACGTATAATATTCATGCGAAATTTTGGTCTACTTTGTTAGAGAAATCATCACTAACATATTGCCAGTAGGCCGAATATGATATCGAACATTCGATCACGCCGTGACGTCATCTAAGTGTATCCGTATATTCATTCGTTATTATAAACATGATCCCATCCAACTTCTTCAACTCGGAAGGGCGGAATATCCTTTTCAGGTCTTCATTCTAAATTCAATATATCCAAAGTTGAATGGTGCGAGTAAATTGGATAATTTTACACGGCGCTTTTTCGCATAATATCTTCTCCATTTTTATCGATATTTGCATACATCATGATACAGGCGAGTAGTTTTTCCGTTTGGAACTATCTGTTGCTGCAGGAGCACTAATCATAAATGATTCAATAGTTTCAGTAGTCATTGCACACATCTTCGCTGGTGGCCTTGTCCTTTTTCCGACGTCTTTTCCAGCTCACTGATCAAATACTTCAGTTGGCCGACGATCTGGCATTCCTCATTTCGTTCATGATATAGGCCGACTGGCCTCCCAAGAGTCGGGTCGACATTATCGATATTAAGGAAATCAATCTGATCTTGTGTCAAATAACACGACGTTCGAATCCAATACAGCATATAACTGTGCACATTGCGTGAGTCGTTGAGATCTATTCCGACGGCGAGGTAGAGAGCAAACCGAGCAAGTTGTAACGATCGCCCAGGACGTCTGGCGTGCGGCGAGCGAAGAGCACCTGGAAATTTTCCTTGAGAAAAACCTATCATCGTTGTTATACGTTCCTTCACTTGGCATTGGAGTTGGCAGCATATGTTTTGAAAAAACGTTGTTTTTGTTGAAAGAACATTTTATATACGGGACCATGAGATAATATTCCTATTTCCTTACTGGCGCGAAACCAAAATATGCAGGCCACGGCAACGAGAGCGCATATGGCAAAGAGAGACGAATCTTATTTTCTTGTAATTTTTACGGTTTTAAAATAATTTAGAATCCTTTTCAACTATCTTGATTGTAAAATATTACAAATTACAGAATTTCGCTACCAAATTTACTGGAAATCTAAACTCTGAGAATGCGCATGGAGCAACATATTTGACGCGCAAAGCTCGTAGCGAAAACTACAGTTATTCTTTAAATGACCACTGTAGCGCTTGTGTCGATTTACGGGTTCGGTTTTTTAAAGAATTTTCGTGTTGTTCGAGAAGTGACAGTGGTATTCCTTTTCCTTCTTTCTTAATCCTATTATTTTATCATTATATGCTTAATTTTAATATTCAATTCATACAACTAAATTATTAATATTTCGAGTAGACATTCTAAGAATTCCGGTAGTATTCGCTTCGAGATATTTTTCGCGTGAAATATTGTTGTGAAATACGCATTCTTAGAATAGATGGTGCTCCCGTAATAATCAGATAAGAAAAGATTTAGTCCAAGAACTTTCCGAAGATTTCAATATTTGCAAAATCAGAAACCTGACCCCCGAAGATTCTTTAAATTTTAGAAATTTTTCAAGGTTTGCTAAATAACTCTAACTTATTTCTTCTATTAATAGGCCTGCAATACTTTTTCGATGGTCTTGCCGCTTCGGGCAATAACTATTAGGGAGTGCAAGTCTAATAGAGAGTGCCATACTATTCTTCAGAAAGTTTTTCCGTGTTGGGGCTAGATTCTATTTGAAAAAACTCCAATTTTATTTGGAAGTATAGAAAATTTGATTGAAATTGCAACAAAAAGCACAATAACGACTTCCAGCTCGAAAAATTTTGTTATAAACTGTTGCATAACAGGGAAAAAATGTTATTAAAAATGTTTTATTAGTAAGAAGTGTTACAAAAAAAAGTAGGTGCAAGACTATTAGGGAGTGCAACACTAATAGGTGCACTACTAATTTTCGGAAGGTCTCCGGGCAATACTAATACAGGGAGTGCAAATCTAATAGGGAGGCCATATTAATAGAAGATATACGGTATATATAGCTTTGAAAAATCGGAAAATGCCTAATTTTGCTACTTTTTGAGGTTTGAAAATCTCTAAAAATTCAATAAATAAAATTTGGGTCAAATTACCGCTAGATTATTCCCATGAATCATCCATGGTCTATGACAATTCGAATCAAATAAACCAATTTTCGAAATTTCATGTATGACCAATCATTGCCCAACAACCACATTTCTTGTCCACCCCAAGCTTTGCCAGAAATTTGCGACGATGATGATCCATAAGTGATAGGCATCTCTGACGTGATGCAGCCATTAGTGCAATTGGTAAGACGAGCCGAAGCTGGTAGATCACTTATATCAACGAACATATGGCCATAACTTCCTGTCAAATTATGAACATGTAGAGTTGGGAGTTTACATGTCCAGCTGGAATAATATGGAAACGTGAGGGAACAATTAGTTCGAGACGGGGAGGGGCAGGTTGGCTTAGGGTGCCAACCGACATAGCCGAACATTGGGGTTTCTGATCAGCTTAGCGCCAGCCGACCGTCTACTAGTACTGCAGCTAAATTTTCGTCGGCTGTCGGCTGGTGAAAATTTTCATAATCAATTTTAATGGATGTTCCAAATTTTTCCCTAACTTGACCAAATTTGTTTGCTGGCCCAGCGACACCCGATAATTTAGATCATTGCGCATTACGGCAGAGGCTACTTGGCAGAAACTTTATAATTTTAAATTCAGAAATTCAATTCGTTTTCAAATAATATTTTTTATAACTTTACCGATCAATCACTTCAATCGGATCAAATTTGAGCCAATACATCGCTTGCACTTTTTAGTTGTAGTGTGCATGTGTAGATCTTTTTATCTGCGAAGTGAGTCAATGAAGAATATTCGCGACCAGTTTCTAAAACTCAGTTTTCTAAGGAAATTTCTGAAAAGAAATTCGAGAAAAAACTGAGTCAGCAAAAGAAAATGGGAAATGTATGTCTGGAAATGTATTCGAATATTATATTCAAAACAGTTTTCAAAAAAACAACGATAGCAATGGTGATCAGAAAGGAAGGAACTGGGCGAAAAAAATTATCTTTGAATCTCTTTGCATCTTTGTGATCTAAAAGATAAAGGTTTCACATTGGAGATTTGTGAATGTGATAAGGGTGAAAAATGGAGATTAATTGTGGTAAGTAAATTCAGGAAAAACCTAATTTTTGGTGAGAAAATTGTGGAAAAACTATAAAAGAATCTTTGGGGTTTAAAACTCAAGTTTTTCGCTGTTTCCGCACTGTGCTGACCAGTTTTTTGAGAGTTTGGCCGAATTCGGTGATTAGATCAAAAAAATAATTTCAAAACTTTGCGCCTCAAGTGTGACGTATTCGTACTCTATTGCCGTTCCACCAAAATTTCCTTCATTGTTTTGTCATTTTTCTGCATAATAACTGATCTGGGTTTTTTTGCTGCATCACCCAAGTGTACGAATTTCCCTAAAAATTATACCGGTATTTTTTCAAAATTTTTAGTCGCTAGAATCTTTTTTATTTTCTTTAAAAAAAGAGTTTTCTCGCGAGTAGAAGGAGAAAAAATGTGTGGCCATACTTCTTCGTTAAAGAATGCACGACTAGCTATAGCTCAAGCCCCCTCTGGAACGTTCCATCTTCCTCCCATTTTCCCACGTTCGAGAATCACTTCTTTCCCTCAGCTTCTCTTCTTCTAAAACCACAACTAGACAAATGTGCTTGTTTTCCATTTTTCACATCGCCGAGAAACCCGCTATCACAGACTCAATGCGCCTTCACCGGAGACGGGGCTATTTGTGTGTGTACATTGTACTGATCTCTGCGTGATATACGAACACCGGCCTCGGATTGAACCAGAGGGGGGGGGGGAGGGGGGGGGGTGTGGTAAAAAAAGAGAAATACTCTGAAATTCAATCTAGAAGTAGAAAGAAAACAAAGCGAAAAATTGGACATTCGTCCGGCTAAAAAATCTCATGGAAAACAAAATCTACTCCGTTCGATTTGTGAGCATTTTCATCCTATCTCTCTCACAAACCCGACTAAGGAAACGATAAAGCCTGGGCCCATCCCCAAAGTGTGCTCTCATGCTCTGGAGCGTTCTAGACTGTCTGTAGAGCCACAACTGGCGGAATAGCACTGAAGTGATGGAGAGCCGTAGAGAGAAGAAAAAAACGATTTGGTGGCGGAGGAGATGGCTTCGGCCCTCCAAATAAACAACAATTACTCGATATCGTTTCCTCTGTGATGGTGTTCTCTTCAATGTTTACTGTACGATATTGAACAGGAAATTAAATTGAGGTACACTCTGAATACATATACACAATAAATAAATACAAAAACTATAGTTTCCGCACAAAAAATTCAAAAAAAAAACGATTTTTTTTGTCCGAGAGGAGTATATGGCCTAGAAAAATAAAACTCGCCGATGCCTCTTTGGTCTGATGAAACTTTAAAAAATTATGGCCGAATTTTAGATTTCTCAGGCCAATATTGATACGTTTGTCGATAAGTACCATAAATTAGTCGGTTTTTCACGGGATTCTTCATTCCTCATGCTCATATTTTTCCTCCATTGGCAATCTCCTGCTGGACAACGCGTGGGAAATCGTGTGCCCTACACGGGCAAATACATTTTGTTTTACAAAGCAAACCGTGCCGCGACGCGACACGCAACGAGCCGTAAATCTACCCCAGATATGGCCGAGCTATGCCCTAACCTGTCAAAATCTTCCACTTCAAAAGATGAGGGAAGCCATAGAAGCTCCGCGTGTTGTTTCTGAAAAAAAAACCCGCCTAAAGTTGATTTAAATTATCGTTTCTTTGGAAATAATAAAATCGATGAATTTGTCGATATTGATAAATTTCCGATAAAAAAAAAATTACTTAAAAGAGGAAAAAAAATTCTCTTTTAGTACCAACAAATACGCCCATTGGACTAACCAAATCGTTCTTTCAATCTTTGTTTAAATCTTTGTGCGTCTATAATTGTCGCTTCGGAAAACTACACAAAATCACACACACACACAAGGAGAAGAAAAGAAAAAACGTGTTCCATGACCTGCCATCTGGGCTGATCGATCTGTGAATTGGGGAAAATTGAGGTATACTGGTTTTTTATCGGGAAGATTTTTTCGGAAGGATTGAGATGAAAGTTCGAAAGGTAATTCGCAAAGTTGAGATTTGAAAAATTCGAAAAAAAGACAATCTCAATTCTGCTGTAACCCCCAATTTTGCGTCATGGCCCAGAGTATGCAGCGTGCCCTAGAAATTACTAACGTGGCCTACAAAGATCACGGCGGTATCTATGATTTTCTATGTGCGTGACCTAGAATATACAAGACCTAGATTGATTGCGTAGAACATCTCCCAGTATATCCTAGCAGTCTTAAGTGGCAGTTTCTCAGTTAGTACGCCCAAGAATTCTCACGTCAGCATGACCTAGGATGTTAAAGCGTGGCCTACGAATTTTCAGTGTCTTCTAGGATATTCCAGTCTAAAAATTGGTTCAGTGAGGCCTGAAATCATCGCGTGTCCTAGAATGTTTAATTGCAAAAAAAAGATTTGAAAACTAGTATTTCCCTAGAATTCAGTCTGAGCATTATTTTTAATCTAGTTTTAAGGAAAAAATCAAAATAATAAACATTTTTTGATTAATGTCTCCGATCTACAGATGGGTGCAAGAAAGAATGCAACATTGTGATTGCTCGGTGGAGCATGACGATAAAAGAAAGAGACAGGTCCCTCACCTCCCCAGTGGTCGAAACAATTATAAATTGGACAAACGGAGAAGGGGTCGGGCAGACACAAGAGAGAGAGTACGTGAAGAGGGTGTCCAGGAAAAATGGGATGAGGGCAAATCTAGTTCAAAGATGAGCACTTTTCAGGATCTTTGATTCTGAGAAAATCAGATTTTGAACAAAAAGAATAGTTCATAATTTAATGGCATACATAGAAATATTTTCAGATTGTTCTTCAAAGAAAAATATTTTTATGGGACATCAAAGTTTATTTATTGCATTCTTCCAAAACAGTGGCCGGTCTGGACAGTTCGAATTTTTGTTAAATGCGAGGAGGTGTGCGCCTTTAAAGAGTACTGTAATCATTTCCAACTTTCGTTTTAATATTTACTTGTGGGAAAACATTAATGCTTAACGAAAAATGACAGTACTCTTTAAAAGAGCACATCTTCTCGCTTGTGACAAGCATTTTCGCGTCTCGGTGACAACTTTTAAGTTAAAGGCACAATGATAGAACTTTTCTGAAGAATTTAATTTATTTTTAAGTTAATTGCTACTGGGCTGTATCCTTTTTCAAGTCGCACGAGAGCCAAACTGTAGCAAATCTTAAGAAAAAAAGTCGACAAAACGTGCCGAAATTAGTAAACTTGAGAGCTTTAAAACTCTATTATCAGTTCTTCGCCAACAAAAAGAGTACCGTATCAGAAACGACCTTCGACTTTTTTGGCTCTCCTGCAACTACGGACATGAATTAGTTCTTATTGACAGTTTTCAAGTTTTTTTTTGGGAGTTTTATTTATTGTGCATTTAAAAAATCGTACTTTTAAGTTTGATGCGTGGCCTAGAATTTGCCCGTGTGAGCATCTCTCCACGGTAGCCAAGAAATTTTCTACCGTGGCCTAAAAACTGCCAGTGTAGAAATACTTTATTGTGGCCTAAATTTTCCAATGGTCCTGTTCTTTTTATAGTTCGAATGCACTTGACTTTTCGTTCGACCTGGAAGCGTAAAGAGTGGTGGCCTAGAAAACGATTCATGAGCAGAGTATTGAAAAAAAAACGAAATTTCGAGCAACAAGCGAACAAAAATCGTCTGTCGATAGAGTCTTTCGAATACTGGGGATGCAAATCAGCAATTCATTCTAAAAAAACTTTTGTGATAAGAAATCAAACTGATAAGCCAGTGTAAAGTCACGTAAAGAGGATTGAAAATAGCATTTCAGGTCGGGGTACGGTAGGGTTTTTGTAGAAATCTTAATGCAACATTTCAATGGGCAACGAGTTCGTGGCCTAGAAAAATCATGTCTGAAAAATTTGCAAATGCGCTCCGGTAGCCCGGATTGGTTAAAAATTTTCAATGCCTATTTGAAGTGGCGGCCTAGAATATACCAAATAATGGTCTAGTACTCAAATTGGCGGCATAGAAATCAACCTAATGAGCTAGAGAATCTTGTAGGCAGCTTTGATCACCTATGATAGGCGGAGGTGATAGGTAAAATTGTAGACAAAGGTAAGTTGAACATAGGCGTAGTCGTTTGCAGGCATACATAGGTCATTTATTAGGCAGATGAGGCCTGATTGTACAGTGCCGTCCAAAAATATATCCTATCTTTGACTTTCGATAAATTTACAAATTGCGTTTTCAAACGAGCACAACTTTAATACTAGAAATGTTATCGGAAAAAGTTCAACTCATGTATGTATTGCCCATCATTACGTCTACTCGTATTCAATTGTTTGTTGTTCAGGCTACCTACTGTCACGGTCCGACATCAAATACAGCGGCCGACATCTCGTAAGCCCGTTTTTGACAGCCCACGTTTACTGATTCGGCCGTATCTCGAAAACTTATTTTTTTCTGAAAATGTTAAAGTGAAATAGTTTTCATATTATTTGTTATCATTTGTGTTTATTCACTTTGTTCTGAAAAATCCAGTAAAAGTTATGGGAGTGCAAACTTGTCGCTCACTGCAGCTTAAACAATCAAAAATCAGGTTACTTAACTATAGTTAGTTCTAATTTTTTTTTTGTAGAGCATTTTTTAGAAATAACACATGTAAAATCACATTGAGCGAGCTATATTCAAACACGATGATTCAGGAAAAAATTCATTGGTGGCGAGAAATGTTCACGGCGTAACACTATTCAAGTTTGATCTCTCATAACTCTTTTTCTGGATTTTTCAGAACGAAATGAATAGACATAATGACAAGTAGAAAACTATTTTAACAACACCTCGAAAAAAAAATCGCTCCTCGACATACGGCCGAATCACTGAGTCGTTGTCAAAAACGGGCTCACGAGATGTCGGCCGCTGGATTATTTGTCGTGGCACTGGTAAAAAACTTAAAAAATTGAATACAAGTAGACGGAGTTATGGGCAATACTTCATCTGTTAGCGAACTTTTTTCACAGGATATTTCTAGTTTTAAAGTTGTGCTCGTTTGGAAAAGTTGTAGCAAGTTATCAAAAATCGAAGATGGCATATGTTTTGGCCGGTCCTGTAGGTTAAATAATCTCGTTATCAGGTGTAGCATGAATCAAAGCCATGTAGGCGGGCGTAGGTATCTTCTAGCCGAGTAGGCGTGTTACCTAAGGAGTCAAATGCAGACGTAAGTAATCATAAATAATTCACACTTTGTGCGCAGGCGTAGCTCACCTTGTTAGACAATCATAGTTAGCTTTTAAGTAGGGTTAGGACACCTATTATAGGCAGGTTTAATTCCTCTTATATGTGTGCGTAGAACACGATATAGTCAGGTGTAGGTCACTTTGTAGGCAACACGTCTAGGTTCTTCTTTCGGCAGGCGAAGGTCATCTTCTGAGCAAGGTTTGCCTTGTAGAAGGGTCGATGTACGTTGCCGTAGGCAGACTAAGTTACCTTCTGGGCCTGCCTATAGTGACTAGTAAGGCAGGTGTTCGAACCAAGGGTGTCAGTGACCCGTAAAAATTACAACAACGGGACAACTGGATGTCCCGTTCCCGTCAAAATTTTGAAAACGGGACAACACGTCCCGGTCCCACGAAAACACCCAAAAAACGGGACAACGGGACCCGTTCCCGTGAAAATGCGCTCAAAAACGGGACAAAAACGAGACGTCCCGTTCCCGTAAAAATGACAAAAACGGGACACCGGGACTTCCCCTTCCCGTGAGAATGTATTTTGAAAACAACGGGACGTCCCGTTCCCGTGAAAACACCCAAATACACCCAAAAAAACCGGACAACGGGACAAAGAGACGGGACACGGGAGACACCCTGGTTGGCACCGCACTGAAGAATGCTGAAACCAACTTTTTTTTCAAAAATGGCCCTGCTCAACGAGCCGAATGCATTTTGGTCGTATAATATTGGCATACCTTTTTGCCACCGTGAGAATCATTGAACAAAATCATGCACTTTCAATTTCATTTTTCATTTCATCAAATAAAAAGATTCGGGGATTTGATATATATTGGAAAGTAATAAATGAATGGGAGATTTGTATGGATCGAGGGGGAAAAGTGCACACCCCGGGAAATGATCAATTTGGAGCAGGCAATTGAAGGAGCTGGAGCAGGAGGCTACACTAACCACCCCTTCACAGCTAAACACATGGCTAATAAAATTGAATATTTGAAGTGAACTACTAGTGATAAGCGGTGAAACGGGGTATGTGGCCCTCATTTTTTTTTGACACTTCGAAAACCGCATTTCTTATCACTTGTGTGCAGAAGCATTGAAGCAGGAGGCAAGTGGTGGTCTAAAAATTAGAAAAGCTCGGCCACTGCTTGCCCGATAGGAGCACACGGTCGCATACTGTTTCAACAGAAATTCGAAAAAATTGGAAAATCCCGTTGATTCCGCTGAATCCGACGATTAAAGAAATTTATCCTCGCGTTTCTGATTGCACTGAAATCGCTCAGTATTCTAGAAATTTGTTTTCTGCGAGTGTATATTGTTTTGGAAATGTTGTGTTCATGTTTTACGAAGAACAATATAATATTATGTATATTAGTTATTATATATTATTATAATAGAAATTTTACAACGTAAAAACCCCAAACTTCTAGAAGAAATTGCCTCGCGTGTCTCATTACAATAAAATCAGTTTTTTTCCTTTATTTTATATTACAATATGTATATCGATTCAGCAAAACGGGCGGGACAGAAAATTAAGAAAATGGCGAATAGTTCGTTCCCGCGGAAGTAAATTTCCCCGAATTGGGGAGAAAAAATTCGAATTTTTACTGGATTTGTCTCAAGCTTTTGAATCTAGAAACAGTTTCTCTCTAGTAGAATCTCTTTAAAAAATTTTCGTTGCACCAAAAAGTCACTTTTCCTACTGAATGCGAATTAAAACATTCCGCCAGGAGACCACACAAAATCGAGAGACTTAGTTAGACAAGTAGTGGGAAAATAAGAGGCAACAAATCATCTCCGAAAGTTTTTTTGTGCAGAGTAGGGGAGAAGTTGCGGCGCTGAAAGACAGAGAAAGGGAGAGAGAGACAGAGAGGGTGAGAGATATAACAGAAAACCAGTATGGCGGAGGAAGAGAAGAAAAAAGTGTTAGAAATATTTGTCCGTCGACGCCTTCTTCGTCTTCGTCCTTCATAAATGAAACCATGAATTTTCCTCAGATATTGCCTTACTATTAAATGGGGCCCACGGGGGGCGAAAGGGTGTGGCCGGCCGATCCAAAACGGTGGCCTAGCAAAATATCGGCGGTGGCTCACGGTATCAAACAAAAAAACAAACATCGAATGACCATAATTTTTAAGCTTTTCAGTTTTTGGAGTCATTTCTGATTTTTATCCCAAAAATAGAGCTCTGTGCTATTTTTATGCAGAATCAGCTGGCTAAACTTGGTTTTCGGAATTTGTGCGAGTCTTAGAGATTCCCGACACAGCATCGAGTTTTACTGGAGAACACGTAGCGAGCACAGAAAAGGAAGGAAACAAGAATTGGCTCCGCGAGCAACCAAGCAGCCGTTCAAGAACAAACTGACCGAGCAAAGAACAGCGCGATAGGGCTCATGTATATCTTCTAAAAATAATGGATACTGGATAGAGAGATGAGAGACAGCAGCAGATGGTCAAATGACGACAAGCCACTTTCGAAGATTATTTGGTTTATTCATGCGTGTCTTTTTTTTTCTTGCAAGAAAAAATGATCATTAGCCGAAAATTAAATATTGGTTGTCCGAAGTACAGAAATGAAAATAAATCGTCCGCAAGGAGTACAAAATTCAAAATGGCTATTATCAAAGAGAAGGACACAATTCAAAAGTGTATATTGTCCGAGCAGGAGTACAAGATCCAAAAAATGAATTGTCCGAGAGGAGTAAAAATTCAAACCACAAAAATCCTGAGAATTTCAAGAAAGGGGCGGAGCCTGATTCGAGTGGACTGTCGTTGCAAAACGCAAAACTTCAAAAACATACCGTTTTCAAAATCTACCTCGCCGACCTACCGTAACCCTCTAAAATTTCTCTAGGATCAAATATCATCGCAAGAAGTGTTCGTTCGAAACGAAAAACGTATTTCTGACGCCTCATCACTCATCTTATCAGTAACAAACCTGAGAGAGACGGAAACAAAGTTCCGAACTATATTTTGAACCGAACAGGGATCCTGCAAATCACGTAATGGACAAAATGCATTGCTATGCAGCAAGACGCAATTGCATTCTTCAGCCAGAATATCGATTTTTACTACGTACGTATAGTGATAAAAAAAATAGATGCTGAGTTACGATCTTTAATTCGCCGGATGTGCGAGGTTTGCATTTTTTTTAGCCTTTCGAATTGTCGTGCAGAAAAACCCGTAAGCATGATTTTTCTCAGTAAAAATTTCTTGCGCCAAAATTGTCTTCTATTTTTTTCGCGAAAAATCAAAAATCTCCAAAACTTCGGTGGAGCGCACTTTCTGGACCACAATAAGCGAAACATCTCTTTCTGCGGTTTTCAAAAAATAAACGAACAAACATCAACAAGAAACGAGAGAGAGGTTTTGTTGCCTTAAAAAAATGGATATCGAATTTCTGTGCTCCATTTCCCTCTCCGAGAAATGGCGCGGGGAACGTGCAAACAGTGCGAGTATGTCTAATGGCTCTCACGTAGATCGAGAATCTCGAGTGGAAACTTTGCTAGTATAGACAGTTGAAGGAGGCCGGAGTCTTTTATTCTATTGGGGAACCGAGAAAATTTGTTTATGTCTGGCCGTGGAGCGTAGTTAATGTAATTTTTTTGCATTAAACGTGCTCCATCGAACAAGTAAAAAAATATGCATACTAGTATGTACCTTAAAATAGTTGTAACACGAATTGCCTGTGGAAATAAAAATCACGGCAAGTTCTCTCCATAGGATCAATGTAGGGAATTTTGCTGTTTATAATGCAAACGTCGAAGTCTCTAAAAAGCTACAATTTTCGATCGGTATCGTTCATGCATTTCGACTGATTTTCGTTATTTTTTATTGGAGTACGCTCGTTCTATCGAAACACGGGGCCCGAGAAAATATTATATCCAAAATCTAGAGAGGTTGTCTTGCGCTTAGCCGAAGTGAAGATTAAAATTGTTCAGCCTGCGTTGCCCGACGACTTTTTGTAAAACTTGGCCACCAACTTTTTTACGAGGCTGCGGCTACATCGCATTTGGGTGACTTTATATGTGTTCAGGGTGTCCAAACATGCACCCAAAAGAGAGTGTCATTTTTAACGCACGAAACAGCAATCTCAAACGGGGCGACAAAAAATGAGAGAGAGAGAAAGACGGGCGCAATCTAATGTTTTATCAGTGTTCTCTTCTTCTCCTCCGACCTCGTTTGCATCCCCCTAATTAATCATTCGTTGGTTTGTAATACAGAGAGAGGGAAATAGTGAGTGTGAGGGAAAATTGGAGATTGAGAGAGTTAGAAATAGAGAGTGAGAACTTCAAGTCACTTTTTAGCCGTTTTAAAAAGTTTTGGTCGATGATTTTGACATTTGATAAACCTGAATGAGAGATGATGCTTAGATAAATGAAAATTGAGATGATAATTATACATGACTTCACTTAGAGCGATGTTGTTTCACGTGCAAATTGGTGATTCGTCGAGAAGTTGTGACTGTTCGTGTCGGGAAAATTTCACTAGCTGTGAGCGCCCTTTTTAAAATGTAAAGTAGCATAATTTATTTTCAGAAAATTTAGCGTTGGAAAAATAAGTAGTGCGCAACATATTTGACTCCCAAAACGTTTTGTAGCGAAAACTACAGTAACTCTTTAAACAATACTGGTTTGGTTCTGGTGTCGCGGGCTGCCAAAATTCGAAAGTAAATTCATTAATAATCGAACCAGTAAATCGAGCGCTGCAGATGACAGTGGAGGAATTAATGTTGTTTTCGCTACTAGATATGCGTCAAACATGTTGCGCAGGACACATTCTCAGAATTTTGTGTTCCCGTGATATAACAATTCATTTTTCTGTCCCATATAACCTCTTTCAATTATAAGAAACCATTTGCAGCGAAACACAAACAATTTAGCCGATTTCTATTTCACCTATAAAATTCGCGTCAATGGCCCGCGCTGTCGAGATCATAAAACCATATGTTATGCAAATGGCGTAAAATTCAACGGTGGCCGCCCGCATGGTCATTGATCGTTATAAGCAGAATGGAGGAGGGTACGGGGAGCATCACTTTCCTGAAATGAGCCCGCGAGAGATTAGAGAATTAGAGAAATGAGAGATCAATGAGAGGGTGAAAGGTATGAAAATAAGAAAGGGATGTAAATGAACACGGATGGAAATAGATGGAATAATGAAGTGCGCAATCGATGCACCATCTCAGATTTTTCGGTTTTCGCGGCAGATAGTTGAGGAATTACATTTTTCGGGCTCCATCGATAATGCCCTGCCGGACAGCGCGTTATGTGAGTCTCCACAGGGGCAAATACCTTTAGTTTTACAATGCGAAACCCGAGCTGCGACAACGCGCCGTAAATCGCCCCCAGCCGTGACCGAAAATGGCCTAATTCGTCAAACTTTTACATTCCAAAATATCAGGGAAACCAGGTGCGCGTTTCCTGTTGTCCGAAAAAAGATTACAACAAAAGAGAAGAAATGGAGCATTTGCGCGCCATACACTTTGAGACAATTTCATTTTCCACATCCTATATATATTTTCGTTTTTCTGTCGTATTTTGTTGACTTTTAATTTATTGGTATTTCGACCGATTCAAAAATAATTATTTTGACTGTATTTTGCATACATGTAGAACTGGTGTTTTTTAAGATATTCGGCCCATTCAAGTTTTTCAGTGTATAATTGATATATGATTTCATTCCGAACTGAAAATTATATCGAAACGATGGAAAACCTCGGATATTAATACTGATTATAGTGGCAAGAAGAGAGGAATCGGAAAGTTCGTATGGATCAAGTTCACCGATTCTCGAAACACAGTCATCTGGCCGAAACTTGACGAAGTTACTGAGGATGAATATTCTAATTCGAGCAGTAATGAAACTAGCGACGAAGAGGAAAACCTCATACAAGAAGTACCAAAAGTCTTAGCTATAACAGAGAGGTAAGAATTGTGTCTTCTAGTGACTTTTCGCCAGATTCTCTAATATAATATATTTTGTTGTAGAGAGAAGAAAAGTTAACGGAAAACGAGACGAATTCGTTTTAACGGTAATCCTTGAAGTACAAACTAGCAATACTAAAAAATGCGTGAACGAGATCTTATTTTCAATATAATCATGGGCAAAACGATGAAATTATGAAAAGTCTCTTATTGGATACCGATGGAACTATGACTGCAGCAACAAGGCTTGTTCGGAATGTGCCTACGATTGGAATCAGTGCCAAGTTACTCTCTGGACTGGATTTATTAAAAATAATATGAGCTGCACGTGGCACTGCAAAAAACCGCTTCGCTTCAACAATGCTTCTTGTGGTTGGTTTGCTTTTCAAAAAATAGTTCACTGTTTCAGAGGTTCAACCAAGTCGCTTCTTCATGTTGAAAATGCGGTGCCCACCCGGACCATGTAATCGCTCTTCCGGAAACACATTGGCGACCGATTTTGTTGGTCCACCTCTAGTTCTGTGCGAGAACAGTGATACAACTAGTATTTTCAGGACAAAGGCTCGACTGACTGCGGAAGCTCCCGCATCTGAGGAGAATCTCAAATCAGGATTCCATTCCAAAGCGACAACTCGAACGCTTTCCAAAGATCGCATCAGAACGATCCACAACGTTCATCAGCCGAAGAACATGCGGAGCCAGATATCGTGGTGGATGGCTGAGTACGCAGCTCGAATGCCTTAAGGCGAAACAATTGGTTTTTTAATTAAGCTTGCTGGTCATGTTAATTTTGAACGTGTTAGTTCACATTGTTTTTTTTTTTAAATGTGTGTTGTTCTAATAAATTTGATTAATCACACGTTTTCTAGTCTACTACGTGCGTCACGAGATATCAGTGGTTTCTTCTTATCAGAAGCTGAATCATTTCCGGTTGTCAATGTTTGTAGGTCAAAAGAAAGGCTGTGTGATTTCGACCATTGATTTGTTTATATGGATAAGTTCCTGCCTTTTGGAAGGGCAGTATTCCCGGTATATATGGGCCTAATACGGAATCGAAAATAACCTGACACAAACCTGACGTTGCCTGTTGCCGGCGGCGGCTTAGTAACTTGACAGCGGGTCGCGATTTCACCTGCCTGTTCTCCATTCTGCAGCGAGCGACCTGCTGGCAGGTTGCCACTAAGCTGACGCGGTTTACCTGTGTTATGGCGCGTGCTCAGTCGTTTCAGGAAACTAGTAGCATCAGAAGATCGGGGTTCGGGAAACTGCCATCCGGGGCTTGAAGGTTCTATGAAACAGGGCGAATGACAAGGAGAGGCAATAAACAAGTAGTAGGCGTCCTCTAGAAAACATTTTTGTCTTTAATACGCGTTTCCTACTGATGCCTTATTTATTGATATTTGGATCCCCTTTTCTAGAATAAAAAATCAGAATCAGCAGAAAAATTTGAGAAAAAGTCATCGCCACTCAGAGTTGGTCGGAGTAAATCAGAGATAGGCATAGTAAATCATAGCTAGTCAGAGAATATCAGAGTTAATCCGGGTAATAAGTAACCTAGTCATAGCATATCAGAGCTAGGCATAGTCAAGCGTGGTTACTCCCAGTAAAACCACACTTGCACCGAACTGCGGCTAGTGTGCTTTACCTGTAACTCCGCTTTTTACTCTGAGTTAGTATGATATGATTTGTCTGAGCTGTGGTTGGGCTTCGCGGAACTTGAATAATTCGAGACAAAATCTAAAAATTTTAGCGAATTTTGTTTAATTTATTTGAGGTTCTACGACAGAACTCGAAAAATTTCGGGTTTTAATGTTTACACATTTTATAAATTTAAAATTGAATACTCAACTGTGGGACTCCTCGAAAATCACATGCTCATTTAAATTTTGAAGTTCGAACCTCAAAAAACGCGCAAAAACCAAATTCAGCTAGGATATCAAATTTATGATTGAACCCACATCTATATTTTGATGCGGTTTATAGTTTCTGAAGTTTTCGCGATAAAATCCGAATAATAATTACCCGTACCGTATATTCTCAATCTAATTCCCAGGTCATTTTTTCATGCAGCACTATGAGAGACTGTCGTTACTACTGGACAAAAGAGCATTAATTTTCGAACGGCTACTTTTAATTAAAGATCACTAGTATTTAGTCACAAAAGCTATTTTTTAAGCAGAAATTCATAAAAATGTTTTCAATAGCGAACTTTTGTAACCAAAAGACCCAGTAAAACGATTCAATTACTTTCGTCAATTATCAAAAAATCATCAAAAATATACAAAAAAATACCAAAAAATATTGAAACTTTCAAGTGACTCTTTCAATAGAAAATGGGGAGCACTAATACTGCTGATTTTTCGGACCCTTTTTGAATGCAGCACTATTAGAGACTGCAGGATTTACTACTGGAGTGATGCTGCACTAATAGAGAATATACGGTATATAATATATTCTTGCAGAAAAAAGTACGATTATCAATGAAAATTAGCTGATAAGAGGCTTTTGTTTGAACTAAGACGACGGAACGCCTCTAGTTCAAAAAATTCTAAAACCACGTTGTGTCAGGCATGTCTCATTGCGGTTTGATCTACGAAAAATGCGGGAATATTTTTCCAGAAGAATTGACGTCAGCACGCTCTTAACCATGCGAACCGCAGATGAGATGTCTGCGTCTCTTTTCCCGCATTTTAAGTTCAAAAGGGACTTTCTGACACCACGTGTAAAAAGGGGTTACGACGGACCCTGGCCTAGAATTAGGCGTGAAAATGCTCTGGCACTGATGTAGTGAACCGCGATGCAAAATTGGGGGCCGAAAATTAGGCTTTCCTTGCGAGAACGATTACTTAAAAATGTTTTCCTTTGTCGAAAATTTAAAAAACACACCACATGTATTCATCTCGACCAACGCCTCGTAAATGTTTTCAAAAAAGGCGGGTAAAATTAGTTGAATTCGCCAAGAGGAAATTCACCGCTGTTGAGCGCGTGCAAAAATTTCAGCACTTGCTGACGGTGTTTCCACAAATTACACCGATTAGTGGGGCAGAAAACACGTGCACACTCTTTCAATAAAACTAGAAAATAAATCCCAGGCCTGCATATATTGCACAAACCGTAATCCCCTTCGCGCTAAACAACACGCGCAACGATGCTCCGCTTGGGAAGGAAAAATTAATTTAACTCGGGCTTTTCATTAAACAATTTTTACATCGTTAATTTTTCGATGTTTTCACTGCGAAAAAGTGTTAAAATAACGATTTTTAAACCTATCTTCAATGAATCCGTGCAAAAAATCGCGATTTCTCGAGTTTTGAAAGAAATTTATGAAACAATCGGCATTTTTAATAATGGTTTGAAATAAAAATCTAAATTTTTTTTCGGTGCAGAAAAGTCGTTGCTCGCACAGTTTTTTTAAAGCATTTTCACATCAAACTCCGCCTTTTTTCCAGTAAATCGATCTAATATGTAGGGAGTGCGAGACAAAGCTGAGCGACGGCGCAAGCGGCTGGCTTCGCCGAGTATCCCGACAGATATCGATCCAAAAGACAGACTACTCGCCATATATCTTCCAGGCGATTTGGGCGCTTTCCAGTTGTACGGTAAATTTTCCGACTTTCAAGGTAGAAAAGTGTAGAAAAATCGAACTTACTTCTTAAAACTCGAAAAAATCGAATTCTTTCAGGATTCGGCAACTAGACGAGCTCCTAACCGACAATGTTGAAATACTGGCCAGGGGCCGCAGCCGCACACGATTCTTCTAGAATTCCAGAAAAGACCGACGTGGCTATGATGATGTTCTATTTGGATTTAAACGACGAGTCTTATACACCGTCAAAGCGCAATTTTTGGCTTTTTCAAACGAAAAAATACAATAAACCCTGAATATCCAGTTTGTTTCTCAATTTTTGCCTAAAAAACGGCTTTTTCACTCGCTTATCATTTACAATTTGAACAACAAGTTTTTTAAAGGATAAACATGAATTTCTAGCTTTTTCAGAGGTTTTCGATTAAAAAATAGAGATTTTTGTGATATCGGACGGATAAATTACCAAAGCTTGCTGTCGATTTTTTTAAATATTTTTTACTTAAAAATCTGCAATTTTTTTTTTCGAGGAAACATGTGAATTTCAAGCTTCAGAGATTTTCTATGAAAAAGGTTCGTGCCGAGACCCATGTGCTTTAAACTTCAGAATTTTCCCAATTTGAAATTAAAAAGAGAATGAAAATTGTCATGGAAAAATGCGTTTTTGGCCCAAAACCTCCAAAACTTCGAGTACAAATATAGGTCGAGTTTCAACTGTTTTCGATCAATTTTTTTGCAGAATTCAAGTAAAAATGGGTTAGCACCATCTCACGATATATTTTTCCGTCAAACACAAACATTTAACGAGCCCCAGGGATGGACAATTATCGATTTACGCGAGAAAAATGGGAAACCGAATTGCGTTTTTTGGCTTCAAGTATTATTCAGAATGATCAAAATGGCAGAGATGCTCATATAACGTAGACGAATTGAGAATTTCAGAACGAAAATTGCCGAAAAAATAGAAATTTTAGCGAATTTGAGTCGGAAATTTCGAAATGATTGACATTTTTAAGCAAATTTCCAACTAAAATCTAATATGCAAATTTGATCTGTTTATATTTTTCTTTAATTGTTCTAAAAACCTTAATAAACAATTAAAAATTGAAGTAAAATTAATTTTTTAACTTTGAAAGGATTTTTTGATTGAAAATTTTCACAATTTATTTTGTGGTGGGGCTAATTAAAATCGTTGTTTTTTTTTTCAAAAAAGTTAAAAAAACTTTAGTCAGAAATTGCCTTGTAAAATATGTTTTTTCTCTAGACCTCGTAGTCACGAGGACGCGTAGGTCGCCTCGCAAATTTGAAAAACTCAAGAAAAATCAATAAATTTGTGATTAATCAAGAAAAAAAATTTAATTTCCTGGTCTCAGACACGAATGCTTCGAAAAAAAAAAAGAGGCGAGCCTACGCTAATATAGTTGACCACGCCCACAAAATGGGCAAATCAAGTTTGGCACAATCTTTCAAAAAATCGAAACAAAAATTTTTCCAATTTTGTGAGATTTTACGAAAATTTCCGTTGGAAAATCGAAAAAAAATATTCTCGTTTTTTATTTTTCAAAAAAAAATGTGCCTAAAATTCATAAAATAAATCAATACTTTCTCAAAATTTCAACAGTCCATCTTCCAGGCACGTTCAAGAGTCCTTGGACCCCATCAGGCGATGTCTCCACGAACGAATCGAATATTCACGGGAGAACCACACGGACCGATTCCCGATAAAAATATCAATTTCGACGGCTAGGATTTTGCCAATTTTATCGATCACTCACTTCTTCACTTCGTTACATTTATCCGCCTCCAGTGATTCCAGATAATGAGCCAGTTTTGCATTGAAATTTAGTGCGAAAGGCCATATAGAGCATGATTTAACATAAAATTTCGAATTGATAAACAATGGAAAAACATGGTGCTATGATGCTTTTTTAACACTTTTAATTGTTCCAATTTGAGAAGTAAAATTTTCAGCTGATAAATCAACTGATTTTCTATATACCTCTGCCACTAAAGCTTAAAAACTTGCCCCAGTGCTGTCCTAACCTTCAAATAGCTGGCAAGTCTATTTATTATTCTTGTTTCATACTATTGAGATTGCTTCGCGAGACCCCAACCCATTTACCTGTAGTTAAATATACGAATAATTATTTATATATTTTCTTTAAATTTCCTTAGTATACTATTTTTCTGATCTCTCTTCAAAAAACGCTAGAAAAAATAAACAAATGTCGGTTTAAAAATGCCCGGTAATTTACCTTCTATAGTTTTTCGAAAAAAAAACCGATGAAATTCAGATGGAAATTCCCGATCCCGAACTGCCGGGAACACCGGTTGGTCCGCAAGATTTGGAGATTCTAGACACGCCCGGTTATACGAGAAGCTTAGTGCGTTTCGTGTCGGGACCCGGAAATTTGACATTTTTGGCGCGCGGCTTATTAGAATAACTCCAAACCTTGTCAAAGATGTTTTTTTCGAATTAAATAACATTCGTGCTTGGGCTCGGATATTCACAGAAATTTTGATTTGGAAACAATTTTTTTTGAGGCCAAAATTTTCAAAGTTTGTCTTGTTGGCGCGTGGACTAGTAGGAACCGCCCCTTCTAAATTATCCCTGTATTGAGCAAGTTTTCTGACATTGATTTCAAAATTTTTTTTTAGAAATTTCTGGTTTATTTTTTCCGGTTTTTTTCCGAGTTGCTGTTTAAGTTTGGAGAAATTTCAGAATTTGTCAATTTTAGGTGCGTGGCAATCTTTTTTCAGTAACTTTTTTTTTATTTGAAAAATTGAAACTTTCGCGATGCGGTTCAAGTAAAGCCACAAAAACTCAATGATTTTTTCACAAAAATTTCAAATTTCTTGCAAGACCTACTGCAACTTCGATTTTTAGAAAACTTTATGCTTAAGAAAAAAAACAGCGCGAATTTTCTGATTTAGCCCGACCCGCCCCAAAAATGGAAAGATTTCCGAAAATTCGAACCAAAAGTTCGCAGAAACTTGAATTTCTCTCACACAGAACGCGCTAATTTGAATTTTTCCAAAAATAAGCAAGCGCCCGCCCCAAAAATGCACAAATAAAAATTTTGAACCAAATAAATACAATTTCGCTTTTTTCCGTTTTCGAACAAAAAATTCTAAGTAAATCTATGGTTCTCAGGGCCCAGGCACCCATCTACCTACTTAAAAAAGCGTTAAATTTCAGGAATTAGCATCAACCGAACGCGCGTCTCGCAGATTGTGTAGTCTCTATTTGGGCGGAGATCTCGAAAAAAATCTATCGCTGCGATCAGAGATCCGAAAAATCCGTGATTGAAGTCACGATTCTGTTGGAATGGGAACACGGACCAATTCAAGCGGCGAAAGTAGTGTAACAGTGCTGAAACCTATTTCGGAAAAATCAAAAGTTGGTCTCTTTTTAGCAAAAAAAAATCGATAAATCGATGAAAACCGACAACTTGGAGAATTTTCATTTATCTCAAATTTGAGTCCCTCAGCGCCATATTGTGTACTGTAGGTGCTCGAATGTTGAATTTCAAAAATTGAGAACTAAAGACATCAATGTCGTGACGAGACAATGTTTTGAAAATTTTGAATTTCAATGTAAAAAATTGGGAACTTCCCTCCAAAAGGTAAATTGGTTTAGTCACAAACTCTGAAATTTTGAAATAAAATTTTTTTCGGCTAAAAATAAGTATTTTACTTTAAAAACTATTTTGAAGAAAAAAAGTTGGGTCTCGCCACGTTGTATCTTGTATATGTGTATCTAAATTGCCATGTTGTCGAGACCCTCTCCTATTTTACACTTCAACTTGTTCCTCACGAGGGACGAGGAACAGTGGTTTCTAGGCCATGGCCGAGGGGTTTCCGACAAGTTTCATCGGCCATTTATCTTGCTTTGTTTTCCGCCTGTTTTCTTTCGTTCTTTTTCCCATTTTTCCTTAGTAAAAAAATAAATATTTTTGCAGATGCCAAACGATTTTCAAGTAAAAAAATCATGTATTCAGTGGGCAAGCAGCGGTATGAAAGTTAGGGCATTGTTGATGTATTATCTTACGGGAATACAAAACCTAAACTTTTGCTGAAACATGATACATATGATGCTTAAACTGACTACCTGATCTTCTTAACGAGACCGCTGAAAAAGTTTTGAGGTTTTCAAAATTCAACTTTTTGTGCGAAAATCTCGACTTTTTCACCGAAGTTGAATGGAAACCTCAAAACTTTTTCAGCGGTCTTGATATGAAAATCAGGCCACTAGCTTCAGCATCTAAGCATCATATGTAGCATCATGTTAAAGAGAAAGTTGTTTTGTATCGTTCCTGTAATCTGTGGCATCATATTACATTGCCCACTTTCACCGCTACTGCCTGCCCACTTAATACATAATTTTTTCACTTGGAAATTGTTTTAGCATCGCAAAAAATATTATGTGTATTTATCAGTTTTATTAAGAAAAAACGAAAAAAATCAGTGAAAAACGAAAGAAGACAGGCGGAGAACAATACAAGTGTGGATAAATGGACTCTGGAACTTATGCTCGGCCCATCCGCCATGGCCTGAAACCACCTTTTCCTTCGCCTCGTAAGGAAAAAGTTGCAGTGACACTTTTACTCAAATAAAAAAACAAAAACCGATAATTTCACCATTTATCAGGCACATCTCTTCCTCACACCGGACCTTAGTGCTTAAAACGAGGCCAGTTCTTCCACAGCGAGCCGACGAGATTCATCGGTCTCCAGCACATGAAATTATACATTTTTGCTGACAATGTATTGATTAGTGGGTTAGTTTTTAGTTGTTTGCATGGGTCAGACTACAAACGAAAACCCTAATTTCAGAGCAAATTTGACGGATTCTTATTTTACTAATCGAACGGAGCGATATTACGTTCTATTCAGAAAGTGCAAACCATTGGCAGATTTCTTCCACGCAATTATCAACATAAGCGTTGTTGGTGAGTTGGCGATTGCGCTCCACCGACACTGGTCAGCTCGCTTGAACTGATAACTTTATCTAAAAAATTGCAATAATTGTTTTAATTTGGCTTCAAAAAACCATCAGTAGATGTAATAAAATTCTTCTCAAAGCAAAAAATTAGATACTTTCTAAAAAAATTGAATCTCCCGCGAAAATAATTTTTTGAGAAAATTTGAATTTTTCACCTAAATATTTTTTTCAAGATTTTTTACCACAAAATGAGGCGGGGCCTCGGTATACACGCTCAAAAAATCAAGGGAAAACTTAAAATACTTGTAAATTTGACTACCAGCTATTTTTTGCGAAACAAAAATCGAAAGTAGCACTTTTCGAAAAATTCTCGACAAAAATGAAAAATGGGGGGGCGATCTGTGTGCGGCGGTATTCGGCGGCATATGCCGATGCCGGTTTTTGGAGCCCGTCATATGCCGTTATGCCGATTTGAAGATTCACGGCATATGCCGAAAAAGCCGTTATGCCGAAAAATCCCCCGATGAATGCCGCACATGTCTGGGCGGGACTTCAAAAACCACGCCCACAACAGAGAACAAAAATTTGGAGTGACGGTTTGCAATTCCCTCGCGCTTTTTCTTGTTTTTTTTCAACAAGATGAAAAAGCGCTCTACTGACACATTTTTTTTCTAATATTTTCATTATAAATCCAATTTTCAGCCGACTCGAGCTTTTCATTGTCGAAATTGAGCAAAACTGGTGCCGAGACAATGTGATGTGCACACATATTTAGGTAATCTGAAAGGATGGGTAACCTGAAATTTTTCCAAAAAAATTTAACGCTTCGTTCGTCTCATCTCTACCGATGCTCAAAACACGTGTGAATCGACTTAACGAAAAATACAAAGAATCGCGAAAAACGTCGTCGAATTGCATGTCTGCTCACACGTGGATTTACCCCGTTTTTCAAATGGGGCATTTGGGAATCAGGAGTTTGAATTAGTAGTTTGCAAAAACTTTTATCACTGAAAAATCCGGAGCTCAAAATGACGATGGCTGCGGGATATTTCAATTTGGCTATCGAATTCGAGATTATGAGGAATCGATTCTGAAAGAAGGAGATTAACATTTGGATATGAAATCTTACAGCTTCTCCTTTTGTATTTTTTTGGGAAAAATATCTGAAATAAGTTCAAAAATTTCAAAATAGAATTTTTTCGAAATTTTTGTACTCCTGGAAATTTTGGTTAAAAAAAGTTTTCTCGAGAAATTTGATTTCCCGCCAAATTTTTTCTGTGAAAATTTGATTTTCCAACATGTTTTCTCATAAAATTTGAATTTCCCGTCAAGATGTTTCTGAGGAAGTTTGATTTTCTCATCAAAATATTTCAAAATCATTTCCAGGCGAACGGATTCTTCGATCAAAGTGGCTTCTCGGAAATAGATTCCACCACTATATTCCAACATTTCTGATCAATTGAAAACGAGAAATCAACGGCCGATCGAGTGTGAAAACGTTCGAATAACGATAGAGAAGAATGGACATTTCATGCAAAAGGTTTTGTAACGGCAGAAAATAATAATCAATTAACGACATTAATTGGCTCATCTAATTACGGTTATCGATCGGTTCATCGAGATCTTGAAGATCAAGTGATGGTTGTTACAAGAAATCGGACACTTATCTATCGATTAACAGGAAAAGAAAAATCTATTATTCGAATATTAATCGATACTTGACATGGCTGCACTTCAACAACCGGAACATCATAATTCCACCATTAGTTCGAGTCATTTCACGTCTAATTCGGAGTTTTTTGTAGACGTTTTCCAATTCTTTATAGCGGAATAATAAGGTTTGACTTTAATAAATCTTTGTAGATTGTTACAGTTTTTTTGAAATGCAACATTTTGCCGAATTAGGCCATTTGACAATTTTTGGTCGTGTCACGGCGCGGAGTAGAAAACTAAGTATTTTGATTTGTTTTTTCGAAATATCCGAAAAACAACAAAAGGAGTTTTTTGTTGAAAAAAATGTTGCGAATTTCAGAATACGGCACTTTTCCGATTTCTGCCCCCTAGGGCTGTTATGAGGGGGACGTCCCCTATTGGGGGCCGGGGACGATCATTTGTACCCCCATGGGGGACGGGCGCTTGTCCCCGCCACGTGACGGGGAGCGCCCCTTGTCCCCGATGGAACGAAGATTCGTCCCCTTTTGAGTTCTGATTTATTTTAGATTTTCACTTCATATCTTACCGGTACAGAGAGTGTAGATAATTCGTTAGAGAGTAGACGTCCGGGACCCAATGGAGCGGGGCGCGCGGAAGAGACGATCTAGTGTCGATTTACGAAATTTTCAGCAACTCGTTGTCATCATTTCGTAAATCCACACAAATCGTCTCTTCAGCTTGGGTCCCGGATGTCTGGCACTCTAACTATCTACACTCTCTGTACCGATAATAAAATATTTTTCCGTGACTCGTTTCCATAGCTTAGACGCTGTGTGCGGGGATACCGTGGATATTCCACACAAAAAACGTGTCGCTTTAATAATTATGAAGCAAAAAATACAACAAACGCACATTCTTCACATTGGGTAAACGAGGGGGCGCGCTCCCACTTTACCCGGGCGCCCCTTTTCGGGGGGGGGGGGGGGGCGTATTACGGGAGGTTTTTTGAAAAACTTGGTAATTTTTGAAATATGTCAACTGACAGCTGTCGTTCAAGTATGTATTTCTATCATATCTCCATACAAATCATAGTTAATTCTTTAGCAATATTGGGGTCCCTCACAAAGTCCAAGTTTTCTTCTCACACGGCCGCCTTCGATTTTTTCTTAAGAGCTTCATTTGCGAAGATCAAAATACATGATCGACAAAGTTGAGTCACTTAAACATCATCATGTGTGTTCGCCTGCAAATGTTAACAAAGGACCAGGCGAATTTGCCAAGCTTTCACGTCTTCATGTCTACGTAGAAAATGCAGTCCTTGAAGAAGCCACGCAGACAGACAGGCAAGTACATAATCAGTAAATGGGCAAATAGGCAAAGCAGGCATGAAATAGGTTAGGCACGTGGGTAGGCAGGTATGAGACATACAAACATGCAGGCAGGTCTGAGAAAGCGAGAAAAGGCAGGTGAGCATGATGAAGGCACATAGGCAGGTAGGCAAGGAAGCTCCTAGACAGGTACAAAATAGATGTGCGCAAAGTAGGCTGCAAAGAAACTAAGCTCGTCCCCAGGCATGAGGTAAGCGCATAGGCTTGCAAGTAGGCGAGTAAACACGCGGGCATCAAATTGAGGCAATCAGGTATTTTTGGGCTCCATTTGGAAACACACTTACTGGATAGAAAAGAGTGGGACTCGTGTAGAATGCAAATGCTATATAAATTGGATCCGGTGCAGCACAGATTTTCTCTTTGATCTCGTTTGTTCAATCCGTAACTCCGATAATTGATTTCTCCAGTTTCACTTGTATTAATCGCTTGGAGAGGCTCTCGATGATAGAATGAAAAATACTCAGAAATTGTCGGATATGTTCTCGATTTTCAGTGAATTTCCTTAGAGAAAGCTAAAAACTCACGAACAAACGCTGCCGATCGAGTCCACCACCAGTATTGCCTACGCCCCACAAAAACCGGTCTCTCGCTGTCTGTCACTAGTTTCAACAAATACCTAATCTCCTCGGCATCTTTCGGTCCCATATGCTCCGGCCATCCGGTATAATGGTAATGAGTCCCCTCTTGAGTACGCTACTTTCTGGAAAAAAGTTTGTTGCAGGCTACCTTTTAGGCCATACTGCATGGAACAAAAATACGGACAGGCGTGGAAGGTTAGAATAGTGATGAGAAAAAATGAAAACAAACATTTAAAAAAGCAAAGAATTGACCGGTTATTATTAAAAAATAAGAATTTTTATCCGGACAATTCGAGGCAGATGTGACTGCCTACCGGCGTGCCACCGCGCCTATCTCATGCCTGCGTGCCTTTACTGACTCCCAAATATTAGCAACAATTGTGACCTAGTCTTCAACAAAGGGTTCGAGATACTCTTCGTGCAAGCGATTGTTAAGTCGCCAAAATTGGTTTTTCGTCGAGTTCAGTTGGAAAGTACCTATCACAGTTCACCGTATTAGCACCAATAAAGTTGAAAAATACGATAAATGGATTGAAAACGAAGGGTGGCTTGAAGGCAGGCAGGACCACTGCTCTGTGTAGGGCGTCTTGTAGACAAGCAGACAGGAGTGGGTCACCATGTAGGCAGAGGGAAGGGTAGGTTGGCTAGTGGGCGGGCAGGCGTAGGCTGCTGCAACACAAGCATATAGGCTCATCTATTTCCGCGAAATCCCACAACAACATCACAAATGTACTTGATTTATTCAGCTTCACTGACTCCCAAAATGCGGCAATCGCTAAAATATCGGAGCTTTTCTTATCAACAGGCTCAACTGCGGAGCAGGCATCAACACAAACTTCAAGCCGTTATCCACTTCAACAACATGTGACGATGCTGGCTGAAAATGAACGGATTTTTTGGGAGGTACCCATAATGTTGCCACTTGTCTACCTATGTGCGCTTGAGTTAAAGGTTAAACCTAAGCCTATGCCTATGAGCCTAAGCTGAGCCTAAGCTTAAGGTTAAGTGTAAGCCTAAGCGTAAACCTAAGCAATGAGGCGAAGGGTAGGCAGGCAGGCGTACCAGTCTTACCCATTCTTTTTCGAAGACTCATAGACACCGGATCACAGTGACATCCTGTAAGGCGCAAAACTGGACAAAATCGTCTCCCGTAATTTCTACTCTAGGTTATTTGGAACCTTCTCAAATACTGACAATTTTTTCTAGTAACGAACGAAATTAGCGTGTTGAATGAGTCTTGAGCGGCCGAATTGAAAAACGTATCTCATTCAGATCCACACGACTGATCATCTGATTTGGTGGGTACATCGTTTCTCTTTTTCTTCCGAGTCGAGTATTTTGTAGCGGAAGCAAAAGGAAGCAATTATATATGACAATGACGATCAGAGCCAAAATTACATATTGTTCGTGTGGTCTGGGATTTTGGAAATTTTTAGGGATGTTCAGCTTCTAGGCTTTGTTAGCTTAGCTTAGGCATAGGCTTAGGCTTCGGCTTAAGGCCTAAACACAGAGGTTGGCGGAACCAGGCAGGCAATATTAGAGGTACCCGCCAAATATCTAGAAGCTTCACTAAAAAAAAAACGTTTTGAATCTAAGCATGAAACCAATTTTGAAAAAGTAAAATGTTTGCTTATCTCAATTTTTGCATTTCCTTGCTTTTATATTGTAATTAAAAATAATAATTTGAATTTTCAGCTCGTTCAGCGATAGAGTTGTGCTAAATTTCAAGAAGAAATTAAGAATTTTCGTAAAAAATATTTGTTAACGCGAAAAAACTTTTAAAGCTTTAATTCATATTGTTCAAAAAAGGTTGGAGTAAAAAATTTGGAATTTTTTTGATTTTCACCCCAAAACCTTTCTTTAGAATGTATCCCTCTTGCCTCCATCCGCGCCTTATACGCAATCCGCGCCTGATGATTTTTCTCCGGGAACTTGAGAAAACCGATTTGGTTGTTGGGAGAAGAAGTGCGGAATGAGGAGCGTTTTTTGAGAAAAGATAAAATTTGGGATTTTTTTGATCATACTTTCCCGAAAACCTTTCTTTAGAATGCTCTGCCACTTGCCTCAACGCCTTGTGATTTTTCTCCGGGAACTTGAGACGATTTGGTTATTGGGAGAAGAAGTGGGAATGTGGAGCGTTTGCTGAGAAAGATAGATTTTCTACTATTTCTCAATTATTCAATACTATCGAACTTGATATGCAGTCTTTGAACGTTCTTGTCATTACGAGTAGGCGAAGGTTATTGGTAAGTGTATGGGATGTCTTTCCGATGAATTTTACCAACGGCACGGGATGCCTGAGTGTACCTTTTCGATTTCATAAAAACTTCGGAAGGTGTGCTGAGCGTAGGCGTAACTCGTTAAGCTAATTTTTCCTTTCCTGGTAAATCTTATCCTGATCAAACCAGTTGGGAACACTGTGGCGCCACGTGCAACTTCATGGGTAGGCGGCAAACACCACGGAAATTTATGGATTTGGGGCACCCAATTTGACGTAATTTCGGTTTCCGAATTTTGTCGGTGCATTAAGGGTTTGACACTGAAATCGAGTTTGGGAATTAGCGTTTTTCAAGTCGAATACCCTCAAAATTTTGGTTTCCGCAAGTTTGTCTAAATGCAGGGGTAGGCGGCAACTGCCCTTTGGCATATTTAATTTTGGCACGACGAATTCACCCAATTCCCGTCAACGTGAACTTTCTTCTCGTTTCTTAATTAGTTTTTCATTAAATTGATAAAAATGAGAAAATTATAAATTTGTAAATTCACTTCAAAATGCAGGCGGGCAGGTTTCAGTCAAGCCCGTCTGAAACCGCGCCTGTCTACCAAGGAAGCCCTACACCTTTCAAATAAGATCAACTCACTGTGGTGGTGTGGACCATTCTTTTCAGAATTTCCAAGATCTGGCGGTGGTCGGAGAATTGCAGTCGTGGCAGAGGCTTGAATAAATATGAAATGAGCAAAGCAAGTCCAGAGCAGCAACAGGGAGCCTTTTTCGGCAAGTCTGTTTTGAAAGACTTGAAAACTCCAGTCCACCATCATCCAAGCTCGTCAGAGCATCCTGAACTTCACCGAGCAAGCGACTTCTTATTGCCAACATCCTTCACAAGTTCTACCGGTTTTTCCCACGATTTTTCCAAGCCTACCCTACCAAGACTAGCCCAAACAACCTTCTTAGCTTCCGTGAAACATAACCATATCTGTCTACAAATTCTGTGGAATCAGATTAAGTCCACTTATGCATCTAAGCTGAACAACATCACATCCAAAGATGCTCCAAGCGCCACCTCAGCTTCTCAAGATGATCTATCCTTATCGTCCTGTGCCAAAGTGGCTCCACTCGCTGCCAACTCTCGTTGCACAATTTGTGCATGGTTCTAATGATTCCACATTTGCTCTTTATTCTCGGAGCACGTCCTCCAGTCGAGCAATTTCTTGAGCCGCTGGGCCATTATGGAATTAGTGTTCAGCGCCGTTTGTAAACTGGGATGTTTTATCCGAAGCAAATTTGCGGCGCTTGCTAAACGTACAGCGCCAGAGATTTCAGACCACTATTGAGGCTTGAAACTGAGATCAGAGCATCTTCGACAGCAGTGGCTATCGGCAGGAATTTTTGATCTGTTCGGAACGAATTCAAATCTGACAGGTTCTTTTTAATTTTGGCCAATTCTTTGTTGGTCGAAGCCAGCTCTACGTCGGAAGAAATTGACCAATATCAGAGCGAGAGTCATTCATTTGTTCAATAGCACGTTTTTCTAGTGTTTTCAAAAGATTCGGATTCACGAAAGTAGCGTTTGCCGTCAACAATTCTACTCATGGTCAGCAACAACATTAGCCGCTCATTTTTTTCACTCCATTAAAGCATGGGCGAGCCTCAGCGGTTGTCCAATTGCTATTGTTATCCTTGCAATCAGTGCGCATTCTGCGTCCTGATTTGCTTTCAACAAGTTGATTCATCACACTTTCAAAATCGATATCGATTGTTCCCTCAATGTTCGATGCAATTTTAGATAGTCCCTCCAGAGTCGTGAAGTGGGGGGTTATTAGATCAGAGTAGATTTGGCGCATTGGGCTGAAAGTTTATTTGTATTTTCGTTTTTTTGAGTTTGAACCTTTCTGGACAACCGACAGATTGGCTCAAACTAAAGGACTTTACAAAAGTTTTTGTCAAATCAATTTCGCAAATATTACCGGTTTTTCGGAGCTTTGATCAGGGTGGGGTGGCAAACGATTTTTTTCCCGAAATCGGCAAATCGGCAACCCGGCATTTTGCCGATTTTACCAAAATGGCCTGGAAAATTTTTGAATCCCTCCCTCTAAACACTTCCGGTAAATTGTTATCCAAACTACAATTCGGCAAATTACCTGAATTAAATCAATTTGCGCCCAATCGGCAAATTGCAAACTGCAAATTACTCTCCGATAAATTTGGAGAAACCGGCCAATCGCCGAAAATTTTTGGTAACTGGAAAAAATTTCAAAAGGCACTGTACCCTTGCTTCCGTTTTGAAAAATGCTTCTAAACAGTTCCGGCATATATCCGGCAAACGGCAAATCAGCAGTTGGCCGTAAAATAAAAATATCCGCCTCAGCAAATTAAGGCTGGAATTAAAAAGTTCCTCCAAATCGGCAAAACCGGGAATTTGGCCGCGTGACTTCGCCAAAAATAAATATGCCAAACGGCAGTTGCCACCTACCGCTGCAATGTTAGACAAACTTTCGGAAACCAAAATTCTGAAGGTATTCGACAATTGTTTGAAAAACCCTAATTCCCAGGAACACGACTTTATTATAAAACACTTAATCGACAAAATTTCGGAAAGGCCCGAAATTTCTGGCATATTGGGCAAATCGATAAACATTTTTTTCCGTTGTGCCGCCTACCCCTGGAGTTGCACGTAGTGCCACAGTGTTCCCTATTGGTTCGCTCAAGAAATTGCGGACTTGCCAGGCAAAATTAGCTTAACACGCCGAGTACCTCGCTTAGCTCACCTTCCGAAGGTGAAATCGAAAGGGTACACTCAGGCTTTCCGTGCCGTTGGTAATTCATCGGAAAGCCACGCATACACTTACCAATAGACCTTCGCCTCAGCGACAAGAACTTTCAAAGACTGGATATCAAGTCAGATCGTTCGATAGTATTGAATAATTGAGAAATAGTAGCAAATCTATCTTTTCAACAAACGCTCCACATTCCGCACTTCTTCTCCCAACAACCAAATCGTCTCAAGTTCCCGAATTTGCGTAAAATTATGTGATCAGTACTTTCTCGGGCCCGAGCGTCGGTTGCCAATTGAGAGTTTAGGTTATGCTCCATATCAATTGCTCCATTCGGTAGACCAACTGTGTACTTCTTCGGGACTGCCCGATGGATTCGATGGTTTGAAGATGGATCTTCGATTCTTGGATATATTTGGAAATGCATTCCGGATAGATGCCATGTTTTCTACTAGCTTTCTTAGTGCCGCGATTGCGGGATCCCAGATGTGTACAATCTTGATGGGTGAAAATTATGAGTTCATCACATCACGAACTTTTGGCCATAATACAAAGAAAGAGGAGCAGCTATTGTTTTTGAAGCCATGCATCGTACATATTCGGATTCCCACTACAATCTTGGGATTTTTTCAACAAATCGTTTAACGCAGAATGGGATTTGGGAATCTCGGTAAACTAGTGAACGCTTCAATCTCTATGTACAGTTGCTCCATACTGAAAGCATTTCGGAAAGGGTTGTAACTTATGTAAAACTCTCTGTAATGTCTTTCATGTCTGCCTTGAAATTTGTCTCGTCTGGCCACTTCTTGGGACCTCCAATATCATGAGCCAGGTGGGGGTACCACACTTTTGACAGTTGTAAGGCCAGAATTGTTTTGCATCAACATCGTCGCCGATATTCGATTGTAGTTCTATAAAGGTATAGTTTTTGGGGGCAAAAAACGAAAGTGGTTCAAAATTTTGGAACATAATGCCTATTTTTAGATAGCTAAAATCTAAAATTTTGCATTGCTGACAAGCTTGTGAAAATCGGCTTGTTTAACAGAAAATAGGCTTTTTCCTATACTTTGAATTACTTTTTTAGATTGAAATTAAACTCATTTCGGTTATTTCCAAACGTCCACAAAGCCGCAAACTCTATCAGGGGTAGGCGGGAATTGTAGGCAAATGTATTTTCTGCAAAGCTAATCGGGATGTGTACAATTTTGCCTCTGGCAGTTTACCGAGCCCATTTACCGAAAATTTTAATTCCGGCAAATTGTCCATACTCTATTACTACATAGGCCCTTATATAACATCTTTTTCCGCCCCTCTACTCTATTACCACCTAATCTGTTACTACAGTGGATTTTTAGAAACCAAAATTTCAGCTTTTGAATTTTATATTCGTAGAGATAAGAAATTCGTAGTGAAAAGTTGAAACCTGGAACAAACATAGCTGCATAATTGCATCGTAATATGTAAAAATAGGTCTTCCTTGGTAGATAGGCGCGGTTTCAGGTGCGCATGCCTGAAACCTGCCTTGGGGCCATATGTGAACGAGTAGACTGTAGTTTTAAAAAACAAAAAAAGGTACCTAACAAAAAACATTCTCATATATTAGTTTGAATGTGCAACCAAACCTTTGAGCGCTATCAGTTTAGAATTTCCAGCCAGAACTGGAGTCAATTGCATTCAGTTGATCCATTGAGATATCGTATTTGAACAAATCCAGAGTTAAATTCGTTGATGGAATGGTTCCTTTTGTGCCGTTCAATTCTTGTTGTAGTTACATTGATCTCAATCGTGAGGAGAATTGTAATCGTGCTCAACGGCAGTTATGAAGTTGTCATCTGCAACTTTTATGACTGATTTTTTTAGATGAAGTTATTTGTTGTCTTTTCTTTTATGAATTATTACGTATATAATACGTATCATGCGATATTGTTTCGCTTTCCAACCCCCGGGGAACTCTTTTTACTTTGTTTTTTTTTGACTTTTATGGACTTTTTTGTCCTTTGCTATTTTTTTTATGAGAATTGATGCCCGAATTTGACTTTTTTCAGATCAGATTTTTTGGAATTTCTTCGCAGAGGAGAATTATTCTTTTTTGTCAAAGCGAGCTAACGACCTAGCCACTGACGCCAAGCCTAACATAGGACTGAACCTTCTAAGTCTGGAAGTAGCCTAAGCCTACAAGGAAAGTCTTTGAAAGGGCACTGTAGATTTTGGTTCCTCTCATGTTGATTTTCCGATAGAAGTGTGTGTTTTGATCTATCCAAAAAATTTAGATCCAAGCCAAGTTTCAGCAAAGTAATGACATTTCGAAATTTCAGTTAAAAACACCATTGTGAACTGTCTTACAGTGCGATCCACACAAATAGCTCGCGTGAACACCAAAAATGTGACGCCCACCACAATAGGCTGAAGACAGTGGATTTCAATGCTGTTTTTAACTGAAAATTCAAAATGTCGCACTTAAGTTTGCTGAAACTTGACTTGGGCAGCTAAATTGATTGGTGAGATCTACCCAAAGCTAACACTCTTCTTGAATCGGAATATCAACATGAGAACCCTAAATCTACGGGCCGCTTAACCCAGACCTCCCTTGTTAGCACTAAGCCTATGCGAGACACGCAAAATATACATTAACATACATATACAACAAATACAACGTAATAATTGTTTTTCTGTAATTCGCTGACAAACCTTTCCAACTACGTTGGGAACGTGGATCTAATGGCGGTCATCACATTAAAGAAACTGGATTCTTCTGGAGCAACATATATTGAAGTTAAACCTCCGAAACAGTCAAGAAACCTTCGAAAGTATCCGAATTGACAACACGATTAACCGTTATAATTATCAAAACGATTATTATTGATTCGAAGACAGAAGACAAAATTCGGAACCAAAATAAAAATCAACCTACTCATTGCACCAAAATATTATGAAACTTCCCTTTGATCGACGGTTTTTGAAGCAATTAAAGATTGGAAGTGTGAATTCTGAGAAAAGGAGTGTTGGAATTTTTATTTATTTTATAACGAAAAGGTCACGCGTTTCTGTAATTTAATTTCTATGAAAGTTTTAAGGTCTCACAGAATGTCAAACACTAGATGGCCGAAGAAAATTTGACATAAGCAGCGAAATTTGACCTTTCAAAAAAATTAATATTACGTGTACAAAAATCTTTGATTCCAATGGAACTGAATTTTTGGGTGATACAAGAGGGAATGTGTCTCAAGGTGTAATTTCAGTAAAACTGTACAAGAGAAAAAACGTTCAATATTTTTACGCCGTCTATTGCTAATAACTTCTACAAAATTTTCATTCGGACATAACAAAAATAAAACAAGGTGACCATGGGGTGAGATTACAGGTGCATTTCCTCATCTTCATTTTTCAGACTGAACATCCAAGATAAGTAGCCCGAACTGAAGTTTTTCTGAAAATGTTATATAGTCATTAAACATCGGTCAAAAACAGTATTTAAACAAAATATCCCGAGACAACACACCTTTTTTGTCTTCAAGATATTCAGATAGAAACCTAATGTCCTGAAACTTGGATTTTGGGTCCTTAAGAAGATAAAACAGATAATTAGCTGTTTTAAGTTAATACCCGCAATCATTTTCACATTAGAGCAAAATTAAATTAAAATGAAACTTTTTTTTGGATTCAAGCATTTTTTGGAACCGAAATTCAAGTTTTAGGACACCCTAGTTTTCAACCTGAATATCCTGAAGACAAAAGTGTTTCACCATCTTGGCATTTTTTGTTTAAATACTGTTTATGAATGTTTGATGAGTATTTAGGAACTTTTTCAGAAAAAAATTCGGGCTATTTTTCTCGGAATTTCAGTCTGAAGATGTATGATTTTTTAATTCAAATTTGAGGGAATGTCGTTCATGGTGGCTCGAGGTCAATGGATAAATGGCTAAGACTAAAACATCGACATTGATCGAAGAACGATTTTTTATTCAAAAAATAAGATTTATTTGACTAGCACTGAAACATTCATCGTTTTTTGTCACTATAACCCATTGGAATGATCTGTAGAAATTAACTAAATTTAGAGATTTTACCGATACGTGGCAATATTTAAGACATTAGTTTTCGCCCTGGCCGTTTGTCTGTTGAGATAGTGAAGCGCCAGCTAAAGCGCATCGCCTTTGGTGCTGAGAAGCAGGTCTCGACGCGACGACATCTTTCTTCGCGCGCAGCGGCGAGATTTCGTCAGTACGTGTTGGAGCGTATAAGAATAAGGACGTGATTTTATCGATTTGCATCGATTTTTTTTGGATTTTTCTTTGTTATTGTATTTTTATCGAATTTTTAGTAGTTTTAAGGTTCTTTTTTATCGATTTTCCTTGGTTCCGTTGTGTTTTTAAGCGTTTTTCTCGTTCGTAATGATAAAAAGGGCGGTTTTCTCCGTTTTCCAAGAGTTATTTGGTATGTCAGATTTTGCAGGAGGAATCATCAAAATTCTCAGTTTTTGGCATGTGATCCTTACGAAGAGTACTGTCTGATGCACATCAATGGCTTTTTCCCCCGCAGGTGCTACAGTACGTGTTCTACTCCTTTCAGGGGTTCCTTCTCTCTTCTAGGAGATTAAATATGTTCGTTGTTTCTTCCCTCTATCTTACGCGCTCTTTCCAGCCTTGTTAGTTTATCCATGCTCTTTTCTTATGTAATTTTCGTTTATCAATTTCTCTAATTATTTTCGGTTTCCGGTTCGTGCACTCGCGCACCCTCTCCCTATTTTACTCTATCTCTCACTATCTCTCACATCTGTCTCTCTCTCATAAGCTATTTTGGTATTTTGCGCGTTAAGAAGTCATGTTTTGATGGACCGTGTTCAAAGGAAGAATATTTTCGGCGAGTGCAATGTATGTGGTGTGAAGTCACTCCATGAGTCTTATTATTCCGATAACCTTTTATCGAGATGTAGTACCTTATCGAGCGGCCCAATTTTATGTATGTTTATCTACATTGTGGTTACCATGTAACGGGAGTTCACATCGCAGGAAGTTCTTTATCGCGAAAGTATCAGACCCCGGATTACCTATCAGTTTAAATGCGACATCTTTCGTCGGGTGAGATATAGTATCTTGTGTTTCTATCGCATTTCATTGGACCGGTCGAGCCAGGTCTGAGTGTTTATGAGCACGAGTCGACTCCGTGAGTCTCAATGATTTTCCGTTTGCAGGCGGTTTTCCAGGTTTCCCGTTGGTTTCTGCTTCATCTTCTACTACCGTTTTAAGTAGGATTGGCTCAAGTCTACGGAAGAGTAGAGCAAGCCTACGGTGTAAAGAAGGTCTTCGAAAGAGTAGCGCAAGTTTACGGAGGATTCACGCAGGTCTACGGAAGAGTGGAGCAGGAATACGTTAGAGAGTCACTAGACCATACTGGGGGTCCGATTTACAATTGGATTCTCGAAAAACCGTGTACCTGCATAACCAGACAGCCGATATATCTACCTTACCGTCCAATTGGTCAAGTATTTCAGGAGAAGCGTATAAGGCTATGATTTTCTTTAGCAACGCCGCGCGTTTTGTAATTGCATAACAAGCTGTGTATTCCGTGTAGACTTTATCCTGCTCACTTGTTAGATGTTTAGGGACATCCGGTTCGACCTTTTTTCTTTCTCCCGCTATCGACGACGCAGATCACTGCGTATGAGTTGCTTTTATATACGTCGATCGATTGTTCCGGTATACGTAAAATTAGGCGCTATATTTTATCGCTTTCCTTGCTCACGCGATTCAGATATTTTAATGTCGAATTCCGTCACCTACCACTACGTAGGAGATATGCAGTGCTTTGTCAGAATAACTCAGGTCGTAAGAGTCTCTCAAGACTAGGGAGATATTCGCAGGTTGGTGGCAGTAATTTGTTTTTCCAATTAGCTATTCTCCTTGTCAGGACTTATTCAGGGAGTCGAAGTAGCCCGAGACGTTTGGCCCTAGTATGGATACTTCACGACAGTTCAAACAGATTGTGGTCGGCCTTTAATGGGAATTAGTTCTACTGCTCAGGTTCATAGCTGACTTAGCCGAGCCCCTTCGAGGTACGTCGCAATTTGGCGATTAGCATACTTCCAGGAAGACATAGACGAATCACAGTTTCAGAATTCCTATACACTTCGGTAACTACGGAGTAAGGCGATCAGTTCCTTGCCGCATTTATATGTTCATCTGAACTTTATATTTTTGCATATTAGCTCACGGATTACATTGGAAACTACAGATAACTGGGAGACAAATGCTTCGCTTTTTGTCACTTTTTCCGAGTTTACTCAAGCCCAGAGTAATGTAGTTTGAGGTTAATCTACTTCTCGTTTCCATGTGCAGATACTAGCAGAGTTGCTGTTATAACTGAGAGTCATTTCACACACAATACGGGTTAATGTCTGTCGGCAGTTTCTTCTCAACGCAAGGTTTTCGCTATATAGATAATCTGGTATAGCGGTGAACAACCTGTAATTATTAAACGCCTCAAGCATAGCCGTGACTAGTTATAGCCCCCGGCTTTGCGGGTTCTACCCTATACCACACAAAACCCAAACCAATAAACTGCACCCATGATAGTATATAATTCGTGTAGTCTTTTTAGAGCGTAAAGTTCTGATCAGGGAAAACGAATTCTCGGGGAACGCGATCCTAGAAATGTTTTCCCGAGAAAGTGAGGCGAAAGCTTAAAGGCGCATCGCCCTTAGTGAGAGGCAGGTCGCGACGCGACGACATCTTACGCGAGCAGCGGCGAGCGTCAACCATTCTATGTGTTGGTTTCCCCCCTCCCGCCCCACACACATATTATTACAAAGTGCGAGACATTGCCAGATATGCGATGATTTCCATCCTTACGGAGAAAAATCGAATTATTATGAAAATATTAAGTTTAAACCGTAAGTCGTTTATTTTCAGGAGGTGAGTTTTATTTTTCCTTCATCGTCGCCTGACTGGGCAGTCGGTGTCTATCTGAACAGGTTCGCAGCTCGACCCTTGTGCTTGTTTTCGGTAGCAGGAATACTTATGGGTTTTTTCTCAGTTTCGGGAGAGATATTTACAGGCTTTCAGGAAACCGAGATTCAGAGTTTAATAATGACATATCTTTACAGGAAAATTGTGGTTTGAGTTTGCAGCCTTTCAGAGCGCCTGATGGATCAATAGTTCAATCCACGGAAACACGGACGAAAGTGGTCCACCGAGCAATCAATGTGGAACGAGACGATTCCAGCGTTTACCATGCCCCCTAACATCGATGATGGTCTAGATATGGTAAAGTTCTTCCCATCAAGCGTTGTTCGAGTTTTGGACAAACTTCTTCGATAAAATACTTGACTAAAAAAGCGAATTAAAGTCTACCACAATTTGAAAAAATATTTGGTTCTAGATTATTTCGAAGATTAGACTATAAACATCACGGCCTAACGTAGCTGAGGTTTGACATGTTGTGGGACTGAATACAAAAGCGTGAACTCACGTAGACTGTCTCTTGAATAATTCGAAGAACCAGATGTGAGCTACGGAATAGGCTTAGGCTTAGGCTTGGGCGGGGCTGGGAGGAGTAAAAAATTGCGGAATTTGCCGTTTGAAGAGCTCGCGAGTCCGAGTTTGGCAAATTTTAAATTTTGCCGTACGGACACACCAAATTTGACAAAAAATCGTCAAAAATAACAAATTGTTCCGAGTTTGATCAGTTCGGTAAGAAAATTATGAAAAAAGTGATTGCAGAATTTGCCAAGCTCGCCTTTGTCTTTGGTCAATTCAGCACCATATGAGTGATTATTATCAATTTTCCACTGTCGCTACTCGTCGCATTTAACAAGTAGTCATCGATTGCCGAAACAACTTCCTTCCAGCTCAAACTTTTTTCTTAGCCTTCATCGGGAACCTTTCCTAATTTTTGCCCGGCCTTCTTAACCTCATTCTTCCCATCTTCCCAAATTACAGTCCCATCCTTCTTCTCTTCTTCTTCCCACTACGACCATCTTTGTCCACGTATAGGACCTTTCTCGGGAGAGTGTGTGCAACCGAGACAATTTGCGAAAAACTGCTCCCGGTCCCCCCATTCGTTTTCGCGAAATCAATAGACACAAAAATGTTCCGTAAAACAAATCTCCCCTTGTCGTTTATCCCCCTGTAAGTACACAATATCCTTTTCTCAGAAAAAAACCTTTGTTCTTCAATTTCGGAATCATCTTTTCTTCGTGTTAGTCCTGTGAAAGGCGGAGTACTGAAATATGGAAAATATTTTTAAAGGACTCCCTGATGAATATCTAGAAAGTTCAAAAAATTTTCCCTCATTTCATATTTCAGCTTGAAATCTTTCATTGTGCACTAATGAGATTTCGACTTCGAAGTTTGTTTGAAATGTGTTTTCAAGGTCAATTTTCGTCAATGTATTATTTTACTATCGAAAAACTAAAAAAATTTCAATGAGTAAAGTAAGTCAGTAAGCATTTGGTAAATAACAAAAATCTCGTAATTCTACACATAGCGTGTCGCGAAAATTCGAAATCTGATGGGTGCACAGAAATGCTTCAAAGTCAAATATAAAATAAGGGAAATTTTTGTGAATTTTGTCAGATATTCGGAATCAGGGGCAAATTTCATGTGAAGTCAATTAGAAACGTATTTATTTCGTGGTACTTTTCTAGTCTAAAACTAAAACTAAAGCTAAGCTAAAGTTAATTAAATTACCATGAATCTAATTTGTTTTGTTTTAAAGTTTCCGATTGCAAAAATTCCAAGATCTCAGTTTGCCGAAGTTTAAATAACGACTACTCTGGACTTTTCCCGAAAGAAATCGAACACCGGAGTATACTAATAAGATCCATCGACGGTACACAAAAGGATCATGAAAAAGGGGCACCGTGCGCATAATACCTTCTGGCTTTCCCCTTCCCCAACGAAAGATTTCCTTCTTATATTTGTTCGTTTCGTTCCTGCACACTGACTCCATCTCTTCTAACCCCCTCCTCAGTCTGAATACTCTCTCATCTCACAACGCTTCTGTCTACCTGCCTGCGTCCCCTCGGTACCATATACTAAGCTCTTCGTACCTGCCACTTACCAACAACTTGCCTCTTGGAGGTCTCTCTCTCTACCACATCACCTTGTTCTTCGACTTGTGGTTCTCTCTTATCGAAAAAGTGACTTTCCCGTGTCCTTCCGGGCCATTCACATTTTCCAATTTTATTCGAATTTTATGTGCCCACTGCTAGCTAGGTTCTATATTGAGTGCCGAATTAATTTTATTGATGGTCTAACTAAATAAAGCCACTGGCAACAATTTTTATAAAATTTGTTTGCATATTTATGTAACATTAGCGAAAGTTTTAAAATTCGTACTGTGTGAGACATCACTTTCGAAGTGTTCATTCTATTACGGGATCACAAGATTATGAGAATACTTATTGCGCAACATTCTTGACGCGCAATAACTAGTAGCGAAAACTACAGTAATTCTTCAAATGACTATTGTAGCGCTTGTGTCGATACTGGCTCGATTTTATTTAAATGATTTTTTTTCGAATAGTGACGTCGATATTCCATTTTGCGTTCTGTCATTTTCGTATTATCTATAATTTTATTCATTTCGAGAATCGAGCCCATAAATCGACACAAACACTACAGTAGCATTTAATACTGTTATTTTCGCTAAGATGCGCGTCAAGATTCATTTCCTTACGAAATACAAACTTCTTGGCGAAAATTTCAAAATTCAAATTGCCCGCTTAGTATTTAGCCCGATTAAAGTTTTCTGGAATTTCCTGCCAAATAAAAAGCTAGTTTAAATATTTAAAAAATAGCTTAGAATTCTTAGAATGCGTATTGCGCAGCTTATTAAAGTGACGCCCAAAGCATTTCATAGCGAAAACACAGTAATTCTTGAAATGACTACTGTAGCGATTTTGTCGATTTACGGGCTCGATTTTTGAAATAAATTTTTTAAAATCTTTTCGAATCAAGCCCTGAATAGACACAAGCTATACAGTAGTTATTCAAAGAGGTTTTGCGATCGAGGTATTTTGTGTGTCAAATAATTTATTCCCGTAAAACAAAATACCGCTCTAAAGATATAAAATTTACAACGCCTATTAAGCACCCCACTGAAACCCGCCGGAAAATCCAGAAAAATTATATAAATTTCACCTCTAAAAAATAACCTGGATAGTTGACCGCGTAATTCGACCTGTTTTATTCCCGATTGTCCGACTGACCACACCCCGATTCTCTCGAACTACCCGCGACAAGCTTAAGCATCTTTCTTTATTCCCACACTTTTCGTAAACTTCTGAGAGACAAAACAATAATATTTCTTTCTCAAATCAATATTGGCTATATTCTCCGCATCCCGTAGCCGGTCCCATCAACGTACTTCTAGAACTCCCACGAAATTTCAATTGCTCTATTGAAAAGGTCTCTCTTTTATATGACCCAGGCGCAAAATTTCGTGCAAAAATACAATCGACGGTTTTCTCGACGCGATAATTTTTGCTAAATTCCAAAAATGTGTGCGCCTTTAAGATTACTATTGTAAATAGCTTCAAACTTTAACCGATTTTAACAATTGAATTTTCTATGTTTTCCGTTTAATATATATTTATTTATTTAAAAATTAAGTTGAAATTGAGATAGGCTAGATGAAGATAAATTACATTACTCTTTAAAGGCGTACATGGCGTTTCGCGACCGGGTACAGTATTTTCGACTGCGATTTTGGTTTTTAAAAAACCTAACCAATAGAATTTCCAGCGCTCACACTCATTGGCCGTGGAAATTCAGCAGCAACCGTCCGACAGCTCTTTTTCGTCAAACGACGAATTCGACGATCGTCAGAACAAAAAGTGAGCAGTTTTGTATGAACAGCAGGTGTGATATGATTTTATTGTGAAATTTGGGACTACAAACCCGAAAAAACAGTACACCTTGTGTGATCTAGAAAAAAATAGAGCAATCGATAATTTTCGGGTAATTTTAAAGTTATTTTCAGCGAAATAAACAATATTTTTGAGCATTGGGTTTTCAGTCATTTTCGATTAAAAAATTCTTCAATGTTGAGCTGAAACTATCGATTTTTACTAGAAAATTGATATTTCTAGCGCAACCACAATTTTAATGTTTAAATTGCTTTGAAACCTCATAACATCTCCCGCACCTCCAGTTTTTGAGTTTTCCGAATATCGGAAACTCAACAGAATCTCATTTTCCTACCGAAATCTATTAGTTTATAATAAATTTGATCGTTTTCTGCTTAAAATTCCCTGAAACTTCTGAAAAAAAACCGATTAATCAGCTAATTCGCTTAAAACTAATTTCGTGCCGGGATGACCACGGCCTCGGGTTTTAAATCGTATGCGCTTTTTGTTTTGTACCATGTTTATTATAGTTTTTAAAGTAAAAAATGAAATTTTCAGCAAGTTTTGGCGTCAAAGAAATGTATCGAACGCATAAATTGAACGAATACTGGAGGCTTGATTTCTGGTATAGCGAATGGTATTCTAAGTGAGTTTTATCCGATAATGGGAATCGACGAAAAACCAGAAATAAACAGTTAATTTCCAGAAATGAGCAACGGGAACAGCTGCAATCACCATCACCAATTCCCGATCAGCATTCCAATTTCGTGCTCGTCACACTCAATTCAATCACGATCACGAATGAGGACACTCTGAACGCGAATAGGGATCTCCTGTCTCGTGCGCCTGCAACGACGTAATTGTCGCCAGAACCGTGTAACCGTCGTTTATTCGCGTGGAAGGCCGGCCGGGATAATGTTTTTCTAAAAGACCATGTCAGGATATTGGGAAATACAACGGTATGAAAATCGGCTTTTCAGCGATAAAAATTGGAATTTTCAGGTCAACCCAGCGTGGTATCCCGTAATGCTAATCAGGAGGAGCGTATGGTTCATGCACATTGTGTAGTGAGAATAAAATTGGTTTTTCTGACCTTTCTATGAATAACCCCGATTCCCATGAAAATATAAGGATGTTTTCAGCAGAAACTCCAGGCAAATTGAGTTTTTGATGCGAATAATGGATTAAAAAGGATAACAAAAAAATCCATGAAAATTATTTTTTACATCAAAACTCCATAAAAATCGGATTTTTGAGCGGATAGATTACTTTGCCAGAAATTGCATTTAGCAAAAAACAATTCTTGCGCGCAATTGCGAACAAAAAATTCAGAACAATGAAACATAACAAAGTTAAAAAAATTATTTATTTAAATACTTTTTTGAGCTGAAAATAAAAAAATTGCCTCAGATTTTGTGGCCAAAAATTCAAGAATATTGCATGAAAATTAGTTTTTGTTTGCAGACGAAAGCAAAAATTAATTCTTTTTCTCGCTTAAAACTGGGTTGATAAAATGGTGTTTAACACAAAAATCCACAAAAAATTGATTTTTAGGCCACAAAATCTATGAACATTCTGATATTCTGGAAAAAAATTAAGAAAATTCATATTGATTTGCCATTTTGTTCAAAAACTTTTTTCAAAAGCATTTCATCAGTGGGAAAAATTTGATATTTCAACAAAAAAATTATTAAATTTTAGAGCTAGCCTACGGCCATGGAATTGTAAGACAGACATGAGAGCTAGCGGATGTGACGTGGCTCCGGGAGCAGCTTCAACAACCTCCAGCACATCATCACATCATTCAACTGCAACAAACCATCAGCCATGGTTTCATTCAAGATTAGCAGAGAACTGAAAAGTAACATAGAAAATGTTGGAAAATCTGGGAAAATGTGTCATTATTCGGTTTTGTCGTCAGGTTTCCAATTTTATGAAAAAAACGTCACTAAAAACGACATAATTCTTACGGAAACATCTGAAATTGTTTGCATGAAAAAAGTCGCGATTTTCTAGAAAATTTTAAAATGTAATAGAAAAATGTTGAAAATAGATTTTTTCTGAATTTTTTGAATTTCATTAGATAATAGAGACAACATCATGTTTTGGAGTCAACTTTTTCGCCTGAAACGCTGGAAAAGGCAGAATAATGGTTAGGGTTTTTAGTGGTATCGAAAATAAAAATGTATTTTTTAAAAGAACGAGAATTTTTTTTTCGTCGAACGTTAGTTCCAACAATAATTACTTACAAAACATTTTTTGTTGGAACGTCTTTTTTTTCTGAAGTTTTCTTAGATTTTGATAACTTTCTTAATTTCAATTCAAATCGGCAAAATTGTACGCGTCTTTTGACTGTTCCCACATCTTTGTAACGAATACGGGAAAAAATATTTCAAAAAGGCACTTTTTTCAAGTGTTTTCGCCTTATAAAAGATTGCCTTCCGGCAAATTGGGATATCCTACATACGGCAAATCGGCGAACTGACAATTTGCCGGAATCGAAAGATTCCGGCAACCGACAACCTTCCGATTTGCCGGTGTCAGAAACTTGAAAAGTGTAGAAAAATAATTGGACGTCACAACTAAATAATAATTCATGTCATTTCTTAATGTATTTTAATACAGTTTTGACGTCATTTTTCTCCATTTTTCATTCTTCCGGCGCACTTGAATAACCCTGTATACCACTTAAAAATCATGTTTAATTTACAAATTTGTAAACTCCCGATTACCTGCATACCGGAGGAACCTTCCTAGTACGTGAATCCACAAATTTCCCCGGCGTCTTCATCACTATGTATGTCTTTTCACGGAAAAGTCGAACACTATCAGTGCATCGAACAGACGGCGGTCAGCGCAATTGACCTGTGACCAGGAAGAACATGGTACTTTTCCAATTTGACACAGTTGGTCTCGGTGAGTCATTTCGGGGCTGTAGAGACAGGAAAAGGGGGAGGAATGGGTGAACCGGTATTCGTTAGACTGAGACAGGTGAAGATAACAGTCATGATTTTATATTGTGAAGAGTTGTATTATAAAGGTTGGTTGACTAGATTTGATTATTTGGGCGAAAGAGAAAGTGAATGAGGGGAAAATTGTTAAAATTCGGATTTAAGTATGAAAACTCACAAAAATGTTATATAAATTTATATTTTGGATATAACTAATTAAAGATTTTATATAGCAAGACTTTAAATAATATGAATATAATAATCTAATATATCAATCTCCTCATTTAATGGCTAGTTGTAATGTCCAATTTTCCAGCACTTACCTACAAACGTGACGCGGACGGTCTCTGCCATCGCCTCGTGGTAACTGCGATTATTTGTGAAACAGCGACATTTTCATCAATCGGATCATCGTCATTTGGTTCATCGTCGACAGTTGATGTGGCATATCGTACATCAGTATTTCGACACGCGGGTTAGATATTTCATCGAACGATATATGTTGGTGACACAATTGCACGGAGACGCCAATGGAGATGTTCGATTGGGAACTTATAAGAATCGAAAAGTCGCGCTAAAAGTGTCGAAAATGCATGGAAATGGAATGTTGGACTCATTGCTGGATGAAGCCATATGGTGTAAGTTATCCAATTATTGAGAAGAAAATAATTTTGGCAAAGCCCAAAACAATGCGTGTTGAACAATGTCATGTTAAAAATATATTTATGTTTCAAAAATGTATTTCAATTTAGGTGTTGCTTTTAATTTGGATCTCAATAATAACAACGTTTTCCAAGTTTTTAGTTATGAGTACCCCGAAATCTGAAAAATATTTTCAGTTGACTTCCAAATTCCCTGATTCCGAAAGTCTAAGTGAAAGATTCGAAACCTGATGGGCTGAGCACAAATTATTTGTACAATTTAAACACTTTTTAATTAAGATAAATTCCCCAATTTTTTTGAAAATATTCCATTAATTCCTATTTTATGTTAATAATTGATTCAGTTTACAAAGCTTAGTTTCATAATTTTCAATTTTCCTGATTGATGAGATAACTAATGGCAGCAAATAAATCTGAAAAATCCCGAATTTTGCAGAGGTCTGTCGCTGAACATCCAAATCTAGGGACGCTTGTCGTTGTTGTACTGATGATGAGTGAATGTCGACATGATAACTGAATATATGGCAAATAGTTTTAATCGATTTACTCCGATCTCGAGGAAGGCATGCGTTGGAGAATCGGAGGCAGTTAATGTATGTTCGATGTAAGAAAAAGTTGACAAATAAAAAAATTGGAATTTCACATTCGCCAATTAGATTGTTCAAAAATTGTTGACATTTCTGCATTTTTATAACCGAAAAATCGACATTTCATTCCGCCTGAGTAATAGTAACTCACCACGAAAAGGGTTACTGTAGCAGTCTTTTAGCTGTCTCTGGTTTAGTAATTTACGATTTGCCGGTCGTCTGAAACCCGATTTTTTCTAGATTTTAACAATTTTCTAGTATGCTGTTGGCAATTCATTCCAAAAACATTTTAATGTTGCCGCTAAATTTTTGTGCTCCGTTTGTCGAAAAGCCGACTTTTTAAAAACACTGCAAAATTTCTCTCTAAGTTTTTTAAAAAATGGTTGCCCTTGAAATCAATGCAGTGTTTATATTTTATTTTGGATTTTTCGAACAAAAATTTTGTTCGTCTATCCGAAACACCAAAAAATCCACTTACCATTTTTCGAAGCGAATTTTTTTTTTCCAAACAACAAACCTGATTTCAAGGGTAGAAACATTTTTTAAAAAAGTTGAAAAAAATATTGTAAAATCGGTTTTAGTTTTTAAAAAAAGTCGTTTAAATTTGTTGCACAATTAAAAAAAAATTTAGAGAAAAATCTTGGAAGGCTTCACGCACACAGCTGAAAATGCTAATACAGTACAGCTTTTCGTGGTTGGACCCAGCCACCGTGGTTACTCTACCTCCGGCAAAGTGGAAAATTCGATTTTTTTGTTAGAAAATTTGAAAATGTCAAAGACCTGTGAAATGTTTCAATTTTTTGTGCCAGCTGTTCTTGAAATCCAAATTATTCGACTTTTTTTCCATTTTCAGGGATACTTGCCAAGGAATTTATCTGGAATCAAAACAGATTGTTCATCGAGTGGCCGCTCGAAATGTCCTCGACGATGATTTAGTAGCGTAAGTTTCCGTTTTTGGATTAGCGAAAAAAGCACTAACAGCCAGTCACATGATTCGGCTTCTGGCAAATTTCCGGACTGATTAAATGGACGGCACCTGAAGCGCTTAGACATAATGTAAGTTTGGTTGAAAAATTGATAAAATTGAGAAATTTTTACAGAATTTATTCTTTCAAAATTAACAATTTCATAAAAAGAAAGAAAATCATTTCAATTTAAGGAATTTCGTATTAAATTTCTAATTTAAAAAAATGTCGATATTTTTTAAAATTAACAAAATTTGAAAACAGAAATCCGTAATTCCGCCGAAAAATGCCTCAAAAATCTGCACTTTGAATTTTTGCCCAAATTTCTAGAATTTTTCCTTACTTCATTTTCTTTCATAGCTTGAATATCAAAAGGAAAATCTTGAAAAAAAATCCCAGAAAAATAAAAAACAACCAAAATCGATTGATTTCAAAAGTTTCTTTTTTAAAAATTGGTTTTTTGTCATTTTTTTCTGATAAATGGAATAGCTTGAAACTAGAATTTGAAAGTATCCAAATTTTCTAATAGATCGATGAAAAATGACTCAAAAACTCCAAAAAATATTGAATTTATCTCTTAAATTTTTCAAAAATGGAATTTTTTTCACGTAAAAAATAGAATTTTTTTTCCCAAATTTTTTTTAGCAACACCACAAAATCCGATGTTTGGTCATTCGGCATTCTTCTTTGGGAAAAATTTTTTCATTCGGACGAATACCGTACCCAAGAATTGTGAGTGACAACATTGCTTAATTAAAAAAATTTCTCGTGTTTTTTCATATTATTCCTCGCTAGCTGGATTGTTTTTATTTCTGTTTGGTTGGGATCATTTCTTTAAAGGCTCCACGGAAAGGGAATCTGCCTGCGAGAATGAGATCTACGAAAATGAGCGACAATGCTAGGATGAAACGTGCGTTGTTTAGCAAGTTTTTGATACTTTTCAAAAATACTAGACTTTTCAACCTTTTTCGTAGATCCTCTTCTCGTAGTTTTTGGTGGGTCCCCTTCCTATATTTTTGGCTTGGCCGAGTTTTCTCCCGGCCACGATCATCACTATTTTATTGATTTTTGTCATGATTTTCAGGGAGCCGATGGTCGATCGGTATGTGTATATTGCATATATTCGTTAGGTTCTATTTTTTACCAATTCTATCCAATTCTATTATACAATACATCTCACTATATTTTCCCCTGCCTGAAATTTTTGAAAAAAAATGAGGCAATTTTAACTTAAAGCTTTTTCCAAAATTTTCCAACAAAAAAAGTTTTTTATTTTTCAATCGCTCGAATTCTGAAAATGAAAAATGATGATAGAAATTGTTTTAAGAAAATGATTTTTTTGGTAGCAAAACGAATTTAATTTTTAATCGAAATACAACTTTTTTTTCAAAAACACCTTATTCGAGACAATAATATTTCTTTTCTTTTCAAAATTGAACATATTCTGGAAAATTGAATAATTAAAAGCATCAAGATTAAATATTCGAAAAAAAGAGAAGTATAGATTTATTGGCTTATTTGGAAAAAAGAAATGAAAAAAATGCAATAATCGAGTCTTTATTTTGGTTTTGTTTCCGACGATGTCCTTCTCGTATATAGTATTTTCCTACCACGAAAATCGCCGTGCAGGGTCTTTAAATTCGGCCGACCACGTCTCGCCTAAGTCCAGTCCCCCACATGTCAAATAAAATTTTTTTCGCAACATCCTGAATTTTGAAATCTTTTTCCAAAGAAAAAAAGTACCGTTTTTTATTTAATTTTAGAAGCTTGAGAAAATGCTTGGAAAAAAGTATTATTTTTTCTAATTTTGAACTTTTTAAAAAAATTATTATATCTTGATTTTCAAAATTTTCCATATTCGATGTTAAAAATTATAAACATTTTTCAGAAAGTAATACCGAAATTTTTTTAGAAAAAAGTCAAATTTGGAGCGAACATTATGTTTTTCAACAATTTGTCAACAATTTTTGTTCACCGCGATTTTTTTTTTGGATCCAAAAAAATCTTTGTTTGTGTGATTTCCGACGGCACCCAACTCCCCAGAATTTACCGCAAAAACTCTATTTTTTTCTCTGCTACCTCTTCCCTATCTTCTAATTAATGTTTTTTCACTATTCGTTTTTATTATTTTTTCCTTTCAGAGCTCAGTTAGAGCCCAAAACTAACCATCAGAAACAAAAAAAACAACTTTCTTTTCTTTTCGAATTAATTTTTTCAGCCTAGGTTCAAGGCGTTGTGAGATATTGAGTAGGTATCGAATGGAAGCACCTGAAGGGTACCGGAAATTTTCAAGGTTATGAATGAAACATGGGCTCTTTCGGCACAAGATCGACCGTACTTTAGGACAGGCAGATTTTTTAAGGGTTTTATAGAATTTTAAGAACGATTTCAAAATCCGAAAAAAAAACCTACAATTATGGTAATTTTTGAGAAAATCTACAATTTTTTTTCGAAAACCTGACAGAAAGAAGAAAGATAATTTGAAAAATGCCCTAAATTGACCAAAACTATGGAATTTTTACCAAAATTTCAGAGGGGTTTTTCAGATTTTACCAGAGTTTCTGCCTTATAAATTAAAAATTTCAAAGGGAAATATTTTTTTAAAATCAGCATTTTTAGCAATTTTTGTGATAATTGTTTATGCCAAAAATGGTGCGAATCTCATGTTTGAAGATTTAAAATTCAGAAAAATCTAAATTTTGGGCAATTTCAATAAAATGGAAAGATTCTGAAAATAATAAATTTTTCGAAATCATGAAAAAAATTTTACAATTTTTGCGAAAAGAATTGTGAAAATTAGAAATTTTATTATTAAAAATATTCTCATGATAAAAACAAAACATTTCAAAAATCCGCCGAAAATGGCTTAAAAATCTAAAGTAAGAAAAGATTTTGCATTAAATTTTATTGATTAGTATTTGCCAAAAAAACCCGAAAATTCACTCTAAAATTACAAAAATTTCAATTTTCTTAAGCTGCGTCCACAAAATGGCTTTAAAAATCATTTTCATGTACAATGTCAAAATTTTAAAACAAGTGAAATTTTGTTCAAAAGTTACCATAATAAAGGTTTTATGCTTTCCGGTCATTTTTTTTAATTTTGGCACACTAACCGAAAAAAAAATTGCTCCGCATTTTTACCCTGAAATATGCGAAAATGTTTGCATTTTTTGAAAATGCCACTTAAATTTTTTATATTTTCAGGTCGTGCCGATTGACAACCATCCGAAATTACAGTATGACATCGGCGCACATCTCGAAACGTTTTCCAGAATCCATATCCACCGAATTTTCTAGTCCATATGAGGTTTCTGTTTTTTTTTCGATGTTTTTTACACAAATTTAGTCATATTTTATAGTAATTTCTCCCACACATTTTTAGGCATCGTTATTATATATTTTCTAATCCGCTGCCACGCATTTCGGATAGAGATCCTGGAATTTAAAGGCACAGCGGTGTTTTTGGATGGGTCCCACCTCGATAAAATTTTTGCCATGCGCTCCTTTGAAATTTTGTTTTCGATATTCCTAAAAATCACAAAAAACATTGTTTTTTCTAAATTCGAGAAGTTTTAGCCTTTCTTTCGACTAAAAGTCGATTTTTTTACGTTGGTTTAAATTTTTCTCGATTTGAAAAAAATTTCAATTTTCAGTGAATCAAAGAAAAAACATCAGGGAGCAAAACTTCTATTCGAAAGAACAATATTTTAAAATTGTATTTTCCGATATAATTTTCACTGTTGGGTCTCACCACGAAAATCGACATGCACCTTTATATTTCCTTGCCAACACCTCTCCGAACGGCCGATACCAAATACCTACGGGTTCTTCAATTTTCCTCTGCATCATCGATGCCGTTTTTAAAAATTTTTATCGAATATATTTTCACGTTTAAAATTATTAATTTGTAACGCCAATTTCAAGAAAAAAGGCTCAAAACTCCGCCATTGGGATAATTTTTGCAGCGACGGAAAATGCAATAAATTTTATATTAGTTTTCACCGATTTTTAACAGACTATTTTTAGAACTTTTAGTCATTTTGTATGTGTGTGTTGCTAGCGTTTATCGGCAAGAAATTATTGTTTTTTCTTAATTTTTAATAAGGGACATTTTTTAAAGAGATTTTCAGAAAATCGGTAAAGATTTAAGATGCTCTGAATATGTCCAACTTCACAAGCTTCGTAGATTACGCGGATAAGGTGTTGAATGAGTTGAATGTGCAAGTGCGCCCTATGGATAAATGGAGCAGCGTGGCAATTCGAAAATTCAAGAAATTTAAATAAAAACGTATTACTCGAAAGTTCACAGAGTTTTTCACCAAAAAATTGAAAATTCGCTGAAAAAGTCGCGGGACATTTTGATTTTTCGGGAAGATTAGAATTGACTGAAAAAACCGCGTCTTTATTCGAGAAATTTTAGAAAGGCGGAAAATTCCAGATTTCTTTATTTAAAAAAAAACATGAATAAAAAATTCTGAGAAATCATGAAAATTGATTGAAAAGTTTCAATTTTAGGCTAAAATTTTTTTGCGAAAAATTCATTTAGTTTATGTTGGTAAAGTTCCGATTTTTCTGCAAGACGAATTTGAATTTCTTTCTGAACAAGTGCGTTTTTTTTCAAAAGTTTTTAAAATCGGAAATTTTTCGCCTCGAAACTGAACCGAAAAATTCGAAAAATGAAGCGCGGGCAATTCGTCTTGAATTTTGGCATTGAAAATATATGAAAAATTCAAAAATTGGAAAAGCTCAAAGTTTTTCACAAAATAGTCGATGTATTTTCTCATTTTTCAATGTAAAAACCGATAGTTACCGCCGCACGCTGGGTCGCAGCAACAATGCAGCCAGACAACAATACCGCCGTCACCGTTGAACGTAATAAAAAACGGCCAATTCCACTGTTAAATCCAAGTGAGTTTAATCGATTTTTCTGTAGAAAAATCTGAATGTAAATTTTGAGCTGAATTTTCAGACGAAATCAGCAGCTCTTCGTGCTATGACGTCTTTCCATGCAATCCGGAGAATCTCAGCAGGGACATGTTATGTACAAGAGTTCGTCGATTCTATCCTGCCGTTGCTGAAAGAGGAAACTCAAAATGAAAAAAGAACTATAGTACTATACATTCGAAAAAAAATTTTCAGTTTACAGGCGCATCTTTAAATATGCATTATTATTCATTAGTGTCGACCCAGAAAGCGCATGCAAATTTTGAACTAAACTGGAATAAAAATTTTATTACACATTCGTGTAAGAATATTCAGTTTAAAGGCGCGTGCTAGTTTTAAGCGTACTTCAAAAATCAAAAAAATATATATATCTATTCGTGAAAACATGTTCTTTTTAGAAGCTCTTTAAAAGTTTAAAAATGATTATTATACGGTTTCTAAAAATTTCCAAAAATCAGGTCAAATGCACTTAGAAGATTGGAAAATATGAAATCTTTATACATGCCTGAAAAAATACGGCATGGTCCAAAAGTCGACAAATCGGTCCAATATTTTCTATTTTTTCAGAGAAATCTTGCGCCAAGGTCGAAATTTTTCGACGATTTCTACGACGTTCCGTGCGATCGCCAGAATTGAGGAGGGAGACCATTGTGAAAGTTGAAAGCAAATATTTCTTCAAAAAATTATTATATTAAATTTACACATACACATTCGTGAAAAGATTTAGTGCTGCCGGCAGGTGAAAATAATGAGATGAAAAATATATACAGAAAAAGGAAAATTTGAAAAATATTTTTTGGCGATAATTAGAATATTACCCGCAAACAAAATTCAAATGACATTTCTTCAGTTTTTGAAAATCTAAACACAATTTCAAAATGTCATTATTGGTGATTCGTGAAAAAACTCAGTTTAAAGGCTCATTTCATATTCAATATAAATGAGAATTATTAAACATCTTAAAGACATAAAGTTTACAATATAAATGAAATCTAAGAAGAAAAATTATACATTAAAGTTGGGAACAAAATTTTGTATTTGAGTAGGACGCTTGACATCAATTTAGTGATATAAAATTTTGAAACCAAGAATTTTCGAAAAAAAATCACGTATACCTAAAAATTTGTAGTTGTTTTTTTAAAGTTAGTACAGAAACTATTTTCTCTAAAATTCAAAAATATTCCAGGTAACATTGGAACACAGGACAATTTTCAACCCTCGAGACAAGCCTATCAATCCAATGGAAACACTATCAATAATTCCGAATATTAAAAGATGTCAGAGTTGTTACAATTGACTTGAGAAGATCTCAAAATGAATATATTGGCCAATCAAATACTCTACCTCTCGAAAAGGGGACCAATCGAAAAGATACTCAAGTTGGACCTGCTATGGAGGACCGCGATGTGAAGGCGAAAAACCGTAGGCATTGGATAGCTAATTAGTATTGGGGGTTGGGAGGGGAGGGAGGAAAGTTCGAGAAAATCGGAATATCTTATGCACTAAATATTACTTAGGCCGTTTGATTAATAAATCGACACATCAAGTAAATAAATTCTGAAACAAATTAAAAAAACGTTTCGATTGATATATGTGTATCATTTTCAAAAGATGACATAAATTGGCAAACAAGAAATTTTTTATTCAATAAAAATATACTACGGGAGCCTAAACTTTTGGAGAGTGCGTATTGCACAACATATTGGACCAGATATCTCGAAGCGAAAACTACAGTAATTCCATTTAAATGACTGGTGTCGATTTACGGGCTCTTTTTTCATTTCTCCGGATTATTTTCTCTTTTTTGCTAAATTTTAATATTCTATCTATAACTAAAAAATTAATTCATTTCGAAAATCTAGCCCGAAAATGGACACAAGCGCTACAGTAGTCATTTAAAGGATTACTGTAATTTCGCTACGCGATACTTTGTGCGTCAATATATATTGTGCATCCAGTTACGCATTTTCAGAATTTTGTATTCTCATAAAATTTTCGAAAAAGTAAATCTTTTAAAAAACTTTTTATTAAATGAATAAAAATTTTTCCCCTTGGAGAATCGGATAAAAATAATTTATTTAAGTTTTGAAATTTTAATATTTTGAAAAAGAAACATTTGACGTATTGAAGAAAAAGATGAACCTTCTTTTGTAAATATGGTTTTTACAAAATTCCAATCGTCCAATATACAGACTCATCATTTTCCAGCAGCATTTAATAGCTACGAAGCATGGCGCGTTCGGAACTCGAAAGGTGCCAGCAGAAGACGGATTCGACGTCTGTCTGGACAATTGCGTAGCACTTAACAAAGAAGGCTTCAACTATGCGGCTCAGCGGGGTGCGATTTTTGGAAAGTCAAAAAACTGGATTTCCGATTAAAAATATGTATAGTGTATGTATTTTTCAAATTTCCAGCTACCCTGTGTTACGTAGTAGTGAGCAACTTCTTGGATCGTGTGGACATTGAACGACAACTACAACACCACAAACAGGGACGATTTCCGATTTGGGTGTGGTCTCGGGCGAACGGACACTCGACGTTATTCGTTTCGGCGCATCACGAGAACTATATCGGATGCCGGGGATTTCGGCGAAGTTAGTACATTATATTTTAAGTATGATTTAAAATGTTATTTTCTTACCCAGCAGCGTTTGCAAGAAAGTATCACCCGTTGCCATCTGAATAAAGAGAAGCCGCATGTTCTAAACTTGGACGTCGATTTTGTGTCGAATGTTGGAAAAGCTTTTGATAATCTCCCATAGCTTAGTGCAATTGGTGAGGGAGAGCATTTCATATTTCAAAAAAAAGTTATTCGCCGTATTTTCAGCTCTTTTATTTTCCATAATTTTACATATACTATGCAATTTCCCAGACTCCTACGAGCAATACGTTACACACAGGTGCAAAACGGTTGGAATACGAAACTCCTATCGGGAGAACCGGATCGGGCTACATCTCGTCAACCTCTGCAGGATCACAACCTATCAGACGATTCAATGGATAGTTGATAGAGATCGATCGGTTAACAGGGTGTACTATCAATTTAGTATTCAGAGAGAGGGAGAGAGCGATTTTCATAAATATTTACATACGAGTTAGTCATTTACCACAATCGACTGATCAGAATCTGATACGTGGCCGTTTTGAGACCCTCCGCCAGTACTTTAGGAACTTGCACCGAACTTGCTGCTTGATCCTCCCCCTCCAGAGGATCTTCTCCAGATGGGATACAACTTTTGATGAAGCTGATCATCGGATCCTCCTGTCATCCGAACTAGATTCAACTGTCTGAGAAGAATACAACCAGTGTCTGCAATCACCGGGTTCCCTTTTGCTCGTCGAGTACTCAAATTGTGTCGGCATATGAATTTGTCCAACGTGGGAAGCCTGAATGATAAAGGGGGACTAGCGTCGAATAGTTATTTTTTATGTTTTTCATATACTCGTTTGCATTAAAGTAACGGCTCTCCTACCTTGAAATCCGAGTTCGGACTGATCTTTTCTCCGTTTCACCGAGATGATTCTTCTGGTGACTCGTTATTTCTCCTTACGCTGATCGTGAACCCATTTAATCAATTCCTGATCAACGTCGTAATACTTTAAAGGTCTTCCACCTCGACCTGTCGAAAGTCGCTTTGTTGCAGTTGAGCCTTTATCTTTCTGAAATTATTTGCCAAAAGGCACAAGTCGAAAATTTTTGGTAACAAAATGAAAATTTGAAATCGAACAGAGAATGTATCTGGGTTATGCCCAGTATTTCAAAATATAGGAATAGTAGAAATGACTTCTTTTGATAGGATAAATTATAAGCCTAGAAAAAATCATAGTATTTGAATTAAAAGGTCCACAAAAGGTTCTATTGATTCGGCAGGGCTTGCATGTAGTAGCGAAACCTGCCTTTAAGGCGACCGCCGCTTGCCTCTCGGTTACGCCTTACGTTGTGCTAAAACATAATTCAATCTTTTTTTTTTTAATTTCTATTCTGATTTTCAACAAATTGAGAGAAATGAGAAAATTAGAAATTTGTAAATTCACATAGGCGGGTTTCAAGCAGGACCCTGTCACCGCGCATGCCTAACATGACAGTCATAGCCCTGGACTCTTTCCTTTTTGAACACGAAAATATGTCCGAAGTGGCAAAACTTACAACTGCTTATGCCTCGATTTCAGCTTTGTGGGCAATGATCCATTGTTGAATGTTTTGACCTATTCACATTCAAATCCTTTGCTGCTTCGATAAATTCTTATGTTCGTTCAAGGGCATAATTTATGGCCTGCTCAAAATTCAAGTCATACGTTCTTTTTCGAGTTTTTACATGCACTGCTGTAGGGATTTCGCTAATTGGTTTTCTCTGAAAAATAAGTATAACAAGCAAAGTCTTAACTAGTCAGCAAGTTATTGGAAATAACGAGAGAGAAGCTAACGAAGGGAAGACCAATGGAGACAGCAAATTGGCTGTTACACACACAGAGAGACATGGCTAATAGAGTGTGCCTATTAGAGGGTCGAGGAATTGCAGTGAGACGAATTTACTGGGCATGAATGTAAAGGGGGTGCAAGGCTAATAGGAGGAGAAAAGTACAACTACAAAAGCATTATTATATAAAAAGCTAGGAATACCTGTATGGGCACCCCAAGATTTGTATGTAAGTAGTTATGTAAATGACTTTTTGGAATTGAAAGGAAAATACCAAAAATGGAAAAAACCTCCGGTCAATCATAAAAAAATTTTGAAAGAAGTTCGATCTAGGCTACGGTTTACAGTTTCCCTGATTTCTACTAAAATGCATTAATCTTGAGTTTATCTCTAACAAAGTGATGGTACTTTTGAATGGTTATAACACAGGTTGCAGAAGACGAAGGATCAGCTATGTCGATTATTGTGGCCCTCAGAGCCTCACGCAAATGTGGTGTGCTCCAAATTTTACAGAACAACTACGAGTGCAAAGAGTTTATTAGAAATGTTTTTTCTGTACTAAAAATGGGGTTTAAAAAACGAATTTTGGTTGATTTAGTTCTCTCCTTGTATAAATTTCGAAAATTTTCCGAAATTTTTTTTTCAATATAAACAATGTCTTCAACAACTCATCGAAAAAATGTGGATTTCGCGCCCTTGGCCACCCATTTGGTGAACGGCTACTCAGAAGAACCGACGATATCCATCGAGACGTGGGAAACCACAGAATAGAATGAGAACTGACGTCATGCCGATGTGGTTGATCTTATTGGATTGTGTTTCACAGATAAATATATACATTTGAGTAGGTTTGGTGAAAAAAATGTTTTTCCTCGCAAAAAAATGTTTTCAAAATTTGAATTTCCCACCCAAAATTTTTCTCAAAAATTTTTTTAAAAATTAATTTTAAAATTATCTGTTTTCTCAAAAAATTTGAATCTCCCGGATTTAAAACTTCCAAAAATTCGTCTATCAATAAATGTTATATTAGATAGTTTTCGACGAATCATAAAAATTAGTTTCTAACGCACTTTTCAAATAATTTTTTTAAAAAATAATTTTAAAAACAATTAATTTTCTTCATTCAATTTCCAGATTCACATTCTCTCCACAAAACCGTTCTCATTGCACTATGGGATCTATAATTAACTGGAATGGTCCCATCAATGGCTTGTAATAATCTGGAACAGCAATTACTCGCAAAAGTCGGCGGTGGACCATTCCCATTGGATCGATATTTTGAGAAAAGATACCTACTCGAAATGGAAATATTTGGCACGACGCAGTGCTTTTTATGGAATCAATTACGAAAAGTTGGTGCTTTTCAAGAAAAAAATCCATTTATATCGATTGTTTTTTTCTTATTGATTTCAGCTACTTTTTCACCTCCGTCAGCAATATTTTGTTGCAACATTTTGGACGTGGCCGCGAAAAAAAAATTGGTGGCCGAGTTGTCTTTTTTTTCACTGCCATTAATTGAGAGGAAAATCTCAGGAATTGAAAATTTTTTCGAAAGTATACAATGTTGACCGAGAAAATATAGGGGGCCGTGGAATTTCTCTTTCTTCTCTGCCACGTTATTTTAGTAAACAATTAGAATAAAAAACACAGAATGTTGTTCAAATTGAAAAAGTCTCTAAAACAAGAAAAAATTGATGGCCGAGTTTTATTTCCATTTTGCGCGGCCACGTGACAAGCAGTGATTTCTCAAACGTTTTCAGGAAAAAAAAACAGGCGGAATTCAGATAATCCTACGAAAACTATTTGTTTCTGGATACAAAAGTCAAAACTTCAAAATCGGTGGTCGAGTGTTCTCTTTTTTTGCGGCCTTATCACGATCCAGAACCAGTGTGTGCTCACTCGAAATTCCTTCAATGTGAATTTATTCGGCCAACGTCGAGACGTTTTTGCGATATTCAACTGTGGTCCGCGTCATCGATGGATTCCTCCGGCAAACGGGAAAAATTCGGGAAAACTCGGCGAAGTAGAACTCTCGCTGGACGAGAAAATGATCGAAATGCCCTTGGAAAAAATGGAACTGTTCCGAGTGGAAAATGTATCATTTGGACCTACCGGAAGAGGTGACCAAACTTTTGGATTTATAGGCTTTCGAAACATATCTTACTCTCAATTCTTAAATCTTTAGTATTCATCTTCATATCCTTAGTCGATTCCGGAGATTTCCCCAATAATTTAAATGATTTTGATATGATCCGGCCGGATGATTTCGGCGCAATGTCCATGAATTCCTCCATCAACTAACTCACCATCGTTCGTTAATACGGTAGGGATACTTATTAGCTCGGAAAATAAATAACGACACATTTTGTCTCGAATTTATTATAGGTGACTTAGTAATAGACATTTAGTGTCTAGGCACGCATAAAAATTAGATCTTTTTCATCGTTCCGATACTTTCACACAAAAGTACGTTTTTTTTCGCAACGTTGTCAATTGAACAATCAATAGGTCGGCAAATAATTGTTGGAGTGTTTTGTCACACGATATTTATCAAATTTATATGTGACTCCTGGTAGAAATTTGTTATGGTCGGCAATAAGTACTGAGTCATAAATTCATATAACTTGTTGTTTGCTTATCGATTGTTTTTAATTGCCGGAGTTCATGTTATTCACTATGGGCTTTCATCTTAGTCAACATTTGGTTAAAAACTCGAATCCAAGTAGAAACAACTTTTTCAAGGTTTACGCCGTGCTTCTTTTTTCTCTTATTTTCTGCACTACATTGATATTTATGTAGGGATCCAGGCCGAGTGTCGGTATTTCGATTTTTGTATAAAATCGAAATTTTTTTTTTGATTTTTCGATTTTCCCTGAAAACACACAATTGAAAAATGTCACCCTTGGTACGGATATTGCTATCTATTATACAGTGTGAGAATCCAATAAAATTATATTTTATTTTTGCAGCCAGTTCGTTACAACACGACAACAGATTGAAATCAATATTCGATCATTCGACACTTGAGAAACGAAATCGTCGAGCAGCTGCCAGAATTGGCCCCCGCCAGTTATTCAAACCAAATGGCAAATTGTCGGATATTCGAAATATGCTGATGATTCACACCAAGACCACATTCCCGAACTGTTGAGACGCCTATTTTAAAGACTGTACGGGATTTTTGGAAAATTTAAAATTTGGAAAATGAAATATTCAAACAAAACAATTTTTTCGCTTCATCAAATTTCATAAAAATTTATGTTAATAAATAGTTTTTTATTGAATTTTAAAATTCTTACTCAAAACTTTCAAAATAATTAAAAAAAAAAACCAAACTTGTATATTTTTTTTTATTAAAAAAGTTAAAAAAAATTTTTTTTGATAATGGGTTGACACTGCGCCTTCAAAATTTGATGAAAATCTTAATACTAGATTTTTTTAATTTTTCATTTAAGACTTTTCGAAAAATTCGAAAGTTCAAAAAAAAAAATTCAAAAAAAATTTCACTCTAATCAATCCCCCGTCTGCAAAATTTTCGATAAAACGATGAAAATTTTGTGGAATAAAAATGTTTAATTTATCATTCTGAGGCACCACGATTTAGTCAAGATCTGGCTCCTGGGATTAAGGACCCGATCTTGAGTACATGATTCTTCATTTCCAGCGCAAAATCCTTAAATCCGGGATTCCACCGAATCCGGCTTGACACCCGAGGTGCCTCATCATTCTACCTTTAAAAACTCCAAATTATAAAAAATTCTGCAAAACTCTAAAGAAATTTGATTTTCGATTTTCAAAAATTTAATTTTTTGTATTAAACATTCAAGTATAAAATATTGATGAAATTCTAGAATCATATTTTTAAGTTTTACAACATTTTTTAAAAATCTACAATCGTTCACTTTCTTGCCTTCGAAATTTGAATGTGAAGAAAAAATTTCAAATTAGAAATAAATTAAAAATGTGCTCATAGAATTCTTTAAAAATATGCGTTTCCCTAATAATTTCCATGTTTCAGTCCCCATCGCCCTCCTACACCCCATTTAACCCGACGCCCGTTCACCGGAACCGCGTCCGTGCCGACAATCGCCCAATTCGCCCGGCGGCCGCAGGGGCTCCTAAGAAAACTGACCCCCATCAGGCCCCGAGATAAGAGCTTATGGAGATGTGGCTATAGAGAGCCCTACTACTCGGGTCCCAGATTTTGAAGAAAAAGTTATACTAAGGTATTCGAGTTTAATTTCCGCTCTGGGAACACTATTATCTATAAACGTATGACCCCTTTAAATTGAGCTCCAGTAGTCAAAAACGTCGAAAATTTTCAATTTTTTTGAATTTTTACTTGAATTTTTTCATCCAGTTCTAAAAAAAAGCTTTCAGCTCTACCCCTTCTTTCATTTGTCACCTACTGCCTCGCTTCATTGCCCTGGGGTTAATTAATTTTTTGATGCTTTTCTAGTCCCGCCACGGTTTTTTTCATTTCGGAAAGTCTCGGATCGATTATCAATTTTTTCGAAAATTTGGTAAATTTAGAGAAACTCTAAATATTATCGATTTTAAGATACAAATGATTCTAAGATTTTTTTTTTCAAATAAAATTTTGGAAATGTTTTTTTGTAAAAAAAAGTGCAAAAAACACTTAATGGAGAATTTTTAAAAAATTGGAAAAAATCTTGAAAGTTTGTCGATTTTTCAGAGTGCCTTTTGGAGTTACGTGTCGGTTTTCTTTCCGAATTTTCATCAAATTTACTTTCTACCAAAAAATCTCTAAAACGCCGTGGCGGGAACCTACTTCATTTTTATTCTGCATAATTAGACAAATATTATTTTCTCATTTCAAAACTTGTTACATATTTTGTGTTGTGAAACATATGTCTAAATTTTTACGGACTGAAAAAATATTCTTAATGTTTTTGAAATTTTCATTATTGGCGTCATCCATGTCTATTTGATTGTTTCCACACCCCCCCCCCCCCCTCAACGTAAAATGAAAAGAACAAGACGATTGACAGCTAGCATGTGCGACGATCAAAGTACCGATTTGATTCAGTTGAGAGGGAGGGACACGAGAACGCGAAAAAGTAGTCGGAAGCCCATCTAAAAGTGCTGGAATACATTGGCAATCGCTATGAAATTCGAATGACCGACGGGAGAGTCTGTCCATACGTGGCACGATGATCGCCACTGTCAAGGCTAATATGGTTTTGAACAAGGTAAAAATTTGATGAAAATTTGGTTTGCCAAAAGCTTCATAGTTTCAAATATTTTTCCTTAGGAAAAATTATGCGCCGCAGGCACGATACACTAAACTTTCCGCTTTTTTCTATTGCTGGCTTAGTTTTCGCAATTTTCTGGCTACCAGTTCTGCAAAAATGATCGATCCGTGAATTGTGCAAACATCTGAGTTACACAGAGAGTGGGGGCGGGGCGGAACATCGCAACACTGCCGGACCCATGGTTTTGTCCACAACTTTTTTTTTCAAGACAAAGTCTCGGACGATTGTACTTGCTTTTTCTCTTTTTTGTATAACAATGGTATTTATACTAAATAATTCACATATGGTAAATTGCATATAGCAAAAATGGCACAAATATCCTCTCAAATTAAGGGGAGCCTTAATCTTAATTAAATTGGATATCATTTTCATTCGAAAAGAAGAGAGAAAGAAGTAAAATCGAAACTTTTGCTTTTGAAAAAAATGCTTGATTTTATGTCATTTCCGTTGTTTTTTTTTCAGTATTTAACTTTTGAAAGATTTATTTATAAGGTTTGCGGTTAAAAACGCTGAATTTCGCGTTTTTCTTTTCTGGATTCAAATTACAAGTTTGTTAGTAACAAATTCGAATGTCAAACACGGAAAAATAAGCGAAAATAACAAAAAATCCTGTATTGTAACCACAAAGTTCTCCACGAGTGGTACGACTACCGTGGAGCCGACGCGCCGCAGGTTTGCAAAACAACGCCCACCCCGTATTCTGCGCGGCACTACACAATTTTCTATCTCACGAATAAATTTTTCAGAAAAGGCAGGCTTTGGTCTGTCGAAAATATCATGAAAAATCAAGTCTTTGTCAGGTTTCCAACGCTGGAAAAGGTAGGAATTAGGGTTTGTTACCAAAAATCGTATAATATTAAAATCCCAGTGCTTCTCTGTCTTTCAGCAATATCTTTTAATTTCCAGGCAGACGAGCGATGGGACAAAGATCTTGAAAGGCGTCTGATTTCTAGGGCAAGCGATATCTCGAAAAAGCACCGCGTGGATTCGATGCACGCGTTGCCGGACCCTAAAAACTGAAATTATCCAGTTTTCTTATTTTCTCTAATTAATCCGATCCTTTTCTTGACAAGATTAATATAAAGTAATTTTTATCGAAGCGATTTTTGCTCATCTCATCCAAATATGAAAGAACATTCGAAGAAAAATCGCCGGCTTCACTTGGAACCGCGGCCATCAGTTGAGAATGCTGAATATGTACAAAGACTGGAAAATATTAAATTTTTCTGTTTCAAATTTCACGTTTTTCGCGTTTTCCACAAAAAAGCAAAGCATTGTAGTATTTCAAAAAACACTCATGGTAAACGAAGGCACCGTGGAATACACGATAGCAATGTGAGACCGCATCGACCAAACTGGGAAACGCCTGCGCCTTTAATTATGTTTAATTTTCGAATTTCGAGTTTATTTTTTTCTCAAGACTTTTGCGACTTTTTTAATATTTTATTACTTGTAGCGCTGAAATATCACAGTTATTATAGCGTCCCACATTGGGGACATCAATCAAAACAGGTATTTTTCAAAATATCGCCGAAATCAATAACCAGTTTTGAGATGTTGCCACCCGAGCCCCAGGCACGGATAATACTGAGAGAAGTTCCGGTCCAGAATACCCAGAAAGAGCAACCACCGGGTTCAGGAGATCAAAACCGTGTCCCGCAAGTCGAAGGACCATCGGACGTCAGTTCGAGCCGGAAAATTCCGGATCACTTCGACGTGGGCCGCATCACGGTTCCACATGAATGCCCCCGCAGATGGCTCAGAAGTCAATAGTTCGAGGACGACGAAAAAGACGAGTCGAGAACGAGTGTTGGGCGGTGATCGAAAGAATAGGAAGCGAGGATGACAAGTTCGAGGCCTCTGAGCTTGTTCCACGAGTGTCGAGTACCGCGATCACGATTGGTATATCGCGTTGGATAAATAAGGAGAAAGCCGGGGCGAATTATCAAGATTACGAAAAAAATTTTGATTTTCAATCTCATTTTTTAAATTTCAGCACCTACTCTACGGCTATCGAGGCGGAATCCAACGCATAATTCTCTCGCATCAACAGACGGATTCGATGGACAAAGTATAACGATTCGCCGCTAGTGAAGTACTGAAAATCATCGGAGACGGTCTGTACGTAGTGGTTCCGACTCGTTCCTCATACTGGTCTAATCAGTCCCAAATATCGTTACAACAAAGGCGTCGAGCTTCGGATTTTCGTTATAGTGAATTGGATTGATTCCGAATTGTGTTGGACGATCATCAGACGCCCAACGATCGTTTGGACAGATGTCGGACCTATCTGTCTGAGTGCCGCGAGCCAATATTCGACGGAAGCTGCTGCTGACCAAGATGCAAATTTTCGCGTCGTACTCCGAATGTGCCATATTACTGTCAACGGAATTTAAGCACCTTGGTTAAAAAAAACGCGTATAAAGAATAATAGTTCCAAATTTTCAGCTCGATTCCCGATGGTTCCCCGATTCCATGGACCATTATCATCGTTCCAGCCACTCATCGAACAATCAGAGAAGGATCCGATTACTGGGCTCAAATTATGGCCAGCGTTAGAGTGCTCTCGATGATTTAGTCGTTACAAAGAAGGTGCTTAATCATTTTAATATTAAATTTTACAGCATGTATAATTATTCATCTATCAGAAACGGCTCCCGCCTGTCTCAAAGATTGGAGGGTCACGTTAATGTGATTCGCCGGTGCAAATCAAATTCGGAATCATTGAGTCGGCGGGTGAAAAATACGCGACGCAGGGAAGCATGATGGCGGTCGTGGTTCAGTGCTATCAGAACAGCACGTTTGCATCTTTCGAAGCACTTATCGCCGGACCCCCGCGAGTCGTTGATTATTACCGAAGGACGCTTTCTGGAATTATTGCCCGAAGACGTGGCGTCTCGGAAAATGCGTGATCAGTATCAGAAAGAGCACGTTGTAAGCACGATTTTCCAGAGAAAAAGGCTTTCGATAAATTTTCTTATTTTCAGATCCGAAGTCGGAAGTTTACCAATCTGCATGAACACAGCCGGATTATTGTCTTGCCTCAAATCACTACGAGGATTCAGCGAGTGCCTTTGATCACAGGTTTATATATTTCTGTATTTCTTCTTCACTGCCTTATTTTAAAAGAATTTTCCCGTTTTTTTTCTTTTGTTCATTTTCCCCTTTTCTTGGTACGCTGTCGTTATGTCCCCGGTACATGCTAAATTAACGTATATTTTTAATTAGCAATTAAAAAACTTCCTGATTAACTGCCCGTTTTTGGAGGAGAACCAGAAGAACGCAGACGAGTTTCTGAAACTGAAAGGGTTTGAAATTTTTACCAATCAAACAAACTCGCAGTTCAAAAACCATGCCGTCGTTGCTCAAGTTTGAAAAAACCACTAAACATATTTGCAACGTAGATTGATAGAATATCATTGGATCTTATGGATCCGCAATGGCCAGATCATATTGACATTTACCGTTTAATGGGTCGGTACCGCTGAAAAGTTGCTGGTCTCGCAGCGAACTACAGTAATCGGGAAAAAGCGCTGTTTATTATCGAGTTTTCACTTACTCAAAAAAGTCAATAAACTCGCCGCGAGATCCAAACCTCAACTTACGATAGCTATTTGTAGGAGTCGATTTTCCATCGACAAGGAAGCCAGCGACTAGGAAAATTTTGATAGGGAGAAGCATTGAAATTTAATTGTTTTGGGGCGTTGCGTCTGGGCCGTTTTTATAGGAATTTTTGAGCTGTAAGAAAACAACGCAACATTTATTGCCATCAATTAATACTCCGGAAAAATATGAGTCATTATGGGGGGTTTTCAACCGTACGGATTTTGACAAATTTGAAACTACCATATAATGGTTAGTTTTGTAGTTAGAGAACTCAAAATTGATTTTCTAAGACAAAAACATTGCTTCAGAAAATAGTAGGTTTGTATAATTTCCAAAAAATTATTTCTTGCCCAAAAAAAAAAGAGCTTCATTAGATGGCTGAACCAAAAAATTGGGCAAAAATAAAAAGTGTCTAATTTTGGGGTTTGAAAACGGGTAATTAATATATGCAGAATTCAGAAAATCTAGGTTTAACCCATCAAAAACCATTAAAAAGGGGGACAAAATTTGGCAATTTTTTCAACAACTCACAATTTTGAAACCTCCTCTAAATTGGTTCAATTTGTAGCTACAGAACTTAAAATTGGTCTCCAAGCCATCAACAATTGTCCTTTTTCAAAATATAATAGTTTTAAACGTTTCTTTGAAAATTTATTTTTCTTGCCCACAAAAAAGGACAGTCATTAGATTGTGGCAAAAAATTGGGCAAAAATAAAAACTTGTCTAATTTTGTTGAAAACGGGTAACTCATATATGCAGAATTCAGAAAATCTATTTAACACAGCAAAAACCATTAAAAATCTAAAATGATTAATTTTCTAGTTAAAGCATGCAAAATGGATCTGCGGGAATACCAAAAAGTTGTCAAGTATCGCAAAAAAAGTGGTTCAATTAAAAAAAAATTAGTCTGGGGTTAAAAATCGATTTTTTCGCCGCACTTCGCAACTTGGACGAATTATTCTTTCGCTGCACAAAGTGAGAATCAATAATTATTGATTTTATTTCTAAAACAGAAAAATAGATATTCACTTATCTGAAAAATCGATATTAAACGGAAATTCGCAAAAATCGATGGTCATTAGTTTTTTTGCAAACCAGTAAAATCGCTTTTATCCTTCGCCGCATTTCCTAACTTTTTCTATGCCACTTGACCTTTTTTCTTCCAGAAATCTTGGAGCTTCCCAAACCCACTCATCAGCCAGCGTGCTTCATCAATCATTCCGTTGAGAACTATGAATTTATCGAGTGAAAATTAAAAAGAGGGGGATTTATTACACTGAAAAAGTGTTTTTGTGCCACGTGGCGGCCTGCAGGCCGAACCTAATTCCTAGCGGGAATTTCTAGGCCATGTACTTGGGGGAGATGGGGAGATGATCGAGGGGTCAACTTCAGGGAAAATGTTTGTAACAAAATAGAAAAAAAACTATAAAAGGTAAGAGGAGATCAAAGGTCACGCAACTAGGGCTTGAAAAATGAATGCCTGCCTACAAATAGACATGTAGGAATGTAGGCAGGCAGACAAAAAGTGGGTGAACAACGAGAAAAGGCACGTAAAATGGGGTAAAGGTTAGAGAAAAAGAAAAAAAAAGCTCACAGAGCACATTAAAAATGGAAAAAAACGAGATCATTGGATATTCTGCTGCAGTTGATCGTCATCATGAGTGGTCTGCTGATTGGGGTCGACTATCACATCATCTGGTTCACGAGAGCATCTTCTTCGAGCAGCTCATGGATGATCGTCTTGATGATTTGGCTGTTCAACCACTTGCGAATTCGAGGACATCATTTACAAATTAGAAAATACCATTTTTTAGACAAGAAATCGATAAATTTCTGTGTTTATTACTATTTTTCGGATAATTCCACACAATTAGATAGTTATTGAGTTGTCTTTCTATAATTTTCAAAAAAAAAAATTGAACGATAATTATTGATTTTTTTTTAAATCAAAAACTTCACAAACTCAAGAATTATATATTTTTCGTCCTCCTTCTCTTTCGGTTTTGTGTTTGTGTAATGAGTTTTTTTGAAAAACGCAAAATTTTCTGTGATATTTCTATTTTTTAACCTGAGGCATAGTTTTTGAAAAAATTTTGCAATATTTTCAGTGTTCTTTCTCAGAAAAACTCGAATAATTGCAAAAAATGTAAAATTTATCAAAAACTCATTTTCAGTCCTTTGCTCAGAGAAGACTGGAAAAAAAATTTCAATTTTTTTGAAAACCTGCCAAAAAACGAAGTTTCACTCGCGAAACATTTTTTTTATCTTTTTTCGAAAATTTAATACATTTTTTTGCAATTTTTTAATATCAATCCGTTCTCACATTTTTTGGTAAAAATATGAGGAAAATGCATACATTTTGGATTTTTTCAGAATATCTGTTTACCATTATTCTGCTTCTCCACAGTAAATACTTTAGGTGCTCCTTCTCGTGCACTTCTACTTCCAAATTAACATCGTCACCAACTGTCCCAATAACATCTTCCTCGACAATTTCCTCAACAATTGCTCCATCAGGAGCCATATGCAAATGCATTTCTCGATTATCCATTTCTTCTCCAGCCATTATTTCGTTAAACTCCAAACGTGTGATTCACTATTTGCAAGAGACGATGTTCGCTTTTTTCGAAGAGCATTTTGAAGAGCAAATCGAATGTCTCGTTGTCGGTTGCTGAGCCAAATGAGTTCTTTGCAATACGGAAGTGAGCCTCGGCTGTTTCGACTTGTTCAACGCGCCATTCCAGATGGTGATAGAGGCTGGAACTATTACTCAGAAATTTCAGATTTTGTTTCGTAACCAAATGTGGGAGCTGGGAAATTCGCGTTTTCGACGAAAAAATAGCCTTTCAAAAGATTATTTTCAGATATGTTTAAAAAAATTGAAAACGACGAAATTAGACCTAGTAAAAATTGGATTTTCAGGCATATACACGGGCGTTTGATTACGTGGCCGTGAAAAACGGAGAAACTCGGCCGCGTAGAAACAAAACCGAAAATTGCAGAAAATCCAGGAATTATTTTTAATGACTCCGAAATTTCTATCCCCGATTCCGAATTATATATATGAAAGAATATATACTTCTGAAAAATTCAAAAAACCTTTGCTCACGCCACTAATTTGCTGAAGAGCCCAAAATTTTTACGATCCTGCTATTTCGGCTTTCTATCCGGCAGCTGAATCTGTTGCTGGACGTGGATGATGATGGTTGCTGAATCTGCTTCCGTCTGTGAAACCTTAAGCTCTCACTCGTCGAGCATCTCCTCAAGATGTTTCACATTTTTCTTTGATCCTCCTTCTGAAGCTTCTGCTGAAGCTCCAGCCGTGTCAGTCGTCCAATCATCCACAAAATCACCCGCCGCCGCCGAAACAATCATCATTCTTCAACTGGATCATGATCACCTCTCAGCATCCCGAAAACAATGAGTCGCCACAATCTCACGACGTCGGACATAATAGAGCCTTCGTGTTCTCCTGAATCCTATACTTCTCCAACATCACTTTAGCCACCTCGGCAGGGCCTTTCTCGCGTGCAGCCGGAGCACATCCTCCCGAAAGTGGGGTGGAAGACGTTGAAGTGAGTATTCTTGAGCGGAGCTCATCGTCTGTGGTTAACCGGAGCCGGCATATCGCCGGGCTCTCAACTGTACGATTAAATGAGCTCATTGCCGATTTGATGGCCATTCTGCAATGTCTCACGTAACGTCACCTTCTTGCGAAGGACAACGTGGAAGGGCAGTACGTGAAGCTGGAATTCGATGAGATCCGAACTATGGGATGATGGTGTCTTCCAGATGTAGTTGACCTTCTCGATTCAGTGCGAGCGCTTGTTTCGCAGATTTTGGACGTTTTGTGATGCCGTCTGAAAAACAGAGAAAAAATTGAATTTGGAGCATCTTGAATTTGGGTCCTTTTTTACTTTCCTACGGAACGTCCCACTTTATTTTTCGTGGTTTTTTTTCTGAATTTTGGATTACAGGGAATATCTCTCCAAACCAAGTACAGGGAATACCAAACTGTGTGGGCCGTCGCAGGAAGACTTCTCTACACTTATAAATTGTTTTACCTGTAGGCACATAAAGGAAAAGAGCAGAGCCTGCATCTTTGTATCTTCGATAAATTCGAGTTAAAAGTTCTTTTGTCTCTATTCATTTGTCATATTTTCCAATGTTTTAAAAACATTTTTTCTAAACTTTACAGTAATTTCGAGCGGGCTATTTTCACTATCAACTTTTTGACGCGTTTTTAATTCTTCATTTCAACCTCAATTTGTGCAAACTTTTCAAATTTCCATATAATAGGGCCGATTTGAAATTTTCATAATTTACACCAATATATTCAATCTTTAACCTCATTTTTTTCACAGAAATTCCCAACATTTTCACATATTTTTCATGACAAATTTGTATTTCAATGTTTTCCAAACTTACGAGGAATGGTGCTTGCCAGATATTCTCTGACCACGGAACCATCACACGTCAAATTTCTTGCATCAACCTCGAGCCCATCAATAAAGAAAACGAATGCGGCTTTGCCAGTTGTGGCTGCCGGAAGAGCCGGTACTCGATTGTGGCATAGGGACTCACTGCAAAAAAAGCATCGTTTTTTATAGAAATGGATCGATGTTTGTGTATAACTTTATCGATTTGCTAGAATATTATCGATTAGTTTCCGAAAAAAAATTTTAAAACAACCGTAAAACTGTATTTCTATTTTTATTTTTTTAAAGATAGACTTCCAGATCATATTTGTTTTGAAAATTTATAAAAAATTATCGATTTCTCTATGGAAAAATATCGGCTATTCTCGAAACTTGTGGATTTCCCTAGAGAGTTATCGATTTCTTCAAGGAAAAAATTATCGAATGTTCTAGAAGTTGTGCAAATTTTTCATAAAATTATCGACTATCTTTTACTGAAATATATAGACTTTTCGCCCAAAAAGTACGTACATCAAAGAAGGCTTATTGACAAGAGAGTAATTGTCGATTCCTATCATTCCAGAACTCCATATCCAACAGCTGAAGATACAAACTACCATCATTGGCGGCTTGTGCTGGCACAGCAAACGGGCATTCTTTCTCGCATTCCGCCATATCCGACACATCATTATCATACGATATCATGTATCTGCGTTGGCTAGGGAAAAATGGATCCTCATTTACACGCGTTGAGCACACACTTTGTGAGCCTGCGAGAGCTCAATGAGAACCTATGGTTTTGTGGCTCGTTTCGCGATTCGCAAATATCCGCCATGCATTCGTGGTAGCTCGCCTTCCTGATTATAGTCGTACATGATGCGCGCATGGCTTCACCACGAGCCGTGATTCGGTTTCCATATGTGATTGATTTTTTTGCGTAGTCGTGGCGCACGTGGATTGTTATGGAATACAGGAATACCAAGTGGAATGTTGGCACGTTTTGAAGTTGGGCCCATGTTGTGGGCCTTTGGTCTGTGAGGGCTTTGGGATATTATTACGGGAGGCATAAAATTCTGAGAATGCGCATTGCACAGCATAGCCCATAGACCAGATCCGTAAATCAACACAAGCCCAACAGTAGTTATTTAATAAATTACTGTAGTTTTTGCTGCGAGATATTCTGCAACGCGTCAAATGTGTTGCGAAATACGAATGCTCAGACGTAATTTTTCCTAAAGCTCGTCTATTTTTGTTTCATTCAGGGTTACTAAAAAAAAACCTGTTTTTAAAGCTTCTACATGTTTAAAAAGTTTTGAGAATTTAATACACTTTTTTTAATAGAAATTTGGCAGATATTTTCATCACCTCATCGACGATTATTCTTTTTGAACAATTTTCGATTTTTATGGGAATATATTTATATTCCAAGAAGATTAACTTTTTTTCAAGAAATATGAAAATTTATCGATTTTTCAAAAGAGATTAATTTATCAAAAAAAGAATAACTTTTCCAGAAAATATTTGTTATTTTCTTAGAAATTAAAAAAAAATTGTTAAATCGCTACGAATTTTGTGTCAATTTTTCAAAAAAAAAAAAGAGGCATCGAGAATATCCCATTTTTTTCGAAAAAAATTTTTTGGTTATCGATTTTTCTTTTTTTAGATAAAACGTCTCGTATATACTTTTTTAAAGATGTTTTTTCACCAACAAATTTTGATATTAAAAAGTTGGAATTTTATTACTAAATTATGGAAAACGTTTTCGATTTTTAGAAAATCGGAATTGAAAGTGGGCGCAAAAAATTTAATTTTTTAAGAAATTATAAAATAGAGATTATGCTCATTTTGGTATGGAGAGCGTCGATTTCCATCGGGCAAGATTTTTTTGGTTGTTTTCCCTCCATGTAACACCTGAAACTCGAGTGATCCCATGCTCATCACAAATCACAAGCTCCGACTTTGCGAATTTTCGTCCCCGATAGCACGTCGGATTCTGTTCATTTACATTATTAGACCATGGCGAGAAGTCGTCACGATTGATGTCCGTGTGGAAAGAGGGCTGGCGACGAAGAATGCGTACGCACGAGAGTTACGAAGTGCAGTACATTGTAAGGTGCCGGCTTCGCGTAGTCAAGCTCAGCAGACCACGTTCTTCGCTGGAAATATGATGACTATTTCGAAACATTTTTCGAGGAAAATGGATAGAAAAAACGAAAAATTCAATTTATTTCAAAGTTCGCTTATTGTTGATGAAAACATTATTACGGGAACACAAAATACTGAGAATGCGTATTGTGCAAAGTTTCTCGCGAAAAGTGTACTACAGTTAGGTGTTTCTTCAAATGACTACTGTACCTATCCTTGCGATTTACGGGAATAATTTATCAATCGATAAAACAGTCATTTTTAGAATTACCGTAGTCCTCGCCACGAGATATTATGCGCGTCAAGTATGATGCACGCATTCTCCAAATTTTGTGTTCCGTAATAAAGTAAAATAATGTTGTTAGATAAATATTCAGGGTCTCAACAAAATTTAATCTATGTTATCAGTGTTCATGTTTTTAGAGTGGAAAAGTTTTTTTTCAGAAAACAGTCAGAAATGTAGATTGTGTTGCATATTTAAAAAAATCATTTAAAAAATATGAACATTTTTTTGAAAAATCAAATTTCTCCAGATTGTATTACGCCATTAAAGGTCTCGGCACCATTTTGTTTCAATTTTTTGAAAGTTTTTGAAGTAGAAATATTTTTTTTATGAAAATTTTCCGTCGTTAGAATTTCGTTGAAAATTCGCTAATAAACGGGGAGTAAAAAAAACGAAATTTTCCAATTTTTCGAAAAACAAAATCGAAAAATTCCTCCCAAACTTACACATGGTATTAGCAATCCACTCCAACATGGCCTCAAACGTGCTGGCGACCCTCATTATGTCTAACAGTCAAGCACACTAAATATGTCCCGTTTCCAATTGCCGGGGATTCTCAAAATAGGGCGCCGGGTTCTCCTGCGGCTAGCGGATCATCGTCAAACTCCAAATCGTAGCCAATGTTGAGCACATCCTCTTGAGACATATCCAACAAATCATCGTCTAGCAGATGTTCCCTGAGCGTCTTCAGCAATCGAAACATCTTGCATTAACTGATGTTGCTGCTGCTGGTGCTGATGGGGTTGAAGCTGGATCTGATCTAGGGAATCATTGTGATGTCCCGGATGACTTCTTCTTCCACGACTTCCAAATCTTCTACATCTAGTTAAATTGTTCTTCATAATTCGGTGCGGCAGATGATGTAGATGGATCTTGTGATGTATCAAACTTCTTCATGGATGATCGTTGATCCATTTCGATCATCTAACACCTCTTGATGTCCAGGTGTTCCAGGGTCTGGTTTAACAAACGGACACGGAACCGAACCATCTATCACAGCTATTCATATATATAACACACATTTCCGATCGTAATCGTTTGCGTTGAATATAAATGAGACGCTTCCGAAGACGGGGGCATCTCGGCAGGACGGACATTGTTTCGACGAGACACAACTGTGTATTTAGAGTGCCAGCCCCGCCAGCCGTGTCTTTTGCCATTCGGAACTGGCCGTTGTCGTCTTGGACGATGGCGAGCTGTGCGGACGCGGGTGACGGACCTTCCGAGGCAGCTGAAATTAATCAACCTACGGCACTCTGTACATCTCCGGCACCACGTTTTCAGATCTACCCTCAAAACAAGATCTACTATTTGGAGATCTACGAAACCACTACTTTTCAAGAAATGGTACCATTCGAATTGCATCGCAGTATTCTCTAAGAACAACAAATCCAGAATGATGACCGCCCATTGTGCTCCGATGTCGGGTGTTGTTTAGCGTTTAGAAAAATCTTTTTTGAAAGAAAAACTTCAGCCGAGAGAACGATAAACAACGCACGATGAGTAATATGGAAGAGTTTTTGTTTCGTTGTTAGGAACACTGAAAGAGCTAGATCCTGAAAACGTATATCTTGTTTTGGTAGATCTTATTTTCGTAGATCTTGTTGTAGAACCGGCCAGATCTCGAAAACGTGATGCCTAATCTTCTGCAGTTGGCGAATTTTCACATATTTCAAGCTAACATATTTTTTCTTAAGCTTGTCCATCGATTTCTTCGTTTTCACGATTTTTTTCAGAGAAAATATAGAAAATCGATAAATTTGACGTTAAATTTTCGATTGAAAAAATGGAAAAATTACAGGAAAGTATTGATGGAGATTTAAACTTTCTAAACAATCGAAAATTATCCTTTTTCTTCTTTTGGAAATTTTTTTTTGGATTTTTCCCAAAATGGGGGATTTGAAATCAAAAAGCGTTAAAAACAAATACTTTTCTTTTAAAATTACCGGAAATTATTTTAGAAAATTTCCTAAAAACGTCAATAAATTAAAAAATCGAACAAGAGAAAGAGTTATTAAATTAAACAAAAACAATTTCACAAAAGTCGATAGCTATTGATTTTTCATCATAATTCCCTAAAAGTCGAAATTTTTAAACCTTCTGATAAATTCTTTTTTTGTTAAAAATAGAACTTTCGATTGATGAGAGAGACGTTTAAAACTTTAATAACTTCCTGTAATTTGTCCTATTTTTAATCGAAAATTTACAATTTTAATTTATTCATTTAAAAAAATCAAAAAACGAAGAAATTGTCCGTTTTTCTGGAAAAATTAATTCTTCGGCTCGAAATTTCGATGATTTGTTTTTAGAAAAAAATATGTAAAAAATTATAGAATTTCAAATAAAACACTGTTTTTTTTCTTTTGATCTTGAAATAGTAGAGCCCGAATTTCTTCCATAATCCAATTGTTCACTCAAAATTTGAAATTTTCGCATGACAAAATAACTTACGATTAACAGTCAACACGGGACCGTCCCTGATCGCCAGTATGATTAATCTTACGCTTATTTCAACAAAATTCGCCGGCCACAAAGTGCACAAAAACGCCGGTTGTCGGAATACGTGGCGGTAGGTACGGTGGCCATTCGGCGATTCAGACAATTCGATTGGCTCAGCAGCTCGGGCTCATTCACCAAATATCGGAACGGGAGACGCCTCTTGTTGTGGGTGCCGACCCAACCTCGAGTATGCAAGTTTTACGCGAAGAAACAATGCACCATCCTTCCACTATCTCGTCTTCGAACTGGGAATGTTTTTTTGATGAGAGAAGTTAAAATAGTAATCTTTAAATATCAGTTTGAATTCGCCGCATTTCAGTTGTGCACCTTTCGTGTATATTTACGATATGTTTAATCTTTTTCAGATGCTGATTTCCGATCTTTAACGGGTTTCCTTGATTTTCGTCGGTTTTTTTTGGATATGTGTTTTTGAGGTCGATTAATGAACCATTTTATTATCAGAAAGCTAGCAAAATGTTAAATACTGGACAGAAAATCCATATGCCACATGCTTTTCTCGACTGAAAACCGGAAATGTTGCTAGTTTTTGATAATAAAATGTTAAATTAACACATTTTCAAAAAAAAAAACAATTCTACAAAAACCGGTGCGACGAAAATTCAAGAATCGTTGCATAAACGGAAATCAAGACCCGATAAAGATTAAGCATTTCGTAACACCGAATTTGGTAAAACGACCACATGGCATCTCTAGCCCGAAAATTCGAAATTCTTCCAGCTGAAATGTCCATTAAATCAGGGAATTTTTCTGAATATTTCACTTAGATTAGGGATCAGGAAAAAATTTGGAGTTATAATAAAAAAAGTTACTAAGCAAAACGTTTTAGCAATTTAGGTTCTAATAGGCTTTACAAATATCAAAAAGTCCAGATTTTTCAATATATATATTTTTAGAGCCACAGATTTTTTGCTGTTTTTCAGCATTCTCGGAAGAACATACCGGTGTGGATCCGGGATCATCCAGATCTAACGAGACGTGCGGATCAGTTGGATCGACCATCGCATGTCTTAAATAGTCGTTTCCGTGCGGATAGTTTTACGATTGGAATTTCACCGGGACACGTGTAGTCGTAGAGAATGAGCACGTTTCCTTAGATTTGGCCATCGCCAATGGGAGAGGTTCCCTAGAAAATCTGGAAAAAATTTTGTGAATGGATTTTTTCGTTCTGAAGCATTTTTCTTGAAATTTGAAGGAAGACGGGTTTTGCATAGACTCAAAATTAACCCTTTAGAAAATTGTTACGTTGGCTCAAAATATCGAGAATAAAACAATTTTTTTCTAAAATTTCGAAAAAATTGGCATAATGGCGGAAAATGTAATTTTATTTGATTATTGTACTCGCCTTTTTCAGTTCATTTTGGGTTAAGCATTTTTGGCCCATAGGCTTAAAATTAAACTTAAACATTTAAAAAACGAAATAAGATATCTGCACAAAGCCAGTTATGGCCACTATGAACTAAAAAAAACATTTAAAAAAAACAACTTTTTTTTGAATATTCACACTTTCTTAAACTGATAATAAACCTTTTTTCTCAATCTTAACAGTCTCGGCAGCCACGCGCTGTACTCGGTGAGATGAAGTCGGCGATACGTGGATCCTTGTCCGATTGGAGCCGTCCGTTGAGACGAGCAACCGGATGACGTCGGACATTCGGTTTGATGACTGGATCAGTGTTGCCTACGTCGCCGCCAGTAGAGCTCGATAGCTTCAGATCGTCATTCGAGACGTCTTTATCGACATGATTTTGGAGCCGTCCACATGCGAAACAGGCTTTGTGTGGAACAAGTGGTGGGAGACGGGGTTTGTCCAGAAGCCAACCTCCTCCGCGACTAAAAATGGGGACCGTTGATTTTAGTTTTTTTTTTCTGGATTTTTCGGACAATAGCATTTTGACCATTTTCTTTATTTTTAGAAGTTATTTTTCTATATTTTTTCTCTAAGAACTATTGTAAAAAATAGTTCAATTTTTTTGAGGTTCTGGCGACAAAAATTTATTTTATCGAAAAAAATTTTTTTTTTTTAAAACAAGATATAGATTTATCACTGAAAATTACTAATTTCCAGTGCAAAAAATTTTTTTGCCTATTCTGGTAGCTGCCTGATTTTTGATATATATTCCAACACAATAAAGTTGCTGAAATTTTCTCCTTTTTTCACTGTCTCCGTACATCATTGCAATTTCGGTCTGTTCGCGTTGGTTAGCAGCTCATTTATTCGTTCATTTCTGTGAAGGTACGCCAGGCAGCCTGAATTGTGGCGTAGCAATCACCGTTTTTCGTCGAATTTCACCTTCATCTTCGAACTGCAAATAGACAATCATTGAAGAAAAAAAACGTTAAAATCCGACTTTCTCGATGATTTTTATGATTTTTAACTGAAATATTGATTTTTCGGCATTTTCTGAAGCAGATTTTGATTAAAATTTGAAGGTTTTTTTTCGTCTCCCGTAGGCTCAAAAAACGCCCTTTTTATGGCGGCTCAAACGCAAATATTAAGTAATATTCGAATACAAAAGTTCATAAATTTAGGACCCCTGCGGGGACATTAGACTTCAGATCTAAAACTAACCGATTTTGAATATTTTGAGCCAAGTTTGGCCAAATAGGCATTAAATTCACTCCAGATGACTAACACGTGAAAAAAGTTAAAATTAGGTAAATAAGACAAAAACAGAAAAAAAATAACTTGAAGCGAAACTGGAGCCCATTTTTGGAGACAATTCTCATTACAAAATTGGTTTTTTGGGAACATTTTTTATTCAAGTTATTTCGGACATTTTTTTTCGAAGAATTCCCATAAAACTTCGAAGCTTTTTCGGCATGTAAGCCCCTACCAATTTCACGCAATCTGGTACTGCCTTTCAGCAAGACCCAAGTTTACTGATAACTCTCCTTGAACTCGGAACATTTTCGACGGTGTCGCCGCCGCTGGATTTATAATTCTTCGCATTCTTCTACCATCGTCGATATACGACCCATCCGTATCCATTGGGCAAGCTTGCGTGTTCGGACACGTCGCTGTTTGCTGGGCCTGGAAAATTTCGATTTTAAAGTTTTTTAAAATAAATAATCCCCTACAAATTAATTTCCAAATGCGGCGGTTGCCAATCCATAAACCCGTCGTCCTCGTCCTCATCATCACCGAACGGGTCCATTTGTATGCGATCGCTCGTCTCGATATCTCGAGGGGAAAGGTTTAAATAGGCGGCTCATCCTCTACGATGACCTCCGTCTCTGCTCACGTGTACATCGTGTCGTCGCCGGCGAAGATCGGCTCTCCGAGCTCTCCGGCGGTGAGCTCCTCGAAATGTGGCGCTGGCTTTTAAGCTCTTTTTCACGTTGCGAACCGTACTTCCCTACGTCCTGCGTTTTGGAGCTGCGATCGAGCTCGTCTTGTGGATGCAGAGGCGAGCGCTTCTTCCTTTGGGTTGCCCAACTCGTAGTCTTCATTGTTGTAGAGCACGTGGGGATTTCCGAGCATTTCGACGTGGACGATATTTTGTGGCTGGATCCTGGGGCTCTGCGGCCGCAGGCTCTGGATTTGGCTGGGGCTCTTCGGCCGGCTGGCCAATTGGGGCTCTGTTGTGCACAGGAGAGAGCGCTGTTGATCAACTTGTTCCTGATTTTCTGCCAATTCAATTTTCAGGATTGACATTCTTCTGCAATTTAATAATTGAAAATAAGAATAATTAAGTGGAAAATTAAAAATTAAACAAGCATTAAAATAAATTTGAACAAGTCCAGATTTGTAGTCCGCAACGCACGGACGAACGCATACACCACAACTAAGAGAGACGGGAGGAGGGATGGAGAATTTGAAAGAGATGGCTAGGCGACGAGATAGCCGGAGGATTGAGGAAGGACAAACACACAGATGTGGGTTCTTGCAGCGCTTTCTCTGCGTCACTTCTTTCGACATTTTTCGGTTCAATGGGAAATTTCTACTTTTTCGGAGTTTTTCTTTTTTTTCATCGGAAAACTTCAAAAAATTCAAATGGAAACTAGGAGCTGTACGGACAATGCATAGAATAACACGAAAAATGCACATTTTTAGGCCTTAGGTCACTGTTCCGGCGCGGAAATGCGGATCAATTTCTTTTTGAATTCAAAATAGAGAAACTGGACGTGATGGTTGGTACAAGCGTTTAGTGAAAATGTATCACAAAATAGGAGATCAATTAGATATGTTAATTTATTCGTGGACCAAATGACTATAAAAAATTGCGAAATAAATAAAAGTCGATTAAAAACAATCATATGTCTTCATTGCTTGGCGAGAGTTTCTCGGTATCGGATAAACTTATCTCCTACAAGAGACTTGCGAATAACCAAAATAGTTTAGTAATCTAGACATTGGGTGGGGTGGGCCCAAATATTGAATAAGGGTGAAGAAAGATTATTCAAAATACGTCGCTGAAGTGTTGGCATACAATATTGAGTCGGATAAATGGTAAGAAAGCATCACCACTCAACTCAGATCACAATCTATTTCTCTGAAGAAGAAAGGGACGAATGTAGTAGCTTGCTGAGGGGGGGGAGGGAAGGGCGTGGGGATGGAGGCAATTTCAAATAAATCTGAAAGCAAGTTACAAATACGCACAGCCAAAACGGTGAGGCCGAGACTTGGCAAACCCAGTGATTGCAAGAATTCGATAAAAAGCTACTCGCGGATGTTAAGAGCGAATCATTTGGATCTCGGGGGCAGTAAATTAAAGGGACAAGGCATTTCGAAAAATACACACGTTAGACTGAAAAAAAAAAACCGATGTGATCATTATGGGATGCATCACTGCTTCTTTGGTGGGTCGAGTTGACACTGAGGCGAAGGAATGCGGATTGTACCGCTGCCACCGCCATATCCTTGTCTGTCAGTTGCTACATGCTTGTTGGATACAGATTTGTAGATTCCGTCTGTATAAAGCTGCTTCAACGTTGGTGCCGAGGGCAGATGTTTCTGAAAAATAAAGATATATCAGCGCTATAGATTAGTTTTACTTACCAATAAACCACAATTGATTTCTTTCGGTGCTGTAGATCTTGGCGTCCTCGTCTGTTGAAACTGATTGCACTGTAGCAAATGGCGCAAGTCGCTACCCTTGATTTCCGATCAACATAATAACAATGTTATGATCGGCGTGATCACGAAGCTCCTTCAACTATCGCTCTACATTCTCTTACGTCTAACATGAAGCTTAGTGTCGTAGACTAGGAGAGCTCACAGCCCCACGATAGTAAGCGGATATGATGGCACGGTAACGTTACTTTTCTGTCCAGCAGTATCCCAAATTTGAGCCTTCAATGTCTTGCCTTCTACCTATGACAAAAATAATAATTTGAATCATAACATTAGTGTATGCTACTGAAGTTCCTCACCGAGATGCTTCTCGTGGCAAACTCGACTCCGATTGTTAATTTTGATTCCAAGTTGAACTCATTCTTGTGAAACGAATAGACAGGAGATGTTCATCGACTTTCCGACGGCTGAGTCTCCAATCAGAACAACCGAAACAATTTTTCGTTTGGGAATTGAAAAAAACAAAATTACCGTTGAAACACAATTAGTCGTACTGCATCGTCACGAGAGCCCATCTTCTGCGCTGTAAAATGATAAAGGACTTGTTAAGGTTGAAAGTTATATATTAGGACGATTGTAAAAAAGAAAAAGGGCATTGGTCTCATGATTCATCAGCCGGGCGCAATGTCTTGTTGTAAAATCGATATTGAAAACGAACACTGTTTTATCGGCGGAGCATATTTCTATGTTCTGTTCCCGACACAAACGCGGAGTCAGCAACCGCTATCTCGACGCATGGGATTGAAAAAATAGAAGTGAACTTAATTTAAGAATGATTCAAAGTATATGAGTTGGGAGTTTTATATTGTTATCAATATATGAGGGGGGTGTCACCTTGAAGGAAAATGTGAAAATGTATATAGAAGTGTGTTAGGCTGAAGAGTATTTGAGGCATATCATACCCGAAAAACAGGGAAGGTGAGCGGCCACTTTGTTTGTCGACACGATTTCGAAATAGTTGAACTATTTTTTAACGGGAAGAAGCTTTCTCTGGGTGTTCTTTTTTGATATTTTCAGCTAAAAATTGAAAAAAATAATTAGTTTTATGGCTGTGAACATCCACAACATAAGCTTTTCCGAACGCGAAATGCGTGTGAAACCCAAATAATTGAACGTAACAGGTCCACCGGCGCGGCCACGGCGGTCTGAGGGTACGCGACGCTAGCGCAGCGCAAGGCCGGGTCCCGGCACGACAGACTACCGTATCCCTTTAGCAGCGGCGCAACGGATCGTATCTCAATTACATTTTTTTTTTTTTGAGACTAACGATTTTTCCGTTTTTTCAGAGCAATATTTTTCATTGATTTTCTTAAATTCATCAGAATAAATTTTAGAACCTAATTTCCCGTAATTCTGATACGCGTTTTTAGTTTTCGTGAAGAAAATGCTGATTCGAAAACTGAAATAATTTAGTTTTGAAAACTTGCTCTGAACTCTGTTTCAATATCTTATAATTTGCTTCTTTTCTGAATATTTTGATTTTCCTCAGGTAACCAACCGCCTATACTCCAACGTAAGGTTTTTCTTTAAAATTTATATTAGATTGAAATACATTAGTTTTAGGCCTGATTTTCAAATACTTCAATTTTGATATTTAATTGTTGGTTTTTCAGTTGAAAAGAAAGTGCCACAGGTTCCAGAAACTGTGCTCAAGCGCAGAAAGCAGACGATCCTCGCACCAAGGCTGGTCAACATTATACTAGGTGACCGTCTCTGTAAGTTTATTTAACTGTCTTGAAAGAAAACCGAAAATGTTCTTGCGCTGGTTTTAGGATCCACTATTATCCAAGGCTACCAGCAGTCAAAACTGGAAGCTATAAGATCTTGTTTTGGGTGAGGTGTATTCAATTCAGAATGCGTCTCATGTTTATAACACGATGACAATTCGAAATTTTACAGTTTAAATTGTCTTTTAGGTCCCGTTTGAAAATTAATTTGTACTAATCATGCATTAAAAATAAAATTTTTTACAGAAGAACAAGGGAAGAGAGAATTCTTCAAGCGTGCTGAGAAAAACGTCCAGGAGTACTCTAGAAACGCCCAAAAGGAAGGACTCAGACTCAAGCGCGAGGCTGAGGCCAATGGGTGCGAGACTTCTACGTTCCAGCTGAGAAGGTCGCCGTCGTCAGACTTCGCGGTATCAACCAGCTTCATCCAAAGCCAAGAAAGGTGAAATTATGTTAATGAGTTTTTTAATAACCATTCGTTTTCAGGCTCTCAAGTTCCTCCGTCATAGTCAGATCAACAACGGAGTGTTCGCCAAGCTGAACAAGGCTACTCTTCCACTTCTCCGTATCATCGAGCCATACGTAGCTTGGGGTTATCCAAACAACAAGACCATCCACTATCAGAGTCCTCTACAAGCGCTAATCGGATACGCCAAGGTTGACGGCCACAAAACCGCATATTGCAATCACCGACAACACCATCGTCGAGCAGAGCCTCGGGATAATTTGAAAACGTATGCCTTTTAATTCTTATTTAATTGTTTTCAGGAAAGTTCAACATCATCTGTCTTGAGGATTTGGCCCTGGAACGAGATCGTCCCTACCGTCGGACCACACTTCAAGGAGGCCCACCAACTTCTTGTGGCCCTTCAAGTTCAACAACCCAACTAAGATGGACTAAGAAGACCAACCACGTCATTGAAGGAGGAGACTTCGGAATCAGAGAAGATCAAATCAACAACCTTCTCCGAATAATGGTCTAACTTGTTTGGTGTTCATACCTTCCTCCCGGATAAATCGTTATTGTTTGACGTTGTTTAATTATGTGCATAAATAATCATGAAACGTTATCGTCTTGGCTCGACTCATCTCGGATTTCATGAAGGGTCTCATCATTCAGATGAATTCGTAAAACCGCTTCCCTTGCTGACTACTCTCCCAAGAACAGTCACTGTTCCCTACTATGCTCCATCCTGTTTATTTCTAGAAACTTCGAAGCGATCCTAATTCCCTATGAAGTGAGAGAATTTAGGTTCGTGAATAAACATAGTCCAGATTTAAATCCACGCAATGTCCTCTCTACAATGTACTCCCTCTTGAGCACCTTAACCCATTGATGATGTAGATGGGTATTTCTTCAAAAATTTGATGGAAGGACTTGATTATCTGCTCGCCAAACGATATGGAACAGTTGCCTTAATACTAGAATTATCCTTAGAAAAAGCTTAAATATTCTTCCAGTCTCTGGACTCGGGCCTGACTCCAAAAGAGCGAGCACAGGCTCTCGCATTGCGCACTTTGCTCGACGTGCTTGGATGCTTACACGCGAGGCCAACTACGGATTTCATGTGGCTGCGCGATTAAGAATAGACTTCGGGCTTGGTCAGCTCTATTTTTGGAGGAATTGGGTTGTACCCAGATGCAGAAACGGGTAGATTATTGATATTTTATGGAAAAATCGATAAAATATTGATTTTTTACTGGAACAAATAGATCAAAAATCGGTTTTATTTTCCTCGGAAAGTCAATGCCGCTGTCTGAAATTAGTAGTTTCTTGTTGATACAAGTTCGATAAAACTGGTTTTTCAGAAGCAAAATCGATATAGTAAGCCAAAATGACCAAAAATTATCAATTTTCCTATAATATTTACCTTGGTTAGATTATCGATTTTTAAGGCAATAAAGTCGATATTTCACAATTTTTTATTTTTTTTTGGCTTTCCAGCGCGCAAACTGTGCCAAGATCTAAATTTTCCGAAATTTTCATTTCTGACACGCCGCCGAGTGCGAGGCTACGGAATATCCGGAAAATCGGCATGCGAGAAAGGAGGTCGCCTGCCGAACAAACTGAAGCTGTTGGAGGCGGCCTCCCTGACTTTTGGCTCGAAAAATACTTTTTCGATGTCAATGCACCGTCTTTGGTAGGTGGCAGCCAAAAAACTCGTCGGAGCCAAGACTAGGTTTCAGCTCGACTGCAAGGCGTTCGCCGTGATGGCTCAAATATACACCACTGCAGAACGAGGCCCGCGTAAAACAATTCATCCCGAAACGATCTCCAAATTTGTTCGGTGGCCTTGAGTTTTCTAAGCCACGAGAGTTGAAAAGTTCTATAATAGGGCATTTGGTTTCAGATGACATTAGTGACGGGCACACATGAATCCAGAGGAATTCTGGTCGGATTGGTGTATCACGTCGGAGGATTGAATTTCGTGGAAAATGCTAATTGGTTTAATGTAATATGATTTTGCTTCGTGGATTTTAACCTATGCACGAATAAAATTTATATTCTAATTTTAAAAAAATTTCAAACCAAAGAATTTTGAGTCTTACGTGACAATTGAAGGGTATTGCAATATGGGCATAAAAAATATATTCCCTAATTTTCGAACTTGCTCAGTCTTGGTTGCGCAGGAAATTTTTTTGCAGTTCTTGTTTGGGCCTCGGAGCTTGCGCAGATGCATAATATTTGACGCGCAGAGTTTTAATTGAAGTTTGAGCTTGAATTGAGTTATTGAATTTTAATTAAATAAAGCGAATTCTAGATAAAATGATGTGTTTATTGCAAACTAGATCGTGAACCTACAAAACAAAGACTTTACGCGCAAATTTCCGAAATTTTCAAGAAAAACCAGTGGAGGCAGAATTTCAAATGATACTTGTTCCTCTTCTATTTCTTCTACCAATTTTGTTGTGCGGTGGGAATAAGAAAAAAGCGAACAAAAATGATGTAAAAGGCGTCGAAAGTAAACCCACTGGTTCCACCGTCGACCTCTACAGACCTGCTGAAGACTAAAGAGAAGGAGAAATGAAAAAAGAAGAAGCTCCGGGAGCACGACGCCCCGACTCAGCCGAAAAGTCCTCCGAAACCAGTGGTCCAGGACACGAGAACTTGGTTAAGTGCTGCCTAAAAGTGAGAAGGAAGACGAAATGAAGAAGGGAATTCAGTTGCGAATCCGCCGAAAAATTTGGTGGGTCTCACTGCGATACATTGAGTGTTTTATCGATTTTCTCTGAAATAATTGATTTTTTCTGTAAAATTTTTGACCGCGAGATTTGCGAGTTTTCTGAATTTTCAAATATGTCGATTTTTCAGAAATGCGAAAGTGAAATTTCTCAAAGGAAAAGCCGGCGGCTGACAAAGAAGGACGAGAAAAAAGAAGCAAGATGGCCATAAGGAAGAGTCGAAAAGAGGGAAAGGAGAATAAAAAGGAAAATGACCAAATTCTGTGAAAAATTTCGATAAATTGGTTCCTGAAGAAGTCATTGTTCATTGTCGCTTTTTCAGAATTCCTCGAAATTTAATTGGGCGTCATGCTTCATATGTTGCATTGAGTCCAGAGACTTTCAAAGTTCACGCGCAGCAGACATTTTAGCACGCGCTGCAGTGAAATTCCTCTTGGTGAAGATCTTGATTTTTTCCCGCCTTTTTTGAAAATTTTCGAGGCGTTGGTCGAGCCGAGTACATGTGAAGACGGAATGTCAAATCACAAATACATCACATTTGACGCGCAAAAAATTCGTTTTGAAAATATGCGCGTCGAATAGGGTGCATTGAGTACGCGGAGCCAATACTAATCACACTTTCTTATCGTGGAAAATGGAGCGAAATTTGATTTTTTGATATTTAAATATTCGGGAACAGAAAATTCGGAGAATGCGTATTTTGAAACATAATTGACGCGCAAAATACCTTCTCGTACAAAGCGAAAACTACAGTAATTCTTTAAATGACTACAGTAGCACATGTGTCGCCGATTGGGCGTGATTTTTATTCCATTTTCTTCAGTTTTTCTTGACATTATTGTGTTTTATTTTAATATTTTTACCGATTAATAAATGATTTCCGCAAGATAAATCGAGCTCACAAACGCTACAATTGTGTCATTTAAAGAACTGTAGTCTCCGCTGCGAGATATTTTGCGCGTCAAATATGTTGTGCAATACGCATGAATTTTGTGGGCACGTAATATTTGAGCGGCTGTTAGATAAAGATCAAAAAATTCAAAAAAAAAAAAGATGTCAGAAATCAAAAATTTTTTATTGACGCAATGCACAAAGTCTCCTGTTTCCCTTTTCCCCAAAGTTTTAAACTAATAATAAAATTTTTTAATTGTCCAATCCGACCAGTTTAATACGAAACAAAACGGACAAAAGATTCCACAATTCCGATTACGGCTCAACACTTTCACTCAAGGAATTCTCTACGCTTAGATTTTGATCTTAATGGAAAACTGGTAGAACTTGGTATAAAACTACACAAAACTGGCAGAAAGAGTACTCCTTCCAAGACAAATAAAGTCCCTAATCGAGGAAGATCACTTGGAGCATATTCTGCCGCAACGCGTTTCTGCGCCGTCCCTCTCCAACTCGTGTATTGCGATTGTGGTGTTAACACTAACAATTGCCTATCAGGCACTGTAGTGGTATTCATATAATTCACTCAAATTTGCTTAACGATGCCCATTTTTGCCACCTGGTAATTTTTTTTAAAAAATTCAGAAATTTTGATTTGGATATATTCAAATAAAAAAAAAGTCTAAATTTATTTGCAATCGTTTGAGATTTGACATACATTCCAAATCCTACTCTTCGCAATTTTTTAGTCAACTCAACCTCAAAACCTTAAAAAAAAACCGCAAACCTGTCATGGCGCATTACGTCGATGTTATCCCTACGATAAATCTTCTGTTTTCGAAGGGTTTTTCATTTTCCAATTTTTATCACCAAGGAAAATGTATACACCAAAAAATTATATAGAATGTGACGTGTAAATTGGCAAAAAACTAATAACTTGCGCTTAGCTTTAAATCACTGCATTGCCTCTGCGGACTCAACACACCCGATCTGAAATTTCAGGAACTTATCGATTTTTGCCTAAAATTTTGCTGCATGGCTGCATCGATTAAATATTAAAAAAAAAAGCTGTTGAAAATGATCGATTTTTTTGAACACGAAAAATTTGTGGAAAATATGAAATAAAAAAAAACATTGTGCATCGAAAAACTTACAGGCTCGATACCGTGAGCTCTGGACAGAACAAAACTGAAGATGGCTCGGAGTCGCGGCCGGGACGAGTAGCTCGTGGCCCGAACCAAGCGAGAGGTTAAAGGCACATGGCTCCTCGGACAGTCCAGACCGATGAAGCAGAAATCGACGACAGAACAATACGCCGAGGCCGCTGGCGGAGGCGGTGGAGCAATACCGAGTGTAGACGGGGCAGGTGAAGGACCACCGGGTGATGGTAGGTTTTTAGATTTGCGAAGCTATCGTGGTTTATTGGTTTAGTTTTACAGACGGGGTCGACGGAACGGAAGGAAAAGACGGTGCACCTGGAACCGATGAAAAAGAGTCAGGTACCACAAAGACCCGGCGACGGAGGTAATCAACAGGTACCATCTGATGCATTTGAAGCATGCACACGTGAATGACCACCAGGACCGCCTGAACCAACCGCCCGGAGACAAAATCTCGAGGCTACCCTGGAGAAATCTGGGAAGAGCCAGGCACCCGAAGCGCCGGACCGAAAGGAAATGCTGGACCGTAAGTGGAACTACAGAATCGATTCAGTCTGCGGTAAAAAATCATTTTAGGATAAAAATCGATAATTTTCATTTTCGTTTTCCTCCATTAATTTATGTTAACTTTCTAGAGTTGGACCAGGTCCACCCTATCCAGGACGACCTAGAGAAACCGGAGATCACGGAAAGACGATCGCCGGAGAGGCGCCACCTGGACCACCAGACGACAGAGGAAGGAGAAAGTCCACAAGGACCACCGGGACCATCAGGGCCACGTGGAAAGAACGGAGTCGATGGAGAGAAGGGTACGAGATCAAGGTAATCCGGGACCATATGGAAAACCTGGGCAACCGGGAGCTCCAGGACCCGATGGCTCTGGTGGTGAGAAGGGAGGTTGCGATCATTGCCCACCGCCAAGAACTCCACCTGGTTATTAAAGATTCTTCGATTAGTTGATATTTTATTTTATTTGATCATGGCGTTATTCATTTTATCCTTCGGTGAAATTTCTTTTGTTGCACTATGATAATAAAATTCTCTTGCCAGTAGTTCCAAGTGCCCCAACATATTTTGGAGTCCTTTATGTAGATCCCTCTCGTCGAAAGCTGGAAGATTTCACAATAAATCTTTCAGAAAAATCGAATGAAATTTTAGAAAAAAAAACATCAAATTTTTGACGAACTGCATAATCAGTCAATATTCTATAAAAAAAAATACGATCGCACAATAATAAACAACGACGCGGAACGACACAGTCCGCGGTTACTGAGCTCCGCCCACGATTTCATTTGCACTGCGTTGAGTCGGCCGTGTTGTTATTCAAGAGTGAATATACTGGTTAAGTTTAAAAAGTTGGGTGTTTAGTGTTGAAGAAAATAATTTTTTTATTTTGAATAAAGCACAATTGGCAGCTGAAACTGGATTAAATCCAGACAAATTTTGAACCGTGGTTGTTGATGCATTGAGTTTATATTGTTAGTCAAATGTATGAACTTGTAAAGTGCTTGTAAATGTAAGTTGCTTGTTCGCTCATTCTGAAACAAAATTTAAATTAAATAAAAGTTCACGCGTTGATACAAAAAAGCCAAACTTACTGATTGCAATAAAAATAATCATTCATAATAGTTTTTAACAAACAACAATCCAATGCGATCAAAAGTTCGGAAGGTGATTTACAACCAGAGGACACCCAATCCAGAGAAGATAAAGAGACGACTGCTACGTATAGTGAGGATACAAAGCCACGTAAATAGACCGAAGTAGTCCTACTTTAAAATAACAGTAACCCAGCTGCCTAAATATCATAATAAAACTTGCAAAAAAATGATGTAAAATTTTAGTTTTTAGACTTTTGAACTGGTAGAAGCTGTGTTAGCGCCACTTTTTGACCACGTCTAAATAGAAAAATTTCCCATTGTAAAAGAGTTGTATTATGATACACTGCGTGGCGTGTAAAATACCGAAAAATAAAAGCGCGGTTTTTTTTTTCGTAAAATCACAGGGAAAAATCCGTAATCCCGGAACTCCAATCAGCCGCCAACATCCCACGGGCCCAATAACTTCTGGGTTTTCAACAATCTCATTTACTCCAATTCCCGAAACCCAATGGGAAGGAGAGCTAAACGCGGAACGGGACTGCCAAGACCCCACGCTATCCAGTTAGTCGTCCGACCAACGCCTCTCACACCAGCCATCACGCCATGCGAAGCACCACCACTACCACCTCCACCAAACCCTCTAGCGATAATAACAACTTGAAACGATTGAAAGTCAAAATCAACTGATTGAAGTGCCCAGCGATGAAGTAGGCCGAGTAGATTAATATAGACAATTTTCTTTCATTTCATGGGAAGGAACGAGTGTGAGGCGATGTTGAGCAAGCATGAAGACGATTCGAATGACGGAAATTAGGAAGAGGCAGGTCGCGTATGTGATTAGTATCAAGCATGGAAGTATCAAAATATTCACGTGTGTAACGGACCAAGACGGTGGGAGTTGTTTGGTATTATCATTTAGTTTCGTTTCAAATCAGACCGAGATACATACATTGAAGTTCAAATTTAGAACATGTTGCATCGCAATGTTGTAGTTCATTGTGCTCCCTGAAGCATTTTGCGGACACCACGAATTACATAGAAAATAAATATTTTAACCTATGGTGGGCGGCAAATTGACAAATTGCCGATTTGCTGAATTTGCCAAAAATTTTCGGAAAATTGTATTGTTGCACATTTTTTTTAAATTTCAAAATTTCGCAAATTTTATCGGCAAAATTGTACGCATCAACCCTATTTTCTACATCTGTTCCGAAAAGTAATTATATGAAAATATCTTAAGAAAAGGGGAAAAAATTCGAAAAGGCACAGTTTTCAGTGTTTGCGTCTTGTACAAAAAAAATCTCGAAAAACTTTCGGCCAGCAAACCGCCAAATTGCCGGAAAGGTCTTATAGTTTCAGCTAGCAGTTCGAATCGGCAAACCGGCTATTTGCCGAATTGCCGCAGTAGCCTCTCACCCCTGATGCTTTTGAACATGGTGCATTGCATCACCCTCGACTTGGAAAGTTTATATCGGTAGATATTTGCAGAAGATGTAATTTAATGATATTGTTCAGAAAAAGCTCTGGACCAACAAGTACGCCTTCAAATCCATCTGTGAGCTTATTGCCTATCACAAGCGAAATCACAAGCAGATTTATGATGACGTTGATCTGTGGCCTCGGGCACGACATGGATGGCAGCTGAACAACGGGCAGGTCACATTGATTAAGAGCGAAGTTGGGAGAGGGACAGTTTGGAGAAGTGCACAAAGGATTGAAGACATCTTGCAGCCCCGGTCACTGTTGCCGTGAAGACCTTGCACCAGAGGAAGGCGGCCATCTATCCGCCAATGAGAAGATCTTGTTCCTAAGAGAGGCCAATGTGATGCTCACCCTGCACGGTCTAATGCTACCTGTTTCAAGTTGAACTAAACTAAAATTCATTCCAAATGTGATAAAATTGTTCTCTACGGAGTATGCTCCATGAAGGAGCCCATAACATGATTTGGTCATGGAGTTTTGCGACGAGAATTTGAATCCCCCTGGCAAGGACGCTCTACTCTCCAAGGAAGAAAAAGTGTCAGCTGAGGACAAGATTCTCTACCTTTTCCGCATAACGCCGCCTCCGGTATTGGTTATTTGCACGGAAAGGTTAGTCACAGGGAGCGGCGAGAAATTGTTTGTTGAATTCCAAAAAGATGTTTGTTTTTCAAAATTTCTGAAATGTGTATGAAAAAATAAATTTCAGCTGAAAATACTTTGGATTGGCGGTCAAATGAGTTGCTATAAAGGAGCGAAAGGGAGGATGTCTGCCGGTCAAGTACATGGCTCCGGAGACATTGAAGAAGGGGTTGTACAGTACTGCCTCTGATATTTCTAGGTGAGCCTACGAGCATACATATGACATTGGTAGTGGCGTCGTGGCCTAGAAACCTTATCCGCGTCTGAAGGATAATAACATCACACAAGTCTCTATGATTTCCAGCTACTGCGCTCAAATGTACTAAGTCTACACGGACAGAGACGCCATTCGAAACGTGCGGGCTACGTGGAAATGAGCTCCGAAAAGCGATCATCGGGAAGAGAATCAGCTTGCCCGTTGAGGTAGAGCTACCAGTCTTCATTGCCAACATTTTCGAGCAAAACAAAGCAGGCAGTACGAGACCGAAGATCGCATTAGCTCCAAGCAAATTATTCAGATTTTTAAGGAGGTTTGTGAAGCATTTTATCTGTTTTTTGTTCAAAAAATTTGTTATTTTCCAGGAAGTCGGATTCCATGAAATTGAGACAAGTGGGATACTGCATAAGCTTGTCAATTCTCCCTTCCGAGAATTCACAATAAGGAAAGTAAAGGCGCTGGCAGTGTAATAAATATCTGAAAATCCCCCCACCCCTGAAAATATTTGACTGTATTTTTTAAATCACACAACGCACACAAAAGACAGACAGAAAGCATAAGTACACAGAGAAAATGTTTGAGGTGAGGTGCGGAAGGGAGGCTAGAACCTACTTTACGCCTCCCTAACAAGTTATGACTTTTTGGAATTCAAAATGTCGTTTTTTGCTATTTCACTCATGCGCTTACGTACAAACCTTCCTACCTTGTCTGCCTACCTCCCTCCTATTCTCTTATTGCAGGATTTTTGAATTTTTCTGAATATAAGCGTCTGTCGTACTTGTGCGTCATTTGCAAACAGGCTGTTCTCCGTTTTAGGGGGTGGCAGCACCCACAAAAAAAGACATAGGAAATCGGACGGAGTGATCTACTAGATCAGATGAACATTAGACATCAGTTTGGACCTAAAGTTAAACATTATTAATTCACAATGGATTTTCTTATTGTATTTCTTGATATAGCCCGGTTGTGCGGTATTGATACCATTACAATCCACTAAGCTAAAGGCTGTCATGTGGAGCCGAATGAAAAAAATCCTGATGATACATCGAGCATGCGGCAGGCGTTGAAACTCGGCAAATTAAGATTTGCCGGAAATGTTTTGAGGGATTTTTTATAAGATTTAAATGTGACTCCCTTTCTGAAATGCATGTGTCCCGTAAGTTTTTTAACTTTAGATATTTTTATAGGATCTCACTTTTCAAAATAGACGTAGGAGAAATCATAGGATGCATACACCTTTGCCGATTGAAATTTAAATTCTGAAATCCTTCCAATAAAAGTGCATCACCACAAGTTGCCGACTTTTGGCAATTGCTCGTTTCTCCGGCAAATTCGACACACCTGGCCTAATTTGCCGATTTGTCGATTTGCGAGAAATTTTAAATTCCGGCTATTTTTCGATTTGCCAATTTGCCGAGCAATAAATTTCAATTCCGTCAACTTGCTATATTGATCGTTTGCCGCCCATCCCTGGTACGCCAAGAATGGTAGAATATGAGTATACTAAAAATATTTGAAGAAGAGGACTGGAGCTGGAAGAAAAATCTTTTTACCGAAGTCTTCTGAGACAATTTCGTGAAAATTGATTATCACTTTCTGACTCACAATTTTTAAAAAAAATTTCCAAAATTTTTATCCTAGTTCTCGATCGAAACTGGTCTTCCGACATGCAGGTGCTTGATTGGTAAGTATGACTGCCATACCAAATCAAATGAAAAACACGGTGTATCGTCTGGGAAAAACTTAAACTGTTCCGTTTTAGTAATTGGACAAGGATCTGCTCAATCTCGCTACTATAGCAACCGACATCTTGCGGGTCCAATAAAGATTGGTATATCTTGAAAATTTGATGCACGTTTATTTAATCGCCGCCACACACACACTCACAAAAAAATCAATTAAAGCACCCAGTTGCGCGATTTTAGTTTCTAGGCGCGACAAAAGGAGGAGAACCGAAGCATTTCCGCATTATGGCTCGTGTGTGTGCCGTTCCGTTTGTCCCGCGGCTCTCTCTCCCTCTCTGTTTTTTTTGTTTGCGAAAACTTCTCTCTCTCTCTCTGCCATCACTTGTCTGATGCGGATAACATAGAGGGAGGAGCAGCTTAGAATTGCGGAGGGCAAAATACCTGAAATGTGATCTCTCTCTTATTGAGTCATTGACTGTTGCTGCGAGAGCCTTTTCCCGCGCGCGCCTCCCAACTACCCGTCGACGAGCCGATTTTCTTGTCGGCGGTGCCATTCGCAATACACGTCCCTCTCTCTTCTTGTTCTAGAAACATTCGGATTTTTGATTTTTTGATTTTTCATGGTGGGTCTGAAGGCTTTTTTAGGCCAGACTTTTGGTGGCCAGGTGTATTTTTATTTCCAATTTATCATATTGCTTTTGTCCGACTTGTAGGCAAAGCACCTTTTTAAGCGCCAAGTAATTAAGCTGAAGTTTGGCTGCCTAGGTTTCTAGCCACCAAACAATTTTTTTGTTTTCACACAGCACACTTTTTTAAACACTGTCATAAGTTTTCAAAATTTTTTGAAAAATTTTACACCGAATTTTGAGAACTTTAAGTTTGGTGGCCTAAATGTTTTCAAAATTTTCTATGCCACTGAAACAAAAGTCCTAACTCTAATTGAATTATCTTTGAAACTATGAAAACTACAAGTTCGACTAAATATGGCTTACGGGTCCAATTAAACTCGACTGGGTGGCCTAGAAAACCAATTTCGCTTTTATTTCATTTTCTATGCCACCAATAATCTTGTTCGAACATTACTTTTATTTTAATTAGTGGAGTTTGGAATCTGCCATGGGCTGTAAGATGTTGCTCGCCTCTAGTTTCTATGCCAGGAACCAAAAAGTGGTGTTGGTGGCCGACAAACCCAAACTTGGACAATTGCATTTTCTCGGCCATCATTTTTTTTAAACTAATCGTTGTTGGTTTAGTCTACTGTAAAAAATCAAATGGATAACAACGGGAGCCAAGCTTTGGAGCTGGTGGTAGATTTTGTGCTAGGTCACTAACTGAAATGATTGCAGCTGTAACTATAAAAAATAATTTACACGAGATATATAACATCCAAAATTAGTAGCCTAATTTTAGGATTAGAAACTATTTAAACAATTGGTGTGTGGAATAGAAACTGTATTTTGAAATTGCCACCAATTCCAAATAAGCCTATTTCACTCCTGATTTGAGCTAAAACGCTGAAATTTAGGCCATATTAGAATAGGCTATATTTGAAAAAATGGAATTGGTCTGACCTAGAAAATATTTTTTTGAAATTTCTGCTCCACCAATTTAAATTATAGCATAACTCGTTTCATAGTTGGACGGTGATTGAAATTTTAGACAGATTTTAAAAACAGATTGATCCCTTGAATTTTCTAGGCCACCTCTCCAGAAAAAAATCTGAGAATTGTTTTTATTTCTAATTCAATTTCTTCGGCCGTTTTTCATCTCTCGAGGATCTTATCCCCTTGTCTTACGTCTCCCACCCGCTGCTATTTAGGCGCCTTCATAACTGTGAAAATTCTCACCATTACTTTCCCTATCTCGTTTTTGCCCCCCCCCCCCGGTGTCCTATCCTTGTTCGTACACCTGTTGTTCCATAACATCTGCCAACCAATTTTTTCCAATTTTGCCAATTTTTAGTCAAAAAAGTGCATTGCATCGGCAGGCATGCCTCTATAACTCGTACACACACTTCGCTGAGCATACTGGAAGAGGGAAAAAATCAGGGATTGTTTGGATTCCTGGCGCCTTCTAGGAAAAAAACTCTTCCATTTTTGTAGTGCACATCAAAATGATCAAGCTGATTAATTTTCAAGTTACTCCCATAAATACAACTGAGAAAGTTGCGTTTTAAAGTTTCTAGGCCATCGTGGGATTTCTAGGTAGGTTCCCTTTTTTAAAATAGCAGTCTTGCACTAAAGTTTTGATTAGGCTGTTAAATGCTTTTTGTCAGTACGTTTTTTGGAACGTCGATTTTTACATTCCTCTTTTAGTTATTGATTCCGTTTTTTGCAAATTTTTATTTATTCCATATCTTACAACATTTAGAGGGACTCAAAGTCTTTGATAGCCAAGAATTCACTCTAATGACGTTATGAGCTCCCAGACTATAACCTTTTTCCCTTTTAAAAAATATCTAAATTACAAACATTTAATACAAAAACTTCTCGTTTCGAAACGTTTCGAAATCCTCCATTTAAAAAAATTAGATTAGCATCGGAAAAATTGCGAAAATTTTGAATCTGAGTGTGGATTTTCAATAGGGGGTCGAAACCTCGCAGGAATTTGAGAACAGTACCCTTTCCATCGTCCTTCCCGAAGCCCATTACATCATTAATTTAGCCACCTTTCTAAAGCGGTCCTGGGGGGGGGGACATCTGTAGTTTGTTGCCTATACAGGGACCCCCGCCACAACCACCGCAACTAGAGAAGAAACATCTGCTGCACACAGACAGCTGGCACATGGATGGACAAAACTCCTTAATTTTAGACCGCGCTATTTCATATAATAAAAGTAGAACGGGAGGCAGAAAAGAGGATGACTGCGAAACATCCACCTGCTTGGCTGTCAGCGCATAAACTTTTCGGAAATTTTGGGTCCCACCACGCTTTTTTCGGTAGCAAATTTTGAGATATCTCGATACACCATGATGTCATTTGGTGGAATTTTGGGTTATCATGGCAAATACAAACCTTTAACGTGAGTGCCAAATTGAACTTTTGCAGTCTGAACTTTTGGCCATTACTTAAAAATTTCCATGGGGCTCTCTAAGCCATGTGGTTTCGAATTTTTCCTGAAAATTTAGATTTGGTCATGCACCATGTTGTTTTTTTTTTGGAATAATTGAGGAATTCACGGCTTACTTTTAAAGTAAAAAGTTTCGTGAGATCCATGTGTTTTCATGTTATTCAGTTTGTAAATTATACAGATTATTGACTGAAGGTTAATTTTTAGTTGGGAAAATAAAAATCGCCAAAATCAATAAACAATCGTAATCATTTAGAAGTTGGGAGTTTCCATATAGGCGGTAAAAGGCTTGTCTGCCTTACAATAATACGACCGCCGCTCGCCTCAATCCGCGGCGGAGCAGTGTTCAGTTAGGCACTGAAACCGCGTTCCTGCTTACCATGATGTTCCGTTCTTCACGTCGATACACCATGATAATGGGTTACATTTTGAGCCTTTTCGAAAAATACCATGGTGGAAAATTTCAAGCTGAATTTTAATATTTATTAACCGTATTGTGGGAGATAGCATGCAAATGTCTTTCATCTTGTGTCCCTTCACTCGAACGTCTTCAATTTTCGTCCGAACTTCTCGATGCACCATAATGCTGTTTGGCGATAACTTTAAGAATGGTAGAGATTGCGATGCACCATGACGTTTGTATCGATTATCAGAACAAAAATCACTCCGAGACCCAAATAGTTTCATTCTCGGCACTATATTTTCCAAGTAAATTTGAAAATTGCTTCTCGGAAAAGTTTTTTCACATGCACCTTTAATCTTCTGCTTTGGAAACTATGTAATTTCCGCCCAATACTCTATTTCAAGTTGCTCTCGATGCACCATGATTGTATTTTTTTCAAATTTCTTACTTTTTTTTGATTTTTCCATGAGAGCCAATATCTGTCTTTATAACGGTTCTGTAACGAAATTTTGAAATTCTTGCACGAGATTCTGCTCTCATCTCGACATGATAATTTTAAAATGAAATTTAGCGATTTTTCGGGAAAAAAACTGTTTCGATCAGATTTTCTAGTTATTGGACACTCTGCACCTTGCTTATTGCTGGAAATTACATTTTAAACCGACAACCTTTCAAAAACTGTTTTCGTCGATCTCTATGAGTGCATAATTTTGTTGTAAATAGCTCGGTGGTGGGCCGCAAAAAAACAAAAAAAACAGGTATAAAACGCAAATAAATTTTGTTGTAATGTTGACACCAACAGAATCGGCCTGGAACATACGGTAGATCGGATTTGCAAAAAAACAACGTTTGTTTCGACGTTCCGCCGCTTTTTATGGGAGAAGTAGTATGTACCTTTAAGGGTACCGTAGCCTTGACCCTATGGCCTAAAAGTGAACGGTACTAGTCCCAAAAAAAACAAGATGACCAGTTTCAATCTGTCAACATCTACACATTTCTAAAATCTCATTTAAATTCCACTGTTCGATTTTCGCCTTTCTTCTGTCCCAAAGTACCGTATCCTCATCCTTCTACCACCTTAATTTGCATTTGTTCTTGCTTATTCACTTCTTCCCCTGGACGAAAAATGTTGCACGACAACAACAAAACCCGCCCCCCACCATCTGTTTCTCTGAACCTTCGATCCAACTGTCCCCGCCCCCTTTTTGAAGCCCACTGTCTTTTACTTTTTTTCTTTGGTCGCTGATTATGTCGGTTCGTTTTAGTATTACAGGAATGCACTACAATAAATTCCCTAAACGCGTACCGCGTTGCACAACATATTTGACGTGCAAAATATCTAGTAGCGAAACCTAATCTATAGTTACTCTTGAAATGACTTTTGTAGCATGCCGATTTAACTAAATTATTTATTAACAGATAAAATATTAATAGACACGACAATTCAAAAAAATTCATTTCGTAAATCGAGCCCGTAAAGACAAAAGCGCTACAGTAGTCATTTAAAGAATTACTGTGTTTTCGCGTACGAGTTATTTTGTGCGTCAACATATGTTGCGCAATACGCATTCTTATAATGTACCCGTAGTATATTTTTGTCTCTCTGATTTCCCTCAATTGCAATCTTTTAATTCCAGATTTTTTTGGTGAAATTTCTCCGCTCCATTATCAATTTTTTTTAACCACATAATTATTAACCCCAAAACATCGCAGATTTTCAGGTAAAATGCCAGGGCGTCGTGAAGCGTTAGACCTTTTTCTATGAGTAATGGTGAGCAATTTTTTTGAAGTTTTTTTTTGAAATTTGTAATTTTCCAGAAGGCTTCTGCAAACGGGCATGACACGTGTGAACGACGCCGAAATTTTGGCAACCGTGAGTTCGGCAAATAAGCTAACAGTCTAAGAAACACGAAAAAAAATTTTCTGTTCAAGATTCGTGATTTTCGGATGATTTTTGAACTTTTTGTTCCGACGAGATTAAAGTTCCCACTGAAAACCCTCTCTCTAAAAATCCGCTGCTAAAAAGCCTCAAATGGCCTTGCGAGAATAGACGGAATGTTCAGGGATGACTGGTTTAAAATCGGCGACCTGTTGCCATTCAAACCGAATATCTCATTTCGAGTCCTCCCTTTTTTTTAAGTGGGTCGGATTTGAGATTTAACATACAGAAGAGAATAGGGAGAGACAAAGAGGGACAAGAGGGGAAAAATCTTCTTGGAAACAACCTCGTACCGAAATTACGGAAGTTTTTGCCTCACAGGATCCTTCAATATTGCGTGAGAAAGCTAAAAATCCAATAGTCATTTTTTTCTCCTTTTTTAAAAAAAGGTTTCCTCCCGCGTCAAAAATTGAAAGGATCGGATTTATTGTTACACGCCTGCCTCCTTTCTATTAACCTTGTTCTCGATCGCAACCTCTTTTCTACATTACGTGAAAAAATGCTATTTTTTTTCCTTGTTCAGATTCAATTTGAAAGGTGCTGTGGAAAAAGTTTTTTTTTTGCCCTGAAAAAATAATCGAAATTTCGCGTTTATACTGCTAAAAAATGACGACTCAAAATTTCAAGTAATTCTTTCGAAAAATCGATTTGAAATAGACAAAAATTTTCAATTTTTCATATCTGAAAACACACTTATTTCGATTTTCATTGTTTCCTTGGAAAAAATCTCACAAAAACGCAAATAATTAATTTCCCACTTAATCTGGACTACGATATCCAAGCTCCGCCTCCGCGTATTCCTTGTACGTGACAAACATGGCGGCCCAACACCAACTCAGACATTAAATGAGTGATACCGTACTCTCTCTGTTTTTTCTTTCATTTTTTCGGCGCCGAGAATTTTCAATTTTTGGTGGTTCGTTTGGCGGTATTTTTCGGATTATGGTCGGTTCACACACACACACCAGTTGGTGTTGCCGGTCGTCACCCGACTCGCGCCACACTCTTTGTCCGTGTACTGCTTTGCCATTTGTGCGCGCGAACCGCTGCCCGTCTATCTTATCATATCAGGCGCCTCGTTTTGTCGCTTTTTCTACATTTGCCCTTCCTAGGACAGGGGTACCTGCGGTCGGCTTTTCATCCCAGAGAAAATATGCTTAAAAATTCCGAAAAACCTCTATTTTTCGATTTTAGCATCGATTTTCGCCCAAACATAACCATTTTTCAGAATGAACGAAGAACAAATCGCCTATTGCCAGGGGTTTGGTATTACGAGGAAGACACTGCCTCGTGCTCTCCAGTCAGCGATCCGGAATATTTCGCAGTTTCTCAACTACAGAACGTCGATAGGCGTGCAAAATGTCACAGAGTCCGTGGAAGTACCGACGTCGGCAATAGCATGTCGCCGAGATTGTTGGTCGTCAAGGTATAAATTGCCTGTTTAGTCAAATCTACAGATTCCACAAATTTTCTCGATAGGCTGCAAAATTAAGGCACTGCGCGCCAACTCGCGAACACCTACAAGACACCGGTTGGCGGAGAAGAGCCAATTTTCGTGGTCACCGGACGCCTACGTGAACGAGGCGAAACGAGAGATCGACTGCGCCACCGAGCACTTAACACAGATCCGTGCGTCGAGAAGACATACACAAAGTAGGTGACCGTAGGCAGACGGTTCCTGAGCCGCCTTGCTGTTGTTCCGAGCCCATGCACCTGGACAGATCACGAGCTATAGTTCGTTAATTGTCGGACTCGTCGTCCGAAAGGAGCGACTATGAACAGGACACCCTGACACGTACATCATTACAAGCGCCGAGCCGAGAACGGAGGAGCCCGTTTTTAAGGTATTTTTGTTGGAGAGCATACATAGAGTTTTGGCGCAAAATTCTCATTCATGCTTTATAAACCAAAAACAGAGAAGTTTCTAGTTTCGGCTTAGGAACTACTGAGAATCGGCTTTTCCATGACATATATGTGTGGAGCTGAAAATCTACTTTTGACTGAAAAATTCAAGTTTATGACTAAGAAAAATTAGATAATTAGACCATGCTATTATTTCATAATATTGGTCCAATTTTTCTTGCTTTGCTGAGCAAATTAACAAATTTAACAATCGGCGGGGTTTCTGAAATATTTTTGTAAAAAAACCGATTTAAACTCCAATTTTCCAACCTTATTTTTACATATTAGTACTAGAAAAATTGTATAATGGGGAGAATTCATAAGTTCTAAAATCGGCTGTTTTGTAGCAAAGTTTGTAAATATATCATTCTTAAAGTCTCTAAACGTGATTCTAGAAAACGTGTCTCATCAGGATTTGATTTCTGCGACACACTTCTCTCGAGTTTTACATAGAAGTTGTTCATTACAAATTTCTATTTTTAAGGTCCCCATTACCATTGTCAATCTTTCATTCCGATTATTTGCCTCGTCATAGCCTGCAAGAAGGGGAGCCTAATGCCTAGACAGATGAGACAGAAACACATGTGTGTTTGTAAGTGTCTGGTGTGATATACCCAATTCGTTTCGGCCGTCTCTTGTTTTCTTCCTGACACCGAGTTTCGAGCGATTTTCGAGGTCGTACAGTTATGAATTGGCTGTCACTGCTGTGGCTAACAAACAAAAACAATCAAACTTGTGCGGAATTGATATTCTAAAGAGAATAAAGAGCAACCATGGGTGGCGACTAGCATCGGAAGTGCTTGTGACCTCTTGGTGTGAATTTTAAACGGTTTCCTTCCACAGACTCCGACATGCTAAAAATTCCAGCCGTCGGGAGCCGTTTAGGGTCTACACTGATAGATGATGATTAGAATCTTTTAATTTGGTAGAATTCCCCCCGCGGGACCGCTTAATGTTGCATGTCGTCTTCTTCTTCTTGGCAGCAAAATATCATTGATGATGAGTTATCTCAGTTTGATGCTCAATGACGCCGTGAAACAGCCACCCCACAGTAAATTAGTCGAATTACCGATGGGGCGCCCGGGTTTTTGGAAGAGTCATGCGATTGGGAGTCCACATACACACGCACCATCTCTTTCACTCCATCTAACAGTGTAGTAGGGTGATGAAAAGGGGGGGGATCGATGAAGAGACTCTATTAATTAAATGACCGGGGCGGGGGCCAAATTGCACATACGCTTGGTTTTATTGCACCGTTGGCTCAGTGAGAGCAACATTTTGTGGCAGCACCAGGGGTACTTCAAATACGGGACGAACAAAAGTCGTTGTTGTTTCTATAGGAAGGCTTCCGTTGGACTTTTGAAACCAGATCAGATTAGGGATATGTAATTGACGGTTTTGACCGTATGTGTCCATACACGCGTCGTTGTGTGGTGTGTGGCGACATAAATTAGCGTATGTGCTCCGCATGGCCTTTTTCCTCCTTCCTTACAATGGTAATTATCATCCCCCACTACTCTGGGTCGCCATGGACGAACTGTGAATGTGTTGACAGTGCGGGCCCGAAACTAGTACATGGACATCTTGCCCCGGTGCGGTGCGCTCATCGTTATTCCTCCCAATTTAGTTGTCCGTTTCAAATGTCTCCGGTACCCTATTGGACGAGACAAGGAGGTGATGGATTTGCAGGCGGGGAAGGAATTACATGATGTTTGGGAGATTATGGAAAGGTAGTTTCACCTCGTATTATATGGTTCTACAAAGACCAATTGTCTTTTTTGTTCGTGGCTCAAATGAATAATTGGTACGGAAATATAGAAAAATGTCCGACTAGGTAATAGAATTGTTTCTATGTTTTTAACCAAAAATAGCTCATACTAGTGCACTTGAGTGTTGAATTTTCAAAGGTTTTATTTTCAAATAGAGCATTTTCAATACTTATAAAATCAATTTTCGGTTCAAAAACTTCTAATTTTCTCACCGAAAAAGTTCTCACAAGACAGTGACAGAGGGGTGGTCGCGTGCGAGTCGTTTTGATATCCATCTCGATAATCAGAGAATGTGATCTATGCCTCAATGACACAGTTCCGCGAAGGAGTCCGAGAAAAACGTACAAAAGAAGAATATTGATAGAAATAACATTTATTCAAATCAAAGGATATTAAAAAAAAAGAACATAAACTATTTAACGAATTCACAAAAATTCGGAAGCATATTTCCTATAATGAAAACATCCTAAAAATTCTGAAAATGTGTACTGCACAACATTTTTACGCGCATAATCTCTTGTAGCAAAAACTACATTCGTAATTCATAAAATTGACTAATGTAGCGCTTGTTTAGAGTTATGTGCTCTACGAAATGAATTTATATACTTTATCGATGGAAAAATAATTTTAAGCAGAATATGAGAAAATAATATGAAGAAAAAAGAAATTCGAGTCACGTGCTCTGAGAAATGAATTTAAAAATTTTATCGCTGGAAAAATATTTTTAAGCAGAAGATGAGAAAATAATATGAAGAAACGAAACTTAAGCAATTCATTCGAGATTACGCGCTTAAACCCAGAGCTACAGTAATCTGTGAAAGAATTAGTGTAGTATTCGCTACTAGATATTAAGTGCGTCAAATATGTGCCTATGCGCAATAAACATTTAAGTTTGTGTTTCCGTAATATAAGTTTTTTGCGAGAACTACAAAAATATAACTATTTCTATTCCAGGTGACCGGCCTCCCACATAACGTCGAGGCTGCCGGCAAGGAGATCGAGACGCACATCTTCCGGCGAACCGGAAATCTTCCAGAAACCCGACAAAATGACTGTGCCGGACAGGTGGCCGGTGTCTCGTTGATGGTTCAGAAGCAGCACAGGCTCAACAACAAATGGTCCACGAGGCGGTGTCAGCAACAATCGATATCGAAGAGCATTCGGCAGTAATCCGTTCAATCAGAAGGAGATGTCGTCGCCGCCATTGGAATGGAGAGCTCGGGGATTGGACGCGTTGCTCGCAGCCATCGAGGCGTAGTTCGTTGACTCCGGACTCTTTCCGGTACTGGACTGTCTTCTCGTCCATCGTGGAGGACAATCGGCGAAAAAAGGTCTGCCAACCTACGACTACTGGGGAACCGACAACTCGCTTAATATTATGGAGAACGGTTAGCTTTTTTTTCAACGAATTCATTAATAAGAATTTTAAATGACAAATAAGGATTTTTCCGAAATTCCACTCAGCCGCAAGTACGATGCTCTGTACGCATGGTCGTCGATGGGATTGGAGAAACGCGAGGAATCCCCAACCAATGGTATTTTTGAAGGAATTTTATAAATTACATTTTGATATAAAACAAAAAATGCAATTTTCCTTCAAAGTTCCCGTAAATTTTTGAAAGAAAATTTGATTTTCCGCTAAAAAATTCAAGAAAAAAACAAGTTCGTGTTTTCCACTCGGAACCTGACGGCTTCTTATGTTTTAAATAAAAAATAACGTTTCTAAAACTCATAATGTTTAAAAAATTTCACAGTAAAAAATTATTTTCCCGAAATCTTGAGACCTATCCGTTTTTGAAAATAAAAATTTAGGAGTAAAATCGTAGTTTTCTATATAAAAATTATAATTTTCATTTGAAATTCAATCAAAAAATGTTTAAATAAAATTGGATTGTGTCCGTCGAAATCTATAAAAAGAAAATTTTTTTTGAACAATAAAAGACAACTTGTAATTTTCTTTTGAACTTCGAGGAAAAATATGTTTTTTTTCACCGTTATGCAAAAAATCGATTTTTTAATAACCTCGTTTTTGAAAAAGGTGAAATTCCAATTTCAAGAGGTAAAGTTAATTTATTTATTTTATGAGAAAAACTTGAAATTTAAAGGAAAATTACTGAAATTTACAATTTATCATACATATTTATTTCGACATATCTCGAAATATCAAGTGGTAAATTTTCTCCACAAAAGTGTGATTCTCTTTAAAAACTAGAAAATTTCAATTGTATCTGAAGCAAATCAAATTTTGCAGGCTCATGACCTCCCTCAAAGGAACATCCGCCGGCTTCGGCCTTCTCAGCAATCAGGTCTGGCGGAAACATGAATCTGTGGAGCCCAGGATCGTTGGCTGTTCAGTAACATCTGCCTCGCCGACGTCATCCCGAGACCTGCGATCACCACGATCATACTCTCTTGCCGATCAATGGATAAGCTGTGGATCCATTCATCAATCCATTACTATCGTCTCTCATCTAGCAAAAACCTCAACGGGTTCCAATCTTTCCATTCTTTAAAAGATTCTTTTTCCCATTTTCTACTTTGTTCATCGGTGTACAAGTCCCTCCATTCCCATTTTCTCACCTCTTTACTACATTACTATGCGAACACACAAAAAGTCACCATCATTCTCACAAAATACTAGACAAAAAAAACGAAAAAAATCACATATATTTATATATAACTATTATTATTTGTTATTCATATTTTTGAATTATCGATATTATATATATTTATATATGTAACCCATACTGTCCCCCAATACATATATTCCTACAGTAGGTTTTTTTGGCTGTAACTTTCTCTATTATTTTTTGCACTAAGGACGAACAACTCATGTTTTTAACAAAACGGCAATTATATATATTATGCCTCTTTTCTCTCTATCTCTCACCTAGTGTTTAGCTCCCAATTTTCCCCCTCTCTACTACGCAACTAACGGAGAATTGAGAGGCCTTTTATATTTACAGCATCTTTATAAAACTCGAGTGATCCCCACCCCATCAAATTTATCGTATGTAAACGTTCTGTCGATATATTACATGGTGTATGTGAATGAAGCGTTTCGTGTCGTCTCTCCATATCGACTCTGGTATCCATAGCAACTCCCCGAGCTTTTCGCTCACTCGCGCCCGCCATATACTATACCTTTACTATTATTAAATGCACTCAAATCCTATCCTCCGTCAATTAGCCGATCAATTGTCCGAATTGCCACAATGCTCCATTGCGGGTACTATTAGCACAATAGTTGAATATATTAATTCAAAAATATTTATAGTTTGGAGGTGTCCCATTGTTTCAGATATCCGCGCGACGATAAGTGCCACGTTGGGGGAAACGCCAAAGAAAACGAGTAGGGATTTGCCTAGGTATAGAGGCGACATTTATGGAAAATTTGAAATTTTCTGAAAAAAAAAGGATTTTTGTTCTTTTATCAAAAATGCCTTGTCTTTTCGCCAAAAAAATCAAAATTTTCGACTTAAAAACTTCAAAATTTTTTCAGGATCACACTATACAAAATACAAAATATCTCGTAGCAAAAACTACAGTAATTCTTTAAATGAGTCCTACTGTAGAGCTTGTGTCGATTTACGGGCTCAAGTTTAATATTAGATAAAAATGAGAAGAAAGGTAAAGACACGAAGAAACGAATGATGCCAAAGTGTAATATCGAAAATATTCGAAAATAAATAAATTTCAGAAATAGTCCGTAAATCGACACAAGAGCTTCAGTAGTCATTTAAAGAATTACTGTAGGTTTTCGTTACAAGATATTTTGGTCAAATATATCGTATGTGCAATATGCATTTATTTTGTGTTTCCGGAATAGGTAAAATGTCAGAAAATCAAGGATGGAACCCCGCGTTCTACGGGTATTATGGCCACGGCCACTTTTTCCAAAACTGCAGTGAAAAAGGCGTTGTTATTTCATTTTCTGAAAAAAACATTGAACATTATTATCGAGAATACGATCTGACAAATTTCTCATAATTTATTTTTGATTGTCGCTACCTGTTTAACTTTACTCCGCCCCCAATCTTGTTGCCGGAAGTTTGATATTTTGTTTGTAGCTGTCTTGTCGAAGGACGGGGAGGAGGTCAACAAGGTAGATAAAAAATATATTATGCGAATTTTGTGCGATCGTATTTTTTCGATTATATATATATATATATCTTCATGTAATTCTCATGAAATCTTGAAAAAAAACGCGACACATGGAATTACCCGTTACTCGAGGCCCACTGTTTTATAGTTTGAGCGCGTTGCAATTTTTTGTCGATAACATAGTTTCTATTTAAACAAAAAACATCGTGCGCCCACATTGAAGAAAATGCTACAATTGGTGGCATTAACTTTCTGAAACAAGGATTTACAGAAAGTGTCAGGGCACCATAGCATGATTGGATTGGCTCGAGCAGAATGGATATCCAATATCATCTCAAGTCTTGATAACAAATGTCTGGAAACATGGAGAGTGCAGAAAAACATCATACATGGAAGATGCGGAAAAAATCGATAATCTATTGCGAAGTTAGCTGAAAATCGATATTCGCGATGGCACCGGTGACGAATTTGAACGAAAATCGATAAAATCGATTGGCGCGGGTTCCCGCCGGTTTTCAAAAATTAATAAAACATGGTCGATAAACGAGCACCGTTGAAAATTACACCGTTTAGTGATGAGGAATATCGAAAAACGTCGATGCAGAAACGGATGGAAATGGAGAGGGAACGAGTGAGTTGCGTTAAATAATTTTTTTTTAAAATATTTAACTAAAGGCGACAAGGCGATTTTTAAAAATCGATGTTTAGCGACTTTTATTCAAAAGAATAATTTCAATGCCCTAAATCACTCAAATGGTGATTAAAAAAGTATTTGCGCGCGCGCGTAAAATTGTGCATGCAGCGTATGACCCTATGTGGTAAACCTCCGGGTCCGACACTTTTTGGTGAGGGTTTCGCATCGCTATAAAGATTGCAGATCGCGGCGTGAGCGTTGGCGGCGTTCCGACTTGCATGAGAGTCCTTTCCTACTTTTGCAAAAGAATCGATCGCTCGGATTTTTCAGCTCGCACGTCTATCCAACCAGGCAGGACGAATCCGACGATATCCTCATCGTCTTCCTCCGACTCTTCCATAACGTCATCCGCGTCGTCATCTTCCGAGGAGAAGTTGACTTTTCAATTCGAATATCTTGGGGAAACCCACAGCAGCTGGCGCGGAGAAAATGATAGAACTCAGCCAAATTCCCAACGCATGGGGTCCGTCAAAATCCGCGTTAGTCACTACGTGGCCGTAAGCACTTCTGACCCACTTCCGGCGATTTTCAACGCACATCTTCCGCCGCTCTCCATGGGACGACCACCGCTGACAAAAAGCGCGAAAAGTCGGGAAATCGACGCCATTTTCGGCTCGGATAACGTGGATTATAGAGCGGGGATTTCGAGCAGGATGGCCGTGGCGAAGAAAAAGTCTATGCTCCCTATGGAGAAAAAGAAGGAGGAAGCGAAACCCTCAGAACAGGAGCTAGTGGAGCCGTTGGTCTTTGACTGCCTTATCAGAAGGTAACTTTGTACTTGCACCCTGCAAAAATTCCGAAAAATTATGCACGTGGTCACTGCTAGGTTTTGCATAAGCGAAGCAAAAGCGCCTCATTGAGAATACACGTTTGCGCCAACTCTCGCTATCCATTGGCGTGAGAGACACATATACTACTTTTTCCTCTGAACGTGAAAAACGAAAAGAATACCCGTTTTGCCGTCTGCATCTCTTCTTCCACACGCTATTTTAGCCGTCGAGGACGAGGAACTCTTCCAGGATTTTCTTGGCTTCTCATATTCGTTGTCAAGTTTTGCCTCGTCCGCGAGAAAACGTGAATTTTGAGACGGCCAGCGAGCACGTGATTCTGCAACTCTCCTAAAAATCGATTGTTCCTGTAGCTTATAATCTTTTAGAGGCGCATATTCCGCTTGCGGAGCAAAAGTAAACAAAAAACATGCCGGTCTAGATACAAATCGAAGAATTTCCTGCAAAATCAATAATAAAAAATTTTCAGGCGAATCGATCGGCTTGAAGACTTCGACACCGGTCAACTGTCCGGAGGATCCGATTATTGTTTTTAAAATTTTTTTCTTTTAAAAAATTTCCCGCCTTTGCAATAAATAAATTCTCACCTAGGCTAGAATTTCACTATTCAACTTGAAAAAATATGGTTCGCCCAAACTACGATAAACAAATGTGTGTCGAGCGGGCGAAGCCACTGAGAAAGGAGCAAAATGTACACAAAACCATATTTGAGTGTAATTTTTTCAGAGTTTGGCGCCGATTTTCTGTGAGACATGAGTTTTCTCAATTTATATTTGGTTATTTTTATTTTAGTTCTTACTGGTAAATGTCTGGGTAAGTCCTGATGACTTGTGAAAACGAAAAAAACTCTTTCATTGATGCTAGTGCGATTGCTAGGAAAGCAACTTTCATTCAGTTACCAAGAAAAAGTCCCCATATGGATCTGCGTGGCATAACAACTATCCATCCACGGAGATGCAAATCCGATCTATTGGCAAATAACATGGAAGAGTATAATTTCTCTTCCAAACACGGAAACCTTCCCCTTGGCGGTAGTGCCCACAACCCTGCATGTTTACCAAACTACACAGACAGCGCTTGTCTGCAAGTGGCAAAAAATGGCCGGCGAAATTTTTATGTAAATAATTTTCAAAGTGTTACCCTATTTGCACCTTTTTGGCAAAATTTCCATAAGTAAGAAATTTGATGGAAGAAACGATGAGAGGTTATGCGGGGAGTCTGAAAACGGGGCTGCATGACCTGTATGCGACCTGTTTAGGCCTAAAGCTAGTGACCCCTAGAAATCAAAGTTTCAAAGAGACTTTATTTTTCAGCACTCCAACAAGCTCAAGGCAGAAACTCAACGGTACGACGGATACAACAAGCTGGCGAACAGTGACTGGGCTTCTGCTGGTAGGTTTTTTTGGAAGAGAAATGACGTCACACTGCCCTACTTCTTCAGGAAGTCGGCTGCATGATGCACGCGGTTCCTACTACTCAGACGGCGCGTATATTCAGTGAATAACTCAGTCCTCCTGTCTCCGATATACTATTGGTTTAAAGGAGAGTCCGGTATTCCTTATACAAGAGGATGCCCCACTTGTTATTGGCATTTTTCAGTTTGTATTTTTTTAATACTAGTAGCTGAGCCATTTGTAGGTCATCAAGTAGTTGCTTAATAATGCAATCAAATGGAGTATCCTGTCCACTAGAGACACTTAAAATTCAAGATACCCCTATGTGATAATGTATTTGAAAATGCGAGTACTGGGGAAAACTACAATCCCATTTTACCATAGTGCAGACAAAGCAACTGGAAATTTTACCTCGAGAACAAACCGTCAATGAACGGACTTCATGGATTGATGGATCATTCATCTATGGTACCGCCCAGTCATGGGGGTCTAAGTTTTAGGACGGTTAGCTCAGGGTGCACCTGGATATCGACCACTTAACAACCCACATATTCCATTGAATATCCCCGCTCTGCCACAAGTACATCGATTGATCAGAGTCCTAAGATAGATTATTTAGTGTGTTCATTGTTCTATAGAAAAGCTATAAATAATTTGTAAAATTGAAGTGTTGGGAGACTCGCGTGTGAATGCAACAGCATCCTGGTCTTCTTTCATTTGGTCTGATCCTCTTCCGTGATTGGCATAACTACGATGCAAATCAAATCTATCGAGAACATCCTGACTGGACAGACGAGCAAATAGGCAGCACGGCGCTGGGATTGGTCATCTATGCAGAAGATTATTTGCTTTGTTCCAGGACCTCTAGGTTACTCATAGTGCATCATCTAATAGCTTAAACTCAGTGATTTCTGTTAAGGTGAAGTCGTTCGTTTGTCAAACTACACCAAAGGAATACATGCCACACATGCCACCTGGAATCTCGCTTTTGGAACACCGCCTTCAGGTTCCCTCACTCAATTGTGCCACCAGCAATAGTGGCTGCTGAGAAAACGAGTAAATAAATGTGAACCGGACGGAAGATGGTGGATATCCTGCATTGAGTGCCAGCGAATTGGTGGTGGAATGCACAGGATATTGGGAAGGAGTAGACAGTGTGGATGAAAACCTTATTCCTGGTTAGTTAATACTTGAGTGGTTATACTTTTGATAAAGATTGTTCAGGATGGCAAGCCAGATAGCTGAATGAGAAGATAACATAGTCGCAGATCTTCGTGATTACAGGACCAATGCATTTCTCTCGTTTGGATGTTGTTGCTTCATCAATAATGAGAGGAAGGGACAATGGAGTACCCCCGTATAATGAATTGAGAAGAACCTTCGGACCTGCACCAAAGGCATGGGAGACAATGAATGAAGATTTCTACAAGAAGCATACTGCGTGGAAAAGTTGAAAGAGTTTTGTGGATGGAGGCAATATTGAAACTTATTATATCTGGATGCTTATGTTGGAGGGCAAGGGTCTTTTATAAAAGTTAGAGAGATCCTCCAATATACCCTCATAACATATTGTATAAGTTTAATTCATCAATAATTCAGCTTGGACCATTTAGAATGCTGGAAGGAGGTGAAAATGGCCCTGAGATGTTCAAAGAAATCATAAAGGATGTTGGCGCACCCGTATTCGAGATGGAGGAGATCGATTCTGGTTTGAGAATAAACTAAATAGATTATTCACTAAGAAGTTCAAATGAAAGTTCATAGTATTACACTTCGTATATTATCAAAGCATTGCACAACCGATGTCGACGATGCTTCAGAAGGATGTGAGTTATAGTAAAACACCCGTTGGTTATGATCGCGTAGTTAATAGAATGTTTCATTCCAGTCATGGATCTTGAAATTTTGTCATGATTCTGTTATATAACAATATATGTATGTATTATATAATACTCATGTCTCAATATGGCATTTAATTTCCAGGTATTTTTCTTCAAAGAAGGTGATCCACGCCCCCGGCTTCCTAGTGAATACCATTGGACTTGAGTGCTCCCCAAGACTTATTCAATTCACCTACTGGGATGATAACGAGACTACTTATATCTACAGTCTAGGTTTGGCGTATATTCCTTTTAGTCAGTCTTTATTTCAATCTGATATATACTACCGATAGAGACTCAGCGATTATAGAGTTGATCAAGCTAAGAACTTTCAGTTTGCTATAATATCTCGCGATCATAATATGGTTGAACGACGTATCCGAATAGGTCATAACAGTGCTTGTGACAGCTTGACTACTGACTTGTCAACACAAAGTCCCAAAGTTAATGTCTACAAAGTGAATGGTATTTTTTCATACTTGATTTTGATTTAAATTATGTCGTGAATCTGCAGCTTTGGAATGGCTTCAAAGTACATACGGTCAGCAAGTTCGGATAGAAAGCGAATACCACTTGACAGTGTGCACAAGAAGGTTGTGCGGAATCCTTCGAAAAAAGGCTTCGTTTTGGAACTGGACAAAAGATTGAGGTATGCCACTCTATACCGAATCCATCAGCAATGCACGGACCATTTGTATTTTGTCTCAAAAGAATAATCTTCATTTGGTGATAAGATTGTCGTCTGATAGAGATTTTTCTAAATTTCTGATCACATTAGACAGGGGCTAGTGGAATGCAGGGGTTATCATAAAGGCTGACGAGACTTCTGTGAGTTTACTTCAAGAAATACGTCGAATCTGGAAATTATTTCAGATTCTCTTGTCCCAAGCAATCACAATAGAACACCGGCAAGACCGACTGTACCTGTTCTTCCGTGAAGCCTACGCAAAAGCATTCAATGATAGTGAACTTGCCAAGATTTGACTCGGAAACTTCATCTTTGGCTCATCGATGATGATTTAGTAAATGAGACAATATCTCGTCAGGAATTGGCAAGTGCAATGGGAATGAAAGCATAAATAATAAATACTTGAGTTTGTTGTGTGAACAGAATGTTCGCGATTGCAAAATAATTAGGATTCGCTCAGTTTCAATGAGTTTTTGACAGTATTCTTGATGGAGTTTTTTAATGGTGGGTTTATTGTGATTTACTAAAGTTCTGATCACAAATACTACACGTGAGTTCCAGTCTGTTTACACTAGGTTCGGTAAATATGTATAATGTTATAGGGTGACTGTTACTGAAGCGCCTTAGTAGTCTTCTCTTCTTTGAATGGCAACAAACAGGCTCCGTCATTAACACATTTAAGCTGCATTTCTCTGCTAAAAGTAACGGCTTAATCGAAGTGCGATTTAAACATTCGGGTCTATAATCGTCTTTTAGTATATTGTCGCGCCTACTAAGGCTCGCTTTAATAATCAGTTTTAAACGCGAATTTGATGGTGTTAAATACGATTTTAATTTGGGAATTGTTCACAATTAGATGCTATCTTGACTAATAATAAATAAATACAGACACAAAAACCTTTTACTACATGGACAAAAATCATCCGAATCTACCCAAATCGGCATTAGGTTAATGTCTTTGATTAATCACCTTCTTTAATTTGCAGCTCCTCAAAAGCAAAAACTGCACAGTCTATTCAAAATGAGTGATTTGGAGGGAAAGAACAAGGTTCTCCGAATGGATCTCGCAGAACTGGTCAAGTCCCTCAATCATACCGCCGGAGTTCACATTACCTAGAAAGTGTGCAGCTTCGATTAACTTTCAATGACGTGCTGCACAGGTGCAGGTATACATCCCTGTGTAGTATGCCAAGTATTAAGTTTCAGGAGTAAGTTCTCGACGATGCGGAGTACTTGACTTGTAATAATTTCGACGCATTGTTCTCGACGGAGATCTCTGACGTCCCGATCGGTCTGGTCCATTTAATAGATTATTACTCACATTTATCAAGTAGTATGGTGTTGAATTCAAATTCGCAAGTAAATACAACTTCAGGCCATCATGCCACACCTCATTCCCAATAGTGACCGCTCTACTCCTGCTCCACTTTCTCTGATTCAGAGAATTTGTGCATTCAAAGACTGGAAACCTATTCGACTACACGTCTTCATCATCGTCTGCTTTGTCGCCATTCACATTGTCCTTTTTTTCGAACTTTTCTGGCGTTTACTGTTTAGTTCGGTTTTCAAAAGCAATCAATTAAGATTCCTCCCTAAACGAAGATCTAGACCTCGGTCGGGTGTGGGTGCCGGGATCGCTATCACTCTCTCTTCTATTGCGGGAGCCTTGTCATTTAGCATGGCGTTGATATTGCGCTTACAGTGAAATATTATAACACTGCTTCGAGAGAGACAGTATTGCGCAGTATATTCCATTTGACTCGGCTTCGCGTTCCATAAGGTAAGAGCCTCTCTCTTGGCCTAGCGCTGTAGGTTAATTAAAACAATTACTCCAACTCGTAATTTCAGAGCGTCGCATTATTCACCCTATTCTTGTCTACCCTTCACACCATCGGCCATTGTGTAAACTTTTATGACGTTGGAACTCAAAGCGACCGTGGACTTGCTTTTCTCTTCCAGGAACAGCAACATTTTACGGGTAGCCGCACCTACACGACTCGGTTGGCAGATCTCTCAGTAGATTGAACGTTGGCTTGCTTTCAGCTCTGACGTCGCGCCTACCCTAAGCTGGTTCTATGGAACAATTACTGGGTTGGCGGGAATGGGATTAGTTATTATTTGGTTATGAGTATCATTTATGTGTTCGCATGGCCAAAGATCACTAAGCATATCACTCGTTTTCTCCGGCTGACTCATCTTGTGAATGTTGGGTTTTATGCACTCACGATCTTCACGGACTTCCTTTTTGGGGTAAGGCTTAATTTAATTTGATTCATTGCGCCTACGCTCTTTTTACGCTCTTGACGTCAATATTTGGTACGTCTCCCAAATTTGGCACGTTGGGACTCATTGTCCTTTCTGTAATCGAACGTATAATTGGGTTGATGCAATAACCCATTACAAGTCGTTTGATATAGCCCATGGAGAAATCCATCAGATATTATATACATCGAGTACCGTCGTGGCCAGGAGAATTTGAATATAAATCAGGACAATGGATTACAGTATCACCACCCTCTATATCATGTACCTTTAATGAATCTCACGCATTCTCGATTGTCGCCTCAATTCCACAGGATGAGAATATGAGGTTGTATATAAAAGCAGTTGGACCTTATCCCCCGGACATGGAAGTAGAGAAGTGGATTGATAAGCTCTTGAATACAGGGTCACCATTCCCATTGGTAATTCAGATGAAAGGACCATATGGTGACGGTAATCAGGAATAGATGAATTATGAAGTTGCAATAATGGTTGGAGCAGGAATCGGAGTGAGTCCATATGCATCCACGCTTGTTAGTACCAAACACATCAAGTGACTCGTTACAGAGTGATCGATGTCGTAAATATTTCCTGTGTGTTCGAGTCACAAGAACTTTGAATGGTTTGTGGAAATGCTGTCCTGAAAAATGACTATTGAGAATCATTTTAGCAAAGCCTCCTGGGCCCGAGACACACATTATTCGTCACTCAGATGTTCCATAAGTTTTATTTAAGCGGAACTACTATGCTTGAGTTTTTTATGCGTTTTTGGTTTTTACATGTATAACTCGGCTAAACCTAATGGAGAAAAAGGTTCCTTAACTAATAAAATGTTGCTCAGCTAACTATTTCTATGCAATAAAATATGTTTCAAAGTATCATCTCACAAGTCCAAATTTGATTATTTTTCTTAAACCGAGTATATTTCAAGTCCGAAATCTAGTTTTCTTGAAAAAATTTGGTATATTTTTTGCACATAATCATTTTATAAAGTGCTCTGCAAATCAGAAATAGTTCGAACAGTCTTTCATAGTTAGTGTGACATTTATTGGAACTTAAAAGAAAAAATTACGCGACATAGAAACGCTCGATTATCTGAAAAACCAATGGATTTTGATTCTAGTTAATTTATTTTCAAAAACCGATATAAACATATTTTGTGATAATTGTAAACTAAAAACTATACCTGAATATTTTTATATTTATGTGGTTTTTGATTTCAGGATTCAATGGTAAAATACTACCCTAACGGCTTACCCAAGTCTCAGAAAATTGTAGTTACTCTCAACAAATTAATACATATCATTTCTTATATGAAGTACGTTTGCGAGAAGCACTTCCGTGCCACCAACACAGGCATATCAATGTTCACTGGCCTACACGGTAAGAATCAATTCGGACGGCCCTTCAAAACTTTCTTCCAATGATTTATTCAGAGTGAGATAAGGAGGTTAGTTTCATGGTTTTAACCTCTAAATAAAGCAAATTTGCAGCAATCCGAAATTGGAGTGTTCAGTTGTGGACCTGTATACTTAAATGACAGTATAGCTGAAGGATGTGCATGCCAATCGACAACGAGATGCTCCATTTGCACTTTGAACCTTTCTAATCTTCCCTGTTAGATTTACTATGACAAAAAAAAGATCATGAATGACAAAACATAGAAAAAAAACCTGAAATAAAGATTTCACATTTGTCCAGGTAGTATATATCCCCAATACAAACATTTTGATACGGTCTCGAAACTTCCCCATTCCCAAATAATCATCAGACATTGTAATTAGGCAAAAAACCAGACCCCTCGGCTCCTCCCTCACCACAAATAAAAGCAATTCCCCCATTTCCCCCCAGTTCATTCACCAACAATGAGTTTATGACGTTCGTGTCATACACTTCGTTTTCTTTACGTGTTCATTTCTCCGTTCTCTTCCTTCTCGTCGCTTTTATTGTGATCTATGACATTTTCGATGAAATTCGAGAATTTCAAGAAGTAATCGAAAAAGATGCCAGGAAGTTTGAGGTAAGGCAATATGTGGTGCAGCAATAATATCCGCATTTTTCGTAGATCATACCGTTATGGGACAGTCTGACACCACGTGATAAAATAGTATACGAATGTAAAGCAAGGTTGAAACGAAAATGAAATTTCGTTTTCGAAAACGAAAACTTTTCGTTTTAAACGCGAAAGACTTAGAAAACGAAAACGAAAATATCAGTTTTGTCCTATTTAATTGGTAAAATATAGTTTTAGGTACATGAATTATTAGGTCCATTTTCGAATCAATAATAAACAAACAATAGTTTTATTACAAACAGTAAAAATAAAATAAAGCTAAAGAACAATAACAATCACACTTGCTGAACAACTCTTCCATTTATCCAAATTTAAAGCCACTTTTTGATTTAGCGTAAGAACACAGACTTGCTCAACGACTCTACGTAGACTTATTCCAGCTTTGTAGAAACGTGAGCCGCCAGCTCCTGAGAAAACTCGTTCCGATTCAGCAGATGAAGCTGGGGTTGTCAGATATCTGTTCGCTATATGAGAAAGCAATGGCAACTTAGATCGATTGAGCGTATTTTGAAAAAAGAGCGGGGTCTGATTTTCTATTGTTGTGGGTATCGGAGAAAACCAACTTCGGCACTAGCACCGAGCATGGAATCTACAGGCGCTTTGTATTCTTTTTCTGATCTTGGAATGCTTTTTCTCGTAAGCTTCAAACAGGAACTTCGTTATTCCCACTAGAGTTTCATTTTCTGGCTCATCGACTGCTTCTTCTCTTCTTTTAATAATCCTTGCGCTAAGCTCAAAACGACCAAGCTCTTTTCCGTCTATTTTCTTTTGTATCGTGGGTCCCAATGTTTGATGCAACAATCACCAGTTTGAATGTCACCAGTCGGTGCCCGCGTCGTAGGTGCGGTCAATGGCTGGTATGTATATAATATATATTAGATGGAAACTATAACATTGAAAAAAAAAAGCAAACATTGAAACACAATAGAAAATCAAAATATGGGCTCTTCTTGAATAAAAATCAGAATTACGAATTGTTCACTGGGGCTTATTTCTTGTACAAAATAATGATTTTGACCAGGCTCAAAAAAAATACGTTGTGCACAGAGAGAGGTGATGTTCCTTTTTTCGAAAATTCGAAAACGAAAACGAACAAAACATGACAGAAACCCGAAAATAACGAACAAACGAAAATTCGAAAACGACAAAGTGACAAGCCATTCCTGATTACAAGGTCGGTATTTCATAAATATTGTAGAGAAAGGTTGCTACTAGCGATGATTCCAAAAAAATTTAGATTCATCAGAGATGTACACCCAAATACCCAAGGCATCGGCCCTAATTATTGATTAGACACAACCGCGCTTCTTACTTCCAACAAGCTTTTCCTATTTTTCCGGTTCTACTTCACCGCCGCCTCACGTTCAATTGCCGGTTTCGACAAGCGGAGCCGATTCGGAGGAGCTGTTTCTTTTTAGTTGTATATACATCTTTTTAAAATTAAAAAGTCAGTGTTGTTGTTACCCATAAAACAGTGAATGAAAAAAAAAGAAGTCTAGACAGATCAAATGTAAAACTGGCACAGAATACTCAAAGAAGCATAAAAAATGTATTTTAATAATGGATGATATAGGGAAGGTTAGAACGTTTCAAAGCGTGTGGTGCAAATGAAAGAGCATCTCGTTGTCGGTTGGCAACTGCACATCCTTCAGCTATACTTTCTTACACGTCGACAACTGAACACTGGCCCGATTTTGGATTGCTGCACATTTGCTTTATTTCGAGGTTAAAAAGCATTTAACTAATCTCCTTATGTTCACTCTGAATAAATTGGAAGAAAGCTTTGAAGTTGGGCCGTCCGAAATGGTTATTAGCGTGAATACCAGTAAACATTGAAATTCCTGAGTTGGTGGCACGGAAGTGCTAACCTCTGGACGAATGTACTGCAAGTAAGAGGTTCAAAAGTTTAACAGCTTCAGACCTCCCGCTGATGCCACTACGTTTAAATGCGTCCGCTTTAATCAGTTTATAACCATAACCTGACGTTTGATTTTGAGAATTATCTTCAATAAACTCACAAGCATAGTAGTTCTCAAATCACTTGTGGACCGTCTGATTGACAAAGATATGTGTCTGCCATAGTTCCCGACCTTTCGTGGTCTCACGTTCTTTGAGCACATCCCCCCACAATCCAAGGTTTGCATAGTCCTTGTGAGCTTTCGAGTCCACACCCATAGGAAATATACTTTACGGCCACGTACTCTGTGAAATGAGTCACTTGATGTTCGTTGTACAGATCAACAACGATGCATATGGAGTCACTCCGATTCCTGCTTCAACCATTATTGCAACTTCATAATCCATCCATTCTAGGTTACCATCACCATATGGTCCTTTCTTATGGATTAATGGAAATGGCGATCCTGTGTTCAATTATCTTATCAATTCGCTTCTCAACTTCCATGTCGATGGTCCAACTGCTTTTATATACAACTTCATATCATCCTGTGGACTTGAGTGGGCAATCGCCAGAATGCGTGAGCTTTAAAGGTATTTGCCGTGATATTTATGGTGATATAGGGATACAGTATGACCCATTGTCCTGATTTATATTTAAACTCTCTTGGACGACGGTACTATTCATATCAAATATCTCATGGAAGGATTTCTGCGTTTACAATTTCTAAGTTTTTGTAATATTGCATCAAACCAATTATGCGATCGATTACAAATAAAACGATTGAGAGGGACGAACACCCACGTAGTAGCAAATTTGGGAGACTGCAGTTGTCAACAAATATTCGAAGAAACTTCTTGAACTGAACAGTGGCAAAACATCCAACAACTTTGGAAGCCCATGAAGAAGAGTACGTGCGTAAAAGGCAATATTGAAGATGTGATCCCTTCAGAACCGGAATGCGTGATAAGCTCTCTTAATGAGACATGGGAACGCGAGATCATAAATGATGCACATGACAGCGACCAATGCAATTCCTGTCAGACCTGTAATTGTGCTGAAGAACCAGTAAATGATTGAAGGAAGGAAGTTGGATCTGAAAGTTATTTGATGAAAGTTGTTGTCAGTCTTGAGAGAGTTTGTTAATGCGTATTCTAGTAAGATTGAATGCAAAAATGAATTCAAGTAAAGTATTACCCAAAGAATGCTTCCTGAAAGAGACAAGCAAGACCTTGGGCTTGACTTTGAGTTCCAACGTGATAGAGATTGACACAATGTCCAACGGTGTGAAGAGTAGCCCAGAAAGCCGCGAAAGAGCGCAACGATCTAGAAATGTTCAGTTATTATAGAGTTTTTGATACTGGCGGTCATAATAAACAATACTTTGTCCAAATAGTATTTCCCATTGTTTAATGTCATAGTTTATTAGGTGTATATTCAAAAATCTGCCACCATCCTTCAGAACACTTATGTAAAGTCGACTTAAAAACATCTGAGTTTTTTGAGCAACAAGAGACCCACACTCGTTCTAAATAGAAATATATCTGGAGCACAGGAAAATCTTTAAACTTAGGAGACACTTTTTTAGTAAACAGAACACTACACACAAGCAACACTGATGTAATGTTACCTTATCCTCACTTCTATTCATCATTTATTTTGCCTTTTAGACATCGATTTTTGTGTTTTGCTTCTTCTCCAATGTAGCCATTATTTTTTTTCTCATCCCTTTTTATTTTTGTTCCATTTTTATTTATGTAACGTATGGTTTGTATATTTTAATGTGAGTTTTTTTTCCGTAGCTCACGATATCTTACTATCGTAATAAATTTAAAAAAATTTTATCAAACACTTACGAAGTTTAGGCCGCTATATCATAAGTTCAAACATCTGGCTGAGACACCATGTTCGATGAAAAGATCTTTCCTTTCAGGCGTTGTATTCTATTTTAAAAAGTCTTTTCAAAACATTGTGTACGTACAGTACAGATATCCTACTTGCATGAAACCTCCGCATTACTGTACAGATAATAAAATAACACGTTTTCCCTTATATCTGAACATGCTAAATATTTTTAAAAACAACTGCTCATTTGACGGATAAAATTTACTAATGCCATCCAAGAATAATATTTAAAAAACATGTGTTACACGCTGCCCTAACGTTTCTCACCTTGTGGTTCCAACGCAATAGCCGCAAATAGTCTGGAAAATGGAAAATACTGCGTACAATGACTGTCTCTCGAAGCAGTGTGATTATGTTTCCTACAAACTGTCAGCAATATCAACGCCATGCATTATGAAATGGCTCCCGCGGCACCACGAGTAATAGCGATTCCAGCTCCCATTACTCGTCGGTGATCCATGCGCCATGTATAATCTGAAAACTAAATTAACATGAGCTCCCCATTATATGAACACGCCAAAACCGTTCGAAGAAAAGAACAAGATTGATGGCAACAAAGCAGAAGACAATGACAAACGTGTGCGATAGGTCTCCAAGAACGCTGAAACCTTGTGGATCAAAGTTAGCGGTGCTGAACTGTTGAGGTGCCGGATCGATCCACGACGGCAAATGAGTTCAGAGAAGATGTTCTAAAAGTTATAATTGTTATACGGTAAGAGGCCTCCTGAATACTCACTCTCCAATACTTGGCTGATAGACATGTTCTCTCGATTGAACGTCAGTCCAACTTGCTTGTCAGGTATATCCGAGAAAGCAATCCGAGCAGAAATCATCGTAAGTCAGGTACCGGTTGGCATCATTGCTCACTCCTGCATAGTTCAGCACTTCATTGAATAATCGGGATGAAGCTGCACACATTCAGTAATGACTCCAGCGGCGACTTTGATTGTGGGACCTGACGAGTTCCGCGAGAACCTTTCGGAGTACCTTGTTCTTTCCCTCCAACACACATTTTGACTAGAGTTTTTTTGCTCTTGAGATCTGAAAATTAAAGTAGGTGGTGCATAACATTTTTTAAAGGCAGTTTTGGTTTTTCTAATGTTCATTAAAAGAAAATCTACAATTGACTAATTTCTCGACACTTCGGTGCCATATTAGTTTTGACCTCCCTGTCACACGAGAACTTTCTACAGTGCTCTCGCAAATACTATCGGGCTCCCCCGAATAAATTCAGATTCATAAAGAATAAATAACCTTTAGAACTTTACTATGTGCTCTCGAAATATTGCCGACCATAGGACACCGAGTTTCCCGGCTAATGAACCAACAATGTTAATCCAGCGGTCGCTAACCGCCTAGTCCGTTTCAAGTATCTGGAAATAAATTTCTTTTGGAGACTTCGGCGTTCTCTTGTTGTAACCAAGGTCTAACCTTTTATATGTAGTTTTGTACGTACAAAATCAAAGACAGTTCAAAACAACTTTACCGCTACTGCTGTTACACGTAATTAAGCTGTATTAAGTATATATTCAATTAGAACTTGCAAAGTTAATGGGAAACACGTCATGCCGGAACATTCTAAAACGTAGTCTTTGTATCACGACAAATTTATGCTGAAATAGTCACCATTACTCTCTCAAGACTGTCCCCCAATTGCATTGAAACTGAGCCACGGCTCATTATGTTTTTGCTGCATTGGTCATCGCGAACATTCCCTTCTCAAACTCATTATTCGCTTTCATTCCCAACTTGCCAGTTCCTCGCGAGATATTGTCTTAATATATCATCATTTTCCGTGATGAGTCAAATGAAGGTTCCAAATCTTGAAGTGCACTATCATTGAATTCTTCCCATTTGCGTAGGCTTTCGCGCACGGATGAACAGGACCAGTCGGTTGACGGCGTTTCTTTTGTGATTGCTTGGGATAAGAGATTCTGAAATAATTTCGAGACTTCAACGTATTTCTTGAAGTAAACTGACAGAATTCTCGTCATTCTTTAATGACCTCTGCATTGATTCCACTAGCCGCCTGTCTAATTTGATCCAAAAATATAGATAAATCTCTTGCTATCAGACGACAATCTTATGACCAAAGCACTGATGATTATTCGAGACAGAAGTACAAATAGTCCGTGCATTGCTGATGGATTCGGCACAGTGTGGAATGTAACTGAATCTTCTGTCCAGTAAAACGAATTTTTCGGATTACACCGCGTGGCTTCTTAACTGCCAAGGTGGTGTTTTCTATTCGGCTCTATCCTGACATGTCGTATATACTCTTCTTGAAGCCATTCCAAAGCATTTACACCATAAATATCTCCCTTCGCGCCACAATCATCATAGTTTTGCAAAGTAGTTAGGCTGTCACAAGCACTGTTGTGGCCAATAGCAATGCGTCGATTAACCAAGTATCGGCCAATTCCATAGCAAACTGAAAGCATTTTGGTTTGTATGGAACTAGATGGAATAGCTCACTTAATGGCACAATGCTAATCCAATTAGGGCGAAAACGTAAGTGGTGATCAGTCCAATAAGTTGATTGCATAAATGGCACACATGGTTCAAGTCCAGTTGTCTGTTCACTTGGAATGGTTGCGGGGGTAACCTTCCTTGAAGAAGTATAGCTGGAGTGATAAATAAATTGCAATGCGGAATTCAAAAGAACATAATAATAAACCATTAAATTTGGAAAGTACTATTACTTACATCCTTCTTAATGTCTCATCGATATTGGTGGTTGCTTTGATAATATCTCGAAGTGAAATACTATGAATTATTTGAACGGATTCTTCATCAGTGAGTATTATTCTCAAACCTTTAGAATCTATCTCCATCACGAATAGGGGTCAATTGATCCTTTATGATTCTTTGAACAACTCTCCAGGCCCTATTTTCACCTCCTTCCAGCATTCTAAAATAATGACGTTTTATTGATTCACGTAATCCAATATATGTGCACTGAGAAAGAAACAAGTATGCGTAATTTATTCTGCCTGATTTGCAAAACATACTACCTTGCATGGGTAACTGAAAGAATTAAGGAATTGCTATACTATAAAACTGAGGTGACATACAACGTCCCGCTGAGAGTCTAGCCTGCTACAAATTATAGAGTATGACCTAAAGAAGCCGTTAGAAGTTACTCGTGAGAACTTTTTAACCCTTGAGAAGACTTTAGCGAATTCTATTCAATCCACTTATACCAATCAGTTATAAACGAATTGATTTTCATTGTTTTTGCTTGAAACTCTTCGAATTCACCGCATTTTAAGTTACGAATTCTACTTTAAATCCAAAACTAACCCTCCTAATAAGCATCCAAATATAAAATAGTGCCTCCATGCAACTCTTCGTTCAACTTCTCCACCTTTGCAGTATGCTTCTTGTAAAAGTCTTCATTCATTGTATCCCATGTCATTGGCGCAAGTTCGAATGTTCAATTCATTATACGGTGGTACCCCATTGTCCCATCCTCTCATTATTGATGAAGCAACAACATCCAAACGAGAGAATTGCGTTGGACCGAAGAATCACGAAGATCTTCAAAAATGACTACTATGTTATCATCTCGTTCAGGTATCTCAAGGCTTGCCATTCTAATCTGTAGTTACAATACCTCTATTATATAACCACTGCAAGCCTGAACTAACCACGAATAATCTCATCCACACTGAGCGTTATTCCTTTACAGGATACCTGCGCATTCCACCAATTCTGGGAGAATCTTGACCAATGCAGGATCTCCACCAACTTCCGTCCGGAATTCACATTTATTTTCCTCGTTTTCTCAGAAGCACTGCTGTGGCACAATTGAGTGAGGGAACCTGAAGGCGGCAGCTCCAAAATCATGCGAGATTCCTGGTGGACCATGTGTTTAAGCATGTGTTTGGTGTAGTTTGACAAACGAACGTCTTTAAAAGAAACACTGAGTTTAAGGTATTATAACATAGTTGATTAACCTAACAGCCCTCTCCGAAGTCATATGCAATAATCTTCTGCATAGATGCAATCACCAAATGACGTGCTGCCTGGAAGATTTGTTGGTCTGTCCAGTCAGGATGTTCTCGATGGATTTGATTTGCATTGCCAACGGAAGTGGAGCAGACCAAAAGAAGACCTGGATTCTCATTCACACGCGAGTCTCCCAACACTTCAAGTTTTAAATATTTATACTTTTATAAAACTCTGAACTCACTAAATAATCTATCTGGACTCATCAATCGATGTACTGGTGGCGGAGCGGGGTTATTCAATTGGAATATGTGGGTTGTTAAGTGGTGGATTATCCAGGTACACCTTCAGCCACCGCCCTTGTTTGAAGGATCTTAATGAGGACACCCATGGCTGGGTGGTACCATAGATGAATGATCCATCAATCCATGAAGTCCGTTCATCGATTTGTTCTCGAGGTGAGTTGAGTAATCCCATTTCCAGTTGCTTTATCGTATTTGGCACGTGTGAATGGGATTTCTGTCTATCCCTCACATTCTTTATCAAATGCATTATCACATAGGGGTACTTGTCTGAATTTTAACTGTCTCTAGTGGACAGGATACTCCATTTGATTGCATTATTTCATAAGCAACTACTTAGGACCTATAATTCTTATTACTAATTTTTAGAGGGCGATAAAAACCAACTGAAAAATGCCAAAGATATCGTGCATCCTCTTGTATTAGGTCTACCGGACTAACTCCTTTGAATAGTATATCGGAGAGTTCACGGGCGGACGCAAGTGAGTAATTCACTGAATATACACCGTCTGAGTAGTAGGAACGTGCATCTCTATGCAGCCGACTTCCTGAAGGAGTAGGGTAACGTCATACGTCTTCTCTTCCGAAAAAACCTACCAGCAGACCCCCATTCAATCCTCGCCAGATTGTTGTTCCATCAGTCGTATCTTTGAATTTCCTGATTTTGTTGGATTCCTGAAAAGATAAACGAGTTTTTTATTTCCAGGCCACCAAAATCTATATGACGGCCTTTTAGTTCCTTATTGAAATCTCTAGATCGCACAGTCACACATGCTCCCTTCACTACATTTTCACGATTCGTGCATTTTCTCACTGATCGCGCAAATTTCCGGTCAGTAGCGGAGCAGAGCAAACATTTGCCTAGCCCCTCCACCAGAAACAATTATTTTCGTATCAATTTCGCACCTTTATTCCGTTTGTTTGCCTCTTTTTTGTACATTTTATCCTTTTTCTAGCGACAATTGACGGCAAGGTCAGTACAACAGGAAATTGTTCCTGTCGTGAATTTCAGGAATTTTTCCAAAATTGGTTGGGAAACTACCACTGTGTTGAAAATTCGAAAGATACACATTTTGTTATTTAGGTGTAAACATGAACACTAGGTAATCTATGTGTTATGAAAAAGATAGAACACAGACACCGGGTGGCATACAGAGCTTATCAGTAAACAACTATCAGTGCTTTTGAAATTTTGGAGGGGCAGAAATAAATGTTGCGGACAAATTTTGTTTGGGATTTGAAGTTATGAGAAATACGCAATTTGAATTTTTGAACATTTTTTTGTAATTTTTATCCCATTCACGCTTTGTAATCTAACATTTTGAGAATCTAACCGGCAGAGAAAATAGTACAGACACGTTCAATTTCTTCCAAAAATTATCAATATAGGCCACTTGGTGTCCATCTTCCTTAACTGTTTGCTATAATTCCTACCTCTCTTTAAAAGAAATCAGCTACAATTTGAACAGATCTTGGTCAATACATTTTCAAAGATCGGCTCGATCCCTCTTAAACATTTAAGCTAGCAGGTCCGCTCTGTTGACAAATTTTCCACCCGGTCCTCCGAAAGGAATTTTGTTGGTCAGCCAACAACCTAGACCATGAACCGATCGTGCAATTTGCCTGCTTATAAAAAACGATATCTAGGCCACCCATTTTTAAATACTTTTTTGCCTAGTCTTAGGTATGTGGAATAAATTCTAGGTCAGGAGGTTGTCTAGGCCACGTTTCCACTCACCTTTCCGGCTGCAAAAATTGAACTGAACAGTATAGCTCTGTACAGCACATTTGAGCGCATTGCTCGTGCGCCTTAGAGTTTTAGTTGACCTGAAAATATTTGACTATTTAGAAATTGAAATTTTGAAAAGCAATGATTAAAGGTCAAAAAAGATGTTATTTATACACATGCAACATTTCAAAATTCTGATAACAAATATTTATAGGAACACTTTTTCCAACAATACGGTGACTAAGGGGGTTTACTGATAGTAACAAATTGGAGCGGTACAGGAGGAAAATTTAAACCGGCTCTACCCATTTTAGTGCTACCAGCCGACAACTCGCAAAAAAATCAATCAGCCGCACACCCTGCTTCGCCTGGATCGTCAATCACAGCGTTTTGGAATTTTCCTAATTTCTAAAATTTAATTTTCTAAAAACTGGGGATTTTTTCTGTAATTTTTTTTTTACTTTTAAATTATTTTTTAGGATCACGCCTTTTTGAAAATAACTTTCGAAAAATTGTTCGCTAAAAGAGTATAAATAAGATCAGGCTTCGAAAATGTTTCAAAAAATATTTTTTCACGATTCTGCAACAACAAAAAACAAAGACTGAAAAAAAGTAAGAAATTTATTTTGAACTTTTCAAATCTACATTTACAACAAAAACAGTTCTTTATAGACAATATTATTAAAATCCAAATAGATTCCCAGTAGATTTTGTTTAAATATTCAGAAAAGGACCAAACTTTCAGTTTTTGTGTTCTTAAAAAAAAAAATTTTAAATTAAAATTGTGTGATTATCAGTCTCAAAAATTCCAAAAAAGAGGCTTTTAGTTCTGTAACTTTTGAAGATTCAAAAAAAAATTGGGGGAGCCAAAAACTCACGCTTTAAACCTGCCCGCGAGAACTGTCTGCAAATATTCAACTTTCTCATTTTTATTAATTTAATGAGAAAATTTAAAAAATAAAAAAAAATTTTAAGGCATGGATGCGAAAGGCACGCGGGTAATTTTAAGCCCAGGCTGGCGTTTTAACTTAGGCTTCCATAGACCAAATATTTTCATACTTGTTGAAACTTCTGTAAAGGTTTGAAAATTTTTGAACAATTTAGGCCCAAAACCTTTGTTCCTAAAAGCATTCAAAAATTCTTTGAACAAATTCCGGTTATACTATCATAATGGGAGGAGGAGAAAAATATAATATGATTCTTCGTCAGACAAAAATAAATTGGTGAAGAGAAAAAAATGAATTGAGAGAAAAAGAGAAAGAAAGACGCGTCTTCCGAAGAAGAAGGAAACCTCCTGCGCGGGATGCCGAAACAATAAGCAGCAGCCGGGAGTGAGGGAGTGCACTGCACTAAAAAATGCGAGAGATTCACAGAAAATCGGGAGAAACCCCCCGTATGTCGGTCGAGAAACACCTAAGACCTACTTCATATTTCGAACCGGTTCATTTTCATTGGCATTCGTATTATTTAAATTATTTTGACAAGGGCAGTCGTCGTAGATGCTAATGTTGCCAGTTTGACGGGATGGCCGTGTCACTTGGGAAAAGATTGGCGGCAAAAATCGGGGGGTTCCTAGCCACCCTTTATCTTCTATGGTCGGAGAGGCGTTTTCTACTTATTTTGGTAGATGTTAATTAAAAATTTCATCAATTTGGGAGTAATAATGTGGCTGCAAATCATATTGAAATTTTCTATACAGTCAGTGCGAGCCAGCCTTATAAATTTTCTAGTGCCGCCCAGAAAAAAAAAATATCCTAGGCCACCAATTTTTGATCATTAATTTTTTGGCTATCAAATTAAGTAGACCACTAAAGTGTTTCGTCATTAAAATTTTCTAGGCCACCAATTTGGCTTGACTACTAACCTTCTTGGCCATCACAATTTCTAGGCCACTAAGTTTTTTGTCTAGGCCACTAACTTTCTAGGCCACAAACTTTGATGTCAGGCCATAAAGTTTTTCCCAGTAGTATGTTTTGCTCTTCAAATTTTTCAGGCCACCCACCAAAATTCTATTCCAACATTTCTCCGTCCCATCAAAGTTTCTAAGGCCTTTTATAGACGACTTCTTAATTGTAAGTCAAAGTGTTTCAAGACCATTATTTTCAATACACTAAATATCAAAAAACCAAATATTTTCCTTCAAAAACTTTGCAAACTAAACTAAATGTTTCCAATACGTGCTTTATTTTTATATGTAGGCGTTTAGACACCCCAGTGGGGAGGAGTAAATGTTAATTCTTATGATTATTTCATTGGGAGTCACTTTTCTTGTTCAACGTCTTTAATATTTTTGAATAGGATTATCATTGGTATTGGCAAATAAATAAAATTGTGAGTGACGTGGTGATATTGGACATTATTTGATTTTAGTTTGCTTTTTGAAATTTCAATTTTCGGCACTTTAATAATTGTTCAAAATGGTCATTTGTCTAGCAAATTTGCATTTTATTAAAATTTTTTTCATTTATTACATTTTCAGTGAAAATTGCACAATCTTTCATTTAAAACTCACTTCTAAAATGACAGATGCGAAAAAATAATTAGGTTTCAATATTCAAATGAATAATTTTTTAAACGATTAAAACAAAATTATAGTTATTACAAATTATTTAAAAGATGTCTATACTTAATCAACACTACAATTTATGTTTTGTTTTCATTTACTCGAAAATCCAGAAATTTTAGGTTTTCGAGAAAACTTATTTGTTTTTAATAAGTGGTTTATATAAATGAATCCACTTGAAAGTGCGAAAATGTACTTAAAAGAGTCCAAAATAAGCAAATATCATCACGAAGCGCCGAACGTAAGTTTTTCGAAATGTTCAGTTATAGTTTTGGTGAAACTGCCAACTTTACGAGGTTAAAATTTCGGGTTTAATTTTCAAGTCTGTTTTTATACAAATATAAATCAGAGTTATAAAATTTGTAAAAAAAAATTTCTTGGTCGGTATTTAAAAATGTGGGTGATAGGGCCGTTTTTGACAGAAAAAAAGTTTTATAATTGTTTTACATTTTACCAACATAGGAGCTGCCTTAAAAAATAGCTAAAGGCTTGGGGTTTTGCCCTAATGAACAGTCCCAAACTACCAAATATAAATGTAAAATTATTCTAAAAATCTTCAAAATTTTTAACGATTAAAAAAATTTGCGAAACTTTAATAAAGCAATATGGCGAATAATTGTTTCATTCCCGCGATTTTTTGATAATAATTTTTTTGTATAATTCTTGCATTTAATGGCGTCATTGCTTGTTTACATGTCACCATGTGTTTTTCGGCAATAGTAATAGAGGTTTTCAGAAAGCGATTTTCTAGTTTTTGAAGCACATTTCGTTCCCGTAAAGAAAACTTGATAATTGGAAAGAAATGTGGCAAAACGGCGCAATTGACCAAATCGACCAAAAAAGTTAACAAACTGTATTTAAAAATAAATTAATAACCAAAGTAAAAAGAACACCCACATAAATGTCAAAAATCACTCACCCATTTTAGCTGAAATTCAAAAAAGAATTCGGTCCTTCCCTTTTTTTCTAAACAAATATCTCTTAAATCATACATAGTATAATTTTATATGACCTTTCTGACAGTTATATTTGGCATAGTGGGACCTTTATAAGGGAAGTCAAAAAACTGAACTCCGGACTTTGACATGCTATAGTTATTTTTCGAAAAAAGAGTGAAAATAATGATCCCTCCAAAAAATTTTGCTTCCGCGGACCAGGTTCAGCAAAGTTATGACGTTTGGAAAGTGCCGAAAAAAATTCCTTGACCGACCCAAGCAAAAAAAAAAGATTCTTCAAATTTTCAAAAAAAAAATTCTGAAAGTTGATAACAACTATTGTAACTTATTCAAAAATGTGAAAAACGTTTATCATGCACGTTTTTTCTCCCCACGGACAAAAAACCACATTGCTTGATCAAAATTTCGTGAGCAAAATTCTAAAAATTACTTTTTCTTGTAGAATTATTGGTTTTCTGTTATGAGCTATATGCATGGCATTTTTCACTCTTTTGGATAATTTACAAATATTTTTTCCTCTTTTCAGAATTTTTTTTGAAATTTTTGAAATTTTTTAAAAGGGTGTTCCAGCCACTTTCAACATAACTTTGCTGAAGCTGGCCCAGCTAATTTCTTTTGGAGAGATAGCGTTATTTTCACTCGTTTATTGAAAAATTACTATGACATGTAATCCGGAGTTCAGTCGACTTCCCTTGTTAGGGCAAAAAATACCCACAGACGGTACTCCGCCTAATATCAAAAAAGTTCCCACTCGAGATCACTTTTTTACCATCTCAAAATCGTTCGGTTTGTTGGTGGGGGGGGGGGGGGCTTAAAGAAAAACGAAAAAATGAGACACTTGTCAATTTGATGGTAGCAAGTGAAATGGAGAGATACCGGAAAGAGAGTGTAAATAGAAGAAGGGAACAAACACAAATTTCAAAGTTGTCGGAAGGAATTAGGGTATGGAGGATAAAATATTGGAAATTGGGTTTAATAGGATATGTATCTAATCCCGAAGAATATTATTAAAATAACCGGTTCAAAGATCGTACTGAAAAAATCGATAAATACGTTGTGATGGTCCTACTTCCGTCCTCTTTACACAACCTCGTCTTCTTCTTCAGGGCGCATTCCTTGTAACAATGCCCCTTTTCTCTCTTGATGGAGTGCCACAAAACAGTTTGGCAGTTACACAATCGGAAGGCGAGGAAAGCAAAACGGGTATCAGATGATGATTAAGTGAAACCGGAACTGATAAGTGAGAATGGATTGAAATACAGATAGCCGTAAACTTTTAATAACCTAGAATATTAGTTATTAAAGGTGTTATGTATGTTTCGAGAACAAGATTCTGCTTTCTCAATTTTTGAATGAATTATGTTTGAAGTAATTTAAAATTGCCGAATGACGGGTTTGAATATTTGTTTTTTTAAAAAGATTTTTCGTCCGGCCGATTAGTATTTCGCGAAATGTTTTTTAAAATCTTTGGGTTTATGTTCTTCTCTTTTTTCATAAGTCTAAGCTTAGGTTTAGGCTTACTAATTCTAATCCGAAGCATAAGCTTAATCCTAAGCCTAAAGCTCTCTCAGCCTACTCTTTTAAGCTTAATGAATGCCCTAGCTTCATTTTTTTTCGCAGGTTTTTTTCTCTAAATCTCAAAAGCGATGCTACGGACCAAAAATTGGTGGTTCAAAATGTGTGTTTCTATTTTTTCATCAAAAGTTATTTTATGTGACTATACAAACGAGCTGACAATCTTTCTTCAAAATTCCGTTTTTCTTACCAAAAATAGTCAATTTTTCGAAATCTTGCAAAAAACCGTTACCGTTTCCCTAAGTTTTGCTTTCCGTAAATCCTTGTACCTTATGTCGTATCACATGGCATTAGAAATATTTCACTTGAACCAATCTTGTGCGCGTGGAGTACAAGTTAAACATCATATGTGGTGGGTGCAATTGCGCTCTATTGAACAAACTATGTATCAACAGAACGCGTTAACATTATAGCGGTTGTGCAGGTGGGGAAAACAGGAAAAACGATTAGGCAAAACAAAAAGTCTATTATATAAGTTTTCTTCTACACATCTCATAAAGGAAATTCTAATTTTTTACAAAAAGAGCGGGGGGCGCGATTGTAAAGGTTTAGACGGAGCGTTAAGATCTTTGTCGACAAGTGGTTCAGCCGACACCCTGTGAATGTGATTGCCGATATTGTCCTTCTCGTTGATTGAGTCTTTCGAGAAGAGCGCCAGAATGACGTGCAGAATGAAGAGACCGGTGGAGAGACCTGGGAGAGTTTTAAAATTTTTGAGTTTCTAGGCCACGAGTGTCGTCCACTATTATGTCCAAGAAGCTAAGGACAAAATGATTGTTCACTACTGTTTCAAAATCAGCTTGAATCTCAGTAGAAAACAAATTTCACTGGAATATTTCAGCGCTCACCAATAGCAACGACCAGAAAAACAGTCTTAGCAAAGCACACGATTGCATAAGTTGGCACAAAAATCAACGGAAGCATGCATAGGCATGTCGACAGTCCGGGCTTCACACATTGGCATTGCCATTCCTGCCAGAGTACTGTAGACACGTTCTTGTGGAGTGAAACCCACGTACACGAAGTTGTAGGCCACGTGAGCGGTGTAGTCGACCGAGAATACCGTGGCGAGAAGGACGTCCACTTGGATTACCGGGTCCAGGTCGGCACTCCAAAGGGAGAGAGACGAGAACTGTAAAAACTTAAAAAAAAGTAACTTTTTCAGATTAAATCCGAAGAAAATAACATAATTAATAAGGATTTTGTTTCAATGGTTTTTTAAAGTGACAACTACTCATTTTCAGGTTTTAAAAACTTTGACTTGATAAAAAAAAACATTTTGAGCTACTTAAAAAGGTTTTGAATTCCCATCCAAAATCTTTGAAGAAATACAAATGATAAAAATTCTTAAAAAAAAATTGTTAGCAACCCAAGCGTTCGCTAAAGATCGTTGTCGTTTTTTCTCAGACAATTTAAAACATATCCCGCCATGATATATATTTTCGGAGAATATCATTTCTCGTAAAATTGTTTTCTCTGCAAATTTGAATTCTCCGCCAATCATTTTTCTCAGAAAATTTGACAAAAAGGATCAAAAACATGAAATTTCCGTATGGCAAAAAATGTTTTCTCAGAGAATATGAATGTCCGCCAAATATATCAGATACTTTTAAAGTCTCGTCAAAACGTTTTCTTCGAACATCTTAGGATTATTTGGATTTGTAGAATTTTGATCTTGATTTAAATTTTTTAAGTTTTCTGAAAAAAAACAACCATAACAGATACTTGCAATAACAGATGTAATCACGCGAGCAACTGCATTAAAATTTGAAATACAAAACAAACGATTGCCATAACACAGCTAGTAACCGCAATCGATCCAAGTAAGTCAGTGGCCAACATCAAGATGATACTGAGAATTGCAGAGTCACAGTCCAAGAGTGTAGTGAATTGACTCATGAAGAAGTTCGGATATGTTGCATTGCACGTGCTCTTTCTGCCCATTCAGACATACGTTTACCGAGCCCTGAAGTGTCAGAACCCTGTGTTGGTCTGAAAATTTGGAAATTATTCGGATTGAAATTGAAAAGTGTCTAGGAATTAAGTTTGAACTATTTGAGAAGTTTGTATTTTAAATTTTGCGCTAAGTTGCCTGAAGAAAAACTAATTTCGAAGTACCTATATACCTACAATATTTTTCAAACTCAATCTTTAAATTTCGCGCCTAAAATATTTCGAACTTAAAATTTGCGACAAAACAATTTAAACTATTTGAGAAGTTTGAACTTTTAATTAACATTTGAACTCTTTGCGCCAATTTTTTTGCTTGGAAAATAACTTTTGAAATTCTAGTTGCAAGGAAATTCAGAAAAATTAAGGATGTAATTTTTTTATATGAAAAACTCTTAGAATCGATTTCGCGAAAATTTTTTACTCCTCGTGAATTGTCAAAATTTAAATTGAGTTTTACAAAAAAAATTGGCGGGAACGTGAAGTTTCATTAGGAAATTCAAATTTGATAGGCGTTTGACTAACTTATTATCATCTCCTGATATTTTACAAGGGTTCCGGGCGATCGCATCTCATCCATGTAGCGTCGGAAGATTATCATAAGATGGGTGGTAATTTTCTCCAACCAGAGTGGATAAAGTATTCATGGTCTTATCAAAATGCACATACTGCCGGAAGAAAAATCAGACTTCGATTGTCTCCACGAATACCTGGCACGTGTTCGAGCCGATCCATCAAATTGTTGAAAGAGGCGTACTGAAAATTGAATGGCCTAGTAAGTAAAAATTAGATCATGAGCTTACCTCTGCTTTGATCTCGATATTTGGAGGTTTGTTCACTATTACTGTAATGGGAACGTAACGGGATAGCAAGACTGGCCTGCAAAAATGATAAATGCTTAAAAAATACAACTTTTTTCTTTTAATAACGTAAAGAGCTTTTTAAATCGATAAAATCAGTAAATCGGCATTGCAACTGTAGACCAAAGATAACAATTATTGATTTTTCTTACAAAGACATTAAAAATAAAAAAAACTCAATAAAATTAGCGATTATCTTTCCAAAAATCTGAAAATCAAGTCAAATAATTTTCTTGTCGGTATCTTTTATGTTAACCTATAAATACCAATTATTGATTGTCTGGAAAATCAGTAAAGATTCAAATAGATTTTTTTGAGAACCTAAAAATCAGTAAAAAATAAAAAAGTTTTTTCAAACGCTTACGTTTCAAACAAATTCTTGATTTTACTTTCAAACCAAATTCATATTCGACAACGAATCCGCTTCGTTATGGGTCAGAAATGCCTTAGCTGGTTCAAAGGTCGTTTTCGTGGTCACATACTCCATCATTGAAGTTGTCAACGCATACATCCCAAGGCGCACCATACTGCACGCTACACGCCCCTTCAGGGAGCACACGAAGCTCGAGGACTTGGAGAGCCACGTGTCGGCTCCCGGGAAATTTTTGGCTCCGTATCATTGGCGATGGATTGGTAATCTGGGTCGTTGCAGAGGAATTCAATTGGAGCTAGGATCGTATGGGTGAAGATGTAGTCGAAGAGGCAAGGCGAGCGAGGCAGTTAGGCAGAACAAGAACATCTGGAAGATGAGTTTTATTCAAGCTAGCCCACGTTCTCACAAACTTGGCTGCGTGCCAAAGAAGGTTACCTGAGGCGTTGGCTTAGAATCCATTCCAAAAGCAATAATATTGGTGAGTGAGGTGATTTTACGATGGTCCAACATCGTGACAATCACTTGTTCCAAACGGCGAGGTCTCAAAATTTCATTTTACGATGCTATTCCAATACCCCTACAGTACTTTTGCAGTTTCTCTACAGCACCCCTATACAACTACGGTACATTTATTTATTTGTATATTTGTTCATCAGGGAACGATCCTAAAGATACAATTACAACAAGGCAGAATCTTTTACAATACAATGCCCCACCCTCTTTTTCCGTGAAAGGAAACTTACGTGTCAGTAATTGCAATATGATGTTTCCATCTGAGAAGTAGAATAAAAGCATCATCAACTTTTTCCAATTCCAAGTACCAAAAACTGGCGTAACACATGTAAATAGAGAACGACGGGAAGCCCATCCAACAAATTGCTCCAAACGAGGCGGCAGGCCATCGGAGTGAGCAATGATGTAACCAGATAGAATGCCATTTTGACAGATGACAGGCGGACAATGACAATGATGACCTGCGTCAGGTGGGAAGAATCCGATTGTCATTTCGTAGCTTCAATGGTTCCTCGAATCTCACGATTTGCTACTTGGTCACTGACAGTAGATGGTGAACTGAACGTGCTCGAAGGCAGAGGAGTTTGTTTTTTGGAAAGTTGGAAGAGCTCGTCGATTGCGCCCTGGGAAGTATAATTACGAAATGCCGAGTGCTTGCCAGTTTTTTTGATTATGTAAATTTGCTTCCCAGAATCCGAAAATTTGGTTTCCCGCAGAAAAGACTGAAATTTAAATTTCTAAAGATTGTTCAGATGTTTGTTTAAGTTTTCTTTAAAGACAAAGATTTGATTTTCCTATTGAAAATACATGGTGAAAATTCAAATTTACAAAAATTGAGTTTTGTTATAAAAACAGACTGAAAAATTGAACTTCCTGATTAAAATTGATTGAAATATAAGAGGCTCCTAAAAATCTTGAAAACTCGAAATGTAAATTCAAATTTCCCGTCCAAAAATTGACAAAAAAATTTGATTCTACTTTCCTGAAACAAGTTAAAAAATCAAAGGTCCCTCAAATAGTAAAACTGACTCAAAATTAATTGAAAATTGAAAGCCGTATGAGTCTTCTAGGCTATTCTCACCAAAGCTTAAACGCGAATTTTCCTTCTGGACATGTACCAGACCTCGAAAAATACCACAGCACCAAGAATTTGGGGCTGAGCCTCTTGGTCGGTGGTTCTGAAAGTGTCAATGTTTTTTCACATTTTTCCGGAACTTTTTATAGTTAAAAAAATGAAGTAGCTGGAAAGTGGCTAAATCATAAAAACCTTACTATTTTTCCATCAACTTTTCATTTAACATTTCAAAAAAAATCTAAAATCCGCATTACTCAAGTGAAGTCCCAGGAAAATATACGTGCCAGTCCGCTACATATCCGGATAGGTGAGAATACACTTGCGTGGCACCATGTATGTTTCTCCGCGTCAAATTCTGAAAATTGCCATCTGGTCGTTGAAGAGTTTTCTAGTCCACGACCACCACCAACAGTTTCGGTTTCGTTCGACTTTTTAGAATATCGAAACTGAAAATCCAACAACTTTTTGAGAAAAACTTACAAAGCTGATAATGTTTTTATTTTAACTTTTTTCACCATCATTCATTGACATTTAAGAATATAGATAAATGGGATAAGACCGTCCAGGTTTCTGTTCAGTTCTCCCTGTTGTTAAATTCATTAAGATTGTGGTCCCCAAAAAACAATGTTTCTTTCTTTTTTCGATTTTCAATTTTTAGATTTTTCAATCTTCACTAAAAACATCAATAATTGAAAAAATCGAAAAATGACACCCTAGACCACCACCTACCTCTAACAAGTGAAAGGGGCTGGAGAGTGGATCGGTAGCAATTTTTTCTTCCTTCCCATCATCGTGGTAGCCGAATGCCGCCGATAGTCGATTGTCCACAGTATAAATCTAAATTTTTTAAATTCCCGCCAGAAAAGTGGGCTTGACGGAGAATCAACTTACGTCTGCCAGTCCTACGCGCCTTCCTGGAGAATACTAATTTTCGCGCTGGGCGGTAAAAATACAGAATGCTCGTGCCGGATAGATGTCGAGTCCGTAGTATTCCATAGCCAGATACGGTTGAGTATTCACTGAAAAATGTAAAAAAAGTTTTATAGACATTTCCGCCAAAAGATTTAAAATAGGAGTTTTAAAAAAATTAACAAAATAGTTACGAACGAAGTTTTCATTTGCTTTAAAGTTTCTTTTTTTTCTTATTTATTTTTGATCAACTATTTATATTGGGTACTTTTTTAACTTCAAGTGGAATCCAAATTTTCTTCCCAGTCAACCAAACATTGACCATATCACAATAAGGGAAAAGGGAGAAAGGGAAATAGTTAGAAAAAGAAAAACATTGCGAAAAAACGTGTTATTTTTGACTGGTGGTGGAAGTAGGCTTCAAGGTCAGTAGTCACTTACTATCCAGCATCTGAATCATGATAAAAGGCTTTGCGAATATCTGGCTCTAAACGTATGTGCTACAAGTCCTGAACTGAGAACTCATAGGATGTATAAGAGCTCACTGAAAATTGTCCAACTTGAAAAATTTCGATTTTTTATGTTTATTAAATTTTTTCTGGTGTAAAATAGCAGAAAATGCCAAAAAAAAATGTATCAGACACAACTTCAATTTTTCAAACTTTTCGTTGTAAGACCATACAAGATACAATAAATTGTCGTTCGAGAGCGCTTTGCCCATGAACCCGTAACGGAGATTTTCATTCGACTACTCTATAGACCGCGTTGGTGATTCTGAAAATGACTTTTTCTTGGAAATTTAAAACTTTTAATCTGGGATTTTTCTGTTTTTTCCAAAAAATTATATTGAAAAATCAATTAATTAAATTTTTTCAAACCTATGGTGATTCATGATTTGATAACAAGAACATAGCTTCCTAGTTATAATTATCCTCAGTTTTCACGAGAGTAAAAAAAAACGGTAATAAAAACATTCTTTTTTCTATTTTTCTCAATTTTTCGATGTATTTACCAAGAAAATCGATTAATTTATCGATTTTTTTTTCAGAATATCTGACCGTTTTTGTTATTCATCGGAAAAGTTCAATATTTTATTTTTAGGAATTTGATTTCCAAACGTATATTGGTGGCCAAGTTTTCCCATTACTGATCGACGCATAAAAGTTAAAACCTCACAAAGTATCGAATAAACCGGATAGGCGGCTAACAGCCGGCACTGGCACGACGGCACTAATCACATCCCATCCCATTGAAACTTCGAAATTTTTTTGGATAATATTTTAACAGAATTTAAAGCAGCATGCAAACTCTCTCCAACAAAGAAAAATGTTTTTAAAAAATTGAAATTCGAAACACAAGCACGTGAAGCAGAGAATGCAGAAAACAATACCACTGTCCCAAAGTAGAAGTGAGGGAGGGAGGGCAATTATTTGCAGAGGTGACCAACGGGTTCGTCGGGTTCCAATTTTTCGGACACGGCGCAGAGGATTTGAGTCATTATTATTGTGTATAGAGAGTGTAAGAGAATTAGAGAATTTAGATGGGAAACTGTACGTACTTCTGCGAAATGGTGCACTTTTAGGATCGGCGGCCTAGAAATTTACATGGTGCTCTAGATGTCTAATAGATAGCCTAGATCTTTATAACTCCAGACAATTACTTGGTGGTCTAGAAGTTTTTTTTGTGACCTAGAAATGCAGATTGTGGACTATAAATTCACTTGGTGGCCTAGAAAATCATTTGGTAGAAATGTACTGGCCTGGAAATTAACCTTGAAGCTTATGCTAGAAGCTTTGTTAAGTGAGCAGACAGCCCAGCCAAATTCACTTGATTGCCTATCAATTCACTTGGTGGTCGAGAAATGTACGTGAAAGCCCAGCAATATTTACTTGGTCTAAAACATTTTTCAGTTAGAAATACATTGGAAAAAATTTCGATTAAGATTTATATTCTGGCGTTGGATGTGGTGACCTAGATATTTGTCAAGGGACTGATGAATTCATTTGGCGTCTAATTTTTTTGGTGACCTAGAAATTGATTTGGTGATCTGAAAATTCATTTTAACATGACCTGGGAATTTACTTGGTGGTCTAAAAAGTCTCATGGTGCCGGTCTTAAAGTGTGTTGCAAAAATTATACTACAATATTTAACTTTGAAATAAAAATTCAGCTCTAGATCTGCAAGAAAAATCTGTATTTTCTCAATTCAGGATTTTGATTAGTTAAAAAAAATCGAAATGATTGTTTAAAACGCGTTGCAAAAAACAATTTTGTAGCTCAGGAATGCGCTATTCTGGGGAGTCAGATTTACTGGATTTTACTTTTTTTCCTGCAATTCCAATGCAAAATAAGGTAAATGAGAAAACTAACACGGCGGTACATACAGGGGCATCTTGAATGTAAGGCAGTGTTTAGTAAGTGGACCGAGTGGACGGCAAACGCTTGTATTTTTCCTGTGTCGATGGGGGATATCTGTACCGCGGTTGCACACAAGAAACAAGTATTTTGATGATGATACGAATAAGAAAAAGAAAAAGGCAGCAAAAAAGTGTGTGGCAGACGACCACCGTCCATCGGATTAGGCTGAGCCGGCTAAGGCAAACTCGTTCTACCGAACAGAGGGCCGTTTGCAACCCCCAAAATCCTCTGAATGTGACGTCATTGTTGGGGCGGCGGGGTGGCGTCCAATAATTAGTGATTTTTTTTTTTGTATTCTGGAAAAAAAGGAAAAAATCGAGAAACATTCTTTTGTGTTTTTGGGGAGTCTGTCATGTGAAATTTAAAAATGTTGGGTACAATCAAAAAATCGTTTTGGTTTTTATATCTTATTTCAGGAATGTTTAAAAATCTCAATCGTTTTTCTTTGAAAAAACAAAAAACAACAAACATCAGCATCATTTTCGATTTAATTGTTTGTTAAAAAAATAGAAAGCGGAAAACACAAAATTTTCCGATCTTCTCGAAATTCACAAACTCATAAAAAAATCGAACTCCCCTTGTACCCCAGCACCCTAGCTGAGTCTTGCTTCCTGGCCAAAGGCATGGAGGGAGGCGGGCACCTCTTTTGCTTGACCTAAATAAAGGTGATATCCCAGTGATAAGGAAGGGTAATGATCCGGAAACCGCCTACCAAAGTGCATAGTTTCTGCGTTAAAAAAAGTGACAACTGACATCACACGGATGCTACAAATGGGGACTCACATGCCGGAGAGGGAAAATTGTAAATTTGTACGGGTAAGGGGATCAATGTTCAGTGGTGAGGTCGCGAGGACGGAGGGAAAAGGTGGAATTAGAATTGAATGGGAAATTGGTGGCAAAACGGTAAACAGTTCTTATTATCAAATGCATGAGGGATGGAGAAACCTAAGGAAACCCTTGCAGAATTTTGGAGGGGGTGATGAAAAGTATTGGCAACACCTTGGTGGACGAGAATTTTAAATTGATGATCCCATGGACTAAAAATTCAGATGATGGCCGAGTTTTTCATATTCGCACCGAAGAATACGGCAAAATGATGGCCTAGAAAGTTGTTGGAGCGACCTAATCTTTGTTCTTACAAATAGATCTCTAATGTTTCATCGAAGTCAAGGGATGTGAACTAGAAATATAAGATGGTGGCCTAGTCAACAATTATATTTATGGTTCGTCAAGAGGCCTAACTCTTCAATCACGAAATATTCTAGAGTTTAATCCTATAATTAGTATTGTGGACTAAAAGTCGAGATAATGACCGAACTTTAGCTCTCAACATCAATTTGGCCTTGAAATTCCGCCATGGCCGAATTTTCGTAAGTCGACCCCAGCGGTGGCTACGAGCCAAAAAACATAATTCCGCATTCATACATTTTAATATGAGGGAAGCCAGAAGTGCGAGCCTCATTATTTTGTGAGTACATTTTTGACTATCGTGCCAAAATTCCAAAATCCTCAAAAATTTGAAATTTTCGCGGCACAATTTCTGGTTTTAAATCTCTTTTTTTTAGTGTGATGTAGGGCTTTCCAATTTGCATAAAATAAAAAATCAACAAAAAGCCAAACATAATGTCAAATGGTCAGTTGCAATAAGAAAACAAACCTGCGTTTAGGATGGCCGAACCAGAAAAATAATTCAAGCTTTCGATTTCGCCCGAAAAAAATGAGGATCAGAATGAGAAGGTGTCGCCTATTAGAGATTGGAGGTTGTTGAGAAAAAGAGAATAGTGGAGCGGGGGGAAAATGATGAGGTAGAACGGAATCGAACATGCAAATAAAACGAATGTATTTGGTAGGAGAGGGAAGGTTACACTGTGTGTTCTGTGTTTGGAAAAGGATTGAAGTGGTGGAGGACTCTGGATTTAATACTACTTACCTGTTCTGATCAGGTTCAGAGGTATTTCAGCAGTCGCTCTTGTATATTTTGTCTTTTTAAGTTTATTTATCAAATCTTTTTTTGTAACTTTGAATCTGATGTCAAACTTTGGGAACTTTGAACTCGATGAAATTGCTCAAAAAGTAAAAGAGAATTTGCGCCCAACTCCTTTTTCGAATTTTTTTCGAGATACTTTGATTCTTCTTAATTTCAACACACAAAACTTCGCCAAAATATTGTTACAAAATTAACATTTTTATTTGTAAACAGCTGCTAAAGCACCACAAATGTGAAATTGATGCCTAAAATTAAAATGGAGTTTTTCAAAAAAAGCTGATTGAAATAAGAAAGTAAGCTAAATGTATATATATGGGGAAGATGCTATTTCGAATCTCGCGTTTTTTTAGTTGGGCATCTCCAAAATATGAAAAAAATACAATAAAAAGCTCCAAAAGATATCCAGGAATTTTTTCAAACTCACCAAGAAGTATGTTTTGATAAACAAAAATTTGAATTTTTCGAATTTTTTTATTCGTATAATACCTGTCACACTTATTTTCAGCATAAGAGGAAAAAATAAATGTTGAACTTTATTTAATGATAAAAATAGTTTGTCGAAAAGTTTTCGTAAATTTAAAAATTTAAGTTCTACCAAAATAGTTTTTCACCTGGAACAAAAAACAAGAATTTTGTTTGAGCTTATATAACACTACAACCACATTTTTGAGAACATGTCTAGCCTCTGTCAAACAGTTTTCCGGTAGTGGGTGTGGTTGCTAGTGATCAATAGATCTTCGTAAAAAATCGAAATTTTCCGTTATAGCCTGCTTTATTTTATGTGTTTGATGCTATAAGCGTTTGGATTGTATCAGTCCATATGATTTGACATTATTCGCAATATTTTTTTAAATCCGAATGTTTTTCGAGTCTCTATTTTTTGTAATTTTCCAGACGGTTTAAGAGCTAAGTTGTAGCTATTCTTTCCTATCAAAAAATGCAGGAATAAATACTAACTCAATTTATGCAAGATAAAACATTTACAGTGGTTTTTTTGGTCGAAACTAAATTCCGCAGAATTTGAAAATTACTGAAAGGGTTTTTCCTTTTTTAATTTGTACTCCCTACAGTACCCGTTATTTTTGAATTACAATTGGATGTTCGTACCTAAAATTGACACTTTTTCTCTAGTATATTTCCGAATTCAAAATTATCAGTTGAAACTAGATCCCACCAAAATAACAAATTGATAAGAAAACGTAGAAAGGGGAACGTGTACCCTTACAATAATATTAACTGTTTTCCCTCCAATTTTTTTTATTTTTCAAGGGTTTTATTCTTAATTCTATTCACAATTTTTCAAAAAATATTCAGCAAAAAAGTAGGCGTGCTGACTATATTAACAGTATAAAGTGAGTCTTTTTTGTGAGCATTAAAAAAATCAATTTTTTGTCCTAGCTTTGCAATAGTGGCAGCTCAAAAATTAAATGCATTTGTTCCATTTTCCGTAAAAAAGACAGTGGAAGAGTTTTTATCCGTACTTGGGCAGGCTAATATTTTGTGGCCGGTACAAATTTTTCGCGTGGTGCCTAGAAACCTTTTTTACGTTTTTTCTCGGAAACTTATTTTTTTCTGGCCGTGAACGAGTTTTGTTTAAATTTCAGGTGCTTTGAATATTTTGATGACTAGTTTATATTTTCCTGCTTCTAGTAATGCTTGGCCAAACGTCTTCACGTGGTCGGGCTTTTCATCGGTTAGCTTGATGCCCTAGGAACGTTTTTAACCTGGCGTTCTCTAGACAATAACTACCGTGGACTCGAAAGTATTCTACGCCACGAAATATTTGTAGCCTAGAAATCAAAGTCACTACCCGTGTGGCCTACGTCTCCCTGAGCATAACGTAGTCCTCGAGAAGTCCAGTCGACGGATACTGTCTACAAGATTAACGGCATGATAATCCTCCTGGTTCGATTACGATGTCCACTCATTCACTAGTCGGCGTTGTTGCAACAATGTGGAAAACTTTTTGGCATTTTTAAAGATTTTTAAACACATTTTTTCTGTCGGAACTGAGAACCGGCTGTTTGTAGAGAAAAAAATTGCATTTACTTTCCTTGAAAAATCTGTTAGCGTTCTTCACTCGCTGATTTATGTACCGTTTAAGTTTCAGAGACAGCGTGGGATTGGGGGACTGGACGCAGACAGCGAGTGAGTTTGCGTCTCCCTCTCCCTCCCACTCTCTCATAAGTTTTGAGTGTTCATAACTCGGAGAGTGGAGCTATCGAAAAATTCAAAAAAAAAAAGCCTAACAAAAAATTAATATAAAAAAATTCTACAAATTTTTAGTTGCTAATTTTTTGATAGCGATGCTAGGTTTTTAGAAAGGATGACGTTTTTAACTTACCTCGACTCTTTTTGTGTTACCAAGTTAGTATTCCTCTAACAAACCGCAAGACCTCACCTCATTGTAGCCTATTGAAATCTGTAAACGCCCAACGCAGGTTGCCTAGATTTGATATCCGCCTCCATCTCAGCCGTTCTCTTTCCATATTCTCCTAACTGTTTGCGTCTATTTTAATAATGGGATTATTCGGATTTCCTATTTCCGCTCAAAAACCAATAAATTTATTTTGTAGAGCGAAAAATTCTACACATTTTTGGAGTCAGCAAGTTTTTCAATGCACCTCTCCTCGCTGAGTTTCGTTAAGATCTATGATAGTAAAAATATTTTTGGGGCTAGCTATTGTTTTAGGATAATCAGGATCGCACGGACTTAAGTCTAGCCTCATTCCGAAATTTGTGAACTCTGTAAGTTATGTTGACTAATAGTATCCCTCTCCAGCTGTTGTTAATCTCCTCCTTCACTCCAGTTGTGATCGTTTTCGCTCTTCTCTCGCTTTTGCGCCCTCTCTGTAGGGTCCAGAGAGTATCAGTTATCTCCAGGACGCCGTGTGACGTCATCGCTGACAAGCCGTAACCTAGATAAAGCGCCCGGCAGAAGACCTGTTTTACCCCGACATGCCATTCGTGATAAATTTAGATTAGTCCTCTCACACTCTACATCTCTCCATGTTTTTTCACACGAACTATTTGTGTTTTGAAGAAATATCTTTAAAACTTTGCTTTGACTAATTGATAGCATAAAATGTATTTTTTCCGTAGCTCAGCAAATGGCGTAACTAAATGGTGTGAAATGTTAGATAGGGGACCGGTTTTGGCGGAAATCTCAGAAGAAATGGAGCCCTGCCTGCATAGAGACCGCTTTCGACTGATGACATCACAGAGTAAGGTGTCACATCTAAACACCATTCTTATTCTCTTTTTGAGGTCCAATTAGACTAGGCGGTCAGCGTGCTCTCGATTGCCCTAGCCGATGACGTCACATATTTGCCATTCACAACTTTCTAAACTTCAAACATTTTTTAATGTTTTCCAAATTTCAGCCGATTCCTCCAATGGGAGGACTCCCCTCCAAACATCACCACCTAACTGCCGTCCACGGCCACTTGTGGCCCAATAAAGGGTAACGTCGGATATGAGCAAGTAGCTCATAAATTGAGCTCTCTAAAGTTAAGATGAAAAGAAAATTATTTAGGAAGACGCTTCAGTGGTGTAGGGGTTCCTTGGATTACCGTACGCCACCAATTGGAGCCTTGCGCTTTAATAAGCCCTCATCGGAAACGGAGCCGCTGTGGATTCTGTTAGCCGCTGTTCGGGCCATATTAGGAGTCCGCAAAATGATGAGCCACTAGGGCAGGTAGGCGCCTAAATCAGAGCAAAACGCTGTCATTTTTATAAGGCTGTTCAGTTTCTAAGGTGAACACAGTCGGGAAAAGGTGCACTGTTTCAGCCTGAAAGTATTCACTCCAAAGTGGGAGTCAAATGAATCCCGACGGCTTCCCAGTGATGGTCTTCATCCATGGCGGAGGCTTCGGTGTTCACTCATCCAGCAACTATGGCTGCGTTTCATCGCACGAAACCTGCACCAAGGACGTCGTCGTGACCACCTGTTTTACTAACGCGTATGCTCGGCGGGATTCTTCACCACCGGCGAAGTGTGCCTTGGAAACCTTGGACTTTGTCCGGATCAGACTTCCCTGCCGCAGTCGAGTGGGTTCAGGAGATTCATCCGAGGAGACCCTGAATGTTACAATCTTTTTATGGCCAAAGTGCAGGTGGAGCATCTGTGGATCCCTTGCTTTGCCTATCGCCGCACTCGAGGGGATTGTTCAATCGGGCGATTCCGATGGAATGGAGAATGTGATGTTGCGAGGCGGACTAGTGAGTAGCAGGCTCAGTTGTCGAGGGAGTTTGCGAGATACCTTGGATGGGAAGTGGTAAGTGATTAACGCTTAGTCTTCAGATGTTAGAAAGTGCGTTGTCATCAGAGTTGGATTGAGTTTTTTTAAGCGTAATTTATACTAAAGCCCTATCGAAGCAGTTTCCTTGGCTACTTGGCCTACCACACTCAGCCGACGCCCGTCATAGCAACCACCTGGAGGCTCAAGACATTTCCTATAGTTATGTTCTATTGCAAATTTAATACGGTGATTATTCCAAAAATCTCATGACGTATTTTACCGAACGAGAAACCAGTGCAAACTTGTTGAGTACCTAATTACTTCACAGACAACGACAGTGAAGACCTTGTCCAATGGATCATCGACCAGAAACCCATAAGATCGAGATGGGCATAAACCCGAAAAGAGGATTCAAGCATTCTCAGGCTGGAAGCTTGTATTTGGTGCCAAACTTTTACGCACAGGCGACTTCTTCCCGAAACCCCCAGCATTAGAAAAGACGAAGCCCAAAGATTCGAATAATGACTCGGCAGGAACCACCAAGAACGGGGGTCTATTTTTCAGTGAATCTTCTGAAAATTTTCTGAAAATTTTCTATTATAGTCGCCCTCGGTGCCTTATCGAAAAATCCGGAAGGAATTAGTTCATGGGAAGAATCTTTAAAGAATGCGACTATGGCGAGCGTGCTGACGCGATGTGCTGCAGATGGTCTACGACTTTTATGTCAAGGAGGTACATCCGATCATGAGAAGAATATGCATTGTGAAGATAGGTCAGGCATAGAGCCTACAGGGCTATCGAGCCAGTGATTGAGTCCATTGGAGACTATTCTATCAACTATGGTACATACCGTCTGGCTAACATTATGACGGATCTTCAACACGATGTATACCTTACTTCTATCAGTTGGACTATCATACTCTGCAGGATTCGGTGTTCCGGTGGCTTCGGAGCTTCCGTGTTTGGGTGAGTTTAGGATGGGTCAGATTTTTCCTAAGCCCGGGGCCACATGCTCTTTGTAGATCAGCAGTTTTAGAAGTTCGAAGCGAGAAATGTATGAGTATGGGTAAAACTTTTAAAGATTGAAAAGAAATTATCCAAATAATAGGACTTGGTAAAAATCCCTTAGGCTACTTGTACGGCCGTAACCTGTCACTAACGATTCTAATAGTGTACCTTATCTGAACAGTATTGCCAACTAATTGAAATTAATTCTGAGACTCCGAGATTAGCTAGCGGTCCTTTTCGCTGTGGCCCAGTGCCCATTTCCTATGGCTCAATATCCTTTTCAGGCTCCACACATTTCACGGAAATCAGATATGTGCTCGGGAATAATCTCGAAATTATCCGACCAAATGATAATGATAAGAAGATGCTTCACGTTATGACAACTTATTTTACAAATTTTGCAAAATATGTTCGAGGTCCACACTTTTGTGTACTCGAAATTAAGCTGCTTTCAGAAACCTCACTAATGGAGAAAGGAGACTAGAATGGCAAAAGAACAACTCGGCACACCTTGGCGTTCGCCATTTCAAGATTGATCTGGACGATTCTGAAATGGTTGAGGACTCTCAGCAACGGAGAGCCGAGCTATGGGATAAACTGAGAGCATTTAATGTTAGCAGGGCTCACATGTTAAATTGCTGTTATTTTTACTTGATTGATTTTACGGTTTTATAAATAGTTTAGATTTGTTATATATTTATTTTTTCTGAGTTACATACATACATCAAGAAACATTTCTCTTGCAATCTAACTGAATTTTATTTTATAATCAGTTGTTTTTATTAATCCTGTACTATGCGGACAAGCGTAAAAATCTGTTTTAATCAAGAACTCACCTACCAATCGTTAACACCAAAAACCAACACGGTTCTGAAACAAACGATGCATAAGCTGGCACCATTATTAATTATCCGCATACAAGGTTTATCAAATAAAGGAAAAAGTCGGAAGCTTCCAACATTCAATATCTCTATTATACTTTCCCCTTTCCATGTATGTGCTTTTTGTGTGAAACCAACTTAACCGCCAGAAAGCACATAATCTATAACAGAGGTGGGCGGCAATTGCCGCTCGGCGAACATTCTGATTTTTTGGAAATTTTCATTTTTGGCTAGAAATTGCCGCTCTGGCGTTCGCCGGATATATTTGCCGAGGCGCAGTGTTTAGAGGATCCTCGTTTTACCGGAAACACTTAAAACTGTGCCTTTTTGAAAATATTTTATTTTTATTCTTTTTTTCGGCAAAGTTGCCGGTTTGCCCAATTTGGCAATACGCCGGAAATTTCAATTTCGGCAGTCGGTGCAAGTCAATTTGCCAATTTTCAGAAAAAAAATTTCGACGCCCATCCCTCATGCATACCGTTTTTGACTCAATTTAAATAGTAACCTTCCACATTAATGTAGTAACGGTAAGTTTGCATAATTTGTTTGAACTTTGAAAGCCGCTGGGCATCCAGCACCTGCGGTAATCGATCTCCTTAAAGGGTGTTTTCGCAAATCTACCAACATAACAGGAGTTTGTAGAAACATGAAACCGAAGGACAACACATTTTGAAAGTCACATTTATGTATCTGCACTTGCTAGCTATGGAGTCAATGAAGCATTACGAGAGACATGTGTTCATTCCCGAATGGAGTATGAGTAATAAGGTTCTTCGTTCACATTTTATTATTACAGGCTTGGGTCCCATATTGATTCATATTTTACTTACTTTTCAATTCATGTGTTTGTAATTTTTTTTCAATTAGAATACTATTATAATAAAATTTCTAATAATGGACAATCGAAATAGTTGCAAGTAGAATAACTATTTGTACAGTGATGCCTATAATTGTGGATGTTTATAATGTGTCTAATATTTCAACGCAATCGTGACACAAGCTCTATAGTATCTCGTGAGTGCATTTTCGGTGAGGTTTCAAAAAAATACTCCCTTGCTCGCCATACGTTTTCAGTTAAAAATTTCTTTAATAAAAAATTATACTGCTTATTTCTCGAACGATACCTTTAATGTTAACTGCGCCTACCATGTCCTTCAATCCCACTAGTCAGTTATTCTTTGCAATTAAATGTCATGGAAACGCTTCTTTAATGTCTAAATCATGGATATCTCCATCTCAACCATCCATCGTTTTTTATCATCATCATTCTCGTGTTCTCGTTCTCCGGGTCGCCTCCGCTTCTTCATCATCATCACCACGACAAAACGTTCTTCCTAATCGACATAATCCCGCATTTAATTTCTCGAATTGTTAGGTATGAATGACACCCAAAAACGGTCTCATATTCGGAAAAAATGGGAAGATTGATTCCTAATTTATTGGTTTTGACCGGTTAACCCCCACACATGTTTTTTGTACCTGCGTCTATTTTCGTCTAATTTTAAGAAGTCAATGCCTAATTGTCTTTTTTATTTTCTGTGAAGTGAAGTATCAAGATAAAATCAGTTTGGCGGTCGTCTCGCTTCTTTCTCATTTTTCGAAATACCCGTCGCAATATGGTTTTTTTATTACACATTTGTGCGCACTTTTTTGCTACCCTACCCCCCCAATTCTGACTCACGCTTGCATTCCGGAGACTGCTCTGAGAGTTATAACAAAACATAATTGTTATATAAATGTCAAAGTTTTTCGCAAGCTGAAAATTTTTGCCAGCTGAATTATTCCTTGCCCCTTCAAAGTAGCATAAGTCTAAAAATGCTCGAGTTATTGGAAAGTTGCTAATTACAAGTTAAAGAGTTTAATTGACTAGTTTCTCGATTTACAATTTTTGAACTTTATTCCTTGAAACTCTAGCAATGAGGGGCAGTAAGTGGGGACTCCCCCACTGGGGAGGGGAGAACCTTGTCAACCCACTAGGGAGGGGAGAACTTTGTCAACTTTAAAGCCACGTCCTTCTGCAGGGAAAAGACTCGCGCTATCAATAGGTCAACTAACAAAATGTGTTAAGCTCCACATTTTTGTAGTTAAACGTTTTCTGATATCACAGTAAGGTAGTTTTTGTGAAACCATCAAATCTGTAGGTTCTCCATTATTATTATCACCTAGCACAGTATTATTACCAGCTGATAAGTATCCGTCTTTTTTGGATGATCTTGTAAAGGAATATACCATTGTACTTCATCTCCTTTTTCTGTGTCTACCCTTATCTTGGGGTCGATCTTCTCCTTCCCGCATACGGTCTCCTCTTATTCAGAAAGTCAGGAGGAATATTCCGAGAAATTTTGTTTTGAACGACATGTGCGATCAATCGCTGGTCCAGAAGGTTTTCCCACTACTTGGCTCGTGTTCTCAGGTGAGTATGCGCCTTTAAACATTGAGGGTACTGTATGCACCATAACGCAGAATTGCAGATTCTAAAGTTGCGCAGGTTTGTTCTACACGGGATAACCGTAAAATTTTTATGTCCCTTTAATAGAAACTCGTCCGAAGAATTGGTAATGTACGTGGAAAACGACTTTTAAAAATGTTTTTTTACTCCAAACGATGCTCTATTGTGCCGAATCGCTTGTTGTTTAGCGGCGTTTTGGGACTAAATATTTATTTACTTATCGTCTTGTTTTTCATAACTTTATAACTGTTTAAACAAAATCGATAATATTTATTTCTAATACGATTCTGAAAATTTTGAATTCCAAAAAAATTTCGGATAATTTTTGATTTTATTTGGCAGATTATTTCTGATAGAATTTGAACACTCTCTTTGGCCAAAGAAATTCTGAAAGTTTTGAATTTCCCGCAAAAATTGAATTTCTGAGAGAATTTGAATTTCTTGCAATTTTTATGTGCAAAATCAATTGAAAATAAATGTGGTCGCCAAAACATAGAGAAAACTCCCGGCCACCGATTTTTTTTTCGCAAATTTTCCACCGCATTCTTTGCTGCATGACTGCCAAAAATTGGCGGCTTTGTATTCTACAGTGTTAATTCACAGATGGCCGAGTTTTCTCAGTTTTTTGCACGGTCACAGGCTTCTAGTTTATTATATTCATCTCCGCGGCGCGCGCACCGTACTTTCTCTCTACTCTCGGATCGTTATCCCTCTCTTCCAACCAACGCCCTCTGCGATTGTGTCATCATCTTTGCGATTTGTTCTGGAATCCCAATTTCCGTTTGGCTTTTCAATACCCGTGCCTTATTGGCTCAGGAATTTCTGGCCCGGAAATTTCCGGTCTACAATTCGGATTATTAACCATTTCGAAAAAAACATCCTTTAAATTATTTTTATTATAGTGATAAACGGCGGTGTGATTTTTTCTCGCTGGTGGGTCCTGGCACGACTGAAACTTTTCAGCTATGTAATTACCCAGCATTGCTTTAGAATTTAAATTTGCCGGCAAATTAGAACTGCAAGATTTTTGTTAGTTTTTAATTATAATTGTTTGGGAAAAGTACAAACTCATCTTTAATAAAACCCACCGTACTCCCATGTACTGCAGCCAAGAGACATAATTTGTTTCGTGCCAAGACCCATTTTTCCCTCCCTTTAAGAACTAGAAACCCCCTTGTTTACAACTGAACTTAAAATCGAATTAGTTTGTTCGCTAAACATGTTTTTCGCGCGAAATTTCGCTTTACAAAAAAGTTTTTCTTCATTCCGTTCGGTCGGCATGCGCCTTTAAGTGTAACTACTATTTTTGAAACCGACATAATGATAGAAAAAATTAGAAAATATTTTTAATTTTCGGCCGGAATATCTTCGAAAAAAAAACTAAATTTCATGGATTCTCAGTAAAAATTCACGGAAATTAAAACTTGCGTAGCGAGACCTCAACTATCACATTACCTATGCGCCTTTAAAGCTACCCTAACCCTATTTTTAAAAATAAAAGAATTTCCTTTTAAAAACGCCGGATTTTCTCCGTCTCTTTTCCCATCTTTTTTCATCTTCGGTACCCATCATATGTAGATGAGAATATCTCTGCACCTCTCCAACCAACCAAGTTCAACACTTCGATGCACCGTCCTTCAACGATGTGATCTTCCTCCTACTTCGACCCCCTCAATTCATTTCCGATTTCCTCGGATGTATTGATCTTTTTGCCTCTTTTATTTCTACGTTCTATAAAAGGATATAGCCAAATGGACTCAAACAATTACAATCCAAAGTTTTGACGTCAGTGAGCTTACTGCGAAAATCTGAAGAGATTATGTGAGTAAAAAGCGGCGGAAGACGTAAAACATATGAAATATTTTTAAAAAACTTTGTTAAAAGCCCCACATTTTCGAGATAAATCTAAATTTTCAAGTTTGTAGCAGCAAATCGCTAAGCAAAGATATATATTTCAGGCCGAGCAGACATAACAAAAATGCCGATGCTTCATCCACGGCATCAATCACTTATCGATGGCGATCGCCGTCACAGCGTCGAGCTCTCGATTTTTATTAAGTAATTTGTTTGCCTGCAACTCAGACCAACCAAATGCTTACGTCGTCTATTAGATCTTTCAACGATATTTGATTAGAATCTGAGAAAAAAGTATAATGGGGACATAATTAATAGGCTTATGGATATTATTTGATTTGACAATATGGATTTTCTAACCAAATATGGTTAAATTCTAATCCAATATGGAGCAAATCTAATCAAATATGGCTGAGATCGTGCCATATTGGATTATTTCGACCATATTGGATTAGATTTGTTTCTAATGAAATATGGAGAAAATCTAATCTCAGCCTTCATGAATTTCTAATCTAATATGGAGTACAGCAGCCTAATATAATGCAATATGGATTTAAAAAATATGGGTGAAGTCTCGTTGAATATTGTTGAAATCTAATTAGACGACTAAGCGTTTAGAGACAGAACTGGAGTTGAAAACCTTAAAAAAATGGGCGTAAAATTTTCAATTGTGTGGAAAAAATCAATGAAAAACTCAATCGTACAGTAATTCAAAAATTCGTTTCACTACTGGAAAAAATCAGTTCCCATTGAAAAAAGAAAAATCAATTTTTCCAGCTCTCAAATGGCAGTTGGGGCAATTCGAGCACTCGACCGTCTTCACCATCGCCGCCTTGCTCTTTCTGCTCGTCATTGTTCAGCTTTTCGTCGCGATTTTCTACCAAATGTACGGAAATCTTCTCATCTGCGACCGCACATCGTCATGCAGGTTCTGCTCGTTTTGTGCTTCCTGGCACTCACATGTGCGACGCTTTATGCGCTTTTCACGGTGCCACGTCTCAGGTGCTCGTCGTGGTTACAATCCGCAAATCGCCGCATTCCCTGGTAAGTGTGGTAAAAAATGAAGTAGATTTGTTTCCTTTGGAAATTCCTTCTTTTTCCTCAATTTTTCCTCATTTTTTTGCTTCCAAAAAAAAGACCCATTTTGCGAAAAAAATTGTTTTTTTAATATATGTCTTTTAAATTTTCCAGACAATTCTCCCGGCGCCAATGATCACAAAACGTGGTTTCCGGATTCTTAGTGGGCCTTCTCGTCATTTTCGCAGTCTCCTACATGCTCATCGCTGTGCTGAATGTGAGCTGTTCCCATGGCGACACCCATGTAACTTTAATTTTTGAAGACCTGGTGCAGTCGTCATCTATAGTTACCAGCTTTTGAGCCAGAATCAATCTTGTACGTCGGTCGAGATTGTGCGCCGAAGACACGATTCAACTCTCCCTATATCCCAATAAATCAGGCCACTGATTTTTAGTCTATATTGTGTAACACACCATTTGTTGAATTTTTCTCGAAAAAATCCGGTAAATTTTTGAGTATACATGTCCCGAAATTCTTCTTTTATCACATGTGTCAGGCTTTAATTTTCTTACTTTATTTTCGACTTCTGTACAAAAATCTTTGATATATTCTATTTATTCTTCTCAATTAATAATCACACGATCCATCTTTCCACTCGTCTCGCCACCTTTGCATCACATCTCGACAGTCGAACTTTGGTTTTCCCGTTTTTTCGTTGACTTTATAGTGTAGCTGGCACATCCATAGCGCAAACGCCTCGCGGCTTTCCACTTTTGGCGGCGATTCATTCAGATCTTTTATCTCTGTTGGCGCAGAAATCGCAGGGATATGTCTGAAAAATTTAGGCGTTTTTGTGTGAATCTTGAGCTTATTAGCTAACTTTTCCTAGAATAGAAATGATAAACTTCTGGCTCGATCCTTATCGTCTTGTAGGTTTTTCCCGGGTAGCGACATTGTGTGTAGCAAAACGCTTCCACATGGATCGCTATGCCTGAAATTTGAAATTTTTGGTGGAAATTTGAATTAAAAGCTTGAACCGAGCTCATCCTTGTTTCCTCTACTGGACATCCGTGCAATTTCGCTCCTGTGCTCGTGCTCGACGTCGATCTCGGATTCTGCAAAGAACTGAAATAATTGAGATTTTTTGCTCTGGAAATCTAGGTAAATCACATTTTTTCTTTATTTTTTCATCAGAGCCATTACTTCTCTGCCTTTTCTTCCTATCCTCTACACTGACGCATGCACGACACGGCTTCCCTCCATGGACCGATTTCCATTCTGAAATTTTTTAAGCACTTGGTTTTAGTTTCGTCTTTTAGAAGCCGTTTTAGGGCGTAAACTTATGACACTATACATAGACTACGACAAATCTATAGAAATGCATAAAAGATAGGTGAAAAATGTGAGAAATTGCGCAAAAACGCTGATGCAAAAACGAAAATAAATTAACTAAAAACATGAAATGCAAGTGCGCTCCACTGACACGCGTTAGAGAGCGTAGACGCAGAGAAATCTCGAAAAGATGAGGGATATCGTGGCGCGCGAGAATCAACCTTTTTTGAATTGTCTTGATATTAAAAGCCCAAAACCCTAATAGATCATTTTTGTTTTTGGTGGATTTTCTTGCTATGCAATGTAAAAATTTATTATTTGTTGCATCTAATCACTTTTAACAGAGATTTACAATTTGTGGCTGAAGGAAAATCCTTCAAAAATCAATTTCTACGATCCAAAAATTCGTTATTTAATTTTCCGCCCCGCTGATCAACTAAATTCTTCTATTTTATCACTTTATTGAAAACCCTCGCCCACCTCATTTTATCACCTGAAACTCGTCACACTTTACAATTTGTGAAATATGCGAAAATGGTTACTCAGCTAAAAAATCTGAAGCACGCGATAGCTTGCGACAACTTCTGGGAGTGGGATGGAACGAAAACGGCGAGAAAGGCAAATTTTTGGTGGAATTTAGCGAAAAAACCTGATATGTTTTTTTGCAGAAAATCGTCGCACGAGGTGCTTCGGAGCTTCTCTAGCTCTGGCCAAGAGCGGAGTCATTAAGTGAGGATAACCAGGAGATGTAGGATTTGTATGATTTATTTCTGCGCGTATATTCAACTTAGCTAAGAAAGTTTGTTTTTTTTTTGTTAAGAAGTCGTAAACAACTCAAGGAAATACCGTTAAAAATAAGCATTAAATAATATAGAGGCTTATGAGAACAAAAAATTCCAGGAAAACGAAGAAGCCAACCAACAATTCGAAAAAGAACGAAAAATGGGCACAAGACGAAGCGAAAAACCAGTCCCAACTCCACTGTTCGGGAGCTAGCTCAATACAAGATGTGCCAAAACGTTGCTGTCAGCAGGGAATCGATCATCTCAATCAGGTGCCATGATAGCATATTGTCTGAGACTACTTGAACTTCCAATCACAATCACCGAGAAAAATCGCACTATAAACGAATATGATCCAACGTGCTCCTAATGAGCTCCAACTCCTCACAGCGCCATTGAGCCGAGCATGCTCATTTGAGCAGCTTATGAAGAAATGGATTTGGAGCCGTGTCGAAACTTCCGCCGATATGGGGGCAATCGCGAGAAATTATATGGAATTGGCGGCGAACTTGCTGGAAGACGTGGATTCACCCACGTGGTTTTGAGAAGTCGCCTATTGACCTGATGGCGAAAGTGATGGGAACACTGAAGAAAAGTGTGGAAATGGATATCCCAAACAATAGTGCGTGGATATCTTGAAATAATGTTCAAAAAATTCAAATTGGCTTGTTAATGAATTAGGCTTAAGCTTAAGCTTAGATTTAGGCTTGCATAGGCTTACAAGTGCGGAAGTATTTCATATTCCCGGACTACAGAATGAAACCTATGTCATTTCGAAGGAGACTCTTTAAGTAGGTCCCTTCAAAAAATTTAGCGGCAGAGGAGCACTTTGACCTGGAAAAAAGTCGCTCTGAAAACTTTTCAGTGCATTTTATCACGGTCTTTCGAGGCCTGTAAAATGGATCCAAATGCGAATTTTTGTAGATTTTTGAAGATGTCTAGGATGCTGTCGCAGAGCACTCGGAACATTTTTTTTGGAATTTTTTAAAATTTTCGAACTGAAATTTCTTTTACTGTGAATAAGTCCATGGCAAAATTTTTCAGTGTATATATATATATATTTTTTTTAATTCAGAAAAGTTGTCAGTTATTTAAGATCAAAATGGGTGTTTTTACACAATGAATATTTTTTTGAGATTTGATTCGGACCTGCAAAAACCAATTTTGGAAAAAAATCGGCGTTTTACCCGGACTCGAACCCCAGTCTTAAAATATATTAATCAAACTCGCTAACCACTCGGTCATTCATCGACAATTTTTCTTGTAAATGAAATGGATGACAAAAAAACGTGACTCATTGATATCTACTTAAATATATAGGGACGTGAGAAATAGCTTTGGAAAAGGAGAGGACGAAGAGAATTCAGAGAGACTTTTTCCAGTTCAAAGTGCTCCTCTGCCGCTAAATTTTTTAGTAGGGGCCTGCTTAAAGGGTCTTCTTCGAAATGACATAGGTTTCATTCAGAAATCCGGGTTTAAGTTCTATTGAACTACTTCCCTGGTTAGGCTCACTAGGGAGTGACCAGAATAAATCGATAAAAAATTGTATCGGAAAGCTGGCATTCTCTACTATAAGAATATGAGTGTTTGCCCGTTCGGGCTGGAAATCTGAAATTTTTACGTCGGAAATTCTACACTGAAATCAGTGCTTCCTATGGTTAACAGTGGATTTTTGTCTCTGGAGCCAACAGAAGTCTCACCACAATGGTGGAAGGGCGAAATCCACATCGGTTCGGTGGTCGAGCGGTGAACGCGTTCGCCTCTTGAGCAGGAGTTTGTGGGTTCGGCTCCCATAGTCATGGGTTAACTTTTAGCCTTTTTTATACAAAATTTTCAGAACGGGAAACAAGTATTTAGAACATTTTTTTGAGGGTTTTACATAATTTTTTTGCTTTTTAATTGACCCATAATTACCCAGGAAACTTTTCAGAAATTTTAAATTTACATTTTCGAAAATTGACTCTTTTTCCTCCAACTCATGAGAAAATATGATCGAAAAATTTTTTTTTGAAATTTTTTTAAAAATGCATGGAATATTTTAGAGTGTCACAAATACCTATTCATTATTACGTTTCAAAGACCAATCATTGATTTTCTGATGCCTTATTAAGACGTTTTACCAAATCGATCTTTCAGGCAAAACATCTTGTATTTGAGGTTCCATATCTCTGCAGTAAAAAATCGCACTCAAATGTGATCAACTAGAAACTTGAGTTAAACACAATGTGATCTAAAACATTTCAGGGGGTTGAACACTTTTTTGTAAAAAACTTCGTTGCCGAGTTGGAACCAATTGATTTGAGATTCACTTATTTTTGAATATTCAAAATATTTGTTCTATATCTTGGCAACGAAATTTTTTACAAAAAAGTGTGCAACTGAAAAGTTTCAGATTACATTGTGTTGTACTTAACAGGTTTTCAGTTAATCACTTTGTAGTGCGATTTTTTCCTGCAGATATATGGAGCCTCAAAAACAATGTTTTGCCAACATCGATTTGGTAAAACTTTATTTCATTTTTTTTTTTCATGTTATTGTTTTTATATTGGGTCAAAACGTATTTGCTCTGCTATCACAATAAGCTGGCGCTAATTTTTAATTTTATTATTTTCATTTTGATAAATTTCACTGAAATTGTCACTTTAATGGTTTACATTCTATTGGTTTTCTTTTATTCAATGTCTTTTGATCGGAAACGTGATGTTTGCCTTGCATGACCGTCATTTTCCTTCCCAATCCCCTCCCATCAAATCCCTCGATTTCGAGACATGAGCAGAAGGTGGCAGATCATTTGGCAAGCATTATAAAGGAATCTTATCTTATGTACCAGTGTGGAAGAATCCGAATTTGGTTGAAGACGAAGAATATGTCGATTGGGAGCCAGAAGTTTTCAGTTGAGGTATGTTGGTTTCGACTCTATTAATTGTCATTTAAAAAACCTTTCAACCGTATGACTGTGTGTTGCCGGATCAAGATGATGTATTGTTCGGTGAGAAAGCTGTATCAAGGGAAGAGTTGGTTAAAGACGTGCGATCACCGTTCTAGCGTAGAAATTGGAAGTAGGCCGATAACGACTCTGCACCATAGTTATCGCTGGATACGAACCGATGCTCATATGTACAAACTGCGGAAGTACGGGAAAGATAAAAAAGCGTTCCAAGAACGGCTCGTTTGGCACAGCTTACACAGGCTTTATGGCCTTAGGAGGTCAAGGTGAAACTGAAATGGTGTACATTAAAATAACAAGTTTTAATATAAATATTTTAGGGGTCTTTGCATGATTCTGGTTTGATGGCTACGGGACTGGAAAACATCACCCGCGAAGTGAAGTTAAACAAAACGAAATGAAGTTGCAAAAAGGTCCGTCACAAACCTGGATAACCCGATGTAAGCAAAGCCACAGGAATGTAAGAAATTGCACTTGTATGTTAGCTATATATATATATATTTATATAATTTCGGAATCGTGAGTCGGAGAGTCGTACCAAGTACATGGAAGTGCCAGATCAATAAAGACGCTAAAAAAACGGGATGATTTTGTCAAGAATGCCAGAACAGAGATCTCAACCAACTATCACCCGTCGATGGTCTTCAAGTGTGAGCAAACCGGAATTCAGAAGGAGCGGTATCCAGCTCGGTCATTAGCCCTTGATGGTCGAAAAAACAGTCGAGATGTTGGCGCACCTCAATCGAAATCGTCGCTGACCCACTCGTTTACGTTTGTCCCGATGATTTTACTCGATGGCTCAATGGGACCCCAAGTTAAGGTAATCGCTGATCGACTAAAAGGCCAGTTTCCTCCGTCTACGTGGTCCAATTCAAAACTGCCCCAATTTTGTGCGGGCTGGATACAGACACACATCATGACGAAGCAATTGATGTGCGATTTTTTCGAATGTTGTGTCTTCATTCCGTCTAATGTGACCGAAAAAACTGTACATCATGCTGGACCGGCCAGCGTTCAAGGACCATACACAAGAACCTGGTTCCAAATGGTCATCATGTCGTCATTCGCAACATTCCAGAGCACACAACTGGAGATGATCCAACCGTTGGATGTCTATTGGGATGCGCCATGGAAGAAGGTATGAATTTTAATCTTTATAACTTTTTGAAAGTATTGTCCAGAGCTGGTGAGCTGCTCAAGAAGTTCACAGCATGCATGCCCTTCGAACCCAGACGGATTACGTCCTCGAGGAACAACCCAATTTGCATGGTATCTGTGTTGTATCTCCAGATCTCGGCAGTGCACTTCCGACCGTTACAGCTTGAAATCGTTGGAAGAAAGCTGGATACGTGGGTGCTGCCAATACTTCATCAACCGTACCACTTTTTGACTCCAGCTCATGCCATATTCCATTGATCATGGTGACCCAGTGATTTGCTATCACACTTATGGGATGTAACCATCACGGAGTCATCCGATGCGCAAGATGCAAGATGTTTGTTTGTTCTTCAACCATTTTGTGGTAACAACATCTTTGTTCATCTCCTGAATAACTAATAAATTCATGATTGCATTACATTCAAGTTTCGCTATGACTAAAATTGTTTATAAGGGGATACATGGTTGTAGTGGTCCATGGTTTAGTTTAAATTGGAAAAGATGTTGAATGAATCATTATGGTCTTGGTCGACACATAGATCATGCTGATGTCGATCAGAAAAATTAAAATTTGGGTTTTTATAGTTTCGAAAAAACACGTTTAAATTTTTGAAAAACTTTACCGTTCTTTAGGGTGTAATTGAACTCCAGATCCCACCATGCATGTCATCCACTCAATAGCCACTCGGCCATCTCCTGTTGCAGGCAGTACTAATTGGGGAGGTTGATAAGTAAAGCACGTCCGAATAATTTCAGACGTAAAAATATCAGATTTCCAGCCCGTACGGGCAAAAATTTCAGTCATTACAGCAGAGAGTGTCAACTTTCCGATACAATATTTTTTTTTTGAATATCGCTCTGCCATTTATTCTGGTCATTCCCTAGTCAGGATCAGCTCTACCTCAGGCCTAGGCTAAGCATAGGATTAAGGGTAGGCTTTGGCGTAGGCTTATGCTCGACGCTTAGGGGCTTGCTCAATCATACATCTTGCTTAAGCACGCAGCTTAAGACAGCAAAGCTTAAGCACACAGATTGGGCTTAGGCTCAGGCTCAGGCTTAGAAACAGTCGAAAAGTTAACTAAGTCAAAAAATTTTTTGTTAAAAAATTGTTTAAAAGGTATTATGATTTTAATAGAAAATTGGAAAAAACCCGAAAAAAAATGAACATAAATCAAAAAAAAAATTTTTTTTTAAAGAAAACTTCTTTTTTTCGAAAAAAATGCAATAAGGTTTTTCTGAAAAAAACAGGACTTTGATTTTACTGTAAAGAGAATTTTTTCTGTTTTCTTTTTCCAAGATTTCAACTTATTTCTGCGCTTCGAGTTTTTTTTTCAAATTTCCTCTTATTACAGTTGGTTACTGTCGAAAATTCTCGGTCGTCCACATTCATGACAATATCGTACTGGGGTCTCGAAGCGAGAGATTTCATTGTTCGTGAGATTTCTCACAGGTAGTTTGTCCAACTGGATATCAGTGGCTCATAAGATGCAGCTGGAGAACAGTCCTTTGAGTTTTTTTTCGGAGTTTGCAAACGCGCCCTAAAAAAGTTTGGAAAATTCCACGTGGAAAATAGTTTGGCGAAAGTTTTGATACAAATTTTTCGTGGATTAATTTTTTTACTGCTCGAAATTCTCTTTTGTTAAAATTAAAAATGTTTTATGGGCGAATTATTTTTCTAAATTTCAGCTTTTCTTTCACCAATAAAATATTTTTTTGAAATATCGCTTCGAGACCCAAAAAAATAATTATTCAATGAAATATCGAAAACAGCCAAAATCGAGAAATTATCGAAAATAATTCGAAAATTGGAACTTTTTAAAAAATATTTTAAATTTTTTTCAAATCAACACAAAGTCTCTCAACTTTTTTCTAAACAAGAAATATATTTCGTGACGAGACCCATTTCTACTAATTTTCTTTTTCAGAAATGCATAATGCGTCCATTGGATTGATGATCTCGCTTGCCATGATCGAAACCGTACACGGCCACCGTACCATGAACGAAGTGACACGTAAATATTCGAAAACTCGCGAAAACCGGAATCCAAGAGTCTCTGAAATTGGAGCACGTAATTTCTCAAGGAGTTCGACATCGATTCTCTTTCCGAAGAATGCGTGAGAGATCTGACGAGATGGTTGATGGCCGAACGATGACTTGAACAGCCGTCTGCGGCGATGAATGAATCGTTTGAATTGACCGTTGATAGCAGTAGTAAGAAGAAGGACGATGCCACGTTTGTTAGTGCGTACATAGAATTCTACCAAAAGGAGATCTACAAATTCTAAAGAAAATCTACGAAAGGAGTTGTCACGGCGCATGCCAGATCGATCTTTTTTCGGCTCAAACTTGGAAAAACCTGCAATTTTTATACATTTTTGGCTTCGAAAAGCAGGGAACTCTGCAATTTTAGGCCTTTTTCGCTAAAAAATTGGAAAAATCTGCAATTTTTATACATTTTGTGGCTCACAAACTGGAAAAACTTCCAATTTACATCTCAAACAGTCGGGAATCCGCAATTTTCCTCACATTTTTAGCTTAAACTAATTGAAAACATCTGCAATATTTCAGATTTTTGGGTCAAAAAATCGGGGAATTTTGCAATTTTTACATATTAAGTTTAACAGTGGAACATTGCAGAAAATCGGCATAATGTTGAACGTTTTCCTTTTTCCAGTTTTCTGTTTTGTTACGATTTTCGTTTTGCATGGAAAATGCTTCGATTGATACCCTTCTTTCGGAAACTAACCGACAGGAGTTTCTCCTGAAATAGGCGTAATCTCAAACCATTTATGGGCGTGGTCTTCTCTCTTATGGTTTTTATAAATGTTGTTCATTAAAACATTTTCAGGCCTTATCAATCTCTCCATTGGCTCGACGATTTCCGGAAAACATAAATTGAACGCGGGATGGTGTAATGCAAATCCTGAATGAGTTGCTAAAAAGTCGACGACTCGAACCTACCTTCACGTCACTAAAAAAATCGTGACAATCCTCTGGGAAAAGCGAAAATCCAACTGAGCCACTCCGTACTGTGTTCTGCTCTACTCTCCACGTCGTCTGCCAGGCCGATGTTCGATTCGCTCATCGGAAAGTGCCGACAATCAACTCGATTCTTAAATATTCGCTGTCTCTAATGCCAAATGTCGCATCTCTTCCTAGTGACGCTGCGTGGTCCGAAACGATTGTCAGATTCAGGACAGTATCACCGAGAGGGTCTCCGTAACACGTGGGATACCGTATCCCGAAACCCGCTAGCTCCGGCTCATAGTGCAGTGTTCGGCTGATTTCGGCATTTATCTCCGTTACGGAATTTGATGAGAATTCGAGATTCGCCAACGATGAGAGAGTTCGGAGTCTCAATGGAGGTAAGTCACTTTGCCACGTGGATGGATTTCCTTTAAAAAGAGTTTTTGGAAAACAAATCAGATTTTTGTATATCACCTTTAAATCGAGAAATTCTTGTTTTTCTGTAGTTTTCGAAAAGACATAATAGAATGGGTATTGCGGGAACTCCGGATGCACATAGTCACAAATTACTCTTCAGTTGTGCCTGTATCATCCAACGTATGGTACTGTTTCAGAAGCTTCTTCTAGTGTAGTTTATACCGTAGGGCTTCCAATTCTGGTAGAGGCGCGATTTCAGGGCCTGACGCCCGCCTGGAACCTGCTGACCTTTCGCCTCTTTTCTCTCATTGCTAATCAATTTGTTGAAAATCAAACTAAGAATTAAAAAAATAGTTCACGGAGCTTGTTCTGTCGTGGATTGGGGCGAGGGGCAGGTGGTGGTGATCTTAAGGTCAGGTAGGCAGGTGTCTTTTCACGCCTGCATTGAAGTCTAGTACCCCATATGCCGAAAACGCTGAATTTTCTCATTTTTCCAGACGACTCCCTGCTTCATAACTCTGAAACTAAGTAAATTAGCTTGCTCTCCAGCTCCTCCCCATCGGCTCCAATAGCCCTCCGAGGGGGCCACTTCTCGAAGAATTGAAGAGATTGGGAGATATGTGCATGGCTAATCTCAAGAGTATGTGAGCCTGTCGTTTTTTGATTTTTGAATATTTAAAAACCCAACATTTTCAGCGACTGATCACTCAGCCTCATTTGTGCTATGCCACGGATTTGCTCTGAAGTATCTGGATAGATCTTATGAGATTAGTTCAGCGGTTTTTTTTTCTAATTTTCGAAAAATTTAAGAAATTTTAGGAGCAATTGAAGAGAGAATTTGAATTTTTAAAAAATTTCGAATTTATGGAAACAGTAAAGTTTTTCGGAGTTTTTAAACGAATTTTCAGAATTTTGTAATAAAAAAATTTTCTAATTTTTATTCCACAATTTACAAAATCTAAAAAACTTTTTAGAAATGAATTGTTTGAGAAGTTAGATTTCCTAATTAAAAAAAAATTTGGGTTTTTATACAATTCTTAAAAGTTTGATATTTTCAAATGATATGAAGTTCACACATTTTTTAAAATATTCAAATAAAGAACATTTTCATTTTTTTGAAGAAATGTTCAAAAATTAACATTTTTTGAGACTTTCAGAAGTTTCTTCTGTTTTTTTTGCGTTTTCAAGTTTTTTGCAATTTGCGTAATTTTTATGGGGGACAGAAAATTTTGAGAATGCGGATTGCACAACCTTTTTGACGCGCAAAATATCTAGGAGCGAAAACTACAGTAATTCTTTAAATGACTACCGCTAAAATTTAGCATAAAAATAAAAATATATCGATGTATCTAGGATCCCGTAATAATCGACAGTAGCGCGCTACAGTAGTCTTTTGAGACGAATTACTGTAGTTTTCGCTATATTTTGCTCGTAAAATGTGCACGAATTCTTATGATATTTTGTTCTCACAAAAGTTGGTCAATTTATGGGATTCTCAAATTTTCGTTTTTTTTTGAAATTTAAGATTTTTAAGATAACATTCTTCAAAAAACTGATTTTTCTCTTAAATTGAAAAGGTTTTTTGAAAATGTACAAAAAGCTCTACTGATTCAAATCATGGAAGATAAAGAAAAAGACGAGTTTCTCCAATCTGCTCGCCATTTCTCAAAATGGCCTCAAAATCTGACACTACCAATTCAAAAACAGACACTAAATTGGCATGGCTGTCTTTTGCGAAGCGCTTGACAGCTCGTCGATCTGGTCTGTCAGTGGAGTGACCGACGATAAGTGCTTGTCGAGATGCTCGCCGAGCTGGCTGCCACAAGCTCTGAAATTCTAGATAAAGTTCCAAAATCGATGCCATTCAACAAATTCGTCACGGAGAGGATAATGCAGAATCGCGGTGATTTGTATGTACTGACAATTCGAGAAATATTCGTTTTTGCGTCTCGTTTCGGATAATGGCTACTAGGATGCTTATAACATGAGTGTTTGTTCTTGGGGATTGCCACGAAAAACTGGCAAAACGTTTCGAAGATTGAAAAAATATTTCTTGCAACATTATAAAGGAATTCCCATTTATATAATTTTGGAAAGTTTTTAGATTATATTAGGTAAAAAATTCGAATTTACAAAAAATTATGAAATTTTAAAAAAAAGTTTGAAAATGTATTTTTAAAAAATTTAAATATTAGTAAATATTTGAATTATCTAAATGTTTGCGATTGTGTTTTAAAAAAGCTTAAATTAAAAATTTTTTTCACCATATGAATAAATTAAAAATATATAACAAAAATTCAAAAAAAATTTTTTTCGAGAAAATTTTTTGCTTTTTTTAAAAATAGAATTATAAAAAAACTGAATAAAAACCTTCGAAAAAAAAACAATTATTTTGAAATTTTCAAAAAAACTAGCAAAATGATGTTAAAAAATTTGAGGAACAAAATTCACATCCCTTGCAGAAACGAAGCCGCCCAACTCCTAGGAGATGGTGAAACAATCAGTGAAACCGATATCTTCATGAAATCGAAAAGCGAATTACTCTTTCAACGTGTATTCGTAATGTGCCGTTTCCGAAGCAAGAGTAGAGCGGTTACACACTGGACCCCTATACCGCTGGGGAGCGGCCAACGTGCACAATGTGCTAATTTAAGCACGATCACATAAACGTCGAAATCAATCAGGAATTGCTGGAAAAGTCGCTATTTTTCGCAGAACCGTCATTGTCCGCCACTTGTTACGGCAGAATGGAAAAGAAGCAGAACCTGATGAGACGTGTCACTGCCCCTGTGCTGAAAATTGTGATGAAAGATGAAAAGTTGCTGGCGGCAAGGAATTTGGAAAAACTTGAAAAAAAAGAATTTCATCGTATTTTTAAATAATTTTTTGAATGAAAAATTCGGGATTTTTCCTTTTCCGCATTAAAAAAAAATTCAACCTATTGACTTATTCGAATTTAATTCTCAGGTGAATTTGTATTAACTACTATTTTCATAGTATTGGCTTAGAAAACAACAGTACTAAGCCTTAAGGTGAGATACAGATAAAAGAAAAAGAGTCCACGTTTTTATCAATGAAATATTCCTGAAAAAATTTCGGCGGGGTAAAAAGGAAAAGTACCAAAAATCAAACTTTCAAAGCTAACAATACGCAAGTATTCAAGTTAATTTTAATAATGGTTTAAATCCGGAATTAAGAAAGTGGTTCAAATGTCATTTGACTCATCCCTATTGTATTGACAATTGAAACGATTTTTGAGACTTGTATTTATTTAAGGAAAAAAAGTTCAGCTGTCACAAAGCAGGTCGTAATTTTAATTTGAATATTTAAAATAAAAAACTTATATGGGTGCTTCATTTTGCAAAACATTGCATTTAAAAAAAAAATTTTCAATGTTCGGCAAATCCGAGCTTGAAAAAAATCCTTCTAATTGTGTTTCCGAATTTTTGGGATTTTTTCTTCGAAAATAGGAATGGTTTAAAACAATTTGAGTTAGATATTGTTGCATATTTTTTTAAAATCAATCTCTTGCAATCAAAAAATTGAAATTTTAAGCAAAATAATAAAGTTTTATCTAATTTTTCAATTTTCAGGTATGGGTGGCCACAATTCTAAATATGGTTCGATCTCTCAAAGTCTATCAGATTCATTTCAGCCCGAAATCCAACGCGGCGAAGTTCTTGTAGGTTTTGTTACTGCGAATATCAAAATTTTGCTCGTCTAATTTGACGCCTGCTCTGTTTTTTTTTACGCGCATTTCAAATTATCTTAGAAATCCGTGACTTTCGTCTAATAACACCATTTTGTAAAATCTGAGCAATTTTCGGTTTTTGCGCGTCAAATGTGAGATATCTAAGTCAAACTTGACGCGCAAAATTTTCAAAAAAAAAATTCAATAATTTTCCGGGCGAAACACCTCGACATGGAATCGATTTCCCACTGCCAAGCATTGCGAAAACAGACGCAACAAAATAATCTGATCACGGCCGCCAACTTTTTGACACTTTTCGGATGTGAAGCGCTCGAGGTTGGAAGCGCCTGATTCTCAGATTTTGGAGCACCGCATTTTCAAGCAAACCGGCTACTGTGTTGCGAGGAAATGCTCATGCTATTTTTGTAAGCAATGATTTTTTGATAAGAAATTTCCCAAAAATTTTGATTTTTTGAATTATCTTTGTTAACTTCTTATTTTTAACTCAGTCTTTTTGCAAACTGAAAATTTCCAATTTTTGGGAAAAATCTCCATTTTTCAGGCTGAAGAATGTGTCGAACTTGGCCTGAACCACCGAATCGCTTCTCTTTTACGCGCACTGACAACCAGTCAATTCTGCCGAAAAGCTCTATGCGATGAATCTAATATCTGAAAATCGCGTTCTGACTTATCGATGGATTTTTTGATTTAAAAATGAGTGCAGGTTGGTGGAGAATAGTAGGATATGTGGAAAAACAATATTTGAAAAATAAAAAAAAAACTCATTGATTTGAATTTTCAAAAATTCCAAAATAAAGAATTGTATTCCAACTTTCATGAAAATGGCAACAAAAAACTCAAAGTTTCCTTGGAAAATTTTTGAAAGTACAAAAAAATTAATTTCTGAGAATAGTTTCAATATCAAAGTCGAAGTTTAGTTTGAGTAGTGTTGTCAACAATTGCCTATTAGAATAGTTGAAAAAATCTTGGAATTTACGAAAAACAATTTTTAAAAATTTCTCCGTCCAAATTTCGAAGCAAAAAAAAAGTCTTCTAATTTTTGACATTGAACAATTTGGAAATTTTTTGAATTTTCAAGAGTAATTTATATTTCGAATATTCAGAACAGTTCCAAAAAAAAAGTTTTGGATTTTTTTCCAATTTTAATAAAATTTTCAACACAGAAAGTTTTTTTTTAATTTTTTAAATTTCAGAAAAAAATTAATATTCATAAAAAATTGAAAATTCATCCATTCTAAAAATAAGTTTTCACATTTTTCCCAGAAATTGTGGAGCTCTGCTATGACATGAATACTTCGGAAGGATCTTCTCCAGCACCACATCAAACTTGTTGCGGCTCACCAGTTGGAGCACTTGAGCGTTACGAAACGAGACTCGTATTTTCTGTTGAGAAATTTCTGAAATCTGGAATTGATGGTATCGATTTTGAAGATTTAGGTTTACAGTCGAGTTTTATAAGCCGTTGAACGAAAATTTGACAAGACGCGATCAGGAGCAATGAGGCGAGAAGTAAGGCCGTGGAATATAAATAGGTGGCCGAGTTTTTTGTAAACTATGCCACCAAACTTGGTTTCTCCGTTCGTGGCCACAAAAATTTTGAATTTTTTGAGCTTCTCTTATAATGCTTAAAAGTGATTGCAAAAATTCATTTCTTTAATTAGAAAACTCCAAAAAATTTGAAAAAAAAATGTAAACTCAATAAAAAGTCCAATTGTTTCACATTTATTCTGGTTTACTGAATTATCAGATTTTTTCTTCAATTTTCAGTTTTCGACTTTTCAAATTTAAAAAAAACCAATTGTTGCCCGAACAAAAACCATTAAAAATCGACAGTATGTCATCCAATTGGGGTACAAAAATTTTAATGTCCAAATTTTCATGACGAACGAAGAAACCTCGTTTGGTGGCCTAGTTTCCGAAAAAACTCTGTCACCAATTTCTTTCAAAATTCAAAATTTTAGTGAATCCCAAAAAAACGAACATATGCGGCGAAAATTTTTCAAAAGCTTCCGAACAAAATCTAAAAACGTTCCGAAAGTTCTGGGTAATTTTTTAAATATTAAAAAAATTCATCATAAAAAGGGCGGCAGATAGCGGTTCAGTCGGTAGTGGTGGCCGCTAGCAGTCTGGACGAGTCAAGTCCGAAGCCTCACCACCTAGGTTCACCCAGCTTCTATTGGGAAGTGGAGCAATCCACGACTGGATTATCGGCCACCCGGCTAGGACGTGTCGTGCATACAACCTAGCCCGAACCACCAGGCAGATTGTACCAGGATCCCCGATCCGATCCAGTGCAACTTGAAGAACGGGTCGTCCTTTAAAGATTCTTTCAAAACTAATTTTTTACTAAAAAAAATTTCCAGACATTCGTCGACAGGGCTTCCTTCTCAACAATTTGGCTCCAGCTCTCAATCGCTTCGTCCCCAAATTCTACCGATTCTCGCCCGCTTCAAGCACATTTCCCCAGCGGGGACTAATTTCCCCGGGCACAGCCGCCTCATATTTCGACAAACGAGATATCATTTAACTTCAACATCTACGATTTCATCTTTATTAGATCTAGAAACGAGGTATGAATATCCGAAATCCATGAAGCAAGGCGAGTATCCACGTGTATTATGATTGACGAGCTACGACTCGAGCCATTTCGTTGCTGATAGAGAAAAAGCAGCTGGGCAAACTGAAATTGCAGCAGAGAGTGAGGAATGTTTTGTGCATTTTGAGCCGACTTTTGAAAGATCAAGCTGTGATGGGTAATGAAGATGAGACGATTATCGATCCGATTCTTTGTTAAGGCAATCACCAAAGCTTGACCGTCGTTTTTGTATGTTTTTATACGACGGAAATCACTGAATTTCATGTCTATGCCGAAAAATCATGAGCAAGTATATACATCACATGAAAGAAAATAGTTACAGGGCCGGTTTTTTAATTTTTCTGTCATACCGGCAATTTTGAAACTACTTTTTGAACTTTTTAAAAATTTGGGTAAATTTGGCAAGTGCAAATCTCTGTATCGATTTGTCAGAATCATAATAGTTGTTTTAAATTGAACATCGCGTTAATGTTTTTAGCATTTTATCTTCGAAGATTTAATGTCTCGCAGTTAAAAATACATCTTTGCAGGAAGACTCCGCCGCGTGCATCGTACCATTTTTGTTCAAAATTTGCTCATGGGGACTTCAAGGTAAAATACGATAAATGTGTGATAAATTTGCTGGGATGTCTTTAGGGAGTTCATGCAGGTATGATTTTTCGTCGGAAATGACTGGAACGCGTTTTGTTCGCATCAATTCAAATTTAATGTAATGGCATTTGGCATATGAAATGTCGAAAGGTGCTGGGAATGCCGAATAATATAATTTGGTATGGAGAGCTGAATAAACTAGACAAAGTTCAAATATTCACAACACTGGGGATTGCTTCACCCGTGACCCGTTTAACCCGTTCACCCATTTTTACAAGGGAAGGTTCTGAACTCGTTATCGGACTTTACGCCCCACTATATTCATTCGATAGAGAATGGTTACAGATGATCCTCAGACTCCAAATTTAGCTGCTTCAGAGCAGGTTCGACCAAGTTACGACACTTTGAAGATGCCGGAGTAAAAAAAGAATCATTGATGCACCCCCTTTGAAAAAATTTCACGATATTCACTGAAAATACCGCTTTTTTTTTCTGAAAGTTGATAAAAATAGTTGAAATCGATTTAAATAGTAAAAAACAAATAATATTTTATACAAGTTTTAGCCCATCACTCTAAAAAAACCCCGTAAATTAATGTACATATCTTGAGCGAAAAATTCCAAAAAGTGATGTTCATGTAGATCCATCTAAGCCTGGAGCCAAGCCTTATGAACTGAAACTTGTATGGTATGACATGTTTCCATCATTTGCAACTATTTGTAAACATTTTATATCAACTTTGAGAAAAATTATTTTATTGAACTTTTTGGAATTTTTAAAAAGGGAAGTATTTTGGCACTTTCAAAATGTCGTAACTTGGTCGAACTGCTCTCAAGCAGCTAAATTTTTTGGGATCATCTTAACTAATCTCTAACTAATATAGTTGACGAAGGAAGTCCGATAACGAGTTCAGGGCCTTGCCACCCTTTTTAGGCGTCTTTACGGGTGACGGGTGACCGCTCGCCCGTTTTTTTTTTCGTTTTAGTTGTTTTCACGGGTGACGGCTGGCTCGTCACCTGTTTTTCAACCGTTTTTGGAAGTTTTCACGGGTTATGGGTGATCCTTGGTTCCGGCAGCCAGTTTAGGTAATAGGTCGTAAATATCGTTTTGGGCCGCGTCTTTACAACTGGGCTGTGTGCAACTGGGGGTGCACTTGGGTTGAAAAGGATCGACCGGCGGTTCAACTTTAGGTAGCATTTGGAGCGACCCCGATAAATAAAATGCCGACCCTGAATGAAAAATTTTAGCAAGGCGGCCATGCTCGTTTAATTTCCATTCTCAAAATTATGAGCGCTCGCCGGACTACTGGTTGAGCTATTGTGAAACGGGTCGACCCTGCTCGACCCATGAGCACCCCTGGCAACCATGATTTTCGGCAACTGGCAATCAGAGTTGCCGCACCCAATAAGTTTCGGCAGCCGGCAATTGCCGAAGCGTTGCCGAACTCTAAAAAGTGCAACCGCCACCGGCAATTTTGCGCAGCCCTGGTTTACACCTACCTGACGACTTTTGGTAGACTAGAACACATGTATTCGAATTCGACAGATGCAGCCGAATGCCGAAAAAAGTATTGAACGACATTAGGCACATGTCCGGGATGGGCGGATACCTTTTCGGATAACCATCTTCACTAAATCAATTTATCAATAAGTATTGATTTAGCTTAGTCGGGAGATACTATACTGACTAGAATAAAGAGTACCTATTGAGCAACATGTTCATATGACAAAAACGTTTAAAATTGTACGCATTCTCCTCGAACCCTGAAACTTGCCGTTCTCTGATCAAAATCGGCTAAGAGAAAACGGACTTGCATACTTTTTATACGGCAAATGTGTAGAATTTTAAAATGAAAGATTTGTGCTATCAAAATGTTGCTCACCAGTTTTTGTTCTCCCGGATGCGCTTCTTCCAGAATTACTACATCAGCACGTATTGATAACTAACTTGAGGTGTTTAATGAAGTTACCCGAAATCCAAAAGTATCCACACCCCGTCATAATAAGCATATTTCATAAGTCAAATATCAAATTTACTGAATTCCGCACACCTCTGCTCTCCATGCTCCAACTAATTTTTATTGCAGAAGACGAAATAGTAGTCCGCTGCCTTGCCGAATTCGTCGACTCTATTGGACTCAACGTGATTGCTGCACGCGTTACGAAGGCCTGAACATTGAGACTCATATTCGCAATTCGGTGTGAAATGGTTCTTCAAATTATCCCGTCTCTTTCTGAAACATGTGGATTTACTACGCATTCCTTCGCGATTGCGAATATATTATTTGACCGACTTTCCCAGGGCGAGAAAACGAAATACAATGATGATTGAGATCGTACGAGATTAGACCGAATTGATCACAGGAACTTATCAATCTTTTGGTGGAGATCTATGTGCCGAGGGTAACTCGGTAGCGTTGTCTTCTCTGCCACCTGCGGTCCAATAGACCGGATGTTGGGCAGGTTATGATTAAGAGTTCAAAGGAATGTCAGTTCAAATTGCTCTCTTCGATTCAAATGAGACGGAGTTGACTATTGTGCAGTGGTGGTAATTGTTTATTTTGAAATTCATTAGAATAGAAAGCAGTTTTCTTGGAATTTTCAGGAAATTAATTTTTTACCTATTCTGCATTACTAGATTCTTCAATTTTTTGAGAAAATATATATTCCTTCGAAAAACTCACGTAACATCTTTTCGTATACAAGAAGAAAGTTACAGTCGACGACTTTAAAAAATTCAGTTAATAAGATTTCAAAAACAAATCGAATTTTTTAATTTGTACCGCAATCTGGAAAATATTTTAAAATGACTCCAAATTTTTCCCTGATTCCAAATATCTATGAGATAAAATTCATAAAATAATCCCTTTTTGATCTTGAAATCGCCGTATTTCACTTGTGCACGCATGAGATTTCGAAGTTTCGCGCCAGAGACCGCATGTGTTAATTTACGAGATTTGTGTATATTTACGAACCCCTTAAGCTTTATCGGTTGCTGTTTGCCGTTTTTCAACGAGTTTTCTTCAGTTTCGTCGGTTTTTGTTAAAGTTTTTGTTTAAAACATTTAAAACTTGACAAAAATGAAGGGACTTCAACTCGTTGAAAAACGGCAATCAGCATCCGATAAGGTTAAGGGTTTCGTAAATATACACAAATCTCGTAGCTAATCGACACATCGGAGTCTCTGGCGCCAAAATTCGAAATCTCAGCACAAATGAAATTCGCGTTAAGCTGAAATAAACCTCCAGGGAAAAACATCCTTTTTCACATAGTTGTTCGAAATCAGGGTCAAATTAAGAGTAACTTTTAAATTTTTAAATTTCTTCAGTGGCATCTAATTCAATGCAATCACCGGCGATAAATACCTGAACATTCAATTCTTCGTTGCAATTTCACGAGTACTCCAAAAAAATCGATTGACCCCATTAAAATTCGTCAATTTACAACTATTCCAGCTTATCTTCGACGAGGCAGTCTGGATATCGAAAAAGCCATTTCTTTGAGCATGCGGTCAATGGCTCCAACAATCGATCAAATGCGGCTTATGATCATGCCAACGCGACGGAACATCTTCGAACCCAATCCGTTGAAGAGCACGTTGTTCGAGCTGTTCGAGAGCTCCGAGAGACGTCAAATCGAAAATCCGGTGGAAATGTGAAGGGCACAAATTAATGAAAAACCAACGAAAATGGTGAAACTAGCCAACTCGAGATGCTCACCGAGAATAAAGCATACGATGGACGGAGCATAATAGAAAAGTTGAATTCATTCAATCATATGTCACAAAAAAGGAAATTTCCTTAATTTTTCGGTTTTTTTTTTCGGAAAAATCTAATTCTATGCAAAAAATTTAATTGAAAATCCGGAGAAAATCGTATACTTTTTGTCGAACCATTTTGTGGGCGGAGCCTAACTAGTAACACTTTTCAATTTATGGCCCATCTCGAACAGAAACGTGAGAAAAAATTCTTCTTTTTCGCGAAAGTCTAAAAGAAAAAAAAATCGGAAATTTTTGAATTTTTCGGTTTTTTCTGAATTTTCCAATTTTCATTCAAAGAAGGTCGAAAACTTTTTCGGCGATTTTCCGGTTTCCTTTTTGAAAAAAAATATAGATTTAAAAATGTGTAGTTTGTAGTTTGTAGTTTTTGCAGTTAATGTCTTCCATTTTGGATAGGCGGCAACAAACCTGCTCGACGTGGGAGCACGAGTGTCTCAATCAATGGACATCTGTCGCTGCCGATTCAATCGATATCGATTTAATACGAATCTGCAAACAACACCTGACGTGTCGGGAGGTCCAATAATGGCGGACATAAAACTACGACAATCACGTGTCCCGTTGATGGAGTGACCTGGCGATTGCCGAATGGTCACTCGCATTAAGATTACAATTGAATATCGTCGAATGATATGGAAGAGGATATTATTTTGGAAGATGCGCAACAAACATTTACAGAATACCACTGGAGAACTTTCTGTAGAGACGAGGTTATAATGGTACATGCGGTCGGGTTGTAGCGAAATAATCATTTTTAAAAATTTGAGAAAAAAATTGTGAATTTTCCGCGTAAAACGTGATTCAATCGCGAATTATTGTATAGATTTTTCCGACAATTCGGAAAAATGCCGGAATTGAAAATTTCCGGCAAATCAGCAATCCCATGGCCGTAATTCCAAATTTCCGGTAAAACGGCACATAGCCAATAATTGACAATTTCGGCAAGTCGGCAAATTGCCGGAATTCAAAATCTCCGGCAAATGGCCAAATTGTCGAAATTCAAAATTTCTCGAAAATCGTGGCTGCTAATTGCCGGAAGTGAAAGTTTTATTGATAGAGATAAATTAGAACTATCACTAGAATATGTAAAACAACTAGGAGTTATCATGTAAACTTGTCATTTGAATTTAACACTAGCAAATAGATTGGGCTTCAGATTTTGAAAAAATTAATATAACAAATCAGGAATTTTTTGAATTTATCCACATTAATCTCGATTCGGTATCAGGAGCATAAATAGGATCTTTTAAGATATATTGACAAGAATTTCCGATCAAAGTTTCAAATATTTTTTACCAATTAATGGGATAGAATGTTACATGAAACATTACAAAAAAATTATTCATCAGGTTCTCGTACAACTCCATTCCGTCTGTATTGGCCAACTGTCGAAACTCGAAGAATATCGTGAAACGGTATCTCCCGTATGAAGCAGCAGGCGGTCACCGCATTCGTACAACAAATTCAAAATTCGTGTCCAAACAGTCTGGCGCAATTCGGGTGACGACTGGACGAAAAAAACGGTGCAACGGGTGAGAAAAGGCATCAGTATGAGAATATGAATGATTTGGAAAGTGGATAATTCGTTGAATTCGGCGGCCCGGAAACTCTATGAACTCCGGGTTTTGTGCAGTTGCAATTTTTGAAGTTTGTGTTGAAAATTCAAAACTTGCACACGAACGGATTTTAAATTCGATTTTTCGCGATGGTTGAGCATTCAATAAAATTTTGAAAAAATGACAAATTTTTGAAATAATTTCCGAGAAAGAGTGTAAAGTTTCAGTAAAAAAAATTCGAAGATTAAAATTTATTTTAAAACTTAAAACATCTGACTTTAAGCGAATTTTTTGACAAAGTATTTAATTAGTCATAAATTAATTCAAAAAAATTATCTAAGATTTTTAAAAACTGTTTTATACAGTTTCAGAAAAATTTAAGAAAAAATTTTTTTTCAGAAAAAACCGGATTTTCTGTTAATTTGAAATTATGGAAAAAAAACCCCAAAGGGTATTACGGAACTACGTCAAAATTCTGAGAATGCGTACCCCGCAATATTTCTGTGGAACTACAATTCTAAATGACTTCTGTAGTGTTGGTGTCGACCTTTACGGGCTCGATTTTAGATCGAAACGTTATTGAGCAGAAAAATTATCACATAATACGAAGAAACGAAGGAAAATGAAACTAAGTTATAAAAAAATTCGAAAATCGAGATCCCGTAAATCGACGCGCTACAGTAGTCAAAAATTAACTTGAAATTAAAGGATTACTGTTTTCGCTCCGAAATATTTTGCGAGTCAAATGTCTTGCGCAATACGCAGAGACTAAATCACAAAATTCTATGCTCCCGAAATAGACTGAGAAAATTTTTCCAAGAAAATTCCGTTTACGTCGAAAAAAAAGAAAAAAAGGCGTAAATACACCAGTTTTAATATTTACTGAAAAAAATTGGTATAATCTAAAAGTTAATCAGCTGAAATTGATATGTTTTCGGATAAAAAATTTTGGCGGGAAACTCACGTTAAAAAAAAAAATTTCAGTATGCATCAGCCGACTGGAAGACGACGACGAAGCGATCCGCGCTTCATCTCTCATTTCCCTTAATCGATGTGATCTACGAATACACGAAACGGACGTCGGAGTGATCCCCTGGCCTTGCTCAAAGAACCAAATCGAAGTTCCAGTCGAGGCTGTGGATAAGTGCCACCTCACACATGTATGCCTCCAAGTGCTTCTCCATGGAAAAAACGCAAATCACGAGACACTTATCACAGATTCTGTGACATCTCATCCTACCCGTATCACGTTTTGCACACAATTTTGATGTATGACTGACGTGTGAGAAGAACGCTTCCAGAAAGGCTTCTTGAAAACGAGATACGCACGAGCTGACCAATTCGTCTTAAGGAGATTGTGATTACTATTCGATGCTCACCAAGCTTATACTCGGTACATACGGCGGCTAAATTTTTTTAGAAATTTCGAAAAAGACGAGAAATTCGATTTCTTATCAGTTTACAAAAATCTTCGCTCCTGTTTCTGACAATTTTAGTGCCGTGGAATCCATTCAACGAAAAAAATTAGGTTCTACTGGTTATTTTTGAGCATATTCAGTAATTTAAGCCATACTCTTTTACTTCTAAACTATCCGGTGACGATACGTGAACAATGTCCAAAATTATATATTATCTAACGCTACAGCATATAATTTTTACCAACCATTTTCATTCATTTTATGGAAAAAAGCATCTAGAACATATGTAATATGTTCAATTGTTCGATTTCAACAAAATTCAAACCGACGGCATGCTCCTTGGTTTGAATCGAAAGTTCAGAACAGTTTTTCATAGGAGAGCAAGAAATTGCAATGCTTGACGTGAGAGGAAACGTACGGATACAACGTGTTGAAATAAACGGAAAAAAACCGATGTACCGATGGCCACATGATTTGAAGATTTTCAAGTAAATTGTCAATTGTCGATTCACACCATTTCGCAAAAAAGGTTTGTTTTTATTTTATTAATAATTATTAATAATGAATACGTATTTGATCATACAAAAATAAAATGTCTTTTCCAGATTGGTTGACCGGGTGACTACTCGACGACTGACCTAATCACATGGAAACGATGAGGTAGAAAGATATATTCACAATTGCCGACGGAATTTCCACTCCAAAAATCAGGGCAATTGAGGGTAGCGATGGAAAATGGTATAAAACTGGAAGAAGGACGACGTACGACAGGATGTGCTTGTTGAGGATAGCAAATGTTTGATGTTACGAATAATATGTTGCCGAGAAGGCGATGCTTCGGACATATAATGTTCTTCCGTTAGACACTGAATGTGGAGTTATAGAGTTTTGCGGTTGTTAGCTTAGGTTCATTTTTTTTTCGTTTTTGCAAAAAACCAAAATACTATTACGATAACTAGGCTGAGAATGCGTTTGTACAACATATTTGACGAGCAAAATATCTCATAGCGAAGACTACAGTAATATTTTTAAATTCCGACCGTAGCGCTTGTGTCGATTTACGGGCTCGATTTTCGAATATTGCGGGGCCGTGATATCATGAGTATGCCTATTTACTGGCGCGAAAATATAGGCACGGAGCCCCGGGGAGAGAGCGTGTGGCGAAGAGAGATAAGACGCAGGTCCCTTCGCTACGAGATATTTCCCGCCAGAAAATAGCATTCTTTTTCATGATCTCATGGTCCCGTAATAAGCGATTCCATCTATTTCACTTCAAAAATCGAGATGCCGTAAATCAACACAAGCGCCAATTACTCTCATTTAAAGAATTTCTTTTAGCTACGAGATTATTTTTCCCGTCAAATATGTTGTGCAATACGCATTCTCAGAAGAAGAAAGAGGCGGGCAGATAGCTGAGTCGGTATTGGTGGCCGTTAGTGGAAGTCACGAGTTCAAGTCCGGCCTCACCCGCTAGGTTCACCCAGCCTCTATTGGGAAGTGGAGCAATCCACCACTGAATTATCGGTCCCAGTCCCAGGACGTGGCTTACATCACCCAGAGGGATCGCCACCAGGCAGTGTACCTGAATCCCAGCTCCCCAGTGCATAGCACTTGAAGAACGTCGTCAACTTTAATCCTTAATCCTTTAAAAATGTAAAAAAATTTCATTGCCAAAATATCAAATTTAACTATGAGACGTTTTTTCTATTATTTTTCAGAAGAAGTTATGTGTGGTGTGACACGAGAAGGCGGTTTCTCCACCGGGAGTTCAATTCAAAAGAAGTTTCGGCGAGTAGATAAGTGTCAATGACGAGACTAGTACAGACAGAGTCCACCAGAGACACGACCAAGTTTTTGTGGTGTCAGCAGTATTCTCCAGTTTTTAGGTAATTTTTCTGAAAGTTGTCGAAGTTTTTTGTTTTGAAATTAACATAATTCCCAAATAATTGGCCTTTTTTCATTTCCAAAAGATAAAATTACAGCCACTTCTTCTACACCAATGCGACGGCGCAGATTTGGCGGCAAAAACTTATAAATTGTGTCACAGGCAGAGCTTGGCCACGTGGCGCGAGTATTGGTAGGTCTCGAACTATGCTAATCGAAATGAATTTTCGAAGAATTCGAACATCTCAGACTTTTTCTGAAAAATACATAAAACGTTATTTTCCAATTTTATCAAAATAAGAATATATTAGTTTCTTGCGAAATGCAGTCTCAACAAATCTTTTTTTTAAAAATCAGATTTTTAAATGCTTTTTTTAAAACTTTTATCGTTAAATTGAACGTTTATGAAACATGGCGAGAAAAACTTTTTTATTCGCTTTTACAAATAATTCTCAAAATAAAAATTCCAGTGTGCTACATCGTTGGCCTCGGCGATCGACACGCGTCGAATATTCTATTCGATCAGAAATTGTTCACATTGGTGCATATCGGGATGATTTTGGAGTATAGTAAATGAACTTACCGGTGCCAGTTCAGCCCGAAGTTCCATGATTCCGTATAACTCTATGGTCGACCCGATTCTGATTGAAGGAATCGAGAATGGACAGTTGGCTGAGGAACGTACGCAGATTATGGCGATAAAATTGAAGGAAAATGGAAAGGTACGGCGGTCTGGGGAAATTTATACGAAAAGAAAATTTTGGATCGCTGACAATTAGACTTGTAAAGCAATTTAAAAATCAATTCAAATTTCCCCCCAAAAATATTTTTTCAAATAATTTGAATTTTAGCTAAATTTTTAAACAAATCTGAAATTCCCGCCAAAAGTTTTCCAAAAAAAATGTTCCCGCCTAAAATGTTTTATAAATTCAAATTCCCGCCAATTTTTTTTACACAAAATTTGAATTTCGCGTCAAAATATTTTCCAAAAAATATTCTGGGAAAAATTCCCTGAATAGTTCAATTGACGCCCCACCAAATATCATTCAGAATAAAATTTTAGAATTTCTCGCCAAACTTCTCTTTCAATTCCGTCAATCCCCTCAAAATTGCCAGGGCTTTAATCCTCGGTGTCGCCTCTGCTCTCCGCGAAACAATGACAAATTGCCAAGCCGAAACCAGCAGGCTGCCGGCCGCCCGTCCTACAATTCTGAAATGGCCATCGGGCGGCTTGGAGAAAAGCTACGGGGCACCGATGACGGTGTGACGGCCCAATCGTCGTCAAATTCGGCGACTTTTACGAGAAGCTACGAGTGCTGAGAATTTATCGCGTTCTGCGGATGGATGCCTTTTTTTTAGAGAAATAGAGAAAATTTATTCTCGAAAATTAAATTTTTACTGTATTATTGATTTCTCGTATCAATTTTTCAGAATTTGCTTTGTTTTTTACGCGCAAAATAATCTTTCTAATTTAGAAATTTTTAAAATCTAGTTTCTGAAATTTCTGCAAAATTCCAGGAAATCAAAAAATGTAGTTTTCCATCCTAATCTTTTTTTTCGTTGATTTTCCCCAGAAATTTCAAACTTTTACTGTATTAATCCCGATTTTTAGGCTCATATCATGTAATGTTTTTTGTTCACCATTTACATGTTTTTCCTACCTCTTATATGATTCCCCTTCCCCGAGGTCTCTTTCTTCACAATGTTTAAAATTGATTCACTGTTGAATCTGTTGTCTTTTTTCTATGCGAATTTTATTAGTTTTATGAAAAAAATTTGTAATATTTTTGAGTAAATTTTGAATCTTCTTACACTACCAGCGCAGTTAACCATTTCAGAGGAGTTTCTAAAATAAATAGTGAATTTTTACAAAAAGTATTATGATATTCTGATTTCAGACGTACATGAATTGCCCGTTTTCAACAAAATAAAACAACTTTTTATTTGTGCCCAATTTTTTTTCAGCCATCTAATGACTGTCCTTTTTTTTTGGGCAAAAGTAATAAATTTTCTAAAAGCGTTTAAAACTATTATATTTTGAAAAAAAACCATTTGGGTTATCAGTTGGCCTTGGCAATTTTAAGTTCTCTAGCTACAAATTGAACCAATAGAGGTTTCAAAATTGTGAGATTTTGCAAAAATTGCCACATTTTGCCACTTAATGCTTTTTGATGGGTTAAACCTAGATTTTCTGAATTATGCATATATAAATTACCCGTTTTTAACAAACGGTATTAGGCAACTTTTTATTTGTGTCGAACTTTTTTTCAATGACTGTCCTTTTTACTGTTTTGGGCAAGAAAAATAATTTATTGGAATTTTTTTCTATGTTCGAAATTTTTGAAGTTTCTTGCAGCACTCCGAAAAACCAAACGACCAGCACTACTTGCAAAGTCCGAAAAAGTTTAGAAATTTTGAAGTTAAAAACTCCCAACTCCATAAACTCACGATATAGAAATTAAACGTTTCCAAACATGTCCGAAAAGTCCAAGAAATATCAGTACAATTTCGAAATTTTTTTCATAACACTTCTGAAAATAAAAAACCGAAACTGCAAAAATTTGAAAATGTGCTAAACTCCAAACTGTACGATTTTCCACATTTCAGAAATTCCAAAATTCGTCTGCCAAATCCCTTCGGCGCAATAATCCCCCGGGGTACCCCCCCCGCCCTAGAACCTTTTGCCTCTATTGTCTCTGGCGCAGGAACTTGAAATTAAACAATGAATCGATATTTTAAACTGGTAATCGTAACCATCTGCTCCGGATGTATAATCGCCTACACGAATCTATTCAATCGATCGTTTTTCAACGGGTACTGTAGTATTAATGCTACGTGGCAACAGTCACAAGGCGAAAACGACAGTCAGTGGCAAACTCGTTGGATTTGTGTCGTGCTTAGTCAGGAGGGTGTGAAGCAGTCTATTCCGCCGTGGATTGGCGAGGTTCCCAAAACAGTTGTATCGGGTGAGAAAGATTGATTTTTAACACCCGTCTCGCCAATTTTTTTCTCAGAAATTGGAATCCCCGTCACAAAACTTTTACAGAGTGAATTTTCGAAGAAATTGGAATGACACCCAAAAATTTTCTGAAATCTAGATTCTCGGCAAAAGTTTTCAGAAAGTTTGAATTCTTGTCAACAATTTTCTCAGAAATTTGAATTCCCGCCAAAATTTAAATGCCAGAAATTCGAGTTACCACCCTTCTCTTCAAGTCTAACAGTATTCAACAATATACAATTAAATAGCTTTTCAAATTCCTAAAAAGTTTGCTGGAGTGATCAATTTTTTAGTTCAAAACTCGCTAAACCACTTGCCCATGTAGACTACATAATCAATTCTGAATAGAACGCTATTTTATCCTATTTTCAGACATCAAAACCGAATAGCCTAATCGCGTGGGTCATTGAAAAATCATTTTCGATCTTTCTGCTATTATGTGGTTTTGACACGATCCAGGCCGTTGATATTGCGCCAACGAACACTGGCTGATATTTTTGGAGACAGGTTTGCGGCAAACGAACTCCGCTGTCGACTCTCGAATTATCAATTTGTGCATAGCTTTGTAAGGATAAAAACCAATTTACCGAGTTGAAGAAGATCGGAAGCTGGCAGTAAATGGCTCGATTTTCACTGTGGTTCGGAATCCGATCGATGGGTTTTGGCGTAACTCAGGCTTCACGGATAAATGTTTAAGAGAAAATGTCTGGAAGTTCAAAAATCGCGCCGGATGTAAGACTGTGCGTTTAATTTGCAATAAAATCTTTTAAACAATTTTTTTGGAATCTTTTATTTTCGGGAGTTTCGAAAGTATATTGGAGTTTTTTAGGGACCAAAACAATTTCAATTGAAAAAGGTTTTTTGAAAGGGGGTAACATTTTTCTAGGCCACTAGGTGCCCTTTGTAAGGTGGCCTAGAAAATAATGTAAAAATCTAGGCCATAAGGGTTGCATATTGCCTGATGGCCTATGAATAAGCTAGGTGCGCCATAACTTTTATCAGGGTTTAGGAACGTTAAAACTTCGGGCAGCAAGATTCGCATAATGACCTAAAACTTTCAATGGAGAACTCGGCTATAAAAATCTTCATGATGGTTTCAAAAAGCGGAACACTCGGGGACCATAATCTTCTAGAATTTTTAGTAAAACTAGGCCATTAAGGTTTCTTCCGTGGTCTAGAAATCGATTCCGGGCCAATACTAGGCTGCCAGGGTTTCTAGGCCACATAAGAAAGGCCTAGGTACAAAAATTATCTCAGAACGGTCTAGAAAAGTGGATAACTAGGCCACCAATTTTCACTTCGTCAGGAGTTTCAAAAATATATGATTTCATGATTTACTTTTCGTAGTTAAGAGTCTTTTTTTTCAAAAATTCTAAGCAAACTTTGACACTAAAATGCTTGAATTTTTGAGAACTTTGAAAAGTGTTTAAAAATAATTTTTTGAAAATTTCTCAATTTTTTTTCTTCGAAAAGCTCAAAAAAACGATAAATTTCCACATTTTGGCCAGAATTTAACATTTCGTCGATAAAATGTACGATCGGAGGCATAGATTCGCGCGGAATCCGTACAAAGGAATCGTTTTCGACGACAGTCACTTTTTCCCACAATCTTGGTATCGGTAAACGCGCTCGGCATTATAGATAAAGTTGGAGCGCATTTGCATTTTGAATTTTGATGTCTGATATTTCTCGTTATCCGTCAGGCGATGCGAGTTCTCGTACTCTCATCTTGGAGTCAAATACCAAATTTTCCAATTAGCCGGTGCAAATTTCACAAATCGTGTGAACTTCTTGGACTGCTGTCCGAGCGGGGAGTTGATGAAATGGAATTAACTTTATTGTGAGTCTTAATCAAGTTTGGGTCTCATAATACCGCGAAAACCGTAATTGATTGGGACAATGGGACCCAAGAGAGCACCCCAATGGAGCGGAATTGCAACTCCTATTTTTCCAGTCGGAAGTCTCTGCCATCACCGGACCCCACACAGCACAAAGGATTCCGTGGAACGGGCGGCCGTCCAGGAAACTGCTGAGTAGTCCCCAGTATTTGTTGCGAAAATTCAAATGTATAATTTTGACTTTTTGCAAGATATTCGGGTATAAGCTTCCTGATATTGCAGTTGGAAATTAGTAAAAGCGTTAGTATTTAAATGTTGTTAAATAGTAATAATCGATAAACTTCTTGAATTTTGATAAACTACGGCCACGTCAATTTTTAGATATTTAACTGTCCGGGCAAAAAAAACCTAAAATTCCCGCGTTACAAATTGAAAACAAAAATTTCACAAAACGAATAAAAACGTCTAAATGTTTATAGCTTAGGCTGAGGTGAGATTTAGGCTTGGGCAGGTTAGTTTTTAATTTTCAAGGTTTGTCATTACGTACTTTATTTCCGAAATACACAACAGAAGTCTCACAACGAGTCAGGGGTCAGTGCGTGTTGGTGGGTGGGGTGGGAGATTCTGGTGGGGACCACCACTCACAAACAAAGATCACAACAGGGAAAATGTACACGTGGCAATATGGTGAAGCTATATGTATATATAATGAATAATGATATGAAAATTTGCATAATAGCAGGAACAGTACCTGATTGTTCCCTGGGGCGAGTAGAAGATATGTGGGTTATCTATCGATTACCATTACACATGAATTACGCTGTTACGGTTAGAATTTTGTGAAAAAAGATGAGTAAAACGCTGGGACGGGGCTATAAATCATATCTATAATTGTCGAAGATGCTCCACGAGCCAGGAACGAGGGGAACATTGCGTCAAGGGCGGTCATTCCATTGTAGTGATGATGGTGCAGCTCGTGCATTGATTGCTGTAGCAGTAGGGACTCCCCTCATCACCGAATTGATAATCTTCTTTCCAGATGAGAAACGCTCAAGACGGGAGGCGTGTTGGAGCACACGCTGCTTCATTTAATTCTCGTACCATCCAGAGTAATAAGAGAAGCAGAATAGCTGGTTGAACTTGACGTCCTCTGGAAAAAAACAATATTTTCTCTAGTTGCCCACTTAACACTTGGACAGAATTAGAAATATTTAAATCAGGGCGGGCGGCAATTTAAGGTTTTTACACTGGGGCAAATTCAGCAATTTGCCTATTGCCGGAAGTTTTTAAAACAGGCTCTTTAAAAGACGGATACACTTAAAACTGTGCCTTTTTGAAATTTTCTCCCGATTTTTTTACATTTTTTCATAGATTGTACTGACTTTTCACAATAAATGTAGGCATTTATAGGATGCATACAATTTTGCCGATAAAAATTGAAACTGTGAAATTTTCAGAAAAAATGTGCCCACAATTTGCCGAAAATTTTAGTTCCGACAATTTGCCGTTTGCCGGTAAAGTTGAAACCGGTTCCCAGGCCACGTACGGATCAGTTTTTGAAGAAAAAAATACGGCAAATTTACAGAATTAGTACCATGTGGATTTCTTAAGAACTATTGCCAAAGTACGTAGAATGCAGAAAGTTTCTTGCCTTAGTGAAATTTTGGAATTTTTCGGGATTTTCGGAAAAAAAAATTTTTCCATGAAGACGAATTTCTTTTTCAAAATTTTTTCACGAGTGTAACTCTAATAATACGCCTCAGACGCGAAACGTTTTCCGATCAAAACACGGCCGGGGTCTCGAATCGACATGCAGTATTTTTCTCGCTTTGTCATAGTTTACTTCTCGACAAAAATGGATTTTTTTGAATTACAAAATCCTTAAGTTTATCTACCCAGAGGGAGAAAAAGAAGACCTCCCTATAAAAATTTGAAGAGTACTCATTAAAGGCGCCCTTTTTTCGAACTTAACCAAAAATTGTCGTGTCGAGGCCTGGTACCGTATTGTGGTGCGAAAATCATCTAATTGCGGCATTCGATTTTTGCGTTTTTTGTTATTTTAAAAAAATGTTCAATTTTTCAAAAATAGCTTTTAGATAAAAATAATAGGTTATTCCTTCTTTTATTTTACGGTCTTCTAAATAATTTTAACATTTGGCACTTACGTTTCATCACAGAACAGAAACTAAAGACTCTGTGCCAATCAAAGGGGCGGTGCAAATCGAAATCATTTGGTGAACAACATAGTTGCCATACTGGTGGAACAGAAGATTATCCCAAACGCATCACGATACGACTCGACATCAATCTTCACAAATCCACACTATGAAAATCTCCTCCATCATCTCGTGAAGCAACGGTCGGGCGGTGCAAACAAGTACGCTCCCTCGATGACGTGCGACGCATACTTGGTGACAATGATAGCTAGTTACGGAGCAGGCATATATCGATGATAGTGTCTCTGTACATTTCCATGATACGTTCACCGACGATTTGATGATCCATATTGGAAGACGTAGTTGGCGAACTCGTTGGAAGACAGCCGGTAGCAATTACGGACGATACACGTCATCAGAGAATGCAACAATTGAAGATGGAATTTGAAACACGGGAGCTTGGGATTCTCGGGGGGTCTCTCGATGACCTGTTGCACGAGAAGACATCCATACTTGTCATCGGGACTGGCACACGGCCATCGGTGAATCTCCTGAGGAGAGGAAATGCGCGAAAAAGGTCCACATGTCGACTGGACGGTTTTCGAAGTTTGACGACACGTTGAATCACGTGGATCGAGATTTGATCATCATCCACAAGAGATCAGCACATTGCCGCCAGGCGAATGTGCTTAGCTCTTGGATGAGCTGGAAGACGTTGGCATGGTCGAATTTCTGTTACAAATTATTGATTTGTTACACCTCGAAAGGCCTAAAGACACCAAACATAGCCCTAAAAATTTCGAAGCAATGGATTAATTTTAGCTAAAACGTAATTTTTTGCCAACCTTTCTGTGTCTTTTTTAAACCAAAATCGAACAATTTCGTTGTACGATATTTTGAACACATTTCAATTTTTTCGGGGATAATCGTATATTTCTTTTCCTCTAGGAGCCTTTTATGTGTATGTTTTTTTCATCGACAAAAAATTTTCGTTAATGTGTGGACCTTTAGGTAGTACTGTAACTTCATTAAACTTTCATTGCTGCGGAATTTTTTAAAATTGATTTTCAATGTTTTTCTACAGTTGTCGTCCAATTTCATCAAAGAAAAAAACAGAAGGAAAAAACATCGATGTGAATTTAAAAAAATTGCGGATCAGTGAAAAGTTCGGAGTTTAACAGTACTCTTTGAAGGCGCCTGTAACACCTTTTTTGTTTTAAATTTGTCGTGATGAGACTCGGGACAGTTTTTCGTTGCGAAAATCGCTGCTTCGGCTCATATCGAAGAAAAATCAATTTCCGACCGCTGCGACACCTTAGCAAAGGAAATTGTGATTTTAGCCAAAAATCAATTCAGTTATATATCGGAATTCCCTGGCGAGACGTATTTCTCCCACAGCAACTGCACAACGACATGCGAATTTATCCTTGCACATGGCAAAGGCAAAAGCCCACCGTCGATCATTTGACAATCCCCGCTGCTCGGCCGGTGTTGCGAGCTCGACGAGCTCAGCTCTGAACCATGAAACGATATTGCACTTCGACTGTGGCAGAGCCCCACGAAGAGCGTCGTGGATTCGCTGAGCTTCTCGAAGCCGGCTGTACGAATCTGATCGTGGGAATCCAGTGGGTAGTTGGCTCCAAGAACTTCACGCCCGATGGATCGATTGCGAAATCGATGATCTGCCCGTTGCAGCACATCTTCGAGCGAAAAGAAAATCGGAGCAACTGGTGGTGGGGTCTCATCGTCGGAGGAACCCGATCCACTGGTAAAGATGTTGCTGTCGAATCGGAGAGTGTTGCTTCCGTGGCGGTAGGGAAGAAACTTGACCGACGGCTTCGGATAAATTCGAATTTTAAATTTTTATTATTTTCTATTTAAATTCGAATTCCGTTTTATGCGTTCGAATATTCCGCGTTGTTCTTGTGAGTTTTGTTCGACAAAGCGAGAAATCCGGGTCGAAATCGAACGACGCGCCGAGCATGTTGGGCTGTGCTTCTACGAGTCGGGGTCATTTAGACGGAAATGAATGAATACAGGTTAGTAGACGCTGAAAAAATTTGGGAATTAGGATTTTCAACGGAAAACAGAGTGAAAATGAGAGGAAAAAATGTAATGATTTTTTTTCAACGAAAATCGCGAAATTACATCAAAATTCAACATTGAGGCCATTTTTCGCGGTGGCCCAGGTTACGGTGATTTTTAAGCATGGTTGTTTTGAGTAAGGTCTTGACCCGTTTAAAATTATTGAACATTTCATCATTTTATTTTTAGTCATTTTTAGAGAACAAAATGATTAAAATTCGATTTCTTAAAATACATTTTCACAAAAATTGCAAGAAATCGCTGGCCAAAATTCGAAAATGAAGAGTTAGGCGGTGCTCATGGATTACGGATTTAAAGGCACATGGCTTTTTTTTTCACCACGAAAGGAGGATAGTTTGCTTCCCATTTTGGGGCCGATTTCTTTTTTTAATTTGGCTTTCGCTCGATTTCCACACATTTTCACTCATTTGCACTCAATTTTTTTGCAGAAAAATGTCAATGGATATGTTATGAAGTCAGATGAGCCGGCGTTCATCTCTGCGCCGGTGCAATATGACTTTAAGTAAGCTCAAATGTTTGTTATTCTGGCCTAAAATTATTTTTATGATTTTCAGAACGTTCGCATTTTTCGCCAAAGATCCGAAGAGGAATGCAAACTTATCTTCGGGCTCGAACGCTCGAGAAAGTTTCCAGCAGGCCACGGGGCGCTCGGAGAAGATCACGGAAGACATTTCCGCCAAATTGAGTAGGTTTTTCGATTTTTTTACCCTTAAACTACTATTATTTTCCAGCGTCTCCCACATTTCGTCGACGGCCTTCAAGAGAGATGGTCGGTGGCATCGAGAGAAATCGGCTCGGCTCGCAAGCGATTCTGCTCGACGAGGACTCCAGGCGCCGCAGTCCCAGCATTCTTCAAATCGATCACGCTCCGCTCTCCGCTATGATTCGAGAGAGTTGGCAAGGAGATCGCCTCATCTGATGCCTCCGACTTTTATCGTAAATTATGGGATGATGAGCTCGAAGAGGTGAAGGAAGAAGTGGTTGCCGTTGGAGAAGCCGTCTTGCCCACGCCAAAAGTCGAACTGAACTATGGACCCAGCATCCGGAAAAGGACCTGATCGTCAGCATTTCCGTGTATCTCGGCTACACCCGTACCCTTCAAATACCACGTGATTCGCGGACGTTTGATGAAGATCACGGATCCCGGCTCGAGCTCACATCAGAGACACGCTTCGCTGAAATACGCGTTCCCCCATTCTCGTTTTCCGACGATTATAGCGAGAAAAAGCCGTCGAAGAATTCAAGGATATGGCGAAAAATCAATGGCAGTCGACGATGTTCTTCATTCAGGACAGGTTTCATAATATAACTGGAAATAATTTAATATTTTTCGAACAAATTTGATATTAACCCATCTTATTTTGATAAAACTCCGCCGCTGCTCTCTGAAGCAATGAACTGCAATCCGACATCAGCGAAGGGATCAGCCGAACTGAGACGGAACCACTGCCATTGAGCTTCTAGCGAAGGAGAATTAATTTATTTGAATTTATTGTACGCAATCGTTCCCATATCTGTGAGCTAGCAAGCTAGCTAATCGTGATTAATTGTTGGGTATTCCTTCTCGTTCTTCAGCTTCTCCACAAGCATCTTGTCTGCTCATAATCACACAAATGATGTCATCAGCATCGCTCTGATCTTGAAAATCCTGAAATTATAACATTCTAGAGGGTTTCTGTTGAGTATAGTTACCTTACAACCAACACCAAATATGTTCTTCATTATGGCATCCGGCAGCTTTCCATGAATCGCAGAAGAAGTGCTCGGCATCAGATCGGATGCTCTACTTGGGAAATATCGACCGATGCGGCTAGACACGAACCATGTTGAGTGGCCGAGAGAGGGATCATCTCAAAGATCTAAATGTAAACTAAACAAGAGTTTAGAAAATTTAAAACAACCTCCCTGATAACGTAGTTAGCTTCTCGCGGAGTGAGCTTCTGCTTCAAAATGAAACAGAATGAAACAAGAATCAACTGTGTATTGTACAAAGTGAAGTATTTCAGACATTTTCGCTAATTTTGGCAGTAAAGACCTATAATTTTGGTAAAAATCGCTTGTATTCTGAAAAAAGAACTCAATATTTAATTTTTTATTTTTAACTGATTTTAAAGAGAAACAAACGAAATATATGAAATCGAAGAAATCCCTGAGAAAAAAAAGGTGCTCCTCCGCAATATTTGTGATTGTTAAAGGGACAACGACTGTTCATCGAATGGGTCCCTCCACGATTGTCCATGTCGAGCGCTTTTAATCGCGATATTTTACTACTGTAAAAAAGTGTACTAGGAAAAACCTGTGTAATGTCGAAAACGTCACAAATGTATTTAAATACATGTTTTTATTGCTTGAATAAGCCGGCAAAGTATGTATTTAAATACACTTTAATTTTCCGACATTATTTGAATAACCCCAAACCCCGAAATTTATTTTTTGTGAAAGTGATAACCAGAAAAATACATGTTAAAACAATTTTGTGAACAAAAAACTAAAAAATATTTTTTTTGCAGAGATGAATCCCACGTGAACGGTCGAATTTCCACGCAGCCTCGTCGAACGGACTTTCAGAAGAATCGCATGTGACACGTAGGAGGCGCCATGTCGGCTCAGTGAGTACAAAAAAATCCATGGGGATTTTATAGAAAGTCGGAATTGATTCAATAAAATCGATTTTTATAATAAAAAAAAGGATTGATTATTGGTTTTTGAAAAATTTAAAAATTACAAAAAATCTATAAAATCGATTTTTTAAAAATTGAAATTCAATAGATTTCTAACTTTAGAAAAATCGAAAAATAATGTTTTAAAAATCACCCAGTCAGAATCGATCAAAAATTCAATTGTCATCGATTTTATTTATTTTCAAAAAAACTTAATTTTTATGAACATCGATCATATCGGATTCCAAAAAAGAATTGGGAAAAAAGTAAATTTTCAAGAATCGAAAAATTTTAATTTTGTACAAATAGTTATTAATAACTCATTTTTTAGGTTTTTTTTCAAAAATTTGAACTAAAAACACTTATTTCTCGAGCTTTTTTCACAAATTGACCCTATTTAAATTAAAAATTCACAAGCCAAAAACCTTCTATTTTAACCAAAAAAAAAACGAAATTCCTCTCCCAAAAATCATCAATTAAATCCTTTTCAGCTGGATGATCGTAGACCACGACAATCGGCTTCCCAACTCGCCAGGCTATCTGTGCTCTTCGTGCTACAAGGTTAATTTCCTCTGTTTCGACGTGAACGGCAACAAAGTGTGCCATAAGGCCGTACCGTATTGTGATCGAAGGGAAATTGGCCACGGACGCCAAGTCTTTATCCAGCTCGATCTTTAGAGAGCGAAATTTAAAGTATCATTTTTTCTTGTTTTTTTTTATGTTTTTCGATTTGATTGTTTAATTACCAATTTTTGGCCTGTAACTGTGTATTGGTTGTGCAAATTTCGTTTTTTGAAGGTTTTAAATTTCTGTTTGGGGCAAAAAAATTTATCCAATAAATAAACGGAATATATCGATGATATGGCACGTAGGGGGAAACGGACGGGCAAGACTATTTACAGCAAGGGCGCGCACCAGAGGTTTCTCGACCCCCGAGGCGGGTGGCGGAGCCTCAAATCTGTCGGAAAAATGTGAAATGAGAGAAGAAGTAACCTCTAGAAAAGGAGATGAGAAATCGGAAGTTCTGGGAAAAAAAAATCAACTTTTGAACAATTCACATTGACGATAATATTGATTTTTTTAAAATTCTCTAAGATCGAGAAATCTGGTTTGGAAAAATCAATAAAATGAATCTTAAATATCTTTTTAATAAACTATTTTCAAAAATCAATAATATCGATTTTTGAACAATTTGAAAAATCGATAATGTTTATTTGTAAATTTAAATTTTATTGATTTTTTGATTACAAAATCGATTGTTGATTATTGATTTAAAAATCACCAGAATCGATAAATCTGTTTCGGAAAAACCATTAAAATTGATTTTTACAAAAATCAGCCAATAAAATAGATTTTTTATAATCAAAAAAATCTATGTGCTTTTTAAAACCGAAAAAATCGATATTTCAAAAATTGAAAAAAATCGATCAATAACTAAACAGTCAATACATAGGTGAGCACGTCTCATCTATTTGTGTTTTTGCGATTGGTCTCGACAGTTTTGAGACCGCTAGGCGTTGTTCCGCATTCTGGAATTTTTTTGTGTTGGGAATTTGGCACGCCCACCAAATGGACGGTGGCGGAAATTCAATTATTTTAAATACCTTTCTGGATAAAGTGCAAAAATGGATTTTTCCACTTTGTCCCTTCGAGTGATTCGGAAATTAAATAAAACATTCAAATTATTTAGGGGCAACGAAAAAACTCTCAATGCACCCACTGTTATTCGGAGTGTCGTCGCGGTGTGTTGCTATGGATCGTGTCCATGCCCAGCTTCATCGTCGACTGACGTAGCCGTTTTCTGGTGATCTGAGCGAGATTTATTTAATTGATTTTTAGGAAAGGCGCATGGCCTAAAAAACACAACACTTCGGCCAGGGACTTTGGCGGCCGAGCTAGGCCATGCTGCGGCATTTAAAAGCACATACCCTACCATGATAAACTACTGAAAATCGCCAATCCGAAAATGATGACCAATGCGAAACTGATAACTGCTTACAATCATCGATGAAGGAATAAGATGAAGTTTGCGTGGAAATGGAATCGATGTACGCTTGTGAGGTCATTCCTGGAAGTTATTGATTTATTTTTCGAAAAAAATAATTCCTTAACGCAATAGTCACACTCAGAGTCAGCGAATTTTGTTATCCGAAATCATAGAGGTATTGCGTGAAAATGCGGCTTCCAACCTGAATGTTAAAAAAAAAATCTATAATATCGATTTTTTGAAAGTTTTTGGCGAAAAATTGATAAAGTTCGATTGATTGTTTGCCCATAGAAACAGATAAAACTCTATATAACTTAATATCGATCTTTCGTTTTTTTGCGCACCTTTAAAGAGTACTGTAACTTCAAACTTTCATTGCTGCGAAATTTTTTTATCGGTTTTTACAATTTTTTGTACAGTTTCCGTCCAATTTTACAGAATTGAACAACAAGAAAAGTGAAAAATCGTAAAAAATGTCCGCAGCAATGAAAGTTTGGAGTTACTGTACTCTAGGCTTTAATGGCGCACACCTTTTTTGCTTCAACAAAAATTTGTCGTGGTAAGACTGGGGACTTTTCGGCGTAGAAGTCGCACAATTTCGGTATGGAAGAAAAATCATTTTCCAACAGCAGCGATACATAAAAATTAGCAAAAAATTGTGATTTTAGCCTAAATTTAGTTATTTTTCGGAATTCCCGTGGCCAGACTCATTTCTCGCACCTGTGATAGAGCCAACTGCACACCTCGACATGCAAGCATTTTATCCTTGCAGATGGCCAAAAGCCCTCCGTCGATCATGACGAAGCAATGCCCGCTGCTCGGCTGTTGCCAGCTCGACGAGCTTCTGAATTAAGATTTGCGATTTCGATTGTGGCACCCCACGAAGAACGTCGTGGAGTCGGGGCGCGAAGACGGCTTTACGAATCTGATCTTCGGAATCAAGTGGGTAGTTGGCCTCCAAGTACTTTACGCCCGATGGACCGATTGCGAAATCGAGCTGCCCGATGAGCAGCACATTTGAAGCGAGATGGTGATCGGAGCCACTGGTGGTGCAGTCTCATCGTCGGAAGATCCAGATCCGAAGGCTGTCAGAGTCGGAGGATAGTGTTGCTCCCGTGCGGCGGTAGGTAAGAAGCTTGACGGGCGGCTTTGGTTTCTGGAAATTCTATATTTGAATTTGAAAAGCAAGAAAATTCAATATTTTACCCTCGCGTCTTGTGGGTTCTGTTTGACATAAGCGACAAATCCGGGTCGAGCTTAATTACCGCATGAAACGCCGAACATGCGCGCCAACAGAAATGAATGAATACAGGTTAGTAGACGCTGAAAAAGTGGGCAATTAATTCAGGATTTTTTAACGGAAAAATAAGTGAAAGGAGAGGCAAACACATCTGCAAATTAAAATCTCCCGAAATTACCGCGCTTTAAAGGGACTCCACCGATCGGACAGACGAGGGAAGTGGAGAGACGCAAATCGAAGAGACGCCTTTCAGATCATTTTTTCGTGATAAGTTTGCATGAATTGGCAAGGAGAGCTTACACGTTAGGCGAATCATTGATAAAAACATCCAATTGTTGTTTGTAGTGTACTGAAATTCCGGAACAATAGCTCTCGTAGACCCGAAAGTCGCTCGTGGCAGGAAAGTGGAATTTGGATAATTTTGTTCTTTTTTTTAAATATGACGTTTTTGAAGGCTTGAATTTGTCTCATAATTCATCAAATTCATAAACGGAATTATCCAAATTCCACTTCACGGAGTGACTTTTGTGTCGAGTCACGAGAGCTATTGTGCTGGAATTTCAGTACATATGTAGCAACAGAAAATGTTGTTTTTACCAACGATTCCCATCATGTGTAAGCTCTGCTTCGGTTGCCACTTCATGCAAACTTATCACGAAAAATGTCTGAAAAGGCCTCTCCGATTCGCGCGCGTGTCAGGCCTCCACTTCCCTCGTCTCTCCGATCGGTGGAGTCTCTTTTGAGATTCGACCCAAATAAAAAGTGCAGGGCGCCCGGGTTACGGGAACTTTAAAAGCGCATCACGGTTTTGAGTGCAGGTCTCGACGCAAGATTAGCCGGCTACTTTTTGAAGATTTGTCGTTTATTTTGGCATTTTTGAAGGAAACATAAGTGAAAAACAATTTTAATCTTAATTGAGAGAAACTTGAAACTAACATTGTTACACATAAAAAATTGGCCAAGAAATTGCGCCACGTTTTCAAATAGAAGTATCGCGGCGGTCAAGCCGTTGATTACAGCCGTTATACACTCATATAACTATGCGATAATGTAACTCGATGATTTGTTGATGTGATCTTTAAAAAGGTTGAAACTGCCCCTTATGTGCCGGAGGCGCTGTGAGCGGCTGGTTACTTGTATATAAAAAATGTCGGGAAAAACGCACTTCCGTTCCATTTGTTTCTTTGTTGACGTCACTGAGAATTATGGGGGTGCGGGCCCGTCTTCGTGGTAAGACCCATCTTGGCGAGACATAGCGTGGTGATATCCTTCGTGGCGAGACCCATCGTGGTGAGACCCATCGTGGCGATGACCCATCGTGGTGAGACCCATCGTGGTAAGACCTACATCGTGCCGAGACCTTTCGAAAATTTGGTGGGAATTCAAATTTTCTTAGAAACATTTTTGGTGGGAAGTCAAAACGCCTTTTCAAAGAAAAATGGCTGGCGGGAATTCAATTTTTCAATAAATCATTTCGGCGGGAATTCAAAATTTCTAAGCATAATTTTGACAGGAAATTCAAATTAGTTGAGAAACTCGAGTAAATGGAGTTCTAGAACCTTCCTGGAGATTGGGGAAAATTTTGGTATGTTCTAGAACCATCGGCGAACTTAATTCTGGAAAGTTCTAAAACCTTCTAGAAAATTCGTGACAAATTCTGGATTGTTCTTGAAATTTTTAGAAGAATTCGAGAAAACGCTGGAACGTTCTATAGAGCCTTCTAGAAAATTCGGGAAAATTCTGGAATGTTAAAATCTTCAATGTTTGCGCAAACGCTCTCGGAAAGAACCGGAATGGATTCTGTTGTATGTTTGAAGAACGTCTAGAAACGTTCAAGAACTAATTTAGAAGTAGTTCCGAAACCTGGTATTCTTAAGTTGTAACTCTTGGTGACAACTTAGTTATATAATATTCATGTTGCGTTAAAAGCTTCTGGAGCAAACTGAGAACAACGTTCCAAGGCTTAGTAATTTTAGAATTTCATGTTAAGTTCGATTACCAGTCGGAGCACGCGCATTGTTCGGAACGGCTGGTATACAAACAATAGTCAGTCAATCCCATGGATCAAATCTTGAATTTTATGGGTCTAAAACTGAACTGTTCAACTTTGATATGCAAAATTTTATAAAATTATTATTGAAAGACATGAAACAAACTTGAATTACGCGAAGTAATGCTGTGAACTGAACTTACTATTAGATTCCTTTTTAGCGAGCACACTTGAAAACGAATGAAATAAGGTATGTGAGAATACCGTATCAATCAGATACGTCTGACACTTCCCCAGAAAAAACTATCAGAATATGAGTACATGTTAATGCTAGTGTGAATCTTTCCGCGACGACCATCATGGCTCAGCAGGTAAGACTTCGGCGACGCCTCGAGACGACGAGGTAGTTGACGACTTTTCTCAGTTTTTTAGGCAGCGCCCAACTCGTTGTCCGAGGTCTACAGTAGCTACATGTTTCGGACGGACAGAGTATTTGCTTTATTAGTAGTAACAGAAATACACATAAAATCAATTAATAAGACATGAAATGCAATACTGAACCAAATCCAGTTTTCACCCACTATGTCTCTCATTGAAGAACGTTTTAAATAGCTTTTGGTATAGAATATATTAAAATTCATTCTTCGATTTTCTGTGGAATTTCCTATTTGAATTTTTCCATTCCAGACAGTCACTTCTCCAAATCCGTGCATCCTTGAAATTTTCTTTGGGGATATTTTAAATATCATCGAGATACCAACAGTCTACAGACTGGTTTTTCACTTACAAGACGTGCTCTTGACTTGAATGTCTGGGATACCCTCTATGTTTTTCTCCTTTGTCATGCTGATAGTATAAGTTGAATGTGACACTTCGATTTCTTCTGGCTGTTTTGTTCAGTCGATCGGATTAGTTGGAAGCCTGTGACTCGGTCCATATTGTTTCTACCAGAGTAATGAGCGTGGACTAGGAAGTAGAACGGTCATACTCTTGGCTGGGAAGTTTCGTTGAACATATGGAGACAATCACATTGTCCATTGGTGAATAATAGTCGTTTGCCAGTTGTTCGTTCATTTCGAGTAACATATCCTCAGAGTATTGTAAATCAATCTCCACTTTTCCCAGAAGAACCCTCGAAACGGGTTGGGTGTTGAATGGTACATTGAAAACGGCATTTGAAACACTAGTCTATAGACGGTTCCAAAATTAGGAATCCAGATTTGAACTAAACATAGTATTAACATTACCACTGTTTCGATCCGGAACTCCATTCTGAATTCTTTAACCTACCACTTTGAAATAAGCATCACTGGTATAAATCTCGGATTGAAAGGAACTCTATTCCCTGTATTAAAACGGTCAATCTGTGGCATGTTACCAATTAATTGGGGCAATAATTTGCTCGAGCACCAACTACGTACCTCCCTAGTTGCTTTTCGTATATGGTCCGATAAAACAACCTGTAAAATGTTGTTAATCTTTATAATGTTCCTGAACATATCATGTCAAGAGTGTCTTCTGGAGTTTTTCATCAACAAAGACAAAATTTGATTTTTTAATTATCTAAACAATCCGATTTTTGGTTTTCCGAGGAGGAAAATTGAAACATGGAAATCCGTTTTTCTCCATTATTCGATTCTCCGATTTCCTCTCGAACGAAAAAAACGAGAATAAAGTTTCCATGACATCTCAGTGGGCTGTGGTTTTGGGATAACTTTAAGTGAAGGAATGGAGAGACTATCTAAGTATGAAAAACACGAGAATTTACTCCCTTTTGATAACCTGTTACAATACGTGGACTGTTATACTAGAAGAACTAAAGCAGTGATTCAAACATCCTGTTCAACGGTGTTCATTACAATGTATCAATTTACACCCTCACCAGTCTTTCATTTCCAGCGCTTTGTAATGTTAGTACGTGGAGATTTCCTCATTTGATTTATGATTTCTATTATTCTTAATTCTCCAAATAGCTCTTCTCCCAATAGTCGCAACTCATCAATTCCAAAATTTATGCTCAATCGAAGTGACATATGCGAATTTCCCGAATAGGTCGTTTAATCTGTCCATAAATCCATGCTCATCAACTCCAAAAATTCAATATGTCATATTCAAAACTGCTGCGTTATCGAATTTCCACATAATGAAGTTGAGTACTATGAACTATACAGTTTTTATTTCTATGAATGTCTCGACATATTTGACGACGACAGCAAACTAAAATCATTTTTTATATTCTTCAACGAGTCCATCTATGAAAACATGAATGTCATGTTAATCAGTTGTTCAAAAGCCATATATTTTACTCAGGATTCTGAACAGGCGCTCATGTCAAAAATTGACTTACAATCTACTCCAATCAAGCAATCGGGTAGGAGATCATTGAGTATAATTCGAGCATCCACTCCGCACGAAATTTCGTTTTTCTTAATCGGTGCGACATACGTAATCTTGTAGTCTTTCAATTTACCGCATTTTTTAAAAGTCTGAAAAAAATGTTACAGCTGAGTACAAAACATTAAAAATTGGGTTATTGATTGAAATTTTCACCACTTCTCATATTGTCGACCACTGAACAAACAAGCATAAAAAGCTTCAACAGACTCATAAAACACTTTTAAAGGCAAGTGTTGAACCACCTATTTTGATAAAATTGTCTGAAACACATCACAGATCGACTTTTCCGTAGCTCAAAGTGATCCTCTGCCCCTAGCTCTTGAGTGGTCATTCGAAAGTCGGGGTTTAAGTTGAAATATTTCCCTAAGCGGTCAAAATTCCATCATCAGGCGATCAAAATAAAATTGAATTTATTGGTGCTACAGTTAACACATGAAGCGGCGAGCAAAAAAACCAGGTTTTGAACAATTGAATTCAACTTACTCGAATCTAAGTGTTTCACCTGTTTGTTATCCACATTCAGTGGACATTCAGGTATAAGAAACGCAAGTGCATCGACGAAGCTGTTGCGTAAGTTCAGGATCAACTTGATTGTTAATGACTATTGATCTTTTCTTCAATTTTTAAAAGTGTTGAAACTGAATTTGTACGATGCTTCGAAAATGTTGTAGTGCAAAATCGCTGAACAATGTATTTAATAGATCAGCTGAAAAAAGAGCGAATTAGAGCAATATTGAACACAATTTTGATACCTGTCTGTAATTAGGAAAATCAGTCCGCTGTATTGATTGTTTGAAAAACTGAGTTTTTGTTAATTTATTTGCAGTGGCAAATTTTTATTATCATTTTTTTTGATAAAAGTTCATCACCAATGCCATCAGTGTTGTGGCACCACGGAGTGTGGACGCGGAAGACCGAACCCTTTAAGTCTCAAGAGGAGCCGAGCAACGAAGACTATGTCAGAGGTGGCATAGCACCAATGGCATCGTCTATTTGTATATGTATTGGGAAGAACAGACATTAAATTTATTACTCCCAAAGGGGAGATAATCAACAGAGGGGGGGTCGTACACAAGAGTGAGGGAATTGTCAGGGAATATGCACGTCCTGCCACGCGGGTCTTTAGACTAGTCTGCCAGGAAAAGGTCGAGTTAGGTATGAATAGTCGGGGTCTTTGCAGCCTCGTAGAATAATATCTTAGGACAACTACACTTTCCTAAAGGGAGGGAAAGGTAGGAAACGTCGGCAATTAGTCTGACTGGGAGGTCAATAACGGGGGGGGGGTCGGGGGAAGAGACCAAGGCAAAACCGAACCAAGAGTGGGGAAAGGAGAGATCCTTTTTTCCTGGTGCCACCGACGCTGCAGCTCGCTCCGTATCCCCCCGTCGCTCATTGAGTCGCCGCGCAGCCAATCGTTGCTACGGGGTGCGAGTGTAACTCTCTTTAGAGAGCGTGTCGGATCAGACGCAGACATACAGGTAAAACTTCTGCGACTCCTAACTGTATGGTAAGCTTAAGAGCTGGTATTAAAAGGTCGAATTGAATGTACCCGTCGCTCGGAGAACATCCTGCTGAATCTAAGTCGAGAGCGAGACTGCATTGTGAAATGGGCGATACAGCAGAGCCCAGTTCACAACTCTCCCGGGGGGCGGGACTTGTAGGCTGGTTCACGTAGTGAACCCGCTTAAGGTTCGTTGAAGCCTTCCTTTGCCGTTCTTGGAATGGCGGAGTGGAAGGTCGTACGTCTGAGCTCCTGGCTTCTTTTCGTGAACGCATTCACCTTCTTTTGAAGATCTAGTATTAGGTGAGCTCGGAGCCGGTTCTTCTCTAAATGTTGCTTCGTCTGAGCTTAAAGCTTCTTTCCTGGATTTAATAAATTTTAAAAATGGAAGGACATGTAGTGAGGGTTCAGGAAAGTCGGAGTCCGTCTCTTCGTTTTTTTGTTGAGATGATTTTTTCTTTATTGTCTATGTCTTCCGCTGTAACCTCAAGAGGATACAGTTGATTTAGTGATCGTTCCAACGTGGAGATTGAAACGAACTCCTGATTCAATGTTTCCTTCAATTGTTTACTCGGAATGAGCTCCACAATTCCCAGAGGCCATGTGCGTCTTGGCAGCATTTCTTGTCCGACGAGAACAATATCTCCTTGTTTAGGATCTCGAAGAGCATCCCTTGTATTAGGCCTGTCTTTTGTCTTTCCAGAAACAGGAGATATGAGTCAATGTCGACCAGATTTGCCACAACTTTGCAACTGTTGTTTCAACTCTGGCTAATTGTCTTCTCATTTGCTCTGTTGATCGAGTTCGGAGAATATTCCATCGGTTCGTCTAGATCAACATATTCGGTGCATCTAGCTGATTTGGTAGTAGAAAGTCGATTGTGGCGGAGAGCCGTCAGATCATTGGGATCTGTGTTGTCTGGTGTAAGTGGACGGTTGTTAATCATCCCTTGGTCACCTGTCCGTGCTGGGAGAGCTAGAAGAAGGTTAATTTTTTTGCCAATAGTCTTGCGAAGTTTAGGTGCTTCGCAATTCAAACAATCCTCTCGTACACTACCTCCTTACCAAGGGGCGAATGGAGTGATGTTGTGTACGTGAATTTCGTCATTTGGCTAAAAAGCAAATCATTGAGTAGCTTGGACTGCATTAAGTCTGATGTCTAGGTTGACCATTTGGTGGCCTAGTGTAATGTTGGTGCATTGTCACAGTAGATATGGGGCGGTACACCACATGAACTGGAGATTGCTTTGAGTGCGAGAAAGTAGTTGGCTGTAGTAGCGTCTGGAATGAGTTCAAGAAGGCTAGGCTCTAGTCTTCAGACAAGTATAGATTAGAGCATAGGCTTTACCTAGCTTGTCATCGTCTGTCTTGTATTGTATTGTACCCAAATAGTCGAGTCCTACATGGTCGAATGGTGCAGAAGGTCCAGTACTGCAGTTTTGTAGTCGTGTGTCGTAATTGTATTTAAAGGGTCGTGCTTTCACCTTTTTACAGTTCACGCACTGAGTAATTGTAGTTCTTGCAATTTTGCGATCATCTCTGATCCAAAAGTGCAGTCTTACTGTAGTGGTTGCCAAATAGTGTAATGGGAAGTAGGTATTGCGTTATCTGACATCTTCCACAATTAGACACAATCAGATGTCGGATGGGGTCCCCCCACTATCCAATGATGTTTGTTTCCGTCCTCGTCTACTGGTTTACGCAATGTGTCTTGCAAAGTGGAAAACGTCTGTTACAACTGGAGATTTAAGTTGTGTCAAAAAATGGCTGAATCAGTATGATTTTGTCTCGTCTTTGAATTCGAGATTCGGTGTTTATTGTTGCATTGACTTAGCATAAGATTTCCTGTTATATGACTCGGTGACGAGCAAAGCATGTACCATTGTTGATGCAGAAGCGTTTGACTTCATTCGCACCCATTGTGCTCGTTTGAAGTGGATGGTCTTTTTTGAAGGGAGGGCACGGATCTCCATCGAGAAATTCTTGCCAGCGCCATTCTCCACGAGTCTGGAAGTAGTATTACCCGGTCTTTTGTTGAAAATGCGGGTTCAGGAGGTTTTCCTTTGGTTTTCTGTCCCGTTGGACATCAACCAAAGTACGTCTATGCCAATCTTCCGCGCAGTTGTCAGATGTTTTTTGAGGCTTACGATTGGATAGTCAGCCCGTCTGGGTCGTATTACGTCACGCGGAGTCAGCTCGGTATCACCTTGAGAGTAACCGTATAGTCTTGATCTTTAATTATCATGTCTTTGGATTTTACGCCGCTGAATTCGGGTTTAACAGTTTCCCCAACAACAAGTCTTTAATCGTCGATAGTTATGTCTGTCACGCACAAGAAATAACTATCATTTTCTGTATGGCCAGATTAGTCGTGGTTCGTATGATATCTAAATTCAAAATTGGCGTACCTGTATCCTTTGCCTTCTCGACGCCGTCCTTGAACATCTCATCGAGGGTATCCGGCAATGAATTGGCTTCGGCAATGTATTTCAGTTTGTATTGTAAAGATCCTAAAATGATGTAATCCATATGCTGCTGCATGTCACAATCGATATTGGCGTCAATCCAGTCGAAGACTTTTTGCTTCAAGTCTTCAGTCTTAACAACGGTGCGGCGTCAGACAATGCTATGGATGATGAAGCGGAGAATGGGGTCCTGGATTCCCTTCCCTAGCTGCCACCATCCCGGAGTCGGGATCAAGACTAGTTCCCCGCGACCTCCAAGATGAAAAGTTATTCTTCGTTGAAAACCGAGAAACTTGTTATCTAAAATCAATAATTGGTTAAGAAGAAATAGACAAAATGCATTTTGAGATTAAGTAAAAGACTTAGAGATTAGGAAAGAAAGATGGGGATGAGGACTCAACTTGAGTGATAAGAAAAAAAGGCATTTTAATATAAGATTCTACAATAGGGATTGGGAAAGGTGTGCCGTGGCCTAATATAGGTTTGGTGGTACAATAAATAGGGGAAGTAATGACCCAATATGGGTTCCTTGGGGGGATTATTAAATGTTAGCCAATATGGGTGAATTATTAATTACTCATATTGGCAGGGGAATGTCGGTGAGGGCTAAGAGTTCCCTGTATCTGTTGCTTGATAGTCATGTTCCGGAGGGGACTTGTGTAGAGTAATTTGGTTTAAAGTAATTTGATGTAGAGTAAGTATTTGGTGTAGAGTAGGTTTTGGTGTAGAGGAGATTTTGGTGTAAAGTAATTTGGTGTAGAGTAATTGCTGAAGAGGAGGGATGGAGGGATTTCAACACCGACTGGTCGTGAATTCGGCCCTTAATTGGGAGGGTAGGGGACAATAGAAAGAAAGAGGCTACCGTGTGGACCAATTTCCCCCAGCAGGGACCTAGTTGGGATTGTTTTCACTTGAACACGAAAAGACAATGGGGGTTGGGAAAGTTAATAGGGACAAAGGAGCAAAACGGAACGCCCATTCCCGCATCGAATTGATAGGCACCGAACCCAAACTCTCCTGCCGCTGCAGCAGTCAGGGATCCGACGCTCCACGCTCTCTCATCGCGACTGGAGACCAAGTTTTCTCTTACAGTCTTTTTTTTCTAGTGGCGCCGGTTACTTACTCCATTGCCAACTAGCTCGAGTCGGTGGTAGAAGTCAGAAGTCAAATGCTTGCGGACGTGGAATATAGAACATGTTTGAAATTAAAGAGGGTGGTTTAAGTCTTGTTTTTTTTGAGATCCCTATGGATGAATTTTGGTTTATTTTTTAATTTGAAAGGTTAAAAGATGTACAACAAATAATTTTTAATGATGTATAATTTTTGGTGAAGGTACTAGTTGAAAAATATAAAGAATTATTGAGAGTTTAAAATTGGGAAGTGGTGTAGAAAACGATTTTGTTAAAATATATTTTTGGAATTTATGCAATTTTATAATTTTCAAGGATTTTTTAAATTTTTTAGGAAGTTTTAAAAGGGGGTAAATAATCTAACTGTTGGGTCCCCGCGTCCTCCAACGAGCAAAACCTCTATCCATCCAGAGTTCTTGTCTACCCGGCTTGTCGCCTCTTCCGCCTTTTCTTCTTGTCGTTCTAGCACACAAGAGACTGTGCACTATAGTCTTTCCGTTGCAGTCAGCGAGCCGCCAGCAGTCGCATCGTTAATGGCACCTTTGCCACTGTATTGAACGCTGTGAGCTGTTTTAAGTGCTATTATAGTCTGTAAAAACAGGAAATTTTGTACTGGATCGTCTTTCGTCTTTCGACTTGAACCATATTAACAGCCGAGGTTTATTAAATCAAGGAACAAATAACTCAACAATTTGGTATCAGATACCGGTGAGGAGTGGTGAGGGGGATTTCAAAAAATTTAACTCCAACATAAAAATTTCGTGATCGAATAACGAGATATTCGATGGGGATTGTCCTCGTGCCAATCTTGGTCCTTGGTTGGTATCGGCGTCTGACCGGCTAGTGTTGTTGCTATAGCTGTTGCTGGAGTTGGCGGAGGTCCAAATCAGTTGTGGAGCAGGAACGCGATGAGTGGTGGTGTGAACTCCTGTCCGGCTGGTACGAGTTGTGGTGGAGGTTGCTCTTCGGATGGTGATGGCGTGTGCCAGCATCGTATCCTCCAGGGAGACTTCCATCGCGAGGGATGTTGATCGTGCGTGCACCACCGCGCATCTATTCCCCTGTCGTACAGAACGACGTGATCCGAGGATTGGATCCACACTTCCTGGGAGCAAGATTGTGGAGCCGTCGCAGTCGTCGGGCCATTTGGGTCGCGGCCGGTCTCGGGGGGCTGGGCCCGTACTTCCAGGGGCAACGTTGAGAAACCAGTCTTGGAAGAACTCGGATGGAGATGTGTCTTCGGTGCGAGCGGCTCGGGTCGAACGGTCTGAGAAGATTTTACCGAAAATTAATAAAGTATATGGAAAAATTGGATAAATTTTTAGAATTTTGAAAGAATTGATTGAAAATGTGGATAAATTGAATTTTTTAAAATGAGAAAATTTTTTAGAGATAATAATAATTTTTATATCCAATTTTTAAATAAAATCGACTTCCTTCTCGAGCAGTCTGGCGCTTCGTCGATGTTACTGGTAGGATCCACTCCCACACAAGCTGTCAACTTACGTACTACCAATGAATTGCAGTATAATGTGTCTATGAGATGCAAAACGACGAGAAATAGCGAATCATAAGTCGGGGAAAGTCGAAATTGGGCTCTATATCGGGAGCATGAGTTTGCCAAACATCACCTCCCTCGCGTCTGTGGGCTCGCGAGCCGCCCTTGTGTACGATTTTAGGGGTAATTTTGAATTTTTAGACTCTTAAATTATTTTTAAAGAAAGTTTGGTAGATAATGGGACGGGGGATGCTTAAATGATGTGTACCTGTCGTCTATCAAGTCTGTCGACTATCGAAAACGTCGAGTCGTCGAAGTTCATATTGAATCGTCTCTTCACGGCCCGGCGAGGGGTACATGAGAATTCTCTACCGTATATTTGGCTGACTGCGTGCTCAACGTTGATTCCACTCAGTTTCAAGTTTGGTACACTTCACGCGTACTGCACACAGTTTAATTGACGAAATTTCGCGAAAATTAACAGAAGATTTTTTTCGGAATTACAGAGCTGAACTCTATTGATAAAAAAACTATCAAATTTTCATCGAATTTGTGAAACATCGTAAGGAAGATCTTTTCTTCACTATATTCAAGGAAAATCGATATTTCGCTTTTCACAGACGAATGTTGTCTCATTTTACTCGATGAAAGTTTCTGATGAGCTTCATCGATTTTTGAGATAAAAATGCGATTTGTTGATAAATGGATCAGTTATATAAAGAAACAACATATATTGGACACTCTGAGATTACTTTTTGAGAATCAATTCTTTATTTTTCTGTCATTTTAAATTAAACATTGAAATAAAAATATTAAATAAATAATAAAAAAAACAGAAAATCGATATATTACTTTCTCTTCGGAATTTCACCTTTTTTGGATTTATTCTGTAATAAACTCTCTTCTTCGAATTTGGTGTGTCCACGTGGCAGACGAAGAAGAATCTGCTGCACTCCTTCTTGCTTGCCCACAACTTTCTCGAATTTTCTAAAATTTTAAATTTATGGAAATTGTCATTTCACCATTCCACTCACTTCAGCTGATACTGCATTTCGGAAGTTGATCGGATACTGGTGGAGCAACGGATGGCTTCCAGTGATTGGCTGGCTTGTCGAGCAAGTTGTGTGCTTGCCTGAAATAATTTTTGATTTCAATTTTGAGTTGATCTAAAGCAGTAAACCTACCACCGGGTTCGTACGAGAAGGAGCATTACTTGGTAGACCACGGAATCTTATCGTTGAACTGCCTCCAAATGCAATAGAAGTTTGTACGTTTGGTGAGAAGTCGGGCTGAAAATTTTCAAAATTTGACTTTTCGAGAAAAATAACTCACCACAGCATTTCGAGATTTTGTCGATTGTGGAAGCCTTTTGAGTCCTGGAGCAAGAATTGATTTTTTTGTCGCTAAATTTTTTCTTTGTTGTGCAGCCGTGACGTCCCGAATAACTACTTTTGGGTCCCGAAGATTATTTTGCGAAGAGTCAGAATTGGCAGAACTGTTGCATGGGTAACACGACGGAAAGAGCGGGAATGGACGTGTTCTGAAATAGTTGTGTTTTTAAGAATGCAGAAATGTTTTTCTGTACCAAAATTAGCATAGTCTTGTCATTCATCATGTTAAGACACATGAGCTCTCCCAGAACATGGATGTAACGCCTTTTCTTGTCCCGGTAATTGCAAAATCTCCTCTCAAGTGCATTAAAAATCGCGTGGACAGATTCAACTCCTTGTTCTGTGATCCTTCCAATCTCACATCTGCCATTTGTGGTGAATGGTAGACCAACGAGCAGGTGCAGCTTTAAAATAATTGTTTCTTCGGGAACCGCTACTTTCAAATACTCCACAAATCCCCGAATCGAATTTTGAAGTATTAAGACGTGGGAATCATTTAAAAACTTGTTTCCCGAAAGTGACATAATAGTTGAAAGCTTTCCCATTGCTGATTTGTGCTCAATCCGAGCAACATTGGTCATAAATTTGCGCCAAAAATTTAGAAAGACCCATCCTACCAGCCGGCGTTAGCAGCAATTTCAAATAGTTTCCGGAAAAGGATTGGCAACCAAGCCTGCACCTTGTCCGCTCCAAACTTAGCCCAACCAGTCCCATTTTTTCAAGTCTCCCTCGGGAGTACTATTCACAATTATCTCGAGCAACAATTTTTTCGATTGAAGTGCTTTAGTTCAGCATGCGACTCTTCATTCCGGCGGCTCCTTGATACTTTTCTTCCGCACTTTTAATTTAACAGCGATTTTTAGAGTTGCTTTTCGTGTTTTCAGGATCGGAAGTAGTGTTACCTATCTAGATTATCAGAATATAGAGGTGATTGAAGACCTATATTTGTCAAAAATACCCATGATAATGCGCAGAAGAGGAATCAAATAGGATCGCAACAGTGTGTAGGAGGAGTACATCCTTTGCGAACACACGACATTTTCACAACAAGCTTTAAGATCGATTGTTCGTGGGTGGACATATGATCAGTTCTAACTCATCAACATTCATATCCTTGATTTTCATCCTCTCTTCAGCTCCACTTTGGTTATGGACTGTGCTGCAAAATCCATTTAGGAGAAAGGTGCGAAATTGTGGGATGAATGTCCTGTTTGGTGTAATATCAGATTGAAACTTGCTATCTCCAGTTTCACGGAATTTGCACAATTACTTTTGCGGTTTTTTGAACTCGACGTCTTTGTCCAAATATCAAATTTTCGTTATCTTGACCTGCTCAAGAACGTCCGCCGAATGAACTTTTTCAGAGACGAATACTTGTCGGATCCGTCATATACTGCAATTACCATAACGTGTCTCGAAGAATACGGTCGAGATACGTTTCCGATTACAAATGCCAACTTTGTGCTTCCACCTCCAGCGTCACCAACGACTCCAATCTTACTCCTTTCGTGTCTACGTCGTCCCTACAAATTGATTTGAATTGCATAGAAGCTCTATACGAAAGGACAACTGTCTGCAATTTTCACTGCACAATGGTAATCACTTTTCCTTTATTGTCGAACGAAGTGGAAGCTTTGAAACTGGAGATCATTGATACCAAATGGATTGACAAATCTGTGGTGTTTACCGATGGAAGCAAATCATAGAATGGCAGTATCGTCAAATAGTTTTTGATTATTCTGTCCATCTGACTTAGAGATAATCCGCATTGTTATTGATAAAAAGTCAACGGCGTCAAACTTTGAAGCGTGTGTTTGTAGATTTTTCTGATTCTCTTCTGAATTCAGGAATTTTGTGAATTTGGTTTCGAATAAATGGTCCGACCTCATAGGTTCGTGTTGAAGCAAGTGAAGAGCTTTGCGAAATCGATTTTTGATACAACTTCTAGTTCTTGCTTCTTAGATTCGATTAACTTTAAAAGCTGATTTTTTAAGGCTAATTTTCAACTGACTATCTTCGGCGTTACTCAGAACCATGGCTTTGCCACTTATCTTCACATCTGCACAGCTTCTCACCAATCGACCCTAAACCACTGACGATCGTTGGTATATTGTATACTTCCATCTGCACGAATGAATTAGATGCTCTTATAGTGAAATTTTCATGGCGGACTATTTGCATTTACTCTCTTCCGAAAACGCCGCAAACTCATCAATCCGCTTTTTGTAGATTATTTCTTATGATATTTCATTTTTTTCATTTTTCAGTCGTTCTATCGTTAGTCGGAGCATTTTGATCTGCGGAATTTGCTCAACATTGGAGATTTGCATATTCGAACCCTCGGTGGAACGAGTTTCGTACAGGTGTCGGTGGAAATACGGGATTGGAGAATCTCTCCAGCAATAATATTAGTTTTGAAATATTGAAAAAAATTACATTGTGAGAAGAAGTCGGAATTTCGTCATACGAAAATCCATTTCCACGTCTCTCGTCAGAATTCTAGCTTCGTATATTGAAACAATTCTGAGGACCGGCATGTAGTTGCGGAGCATACTGTAGAAGCAATGCACTCGGGATGGTTATTTGGGAGTTTCGATCCTCTGAACTGATTTCACCCTGATTAGCCTGTGGCGACGCTACACTCTGAAAATCACGTTTTCGGAGTTAGAACAAACTCCAACTTAATTAAAGTTGACAAATTCCAATTGAGCTGAACGAGCCTCCACCTTCGAATTGTTCTTCCTCTTCAGTTTGATCTTTTGAAACTCCATTAGTACTGTTCCTTGCGCTCTGGGCATTTGCTAAAAGAAGGCCTGCACAAGATTTTTCTTTTCTTTTTTGTTTGAAGTATATCCGCTTTTGTCATCTGGAAATATTGCATGAATATTTTAAGGGAAACAATTTTTAAATATCGATTTTCACGAAATTTGAAAAAATCAATATTTGGGCGCAGATACTGAGCTGAGTGTTTCGAATCTCGAATCAGCATGCTTTAATTTCCATATTTTAGGATCTTTTTAAAAAATCTGCCAACAGTTTTTGAAAAAAAAAATACTTTTCGTTCAGAATGTACTGATTTTCCAGTGATTTTCACGAAATTTGAAAAAATCAATATTTTAGGCGCATGATATTGAGATGAAAGTTTTGAGAATAAGCCAGCATGCCTTTAGATTTTAGGATCTGTTTTTAAAAAATCTGGACCAACAGTTTTCGAAAAAATTTAATTTTTGTTCAGAAATGTGAATATCTAACTATCGAAAAAAAAAATTGCAAAATCCGTCGGCTGAACATACAAAACTTATCAATTGGTGAATCATCAGCATATTTCAGTGTATAGATTAAAAACGGTTTCAAAAATTCTGAGACTAATTTTTGTTGAGAAAAATAATTAGTTTTCGTTCGAATTATCGATTTTTCACGAAATGCCAAAACATTAATCTTGGGGCCCATGCTAAAAGCCTGAGTCTTTCAATATAGCATGATTTTTTCGATATTCTAAGACGTTTGAAAAAAATCTGGACCAACAGTTCTTGAGGAAAGTAATCTATTTTTTATACAAAAATTATGTGCTGTGATTTTTTACTAAAAAAAAGAATCAAGTTGAGCCCATGCTATACGCCTAAATTAAAATTCAGAACCGCCATGGATGTATTTATACCATAGGCTCTTCGCAATAAAAAAAATCTGGACCAACAGTTTTTGAGATATGAAAAAAAACAACTCACTTTTTGACGTTTTAAGGTTTTTTCCCGGATGATGCTGTCGATTTTGGCGACTGGTGTCTTTCGCTGAAAATATTATTTTTATTTCAATTTTTAACGAAGAAAACAAGAAAAAACGACGAGAATCAAAAAACACGAAAAAGACGTCGAAAAACTCCCGCTACCTCATGAAAATAAAGCACTGCAGCCGCTGGACTTGTTTTCTCAACTTGCGGTATAGGCCATGTCCCGTTCAGAAGGCGTGCCGTGTCTTGTCGTGGCGGTGTGAAGTGTGTTGGTGTTAACGCAGCGTGTGAATACGGTAGGCTGCTGCAGATGTGGTGTGAGCTGTAAAAAATCGAAATAATTCAAGAAAAATTTACGACGATTTTCGTATTTTGAGAAGAAGAAAATTTTAGAAGGAATCACGAAAATTCGAGAGAAAAAATGATCAAATTCAGTCTCAGAAGCGAAAAGTGAACTGCTTTGTCTAGAAAACAGCGGTTGCTCGTGAGAAAAAATGTTTAAAATTGAAGAAGATCAACAAAAAAAAGACACGTAGACGTGTTTTTAAAGTTCCCGTCGTGGCCGCGTCGCCGCGCCGAGTGCGCACTTTTGTAGTAGACTCCGCCCCCTTTTTTCTTGGCGCCGTGCTTTTTAAGGGGAGCGTTTGTGGTTGAAATAATCGATTTTCGACGAGAAAATAGACTAAATCAAGACCTATGGTGAATCTGATTAAAGGCATATTAACTTTGTAAACACAATTAACTAGAAGAGGAATCGTTCTATAACCGAATATACTCAAAGGGTCGCTGACTTCCCCCGGTCTAGAGTCCCAGGTTCATCTTCGAGCTGTTTCCTGAGAAATTGTACAGGATTTGTCTGAGTCGTGAACTGAACACGCTTTTCAGGTAAACGTCGTCTGGCTGTCCTGGAAATCAAATGTTAGTCTTTGTATCGATGGCAAACATGTCTCAAGGGAGGAAATAGTCGTAAAGTCGGTCGATGCACCATGTTGTGGCACCACGGAGTGGCGGAAGACCAAACTTTAGCCTCAAGAGGAACGCAACGTAGACTATGTCAGAGGTACAGCATTCGTGGATCCAATTTGTATATGTATTTCTGGAAAGAACAGAACACAGTGTTAATAATGTTTATTACTCCAAAGGGGAGATAATCTACAGAGCATAGCGAGTGGGTGCCGTCGTACACAAAGAGGGAATTGTCTGGTGTGAGAATATCACATCTTGGCATGCGGCTTTAGTCTGAAAGGGTCGAGTTGATGTATGAATAGTCAGGGTCTTTTTGCAGACTCGTAGAATAATGTCGTCAACTACACTTTCCAAATAAAGGGAGGGAAAGGTAGGAAACGTCGGCATTTAGTCTGGCTGGGAGCTGTCAATAACGGGGGGGGGGGGGTGGGGGGAAGAGACCAGCAAAACCGAACCAAGAGTGGGGAGGAGTGTTCCTTTCGTGCCACCGACGCTGCAGCTCGCTCCGTATCGTCGATTGAGTCGCCGCGCAGCCAATCGTGGCTACTGGGCGCGAGTGTCACTCTCGTTAGAGAGCGGCGCAAGAGACGCAGAACTGAATACAGTAAACTTCTCCTAGCTGGTAAGCTTAAAGCTGGTCTTAAAAGGTCGAATTGAATGTACCCCTCGCTCGGAGAACTGCTGAAGCAGTCGAGAGCGAGACATTGTGATGGGCGATACAGTTTCAGAGTTCACAACAAACAAACTTACTGGCACTTACGTATAAAATATTGGGTTTCGTCGCGCCCCCTCCAAATGTTTTAAAACGATTTAAAACATAATTTATACTGTTTCACTACCAATGAAAGTTCATGGTTGATAACATAAATCCCCACATTTCAGAAAAATGGATAAGCAGACAAAATATTAATGAACTCATAATTTTCAATTAGCCAGCTATTGTTTCGGTGTATTACCAGAAAACAAATTTAAGTGATCTTACTCTCAACTCCAACCGAGTATCTAATTGATTAGACACATTTTTTACAATCTTAGCTGACAATTGTGCGATTTTTTAGATGAAGATTTTGTCAATAAGCACGCTGAAAATAAAAAAGCGAGGTAATTTCACGCTCGCGGAATTGTGAGCCAGTGGCTGCCTCCTTAGATTAATTTGTTACATAATTTTTCAGCCATACTTGGACCATAAATTTTGGCGACCATTACGGCATTATAATTTTGAACTGCAAACAAAACATGCAAATATATACGTTTGATAGGAATTCGCACTAAAGCTAAATTATTGAAATTCGTCAGCTTTTATTTTCATTTCTTATATTTTGACTAATTTTCAAATCGAATTATTGAAAATGAGAATTTTTAATTCATATTTCGTCAAAATTAGTGAACGCGTGAACGGAGACGGCGAAGGCGGGCCGGCGAGAGGCCGGCGTGGGAGAAGGCCGCCCGCGTTTAGCGCGCTCACTTAGCTGGAAACCCTAAGTTTCTCCAATTAAATGAACTTTCAGGTGATATACATTTTTCCTTTAGGATAAGAAAAGAACATTTCCTAAGCCTGACAATACAAAAACGTGGTTTTTAACACGTTTTTATTTTTCATAACTTAAAAAAATACTATGCATTAACGCTAAATGAGGGCATGGTAATACACAAATACCGGCAAACGGTGTTTCGCTAAATCAAATATTGAGACAGAAAAAACAAAAATATGATGAATTCTCTTTGTTCTTACCAAAATCCATCAAAATTTAGCAATTTTTTACAGTTATATTTGGTCATTACGATATGCCCATTTTCTATTAATATGAAAGAAACAATTGAAACTGATACACCTTGTCCGTCGACTATTGGGCATCGACAGATGGTCTTCTCAAAATCCAAAAAATTGGTGGAACTCTCTTGCACGAGGAGGACGCTCTGCAGGGGTCGTTCTCCTTTGCAAAGGATGGCATTCCATTCATTTGTCTATACAACCTCTCATCTTTCATGCAAACCGACATTCCCCACATACTCGAAATCCCAATTATGTAGGAAGTTCTTGTTTCTTAAACTAAAATTAGCCAACTATTTTCTAGAAATAATCTATGAAAGACCGAAATACCTTTTACCCTTGAATGACATCAAAAGTTGAAAACTGTTTTATCTGGTAAATATTCAGTCAATAATAACAGGGCAAAAATTTCCTATTTGTAAGACGGTTTGCCAGCAGCCCTACTGATGCAATGTAAGCTAGAGGTCCTACAAAAAATACCTGAATTTTGTGTCTGGAGCCTTTGCTAACTACAAATCGTAGGCAAAAGAACACATTTGTGTACAAAAAAGTATGCAAGCAAAAGAGACACCGTAGGCAGGCAAAAGATTCACGCCATAAAAGAGAGATAGCACCCGCGGTGCTAATCATTCTACTAGTGGCTTGAAGCCTCTGTTTGATAAAAGTAACATTTTAAGCATTGTTTAGGGTTCGATTTTTCTAACAAATAAAATTCATATCATTACTTATACAGTGCGTGCATGTTGTTCATTCCACGCCCAAAGTTTTTAATCATGGCAGTTTCTGAGAGTGAAATTTCAGGTGAGCAAAAAGTATTGAAAACCTATTCACAATGAAAAACCTAAACTCAAGAAATGTTGCGATTATATCTCGATGTGAAAAATAAGACAATCAAAAATTGGGCATGGCACTTCTATATGCCACCTCGGATTTTTTTATGATTTCTTATGATTTTAGACTATTAACTTTTTATTCAAACAAGTAATTCGAATTCGTATACATTCCTCAGTGCTAAATAACTATTCCTGTAACTTCTCCCAAAGACGATAGGATGATCAAAATATGGGGATATGTTCTAGGAGTTACTAATTAAACATAGTTGTGAATATTGGTTCACATTTGTGGATTTTTAGCGTCGCCGCTAAGAGGGTCATATTTGCCCCAGCCGTTTTTGGTGAAAACACTATTTCTCTTTTTTTTCGCGGTGCCATTCAAGTTGAGAAATTTCAGGCATCTCTCGAACCTGCACGGAAAGATGAATACTGCAGATAAACCTCTAGACTAGGAAAACAATTGGAAGTTTCTTAAAAGTTTGGAATTTTAATACTAGAATTTTCTGAAAAATTTCAGAAAAAAAGAGACTTTCAAGAAACTTCTGAAAACTTCGAGAAAGTTCTGGAATGTTCCAGCGCCGATTTTTCTAAAAAGTAACATATGCCGTTCCCGGTAGAACAATGTTTTGAGTATATGCCAGAATCTTACTAAAGTAAAATAGTTTGTTTTAAATAAGAGTCTGATACTCCAAAAATATTATGAAATTTCAAAAAAATTAAATTTAATAGGTTTGCAATTCGATTGAAGACCTGAAAAAATGTTAGAAATTTAGAAATTGTTCATTTTGAAAGTATTCGAAATACTGTTAGATTATTCATGAGACTGATAATGTTATCAGTTTTTTTTATTTGAAAGCTTTCTAAGAGTTTCATATGAACATCGAAATATTTTTACTTTAAAGAAACAATTGCTCCTGGAAAATTTTCACTGCGAAAACCTGGCTACAGACATCTTATGATGCTCATACACTTCCTGGACACTGAAAAAAAAAAACGTTTCATCTGCAAAGAAAAACTTAGAACATATTTCAATAATTTACTTTAGTGCAAATTCCTAGTATACATAGATGTATATTTACTTGTTTGCAGTTCAAAAAATTATAACCGTAATCAAGAATGGTCGCCTTGAGAGTTATGGTCCACGTTATGGCTGCAAAATAATGTAATAACTTGAAAATCTAGGCAGCCACTGGCTCTACTCGAGCGTAAAATTACTCACTTTTTTATTTTCAGGCGTGCTCTTATTGACAAAATCTTAAAAAAGATGTTCGCACAATTGTCAGCAAGATTGTAAAAAATGTGTCTTAATCAATTAAATACTGTGTTGGAGTTGAGAGTCACTTGGATTAAATTTGTTTCCTGCTAATACACCGATAAAGCTGGCTGATTTCGTTGAAAATTATGAGTTCATTAATAACTTTTTTTCTGCTTCTCCATTTGTCTGAAAATGTGGGTTTAAGTTATCAACCATGAAAAACTTATTCTTTCGTCAGTTGTAAAAAAAACGGTATAAATTATGTTTCACATCGTTTTTAAAACATTAGGAGGGGGAGCGACGAAACCCATAATATTATTAATACGTAAGTGCCAGTTAGACTGATGGCATTGATAACATTTATCAAAAAAAATTAATAAAAATTTGCCGCCAAATAAACAAAAACTTAGAGGTCGCCTTTTCAAACAAAAAAGAGAATCAGCCTGATACAGCGAACTGATATCCCTAATTATAGACAGGTATCAAAAATTGTGTTGAATTTTACTTTTATTCGCTCCGCTTTTTTCAGCTGATAAATAAATTGTTCAGCGAAGAAAGAGTTTTGCACAAAATTCGAAATGAGCAAAATACAAATTCACAGTTTCAAGACTTGTAATGTTAATTGAAGAACTCCAAAAATCAATATTCATTAACAATCAAGTAGATCCTGAACTTTCGCTAATTCGAACAGCCTCGTCGATGCACTTGCTCGTTTCTTATAAATGCACTGGAGATACAACAAGGTGAAACACTTATTCGTGTAAGTTGAAGTCAATTGTTAAAAACCTGGTTTTTTTTCTCGCCGCTTCCGGATCTGTTAACTACCAAAAAATTTAATTTTATTTTGATGTTGATCGAATTTTGACCGGTAAGGGAAATATTTCAACTTAACCCCGGACTTTCGAATGACGACTCTAAAAAAGAGCTAAGAGCCGCAGAGGATCAATTTGAGCTGGGGAAAAGTCGATCTGAGAAGTGTTTCAGACAAATTTTCATCAAAATAGGTGGTTCAGAACTTGCCTTTAAAAAGTGTTTTCTGAGTCTGTTGAAGTTTTTTATGCTTTTTGCTTGTTATCGTGGAAACAATATGAGAAGTGGTTATCAAGCAATTAAACCAATTTTTAATGTTTTGTACTCAGCTGTAACATTTTCAGATTTTCAGATCTTGTGTAAAAAAGTAAATGTGAAAGTCTACAAGCTTTTTGTCGAACCGATTAAGAAAAACGAAAATTCGTGCGGAGTGGATTCTGTCGAATTATACAATGATCACTTCGATTGCTTGCTTGGAGTAGATTGTAAGTCAATTTTTGACATGAGCGCCCGTTTTTATTCTGAGTAAAATATATGGCTTTTGAACTACTGATTTGACATTCGTGATTTATGGACTCGTTGAAACAATCATTTTTGCTGTGGTTGTTAAATATGTCGAGACATTCATGGAAATAAAAGCTGTATAGTTCATAGTATTCAACTTCAATAGGTGGAAATTCGAATATACCGCAGCAGTTTTTGAATTTGATGTTGGAAAACTTTGGAGTTGATGAGACATGATCGGTGACAGATTAAAAGAACTACTCATGCGCATATCTTCGATTGAGCAATTTCGGAATTGAAGAGTTGCGAATATCGGGGTCCAGAAGAGCGAGTATTTGGAGAATTAAAAATAACTAGAAATCATAAATCAGATCAGGGTATCTCCACATCATTACAAAGCGCTGGAAATGAAAGACTGGTGAGTCTAAATTGATGCATTTGTAATGAACACCGTTGAAGAGATATTTGAATCTCTCCTTTAGTTTTTCTATTATAACAGTACACGTATTGTAACATGTTCTCAAAAGAGTGAATTCTCGTGTTTTTCATACTTAGATAGTCTCTCCATTCCTTCACTTAAAGTTATCCCACAAACAGCCCACTGCGATCAATGTCATGGAAACTTTATTCTCGTTTTTTTCGTTGTTCTCGCTGAGAGGAAAAAAGCGAATAATTGGATAGGTTGAATAACGGAAAATTTCTTCAATTTTCCGAAAAACCAAAAATCGTTTAGAATATTAAAAAAATCAAATTTGATGAAAAACTCAGACACTCTTGACATGATATGCTCAGGAACGTTATAAAGATCTTTTTACAGGTTATCGGACCGACATATACGAATGAAGCAACTAGGGCGGTACGTAGTAGGTGCTCGAGGAAATTATTTCCTCAATTCATTGGTAACATGCACCCACTTTCACCGTTTTAATACTGGGAAAAGAGTTCCTTACAATCCCAAGACAGACTTGTGAATACCAGCTTATTTCAAAGTGGAATAAGGATTTCAGACTGGAGTTCCGGTTCGAAGCTTACAGTGGTCATTTTAAATGTTTAGTTCAAATATGGTCTATTTCATTTTGGTAACGTCAAACGACTTTTCGCGAGAAATGCCGTATTCAATGTACCCTTCAACACCCAACCCGTTTCGAGGGTTCTTGGAAAAAGTGGAGATCGATTTACAATTCTGAGGATATCCCGTTACTCGAAATGAACGAACAAATGAAAACGACTATTATACACAACCAATGGACATGTGTTTGCAAATGTTCAAAGAAACTGCCCAGCCATGAGTATGACTGTTCTTCCTAAAACGTATCTTCACATTACACGCCCGGAAAATATGGACAGAGTCAAAGCTAATCCGATTGACTGAACAAAACAGCCAGAGAAATGGAAGTGTCACATTCAACTACTATCAGCATGACAAAGGAGAAAAACATATTCCTCTCTAGAGGATATCCCAGACATTTTCAGTTCAAGAGCACGTCCTGTAGGTGAAAAACCACTAGGTTGTTGGTATCTCGATCGATATTTAACAAAGAAAATTTCAAGGATGGATTTGAGAAGTGACTGTCTGGTATGGAAAAAGCTTTCAAAAAATAAGAAATTCCGAAAATCGAAGAATGACTTTTGATATATTCTATACCATATATCTGAAAAAGTTCCAATGAGAGACATAGTACATGGGTGAAAACTGGATTTTTATTGCATTTCATGGATCTTATTGATTGATTTTATGAAGTGTATTTCTGTTATTACGAATAAAGCAAACAAATACACTGCCTCCGTCCAAACCATATAGCCTACGTCAGACAAGAGTTGGGCGCTGCCTAAAAAATGAAAAAAGGCGATCGTCAACTACCTCGTCGTCTCGAGGCGTCGCCGTCTTACCTGCTGAGCCATGTTGGTCGCGCGTAAAGAAGCACACTAGTAATAACATATCCTACTCATATTCTGATAGTTTTTTTTGATTAGGGGAAGTGTCAGATGTATCTGATTGATACGGTATTCTCACAGACCTTATTTCATGCGTTTTCAAGTGTGCTCACTAAGGATTCTAATAGTAAGTTCAGAAATCACAGAATTACTGGTAATTGGCAAGTTTGTTTCATGTCTTTCAATAACAGACAATTTTAAAATTTTGCATTTCAAAGGTACAGTTCAGTCTTAGATTTAAAATTTGATCCATGGGATTGACTGACTATTGTTTGCATACCAGCCGTTCGCAAGTATATGCGAGTGCTCCTACGGACGCGAACTCGAAATGAAGGTGAAATCTAAAATTTCTAAGCCTCGGAACGTTTTTCTCAGTCTTCCAGAAGTTTTTAAAGCAAATATTATATAACTAAGTTCTCAAAACTCGGTTACAAATGTTTTCGGCCGAAAGTAGACTATTTTGCAATATTTTGTTTTCGCAGAAAAATGGTACCCATCAGAGAGTGCGGAATGTGCCGAACGGCATGTGCCGATGTGCCGAAACAATTATTCCAGCACATCGGCATGTGCAGACCTCTCTTTGGTCGGCACATTTCGGCAGTCATTTCGATTCGGCACTGTCTGGAATGTACCAACCGTAAATTGATTTTTTAAAGAATTTTAAAAATGCAAAGAAACTTCAAAAAATTGATTAAAATTAATTTATCATTTCAACTTATAGTTTACTAACTTCACTATTAAGAAAACGCAGCATTTTGGGGTTATCCAACTGAATGTTCCCGCTTTTTCCTCCTGTGTCCCCCCTCTAGTCGCGATCCCACTGGGAGGAAAAATGCTTTTTCCTCTCAGACGGTTTTCGCATTTTTTAGCTGCGAAACTTCAGAACTGGGCTTAGGGCGGCGCATATATAGACTTTTTTTGATTTTTGGTACCAGACAAAGTTAAGGCCATTTTTATACTTATTTTACCAATTGGACCTGTGTTATATATGAGGTATGATATATCTTTGTGGTAAGCCAGATTCATGGTGAGTGATTAACGGCCTACAGAGTTGTAGCAAATCTCCTTCTGTTTAAAATTTTGTTAGTTGATCAATTCTTGGTATCATAGATTTTCACAGACTAACATAGCTGCGAAACTGGACAATTTCTTTATGGAAATTGCGTACACGAGACTTCTCTATTTTCCGCGTGGAGTATTAATACAAAAAATTGATCAACTAACGAAATTTAAAACAGCGAAACCTTGCTACAACTCTGTAACTAGTTGATCACTTACCATGACTGTGTCACCACATAGATATCATAGCTCAAAGTTTCCAATTCATTTTAAAAAAAACTATAAAAATTTAGAACTATTTTACTGGTCAAGCTGCCGCATTAAAAATTATGTTATTACAGCTTGGTATGTCAACAAATGTCTAACTGTGAAAATTAAAAGTAAGTTTGATTTCTTTAAAATATTTTTTGATAATTTTTTCATGTCCTGTGCAGATTTCAAATTTTGAAACAATACTTTTAATTCTCATATACGTTGAAAAATTTTTTATGACAAAGTGATCAATTAATAGCAAAGTTGTACTTTTCTTTGGATTAAGAAAAAAAAACTTTGTACTTGATCATTTTGCACATAAATTTATTCCACGGAGATATACGCATCCGAAGTGAATGAGTTTTCACTATCAATTATACTACGCGAAACCCTATGTTTTGGTCTGAAATCGCCATTGTTCAAGAATCCAAACTGAAAGAAACAACAAACATTGCAAGTAATTTTTTGTTATTTATTTAAATTGATGAACTTTTTGTTTTTTTTAAGAAGCTATATAGTATCTTTGCAAATGTGCCGAATGTACCGATTTTTTTTGGTTCGGCATGTACCGCGTGCCGAGAATAAATTGATTCGGAACAACCGCATGTGCCGATGTTATTAGCCGACATTTAAACAAGTGCCGAGCACATCTCTGTTGTACCCATCGTCTCGTCCAGATTTTTGTTAAATTCGAGTATGTGTGCGTCCAACCTTTTAAGAGTACTGTAATTTGAAACTTTCGTTCCTAATTTTCTTTGAACCTTTTCATTTTTTCCACTGGTTTTTATCCAATATTCATAGAAACCTTAAAAAGATAAAATTTTTCTAAAAATCGAAAGTTGAAGTTCCAGTACTCCTTAAAGGCACGTTACGGAATATCCACAACAAAACTTTGTCGTGGCGAGACCTGAGTATTATTACAGAGGAACGCAATAATTCGGAGAATGCGTTTAACACAACATATTTGACGCGCAAAATATCTCGTAGCGAAAACTACAGTCATTTTTTAAATGACTACTGGAGCACTGGTGTCGATTTACGGGCTAGATTTTTATTCATTTCTAAAAATTGAAGTCGGCACCCGGTAAATCGACACGACTGTAGTTATTTGAACAGGATTACTGGTTATCGGTACGAGATAATTTGCGCGTCAGATATTTTGTGCAATACGCAACCCTTATAAAGGACAAGTTCTGCTGGCCAGTGAATTGTCCCAAATTGAAATCCTTCTATTTTGAAAATTACTCAAAAGATCAAAGTGTCGATTTCGCCATTGCGCATGAGTAATTTCTGAATCTTGTTCGTTCTTTTGCACTTGGGTAAGAAGTTGCGCAGCCTTTGTTTTAGAGGGAAGTCAAACAATAGGACGTTAATTTCGCATTTGTGGCAACATAGTTGAAACTACGGTACTGTGTATGGGTACACCGTTTAAATTTTAAACAAAAATTTGTCTTGTTGAGACCGCAGAACATAGCTATTCTCAGTGTGTATTTGTCTAATAACCTGCCAATATTTGTAAATCTTTCAAAACTTCAATATTTGGCTCCAAAAATTATATTTTTAGCAAATGATCTACAAAAAGAATCCAATTTGACTGAAACTGTTAATATTTAAAAATCAAATGTATAATTTTTTTGCTCCAAAAACTGATTTTTCAAATAATCACAATTTCAATTCATTTAATTTCGATAAACACAAAAAAAAAGTATAGCATTTAAGAATTTCCTTGTTTAAGCTTCAACCGCGTAAGGGAAGGCCTCGTTGGCAATCGTCCTGCGTGTAACTTCGGCGGCGCTGAAAATTTTGAGGTTTTGCTTACATGGTATGTATTACTGATCCCTCAACTCCGCCATGCTCCGAGACGAAGTGGTATCTCTCCAGCATGGTGAACTCTGACGTGAGTCCAGTGAACCAGCCGTGTTGCAGTATACGACATCCCTCAGATACCGCAGTAATACGGATAGGGAAGGGTATGCAGATTTGGTAGACGTGGCGAGCCCTGTTGGATGTTGAGACTGACTTTTTGAAATGACTGGAAAAATAATTACAAGTCAACTTGCTGTCCGAAATTCATCATTACAAGCATTTGAATTGTTGAGCATGAGGAGATTCCGATTGCCATTCCGATGGGGTTGAGGCTCTTCCATTTCCTGAAAATTGTAATTTTAGACTTTTTAGATATCACAAAATCTGTTTAGGAAAAATACTAAGTTACAGTAAGAAAATTTTGCTCTGAATTGCTCATACAGGTTTTTAAGCTTGCACCCTGATTTGTTTAAATTCTTCAATCTTTGGATTCCTCGTGTACAAAAAATTCAATTCAGTCTCCTGGGCGTCGAATTGCGATGGAGCGCGTTTGCCGTGCGTTGGCGCAGCCGGTGGTTCAGTTGTAAGATGGGTGCAAACACGCTCCACAGAGTTTTCGATCCCCAGGAGACTGTGTCCAAGTAAACTGAGTGGTCGCTTTTTTGTTCAAAAAATGTGCCCCGCCCATTGGAAAAGCATGACCTTGTAATCGAAAATCCTTCAAATACGAATTCATTTACGAAACTGAAAAAGAATTAATTAACACTTTGTCCATTCGGTAAGATTCTTTCAGGTGTGACATCGTTTTCTCTTGTTACGAGCAATTTGGCTCAGGCACCGCCATCTGACCGGCCTAAGATAAGAATGTTTAAAAAAAGACGTGCATTGAGGAAGTTTAATATTCAAAACAGAAGAGACACATTCCAGATGAAAACAACTTACATTCTGAACGTTTCCTACGTCCGCCGATTCCTCTACGCCGTATCGATCGATTGAAAAATCGATCAGCTGACCGTTGAGCAGTACCTGGAGCGAGATGGTGATCGGAGCCACCGGTGGTGCAGTCTCAACGTCTGAAGAACCAGATCCGAAGGCATAGCTGTTCGATGGTGTTGGGTCGAATTTCTGAAAAAAGAATTGACCAATTTTTCATTTTTAATAGACTTCTAGGAAAAGGCCTAAAAAGGACAAAACGAGCCCCAACAATTTGAACAAAAGGGGTGAAATTTTATATTTTGTTAATTTTTCTGTATCACAATTTTGATTTTCAATCTATTGATATTTTGAATTCAATTTTTTCGGGAAAATATTGCAAAATTTAGCCATATTTCCTCAAAATAAACCAAAATTTGATTTTAAAAGTTTCCCTGGAGAATGAATTGTGAACTTTGGAACACCAAAATTAGCTCTAAAATTTCGAAAAAAACTGGGGAATTTCAACTTTCCGTATCTTTTAAGTTTGTCGGAATTTTTAAAAAATTTTATTACAGAAAACCACCAATAATTATAATCTTTTTTTTTTTAACCCGGGGTAATTTTTTTCGAGAAAATATCTTAACATTTAGTAATTTTTCCTCTTTTTAGGAGCTATTTGTTTTTTACTTTGATTGTTCCGTCAAAAACAATTTTAATTGTAAAGGCTTTTTTTTATGATTTTTCCAGAAAAACCGGTAAATGACACTATTACGGGAACAAAAAATTTGGAAAAAGGCACGTACTGAACATATCTGACGCAAAAATATCTTGTAGCGAAAACTACAATAATCCTTATCAAAAGGGTACTGTAGTGTCAAATTACGGGGCTCGATGTTCAGAAATTATTTTTTTGATCGAGCCCCGTAAATCGACACTACCAGTAGCCATTTGAAAAGTATTACTGACAATAGTTTTCGCTACGAGACCCTATTTTGCGCGTCGAAAAGTATGTTGTACAGTACGCAATTTCAGAATTTCGTGTTCCTGTAATAATAAAGATCTCCTGGCCACGACAAAGCGAAAAATTTTTATCGATTTTTCAGCAATTTTTCTCTTGTTTTCATAAAAATTGGGCAAAAACCGGAGGAAAAAAGTGACCAATTAATAAAAATCCCATGGCAACGAAAGGTGTTTGAAGCTACAGTACTCTTTAAAGAAGTGCACCTTCTTGGATTAACAAAATTTTGTCGTGGCGAGACGCTGGCATTTTTCCGGCGGAAAAGTCGCAAAATTAGCGATTTTGGGAATTTTTCGCGAGACAGCTGCAAACTCGACATGCGAGTTTATCCGTGCAGATGGCCAAAAGCCCTCCGTCGATCATATGACGAAGATTCCCTGGTGTTGCGAGCCCGACATTATGCTTCTGAACTATGAGATTGCCCGACTGTGGCACAAGACATTGCCCCACGAAGAGCATCGTGGATTTGGTGAGCTTCTCGAAGTCGCACGGCTTTACGAATCTGATCTTCGGAATTGAGTGGAGAGATGGTCCCGCCTCCAAGGACCTTACTCCCGATGCGCGGATAGATTGCGAAATCGATGAGCTGCCCGTTGAGCAGCACATCTTCGAGCGAAATGAAAATCGGAGCCACTGGTGGTGGGGTCTCATCGTAACGGATGAAATCCCGATGTTGAATCGGATAAAGCTGTCCGAGTCGGAGGAGGGGGTGTTGCTTCGTGGCGGTAGGGGAGAAGTAGCTTGACCGGCGGCTTTGGATTCTGGAAAATTTTAAAAAACTTGTTTATTATATTTTTATTTAAATCAGAATTTTTTATGCATTTATATTTTACCTTGTTCTTGTGAGTTTTTTTCGACAAAAGCGAGAAATCTGGGTCTAAATCGAACGACGCGCCCAGCATGTAGTACGAATCCGTTTTTACGATTCGGAGTCATTTAGACAGAAAAATGCATGAATATAGGTTAGCAGACGCTGAAAAATTGCGAATTTGGATTTTTTAACGGAAAAACGAGTGAAAATGGGACAAAAACATGTAAATTTTTTCAACGAAAATCGCGAAATTACCGCGTATCGATTCAAAATTGAATTTTTCGCTGTGGCCCGGGTTACGGTGATTTTTAAAGGCCCATGGTTGTTTTGAGACTGGTGAGGTATTGACGCGTAATTTAGATCTAAATTATTGAATATTTTTTTCTTTTTACATTGAAGAAAAAAATGATTAAAATTCGATCATTTTTTTGGGAAACTTAAGCACAATTTTCACAAAAATGAAATCACTCGCCAAAATTCAAAAATGAAGAGTTTCGTGGTGCGCCGGGTTACGGTGGATCTTAAGCATGGCTGTTTTGTATTAGGTCTCACCACGAAACTTGGAGTTTTTGATAGTTTACTTCCTATTATTTACTGTTTTAATTTTCGCTCGATTTTCACACATTTTCACTCATATTCACTCAATTTTTTGCATAAAAAATGATTCAATGGACATTGTTATGACGTATATGAGCAGCCGTTAATCTCTGCGCCTGTAAGCTTTTAGTAAGCTCCAATTTTTCTTATTCTGGCCTCAAATTATTTTTTTGATTTCCAGCTCAACGTTCACATTTTTCGCAAGCATCGCAGAGGAATGCAAACTTCTAGCTTCGGGCTCCAACGCTCGAGAATCCAGCAGGCCGCGGGGCTATCGGAGAAGATCACGGCAAGACATACCGCCAATTTCAGTAGGTAGTGTTCTTTTTTTACCCAACTACTTTTTTTCTATTTTCCAGCGTCTCCCACATTTCATCGATGGTCTTCAACAGAGAAATGGATGGCATCGTGAGAAATCGGCTCGACTCGGACATGTGATTTTGCTCGATGACACCAGGCGCCGCAATCCACAGTTGAAATCGATCGCGCTCCGCTATCTCCGCTACGATCACAGCGATCATAGAGCGTTGGCAAGGAAATCGCATCATCTCCTCCGACTTATATCAAAGAGGAAATTATGGATGATGAGCTCGACGAGGTGAAGGAAGAAGTGTGTGTTTCCGTTGGAGAAGCCGACTTGCCCACGCCAAAAATTGAACTGAACGTGGACCATCCGGAAAAGGACCTGATCATCAGCATTTCCGTGTATCTCGGCTACACCCGTACCCTTCAATACCACGAGATTGGTCTCGGACGTTTGATGAAGGTCAGGGATCGGCTCGAGCTCACCGGAGATCACACGCTTCGCGATCAGAGAAAACGCGTTCTCGTGCCCCATCGATTTCTCGTTTTCCGACGATTTTAGCGAATCTAGAAAGCCGTCGTTCAAGGATATGGCGAAAAATAAATGGCCGTCGTCGATGGTCTGCATTCTGACACGCTTTATATCGACTCGAACACCTGGCGACAAGTTTGTGGATCCGTCGATGTGAGCAAGGGTGCCGGCTAAAAGTTTTTCAGTGTTTTTTGAGCGAAAAGGAACAATTTTTTTCCCGCTTGAAAATTATTGATTTTCCGTTCTTCAGTAAAAATCCTGACTTTTGACGCCGCAAAATCGTGAAAAAACAAAAACTGAAAATTAAGGCACCGGATTTTCGGCCGTTGATAAAAAAACCGAATTTTTAGGTTTTTTCTTTTCAGAAATATATTATTTTTTGCTTGTTTCAACAAAAAAAACCCAAATTTACAGCACAATCCGAAGTTGGGCCAAAAAGTGACTACATCGGTCCGATGCACGTGCAGATGTCGGTGACGAGGATATGCGGGCGATCTCACTTGTCGGCTCGGTGCCATACGTCTACATTCATCAAGGCGTCTGCGAGCACCTCATCGTCTTCATTACTTGTGCCTGAGGTACGGAAATTCTGGAAAAATCGAAAATCGTTTTGATTTAAAAAAACGCAGATCTTTATGTGTTCTTTTTACTAAAGATTTACAAATTGTTTATGATAAAACCACTATAAAATAAGTTTTAATGATTTAATCACAATTTATATTTTCCGATTATCAATATTTTTTTTTTTCAAATAAAATACCCCGAAAAATATATATTTTCTATTTTTTCTATTTTTTGAGTACAGAGATGTATCCCCAAACGTTTCCACGCCGCATCGTCGAACGGAATTCAGAAGAATTGTGTGACACGTGCAAGGAGGCATCGGCGCAGTGGGTAGTAGCATTTAGAAATTCGGACTTTTTTGTGAAACCCCCGAATAATCTAGTTTCCGCATTATCGGAGTTCGAATTTTCGCACAAAAAATCCAAAGAGAATCTATTAAGGCAAAAATCTCAATTGATTCCAATTTATTCAGCTGGATGATAACACGACAATCTGCTTCACAACTCGCCAGGCTATCTGTTCGGCTCTTCGTGCTAAAAGGAGTTCTGTTTCGACGTGAACGGCAAAAAAGTACTGTGTCAATTTAAGGCCGTACCGTATTGCGAAAGGACATTGGCGACGGACGTTGCCAGTTCTTAGCTCGATCTTTAGAGAACGAATTTAAAAATCTGTCATTTTTTGTTGGTTTTTTTTAAATGTTTTTCCATTTGATTGTTTAATTACGATTTTTGGCCTGTAATTTGTTGAAATTTCAAATTTCTTCATTTTTTTAAATAAAATTTTTGTTTGCTAAAAAACTTATCAATAAACGGAATTCGAAGATGAGGCAAGTAGGGGGAAACGGATGAAGCGGGAAAATGATTATTTACAGAATAGAGCGCGCGCCAGAGGTTTCTCGGGGGAGCCCCGACGCGGGTTGCCGAGCTTGGCTCATCTGTCGGAAAATTAGGTTAAATGGGAGAGAGGTAACCTAGAAAATGAGAGAAATTCGGAAGAAGCTATTTTGATCAAATTGAATCCCAAATCGAAATGTTGAATTTGAAAAATAAATTTATTTTATTGATTTTTTGCAAAATCGATTCTATGATTATTGATTAAAAATCCCACTAGAATCAATAAATCTGGAAAAATCAAAAAAATCGATTTTTTATAATCATGAAATTCAATTTTTAAAGAATCCAAAAAAGTCGATATTTAAGAAATTGATAAAAAATCGATAAATCAATGGAGAGCTCGTCTCGTCGATTTGTGTCTTTGTGATTCCGGCTGCTTTTGAGTCTAGGTAACGTTGTTCCGTAAGTCTGGAAATTTTTTTGGGACGCAATGAGCACGCACAAAATGGACGGTGGCAGAAATTTAATAATTTTAAAAAATTTTCTGGATAAAAAAATCGATTTTTGCACTTCGCTTTTCTAGTGAAGAAAATTTAAAAAAAATAGCATTCAAAAGCTTGTTCAGGGTCTCGTCACGAAAAACTCACAAATGTTATCACGTTATGCGGAGCGTCGTCGAATTCCGGTGTGTTGCTATGGATCGTGTCGTTCCATGCTCAGCTTCATCGACTGACGTCGCCGTTTTCGCTAGTGGTGATCTGAGCGAGATTTATTGATTATGTCTTTAAAGACGCATGGCCTAGATAACACAACACTTCGCCCACGAACTTGATTGGTGGCCGAGTCTTCTAGGCCATGCTGCGGCTTTTAAAGGCACATAACATGATAATGACAAGATCGCCAACGGCCTAAAATGATGACCAATGCTAGACGGTTGAGGCATTACAATCAGCTGATCAGCGATGATAGGCCAGGAATATGACGAACTTTGCGTCGAAATAGAATCGATGTACTCTTGTCACGTCATTCCTGGAAATTATTGATTTTTTAGGAAAAAATCAATAATACAGTCAACAGTAACCCTCAACGAATCAATCTTGTAATCCGGTGAAATCATAGAGTAATTGCGTGAAAATGCGGCTTCGAACCTGAAATGATAAAAACATTCATCAATTATCGATTTTCTTGAAAGTTTTTATTTTGAAAGTTTTTACGCCGAAAATCGCGATTGATACATTAACTTGATAGATTTCCCCCCGTCGGAAAACCTATGAATCAATGAAAAAGTTAATATCTACATTTTTTCGAAGAATTGAACTAAAGTCGATTATCCAGCAGAATATCGATTTTACTAATCATTTGAAAAATTATCATTTAGACGATTCCTACGGAAGCCCAGAACAAATCAAAAATCGATAAAATTGACTATCGATATTATTCTAATTTTACTTTTTTCGATAAAAGTCGATATCGTTGATAATCGATTTTTTAGAGTTCTCCTCAAAAAATGGTAATAAAATATTTCTACGAACTCACACATTAACAGCCATTTGAGCATCACCAGGTGATTTTTTGCAGGTTCTTCGGCTCCGACAACCACTGATCCTTTCAGTGACTTGATTTCAACATTCACTCGTCTCCTGAAATGGAATTGATGAATTCTCTGATCTGGAAAAAAATACAATAATTGTTTAAAATTGATTTTTTTCAGATCATTTTTAAAATAACTAGTCTAAATCTATATTGAAGTCTAACTCAGCAAAATTACCACAGGCAAAGGATACGATTAGGCTTAGGCTAAGGCTTAGGCTTAACAGGCTTAAGCTTAGGCACACGCGAGATGAAAACAAAAGAGTTAGTGAAAACAAGAAAACTTTTATAAAAAAGAAAAAAAAAAAAAAAAAAGTGCAACACGTCGCCAAGCAATTCTAAATAGAACAGGTTCAAATACTATCTGTGACTCAAAAATCAGTTTAATATCGAATTTTTCCCACATGTCAATAATCCATTATCCATTCACCTTTGACTCGCTGGCACGCACCAAATCTATTTCTCGGTACCAGGGCCACTCTGAATATCGTTGAACTCCTCTACAAATTTCCAGTTAAATAATAGTAAAACTATTGGTGTTCGAATGGATTTAGCCCGAAGGAATACTTTCGATGTTTTGAAGTGCCACCGGCACAGTTGAAATATCTTCAAAAGTCGTGGATTCCTCTGATGAGGTGGAGGTGTTCGGAGGAGGTAGTGACGTCAGTGGAGAGGGTTTGGCTCGGGTTTCGGCCATGGTGGTGTCCATTGTGGTTTCCATAGTTTTTGTAGTTTCCTTGAAGTTCATTCTGAGGATGAAATATTTGTGCGAAGTTTTGCATTTGTTTTTTCCTGCAATATCTGAAGACTTCCGAACCAGCAAAACTCACTAGGTAGTGTTTTAACTATACGGTGCGTACAATCAAGTAAAAGTGTCATGCGAAAGCTGGCAAGGCTTTAAGAATCTGTAATTTGTTCCGGCGGAAGACCTCTGTTGAGTCTGGAAATTTTCATCTGAAAGTACTGAAATCTGCATTTCCTATGGATAACAGTTTTGTGTCTCTGGCGCCTACAGAAGTCGCACCACAATGGTGGAAGGGCGAAAACATCGCTTCGAAGCTGTTAACCATAGGAAATGCAGATTTCAGTACGTGAATTTTCGTCTCAGCGGGGATGAAAATTTACAGTCTCTGACAGAGGTCTCCCGGCGGAACAAATTACAGATTCTGGAAGCCTAAGATGCCAGCCTTGCTATCGCATGAACGATTTACTTTTACACGAGCACCGTAGAGTTAACACTCCCTAGTCAGATATGTGCTCTACACTTTTAAATTTTGAAATCAATTTCAACTTGAATATAAAATTAAGAGATTTTTGAATTTACTAGGCCACCTCGAAAATTTCCAGGCCACGGCAGGTTGGTAAGGTGAAGCTGCAGACCCCATAAACCTGTGATAAGTGAACGCTTGCAAATTTTTTAAAATCAAACATTTGTGAAGAATCTGAATATTATCAGAACAAAAAATAATTTCGACAAATAGTAATAAATTTTTTTATCAATATAATTTTTAACTAGTTCCCAAAAAACTCAAAAAAAAACTCACCGAGACAGTCGTAGTGCTCTCATCTGCCTCGTAGTTTTCCGGGTATTCGACAAAATATTTGACTCTTCCTCAGACATTTTCAGAATTGGGAATGGGGGGCTCTGACCTGTGCTCAATTAGCTTTCAATAACACTTCCATCCTGCTCAAAAAGTCCTTCCAGTGCACTTTGATCAAATGGGGTTTCTACCTACAGCTTCTGATGGGTCGCTTACTGGTTGGATGGTATGGGTTTTGGTCACCTCTGTCTAAAAATTGGCAATTTGGAAGAGAAAAACCGCCTCGGCCATTGGTGACGTCATACTTTTGCCACTTCTTCGACCAGCTATAACCCGCTTTTAGGAAGTTTTATTTTTGGTAAACCAAAGAGACCAATTTTAAAACTGTGTCTCCACGTTTACCGCCAACTTAAGGGCGTGTCCGTACAGGGTTTGACCGTTTTATCGGGCGTCTTAATAAATCATTTTCAAGTTTTCAGTTTCGTGGAAAATTAACATCGGAAATTGAGTCATCAGGTATGACGTCCGCTGCCGCGCGGCTTCCCATCACGTCACTCCATGCGCTCCCCCGACGTCCCTCTAAGACGTCACCACCTCTCACCTGGGTGTGTCATCTCCTTCTCAAAACTCGTCTATCAGTGACCTCGTCCACCCAGTCAATCGGAAGGGAGCTGAACGTAATCACCCCGCCCACAAGGGAGTGGTTGGCATCATTTCAGTTATTTTCAGCGCCGAGAGTTTTCTCAGTGGTCATCCTGATCCTCCATACTATCATCTTCGATTCTTGTGTGTGTTAAAGTTCTGAACATACCGCCGTCAAACGGAGTTATTGGCTCTAGGAGAAGACCGGACGTTTTCTGGTTGGGTTCACTCCTAGGGAGGTGTGGTTCGGCGAGAGATTTTTCGATCATTTCTGTACTTGTCTCGAGGTCTATCCGATATGAAAGTTATGACACATATTTTTGGTGGCCTGGGACTAGGCCTCCTGTCAGCCTAGAAATCTCAAACCTCGGCCTCCAGCCCTCACTAGCTGACCTAGATTTGGTAAATTACTAAACATCGGCAAGACCTCTTTTCGACTACTCCCTTACAAATTTAACAGTTTTTCATCACACAATTTTCCGATGCTTAACACTCATCATTTCTTCATTCGGAACAGCCAACCATATCATCATTATCAGGCATTACGGTGTCGTTGTGTCTTTTGCCAGCTGTTTGTCGAACACTTCTTCTGAATTTTCGTGTTGCGCGAAGGAAAAAAAGTTAAATTACATTTTGTCTAGGCCACCAGTTTTTGCATTTAACTTTGGCCTAGAAAATGAAATGAGAAGCTAGACCATGTGGGTTTATTGCGAGGAACGCGCAAGCTTACATATCCCACGAAAACTTTTATAAGCGTCTAGTAAAGTAGAAACCTCGGACCAAGTTTTGCACTGTGACCTAAACAATTTTGGTAAAATAGCAGCAAAATTTCCATGATGGCCTCAGGAAAACTAGGCCAATAAGGTTTCTTCCGGTACCTATCCGTTTTGTAAACCTAGGTCACCAGTTACTAGGACAAGAAAAAGCTAAAAACCAACATTTCAGATTGGTCTGCAAAAGGGCAAAATATAAGCCACTAGGAATGTTTGCATGGTGGTAAAATATCGTTGGACGTGAACCAGAAGTTTATCGGTCATCAACTTACGTGTCGTTGAAAATGCAATGAATAGATAAAACAAATGGTAACACTGTGCATCGCTGAAATATTGCAAAAATTAATTTATATTTTGGAATATCAGAATCGGAGAGTTCATTTTTTTGGGTCAAGATAAAAAGAGTGAAATGGAGAAAATTTATATGATATATCAGGTCAAAATGACCTTCGGAAATTGGGAAGGAGAATAATCCAAATTAATTCGCGTGGAACTGGTTAAGATGATCGAAGATTGGAGCGAAAATTTTGACAGAAATTGCAACAATACTAATGCAAAAAGTTGTATAATTCTTTCAGTTTTCAGAAAATCGATAGCAAAAGTCTTTTTTTTTAAATAATTCAACTGAAATATTTTCGCTGCGAGACCTAAGGTTACAAATTGGATTAAAAATTTTATGTGCCCATTAAGAGTTTTTCTGGAAACTGAAGAAGTCGAAAAATCTATAATACCCTACTTAAATTTAAAGGCGCACGAATAATTGAATTTCCAGAAAAATAAAAAAAAACACACAAAATTTGATACTCCAAGTTTAGAGATGCATGGGTAATCAATGTGAATGAGAATTTTGTTAAATTTTTGAACTGCAATTTCAGATATTATGAGAAAGCACAAAATTCGAATAATGCGTATTGCGCAACATATTTTGCGCTCAAAACGGCTATCTCGTAGCGAAAACTACACGTATTTCTTTAAATAACTACTGTAACGCTCTGTGTAGATTTACGCGCATCAAAAAGTATTAAGATCATACATTGACCGACAAAATGTTAAAATTAGGCAAAAAATAAACGAATAATGAATTTCGTAAATCGAGCACGTAAATCGACACAAGCGCAGTGGTCATCAAGAAAAATCACTGTACTACGCGTTACGAGATATGTTGACGCGCATAATATGCTGCGACGCATTCTCAGAATTTTGTGCGCCCGTAATAGACCATTTGTAAAATGCTTAAAAACTTCAGATTTTATTGAAAAAAATTTCTATTTGAGCAAAATTTTTCGAAAAACAAATCTCGGAAATATATTTTTCCATCGAAAAAGTCTCGTAAGGTGTGCTTGACATAATCTTGGTAATGGCATATTTTGTAAACAAGGTTACAACAACCCCTTCCTTCAGCCCACCCGCCCGGGAAGCCTGGGCATGGCGCAAGTGCTGATGTTTTGTCTGTTGTTGCTTATGTATATGCTTATTATTTACACATTTGTGTGTGTGTGAGTGACTACACTGCACACCTCTTGAAACGGATTATCCGGACGTGGTCGAGCAACGGAGGGACGCCGAATTATGCACAATGCTATGTATTGTGATATGAATACTTCATTTCAATAACTTTATATATGTTAGCACACGATTTTTGAAAATTGGGGTTGTGGAAGAGATTTTCACACTGGCCTAAAGTTTTTGAGTTTACTTTAATACTTCTAAATCACGTGGTGTCGGGCGGTCTGCTGCAATACTATTTGATCTACAAAAAATGCGGGCATTTTTTCCCAGAAAAAACGTCCGCACGCTCTAAACCATAAAAAATCGAGATCTGCGTCTCAACTCCCGTATTTTTTGAAGATCAAAGCGAAATGTTTCTGCACTCCACGTGCTAAATGAATATGAACGTTATAAAAATTATCTCTGGAAATTTGAACAGAATTGCTCCCCCGGGTGGAGCGCGTTTGCCGCTTAGTAGCTGAGAGACTTAGCTGCGCCGTGAAGGGAGGGAAAAGTAAGGAAGTTATCAAAACCAACAGACGCACTTATGAAAAGGAACACAAGAAAGAAAGTGTTCTTTTTTCGATTTTTGTGATTTAGTTCGTGTGTGATAAAAGTTCAAATGGCTCGGTAGGACAATAGGAAGGAAAGTGGAATTTTATATTTCATCTTTTGTTAAAATTTACTTTTGTAGGTGTATGATTAGGTAGTGTTAATAGAAATCGGGACTCGCGGCTTTCATTTTTTTGTGGCCGAGTATAAAAATCTTCCCGTCAACCATACGTGTTAAAGGTAATCAATAGGATATCATATTGGTAAACTTTAACAGAAATCCTAAACCTAGGTTTTCCGAACTATGGAGCTCTGAAGTAGGCCCCTTTGGGAAACATAGGCCACCAACCTGAGAAAGGTAAGGTGAGGGCAGGGTGCATAAAATACAACTTTTTCTCTGAAGTTTTTAATTAAGCGAACAAGCCGATATAAATTTTTCAGTCATGGCCTGACTTGACATTGGTGGGCGGATTTTTTCGAAAAAACTCTCACGATTTAGAACATGAACTTGGCAAAACTTCAAACAAATCCTAGAGATAGGTTTTGAATTATGAAGCTTTGAAACTTCTAGACAGGGGCGTTGAAAAAGCTACCCCTTCCACTGTCATAAACTTATAACAATTCACAATTCGGCAAACAAAAGTAGAGATTTCTTTCATATGTAGAATTAGCTCAATTTTTCAATCCATTGCACGGCTAGATTTGAACTCATAATTTGAAATTTTTCGGCCACGCAATAGAAAATTCTAGTTCATGGGAGTTGAAAGCTCGGACAGGAGCTAATTTTAAAAGCACAAGAGACAGGAAAACCAAAAATTTGTAAAGTCATAAAAATCAAGTTTTTTAGCTATGAGAAAAGGATTAGAATTTCAACACGGCCACCGATCGCCGGAGCGAAGATACAATCATTTTGGGCATAGACGTCGTTTGCGCATAATCTTTCTCACCAAAAAAAGATTGAAATCTTTTAATACGAAAAAAAGTTGGAAAAGAATTAGAAAAATGCTGAGGAGAAATTTTTTTTATGAAAGCTTAGGCTTACAATTTTAGGCTGCTATTTTTTCAGTGTTTTCCATGTGCAGAAAGGAAGAAACCGATCCCGACTTTCTATCACACACTGAGGGGAATTTCACCCCCCCCCCCCCCCTCAATTCCCGCTACTACTTTTACTGTACACTCTCACCGAAAAGATATTGTGTCATCACGCATCATGCCAAAAACGCAATCGTACAACCAAGGAGAAATAATTGATGAGAAAACGCAAGTGTTTCTTCATACACTACATAGTGTTCAACACCCCTGCATGATATGGCCGCGTGAAAACTCTTCCACGGCCAGGAGTAAAAGAAAGTTTTACGGAACAATCTAGCAAATTTTCATAACAATCGGTTGGGAAACTAGTTACAGGGGTTTGAATTTTCTAGGTGGGCCATGCGGAAAAAAACTAGGTTCGGCCACGTTTTGGTTAGGGAGGCGGTGTCTTCAAAATAAATCTATATACACCTCGCACCTAATGATCCGCCCATGAATCTTCATACAGGGGGAAACAATGAGGTATAATCTTAGGTGGCCGAACTTTTGGTTCGTGAAGAAATCTCGGCCAAGACCGCGAAAAACGTATTCTTTTTTTGAATCGTTAATTGAAAAACTGAAAACAAGAAGTTTCTAGGCCATGTTGCTTAACCTTGGGGCAGTAAATATTTTTCCTAAGCCATTAAATTACTACACTGAAAAGGCCCTAGGCGCCCACGGCTTCAAAACATAGGCCACCAAAAGCTGAAAGAGGGTTAGGACCGGAGCCTGCTATTATGAAGCAAAGTGTTTGTGGAATAAAAAGTTTCAGAATTTCCACCAGTTTTTACAAACTATTTTTTCTCTGGAAATTATAAACCTGAAATTTCGAAAGCGGACGAGATCGTCAAAGAAAAATAAGACGAGCTTGCAATTCGGAGGGCCAAAAAATGAGAAGAATTTGAGAACAAGAAGAGGGTATGACGTTGACCTATACGCGTATTGTCTTTTTTGTTTTCCTTCTTCAGAATGTGAAAGAGAAACTGTCATAGCTAGTCGTAGTTCTTCGATCACCTAATCACGTTATTGCGCCCTTCGAGCACAGTTTTTTTTAGGAAATGTGTGAAAAATACACATTCTTTGCGCTAGGAAAAATTGTGGGAAAATTGAGGTTATTGAGGTCCCTTGCCACGACACCGTGGCCTAGGATACCGCCGTGCTCTTGAAATCTCGCTTGTAGCCTAGAAAGTTCCCATGGTGGCCTGGAGAAGTTTAGCGGGGCCTAAGACTTTTAATTGTGAGTGAGTTTTTTTGGCCTAAAATGCTATACGTGGTTAAAATTCCTCATTGTTGAAATTTTTAGCGCGGCTTAGGATTTTCTATAATGGCACTGGATTCTCGCCGTTACCTAGAATTCCGTAATGTGGCCTGAAACTGGAGTTTAAGGGTGAAAAGTTTAAGTATTTTCAATCGTTGCCTTGAGATTTTTTACAAGAATTCCTCATTGTGGCATTTTCTATTCTGGCCTAGAAGTTTGCATCGTGGCCTAGTAGAAATTTGCAGAGCTTGGTTTTGAAATTCGGTTTGTTACCTAGGGTGCTATATCGTAAATTCTTCCATCATAACGTATTTCACATTTTGACCTGAAAATTCTTTGCGTGGTCTAAGATTTCTCATTCTAGGATATTCTCGAAGTTAAAGACACTATTGTGAGAAAAAGTTCGTCATGGCCTAGAAATTGCTCCCGTGACCTAGGAAGTTTCAAATTTTTTCAAAAAAATTTCACCAGAAATTCATCAAAATTTTCAATTACGGAAAAAGAATCATTAATGATTAACCACTGCAACTTTTTTCGAACTAAGGACGAGGCAAAAAGATTAGTACACTAGGCCATGGCCGAGTTCCCGACAAATTTCAGCGGCCCACACGTTTATTTTGCTTTGTTTCTTGGTTTCTCTCGTTTTTCACCGATTTTTTCCGCATTTTTTCCTATCAAAACTAATAAATAAATTTTGGAGATGCTAAAACAATCAAATAAAATTGTGAGTTCAGTCGTGCTGGTCAAGTAGCGGTAAAAGTGGTCAATGTAATATGGATTACGGCAAAAAAAAACCCAAACTTTTTCCCTAACATGATACATATGCTGTTTAGAAACGGGAAAAATCGTGTGAAAACAAGAAAACAAAGCAAGAACTGTCGTAATAATGCGGTGTATTGTGTGCAGACACCGATTTTTCGCATTTTTTCTCGGCCCTCGAATTCGTAAAAAGTAGCAGTGTTAACGGCGGTAAGAGCTATACCTACAAAAGGTGGCCACAAAAAAAATAGAAGAAAGGATCTAAAAAGAGCAGGGAAGAGTTTCTCAATTGGCCTCGTTATAGAAAATAAATACAATAAATATGTTTTTTGGAGAATTAAAAAAACAAAAAAGTTCAAGAAAAATTTAGAATATTTTTTCAGTTTTTTTCCTGATATTCATTAAAATAGAATAAATGGAAGTTCCACAAAAAGCAGGAAGGTGAGCTAAATACTTTAATACACCTCCTCCTCTCAATTCTTCAGAAAAAAGAATAGGCTTCTCCTCCTCCCACCTCCCAGACACTTATCAACACTTTACCCCATTCCTCCCGGCCCCCGGCTTTTTCAGATTTTTCAACCTTGAAAATGACGAACATTTCAGATAAATGTTTCTGAGTGTTATCTGAAATCAGGGTGTTGAAGCAGCCCCAACCGCGTGTAGCGTGGCCTAGAAATCCGAAAAGTCTTTTTGATCTTCCGCTTTCTCCAACTAGCAAGTTAGGTCTTAAGTCAAATGGACTCTCCATGACCAAGTTATGACGATTTGTAGTTTCTAGGCCATGGAGTGCTCTCCGAGGGGCTGAGACTTTGACCCCCTGACGCCGGGATTTGTAGGACTTTTCACCTGTTTATGCTACTGTAAGCGAACTATATACGTTCTTCACGCCAAGATATCCGTCAAATTGTGACCACCGTTTCAGCACTTTAAAATTTCTACTTGCATTCGCCACGCTGTCGCCATAATGGAATATTTTTCTCACGAGGAATAGCATAAATTAAAAAAAAAACAGTCTTCAACTGGCCGATATTTGGAAAACAAATCCTAACGAAAATGTTGCAGAATTATTAAAAGCTTAATTAAAACAAACCACAAAAGTTACCTAAAATGAAATAAAGAAATAGGCGTACAGAATTATAAAACCTATAAGCATGGGTGGGTCACAGGTAAAGATTATGGAAAGTTTTTGAGGGAACGTAGGAAGATATTACTGTAAAGTTATGGGGGAGAAGCGAGCGGCTGAAATCAAAATGGACTCGGTTGAACGCGTCGATTTGAATCACGGAGAATCGTTTGTAGGGCTTCCAGATAAAAAATGTTCTGCCTGCATTGTTGGGCCAAAACACATGAATCATTCAAAAACAAATTGGCATAAGAAAATACATACTTCTCCAAAAAAAATCAAAAAATAGGCGATAGGTTTTTAGATACAGTATAATTTGAGCAGTTAAACTATTCACCCCCTACAACTGGCGGGCCCGCAGGGCCTTCTAGTCAGGCAAAAAATATACGGCCCACACTCACAGCAATAAGAAAAGTTAGGGGATAGTAGAGACTTTTACTCAAAAGGAAGGCCGCATTACACAAATGTTTAAACATTAACCTCAAAGCGGGAAATTTTTTTTAATGCGTACTGAAGAAATCGACGTAATGAAACTCAATTCCTACCACCCCGTAAACCTCCTTCACGTCCAAAGTAGTCCATAGTGACATGAATCCTTCCGACCAACGTAAAGATTGGAGATGACGAAATTTAAGATGTACCAGTATACTGGTACATACAATTTCTACGTCACAACATCTTGACAGTCTTTTTCCCTCAAAGAGATGAGCCCCTTGTGAGATACAAACGCTGCGTCCTATCGTGGGTTCAGTTGTGGTGAAAAATTGTAAAAACTGTAAGTACCAACTATGCTGATATGCCAACTACCAACCAGCATAATTGGTGCCAAGAGACTTTTGCCACCTCGAATCTGTATGACGTTGGTCGGAAGGCCTTTTGTCACTATTGATTAGTGGGAGGCTTACGGGCTTGAAACAATCGTTTATTAAAAGACGTATCTTATTCAGTACGCAATATTGGTTCCCAGCAGTCATTTTTTCCGCTTACGTAGATCTTTAAAAAATGCTGGAGAAGATATGCAGTGTTCTCAACTAATTTCGCAGAGTTAAGAACGTGCTGACGTCACTTAATTTTTTTGAGCAAAAAATTCCGGCATTTTTTGTAGTTCATTCATATCCGTAACCCTTGGACAGCCTGGCACCACGTGTAAGAGATGTACACGATGCCTTGCCTCTATGTTTGCCCGGGAGTGTGGGAAAAGTTGTAAGCTGTAGAAAAATGGACAACAAGCATGTTGTCAGTTATCGCAGCATTTTATAAGTCAATGACAAGTACAACAGAGAGCTTAACTGAAAAGTTTGAATGGAAAACTTTCAAAAAACAGCGAAGGTTCTTTGATGGATGCAAGGGCAGAAAGTGACTAATGCATGTGTTTGAACTTAAAACAAATTGGCTAGTCTTTGACTGAAACTACCTTTTATAAAAATGAAGAAAATGAACCATTACGAAAATGTTAAACTGAAAGTTGGTGTGTTTTTATTGTCGTTCTGTAATTAAATTCCTTGAATGATCGCTCTTCTGCAAAGAACAACCACAAAAAATAATTCGATATACTCAAGTATCGACGACTTTGATTGGAATGCAAACATATAACAAATTAAAATAAAAATTCTACGGTCATTATATTTTAGGAAAATTATTGGAAATTTTTTAGGCTTCTGAAGTGTCAAAAACTTTCAGAACTAGTAAACACGCAACATTTTATATGTAATAAAACACTCAGCGAGTTTAAACTTTGCAAGACATTTTGGGACATAATTTTGGCCTTTTAAGAACAATTAATTGGAAAATAAAATAGTTAGAATGATCGTTCTTCAAACAACCTGACATAACAACAACACACCTACTCTGTTATAATAAGAAAATGTAACTACTCATCCGAGTTGTCAACCTGCAAGACCGCATAAGTTTATACCACTCGAACAAAAAACAGTCTTCGTTCTCTTTCTTGAAAAGAGACATAATTGAAATGAACTAATCACCGCTGCCCGGGATGGAAAAAAGAAAAGAAAGTCCTATCATCCTTTGACCTTGTTATTTTTGCAAATCATGTCTGACTAATACACTTTGTGTTCGATACATATTTCACTGAATCAGGCGTGGGCGACAACCAATTTTTACGGCAAATCGGCACATTGCTGGAAAATTTCCGGCCTTGCAAATCGGCAACAAAAATGTTTGAAAATCGGAGAGTAAAAAGGTGGAAGTCACCAGCAGTGAAGTACCTACTTTATTTCACATGAAATTAAAGTATACACCATCTCTCTTTTTTTTCCTTATTTAACAGTCTTTGGTCTGTGTTCTGACTGTTGAGAGATCAGGGATCATGGACGAGTTGTTTTTGGGAAAACAAATTCTTTTTGGACTCCTTTAGTTTAGTAAACGAAAAATTTAAATTTATAAGCATATAAATATTTTTGTGGGAATTTGAAAAAAAAAGAAATTAAAGAAGAAACAAAACTAGTGTTCAACATGTATAACTGGGAGAAAGAAAGAAGTGCGCTTCCAATTTTCAGAACTTTTGCAAAATTGTAGAAAGTAGTTCATGCTTCAGATCAAAGTTGTAGGAAAAAATGTGGCCATCCGAAAGAGAAAATTCTGCCACGACCAAAACTCAGCACTAGACTGAAATTTCAGTAGTAGCTGACAAAACCATCCAAAAGATATTGTAGGTTACAATATCTACCGTGAAAATTAGAAAACTCGAATCAGATATCCGTGGGCAAAGCGAAAAAAAAATTAGAGTTTTCTAGGCCATTCGAAAAACTCGTCCACGTGTGCATGAACTGTCAAGTCGCCAACGTAAAAGGTGTGAAACCCTTGAGAGCACTGAGAAAGAAATGAGATAAAGTAGCAGGTGAGACCTCCTGTCTCTGAGAAGCAACGTTCGAAATTCTTTTCCCTACATTCCATCTATTATCATTATTATTATTATTATTAGGACGGTATGGAGCCAGGAACTGGTTGTTTATACTGACCACTGCCTCTTCCCGATTAGGATTATGTGATTCGGATTTCGGGAATTGAGAATGGCAGATGGTTTATGTAATTTAATCATATTCCTCAAAAAGTTAAGAAACAAAAGAAGGAAGATATAGATCGCTGAATCAGTGAGGAGCAATAACATAGCATATATGGAATTGGTAAGACTGGTTTACAGTTACAAGGGAAAAAAATTTGAAAGTATTCGTCATCTTATCTAGGTAGTTGAGACACTTGATTACTCAGTTGAATGAACAAATGGATGAATACAAGTTCGTATGCTGAAAGCATCTCTAATAACATAGTATTGGTTTTAAAGGTGGAGTACGGTCGTGGTTTTAACCTAACTGACAAAACAGTCCCAATATACCGTAACTGTTAAAGATTTATATAAATTTATTCTGGCAAATTGTTTATAATTTGTAAAAAAGTTTTTTTTTTAATTTAAAAATTTATTAATTTCCAAAAAAATAGTTGATTCAAAACTAAAAACCCAAATTTTCTGAAACTTTACCAGTTTTACTTATTGTCTTAACAATAATATACACATATTAACGAAATACTCACCGTTCAAAATTTGACTTCTTGAAATCTCCAGTTTTAACGGCAATTAGAGAATTTGTTCAAAATTCCAATCTCACACCGAACGTTTTTCTTCGTTTTTCATTTTAAAACAGTTCTATCCAGTTTAAAAATTTACCAAATAAAAATGTGTCTATACCTCTCACCACCAATCCCGTGCATGTGTTCATGTTTACCTTGAAAAGTGTGTATTACTATATAATACAGAACAAATATCAAATGGCCACTCTCCTCCAGCAGAAGGAATGCTTAGGTGTACGAACACTGCAACACTTCCTATTACTCTTACTAGTTTTGCGCAATTTTCTGGTCCTTTTATGTAATTTTTTGTCTGGAACAGGAAGTTTTGTGTTGTTTGGAAAATTAATGTTCTACGTGAGATTTTTAAGTGATTTTTTGAATGGAATTTCAATTCATTATTTCATTGCATTTGTCTTTTTTTCTCACCGAAATCCACTTTTTTTATAGAAACAATTTTTTTTTCTACATTTTTTCCGATTTTTGTCATTCAATTTTTCAACTTCTCCATTTTTTCTACAAAACACCGACAACTACAAAATACCTAAAAATTGCAAATTAAAACAAATTTAAACATTTTTGCCGCAAAAAGTTGTTTTTTTTTACAGAACATCTAAAACTCCCTTAAAAATATGCTAAGTCATTTTTCTGAGAAGCACTTAATTTTTCGATAATATTATTTTTGCTATATTAAATCCAGAGAAATTAGAAAAAAAGAACGGTTTTCTACAGTACCTACCCTCCCTCTCCCTCTTAAAATCATTCCTACAGTGTTCTTACAGTAGTCTTACCTGCACCACTCCTACACTGCTCTTACAGTGATCCGATAATACTTTTATATAACCACACACTCCATACCTATACCTTACACTACAGTACCCCCGCCGTACCCGAGGCCCCCCCCCCCCCAGTACCCTTGCCACTTCAGTATCCTACATTATCTACAGTTCTCCTACACTACCTCTACAGTACTCCTACAGTACCATTACCAACGAGAAATTTGAATAGAAGTGAAATTATGAACATTTTTTCCTGTATACCAATTTTTAAAGTTTTAGTTTTGTAGTTGTTTTTGACAACGTAATCAATTTCAAAGTATTTTTCTTTAAACAATCGTACTTTTTGCGTACCGGTGGTTCTTGCACGGGGATTTTGGAATAAAAGTGCCCTCCGAAAAAAGCGAGTGCGGAATTAAAAGCACAAAAACCGGATAGAATGAGGAGGTGCGAACGATGGAATGAAAAAAGAAGCAGAAATTAGATTTGGTTCAGAGAATTCTGTTTCTTTTATTTGTCGAGATTTTGGTTTTGGAGTCTTGGCAAAATGTTTTATTTTTGTCCAAGAGTCCTAACGTTTTTTTCCACCAAAACTCCCAATTTCAAAGTTTGGAAATTTGATTCATCGATCTGCCAAAACTTCCGATTTAGAGAAATTAAATGTTCAGTTTCCCGTAACAGGGTTTCGTATCAAAACGAGTGTGAACCGCCTACCTATGTTTTTTAAAAATGATCATACTCTAATTTCCCTTCAAGCACTTTTTTTTTTGAATGACTATTTGAATATCCCAGAAAATTTTAAAAACGTCATGAGTTTTTTGAAAATTCAATTTTGCGTGTTCCTGTAAAAAACCATAGAAACTGTTGACCTATAACCTGCCCGACGTTCTTCCTGTCTGTTTATACCCCATCCGCTCTGCACTCCAGAGACCCCTCGTCCTAACTACACTGATTATTAAACTGTTACCCCGCCCCCCCCCGTTTACCCCTCATTTGTTTTTTATTCGGTAGTGCATCCCTTCCGTGTAACCTGACACTTTATTCAAGAATCCCGCATTTAGGAGGATCAGCAATTTTTCTGTTACTTAATTTTCCACACGGTAGGAATCGGAGACAAAAAGAAAACGTCATAGTTAAAAAATTTATGCGTTTAATTTTCAGTTGCTGAAAACTCAATTTTGTGGAACCGTGTTTTTCGATCTTTGTAAAACTGAATTTTTTTGAGGAAAATTTGGATTTTTGCTGGAAAGTCAATTTTTGTGAGAAATGGCGGGAAATTTAAATTTACTGAGAGAAATTTTAGCGGGAAATTAAATTTTTTGTTTGATAGTGAGAAAAATTCAATTATTTTTGTAATTTTTCATAATATCTCAAACTCAAAAAAGTCTGAAATTAACTCGAAAATATTGTCATTTGATATTTTGGCAATTCAAAAATTGCTTAAAGTAAATAACGGAACTCGTTTTTTTTCAAAAAACGAAAGGTATTAGTAACATTTCCGGTAACCAAGGTTACTCTTTCCCCATCAATCTCCCATAAGCATGCCAGAAACAAAAGAGTGAGAGAGAGAGATGCGTGTATGATTATTTGACAGTGCGCAACTGACACACATAAAACAGCTTACATCTTCTCTTTTTATTTCAACTGATTTTTTTACCTCCTTGTGTTCTCCGAGTCTCTCTGATTTATTCAGTTTCTCGATTTTCTTCCAAATTCATTCCCTTATATATTTTAATCTATGCGTAAAGTGGAGGAAGATTTCTTCTACGAATTTTGATCTTTTGCAAATTTCTCGGGTTTTTCAAATTATGGATTTTGAAAAAAAAAATTACTGAAATTTATTTTTTTCATGTCACAAAATGACTGTCTACCCTGAATTTTTCTATGGAATATAAAAAAAATTCTGAATTTTTTTTACTTGTTGATGTGTAAAACAAAAAATTAGAAAAATCAGATTTATCTGACGATTTTTTGAACTTTTTTTTAAAATCAAAATTAACTTCAAACAAGATTTTTTTCGGAATTTTGAAAAAAAATGTTGTTTTTTTGAGATTTTAGTACAACATTTTCGTAAAATCGAATTCATTTTTAATTTTTATTGTGCAAATGTTCTGACTGATTAACTATGAGAAAAATTTAAACAGTGTGAAGTTTGAACCCCCCCCCCCCCCCCCCCATTATTTGGACGGAGATACGAAATGTGAATTCTCAGAGAAGGAGGTGAACACTCTGATTGATGTGCATATTGCTCATTATCCATATTAGTTTGGGGCATATCGCACAGCGAGCATGACATGTACTTTTACCCATTTGCGTAGGCTCCGCCATTTCACGATTTTTTTTTTCCAATTTTTGAACTAGTACAAAAATTTCTGAAATTAATTTCTGCAATCTCACATTCCATTGTATTTGTTGCTTACTTCTATTGTTCCACAAAAGAAATTTTCGAATTTTCGTAATGTGTCTTTCAAATATACCATATCCACGCACATATGTCCCTTTTCCTGAATACTAATTTGGTGTCCAAGAGGAAATTTGTTTTGTCGAGATTACTCAGTTCCATTACGGAATATTTTAGTCTCTGAGAAAAATTCACTTCCTAAGTGTATAAGACTAAGTAAGTAAAACGATACTACAGTGTCAAGAATGGTTTGTTTTTTGTTACAGTCTTTACTATGTAGCTTTTGTTTTGTGTAGTTTTCCAACTTTTTTTTTGCCAAAATGAAGGCTGAGGATAAAAAAAAGTCAAAACACAGATTGGTTGCTGAGGCGGTATTATTGGTTTACTGTAGCATTACGGGGTTACTCTAGTTTGGCCCATGTTTGGTGTCGTTAGTAGTAACAACATTTCGCTCATTTGTTTTTTGATTTGGTAACTTCTGGTGACTAAACTTTTAATGTACCTAAATCTTCTGTAGCATTATTGATTTGTTGTTTTCTTCTTTTTAAGTTAAACATGCTCACATTAAATTGAAATTGAAATGGGTTGAAAATATTATTATCAACTTGAATACCAAAAATTTTGGACGGTATTTCAACAAAATTGATTTCAAGCCTCTTCGACCTTCGACACAACAAACGAATGCTAACTTTCCCAGGATTACCCAAAATAGTTCAACGGAATCCCGTTTTATCAATTTTTAGCACATACTTCTTCATAATCATGATTGTAATGATCGATCCGGTCTTCTATTATTAGATGAGAGAAGGCAAGAATATACATATGTGTCTTTTATATTAAATTAATTATATTTCGACACATTCTGCGCATATCACTACTGTACTAGAATTACATTTTGAGTAAAATGTAACCAGAAGAAACAGTTGTTTGCATTTATTGTAATAAACAGAATAGAACATGATGTTAGGAAAGTTATTAAAACTTGCAAAGTGACACAATTCATACCGATTTCTCTGCAATAGCTACTTAGTTCACTTAGTAGGCAGAGTTTTGATACTGATACGGATTCTTAACGGATTTTTAATTTAAATCACTATTGCTTTAATAACCTTTTAAGATTTTTTTGTTTCAGCGTGCAATTGTACTATTTTTTATTCTCTTTCCCCTAGAATTTTAATAAATAGAAAAATTTTGAATTATTTTACGTTATAATTCAATAGTAAAGAATCACACATCAAGCTGCCCCTATTCAGTTTCACATACTTTGCCTGATAAACATGACTCCATAGTAAAATGGACACTTTCATCTTATACAGACACCCGCCCCCCCTTGCTTCCCGATTAAATCCCAATAGTGTGGCAGCATTGTGTTTCATTGAATTTATTATCATTTGTCATACAGTACATGAAATTACAAAACAGGAGAATTCCTAGGTTAAACTTTTATACAATGAAGAAAAGTCTTCCCTAGAATCAATATTAAATTATCAAATGACTACGGTATTTACGTTTTTCAACGACGGTATTAGTTTTTATACTTACTAGTTATTAGTAGTTAGAACATTACATTTTTAAATGCAAGGTGATGCTGTCAAAATTTTTTTAGGGTAGACGAGAAATTGTCATAGTTTCCAGCACCATCACTGACAAGTCGGCCAAATTTCAAACTTTAATTTTGGAACGTCAGTTGGGCGGCCATAACTCTTTTTTTGAGACGTTTTCGGAAGAAGTTGAAATTTGGTATTTTCAGCATAGCGTTGTATCTTATTTAAAATGAGTATTCACTCCTTTTACCTGCTAGTCGGCAGCCTCGTTTTCTCCTATTTTTCACTAATGAGCACACACCACTATCATCAGTATTTTCACCACCTGTTTTCTAATAATAAACATTCCCCTCACTTTGTTTCCATATCGATGCATTTTATAGAAAATGTTCCCCCTTTCTTTCCAATTAGATTCACCCTCTGATTGCTCTTTCTTGGAGGGAATGTTCCACAATTCCCCATCATCTTATTACATATTTATGCAGATTTTATAGCATTTTAGTGCGCTAGATTTTTCATGGGATATTGCTATGCAATCACGCTCTAACTGGATAAAATTCTCAGTTTATATAATGTTAAACCCTACTGTGTGTAAAATTTACAAACATAGTTGAATACATTGAATAAGTATGAACATTTTTCGAGGGATCTATAGAAAATTGCCGGCTGTTCCTAAATAGGGCCCTTTCACTGGTCACCAAGTTCCTGTTCATGCAATTCAAAAGAAATGTTCAGCCCCTCAATAGTCGCCCGCACCACAAAATTGAAAAGCGATCACATAGTTTACTAGTCGAACGTTTGAATTGAACATATTTGGAGTATTTTAAAGAAATTTCAAGTCCACCAAAACATATGCCAAGGGCCACAAAAATTTCAATTTTCCGCCAATTTTTTTCTCACGAAAGTTGAATTTTCTCGAATTTCCGATAATATTCGATTTATTTGAAAGTTATTGAAGTTTATATTTTCTAAAACCACTTCCACAATAACAAATATTAATAGATATAATCCAAAATTTGAAATTCCCATGCAACACCTCAAAAAGTGGCTCGCTTAACTGAGTGCTGTCGCGGAGCACTACCCTTGCATTCTTTTCCCAACGGAGTCATGAACATACGAGCATTAAATGAGTAGACGACATGTGTATACATAGGACCCCCCACCACATGTTCCTTTTATGAGTAGACATGTCATACACACAATGTCTCTCCTTTCCGATTGGAAAATTAAAATCATATAGGAGCGGGGGGGGGGGGGTCTTGACATTTCAATTATTACCCCCCCCCCCCCCCCACATCCGTTACGTTGCATTTTGGTAGGCTTGGGGCCGAATAAGTCTCCCATGCAGGCGTCAAAACGTCTGCGGACCTACGCCTGCACGCCGATCGCGACAGCTGTACAGGAACCCGAAAAGTGGAACGCGGCTAAAGAACCATTCGCACTATGCGGTGTAAACACAAGGTTTTGATTTGTAGTCATAGTGCGTATATGATGCGGGACGCTGACAGGTAGGAGGCAAGCGTTCAACCGCGAATGCACACCATGGAAGCGCTAGAGCCTAGTTTTAGATGAGTTTCAGCATTTTTGATCTACAAGATTTTGAAAGTTTTACAAAAAGACCAAGATTTTTTGTAATTTATGAAGAGATTTTTCTACATTTCATAAACCAGCAGAGTTGTTTTTTTGGTAATTTATCATTAGCGCGTTCGCGTCATGAAAACAAAATGGCGGCCGAACTTTGACAGATGGCTGAATTTTTCGAATCGAACAAAAGTCCGTAGCTATAAAGCACAGGCCTACCTTGGTTTTTATTTGCTTTTAAATGATATAGTTTTCTAAAAAAAAGTCTATGGCCGAATTTTTAAATTATGAATAGGGGCTATTTCAAAAAAAATTTGAGGCCAACCTACTCTACTCAATTATAACTTGCCATGGCAGAACTTTTGAACAACTATTACAACGTTTTCAAAAAATTGCAAGTTAATTTTTTCGAATAAAGGTTAAATGTAGCCTAGTTTCTCAAAACAATAAGTGAATAAATATCGATGACCGAAGTTTATATTTGATAAAATAGTATTTGACCTAGAACTTTTAACTATTCTTCCAATGTCTGAAGTCTGGCTTCTGAGAAAAAGTTCGTGGCCTAAGTGTACCACGATGGTCTAGTTATCTCGATAGCCATAGCCTAGTTTTCTCAAAAAAATCTGGTGGGTTCCTGTATGTAGGCTTGTAGGTATTTAATTCTTATCTTCCAGGTATCTATTTCTACTTGTAACCAGGAGCAATAGTTTTGAATTCCCTCTCCCTATTCACGCTTCTCCCCTCACACTCGTTTTTGGTATTCTAATGTTCTCACGAAACTCCTCTTCCCAATCTACCCCCATTTCTTTTCCTCTTGGAGACCTGTCTCTCTCTCTTTGTATTGCTCTTTTACGTCTTCGAGTAGGCTTTTCCTTAAGGAACTTGTGTGTGTCTTGAATCATCATCGCGTTTACGCTCTCGTTCCAATTCCCTGTTGCTATTTTCTTGGAGACATTTGGAAAGTTTCAAAATTCCTACGTACACCTGCGAGGCCTCAAAATCTGGTTGTATATGGCATGACATTGAATTTCTAGTGCACACAATAGAATTTTCCGGGAAATTCAAATTTCGCGATCTGATAATGACTGAGGAAAGACTTTGGCGGAAATTCAAATTTTAAAAAAGTAGGCGGGAAATTCGAATTTCGAATTTTCTAACCTTTTTGGCCTTGGTTTCAAATGTTCTGAAAAATAATTTTGGAGCGAAATTCATATTTTCTCAGAAATATCTCAGAAAATTTGAAGTTTCTCCCACTAATATTCTTCTCAAAAAACAGTTACGTGACCTATTTATGTCCTATTTATTGGTCCATTTATTACGTGGCCTAGCGAAAAACATTTTTTCCCCTGCGATCATTTGAGATGGCGTAGAAAACGCAGATCCGTTAGGCCATCAGGTTTACGGGTTATAGTACAGCCTCTTGCAGGGGACAGGTTCAGAAAAACTACAAATTTAGTTAATTCCCTACCTACTCTTGCAAATCAATAACTAACCCAACTGTGTTTCAATCCGGGGAAATTTATTCTTAGAAAAAGTATATCTCCGCAAGTACATATCCCTCCTTCAAAATAATAATAATGGGAGGCTTCTGCTTCTCTTTTTTTAGACCAAAAACTTGTTGCACAGTGCCCTAATATGTACGGTCGTTGAGTTTTGTTGTTCAATAATATGTTGACCGTAATTCGCGCATCTGAAGAGGGGAGGTGTAAATGCTGTGTCTAAATGTTGCTGTCACCTCCAAGTGGTACAGGTGGCCTAATTTGGGAAAACTCTTCCACGACTATATTTCTCAAAAAATTACTCATAAAATTTGATTTTCTCACATATTTCTCAGAAATATTTGAATTCCCAAAATTGTTTAAAAAAATAGAATATCTTGTCAAAATTTTTATCAGATTTGAGTTCCACTAAAATTTTGCCGAGCGATTTTGTTTTCCAACTTAAAAGAGTTTTTTTTTAATTTGACAGTGAAAAGTTATCTCGGTCAGTATGCTTATACATTACAGGTGGCCTAGGTCGCATTATACAAGCCACAAATCTCCCAAAGGGGTATTGCCACACCTAATTGACACCTCCCCGGGGACCTTTGAGCACTAAGTATGGACACCCACCCCTCACCTATCAGCTTAATAGCTGCCTTTGACCGCTAAGGAGCATACCAGCCATATGTTTACTTAATTCTCTCACTCTCTCTCTCGGCTTCTAAATTGAATCTCCCCCAGTCACGCCTCTCGTTACGTGAGGAGTGTTCAACATGTTCCATTCCCTTCTCCGATAATCCGTGTTTTTGGTAGGCAGGAGCGTGTACTAGTAGAGGACATTTGTCGCTTCTTGGCCTTTCGCCTCCATTTTCCTTAATTTGTGACTTAGAAAATCGTAGAAAAAAGCATTAGTTTGTAGGACAACTTTTTATACCTCTGAAAAAAATGAAACTCGGCCACCGACTTTGTCTGTCACTTTTGTGTAGATATGATCACATGCTAAACTGTCGAACCGATGAGGTCAGGGTGGCTGAGTTTGCACTTTTGCGTGTTCTATACCATTTACAGAAGCTAGTCCCCCCGTCATTCTTCTTCCAGCAAAATGTTTTTTTTTGCCTCAATAGCGGTGTCTCATCAACAGCACAGCAGCCAGTTCATATTATTTGTTTTTTGTTTCGTCTTTCGTCTTTTCGGAAACGCTCTATTCTATGACAAGGTGACGTCATTGGACTCGTGGCCTAGAAAGTTTGGCAAACTCTTCCACCATTCGATTACAGGAGCCTCAAAGCCCCACATGGCTAAATCTTGACATTAGAAACATCCATTTTGAAATTTTTCGAAATTGGTGCAACCTAGCGACCTCTAGAACTTCTGACCTAGAAGAAAAAAAACCTCAAAATGTGGACTAGAAACTTTTAAAAACTCTTCCATCGATTTTGTTTTGTGGCGGCGGACGTTTTCCAGTTTGGCTTTTCACATAAAAACCAAAAAAAAACAAGACGTAAAGCTGTGAAAATGATTAGTCACAAAAAGAAGAAAAAAGTGTCGTTACTGCAATTTCATAGATTCCTTCTTGGCTTCTCACGACACGAGGGGGGTAGGGTCTAATTGGCACCCCCCCCCCTACTGAGGTGAGAGAGCAAGCTTGAGACTCACCCGTCGCTCTTGTTTTATGCATTTTTGGCACAAAGTGAAGTGGGCGAAAATTGTAGTAGCTGTGTGTGTGATGTGTGTATGAGCATTTCGATTTTTAAAATAGTTTTTTAATGTACCGCAGGCCACGTGGGTTAAAGTTTTTTTTCATAAAAATAGGATTTGTTTTCTTGCAGATAAGTTTTTCGAATTTTGAAATGAAAAGGATAACTGGGAACTCGGAGAAAAATTATGTTTTAATTTCCAACTAGGCCACGTACCAATGACGATGAGCAGTCGTTCTAGATCACAAGGTCATCTAAACTTTTAGGAAATTTAAAAAGTTGGTGATTACTAGAATTTCTAAGCCACGCCGCATACACCGGCGCGTAGGCGTTTTTACACTTTCTAGACTACTAAGATTTTCCTAGGCCACGTCCAAATCAGGGCTGTTGCAAAAAAAAATTTTCGACCAAAAAACAAAAAACAAAAAATTTTTTGGTGATCTAACTTAAGAATAAAAAACAAAACACAAAAAAACAAAAAACAATCGCAAAAAAAATTCAATGTTTGATATTGAACGGGACAAAACGGAATTTTTTCGTGAAATATTCTGGTGAATTTTTAATATTGAAAAATTGAACGAACAGAAGGTTTCTTGTTAGCTTTTTTGCTGAATCAATTACGTAATCTATTTTTTGGTTGTTTTTGGTTTTTTTTTCTCAAAACCAGCGATAAAAAACCAATCAAATCAATTTTTCCCAAACATACCAAAAAAAACCAAAAAAAAATGCCCAGCCCTGGGTCCCAATGTACAGGTGTTGTGGTGTGTGAGCTCTTAGGCCAGCTGGACTTTTCTTGGCCACTTGTAAATCAATAGCTTTTTTTCGGTGTTCTAGGCCACCTGTCACGCCTAGACCATTGACCTAGTAATGTTGAATAATAAGTCCAAGTACTCACATACCCGCAAATGCACATATCTATCTTCATTTCGTGATCTTATCTCTTCATCTCATCTTATTTTCCATTTCGGTTTACCCTTTTTTTCTCTATGAATATATTTTTCATGTACTCGCTCTTCATTCCCTCTTTGAAAAGCAAGATTCTTTTACACTTATTTTTCCTTAGGCAGTTGTAAAGAACTTGTCATTAGAACTTTCAACATCAGAGTACGATGGCCGAATTTTTTCTAGGCCCACGGCTTGGGAGCCAAACATGGCTAAACATTCACTAACTTCCTAGGTCATCTAGAAGTTTCTAGGTCTTATGGGTGAAAATTGGCAAATGACAGAATTTTCTTAAGTAATAGTTGAATTTCCCGCCAAACCGATTTTTTTTTGATAACATTTAAATTTCCCGCCAAAAATTTTTTGAAACTAAATTTTATGCCACACTTTTTCTGAGAGAATTTGGTTTCGCTCCCAATTTTTCTCTGAAAAGTTTAAATTCGCACCTGTGTAAATTTTTCGAGAGCTTTTTGAAGTTCCCGGCAAAATTTCGAAAAATTAGACCAACCTCCCCGACCGTCAACTATGATAGAGAAGTGTCCTCTGTACCCTGGCCGAATTTTCAATATATTTCTAGACCCGCCACATATTGCCAGCTAAATTATGTTGTGGAAGAGTAGTGACGTCACTTGGCGACCGCGACCATCGAGGAGCGTGAGGGGAGATGTATCCCGGCCTTCCCAACCCTAAAGACCTCGCTTATCGCTCCTTTTTGTTGTATCCGTTTTTTGGTGTCTCGATTCGTTTTCTCCTGTTTGTTGTCATTTCTGAACTCATCTCTACACTTCTCTCGTCTTCTCTGCGTCTCTCCATCCTGCACACTATTTTTTACCTCGATGATCTTTCTTATTGCGTGTGTGTCACTGACGAACGAAAGGCTGACACAGACTATGTATTGTTTGTTTTGTTGTTTAGAAGTAGTTGTAGTATTCCAATCGTTTTTCACACTACTTTGCATTATTTCAGATGGCTCAGGACGGGCCATCACATTTTTGTCAGGCTCCGCCGCCGCCGCCACCTTCCTCGTGGATTCCAGCTCCATCGCAGGTAAATTTAAGGTTGCAAGCGCGCTATAATGACCTTTTTTGTGCCTACGCCTCCTGGGTTATTGCCAATGCCCCCCAATTCGAATTATTTTTACTTTCAGCCAAATAGAAAAGGAGCCGCTCATCGATGAGGAAACTGTTATTTACGAATCCCGAGCCACGTATTGGAAGGGATGTGAATGAAGGCCTCTGGCTCGTACGACTCGAGTAAATGTAGTGAGTTGGTCTAGAAAATTTGGTAAAGCTTCCACGAAGTAATTAATTAGGGATATTACTGCCGACACCCAGGAACACGTATACCACGGCAAATTTTAATTTTTTGAAAATATTTTGGCGGGAATTTAAAATTTTAATATGAAGATATTGATTGGCGGGAATTTAAAATTTAAATTTTTTGAGAATATTTTGGCGGGAATTTAAAATTTTAATTTTTTGATAATATTTTGGCGGGAAATTTTATGAAATTTTTTGAAAATTTTGGCGGGAATTTAAAAATTTTTTGAAAATATTTTGACGGGAATTTAAAATTTTTATTTTCAAATTGGCGGGAATTCAAATTTTAATTTTTTTAAAATATTTTTGCGGGAATTCAAATTTTAATTTTGAAGCTTGAAAATATTGGCGGGAATTTAAAATTTTAATAATTTCTGAAGGTAATATTTTGGCGGGAATTTAAAATTTTCATTTTTTGAATATATTTTGGCGGGAATTTACAACAAATTTTAAGATACTTTTTTGAAAAGATTTTGGCGGGAATTGAAAATTTTATTTTTTTGAAAATATTGCGGCGGGAATTTAAAATTATAATTTTAAAATATTTTGGGAATCTAAAATTTTAATATTTTGAATATATTTGGCGGGAATTCAAATTGTAATGTTTTGAAAATGAATTATTTTGGCGGGAATTTAAAATTTGATGTTAATTTTTTGAACGGAATATTTAGGCGGGAATTTAAAATGGCTTTTAATTGTTTTGATGAAATTATTTTGGCAGGAATATAAAATCTTAATTTTTTGAAAATATTTTGGCGGGAATTTTAAATTTTAATTTTTTGAAAATATTTTGGCGGGAATTCAAATTTTAAGTTTTTGAAAATATTTTGGCGGGAATTTAAAATTTTAATTTTCTGAAAATATTTTGGCGGGAATTCAAATTTAGATTATTTTTTCTGTTTCTAAATATTTTGGCCGGAATTTAAAATTTTAATTTTTCTGAAAATCATTTTGGCTGGAATTTAAAATTTCTGAGAAAAACCTTCGTGTCGAGGCACTCGGTGAGACCCTTCGTGGTGAGACCCATCGGTGACATCCATCGGAAGGTGGTGAAAATAGACCTTCGTAGTGAGACCCTTCGTGGTGAGACCTTTCGTGGTGAGAGGCTACCCATCGTGGTGAGACCCATCGTGGTGAGACTCATCGTGGTGAGACCCTTCGTGGTGATACCATCGTGGTGAGACCTTTCGTAGTGAGACCCACTACGGTGGTGAGACCCATCGTGATGAGACATCGTGGTGAGACCTTCGTGGTGAGACCCATGTGAGACCTTTCCTGGTAAGACAGGTTTTCGTGGTGAGACCCTGCATCGTGGTGAGACCTTTCGTGGTGAGACCTTTCGTGGAGAGACGTTTCGTGGTGACGTAGGACCCATCGTGGTGACACCCTTCGTGGTGAGATCCCCATCGTGGTGATACCTTTCGGCGTGGTGAGACCCATCGTGGTGAGACCCTTCGTGGTCAGACCCATCGTGGTGAGCAGACCCATCGTGGTGAGACTCCCTTCATGGTCAGACCCATCGTGGTGAGACCCTTCGTGCTGAGACCATTCATGGAGAGACGCAGCGTTGTGAGACCCTTCGTGGTTAGACCCATCGTCGTGAGCTTTCGTGGTGAGACCCATCGTGGTAAGACTCATCGTTGGAAACCCTTCGTGGGGAGACTCTTCGTGGTGAGACCCTTCGTGGTTAGACCCATCGTGGTTAGACGCATCGTGGTGAGATCTTTCGTGGTGAGGATTCCCCATCGTGGTGAGACCCATCGTGGTGAGATTTGGTGAGACCCATCGTGGTGAGACTTTTCGTGGTGAGACCCATCGTGGTGAGACTTCTTTCGCGGTGAGACCTCCCTTCGTGGGGGACTCGTCGTGTTTGATATTAGGCGAGGAGCTATGGAGCTGGAGTGGGATAATGTCAAGGTACTATAGGCGTCTTGTGGATTGGCTGTAGGGTTACTGTCAGTTCAGAAAAATTGACTTTGTGCTTTTGAAGAGGTATTGGCTCGAGAGTTAGAGACGCGGAAGCTTCTGTGTTTTTTACATTCAATGTTTGAAAAAGTAATTTCCAACAGTTTTCATGTGACTTGAAAGATTAAGATATGCGGTGTTTTAGGTGTCGAACAATTGAGATTTCGGCAGTCGTTGGCCGCGCCGTGGGCGCGGTCAGCGGCTGGTTTTTCCAGAAGAGGAATAAGAAATTTTTGTGGAAGTTACTAGGACCCTGAATAGAATTCTAGGCCATGTCGAAAAAGGGGCTGGGTGCACGTGGGAACCTTCGAGTGTTTGGATATTTTGGTAAGAAGTAAGAAGAAGGAAGGTCATAAGAAGTTGTTAAGAAATTGACTTTTCTAGAGTAAGAATGACTTTTCTAGAGATCATCTCCCCCTATTATTCACAGCGTCACCTAGTTATCCGGAAAACTCTTCCACCAAAAAATGTGCTCGCGAGTCCAACTGAAAAATGCGTCATAAAACACACGGAAAAGGTACTTGTGTATTACATGCCCTCATTTTAATAGTAGTTTTTTATGAAATAAAAACGTGAACCATAATTTGAATTTTTAGGCTTAGGAAATAACATTTTCTAAGCCTAAAGAGGAAAATGTGTAATACACAAGTACCACGGATAATTTTTTGAAATCTTCCGAATTTGAAATAATTTAACTAAAACTTTCTAGGCCACGATGAAAATAGAAACAATGTGTCCCGATTATGCTGAAAATTTCTGAGCTTCCATAGTTATATCGAGTAAAAAGATTTTCGAGAAATGAGTTTCTAGGCCACCAGAAAAGTTTCTAGGCCATGATCCCTTCTTGATCTCGTTTATCATTAGGATTATGATATTTTTTCAACGATTTTTTAGGCCACCAGGCGCAAGGGAAAGTCCGTGTCAAAAAAAAAAGAAAGGGGGTATTCTGCGTTTCCTCGTCACGTAAAAATCCCGTTGGCCTTTTCAATCAAATTTCTTCAATTTTTCGCATAAAACTTACCTCCGGCTGTGACAAGCCTCCTCCCGTCTCCCAGTATTCTCAATTAATCATCACCCCCAATGCCCTCATCCAACTACAGTATCCCTGCAATCCCCGTCTGCAAATATGTGCCGAATATGTCATACTTCTACGTCAAGACTACGCAGTCAAATCCGCTCATCTAATCACCGTGTCGATGCTCTTGGGAACACTGCTCTGTGTGCATCGTGTGTTGTGGTGAGCTCTTTCTTTGTAAAATTCAAAATAATAATTAAAACTTAAAAAAGAACGTGACTGGAATTTGCAATATAAAATCGTGGCTCTATACAAAAATTCAAGTTATACTTCCACATTGTCGTTCCAAAATAAAAAGAAATAGCCAAGCCTACAAAATGGGCGGCGCTTTCATAGCCACGTCCATTTTGTGGGCGGAGCATCAAACTTTTTTCAAAACCCTACTATAAGTTGAACACGGATTTCTGGCTTCCTCATCATAAATCGACAATGGCTGAGTTTGACGAACTAGGCCATTTTGGGTCGGAGACATTTTGTGTAGATTTACGGCGTGTTGCGTGTCGCGTCGCTCGTTTTTAGTTGTAACACTGCTTGTGCCGTGTACATGATTCCAGGTTTTCTCCACGCGCTGTCCCACGCGTTGTCAATGAGGAGCGTAAATTCAATGCGAACAGAAGCCCGTGGTTGAAGTTTGTTTTCAATACTACAGAAGATTTTAAAGAGGAACAAACAGCTCATGTTGCCTGGCTACAAAATGGGCGGAGCGTTGGAGGCGTGGTCTAAGAAGGTGGTCATCGCCCTTTTCTTTAAATACTTGTTCTGATGTACAATAGAGCGCATTTACATCAAATTAATAATTAGTTTTTTAATTTTTCCAGATGGCTGGAAACATATGTCGACTCGAAAAATGGGCCCATCACCACGTTGCGAACTATTCGCGGCTACGATTATCGACGTGAAATTCGGCATACTTCAAATGAAAACATTACATGTTCCACACGTGGATCGATCATCTTGTCTGCACAATTTATGGTGCTTTTGATCAATCGTATTAATTATGATATTTTGGTATTTTACGATTCGATTCATTCAGGAGAATCCTAGTTAGTCCGCTCTTAAAACGAAGGTGGGCGAAGTTTTCTGGTGATGACCTAGGAAATTGGAAAACTAGTGCCACCCTCGCAAATGTGGCTAAAATAAATTTGACTAATGGCCTGCGGCCTAGAAAAATAAAAGTAGACAGTATATAATAAAGTCTCATCAACCCTTTTGGAGAATGAACTGGAAACCCAAATTTTTAAGAAAATATTGACCTCCTTTAAAACGGTGGCCTACTTTTTCTGATGGCCCTAGGTTTTTCGACCAAGAAGCCACACAGCTCCATAGTTTCAGGAAAAAAAATAAAATAGGCTCCGCCCACATCTTCTTGCACGTTGAGTTAGAATATATACGAGCCATTTTTGCTAAGTTTTGAATGTTAGCTCCGCCCACATAATGATTTGAATTTCCCGCCCATTTTTCTCTCAAAAATATGAAGTGCCTGCCAAATTTTGCGAAAAACTCAATACTTTCAGGCTCTTCGCGCACGACAAACAGCGTACACGTGGAAACGGCTTGGCTAGTTCAGCGGAAGCGGGAATGGAGACGGGCGGTAGTTCGGACGGATATTTCTCGCGTACACCTGTCTCATCACTTTTCGACATAAAAGTGGTCTTGTGTGCCAGCATGTTCTTGGTCTCGTTCATTTTGGCCCTTCATCAGTATAAGTGAGGGCTTTTTTGACACGTGCCCTGGAAAATGATAAAACTCGGCCACCTATTTTTTCAGCCGAATTTTTTTAGTTTTTAGCGGTCACACGGGCTTCTCATTCTCTCTGCATTGCAGTTTCGCGCTCCATTGGCACTGGCTTGCCGGACAACGTAGGAAACTCGTGTACTCCACACGATAAAATTGTTCAGTTTTACATTGAAAACCGAGCCGTGACAAAGGTCGCCGTAACTGTACCCCGGCCGTGGCCGGTGAGTCAAAATGGCATAGTTCGGCAAATTCTTGAATTTCAAAATATGATGGAAGCCTGATAGAGCACGTGCGGTGATAAAAATGAATAAAGTATCCTGTTTTTTTTTCCAGAGGCGAGTCCACGATATTCCGATGTATTTTCCGATTCGCTTTTGTGAGCTCAATAAGTATCGGCGCGATGATCAAAAAGATATCAAGTTCTGAGTGGGCGGAGTGTATCGGCGGGAAATTCAGGCAACTTTGATCTTTCAAAATTTTCATAAAAAATTCGCGCAAAGATCAAAAACTCAAAACTTTCGGTTAATTTCGGCGCGAGATTCAAAATGTTTTTGGGAAATTTGGGAAAATCTAAAAAACGTTTAGGCGTTTGAAATTTTTTTAATTTTCAGAAATGATCCTGGAATGGCTAATCGCCGCGGTCTCCTGAAGTCTTCATATCACCCGTTAACCGTACTTCTGATATGTGTATCCGCGTGGCATCCTAGTCATCTACGAAATAAACCATTCGCTCAGTTACAATTTCTCATTTCTTTACCACTTTCGGGTTTTTTGCAAATTAAAAAAATTTCGATATTTTTTTTGAAATTTTAATTTTCCAATATTTTTATTCCACAACTCAGGTTGCTCAACTGTGCCTAAAATAATTTTTATTTCTTTGATTTTTTATAAATTTAATACAATAAAAAAATAATATTACACATTCGTGAAACACGGAAAAAAAATTCAGCCTATTTACATTAAAACACGTGGAATTTGAAATTTTAGCGATATATCGATTACCCCTTCTCGGAAAACTCGTAATAAATGTGAAAAAGGCGAGGAAATTGGAAGAATTAAATGCGGGTGTGGGTTTCTAGAAAAAAAAAAGAAAGTAATTAAAGAAAAATTCAAAATAATGCTCCGGTGTCATCGTGTTCCACAGTGGTTAGATTCTGGTATTTTGTGCTGATGGTGTGCTCTGAAATTTAAGAAAAAAGTAAAAAATTGAAAAAAAATTTCTTAAAATAAAAAAAATGAACTTGTTTTTAAAATTTAGATTCAAAAATAACAGTTGATATATTATTCATACATATGTTATCAATTTTAGAGAAACTTCAATTTTTCAACTGACTAACGTATACAAATCTACTCGAAAAAGACCTCGGAACTAGTTTCTCACTTGGTGGCCTAAAAATCGCCACTAAAACCATCGACCAATATGAGTTTGTAGGCCTCCATATGAAAAAAAAACTCGATCGGGGACTAGGTTTCCACATGTGGCCGATTATCAACTTCAAATGTTTTGGTTACCTAGATTTGTCAGAACTTGGATTACTAGTCCACTAAAAGATTTTCGGTGGCCTAGAAACCAAATTTGCGTGAATTTTTCATAATTCTATATCAATTGACTAAACCGAAAATAATGCGATGCTTATATTTCATCAGTTGGTGACACTATCCCACGTGGCGACGGGATTACGGGCGACCGTGCCATTGATTAGAGCCAAGGGAATTTTGAGCATACTCGTCGGCGGTGCACTTGGCGCAAAAATTTTTTCTCTTCCGTTAAAGACGCATGGTGGGTCTTGATCTAAGAAATTTCGTGATTATTCGAAAATTTTTTCCTTGTCCTTATTGACAATTTGTGTTTTCACAAAAAAGGCGGAAGTCCTAATTGCCAAAAATGTAGGTTTCTAAACTAGGCCACGAAAAATAATTCAGTTTTTTGCTTCAAACATCCTGCTTTTTGTCCAAATTTCGCTTTAAATTGGAAGTGGTGTCCGAACATTATTAACAAAAGTTCAATTTCTAGAGAACATCACTTTGTTCTAATGGGTATTTCCTCACATTTGGATTTCTAGCCCACAAATAACGTTTTTATTTCATATTTTTATAAAAATCGAATTAAAAGTAGATGATGACCTAGTTTTTATCAATAATTTGGGTTTCTCGGCCACCAACTTTTTAAACATTTTCTTAATTTTCCATAACCAAAAAAAAAAAACAAAATCGATGGCCTAACTTATTGCGCTTCCTAGGCCACCAATAACTCTTTTATTACTGATTTACCTCACTCTATGATGTCGATATTTCTAGTCTCGACTATCGCTTCCCACAGCCATCACACTCAAATGCTCCATTCGTCTCATGAGTGAGCGAGTGTTGATTGAGCCCATGCTTCGGAAAGTTTTCTCGCAGTCCGTTATAAGGTTGGTTCCATTGTTGGGCTGGGGTGAGCCGACGACGGGGCCGCCCGTATTGTCGCCCTTTTCCCGGTTTTTTCCGGTGAAAAAGTGTCGAAATAAACGCGTTATTGTCGTCTAATTTTGGTACATTCGCCGACATTGCGAGATTCTCCTGAGCCACTGTGACGTGTAATGTGATGGTGCTGATAGAGGTCTGGTGGTGGCTGAAAATGGGGAATATTCCCGGCCCCGAACATTTTCAGAAGTTCCAGGTCGAATCGTTGTTGAGCATCCGCGTCGACTACTTGATTGAGGGAGACGGTTCAGTTCAGGAGACTGGTGGATGGCAGTTTTATAGACATAAATCCTGCAAAAACTCAGGTTTGTTGCTAAATTTTTCAATTTATCATTCTCATTTCCGAAAAATTATAGCTTAATTTTAATAGATTTTTCGCTTGATTCTCAATTTCTCGAATAGTTTTGTGTCAATTTTTTTTTGTTTTAAATGTAAAACTACGGTATTCAAAGGGAGGAACACTAATTTATCCCGATGGGGCTCGCGGCGAAAACATTAAGTGCCTTAATTAAGCCTTGCGCCTGGAAGGTAACTGTAATTTTTATTGATTTGATCGATTCATTTCATTCAATTTGTGGTTTTTGAAGGTTTTCAACCCATTTTGAAAGCTGAAATTTTAGATTTTTATTTCTGACAAAAAAATTTTAAATGTTAAAATAATTTTTTTTCTTTTTCACACAAAAATTGTAACCGAAAATTCCGAAAAAATGCAATTTAAACAGCTCTAAAATATGAAAATTAACGCGATTTTTATCATTTTTTGCTTCAACTGACTTCTGGCAAAAAAAGGAAAATTCAGCAAAAATCAATTTTCCAGAAAAATTTGATTGATTTTTAATTTTTCTTAATCCGTCGTCCGTACCGTATGTAGCTTCATCTAACACCTTATCCAGCAGATTGCTTACATCTAATTGCACGTGGTTGCAGTTCTGAAAAAAAAATGTTTTTGAGTTTTAGAAAACTTATTTTGTAAATGTTCTAGGTGGGTTTTAATTGTATAATTAAATCAAATTCTTATTCAGTTTCTCCCATAAATCGCTCCAATTCCGCTTCTGATTTTCCTGAACTTTCTCCACTTGCCATCACGGCCAAATCCTGCTGCTCACGCAAAAATTATTTGACAAGACACGTTAGCTGGTTTACATTATAGATTGCTGGCATTTTTATAATCTGAAATTTGAAATTAAGGATTTTAGTTATTTCCGCAAAACGTAAACTTTTATCGCTGGGAAAACTCACATTTTTCGAACTTCGCCCCAATAATCGTCTAGTGAATTCTTGAATAAACCGTTTGCTTTCTTGACATAAAATTCTGAAATACCTCATTTCCCATGAATTCGCCCATTTTCCCATGGAAGAAAACCAATGGAAACACGGAAATATTTGCGCACAAAATCGATGCTGAAGTGTCGTCGGACCCAGTGTTTCGTGTGCAGTACACGCCTACGACAAATTGCGGACTTTTTTGTTATTGGAGAGAGTAGAATAGAGAAGAAAAAAGAAGATAAAATGGATAAAAATTGCGCGTTTTTCTCATTGTTTTTTCTCTGAATCTCTCAATTTTTAGGTTTTCGGTCCATATACGTCCCGAGTGGAGATGAAGCGATAAATTTTTCGCTAAAAGTTTCTTGCCCCTCCAAGTCGCTTATTCTTTTTTAATATGAAAAAAAAATGCTAAGATGCTTATCAAACCGCAAATTTTTTATTGGAAAGTCCCCAATATTTTGCAATTTATTGCTCAGTTTAAATTCAAGGTGCCATTCTGCAAAATTGCATTCATCTTCATATGTTACATTTTTTAAGTAAAAACTTGAAAACTCTGCTTTACATAATAGTACTGGAATTTTTCAATTTTCAACATTCAGGATAATCTTTGACCATTTTTTATTGAAATTTTCAATAAAATATTTAAAAGATGTGGCTTTCCAAGCAGATTTTCCAATTTTTCCGAGTTGAGTAACTAAGTTTCAACCAAAATGATGTCACAAGTCAGAAAATTTCCCTAAATTAAACAAATGGTGAAGAACTTGATATAGGATTAGAACAAAGATTGAGTCTTGAGATAATTTCGGACATTTTCGGAAAATATACGTTTCCTGTAGTTTCAAATAGGCAATTTGACTTAAGGTTGCTAATAACATTAAGAAAAATCTATAGTCTCCACCCAATTCAGATTGGTTTTGTAGATATTTTCAAAATATCGTGTAACGAAACTACAGTAATGCCCACTTTGAAATTAAACTTAATCCTGTATTGCTTTTGTCCATCTACGGGCTCGATTTACGAAATTAAATTTAATAATCTTTAATCTATAGAATATTAAAATTAAGCTCTAAAAAATGAGAATATAATTACGTAGAAATGAAAAATGGAATCTCGGTGTAAATATCCGAAATAAATTCATTTAGAAAATCGAGCCCGTAAATCGACGTTACGAAGAATTACTGTAGTTATCGCTACGAGATATTTTGCGCGTCAAATATGTTGAGCAATACGCATTTTAAGAATTTACTGTTATCGTAATAGTTCAATTTCGAGATAATAATTCCAAAAACAATTGTGAATTTAAGGTTTTTTCCGTAATCTAAAATTGATTATCACTACACTGGACACTGTTCAAACTTAACCATTCAGAACTTGTATAATCCATCTCGGATAAATTGTTGGTGAGACAAAGTGTAATCTGTTCTAGTTGGGTCACACGATCCCTTTTCCACTCACATCGCTTACCCACTCAACACTATAGACGATACACTCACACAGGAAATAGTATTGTTTACCTGTTTTCTTCTGGACACTGTTTATAACTTTTCCCTGTATCTCCGTTTCTCTACCTTTAAATTTATCCAAAATTAATAATTTTTTAACTCCACATTCAATACTCATTTAATGACCGGTATTTGCAGAAAATATTTTATTTTTATTTAGTTATTACAGGAACAGTATACTCTAGGAATTCGTATTGCACAACAGATTTGACGCGTATCACGTTAGCTGGCATAATATTAGGCATTGTCTCTACAATCTTGTAATGTATAACTGACTCTTTGAAATAAGTTTGTAAAAATTGTGAGTAGGAAAACATTGTGCATGGATGTCGCGTTTCGCGCACGCGCTAGAGTAGTCATAAACCGCAAGATTACTGTTGTTCTCGCTACGAGATATTTTGCGTTCGGCGTCAAATATGTTGTGCAGACATTTATGCATTCCTCAGAATTTTGTGTTCACGTACTAATAAATTAACTTGTTAAAAGATATAATAAAAAGTGTTAAAAGATACAGAGATCTTTTCTCCCTTCCCTAATATGTTTAACTGCATATTCAATCATCTTAAATTGTGCCGAAAATTTTTCGTTGTCCAATTGTTCGGAATTTTTTCGGTTTTGCTCGAAAAAACCAAAAAGCAAAATTTTATAAATTTCCCTGGTGTTCAAAATTTTCCCGCAATTTTTACCGATTTTATTTGCAAAATATTTTTATTTATTTGAGTTCCCCCATGTCACACCGTTCGATGTTGGAGAAATGGAGATAATTCCGCTGCATTACGGAGCACGTTGGGATTTAGGACTTGACGTCTTGGCGAAAGGTTGGTAGATTTTAATTTGTTTTTTAAATCCTGGCCTTGCACATTCTAGCAGGGAGACGTCACTCTGAACATTGTTCAACATATGTAAATTTTAAATTCAAACTACTTAAAACCCGGAAATCACTTTGTGTCAGATACACAGAAATAAACAAGTTTTACCTTTTAAAAAACTTAAAACCATTGAATTTTTCACAAATGTTCTTTGAGACTTGAGATAATCTAAATCCCAAACTTTTGGAAAAAAACTGAACATAGGTAGCCTAGAAAATGAAAATTTTCAATAGTTGTGTTTTTCAAGTTCAAAGAAAAAAAATTGAATTTTTAAATCGTTCTTTTTTTGGCTACAAGTCAATAATGATATTATATTTAGTTTTTAAGAACATTACTAAAATGAGTGCATATTTAAAAAAAGTGTTTGTTTCGGCGAAAACAACTATTAGTAATTCCGTGCACTGCAATCATCAGATTAGTGAGGAATTTAGTTCTATTTTTTGCTTGTTTTTCTGTTTCAAAGTCGTTTTTTCATGAAAAATAGACCTTAGCTACAGGTTCTTTTGAGAAATCCCGCATTATTTCAATTTTCAATTTCATGATGAACAACGTTTTTGGTAACACATTTAATTCTAGTAGAATATTATCAACTTTTTCTCTAATTTTTCAAAATTTACACTGTTCCTAATAGTTTTTCTGATCAATGAAGGACTACCATTTTACGACAATATTGCCTTCAATTTTTTCTTCTGAAAATTCGAAATTGATCTGAATCAATGGTGCCGGTTTTCTTATTTCATCCCTGAATAACGAAATTGATTTTTATTTATTTTTCAACAATTCCCGGAAATTTCTCTATAAAACAAATGAAGTGAAAATCGATTTTTTTACTTCGAAAGTTAAACATGAAATTCGATAAATTTAATCTATGATCTTTCAAGCTCCGAGTTTGAGGCGGGATGTTGATAATTAGAGATATGCCGGGGGAGAACACGACTCTCCAATTATATCTTCGGTCGAGAAATAATTTTAAACATCAATACTATACTAGATTCTAAAGAAAACTAATTTTTTTCAATAAATAAGTGTTATTATTATTCAGGAGAATTATTTTGCTTCTTGCTCGAAAGAAAATAAATCCGAATCAAAAACCGACGCATTTACAAGTCCTGAATTTTGTAGTTAGTCAGAGATAGATTTTTATTTAGCCTCAAATTCTAAGAATTCAGACCTGGCTATTTGCCGAGCCTAGAAAATAGAACAACTAGGCCACCGATCGAAGATTTTGTGTTTTGCCGTTGTCAGGCTACTGGCCTAACTTTCTCTATCTTAAAAGATTCCCAAAGTCAAACTACTGGCTTTCCAAAACCTTAATGTAATGAACTTGTGATTCCAAAGATCTGATGTCAAGAATGTCCATAGTTCATATATACTCCAACGACACTTTTGGAATTTATTTTAAATCTTCATGGTTTTCAAAAAGAATCCACCAAATTATTAAGCAACGGGGTTTTCCTTTCTAAACAATTGTGTGACACAAATCAAGGAATTCTCCGTCACTTTGTACAATTTTTCTAGTTTTGGTGATTTCCCCTGATGAGCTCAACGCCAGGCGGAATAGCTCTTTCCATGCAGGCGTTAAAACGCCTGCCTGCCTGACTTTAAGGCGGCCTCCGCCTGCCTAACGCTTTAGTCCTAGTCATGTGCTAAACCATACATGAACTATTTTTCTAATTCTTAGTGTCTTAAAATTGATAAAAATTAGGAAAATCCTTTTGAAATCTGAACTAAATTTCAAGTAAATGGGCGGCAAACTTTGTATAAAAAAAAAAAGAAAGCTCGCCCACCACTTTTTCAAAATTTCTTGCCGCTATCTTGACTCGAAGGCGCAAAGCCCTAAAACTTTAGAAAACATCCCCGAACAAAAAAGTAATACATCCTTCAAAGTGTATGCCCCCCCGTGTATATGTCACCTGTAGACTCGTCGAAAACGTTTGTGCCACCCGGCTCTTTACCTCGTCTCCTCTTACTCATCATTTTATGCCCCCGTAGCTTTACCGTCGGCTAATGTGGTTCTTAGGGCGTAGGACGCCATTGATTTTGCTCTTTTCAAATTTTAGAATTTATTTCCCGGTCTGATTTCACTCAATTATCAGACACCACATCTTAGTTTTTTGACATGTTCAATGCTGGAAGCAATTTTCGATTTTTTTATCGACCATGGCCTACAGGTAAATTACGGGTCAATTTCCTGAAACGGACGAACATTTTTGAAAGCAAAACAGTTAGTTTCGCTAGAATTTCTGATTTATCGAAATAAAATCGGGCACACCGAACAAAAGTTCGTTTGTGTCAGGAACTTAACGGTACGCACTTTTGCTCGGACAAACCACGTGTGGCTGATTCAAAAATGTCCAACTAAATTGACGTCTTGAAAACATTTTTTACCTGAAAACCGCTAACAATGTCAGGTTAATCCGATTCAAGCGCTATTTTTATAAATCCTGAAAGTTTAAGATTCCACACGTTGTGAGGGAAATTGACACATTTTTAGAAAACCTGACCTCACGGTTAATTTTTAAACACTTCGAGGGCCCAGAAATCCTAGTTTTTTTTCGGGTTATTCATAGTTTTTCTAGAATTTAATTCCACATCTACATTTCTAAACAAAACTTTTGAAGGTCCTTGTAATTCTTCTCTAGTTCTTTATTGTTATGTCTTCTCCAAACTAGGACGAAGCGATAATTACGGGGTTTGTGAGGGAAGTTTGTCGTCGGTCCATTTGTTTTGAAAATGAGAATCGGAACTTTCCTGTCTCCCGTAGAAACCAATTAAACGACAACTTTTTTTTTTCATTTCGTTCATTTTGCAGGCATGCTAGCCTCGTCTATTGGAATTGTTTTGTGAATGCTAGTTGTGATTAAAAAATTAATCGATTTTTTTGTAGTATGAGTTCAAACAAGCCGAAAAAATAGATCAAAACTGAAAATTTTATAAGAAAAATTTCCGTATCTAGTTTTCAATTGGCCAACTTATAATTTATATACTCTCGAAATCAAAAAAAAATGTACTTCCTATATTACCCACAAACATCGAAAGGGAAATCCTCTATTCCCGTCAATTATAAGAAATGTGAGAAAATCTTACTCGATTCATGGTTGCTATGAGACAGATTGCAGATGTTTCACCGGATAAACAAGACGTTATCATTACTTTTCAGTAATGCTCGTTTATTTTTCTATTCCATTTCTCGAATTTTGATAGATGTTGTATTATTTAGAGAGCACTAAATTCTAAGAATGCCATCGTATTGCGCAACGTATTTGCATGAGGCACAAAAAATCTCACAGCGAAAACTACATGACGTAATCCTTTAGCTACTGTAGCGCTTGTGTCGATTTATGTAAATCTTGTCATATATTCGTCGATATAAATTGAAAATTAAGATAAATAATAGATAAGCGAAAAATTAATATCGAAAATCGAGATTCCGTAAATGGACACAAGCGCTACAGTATGTAAAGAATTACTGTAATTTTTGCTACGAGATATTGTGCGCGTCTAATATGTTAATACGCATTTTTAGAGTTTTGCCTGATTATGTAATGCGTATTTCCTCTGCATGCAAGACTAACGATTGGTCTGTAGAGGTCAGTTGGCTGGCTGACTTTTAATACTTATGTTCCTTCAAATGTTCAAGTACGATTAGGAACCCTTTCTCTCATTTCACTAGTTTACCTTAATGTGTGTCTTTGGCTAGCTGAGACGATCATCATTTCTTTTGTTTGTATTTCGCAGGAAAATTGTGAAAAAAATTGCAAAAAATTGAGAGCAAGAAAAGTAAGTGCACACCGATTATGACTCGTTGTACCACGATTTCCCCCTTCGTTTTCCCTCTAATTACCTATACGTATAGGATTAACTAAACATGATCCCGGGGATCACCAGTTCATAGTTTCCTTATCAATTTTATATTACTCGTATGCCTTCCTCGTTTTTTTTTCTAAAGCCATGAAAATGTATCGCAGCGGGTCGTAGCAGGAGCACAATGTACTCGAGCTCGTCACGAAGGCCGTACGGCTGGTTCCGCTTATTAAATGGTTAAAGAACTGGGTCTTGATTCCTACCAAATTCATTTTGATAAATAGTCCCTATAGATCATGTAATAATATAGGTTGACCCTACCGTGTTTTCCAGAATAAAGTTTTACAATAAACTTTATAGCATGGGTGTGCGGCAACGATTTGGGCGACTTCCGTTTTCCGAGATCAAATCCGAGTTTGCTGCACACATGAAAAATGTTTAATTAAGATTTTGCGCAAAATGTAGCCCCTGGTTTACACCTTTTTACGATATTGTGAGTACATTCGAAAAGGATGTTTTGATTGAGTATCCCCAAATCAAAAAAGAAAGTTGATGAGAATTTAAAAACTTTTAAAGAACACATTTTCAGGCACAAGGCCGAACGGCAACCGACTACGCGGGTCAGAACTACGAAGAATGTTATGATAGGTTAGATTCTTTTTCTATTATTCCATTCAGAATATTACGAATTAATGCTTAAAAAAATTTCAAATTAATTTTCGCCGAAATCATCTGCGCCTTAGCTCCACCCAGCTCTCTAGATCGCAACCCGCAATAAAGCCCATAAATCAATGGGCAGCTGCTGCATGGTCCGTAGTGTATTAGTCTGTCGTCTGTCCGATCAGTGCGCTCCCGATAATACTCTCCATTTGTTTCTCGCTTTTTGTAAACTATGTGGTCGACAGACCGTTGAAAGTCGTATCAATTGCACTTTTGTAGTTACCGATAAAATTGCCCAGATCGACGAGTTTTCCATAACAATTTCTCTTCCATTTTCATCTAACATCTGTGACCCCGCTCATTAGTGTTTCTCTAGCCGATGCTATTCCAGGTTCCCATGGCAATGTGTACATGTGTGCCTCGTCGAAAGTGAGCCAAAATGCTCTTTGTATTAGGTTCATTCATCCTATGTTTTTTGTCCTCAGTGACCTGCAACTGCGCAGAGTTAAATATTAATTGGCACTGAAGAGAGGCCGCTCGGGCAAATAATTTTACAAATTGATTTATATTTGAAAAATGAGACACTATGTTATTATCGCCGAATTCGTTCTCTGAGTATCGCTGCGTTCATATCTTTGCACAGCTGCTCTATGAACAATTAAAATAATTTGTGGGTCCTGTAACGAAAAACCCGAAATAAGTCTTGCCTATACAGGAGTTTGTGGAAAGTTTTCAAAATTTTTGATCAACGAAGGAATTTGGAGACGTAATACGATCACTAGCAATCTGAATTTCTACTTTTGTGCCCCAAAATGCTTTTTTCATAAGTCCCATTATCCAAAATCCGGCCACCTTGCTAATCATGATGTCCATAATAGGCATTGAGGCAAATCTAGCGCACTTTTTTGTCCGATGAAAGACTTTTTGATAATACCAAGCTTAAACCTTATTCATATTGCTTTTAGTAATCCTATAAGTTTTGTTTGCAGTGGTTCAGAATTGCCGAACATTCCAAATTTTTTGATAAAGGTTTTACATATATGTTGAGAAAATAAACTCAAAAAAATTAACAATTAGTTCATACGTTATTAATTCCAACGAGTTTTAGTGTAAATATATATGTGGTCCTCTATATATTTTGCGTATTACTATTATTATTGATTCCCTCCAAAGCTGAATGTCAGTCTCAAGACTACCACGTACTGCTCAACTGTGTTGATTCCCTAGTATTTTCAAACGAACAAAAAGTGACAATACAGTATACTTTAAACTAACAAAAAACTTTGTCGAGTCTATCGATCAAACTAGCGAAATCCGCCCGTTAAATCGGTTCTGTTTCCCGCCACCAACACTTATTGTGTTTTCATAGCTTTAACTCTTTGACGGAATTTCCTTTCTTCCGATTTTTCAAGCGATATTTAAGCCCAAAACTTACTTCAAAGAATCTTAAAAGGGATTTTTACAACACTCTGGATCAGATTTTATGAATTGTTTCATTCGCAAGAGAAGAGCGACTCAGTGCTATAAATGGAACATTCACCACACTATCTCCACATTTCATCTCTATTAATTCATACAAGGACACTAAAATAATCCCGGCCCACTTGCTCAGACTCTGTCTCGCGGGGGACAAATTTGAATCCATTCTGTCGGTCGACCATTGAACCCCCACCACACAATATGGTTCAGCGGGGGGAGGTCCAGTTTTATGGCTTGTTATTACGTATACTGCTAGGGGAACCCAATTTTACCGGACCCCGTGCGGAATATTCAAATTGGAGTGTGTGTGTGCAAAAACTTTTATGGTCCATGTCCAGCAGACCAGCCAGCAGCTGCTCCGATCAATTGCCGCTTCAACTTTCTCCACTTTCCCATGGGACATCTAACCTTATTTGTCGTTCTTCTAGTTTCTCCTCTTACTTCTTATTCTTCTTCGTTGCCCAAATTGTGCTCGAAGAACTAGAGATCCTGAATAGAAATAGGAAAAGAGCACGAAGACATTATTTATGTCTTGTTGTCCATGGTTCGCCTCGAGTAGTTGATTAGGAGCTTCTCCTTGTTGTCTTCACTCGGTCGTGTTCTATATTTTATGTCCACTCTTGAATTCCTGGAGTTTTCAGTGCCCGCATTTCCTGGTTGAGCAGTTAGAAAGCTGCAGGAGTTTCCAGAATTTGATCGATTTGCGGAGTCGGCTGTCGTACTACTTACTTCCGGATTATAAAATTCTGAGAATCTCGCGTATTGTACACCATATTTGACGCGTCAAATTATCTCATGGCGAAAACTACAGTAATTTTTACGCGAGAAATAGTCGAGGCCCCCTAAATCTAGAGTTCCAAGAGCTACAGTAGTAATTTGTTCTAACAGAATTACTTCCGAACCTTTCTCATTTTTCAACAATTTTTTAACTTGCGTAGCGGAAAATTAGCGCTAATCGCGTCAAGACCCAAAACAAAGCGCCAATTTCATCAAGAAATTTGATGTAAAAGTTTGTGAAAACAACCGTCACTACTTCTGATGACGAATCCCTACTTCGACCCGGGCCCAGTTCGTTAAACATTTTTGAATTTACTGCCACCACATATCTTACTTCATCGACCAAAATTCAACGTGCTGCGATCATCATCTTCATCTCTGTCTCATCATCTCGCCCAAATTCAATTCCGTCACTGCGGCTCGTACTGATTTTTTTTCATTTGTCAATCATTTAGAGGCCAATGTTAAAGACCTCCTCTCAATTTTTTTCTGTCTGTCATTGACCCCTCTGTTGCGAACCGATTCAGAGTTTACAGGGTAAACAAGCTCGCTTTGTATATAATGTTGATTTATGTGAGCGAGATAGTGAAAGAGAGAAGAGTCTTGTAGCAGGAATCTAAGCGTTTCCTTTGTTTCAAGCTCTGTCAAAGTGTCAATCGCTTTCTAGCTAGATGATTCTTATGAAGCTTTGAACATTCTAGATTTAGTTTGTTACCTTCAACATTGGTGGTCTTTCTTGTCCAGAACTGGATAAGATTTATCGTAGCCTTTTGCGAAACAGTATCAGATTTCCTGCAGGTTGTACAAGGGCTTTCGCGAGGCGGTAAATCGCCTGCCTGACTTTAAGGTGACCTCCGCCTGCCTCTCGCCTCAATACGTTATGCACAAACGGGAACTTTTAAAAAAATTTTTTCAACAAATTGATAAAAAAACAATTTGAAATTTAAGGTCCCTGCCTGCCATAGAAGCCCTACCGTGTTCCACTATTGATGCGCTTCATTCTATTACAAATCAATGTAACGAACTCCGAAGTTTGATAGCCCGAGGCGTTTTCCTTGTTAAGTTGATATCGATTATCAGTTTGACCAACCAAACTCCATCGAGTTGGGTAGATTTTCAAGGAATTTATAGAATTTCGTAGAGTTTTGGACTATGTTTTGCAACGTTGAATGGAATTATATTTGAATAGGATATTGAATAACTTGTTAATGGTTCAAGGATTTTAGCACCCTTTCCGAAGTCTAGAAATGTTCCACCCTCAGGTGCCGATAGTCGGCTCCCGTGAGAACTGTAAACCGATAATCAATCAATATTGCGGGTATTAATTGGCTAATATACATAATCCCCCTGAAAAGTTATGTGAATAACGGCAAACCCCAAGAAAGAAACGACCATTTCCGAGGTGTATCAGAATTTTAACAAGACCTACTTAGGGTACATAACCCTATCAGTTTCAAAAACAGCATGTCGGGATTTTGTGCTACCATGGTAGACAGGCGCGGAGGGTCTGATGCTTGCCTGAAAGCCGGGCAGACAGGCGTTTTAATTGCTGCATGGAAGCCCTAAAATTCCGCATATACGGAACCTAAGCCAATTATCAAATTCTACTTAAAAACTCATTCCACAGGTGTTCCTGTTCTGCTGCATCATCGTCACACAGACACTTACACGCGGCTTTTCTCATTTCCCACTTTTTCTTCGTTTTTCTCGCTTTTTCTTCTTCTCGACACGACTTAATATTCGGATGGATGACGCCGAAAGCCAAAAGTGTTTCCGTCGGCGTTTCCACGCGCACTCGTACTACAAGTGCCACACTTACACACTTGAAGCAAATAGAGAGAGGTGCAGGAGGGAAAGGAGGGGACAACTTCTGTAAGATAAACTACCTCTATTTGAGTAAAGAGTGCAAGAAATATATGCGCGTGTGTCTAATGAGAGGGTCTTGGAGCGATTTTTAAGCATGTACAGTCATGAATCAGGCGGCACGTTCCAGCTTTCAGGCTCTGAAACCGCGTCTGCATACCAGGCAAACCCAACGATGGTTTTTCTTTGCCCTCAGGGATCCGTTTCTTGGATAGTTTTAGTCTTCGTCCTTTTTTCTTTCGTACACTTTTTGTAACTGTTCAATAGTTTCATCTAATCGTAGAAATTCGAGAAAAAGGATTTTTCGAGGGTCTGATAAAAGATCCCAGAATGTGTCTAATTCTAATTCTCTCCAAATGCCCAAAACGAAAATTTTTCGACAGATCCTCGTATTTCGAAATTCAGGAAAACATTCGGCAAAGCTGAAAATGTCACAACTTGCCAAAATGAACAATTTCGGCAAATCAATAGCTGTATTTTTCAGCAACTTTCGGTAAACCGGCAGTTCGCCAAAAAAAATTCGGCGATGGTCTCGACTCTAGAGTTGGGCGGCAGACAATTATTTCGGGCAAACGCAAAAATTAAAAATGGAAATTGGTGTTCGGCAAATCGACAATTCCGGAATTGAGAGTTTCCTGTAAATTCGGCAAACCGTTTGCCGAAGGGCAACTTCTCAGAACTGACACCCCTTCCAAAAGTCCGAAATTTTTTTAGCTTCACCCCCTTCCCTCCCTTCTCCGGGTTTTTTAAAAACCGGACGCACCTCTTACAATTATTACAAACACCACTACCATCGTACGTATTAAACGTCTCTCGTAATAAGGGGGGCCATAATATAATGGTTTTTGTTGTGTTTAGTTAGCCTCCTCTCTACTTCTCCACCATCATCAAAGCTACCCACAATAACATTACGATCATCAACTGACTACTTTTGTCTTTCAATATTTGTAGTTGTTGGGTATTTGAATTCTTATCCACTATATAGCTCCATCCCTATGTTGAAAATTTGAAATTTTTGGTAAATTTGAAAGATACCAAGTTTATGTATATTATAGTATATTATCAAAATTTCCGGTAAATTTATATCCTGCAAACCGCAAACCGACAATTCTAGCCGGAATTGGAAATTCCCGGAAAACCGCAATTTGCCGATAATAAATTTGCCTTTCTTGATTCTAGGTAAAATTTAGTACGTGATCCGTTTTTTCTTTGTAATATTAAAATAGGAATATCAAAATTTTTTATTTTTTTATTGCAACTGCAAATTATGTTCAAATTTTATAAAACAATTGTAAGTGTGAATTTGCACACTAATTAATTTTCTTATTGATAGGTATCAGTTTTACTAGCGGGCTATCATGTATGTACCAAAACGCCTACGGCGCCTTCTGATCTAGTGCGGTGTGACCCGAAAAGTGTCGGAATCATCTTTCGCAGTATGTGGTGCTGAAACCAAGCTTTTGAGTTCTCGCCATAGTGCGGCGAGAGGACGGCATGAGGCGGGAGACAGGCTAGTAGCAGGGCAGGCTTCAGGTACTGTGTCGCGTCTGCCTCCCAATCATTTTTTTTCAAAAAGTTGCAATGGAAATCAGATTTTCAAACGCAACCTGTCTTCCCCTTGTACTATCACAACTTTTACTTGATGATAGTCGATAAAACGCTGGTGTGAACGCGGCGAGGTGTAATCGTGTGACAATACAGCATTATTCTTTTTCGCAAAAAAAAACATTCTTTTGGGTATTATCATTCTACCAACGTATCTTATTTTATCGATTGGTTTTTTCTCCGGCGCGGAAAAGAAAAAATTGAAAAAAAACGTCAAAACAAAAACATTTGGAAAATATAAAGGTGGATATAAAAACGGTTTCGAACTTTTTTTTGCCGCGAACAGAGATTCATTTCCTGTTAACCATTCCTACATCTTTTGACGCTAAAGCAAAACAGAGACAGTCGAGACTGTCACATAAAATATACGTTTTTTGGTATACTTAATTATTCACAGGTGCCCCTTTCTAAAAGTTTAATATTTGTCGCGAAAAAATGCAAGAAATGTTTTTTTTCTTAAAACTAAAAACTCGAACTCAAAAATAATAATTGGGTATTTAAACATTCCGGCATCTGGGTCCAATTTCTTCCCGTTCCTGCCCTTCCATTTTTTTCTTCCTGCACTTACTCGAGTATTCCGGGATCCTCTTCTATTGCTGCCATAAAAGTTCTTCCGCTTCACAGAACTGCAGCGTATCCTGCTTCATATCTCGTTGCTGAACTCCATATAGGTTGTCATAGCTCAGTTTTAGACGGATTCAGGTAAACTCGAACTTAATTTCTGTAGGGTCTCTAGGATGAAGTACAGTAATAAGTATACGATGTGTCAAAAATTTGGCCTAAACTGTCATGACGCTGCTATAGATTACGGTGATAGAAATTTGAATATGTATGAAATAAGTGAAAAAACAGTAGACTGAGCCTTACTCAAATTCACATCCGTTCGAGGGTCCATATTCCTGAGTTGTGAATTTCTGTTGGTTGCAATTGCCGTAACTTATAAGGAAATTGAACAATTTGGAATTTACAGCACAAAATTAGTTTGGTGCTTCTAGAGCCCATTTTATAAAATATATACTTGACACGTGGCACTAATAACAACATCTCAAGAAATTCAGGAACCACAATCGTTTCAGTCCGAAGAAGAGTGTGGCGATCGGCAGGCGTGCCGCAGCGAATGGATCGGGTGCTGCTCAACTCGAGTCGGGAAGATCGCCATCCTGGTCATGTCAATCATTGTATTATATCTTATCATATCAGGTTGGTTTAAATATATTACTCAAATTTATCTGAGTTTACAGGACAATGAATGGCTGTCAGCATTAACGCCCTCCGACTCACCACAGGCAGACGGACCTCAACGAGCCGCGGCCTGGTATTAATTTAACAAGGTGTGATTGGGATATTACTATTGTGGGAAATTGCTCGATAATTCCACACTTATTGAGTTCACAATTAATTTCTACTTTATTAACTGTGTTTTTGGTAAAGACACTTTTTCCCCTCCCAACGATAATTCTCCTAGATTTTTTATAAACTTACGACATACTTATGAAGCAACGACTTGATGCGCAAATCGCAAAAAAAAAACAGAAAAATAACTATTTTATGAATATTACCATTATCGTATGGTGTCGTCTGTTTTGTTGTTAGTTTTTTTTTACTCGAAATTTTCTTAAAACACCGAATTCCACATTGAATCAAATTTCTTAATAATTTATTAGACAATTGGCGACTTTACAGAGCCAATCTCGGCAAGTACTCACCGGATGTATTATGTGATGCCTATGAGCGAGCAGACGTTTCCGGAGACTATTGTAATCGACTTTGCTATGATCGAAACTGGAGTTACTTGTCACTGACTAGTTTACGAAGGGCGGAACAAGACTGTGGTCATAGTGAAAGATGGCGGATAGATTGCTGTCTATAAAAGCACCCAATGTTGATGGATCACTTCGACGAGCCGAAAGACATCTGACGGATGCCCAGAGTTCTCTGATCGAGTAGTAGATATGGTGAATGATGAGCTGAGATTCGGATGGCCGAAACACTATCGACGGAGCAACATTTAATGGGGACTGTGGCCGACACACTGTTACGGACCAGGGAGAAGCCATGTCGAAAGCGGATCGATCCTTGTGGGCTTTGTTCAAGCAGCCTGAATTCATCCTGTGCCGAGTGTTACCGTTGAGACGTGTCACGCCGAAGCTCTTTGGGACGTGTGAGTATCAGACTGAGTCACTGGTGGTGTTCAAGATGAAAGGGTATTATACGAATTTGAAGGTGGTTGGGGATTTTTTTTTAAATTGATTTTAAAAATAAAATTTTCGCTCAATCCAAATTTACAGGCAAAAATCTTGGTGCATGTCATGGGAACCCTGAAGCTCTTATACGAATTTCTCGACGAACCCCCAATGGTGTGTTCGATTTGATCTCGGGTTAGCAGCAGCTTATGTCCGAAAAGGTAGGTCCGCCTGTTTTTTTATTTGATTTTTTTTTCCGAAAGAACCTCCATTAATTATTCGAAACTTAATTTAAAAGTTATTATGAATGATTTTTTAAACAAATTTAAAAATTGATGATAATCCAACAGGCCGGAAACTCAAACTGTGAAAACTGTCCCGTAAAACTCCATATTTCTCAATTTTTCTGCAGATTCGTTCTAATGGACGGTGACATACACGAAATCGACTGACAATTGGATTCTCTCCTAAAAGGACGTCTGTGTGAAAGTGATAATGATTTAAGAGTAAAGTACTTGGAGACTGTGAGGCGAGATGCATTTCTAATATGGTGTGGTCGGCGAGGAGTAACGGGAATGGTAAGCTTGAAAGTTGTATGAAGTTTGGAAAAATTGTGAAAAATCAATAAAATCGGCAAAAATAACTAGCTTTTTTCCAGATGGCCGAACTTGTTTTGCATCGTCACCTGTGGAAAAAATTGCTAATAATGCAACAGCATCTTGATGTTTTAGTATTCATAAAAAAATAAATTCGACAAAAACCTTTTTGATTTTTCCAAAAATCAAAATCACATTCTGATGCTCAAATTGAATTTTCAAAAAAAAATATAGAAATTTCTTTTTTAATGCTCAACAAACGAACGAATGTCAAAAAAAAAAGAAGTGAATTTTCCGAATTTTTTCGCTTAAAGAAAAACTGAAAATTTGAGGAATTTCAGTCAGAAATATTTTTTTTTTGATTGAAAGGATTTTATTTTATAGAATTTAACTTCCACTATTAGAAATTACCTATTTACTTAGTAATAGGAAAGTTGTGAAAATGTTAGGAAAATTTTTTTCAACTGTACAATTTCCCGGACAGGCCTGTCGTTCCTTTTTTTCACAACGTAAAAGAAAAAATTAATTAAAAAGTTCAAACTCCTAGTATTTATACATTGATTTTGCTTTAAAACAAAGTTTTTCTTGATTTTTTTGTGTAAAAATTGCAAAAAAATCCAAATTTTGTAGGTCTTCAGCGATAAACTGGTCAACATTCGCTCGTTACAATGGTCCAAAAATAAAAAATATTTGGTCGCATGCCGGGATACAGTAGAAAACAACTGGACTCAACGAATTACGGTTAACAGGGTGGGAATCTGCCGGATGTTTAAAGGAATCTAGCTCTATTCTTTTTTTTTTTCTTCTACTCCATGTGTCAAAAAATCCCCATGTCTTATGATTTTCTGGTGCTTTTTTCCATATTTTGCTTTTTTTGTGTTCTGGTTCATTTTTCCATGGCTCACAGAGCCCGAAAGGAACTTAGGATTTTCAAATTTTTCGTTTTTTTCTCATAAGTCTGTCATCATTTTTTGCTCTGCATCATCATCGTCATCGTCAACTTCATCTTAAAGGTTTTATTAAGGGGTATTATTACACTTTCCTCGAAAAATTTTGACGAACGTATATGTATGCTTCCCCTGCACTGTCTCCTTGCATTTGTACCTTCATTGTTACGGGTTTCAAGTTTTAAAACTGTGAATTTATATCGAAGAATTTTAATTTAAAAAAAAACTTTGTTTCCTTTTATGAATTGTTACAGACAAATTTTTTCTCGGCTTGAAAACTGAAGAATCCTAACCCTGACTAAACTAACTATATGTGTTGGGTATCAGCGTGTATTGGTCCACCCACGACGTCATGGCTAAGAAGATCGTACAACGTGAACTCTATGAACTAACTCTTTATTCCTTAGTTTAGTACACGCTAATAAACTACTCGTCTTTTCCTCCTCGTCTCCGAATACACAACATTATGAAAAGAGTTTTTCTTAAGATAAGAAATGTTCTAAAAAATCGATGGCCGAGTTTCCTGTTTACGCGGGCGCAACAGTAAAAAAGTGTTAACACAAGTGAGAAAACTAGACGACATTTATTTTCAAATTTCACCCGATTTCAAAATGTCAACAAAAAAGTCACAAAATTTAAAATATGAACAATCAATATCCCGCTGGCGCTGACTCCTCCCCTTATCCGAACTGTTCGCAGAGATTTGCCGTCGGAAAGTCGTTCGGCGGCGGTAACAATTGTCAAATTGTTCACTACCTCCATTACGTGGTGAACCACGATCGATCAGGGATTTCAAGACGTAGGTTCGGGAAGTATGGTACCACGTGTAATTTGGCTAAAAAATGAGAGGAAATTGGGAAAGGTTTTGATTTTATTGATTGAAAAATTTCATGTGAAAGTGGAAAATTGATTGATAATTAAATTCAGAAGTTTTTTTTTTGAAAATTATTGATTTTTATTTTTGAGAAATCCACTCTTTTACTTATCGCTTTAACGAACGAAAAAACAATCAAATTTCGCGGGCTCTTAACTGCTTGTGCATCACTTGGAGCATCAACAGCTTGTTTAACATCTGCTTTCAGCCATAACCAGTGCAAATCCAGCAACACCCGAAATAATGGTGGATCCACCGGCTCCGCGACCGCCATAAGCTCCGCCCCTTTTGTGTTAAAGATCACTAATGGGCACTTTGACTACTCGCCTGATGCGTTTTCCAGGGCGAATGAAATTGGCGGGAGACGGTGGGAAACCGAAGAAAAAATTCGGAGGACCGGGAGTGGAACGTCCATTCGTTATTCCACAGAATTCCCGTCGATTCGGAGGATACTAGGCCACCAAGGCTGGAAGAATTTGAGATGGTGGACATAGAGTTTTTTTGGCGTGGCCGAGAAAATGTCTTCATATCCGAAAAAGTAAAAGCGATGGCCTAACAGAAATTTATGTGGCCACCATATAAACCGATTTGAACTGAATTCTGGCCTAAAAATGAAAGATTCGTCGTCCTAAAAATGTTTTTAATGATTGGGCCTAGAATTGAAAGGCATGTGATGGCCTCCAAATTTCAGGTGGGCACCTATATAGACTTTGGTTGATAGAAATTACACGTGGTCCAGATTATGAAATCACTGCGGTATAAAATCCAGGTCTAGGAAAACAATTTACTAAGACTGCCTACCAAATCATCCCCTGGCCTAATTCGTTTAAATTTTTGGTGACGACCTCGAACTTGTTCATTTTTATCAACTGCAGAAGCCTTGCTAGTCGACTGAGGACACCTTCTCACTTTTGGCGCTGGCCGAGTTTTCGAAGGTCGGCGACCAAAAATTTCCTTTAAAAAAGCAACTCACTATAAGTTAATGGTTAACGGTCGAAACGGCATTGCTGTCTGCATCGATAATCGATACATGAGTTGTTCCATCCTGCGGCGGTGCTCGATCCTCCATAGTAATCATCAGGATGCGTCGTGTCTGTGATCTTCGACACTAACCCAATCCGCCCACTTTTGACGTAAAATTTTTTTTACGTCGTTTGCCACAGAATTTCGGGTCGCCAAGCCAGCTTCTAGCCGCATAACTAAATTTGCCGACTTACATTCCAGATAATGATGGGTCGTATAACGTTGCGATTTCGTTGAAGACTTCATGTTATATTCGAAGCGGGCCATCCATCACGTTAAGTATTGCCTGAGCCACCGCTGAGCCCGAGGGAGGCGGCCGCAGACCCCGCACCCGTTTTTCAGCTTTGTGTAGATCACATTTTTTGAGTCCTGGACTATTCATTTGTATTTGTTGATGTCCTGAAGCCGGATGATCCCACCGTTGGCTTCGAACTATTTGGCGAGTTGCTCGGCGAGCCGACCTGTATAAAAGTCGGCGCCATGATGGGATCTGTGACTGAGTTTGCGAGCAGCCGGAATGTCTCTAGGAGCTTTTTGGACGCGGGTTTTTATCTGGTCTCCTGGTTGGAAGACACGCTGAGTTTCGGGGTAGATGAAGTTTTTCATGGTGGGCTCCGCGCGGATTTGGTTAGGTGCTCGTTTTGGTTGAGATGCTTTTGCAAGGTCATGGGTGACATTGGGTAGCCTGGAATTTTTTAGGATGGCCTAGAAACGCCATGAACCGATAACATAGTTACTTATTTTGTGACCTCGAAATTTTCATGATGGCTTAGAAATTTTATGATGACCTAGAATTTCTAGCTGACCTAGTAATTTTTTGATGTCTCGAAATTATTAGTAATGTAATAAACTACTCGTCTTCTCCTCCTATGCAAAAATTTGGGCCCATCTCCCTTCGTGGTGAGACCGATCGAGGCGAGACCTGCCCATCGTGGCGAGACCCATCGTGACGAGACCCATCGTGACGAGGCCTATCGTGGTGAGACCCATCGTGGCGAGACCCTACGTTGAGAAACCCATCGTGATGAGTCGACCCATCGCCATGGTGAGACACGCCGTGGTGAGACTTATTGTGATACTGTTAACGTACACAGTAATTGGAGAAACTTTTAAACTGATTTTTACAAAGAGTTCAACATTTAACTTACCAAGAGCTCAATCCGTTGCCTCGCTTTTTGTTGCGGGATTATTGTTCTGTTGCCTCCATTTCCGTTACCCCTGTTGTGTTGCCTTCGACCAGCGATGAATCCGTTGACCCCCCCCTTTTTCGTTGTCCCCGGGGAATATTAAATCGGTTGCCCCCGTTATCCGTTCCTAGGGCTTGTTGGCCGGTCTAAAAACGGCCACCAGAAAATTTATCAGAAATGTTCTACCGTTAGGAGTTTTTTAGCAGAAATATGCTACCGTCGCAGGAAAAGTGCCCACCTTCAGCCAAAACCCTAATCAATAGTTGGTTTCAACAACCCGAATGTCTCCACTCGTTCCATTTCCGAATCTCTCGAATCCGGAGGCCGTGAAGCTCTCCGGGCACCGCAATCGCCTTCCATATTCTCGACTGATTCCACGTTTGTCACGGTACATTTCCTCTGTTGCGCGGCGACGGGGCAATCTCCCAAGCATCGATTACCGTACACTCTTTTGTGTTCTGGAAGAATTTTAGAGGTTTATAAATCATTGATAATATTTATAGGCCACGGCACAAAGAAGTTTCTAAAGGACACACGCGCTCCTGGCATTTCCTCATAATAGATTTTGAAATGGAAGAGTGCCGAGTTAGCCCGTTTGGACTACGTCCGGGGTAAATTACGGAGGGCGTGCAGACTTGTTAATGGAGCGCGAGAAAAACGCTTGAAGGCCAGAAACCAACAAGGTGAGGCCACAATCATGATGTTTCCAAAAATGTTATTAATAGGAAGATCATTCTTTTGTCTTCCGAAATTTTTCTTCTTTGTTTTCCTGTATTTCGATTATTGACTTTTAGTTGAAGAATCAATACTAATTATCTTTTTTAATTATTGATGTTCCGCTCCAATTCGTGGCGAGACCAACAACTCACGCATTATAAATGTCATAAAATTTCCGCCGCCAATTCCGGCCGAATGTGTATCAATTGCACCGATACAGAAAAGTGCGGCGATTGCCGAATCCACCGCATGTCCGCCTTTCAGCAAAATATTCCGACCGATTTCTGAGCAAATTTCGTTGTCGGCGGCGACGGCCGCTTTCGAATATTTTCGAGTGGAGAAAGTGCTGGTCCAGGCCAACGGGGGAGGCGGGCATTGTGTCTGGAACCTTGCCGAGTTTTATTTTTATGACGGCCACGTAAAATCCAGCCATGAACCGACAGCGGACTATTCTTCCTTTCACCCTCGTGGCCTAGCTTTCTAACAAGCCGGCATTAGTAAATCGGAAAATACAATGAAGCGAATGCGAGTCCTTTGAGATTAACATCGTTCGATTACGAGAACCGTTAAGCCGACCGCCGCGCGGCCTAAAGTACGGATTTTCATGGGTTGCTCGGCCTCGATAAGCGGCTCAACTTCATCAAATGGTCGATATTCTGGCTGTAAATTATCATCGTCCGGAAACGTGTTGTAGTATTGAACAGGAGGTGGGTTACTGCTGAAAAGTCGAGTTTTGGGCGTCAAATTTGATGCATTGAGTGGCCTGATCACGATAATTACAAGATCGCGACATTTTAAGAAGGCGTATTGCACAACATTTTTCACGCGCAGAAATCTCGTAGCGAAAACTACAGAACTGTTTAAATCACGGTAAAGCTTGTGTCGATTTCCGCGGTTTCGGTTTTTTCATTTTTTTTTGTGTTTTTTAATTTAAAACAATTTATCGACTAATGAATGATTTCCGTAGAAATAGACACAAACACTACAGTCATTTAAAGAATTATTCGTAGTTTTTGCTCCTAGATATTTTGCGCTTCGAATATGTTGCGCAATACGCATTCTCAGAATTTTAGTGTTGCCATAATAATTCTAAATTTAAAAATGGAATTTTCAAAATCAGAGGTTTCCCAAAAATTTGAATATTCCACCAAGCATAAAGATGAATCTGAGAGTATTCAATTTTTTGAGCAAATAATCGATTTTCTGGATTAAAAAATTGCGTTGAATTTATAGATTTCTAGTAAAATTTGAATCTGTGCAATCTCAGACTAAAATGTATCGATTTTGATCGACTTTTCATAAAATTTAATTTAATTTTCGAAATTCCCAAAATATTGCCTGTTTTTCATCCCAAAAAAGTCGTATCAGTTTTTTCAACAAATTAGCGAAATTTTAATCGAAAGTTGTTTTCAGAGCATCATGATTTTTGAAAGAATTTGCAAATGTGAGAACTAAAGTACTCCCTTAAAGGCGCACGCTTGTTTTATTTTTAAAAAATTGGTCGTTTCGAGACCTGGTACCGTATATTCGCATTTGGGTAATATTCCCAGCATTATAAATTGTAAAAACAATGCACTTTTTAAATCTTGAATGCATATATTTATTTTTTTCAGAAACTCATGTCGCCTTCGGTCTCGATTCGAATTTATTCTCACAAACGTATAATATTTTCTCGAAAAACCCGCGAATTCTTGTAACATTATTGATTCTCACCGCGTAGATTGCCCTTCATCATTAATCAGAATTGAGTATGAATTAAAAAATCATAGAAAAGTCCAAGCGCTGTCTATTGGAATAGGACGAGAATGCCAAATTGCAACTTTGGCTTCAAGATAACGGAAAATCTTCTATCGCAAAACGCACTAGATAAGAGCTACAGTTTGCTGCGTGTAAGCGCCCTCCACGACAATGACAAACGAGAAGGGAAGAGAAGAGGGGGTAACCGCCAATAGCTCTCTGTATCGAGGATAGTCTTCAAGTGACAGAAGTGAGATATTCTGTGGGGAGAGAGTTGGGAGGAAGGGGGAACAGCGTATAAGGACTACGGAAGAGTGACTTGTAGATTTGGTGTATACGAGAAAGTGGAGGTTTTGGCTGAAAGTCTTTTATTTTCAAAAACTTTTACTTGTAACAACTAACGAGTAGATTTGACAATGAGGATAATATTCAACACAACAGAAAAAAAGTCGATGGGTAACTAATATAAATTAGAGAAAATGTGGCATCGGGGAGAAGTGGGAACAAAAGAAGAAACTGATGATGATGATAGGAGGATAGCCGCGAAACAAGCGATTAACAGAGAACAAGATTCATTTCGGTGAAGATAGAATAACAGCAAAAAAAAAAACAACAACAAAAGTCTAGGTCTTATTGCCCATTGAGAGCTATGCTGAAGGACACTGGTAAGGTGCTCGTCGATTACATCTTGCTGCGCGAATTGTGGGAACGATGCGTACATTCAGGATTGTGACAATTCTTTGCTTGGTTTGGTTGCCGCTATCGTCGTCGCGAGGTTGAAAGAGCCATCGTTGGTGATTGAGAGCAAGCCTGCAAAATACAAATAAATAAAATAAGTTACGGATTTTTTTAGATTAGAACTTACAAACAACGAAGATTCTCGGAAGATCTGATTTTCTGGTCCAAAAAGTGCGGCGTTTATCAAACAATTCGGCGAGACAGGTGTATATGTAGGGGCTTTCCTCGGTGTCTGAATATGGTGGCAACCAGCTCAGGAACAGCTCTACGACCTGGAAATAATATGGAACTTTTTTCTTAACTGAAGTTCTAAAAGCAACCTTTCCGTAGGAAGGTCTTCAGAAAGGCAGGAAGTGGCACATTGCGATTTTGGCTAATGCAGAAATCGCGTTTTCCGTGGCAATTTACAGTGCTCTCCTCGGTGGCGCGTCCTCTCGTTGAATCATGGCGGCCAGTGGCCCCAAACAGCCCAAAAACTCGTTTCGTGGTGGCTGATCTGGCGCTAGTTGATGGACATAACTCCGAAACCGTAGCTCGCTTCTGGTCTCACTTCAGGATACTCCTGATCTCCCAACAACATGTACATTATTGGGAAATAAGCTTCGGGAAGTGAATTGGGATATGTCCGTAACACCGAACTCGATGGCGTCATCGAGTCTCATGGCACATTCCCCACTTGTCTCTCCAAGTTGTTTGAATCCCTCGATGAGTTGAACGGCACATTTGAACATGTTGATCATTCCCTCGAAGATAGTTCGCTTGGACTCCTTCATAAGCTGAGAGAGAGTCAAAATCGATGGCCTCTCCAAGGCCTGAGGCCTCCATTATTCCATGAAATAATCGAAATGAGCTCCTCATTAGCTTTACAGCATTCCCTATTCATCGTCATCTTCATCTTCAACTGGACGATCGCTCATTCTCTTTAGTTTTCTGCTCGAGCAGCACCGAAATGATGAGTTGAAACTCTTCTAGATCTCGGCGATCCCCTCAGTTTTCATCCTCAATGAGCCGATGGTCGTCATGTACGAGGCGAGAATCTCGACATCGTCCTCCTCCTCCGACGTCAATGCCTTCAAGAACTCGCACCAACAAACGACGCTTGACAGCCAATCCTTGCCAACACAGGTCAACAAGCATGGCATGATTTCAGCGCCCGTACGGAAACTCCGTCGTGAAGCCCGAAATACATCCGAGATTCTTGATGGCGTGCTGGTAGTCGACGGCGTGTGGCATGAAAGCCTCTGGCCTTCATGTCCTTGGAAATCGAACGCGACAAGCATATCGCAAGCAGTTGCCTTTTCCTCAACACCTCTGGTGCGGATTCCGACAGTCTTTTCTCCTCCGATTCAGTGGTATTCAACTCACTTCCTCGTTTTCGTGAACATCTTCGTCTGAAATTTATATATTTTTTTAACACGTAAAACTAAAAAACACTCACTGTTGAATATATTGAATTCTAGGCGGTAACGAGCGGCAAGAAATGGATCCATGACACCTGGGAGGAATGGTGCGAAATCGGCTCCAAGAAAAGAGCAGAAACGAGTCCATGAGCTGATCATGTAGCTGTATTGTGGATCACCGATAGCCAAATCACGACTTCATGTCTCCGAGAAGGTTCAGGATCTCTTCGATTGCAGTAGGGTGGAATTGTTCCTTTCCGACAGCATATCCGATATGAGAGAGATGCATTCGATCGTCTTTCCTCTCAACTCCTTGAGCTCTCCGACGTTTTGAAGAATGTGAACGAGGTTCGGGATGAGGCGAGGCCATGATGTTCCTTGAAGAGCTCCTCGGCGGCTTCAGCGACGGAGGCGATGGGCAACGGTGACGATGTTCTCAACGACAACCTGTTATGTCTTGTCTCCGACACGAATTGAACAGAGCGGAACAGCATCATTTTCGAGTTTCTGAAGAATGAGTAATGGAAGCTATTGTCCAATGATTTTCACTCCTCAAAGTTGACAAGAACCGAAGCGGCATGAACAGACACGTGGAACATCGGTTCTCTAAACTCGACAAGAGCTGGGTATGACGGCGGCGTGGCACTTCTTCTGAAGAGTTGGAACGAAGTCAGAAGACATTTGTCCGATGGCGTTGCAAGCCTCGTATTGAACTCTTGGATGAGCTTGACGTAATTGGTGATATGAGCCATAATTTGCTCTATGTGCTGGTTCCACAGATCTCACCCTTAAGGCGGACAGGCGAAGAGCCGCGTGCTTCATCTTCCAGTCTTCGCTGGTCAATAGCTTCTCGACAAGTGGAAACACTGGGAGCACCACCTTTCCGTTGAGGCAGCAAGCAACACGGTAGATGACGCGCTTTCGGCGATGATTGGGATACTGAAAAATAATTTAATTGAAGAGAAAAACTAGAAATCTTAATCTTCATAGTCTTCTTCCTCTTCGATCTCGTTGAGCCACTCATTGAGCACATCGTCATCCATTTCGGTCATGCAGGAAAGAAGAGTCTCGAGTTGGTCCAAGAGTTCACTGCTGGTTACGCGTATTTCTTGAGTCCTTTTGGTGCGCCAAGTACGGGCAAATATACTTCGATGGCGTTCTGACGGACCATCTCGTCCTTTTCCTTGTATCCAGCATGAAATCTGAAAAAATTAAATTTTTAAATGGGGCCATTTATATTACTTACAGCAAGAGTGACTTGAAGAACCTCGGCTGAGACCATATGAGTGTTAAGGCATTTTGGCAGAGAAGAGGCGGGCTCGGCGAACTCTCCGAGTCGTCCATGTGTCCGCGTCGCTGGTTTCATCGCAAACTTGAAGGCTGAACATTGGAACAAGAGAGGTAGCCTGACACTTCTCCTCATCATTATCAACAGCGAAAGCGCTAACAGCACGGACGGCGGTGGCCCTTGATTTGCAAATCCGGTGTAAGCCATCAGCACTTTTCCAAGCTTTTTGGAAGGATCTCAATGGGCCAGCCTGTTTCCAAAAATTATTGAGGATCTGCGAAGAAGAAGCAGGGCTATGTAGTTTCCGGTAAGATCCTCTTCAAACCATGATCCATCAGCGGATCGAGGACTCCTCCCCATGTCATATCTCTCGTGCGATGAGGTTTGAAGCGATTTACGGCAGAGGTATCAAATCAGCAATCTTCTTCTTAACCGAGAGTTCGGCGTGAACTATGCAGCCATCTCGAGAACTCTGTCGAGAATGTGCTGTTCTGCTCGTTCTGCGCAGCGTTTCTCGCATCCCAGTCGCTGGCGAGAACTCGTCGCAACCAAAACTGATCTGGCCTGAAAATCGAAAATTCCTGGACTATATACGAATTGAGTGAACTAACATCAGAATTATTCGTGTGGTGGGTGTAGGCCTGGAAAAGTGCAGCTACTCTTCCTTGGTTGGTGTCCTTCAGACGCATCTTTTCATAGACTTCTTCAGCTTGTTTTCGGATATCATTGTCTGCTGACTGCAGTTCTGTTGAGCTCATGCGTGAAACCTTGATTGACGTCCATTGTAGGGCACCCTGAAAATCAGAATATGTGCTAAAAATCCCTCTTCACAATTGAGAAGGATACTAAAGGATGAAAGCTAGTCGGTTTTGCAGATTAACGCCAGACCGGGAATACGCGGAATCTCGATGAGCACTCGAAAATAGATTTTTACTATAAGAATTGTCATTTGCAACAAAACCTATCGTAAAATGTGAAAGATAGGCCAACAATTATTGATTTGGGACAAAAACGCCTCGAGTGCACGATTCTTAACGGAGCGCACTTGCTGCGTCACACGCACCTTAAACTGTACACGGCGGGAAGTTCCAGTTATTAAAAGGATTCCCGTGATTTTCACGACATTTACTGGTTTTTTCAGCGAGTTTTCGCATCTTTTCTGCGACAAGCGATGATTATTAATGTTTGGAATATATGATATGGTAGCGTGTTGCGATATAAAAAATCGATGGAATGAGTCCGCATCAAGAGAAACTAATATCTGCATAGATCGCACTGTTTGCAATTTTGGCTACATTGGCCAGTTCACTGACAAAAAAAGAAAAAAAAACGGCAACATGAAATCTCTAGTACCTATTCCAGGCAACCAGTGTCTGGCGACGATGGAGTGTAATTCTGAAAGACGCAGTATTGAAAAGAGTGTGTTTTTCGCTTTTTTTTTCAGACAGACGAGTCAAAAGAGTAAATACGTCTCAGTAGTACAAACAATGTGCGGCTGCGAAATCAGTAAAAATTAACGACTTGTGATACAAATTCCTCAAGGAATGAAGGAGAAAGTGTACTTATTTTTGAGACCCGAAGAGCTCGGGGGATGTACAATTGGGGGGATTACCAACTCGATTGGCCCCGCCCACAGAACCCGACGTGGCTTGCAATACGCCCATTTCTGCAACTGCCGCACGGTTTTAAAACTGTACTTTTCTCAATAGAGCGAGATTAAGAAGAAAAAATAATAAACCGTGCGGCAGTTGCGGACATGGGCGTATTTTGGGGCAAGCCACGGTTCTGTGGGCGGGGCCAAACTCCCGAATTGGTAATCCCCCCAATTGACATCCCCCTCTTCGGGTCTCCTGTTTTTTAATTTTGAATTGAAAAATTGTCCAAGCGCACACGTAGAACATCAAAACCAGTGGAGGGGCGAAATTTGATAGATCGCATGTGCAAGAATGAGCATTCTACGAGTTGAAGTCGCGCCACTGCTGCGTAATCGGGCGCGCACAATATTGTGCAATAAATCTCGGTTATTTGCGTACATGCATCATAGCTTAGACGCGCAAATCATATTAGAAATTTCCCCGAAACACGGGGAGGCAAAGCTAACGTGGCCGAAGAAATTGGGTCTACAGTAGTCCCATTTGGCTACTGAATATTCAACGCGAATAAGTTTTGTACACTATTGCGTACTTTGCGTACGGTAACGCATTTTATGCATTGACGACAATTCGTCAATTTCAGCTCAGCCTAAAAGCGCTTTTCGTCATTATGTGAGCGAATAAAAGTCGAAAAAAACTGTTGTTGTAGAGAAAGTAATTTAATAAATAAAAAAGTGCATGTTTTATGTTTCTCATTATGTTTCCACTGATTTTCTTAGAAAAACCGACAATTTCCTCGTTTTTCGAAGAATTTCCGCTGAATAGTTTGTTTTTATCTAGTTTTTCTTCCGATACTGAATAAGACATTTAATAACATCAAATATAACGTTAAAAACATTAATTGTCTCGAAAACCAATATAAAACTCGTCAGAGAGGGATACTTAGTAGATATGCTGAACAAGGAAAAGAGAGAGAAGAACATTAACCTGAGAGGGGGGAATAAGAAATCTGAACAGGAACGAAATAAGAACATTATTAGAAAGAACCATGGTTCCCTTGATCTTCTTGGCAGTCGTCTCCTTATCCTATCACTTCTTCTCGGCGTCCTTCTGATCACGCTACCGAGCAACGTGGCACGATCGAAGGGTTTCACAAGCACGGTTCGATACCGCTCCACGAGGGGGCTCCCAATTCAGCGAGCCATGGTCCTCTCACGAAGTTGAATTTTTTAAAATTAAAAAATAAGTAACGTCAAGAATTCCATCGAATTTGTGCTCCTTTGCAATAAGACAAATTTTTTTTAACGGACTTGAACAGGATCATTGACGGCATGAAAACGGCTTCCTCGTTGAACCATGTTGAAGCTCCTTCACCAATGCACCTGAAACAACTTCTAAATTTCAATTTAAAGAAAATCCACACACTTATCCGTCGGAAACGAATCCAATATTCTGGTTGCTGAGTGGAATTGCTTCAATTGATCTGTTTTTTTTTGAAATATTCGATCACACATCTTGTATCCACCAGATCGCTGAGTGCTTTATGATTCAGAGTCGCGCTTGCCAACCTCTTCCATCAGCACTTCTTCTGCTTGGAATTTTGATTGCTTTCGGACCGATTGACTTGTAGTTTCTTCTAATAGTCGCTGATTGAGCAGTCGACCTTGCAGTCCTACCGAGTTCTTTGGCTTCTCCTGCGGCACTTGAGCCCTTGTAAGAGCAGTTGAAATTGCTGCTTAACCTTCCTTATTAATAACTTCTTCTTGTTCGCATCTATTTCGAATTTTGTCTTGAAATCTTCCAAAGCAGCGACAACGTAATATCTGGAAATTATAAAAACATTAAAAATATTTTGAAAAAAAATCGAAAATGGCTGTATTCCTAAATTTTTTATTAAAAAAAAAAATGAGATACGTGAGTTATCATTGAGTTTTGAGAATTAAATCAGCATATATTTCTCCATATTTGAGTAGGTTATCAGAAATATTTACCATAATTTTTGGAAAAATGTAATTTTTAATTCGAAATTCGCACCGAATTTCGCGAATTTTTCACTAAAATCGAGAAAATAAATATGAAATACGCGTGTTTGAGGTTCAAGGCTTTTTAATTCGGAATCAGCATATATTTTTCGATATTTGAGTAGATTTTCAGAAATATTGTACCATAATTTTTCGAGATTGATAATTTTGAATAATAACTTACTCTACGATTTTGCCTTTGTCCGTTTCAATCCTCGAATTTCGAAGCGGTTTGCGTAGATTAGCTGAAATCATTATGCTTATCCCACGTAGTAACAAGGAAAAACAAGAAAAAATAAGCAAAAACGTGGAAAGAAAAATAATAGCATATCAGTCAAATTAAAAATGTTTATTCGATCAAAATTCTTAACCATAGGAGGCGGTGGACTCTAGCGGGCGCACTCTCGCGGCCACGTTAGCTTTTCCCCGTGGAAAGGAGCCATGATAACGGAAACACTATTTTCTGAGCACCCGAAATATATCGTAGCGAAAGCTACAGTAACCCTTTCAATGACTACTGTAGGGCTGGTGTCGATCTTTACGGGCGTTCATTTTTAAAATCATTTTTTTAATCTGTTTTTTGTGTGCGTCACTGTCGATGACTAAATTATAAATTAATTTCCGTAAATCGACATACAATCGCTACAGTAGGTTCATTTAAAGAATTACTAGTTGTTCGCTACGAGATATTTTGCGCGTCACTCCTTAGGTTCAGGCCACCAATTGTCTTACACTCAAAATCGACGTGAATTTCTGTGTATTTGACAGCAAAAGTGACGTGACAAACAATTAAATAAGGCAATTTGAAGAGTAAAAAACTGGGGAACGATGTGAGATAAGCCAAGAAGAAGCGGGGCTTCGACAACGTATACTAATCAGAGATGGAAAGTAAGAAATCAACTTGAAATTTAAGACAAAAAAGTCAACGGGGGATTTTTTTTAGAGAGAAGCGAGTAATCGGGCACAGCAGGCCAGAGAAATAAAAAGATAATAAACAATTGAAAAAATATATATATCGAAGGGGGAAATTATTGCTGAATAGACTGCAAAGAGGTGATCGGACGGTACAGATAAACGAAGTGTCTCTGGACAATTCCGGGTCCACGGACAAGAACGGCCTGCGCACAGTAGGCCTTGTGGTTGACGATGTTGGCAGCGACGGCCGGATGCTTGGGAGCGTAACTCAGACGACAGAATGGGTTCACAAATTCTCCCCGGCGTTGTACATTGAAGCTTGCTCTTCTTCTGCTGATAGGACGGCTTCGCGGAGGCTGAAGCAGCTTCCAGCGGCATTGCCACCTCGTATGACAAAATGTTCCGTATTGACCAGTGCAAAAAAAATTTTATGAGAAATTGAATTTAAAATGATTTTATTTGTAATTTACTTGTTTTGTTAATTGGTTCGATAATTGTTTTTTTTTTGGGAAAAAACCGAAAAAAAAATTAAAATCTTTCATTTTTCATTTAATTTTTTTGTTGAAAAATCGGCAGTTTTCGATTTTTTTTGAAAGAATAGGGAAAAGTCAGTAATTGTCGATTTTTCAAAAAACTGAAAATTCCAGATTTTGTCAGGACAAAAAACGAGGAATTCGACAATATTTCAATTTTATTTTTTTAAATTTGCGTTTCTCAAATTTTTTTTTGATATGTGATTTTTCCGTAACTTTTCTCTGGAAAAAAACCGACAAATTTGCAATTTTTCAATTTTTTCCAAAAAAATCTAAAAATAGAAAATTTTCGATTTTTCCTTTTCTGAAATATTTAAAGTAACTTCCTATTTTTTTTAAACGCGTATTAAAATTTAAAAAAAAAATCGGAGAAAAAAAATGAATCGAAAATACGATTTTCAATTTCCTTTGAAAAAAATAGAAAAAATCGTAGGAAAATTTTCGTTTTTCGATGTTTTTTCTGGTTAACCTAAATTTTTATTACTAACACAATGCTGTCGGCTAGCAAATTACCCATTCCAATGGCAATAACGATTCTCACCCGCTTTGTCGTTTGTTTCAGGCAAATCAATGCATACGACCTTCTCGATGAGCATTCCGAACATGCCATTCTGAATATTCTCACACGAGTGAACAAGATCCTGTGCACTCCGGGCGTTCGTAACTCGACACAAGAACACGACGAATAGCTTCATAAAGGTTTCGCCAACGATTGAACTCTTCGAATAAACATTGTATTGAGCACCAATGTTATCGCGGACCACATCCTCGGAGTGCTCGATGGACAGAATCGTCGCCGTCAACTGTAAACCGTACATTGATCCAAGGCTAGTTTTGGAACAAAAGCCGCCCACATGGCTCAAGATCAACCCAGAATTCTCCGAGACGACAACTCGCTGAGCATTCACAAGGATCACTTCGATAGAGAACCGATAGTGCCGCGGGAACTTCGCTGATCTCGCCCAAAGACGTTCGGATAGCAGAAACGGAAGAACGGTGAGAATTGATTCGATGAAGGAGTTTCTAGCGATACATGAAGACCGAGAACTCGCGTGATTTGGAGGGCATATCGGATCTTCCCCTCGCGGAAGATCACTTCGTTCACTGAATGAGTTGAGCAACCAGAGAGGCGCCGATTGTTCGGTTCTGGAACAGGAAATTCACTTGTTAAAAAATATAATATGTTCTTAAAGCTATCACTATTTTTTTGAATAAGAAAAAAAATCACAAAAACTGGAATACACGAAAAAGCAGACAGAAATGTTTTTTCCCGAATCAGTTCCATATTGCAATTTTTAATTTTTTTTTTTCAGAATTAGCGATTTCCTCTTTAAAAAAATTCAGAAGATTCTATTCGATTTTTTCGGAAAAAAACAGGTCGAAAAATTGAAAAAATTCCCAAAAAGTTTGGTGTTTTTTTTCAGTGAAAATCTTTCAATTTATCGGGGTTTGTTTCGACAAAAATAATAAAAACCAGATTAAAATTTTTCAGTTTTTAGTTTTCTTTTCAGAAACATTGAATTTTTTCAATCCGAAAAATTAAAGAAAGGTATATTTTTTGAAAACACAAAAACGGTGGAAAAGTGTTGGTTTTTTGTAAATTTTTGCGTTTTCCAGCAAAATTGCCAATTTTTCCGAAAATTTTCAGATCGAAAAAATATCGATGTTTATTCTCCGAGTTTCAGCGATTTTTTTTGCAGCAAAATTTCAGATACCAAATTTGACATTCAGTTATGTTCCAATTTATGAAAAAAAACTTGAGACCAAAGTGCGGCACGGAAAAATGGGCGCAGGTTGAGTGGTATTTTTCTCTCAAACTAGTCCTTGCCCTGGTGATCACCGTCTCAAAAGTGCGTGTGCAACGAACTCCGCCGGATTTTTCGTCGCCGACTCCTGGCAGACCAACTGGAGCTTGACCGCAATCGCGGCCGCATGCCGAATCGCGTCGTCATCGAGAATCACTGATCCTCAAAATCGCCTTGATATCATCAGCTACGGCGAGTTGCGCTTTGGCATCATTGTCGAACGCGGAGGTTATGAAGAATCGAGGAGACTGGAAGAGAGCCGCGAAGATTTTGTTGGAATCAGCGAGAAGGATCTTTTCAATAGCGTAAGCTGCGGTACTTGTGGAATCGGAGTATTCGAGCTGAGAAGCGCGTCCGCCGACTTGATCGCAATCGGTAAGGTGCTCTGGAGCTGTTTCCTGAAAGTGACCGCAAACTTCAGTGCATCAGCTTTAAGGATCGCAGTCTGATTGAGATCGGTGTTGAGGTGTGTCTTGTGTGATGAAAAAATGAAGTCGTTGATGTCCACCAGCGGGTTCGTCGACGTTACTCCACTCTTAGCAGTCTCCGTCTTCACCGCGATCGCCGTGATCAGCGAGTAGACAATGTCGATCTTGATCCAATCACCACTTGCAGGTTCTGCACTCCCCAGACATGGAAGCCGCCTCGAATCTTCCGACAGAGACCTCGCGCAAGATCGATGGCTCAACGGCGGAGTTCCTACATCGGTACCCTCGATGTCTTGCCGCTTAATATAATCCAGTGGATCAGCCTCGATCAGTTCCATATCCTGTTGACGAAGCAGAAGCTTCTGAACGCACACGTTCTCGAGAGTCTTCAGAACGCTTTCACCAGTGAAGTGTGTAGTACTGTCACTGGCTGACCATCGACAGCAATTCCAGCGCGGCGCACACCATAGTATCGTATCGAGTGTCGGGGCCGGTAGACTTGAGCAGATTCCAGACGGCAAGGAGGATGTCGGGCACGAACGGAGATCTCTCGTTGCGTCGCGAGTAGTGCGCGCAGATCTCACAGATCTCGTGCTTAAGCTCGTCCAGAGTTGTAGGTTCTCCCGAGTTGGAGGTCTGCGTCGGCGCAGTCGATTTGCACGAGATGCAAGAAATGTGGGCATCCAGTGAGACTCATTGATCCTCGAAGGCCTATTCCGGAATCCCTGTGAGCACAGAGAATGGTAGACTTTTGCAATAACTAAGACTCGGAGCCATTGGGCGATCACGTCGGCTCCGAGTTGATCCTTCCGCTGTCTCACCTCCATCATGTTCCGTAGCAACAGAGTAAGAGGCGATCTTGGGGCTGAAAAGGTTCTTTTCATTTGTAGCAAAATCTGGGGACAGGTTTTCGGTCCAAATTCGAGACTGACATTCAGATTTCTTCAATGGCTCACCTAAAAAATTTTGAAAATTTGTCCATTTTTATAGAACGAAAATTATCAATTTTCGCCAATAATTCCTCATTTCAGCGTTGCTTTAGTTATAATTTTTGACTAAAAAATCATAAAATGTTGAATTTTTCACGATTTTTCGGAAAAGGCCAGCTTTAGCTAGCTTACAATGTCTAATTTATTTTTTAGGGTCAAAGCGGACAAAAATTCACGACGGCTGCGACGATTGTAAAAAAGTGGCCCGAAAATAGGGGATTTCGATTAGCTGAGCCAAATTTTGAGCCAAGCAACTCACGCTCTGTAGACACTTCTGCGTTCAGCTCTTTCCAAAGCTCTGCTGACTTGGATTCGAAGCGGAATTTGCGGAAAATCTGCTCCATGCCAGCGGTAGGACACCAGGTGATCGAGATCCGCTCCGTTCAGGCATTTCGACAAATAACCAAATCTGGCCATTTTTAGGGAAAATCTCTCTGAGCGATGTGATACAGAGCATTGGACAGGATGCGTTCCTGAACACTGGATTTTGTATTGAACATCGCTTCGAGAAGCGTGCTTCTGAACTCTGGCTCCTTGTCTTCCGGGCCCATTTCTACCTCTGGTGCCGGGAAACAATTTCTAAATATTCACGGATTTATTCAAATTTTCCAACCCAATTTCTATTCACAAAATATTTCAAAGGGACAGCCGCGGCGATTCGGATCTGTGGAGCTTTGTTGCTGTTTGACCACCAGTTGAAGACTTTGAATGATATAGCGTGGATTTGAATGCAGCGAGCGGAGCGCTTCTTCTCTTGCGTATCGCAGCCTCCGGCTCCAGAGTCTGCTGGAGAGCTGCTTCCCGATTTGCTTCATCGGGCAAAATTACCTAGGGAAAAATAGCTGTTTTGGGGGTGAAATAGGGAAGAATTGGGTAAAGGACAAAGATAGTTTAGCTTAAAACTTGGAATCATATTCCGGTCAAATATTAAAGTTTTACGCAACTTTTCGCACCCGAATAAACTCGCTAAAATTCGCAAAAATAAGAATTTACAAAAGTGTGAAGTGTTTACAGCGCACCCGACCCGACGCGCAAATTTTCTTCAGTATGTTTCCATCGTTTTCACTGATTTTTACTGTTTTTTATCCTAGTTTTCCCTTGATTTTCTTCAAATTTTCCACTTTTTCAGAAACGTGTATTAAAAAATAAAGCGTTAAAACATTTCAATTCCTTCAAAACTTTGCAAAATAAAGGCGTCGTTGCGTACAATGCGCACGACTTGACGCGCAAACTTCCCAATTTTTAGTCTTAAATTTTCCTGGATACCACTGGTTTTTTCTCTGTTTCCCCCTTTTCGCATTTTCAGCAAACATGGGTGTTGATAAAAAGCAAAAGAATAACCAATCCATGCGAGTTAAATTTTAACAAATGCATAGCATGTCGTGAGTTTTTCAGAATTTTGACGAAAAAATCGATTTTGCTCGCAGATTCTCGGCCGGACTAAAAAGGGCGACAAGGAGCACCGACTGCGTCACGAAAACGAGCTCACGAGCAACGTGGACAGACGCTAGGCGTAGAAATGACCGGATAAGATTAGGAAAATTGTCGACAAACGGGTCGGCAGGGAAGCAAAGAGACGGTCTTGAAAAAGCGAGCAACGAGGAGAAGGGCGCGATTAGATTCACAGATGAAAGAGTCAAATGAATTAGAAAAGAGCATCGAAATTCAACTTGACAGATGATGGATATGAGGAGGAAGAAGGTTTATTCTAAATTGAGAAAAATTTTAATAAAGTAAATTTCAGCACTTACTCACAAGGGAAAAGCGCTCTCAGACATTGAAAAATACGACAAATGATTTCCGACTCGGAGATTGAAGAGGCAGGAAATTTGGGCTCAAATATCGTAAAAGTGGCTCTTTTCGGTGGTGGAGAGAAGACCGCCGAGGAGCAGTCCGCGAAAAAATCACCCGAGAGGATATGATTTCGAATTTCATTGCGAAAACGAAGCTGGCGCGTCACGAGAACAGCAGCGTGAAGGATGAGCTCGAGCTGATGACAGAGTCGTTGGATCCCAAGTATCAGGCATGGGCAAAATACCGGAGGCTTCATTTGGGCCGACCGGGCGCCAGCCGTTGACAGAAAAAGATGATTACGACACAAATTGTACGGGAAACATCCCGGTTTTCTCCCCGGCAAATTTTTAAGACAAAAGATAATTATAAATTTAGAGTGAAAATCGATTTTTTTCACAATTTATGAAAAGCTAAAACCCAAAAAACATGATCTGAAAATGCTAATTTCAATTTAACCATTTTTGCGATGGAAGATTAATCGGAAATTTTCATTAATTTTGCTGTAAAAGTTGAAGAAATCCAAGTTTTAGCTCTGTAATCAGAGAAAACACTGTCAAATTATTTCGGAATTTGTGCAATTAAGTGAAAAATAAAAGACATGTAACTAATCGCGAAAGAAATTGAGCTGAACTGAGAATTTTTTTGACGAAAAATCATTAAAAAGTCAATTTTTTTGACAAAAATTCGAGAAAAGTAGGTTTTTCTTTTCACAAAAATGACTGAAAAAGGCAATTTTTAATTTAAAAAAATAAACCCATTTTTCGCCTAAAAATAACTTTAAAGAAAGCCGTCGTTTTTTTACAAAATACAACAATTTAAAATAGCTATGTTTTCGACATAAAAATTAAGAAAAAGCCAATTTGTTTAAAAAATGATAGAAAACGGCTTATTTTTTGTTTCGTACGCCTAAAAAATCAAGCAAATTAGGTTTTATTCCATTTTATATCAAAAAATTATTATTTTTCCCGACAATCACCGTGATAACCGAAGCCGCTCGTGCCACCCCAGCAGATCGTACGCTATCCGAAGAATAATGGAGAAGCTCTGAAAGAAAAAGAACGTGACTCTCGAGGCCGCCCGTTCGATAATGCATTTTTCAACGCATCTGATTTATCATCGCCGATGCCGACGTTGATATCGGACATGCGTTGGATCGAAGGCCGACGCCAGAAAAGTTCAGACGGCGAAAAATGCCAGATTTGAGGTTTGACGATGAAGGTGGCCTGATCGATGAGGATACGGTGGAAAATTCCACGATTTTAAAGAAAAATCTGGATGGTTCTGTTGAATCTGAGGATGACGAGGATCTAGAAGATGAGGAAGAGGATCTGGATGATCTACTGGAAGATGATGATGAGCTGGAAGAGGTGAGATTCCGATGATGTGGAAAGTAAGCCCCAAAGGTCGGCAACATAGCGAAAAAATCTGCTTACCAGAACCCGCTGAACTCTGCCATTCGTATTCGAAATGCCGAAAAACTATACAAAATTCTGAGCTCTTCTGGAAACACAGGAATCGATGGCTATTTAGTGCTGCAACTCGACTCGTGAAATGTCATCATCCGAGCCTTAAAGAAAATAAGAAGCGTCTGAATAAGCTTTTCCTCTTGTGTTTAAGATGGTTTGATATGTGTCGAAGGAGGAATTGACAGCGGAAAGTGTGAAGGAAATGAATTTAGCGCAGGAAACTTATGGGAGGCATGCGTTGTGGTATGAAGGTAGCGATTGGGGCTGGAAAAGCTGAAAAATTACCGCACTTATTAATCTGAAAATTGAAAAAATTCCAGAATTTTTGACCTAACATTATGAAAAATTCCCGATTTTTAAACCCCAAAAATTGCAAAAAAGTCCCGATTTTTTACCAAAAAATGTTTTAAAATCCCCGAATTTTTTACCTAAAATTGAAAAGTTTCGCTATTTAGACCCAAAAATTGCAAAAAAGTCCCGATTTTTACCAAAAAATGTGTTATAATCCCCGACTTTTTGACCTAAAAAATGCAAAAAGTCTCGATTTTTAGACCCAAAAACTGCAAAAAAGTCCCGAATATTGTTACCAAAAAATGTTTTAAACCCCGAATTTTTGACCTAAAAATTGCAAAAAAGCCGGTTTTTTTACAAAGAAATGTTTCAAAATCCCCCGATTTTTTGACCGAAAAATTGCAAAAAAGTCTCGATTTTTAGACCAAAAATTGCAAAAAAGTCCCGAATTTTTTACGAAAAAATGTTTTTAAATCCCCGAATCAATTTTTTGACCTAAAAATTCTGCAAGATAAATTCCAAAAACTTTGGCCAAAAAATTAAAAAAAATACCCGAATGTTTGACCCAAAAATTGAAACAGAAAAAGCCCCGATTTTTTCAGAAAAATCATGTGAAAAAACCTTTTTGAAAATCAGTCTCGAAAAAAAAAAGAAAAACCAGGAAAATCCTGAAAATCAGAAAAAAATCATTAACAAAAACTAGGAAACGATCATGGAAATATTTTTAAAGAAACATTATATAAAAAATCATTAAAATTTCAGAAAAACAATATGGAAAATCCTGATAATAAAGAAAATAAAATGCTCTATTAAAAATTTAAAAAACCAAAAAATTCAACAATTGAAAAACTGCTAATTTCAAATTGTTTTTTGCATTTCGACATTCAATACGGAGTCCGATGTGTGCATGCTCTAATCTGTCAACACTGGAAGCTAGGCCGCCAGGACAACCAGAAGAGTAGCCCAGTGTTGGATTAATCTCTCAATTCGTCTTGTCTACGGCCTCTTCCCAGTTGCCGATTCCTGGCAGCCAGTAGTGGTTCCGGCTCTTTTTTCAACTGAAGCACTTTGCTCGGCGAAATGTGCCAATCTGACTGTGATGCGTTGGCTAAACAAATTCATAAGTTGGCTAATGCTATTCTTGGATTGTGTCTGAATCCAAGAGGTAATACTTGGAAACGAACATTTAAATAGGCAAATTTTGAAAAAAATACTGAAAGCTTTGATATAGAATAGGAAAAGAAACGAAAAAAAAAGCCAAAACCAAAACCCGCAAAAATATTAGTTTCAAAAACTAACGAACCTCAAACCCAAAATAAATTCAGAATTGTTGCTTAAAAAAATCGATTTTTCTCGATGAAAAAAGATCTATAAAAATTCAAAAAAGCAATTTTTTAAAATATAACTTGATTTTTATTTCTGAAGTTAATTTTTTAACAAGTAATTGCATTAACTTTCCATTTTAATGTTAAAAAAAAGCGAATTTTTCAAAAATTGATATTTGTTTTGGCAATTGTTAGATCAGAAAACATTGAAAAATACAAAAACCCCGTTTTGTTTTAAATTAATGGTTTTTTAGAAAAAATTGCAATTTTTCAAAAATCTTGGTCATTCTGTCTCTAATATTAAGTCTCCTCGTCTCTTTGAAAAAACTTTAAAAAACCTCCGAATTATCTAAGCGTATCAAAATTTTTGAAATTAAAAAAAAAACCGTACTCGACATTTTTACGAAAAGTTGAAAATTGTTTTAAATAAAATCAATTTCAGATACGTCCCCGAGCTGGTCTTGCTCGAAGTGCACTTCTGCTTGCAAGTTACAGAGAAAAGTGAGAAATTCGCGACAAATGGATTCCCGATTTCCAAGCCGCACACGGTGTTATGGAGGAGAAGGTAAATTTATAAAATTTGTTTTTTCAATAAAATGTTTTCTTTTGGTTTTCTTTAAGAAGATTTGCTTAAAAACGCTCAATATTTAAAAAACTGGCAAAATCGAATTTTATAATATAAATTAACAATTTTGTTCAAATAAAATTTTTTTTGAAAATTTATTTTTGAAATTTAAAATTTTGAGGAAATTTTCACAAAATTGCCAATGATAAAATGTTTACTTTTTCTTGTATAAAACTGCTTTTTTTTAAAAGCAATCCGAATAATTTTTTAATAGATTGCAGAAAAACCGAAAGACCTCCGTTTGAAAAACGAAAATCAGAGTCAGTTTTTTTCCGAATTTTCTATTTTTCAAATTAAATGTCGATTTTGCAAATACAAAACGGTTAAAAAAAAACTAAAAAAATTGCCGAGAGTCCAAAAAAATATTAGTTTATTTTGAACTTTTTTTTTTAGTAAACACGGCCGCCTTGGCAACGAAGGGGGAGGGATTGCTTGCGCGTTTCGCAATGCGCCTTACGCGTGCTGGCGCACTTCTGAAAGCCTTATTGAATTATTTTTGCGGAAAAAATTCATTTCTTCTATGAAATTTTCTTGAGAAAGCTAAGGAATGATGAAATTTTATAAAATAGTTTTCTCAGTTAAAAGGAGAATACCTTGCTGCAAGAGGTTAAATTTATTGAAAGAGAAAATAAGAAGTTTATCTTTGTTTTGACTACATAAAGTGGGGAAATCGCAAAAAAATTTGAAGACAATTAAGAAATATAATTAAATATTTAATTGCCCGAAAGTAAATAAGAAAGTTTGGTCACAAACAATTTTATTTTTGAATTAGGGAAGTGTTGAGAAATGAGCATGTGCCAGAATCACTAAATCTGAGACATTCAGCCCAATTTCTCTAATTTTCTTTGATTTTATCATGGAAGTGTGGCTTTTTCTGTGGTCTTGCCCGTTTTGTTGAAATTGGAAAATCCCTTGTGAACTGGGAAACTAGCAGTGAAGCTTCCATAAACAAGCCTTACTGCCGGAAAGGAAAGTAGACAATTGGAAAACTAAAACCGAAAGCAAGCATTAAGAAGATCCCGTTTTTATATATTTGATTTGCAAGCATTTTACAGTTTTTTCAAGAATTCAAACTTCTAGATTAAGTTGAGGCACAGAACTCTAAGATGGTAATACTAAGTTTTATGTTGAGAATAGCCAAGAAAGACTATCTGGAAAACATTGCTTTCAATCATTTTTTGTAAGTAATGTAATGTTGAAACTCTTAATAGTTCAGCACTTTGTATGGCTTCCTAATTTGACCCCGAACGTACAGTAGTATGTGGCAAGAAATAAAATATATTGTGCAAATTGGAGCCGAAAAACCCGACCATGATAAAATGTTAAATACGTGTATTGCTCTATTAAAATACCAAATATTAATTAGATTCACTGTCTCGGAACTCTTTTTAATTCAGATTAATTTTTAGCTCCTCTTTTTAACGTAAAATCTGGATTTATAGAGTTCGATCCTGATTTCAACAGGTACATAGACGAATTCTATCTTAAAATGACGAGAAAAGTTTGCTCTATAAACTTTGAGATCCAGGTTATGAGAAAAATAAATAAAAATTTAACTATTTTAAAAAAAAAAATCCGAAAATTCAGCTGTTATTTTCAAACAAATGGTTCGTTATGCATTTCCTCGACCGAACGATTTCCGAGAATTCTTGTTACTTTCGTTTCAGTCTACTTTATGAACACCTTGTTATCATTGATTGAAATAGTAACTAAATCGACGAGTAAAACTAGTAAAAATAGAGGGAAATCACTCTTCAACGGTTCTCGGTGGTGTCGACGCAATGAAGCTGCAGCAAAAAAATTTTGCAATTTCGGTCATTTCAGCTTCAAAAAGGTGTAAAACTTATTAAAAAATTAAATTTCATTTCAAAAAATTAATTAGTCATATGTGCTAAAAAATAAAAATTAGAAAAATTCTAATTTTCAGCGAAATTTCAAATTTATTTTTATTTCAGAAAAGGATTCAAATTTTGGCTTTCAAAACAGCTTACAAAATATTTATTTTTAAAAAATCTAAGAGCTTTCCCATTCTACGGGGGACCCGCACTCCAGCCACTCTCCCTGACCACAATAAACGCTTCAACAATTCCCCATCCGACCAATTACGACTCTATAGAGCTTCACGTTCATCGTGCTCTGCTCTCCCTCATAATCCAACATCTCCGTTTAATCTACGCCAACCAAAATGACTATTCTATCGTTTTCAAGTCATTCCTCCGGATTTTGGAATCAATTCAAGCCAAAAATCTTCAGCCGAGGTCCAGGACTGAGAGCTGGAGACTCTGTGCGTCTCAATGAAGGCTGAAAATGGAGCCGTGCCGTTTCTGGTGCACCTATCGCTGGTGAAAACCGCAAAGAGCATGCTGAAATGCTGGAACCTCGACTGCGTGGGATTTCGATCCGGAACGCCCCCATCACGTACCCAACAAACGAGAAGAAGAACGCTGACGAAGACTCTGAGGAACGAAAGACGTGGAGCCATTACTCAAGGAGAGCTGCTCAGAAAAGGATACTTGGGGCATTCGTGGCCAGGAAGCAATTGTCGAGTGCCAAGACGCTAAGGATCGAGCGAGAATTGCTGTGGCCACGAAACGTGTCATGGGCGGTCTTATGCAGGACAGCATGGGCGAGTGGATTAAGGAGAAGCGTACGGCGGATGTTGAGATTAGAAGAATAAGGATACTTGAAGAATTAATTTAAATTTTCCTATTTTTTGTTTGTTGAGAATGACTTTGGTATCTGGCAAAAAAAACCACTAAATTTCAGTTTTTCTCGATTTGTTGAAAAATACTCATAAAACTGATTTCTATGTTATTTTTGGCAAAATTTGCCTTTCCCCATTCAAACATTTTTTTTGCCATTTTTCCTCCATTATTTTTTTGTTATTTTCTTTTTTTTTCGTTTTTGTTATGAGATATGTTTCTGTTCTGTTGCCATTTTTTATTATTGAAAATTAAACGAGTTTCCTGAATTTTTTTGTTAACCCAATTTTTTTGAAATTTTCCGTTTCACATACGTTTGTCAACCTATCTCGATTAATTTTTGAAGTTTTCCAATTGACTCGCGCATTTTTTAAAAAGTTTTTAAACTGTACATTGACAATTACACCCCTCTAACTCGATCTGATTTTATTCAGATTTTTAGTTTTTTTAGGTGAAAAAGTTCTTGTGCTAAATTCATCCATTATAGTTCGTAATTCAGCAAATTTTGGGTCCGATTAAACTTTGAGCGATTTCCAATTTCATGGGAGTTTCTTGTTCAGAATATGTCTCGAAATTTTCTCATTTCTGGAAATTTTGAGTCTGTCACACAGTGTTCCGTAATTAGCTCGATTTCACTTACATCTCCTCAACTCTGCAAACTCTCAAACTTTCGGAAGGGTCTCGCCATGAAATCACGGGTGGGCGGAATTGCAGTTCGGCAAAGTGCCGGTTTGCCACGGATATTGTCAATCCCGGATTCCGTTTGCCGGAAGTTTTTAAACGGGATCTTTTATAAGACAGACGGAAAGACTTAAAACTGATTTTTAATTTTTTGCCCGTTTTCTCTAAATATTTTCATAGAATTTACTGACTTTTTAGGATAGATGTTTTCATGGGATGTGCACATGTTGTTCCGGCAAATCGGTAACTGCCGAAAAAAAACGACAATCCAAAAAAATCGTTTGCCGTTCTGTATTGTACCCTTTTTGGCGAATGTGCGTAAATTTATATGTGCTTGCGTGTGTAATATTACGTTCATATATTCTAAATATCCGCACCTTTTGAATTACTCATAATCTATGCATTTACGTACCGCGAATATATTTTGGGAATACACATTTATCATCATTCCCACCCGTTGCCATAGTATCCTCATCCCCGCCCCGCCCCGCCCCTTTCTCTCTTTCCTCTTCCAAATCCTTAATGGCTCATCCGGTCATTGGAGAGAGAGATATGGCAGATGTGGCGGTTTTGCCTAAGCAAATGCTCTGGAAAACTCGTATTTTATATAACTATGTAGACAATTTCGATATTAAAAACATTTATATGTAAAATTTTCATTTTTATATGTTGAATTTGCTCGCCGAATTTTGACTTACATTCTGACAATTGTGTGTATTTAAGAGGGTTATGTATATTTACGATATATTTTTAATCAGTTATCGAATGCTCATTTCCGTTTTTCTACGAGTTGTCTTCATTTTCGGTGGTTTTTTTTTGTTTTTTTTTTTTGAAAGTGTATTTTTTAAGTTCAAAAAACTACAAAAATGTTTTCAGTCAGGATCAATTTATTAGGTTTTTTCAATATTAAAAAAGTTATTGGGAAAAATGAAGTGAAACTCGTCGAAAAACGAAAATCATCATTCGATAAAGATTAAATATTTAGTAAATTGACACACATGTAAGTCTCCGCCGCGAAAAATCGATAAATTTCATAGAGGCATAAAAATTCACAATATAGTTTTTTTATTTTTTATTTTAATCCAAATCCCTATGCATGCTTAGTGCGAATTTTTAGCTGTTTTCTGTAAAAAATCAAAATATTGTATATTACATATCATAAATTTTTCCCATTTTCTCAAACGGATCTCGCCACGACAATATTAAAAAATTCCCGTACTTTTCTCCCGCAGGAATGCCGACAACGGAAGAAGCTGCCAAATCGCCGCTTTTCCGACGCAATCGACAATAATGACACTGAAGCAGCGCTGGCACTGCTGAAAACGAAGGAACAGGCCGCTCACGGGATAGTGGAATGAGTGCCTGCTGGCAGCTACTTGCCGCGTATAGGTATGCACTTTAAAGCGGCGACGGTTACTTTGGATCCTCGCAGATTGTTTAAAGGTACATACCGTAATCCATTGAATTTCAGAGGAAATCTTACGTTGGTCGAGAAAGCGATTGAGCTGAAATGTGAATGAGAAAACCGATGGAACTCTGTACACTCCACTCATGTTTGCCGCCAGGTAGGCAAAAATTTTTTAAAAAAATTCCGGATTTTGCGTCAAATTTGATGCAAATTCTGGTTTTTTTTCCGATGATTAAAGTAAAAAAAAATTCCGAAAAAAATCGGATTTTTATGCTAACAACTAACTTTTAAATGAAAAATCGTGGAAAATTACAAATCACGTAGTTTTGATCTCAAATTCAATTTAACGAAAAGTCAAATTTTATGGTTTTCGCGGTGACCAATATTCGCCAATTTTTTTTTGCCCCAAATACAACACATTTGACGCGCAATTTCATTTGAAACTTTTTCCCGTTTTTACACTCTTTTTAGACTGAACCCCAATATTTGAAGGCGTAAAAAAACAAATAGGACCAATACACTATATCTTACGCGCAAATGTTAAATTTTTATTTAAAATCCTCGTAAAGTTCTATGTTTCTTTTTTTGATCGTTTTCAAGCTCAAATCAAGTTTCAATCCGAAATATTACCGGAACATAATAAATGCGTACTGGTCAACATATTTGACGCGCAAAATATCTCGCGTACAGTAATTCATTAAATGACTACGGTAACGCTTGTGTCGATTTACGGGCTCGTTATTAAAAATCATTTTTCAAAAAAATCGAGCCCGTAAATCACCACAAGCGCTACCGTAGTCATATAATGAATTTTACCACTGTAGTTTTCTATAGGCGAGATATTTTGCGCGTCAAATATAATACACAATCTCAGGACTAATTTTGCGTTAACGTATTACTCTACTTTCTTAGTTTTTCCAAAAAAAAAATTCGAATACACCATATTTAGACGCGCAAACTTTTTTTTACGTTCAAAGCAAAATTGTCAAACGTTTGCAGGAAAACAGGCACGTATGCCGCCTGAATGGACTCCGCAGCCCGTATGTATTTGGTGAATGGAATCGGAAAAACCGCCTCTGAACTGGCGGAGGCATTTGTGGGTCATCACGAGTGTGTGGCAATTATCAATAATCATATAACAATTGATGTGATCGAAGATCTTTTGCGGCCAAAAGTGAATGGAAAATATTATCGAATGAGCTGAGGAATAATGAGCTGGCTGTATTTATTCATTCCTTGTGTGGATCACATGAGATTCATCCTGTTAAAATTATTTTTCGATTCAGTAAATATCCAGCAATTCGTTGAAGTACAAGAAAAAGGTACATAGCTGTGTAGTTTGGAAAAAAAATGAAAAATCTGAAAATTTGAGAAATTTCCTTAAGCTTTTTCAAGATGCGCATTTTTGTTCATTTTTATTTTCAAAAGAAATCCAAAAAGTTTGTTAAAAAATTTAATGAGCATTCTTTTTAATTTCAAAACAAAAAAGTTATACCAAATAAAAACTTTTAGTAATCAAAATTTTTTTTCTCGGTTTTTCTCATCGTTTTTCAAATTTGAGATCTCTTCCCGAATTTTGCCTAAAAATTGATTTTTTCAAAATAAGAACTGATTCTGTGAAAAAATGTATGAAAATGCGAATCGCAAATATTCGAAACTAAAAAAACTTTTATTAAAATAAATTTTTGAAATTTTTCAGAATTTAAAAATTGAATCGAATTAGGTCTCAGTTCAGATCACGATTTTTTCGAAGTTCTGAATCTGTTAAAAACGAGAAATTAAAAAAAAATTTGATGTTAAATGTTTTTCGAGATTAAAACCGAATTGACAACCCAAAGAAAGTGTATCATGTAAAATGTTTTTGTTATAATAAACCAGAATTTTCTCGAAATTTTCAGAAAGTTCTAGAATATTTCAGAATTTTAGGCTCTCGAAATTTCCAAAAGGTTCTAGAACATTTTCAGAATTTTCTCGAGATTCATTTTTCAGAGGGTTCTAGAACATTCCAGAATTTTCTCGAAATTTTGGTTAGAAGATAGTAGTTCAGAATTTTCTCGAAATTACCAAAAGGTTCTAGAACAGTACATAATTTTCTCTGAAATTTCCAGAAGGTTCTAGAACATGCCAGAATTTTCTCGAAATTTTCAGAAGGTTTTAGTATATTTCAGAATTTTCTCGAAATTTCCAATCGTAAAGGTTCTAGAACATTTCAGAATTTTCACGATTTTCAGAAGGTTTTAGAATATTTCAGTAGCAATTTTCTCGAAATTTCCAAAAGGTTCTCAGAACATTACAGAATTTTCTCGAAATTTCCAAAAGGTTCTAGAACATTACAGAAATTTCTCGAAATTTTTAGAAGGGTTCTAGAATATCTCAGAGTTTTCTCGAAATCTCCAAAAGGTTCTAGAACAATCCAGAATAATGTTTTCAAAAAATTCAAATTTGTCCCGCCAAAATGTTTGCAAGAAATTAAACTTCGAATTGCCAAAATATGTACAGTACTCCTACAGTACCTCTACAGTACTACTACGGTACACCGAACGTCCCATATCCCACTACTAACCTAACCTATATCTCTTCAAAAGACTAGAACACAATTTTTCCTAAACTACAGTAATCCTACCGTACTCCTAAAGTACTACTACAGTACCCCCACCATACTCCACTGCTAACCCCAAACCTATATAATCATCAAAAAAACACAATTTTTCCTAAACTAGAGTAATCCTACCGTACTCCTACAGTACTGCCCTACGGTACTACTACAGTACCCCCACCATATCCCACTACTAAGCCCAAACTAATATCCTCCATCAGCCAAAAATGCCTTGCCCCAAGTTTGTAAACAATGAGGTCTCTAGTTGATTAACAAACGGACACTATTTTTTTATTTTTTTCAAAGCAAAAACCATCCATTTTCCAGATCCTCTATGTCATGGGTATCGTGTCTTCGAGAAACAGCTTCGATGTAGGGCAAGCAATGAAATAATGTCGCTCAAGCTTTGGCTAATTCTATTTTCAAGGCGTGAAACCTCGAAATTTGTGGAGTCGAACAAGGAAAAGTCGCCAGTAGTACAACCAGGTACGCAAAACTGAGTTCCACGTGGCAAGAGGTTGGCGATGAAACTAGGCGAGCACATGAACCCGCGTGATGAGAAATACGGTTGCATGCGTACGTTCCCTAACAGTATAAACATTCATTACTTCATGATACTCTACAAAAAGCACTGCAAAAAAGTCAAATTGGTGCGAACGATACACCCAATGTGCCACGTATGAATACATTGTTCAGGCACTTTTCCGACAACGAATCGCTGCCGTCTGCCCGTTTTGCTCGGGGGTCTTTGCGGACATCGGAGCCAAGAAACGGTGCTCACAGTGCAAGTAGGGAGTTTTGTGCTAGGGTTAAAAATAATTATTTAATAATTTAATAAAGCTCGAATTTGTGGAAATAATCAATCTCCAAATTTTAAAAATATGTAAAAAATTTTATTCCGTTATATGCTATTTTATAAATTTTCCCACAAACTCGGCATTTGGCTCTAGCTTCTTGCTTTAGCCCAAATAATATTAACTTGAAGCTGTCTAAACACGTTGGGAAAAGTTAGACAAAGACTTTGGCAAAACTTGGATTCAGCTTTACCAAGGTCTAACCCAAGTTTCACCCAACTCTTGCCAAACTTTGGCCCAAAGTTTTCTTATTTCGTTTCAAATTTGGGCCAAAGTTAGGGAAGAGTTGGGTGAAACTTGGGTTAGACTTTGGTATAGCGTGAAGCCACGTTAAAGTCTTGCCTAACTTCCCAAGTTTAGACAGCTTCTGATCCAAGTTAACATTTTTTGGGCTAAACTTGGGTAAGAAGCAAGAGCCAAATGCCGAGGAAATCCCGCCGAAAATTGAAAGTTCAAAATTTCAGCTTCGTTTTTAATTATTCTGCAAAATTTGGAAGTTCCAACAATTGTTTAAAGATTCTTTAAATTAAAAAAAAGAATTATTAAAACTTTTTAAACACCAAAATTCATTGTAGAAAATTCCGAGCGTAAAATACTCTTTGAAAATCCGGGATAAAATCAAAAAAAAAATAAATTCTAGACATTCTGCCATTAAATATCGAAAAAAGAACATGTTGTCTGTAAATGTATTAGTCAAAATTAATTCTGTTTTTCCAATCAAAATTTTAAGTGTCTGTAGAGACTTATTTGAGTTTCCTGTTTTTCCTCGTATTACTAAAGTTTTCTATAATATGCTGTGTTTGAAAATTAACTATATGTGAAAATATCGAGGCACAACGTTTTCAAGATCTGGTGAAATTTCGGATCTACGTTTTTCGGATCTACCATTTCCGGATCTACGTCTACCGGATCTGGCACCGTGCCAACGCGCAAAACGCTTTTTTGATCACTCGGCGCACGTTGTTTTTTGTAAATTTCTTCTAGAAGAAACGCTTAACCACACGCGACGCGTAACAACGGAGCATCGTTATCACGTTTTTCTCCGAGATTAAAATCTTCGAGCGTTTTATCAAGAGTCACGGTGCAAGACGAAAATGGTAGATACCTCGGGAAAACGGAGATCCGGAATTCCGCCAGATCTTGAGTGGTGCCTCAAAATATCGATTAATGAATTTTTTCCGAAAACCAATTTAGCTTCAACAACAGAATAGCTAAAAAGTGATCAAGAAAAACTCAATTCTTATAAATTGCAAACACTTTCCAAATTTTGATAAAATGGAAAAGATTTTAAAAATTTCAGGCAACACATTTTTTAACTCTAATAAACGTTTTTTAAATTCCAACAATTTTTACAGCTCGCCTACTGTTCCCAAAAAGAATGCCAAAAATGCGACTGGCCAATTCATCTCAAAAAAGTGTGCTCATTTCTGAAGAATTAACGCTACAAGAAGTGTCGCCCACCGACGAGACCGCCATGGCGCTGGACTCGGCTCAAATCGTGGCGCCAAAATCGAAGTGTAGAAGTGCCGATATTCGATCTCAATATACTTTTTTTCTGGTAAATTTATTTATTTTTATATTTCGGCTTCATCTCATTTCACGCAATTTTAATTTCATTTTCATAGATTCATTTTTGAAGTCATTCCTTGAACAGGAAAATTCACTAAAACATGCATTAAGAAATATGGAATCCAAAAATTAATCTAAAAACCTTTTCAAAAAACCACTTCGTCAAAAACTGATGATGGAAAACTCGTTGACAAAAACGGAAAGAGTATCCAATAAAGATTAAAAAGTTCGACATTTCGTAAATCGACACAAATCTCGTCGACAAAATCAATACCGAAAAAATCAGGAACCCAAGAAATTCAATATTCCCATTTGTAAAGACAACTCGTAAAACATTTTCAAATCAAGAAATTATTTTTTTTGCCCTCAAAATTGATCCTGAGTGAATACTATAAAAAAGAAAACTATAAAAAGTGGCGAAAATTCGAAATTTTAGCCCCTCTAAATTGGTTCACTTTAGTTGTCTAATGATACAACAAAGTAGACATAGGTTACAATATCTGATATTGGACTTGTCTAAACAAAAGTGTTTTCGTTTTTTTAACGGATTTTTAAAATCCAGAAGAGTAACGAAAAAAAATTATTTTAAGAGAATAGAGTAAACTATAATCATGTTCGAGAATCAAATCCGCCTAAGAATATGAGGTACGGACCCAAGTGTATCATAATTATTTAATTTCTGTGTATCAGAATTATTTTAGTTTCCTTACTGTGATAGGTTCCCAAACTGCTTAAATTTAGGAAATATTTCTTTACTGGACACTCTTAGCCACTGTACGCTGCCGATCCCAACGCATAATAAGAGAATACAGAACACCAATTATGCCCGAGAAAAAGATACTCAGAATATAAATATAATTTATCGGATGGATCGGCAAACATTGAAGACACTTTCTAATTACCCAAATTGTTCAGTATATTCTAAATCTAATTCTCTTAAACTAGAACCCTCTTGGCCAATGTACGCGGACGAACGTATCATAAGTAAATACAGAACACCAATTATGCCCGAGAAAAAGATTAGCACTCAATAAACATTAGTCAAATTCGGATGTATAATGATTCCCGAAGACACTTTCCAACCCACATTGTTCATATTCTAAATGAAATTCTTTTACTAGAATTGTCCAATGTGTGCTCCGAACGTATCATAAGGTGAATACAGAACAACAATTATGCCCGAGAAAAAGATCACTCAGAAAATAAACATAGTTGAATTTATTGGATGTATAAAGATTCCCGAAGACACTTTCCAATTACCCAAATTGTTCATATTCTAAATGAAATTCTCATACTAGAACACTCTTGGCATGTACGCAGCCGAAGGTATCATAAGTGAATACCAGAACACCAATATATGCCCGAGAAAAAGATCCTACTCAGAATATAAACATAGTCGAATTTATCGGATGTATAAAGATTCCCGAAGACAGTTTCGAATTACCCTAATTGTTCATATACTAAATGACAATTCGCTTACTAGAACACTCTTGCCAATGTACGCAGGCGAACGTATGTGAATACAGAACACTAATTATGCCCGAGTAATCCTACTCAGAATATAAACATAGTTAAATTTTGGATGTATAAAGATTCCCGAAGGCACTCTCCAATTTACCCAAATTGCTCATATTCTAAATGAAATTCTCTTACCACTCTTGGCCAATGTGCGTGACGCGGCCGAACGTCTTTTATGATAAGTGAATACAGAACACCAATTATGCCGAGAAAAAGATCCTACTCAGAATATCAATTAAACATATTCAAATTCAGCGGATGCATAAGGATTCCCGACTCTTTCCATACCCAAATCATTCTAATTGAAATATCTCTTACTAGAACACTCTTTATTGGCCTATGTACGCAGCCGATAACGTATCATAAGTGAATACAGAACACCAATTATGCCCGAGAAAAAGATCCTGCTCAGAATATAAACATATTCGAATTTAACGGATGTATGATTCCCGAAGACACTCAATTACCCTAAATTGTTCATATTTTAAATGAATCTTACTAGAACATTCTTGGGCCAATGTACGCATTGCCGAACGTATCATAAGTGAAAACAGTACACCAATTATGCCCGGGAAAAGATCCTACGCAGAATACAAACTTATTCGAATTTATCGGATGTATAAAACAAGGATTCCCGAATACACTTTCCAATTACTCAAATTGTTATTCTAAATGAAATTCTCTTACTAGAACACTCGGCTTGGCCAATGTACGGAGCCGAACATAAGTGAATACAGAACACCAATTATGCCCGAGAAAAAGATCCTACTCAGAATATAAACATAGTAAAATTCTGATGTATAAAGATTCCCGAAGACACTTTCCAATTACCCAAATTGTTCATATTCTAAATGAAATTCTCTTACTTGTCTAGAACACTCTTGGCCAATGTACGCTGCCTAACGTAACATAAATGAATACAGAACCCCAGTTATGCCCTAGAAAAAGATCCAACTCAGAATAAAAACATATTAGAATTTACCGGATGTATAAAGATTCCCGAAGACACTTGCCTTTCCAATTAACCAACTTGTTATTCTGACTGAAATTCTCTTACTAGAACACTCTTGGCCAATGTACGCAGCCGAACGTATCATAAGTGAATACAACAAGAACACCAATTATGACCCGAGAAAAAGAGCTTACGCAGAATATAAACATAGTCGAATTTATCGAATGTGATTCCCGAAGACACTTAATTACCCAAATTGTTCATATTCCAAATGAAATTCTCTTACTAGAACACTCTTGGCCAAGCAGCCGAACGTATCATAAGTAAGGAATACCGAACACCGATTACGCCCGAGAAATAGATCCTACTCACTCGAATATAAACATATTCGAATTTAACGGATGTATAAAGTCCCGAAGCACACTTTCCAATTACCAAAATTGTTCATATTCAAAATGAAATTCTCTTACTAGCACTCTTGGCCAATGTACGCAGACGTATCATAAGTGAATACAGAACACCAAATATGCCCGGGAGATAGATCCTACTCAGAATACAAACATATTCGAATTTATCGGATGTATAATGATTCCCGAAGACACTTTCTTACCCAAATTGTTAATCTTCTAAATGAAATTCTCTTACTCGCACACTGCCAATGTACGCAGCCGAACGTATCATAAGTGAATAACAACAATTTACCCGAGAAAAAGATCCAACTCAGAGTATACACATATTCGAATTTGATCAATCGGATGTATAAAGATTCCCGAAGACACTTTCCAATTAACCCAAATTGTGCATATTCTAAATGAAATTCTCTTACTAGAACACTCTTAGCCAATGTACGCAGCCGAACGTATCATAAGTGATTACAGAACACTAATCATGATCGAGCAAAAAGATCAGATCCAGAATATAAACGTATTCGAATTTATAGGATGTATAAAGATTCCCTATTGGGAAGTCGAGCAATCCACGGCTGGTTTATCGGCCACAGTCCGCGGTTAGGACATGGCTTATATTATTGGGCCAAGCGGAGCACCACCAGGCTGTGTACCTGACTTCCAGATCAGCAGTACATAGCACTAAGAAAGGATCGTCCTTTATATCTTTTAACCTTTTAAAAAGAATCGAAGGAACTCTCAGGGTCATGTGGTTCTGGGGACAAAGAGGGAGGCTTACATCAATACCAAACACTGGTAGATAACAATACCTGTGGTAGATCACAAGCCACCCTAGCCACAAAGAAAATCTGTGGACGTCCTCAAAGGAGGCCGCCGGCGCCCTTGAGCTGGCCAACAAACCCTTCGAGCAGGGTGGAGGACTACTCCAGCGACTGAAAACGGCGGTATTAACGCCACGTTGTCGCCCAATAACAAAAAGCCCTCGGGAGAACCTCAAGAAGCCCACGGCTTAATTTTCAAATCAATTACCTTACTATGAATCTCCTTTTGGCTCTACGAGTCGTCGTTGATGTTACCATCCATTCCGTCCTACCTGGGTCCCGTCAAACAGTCCATCTGACGTCCAACCAACATGGGTGGAGTGTCCAACGCATCTGAAATTGAAAAGTATTTATATCCACTGATTTTTTAAATGGAACCATTTACAAACAAAAACGGAAACGCTTAGGTAACCAAAAAAAAAAACAATTAGTATTTAAAACAACGGAGACAAATGCTCTCGCGTAAGTTATATTAATTTTCCAGTCGACTGCAAGGCATCTGCTCCCACGGGTTTATATAAAATTATGTACCTATTTTTCTTGAAGTCGACTTGTCTTGAAATCTTTCAATCAGTACTTTTCAAGAGTTTTTGGTAATTTTGTCCGTCGATTTTTCAGAAATTTCAAAAAAACGGCGAAATTCCAGTCAGAAGCCTCATTAATATATCACTAGTCCAGCTCGCTGACCCAAAAAATTATTTTTTTTGAACTACAGTAATCCGACAAAATTGCTACAGTACTATTACGGGACAGCCACATAACAAACTTTTGAAAAATGCGTATTGCGCAACATATATGACGCGCAGGCGCAAATATCATGTGTAACGAAAACTACAGTAATAATGTATGACTACTGTAGCGTTTCTGTCGATTTACGGGCTCAATTCTAATCGTAATGTTACACGACACATTTTCGCCAAATGCAAAAAGGTGTGCGCCTTCAGATTAAAAAAAAGTTGATTTTTGTGCCGGCTTTTAACACATCGAGAAAATAAAAGAAACGAAAGTTTGTAATTACAGTACTCTTCTTAAACGCGAACACCTTTTCGCTTTTCAGAAAAACTTGCGCCGTTTCGAAACCTGGTACTATACTTTTATAATTAAATCGATTAAAAATAAATTTTGCGGTGGAGCATAAGTCATCAACTCGAAAAGAAAAAATCTTGCATGCGGTAAAAAAAAAGCAGCAGTACTCCAAATCACCCATTGGAGAATGGCTGGAAATTGAAATCAAGTCTGCACTTTGAAAAAATGCAGCGTTGAATGAGAGAGGGACAAATCGAACAGCATTTTATAAGGAGTCCAAAAAAAATGTTTGTGGTAGGTCTTGAATCGTGCAACTCATCGTTTTAAAATCAATTTTTAACACTTTTATATCATAAAAGAATAGTCTTTCATCATCAATCGATTAAAATACCAACTCTCGAAAATTAACAGCTTTGTTAACAGCGCCGTCTACCTGATTTGAAATTGCTCGCAATCGGTGCCGCTCAACTAAATGTTTTGCGCGTCACTTAAAATGCGCCCTTGTACGTTTCAGAAGCGCGTCTCCTAAAAAATAAAAAGGCTAGTCCAATTTTATTAAACGGGTATTTAATTCATGTAAATATATGAGCTGCAAATTTAGGAAATCTAGGTTTAACCTATCAAAAACTATAAAGTGGCAAAAATGGGCAATTTATGGCAACAATTCACGATCTTGAATCTAAAGGGTTCATTATTATTGGTAAAAGAGGACTAAGAAATTGATATCCGAACCCTAAAAAAATTGTTTTTCAATATTCAGAAGATATTATGAAGTTAGTGTACTTCCATTTTTTCGATTGTACGGTAAATCAAAACTAAAGGTGGGCACGGGCGTATGATAAAGTTACGATCGTTCCAATCACCAAAGTCGCATAATCACAGCCAGAGCCTCACATGAAAACCCAGTGTGTGGGAAATTTAAAAATCAGTACAAGAAAGCCTCAAAAAAAAAACAAAATTACAGGAAAAAACGGAAATTTTCAGTAAAAAATTATAGGGTATGTACAATCGATAAAAAATTTATTGAAATTCAATCGAATTCTCCGTTTGCGGCGTTCGGATCGTTCACTGAGGAAGAGTAGTACGGGATGTCGAAGTTTGAAATTGAAGAATTCGCACCAACCGGACCCCTGGAAGTAGATCGTAGGAGCTGCAAAAAATGTTCGTGGCCGCGAAAAAAATCGGTGGCCGATTTTTGTTTTTTCGGGGCCACGATGTGACTAGTCGGCGAAATTAAAATTTGTTTTTTGGTAGTGTTCAAAACTGTTGTTCTGGTTGAAATTTTATCGAATTTTTTTTTGTGGTTTTTTCAACTAATTTTTTTTTCTGAAAATACTTTTAGAACAGTTCATTTTTTTTTCAATTTTGTTCAGACCCTTACTCCCTATCATAAAGCCTCGGAAAATCGGAATCCCATCCCTGAAACTCGTGAGAACCGTTCTAGCGTGTACTTCGACGGAGGCCGGTGAATATCCAGTAGGTCTCGTTTTGGACGACGGCTTCAAGGACACGACCGAACAGTGAAAAAGTTTTATTTATCAAAACCATTTTTTTGAGGAAAAAATTTATTGAAATGTTTTTTTTTTAATTTTAAAATTCCAAAAAAACGCAAAAGGGCAAAAAAACTTGAAAAAAATGTTCATTATTCCGACTCACAATCAAAGATAATGTGTATCAAAAAAAATTAATTGTTTTCTTTTAAAAATTAAGGAACTTATTTTTCTAATGGTTATTTCAAAAAAAGTTAAAAATAAATTTTTCAAGTGTTTTTCAAGAAAAAATTAAAAAATTTCGAAATTTCCGGCAAATTTTAATATACTTTTTATTTTGCCAGGGAAAATTTGTATAAAGCTCCGCATTATATGGATTTTTTGTATTGAATAATAAAAAATTTTTTTATTGGAAAAAATGATTTTTATAGTTTTTTTTTGTTAATTTGAAAAAATTTTATCACGGCAACTCAAAATTCTGAGAATGCGTACTGCCCAATATATTTGACGCGCAAAATATCTCGTAGCGAGACGACAGTAATTCAGAATGACTACTGTAGCGCTTGTGTCGATTTACGGGTTCATTATTTAAATGACTTTTTCGTATTATTTCTAATTCTTCATTTAAATTAATTTTAAAAATTGAGCCCATAAATCGACGGTACCGTAGTCATGTTCAGGAATTACTGTAGTTTTCGCTACGAGATACTTTGCGCGTCAAATATGTTGTGTAGAACGCATTTACAGAATTTTGAGCTGCCGTGATAGAATTCGCATTTTTCAAATTAAAAAAAAATTTAGTCAAAAAAATCACGATTTATTTTTGCAAAAAAATTTGTCTAATTTATAAAAAAAAATAAAAATAAAAATTGAGCAACGCTGAGAAATCGGGCCAGATTTTTTTTTGTTATTCTTTGAAAAAAAAAACTTTTGTTGGAATTTTAAATTACATAATTTATTTGGTTCAATCAATTTTTTGGTTAAAAAGCGTTTTTTTTTCATTCAAAAAAGCCCCTCAAACATGTGCCTTCTCTCCTTGTTCGGCTACGGCCTAACTAGCATCTCATCAGGAATTTTTTTCCGCCTGGCTTCTCCATCAAATACCACACACTTCCCACTTGAATTTCCCGGGCTCAGTGCCATGCAAGCCGATCCAGCTTGATTCCGAACTTCTCAGCATAGCCGGTCACAGGATGCATAAAATGTTTAGCAATATGAATTCGGAAGGATTCATCGTCCGATTCCGTCTCATCAGGCGAAATAATTAAAAAAGTCCAGGCGTTTTGCATATGTTTCGAATTGTTGAGACGCAAAATGACTGGCGTAGGTCAGAATGCTGAGTGGATCCAAAAGTTCAAATTTGTGGCCGACTTTTAATTTAAATTTGCAACAATTTTTCAGCTGAAATGTGGTTTCCCAGCAAAAAGTTGCTCGAAAGTGACGTCATCTTAATGATAACTTCCAGAACCTTCTGCGATCCGTCTGGAGATGTTCGAAATAACCTTCCGTAGCCTTAGTCCGCACCATAATCAATTAAGCATCATTGCAAGAATCCGACTGGAAAGAGGAAGAAGCTCGACTCATTCTACCCATCAAAACTCGACTTTTTCAGGCTGAACCTGCCGATCTTTGGCCTCTACGGAGATCTTCGGGATAATCGAGCGGTGACCATGACCTTCAGACGGCGGCCAAGGATAGGATCCATGCGACACGGATTTCTGGCTCCGAGTACTTGAGTCGCTCGCTTGATTCAGCCGGAAAAGGGCAGTGGGCAGTCAGGAGGCGGAGTTGGTCGAAGATTTTTGGATCATCATCAGAGATTCGATTTTCGTGCAGCCCGGCCTTGCCTGCCGGAAAATTTTTTTAGGTAATAGGAAAATCAGAAGGGTTTTTTGGAGTTTTTATTCAGTACACCTTATTTTTTTTGTTGTTTTTTTGAGGGTTATAAGTTTTTAGGTAAATTTTTTTTGTTGATATTCTTGGTTTGTTTAAGAATAAATCATTTAAGTTAGACAAAAATTCGTTTTTAAATATATTTTCGGTTTTTTGCTGGTTTAGTTAAAAGTTTTGTTTTCGGATTTTCATTTTGATAAAAATTGAAGCCTTTTTTTTTTGGTGTCTTTCTTAGGTTTACGAGTTTTTTTTTTGGTTTTTGACGAAAAATTTCTTTTAAAAAAAACGGACTTTTTAAAAATATGGGTTTTCTTAAAAAAATAAATTTCAATTTTTTTTGTTGGATAAAAAACTGTTAAAGTTTCTTTTATGGCTGAATTTTCGCCTTTTTTCACATTCTCCACCAGAAAGAACATGAAAAAAAACATAAATGAGTAAATGTTTTGAGTATTCAGGCAGTTTTTCCGCTCAGAAAATAATTTTGGCCGGATTTTCATGGTTTCTTACATTCAGAATCTCCTCTCTGCTGTTGGCCGTGGTACGGGCGGTGCAGGCGTAGATCCGCGTCGACAAAATTTCGGGCATGGTCGGTGTCAGCAAGCTCAGTGGCCTGTATTGAAGCTCAGCCATTTCATGGATCCTTGAGACCGCTGAAATTTCGCGTTTTTTTTTGGAGATTTTGTTGAAATAACCTTCCAATATGAATCGAAAATATTTCCCTCTGAAAGCATATGAAACCAGCAGGGTCTTCTAGTTCCCCCACAGGCGAATTTAATTGCCACGTAGAAGCCGCAGACAGCAGTCGCTTCGCCGAAACAGCCAGGATTCAGTTCTGGAGATTTAGTGGTTATAGTCCAGAGACGGTCGGACGACTACTTCTAGCTGAAAACATTAATCCAGATTATGGCTTTAAAGTTTTTTAACAGAAAAACCAACTCGAAATCTAGGTTTTAGGTGCTGATTTAGCTTTTCCAGCTAGGCAAACAACCCTCCAGCGCCTCGACAGGTAAAAATTGACTATTTCCATCATAATTACAACGGAGTTCATCTGTCCATGTGAAAGTTCCTTCAATTTGTGGCTTTGGAATCCGCTATCTCAGATTTCATCTGTTCGACGATACTGGAATAGCCGTTCTGATGTGAAATATCGGTAGTCTGCTTCATCAAGTTTGTAATTATATTGACGCTGAAAGTACTAAATTATGTTTTTTCGATAAAAATGCTTTGAAAAAATACGGAAGCTTTTTATTCGAATAATTCAATTGATTTAAATTAAACATCTATTTAAATTGTTTAAATTAAAAAGTTCCACTTCTGTACTTATCACGTCGAGACCCAACACATACCAAATGGGCCTTTATATAAATTTTAAGAAACTCAACATTTTACAAGAGTTTTACAGTTTTTTTGTCGTTAAATCGTTTTTCGAAAATAAATGATTTATACTCACAGTTAACTTGCTTCGTGCGCAACTTGAATATTAGCTTAAATTTCACAGTCTATGGGTTAAATTTCAAGTCCGACTGATGATACGGGAGGTGCGTGGAAGTACGGTAGTTTGTTTTGTTTTTTTTTATTTTGCCGCCGAGTGATTCAAAATTGAATTTATATCATCCGATTTTTTGATTTTTTCTCAATACTTCTCGATTTTTCAGGAATCTTTCAGTGTGATTTTCCAACCGTAGCTCGACCCCAGACGAAGAAAGCCTGAGGCTGGTCGCCAGAAGCACTATGAATTGCGGTTTTTGATTTAAAGCATAATTTGCATTAATCTTCTAATATTTTAGCCACCCCACACCGTCCACGAACAAACTCCGAAACGAAGCTCGGGGCTCGCGAGCAGCTTCTCCGGGACTCTATACGAGTGGGTTTAAGTTCTTAATTTCATAGAATATCACTTATTCAAAAATTTTATTTTTTCGCTTCAAGCAGCTTCGGAGCCGTACGTCCACATGACAAAGGAATCCACGTGGGACGAGGCGAAAAAACTGGCTCTACGATCAGTCTAAAAGAAGCCGGACATTGTCCGTAAAGCGATATACAATCGTCGTCGCTTCAGGGAGTCAATGAAAGGATAAAAAGTTCGCTGGTCAATAGCGCGAAATCATCGACCCAAGAAGCCCGGCAATCAAATGCAGTGCGGCGGAGGTATTTTAAAAGAAGACAAATTAATATCTAATTATTCCCTTTAATCTTTCAGACAATTGCCATAAACGTTGTGCACTGCTTGGAGACTCATCACACAAAAATACTCGCTCAGAAATCAAAGCGGCCCCGCTGCTCGGGAGCCAGCGCCCAGCACTGCATGGAGCGAATTAATTCAAATTAATATTTTACAATAAACTCATTGCTCGTTTCACACATAATCATTCATGTGTTTTTCACTCTCGAAACCCATATACCCCACTCTAAATATCTATATAATGCCACATTTCTCATAGTTTTAATCTGCCCTTACCAATTAAATCTTGTCCCACCTATTTTCCGCCATGATCCCTTTTTCCATTTTGAATAAAATACGACGACGATTTTTCCTCCATTAAACCAAGGAGAATTATATAAATAGAGTCAAAAGTGGCGCTTGTGTCGCTCAGCGGTCTCCTCCACTTGCAAGCACTATCTCACCGCGGCCTTCCAATTTCTCGTCCATTTCAGCTGTAACAAGTAGTTTATAAAAACTGAAAAAAATGCAAGTTTTAGCAGAAAATCGCTGAAAATGGCAAATCGTCGAGCTAAAGTCGCTTTTGACTTCGGAGCCAATTAAAGCCATCGAGTTCTTCGATAGGCTCGTTGGACAAGGTTTGAGCCGAAAATCAAAACATTTAAGCTGAGATTTCTTTTAAAAATATCCCTTGCAGATGCCGACACAATCATCCAAGAAGCCTGTGGTGACAACCCTCGCCACCTATATCCGGCATCCCTATAAGTGTTTTTAAGCGACGGCTTCTGTGAGCTCCTAATCGTTTTTTGCGAAATTGTGCATTTCGTTTCAATTTCACAGCTTTGAAGACAAAGTTTTGCGGCGAAAATTGATTGAGCATTCGAACGATTCAGCGTGTTTTGCGGTTAACTGGAAAAGGACAAGCCACATGGGGTTTCGTTTATTGAAAATTGAAAAGATTTTTGCAAAAAATTAGATTTCATGTAGTTCAAACTAAACGCTGCTCGATTTTTAACCGAACCTTTTTCTTTTTTCCGTGAAAATATCGGTTTTCCAAGTTTTTCGAACATTTTCCAAAAAAAAATTACGTAAAATGTGAAAACGATTTTCAAGTAGCCTACAAATCCGGAAAAATCAAACTTAAATGTTTTCGAAAAATTTCATAATTTTCTTCAAATCTCTTTGAAAAGTAGATTCCACTTCTGGGAAATTTGAATTTATGTCATTTCTTTAAAAGCGCATGCTCTTTTGTAGGGTCTCGCAACGAATTATTCAATTTAAACTTTTCGATATTCGCGCCGAAATTTGGGTCTCGGCGCGATTTAAAATAAATGAAGAATATGGACTATTAATTTTTCCTTGAAAATTATTGATTTTTCGGAACACCGGCACCACGTCACCGCTGTCGGATCGAATCGTTTCTTCATTTTGACTACTTTCCGATGGCAGCCCCGTCTAAGAACCCCGACTGGTCCCCGTGCCACGTGTAATGAAATCAAATCGAGATGACAAATACACACACAATATTTTTGACTGCTGAAAATCAGATTTAAGGCTGCGGAACAGCTTCATCTTTTTTGCCGGCTAAAACGGAGAGCTGAGACGGACGGTGGTTATGTGGCACTGCCCACTTTGGTAGAATTCCAAAAGTTACTGGATACGTGGCAGATGTGAAGGTGTTCGAGGAACAGTTTTTGATTGGCGACAAAGCCCTCTACGGTTCTAGAAAATTGGTGGCGGAGTATTTTCTCGCGGCCACATGACTATTTTCTAAACGAAAAGTTGTGTAAAAGACAAGTCGGAAAGGGCGCCCTCATGGCTGTAGCTGAAACGTTTTTCATAGATTTTTTGGCTTTAAAAAAATCCTTAAAGGTGCATTTTCGTGTCGAGAATCCTAGTTGTATAATTTTGCTAATTTTGCTTAAAAATCTTGTACAGTACCAGGTCTCGACGCACACGAATAGTTTTGATAAATGCAAAAATGTATGCGCCTTTAAGGATGTAGTAAAAAATAAGAATTCCTTAAATTTGATAATTTTGTGAAGAAAAATAGAAGAATAATTCTTTGAAAATGGATAATTTTTTGGAAAAATTAGCTTTGTTTTTTATTTTTTCTAGACGTACACCTTTGTTAAAAGATTGTCGCGCCGAGACCTGATACCGTATTTCTTGAGCGCAAGATCGTGCCGAGACCCAAATTCGTGAAATCTGTCAGTTGGTAGGTGTGGAAAATTTCGATTTCCGGGGAAACGCGACGAATCTCGTCGAATTCTAGCTTTTTGTTCTGGTAGAGGAGGAAAACGAGGAGAAATTGGAGAAAATGACGACAAAATATCGATTTTTACGTGGCAAATGTGCCGATTGAGGAAAGGATTGTGAAGGCGGTTTTTTTTCTAAATTGAAAACAAAAAAACTAAAAAAATAAAATTTTAATCGTAGTTTCTAGAATTCAAGCCAGTTATAATAATTTTTAAACTAAAAATTGCATCGGTTCCGAACTTTCAAGGTTTTTTTTTCTGAAAATCGTTTAAAAAAATATCTGCTTGAAAAATCAAAATTTCAAAAAAACAAACAAAACTTGAAAAAAAAAAACGTCTTTAGCGGTATTTTTTCTATAATTTTTCAATTTTTTCAGCGATCCTTAAGAATCGAAAATCGTAATTTGACTTCTTCCTGGTATATCCAAAAATGGACCAAGATTCTGTGGGATAAAACGAGCGATTTCTCAGCGGAAAAGCCGTTTCCTTCATAACCAGTGGATTTCCAAAAATGGCAATTTTCGAATCATTTCAACTTTTAAAGGAACTATTTATGGCTGATCGAGAAATTGACTTTGCACAGGAAAATTGGAGCTATGCGGAAGAACAAAGATGACGGGGTGTTTGTGAAAAGCGGAACTGTTTTGGAGCATTTTGACACAAAATATACACTTAGTGCACTGATGGAAGTGGTCCCCGGTACTATTGGAACAACACAGAGTGTTTTTCAAAGTTTCACCAGATGGGCAGATTGATTATGAAGTTTCGTTTTGTTTGGAATTTGAAGGAATTCGACCTTAAAAATATAAAAAATTGCACTGATGATGATTATGGATTTTTTTTTCAGAAAAAACGAAAAACGAAAAAATTGAATGCTAAATGACAGAGTCAAATATGCCCCTGTAACTTTTTTTTTTTGAACTAAATTTTATATTATTTTTTTCAGTTTTACGCAAATCAAAGAAACGGGTCCACCGAATTAAATTTGAATTCCCGCGCACCAAAGAGTGACGTCATTTTTTTTTTCCCGATTTCCTGATGTGTTATTAGGTTTTTATAACGGTTTGTCAATTTTTGCAGACATTTTTTTTTAAGCTTGGTAACCCGAAAAAAGTGGCCTAGAAATCGGCTTTAATTTTTTTTTTAAATCGACAAACTGTGTTTCAAATTACGAAACAAGGAAAAAACGAAGAAGAAAACAGCCGGAAAACGCGAAAATCTCGAATGACGTAAATTGCGCGGGAAAAACTTTAGAATTTTTTTTTAATTAACAGCTCTAACATAGGGTCGAATCATCCTAGGGCTTTTGTCAAAAACCTTATTCCTCGCACAAATTGATTTTTCGTTTTCGTAGTTTTCACATGGAACAATCGAAAAATTTTGTTTCTCAAAAAAAACAAAAAATTTTTATTAAAAAATTATTTTAATCCCAAAAAAAAATATTTAGCAAACTTTAAAAATTCATAAAACATTTAAAAAAATTTTTTAAAAATTGTATTGGGACTTTATTCTAATACTTGGACTAAAAAAAACCCACATTTGACAAAAAATTCAATTTAAAATGAATATATCGTTTTGGGATACCAAAACGAACAGAAAACCGAGAGATTCGAATTCGAGTCTCCCAAAATTCACAAAATCATCAAAAATGGTGACAATGTGATCCAGTTGATATGTTAGACGCGACTATTCATATTCATCAAAATTATAGACTAATCAAGACGTATTGAAATTTCAATCGAATCGATTATTATTTGGATCTAGCCGAGTTATTTGTTTCAAACCGATGAGATGTTTTTCAACTGAACAAGAGACTGTATTTGCTGTGGATTTGGAGAATTTGGAATTGTGGAGGGTTTCTTTTATTAATTAAAATTTTTTTAAGTGGAAAAATTTTGGTTTCTCTTTTCAGAAATTATTATAATGTTGTAACTAAATATTACGGGAACACGAAATTCTAAGAATGCGTATTGCACATACACAATCGATTTGACACGCAAAATAGTAGCGAAAACTACAGTACTTCCTTTAATTACTGTAGCGATCGTGTCGCTTTACAAGCTCAATTCTTTTTAATACTTTAAATTAAAACTTTTTCTTTAAATTTTAAAAAAATTCGACTTATTTTTTAATTTTTACTTTATGCCAATATTCTGTCGATAAATAAATCATTTTAATAATTAGAAAATTGAGCCCGTAAATCGACATGCGTGAATCCATTTAAAGAATGTAGTTTTCGCTACGAGATTTGTACTCCTAATTGCGCGTCATATATGTTGCGCCGTACGCACCGTTCTCAGAGATTTGTGTTCATATAGAATATTAGGACTAGTATGTTAAAATTTTTAAAAAGTTTGTTTCGACTTTTACCCAAAGATCTTTTTTTGCAAATTTTTAGTGAAAATTATTATTTTTTACAATTCCGCACGCTAAAATTTATTAAAATTATATTTAATTTAGACTGTATTCTATACAATCAAAAAACAACAAACATCAATAATGAATGTTCAATGAGTTTAAAGAAAAATTTTTTTGTGTAGACTTTTTTAAAACTCTTCTTCGTTGACAAAACGTTCACAAAACTTAAAATATCTTTCAATTTGCTTAAATATTAACAAAGAATTTTTAAAATTTTTCAGCCCGAAATACCAACCTATATCACCAGAGGAATTCGTTCCCACCGACACTTCTCCCTCCGATATCTGGTATTTCAAATCCCGAAATTGAAATTCCCTTCTCACAAGTACCCTCTCCTACTACATTCACGTCAAATTGGAGCTCCAGAGATTTCATTCAAATAATGGGAATTTCGATATGTAAGGATGGTAAATCAGAAAATGAAGTGGAAATTGAAGCGAATGCAGTGTTGAAACTGTGAAAAATGCGCTGAGAGTGATGCTCAATATTCGACCTCTTCTCAAAATTAAGACTATTGAGGTAATTGGATATTTGGTGAAATTTGAAATGAAAAAATATTTATAAAAATTGAATTTTTTTTCATTATTTCAGTCACCATAAGTCAATAGCCGTTTCCATTAACTTAGATAAAAATTGATATTTTCTTTTTCCAAATGCGATAAAAATTGGAAATTCTATAAATTCCGGAAAAATCGATTGATTACAACAAAATCGATAATTTCCGGAAAATTGATAAATTCCAGAAAATCGGTAATTTCCGGTGTAAAAGTCGATAATTACCGGCAAAACCAATTAATTTCCAGAAAAATCGGTAACCCTTACCGGAAAAATCGATTGATTATCTACAAAAGTCAATAATTTCCGGAAAATTATGATAATATCAGAAAAATCATTAAATGATCGATAAATTCCAAGCAAAACAAAATCGATAATATCCTGACAAGTGAATAAATTCCTAAAAATTGAGGAATTTCATAAATTCCCGGCCTTGAATATTTTTTAAATTTAATCTTTAAAAGAATAATTCTTTAAATCTTTAATCCTTATCTAATTTATTCAAAAAAAAACTGATCCACAAAATTTTTTTTTTTCAAAAATTAAATATTTTTGCCTAGTTAATGTTTCATCAACTTGATTATCATTTACTCGAGAAATGTTCAATGATTCAATGCATTCTAATGGAAACAGCCATCACTGAATTCACACTTCCATTTCTCTACGAATTATTCTGTCGTATTCGGGTTATGAGGACAAAGTGTTGGATGGACTTTTGCCGAGGAAATCTTTGATCATTTATAACAACTCGATTTCCAGTGTTTTACCGCCAAATTCTTTGTACGGTAAGTGAGTTAAGAAATGGAAAAAAACACATTTTTGCTACTGTTGGAATTTTTTTTCTAAATTTCACAAATATCTTATTTTCCATTTTAAAAGTAGAAGTTTATTTGCTGGATTTCATATCAATTTTTAAATATTTTGATTTTCCAGTGCGGAATTTCTGTGTTTTTTGAAGCAGGAAAAAAACCACAGAAAACTAACTAAAAGAATTAGCAAAAATGAAAAACATACGTAAAACGATGTAACTTGTCCACGCCACGTGTAGTACAAAAAACCGATGTGCACCAACAAATTTTTGCAAAAGCTATTTTTCCATTCAAAACGGCGCCCCAACAGTTGAAATTTTATAGACGAAAATTTGCGAAACTGTTCGCTTCTCCGAAAATAAAAGTCTCAGATCCCATTCTTGGGTCTTCCAGATAATCGTTGAACTCCAAACTGGAGACCGGTTGCCGCCGACACCAGGAGCACATTAACAGTTCCGTCGAAATTCAAAAATCTAGAAAATCTGAGCACCTATGAGCCCCAGGACATTGTCAAATATTTTCTGAATCTCGACCAAGAGTCGGAGGATGTGACATGGCGATCGATACGTCACGAATTCCACGACACACTTGACACGTGGCACGCGGAAGCTGTGAAGAAGAGAGACGAGAGACGTAGGAGCAACACGGAGCAGAAAGAGTAGTATTCGTAAGGAGAGCTTTACGAAAATTCAAAAGGCTTCGATGACGGCATCGCCGGTAGGAATATCGATTTTTATGTATCGAGGAATTTACTGGAAAACAAAGTTTAGGAAAAATGTCGATTTTCCAGAAATTTATCGATTTTCCTGAAATTCGATTTACCTGAAATTTATCGATTTCCACCCTGAAATTTATCGATTCTGGAAATTATCGAGTTTTCTGGAATTTATCGATTTTCCTGTTTTTTCTGGAATTCGATTCTTCTGGAATTTTTCGATTTTTCTAGAATTTCCACAATCGATTTTTCTGGATTTTATCGATTTTACTGAAATTTATCGATTTTTCTGGTATTTTTCTGGAATGTATCGATTTTTCTGGAATTTATCGATTTTTCTGGAAATTCGATTTTTCATATATCGATTTTCCTGAAATTTATCGATTATTCTGGAATTCATCGATTTTCCTGACATAACAGATTTATCAATTTCTGGAATTTATCGATTTTTCGAATTTATCGATTATTCTGGAATTTATCGATATTTCTGGAATTTATCGATTCTTCTGGAATCGATTTGTCTGGAATTCATCGATTCTTCTGGAATTCAGTTTTTCGAGATTAATCGATATAATTGTCTGTAAATTTTACTCCCCAAAAAACAATATATCGTGCCGAGACACGAAAAACTCTAAAGAATTACAGATTCCAATCGGGGCGGCCGCTCGAGTAGAACCCGAAAGTTTCTAAAAATCAATCAATAGTCCTGTCATTCGCCACTCAAGCTCTCCCTCACCAATCAAAGGAATGCCAGAGGTAATCGTCGAGAACCAGCACGCCCCCTGAGCATTTAAATTCCACGTTGTAGTCCCTGAGCCACGATAGTATTTCCAATTCACTGGACGCCGAAATGAACATTTCACCGTCACCCTCGACACCGAAATCCTCTTCCTGTGGCGGAAGGTCGCATCGCACACCAAAAGCGATTTAAAAAGTGATTTCGAAATTCCGAGGTCGTGAAACCTTCCCAGTCACCACAGAATCCTGGGTGGAAAATGGGCGGAGCTTCCGCGTCGATTCGCGAAGAAATTGATCCGCAGGAGATACGCGACGAAGTTGTGAAGAAGGAACAGAAATTGCAGACTAACGTGCGTCATTTGAAATTTTTGAAAAATCGATAATTTTCAAAAAAATCGACTTTTTTTGGAAATTATCGCTTATTCTTGAAAATTATCGATTATTTTAAAAAATTATCCTCGAATTTTCTGAAAAGGATCTGTTTTCGGGCAAAAAGTTCCGAAAGTGTTTTCTCGAAAAACAACGACTTTTTTTTTGAAAGTTATCGATTAAAGAAATGTCATCTATTTCTTTGGTATTTATCGATTTATCTTAAGAAATTATCGATTTAAATATTTTAAGGAAATTATCGATTTTTTTAAGGAAATTTTCGATTTTTATTTATCGACGTTTTTTTTAGGAAAAAGTTTCGAATTTTCTCGAAAAATAACGACTTTTTAATAAAATTTATCGATAAGAATCTATGTTTTTTGAAATTATCGATTTTTTTTGAAAATCATCGAAAATATTTTAAGGAAATTATCGATTTTTTTGGAATTAATCGATTTTTTAGGTAATTATAGGCCGTTTTTTTTCAAATTTATCGAGTTTTTTAGGAAATTATCGATGTTTTCTGAAAATTATCCCTCGATTTCTTACAAAGGAAAAGTATCGATTCTTGGAAATTATCGATTTTTAAGCAAGTCTCTTATCGATTTTTCAAACGAAGAGTAAGGAAAATTTTTTGAAACTATCCATTTTTCTTTATTGATTTTTTTCCTAAGAAAATATCCATTTGTCGATGGCTAAAAATGTGGATTTTTCTGAAAATAATCGATATTCTGTTTGGAAATAAAATATCGATTATTTCTAAAAAAAATTATCGATTTGTGCAGGAAATTCTCGATTTTTAAAATAAAAACAGCGATTTCTTTTTTGAAAATCGATTTTTAGGGAGATTATCGCATTTTTCTGATTATCGATTATTTCTTCAAAATTATCGATTTTTAGAAGAAAAGTATGGATTTTTAGATATAATCTATTTTTAATTATTGATTTTTTCACCTGAAAAAATATCGATTTTCTGAAACAACATATAATACCACACATTAATTTCAGGAACCGGAGTTCAAAAAAGTGCAGCTTCTACCACACGTGGAGACGGAAGAGCTCGACGGAGCTCAAACTTTGGAGGTTTTTCGACGAGAAAGGAATTCACGATGAGGCGTTCATACGCTTGTGTAGGAACTTGTGATGGTTTTTCTCTCAAAAATTTGAAATTCTTCAGTTGGAACTGGTGTTTGATGCGACGATTTGGAGGGGAGTTGGAAAACGAGCAGATCATCTGGGGAAACATGCCGGGACTTGTTCGACGTTAAATTTTCAATTTTTGAATTTTTTTTCTCTTGTAACTTGCATTTTTCGTTTAACTTAGTGTTTTCGGTGTTTTTTGGACTATTGAAATATTCGGGTTGTTAATATTCAAAAATTAATTACATTATTAATAATAAATGCATTTTGAAATGGTATAAATTGAAAATTTTCAAAAAACCCCCAACCCAGTGGTTTAGGATGAAAATCGTGGAAAAGCCGAACGAGAGAGTTCCGAGTTGGCCACGTGGGACTGAAGCCTAATTGAGTGAATTTAATTTTGGATAAAAAAATTTTGGAGATCTCTTCGACATTTTCTCAAAAAATGATCCATAGCTTTTTCCCATTTTTTTGTTGCTTCATTTTCAAGCTCTTCGGTTATATCGCAGACGTTGAAGCAAGGGCCTTCCGGGAGAATTTCCTGAACATTTGAAGCGCCTTTTTGGGTGAACAAAAGCAGCTTAAAGGCATTTTTTGGTATTTTCAAATAATATCGGAAATCTGCGTTTAAATTTTTTTTTTAAAATGAATTTTTTCAAATAGGTTTTCGAAAAATCGAAAAAAAAATTTTCGGGTTTCCGGTGGAAATTTTAATTAAATTATGTGTTTATGATGATGAGAATAGTTGACAATAATTTTTTCCGATTTGTCAACACGTTTTTCAAAAAATTTGTCAATATAATTTTTTCCATTTTTATTCCTGAACAGAAAAAAATCGAAAAATTTTCGGTTTTAATAATATTTCGGAAAAATTTTGAATTTACCGTAGTTGTGTGATCGTTAAAGAAACTCACAATATTTCTAATCGAAGTATGCATATTTTTTAAATGAATTTTTGGAAAAATTTCAAACTTATTTTTTGTTGAATTTTTCGTTTTCTTTCGTTTTTTTAAACAGAACCAAATTTTTCACCATCTTTTCTTCAAAACAAAACAAAAAAAACCAATTTTTGTTTTTTGAAAAGCGAGAAAAATTTCGAAAAATTATTTTAAAAGTTAGAAAAATATCAATTTTGAACGGAATTTTTTCAAAATTCGATTTTTTTTTTTTCTAATATGTTCGAGAGTTTGTCGCCATTTTTATTTTTAAAAAAGGCTTTCAAACTACAAATTTTAAATGAGAATTTAGATTTTTTTAACGAGTAATGTTGAATATTGGAGAAAAAATAAATCAATTTTAAATAGAAAAGTTTTCTTATTCGTAACATTTTCAGTGTTCTCAAAATACAAAAAACTCGTACATCCTCCTGACAAGTACAGTAATCCATTGGATCCCTCCTGTCCAACACCGTCGCTTCCCGAATGTGAACCAATTGTTCATTTTCATAAGAACCGAGCTCACAGTCAATTTCCCGACCATATTTCCCTCGTATTCCTTCGAAAATGGCTGAAGCCCGATTCAAATTTCAAATATCACGGTGGTGGAGAGAATACGGACAATAGATCCGTAATTGATTTAACTTTAAAATTTTTTTCATTGTCATAATCATGCTACGTGGTCTGGACATGATCTGTTAAATTCTCTCGTTTCGGCGGAGAATATAATCGATATTCCAGTGGCACGAGGTTGTCGAGAAATCTATTAAAATTCTGATAATATCGTTCCAATCTCATTTCGAAGCTCGTCAGTTTCGGCTTCAGCTTTTGAAGCCAGTCGTTTTCAGATTGTGCTCCAGCGCGTCTGAGCTCTGAAAGTTTGATTTCAAGCAAAATTTTGTGTAAATGATTCAGACAACCCCATTTTTCATCTAATTCGAAATTAGCCACATCTAGAAATTAACCACATTGACTAATTAGAAAATTTTCTAATTAGAAAGGATGAATATCTAATTAGAAACGCTGCACAACACATCTAATTCGAAGGGATGCCTCGTCGAATTAGAAATGACATCGAATTAGAAAGGTGGCGCGTTGAATTAGAAGTTACGCGTCTAATTAGAAAGGAGGCACATATAATTAGAAACATATTGCGCACGTCCACATCTAACTAGAAGGGATGCTCGTCGCATAGTACTACCTTTTAATGTATGTACTACCTTTTAATGTATGTACTACCTTTTAATGTATGTACTACCTTTTAATGTAAGTACTACCGTTTAATGTATGTAGTACCTTTTAATGTCTGTACTATTCTAATGTATGTACTACCTTTTAATGTAAGTACTACCTTTTAATGTATTACCTTTTGGCTCTTTGGAAATATATCGATCAAGAAACAATGCCGAATTAGAAAAAAGGCATGAACTGGTGCGCGTTAGTTGACCTTTTTTTCTAATTAGATGAGAGGAATATGGTAGTCAAGACTGCAAATTATCAAAATTTTTTGGTTCAATTTGTTTTTGAAAAAAGTGAAAATTCCTGGGTTGCAATTTGTCGATCAGTATTACGTAGACGTCGAAATATGCGATTCGCCATTGCGGTCTTAGGGGTCTCGCCACGCCGACAATCAATGTAGTTCATGTCGATTTACCACTGTTGCATCGTAATATTCCAACAAATTTGCCGCCGAGGTGAAAAAATTCAATAAAAGCCCGTAAATCGACATGAACTGCAATAGGGTTGTCGGCGTGACGAGACCCAATTCTCATCTTTCGTACCGACGTCCACGTGATATAGAACTTTTTTTTTTGAAAAAATACGATTTTGCCTAAAAAAAAAACTGTAAATTCAACAAATCCCACAAAAAAAAAGCGAAAAGAAAAAAGCATCGCGGAAGACAGTGGCGCCAGGCTGTCTCAATACTGTTTGATCTACAAAAAATGCGGGAATTTTTTTCACAGACAAAAATTGTGACGTCAGCACGTTCTTAATCATACCGAAAATGAGATTTCTGCCTCTGCCATCCCGCATTTTTCCAAGATCAAAGTGGAAGGACTTTCACCTGAATAGGACTTTCTGATTCCACGTGGGAAGGAAGAGAAATCCAAAATTGCGATATTTCACTAATTTCCCTGCTTGAATTTCCTTCCAATCAGCGTCTTCAAACTCCGCGGCCCACTCCATCTGTGGATGAAAAATGGGCGGCGCAAATCGCTCTGATTGGTGGCAGTTCTTATTGCCCAATCATTCAAGTTCAATATCTGGATTTTTCATTTTTGACCACCTCCAATTTCAAGCTTCTTCCTTACCTTCAAATCGTAGAATATTGCCGATTCTCTCGGATTGATTCCTTCCTTCAAAACCAGAACATCTTTCAACTCGAACCCCGAAAGCAGATATTTTTTAACCTGAATTCTCCTAGAATATCCTTCGCTCGTAGCAACTCTCCAACGATTCCTTCTGTTTGTAGAAACTCTTGTAGAGTGTACACTGCCTCGTCCAGATCTTCGCAAGATGCCCGTAATTCGATCTTCCGAGCTAGTCAAAATTGCATATGTTGGTGTTTTTCGTTTCGAGCAACACATGCCAATGAGGATATAATCCGAAGTTAGACTCGTTGTTGTTAAAACGCTTTATAATGCTGGCGAAGATTTCCTCGAATTTCGTTTTTCTTTCTTGAAATTTTATCAGTCTGTATAGTTTTGAGGGTACAATAAAATCTCGGGACAACTTTTCGATATCTATCATCATCGTCATGTTATAGAAACCTATATACTACAGTGTTTTTTGAAGAGTTTACACCACGATACGGATTTTGATCGGTTTTTGATGATCAATTTGACTAATACGCTCGTCTCCGCAACGTCTTAATCGGTCCTAATGCAAGGCTGTGCGTTGTGTACAAGTGCCTTGCTTAGCTCTTCAAAACCGGAGCGATACATAGACACGAATCGTTTCATGCGCAGCGCAGCTGCTCAGGGCTCTCGAAAGTTTTCAGACATTCCGTGAAGCTCTCAACAATGCTGTTGAGGTTATCCTTTGGCACATTTTCCCGAATTTGATTAACTTGTGATAGATATTTATCTGATATATTCGATATTTTTATGATATTTTTCCGTGTTGTTTAGGATGTTTTGCCATCGCAAATTCAAATTCCACATAGTATTCCAAAAACTTATTCAATGGATGCAGGAAGTGAATTGATCCTTTGGCAGAAACGCTTTATATCCAATAATTGCTCTGCACTTTTATCGTCGAATAATTTCTTCACGTTAGATTAGGGAGCCCTAGAGATCCACGAAGTATCAATTCGTTTTTGGGAAGGAATAATTCAAAAATACCCAAAAGAAAATAGCCTGATGGCCTGGAAGAAAGCCGTCCGAGGATTGAATACAACGAATAACGTCCCTGACCTTTCGCACCCAATTTGAAAGCCCCAGTGTCGTATTGGTGTCGCGAATAATTTCTAAATCAAACGCCCCTTCGAAATTGTGTCCCACTGACAAGAAGTCTCGAACACTTTTACTCGCTTCATTTTTCATTATAGTCGTAGCGGGTTCGAGATAAAATGGAGATCTTGAGCAATGCGAATACTTTCTTGGCTCGTTCCGGAAGCTAAGAAATTTCTGTAGTAGGCGCCAACCTCTTCGTCCGTTTCATATTTCCGATCTGTACGATCATTAAAACGGCAGAAATCTGGGGAATATTTCTAAATAACTCCAACTTTGCTCCTCAATTATCCATGTGAAAAAATTCAACCCGGATTTTGAATTTCGGCTTGAAATTGCCGAATTCCCTTGGTGCACACATGCAAATTTTTCAAACGCGCGGCCCAAAAATTATTATCCTTGGAGCGCGTTTGCCTGCTCATTTGATTCTCTCCCGGAGCACGGTAGCTCAGAAACTAGATGGATGCTGGTTCATTCTAGATACTCAGTCTGGATATATTGGCTACTATCTCGACCCGGAAACCATCCACATAAAATCGATCTTTGCGATGCAAATAAGAAATGACCGCAATGAAATTATCTATCTCCATTCGTGATGAATTTTCGATTTTGTACTTCCTGGCCAAGTTTATGCACGTTTGTTCGGAGCGCGTTTTCACCCATCTAGCAACTGACGGTTCAGTAGCCAATATAGGTTTCACTGTATCATGAACCACTCCATCTAGTTGCTGTGCTACCCTCGTGCTGAACCACCGTGCTCCATCTACCGATTTCTTCCATTACGATATGGCTGCAATACTATTTTTTGATGGTCTTCCCGCTTGGTCAATACTAATAGGGAGTGCAATACTAATTTTCAGAACATTTTTCTGCCTTTGAGACTAGTTTTTTTCTGAAAAAACTCGAATTTTATGTAAAAATTCAGTCCAAAATTTGTTTTGATTGTAACCTATTTCAAAAATTAATCTCGTAGAAATTTATTTGAAAAATTGCTGCAAAATATGCAAAAAATATTGTAGAAGTCCTAAAATTAGCGAGAGGGGATTGCAATAAAAAAAGTAAACGAAACACTATTAGGGAGTTCAAGACTAATAGGTGCCAGACTAATTTTCCGCAGGTCTCCGAGGGGCAATACTAATAGGGAGTGCAAATCTAATAGGGAGGCCATGCATACTAATAGAAGAAATACGGTATTTTTAGTTCCTTTATTTTGTCAACGAGAAGAATCAAATGAGGGCACCAAACGCGCTGCAATAATACTATAATTTATTGTGCGCGCAAAAAAACTCATTCGGCACGCAAAGAATATTCACGAATTTATGCTGAAATATAATATCAGTTTTTATGTTTTTTTTTAACATCCAGATATTCTGAAACAGAGGAATTTTTTTTAGTTATTTGACAATATTTCCTAGATTTCGGAAATCATGTAAACAGCAGCTTTTGTACAACAGCTTTTTTTTAACTGTGAAACTTGTTTAAAAAGTCAAACCACGTCCATTTTGAAAATTAATTTTTAACATATAAAATAAAAACATGTGGAAGGCTTTTGATTCATGTACATACAAGTTTTGAAAAATACGGCATTTAAATTTGAAAAATGTGTTTGCTAAAATCTGATCAATTTTTTTGTTATTATCTATTAATAGCTGGACTTTACTTTTAGACAAAAATTACTCTAATTAAAATCTACCTTCAAACCATTTTTTCAGTTTTTGCAAATTCTCCTCGGAAATCAGTAGGACTAGCGATCGAGTGGCAAGTGAAAATCACGGAAATTTTTCAGGCGATTTTTCAGGCCCCATGTTGCCACGCCAACCATATTTTGGTTTCATGAGAGATCGGAGCTCATGAAATAAATGCAAAGCAAAAATCCAGCGAGGTGGTGATCTTTTAGTCATTCTCGCTGTACTTGAAGATGTGGGAGCTTCTTTAGTAAAATTTACAGCATTCTTCTCTATCCTTATAAACATGTTAGTCATTAGTGTTCTTTTTTCCCGACAATCTCCTTTCGAAAGCTCTCTGCTCATCCCATCCCCCAATAGCTTTTTTTTTGTAGAAACTTGAAATCCTATCAAAATCTATCCCGATCAGCTGATTCGTCAGATCCGTAGAAGCGATTTCGCCTCTGAGAAGCCCAGCGACGATACGATAGCAGTAACACAGGAGCGGTGGTAGCAGGTGAGCTCATCCAGTGAATCCGTTCGACAGGTTTATAGAGTACTTTCCGTAGAATTACTGAAATTATATTTACTATTAAAGTAGAAAAAAATGATTATATAAACTAACTATACGCAGGAAGACTCGCATTATGTTCCAGATTTCGACCTAAGAATTGTGGATGGCGTCCAGCCGGAAATTTTTATTTAAATTTAGTAAATCCTTTAGTGAAGAAAGTTTTTTAATAAATACCTGTCAAGCGCTTACCCTTAATGTGCTCCAACATTTGAATACCTTGCCGCTCCCTTTCCGAAATTTCGAGATCTCCGCATCAGCGTTTACCCGGTAACAAGAAGTAAGGGAATTATCGTTATAATCATCTTTATCTGGGAAAAAATTAATTTTCATGGAATATATTTCAAATTTTCGACAACCAAAAAAATTCACATTTTTTTCAGGAAATTTCGTTGAAAAATCTGTTTTTCATAATATTTTGAGAATAAAACAAGCGTAAAGGTATTCAAGAGCGCATGCAATTCACTTAAGCCAGGGTGACCCTCTAAGCGAACATAAAACATACGGTATTTAAAAATATTCTTGTTTTCCGCGGAAAGTCGGAGAATTTAATTTGATTTTTTTTAAAAAAAAAGAAAATTAACCGTTATACGTTTTGAGCAAAAAATTCTACAATAATAATTTAAAAAAATTAATTGAATAAACATTGAAAATAAAAGTGCTTAAATTTCAAGGCGCTGCGCGTGCATCAACCGTCACTTTTGTTTGGGTATCACCCCAGCACCCCGAATGTAAAAAGTACCAGGGTAAGAGTGCGCGCTTTTTTTCATTTTTCGAATTTGTGCGACCAGTTCTCATTATTTGAACGATTTTTGCGGTAATTTTGGACAGCCATTTTTTCTAGTTCCCACCGACAAATTGCATTATATCCGTAATTTCAAGAAAATTTTGTTATAAAACCAACAAAAATCTAGAAAATTGCTGAATCATTTTGCGTATGAATGGTCAGGCGGATCTGCTCGCTGCGACCGAACCGCCTATCGGGTCTTCAGCCGACAATCTCTACGACATAGAACTGTTCGAGGTGTTCAATCGTGTCGCTAACGTCGTCACAGAAAAGGCGTTCTATGGAGCCGCCCGATCACGCTCTCGGATCATTTGTTTTCAAGTTGGCATTTTTTTTCAAATCATTTGTCCTCACCTAAATCTCTAATTTTCCTATTTTCAGAATTCAAGGCCTGTATCAAGCTCGTAAACTTTCAAGGAACAACTCTTCACGGCCGTGCTGCACATTCGTCCACTGCGAGAAAGTTCGCACGCGAACAGCGAGGCCATCTCAACGATGTTCGAGAAGGTCAAACATAAGGGAAATTCCGGGAATTCTTCGTAGCGTCCAGAGCACTCGTTCCCCGAGTACCGAAACCAGAACCCACAGGCTTCATCATACCTTCCAGTCCACGTGGTCATCGTCGACGGGCAGTCTCAATGGTGGCGGCGGGGGCTATCGACGCCGACGTTCCGCCGGTGGCAATCAGTACAATCAGAACAAGTATCCGAACGAAAGGTACCAGGGATGACTCGATAATCATCCAGTGCAGCAGTATTCGGGCTTCAATCCCAGCGATTTTTGCTGTGATGACTATGTGGAAGGAGCCGAAAAGGTGCAAAATTCGCCAAATTTCGCTAAAAGAAATTTCGCCGACTTTTCCCGTAGCGCAACAGTTTTTTCTTTTAGGCACATTTCAGGCATTTTGGGCATATCAATATTTTTCCACCAGATATGTTCTAGATTTAGATGGACTAGATTTTATTCTCAGACGAATCAAGTGATTTTCTATATTTTTACACTATTTTTTCTTGAAATATGACCATAAAATGCAACAAAGTCTTCAGCAGCTGATGGGAAAAGGAAAAATCGGCGAAATTTCGAATTTCAGTCTATTTAATATGTTTAAGCAAAAAGAAAACTAATTGTTGAATTTCAGACTCGACAACCTTGCCAACCTGATTCGCTGGAGCACCTCCACGGATCCGTTCGCAACCTAATTATCAAAAGTAATTTTGAATTATTTTGAAAATCAATAAATTGTTTGTTTTCAGACGTGAATGCACAAGCACATCTTGTTCTCGTACGAATTGAGCTAAAGATCAAAAGCATGGCCCGCCAACGTGGAAAATGGAGCTGCAGATTAAGAAAGATGACCACCACCACTAGGGCCGGCGGCGGAGCAGCAACCACAGGACAGAACAGACTGACCCCACAACAGTTTTTGGCTCAGATAGCTCAGAGACAACAATCGGAGCAAAACGCGGATGAGGTGGCCAAGAAGAAGCGTCCGAACCTTTCGGGTATCAATCCAGCGCTTTTCTACATGAGCAATACCCGAGAACATCGCCAGTTGTTTATGCTTAAAATCTATAGAGTAATATGGAGATTTTGGGAAAAAAACATATTTTCTCGAAAATACGCCCGAAATAGTGTTTGTAAATTGGCGAGACCTATTTCTTCTGAAAAATTATAATTTTTTCGATTTTCACGTGAACTTGCAGGTTTTTGGATATTTTTCTCGAAAAACGTCAATTCATCGATTTACGCTAGTATACTCAGCAATCGACCCATTTTTTCGCAGACAATTTGGTATTTTTCTTAACTTGATTTTTATTCGACTTCTCGTGTAATCACTTATTCAAATGCGCGCCCTAAGAATTTCTCATTGGAGCGTGCTTGCTTCGTGTAGATTTCCGAGAGCTTTCCATTTATTTTAACTTCTTTCGTGCTTTTTCAGTTTTCCAGCGACTTTCTGGCTCGACCCCTCGGTATATTTTGTGCAAACACCGTCACGCGCAAATGCATGCCCTTTTTCAACGCGCTGCGTGAAAATTCACGCGATTTCAAATATTTTTTCCCGTAGTTTCCAAAATTTTCGAGAGCGGGGGGGTCGAGCCAGAACACCTTGGTTTTCCAGCGAGCTTCCTTCATTTACGTCGATTTTTTTTTTAATCTTCGTTAAATCTAAAAAAAAACGACTTAAATCATTTTAAAGTTTCCAACGGTTTTCTGCATAAAAAATCAATTTCCAGAACCGTCCGGCCACTACGACGACAAACATCTCCACACGGCAGTTCTCGCTTACGGTCGCCTTCGTGTACCTCAATCGGCCTTCGAAAGTCTCTCACCAATCGACAAATTGCTCATTCATCACATAAAACACGACAAACAACCGGTGCTGAAGCGTGATTAGTGACGACCGACGAGTTGTCGGATGCGAATGATTGTAGTCTACTGGAAATCTCCGAATCAATCCAAACCACGATCATCATGACGAACCGGCACCAAGCTCTCCGCTGAAACGTCTTCGCGCCGAAAGTGGATCCCTATCAACTGCACAAGGCGCATCGCCCGAGTGTCTCACCGACAAAGCAAAGACAATAGAGTTCCACGAGACTGAGATAATGTTTTTGAAACTGGACCACCAGAAGACCAACAACTACAGCTTATCCGAAGGAAACGAAAACGCGGATAAGATATGTGTTGAGCAGCCGAAAACCAGGTAGATCAACCGAGTACGACGACATTAATAATAGACGTCTTCCGTCGAATTCTCATTCGGCAGCACCGAATTCCGAGAAGAAGCATTTCGTTTTTCCGGCACGGGGGCTTTTTTTTGATTACCTAAAAAATTCCCAACTTTTTAAAGTTCAAAAAAGTCAAAATTTTTGTCCATCTGGGCATGACTGCTTATGCCCCGCCCCCCTTTTTCGAAGTTTCTGCTTTTAGGAAAATGTATTCCCAAAGTGCCAGTTTGGATGCCCCACGAATCAAAGGGAGCAGAACGAAGGAGGCACCACGTATTCAAGATCTGGTGCGATTCCGGATCCGGCACCGTACAACTTGAAAACGTGGTGCCTTTCTGAGGGAAAATTTGCCTGCCAAGGTTGAAATATCGAATGCATTACCCGTAAATCGACACGAACTACAGTAACCTGTTATCCGCGTGGCGAGACCCATGCGCGTCATTTGTCGAATATTATACTAAAACCTTTAACTTGCAGAAAAACTTAATTTTTTTTGTTAAAAATTGAGCCAAAAGACTCAAAAATTTCATAAAGCGAAACTTTAAAAAAATATAATTTGTTAAAATTTCAAGAAATATTTATGAATTAATTAATTTTTCCAGGAATACCCCATGTGCCGTCTCTCCAGTTCCATCGGTTTCTCACTTGGTCGGTGATCTGACTTTTGCCTACACGATCCTACAGCCGACGCCATGAGAAGATGCTGCTCGACGAGGCGTCTTCAATCATCGAAAGTACAACTCTAGCAGTGTCTACTGCTCTGTTCTGCTCCAGGAGCTACAATGCTCCAAATATAGGGTCACATATACAATCATATAATCTTATTGCATTTTCGCAATTTCTCTCCACACACATACACACATCATCCCAAGTATTCGTGTGCTGAATCTCAGTTTGAATGCAATGTTTCGATACCGTTTTTATCCCACTATTGCCTTATCGTTTCCTGTTTTATTATATTTCATATATATTGCCACCACCACCACCAACACCACCCTCTCTATCTTTTTTTGTTCTTTTGCTGCAACATCATCACCTAGTTTTCTGTGAATTGAATTTTTTGTTCCCCCGAGTCCCCTCTGATAGGATACATGGTAGGAAAGACAATGAAAATACGAGTTTTTTCAAGGAAAAAAAAATACAAACTAGGAAACTATAGAAACAAAATACTGAAAAAACATTTGAGGCGCAGTAAACCTCTGCAAAGTTCGCAAATCCAAAAGAAAATATTTATTTTTCTAAATTATTTTTCCGCCACTCCAGCCTCATTCTCATTGGCGGGCGCAAAGTCATGTCGATTTACGAGATTAAGATTTTCAACGAGTTTATTGTTATCGATTTGCGTGTAAAGTTAACTAACTTTTTTGAAAATTTTCGCAAAAAATTTTATAAAATGTTCAATTGGCACGAGCAGATCTTCAGCAAAAAAACCGACAGAAATGTGTTAAACTGAATCTCGTAAATCCACATGGCATAATCCAATGAGAATGTTTTTAGCGAAGAAGTTTGAACAAAGGAATATCAAATCAGGGCCAAATTTGGAGCAATTTCTAAAATATTTTCTCAATTCTTTCGGTATTCCACATTCAAACAATTATTCGGCCGTTCCCAAGGTGATCAATCTTTCGATGGGATCCCTTGGTACTGCAGCAGTCAACAGCTCAATCCCCAGCTTCACTATTCGCCACGTCATCCTCGATACGGTATCTAATGGAAACTCTTTGACAGGCCAATCCATCCGAACCTACACTCCCGGCTCAATGGTAAATGGCACATTCGGTGGTAGAATGTCTCGTGATACTGTTGGACGATCGTGAACATCAATTCCCAGATAATGACTGACGTGGTGGGGACACAGCTTGTCCGCCTGATTTGATGAATCATCTCCTGGTGATGATCGAATCAGGTCGAGTTCGGTGAAACTTGCCGCGACAAGTTCGTTCATTCGGCGTAACAGTGCGCTTAGGCGGACTTTTTCCCTTGAGTGGACGTAGGTGAGCAGTTCTTCGTGAACGTACAGAAGCGCTTCGTAGAGGGATTGTTGGGCCTCTGACCAGCTGCAAAAACGAATTTTTTTTTGGGAAGGGTTTTTGAAACAATTTTTCAAATTTCGGTCGAAATTAAACTTTAACCGTAAAACGATTATCCACGGATTTCTGGCTTCCCTCATAAATTGGATTGGAAGAGTTTACCGAACTAGACCATTTTGGCTCGGCTATATCTGGCGCCGAGTCGCGATTTTAGTTGTAAAACTAAATGCATTTGTACATGTGGAGTACACGACTTTGCCACGCGTTGTCCGGCGGGCGATTGTCAATGGATCCTGCATGCAAAAAAAAAAGTTCACTGAGGAAGAGAACTCCGTGATTAGCACCCCCTATTTCTCTTACGAATCTATCTTCGAAATCTTCTATTTTTTAACAAGTCCTGAATTCTGAAATTCATTATAGTAATTTTTTGGGAATCCTTCCATTCCTACGGAACAACATCTCGGATTGGTGACTCAAATTATCTGAATTTTCAAAATCTCCAGAAAAAAATATCATTTTGCCTGAATTTTCTACTTTTAACGGAATAAAGTGCAAAAAAGACTCTTTTTGAGGCACCACCGAAAGGAGAAAGGAGAACACAAACCACGCCCATTTTTTCCTCGTGCCGCCATCGCGCAAGTTTTTCTGCGCGCAAATTTTTATTTTCAACCGAGACAGCAAAACTCCGAAATAACGCATATGTTCTTTATCATCAACGATACTGTTATTTCGGAGCTTCGTTGTCTCGTTTGAAAATAAAAATTAGATGCAGAAAAATTTGCGCGCGGCACGGAAAAAATGGGCGTGGTTTCTGGCGATTCTCCTTTTTCGTGTCTGTTCTCCTTTCTGGTGCCTCTTCTTTTTATATGTTGCGTAATTTTTTAGCCATCTTGGAATAGCCCCGCCCATTACTCCCACAAATCCATATCTACGAAATCTCGAACATTTCCAGAATGATTTGTAGTCTCTCAAACGGGAATATTTAAAATTTCTAGAAAAACCCCATTTTTCTTGAATTTTGGACGAACTTCTGTAATTTCTCAAATTCTGAGAAAAATTTTCATTTGAGTCACCACAAATACTGGAATGCAATCGTAGAAATAGACTTGTGGGCGAAATCAAATAATGGGAAAACATTCATTATTTTTTAATTTTTTGGGGTCACTTATAGCACCTACAATTAACCCCAGAAATCGGAAAGCCAACGTGTCACATCTGACTCATACCCATTCAAACCACACCCAGCATCCACGAGAACACATTCCCGGGGATTCGGTTAGGTCGGATTATTTGCGTCCAAATAGTGAATATTGGCAGGAACACCACGGGCAATCACTGGTGGATATGCTTGCATTTCTGATCCACGACGACGTCCTTCAAACTCCAAGAGCCCGCAAATCGCGTTCTCGTTGTGTACATCACGGGATCCTGATATCATCGAGCTCATTGTCTGAGCTCTGCCACGTTGCACGCGTCACGCATTGAGCTCATTTCGGATGGAGATTTTATTACTCGGCTACGTTCGATCTGCTAGGAAAACTTGAAAATTGGCAAAAAAATACTTTTTTTTTTGAAATTTTAGAACGATTTTTCGGGTGTTCAGAAATATTTTTTTTAGGAAAAAATTGGAACTTTCCAAAAGTTTCAAAAAAATAATTTACAACTTTTTCCTAAAAAAAAAATGAATATTGACAGCTTCGAAAACAGTAAAAATTGTTGGAAAATTTTATTACCGTTAAAAAATTTTTTTTTTTCGTAAAAAAAACTTTCAGTTTAAAATTTGGAGCGTTTACAATTTTATTGATAATTGGTGAAACAAAATAAAAGGTAATTAAAAAGTATTTTTTTTTAAAAATTTGAAAAATTAGATTAAATGTTTATTCTGGGATGAAAAAACCTCCTAAAACCATTTTCTGGAAAATTTAGCGAACTTCCTATTTTGTTAATTCTTTTTTTTCAAGAAAAAATTTTCCACTAGAAAATGGAAAAAAATTGACGTCGTTTAGAGTCAAAATTGGAAATTTGAATTTTTACTAGCCCTTGAAATCGCGCTCGAAAATCGGATTTTTTTTTCAAAGCTTGAACAATTTTCTGCAAATTCTATCTCTAAACTCACAAAAATGATTTATTTCCCGAACATAATTAGCTTTAGCCTGTACTAACTTCTAGAGTAATCAGTCGAATCAAAAAACACTGCAATCGTTCCCTGCGTATCTCAAACTTTTTCCACTGTTAAGTCTTTATCCGGCTAGTCGGATTCCGTGAATTTTGCAGTCTTTTCCCATTCGGATTCAGTTGGTAGGGCGCCTTCCCATAGCTCATCATAGACACTAGTCAGCAAAAAGAATATTCTTTTGAAGATTCGGTATTCCTAATTGCATTATGTAATAACATTCTGGTGTGGTGATTCCGTTATGTGCAAAAAAAAAAACTTATTTATCAAATTTTTTTTTAAAAATTTAATTTATTTTTTTTATCAAACAATTTTGAATTTTTCCCAAAAAAAATCCGAAAATTGTGAACAAATCTTATTATTTTCGTTGAACAAAAAAACAAATTGACACTTTTTAATTAAATTAATTTTCGTTGAGAAAAAGAGATTTGTCGATTTGTGTTCGTCGCGGCAATGATTTTTTTTAACGAAATTTTCCTGAAAAATTCAATATTTCAATAATTCCTGATTTTCTAGTTTTTTGAAAGAAGAACATGTTAAATTTCTATTAATTGTATAACAAAAAATTTCGGGAAAATCTAGAATTAAAAAAAAATGAGAAAAATTCTAGTAATATATTAATTTTAGGTGTAAATTTCGATAATTTTAGGTTATTTTTCAATTTTTTTATGCCGGGCGAAATTTTGATTTCCAAAACAAAAATATGAATATTTCTGACAATTAATTTTCATTCTAGATTTTTTGCACAATTTTCAATTGTTTTCTGAAGAATTTGGTACTTATTGTGTAGTACATGCCCTCATTTTTAAATTAAATTAAATGTTCATTAATTCCTTATAAATTAAACGTGATATACATTTCCTCCTTTTTAGGCTTAAAAATTGCTATTTTTCTACTTAGTAAAAATTAAAAATGAGGGCATGTAATACACAAGTACCAAGAATTTCAAGCCCGTCAATTCTTGTTTTTGAAATCTTTTTTGGGAAAAATTCCATGACATTTTCGCAGATTGTTTCTTCGTTCAGAAAAAAATTTTCTAAAAATTATTTGTTTGAAACTTGGGTCTAAAAAAATATCTCTAGAGCACTTTTTATCCTTTTTCAACTTTTCTGGAAAAAGCTTTTTTATAACTTAAAATGAGTTTCTGTGGCCGCGTTTTCTCTCAACATTTTCACTTTGCGGACAGGGCCACCAAAACCGAACCTGAAATGGCTTTTCTGTCGGAACGCGTGTGGAACATCCGGTGCAACATATGATTTCCGAGCTCCTTTCATCACAACGACCACTTGCTTTTCTGAAACTTTGAGAGGTCATGGCCCACGATAACTTTTAAATGGTTTTCTATGCATGGTGATTTTATTACGGTACCGGGTCTCGACACGATGAATTTTATAGAATAAATTTTTCTGAAAAATTTCATTTTTTTTTTTAGAAAAATCAAATTTTCAAGATACATGGGCAAACATTTTTCAGGAAAAATTTAATTTCATAGAGAAAAATAGAATTTTTCCTATAAAAAAATCTGAGCGTAAATTCGGATTTTTGAGACTCTTTATTTGGATTTTAAAATCCAAATTTTCAAAAAAAAATTTAAAAACCGGAAAATTCCAAAACTTTTTGAGAGTAAACTAGCCTTATATTTTTCAATTAAAATTAATTTTTTAAAAGAAAATTGGAATTTTTAGAACACCAAAAAATTGGCAATTAGTCCCGAGTTCTTCAACGGAAAAATCTGAAAAATCCGAACTTTTGAAAATCTTTAAATATCCCAATATTCAATTAAAAGCGAAATTTCGGATTTTTGAGAAAATTTCAATTTAAAAAAGTCTTCTATTTGTACTGCACACATTTCTAAGACAAATGCATGGCCTAGATAACTTTTTCAGAATAGGCCACCAGGCCATTTGCGACTGACATCTGCCTCTTACCCCCAGTTTGGACCTCTTTTTTTAAATTCATCAAATTCGTCCTTCTCATCGCATATTCCGCATTTGGAATTCGCGATGGCCACATTGGTAGGCTCCGCCCACTTCTGAGCATTTTTTTCTTGGATCCGATCTGTGTTCAGTGGGAGGGAAATTCGAATTTTTTTAGAAATGATTAAAACTGAAAAAAATAGATTTTTTGGGAAGGAACCTGAATTTACGAGAGACTAGTAAAAAGGAGGTAAAACAAAAAATTCGACTTTATAAATTGAGTCAAAAATTAATAGAAAAAATAAACTTAAAATTATGAACAGAAGAACCTACTAAAAAAGTCTAAAAAATGAATGAAAAATTGCAAAAAACATCTTCAAATCTATACGAGACTCCTCCTCCAACAATGCGGTTCACGCGGGTGATGTACCTGAAAAAAAGTGATTTTTTTTTGAAATTTTAGAAAACAAAATTATGAAATAAAACCAAAAAATTTCCGAATAATCGAGATTTTTCGGAATAGTTTGAGGTTAAAAAAATTTTCCCAATTTTTGATGAAAAGTTTTTTTTCCAACAATTCGGAAAACTAAAAGTACCAAAAAATTTTAGTTTTTTCGATTGTTTCAATATGATAATGGTTTTTTTAAATGTTTAAAATTGTATTTTTTCCAAAAATATTATCAATTTTCATACAATTTTATGGTTTGGAGATTTTTTTCAAATTCAGACCAAATTCGATATTCGAAACGTTTCTCGAAACAAAATTTTTCAACTGAAAAACTACAAAAAATCCTCTTATGGATCTTTGAAGAAAAATCGATATTTTCTCAAATTGTTCAGATTTTTTCTGTTTTTACCCAAAGTGCCCAAATTTGAGTTCGCCACGAATGTTTAAAATTATTTTTCCCGTTTTTTCGATATTTGCGGGTTAAATTTTTTTAAATTTGATTCAATTTTAATAAGTTTGAGTTTTTTTACGATTTTTTGTCCTAATTTTTTCCAATTTTTTTCCATTGGTAGAAGGCAAAAAGTGCGATTTTTTTCCTTTTAAAAATAATTATTCAGTTTTTCGACTGTTTTCTTCTCGCTTCCAGATTTTAAGTTCTCGAATTTTTTTTATATTTGAATTGTATCTTTAACTATTACCTAACGAAAAATTAGTTTTATTTTTAGATTGGAAAAGAACGTTCTTTTTCGTAAATTTTAGTGATTTTTGATTCCAAATTTTTGGATATTTTTCAAAATTTCCCATAGAGAAAGTTTTACCAGGCTTTGGTAGAAGCCAGAAATCGATTAAAGCTTTTTTGGGTTTTTCGACAATTTGTCAAGTTAGGAATTAAACTTTTAAAATTTATTTCAAAAATTTTAAAAAACTAAAAGTATTTCTGAGAATTTTTCTGATATTAATTATTCAGTTTTTCGACTGCTGCTTGCTTCCAGATTTTTTCTCGAAGTTTTTATATTTGATTTTTTTAAAAAATACTCTATAAAATTCATTTTTTTTAGGCATTTTTTCTGGATACTTTCTCTTTTCGAAATTTTCGTAAGTGTCAGTGTTTTTCGATTTTTGATTCTAAATTATTGGATTTCTTAAATTTTTTCGGAAAATTCTACCTGGCTCTGGTAGTAGCCAGAAATTATTGAAGAAGCTTTTTTTTCGATTTTTTAGACAATTTTCCGAAGTTTTAGTTAGGAGTTAGACTTTTTCAAATTTTTTTTCAATTTCAAAAACTTTACAAACAAAAAGTACTTTAATTTTTGCGAAAAACAGCATTTTTTTTCTCGAATATTTGAACTTTTTAAATTTTTAAAGCTTGTTTTATATATATTCGAGTATTTTACTCTTAATCAATGAAAAATCTTTTTTTGATAATTTTTTTCAAAAATGTAAAATTCGAATTTGAAATTATTTTCATTCAGAAAAGGGAAACTATTTGAAAACAATTTTTTGTTGAATTTTTCGTAAATTTGAGTGATGCTTTTTGATTCCAAATTTTTGGATTTTTTTTTGAAAATTTTCCACGTTTTGGTTAGGAGTTAGATTTCTTGGAATTTTTTTGAATTTTTTTCCAAAATTTTAAAAAAGAATTTCTGAGAAGTATTTTTTCCTTAAAAAAGAGGAATTTTTTAGTTTTTCGACTGATTTGTGCGTGCTTCCAGATTTTTTCTCCAAGTTTATAAACTTAAATCTTGAAATTTATATTCTAATATTTCAGATATTACCTAATCGATAAAAAACTTCGTTTTCTTTTCAAATTTTAATTGAAAAAAATCGATTTTTTCGATAATTTTTTAACGGCTTTTTTTATTCGAATTTGTTCAAACACTTTTTCATTCAGGAGAATTTGATTATTTGCAATTTTTAATTTAATTTTTTAATCCTTTAAATTTTCGTAAATTTTGAGTGTTTTTTGATTTTTTCCAAATTTTTTTTTTGCAAATTCTCAAAATTCTTATTTTTGCAGAAAATTCTACCTGGCTTTGGTAGACGCCAAAAATTCGATTTAAGAAGCTTTTTTTTGATTTTTTTTGACAATTTCCCAGGTTTTAGTTAGGAGTCATTTTAAACTTTTTTCTTTTCTTTTGACTTTAAAAAAAAGTTTAAAAACTAAAAGTGTTTCTTAGTTTTTCCTTAAAAAAGAGGATGCACATTTTTTTCGCTAGTTTTCCTGATCGACTGACTTCGTTTTTGAATTTTTAAAAATTCAACAAGTGTATTTTTTAAAAATCTAACCGATAAAAGAGTCGTATTCTCGATTTTTGTTTTCAAATTTTTGGGATTTTTTTCAAACATTTTTCCAGAAAATTTTACCTGTCTCTGCTAGAAGCCGAAATGTGTGATTTTTTTCCAAAAAAATGCTGGCTAGTTATTTAGTGCTTGTTTCTTTCTCGAACGTTTTATTATTTGAACTTTAAAAATTTTTATATAATATTAAAAATTTAAATAATAATATAGAATTTTTTTGAAAATTCCTTTCTGATTATGGAAAAAACATTTTGTTATGTATTTGAGAAACTGAAATTTTCTGAAATCTTTTAAATTTGGAAAATTTCGAATTATTTTTGTTGATTATACTCTAGGTAATCGATAAAATTTTTTTCCAATTTTATGAAAAAAATGATTTTTTCGATAATTTTTGATTTATTTTCGGGAATATTTGAAAACAAACACTTGAAAAATAAATCAAACTTTTTTTTTGAAATTTTCGTATTTGAATTTGAGTCTTTTTCGATTTTTGATTTTTCTAAATTTTTGGATTTTTTCCCTCCAAATTCTTCGTCAATTTTTAGAAAATTCTACCTAGCTCTGGTAGAAGCCAAACATTGATTTAAGAATCTTTTTTTTTTCTTGGATTTTTTTTTGAAAATTTTCCAAGTTTTGGTTAGGAGTTAGTGGATTCCCTCAATTTTTTTCTTGAATTTTTTTCAAAAGTTTTAAAAACTGAAAGAATTTCTAATAGGAGATTTTTTCCTTAAAAAGGAGGAATTTTTTAGTTGTTCGACAGATTTCTGCGTGCTTCCAGATTTTTTCTCCAAGTTTTTATAAAATCCTTAAAATTTATATTTTTAAATAATATTTCAGATATTATACTCATAATCGATATAAATTCGTTTTTTTTTCAAATTTTAATTGCAAAAAAATCGATTTTTTCGATAATTTTTGAATTTTTTTTGGGTTACAAATTCGAATTTGCAATATTTTTCATTCAGAAAAATTTGATTATTTGAAAACAATTCTTAAGGATTTAATTTTTTAATCCTTTAAATTTTAGTAAATTTGAGTGTTTTTTGATATTCCATATTTTTGGATTTTTTTCCAAATTCTCCGAATTGTTATTTTGCAGAAAATTCTACCTGGCTTTGGTAGAGGGCAAGCCAAAAATTCTAAGAAGCAACATCAGACGGTCTTCCAAGTCTTCCCAACGGAATCATCGATTCCAAGTGTTGTTTAATCTGGCGAGCTTCTTCTCCAGAAGCATGATCCCATACAGCACCAGTTTCCTTTTCAATCATTCCAGACACCACACTAATCACGCGGACTCCTTGTTTCGCGCACTCGCTACGGATTTTGTAAGTGGGACACTGCTAGATGCAACTGAGTAGAGGGACCCATATCGATTCATGGAGTGAAGCCGAAACATGACGTTAGGTAAATGATACTGCCGTTTCTGTAAAAAATCGATTTTATTTGGACGGGAAATTTTGCCTGCCTACGTGCCTACCTGCCGGCCTATTAGCCTATTTTTCATATTTATTTTGTTGTTCTACTTTTTTGCCGTTTTTTGGGAATTTCATGAGTTCTCGGGTCGGCACGACTTCATGCCCACGTGCCTATCTACCGGCCTAACATGATATTTTAATTCCATGATTTAGGTAGGCAGGTAGGACGAATACCTGCCTGCCTACCGCTGTTTTTTTGAAATTTTTTTGTGTGAAAAATTAAAATTCAAGGGAATGCTTTTTTTTTCAAAATTCAATGATTTTTAATGCAGACCGCGCCTATCTGCCTACCGCCTATTTTTGGCATTTTTTGTGTGCAAAACAAAATCAAATTGGAATAGATTGCCTTATCTTTTCGTTTTTCTAATCTGTTTTCCATTTCAAGATTTTTCGGATAGGCACGACTTCCCACCTACTGTGCCTACCTACCTACCGCCTATTTTTGGCATCCGGTTTTTGTGAGTAGCAAAAAGAGATCAAATTAGCTTTTTCTCCTGTTTTCTCCGATTTTTTTGGCAATGTAGGCACGACTCCATGCCTAGTACCTACCTACCTACGTCTCCTATTTGTCGGCATGTTCTCGTACAGAACATAATCAGATTTTGAAAACACTAATATTTTTGTTTTCTGAATTTTTTTTCCAAATTTTGTGATTTCTAGGGTAGGCACGGACTTCATGCCTACGTGTCTACCTACCTACCGCCTATTCTCGGCCTTTTTGTGACTGAATAAATTAACATTCTTGAAAATCCTTTTTTTGTTCCCTTTACTTCAATTTTTTCAAGTTGCATGTTCTCTAGGGTAGGCACGATTTCATCCATGTATCTACCTTTTATCCCCCTTTTTTGGTTTAGGTCGGCAGGCTTGAGTCAGTGATGCACGAAAATCTAGAAACATAATTTTGATTCTGTACGGTAAATTAGGCTTTCAAGACAGTTTGAATTTCTCGAATTTCTACCAGCAAAAAATAATATCTGAAATAACTTTCGCAGCGAGCCCCAAGAAACTGACTGATGGCGATAGCGTCGACATAGCGGCTTTCGAAAGACGGGAACGGTGTTGTCAGATTGTTGGCGAAAAGCTGAAATTTCGAGGTGAATTTTCCACGTGGAATTTTCAGCACGCTCGAACCTTATCAAAATCCTCGCCGGATGTCTCAAGAATCTTGCCGAGCACCTCATTCTGTGGTGGAACTGTACTTAAAGTGTCCAGACCGCCGAGCTTCTCAGCCACTTTCGTGATCAGCTTCCGGTCTGTCCTCGGCTTTTGACACGTTGAGAAGGCTGTGACTCACCTCCAACCTGAATTTATTCCCGAATTGATTCATTGTCAAGTTCTGAAAATCTTCCTAAACCTTTATATTGTCCTCTCCTTTCCCCACTATTCGGACAGTCTGCGGCGGCGGCGACCTAGTAGCCGGTGAACGCGAGTCTTCTCACTACGCTGCTTTGCCCAGTGTGGACAGCAGTTGCCCCGGTGCTTACGAGTGCACATGACATTACTCTGAAAGCCCGATGATGTGGAGGCACATTTATAGATACACCTAGACATCAGGTAGATTTATTTGGAAATCCGTAGAAAATAAAGATCGTGATAAATCATTTTATTAGAGGGGAGAGGGAGGGCGAGCAAAGGAGATCGCTGACAACTTTCGAAAACCGGTTATTTACTCCAGTTGGACGGCTTATTCATGCCATATTTTCCAAGTTATTTACACTATTCTGTTGGTATTGAGAATGTTGATTCTGCTTAGCTGGCGGCTTCGAGCTAGACATCTTTGTAACTCGCGCTCGTCATCCTTCCGTAGAGTTGACGACCTCCAGCGCTGCTTCCAACATTCCGGGGCATCATGTTCATGAATGTAGTAGGGAACTAGTAGCAGGTGACTAAGAGCCTGCTCCATGAACAACGGCGACAAGTTGTTGGCTGCTGCATATAGTTCCTGGAACCCTGGTGGTGGTCCAACATTCGACGCCTGCTGTGGCAGCTGATCCGGAGAGCTTTGAGATCCAAACTTATTGAAGTCCAGCGATAAATCCTTGAGTCTCTCTCACCAGATTGCACTTGTTGCGCAGAAGCAGCCTGTGACAGACGAGCAGTTCGAAGCAAGCTTGTAAGATCAACTCCCATTCCGTATTGCATAAGAGGTATATTGCTCATCACGAACTCCTGGCACTGGATTGTACCTGTTCATGTAGTTGTTCATGTATGGTGCATATGGGGGTTCTTGAGTGAACATCATGATGGGGTGCTGTTGTGGATTTCCAGTCGGTTGTGATTGAGCTGGCGGAGTTTATTACTGCTGCTGCACTGGGCTGTTGTGGGGCTTCTTGCTGCTGTGTGGCTGGTGCTGCTGAGCAAATTGCTGTGTTAGAAGTCTGGTCCAGAATTGTTGAACTTGCGGCGCCATCCTGTCCGTTGGTACTGATATGAAGCGGACGAAGTGTCCTAGGACAATCCTCAGTTAGATTGACCATAGGAGAATGGAGATGAAGTCGATTTTAAGTGTAATCGCCGTCAGGAATTGACGTCCTTTCTGGCAGAAAAATAATCGAGAATTAGAAATCGTCTTTGCAACAAATTTAACTCCCTCAACTTGTTTCGGGATTATACGAGAAGAGTTAAATATATAGAATTTCACTGTGAAATCGAGGCAAATAGGCGGAGGATTCAATAGAAGGAAGCTGTGGGCTTGGAGCAGCCTCAACAATACAAATGAGTAGTCATGAATGTTCGTTGGTGCAGTTGTGCGAACAAATTCCCCTACAGGATCAGGAATAATCTGGACTGGTGCTGCACTGGAATTGGAGATAATCCTAGTCCTGGTGCTTCACTCAGATCTATTCCTAGATCCGTCCTCAGTTCAATGGTCCATGCTTGATTAGGTTCTGGGGTGCTTTGTACATTTTGATCGTGATGAGTCGACACATTACGCGTCTGCTCCTCAGCCAAAACTGATGATTCACTGCAAATTAAATTTTAAAAAATCTAAATAAGTAAAAGGACAGAACAACTTACTTTTTGAGGAAACCATCTTCATTCTCCGGCTGGTGCGAGGGTTCTGGCTCGAATGCAAATAAAGGCCGGCGCTCTGGCTCTTCTTTAACTGGTGCAACTGATGGAAGTGGAGGTCTATATGTGAGAGACTCCTTGGCGGAGCTGCTGGTTGAGGATTCTGTGCCTGGTACTTTCGGAGTGCTGCTTTGCGATGGGCAGGTGCTGCTACTGCAGCAAATGAGATCGGTGCCGGCGCAGAAGATGTGGGAACAGTGGCGCTGACGGGAAATTCCTCTACTGGTGGTTGTACTTCTGTGACTGTCTCCACTTTAGTCTGCTCCTGGAAAAAAAACACGTTTCGTCATTTCCTTCTTCAAAAAATTCTTACCTCATCAAGATTAGCCGTCTGAGCGCATCTGGGTCAAGTGCTGATGATGGAGCAACAGTTCGGGAATATCCACCTCTGGCGCCACCTCCACGTGCTCGTTCCCACCAATACGGTTTTACAAATCCTCCTCGAGTCGTCCAGCGTGGTGCTCTGCTCCTTCCTTCATTATATCACGGTTATCCTGATTATTATCTCGACTTTCTGGAGCTCCATTGGATCGCCCGCGGCCTCCTCGATCGTCGAAACCGGTGACTCCACCTGAAAAAGACATATGAATATTTGATCTATTTAAGCACGAACCTCTGCCTCTTGCTACAAATCCTCTGTTGTTATGACTGCCCTCTTCCGGCTTCTTCTTTTCCTTTTTAGCTCTTTCTGTTCTGTGCACGAGTCAAGTTTATCTCCAGCATCCAGAATGTGATCGAAAGTGTTGCGCCGTAAAGATTGTTGTCAGTATCCAATAGCTATCTCAGCTTTTGCTTGTGTACATCCGGTGGTTTTGATAATCTGAAAATGAAAAAGGACATGAGCAGTCTGAAAAAACCTCTCTTGGGAATGCGCGAACACTTTAATTAGCCCAAATGAGTAGGGCATGTGGGTACTCTTACTCTCGCTGCACCATCTCAAGCGCGCCTGCTTTTGTCCTGTTCAATTTGCCATCTGGCCCCGTCTTATCGATTCGAAATTCCTATTGACACTGCAAAGCGGACACTAGAGAAGTTCAGCCTAAACAACAAAGTCACGTGCGTCATCATGTCGGTGTGTGTCGAGCGTTAGCGTGAGTGCAAAGATTCACTATTGAAAAGCGTCATTTCCAGCTTGGAGACTTACCATCTTGATCATAAACTGTATGTCCTCCTCATTTCCGGAATTTCCTTCTTCAGTGTCGTAGGGGGCAAGTCTGATCGCTGGTAGCTTTTTTGTCGCCTTTAATACCCATTCTGAAAACAAATTATAAATAAAAAGGGTCAGTCATGTGAACGCAGACTGAGAACTAGTTGAATGAGAATCACGTCTTAGAATACAACTATCAAAGGAACGTTGAATGAAAGGAAGCAAATAGATGACACACCACTAGTAGGACGAAGAAATATGGAACCTTCCATCACAAAAACATTATCAAAAGAAAAGCCTCGTACAGAAGACTCTAACACAACATGAATATATCAGTTCAGCAATACATCACGTTACGCTTTGGAGGATATTCTAGAGCAGAAAACCCCGACTACAAAAATTTCGAAATGGAAAATTCGAATGAACTGCTATACAATGGAGAATCCTATTGAGCGATGATAAAGTGTAGGTGTTACTAGATTGAATCAAAATTTCGAAATGTAACAATACATTGAGTGAAAATTTGGGTATTTGCAGAGTGTGTATCACAGCGGTAAAATCAATGTTTCCACTAAACTCAAAAGTTCTTACGCTGAAAGATCAACATTAAAAAAGTGAATCACCGCAACCTAGACGAATCGCGTTGCCGTCAAATCTCGCAAATTCCCGGAGTTGAAAATGCAGTCGACCGCGACGCGAGCGGCAACGCACCCCGACCTCCAAGCGGCATGGGTCTCGCCACGACCAAAAGTACGACGACAGCCTCTATCTGGCAGTATAAAAGGCGACCATTTTCCGCTATTTTCCGGTAAATTTTGCGATCGAATGAAACTGTGTTGCTGAGGGGGTGCTAATTTTCCGGAAGTTTACCTATTTAATGTAAAAATGTGAATTAAACAAAAGAAAGTGGGTAGGATTATCAAGGAAACACACTGTTCTGGGAATTCGATTTTGTGTATGGACTCTTATGGCGTCAACATTATCGACACGAACACTCAACACCTTGTCACATTTCTGAGAGGGAAATATCATTTTCAACATGAGTCTTCCCAGTTCATTTCGACTCGTCGGTTCAGGTAAAGGCGATCGGCGAGCGATCAACCAGGAGCACACCAGAGCCGGTAATTGTTCTTTTTTATTTCAAATTTCTACAACAACAAAAAGAATTAACAATAAATTCCTTTGAGGCCCCTACCCACATAAAGTAGGAAGTCGACTACCAAGATGGTCATCAAATGGCTCCGGAACCCGTGGAAGCACCAATGTATAAAAATTTAAAAAAGTTAGAAAAAAAATCTGAATCCCAATTTCCAGAGGCTCAAAACGATGAAATGTAGCCACCTCAACCTAACCGCAGATGCAGAGAAGCATTTTAGCATAGCCAATGGCTCCCCACAAAGGCCGCCCTGGACTCCACTAAACTCTGCAGCGGCGGCCGCCGCTGCTTGAGATGACAAAAACGTGAAGGGAATGCGTCCGCTTTCTGAAAACTTTAATTAATGTGTCGAATAACGATGATCCAGAAATGTCGGACAAGGCCGCACGTCTCAAAGAGCTTATTCGAGTGAGGAATTGAGCGAAAAACGCGATAAAAACCGGACAAATTCGGATATTTCAGGGTGATTTAACTGGAAACGACGGCTGAAGAGTTTACACGAAATCTGCAACAGATCAAATCCCAGGCTCAACCGCATCTTTTACCTTGAGAATACTCTTCCGGCAAGGAATGCTGTTCGAAATGGTTCGGTTTTATGTGCAAAAAAATTAAGATCGCGCATATTCAAAAAAAAAATTATCGAAAAACAGGTCGAGTAGCATTGCGAAAAACTTGAATTAAAGGTAACATAAAAAATTGCAGAAAATCCGTTGAATTACATTTTTCCAGATTGTCTGTAGAAATTCCATGATAAAAATTCAAAATTTCCAAATTTATTGGCTATTTCTAGGCTCAATTTCATTAAAATTCCATTTTTGATAGCGAAAATTATCAAGTTTCTAACAATTTCAAGCTATGTTTTTGGTGATTTTTTCAATTTTTCGGCTTTGAAAGTCCATTTTCCGGATTGTCAGAATATATCCGAGTTCCACAAAATTGAGTAAAAAAAATTAAAAATTTCCCTTTATTTAAAAATATTTTCAGCTGTCAGTAATAAATATGGATTTTCCGCAATTTTCTCACAATTTTGAGCAAATTCCTCAACCGATTTTCAGCCAATTTATAAGGATTTGCACCCAGGGGGTTGTCATAATTTAGGGTTCAGCTGAGAAATTAAGTAGTAAGTTTCTGAGAAAATTTTTATAGATTTTCTCAAATAATTTCAGCTCAAAAATTCGATTTTCAGAGCGCATTTCCAGGTTTATTAAGATTTTGCCACCAATTCTTTTAGCTTAAACTTTAAATTTTCCACATTTTTTGTCTATTTCCAGTATATTTCTTTAAAATTCTATTGTTGAAAGCAATAATTATCAAGTTTATCGCACTTTATCAATTTTTCCGCAGTATCTTTTTGTGATTTATCCAAGTTCCACCAAAATTGAGCAAACAATTATTTAATAACTTCCCTTTATCCTCTTAATTTCCACAAATTTTCTCGCAATTTACACGCAACTTTCATAATTCAGGGCTATTTTCAGCTGAAAAATTGCAATTTAAAGTTTTTAAAATGTTTATAGATTTTCTCAACATTCAGCGTCAAAAATTCTATTTTTAGAGGCGCATTTCAAGGCAATTTATGAGGATTTTTAACTATTTTCTAGATGAAGAATCTTTTTTTTTCCTCTTGGACTATTTTCCCTTATTTTCAGATTTCCAGCACTGCATCAGTTGAAGGCGTAAATCCACCGCCTGGCTACGTTTGTCAACAATGCAAGAACCCCAGGACCCCCTCAGCCACCGACGTCCACCTCAACAACAATCCCAGCAGCAGCCACCACTAGAAATGCGTTAATCCGAATCAAATACCCCCACAAATGGTTCAAGGGGGTCCCCATAGGGTTGTAGGCGCCCGGCCAATGATCAGGCCTTCGAATGGGCCGCGGCGGCCCTAGCCCGGCCTACAATGCGGCCCCGTACGAGGGCCGATGGGACATCAGATGGTCCAGATGCATCCTCCTCCCCCACCACAGCAGATTCAACAGCAGCACCCGGCTCCCCCTGTAGAAATGGAGGTGGAAGAGAATTTACAGCCTACCGCGGCGAGGGACCGACGGCCAGCAATATAAGGATCGCTCAAACCGTCGCTTCTGAAGCGGGATGAGGTGCGGAATAGGATCACGAAACGAATGATGTCATCGTGTTCGTGGAAGAGGAGGGTGCGCTTGTCGCGATTTCAGCTGTTGAGTCGCATTAACTTTAAGGAACTTATTACACTGATGGCGTTGCAGAACATCGGGTGGAAGAGTTTGAGGTATTGAGGAGAATTGATTTTGCTTCAAAATACGGCAGCGAAAACAGCAAAAATTAAGGAAAAGGAAATTAAGACGGCTTAACAACAATTTTACATTAAAAAAAAATTTAAATTTCAAAGGTTCCGAACTATTTATTAAAAAAACATCTAGATTTTAAAATCCAAACAAAGTGAAATTTACGCTGAAACGCGTTAATTGTTTTTCAAAGTCCCAAAATATAAAAATCTGAGAAATATTTTCAAAAATATCTCCAATTTTCCCCAGATTCCGAATATATTCAAATTCAAAAAAAAAATTTCACCTTTATATTTCAGCTTGAAGCTATTCGCTTTGTGCATGCACACCATGACCGACAAATTTTTTCAAATGCGCGCCCAGATAAATAGCTTCTCATCGGGGGGCTTACTCGCTTCGTGTCGATTACGAGTTCATTTTTTAATTTCTTTTAAGCTTTTTTTTTCAGTTTTTCAACGAGTTTCATTGAAGATTCTTCGTCGATTTTTTGTCATTTTTTGAAATTTTGTTTTGTGTCAATTTGACACTTTTTTAGGTCAAAACCCCTGTGTTCGTCGATGACGTAAAAATATAAAATTCCGGGACTTTGTTTGGAGATATAAAAAAAATATTTTAAAAATTACGCACAAAAAAAACTGACAAAAAAGCATAGACAAAATAAAAGAAACGAAAAAAAAAAAGAAACTGTAAAAAAGCACGAATAAATTTTTTTAAATAAAGGAGAGCTGCCGTAACCATCGACACGAAGCAAGCATAAAATGGCTTTTTTCCTAACGATTTGTGAAAAATCCGAATTTTCCATCCTAATAAAAAAGCAGAATTCCGGAGAACTACGTGGCAATTGATGACGTCAAACGGCGCGTGATTAACTTCGCTTCCTTGAAGATTTGGATCGTCAAGAGGAAGAATTAAGGGAAAGTCGAGAAAAAGAGTCGCTAATTCGAATGAACAAGAATAAGAATAGTGGCAAAGAGACGATAGAAAAAGCGAAAGAAATGCAACACAGGAGATGCAGAAGCGAAAAGGAATATTCGAATGCGGCTGCAATTAGCACTTTCCAGTAATCTAAAACTGTCAAGAATAAGTCCGTTTTGAGCGTGAAATGTTCAAAATTAATTATAAAAAATAGATTTAAAAAAAACAATTTCCTCACCAAGGGCCGTGTCATTTTTCGATTTTTCGGTCTACAAAAATTCGAAAAATGAGTAAAGTTTCGTGTTTCGATTAAAAGTCAGAACTGAAACACCGACACCTTTGTTTCTGAGATTTGGATTATTGGAAATGAGCAAAAAAAAATTATTCAGAAAAAATTGTTTTACAATGCTGAAAAATCGATGAAAAAATAAAATAAATCAATAACTAATTTAAAAAATGGAGAAAAATTTCGATTTTTTCGTTTGTATTTCACAAAAAAAAATTTTTAGAGATAAATAAAAATTTGCAATTAAAAAGAATTACTATTTAAAATAAAAATTGAAAAAAATAGAAAATTCAGAAAAATAGCGAAAAATAAGTTTTTTTCCAGAAATTTCGTTAAAACGATCAAGATCTTAACCCTAAAATTTAGATAAAATCAATTTCTTGTGGTTCTTAATTTGAAAAAAAAAACAGTACTTTCCATTAATAAATCACTTTCAAGCGAATAAATTCGTTTTTATTGCGAAATTCGCAAATTACGAAAAAGTGAAAATAGAAGCTGAAAGGAAAGAATGTTTAATAAAGAATATTTTCGGCATTAATTGGTTTTTATACATATTTTTTTGTAGAAGTAAAATAATTACTAAAATCAGTGAAAATATTGAAAAAAATTTTAAAATCTGGAAAAAAAGCAACAAAAACTTAATTTTTCCAGAAATTTCGTTGAACTATTCGGTATTTTAAGCCTAAAATCAAGATACAATCAATTTGAACAAAATTTGCATGCTTTTACTAAAATTAATTCGGAAGAAATAGGAAAAAAAAGAAATTCTCGGAGAAATTTGAATTATTGGAGAAAAGCTGAACACTTACAAAAAATTTTTTACTCCGTTTTGAGAAAAATTTTTGAATAGAAAAAATTTTAAATTTTTAGAATTTTTTAACTATAATTTTTGAATTTCAGTGACTTATAATCACTTCCAGAAAGACAATGAACGAAAAACAAATGCTTATCGGCAAAAAAACGTATTCTTAAAAAAAAATTTAAATTTCTAGTGACCTTGAAAAAAAAACCACATTTTCCAATAATTTCCAGGAATAAACTAAATTTCTTTGGAGAAATTGGAAATTTATTTCACATTTCGAAAAAATTTATATAGAAATAAAAATTTATATGAAAATAAAAAATTTGCAGCTCCTTACAGCAATGAAACCTGTCATTTGTTGAAAATTAGTTTTTTTTTAATTTAGAAATTCTCTTTTCGAAAAAAAAGGTTTTTTTAAAACGTGATTAAAAATTAATTCATTCATGTCATTTTTCGCCAAAATAAGGGAAAAAATAATTTCTAAAATTAGACAAATACCTTTTCTGTTGAAAAAAACAACATTTTAATTTTCTTGTTTTTTAAATTGCTTCCACTAAATTCACTTTTTGAAGAAATGTTTTGAAATTTTTACTGAAAATTGTTGGAAAATTATTAAATGTGCATTTTTTTGCAATTTCCAGTTGATAAACTAATTTCGGTTCAATTATAAAATAAATTTTGAAGTGGAACCAATTTCAAAAAGATACATTTTTTACAATGTTTGTTTTTGTTGATAAAACGAGCTTGTTTCTACATACCGCTTTTTTACATTGAAAATAAATTCAGTCAGATGGGAACACACGGGAGCCGCAACGACGCACCTCGTCCACGAACAGTACGTGTAACAACCAATCGTGAACTACATCTTTTATTCACGGCATCCGGATAGCCGATTCACAGGGTAGCGATTTTTTTTGTTTAAAAAATTTAAAAACACCGTATTAAACATTTCATTGGAAAATACTGATTCAAAAAGTTTTCAAAAAACTTTCAAACGAATGGTAGTTTATTTTAATTTTAAAAAATTCCAATAAAAATCAATTTTTATACGATTTAAAATTTTGAAAAGTTATCCCATTCGCTTCTCCTAATAAAACTCATTTTTTTTCCAGAACATTCATCCGTGAAAAGATGTCATACGGTGGTCCGGTGACAGTCGGTACAACTATCTGAACTAAAGAAATCTCATGGAAAAAGGAGCGAAAATTCTGCTTTCGCTTTTTCGTTTTTTAAATTTAATTTTATTTTTCCACAAATTAATCACTTATTTCCAGTCAAATAATAATTAATTTTTCATTTTTAAACGAAATGCTAGACATAGAAAAAAGCTTCTTTCAGCAGAGATTTGCAGCCAAAAATTTCAGATTTTTCACGAAGAACAAATTCAACAGCTAAAAATTGGCAAAGTGCAAAAAAACCAGAATTAGATATTAAAAATACAGGAAAAATCGAGAGAGTTACAATTCAGAAAAGTAGGCAATTTTTTTCAAAATGTCTCAAAAAGAATATTTCGGTATTTTTTATTGTCCCTCTTCTTGAGCACTGAACCTCGGCTCGTGTTGCACCAATCGAACATTTTGAGCGTCGGTGGAAGTGGAAGCTCATCGATTATTCGCGATAGACACCGTCGGCACCGGCGCCAGATTTCTACGGGCGAAGGTGGATGTCACGCGCTGGAAAAATTTCTAATTTCGAGCTGAAAACTCTTTATGAAAGCAATATTTCATAGTTTCAATTCAAAGTTCGAATTCCTCGTAAAATTAGTCGGAAAACCGAAAACTAGAAGTAGGCTCTTGCTCTTTGAAATCAAGGCGTACGGTATCCTCGAAAGTACGCAAACACCGAATTTTGTTTGTTCTTTTGAAGTTTTGGCGCCAAGAACACAGTACGAGCCGGGGTCTCGACACGACAAATTTTTAAAATTTTGAGGACCCTGTAATTTCAAACAAAAAAAGGTTTTTTTCGAATAAACTTCGAATGATACGATAAAAAACATATTTTAATAAAAACCTTGGCAACGAAAGTTGAAAGTACAGTACACTCTTCAACGGCGCACACCTTTTACGCATTTAACTTCCGTGGCGAGACCGGATGTAATTTTTGACTAAAAATTAATCGATAAATCCGTTAAAATATTATTAAAAATTTTTAGATATTTTTCAAAAAGACTGTCGAAAAATTGTTTTTGCGGTTCGATAATTTTTCAGAATATAAACAAACAGTTTAAAAATTCCAACAAATTTTGTTTTTCATACCGAAAAGAAGAAAAATGGACAAAATAGTAAGCTATTTTTGTGTGTCAAAGTGTCTTATTTCGTCTTGATCTGACGTAGACCGATCTACAAAAAATGCGGGAGAAGAGACTCAGTTTGGATTTCTCAACAGAGTTTCGCATGGTTAAACGAACGTGCTGACGTCACATTATTTTCAGGCTAAAAAATTCCGCCTTTTTTAGTAGACCAAACCGTAATGGGACAGCTTGGCACCACGTGACACCGCCCGCTTCTCACCTGTTCGTGATTTGGGAGGGCGAGCTGCCAGTTCTTTCGAAATAATCGTCTAGCGGGGGACTCGATGCCGAAGGAGTAAAAATGTTTGATTCCAGTTAGAGGAGCATTCTGACACATGCGTATTGCACAACATAATTGACGCGCAAAATATCTCGCAGCGAAAACTACAGTGATTCTTTTTAAGTGACTACTGTATCGCTTGTGTCTTTACGTTAGGCATCGATAGAATATTTTTAAAAAAGAAGAAAAAAGAGGGAATGATACGAAGAAAAAAAGGAAAAAAATAAATGCATTTATCAGAAATCGAGTTCGTAAATCGAGACAATCGGTACTGTAGTCATTGATTAAAGACATCCTGTATGTTTTCGCTCCGAGATATTTTGCGCGTCAAATATGTTGTGCAATACGCTTTTTAAGAATTTCCAGTTTTTTCAAACCTTTAAATACATTTTCGCGGTTGTGCTCTCGGATTTCGGGGAACGTATACGTGTATCCGCGACGTTGACGGGGTTGAAGCAGGGTCCGTCGAACACCCTAGCTCTTCGTCTTCCGATACTTATTCTGTTGATGTTGACGGTGATTCCTGCTAGGTTCCTCTAGAGCATCTGAAAGCTCTTGCTCATCTTCTGATAAATCTCGATTGGGGCGTTCAACCAGGCCGGTGGTGGAAGGATCCTTGATGAATCATTACAATCTCCATTCTCGGAGTATTTGGAGTTTCTGGTCGAGCTATATCGAGGCCCCAAAGTATGCTTCTGATGATGGCGGGGTCTATCATGATTAATCGTCCATTCGAGCACATATGCTGGTGCTGGAAGGATTGAAAATTGTAAAAACTAAGTTATCGATCTTTGGCCAAAAAAATAATATTTTCTCAAAAATTTTGAAATTCTCGACAAATTTATTTTCACTACTGCCGGTACAGAGAAAAATTGTAGATAGTTGAAGAGACACAGATATCCCGGGAACCAAGGGACGGGGCGGGGGATGTCTGTGTCTCTTCAACAACCTGCACTCTGTGCAATAATATACTTTTTCCAAAAAAAATACATTTCAGAAGTAAAAATGGACAATTTCGGAGTATACACAATTGGAAATTTTAATTTTTAAAAAATTAAAAATTGTTTTAATTCGGAGTTTTAGACGGAAACAATTATTAAACTCTAAAATTTTTAAATCGAAAAAAAACAAGTCTGAGACTGAAAAAAATTTCGAATAAATTTTGTACTGAACAGTATATATTTCGATTTTTTTTTGAAAATCACATTAAATGTTTTCTCGCAAAATTCGGATTTTTTTTACCTGCTCGATTTTCAGTAGCCAGAGCTGTATTTCCGAGATTGGCACCATCCAAATGTGCTCGGGGCGCTGCAATTTTGACATAAAATTTCACTAAAACGCCAATTACCTCGGTACTTATACAAATTTGCTACTAGAAAGAAATACTACTGTTAAGATAATCGAAAGTTTGGATTGACAGAAATCCAATGTTTCAGCTTCTAGAACCAATATTTTTATTTAGAAAAAAACTTCCAGAAAAATGACTTAATATTTTTTTTTAGAACTTTTGAACATTTTTCCTGATTTTTCTTTTTTTTCCATGTTTGGAACTTGCTGGGAATTTCTCTTTTACATTCCTTCATCCCACAGCTTCGCTTCCTAGGCCTAAGCCTGAGCTGAGCCTATGCATAAATCTAAGCCTAAGAGCCTAACCCTATGTCTAAAACAAAAGCGTGGACAGGCCCAAGTCTAACTAAGTCTTCAAGCCCACGCTCAAATTTAGATCGACTCAAGTAACTACTTTAAAGTTGGCAGAGATATTTAAATTCAAAAAAATTTTTAACGCAAAAAAAAAATACATTTAAAAGAAATTGTTTTTTTTAAATAAAATCTTCACCTTTGCGTAAAACCTTGGATTTCGGTCTCCAATTGAACATTTCTTGAAGGACGTCAGTTCTTGTTTCATTCCATCGACGGACATGATCTGCTATAGTATTTCGAATATTTTGTATTGTTTGCCCTTCTTGTACTCTGGGATGACTATTATTACGACCCAAATATTGATCCATACGTCATCCAAGTGATTACGGGTTCTTCTACTGGGAATGTATATAATCACTTAATTTAAAACATATTTTTTAGTTTATTTACCTTTGATTCGAATTAAAAAAAAAAAAATAAACGGTTAAATCCTGACGGGAGCCAAGAATTGGGCGTGTTTTAGGACGTACTCTTCACTTACGCTTTGGTCTACAAATGCGGAAGACGTTTGCCCCAATCACGTCAGCACGTTTTTAATCATGCAAAATCATTTGACTGAGTTCTGCGTCTCTCCTCCCGCATTCTTTCTACGTAGATCAAGCCTAAAGGAATGACAGCTGGAAAATAAAAATCGAACCCATTTTCAAAAAAATTACTCAATTGATTGTCTGCTGGAGTTAGTTGGTCGATTCTGAAAAATATTAAAGTGTTACTAAAAATTTTCCTTAGCAAAATAGCGCGGTTGCATCAAGAAAGGCGCGATCTGATTTTTATAAGCCCGCCCTTTAATGGAGGATCATCAATTTCTAGGAAAAATCGATATTTTACTAAAAGTGATCCAAGTAAATCAATAAATCGGAAGATTGATGTTCCGTGCTTTTTTGCAAAGATTTATCGAAAATGATTTCCATTAGAGCAAGCTTGCAATCGTTTTTTCACAAATATTCAAATTTCTTACGGTCTTGGATCAAAAAGTTGGCGGGGCACGCCGATAACTCTTGGAATTAGCTTAATGCCTTTGAACATGATCCATATACCGTATTTCTTCATCACCATCATTGATCCGCAAATCTGACGATTGACACGTGGATTGTAGGCGTGTGGGAACCGAATGTCGCGGCGGCCTGACGAGCCAAGTAGGTCAACGTGCGGGGACCAACTAAAAAATCCGGGTTATTGTGATTTCGTGGTGAGACCCGAAAATAGTAGAATTCCCTCGTACATCCTGTGCCTAAGCAGGTATTCAGTTCTTGATGGGTTGATGCGGTACCTGCATACACCTACCGTCTGCCTTTGTCACTGCCTGCGTCCCCGCCTGCGACTAAATGTGTGTATCAAAGGCCTACCTACAGTCTGTTTATCTGCCTCAACGTCTTCATACCTACTTGCCTACCTTGATTACATACGTGCCTACGCGACTACCAATTCGGCATACCGGTTGGCAATTAGAGAAGGCTAACGTAGGTAAGCTGGCAGGCCTGAAATTTGATTTTTGCGAACCGAATTACCTTTCGAAATGCGTGCGTTGAGATTCCTCCTTCGGCAGCCTGATCATTGGAGAAAATGTCATACTTCCAGGGACGTCATACACAGTACGATGCTTGGAAACTCTTCTTTATCGGCACTGAAACCCTTTAAAAGTGGAGGAGCCAACAACTAGACGGAGCCCTATGTAAGGAGTATTGTTTCCGGAAACATTTCAAATTTTAGGCTCCACCCACTCACCACGGAAAATTTCATTTTTGGCCGCCCAGGAACAAAAATAAATGTGCAGAAATAATGTATTTAAAATTGTAAGGAAAAACCATGAAATAGGGTGGAGCCTGCCTGCCTGCCGGGCTCCGCCCACTTCTGGCCAAACCATACCCCCTGTATACGTGGCATGACGAGTCGTCTTCCCACATTCAACATTCCAAGCATTCGTTGCAACAACTGAGAATCATCGGCAACGAATCCGACAAATATTCGATCATATCGATTTTGATGAGATTCAGGTGAAAGTTGTGCTTACATCGGTGATGTCACACACTTTGAGCTCCGGCCGAGCCAAGCGAGCTCGCTTCGGGTGTAGTTATCCATTGATCCATGTTTCCGGGTAGGTGACGAGACTCGTTCTCGTAGAGTTCGATCCCATGGTTCGCTATATACCAGTTTCACCTTAAAATTGTTGTCAGGCCACGCCCATTTTTAAAAAATGAATTAAAATTTTCTGTAGAAGAAAAAATTTCAAACTTTGGTGGGGCATTAAATTTTTTCACACAATTCGGCGGTAAATTCAATTAAAAAATTCTTTTTTTTTTGGCGGGAAATGTGCCGCAAAACAGAAAAACTGAAATTTCTAAAAAAAAAGTTGGTGGCCGAGTTTCCTCATTTTCGTGGTCAGAAAACTCGGCTACCGATTTCTTTTGCGTCGCGCCCTGTGATTACTTAAAAAAATCGGTGGCCGAGGATTTTTATTTTCGCGGCCACAATGAGTAATGAAGATTGCACAAAATTGAAAATAGGGAAAACGCGGCAGTCTAACATGTGCCACGTGGCCCGCCGTTAAAGAAGAGCCCTTGGTGGCCGAGTTTTATTATTTTTCTAGGCCACGTAACCAGAACTACACCCAATAAATGCCAGCAATCGTACTTAAATACCCTGAACCAGTTCCAATATGAAGAAACGAGTGTCCCTTACGCAAATCCAAATAAGCGAAGAATTTCGCTTAAATATCAATTGCTCCAACACGAAGAACTTGCTCACGGATAGAATGGACCGCCACCTCGGTTCGGCTGTGGAGGTCAACGACGGAGGACGTGTAAATTTCTGTTCACTAATCGGAAGAAAATCGGATCGATCGACAAGTCGAAAGGCTCGTTCGATGTTCGACGACGGATTGTGTCGTTTTTTACGAGAAAATCGATAAGATGTCGAGTTTTGGCTTTCACTATTGCCCATTTCTGGAAAATCGATTTTTTAAAATTTTAGATTTATTGATTGATTTTAAATAAATAATTAGATGTGAGCAGTCATGTATTTTTCCTTGTATATTTACGAGAGAGATCTCAAAAAATTATTCAAATAGGAAATTTTACGCCAATAAAATGTACAGTTGTGTGCGCCTTTAAAAAGTACTGTAATTTCAAACTTTCTGGCGCAATGAGTAGTTTTCTTTAAATTAAAAACAAAAAAAAAGCAAATCAAGATACATACAAAAGTTTAAAATTACAGTACTCTTTAAAGGATGCACAACATTTTGCATTTAAAATTTGTCATGTCGAGACCGTAATTTTAACGCAAAAAATGAATTTTCGCGTCTGTGTAAAAGAAGTGAGTTGAGGAGAAAAAACAATTGAAAAATCAACAAAAATTGAACTTTAAAAATCAAAAATCGTTGCGAGTTAATTTTTTAGCCTTGAATAAGCCTTAAACTAAAAAAAAAATAATCGACTCAACATCAATAATTTCGTTACAAGACCCAAATTAAAATTTTTTATTTTGGGATAATCTATTCCTAAAATTAATAAATTCCAGAGAAACGAGTAAATCGTGGCGAGACCTAGCATGTACCTTTAATATCGCCTCAAATTATTTTGGCCCGTACATCTCGAACACACGTGTTGCCTAGCTATCGAACAAAAAACGAAAAAAAAAACAGGTTTCTTTGAAATGAAGATAATCAGCGACACAGTGTGGCAAGATGTCTCAAATTATTGGAAAAAAAAAACGTGAAATTCTCAGAAAACGGACCGTTCTGTGGCAATGGAATTGTGAACGGCGTGCAAGGCCACGACCTGTGAAGAGGGCGTGAGAGTGTAGAAAAAAAGGAGGCGAGAGAAAACGGCTGACCCGTGGATAGACTTATTCAGGAGACGCAGAGCGACCGTGAGAGACCTAAGCAGGAATATTTGAAAAGGCGTGCAATAGTGTTGGAAATTCCCATAATAAATGGGTACGGTAGGTATGACCTTACGGGATATTTGTGGGTCTCGCCGCGACGAGTTTTCAAGGTGCATAAGCAGTTTTTGCGATGGGTCTCGTCACACACGGGATTATAGATTAAAATTGTTGATTCGAGATAAATGGAAATTCGAAGACGTCTAAAACAGTTAGAACTTTATTTTAGTTTACATTGAGCTCAACTGTCCAACCCCTTCAAACTTTTTCCACTTTTTTCTTGATTTACTTTTACAATGCCTTTATGCTTTTCGGCCGTTTTCCTGGGGGTTACGACCACGAAATAGAATCCTAACTTGGTAAAGCCTAAGCAAGACTAAACCTTGGTCTTTCAATTATACATACACATCCTTTTTAAACGATATTAATTAATTTACAAAATACCAAAAAAATATACAAAAAATGATTTGAATATATGCGTTTCCCGCTAAATACCTACCCCCAACTTTTGGTCCCGTGGAGCGCGCTTGCACTTAAACTTCAATTGTTCACATCCCCATCTTGTTTTAAATTGTTTTTCCCTTTATTATTATTATCCTTATCACGAGATGCCCTTGCAAAACACATTGTAAAAACAGTATTCTACCTCAACTGATAGATTAATAAGATTTTGTGTACCCCACAGTCCTTCAGGACCATAAAAATATTGATAATTGCTGATAAGCTCTCTCAGTGGTCTGTAGTTTTGGTGATATTTTGGGCAACAAATTTAGATTATGGAAACACGGAAATTCTGACAATGCGTTTTGCGCAACATATTTGACGCGCAAAATATCTCGTGGCGAAAACTACATACGGTAATTCATGACTACTGAATCGCTTGTCATTGTTTTACGGGCTTGATGTTGGAAATTAATTTATTTTCGAATTGTGACAGCAACCGATATTCAGTTTTCCTTTGATTTTTTGTTCCGTATTATTTTGTTATTTTTATGTGTTCTTTCTTTTAATATTTTATCAATTAATGAATGATTTCCGTAAATCGACACAAGCACTACAGTAGTCATTTAAACAATTACTGTAGTCGCTTCGAGATATTTTGCGCGTCTATGTTGTGTAATTCGTAAAGAAAGTTTGAAATAATAGTTTTTAATTAATTTCTTATTCATTCACTGTCAATTCTCACCGAAAAAAAAAATCCAAGTTCGCCGACTTGCGGCACGATGCCTCTCCAAAAGGTTCTCAGGCCCATTCATGTCATTCAATCCATCCAAATGAACGACTTTTCGTTCAGGGCCGCCCTTCTTCTTTTTCCGGTTTAGTACTTTTTCAAACCGAATAAAAAAATCCGAAATTGACTGCAAGTGTGCTCTATTTGAACTTAGACTTCACGCTATTTCGGAATTTTTTCCGATTTTCTCAAAATCTTTAACACTTTTCTAAATGCATTGTTGCATTAGTGACATTTTCCTAGAAATTCTACTGCAAACGCGCGCATCAGTTGCGAAAGTTTTTGGGTCTCACAACGATTTCGGAAGAAAAACGTTTTATCCGAGACCCGGAACACCATGCCCGGATGGAGCGCGTTTGGAATTTTTTTGGTTAAAAATTTTGCGCAACGACAAAATAACCGCGAATTTTATCGTATTGTTAAATTATGACTTTTCCCGGTCCCAGAACGAATTAAAGCAATTATTATGAAAAATCAAGACCACAAAAAAAAGCGCAATAGAGCGCGTGTGCACCTTTTTTTCTTTGAAAAGTCTCGTTTTTTTCTCGGTAAATTCACTGTGACATAGACCTTTCTCGGAAAACGAAAAGTGTAGTAATGGAAAGTGAACAAAAGTGACAATAATCTGAATTGCGTTGTTGTATTTATCTTCTTTTCTTTTTAATCTGCGAAACATAAGTTTTGGAGAGAAAGTGATTTTCGACGAAATTTTCCTGATTTTGCTAAAATTGTACAAAAATCATCATTTTCTGTGGGGTTTCTCATTTCTTATCCCAAAATTTATGCGCCTTTAAATTTGGGGGATTACTGTAATGTTTGTATTTTTCAACTGTGTTTCGGGAACACAAAATTCTGAGAATGAGTACTGCACAATATATTTGACGCAATATCTCGTAGCGAAAACTACAATGGATTAAAATTTAATGAAATATCGTTATGACTATTCGAAAAAAATTTCATTATGGAGCCCGTAAATCGACACAAACTCTATGTCCTGTAGTCATTTAAAGAATTACTGTAGTTTTCGTTACGAGATATTGTGCGCGTTGTCCCCGTAATAGTTTAACTTTTACCACGTGGTCGCCAGAAGGCAAGAACTTCTGCTACCGGATTTCATTTCCTCTGCCACAAACCCTTTGGACCCCCAGTAGAAAAAGTACATAAAAACAATTCCGGGGACTGGGTCTCCAATCTCTCGCCCCCACTCACTAACAAGGGGGACACCCTCAGAAACGAATGCCGTCTAAACGTCTGCACCCTCTCTCTCGTCGCTCCAAATTCTTGGATCAATGCGAACTAACACGCAGTGACCCCCCTCCACCTTCATCCACCCAAATGTTTCATCAGTTCCCGGCCACCGCAGGCTTCTCTCTCTTTCTCTAAAGCTCTCATATAACTACTGTCTCTCTCTCTCTGCTTCTTTTGCTCAATTGTTCTTCTTCATCACTACTATTTGCTCAATTTTCGTAAAATGATATTTTATTTTAAAATATTCATTTTTCCTCCCCCCGCCTCTGCTTTTCATCGCTTGACGCGCCACATACACTACAAAAACCGGTTTTTTCTATCTCTTCCGCCCGATCATAGAATAGATAGTGTGTGCTGTCAAATTTCCATTTCCTGGAAAAATCGCGCCGAAATTCCAGAAAATTCCACTTTTTCTAGAATTTTCAGGTCGTGCAGTTTTTTCGGTTTTTGAATCTAATACAAGGCGAATTCCGTGAAAATTAATTTTTCCTCATTTGACGAATAAAAAATATTAGTATTGTTTTTCTTTCAAGAACGTGTGATTTTTTCACAATCTTCTATGGTTTTTACGTGGATCTTGAACTTCCACAACTTGACAAGTCTTTGAAAATTAATAAAATTTCACCGTATCTGCCGATCGTTGCAAGACACACTCCACATAAGAAGTCGTGCGCCTTTAAACTGTGTACGGTAACTATAGGAAACTGATTTAATCCACTTTTTTCTTCGAGCGCTTTATCCGTCTATTTTTCCAATTTTTCCTCACTCTGATTTCGAACGATTTTTTGCATCTTACCTCAAAAAAATTAATTAAATGCATAAAGTGGAATTGCTGATTCTTTACCAAAAAAACACTTAAAAAATCTTCTCATCAATTTCAGTTCTTTCTGGCATGGCTCATTGTTTATCGACACCTGCTTGTTTTGCTCCGTAACTCCGCTCCCAAATTTTATGAGTTTTTCTTCGAAATTTCTCCATTTTTCCCGTGGTTCAAAAACCGCCAAAATTCGCTTTTTCCAGAATTCGCCTACTAGCACTACTAGATGTGTTAATTTGGGGCGGAATTATTTTACAAAAAGCAATGTATCCGGTTGTACGGGCTTACTGAAAATGAGAAGCTCAAAGACCTTGAAGGAGCTGTGCATATGGTCAATATATCCGATGAGGATGCCATTCAATTTTTAAAAGGTGGATAATTAAGCTGAAAAGTGGAAAAAAAAATGCATTTTTTACTTCAAATTGACCTAAAAATTGGACTAAAACGTCATAAAATTACTGAAAAGTCAGAAAATTGTCTAAACTTAATTTTCGCTAAATAATTCCAGAAAAGCCGACTGGGACATTGCAATGTCATCGCGAAGAGTGTTTCCGAAACAAATGAGGATAAAACAAAGTGTAGGTTCCGGGCACTTCGAGAGGTAAATTTTTGAAAAATTTCAGAATCAAACTGAAAAATAGATATATTGTGTGAAAAAATGCTACCATTTTCTCCGTAAAAAGGGAATTTTGACCGGTTTTTCAAATTTTAAACTGAAAAAAAAAATTATATCTGAAATTTTGCTCTTTTCGGCGCGTTTTTTCTCAAAATTTGATGAAAAAGTTCTAGAAAACAAAAAAGCCTTTATCAAATGTACTTGTTTCTGCGATTTCTCAAATTTAAAATTTTACGCGTCAAATCTGGTGTTTTGACTCCGCCCACTAAATTTAAACCTTTCGTGAAAAAACAATGTTTTTCTCCGATTTTTAATAATTTAGGCAAAAAATATACAAAATTTGCCTAATTCACCTATTTATTCCAAAAAAATATCACAAACTTCCTGCGCGTAAAATCGGGTGTTTATGCTCCGCCCACAAAAATTTCTTAGAATTCGAGTTTCGGCGGATTTTTTCTCAAAATTTCATGAAAATTGTGAGAAAAACTACAAAAAGTCTTTGAGCTTTACTCTTTCTCTGCGATATCTAAATTTGAAGATTTGCGCGTCGAATCTGGTGCCTTGGCTCCGCCCACAAAATTTGAATCGTTTAAAAAAATGTTTTCACCACTTTCCCCGCTTTTTCGCCTGACTACCAATCCCAATTTTTTTGCAAATCGATTTGGATTGATTATCGTGTCGTCTACGTGTTCTTAGCCTTCTATCTTCTAGATTTTGGAGGTTTCCCTGATGAATGTCGAACGTTAGAAAGATTTGATAGAGACGCAGACACAGAAGAGCCTTGAGTCGCGCGTCCAGTAAGTTGTTTTCTGGAAAAATTGTAAAAAAAATTGAATAAAAAAAATGATATTTTTAATCGAAAAAAAAAGTTTTCAAAAATCAAATTGGAAAAGGTGAAAAAAATTCAACAATAAAAAAAGAGCGACAAATGAATAAAAAAAAACTTTTTTTTTTTCCAAAAAAAAGAAAATGACCAAATGTTATTTAATCGCCCGAAAAAATAAAAAACGAAAAATGAAAAAGGAAATTTTGTTTTTACAATTAGAAAAAAAAAATTAAAAATGTATTAAAAATTTTTTTTTGACATTTTCTTTCGCTTTTTAATAAGTTTTGACTAGCGGGGCCTGCGGGCCCGCCAGTTGGGGTGTAGATCGGGCGAGTCCCCCAGTCGGGCGTATGTTCTCGTCTTCGCCTAGAACGTCAGAGGATTCGCGACAATTGCAGTGAGTCAATGGGAGGGAGACCCACTCATATTTTATAAAATCGAACATTTGTATTTGAATCCCGAGCACTCAAAAAAAAACGAAAAAGGTGTTTTGTCTGTTGGGGGAATCGAGCGAAAGAGCAAATTATTCACAGCTATACGCACTAACCAGCCATGCGGGAGAGACCTCTCACAGAGATGTAGGGAAGGAAAATTTCTGGGGGGAGCGCGGGGGGGGGGAGTTGTCTTTCGCTTCCGTTTTATTCAATAATGACAATTTGGGGGAAGCCGTTTGAAATAACCGTTTATCACTGATAAGTCAGCAGTAAACCAATTTTTTGAAAGTTTTTTATAGCATGATTGTACTTATTATTTAATTCCCGAAAGAGAGCCGAAAAGTTGAAGGTGTTATCTTGTAAATTGTTTTATTTGAAGAAGAAACCAGTTTTGGCTGAAAATTTTGAAAAAATAATATTGGCAGATCGAGCATTGCGTAATGCGACGAAACTCCAGCTTCCAATTGATAAAATCAAAAACTATGAATCTGAAATACATTGCGCAAAACGACTTTAGTGGACAAAATTTTCAGCAGATAACCGAGGAAACCACTCCCCCCAGTACTAAATTGAATTATTGTTTCTTGAAATATTTTCCCACGGAACTTTTTAAATTTTATATGCTCTCGATGCGTCTTGATGAGACCTACACATCAATTTTTGGAAAACTAAAAAACTTAAAAACTAACCGCTTAGTTATGAGTGAAAAAGTAGATTAGCAATGGGAAAGTGTGCAAAATTTGGCACTTATTCGTCTTGCTCGGCGGACTCATATTACTTTTTCCAATTCTGCGTTAACAATCGTGTTCCGTACTTTTGTACGTGGGATAAAGATAAAATATAAAAGATGCAGTAGAACTTGAGACAAAGAGGAAAAACTACTTTTTCGGAAAAAATTTTTTGTTGGCAAAATGGCATTTTTTGGCCTTTAGGTGTTTTAACACAACTTTTTAGCCTTTTGCCACTTATGAACTCAAATTTTCTTCTCACTCGCTCAAATATCCACCTCCCTGATTGTAGTATCTTGCACATAAATTTAACAAACCCGAGCAAAACCCGAATTTTTCAATTAAAACATGGTTTTTTGGGGGTAAAAAAAGCAACATAAAATTTTTTCAAACGGGGGAAAGCCGCCCTGAGCTCAGCTTTGCTCCAAACTTTGTGCAGTTTTGCTCCGCCGTGGGGTGAAATATTACTAGTAAGCTGTCTAATATTACAATATTCAGTCAAACCGCTCTGCGAGTTATTAATGAAAACGCAGTGTGACTTTTCGCAAGCCTAAAAAAAAAACGCGAAAAAACGCGAAAAAGGGGCGGAGTCTGTACACTCGGCATTTAGTAGAGACTGCTGGCAGATTTTGAAATATCGGAAATACTTTAAAAGTTCGTTTTTTTCCACGACACCTAAACTGGTGGCATCATGTTGATTCGGCCAAAAACCCGCTATCAACTACTGGAGAAGGAAATTGCCTTCCTCACGTCGCATCGTTAGGTAAAAGGTTTTTCAGAGGCGAAAAATCCGAAAATCGCTAACTTACTATTTCCACTGAAAAAATTGTACGCCCTTCATAATTTCACTATTTTCTGAATTGAAAAAGACGACAAAACTATTTCAAAGCTAAAATTGCCCCGAAAATTGTTTTTTTACTAAATTTATTTTGCTCGGCGAAGTGCAAAAATAAATTATTGAATTAAATCTTTACATGTAATCTTCAACAAAATTTAATCGTAAATTTTCAGGTATGTGGGGAGTACGATCGTCCTATCACTTCGTGAAACTCTGTACCTACGAACTTCTTACATGGCGCCAGAAAAGAAGCAACGACTGCGGGAATCGGTTGACAATCATATGAATCAGGTCAATTGGCGGGAGAACAACCTGTGAAAAATTTCTTAAAATTCGGAAAATGATCAAAAATGAGCTGAAGACCGGTCACGTAGTTGAAATCCGCGGAAAATTCCCAGAGGAAACAAGTTTCGGTCAAGTTCGCTTGAATTTTTCTCAAAAAGCTCGAGTAAAAACACGGAGTTGAAATCCGCAGAATTCGAAATTCCCACAGGAAGCAATTTTCGTGGATTTCAACTTCGCGAATTTTGCTCAAAATGCTTCAGTAAAAACTCACGGAGACATGTGAAATCCGCGGAATTCGAAATTCCCAGAGAAATCCTAATTGTAGATTTCAACTTCGCGAGTTTGTGTTCCCAAAAAGCTTGAGAAAAAACTCACGGGGTTGAAATTCGCGGAATTCGAAATTCCCAGAGAACACAATTTTCATCGTAGATTTCAACTTTTCTAGATTTTTAGCCAATTTTTTATTACATTATGTTACAAAAAAGCTGTAAATACTCACGGATGAAATCCGCGGAAGTCGATTTGATGTTGTAGATTTAATCTTTTCCAGAATTTTCCAACAAAATACGTTAACCGGAAAGAATTATTGCCGACACTCCAGGAATCTAGTTTTCAGGAGATGGCTTTCAACGTCGAGAACTTCGCACATTTTTTTGCATTTTTAAAAAATTTCACCAATTTTCCAATCAAAATTTTTTAAATTTCCAGAGTAACGGTCTCGCATTGACCCGTCTCTCGGAAAATGAAGAGTAAAAACTCACGGAGTTGAAATCCGCGGAATTGTATTTGAAATTCCCAGAAGCACAACCATTCTCGTAGATTTCAACTTCGCGGAGTTTTCGGTCAATTTTTTGAGATTTTTTCTCAAAAAGCTTGAGCAAATACTCTCGTAGTTGAAATTATTCCGCGGAATATTCCAGGAAATTCGATTTTCGTAAATTTCTTCTTTCCCAGAATTTTCCAATTAAAAAAGAACGGAAAAAATTGTCCGACATATCCTCCATGGACTTTAGCTTTAGATTTCAACATCGAGAACTTTTCTCGTAGATTTTTTTGCATTTTTTAAAAATTTCACCAATGTTTCAATTAAAATTTTTTTAAAAAATTTTCAGCGTAACGGTCTCGCATTGACCCTGTCGCGGAAAATGAATGGGGACTCGAATCGGATCGATGTTGTACTCGGATAAAATATCATCTCAGTACCCCGTAAACAAGAGGATAATGGCTGGATTCAAATTCCACAGAATCTACGAGAGTCTTGAGGCAATCCACGAGAGGTGTTCGCGTTGGCTCATCTGCTCTAAAGACCAGTTGTGGTTGTATCGGACACGGTAGGGAATTTTCCATTAAAATTTTTTCTTCAAAAATTCATTGAAGAGAAGCAGTAACAAAGAATTTGGTTAATTGTGAATTTTACAGAAATATAGAAAATTTTAATTTAAAAAATTTCGAGATTGGTGAGCAAGGGTGTCAAGTCCACCCGTGTCCCGTTTGTCCCGTGGTCCCGTTTTTTGAGTGTTTTTACGGAACTGGACGTCTTTGGTCCCGCTAATTTTTGAGCGTTTTCACGGGAACGGGATGTCCCGTTGTCGCGTTTTTTGTTTTCGCGGGAACGGACGTCCCCCCGTTGTCACGCTTTTAAAATCTGGTTTTGTATCACGGGAACGGGACATCCCGTTGTCCCGTCTTTTGTCTTACGGTAATATTGACACCCTTGGTGAGAATAAATCAATAATACACATAATTTTTGGAAGAAAAAACGATTTTAAAAATGAAGCTTAACATTTTTTTTCGAAAGAAAAAAAGTGTAAGAAGTTTAGCAAAAAAAAAATGAAAAAAATATCTTCAAAAATGTTCAATATTGTTTTAAGGTGCAACTATTACAAGAGCACACAATTCTTAGAATACGTAATGCGCTACCTATTTGACGCGCGAAAGCTACAGTAATACTTTTATTGTTTACTGTAGTGACTAGCTTGTGTCTAGATTTACGACTGGAGCTTGTGCAGATTGATAGAATATTCAAAGGGATAATTTATTTATCGATTTAATATTCAAATTAGGCAAAAAATGAGAAAAAATATACATGTGAAAAAATTATTTAAAAAGAGAGCTCGTAAGGCATCGACACACTAGTACATTTAAAGGTTTACTGTAGTTTTCGCTGCGAGATATTTTGCGCGTCCAATTTGTTGCTTAATACGCTTTCTTAGAATTTTCACATAAGACGGGTTTTCTAGGAAAAATTTTAATTCTTCATAAAATTCGTCAATAATAACTAAACCGTTAATCAAAAAAAAGTTTTTAGGGTGTCATCAGAAAAAGTCTCAAAAAAAGGCGGTCATCAAAAATCCATCAAAAAAAGAAAATTGAAAAATTTGAATTGAAACTTTTTCGAATTTTTGAAAAAAAAAGTGTTTGAATATTAAACGTAATTAAAAAAAAAGATTTTCCTTTTTTAGAAAATTCTATTCATATTAGAACAGTCGATTTTATAAAAGTATCGATTTTTTTCAGAATTAATTGGATTTTTTGTAAAATAATAATCGATATTGAAAATAAAGACCTTTCGCCTTAAAATATTGTATTTGACAGAAAAAATGGTGTAAAAAATTTTTACCAAAAACCCTAAATAAAATTGCAAATAATTTTCACCTACAAATTAATTGTTTATTAAATAAAGTTTAAATAAATTGCAAGAACAGGAGTACGTGTTTTCAAAATTATTCTTTAAAAACGCGGGTTCTTTTAATTCAGAAAATTCTTTTACAAAAACTCAATAATTACGGATTTGTCAAAAATTCGGATAATTTACCAGGAAATTCAGAAGATTTGGATAACATAATTCTAGTTCACTTCCAAAAAAATGATATGCGACTTACTTAAGGTACAACTAACATTAATTTTCCAACACTTATGCTGCTTAAAGACACGCCAATGGGGTCAAAATGACCGAATATTATGTTTAAACAAAAAAAATTTTCTGATTTTATATATGATTTGAAAATTGGAAAAGTAACAGTTTTAACCTAATTATTTTGAAGTTCTGCCAATTGGATTTGTTCGGTGCAGCGCGCTTGCAATAGTTTCATTTATTTATTTATTTATTTATTCTCGTTATTTCACGGAGGATTTTGCACTTCCATTTTCGATGTTTTTTTTTCTCCGAACGAATGAAAGAAATAAACAAGACAAATGTGAAATGGTTGTTAAAAAGTAATTGAAAATGCTTATAAAACTGTGATATTCTTAGTTCGACGAAAAGACTGAGATGAGGATATTTCTCAGTGTCACTCATTTTCAATTACTTTTAAACAAACGTCATATCGCATTTATCTTTTATTTCTTCTCCCGATTTTCTGAAGAAAAAACATAGAAAATGGCAAGAAAATCAGTGAAAAAACGAGAAAAATATATATAATTCATTAAATAAAAATAATGCAAGCGCGCCCCTCCACCGAACAAATCTAATTGGCAGAAATTCAAAAATAATTAGGTGAAAACTGTGATTTTTCCAATTTTCAAAACGTAAAATAATATAAAACCTAGAAAATTATTTTGAATTTTTTTATCATAATTTCCGGTTATTCCCATGGGCGTGCGTTTTTAAAACAATTCCCACTGAGCGTAGACCTATGTTCTCAAAAAATGAAAACGAGTAATACTAATTATTTTTTAAAAATCCAATAGTGTTTAAATTTTTTTTTTGCAGATTCTGCGAAACGCGGGGAAAGGCGAAGATGACTGTCTCCAGTGGCTTTTGGTGGAAAATATATTCCATAAGAATGCCCACCATCACAATGTCATCGATGACGACTTGTTTTATGCTATGATTCTGCTCATTTCTCACCGGACTATTGTACCATGAAAACAGAGACTAACAATAAACTTAAGGAGTTTTTTTATATGAGCAAAAATATTTTCAAAATCTTTTAACTGAATTTTCAAATTTCCCCCTAGCCACCGGCCCCCCCGTTTTTTTCGAAAAGTGAATTGGAATTTTCGAAAGTTGCACAAATTTTTCTTTGAAAATTCAAATGTTGGTCAATTATTTATTCGAAAAATCGACATTTTTCCAACTTGTAATCTTTTTATTCTAAAAATCCCAATTTGATTTGGTAAAATTTCTGTCAACAATCAATTAAAAATCCAACATTTTCAAAAAAATTGTGAATGTATTCGGGAAATTCGAAATTTCCTATTTATTGGATAAATAGGCTAAAAGTTTTCGATTTTATAATTTTTAGGAAAAGAAGTTGTCAAATTTTTTTTTATAAAGTTTTTTTTTGAAATTTCACTAAATGAGCCAAATTTTAACAGTGGAGCACCGAAATTTGCGACTTTGCTTTTTTAGACTCAGGATCCAAAACTAACGAATTTTGTAATGATACATCTGACAATTTCTCAAAAAAAAGTTATGGCTGTTTAAAGTTCGGGCAAAATAAGGCCCATTTTCAGCTAAAATCAAAATTTTTTCCAACTTCTAGGTGTCGCAACGTCTGATGGACCCTAATTTTTATCTATTCATCACTTTAATAAATATTGTGGCCTTTGATTGAGCATTTAATCGTTGTTTTAAGTTCATTTATGATCTTTGGAGTACAAATAAACGTTACATTTTGTACCACCAAGACCATAAATGTATTTAAATCAACGATTAAACGCATCATCAAAGACCACAATTTATTAAGTAGAATAAATTAATGCGAAATGTTCCACACGTCTTGCGGCACCTAGCCAAGTTAAATTTTGATTTATTTTAGCTGAAAATGGGCCTTATTTTTCGCCGAACATTGCCATAACTTTTTTTTGAAAAATTTTCAGAACGTTTCATTACGATATTAGGTAGTTTTGGGCCACTTGGGTCTAAAACAGCAAAGTCTCAAATTTCGGTACTCGACCTTTAAAGAATTCATATAATTTTCTAAAACAACATATATTTACACAAATACTTAATTTAGTATCAATATGAATTATTTGAAAAATCAAAAAATTTATATGTATTTTCAGAAAAAATTCCCATGATCGATGTGAACCGTAACCTGCTGCTCCTGTCCATTCTATTTACAGTTGATCCAGGAGAGTCAATTGGTCCAAATAGAAACAAATAGTAATACACAGACAACTACAGATATGTCACAAATATGGGTGATAAGCTTGCGTTGATGTAAGTCATATGGATATTGTTAGGTAAGAAAATGAGAAAAAGGATTTTTTCAATTTTTTTTTCTAAATAAAACATTCAATATATCGTTAACAAGCCAAAAATGTGTACATGTTTTAGTTTAAAAAATATTAAAATTTTTTAGTCCCAAAATTAAAATATCGAAATCAAAGTGTTTCCGACATTTATATAGACGAATTCTATTTTTTTAAAATCGAAATCATATTTTTAATGAAAGTACAGAAAACAGCGCCAAAAAAGAAAAAAACGTTTTTTTTTTTCGAATCTTTCATTACAAATATTTGAAAAAACGAAAACTACAATTATGGGAATTTCGCGAAAATTTTTTAAAAAAACTTTAAAAAATTCTTAAAAACAGCTATATAATCACGAATGAGAAATATATCGGAAATCCGGAAAAAATTAAAAAAATTTTGTGCGTATTTGTCTGAAGTTATTTTACAAACACCAAAAATAAATCAATTATTGTTGGAAAAAATTGAAATACAACGGAAAACGAATTATTTATATTTAAAACGAACTAAAAAAAATCCCGCATCACAAAATTATTGGAAAACGAGAAAGCTGATTTTTCGCTAAAGTTCAAAAAAATTTACAAAAAAAGAAAAAAGTATTAGAAATCGGTAATTTTCCGAAAACTGAAAAATTCGAGTTTTCTAAAATAAATTAAAAAAAAAAATCAAATTCCACACTTTTGGAAAATTACGGAAAAAAAGATGTAGTTTTCTTTAGCTTTCAGCCAAAATTTTACATAAAAATTTCCGCAATGCATAGTTTTAGAGAATAATTTTAAATTGAAACACTAAATTTTTTAAAAAACTTGCGTTTTTTTTGAAAATCCCCGAATTAAAAAAAAATAAAATTTGAATTTCAAATAAATATTTTGCTAGCAAAAATAGTTTCTAAAACAAAAATTTGAAAAAAAAAATATTTAATATTTATTTCATATCCTTTGATTAAAAAAAATCTAAAGAAACATTTCAGACTAGACGTCGTCGTGGCTCAATACGCAGCTCGCGGAGAGTTCGAACGTGCTCACGCGCAACTTCTCACCGAATCTCGTGGTGAAAATGGGCAAAATTTGCCCAAAAATTAATGAAACCAAGAGAAAGTGCACATTGTTCTAGTGATGAACAACTATCAAATAATGCAAAAGGAATCACATTAGCATCAAGTGGCATTGGTTCTGGAAGACATGAGAAATGGAGATTAAGCAATAATTAGGGAAGCATTGTTTTTTTTTTTGGCCTAAAAATTTTAATAAAAAATCTGCTTGAACAGAATTTTTGAATCTTGGAAATAATTAAAAAAAAATGTAGTAATCAATTTTAATTTTAAAAATTAGAAACTTTTCAGATAAAACATTTTTATTTTTTCAAAAATCAGAGTTTGAATCATTTTCAGAATAATCATAACGTAATGAAATCAAAAAATTCAAACTACAATACTACGGTAACAAAAAAAATCAGAATGCGTACTACGCAACATATTTGACGCGCAAAATATCTCGTAGCGAAAACTACAGTAATCCTTTAAATGCAATACTACTGTGTCGATTTACGGGCCTTGATTCTATTTTTTAATTAATTCATTTTCGAATAGTGACAGCCATATTACATTTTTATTCTCTTCTTTTTTGTATTATTTTCCCTTTTCTTTTGCCTAATTTGAACAGTCTATCAATCGAGCCCGTAAATCGACACAAGCGCCACTATAGTAGTCAATTTTAATGGCAGAAGTACTGTTGTTTTCGCTACCAGATATTTTGCGCGTCAAGTATGTTGCGTAGTACGCATTCTCAAAATTTTGTGTTCCAGTTATTTGGTAGTTTGTGAATTTTTTTAATTTTCATTAATGATTATTCTGAAAATGAAACTCTAAGTTTCTGAATAAAAATGTTAAAAAATTTATTTTAAAAGTTCCTCATTTATTTAAATTAAAATGGATTCTTTTAATTTCCAAAATTTGTTTACAAAAAATTCGTTTAAAATCGAAAAATTGAACTGTTAAATTTAAACTTTTCAAAAAAAAAGTTCAAAATTTTTCTAAAGTAAATTTTCAAAATGATACATGTAATTTAGATTATAATTTAAAAAGACAACCAAGACAAACATTTTTTAAAATATTAAAATTTTGTAAAATATACAAATGAATGTTTATCCGTTAAACGACTAAGCCTTAAAAAGCCTCAGTCTAAGCCCAAGTTTCCAATGCCCCTAAGCCTAAGGTCGAACTGCAGTTTTTAAAAAAAAAGTCCCAAATCCGCTTTCCTAATATTGGTACCAAACCTCTTATTTGCCAAAATGAAGAAAATGTTTTTAATTTGAAATTTGTTGATCTGAAAAAAATGTGAATTAATTGCCTTTGTCGGCTGGATTTTTTTTTTGGAATCTATTTTAAGAATAAAAATTGATTATCTTGCGTTTTAAACTTTGATTAGGGTATTTTAAATTCGATGGACGGCGAGTTTTGGTTCAAAAAAATTAAAAATCTCGCCGTCCATCGATTTTTAAATACCCCAATCAAGTTTAAAACGCAAGTACTTAACTTGCATACTCGAAAGTTGACGATGTTCAAAAAAAAATCGTTTCCAGCCCTTCGACATCGATAAGTTGGTCAAATTTCCGATTTCTTATTTTAGGCCATTGTTTGAGCCGTCATAACTTTAGTTTCCGTGATTTCAAGAACGCGTTTCATTATTAAATTCGGTGTTCTCGGACAATTTTGAGTCTACGAAGCGAATAAAACGACTTCACCACCTTTAAAGCTCAAAATAAACGTGCACAAATTTAATTTCCTATACAGAACCCACGGGCTTCGAACTTTTCGTAATTCCTCATCAACACGTGGCAAAGAAAAACTAATCGATACGGACGATCGTATTGCAAGAATGAATTCGACGTGCGTTCTTCGCATCGGAATTATTGCCAACTCATCACCAATACATGGACAAAATGAATCATACTTCGAACGAAACAACGTGCATAATTCCAACAGAATCAACGAACACAATCGGATAGTCGGAAACGGATTAGTCGAAGTGTCTGCAGTGCAAGCTCACTAATGCTCGTGTATCGGTTGTGATTCGGTACGGGACCTACTTTTTGATGTGAATTTCGAGAAAAAAATTGTCAAAAAAAACGGAGAGAATTTGGCACAAGTAGCCTCAATATTTGAAAGAAAAAACCGAACAAATTGATGAGGGGAAGCCAAAATACCAGAATTTACACCCAATCTAAAGTTTTATTGATTTTTTACAAAAATTTGCTCAGTTTTTCAGTAAATTTGCCAGATCTGACCATTTTACTATTAGGAACCGTCATAATTCTGGGTTTTGCCAGACAACTTCCTGAAAATTTAGAACTAATTAATTTTTAATTTTTTGTGGGGGGATCATGTTATTTCCTAACAGAATACTTTGATTTGAATTTCGAAAAAAACCGATTCTAAGCTTAAACATTGACAAAAATAGCAATGAATGTCAAAGAAATTGCTAATACATAAAAATTGTGAAAAAATACACAAATAACAATTTTTATTTAAACTCGTCATTAAAAATTTTTTCAAATTTTAAAAAATTGAAAAAATAAAAAATTTCTAAATTAAAATTACTGTAAAACATTTTTTGTTAAAATTTGAAAAAAATTCTAGAAAAAAAAAATTTGCATTAAATTTCGTTTCTTCAAGCCGGCATCTCAAGTTACAAATATCAAGTGTGATCAAAGTTTTGCTTGGCACAAAATGAGTGTTCTCACGTCGAATTGCGACCAATTTATGGGAAATGCTGGGCCACCGTGCAAAATTTCAACACTCCCGTCATTTGGTAGTAATGATAGTAATCAGAATGATAAGGAAAATATTGTGGAGGTACTTAACGTGGTGCCTAAAGATGGAGCCAAGACACTTACCAGGTATGGGGATTTGAAATTTTGAAAAAATTAGAAGTTTCAATGAAGACAGAAAATATTTTAAAAATTTATTTTTAATTGAAAAATAAAACTCCCAAAAAACAGTTTTCCCAAAAAAAGTGTTTATGTTATTTGTTTATAATATTTACGGAATTGATTTTAAAAATTACGAGAACACAAAATTTGGAGAATGTGTATTGGTCGCTACATATTTGACGTGCAAAATGTCTCGTAGCGACAAACTACAGAAATCCTTTAAATGGCTACGCGCACTAGTGTCGATTTACGGGCTCTATTAACGAAATGAATTAAAATGATTTAGTTATCGAACAAAAATCATTTCATTAAATCGAAAATCAAGCTCGTACATCGACAAACAAGCTACAGGAATAGTCCTTTAAAGGATTACTGAAGTTGTCGATCCGAGATATTTGCGTAAAATATGTTGCGCAATAGCATTCTTTGAATTTTGGCTTCTCGTAATATACGAAGGATGAAAATTTCAGATTTTTAACAAAAAACTTGTGAAAATAAAATTTATGAAAAGTATAAAAAGTTGAAACAGAAATTTTTTTGAGAAATATCGATGTCAATTTCTTCACAAAATTTTTCAAAAATCGATTTTTCTTTCGAAAATTTTTTTTTGTAATTTTAAATCAAAATTTGGCGATTTTCAAAATGTTTATTTTATATTTAATTTCTAAAATTAATTATTTTTATTAAAAAATATATAAACTCAATTTTAAGATTGTAAAATGAATTTGGTATGCCGTTGAAAAATAGAAAACTTAAAATCTTTTTAATAACTGACACAACTGAAAATGTTGTTTGAAAAATTACATTTTTGCAAATCGAACATTTTTGACGCGCAAATTTGTAAAAAAAAATTTTCCGATTAACAGAATAGGGAAAACTGTAAAATAGGAAAAAAATTTACCTAAAAAGCGTATGTGCCTTTAAAATGTGCAGTAACCCAAAAAAATCGATTTTTTGCAGTATGCGAGCTGTGGAGGAAAGCGAAAACGGTGTGGAGGAATTCGTCCACTATTATATGGACGATGAAGTAGCGGATTCATGATTCTATTATACCCATCTTCGATTTTTTTGAAAATATCTTTACTAGAGACCAGTTTTCATTTGAATTTTTATCGATTTTTTTTGGATTCCAAATTTTTGTTCTTTTTTTGGGACCTTGCTTGTGTGTTTTTTGCCGGCTGTCCTTCTGTCCTGCCAGCCAACGGTGACCTTTTCTCTTCTTTTTTCTGTCTGAAGAACTCAATTTTCCCGCCTTTGCTTTCTTCGAGATTTTTGCTTCCATTTTTCATATCCGCGCCAGCTTTTTCTCTCCCCTCCAGTTTTTTTACCCATATTTTCGAGCTTTTTTCTGTGATTTTCACCCCCAGAAATTTTTTGTACCAAAAAATTGATGCTTTTTTTTTTTCTCGTTATTTCCAGCAAAATGCTTGGGCAAAGAAATAAACTCTTTTCTAATTTATCATTCAAAATTTGAGACCAAATTGAAATCCCACGCAACTGCAAAGTGGCATTTGACAATGCACAGCATGGCACGCCTTTTCGTCTCACCCGGGGGAACGCGTATTCTGGGACCAGAATGAGGAGGCGGTGGTGATCGGAGAAAATGAAGTATGGACCACATCTGGAAGAGACACCTGATTTTACGCGCAAAAATTTTGAAATGTATCGATATTTTCGGTCAAAAATCAATATTTAGCGATTATGGGCACATGGGCTTCTGGCCTTCCTCATTGAATATTCGCGCTCCATTTACTACCAACTGCCTGCGGACACTGACGCGTGGAAAAGTGTGGTGTACCTCCACACGGGGGCCACAAACATCAGTTACCGCTTACAACTAAAATCGAGTCGTTACGCGACACGCAACTCGCCATAAATCTACACAAAATCTCGCCGACCCATAATGGCGTAGTTCGGCAAACTCTGCCATGACGTTCGAGTTATGAGCGAAGCCAGAAATCCGTGCTATGAGGGCAACGATTGAACAATCTGAGTGAAATCGTTTCCATACAAAATTTTTTGAAAATTTTAGTCTGAAACTGCCTAAAACTCGAAAAGTTATCTATTTTCAGGTCTAATTTCTGAGGAATATTCAAAAATTGCTAATATTCTCGAAACAAAAAATCGGAGCCAATACATTTGACGCGCAAATGTTGAATTTTCAAATTTACAACCCACTAGCGGGATTCTGGCTTCCCTCATAAATCGCAGTGGCAGAGTTTGACTAGGCCATTTTTGCAAGTGTCGGAGAGGTTTTGTATTTACGGCGCGTTGTGTGTCACGTCGCGGCTCGTTTTCACTCAGTTGTAAACTTGTTGTATTTGCCCGTGTGGAGTACACGGAGGACTTCTTCCACGCGTTGGGCATTTGTCAATGGAGCGCGAAAATTCAATGAGAAGGCCAGAACCTCGTGAGAATCCTATACATTCTGAGAATGCGTATTATGCATCAAATCCGACGCGCAAAATATCTCAAAGCGAAAACTAGAGTAATCCCTTCTATAACCCTAATGTAGTGCTTGTGTCGATTAAATTTACGGGCTTTCGAAGAAGTTACTTTTTTAGTTACTTCGTATTTTTTTTCATTTGTCTAATTTTAATATTCTATCGATAAAGGAATGGGTTTTTTTTTATTTTTATTATCGAGCCCGTAAATCGACACCAGTGCTACAGTAGTTATCACTACGAGATATTTTGCGCAATATATTTATAAGAGTTGGCGGGCCCGGCGCGCCCGCCATTTGTAGGGGTGTAAGGCGAGTCCTTGCGTAGGTTGTGCGCTCGACTTCACGACCCTTAGAGGGTTTGTGAAAATTTCAGTAGGTCAATGGGATCCGGTCTTCTTGTTTTTTGAGTTCGGTTAGGACCAAAGACAGATGCACCCGATGGATAAATCTGAGTTTTGATTGTGGAGTTTGGGGAGGCTTTATATTAGGGGTCGTAGACGTACTATTTTGTATAAAATTGAGTATTTCTATTCGAATCCCGATTACTCACAAAAAAACAAAAAAAATTGACACTTGGTAGAATTGAACCAACTACCAAAATTTCTGCAGTCATACGCACTAACCACACGGACATGCGGACGGAGACACCTTAAACTGGGATGTAGGGAAGTTGTTCTGGAGGAAGTCGTCTTTCGATTCCGCTTTCTTCAATTATTACTATTTGGGGAAGACGTTCGAAAACCGTTTTAATCACTGATAAGTCAGCGGAAAACCGAATTTGTGAAAATGTTATCACAGGATTGTACTCATTGTGGAATTCCCGAAAAGGAGACGGACAGTTGAGGGTTATATCTTGTACACAAAGACAGATGTATACAATAAAACAAGTTTTGGCCTGAAAATTAAAAAGAATAATATCTCTTGGCCATTGCTAACGCGCCGAAACTTCATCTTCCATTAAATAAAATCAAAAACTATGAATTAAAAATACATTCCGCGAAAGTGGCAAAAAAGTGTTCAGGGGACCCAGGAAACCACTCCCCCCAGTAACATATTTTTGAATTATTTTTTTCTTGAAAAATTTTCCCACTGAACTTTTTACAAATTTTATGTCTCGATGCGCGTCTGGATGAGACCTACACGTTTTAGAAAACTAAGAAAACTTTAAAACTGATCGAGTTATGATTGAAAAAGTAGATTCTAGCAAAGATGGGAAAGTGTGCAAAATTTGGCTACTTATTCGTCTTGCTCGGCCGACTCATAGTACTTTTTCCAATTCTTGTGAGTTAAAAATCGTGTTCAGCGTACTTAGGTTTTACGTGGGATAAAGAAAGAAAAATATCAAAATAGATGAAGTAGACTTGAGATAAAGACGAGAAAACTACTTTTTCGGAACAAAATTTTTTGGCAAAATGTCATTTTGCCTTTTGTTTTATCACAACTTTTTTCCGTTTGCCGGACTTATGAACTCAAACTTTTTTTCAAAAAATCAGTCTCTCTGAGTAGTATCGTGCACAAGAGTTTGAATCAAAACAGAGCAAAACCCAAATTTTAACTCAATTAAAACATACTTTTGTGGGGGTAAAAAGAGCAACAAAAAAATTAACTGGGGCAAAAGCCGTCCTAGAGGGCTCAATTTTGAGCCTCCTGGAACTTAGTGCGCGTTTTCTGCTCCACTGTGAAAATATTTCTAGTAGGATTTCACAATATTAGAGTGTCATGAAGTGACACGGTTCAGGAGTTGTGAATGAAAACGAAGTGGGACATCGCAAGCTCAAAATAAACGCGAAAAAACGCGAAAGAGGGGTGGAGTCTGTACACTCGGCATTTATTAGAGGCTGCTTGGCAGAACCGACAATTATCAATTATGTATATGATACTATAAGAATTATATTCGAATTTCACGCTTAGGTTTTTAGCAGCATAGCCGCCTGAAGTTCGACATTTAAAATAAAAACACGAAATGTTTAGTACGTGACAGCCAACGTGGCAACAAATGGAATCTCATCGACAAGTCCTTCAGAATTGAATACCATGGAATGCAGCAATTGACGTACGATAAATGACCACGAATTCACGTTTTCAAGCGATAATTTTTTATTGAATGACGTGGTAGTTTGGTGGCACCTGAGCGCTGTTAGCCAAGCCACTGTTGGTAGAGTTAATCGGTAAACACCACCCGTCTCGGTTACTCCACGCTTCTACGCCGCTAAAATTTGGTTTTGCATTTCCCATTGGGTTACGTTTTTGAAACGGGTTAGAAATGTAGAAAATGGGCAAATTCTAGGCCATCAATTTTCCTTTTGCATGTGTGCAGGAAATTGGCTAACATTCTAGAATTAATTTTATAGAAAGTGAAATTTTCGCAAAATCAATAATCCGAGAAATCGATAAACTTTGATAGAATCTTGTTCATCAAAAACAGATAATGTCCGAAAAATTTCAGAAAATTATTATTTACAGTCTCCGTTCATTTCGTGGCCTAGAAAGTTATCGATTCTAGGCTATCGAAGAGTTTTTCCAATTAGATTCACGACCACACGTACATTTGCATGTAACAATTGAGCGCGACAGGCTTATTTGAAGGAAGTCGAAGATCTTCAAATTTTTCGCGACAGATCCGACACTGTGAGCTTTGTCCCGCCGAGTTTGAGTCCTGATGTTCCGATTTGCCATAAAATTAACCTTATTACCATCCTCGGTGCCTGATAAGAGCCCGTGACGACAAATTTCTAGGCAAGTTACTGCTCCGTTGGTTATCTGGAATAGATCGATCATTTGGAACTTGTCGATTTTAAGAAACATTTTAGTGTACTTTTTTATGGGCAGAAAACATTGTTTTTTTTAATATCCCTAAACAAAACTACTGATAATTGTAAAAAGATCAATTTTTTATTGTTTGAAGATCTTTTTTGAGTTCCCTAGCTACAAAATAAACAATTTTAGAGTTGCAAAATTGTGAATTTTAAAAATAAATTGCACAATTTTGCCATTTTTTAATGGTTTTTGTTAAACCGAGTTTTTCTGAATTCAGCATACATGATTTACCGCTTTTTGACATAATTAGACAACGTTTGATATTTGTCCAATTTTTTTCAGCCATCTAATGACTTTTTTTGGGCAACAAAAGAAATTTCCTAAAACGAAACTTCAATATTCTGAAATATTGTGAAATAGTAGATTTTTAGGGCTCGGAGATCAATTTTAAGTGTTATTCTCTGGCTACAAAATGCGGAAAAAAACGTAAAAAAGTTTCGTGGTACTTGTGGATTATACCCCCGCCATTTTCAAAATTAATACAATTTCCAACAATAATTTATTTCTTTAAATTAAACGTGAGACCATTTTTCCTTTTTTGGTTATGCTTAGGAATGGTTTTTTCGCCTGGATTTCCACACGTTCTTATTTAATGAGTTAAAATATTAACTTTTAAAATGGCGGGGGTGTAATACAAATTCCAAAGTTTCTAGGCCCCATTTGCTGGGCCACAATTTATAGGCTACAGTTTCTAGGACTTTCCCTGGGAACATTTTCAGAGTTAGGCCACATTTTTTAGGCCCACATTTTCTTAGCCAAAAATGTACTCACAAACTTAGCAACGTGGCAATTTCATAAAAAACCTCATACCTTCTTCTCGAAAATTATTTTTCGAACACATTGAGATATTTCCGGAAACGTCGCCGAGAATAAAGTGGGTCGATGAGTAGAAATCTGCAGAAATTGCACAAACCGGTAGAGGAATCGAGAAGTCTGAAATTCTTCTTTTTTAATGCAATTTTAATCTCGGACCAATCAGCGTTTTGCCACGTCTTTTTTTTTTCGAACCAATCAGAGTTTGGTGGGCGTGGCTAGCTGCTGATTGCTCAGTTTTTTTACCAAAAGGCCTACCGTAGAAGAAGAGCAAAAGTGCTCTCGCCTGGTTGATGGGAACAGAAGAAAGTTTCATTAGAGATACCGCCGAACATTAACGTTTTTCGTGAAGAGCTTGAAATCATTAAAATGATATTTTCATTTCTGAAATAATTCATTTTTAAAGGTATACGCCAAACCACCGTTTCCTCTTCGACATGGTACTTCTGCACAGTTTCCAGCGCAACTTTATCGAATTTGTGAAATTCCAAAAGCTCCTGTCCTAGTTCACCTTAGAATCGTCACGCACGAAATCGTAAAGGAGGTTTAGGACCTAAAAGTTTGAAAAATATGTCCAAATCAAACTGTGAATTTCTACGCCAATGATGGAAATGCTCGTATGAAAAGCGACGAGCAACCTGTGGCCTATTAATTGTGGCGTAGTATCTGCTGCTCACCTACAAGATGTGGCCTAGATAAAATGTTCCTAGAGAAATTGTGACCATGGCCTAGAAATTTTGGCTAACCGACATAGAAATGGTGGCCGAGAAAGTGTGGGGGCAAAAGTTTTTAATTTTCATTTCGGTTTTTTTTTTCACAAAATGGAGAATTTTTTGATTTTTTGAAATTGAATGGGAAAGGTGGAAATATTGCTAATAACCACCTCTTTGCTAATTGTAATATCCTTTTCCACATTCTCGCCGTACACCATCATGCACAGAATCCGTCTGAACTTCTTTATTTTCTTGAAAGTTTGCCACGCATTCTACGTCTCTGCTTTTTTATTTGTCTCTATCGTCTGCGTCTTCCGACGTCTTATACACTATTTCTCCCTGAGGCGGATAGGTTTTCTCGTGAACTGGAAGAGTATGACGTCTGCCATTATTAGCTGAAAATTTGAGTTAAAACTGCTCTATCACACTAAACACGACGACACTCGTGGCCGCGGAAATTGGGAAACTCGGCCACGTAACTTGGTTAAATTAATGAAGATATTATAAAAAACTTCCGAAAATTTGAAACATTTTAACTTTTTTTAAAAAAAAAACACATAATGTTCCTAAACTGGCTAAATGAACAACGCCGCGGCGGAGCTCTCCCGGTTTTCCATGCAAGCGAGAATGCGTTGAGCGGGCCAACGGATGTCAGTGGAGTAGAGACGCAGAGCAGTTGTATAAAAGGGGCGGCGAAGAAATAAATTTCTATCCCAGAGTTTAATCTGTACAAAGTTGTTTTTAATTACCGATGACCGAGTATGAGATTTGGTTTTCTAGGGCACGGAACCAAATTACGGCGGAGTAACGGTCGGTTGAAAATATCGCTTAAATGTTTTGTTTTTTCTATGAACTGACTGAAAATCCACGAGCGTTTGTTTTTTCTAAAATTAAGTTCTTACAAAAATCACCTGAGTGTTCCTTGATTTGTTTTCGTAACTTTTTTCTCGCCAACTCTTCTTTACACTACGGTTTGACAACACGATAACATGTCTGTTCAGTTGAAAGACTGACAAGAGTCTCGTAGTCTCTCGCGGACTAGCTGACGCCCTTGTGGTCTAGAATATTGAAAAACTTAGTTTCATTATTCCGCGAAATTGGAAAACTCGGCCATCGATTTTTTTCCCACGCCCTGGGGCAATATGCACTAGACCTTTCATTGTAACAAATATTTCAAAACTAAGAATTAAAAAAATCCGCTCCTACGCAATCTCCCCAGTCTTGGCGGACGCTCCCTATTTCCAGAACCTCATTTGAATAACTTGCTTCTCCCATGTGTTTTGGGATGGGATAATCTCTTTTTCTACCAATGTTTTCTCCTTACTTCTGTTTAACGGCTTTTTTTCATATTTACTGATTGAGAATAGGTCAAGTGACGACGTAATAGAGCGCGTCGAAGAGGAGAGACGCGTGGCCTAGGAATCTCTGCGATCACCACATGAAATACGTTTTATTTTCTAGGCATCTCGACCGTGCTTTGTCCTTCTATGTTGACAATTTTTTGCAAGTAAATTCCCGTCTGCAACAAGGACACCGCACACAACACAAAATAGGTGAAGGTTCGATCGGATCTCTTTTTTTCCAGAGTCAGACAACCAACACACAAATGATGTGGGTCTCTTCCATTTTCCGGTCGTCAATTTGTTCACTATGCGCTTCACTAATTCCTGCTTTGCATTTCAATGTCCGTGCCCTCTCGGGACTGGAACTGACTTTCACCAATGTTTCTTTAGGTGGAAATTTAGATTTGGATAATTGCTGGAGCCAAAATTTGGAATATTTAGCGACTTGACCGTGCAAAAATTTTGGTGGCCGAGTTTTCTCTTTGCGCCGGCCACGTTGAAATAGTCGCCAGGTGCAAGTTTTTAAAACGACCGAGTTTTCTCTATTGCTTGACGACCAGATCTCGCTTCATTATAGCTGTCCGTCTTCCCACTTGCGTAAAAGTGCGACGTGGCCGAGAATAAATGTCAGTGGCCGAGTATGCGACATTTTTTTAGTTTTTTAGGAGGTGCGGCCTAGTTTTTTAAAACCATTGTTTATCTCCACCCAATCTAAAAAAATTTCTGCGGATATTTTAAACCATGGCCGTAAAAAAAAGCCACTCTCATATATGTTTTCGACACCTTTCGGTTTTAGAAATATATTTTTAAAAATTAAATAAATGGCCGTTATTTGAAATCCAAATAGAAATAATTTTCCAAAAAAAGTGGGAAAATTGGCCACTTGAAATTTTTTCCGAGATCTTTTTTGCGAAAAGATTTGAGGCCTAAAAAACAAAAACTCGGCCAGTATTTTTTGACCTTCCATGTGACGTCACTTGTGACTTACAATTCCTTTTCTCAAGTTCCTTATGAGAAATCGTTTTTTTAAGACCTTTTGTGACCCTTTTGTTGCATTTTCTCCCAGTCGGAAATTACGCCACGTGGAAATAGTACGGCCACACTCTTATTTTATTCCTTTGGCGTCTTTTGGGACAAAGTAACAAGTGAAATTCAAACCATGTAAATTAGATAGCCTAGACTTAGCGACTAAGGCTTGTTGAAATATTTTCGTGGTGTGGCATAGAAAAATAAATATTGGGCCATTCCTTTTTCTTCTCATAGTTTTGTCAGAAGACGTCACTGAAACCTAGAAATCTCTGTTCCAGGGCTGCAAATGGGTATATCCTCCATACCTTCGTCACAGACCGGGATCTTCCACGTCATCGACCGCGCCGAACATTGCATTTTGCTAGAGATTACATGGACCACTAAGGTAAGCTGCCTAGAAAAATAGAAAGTTCGGCTCTAATCGATTGATGATGTTCAGTTAAAAACGCGAAAAACTGCGGACGGCGAGGCGACGATATCGATTTCTCCGAAATTCGCGTGACAGTCCACCAACTTATTTCGTTTCAAGGGAATATTCGAATTCATGCCACTTCTGAAATGGTAAGGCTTGTTTTTGAGGTAGGCCACGAAAGCGTATGGTTGCTTTTAAACACGGGCCGCGGACTGAAGTATCAAACTCGGCCACCAAAAATTGAAACTGTGAGTCGCCCTGATAGAATTTTTTTTTTTCTCGGCCAAACAGCAAAGGCCGACACAGTGAAGTTAAAAAGGGAGGGTGCATTTTTTTAAATAAAAGACTAGACTCCTAATGCAGAAATATCATATTTTTAAATGAAAGATCTAGTCGGCTACGTCCGCGGTCGATTGATACAGTAGTCGCGGCTCGGTTTTCATTGATTGAGCACTGAGAAGTTTCACTTCTCCAATTTCAATTTCAGAACGATGAACTAAGAAGTGGACTACGTGGCAGCCAGTTGACCTTTACCGGATAGATGGTCCTGTAAAGGAGGTGAACGTTATTGCCGAGGTGGGGGCTCTAGAGAAACATCCACAGCATTGGGCAGCCTTCGCAGGTCAGTCCCTAAAGAAGCAGAGACTAAAATGCAAAAGTGCTCTGGTTGTGAGATAACGGATGCGCCCACGAGAATTGTCGAAGTGTTCTGAGAGAACGTGGAGAATATCATCAAAAGCTCCATAATTATAAATATGGAGACAAGACTTTACCCTCAACCTATTTGGAAGACTGACTCATCTCCAACTCCTCGAGCATCAGGCGTTTTCTAACGGCAAACTAAAATGCGAGAGTAAACAGTAAGGCATGGAAAAGGCGATCACGCAAACGGAATTGAAGAATCGAGCGAAGATAAGTGATAAAGAAGACTAAGTATGAGAGTAAAGTACGAAATGATATTGGATGAGGAATCACCGGGAGAAGCTGTGTGATAAACGAGTGTTGTTGAAGGAGGATGATGGTGGATCGAGAAGAGCTTCGCTCTTATGATTTCTCAGTTCAGGGAGAAAATCAACATGAATCTGTGTTGATGATCATATGTTCAAGTCGGAGTGAGGTCTTGATTTTAATTTAATGCCTAAATAACTTTGAGACTGAGGCAGTTCAATAGGCTATATACATATAAGTCTGGACCCAACAAGTTTGTTACAATTATTTTTTCTAGATCCTCGTTAGCTGCTGTGAATCTTCGAGCAACGTCGTCTATCGTTCATGTGTGACAGTCGTACCTAGGATGTTTCTGAAGGGGAAGATTGTGGGCGAAAGACAATGAAGAAGATGATGGAGAAGGGGGCTCCGATGAGGAGGAGATGGAGGGGAGCCTGGTCTTGAATGTGATAAGAGTGATTAGGAGCATGTCCAGGATGTTCTTAGGTCTCCATTAAAATATCGTCGATGAAAAAGCTTAATTTTTTAGATGCTAATTGGCAAATCTATACTTCAACAAAAATAAGTAGTCCTTCCCGAAGTGGAATCATGCCGAGGATTTTGTTGATTTCTTAATTGAAGCGGAGCTTAATGACTTGCCAGTTCTCAAAAGAGCTTGTGAGAGGTATTTGTGCTGAGCTGAATTCGGTAGGCTTCTGTTCAAAAAAATATAAAAATCTAATCGAAATCTTTTCTAGAAAAAAGACATCGGAAGGCACCTGTCCCTGTTGGACTTTTCAACTGGATTGTATTCAACTTGCCTGTCTGGTTATGGAGAAGTCGATGACCGTGTTTGACGGAGTTGGCGAATCGAACGCAAGAGTTTGTGGATGCTGACACACTTTTGGCCCATATCAGGAAGAATTTAAGTGAGTAGGGTGTGAGGCAAAATTGCCGAATTTGCCGAGTAGGGCATATTGCAAAAAAGTAGATTTGCCTAATTAGCCGGGCAAATTTCGAAACACTTAATCACCAGTGTGTAAAGAATCTCAGTAGTTTTGGTGCTCCAAAAACATTAAAAAATATTTTTTCACTTTGTCAAGCACGGCAAATTTGCATTCCGAATTTGTCTACAGGTTCGGCAAACATTAAATAGATTTGCCGAATTTGCGGAGTTCGGCCACGAAATTTTGAGATTTGCCGCACACCCCTGGCGTGCACCGTGAAAAGTTCTTTTTTTCCAAAAATCTAAAACTTGAGGTTTATAATGTGACCCAAAAAAAAAGAAAAGAATTCGCCGCGCATTGCAAAACCATAATCCGCCAAAAGTTTCTTTGTTTTTTTTTCGAAGTGCAGACCGGGTTTCCTAAAGTCAAAATTGGAAACACGACAGGACTTTGCCGAAAATTTAATTTTTGAGTGATCTGTTGATGCGAAAGGTTATTATACGATTTCAAAAAGCTCGGTCACGTGTAATTTTAGAGTGGGATTAGCTATTTAATTACATTTGGGTGTAATGTCCAGTAACCTGGATAAAAGAATGCAAACGCTTTCGGCCGAGAATCGGAATCTTGTGGAGCGCATCGAAATGTGCTACGTTTCGTGACCAAAAAGCAAGAGTTCGCGTTGTACCGACCGCCAAATCATTTGATATTCGGCTTAACTATTCAATAATATTGTCACTGTTTTCCTCTCTTTCTTCTTTCTCATTTTTAAAAATGAATACTTTTTTCTTTTTTTTTACTTTCCACACGACTAACTCCACAGCCGCGCCTTTTTGTCTTTTACCCCTGCTTGCGATTCCACACATTTATCAAAGCTGTAAAGACAGCGAAGTAGGAGTAGTAGTGCTTTTAGAGTACACTTTTGGCAACTCTTTTCTCCAGATATATTATATGCTGTGGATGGAAACTTTCCCAGTTTATATATAATATTATTCATTTTACATATTCCCCTTCTTATACTGCTCACCATCCAAGGTGCATCTGATTACAGCTATTCGCCGGATGGGGCGAGTTATCAAAGCACAAGTGGGGCTCTTTTGTTCATTTTCATTGCTTTTTTCATTTCCTTTCGTTTCAACATTTTTCCATTTTCGAAATTAATCGGCTTTTCTGACCCAGGACTCACGGGAGATGAAAATAAATCTCCTTTAAGAATTGTGCTTTGAAAACAATATCATACAATTCAAACTTGAAACTTCATTTCTCCGTTGTTCCCCGTAAATTCCAAGCTGTCATCCATCAACTCTTTGAATAAAAAATAATCATTTGGTCCGTCCGTCGCGATAAGGATGTGAAAAAAGGTAATACCGGCATGTTGAAATACACATTTCGTCGCGGAGTATAGTTACGCTTCGATTGCTCAAGAGGATTCTTCTTTCCCCTATCATATTTTCGGGCAAAGAAGAAATCTCTGTCACCCCCCCACTAATAGAACAAAATGCAGCGTTCATTTGGTGCGATTTTCCGTTTCAAAAAGAAAAAAGTGTGTCAAAAACCTATCAAAAAGTAACCGCCTAAAGTTAGTTAGCACCTTTTTCCATTGTGAAGTTTTCTTCTTCAAAACAACTACTACAGTTTGTGTGTGTCGTCCTATTGTTGTGGTTGTAATTGTTCGATAGAGCGCGCACAAAATCTCTCGAATTAATTGATAGTGTGTTGTAGTGACCCTTGACTCCTTTGTCAACACCGTAATTAGGAAGGAGTACACCGCCGGGCGGGCGAGTACAGTTATTATAACGGTGGAAGATTTGTTTGTTTACATGTTATTAATAGGTTAGTTGTGTACTTTAAACGTTTTTTATTTGAAAAATATTCTGTTAATTAAAAAATACGTAATTTAGAAAAATGATGACTTTTTTTCACTTTTCAAATTTCTCAAAAACCGAACCCATGGGGTTTATTGACAAAAAATAAGAAAATTTTTCTAGTTATCAAAAAATCTATACATTTTAATATCTGTAAATAGTAAATGTGGAAGACAAAATTTTGACAATGCGTGACTAATGAATTTGAGTTTATTTAACTTAAAGAAGAGGAGTAGACGATAATCAACTATATATTGCGCAACATATTTGAACAATACATATATTTTTCGTAATATTTATTTTGAAAAATGATTGAAAATAAAACACGAAGAAAACTATATTTAAAAACGTCGGTGCTTTTTTTACATCCTGTTTTTAAACGAAAAATGCAAACCAATTTTCCGAGTTTTTTCTTCAAAATATTAGTCCCTGTTCATGAAAAATGTGGCATTCTCACTTATGTAAGTAGTTGTCACATGCACTTTTTGACCAAAAATTATTTTCCGAGTAAACCCTATAATTTCCAAATCCTCTTTTTCTGAAATTTTGAACTTTCCGCAAATCGGGAAAATGTCATTTCAACTCGAATTCATACTAATTATACATCTGTATAATTATTTAGATTCGTACTTTTTCCTCCTTTTGAAAAAGTGCACAGACATCGCCGATCTTTACAACCGTCTGGGCGCAGGACCGGTGTTGTAGGCATTAAATAACTATTTTACCATAAATTTCTTATAATTTTTAGCTGAAACGGTTTTCCAACAAAAAAAAACGCACATTTAAAAGGGTTACCGTATTTCTTCTATCAATATGGCTGCAATACTATTTTTCAATGGTCTTCCCGCCCTTGCAATACTAATAGGGAGAGCAAGACCATAGGGAGTGCAATACTGATTTTTCAGAACATTTTTCTGACTGAGCTTACTATTTTTTTTGCTGAAAAAACTCGAACCTTGTGTGAAAATTCAAAATTTGATTGTAATTGGAACAAAAAGGTGAGTAATTACTTCAATTTCATGCTCGAGAAATTCATTTCATTGTTGCACAGTAGGCAAAAAATGTTGTTAACATCTCAAAATTAGTGAGGTGATTTTGTACAAAAAGAAAGTAGACGTAAGACTATTAGGGAGTGCAACACTAATTGCGAGTGCAATACTAATTTTTCGGAGGGCGTTCAAGGAGCAATACTATTTGGGATTGCCAAAAGTCTAATGGAGAAGGAGGTCATATTAATAGAAGAAATACGGTTAATTATTCGCGAGGTGCATTTTCATTTTAAACTTTGTTTGAAAATCAATTATCTTTAAAAATCCTTTTCTTCAAATTTGTAATTATAAGAAACCAAAAAACCTTTATTTAATTTTCAACAAGTGTAGTTTATAATTAAAATATGAAAATTTACAATAAAAGTTCAGGACTGAATCCAAAAAAACTTTTTAAAAAACGAAACACCTTGTTTGAACCTGATAAGCCTGGAAATAACCTGGAAAAATAACATCGATTCAAATTTTGCAAATTTTAAGCGTTTTCTAACTTCGAAAAAGTTGACCTGGCAAAAAATAGGATTTTTCAATGTATTTTATAAAAAGGCGAAAAAAAGCAAATTTTTTGAGAAAAAAATTGCTTAAATTTTCGACAAATCATTTTCAAAACTATTCTCGATTAAAATCCGTTTATAGCCATTTCTCCTTCAATTCTTCCAGGTTCGAATACTTGCTCAGAAACTAAATTTGCTCTTTTTCGTATCCACTACTATACGACTAGTAGAAGTTCTTCATTCAGTGGGTGGCCGGACTACTTTGAATCAAATCACAATTGTAGAAGGAGGTCGTGCATTTGCACGGGTGTTCTGGTCACTCCAGAAATTGAAGAAATTGAGCACCTCAAGTTTTGGATTATTCCAGGCAACTCGGTCGTTTTTGAAAACCTATTCTATGAAAAACTGCAAACTATGTGGTTGCATCTGTCTGGCTGGAATTTTTGTTTCAAATTTTGACCCAGGACATTTGAGAATCAACCAGTTTTCTTACCAAGTATGCTAAAATCCGAGTCAAAAAGTGACTTACACGGGAAAGTTTCAATTCATTGTCCGTGAGGACGTTCGCCTGTCCAGCTCATTCCTTTCTTTTGTCTCCGCCAGAACCGTCTGGGGAGCTCTGGCGAATGAGTTGAGAGCAAGCACATTGCATGAGCTAGATACCTCCAAAAGATATGTGCAGGCGGGAGATAAATTGGACGATGAAAAATCGCCATAAGCATAATTTTGGTGCGGCGAGACCCGAATAATGAGACATTTACGACTTTTTGGAACATCTTCTACGGACAGAATGGCATTTTTGGTAATTTGAGTTGTAGTTTGAGGGGCTTCATTTTTTTCGATTTTTAAATTCGTATAGACGCTTATACGCAAAAACAGAGAACTGCTATAGGCGCACGTGTAGTCAAAATGTCTTTTTGATCTTCAAAAAATGCGGGAGTTAAGACGCAGACATATCATCTGATTCGCATGGCTAAGAGCGGGCTGACGTCACAATTTTCTGGAAAAATGTTCCCGCTTGTAGATCAGGCTATGATGTGTGTGAGTTTTCAATGAGACAGCCTGGCACGACGGTAGTCACATGCTGGCAGTTTTTTTCCTGAAAAAAGGTACCTGGATTTTCGTTTTTTCTTAAGTAGTCAAATTATCGAAAGCTACTAAGCTACGTGAGGAACTTAGGAAAAGTAGGATTTTAAATTGTTTTCGGCCTCGCAACGAAAGACTCACTACTATCACCTCCAAAAAACGAAAATATTTGTCGTGCCGAGCCCCAAGGCTCCGTTGAAGCGAAATTCCTAAACTCCCTAACCGCCGAAATTAATTTCTGAGTTGATTTTCCCATCACCTTCTATATACAGTCGTTTCGCCCCGAAAACGATTTGAATTCGGCTTCTCCTCAAATCCTCATTGCATCCTCTTTCTTATTCGATTTATTTCTAGCGGACTCTCCCCTTCCCATCCGTGGCGTTATTGTTCGGTTACGATACGCTTCTTGTGAAGGTTATATGCAAACGACTACTTGCCATTCGATTCTTTCTCCACAAACGAGGTTATTCCATTTACTTCAACTAAGGAGCTGTTTTTTTCTTGTTTTTTGTACCTACATTCAAGGTCCAAGTAGTGCGGAAAGTCAAAAATCACCTCGCAATTTAATTTTTAATAACGCCCGAATTAGTGCACGATAAGTGAATAAGAACAAAATTCTAGTCCCAGAGTCGTGACGATTTAGACAGCATATAAAAAAAACGATTTTATTCCAAAGTTTGAACTGCCACTACATTTCATGTATTGAGGTTTTGAATTTCCATCATTTAGTTTTAACCACACTTTTCTTCCGATTTCCACCGCAAGCGAAAGTTGTCTTGTTTCCGAATATCTGACCGCCATAACTTGGCTAGGTTTTTTTACGACCGTGCTGCCGAATTTTGAATAGTTTATCAGCATAGACACTCTCTCTGTCCCCTTTCCAACCTCGCAAACCCTTATGTCTGTAGTTGGCATCTGTTGCAGCTTGTTTTTGGGGCAATTTTTTGCCAGCTTGTTCTACATATTAACATTGCCTGACCCACATATCTTGAGCAAAATTCCAAAAAGTACGTTTGTGGCCTAGAGTGATTTAATTTGTGGTTTTTTTTTGATAGTTTTGAGCTAAAACTTGCATGGCTTTTTCACTGTTATAAATCATTTACAAATTCATTTTTTGCTCTTTTTAGAAAAAAAATTGTTAAAATTGTGGAAAAATTTCAAAAAGGTGTTAATCATTATCCACTTCCAAAACGTCATAACTTTGGTGAAACTGTACCGGGCAGCAGCTAAATTTTTCGGAGTGATCGACATTATTTCTCTTTTATCGAAAAATTACTATGCCAAGACCGGGGACCCATTTTTTCACTTCCCTCGCGGTATAAGCCGAAGCCTTAGTCTAAGTCTAAGCCTATGACTGATCAGCATAAGCCTCAGCCTAAGCCTAAGCGTAAGCTCAGCCTAAGGCGAAGCCTAAGAATAACGGGAAACTTTTTTTGTTGCTTTTTTTTGTTTTTTTTCAAATGCCGAAAAATAATTGCGGGATATGAATTATGACTTTGTTTAGCCGTTCCCAGAGATGCTGGTTTTCAGGCTACCATGAACCTTAACGATGTTCTTCTGCCCGCCCTTTGCACACTCTGAAGTTTCCCGCCATGTCAACCTTTTCGATCGTTCGGCACGATAACGTTCTGAGTCCCGCGGTGCCCGTTAATTTCCATCGAATCGTTAGGTTTTCTCCTTCGATTCCTAGCGATCAAGCCATAATTTATCCGTACAAAATCGGATTTTCTCCCTTTTGAGATAATGATGATGATGGCCTCCCTAGACACCTAACAGTGGAGTGATGAATGTCTTCCTTAACACGTGTCCGTTTATCATTTATCACTCTGTGCTGAAAACCGGTCTCTCTCTTCCCCTGACCTTTTCGGTTTTTTGAAACAGTGAAACAGAAACGGAAAACAGGCGGTGTCAGATGTTTGACACGTTGATGTCGTAATCCATTTCGTATTAATGGTCTGCTACTATGTACGCCATTTGCTATATATGGCCATATTTTCAATAGCTTTGAGCACAAGCTTTCAGAATTGGCAATCCATTTTTAAAATTTTAAAATCGTTTGAAAACCAATATATGGGTGGAGCCTATTTCTTAACTGTCCGTAGCTACCGAAAAAGTCGGAAAGCGCCGATTATCTAATATTTACGACTTCGGCAAAACTGAAATTCTTCAGATTTTTAAGATCTTGAGAGAAAGAATTATATTTCTTTCAAAAAACATGTATTATTTAAAATTCGTTTGTTTTATTATATTTGAGCTCATTAACTCTGTATCAAATTGACAAACAGATTATTTCATTCGCAAAAATGCCTAATATCGTAAATTTGAATGTAAAGGCAATTCCCGAATTGCTGCACATCTTGGTTTTTTGAGCTTATTAATTGAATTTTTAAGAACTTTTATTTTGGTAATCTAAATTTTAAAGTTCTTACTGAATTCCGAAAAAAATTTCTTCAGAATAGGGCTTCCATGGCGTCAAAAAGCTTGCCAAACCTTAAGACGACCTCCGCTCCTCTGCCTACCTTAATCTATGTGCTGAAACATATGCTTTTTTTGCAATTCTTGATTGTTTCCTCTAATTGATAGAAATGAGAAAATTTCATAAAATAGAAAATTTACGCACAAGTACAAGGATTTAGGCAGGCCAGGCCGTGAAACCCCGCCTGCTTACCATGGAAGCCCTACTGCAGAAAATGAGAATTCTGACTGTTCAAAAAAAAAAAGAAACCAGCCGTGTTTTTCCTTGAAATTCGAAAAGTTCCCCGATATTCCCCTCATTTCCGGAGCGTTGTGTTCCCATGGTGGAACGGTAGTTTCAACACACCGTCAAAAGCGATTATCGTGTCTATTTGTCTGTCGTCGACGCGACCCATCACACCAAATCGGTTGAATTGGCATGTCGCTACCCCTTTTTTAAATCGGCAATATATTTACTTTTTATTTGACTAAGAAGTAAACACTAATAGTTTTGACTGCAAGAATATACATAACACCTTATTTCACTTGGTAAAGTAATTGAACCGTTGTAATTGAGCTGAACATGATTTACCTACGAAAAAATGCCTGTGACCTAGGGCTTGCATGTATGGTTAAAAGGGCTGCCTGCCCGACCAGGCAGCATGCGCTTGCCTGTGCCGGTTTATGCTAAAAACAAGGTTTATGCTACGGTTGAAATTATTTTTTCATTTTTAATTTGATTTTCAACTTTTGTAATCTGAAAATTCACAAAGGTAGAAAAGAGGGGGAGGCAGGCAAGTTGGCACGGCGTCAGGCCCTGAATCGGCGCCACTGCCTATCATGAAAACCCTAGTCTGAAATCGATTTGGCCCAAAGACCAATTTTCGAGAATCATTCTCCTTCCGTCCTTTTTACGCACTTTTTTAATGAATTTGAAGTGAACGTGTAGTCGAGGGAAATTTAGTGAAACTACTACAAGTCCACGGTTTTCAGCAGCAACTTTTTTAATTTCGTAGAAATAGGTGCTTTTGTGTTAAAATTAATAATAGCTGAACTATTGGATAATGTACTTTAAGACGGGCAATGTCACTCCATATTTTATAAAATGTTGAAAATTTTGGTCAGAAGGGATCGACGGAAGATTTTTAGAAATCGAAAATTTTCAATTTCCGATTCCCATCAAACATTTTATAGCTCAACAGTTTATTTCGAAAGATACAAAAAATCAGAGTCATCTGTTCGCACACCGTTTTACCCCTATCAACAGATGTGTTGCCCTGCACATCTGTTAGAACTTCTCACTATTCTCTACAACAGATTTTCGGAACAGAAGGTGTGATGTTTCTACCTGACTATGAGATTCACGTGCAATTCAAAATGATTTTTTGAAATTTGGAGATTTTTGAGTTATCCATAATTCCGTCAAAGAGAGATCACAATTTTTTTCGTAGATTGACAAGAAAATTACCCCAACAATACTCAAAACAATTGTAAGTACAATTGCATTATTGCTCTTCAATTCTTAATTTGTGCTGAAACTTTCTTTTGACGTTAACCCCTGCAAAAATGCAACTAAAATTGATCAACACTCGTCTAGTAAATCTACTAACTCGCCAAGGGAGAAGTCTTTGAGGGGGTCCGTACATTTGGGGTTTTCATGCTAAAATTCCTACAGAAGAGTGTTAGTTATGATCTCTCATTTTTGCGCATTTTTAAAGTGACTTTATATTCGGGAACCTTCAGACAATCATTGTCCGCACTTTATGGAAATTTTTTTTCGTTTTCGCTCAAAATCACTAATTGATCAACTCCAAGCATAAAAAATCAAACCCCGGTTTTTTAACAAACATTTTGTTAGTTGATCATTTTTCAAAATAATTTAGTACTCTCAACGAAGTTATGCAACTCCAAACTTGGTTGAATCAGTATTTTGCACAAAGTTCGAAGTGAGATGTAGTTCATTCCGACGGTTTACTTGCGAATGGCGAGTTAAAACTTGTGTAATGTACCATACATTTCTGAACATTAAAGAAAGTTCATACATTTTTACAAAAATAAAAATTTTCCTATTTTTGCTAGGAGTTGATCAACAAATTTTGAGAAAAAAATGAAAAAAATAATTTCGAAAAAGTGCGGACATTCTAGGTTCCCGATTAAGAATAAAATCACTTTAAAAATGCTCAAAAATGTTTGAATGAGTTGTGTAAAACTTTACTTACAAAAATAAAAATAGAAGGAATCGAACCAAACCTTAAATATTATCAGACGCGCGCACTCCCAACTCGGCCACCGCGGACAATTTTCAACTGCGTCGATGTGGTGTCACCCGACATTTTTACTTCGGTGGTCACGCAAGCTGAGATTTGCGTGGACTGATAGTAAGACAGTCGATTTCAATGGGGTTCTATCAACCTAACTTGCTGAAACACATTGACCGGGGCAGCTAAATTTTTTGGAGAGATCACAACTCACTCTTCTGTAGGAATTTTAGCATGAGAACCCCAATTTCACGGACCCCCTCAAAGACTTCCCTTGTAAGTCAAACAAAAATTCTGAGATTTTTCAGAGTACTATACGTAGTATATATTTCTGAACAATTCCCTCAACAAAATCCTTTCCACTTCCTCATTTTCCCACGTAAAGTCAGAATACATTTTACTTATTACCATTAATACCTAAATGAAATACAGGTCGATCTTGCAATTCTACCGTCTCACGGCTTTTGTACTTGTTCACCGCCACTTCCCCCATTCTTTAATCCAACCACACACTTTTGGCACACAAAGTGTTCAATCGAAATGGGACACTATTTGCTATTGCTATAATCGACAGGCTGGTGGCAGGAGGAAAGCAGCAAACGACGAAAGGCATAAAACAACTGGGCGTTGTGTTAATCACCCGTATTAAGCATTCTATATTAAGCGGTCGACAAACAGTTCATTCATGTTGACTCGATTTTCGATCATTTCACAGAGTTTTGCTTCGAATTGAAGGTTCATGGAGAGATAGCCACTCTGTCTATTTTCAGATTCCGCTGAATTTTAAGATGTTTAATACTTATTTGCCACCTTTTCGACGGAATGACATGTACCGGTCGGCTAAATCATGGACAGAATCGATCTGCTAAGAGATGACAATTTTTAATGTATATACTCAGGGCTCAAATGATCGAATTGCGTAACGAATTTTTTAAAAACTTTTATCAAAATTTTCTATTGGTTCAATGTTTCGAAAAATAGACCGGAACATGTAATTCCGTACAAAAAAACGCGCTTCTATCGTGTCTGAAACAACAATCTTTTTCATAATAACTTTCAACTACAAACTTGTTCTTTACAAAAAGATCAACAATTCGATTATTAGGTGAGCACGCTGGTTTTCTGTACAAAAAATTTTCCGCGCAGATGTGATCTACCAAAGTAATTTGGAAAACCCGTCAATGCTTCGTTGCGTTTCAGTGCTATTTTAGGATCTTTGAGAGCTCACCTGCCGTGAGCTTGGCTCTGGAGATTCGCAGCTAAAAAGGAGTGACCGTTTCTTGAGGAGCCGTTTCAAGGGGCTATCGAATGGCATAGGTCTCATATGCAAGCCGATGGGCACCTTCTGACGGTTCCCTAGTCAGATAGAAGCCAAAATTTGGGCGAGGTATGCCCATTGTCATTCTAACGAAATGGCCTCCGACGTGATAACTTTTCTCTGTCAATTACTCTGGGCACACTCCCAATAAATCCTACACACCGGGGGATTTGAATTGAGTCATTCAAGTGTCAGTGGTTCAGTTTCTAGCAGTTGATACGTGTTGGGTTGTGTGGTGGTGGTCAACCTGTCGCCCGATCACTCACACACACACATACTTTTCCTGCCATATTCCTCCCCACGAAGAGAGAGAAAAAGAAGTTGCATCTTTTCTTTTCTATAAAAGTCTCTATCCACCAACACACCCTTATTCGCATGTTCTCGCACTCCATTTTCCAAACAACGCAATCAGTGCATCCAAATCTACATAATCGATTCAGGGGGAATAAACTGTGATAGTTTTCTAATACTTTTCCTTAATTGAAATTTTATATTTTTGAAATAATCGACCGAATATGCCTAATTATAATTAAAATTTAGCGAATTAGATTTGAATTTAACAACTATTGCGATGTTTTGAATTTTTGACCGGAGTATTTTTTCAAGAAATTCTCTTTGCTAACCATAAGCTGAAAAATTTTGATTTTCTAGTTTTTGGTTTGCCCGGTCAAAAAAAATCTGTAAAAATTTTGGGGCTTTTTTCTCAAAAAAAAAAAAAGAGATTCAGGAGATTTGATTCATAACTTCAAAACTTAGATGCAAAATCTTTTACGTGGTGTCGATTTTTTGATATTCGAAAAATCCGGTTATTAAACAGCTCTATTAAGAAAAATTATTTCCTGGACCTATTTTCTGAAGAATTCCTCGTGCTTATCCCACTCTACAATTTTTCGATTTTTCATAAAATTGAAAGTTTCGCCGTTCAGTTTACCCTTCAAAATCAATTTTCGACGATCCCGAATGTTCAGAATGTTGACAAATAAATTTAAGATTTTGTCAAATTTTCCCACACGTACTTATCCACCAAAATTGACAAAAGACCCTTAAATTTAATTTCTAAAATTTTCAAAAAATCGTGATCCATTCCTCCATGTCATGTCTTGCAAGCGTTGCCTCAAAGTCATCAATTGAGCTAGTTGTCATCAATTCAGCGATATTTAGAGATTGAAAGAATGAGTAACTCATCCTTGTTTCTTCTTCATCTCCTCACTTCACTTCCAATTTTCTAGGTCATCTGTTACTCAATTTGGCCTGGCGATTAGTCATCTATTTGTTCGTCAGACTTTGGTGCAAATTGTCGTGTCACTGAGTAGTTATTTTTTCTTTTTGGTTGATAAGGTTACCTGTTAAGGTCATATCCTTTTTGGCCTATTTTTCCAGTAGTATGATTCCTCTAATGGTCGTTTAGAAGTTACTAAATGTTTCGAAGTTGTTAAAGTATTAGATTTTTTTAAAATCATTAGGAATGTTTTTTTAATTAAAAACAGTGTTTACAAAAAAAATTTTATGTTTTAAAAACTTAAAATAAAGTTTAACAAATGTCTAAATTGTTAATTTTTAAAACTATAAACAGCATTGGCATTCATAAAAAACAAATTTCGACAAAAAATTCGTAAAAATTGCTGAAATCGCAGTAAAAATACTCACAACGCTGAATTTCTCATAAAATCTGGAAAATCAAGTCGTTTTACTTGATATTCGATGCCATAGGAAATTAGACAAAAAAAAAGTGATTTTATTAAAGGCTGGTCAAAATGTCAGATTTCAACAACGTTTTATAAAACCGCTGTCAGAGTAGAAAAATATAGGTGTAAAATGTAGTTAAAAACTATTCTTCGATTTTCCTTATTTTTTTCTGCTAAGTGATTGAAATTTTCACGTGTAGAACAAGAAGATTTAAATTTAAACCAAGTTTTTAAATTTTCAATTAAACATACAAAAACTACTATTTTCGAAATTTTTAATACAACAGTTTAAATTCCAATTTTTCTTTAAAACATATTTTCCAATGCTGACTCTGAATGAAGTCTTAACACTTCAATTTCAACATTCTGTTGCGACAAGTCGTCCCATCCATTGACCGATAACAATGGATCAATCACTGACGAGGGCCCCCGGGCGCCGCCATCATTTTCTCTCTCTCTCTATCTATCTGTCTCTCTCTCTCTCTTTGTTTCTAAAAAGAAGGAAAATGAGCTGCAATTTATCAAATCCACGGTCTTTTTCCCTCAAATTCTCTGCCGTCTCTAGTCTTCTCTCATGGTCATTGTCGCCCTAGGACATTTGTGACTCACAAAATGTGCCGTATTATACAAAAATAATTAAAGTTCAATGCGTATGCGTGGGTGCATTTGTTGCATGGGTGAGGGCAAAAATTAGCCACCCACAACAAACTTAACGTTTTTTTTTTTGTATTTTGCCTTTTTCTTCTTGATGAATGGTGCACATTACACCTGTTCTTTGTTACGGAAAATTGGGCGCAGAGAACTAACTGAGGTGTGAATACTTTGTTGGTTTTTTTGGCTATACCTATTAGTAACCTTTTGAGTATTAAAAAGAAAATTTGAGGCATGTTATTTGTCGAGTTGTTGGTAGGATGTTGATAATTACTGTCATCGTGATATTCTATTAGAAATTAATATTTATTTACACGTTTTAGAAGAATTGGGGATTTTTATGCAAATGATCCAAAATAATCTTTCGACAAATCACGACGGCCCACACTGTTTTTGTCTTCAGCCAGCAATCAACGTATTCAAACTCCGCCTACTCTGTCTGATTGGTAGGAAAAGTGGGCGGAGCAAATTGCTGATACTTTTTCGAAGTTCTCGACCCTTAGCAATACCAGAGTTCATCAAAACTGAAATATTGCGTTTTTAAAGGATATATTATTAGTATTATTATTTACTCTCGATTTTTTTATACTATTCTGTGGTTGCTCTGAATTTCAGATTATTCGAGATAGTTTTCGATAAAGCGACAAGTGATTGTTCAGTTTCTGATTTCCATAATTTATCCTCTAAAAGGTCAAGGTTTCGTTTCTTTGCAAAAAACTCATTTTTTTGAGAGTTTTCGGAATTTTGGCTAGCCTCTCCAATAAATTAATTCAAAATTTCGGAAATTATTCTTCCATTATATCAATAGTGTTAATCTCACTATTCTAATTTGATACAAACAAATTGACTCTTCATCGATTTCCAGCCAAATACTTTACATGCTTGGCAACTGAAAATTAGTGTTGTTTTTCAAATTCTCAGTTTCCAGCCACTGAAAACATGAGCCTCCATTGGGTCCGTCCCTCTCCTTTAGCCCTTCCGAAACTCATTTCCCAGTACTCTCTCCAATCTGGTCAACATTTGAAAGGCTGTTGGGGCGAACGAAAGCCAATTAACAACCGAACAATAGTTTTTTCCAATGTCATCGAATCCTGGCTTCTCATAGCCAAAAATGCTGATGACTCGAAATTGCTTTTCGTTTGATATACACACACATCATCCTGTGCCACACACTCTTTTCCCCACTCTTTTTCACGAGCTTTTTCATTCGGAAGGCGACAGAGATCAATTACCGACATATGGAACCAATCGAAGTACTCTCTCCGCTGCGACTACCTAATTAACCCTTTATTGAAAAAATGAGAGAGAGACAGAGAGAGGATATGAACGGAAGAAGGAAAAAGAGGCAAAGCAATTGTTTATTGTTTTTCGAAACAATTCAAACTTTTGTTTGGGCTGTACGCCTTTAAAGATGGAAAAAAAACGGAAATTTTCCAGCAATCCGTAAATTTTTTTGTCGGCAAATTGTTGGCATTGGTAATCGGCTAATTATTCGCCGATTTGCCAGAAATTCATAATTTCGGCTACTTATGCAGGTTCGCCTATTTGCCAAAATTTTTCATTTTCGGCAATTTGCCCGTTTGCCGTTGCCGGAAGTGTTTAGAGGAGTTGTTTATGAGACGGAAGCACTGTGCCTGTTTGCCAATATTGAAATTCTGAAATTTCCAAAAAAATGTGCACAAGCACCGCCAAAAACTTTTTCAGTTGCCGGTTTGCCGGTTCGCCGGAAAATTTAAGATCCGGCAATTTGCTAATTTGCCGGAAAAAACCGGCTACCGCCCACCCCTCCACCGAATTCGGAAATTTTGTAAAAAACAAGTTTATTTTTGGGCCAATACGATACTACTTTTCCTAAAGAAGCTTACAGTAATCAATGTATTATCTTTTCCATCTCGAATGGTACCTGTGTTTAACGGTCACATAACTGTGACGAGTACTTGAGATGACAATACTCTTATCATAAAACCTCCCCGCTCGTTATACCCCTCTGCTTCTCGGGTGTAGGGTTACCGTGGTTGCTGACGGTTTCGTAGGGATTACTGATGTCAGAGAATTGGATGAGTAGTTGGGATTAGGAGATTAGGGAAATTGGAAGACATGTCTATGCACTCCATATGTTTCTAATAAGAATCCTTGGAAATCGAATTGCATATAACTCAAGAATGGATAGCTACTGGTCCTGTTTCGTTTTGTTATCTTGATTCTTCGAAATGGTGCTCACTCACTCGAAGCCCCAGGACGCTAGTTATTTTCGTAATCGTCGCGTTCGTTCTCGAGCTCCTCCTCGAGTTGGAAATGTTAAGTTGTGAGGGCTATCGCGTCCACAGATTTATAGAGTCCGTCGTGCGGTTTCGCTGGGTTCTCGCAGCAACCCCCTCCCCCCGGCACCCACGCAATATCGGTGCAATCGCGTAAACTTTTTGGAGCACGCAGCACACAATGTGCGCGGCTCAACTCTGTCTCACTCTTCGGACATCCAACATATGGCACTCCTCAAAGTGTTCACTGGCCTCCGCTCGGAAGTCAGGCGAATTTATTCATCTCTTTGGAGATTGGCTCACAATTTTTTTGATTTGAATTCAGTGACTATTTATCGATTTCTAGGGCTTCTATGTAGGTTGCCTGTGTGCCTGTCGTCTGACGTTAAGGCGTCCTCCGCCTGCCTCTTCGCCTCAATCCGTGCCTTGTGCCAAAACATACGAATTGTAAAATGATTCTCAAATTGATAAAAATGAGAAAATTAAGAATTTGTGAAATTCAGACAGGCGGCAGGCAGATCTCAGACAGGCATCAGGCTCAGAAAACGCGCAACTGTCTCCCATGGAAGCCCTACTGATATGTAAAGGAGATATTCGGTTCAGATAAAATAAATTGAAGTTACGCGAATTCTGAATTTTGAATATTTTCCAATAGTTTCTAATAGTATGGGTTAGATGTTGCATTCTAGATACTTACAAAATTTTTAGAAAATTCCGTGGTAAAGTTCAAAGGACACTCTTTGGCTCTGAATATTGGTTAATAATATGAATCCGTTCTGCTTTGTTTTCCGTACTCCAATTCTTGACGTTGATATGAAGCCAGCTCGAATAATAGCCTCGCACGTAGTCAGGCTGTCCCAATACGGTTTGATCGACAAAAAATGCTGGAGTTGCCCTTCAAAATGTGACGTAAGCGCGCTCTTAACCATGCACTATAAAATCAGTTGAGAACTCTGTCAAATCAGCTCCCGCATTTTTTGGAGATCTACGTAGATCAAGCCGAACGGATACTGGTACTCTGTCACCACGAGCTCCTAAGCACTATTGTGCAAGGACACGTCTTATTTTCTGAACCGTCAAAAATTGGCACCGTTTGAGAATGAAAAGATCTAAAATTTTCTGAGTCTGTATTTTTTTCTGTATATAAGTCCTACCGAAAGGGTCCCCCGCGCTAATAATTACCCGCTTCAAAACAATGTGTACTACTAGCCGAGATAAGAGTTTTGTTGTCATGATACAACAAGATTTCGATCACCGCCCATTTTTCTTGTCAAAAAGTTCCGCTTATAATCTCGTTTTCTGATAATCAGAGATACTCTATGGGAATTGGTTGAGATCCACGCCATTAGTGAATGTTCCCCCAATAACCATGGAGCGTTAGAACAAAGACGAAAACCCGCCAGAAGACACACATTCTCGAGAGCAGGAGAAAAACGAAGAAGTGGGAGGGGAGCCCGCGGGGGCCGAGACTTCCCACTTGCCGATTTGTGCAACGCAATATCGATGAGGAGTGCTCCGTCCATTCGATACAGTCTTGCACCATGTTTGTTGAGAAATGCTATTTGGGTGGCTGGCAGAAGTTATTGGTCCAATTTTCTTGTCAATTTGATCTGACAGATTATAGGTTCTTGGAATTCGACTCTTCACCGAAAAAATCGATAATTTTTCGGAGTTTGTTCAATTTTTCAGTTGAACATTTAAAAGTTTTACTAAATTCGATTCTAAATTTTAAAGCACATTTTGACCTAGTAGGACTTTCGGAATTTTGTAGCCTGTATAAAAAATCGGTGGCCAATTCTATAATTTTTTTTCGTTTTGAAATTGCCTTTTTATGAAGTTTACAATGTGGAACATTCGACTTTGAATGACTTAGTTTTTCAAATTCCACCTAGGGTCAGAGTGTCCCATCCCAGTTTAATCGACGTTGATCTACAAAAATCGCGGGAACTGGTCTGACGCAGAGCTCGCCACTGATTTTGGCAGGGTTAAGACTTGCTGACAGCACATTTTTTCCTGGAAAATTTTCCGCATTTTTTTGTAGATCAAACAAATTTGATATTGCCTCGAGTTGTTCGCTATAGTTGGCTAGTTTTGAAATCGTTCCGGAATTTCTTGAACTTCGAGTTCTTGAAACATTTATGTTTTCACCAGTTTTCTCTGCGTGTTTTTTGACTGTTCGAAAAAACGGTTCTTAGAGACTGCTTTGCAAATTTCGAATTCATCCAAAAAAAAGTGAACAAATTCTTCGTATTTTGCTTCTAGAATTTTTGGAAATCTCATTTAAAATGAGTTTTTGTGAAACATTTTAATCTTTAAATAGTCAGAGTTACGTCAACCAATTCTATTTTTTGAGGAAGTTATTTTGAGAAGAAATACAACAAATCCGCAATTTTTTCCTTCCGAATAATTAACACAATCCAAGATCCCCCCTCAAACCGGATGGCATTTATTCGGATCCCGGCAGGTGTTCGAATGAGATTTGTATCCATTAACACATTGTGCATCACATAGACACATTGTCAACGTATGCACACAACAAAATAACTGCGCTCGTTCGCACCTCAATCCTTTGATGTTCTCCGCCGGGGGCTCCTGTAAGGTCAGGAGTTTTCTAAAAATGTTGCCTTCTTCTCCGTCTTCTTCCTCTTCATCATCGAATATTCCAGAGGGGGGCCGACACGCTTCACTTGATTTTCGATGGCAATTTGTTTGAAGAATTCATGAATTCGAAGAATTTATTTGGGAATACTCTATTTTGCTTTACGTTTACATCCAACTTTTGGCAACTTAAGCGCCTCCAACTGCAACCATATGGTGCTCAATGAGCCGAGAGGGATCATCTGTGAATTTGGTGTTTTTTATTGGTTCCCTATTTGATTGGAGAGTTCATTTTGCATACAATTACCTCTATTTGGCTCAGGGGTGGACGGGCACAATCCGTTCGGCATTTATATTTTTGCCGACAACTAGGGCAAATCGGCAATTCGCCGATTTGCCGGATTGCCGGAAGTCTTGATTTTCGGCCAACCGGCAAACATCAGCGTCCTATTTTACTATTCAAGATAAATGTAGGAACATTCATAGGATGCGGATACAATATTGCCGATAAAATTTAAATTCTGATCAAAAAAAATGAACCACAATTTGCCGCAAGTTCTAGCCGTTGCATTTCAATTCCGGCAATTTTATGTCCGTAAAAAATTGCCGCCCACCCCTGATTTCTATCAGTCTGTCACCGATTCTAGTGAGCCGGGGGGTCTTCCATGCAGGATGAATCGGTGTCTGCTACATTAATTGCGCAATCCACATTGATACAGAGCAACCTGCTTGCAATTGTTTTTCTGTGGCCCGTTCTGGTTACACCTATAAAAATGTGGTCGAAGAATCGTATAATTTGGGTCATGAGATGGTCCCTGGGTAATTGGAGAAGTGCCGTTGAGAGAGAGAGAGCCAATTACGTATGAGGTCTGGTTCCTCTGCACTCGGGAAGACGCTATAACCCTTCGTGGAACTTTTGGCGGGAGATATCAAGAGATATTTTCCACTTCGGTAATTATCGCACTTATGGTACTCTCTTTGTGAATGATTTACCTATAATTTATTGAGCAGTTGTGATTATCCTATTTTGAGAACCTAGAAATGTCATAGGAAACGTTTAATCGGTGAGTATTGTTTTACGTTAAGTTGCTCCGTTTTTTATTTGACTAGCTCGACACAGCACCTTTGAATTTTACATTGGTTTTGGCCAAAGGTTTTCTGTTTACTTTTATTTTGCAGTCTTATTGATCTGGCCTGCTTTACCGAGCTAAGCCTAATCCTGTCCCGGTTACAGTCCATAAGACAACATCAGCTTTTGAACTCAATAATTGCCGAATTGCCAAAATGCCAAAAAATTACGATTGCTGCCCGTCTGAGTAAGTCTGAAACAGTTGTGATTGAGCCGAAACCTACTCGGAGTGGGCCACTTCCCTATTTAATTTCTCGGTTGATTTTCACACTTCCCGCCGAGAGCCCGCAAGCATCTGCGAGCTGAACGGTTTCGTCGTCGTTTTTCATGTCTATTGCTAAATAGGTACGTGCGCGTTACACACTCATAAACATCAATTCTTTCATAAAGTGGTGGATAAGTCGAGTGGATTGCATCTGACACCACACTTCCGATAATCGCTTCGTCTTCTTGTCATCATCGTCGTTTTCTTCTTGTTGTCGTCCGGTCCCCACACACACAAACGGCTACTTCCGACGCGTCGGTGTTGTGTGTATGTGTCAAACGGCACCACCACAAGTGATTGCCCTCGGCCGTGTGCTAACTCGCATTTTGTCTTGTAATCACGCAATAGTGATAACAATCGTTTCCGGACCATTGCTAATATAATATATTGGGGCTACTGCGGGCACGTCTTGGCAATAACCTGGATGCAAGTTTTATCGTTAAAATGTGAAGCCCATGTATGATTGCGAAAATCCTAGTTGAAGTTTTCCCATTCAAATAATGGCATATTTGAAACATTTCGAACTTGAAGATTTATATCTGTCGTAAGTGGAACGGTTCATTTGGTTTCTTGCGTCTCGTCGCGAAAAGCTTTCACTATGGTATGAAGCACGAATGGGGAAAATCGAAGTCGAAGGTCGGCTCGATTTCGGCAATTATCGAGTTCAAGGTTTCGGAAAAACTCAAAAATAATTTTCAAATCTATTTATTAGTTCTGACACGCGGACTCGGCAAGTCCCATTTCGCTTTGATCTACGAAAAATGCGGGAGTTGAGAGACTACCGCAAACATCTCAACTGATTTCGCATGGTTAAGAGTGTGCTGACGTCACTTCCGGAAAAAAATACCCGCATTTGTAGATCAAATCGTAATGGGATAGCGACGTAGAACAGACTCGCCAAATCGATATATGCATAATGAAAACTCTAGAACACTGCCACCCTCATAAAGTGAGTGACAAACATTTCTGCTTTGAGGAACTATAGAACCCCCTTTCAAGTCGATCTTCACGAGCGCAAATTCTAGAAAGATCTGACAGTGGCCGATTTTTTAATGTTTCTAGGCCCACGTAAAAAAGCTATCTGATGCCTTGTTACATTCCAATTCGAAAATATCCCTTTTTTTAATTTTTCGGCAGCAGCCCGGTCCGTGCCAACAACTTACTAAACCCTTCAATACCCTGCCCTCCAAACTTCTGGCCTCCCGGCTCCGTGTTGTTCAGGGTGTTGTACCCCCCCTAGACACCCAACTGACCATTCACTCGTCCTCCCCCTCTACAAGAACCACCACCACCTGATCCATTCCGCAATTATATTCCGGATACTTGTCATACAGAGAATACCCGGTTTGCTGCTGCCAAACGGTTTTCATTTACCATTTCTCACTCCTTGATTGTTGTCTATTCTTCGATTCGATGCGGCAAAACTAGCGCCTGGTTTGGGATTGCTTTAATAGTAAAATTTTTTCTTATTTAAATTTCCTATATTTTTTGTATAAGATTTTCTTTTTTAATTGCCAATCCATGGGAACGTCTCAAATTGCATAAAATTCCAATTTGAATTCCCTCCAAGATTTCACGATGGAGCGCACTTGAATTATTATAATTTTTATCAATGAATTTTTAGAGTTATCATCTCTGACTGATTTTTTTCTTTGTTAGTAGTTTTAGAGGAAAAAATCCAAGTTAAATGGACATTTCCTATTAGTTTTACAATTTTTGGACTACTTTCCCCGCCGCCACCGCTAAAAATCCCAATGCAAGTTTTCACCTGCTCTTGCACGACTCATTTCCGCGAGCGCGCGCGCTCGTACTTTTTATCTTTACTATTTATATATCTCAAAAAAAAATCCCGTTAATTTTTTTTCCCTTACAATCTCATATTTTACTCATTTAGTTTGGCTTATAAAATGCTAAGATTAAAATTTTTATATTTCATTTCCAGATCACATACACAACGAAACTGAGGGGAAAAAGTTATTCCTGATTGATTTTTATGATTAGTAAATAACATAGTTCGGCCGCAGCTAACGGTGACGAACGCCCGCAATTATGAGTTTTTCGCTTAAACATCAGATCTTTTTCGAATTTACTGTGAAAAAGCGGGCGTTTTGAATTTTCCGACTTAAAACTGCTTTTTTTTGCAAATCCCGACTTATTCAGAGAAAAATAATTCAAACTCCATTTTTCAGCTGTAAATGTGCTCCGGATCATTCCGGTGGAGCCGACGTCTAAACTCCTATTATGCGACTATTCTTTGAAATACACGACAATTACAACTATTGCGTCGTCGAATTATGATCAGGTTGCTAATATTCGGTGAGGTTTTTTGATTTTTGAATGCAAAATTTGAGTTTTAAAAATGGAAAAAATGCGATTTTTAAATCAAGATATCGGAAAAAAAAAATTTCCAAGAAAATGGTGGTTTTTATCGGGGTAAAAAAATATTAGAATAGAAAATTTGGATTTTCGAGTTCGAAATGAAAAAAAAAAAGTTTTGTTTTACACTAAAATCCCCATTAAAATTGGAATTTTTTTAAGAGAAACATAATTTTTCAATTTCTAACTGTAAAAAGCACACAAAATTTCTTGAAAATTGGCATTTAGTATTTTTTACACGAAAAATGCATTAAAATTGAATTTTTAAAACAATTTAAACTTAAAAGCTTAAAAATTTATTCTACACCGGTAAATGACGAATATTCAAATAATTAAAACTTCGAAATTGTAAGTTAGAAAAAATCAAATTTCCTCCTTATTCTCAATTTTTTTTTGACAGCAAAATTTCAGTTGAATTTTCCCATAATTTTGAATTAAAAATGTGTTTTATTCCAAAAGAAAACTATTTTACAAAAAACTAGATTTTTTCCCAATTTTCTATGAAAAATTTAATTTAGGCCAATAACTTATTTTCTTTTTCCAGATCACTAATCATATCTTGTGGTAATAATAATTTCCAATTTCCGGATGCCTACTTCAAGTCCTTAACCGCGTTGCATCATCTGCGGATAGTGATGAGTTATGATATTATCAGCTGGGGGTGTACAGAACATCTGCGATTTTTGCGTGGAAATTTAGAGGTCAATTTTCGGAAAAATTGGAAAAAGTGGGGCCTAAATCTCAATTTGAAGTAGATACGTGTTCAAAACTTTCAAAAAATTCAATCAAAAATTCGATTGGAATACTTCAAAAAAATTTGATTTTCTTCGCGAAAGCCGGTAAATTACAAAAAAAATTCGTTGGCGATTTTTTGGTTTCCTCTAGTCAGAAAAACAAACGAAAATTTTAATTTTTAATTATCGTTTTAATTTTTCCAAAAAAAATTTTTAAAAATACATATGTTCATTTAAATTTTAAAAATATCGGAAAATATTCAAAAAATGAACTTTTCTATCGCAAATTTAACAAGAAAAACTGACGAAAAGTTCTTTCAAAAAATTAAAATTCTTCTATATCTTAGAAAGGCTAACAGTTTTCCCATTTTTTGACTCTTTGAGCAAATGTATCACGGTCTCATTACCATAACCATCCAAAAAGAAAGATGTGTCGTCTTCTATTCATCCTCCTCTCGACACCAAATTCTTAAGATGAGCCCCAAGCCACTCGATGTCTCTAATTAGGCAAGTGCCCCGTGCGTCATTTTGCCATTTGTACGGCGACATATGACCTCCGGTGTGCTTGGAGGACTGCGAGAGAGGAGGATTAAGGGGATTTTTATGTTCTACAATTGATTTTTCTTTAGGTCAAAAGTAGGGATTTTAACGCCAAAAATAGAGATTTTTTAGGTCAAAAGTAGGGATTTTAAAGCAAAAAAAAAAATTTTTCGGCCAAAACAGTGGTTTTTAAGGAAAATTTAATTTTTCCGTTTATGACACCTAAAATTGGGGTGAAATTTTTTTGGATAATCTAAAATTGCAATTGTTAATTATTCCAAGATTTTTTTTTGCATTAAACGTTATTGTAAATACATTGAAAATCACTTGATCCGAAAATTTCATTTTTTTCAGAGAAATATGGTGTTTTAATAAAAGATGTGTTAAAAAACCTAGTGCATAGATATATAGATAATTTTGTACTTGAAATTTGCAATTTTTAACTTCCGACCCGAGTAAACAGAATTTAAATCCAATTTTAGGTGAACGGAAAAATCCCAATTTGCGTCTTGGCCTTAAAAAATCCAAATTTTTCGGCCTAAAACTCCTTTTGGCCTAAATCACCCTATTTTTACCCTAAAAAAGTCCCTTGTTTTTCCATCCCCAGGAACACGTAGATGAACACGTGTTAGGCGTGAAGAGGTTAAGACCATTAGCCATGTACAATACTGGAGTATAGAAGGGCTAGAAGTAGCAGCAGCATGGGGTGCTCCAAGAGCACAACCTCAACAGATGTATAAAGTGGTTTTTGAGTAGATTTGTGGTTTGCACTCGGTGGAAAATCTGAAATTTGAATTTTTTAAAGCCTCGTATTTTTGTGCTGAAAAATGTACATATGAAAACCGAAATTTCACCACCCTTTAAGTACGGGAAATCTCCGGGGAAAAGTGGAGCTCAAAAATTGCATAAAAATGGAGATTTTAAAGCTAAAAATAGCTATTTTAACAAGATTTTTTGCAGGGGAGACCACATTTCTCTGTGAAATTGTTCGAAAATGTGGCCGCTGCGAATGATTTGAACTCGATCAGGTTTTTCTTGGAAAATCTAGAAAATTTTGCTGAAATTGGCTCAGAAATGTCCTAAATAGTAGAATTTTTCATTACATTATAACCCTCTCAAAATAATATTAAGTAAAAACAATCAACATTTTTTCACAGATCTACACCGCCTCAACCTCTTTCGAAATGACCGAAGACGTCCTAATGCCGTTGGCTCGTCTCCTCTCGTAAAGATCTCCCCCACGAGATCACGGAATATCGAGCTTCCACAGCGACTTATGATTTGTGCTCGCCGCATTTACAGGTATATTTTTGGGTAATTGATAATTCGCCAAAAAGAACAGCAGCCGAAAACTCAAATTTTTCACGATATTTGCCGAAAAACTAGATTTGTAAAGTAAAAAGAATGCAAGAATTTTTAGCTTAAAAATCTCAATTTTGAACGATTTTTAAAGCAATTTCAGTATGAAAAATCTATTTTTTGGGTAAAAATTTGGTGAAAACGCGTTAAAACCTGCATTTTTAAATTCGCCAAAAATCAAGACTTTGTTTGTAGTGAATTTTACTGTAAAGAATATTGTGTACCTATTTTCTATTTTTATGCGTACTGCGCAATATATTTGAGCGCAAAATACCTCCCTTAGCGAAAACTACTCTTCAATGACTACTGTAGCGCTTGTGTCGATTTACGGGATCGATTTATAGAATATCACAATTAGAAATAAATGTGACTGCGAAAACAAAAATTTACTTCAAATATTGAGTCCGTAAACCGACACTACAGTAGCAATCTAAAGATTTACTGTAGTGTTCGCTACGAGAGGACTATTTTGCGCCTCAAATTAATGTGTTGCGCAGGATGCATTCCCATCTTGTTCTCTACATTACCACCACGTCTCACAGAGAGGGAATTAGTTGTTTATTAGTACGTGGGGGGGGGGGGGCTTTAAAGCTTTCTACTTCTTCTTTCTTTCCGCTTTCTGACGTACAACCATCTGGTATTCCTGGCGGTGGGGCAATTGAAAATGAGAACAAAACATCGATGGAGGGAGAAGAGAGCTTAGAAATTGTGATCTAAGAATCCGCGCGGAAGGAGGACGTCAAATATCACAAGCGACGGAAGTTCAGCCAGAAGCAATAAAGGCCTAATTAATGATGATGAACAACCTCCCTGAAAGAGAATAGCGAAAATGTGAAGTTTTTATCCCATCTCAAGGAGCGATTTTTTAGTGATCATGGAGGAAGTGTGCACATAGTCTACGTGCCAGAGGCCCTATGCCTGCCTTATGCCTACTCACATGCTCACCCAGCCAAACTCTCATCAGAGTTCTACATTGTAGAATTTACAACACTGGAGTTTTATCCTGCCGTAACGTGGAAAATAGGCACCCTACGAATACGTGCCTGATCAACATGGATGCCATATAGTCCAGGCTGTATATTCGTAAAACAGGGGGCTATTTTTTAGGCTCATGGGTTTTTGTCGGAGAAAATCGAACATTGAGAAAACCAGAAATTTTTCAAATTTTCGTATATCCACGAATGCTATCGTTTCACCCGATTATCGAATCTCCACGTCGCTCTGTAATTTTAAGTTTAGTTAGTCCATTCGCCCAAGAAACTCCAAAGTTACAAATGCTTAGTTGTAAGCATTTTCAAGAAACCAAGAATTGCAGTTCCTGGCATGTTTTGGCGCATTCAATAATGCCGCTAATAATAATAATAGCATTATGCCTCCTATTATGATGTCGCGTTGTCATCGTTTGCTTCATGCTGCTCCGACATATAGCAGCTTTATGGGGGTTTTCTCCCTCCGCATCAAACGAAGTTCCTCTCTTCAAAATGATGATGGATATACATATATCTATGTTTATAGAAGGATTGAACCCCACACTTTACATATGAATAGATGGGGACCTTGTTACCTTGACTACATTCGGGAAGAGATTGAAGGTTCCAAAGACGGCTGGCTGTGGCTCACTAGGCTAAATGATGCGTGATATTATTCGCTACGGCACGCCTCTATGATCCAGGTATAGCAGTCTCAACAAGAGTCACAGCCAACAATACTCCGCTCCGACTGTTTTGCGGCCAACTCCCAGAATTTCTATTTGAAATTCTAACTGGGTGTTGCAGATGGGTCGAGGAAATAAGATAGCAATAATAATTGTTACGTGGCAATTGTAATCCGTCAGATATCGTCTCGAGACATGTTGACTCAAGAATGTGAAAATGGACAAATTTGGAAAATAGGTAGCGGAAAATTTTCGCAAGGTTTGAAAATTTCGGTGAGCATGATACGATACGAACTTTCCTCTTGATTTTCGCAGCCCGACAAGCCGTACGCGTACGCAATTTGTCTACCGTATACCTGGACGTTCAGGCTCGTCTATCTCGAGATGGTCCAGGCAAGATTTTTGTGGGGCATATAAAAAAGGTCAGAAAATAAAGTCTAATATTTTTTGGGCCCTAGCTTGTTTCGTTATCACGCGCCCAAACCTGATCTACACTCAAATTATCAGTCGAACGCATTTGCATGGATGTACCACTTGGCTTCCGGGTCGTGAAGAATTTTGAATGGAAAATTCGTCTCACGTCACTCTAGTGAAACTCCGCTTCTATATGCTTAACTCATCAAATTGAATTCATTTTCGGATAAGGCAGTTGAAAACAGTTGTGTGTGTGTGAGTGAGCTCATCCTTCATAAAATGAATAGAGATAGAACACTGACACTCTCTCAAAGTCAAGAGGAATTAATAAATATGAGAGCTCATTAGTTGCTCTTCTCGTGACTACTAATTAGGAGGGTGGTGTACATGAAACAGTGTATGTGAAAAGGGTTCCCCGCCGCCGCCGGCCAATGTCCTTGGGTATATGGCATATCCGACGTGGTGTTTCTCGTTTTGAAGAGAGTATTAGGATGCAACGTATCAAGGAGAGACATAGTTCAAAGATTGGAGGATTTGAGATATATTAGGTGTCGAAATAAATAAGCAGGAAATAAACCTAGAAAACGATCTACTTAAATAGCAGTAGTTATTTGAGTTCTTACTGTAGTCTGTCTTCGCTAAGAGATATCGCGCGAATAAACTGCTCTACGTACGCATCTTCTCATGATTTATCCCGTAATATAAACATGGCAAACATTTTTAAAAATATCCTCAATGCTATATTGAAATTCAAATTAGTACAAAGAAAGCAATTTTTCGATTTTTTTAACGAGAAAACTAAGTTTTCATCGCTCAAAAAAAATATGTAGATTTTGATGAAAATAATATGACAATTTATTTAAACCTATATATTTTTTTCTCATGTCCAAAACCACTTTACGAAAAAAATTTTTTTTTAAATAAAATTATTGGATTTTACGTCAACTTTACTAGAGATAAATTCCGAAAAATTAACAATAAATATAGGAGAAAACAATCCGACATTAACGAAATTGTTCCCGGTTCTGATTATCTCGTACCCAAATCAGCTTCCATCACTGCGAAGAGAGGAATCGGGTGTGTCGCTCAGCAGCTTCTGATCGTCGATTTGTCGAGAACTCGGCTCACCAACATCGAGTAAGGGAATATCCGGATATTTTATAATTTTGATCTTTAAAAAATTTGCTTGTGAAAATGTGAAAATCTAAAGTGAAACCAATATTGGTTTTATTCCAGCTATTTAATACCCCAGTTAGAATACTTTGAGATTTTTCCGGTGAAAAATTGAAAATTCGAAAATTTAGATCTCAATTCAGGCAATAATCCTACGTGGCATCCCGCAATCCGGCAAATTTCGGTGGCTTACAACTCGTCGCAGAGCTCGATTTATCGCTGGCAACTCCATTTCCACACCAACTCGATGCTGAAGCCAATCGAATCGTCGACTTGACGTCACCCTACTTCCAGGCATGTTGTACACGTGAATTTGGCTGGAAACACGCTGAAAAGGGTGCCGGATGCGGTAGCCGAGCTGGCGTTGTGGCGTTAAATGCGTCGAGAAATGAGATTGAAGCCGGAAATCACAATCGTCGGTTTTTTAGTGGGTTTTCAGATTTTGTTTTGGAAATTTGAAATTCTGAACAAATTCAATTTTTACAGACAATTTTGCGTGAATTATTGATCATATTTGTTTTAAAAGAATCGAAAAATTTAAAACAAATCAAATCTCGCTTTTCATTGGAGAATACATGACAAAAGTATTTTGTTTCGAAAAAGAAAAATAGCCAAAATTTAATGCTATTTTTTTGAAAAACTTCGATCTTAATTCTCTTTTTGAAAAACTACTGAATAATTTCATCAAATTTGTTTTATTTTGATAAGATAATCACGTGAAAAAATGAAAACAGCAAAATTGAAAATCAGACAAAAGAATAATCAGATTTATGCAATTTGGCCTGAATTTTCAAAAAAAAAACTGGATTTTGGAAAATTTCATCAAATTCTGTGTATTTTCGTGCAAAAAAAGATAGCTATGAATGTCCAATTTTCGACCTTATTGAGAAAAATTCGTAAAAAATTGTAGAAGAACGTTTCAAAATCTCGATTTTCTTCTGACAATAATTCTCAAAATCTTCATATTTTTCCAGCCAGAACTCGAAATGCTCGACGCCTTACGACAAATTGTACAGTCTGCCCAATTGCTTCAAAAATGCGATACACGCATTGGGCTCACCTCCATTTGGAGCACAATTCGATTGAGAAGGTGACTGGTGGATTGCTGGCGTGCGACTAATTTTCCTACAGACGGTTCGTAGACTTGTTTTTTTTTTTTTTCGTTTTTTGAAAAAAAACACGGTGAAAAATAATAAAAGCGAGCCCAAAACATTTTTGTTTAAAAAATATGAAAAATTGTTCAAATTCATAGGTCCTCCTTCAATATTTTCAACAAAAAAAATATTCTAGAGCTTCCATGGAGGCAGCCGCGGTTTCAGGGCCGACGCCGACCTTTCGCCTCTTTTTTGCATTTTTACGGGAATTTTCAAATTTCAAATTTTCCCCATTTCTATCAAATTATTGAAAATCAAATTAAAAACGCGAATCGGCATTGAGGCGAGAGGCACGCAGAGGTTATTGCCTTAGGGTCAGACAGGCAAGCTTTTTAACGCCTAACGTAATTTTAAAACCTGAAACATAGAACTTCCCCACGTTTGATTCCTCTGAATTTACTGCACCTCTTCATAAACAATGTATTTAGATCAGTGTAAGTTTTAAAGCTGCTCTGCAGTGCCCAAATTAAGGACTTTGCTTTTTTAGACCAAACTTAGTCCTAAATAACCGAATTTCGTAATGAGACTTTCTGAAAATTTCTCGAAAAAAAGTTATGGCGGTTCAAAGTTCAGGAAAATAAGGTAAATTTTCAGCTAAAATCAAAATTTTTAAAATTTTTTATTTATCACTTTTTGATAAATATTGTGGTCTTTGATTAGGCGGGGCACCACTAAAAGTTACATTTGCCCCACTGACCATGAATGTATTTAAATCAGGACGAAAACGCCTAATTAAAGACAAATATTTATTAAGAAGTGATAAATATAAAATTTAAAAATTTTGATCTTAGCAGAAAATGGGCTTTTTTTTCTCAAACTTTGAACCGCCATATCTTTTTTTTTGAGAGATGTTCATTACGAAATTCGGTAGTTTTGGACCAATTTTGTGGAAAAAAGCAAAGTCTCAAACATTCGGTACTCCACCTTTAAAGATTCTATACTGTAATTTTTTTTTATTTTCCAATCAGTGCAACTCCAATACTCTACTTATTCGATTCAATAAACTCGAGGCACAGTGTTTTGAATAGGCGATCGCGTGTCAGGTTTTAACCAAAATAGTCATGATGACCTTTTGTTCACCTTACAGAATCTTCTCAGGTTCATGCACACACAGGTGTCATTTACTCTTTCAAGTGTATATGTGTTATCCCGGAGTATCTAAGATAAACGGTAGTTAGACCACCCTTGTGGTGCGCGTAAGTTGTTCGTATAATTGTAGGGGTGGGGATCTTACCACATTTATACGGCCCCCCTCCTATTGTATTGTATTGCTGCCACCAGTCGTCTTAGAGAATCTCTTTGATTACGGGGTGACAGAATCATACTTTTTGGAATGTGTAATAGGTGGGTCTCGAATGGATATTGAGCACTAACAGCTGTGAAGGGATCCGATGGTCTTTCTAGGGTAACTTTCCACTATGCAGTCAATATTATTAATCTTACAAGGAAAGGGTTTTAGTTTAATACTTTTAAGACATGTGTGATTTGAAAGTGTTCCATAAGTGTATGTCACTCTAAAATTTCAGGCGGCATAAGCTCTAGTCTCAAACCCTCTAGCATCTATCTGAAAACGTTTCAGTGCGTTTTTCACTACTTTGAGGCAAGTAGAATATCTCCAAAATGTTTTTTTTGCAAATCTTCAATGATTTTAGAACGTTTAAAAGAAGGAAAACAATCTGGGAAAATTTTGGAAAATTTTTAATTTTTTGAAAAAAATCTGAAATTTCTTGGACCTGGTGGCGTGAAGAAATTTTCAGATTTTATTCAAAACTTAAAAACTTTCCAAAAATCTCCCAGATTGTTTTCCTACTTATAAATGTTCTGAAAAACATTGAAGTTTTGCATGTTAGTAGGGAGCGATTTGGTAATCGTGTTTAAATTACGTTACACATAGATAATAATCAATTGAAATATACAATTCTTAATTCCATATAACCTGAAATTGAGATTAGATACCTTATACAACAAATAGAATGTCGAAAGTTGTCTTCAGCAGACCCCCATTTGTGAAAAATGCCTTCTAAATTTTATTTTACACTTCTCCTAGTAGATGAACAGCACCTGCCAATCATTTCCTTGACAGCCGGATGGTTGCTCCTCTAAGACAGTATAATCCGGTCTCCCCCGGGGGGATGTAGGGTGTTGTTGCAAATAGCTTTGCGGAGCAGGTGCTTTTTTAATGGATTTAGCTTATTGGTGACGGAAAAACCCTAGAATTGATACAATTTGGTTTTCAAGGGGATTTGGGGAAGGGTTTAGAGGGGAACTGAAACTTAGTAGATCTTCGTCTGTCGTGGAGATCAGAAGATTGGAAGTACTGGGTTTAAGGGGGTCAAGGAGTACTGTAGCGCATTTCGACTACTGTACTTTAGATAGTTTTGTTATTATATCAATCGGATAATATATAATCAAGTTGCACCAAAATTGGAGACATTCTAGTAGGCATTTTCTTTATGCTAGGTATGTATAAGTTTCTACTAAGTGTATAAACCTACTATGTACCTAGGGGGAGTAGAGTTTGTGGGTATTTGTTTGCTTAAGTGCAATAGACTATAAAACGTGTCCAAAACCACCGAATTTCAAACTGAGATAGAACTTCACAAAAAATTTCCAAAATTTTTTTTATGGAAAAAAGAGCAAAATTTAACTAAAATCCGACATTTGGCACAGTTTTCTTTGTTGTAGCACAGCCGCGGGATTTGAATTTCTCGGAAATTACTTTAATCCTACATAATAATTTATCTCGAAATTCGTTGATTGAGACAACTTTTAGGCCGATAGGCATCCCATCTTGATCAGGATGCCTATCGGCCTAAAAGTTTTTTAATTGCAGAAAAACTAAAATCCAGCTGTACTGTGACAAAGGAAAGTGTGCGAAATCCAGATTTTAGCAAAATTTGACTCTTTTTGTTCGAAATTTTGAGTCGCCATAAAAATTTTTGCAAATTTTTTGTGAAGTCTCATTATTAAATTCGGGGGTTTTGTACTAGTTTTCTAGTCTGTTTAAGCTAAAAATACCCACAAACTATTACACTTTACTTTAACACACAATAATTCACTAGCATGGTGTAGTATCATGCCGGAATTAATATAGGATTGATTGAAGAGCGAAATTTTAAATAGATTATTGCAGACTATCTAACACTATTTGTATAAACTAAATTAACATAGTGTATTGAATAATGACTTTATTGAAATTAATACAGTTCTTTTGATATCCCCATCTTCTATGAGTATCCAATACTAATATGTCATATGAATTTCACTTTAATTGTTATTTCCCATGCGTCGTGTTTATACAAATGCTTTATATACTCGAATAGTCTAAAATCCAATTAAACTCGAGCCAATACAGAATATAGAATGTAACAACACTTGTGTTAATATTCTAATATACATGCACACACACACCCACACACCGGTTTTACACCAGTTCTACTAATATTTGCACAATACCATTGAGATAGCTGAAGTTCCATAGATATGCACGGGTTCGTTTCCGGCACTGCCACGGAAAATATTGAAAATGTGCGGTTTACGAAAAACAACAGAAAAAGCGATTTTCCAGAGAAATACGAAAAAAAAGAAAATATTTAGAAAATTAACAACAAACAAAAAAATTTTTTTTTATTAAAGAATAAAATGTAGGAGTTCACTTCTTTTTTTCCCCTTTCGGTTAAACTAGGGCTTCGATGGTAGGCAGGCGCGCATTTCAGGCAGGCCTGCCTGAAACCTGCGCTACGCCGGCCTCAGGTCGCCTTAAGACGGCTCCTAACAAAAATTTGAAAAAAAAATTTCAAAAATTGAATTTCCGCGCTTTTCGAATTTCTAGAACGCTTTTTTTTAATTAAAAAAAAATTTCAGTTGGACCTTTCATCGAATCAACTTCGAGTTTTTCGAGACGAAGTACGAGAATTCAAAAAATGGAAAGAGACTTGCTGTTCCAACCACTCTTTGGAGCTCCTCGAGCCGTCGGGCCTTGAGCTTGAAATTGGGTAATCTAAATTTATACGAATTTTGCAAATTCTAAAAATCCTAATTTTTTCTAGAATCCCTTGATCTGAGTCAATAAGCTAGAACTGCCCTGCCGCAATTGGGAAAGTCTAGCAGCTGAAAAAAGTGGATTTGAGCCATAACTAGAATTGCGAAGGTTTATCAATTTGTGCTCAATAATATTAAGCAATCGCAAGCATACTGTTGATTTGTCGAATATCAGTTGCAAAGTGTGAGTTTTTTGTTGATAAAAATTATTTGAATTTTTTCTTTTTTTTTAATTATTAATTCTGAGTTAAAATTCATCGTAAGTTCCGAAAATTTCTAGAGTTGAAATTTAAATTTTTATCCAGAATTTAGTCGATTATAAAAACGGAAAAAATAGGGATTGTCGATTAAAAAAATTAATTTATTTTAAAAGCACACAGTTTCGATAAAAATTTAATTAAAATAAAAGTTCCTTGCTAAAAAACTATTTCCTCAATTTTTTTTCTGAAATTTCACTCTTTCATTTTTTAATTCTTTTTTGTCTATAAATACGAAAAACACGAATTTTCGATAAAAACGCATTTTTCAAGTTTTTAAAATAATTTTAACTTGGAATTGTTCTTTAAAAAATTGTTTTTTATCAAATTCCAAACACATTAATGCATTTTTTAAAAAATAATTTCTTTAAATCTTCCAAAATCGGTTGTAATTTTAGCGAAAATAACTATTTCTTTCAGTTTTTATTTAAAAAATCCCTCGAAATTTGAATTTATCCAGAATTTAGTCAATGCAAAAAAATATACGAATTTTCGATTAAAAAAATTAATTTATTTAAAAAACACTCTCGAAAAAAAAATTTTCAATAAAGAAACTAGTTCTTATAATTTTTTTTTTCAGATTCACTTTTTCATTGGCCTTTTTAATTCAAATTTGAAGTAATCTGCAATTTACTCTATAAATACGAAAAAAATACAAATTTTCGGCAAATGAAAAAACACTTCAAATTAATAAAAATAAAAAACATATACTAAAATTTTAAAAAATAATTTCTTGCAATTTTCCAAAACCTCGAAGGTTTTAATCGCAAATAACGATTTTTTCAGTTTTTATTCTTTTAAAATTCCCTTGGAATTTGAATTTCTCCAAATTTTTTCTTGAAGTTTTTAAAATTTCCATCATTTTCTATTGGAACTTTCAAAAAATGTTCCTATGGCAAAAATCTTTTCCGCTAATTTCTACGTAAAAATTCTGCCAAAAAACAATGACAGTTCATGTTTTTTTGTTAAATAAATAATTTTCTTGTTTCTATGGAATTCGATCTTTTTTGAGTTTTACCCCAATAAAATGTATATTTAATCTAAAAATATATCCCAAAATTCCAGATCGGCACTACATCTTCTCTGACTGTTCTGAACTTCATTCCCTGGACGTGTCGAATAATGAGATTTCACTGCTGTACAAGCTTTTGCGAGCAACAAAGCTGAGGAAAATTTCGATGAAAATGAATAAAATTAGTGAGTTGAAGCACGAAAAACTGCAATTAATATTTTGAAATTTTTGTGTTTAGAAACGAAAATCGAGATAATGTAGGCTTAAAGTTGCTCAAAATCCGCAGATTTTTTGAAATCGATTCTGAAAAGTGCACAGGGAGCTAAATCAGACTTCAAAATTTTCAAATTAATTGCATATTCACTCGAAACCCTCTGAAAACTGCCTTCAACTTCCTATATTAAATCAAATTTTCTTTCAGATCCCTCGACAAAGGTCTCGCACAGAAGCTTCCGGCCTCCACGTCTCGACGTAACTCATAACGAGATCCTCGTGCTGAAATGGTCGGCATTACCTGAAAACCTGGAGATTCTCAACGCTGATAACAATGATATCAATCCCATGACCGCCGTCCATGTTCCCAAGCACCGCAAACCTGAAGTCCGTTTCGCTTTCCAACAACGGCATCACCATAATGACTGCGGACCAGATTCCGAATTCGCCGAGTCGCTGGACGTGTCGAATAATCGACTTGCAAAGCTCGGAAGACAGCGTTGGCCGCGACAGTTGAGAAGGCTCAACTTGAAGGGCAATCTGCTTACCGTAGTGGCCTCCGAGTCGATAAAAGTCGTAGAGGCTGTGCATCCGTTGAAAGTGGAAGTCTCGGAGAATCCTCTGATCTGTGATTGTCAGATAGGATGGATGATTGGTGCGAAGCCAAGGGTCCTCATTCAGGACTGATCTCTGAAACCGCAAGCTGTTCCCATATATGGCCGGTGAGGCATCAGATACAGATTCAAAGTCTCAGCAAGAAGGATCTACTGTGCCCATACAAAAGTGTATGTGAGCCGAAATGTATCTGCTGTCAATACGGAAATTGCGATTGCAAATCCGTATGTCCCGGAGCCAATTACCGATGCTTCAGAGATCAGTTTATCAACATTGTCAGATGCCAAACATCAATGGTGCCCAAAAGAGAATTCGTGGTCTCCGCGCCCCCGGTCTCTGCGACAGAGATCATTCTGAGCGGAGTCACCCTTCCACAGCTCCGAACTCACAGCCTCATCGGAAGACTTCGTCACCAGAGGCTTCATATCAATGGAACCGGGCTCCGATCCATCCAAAAGGTTCCATACTCTTCCAGCACTGAAGACGCTGGATTGGCAGTGTCGGATAACTCTTTGATCTCGCTAGAGCGAGGGGGAATTTCTAGTGGAGAAGTCTCGCACTTTCAATGGAAATCGATTTCTATCCCGTGGAATCGTCGAGAAGGTTCCGAACTTGAAATATCTGGCACTTCATAACAACTCCCTCCGAAGACATCCCTAAACAGGTGCTTCACTCGACGGCGCTCTCCAAGATCTCCCTGTCATCGAACCCCTTGACATGCGACTGCTCGGGAGGATCCCAACAACACCTTCAACATCGTCGTGACCCATGAAAGCTAATCCATTCTGGTAGCATAATGCGGCCTAATTGAGTGGTTCTCGTTGCATCGGCATTTCGTTGATTTCTCCAAGGTTGAATGCTCGGAGAACGCCGCGTGACGAACTGGGCTTCCTGACGAACGATACGCCAGTGCTGAGCGCCTATCCACCTAATATGGGAAATGACGTCTTTGTGATGCCTATTGAAGGTTGGTTTATTGAAATTTTTAAAAAAACGCGCGTCAAATTAAATATTTTAAAGTCTTTGTTCGAAAAATAACCATTTTACAATATGTAGGATATATCTATAACAGCTTCTGTACAAACGTAATCCAGATGTTAATTTTTTTAAAAATGCGGTAAATATTATATTGATTACATATTATTATTACACCGGTGTATTTTGTTCCACTACTACGACTTTTAAGGGGGGCGCATTTACGCGCGATGGTCCCAGCATTAGTCTCGCCACGCACCCCAAAAATCAATGGGTGGCCCGGACACCATCGCGCGTAAATGCGCCCCGCTTTGATAGTCGTAGCAGTGGAAAAAAATTCACTTGTATAATTATTAGTCAAATGATACTTGCATTATGATATTAGAAATTAAAAAATTGGGTTTGAACATTTTTTTTCCTCAATTTTTTTACGGTATTTCACCATGTATGCGTTATAAATACAAATATGATCCCTACCTTTTTATAACTTTAAAATAACTTTGTAAAAAGGAATATAATACATGCACAAGCACCATAAAATTTCGACGTTTGCATTTTCTGGTCCGAATTTAGTTCAATACGTTTACTTTATATATCACATATACAAAACAATATACTGAGAATGCGTATTGCGCATTATATTGGACGCGCAAAATATCTCGGAGAAAACATACAGTAGTCCTATAAATTCCTACTGTACTGCTTGTGTCGATAGAATATTAAAATTGCAAAAAAAATTTAAAAATCGGCGAAAAAAAACCAAAGTATAAGGGAATATATTCAAGCTATTCCAAAACTTTAAATCAATTTCAAAAATCGAGCCCAAGAGAAGGACTTACTGTAGTTCTCCTACGATTTTGCGCGTCAAACATGTTGTGAAATACGCATTCTGAAGATGTAGTGTACTCGTAATATATATTTTAACAATTCAAACATTTCCAGAATTCCTGCGCGACTACAACTCAACACTTTGTGTTTTCTCATCTGGATTCTTTGGACAAGACCCTCAGAATAGTATACTCTTTGTCATAATAACTAGATTGCTGTTCTCCTCTGCGCCCTCGTTATTCTCGCAATTTTATTCGAAAATCTCACGACGCAATCAATCAACGAAGATAAAAAGCATCATCTCTAAATTGTGCAACATCTGCCGGCTCGTCGCCTCTTCCGGTTCCGCTGTTGAGTTAGCACTCATCTTTGTGAGCTATTCGAAGAAGGACGAGAAAAGGGTGATTCATCAATTGTGTCGACCGCTGGAAGATGACGATTATCAGTTGTGCCCGTTGCATCGGGATGTGCCGACTTGTTGCTCGAATTTACGCGATATCTGATGAACTCATAGCTCAGACGGACTCGTCGCTTGATTCTTGTGTTGACTCAACATTGGAAGTGGAAAACGCTGCAGATTAAAGACTTAACAAATTCAAACTTTCAGTTTAAAATTGCTACGTATTCGTAAAAATGATGTTAAAATTCCGAGAATGCGTGTTACGCAAAATATCTTGTAGCAAAAGCCACTGTAATTATTTTATATGACTACCGTTCAAAATTACTATCCAAATATTTGATTTTTTGGCATGTTTTAAAAAATTATTTACGATGGAATTTACTCAAATATTGAAAACAATATTATCGAAATTCCCGAAAATTTGGTGGAAATTGAAAATTTCAATTTTTTCGCTAATTTTCGAGAAAAAAAAAATTAAAATTTGGATTATCTGAAATAAAGTTCCCAAACATTAAATTAAAAATTTGTTTTTTAAACGTTGGATTTTCCAATCTCGAACCCTCAAAAATTGAGTTTTTTTGAAATTTTTTTTCGGACAAAGTAAAAAATGCTCGCAAATATCGACAAAAAGTGGAAGTATTTTTTTAAGTTGTAAAATTGTTGGAGATTTTTGCAATAAGATATAAAAAATCTGAATTTCCATTCAAATCTTGAACATCAAAATCAGCAAAAAAAATTGCTATATATTCATTCAAATTAAGATCTAAAAAGAGTAATTCGCTATTTCAAATTTTCAAAAAAAAAATAAATTTTAAGTTTTAATTTTTGAACACTATCAAAAAATTTGTTTTTAAACCTAAAACTGATAATTCCGAATTCTCTGTAAAATCTCAAAACAAACATTCCTAGCCAAATTTAATCGAATATGATTTAATAATACTAATTTTAAATCATATTCAATTACATTTCTAGGAATTATTTTTGCTAGTTAAAAGTGTATGAAAAATTAACACTTTTTGAAAGAAAAACTGTTCTTATAGGATTTATAACACCGGAAATTCACTAATAACACTCCACATTTTTCCAGACCTCCCACCAACTCTTCCGCCAAAAACCGTGCAAAACGAGGTGATCGCCGTGCTCGGCGACGGTGTGGACGCGAATCTGCTGGACGACGAGCTCGGACAGAATCTACGGAAGCACACGAGAATCTAGATGCGGAGCCATTTACGGTTTATGCACACTTTAGCACGCATCACTTCCATCACGACTTCGATTGCGCACATATCTCGAATAGTGGCGATGATTCGTCTCAACTATGTTCGGATTGGAATTGTGCCCGAGTGTTGTTTAGCTTACAGTTTTCCCGTTTAGGTCACAGAGTATTTTTTATCCTCTTCCAAATGTACGAGCTTCCATTATTCACTTTCTTTTTCACCCCCAATTCTGCTGTGCACAATTTGCCATTTTTTGAATTTTTACAACAATACCGGTACTATTTTTCGATTTTCTTTCTTTTTCTCGCATGAATCTTGCCATCACTTCTCTAATAATTGACCAGCGATTATATTTTTGATTTAACATAATAATTGAATATTCTCGTTTTTCAGTTCAAATTATTGCTTTCTGTGTCACCACAAATTCAAATTCTCGTCCTAACCTCGTGTGATCTTCAGTAATATATATAGATTAATAATCGTCGTTTCTTATTGTTGTCATTTGCGGATGCTTATGAAGCTTGTAATTTTTTGTTTTGTTTTTTTGCCTGTTTCAGCTGCAAACTAAAATTCGGTAGAAATTCTTGAAAACACGCAAAAAATGAATAAAAGAAATAGTATATTAGCTTTCGAGAGGAGTTCACAAGCGGGTGGCACATCTCCGCGGCCGCCCAGTGGTGTACTCGTCTCGGGTGAAAGAATTACTTTATAATCTGTTTTTCGGCCTATTTTTAGTTTTTCGCAACTAAATGAGTAAATTATCTCTTAAATAATGTCGAAATTAATTTAATTTACACTTCCAATAAAATTCCTCTCATTAAATTACCCCTTTCTAATGACTTTGCTCTCAAAAATTTTTCATCGATTTTCAATTCTCAAAATTCTTGAATCTTCAGCGAAGCTGGAATTCAGCAATCAGAAGAGGGAAATATCTGTCAAGAACAAGGTGGCGGGTGACAGTAAAAAAAGCGCAACGCATGAAGGCAGACGCTAAAAATACAAAAGACGGTGAGGATGTTCAGATCGCAAGGCGTTAGGAGGGGGCTTGGTGAGAGTCAGAGGACGTATCGTCGCTCTTCAGGGGAAAAAAAAAAGGAAACGGCGAAATTCTTGATTTTGATTTGTTTTTTCAGAAAAAATTGGCCTCCGGAGGGTGCAACACCTGCCAAAAAGTGAACGGAAGATTAACCGCAAGACAGAGCTTCCGTTCGAGAGAAGTAGGATTTTGTCGATCACTCCAAACAAAAATTGTTTTTTTCAATTTCAGCAAAACTGGACGCTCCGACTGGAAAACGCGGCTGACGTGCACCACTGCCCAATACATCACAAAAAAGAAGGCAAAGAAGATGTACAAGAAGAGGACACACGACGCACGCGACAAATATCGAAAAATGGCGGCACTGGCCGGAGACGGTGAAGATGACGAGGAGAGTGAGGCCGAGGTGATGGAGCAGGATTTTGGATTTTTCCGCGGCATTTTTAAATTGTTTTTTTTCCTTTGTTGATTTTGTTACTGTTTTTCAGTTTCGACATAAAATAATCGAAAATTTATTTATCACAAAAACTTTTGCAATTTGCTTAGCTGAGTGAGCCAACTGTTTGCCACGTGTCACGATTCGATGCATCCATCCTTTGGGCGCCTCGAGCTCCGCTTTCGGAGCCTGTTGTAAGCTCCTTTAGAATTATTGTCCAGACCTTAGAAATGTTCATCGAGTACCGGAAACTTCGACGAACTTGCACTTGTGTACTTTCAAGCAGGCTCCTGCCGGATTAAAATCAATTTAAAAATCGATCATTTGAATTTCCACGTGGCGCGACGCGGCACGCGTTGCATTGTTTTTTCAAATTTGGTTGAAAAACATGGTGCATCGAAGAATTTTCTTTGACGATTTTATACGCAGAATCACATTTGACGAACAAAAATTCAAAATACTTTACTTTGCAAACGCGCTCCATTGATAAACTTATGAAAAATCGATAATGCTCAGATTTCACCAACGAGAATTTTCCTCCATTTGAAATTATAGTTAAACAAAATTAATATAACCAAACATTACGCAGTTCCGGTAAAAATTTCGATAGCTTTAATGCAAGTGCGCTCAATTCTGAACAAAACCCACCCATCCTTTCGACACCACCGTATTCCGACAATTTCAAATCGATTTTATTCGCAGGCCAATCAGTATAATATTGGCTCCGCGAGCAATTTTTCGATACAAAAGCCGACTGAGCAGGTCTGTGGCACACACGAATAATTCTCGACTTGTCAACGTTGACACTATTGCGTACATTGTCAGTGATGACGCGAATGGAGAATGCTGAAAAAAAACAAGAGTTTAAAGGGTGAGCTCTCGCACCACGATCCATGTTTTTTTGTGGGAATAGTGGAAATTTGGAGTTAGTGAAAAAATCAAATTTGTGCAATTTTTAATAAATTCGGCAAATGCGCTAGAACATCAGATTTCACGAGCAAATTTCATTTTGTGAGATTAAGATATGGGCATTTGAACTGATTTTTTAATGGTATACACACGAAAAAAAATACATAAAGTCGATTGCGAAAAATTTTAGGTTTCACCCTCGGCATTGAAAGCGCAGTAGTAGGAGTGGCGATAGGGCGCCCTGCTAAATTTTCTATTTTTATGGTGTTTCCTTTCGTTTTGTGCTAATGAAGAGTTAAGAATCTGACGCGACAAACGTAATCGTGTCAACGCTAAGACAAACGAATAATTGTATTTCTCAACGGTAAAAAGATTCACTCCTGCGCCAAGGTGCCAGCAAGTGCGCCCCAGCCCAATTCGACACTATGGGAATAAACTGTGGGTTTAAAAACTTAGAGAAGTCGTTTTTGTTCAAGATATCAGCCTAAGATATTAAACACAAGCGCGTGGTCGTCAAGGTGTCCCGTTAATTCGCTTTGATGTACCAAAAATGCGGGATTTTAGACGCAGACTTCTCAGCATTCGTATTGTTAAGAGTGTGGCTGACGTCCCAATCATTGCATTTTTCTGCAACAAATTCCCGCAATTTTTGTCGATCAAGCAACACCAAAATGGAACTGTTTGACAGCACGTGCACAAGCAGATCACAAGTGGGATTCTCTTCGAGTTATCCTCCCCAAATCCTGTCCAGTACAGCGACCTCCAACGTGGCTTGCAACATTTCCAACTCGATTTGCTCGTTATTCAACAGGAGATTCATTCGATGAAGTGTCATCTCCCTCATTTGACTCATTATTGTATTGGGTGACGAGCCGGGTGGAAAATTGGTTAATTGTTGACATGCTTTCTTCCCGCTACCTTGATCCATAGACACGTAGAACCACATGTTGCATTGGAACATTCGACGTTTCTTGGCGAATAGCAAGACTGGACACGTGCTCGGCGATCTCATTCTTAAAAGTTTTAAATTGTAACAAAAATTTGGTTCAAAATTTCAAAGGAAAATCAATAATAAAGCTACTCCAAAGTTTTCAGCCTGATGGGTTGGAGAGATGAGCAAGTCCTACAGCGCTTCAAGAATTCTAGGCCACGGTCAGAGTGGTGGCCGTGATCCTCGTACTTATTTCTTTTAGATTTTTTAAATGGGAAACTCGAATTTATGTGAAACACCTAGAACATTCCAAGAAAAATTCAAAAAAACTCTCTAAGGAGGACATCGATAACCCTCCCCCAATTCGAGATGTGACGTCATCAAGGGGAGCCCGTGACCTCGCTTCAAATTTCAATTTTTCAACGAAAAGTGTGAGATTAGATGTAAAATTACTAGGAAATTAGAAGAAAGAGTAGAAAAGAAATTTCGGGGGTGTCGCTCACCACCCCCACCCCCCATTTTTCTAGTGTGACATAGAAAGTGGATCGGCCCCGCTACCTTCCATTGGGTTCAAGTTAGTTTTTTTAATTTTCCGATGATTGTATTACTGTAGTCACTGTAATTATGCGAAACAACTGGTTGTCCAGTGGAGCACGTGTGCTTAATTGTCCGTCACAATTCCATTCTTAATTCCAAAACTTCGAAGACTTCCCTCCGGTTGCCGTTTATCGACGTGTCTTCGATGTTGTTTTGGTGCATATGTAGATTGGTATTCCTGGAATATTAAGGGGAAAATGGAGAAAAAATTCTGAATTGTACAGGTAATCGAGAAAAAAAGTTAAGACTCCATTTTTTTCAACTAAATTTTTTTTTCAAAATTTCAAAAAAAAAATTTTATTTGGAAGAACTTTTTTATAATGTTCAGGATTTTCTAAAATTACCTTTATCTCTCAAAACTTGCTCAACTGAGTTTTAGATTTCTGAAATTTTCCGCGTGAAGTACGAACACTCCCAATATATCGAAGGACAGGCGCATTTGCGAACTAATCTTATTTAAAAATTTCACAAATTTATTTTTTTTATTAACCTAATATTTCCGTTTATCGTATTTTCTAAATTAAATAAAAAAATTGTCCAGGAGGAGTACATGGCCAATTTATCCGAAGAGCTCATATGCACACTTCCTGTTCAAAAACAAAAAAAAAACTTATTCACCTTGGCGGTGGGTACCTCTTTTTTACACGACGAGGCGAGTTTTCCGAGCTGAAAAATGATCCTTTTGGCTGGGCAGTTTTAGAATTGTGGGGAAGTTATAGGCATTTCCGGTGAAAAAAATTGTTTTTTATTGGAATAGTTTTTAATATTCTAGGCCATGTCCTAAAGACTTGAGTCAAGATCTGAATTAAATTTTTGAGGTACGAGCTTCCAGTTCCCTCCACAATTCCCCCTATGGCCTAGAATTTCAGAAAGCTCTACCATCGATTCAAACTGTTACCCGTTACTTTTGCACAGGTTACGGGTTCCGGACGCCCAGCCAAACTTCCGCCCGTGGCCTTAAGAACTCCCAACTTGTTCCACCGACCTGGACGTGTTGCTCGTACTGGCAACTCATCAACATCTGGCAGTAATTCAACCGTTGGGGACACGGTACGCGGGGTCGACGGTAGACTTCGGCGACTGATCGGCGATGTAGGAGGACTTCAAAAATCAATCAATAAATCAACGACACTCTGCTCGTTTTGCAAGGATCCGCCCATCCGCTTGTTGTTTACCAATTTCTTTTACAACAATTCTAATGCGCAAAATTAATAGAACTACCTTACTTATAATTTTTTTTTAACTCAAAATTTTCAAAAAAACGACACTCCGCTTGTAGAATCCGCCCACTTTCCAAAAAACAATTCGGAGTGTCGTTTGAAAAATATCCTATAATTTGAAAAACTCATTAGTCTCAAATTTTAATGAAAATTACGTGAAAATCTATAAAAACTACGCTTTTGGCTCCGCCCAAAAACGTCTTTTGGCACCGCCCGAAAACGGGACGGAGCCTAGCACTAATATTACAAGATGGTTTTTATTTCCATAAGTGATTAAAAAATCAACAAAATATTTAGAAAGTATCTCAATTATTGAATTAAATTTTATAAAATCTACGACACTCCGCTTGGAACCCCCTCCCCTGGGCTGCCAAGAATGGGGCGGAGCCTAGAACAAACGTTTTTACAAGAAAAATGTTTCTTGAAATTTTAAAGACGATTAATAAAAATCCGAGTTTTTAGAAAAAATTGGGCCAAATCGAATAATAAAAAACGTTACTCCGCTAATAAAACCAGCTCATTAACAAGATAGGGGCGGAGAGTATCCAAACGGAGCGTAGTTTGAAAAAATATTTTTTGGAAAACTAAAATGTTCCAGCGGGAAAGATTCTGCTAAAGGCAATCTAATCCAGGTTTTTTCCGGAAATTCAATTTCCTCAGGGTTCTCTCTGCAAATTTGTTCACGAAAAAACTCGTGTGTGCTGGAAATGCGCTCTATTGCTAATTTCATCCAGAGAGCGCTATTACATCAAAAATGGAGGGTTGTTGCATACCTTCTCGTTGCAGCGGGACTGGTGACGGAGGTGATAGCCGTGATGAAAATTGTTGGGGTATCGACAGCGCAGAAGGGAAACACGACGATTCGACATTTTTCTAAAAATCCATGATAAAACTTGTAAAGATAAAATAATGTAAAAGGGGAGGTGGCTAAGCGGGGACACAAATACGCGGGAAGTCCGCTTATTTTTGCTGGATTTGACGTAAAAACGAATCAAAAAACTGGCACTCGTCGCGTTTTGCAACAAGAAAAAACTAAAATTTCATATATTGGTGGCAAACACAGTTCGAAAACTGTTGAAGCTTACGTAAAGTGTGTATATTCCATATTAGAGAATAAGATTGGAAATGGAAAAATAAAATCTTGTAATTTCTACCACCGCATAACTTCTAAGTCACCTATGAAATATCTAAGCTACCGTGAAAATTCTAGGCTATCATAAAAATAAAATTTATATATGTTTGTCCTGAAACGAAGTCCACTTCCGCCAGAAATAATAAACAAAATAGACAACACAAAAAATTGAGAACTCTTAAGAACAAAAGAAATCCGACCCGAAATCGAATACCCAACGAAAATTTTCGGAATTTAGAAAGAAGAACTATGAGTTTTGGACACTTTTCACTTTCCCTTCAAAAGGAGGAACTTTGTGGCGCGGCCTAAAAAATATAAAACTCGGCCACCGATTTGTATGCGGCCACGGGACACTCCGCAGTTGCAAAGGGTAACTACAGCTGCAAATACTGTAAAACTAGGTCACCAAGTGGAAACCTTGGTCATCACGTGGAAAAAAACCTATTTGACAAAAAATTTTTGAAAATTTTATAAATCTTAATTCTAGGCCACCACCTGTCCAGGTCACCATGTGGAAGGCTAGATCAGCTAAGTGGATCGTAGACCAGCACATAGGCCTCTAGGCCACCACGCAGGAAATTAGGTCACTGGAAAGCTAGCGAGCCTCCACATGGTCAATAATAAGTCATTGTTAGTTGGAATTTCGTTTTGACCAGAGAAACTTGTTTTTACCAAAATATTTGAAAATTCAAGGCCGTCCGGTGAAATCTGTTTAACCCTAGGCCACCTAATTTCGAGAAAGTCAGGACATCTAAACTGGCACGTCACAACTAGAAAGCTAGGCCATCAAGCAAAAACCTAGAGCCCACTCTGCCAAAATAGATTCCTTAAAAGTTTGAGGGAAAAAATGTTTTTCAACAAAAATTTAATCGGCCGAGTGGACTTTAATAAATTCTACTTTTTCAGCCACATTGTGTGGCAGAGGGATATCGGAGCATCGTTTGAATTTTCTAATTTCTGAAAGAAAACCGGAACACATTGCAAGAATACGAAAAATATAACTGAAGCCGACATATGAAATGAGTTCTATGCTCCCCGCCGCGTATTCTTCTCATTTTTCTGCATATTTTTAGCTTGGCGGTGGGGTGCGAATGCTGGTATCATACTTCGTCCCCTCTTCATTCATTGCCCGTCTATGTATTAAAATTAGCGTGTATTCCTATTGGATTCTGACGGTCTCCCCGTCGTTTTTTTTTCTATGCGAAATAGAAAATACGTGGTGAACGGGAATTTTCATGAAAAAGAACGAAGAATTTGATTTCTAGGCCAACCAAAAAACATAGGCCAGAAAACGGATCTCTAGTAAAAACAACCACAATAAAGTTGAAACTAGGCCACCTACGAAAAATGGGAGATACCGCTTGTGTGTACAAGCATTTTTATAAAATTCTAGATTGTTTTAAAAACTTAATGTTTCCAGTACAAATCGATTTCCGTGAAAAACAATAAATATGTCAAACTCGTGACGTTTCGACCGTCAATAGAGCGCGTTTGCTTGTCAAACCAAACATATTCGGTGTAGATTTACGGGGTTTTCAGACAAAACAAAAAACCTTCACAAGGATCCGCGCCAAATAAGAGCTAGTAAATGGAACTAATTCCCGTTTTTTTTTTGTTGGTGAGTGTCTTGTGAGGAGGGGACCGCCCGTGTCTCTACCTAAAACATTGTTAAATTAGTGTGACGTCACCACAATTTGATAAACGACAAATATAGTTCGAGTTTTGAAGAAAAATTTTGGAATTTTTCTGGTAATAATTTGAAAAATTTCAATTTTTTATGTTTTTATCTTAAAAAATTTTTTGATATATTTTTAAATTCAATGTTTGATCGTCCTGATAACCAAATTTTCACACAAAAAATCTGGTTTTTGACGTCTAAATCTGCTTTTTTTCACCCAATTACGAGGTTCTCCGTGGGAAGGTGTGTCACTTGAGCTTTTGCTTTTTTATTTTTTTTCTGATTGAAAATGATTAAGCTAGATATACTTTCTCGTCTTTTATTAATCAGAATTGTATTGTTATTGAAGATTTTAGATTTTTACACTCCCGTGCAGCAAATGCGCTCCGATGTATGGAAATTTACAACTGGAGATTTTCAAAATGTTCATTTATAGGCTCTTTTAAAGGTTCAAGAGTCTAGTAAACTAGGAAAAGGTGAAGCTGTGACGTTATCGATGACGTCATCACAATTGTCGCTTGAAAAACTTGGAAAAACGATGTGGAAAGAGGGTGATTATTTGTGCTTCAAATAAACTTTTTGCTCTAATTAATTCATATAGTTGTGTGCTTCTTTAGATTTTAAGAGAAATTGCGAATTTTGCACCCAAAAAGCGTACTAGGCCGAGTAAGTTATGGGAAAACTCTTCCACATACCGGACACAAGACGTGGAAAACTAAAAGTTTCTGTAGTTTTTTATACCCCCGCATGGCACATCCCCGCCCCAACACTGTAAATTTTCAGGTGTTCAGGGTGAAAACATTCTTTCAGCTGCTGGGCGGCTTCTCGTGCAGCTGGAAATGTATTTCCAGACGGGTTGGAACCGGGATTTGTCATTCAACTGTTGCAATTACGCTCTACCGAGCTAAACCTCGTTAGGACTCCAGTGGACAACACGGGCCTTATTGTAAATTTCGCTTCAATGTCCACAATTTCAGAACAAACCGTCGCTTTTATTCCATAATATTATAATTTTATTTAAAGAAATCTGGAAACATTTATCGCTTTTTGTGAAAATCTATGTGAGATTATTGCCAGAAATACAAGAAAATCGATGCAAACTTGCTCTATTGCTAAATAGTTCGTGTACTATACGTCGACGACACGATTTCAAGTTTCGTTTTTTGAACAAATAAGCGTCTGTTATTATTCCAAAATTCGGTACATTCACTCAAAAAAAAACAATCATTGATAAATGTAGAAACATACATGCAACCACGGCCTCTCCGATGCAAATTTTTGATTCTCCAACTTTTGTTGTTAAGTTATCTTGAAAAAAAAAATGATACAACGAGAAGTCCTTGGTGGTATCGGGCGCCTAGAAACAGATGAAATGGAAAAACAAGTATTACGGGCGGCTCCGTCTAGGCGTATTATGGGGGGTGGGCCGCAGATGTTCCTTTAGAATAAGAAAAATGTCTAGTATTTTGTGATACTTGTGAAACATAACCCTAAACTTCACAAAAAATAAAGGGCTCAAAAATGGTATTTTACTAATGTAAGCCTACAAGCACAAAGGAAATCAATTTTTTCAATAGCTAAAAAATTAATTTTTGTGATATATAATACTTACACAAGTACCAATTTAGTTTTAAACGATAAAATATACCATAACTTTTGGGTAGGATCTGCACAGCCTCGAAAAAAACGGGATTTTCAACAAACGGAATAGTCGGACTTTTTAAAAACAACGAAAAAGTTTTGCTTGGGACCAAGTCTCATCGATTACAAAAACTGATTCTTCCAGTCAAAGATTTTATATACTCACGACTTAACAATTCTTTCGTGTTGCCTACCTAGCAAGTTCCGAATTCAGAAAAGTTGAATTTCCCTCCAACAATTTTTTACTATCATAGTCAGCCAATTTGCAATATTTCCCGCGACAAAATTTACGGATTCCCCACAATGGGTCTCCAACCAATAAAATGAATTATTCATTTATCTTCTTAGGTCACACGAGATGCCAGCGACCAAGACAGGGCAAGTGCGACCACTATCCCGAAAAAGACACCTACAGAACCTAACGAAGGCTTCCAAAATTAGCATAGAAAGAGACATTAGCAGAATATCCCACTTGATGTTCTGTCACTTTCAGCATCATTCTGCCTTTTTGTTCCCTTGTGTATGGTGACTATAATTTGATTGTGCTGAATATGATGTCTACTTGTGTTGTGGACAACTATTGATTTTTTCTGCTTTGGTTAATTTGAGGTATTACTTTTACAAATTTGTATATCATCATTTTACAAATTTCAACAGTGTTTCCTATTAATCCGCTAAACCGCAACTGAAGAATAATAAAAACTTTTCTCAAAACTGTATGGGAAAGCTCAGTGTCGGTTATGATAGTATTACAACATCGTTAATGCAAATTAGGTTTCGCAAAATTATATTCAAAAGATTTTTTAAATCGTTTATTACGGTACCAAGTAAAGTTGAGAATGCGTATTACGAGAACATATTTGACGGGCAATATCTCAGAGCAAAAACTACAGTAACTCTTAGAATGAATTCTGTAGCGTTTGTATCGATTTACGGGCTCGATTTTCGAAATAATTTATATTTGTAAAGTGAAAGCTATATTCAATTTTTCTTCGATTATTTGTTGTTTTGTTTTTGATTGTGTTTTTCTTTTATTTTAATAGTATTTGTCACTTTTCAAATAGAAATTGATAAAATGGAGCCCGTAAATGGACACATATCCAGTAGAGTCATTCAAAGAGTTACTGTAGTTTTCGCGTCATCTGAGATATTTTGCCCGTCAGATATGTTGTGCAATACAATGCGCATTCTCAACATTCCTGTTACCGTGAAAAACGAAATTTTTTGTTAAAACTATTTTTGTAAGTCGAACAAAATTCACAACTCGATAAAACTGTCCTAGTCATCAGATTAATATAATTGAAATAAATAATATGAATTAAATTAAATTTTAAATATTAAAAATGTTATTGTTGTTTTAACAAAACGTTATTGGACTTTTCAGCAAAAAAATGAAAATAAAAATCGATTATTTTTTGAATTGTTGATTTTTCGGTTTTTAAATGTTGTTGAAAAGAAACGAATTGTATATACGTCAATTAAAAAGGCCGTTTAAATTGTTTTTTAAAATGTTTTATTTTTTTCAGATAGATCAACAGGAGTGAACTTCATATACTTCAAAAAGCCAGTATGGGATGTATCTATCCAACCACTCTATCAGCCACTACTCTTAGCACTAATCACAATGTACGACCCCGTGAGAGATTGTTGTCTGTTTTTTACTAGATATCTACACGAGTGGTAGAATATAAAGAAGAGTGGTGACAAGTTTGGGATCTGAGTCCCGTAGAAAAAATCATCCCACCGAAACTCTAAACTATGAGGGACTGGTCAACTATGCATTTGACGACGTCTACCTGTTTTAAGTTATTGATGTGGTGAAGAGTGATTTGCCTTTTGAAGAAGTCGCTCGACCTCGACCTTCTTCGACCTGATTGAACTGAAAGATCCTCGGGAATCATTTTTAGAATTTAGAAGACTGTACCGACTGTGGATCTTTTTGTTTGCTCGAGACGATAGAATACAGCCCCATCCGAACAGGGGTGCGCGGCAATTGCCGTGTGGCAATAGAATATTTCGGCAATTTCGGCAATTGCGGCAACTTAGGCAATTGCCAAAATCGGAAAATTCAGAGAACCGGCAATTGCCGAAATTGCCGACTGCCGGAAATCCGAATTGGAAATATAAACTTGCTTTTTTTTTGTAGTTTTAAGAGATTGAACATGCATTTTACTAAACAATTTTCTCTTTTTAAAAATGGTATTTAATTCCTTTGAAGATTGACCGTTTTCTTTTAGAAAACTCTGACTGACAGAATATCACAAAACAATGTGACATTTTTCAATTTTCGATATACATTTTTGAAAATTGCCAACTGCCCTGCAATCGGTCGGCGATTTCGGCACTTGCCGAAATTGCCGATTGCCGGAAATTTTGAAAACCCGCAATTGCCGAAATTGCCGTGCACCCCTGATACCGAATGTATCTTAAAAAATTAATTTTTTTGTTAATTTTTTGAAAATTTTCATAAAAGTAAAGAAAGGGCCAAATTATGTTTCTTGAACTACTCGTAGTCTGTGACTTCATTTTCGGCCTTTTTCCGTTTTTCAGCAATAATGATTGGTTTTCTTTGCTCTCTAATTTTAAACATATTTCTTCACAAATGTCTCAAAATAACTTCAGTTCAAAGTAATAAAAATAAAATAAAGAGAAAAACATAAAGAAAAACCAGTGAGTTTTTTCAAAAATAATTCAAAAATAATTCGGTCCTTATTTTTTTTTTTTTGCAAAAAAAAACAAAACAAACTGCCCTATAAAAATTTTCCAAAAAAAAATTGGAAGGTTATTTTAATTTCAGCGGTCTATTTTTGGAAGTTGTCGAACTAATCGATCAAAACATTTTTTCATTTGTTTAAGTGTTATTATGCTTGAGATATTCAAATTCCAACATACCAGGCGTGATTCAAAATCATCGCTTTTTGGACATAAAACCGTAAAACCCAAAATTTATGAAAAGTTTTATTATGATAGAGTCATTCAATAATATTCCTAGTACTTTCACTAAATAATCAAACAATTTTTGTTGAATGGCTAGTTTCAAAATCGGCGGCTTACATAAAACATGCACAACAATAAGAAAAATAGGTATGACTTCGATCTTCAAAAATATTAAAAACAATATTTTTAATTTTACAGTGTTAGCAGTTCGACGAATCAATGCAGCTGAAGTACACTTATACAATCAAATCACGCTTTTTATATTAATTTTTAAATCAATTGAACCCATAAAAATTACAATTCCTCAAACCACGTTGATCCTAAACGACTGCATTAAGAAAAGGGAAAACATAGGGCTTCCCAAAATGACTGCCTCCCGCCTTGTGGCGACATGCTCCTGCCTCGTCCAGGCCGCCTCTCCAGTCAGTGCAGTGCAGAAATTTTTCAAAATCAAAAACATGGAAAATTAGAGAAGGATTTTAGGCCTCGGAAATCAATTTTAAGTCCTCTAGCTACAAAATGAACCGTTTTAGAGGAGTTTCAAAATTGTGAATTTTTAACAATTACCCAATTTTGCCACTTTTGAATAGGTTTTTGATGGTTAAACCTAGATCTTCTGGATAATTCCGCATATATGAATTACCGTATTTCCTAGATTAGTTTTGCATACAAGACTAATTTTCAATTGGTCTGTAGGGGTACAAGACTAATAGAGACTGCACATTTAGACTATTAGAGGCTAACTGCAAGACTAATTTTTGAATGCTATAGAGCAACGTGACCAATTTTTGATTGTAAACTCACCTTGATATCGTTTAAACAAAAATACATCCTATTGCAATATTTAATCAATTATTTGAACGCTTTTAATCAAAAACTCGAGTTCAATTTGCCCAAAATGGGTCCAATTTATTAACGTTGCAGCGATCTATGCAAGATATTGCTGGACTGGAAAAAATGGTCGGGTGCAAGACTTTTAGAGACTGCAATACTAATAGAGGCTGCAAGACTAATTTTCGATTTGCCCGTAGGGGTACAAGGGCCCATAATAGGGATGGAATACTATTAGAGGAAATACGTTACCTGTTTTTGACATAATTAGACAACATTTTATTTTTGATAAATTTTTTAGGGCTCCATCATTACTTCCTTTTTTTTTGGACAATAAAAATAAATTTTCTGCTTAAAAGCGTTTGAAACCACTATATTTTGCAAAAGGACAATTTTTTAGGATTGGAGATCAATTTTATGTCCTCTAGCTACAAAATTAACAATTTAGCGGAGGAGTTTCAAAATTGTGAGTTTTTACAAAAAATTGCCCAATTTCGCCACGTTTTTTATTTTGGTGGGTTATAGATTTTTTAAATTCAGCATATATGAATTACCCGTTTTCAACCTTAAAGTTAGACCATTCCTTGATTTTTGCCCAATCTTTTTTTCAGCCATCTTATGGCTGTTCTTTTTTTGGGCAAAAAAAGTACAATAAATTTTTCAGCAAACGTACAAAACCATTAGAAATTGAAAAAAAGCAATTTTTTAGGGTTCCCCGATATCAATTTTGGGTCCTCTAACTTCAAAAATGATATTTTCCAATAGAAGAGTTTCAAAATTGTTTTTGTGCCATAAATTGCACCCCATTGTTGCCACTTTTAATGGCCACTTTTTGGTGAGGCATTCCTAGATTTCCTGAATTCTGCATATATGAATTACCGTGTGTATTTCGACAAATTAAGACAACTTTTTAATTTAAAAAATTAAAAAGGATTAAAGGACGATCCGTTCTTCAATGCTATGCACTGCGGATCTGGGATTCAGGTACACTGCCTGGTGGTGATCCCTCTGGGCTGTAATTTAAGCCACGTTCTCCTATCCGCGGACTGTGGCCGATAATCTAGTCGTGGATTGGTCCACTTCCCAATAGAGGCCGTTAGGGTGAACCTAGGGAGTGAGGCCGGACTTTTATCTCGTGGCCCCCAGAATGCTTGCGGCCACCACTACCCTGAACTGCTATCTGCCGCCCTTGGGGAAATAATTTTTTTTTTTTTTGGGCAAATAAATAATTTTTTTATTGGAAATGGTACAATTTAAACCAACTACTATATATTAAAAAATATTATCCAATTATTCCAAAAATTCCAAATAATCCAAATATTCCAAATTCCAAATATTCCAACTGAATATTCCAAATTTATTCCAAATAATTTTATGAAAAAGGCCCTTTTGTTAGGGCTGGGAAGTTTGAATTTGGTTACAACTATTGCCCAATTTTGCCGCTTTTTAAACTGTGGTTTTTGATAGGTTAAACCTAGATTTTCTCCTGGGAATTCTGCATGTATAACTTACTTGTTTTCAACTATCTAAACTAGTTCAGACTACATTATTTTTGTTTTTTCAAATTTTTTCAGCCAAATTAAGGACTTTTTTGGGCAACTCTTTTTTTTTTTGACGGGGATCAAAAAAAAATTAAATTAAATTGCCCAAGCTTTTTAACAATAGTTTTTGGTCCCGGAAACCTAGCCTAGTGTGGCCCGGAAAATCGAAAAATCGAAAACGATAATTTTTTGAAAATTTTTAAAATGAAAAAAAACAGACTCAATTTTCTTCCAAAATAAAAAAGTGGGAAACATTTTGAATATCTTTCGAATAAAAAACATAACTTTTCAAAAAATTTTGATTTTCCCACAAAAAAGTGAAATAAGAAGCAGGTTACTGTAGCTGGGATAAAGCTTCAAAGGGTGCGTACCAGGACCTGAATTAAACCGCCGCCCGAGTAAATTTCATCGACATATTTAATGTACCATCAATCACCTGATCCTCCTCTTCCTCCTTCTTTCAACCATTACACCACACAGAGTTCCTTTTATGAAGGTCTCAATTCCCCTTCATAACATTCTTTGTAATTAATGCACCAACAAGCTATGCGAACAGCACTTAGACACCCCCCTCCTACACGCTCTTTGGAGCTCCCCCGTTCAACTCTAATGGACCTGGTAATCCCTTGCGCCGTGGGATTTTTCGGGTCTGGCCGTGTTTTTTATCCGATTTACTTCCCGGAATACCGGAAATGGCGATCGATATTGCAGACAAAGCAAACTTTTTATTTTCAAAAATCCGCCCACTTTTTTTAAAAGTGATTCAATCATTTTTTCTAAAGTTTTTTTTTTTGAAAGCCCGCGCTGGCTTCCCAAATATTTTGGAATGTAAGAGATTGCCGAGTTAGCATTTGGACTCGGCCACGGCCGGGGGCGATTCACGTCGGCTCGGTTTCTGTAGAAAACTAAATGTATTTGTCCGTATGGAGTACAAAAGCTTTGCCAGGCGTTATCCGGCAGGCGATAGAAGCCGCGACGCAACACGCAACTCGCCCTAAGTCTACCCCGGCCGTGGCTGAGTTATGCCTACTCGGCAAACTCTTGCATTTGAAAATAGGAGCGAAGCCGAAGCAGGTGAACATGGCGATGTCTGGCTTCCCTCATAAATTGAAAAGGAATAGAGTTTACCGAACTAGGCCATTTTGGCTCTGGCCATATCTGGGGGAGATTTACTACCGGCGCGTTGCGTGCCCCGTCGCGAATCAGCTCGTTTTTAGTTGTAAAACTGAATGTATTTGTACGTGTGGAGCACACGACTTACCCACGCGTTGTCCGCTAAAATGTTAATGGAGCGCGAAAAATTCAATGAGGAAGGCCAAGAACCCCGTGTGTGATTTTTGCAACTACAGCCCAGAATTAGAACGGGATTAATACAAATTTAGTTTGAAATTCGGATTTCGCAATTGAAAATGTTGACCACGAAATTAAAATTTCGAAAACCCGAATCTCATCTAAATTAAATTCCAAAGTTTTCATTCAAATTTCAATGAGTTCTCTATTGAGCCGAGTTCCCGCGCACGGGAGGTAATGGACCCCTCTTGTAAGTTTAGGGGTACAACGACCCCCCACCACCCCATATGCACAATACAGAACTCTCAAGACCCGCCAACCCTAGGCCCCTCATCCAAAACATATCCGAATATACCCTCTACTGTACTTTATTTACTTGCTCCGTTTTCCCGGGTACCAGGGTACTCCCTAAACTAAGTGAATTTCAAAGGTGGTGGCCTAGAAAAAGCTCTTCCACTGGTTGTGGAAAGAAATGATGATTCGAGGTACTTGTTGATGCCTTTTATTGCTTATGGTAGGGTTTTTTTGCCACGTCGTGTCCGGGCAAATTTTTAAAACTATTTTTCTATTTTTTAAAGGCCCAAAACTTTGTTTTTTTTAATGGTATCGTTTTTTCGAGAAAAAAATTACACAAAACGGGGGTTTTAGGTTTAGGCTAAGGCGTAGGCTTAGGTTTAGGCCTAGGCTTAGGCTTAGGATAAGGCTTAGGCCTAGGCGCAGGCTTAGGCATAGGCGTAGGCTATAGGTTTAGGCTAAAGCGTAGGCTTAGGTTTAGGCCTAGACTTAGGCGGCTAAGGCTTGGGCTTAGGCGTAGGCTTAGGCGTAGGCGTAGGCTTCGGCCTAGGTGTAGACTTCGGCTCAAACATAAGCTCAGGGGCTAAAAAAGGAGAAACGCCCACAAATTCAATCCTGAAAATTTTTTTAAATCTTAAAATAGTCAATTTTCAGTGGAAATCACAGTGAGCATTTTGAAAATCCAATAATTTTCAGTATTGCTATAAATATTTTCGTTCGGATTGGACAATGAAATAATCGGTGAACCAAAGCTACAATGCAATCCGGAAAGTATTACATTCTATTCTCCTTCAACACACGGAATCCGTGTATGTTAGTCTTGGGGTCTCGACACGAATTCTTCCCGCAAAATTAGTTTTCCGACATACTGAGTACCCCGCAAGTAGAGCGCTTATCAATAAATTATAAATAATCAATAGAGCGCACTTGCCCCAATTTCAAAATTTTCAGAGGACTTTTAACGTATATATGGCTTTTACAGAACACCCGGCTGTCGTCGGCAATTCCTCGCACCGAATCAGGCTGGAGGCTCATTTGGTAGGCTCGGTGATTGCGGGATGCGGCGATCCAATCAGGGGAGATTCGCCACATGGCGTCAATCAGCACTTCACTTTTAATATTGCGAACTTTCGAATCTGGCGAGAGGAACGTTCATTCAATATTCGATGCTTTTATGCACAGTGGATTGGCTGTTGTCAAAGCTGATCTGGATGTCAGGTAGGGAGGCAATCGATAAATTCCCCGAAAATTGATACATTTTCCAAAAATCAATAGATACCCAAAAAATCAAACAATTCCCAGGAAACTGGAAGAAAAATCTCAGAAAATCAATAATGTATTTGTTTTGCAGCGCAATGCCGGAAGAATCGTTCGAACGTGACAATCGTAGTATGCCCCAATGCACATATTCCCTTCGTGAAGGGACATTTGAGGGCCCAAAAGTGTCGAATACACGTGTGGGAATGACAATTGTTCATCCATGGGACTGTGATACATCGGGGAACTATGAAATACTGCTACGTGGAATGGACACCATACTCGATTCACGTGGTGTTATTATGAATCTTTTCCATTGCTTGATGAGAATGGGTAAGAGTAGGGAAGTATCGGCCGGCTACGAAAAGAAAAATATATCACTAGAGCAGGATTTCTAAGCATTTTTCTCAATAGAGCGCGCTTGGTCAAATCCCTTAAATAAAATTATGGTGCATCGAAACGGGTTTACGTACGCTTCTGATAGAGCTGTAGTACTCGAGGAAGCTGAAAAAAATAATGAAGAAAGTGAAAAAAAACAAAAGTGTGAATACAGTCGCAGCCTTCTCAGATAAATTTCAAAAAACTGTGGATGGTCGTAAATGGCGCGTGAAAAGTTTTTTGAAAATGGCCCTCGAGGACATTTCAAAAAAGAGCGATTTTCGCAAAGCCCCCTTCTTCGATGTTTGCTTTAGAAAAACAATGCAATTTTGTTTATTTCGCAACAAAATTTTTGAAAAATGAGTTAAATTTGCAACTGCTAAGAGCGCGATTGCACACACACAGACACACCCATCAAACGTCAGAGACCCCACTGATTTTGTAGATTAAGGTTGAGAGAGAACATGGAAAACGTCACGAACTTTGTTCCGTCAATTCCCGTTGGGTTGGCGCTTGATCATCAGAATGCAATGAAAGTCTAAAATTAAGCCGTTTCGCTAAAACGTAGCGAATCTCATTCCACCGAGTCTATTTTCGTGAGGCGGGTCTCCAATTTTTCAAGTCTTTGCTCGTTATGGTGCATCGAAGGGTAATTCAAAATTTCACATAATTGTTAGACACTTTCCGACCAGTTCCAAATTTTTTATGGTGCATCGAAAGAATTTTGCGTAATTTTGCAATAGAGCGCGGCCTATTACTACTCACCTCTAAATTTCTGCAAACTCTTCCAGAAGGTTTCCCGTGACTTCCCACAAGTGGTATACCTCCCATCACTGACGTCAGCCACATGGCAATCGAAGCCATCTCATTTCCTGACCAACCATCGATTTCTTTCTCGTGCCAAATTAAGTTGTCTGAGGGTTAGGGAAGTATGAGTTTCGGGGTATGAGTCCCCCCGCGTGTACCCCATTACACATGTCCCCATCACGGGACAAGTACCAATGCCACTTGATAATACAATTGGAAATACGTTAGGTGAGTTATTTACGGCCGAGAAAACCTGCAAGAATAAAAGTTCAGCCACCTTTTTGGCGGATTTTTGCGCAACTGTATGTCGCACAAGACTTTACGTCAGAAGCAGTGGGCGTGTCCGCCTGCAGGCCCCGATGTTTTAGATGTAAAAAATTAGATGTTTTAGATGTAAAAAATTGAAGTTTGACAAAAAAAAATTCGGCCACCGATTTTTTTTGCTTTCATGTTTTGTCCATGCATTTCCAATTTTTTTCGTGAAACGTTTTTGTCAGAATTGTGCCGGCGTGTCTTGTAAAGTCCCGCCCAATTTGTGGGCTTGTTTCGACCAAAAATACTGTTTTGTTTCACAAAAACAGAGCCAGATATAAGCATTTTGAAAAAAACATCCCTGTCCTCTCCTTTCTCCATTCTAAAATTTGAATTAGATCGTAAAAAACCCCCGGTCTTCAATTCCAGTGAAGAATTTGGCGGCAGAGCGTGTTTGCTTGTCACAGTTTTTTTGTCGACACTGAGCAAACTTCAACTCTGCTTCCAGCTAGAAATCCTTTACAAGCAAATTCAAATTTTCAGACGGAATCCCAAGCGACTGGAGCCGTGGATCAAAGAGCCCTGCTCCTCCCACTGATGACGTGGCAAACATCACCTCAGAAGGCAGAGTGCCTCGGCATCGTCATCACCGAAGAAGAACAAAATGACGAGTCGAACCATGTTGAGGCGCGAAAAAAATCGATTTGCTCATCGATTATTCAATATCACATCGGAAGATCTCTATGTGTCAGTGAGCCAACCGTCGAGCCAATGGAAGTAGAGATGCCTGGAGCACCGAGAGAAACTGGTCGGAGGGTGTCTGAGCCATGTGTCTCGGTTGAAACTTTCGATATTCGGCCCTTGCTGTACTTTTCGTTTTTGTCGTTTCGTTTGGACGGTCTGTTTCTTCGGAAGTCATATGCTTAAAAATTTTTTATTGATTTTTTTTCCTCCCACAGGGTTCTCACCTTCCTCATGCGGTTGATTTTTTTGCGCTCCATTGACACTCGCTTGTCGGAAAGAAGCACGCATGGGAAGGTTGTGTACACGGACAATGCGTATACATTTTACAATTTCTAAAATCGAGCCGCGCCGCAACACGCAACCCGCAAACCCAGCTAGCCGAGTCTAAATGGCCTAGTTCGGCAAGCTCTTTCAGTTCAATATGAGGGAAGCAAGAAATCCATTTGCCACCACAAGATTTTTGCGTGGCCGTCGCAGTTTTCTAGTTTCTCGGCCACGTTGTCAAAAATTATTTTAAATCGTACTGGGAAGACTAAATTAGATATCTCTCCTGCAGATTGTGATTCGCGGAAAAATTCCATGAATGTTTCTCCCAGTCATTTTTTTTTTGTAAATCCAACAAATCAAATGAGCGCCAAAACCTCACAAATCTCATACTCCAAAATTTGCGGAATTCCTCTTTATTTCTTAAGGCCTCCTCTTTGGAAAATTTAAAAAACTCGTATAAAAACTTTTTCTTCCGTTGCAGCATACGCACAGAAAGTCTTTAAAGTCTGAAAATAAAGTCCCAAAATCCCACTCTCATTCCACCGAGAGGTCATTTTCCGTGAGGTCTCTTTCTTGGGTCGCGACGCGAAAATACTGTAATTTTATTAATCTTTTCAGAACTCAAGACTGTGAAATGCCGATTCCAGCCAGAAGGATATTAGCTAAGCGAACAGTGAAACTCTTGTTTAAAAGTATTCTGTTTCCCATCCACGTGCCATAATTCTTGCATTTTTTTTTTCCCTATTTTGATTCAATTTATTTACAATTTGTTCAATTGCCTAAATAATCAGTAAATAATAATTTAACATTAACACAAGGCGTCACATTTTCGTATCACGCGTGGAATGTAACGGTGCCGTTAGTGTCAATGGTTCCGGCTGAAAATTAGTTATAATTGGAGCGCATTTGCATTTTTCTCGAAAAATAGATGTTTTCGTGTGATCCAGAATGATTTATCGATTTTTCTTAACTTAGTGGCCGAGAAAATGGAATCGAAACGGGCTCAGACCTCGACTTTTATTTACCTGGAACGAAAATTTAAAGTATGATCAACGCGCTAAAGCCTCAATTATGCAAAACGCTTTAAAAACGGGTTTTGGAATTTCCTCGAGACCACTGGTGACGTCACTCCTTTTCAATTTATTATTCTAACGTTGTTTTCTAGGCCACTGATGTCGATATTTTTCCACTGGTTTCTAGATCGCCTGCGATGTCATTTCTCTTCCATACCCTGCTCTAGCGGGTTTCTAGGCCGCTGAAGTAATTATTTTTCTTCCAAAAATAAATCTAGGCCATTAATGACGTTATCTCTAGTTCTTTTCCTTAGGATTCCCTCAGGTTCCTCATATTTCAGATCCATACTCGCCACGTTCATCTCATGAACTTTTTCCACGCTTTTTCACTGCTCGTACTCTTCTCATCTACTGTATCCGGCACCACAACGTCGGAGCAGCAGCTTGCTCATCAATATGCTGATGTCTCCTGGCGGACGTGGTGTATCTGGTGCAGTTTCATAGTGATTTTGCTGCTTCTCCATGAGATTCTGTATTAAACTGGCTGAGGGAGGATTACCACGAACGGTGGCATCGGAGGCGGCAGAGGAGCCATAGATACGGGAGTCTGAGAAGCCATCATGGAGTTGGGGGTAATTCCTTTGTTCGTTGGGAAATCTGTGGTGACATTTGTGGGGCCATAGGGGACGGGGACATTTGGAATACCATCGGAAGCATTGGCGGTGGTGGGGATGCCGGAGCCATTCGTATCATTGGAGCCATCACGTAAGATGGTGGAGATGGTGGGAGACTGGAAGGATTTTTTTTTTGAGTTTTTTTCGTAACACGGGCGTCTGTCCTTCCTCATTGCACTTTTCGCGCTCCGATGATAACTGCCGGACGACGCGTGGAAAAGTGGTGTACTCCCCACGGAATACAAATACATTTAGTTTTCAACTGAAAACCGAGCCGTGACACACGCTATCCATAAATGGTGTCCTAATTTCTGTTTTTTAATCTTGAGTTAAAAGTTTAATAATTATTTCTACAGAATGGCTGGGAATGTGACGACCCACGTGGAACCGAGAATTCTCCTGCGTGGACTCTTAGACAATTCAAAAAAATATTGGTGGTTTTGATAATAAAGGATTTATACGGATAAAAATCTATTATAAAAGCCGTGAAAAAATCATCATCAACCACTGCCTAAAAGATTGAAATTATGATGGCCGAGACTTCTCAAGTGTGGCCTAGGTAAAAAATCTTAAGGCCTTTGAAAATTTGCTCATTTCGAAAATTAAAAAAAACAACTCAATTGATAGGTTGTTTAAAATTAAAAATTAGTTGGTCTTTTTTTCTCAATTTATGCAAAATCAAAAATTATAATCAATTTTTAATCCAGAATTCGTCAAGTGGCCTAGAATTCGACTGCTCGGGTGGCCTAAAATTCCCCCAAAATTTAAAATTATTGATGCTGGCCAAAAAGTTGAATAGTGCCCGAGGTTGTTCGTATTTCACTTTTCTCAGGCGGCCTACGGAAAAAAACTCGGCCACCAATAGTTTTTCCTAGGCCTCAAATGCCCTAATTGTATGTTAATTACAGTATTTTCTAGACAAGATTTATTTCCTTAAAAAAACTCGCGAATAGCACATGGAGCTCTGACTCTTGCTCCCACCAATACAAAATTCCGAATTTTTTAGAAAAAACCGCAAAACTATAAGAATTTGTGGTAGAAATTGGGGCATTTACGTAATAACAATAATAATGTCCGCAAATTTTTTTTCATAAATTTCATAGTCCAGGACGAGGTAAGCCTAGAATCCATTCAATTTTATTGGGCCGCCGATCTTCGGAACACTTTTACAATTTATACAGTATACAACTTTTACCTGCAACTTAATAATATCATCAATACTTCCAGAATATTCTTCTTTTTCCTCTGGCTCAATTGCCACGTCATCATCTTGTAATCTGGTCCATTTTGCTGGCGAGGCGTCGGCAAACAGCATTTAGTATTTACGGAGCAAGATCTTTCAAGGCCCGCATGCGACAGGAACAATTACGCCAGTCTGTGAATCTGAAAAAAATAATCTTGTCTTTTAGGTGACCCTGCCTGCCAAAGTCTGCCTTGCAAGGGACCTTTGACCTACTTGACGTACCTTCAAGTGAGACCTATGCTGGTTTGCCTGCATTTGGGTTTTGTCAGTGCCTTCTAGGCCAATGCCTACCTTTCAAACTATGTAGGTCAACTGTTTTTAAGGTAGCCTGGGTCAGCGGTCACTATGCTATCTACGTCTACAATGCTACCCCGTGCCTATCTACCTGCTTTTAATGCTATCTGCCTTTTCAGCCTGATAGTTTAGGGACAATCTACGCCGGTCCAGCTCACATAGGTTATCTAAATGCCTATCGGGTTTCCTTCCTGCCTGGGCATCCAAAGTGACCTAGGCTTCGTGTTTTTTGTTCTAGATCTCACCGTATATACCTACTTACATGCCTGCCTTTAAGTTTACCTATGCCTGCCTGCATTCCTCGTGGTGCCATGAATGCCCTAAAAACTCACGTATCATAAGTAACAATCATATTGACGAACAACGGTTCGATGAGTTAATATCGTGCAAGCCCAGATCATGATCGGGTGAAGAGAAATCGTTGGCCTAAAAATTTACTCGGCCACCCCCTTACCTGCTGCATTGCGAAATAAGCGTACTGCTGGGAGTGCAACGTGGCACACTTATTGAATCCCGCCGTATTGCCCCATCACACTTTCGGCGAAAATTTGGAATGATGGAAGAGAATAGGATAACCAGGCCATGGATGTATGTGCGCTATGTTGATAATCGGTTATTTTCAACGTGGATTATCAATTGAGCGCAGTTGTCCCACTGGAAGAGTTTTCCTATCTAGGCCACCACCACCACCCACTCACCATTATAATAATAGCCAGCAAGTGTTGTTCATGTGGAATAAATGCTATAACGATGAAAAACACGGCGGCCACGGCCAGAGCTATTGTGTTGAAAATTTTAGTTTGCAGAGTTTCTGATGAACATCTGGAATATTGATTTTTGGTGGCCGTAGAGAGTAAAAACTCGGCGACTGAGTATTTTTCACATTTCAAGTATAAAATTATTCCAAGAAAAATCTGCTCCCGATAAACTCACTTAATATAATCACTAATAATTCCCGTAGCCATGAAAATTTCGTAAAAAATAGAAACATAATGGTAAGGCGGCCAAAAAACAGCACGAAAGTACGTCATAGTTCAAATAATTTTTCATATATTGCGGATTGAATTGGGATACCAATTGACCTGTTAAATCTCCAGACGTGCGATCCAACAAGGCCACAGGCTTAAACTTGTCAGAATATGACGGAAATACATGGAAGATTTTTCCTGGCCGGCATACCTGCCGAAAAAGTAACGGGCTGCGAATTTGCCCCCTCATGTTTTCAAATGGAAGAGGGTGGCCGTGAATAAAGGTAACCTCTACCGGACCTGGGTCGCGACTCGCGACAATCGGGAAAATTTTCTCAAAGAAATTTCGTACTCTCGCTACTTTTAGTTTTCCTGTTTATGGCATCCCCCGGGTCGAGGTACGCTTTTTTCACGGCCACCTCCTCTTTCCATAGTTTGAAAACATGGGAAATTCGAAGCCCGTGAAAAGTTAGGCCCAATGCGATGTGGTGGCCGAGGTTTTGAAAATTCGGTTACTCTCATGTAATAAATCTTGAAGTCGAAGCAAATTTGCGTACATCAAACCCATTTACCTCGTTAGCAGTTTTAGAAAAATTTGGGATTTTCTCATACTAATGAGGGAACGTCATAATTGTCGACACATTGCGTACCCCGAGGAACCAACTAATTCAGTCCTAGGTTTAGGCATATGGTAAGGCATAGGCTTAGGCGTAGACGCCTAGGCTTAGGCTTAGGCTTAGACGGGGTGTCAGAGTGCCTTATTTCGGCTTCATCTACGTACATCTACAAGAAGGGAGAAGAGACGCAGAGTTTTCTACTGATTTCGCAGACTTGGTTAAGAGTGTGCTGACGTCACATTTTTTGGGGCAAAAATTCCCGCATTTTTGATAGACCAAACCGTAATAGCACGGCCAGGCATGCGCTTAGCCTTGAGTCCGTAGTCCTTCGGGCGCGTTTTTCTCAAAAATGATACGTTACCATTTCAGGTTTTTCCGCTCCAAAATCTAGTTATAATAATTTGTGTGCCCGTGTAGAGCGCGTTTGCACTGACTTTCTTTCCCTCGATTTCCCTTATCGAATCCTCTCCAATTCCTTCTCGCAACCCCAACTGTGCTCACTCGGCGGTAAGGACTTGAAAAATCCCAGGAAAAAAAAAAGTGACCAACGATACCCCGGCGTTAGTAAACCGACGTCCATCCACCAGACGAAGAGCGTAATCCCGGAACTGTGTAAATATATTTGAAAGTTGATTTACGGTTAATAGTCCAATGAATACTTCGTGCTCGTATGGAGTCGCCCAATTATCCCTGCTGTAAGCCCATCGAGCCAGCGAGGGGATATGTGGCTGAAAATGCCATTCCTTGATAAATACGCGGCCACAAAATCCGAAGCCAATGGTACTTGCCAACGGGATAAGGGCTGTTGAATACTGGAAAAATTGCGTGCAATACATCATATTTGACGGGCAATTTTAGAAAATTTAAAAAAACGCGCTCTAATGATGCTTGGTGTACTCCTCTCGGACAATAAATGTCAATAATTTTCGAAAATTCGATAATTTTTGTTTAATTTCAGAAAAATGAAATCTGTTTTAGCATATTTTGAGCGCGTAAAATATGATTCTTAAATACTTAATTCAGTATTTTACGCAGGCGTGGTATCCGAGTGTCACCTCTCTAGGCTTGATCCTTGGTACGTAGATCTACAAAAAATGCGGGAGAAGAGCAGACGCAGAGTTCTCAACTGATTTCGTATGAGTTAAGCAAGTGCTGACGCATTCACATATTTTCGGCCAAATAATTCCCGCATTGTAGATTCAAACCGTTATGGGACAGCCTGACACCACGTGCTTACTCGGACTTTTTCACAATTTTGTGCTTCATGCACCATTTGTTTTTGTTTCGAAAAATCAGATTATTTAGCGGGCAAATGCAACGCCCACTGTGCAATACACCATATTTGACGATCAATTTCAAAAATTTTGTATGCTTTCGTGCTTTTCGGGGTACTGTAGCTTTGAAAATACGCATGCACTGGATCTGACGGCAAAATGCACAGTTTTTATAAAATTAGTCTAGACTAGAAATTAGTCAGTTTTCACGAAACAATGAATAAAAACTACAGAAAACTCGGCCACCGATATTTTTTTTTTTCGCGGCCACGATTGACGTCATACCTCATAATTCCGCCGACAAACCTCTGGAAACAGGATTATGCGGCAAATGTTGAAAAGAAATGGAAAAAATGGAATCGAGGCGGCAAGACTATAGCCACACACGATTGAAGAAAATTCGACTCTGATGGTTGGGATCGGAATTCACTGAAACAACTATTTTGGCTGGGCCGCCAGAGAAGACTCGGCCAACGAATTAAAAAAAAAACCTTTTGAAGTTGAAGTACTATTATCATCTTGCATACAAATTAAAATTATAAGTTCATATTTGAAAGAATCGAGGTCAAACACAGTGTGGCACATATTAAAATCTGCAAGAAAATCGTGAAAATTCAATTTTCCGGGTTTTGAGTTCAAAAACCAGAAATCGGACAGGAACCGGCGCGTTGACCATGGTGCATCAGCAACCGGAATTTTAAATAAGTAAAAAAATTTACGATGCTCTGATAACCAAAAGTGCAGTGATCCATTTAAGGGAAATACTGCTGGTGGATTAAACGTTGACACTGTTAACTTGATAGTTTTAATTTGATCAATGCTTGGTACTTGTTTTTTGCAGGAATCTTTGAAAATTGCCAAAACTATAATACAGTCTGAAAATTGATGATAATCTAAAACTTTAAATTCCGTTAATTATCATTATTTTTACGAAATTTTAATATAATCTCCTTAAAATTTAATTTTCTAGGCAGCGGTCTGTGAGCTTAAATTTTCGATTATCCCTCGCCAAATTAAAGAGCAGACTTTTAAGCTTATAAGCTTATTTCAGTGAGAGGAGAGCATTGTGCAAGAAGAGAAACGCAGACTAGGCTTGCGCGTTTCTCGTGCTCTGACGCGAGTCTCGATTTCCGTGGCTTGCGCATTTCTCGTGCGCGCGACGTTCATTTTTTTCCGATTTTTTTTCAGTTTTGCTGAACTTTTCTTTAATTCGTGATTTTTCATTTATTTTTCACCTCTTGTTGCTCGAAAATAAAACTGATTTTTCACACAAAATATTCGACTTTTCAGGTTCCGGCAACATGGGAGTCTTGTACTGAAAAACTCGGAATTAAGCAAAGTGGGACTCGTCGCCGGCGCAGGGCGTCAAACTGTCAATCGATAACGATATTTGGTCGACTAACAATGTTAAAGTATTAGTTTGTTTCCGTTTTTCCACGAAAATTTTCATTGTCAGGGCAGCGAACTGTATCAAAAGCTTCAAAAGTATTCCCGGCACCGTCGTCTTTCCGGAGCAGCTTTTATCGATTTTTTGTCTGAAAATGCAATTTTTTTCTAATTTTCAGCTCCCTGAAACACTCGAAGATGTGCAGCTGAAGGCCGGTGGAAAGTGGAAAAGTGCTGTTGACTCGGTAGGCTGCATTTTTGATACAAGAGGAAACGGAAAAATTTGCGAAAGGTGGAAAAAAGTCCTAAAATGGAGATTTGGCGCCGAACGTCATTCAAGAAATTCCATAACTTTCAAAAATCTATCTGAAAAATTGAAAAATATAAGACCATTTTCAGTCATTTTTAGTAAGTTTCAGCTAAACGTCGAAGAAAGTGCCTAAAACTAGGAAAAATATGAGAAAAAGACACAAATTTTGGAGAAAATTCCTGAAAAATGCAAAACACTTTTTTTCAAAAGCAAGTAATTTCAAAAAAAATCCCAAAAATTAATGCAAGTACGCTCCATCGCCCTTTTTTCCAATTTCTGACTCGAAAAGTCAAACTTCTGGTTTTGTAGGAAAGGTTATGCAAAACGCAATTTTTAGTCCAAAATTCCGAGAAAATTCTGAAATTTAAAAAAAAAATGCAAGCACACTCCATGGCACTCCGTTTCCTTTGCAAAATTTCGCGTAGATAAATTACAGACATTAGCAAAATTCCGACGATTTCGCTGACCATCACGGAAATATTGTAGGAAATTCAAACATTACACTTCCGAAAATAATTCCGCAAACGCGCTATCGCACTTTTCTCCAAGTCCCCACTCAAAAAGCATAGAACATACCTGAACTTGCCGTTTTTTTACACCAACTTCAAATTTACGCGATTTCGCTGCGAGACCCAAGCTAGTGCAGTTGCGCGCATTTCCAACAATTTCAAACTCAATTTTTTTCAAGTATTCACCACAATCGAGAACGTCCCATCAAGCGTGAACAGTGCAAGCCAGGATCGACTCATCAATAATAAATAAATTCCCCATAAAAATTATCGATTTATCGATTTTCTTTGACCCCCGAATCCTCTGTATTCCTTCGTTAGAATGTACTTTTTCCCTCCTCATTTTCTAGAAATATGTGTGTGGTGCAATTCTATGAAAAAATGCATTGCAATTTTTGACTTTAAACGAGACGTACGGTGCATTATTTTATTTTATGTACAGTTCCCGTCGTTGATCAAGTTACTCCACTGATATCAATTCACTGATAAGCCCACACTGACTGCCCAGCCCAACACAATTCCGCAACTTCTTCTCCCTGCTTTGCCATGAATTCGACGGTGGCTTCCCGTTTCTCATGGGGATTCATTCTGACCATGCGTCGATCGATTTTGTTGTCGTGTTGCCTACTGTTTGCCTGCCTGCATGATGGTTCAAATTGAATTTTACTCCGCAATTTGGCGTTTTTTTTTTAAGAGGTTCGATTGATTGGCCGAGTTAATTTTAGGGCACGAAAAATGAAAAATGAGCCGAGTGTCATTTTCGTTGGAATTCTAATTTTCAGTGTGTAAAAATATAGAAACCTCCAGCAAAAAATTTTGAACATCCCCGCCAAAACGTTACGAGACCCAAGTACAGCGAATGAGAGTTGCAAGAAAAAATTTTTAATGATTTGCAACTACGCTCCACAGTCCTTGGGTCTCACAACGTTGTAAAATTGTGGTATTTCTTCCATTACTTCTTATAATAACGATATTCGGTGGTCTCGACACTACACATTTTCATTAAAAATAAAACGGGCGCGATGTGCGCCTTTCAAGAGCTACATACTGCAGTTTCAAACTTTAGTGAAGTTGCTAAGCGTATTTTCAACAACGAATTTGAACTTACAGTACTCTTTAAGAGGCGCACGCCCGTTTTTATTAACAGAAACTTGTCGAGACCGGGCACCGTAGTTTTGACGCTAAAAATAAGATGTATGAAAAAGCGGGTTTTCAGAAAATTTCACTTATCAAAGATGAATTTGAAGTTTCCAGCCAAAATCGCTGCGAGACAGTGTAACGAGTGCAGAGCGCGAAATTGCTGTAAAATTTGATTGAAAAAGTTTAAAATTGAGATATTTAAAAACGGATTCTGGCGTCCCCCGTAATTGAATGAATTTCCCGAACTAGGCCACTTTGGCCGCGGCCATATGGGGTAGATTTACGGCGCGTTGTCGCGACCCGATTTTATGTTGGAAAACTAGGAATGTTTTTGCCCGTGTGGAGTACACGACTTTCCCACGTGTTGTCCTCTAGGTGATTGTCACTGCAGCGCAAGAAATCCAATGAGGAAGGCCAGAACCAAAAAGGACGCGTTTTTGAAGCAATTCATCGAAAGAAGACAGTAAAAAAAAAGTCAAAAATTCAAATATAGAAAAACCACCAAACCAACATCCAGCACAATCGACCTATTCTTGATGCTGCTATTTTTTTTGCACGTATGGATGTGCCGGCGGAAATCCACGTGGCCAAGAAGGCGGACACGTTTACAATGTGGGGTCGGTGGCCGACGCCGTGGCCTAGAAATCCAGCCGAAAAGTTTCCGTCAAATTTTCTGCCAATTTTCTGCTCGGCACTGCTCATCTGCGCGGCGAGCCCCACAAAATTCTTGCTCCTCCTCACAAGCTGAAGCCCGATGAGTTCCTCACTTTCGGCGACCCTGCCTTCCTTGTCTGGAATTTCGTTTCCGCGATCATTTTTAAGTCCTCGTGGACAAGATGCTTCTCGCGAACTCCGTCTTCATATATAATTTTGAGGATGAGGATGGAAGTGCCCTCCGCTGAGAGCCTAAAATGTAGTTTTTGATCACCCCCACGATTTTCAGCTCGAGGCGGCTCCAAAACAAACGTTTGAGCTTATTTTCCGCCTGCTCCAATACTACAAATGTGAATGGCTCTGGCATATTGTTTCTAAAGTCGTGGCTCTTTATTCATTCGATTAAGAGAATATCCATCGCGTCGGGGTTTTTTGTTTCGAATTTAAAAAAAAACACAAGTGGAAGAGTTTTTAAGATTTCTTGGCCACGCACACTCCAAAACCCGAAGTTTCAGCCCGTATCTTCGTTGTCCCTATTACACGGGACAAGTCATCGCTACCGTGGTCGCCACAAAATCGTACCCAGCCCTCTCCAACGCTGTCTACATCATGACAATCATCTCCTTGGTGAGCGCTGTCGCCGCCGGATTCCGAGGAGGATCCTTCGAATACGCCTCGCATACAGGATCCAGACGGCAATCCGCTATGATTTGACGGACTCGTGAAACAGGATCGCTTTCTATGATGCTCACAAGACCGGAGTGACTTCTCGTCTGTCTGCTGATTGTCAGACTGTGTCGGATACAGTTGCGTTGAATGTTCAAGGTTTCCTCAGGTAGGTGTGGGTGCGTGACCGAAGTTCCCAGATCACACCTAATTTTCCCAAATTCTTCCAGAAACTGCGTTATGCTCCTTGGATCGATGAATAAGCTTTCCGCCTCTCCCTCTTCACATTCATCCTCGTCATTATCTTCGTCGCCTCCAAAAGCTTCGGAACATATTTGTCATGTAAGTGCGCTCCAGCGAAAATGTTTTTCTAAAGTTTTGAACGGACCCCAAAATTCTGTCAAAGTGCCCCATTTTGGTTTTTGATCTTCGGAAAATGCCGGAGATAAGAGGCGCAGGCTTTGCAACTGATATCACATGGTAAAGATTGTGCTGACGGCACATGTGACGGAAAAATTCCCACATTTTTTTGTAGCTCAACGCACCTGACACCACGTGAAATTTTTGACAAGTCAAGAAAAATTTCGGCAAATGTGAATTAATTACCGCCGCACGTCGTGCCAGGCTGTCCCATTACGGCTTGATCTACACAAAGTGCGGGATGACTTCTTTTTGCCCAACGCGAATTTGACGTGAGCACTAATCGTTCTTAGTCATGCGCTAAATTAGTAGATAACTCTGAGTCTCTTCTCCCTCATTTCTTGTTGTTCTACGAGATCAAGTCTAAATTACCCAGCGTCTCTGTCACGTGCACGCCTCCCACCCTCCGACGAGCAATCAGCGGATTTACTTACTCAACTTGTTTTATTTCAGCTCCTCTCCGAAAGAACACAGGACAGAATTGCCGCCAATGTGCCGAGGAAGTTCTCTCCACAATGCGTACAGTCCGATCCTTTTCCTGCGAGAACGTCGACCGATCTTCTACGGGGAAGCTCACCCACACACTTGATGTTTGGCCACCAGAACCAAGCTAGCGATCGCCTATATCGGATTCCTCTGCTGGGCTTTTCCAGTTGTTCATTATTGTGTCAGTCCTCTGGTATGGAGGCCATCTAGTGCTGCACCAACGCAGAAAAAGAAGGGAGATCTTCTAGTGTCATTTTTGCTCTATCTCAAAATGCAACTCCGAGATAATCTTCGTCAAATGGTAGAAGTCAGGAGGCCACAGGATTGATGCAATCTGTTGGAGCAAGTCGTGAAGTGTTCGAGAACATTGATCGAGAGCAAATTCAGCACAACGGAGAGCATATGCGGAGAATGTTGTTGGAAAGATCGAGTTCAGAAATGCTCGCTTCAGTTATCCAACTCTCCGGTCCGATCAGCCAATCCTTAAGGAACTCTCGTTTACCGTTGAACCAGGAGAGACTGTTGCATTGGTACCAGCCACCCTGGCTGGAAAGTCTTCGTGCATTTCTCCGTTGCTTGAGAACTTCTACGTCCCGAATGCTGGACTTGTGGATGGAGTTCCGCGTTGCAAGAGTTCGAGCATCATTATATTAATAAGAAGGTACGTTGGCGTCAATTTCGGTTCGACAAATCGTTTGCCGGTTTGCCGTCAATTTTAATTTTTGGCATATTGCCAGATTTGCCGGAAGAGTTTAGAGTGCTTTTTTATAAGACGGAAACACTTGAAACTGTGTCCGTTTTTTTTTGTGCCGGTTGGCGATTTGCAAGATATTTTCACCGGCAATGTGCCTTGCCGATTTGCCGGAAATTTTCCATTATGGCAAGCTGACACCGATATGCCGGAAATTTTGATTTCGAAAAATTGCCGAGAGGCCGGAAGTTTCAAGGCAACTCGCCGATTTGCGAAATTTCAATTCCGGTAATTTGCCGATTGGCAGGAACAAATCGTTTGCTCGCAGTCTATTCGGATAAAAATTGCGCCAACTGGTCATCCGTTTGCACAGAAAAAGCATCTCCGCGCTTCGCTATTGGCCAATTTCATAGGGCAAATGTGACGCAACAAATCACGGGTGTTTCTTGCTTTCCATTGCTGAAACTGTGACTGGTTGGGCCCAATTTTTTGAACTTGACCTAATTGCGAAGCGAAGACTCTGGACGCAAGAAACGATTAGCTCCGTTTTCTCCTTTAGATCGTCTGTCGATCGAGATTCTCTGCTTTAAAAACACATTGCCCATCTTTTCAAAGCCCCTGTTTCAGCAGCTAGTAACAACAAAAAACCTCGAAAACTTCCAATTTTTCAGTTAGCCTTTGTCGGCCAGGAGCCCGTCCTGTTCGCTCGTTCTGTTAGATAAAATGTCAGAAGTCTTACGTACTGTGTCGAAGTGGCGGACGGTAAGCACGATTAAATGCACCATGAGCCGACCAAAAAAACTTGTTCAGGAAATCATTCGCGTGAATGGCGAATGCTCACGGATTCACTAGAAAACGTTGCAATACGAAACGTCGGAGAGAAGGGAACACAAACGTCCAGTGGTCAGAAGCAACGTGCAATTGCTCGGGCTTGTTCGTGAGAGCGTTTCTCTTGTTCCGTGGATGAAGCCACGTCGGCTTTGGACACTGAGTCCGAACATCTTGTTCAGAAACTTGACCATATAAGAATTTGGATGTGGAAAGAGTGTCATTTTGATTGCACATTATTGACTGTAGAGTAGGCTGATAAGATTGTGGTTATTAATAAGGTGAGTTGCAATTGCGCTCGAGGACCGAGTTTTGGTCGCAAGACACGGGGTTCTGGCCTTCCTCATTGAAATCAGTCTTCCGTCTATTGACAATCGCCTGCCGGACAATACGCGTGGGAAAGTCGTGCACACGGACAAATACATTTAGTTTTACAATTAAAATCGAACCGCGAAGCGACACCGCGCGCCGTAAATCTACCCCAGATTGTATGCGTGAACCGAGGCAAAATGCCCTAGTTCAGCAAAAACTCTTCCATTTCAGTTCGTTATGAGGGAATCCAGAAATCGGTCCGAGGGCCCTTGGTTACTCGCGGATAACGTGCTGTCAAATTATTTCAGAATTGAGAGTTTCGCTAAAAACTGTAGAATCGCGTTAAAAATGAGAGCTCACCAAACAGGATTCACGAAACAAGAATTCACAGAAATAGTATTCAGTGGGCGCAGTGTGCGCAGTGTGCGCGGGGTAAGCACACTACTTCTGGTCCCGCCCGCTAAATCCCGTGTTTCTCGTGAATAGCTGAATGAAATATCAAAACTCGGCGAGTTGTTCTGTGGCCGGCACACACACGTGGTTTCAGGCTGTCTCATGGCCCGACAATGGGTACATCAGTGAAAATGCGCTACTGAACAGAACGCATAACGCACGTGGTGCAAACAGGCTGTCCAAAACCATAATGGCTTGACCTACAAGAAGTGCGGGATGTTTTTGCCCAACAAATTTGATCAGCACGTTCTTAGGCATGCGAAATCAGTTGAGAACTCTATGACTCTTCTCCAGCATTTTTTGTTGATCTACGTAGATCAAGCCAAAATGAGACACGCTGACATCACGTGATAACCTGGTTGATACTACGCGTACGGCTTTCCCGGCGGGGCCGTGTTTCTCATTGCGGTTTGATCTACAAAAATGCGGGGAATTTTTCCCCCAGGAAAGTGTGACGTCAGCACACTCAGTCTGCGTCTCTTCTCCCACATTTTTCGAAGATAAACCAAAATGAGACATTTTGTCACCAACACACACACACACACACACACACGCACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACATCATATTTGACGGGCAAAATCGGCCCCATAATTACAGGGAATAGTCGAACACATCGGAAATCACGAAACCCTACTGAACCCCATGAACGGAATCTGCCCTACGCAAAGCTCGTTCAACGACAAATGATGGGAGATCAGAAGCCACGGAGGCCGGCGGTCGAGCAGCCACATCCCGGTACCTCAGCGCCGCGTCAACCAACGTGGCTTGCAGGACCATCGCAGGGTAATGCAATGTCCCTGTTTTGTCGACTTCTTTAAGCCAATCTGCCAGTAGTGTTACTTCTCATGATTAATTGTTTTTTGTTCTTGTTAGTAGCCAACATTTTTTGATGGACTTGTTGGGATTAATTTGTAAGAATACCTAAGGGATACAATTATTCATTCATTATTAAAATTTGGGCACACAAATTCGATTGTGGAAAAACTGTACAAAAACATTCTTGCAAAAACGTGGAAATTACTCAAATAAACTCCAGGTAGTCGTTGTCGACATCGTCTCGCTTCCGCATCGCTGAAAATCCATTTTTCACTTTTTTTAAAGCAGATGCTAACCGGGGCCTCTCCGTGACCGGATCGTGTTGTTCCATCCGCGGATTATGAGAGTAGGAGCTTATGCCACGTGTCTCATTGGCAGCTTGCCAATTGTTCGCAGACAGCCTGTACGAGTCGGTCAACAGTGGACCGTTTAGAGTCTGAAAATATATAACGGGAACACTAAAATTTTAGAAGCGTATTGTGCAACACATTTGACGCGCAAAGTATCCAGGTAGCGAAAACTACAGTAGTCCTTTAAGTGACTGCTGCACGTGGTGCCCAGCAGGGCTGGCAATTTTTTGGTTCTTTGGTTTTTCTGGTTTTTTGGGACCAAAAATCCAAAAAATCAACAACAAAAACAAGTTACCGTGTCTCTCGACTCGAGACTATTCTGTATTAACATACATCGAAACATGTATTTTAACACAGTCGTCACGTCATAACCAATGAAATACATTTGGCGACATTACTTGATTAACCCCAAAACACCTATAAAACATTTTCTGGTTTTTTTTTGGTTTTTGTTCCAATTTCAATTTTTTTGTTTTTTGGTTTTTTTGGTTTTTCAAAATAACTTCAAATTTTTGTTTTTTGGTTTTTTGGTCCAATATTTTTCTACTTGGTCCCTGGTGCCCAGCTGTCCCATTACGGTTTGATGTACAACCAAGTTAGAATGCGGTAATTTTTTGCCCGAAAACATGTGACGAGGTCAGCACGTTTTTAACCATTGCAAAATCCATGCTTCCCTATTGTTTGTAGTTCAACGTAGATCAAGCCGAAAGAGACACACTGTGAGCGCGTGCTATTGTAGTGCTTGTGTCGATTTACGGGATCATTTTTCGAAATGATTATACATATAATAATCGATAGAATAATAAAATTATGGAAAAAATAATCGGAAAATAATACGACAAAAAGGAAAATTGAAAATCGCTGTCAAAATTCGAAAAAATTAATTGCGAAAATTGAGTTGCCGTAAATCGACACAAGCGCTACAGTAGTCATTTAAAAAGGATGGTCTACTGTACTTTTCGCTACGAGATATTTTGCGCGTCAAATATGTTGCGCAACACGCATTCTCAAAATTTTAAACTCTCCGCCTATCACAGCTGTGTCTCGTTAGCCCTGTATGGGGGCGGATCTTTCAGCGGTGGAGCCCGATAGAAAAAATATTTTTTCTTCGATTTTTCAGAAAAAATATCGATTTTTTCCGATTTTTTAGAAAAAAAATTTTTTTTTTTGATTTATCACAAAAATTATCGATTTTTTAGATTTTTCATAAAAAATATCGATTTTTTTTTCAGATGTCCAGAAATCCATTATTTTGATTTATTTTTAATGTTTTGAGTTCCATTTATCTGAAATTTTTTTTACCTCATAATGATTGCCCTTTTCTTCCACTGCCGCCTCGCTTAGTTCAGGGTAGTGTCGAGTAATTCGTATTCGATACTGTGAACGTGTAAGCGACAGTGGAATAACCCGGTAGATCATAAGTAGTACAATATGGCAAAGTGGATTACTAACTGAAAATTATTGGATTTTTCTCAAGTAATAAAGGTGGGGAGATCCGAAATATGTGAAAAATATTTTTAATTAACAAATTTTCCCCTGATTCCCAATTTCTATATGAAAAAATTCAAAAAAAAATTTTCCAGATTTTATATTTAAGCTTGAAATCGCTTGAGCCCGCATCACTATTTACAAAAGCTTCCCCAAAGAAATTTGAGAGCGCGCTTGCTTAGTTTGTTTTTCTGCTCATGCTAATATTGTATTTATTACCGCCAAATTCAATTTAACCGGTTTCATTCATTTTTGTCGAAAAAATATATTTTTCAGGAAAAAACCGGTGCAAAAAAACCAAAATCGACAAAAACTAATGAAATGCTGGCTGCTAAAAATTGAATTCGGCGAACCGAATAAAAATAAGTTTTAAATGAAGAAAATTCTATTAGGAGCAAACGAAATTCGCCATTTCAAGCTTAAATATGGGATATAATCAGGGATTTTTGTTTTATTTATATTTATTTCACAGCTTGATTTTCTCAGGGAAACATTTGGGGTTAATATATTTCACAGATGTCGGTAAGACAAATATGATTATTTTTTTACAAAAAATAACCCCCACCAGTAACAGCGTAGATAAATTGAGATAAATGCATGATTAACCCGGAAGAACAAAAGTCGGGATTCTGTTGGGCAATGCTGGAGTAGAAGATCGAGATGCTTGTACAATAGTAGGGCAGGAATGAATCAATCATCTGTAATTTATTTTTTTAAAGCTGGTACAATCCACGTGGTTCAGAGTGTCTCATTTCGGTTTCCGAGCTACTGTTTTGTAGATCTACAAAAATGCGGGAGAAGAGACGCAGAGTTCTGATTTCGCATGGTTAAGAACGTACTGTCACATTTTACTGGGAGACCCCCAAAATTTCGCCGCTTGTAGATCAAGCTGTGACGGGACAGCTTGGCACCATGTGGGTGCCGAGGGGAGCTTTTTGGTATTTTTTGGAATTTCTCGAAAAAAACTTTCATCGATTTTTTTGAAACTAGCTCTTTTAGGTATAGAAGAAAATAGTTTTTTCTCATCAACGCAATTTTTAGATCAATATTTTCGATTATCCGGTGAAAATTGAAAACTTTCTTTTTCTATGTTCCATTTTGATTTTATAAATTTGGGAAAACCTAATATTTCGATTTTTTTTGAAAAAAAAACCAATTCAATAATTTATATATTATAGGCCACTCTTTTTCTCTAATTTCTTCTGAAAAACCTTAACAAGAAATTTTTTTTTTTTTAAACCAATTTTGAGTAATTTTTTTCTGTAAAACATACGATTTTTTTCCAATAAATTGCTAGTTTTTTCTCTCTTTCGGGTACTTGGACTGTCTCTAATTTTGCTTGCTTTTTTCTATATTTTTTCTGCGATTTACGATGAAAAGTACCAAAAAGTCGGAAATTGTTTTTTTTTTTCGATTTTTTAGGAAAAAAAACGATATTTCCTATAAGTGTTTTTTTCATAAGTAAATACTTTTCTCCTTTTCCTTTTGATCTACAATATTTCGACTTTATTCTGGAAAAAATTTTTTAAACGTTTCTTTCTGAAACAATTTTCAGACCCAAATTTTCAATAATTCAATAATTTTTCTAGATTGTGCGACCGAAATATACACATGGTTTTCAATAAATTTATAGTGTTCTCCATTTTTGTTGATTCTATTTTACTACTATAATTTTTTCAAATTTTCGAAAAAAAACATTTTTTTTTTGGAAAATTTTAATTTCAATTCGATATATATAAAAGTTCATATTTTCATCTTTCATCGAAATATATATTTTTTGATTTTTCAACCTTTAACTTGTTTCATTTCCTTCTCTCTGAAAAAATCGGAAAAATTAACAGAAAAATCGAATTTTTTAAAAATATATTCCGATTCGCCCTACCATAATTTTTATGACAAAAAATCGGTGTGCTCGTTATTTTCTACAAAGACTCAAAACCTCAAAAAACATGCTGGGCAACGTCAAAATCGCTCGATATCGAATCTTCAGCTCAGTCTCATACCAAATACACCGCATACAGAAACATCGTGCAAGGAGCTTGAAGAAGAAAATGAGCGCGGTAGATATGCACACTTTTCCACGAAAATTTCGGCCGAAATCATGAAACAGGCGTGGATTGAGCACAATTCGATGGAGCCAATAGCCGGGAAGAGCAGCCGAACCTTTCATTGGGATCTGTGTACGTTCGTCTAACCGATAAATGTTCCTGCATTGATCGGATACAGTAGACGAGCAGCCGGACAAATGTATTTTGCAAGTGGGATATTCTGAAAATTTTTGAATTTTTTCCGAATTTAAAATTTTAGTTTCTCGATTGTTTTGAAGTAAAAGAATTGATTTTTTAGAAAATTATATGTTTTGTTTAATTTATTTAAAAATCTTTGAGGTAAAGCGCAGTGGAGTAGCGCTAGTGGGGACTTTAAAACTGCCTACGATACCACAAGGACCGAATATCATGATAAAAAAATTCAAATGGAAATTTTTCTAAATTTTATAGGTTTTTTTTTGAAAATTGAACAATCTCAGTTGTTTTTGCCTAATTCCAATTTCAATTACCGCTAATTTGTTCGGTGGAGCGCCACGTTTTTATATATTTTTAATTTTTATGTTATTTACCACCGATTTTTAATGTTTTCGGTGTATTTTTGCTCGAATTGAGAAAAAGCAAGACAAATGCAAATTTTCAATTAAAAAGCACGCTTACAGGCGTAAAAAACATGACAAAGTGCCGATTTCGATTTCCAAAATTAATTAATTTCATTGATTTACGAACCTGTAATCGTGCCGCTTTTTTAATTGAAAATTTGCATTTATCTTTTTCTCTAAAAGATAATTCGAGCAAAAAAACGAAAACATTAAAAATCGGTGGAAAATAACAAAAAATAAAATAAATAAATCTTGTTAAAAACGTGCAAAAAATCACGCTCCATCGAATGAGCAAATCCAATTGGCGGTAATTCAAATAGTAATTAACAAAGACTGCGATTTTTTTCAATTTTCAGAAAAATCGTATAAAATTAAGAGTGGTAAATATTTAAAAAATTATTTTATCATGATATCCGGTTTGGTACCGTATTTTAAAGCAATTTCCCCACTAGCGCTACTCCACCTTTAAAGTGCTAATGAATTTTTTGTACGTGGTGTCAGAAAGTCCCATTTCGGTTTAATAAAAAATGCGGAGAGACGCAGATTTCTCAATTACGCTGCTATCGTTAAAAACGTGCTGACGTCACATTTTTTTGGGAGAAAAATTCCCGCATTTTTTGTAGATCAAACCTTAATGCGACAACCAGGCACCACGTGTTTTTACAATTACACATTATCCTGGAACTTTCCAGAAAATTTGAATTTCGCGCCAAAACTTAGGGGTAGGTCCCATCATGATGAGTCACTAACGTCAAACCGATATATGTAAAAAGAACCAATGCCAAACTCAAATTTTCTTAAACTACAGTAATCCTACAGTAATCCTGTACCCCTACAGTACTACTACAGTACCTTGGCATTGTCCCCGACCAATATACAACCCAAAAATATACCTTCAAAAACAAACACGTAACTTTTCCCAAACTACAGTAATCCTACAGTTCTCCCACAGCTGCAGTACTACTGTACCTCTTTAGAATATTTTTCTGTTTTTCGATTTTTTCAAAAAAAATTCAGTTTTTTCAAAAATTGATTTAAAAATATTTCAAGTTACTTTTTAAAAGCTTTTCAAAAGTTTTTCAATCTGTAAAAATAAAATTTTACGGATTTGTATTTTTTAAATTATCTGAAATTTTTCTCAAAAAAGAAGACTTTTTTTTTCCAGTTTTCAATTAATTTCGGTAATTTTCAAAAGTTTTAGGTTTAAAAAACAATTCAATTTTTATGTACCTTAAGATTTTATCGACATAAAAATCATTAACAACTACGATTTGTAGCGGCAAACCTTTGTTTTTGGCAGTGGAGCGTTGCGCCTCGTCTTCAAAAAGACAAAATGGTGAAATCCCAAAAATCAAATAATTGTTCCGCTACGACAAAATACCGCTAAATAGTAATTTTTCATAGTAAGTTCCTTTTCAAAAGTGGCACAGACCTGATGAAACGTGTCGTTCACCTCCTCCGAGTCCTGCCACGTGAGCTGGTGCTCCGGCATGGCTGATACATTTGTGAATTTCGCTAAAACAGAAAAATATTATCAATAAGCGGAAAATTTCGTGGTCTCAACACGACAATAAATAATAAAAAGTATTCGTGGTGAGACCCGTGTTGTTTTGGAGCAAAATTCTCAAAATTGGGGTATCACGTTGTCAGCGTCCCGTTTCGGTTTGATCAACAAAAAATGCGAAGTGATGCAGAGTTTGCTGACGGCACATTAAAAAAAATGCCCGCATTTTTTGTAGATCAAACCATAATACGACAGCCTGGCAGCGCCACGTGCGGGGATTAAAACCCGAGCCGCACAGAAAAAAGGCGGGAGTTTTTTCGCAACATCGCGGCACGGGGCGGTTTTTTGTTGACCTTTATCAATAGTCTAGATACTTGCGATTTTTGCAAATTCATACAATCAACAATAAACCGACCGTGGCGCAGGGTTGCAAACTCTCTTTTTCTGCGATGCTGATTTTTTGCGAAATTCACGAAATCAAAATTACAGCACACGTGGTGTCAGTGTCTCTCATTTCGCGGCTTGACCTATGTAGATCTAAAAAAAATGCGGGAGAAGTGACGCAGAGGTCTCAACTGATTTCGCATGGCGCCACACATTTTTGGACAATTCTCGCCGCATTTTTTGTAGAGCAAACCATAACAGCCTGGCGGGGATTAGAAACCGCGCCGCACAGAAAAAAGGCGGACCGTAGTCTAATTCGCAACACCGCGGAACGGTTTTTTACTTGCATTTCAGATTCAAAAAATCAACAAAAAACCGTGCTGCAAGGTTGCGAATTCGTGCTCCGCTCCGCATCTTTGTGCGATGCTGCTTTTTTAGCGAAATTCACGAAAAAAAAATAGAGAATAAAAGTCCATTTACCGATACAAGTGACTGCCGATAGACTTCGCCGATATACATGGAGAGAAGTGTAGAGAGTGAAATGTGAAGTTTATTAGAAAACAATTTTTTAAAATTATATGTTCATGAGGAAGATTTGCGGTAACTGGTAATCGGTTTTAATTGCCTTTTCGAGTATATGAACTATTTTAATCACTTGATGATCGCTAGTACGGCTTTGCGCTTCCCATCTCTAGATGACGGAATCCACGTGGCGATACTGATCGAGTGTTGTTTTGGAGTGGTGGTGCTGTTGGTGCTGGTGGAGGGGCGGAATTGAGGCGGTTGCAGTGGATATTACGCTGATTGGATTGGTGGAGGAAATGAGAGAAATTTGCGAGCATAAATTTTTAAAAAACGAAAGAAAATTCTTTGTTATTTGGGGAGCAAGGCGAAAACGGTGTTTTTTTGGGTCAAAAAGTAATAAAAATTTACAATTTGACAGAAAAATGCGGCACTGAAAAGCTGTTTTTAGGGTCGAAAATCAAAAAAAAAATTTTTTTTTGCTCATTATTGTGGCAGAAAATGGCGAAAATCGGTTTTTTCAAGTTACATCAAAACAATTTTTTTGCATTTTACAGAAAGATGAGGATGTTTTAAAAGTTTAAAAAATTTTTTAAAATTTTTTTAGCGAATGGAAATTTTCTGAAAAATCGTGCAAATGCCTAATTTGTGCAAAAATCTTATCTGTTCAATAATTTTTAGAAACCACCGGTTTTAGAAGGGTAAAAGGCAAAAAACTGGATTTCCAGTGAATTTTATACTAACAATGGGAAAAATTCGGAAATTTTTTAAGGAAAAATCAGAATTTGCAATTTCTACACATATAGAAATTGAGGAGAACTCCTCGGATTGTTTGCGGAGTTACGATAATTTTTTCGGCTCAAAATTAACGATTCAGAGAAACTTTAAAAAAACACAATTTCAGTGAATTTTACACGAAAAACGGAGTAAAAAGCGTTTTTAGGAATTTCCAAGTCAAATTTCCGATCCTGCGATTTCAACCCTGAAAAATAGCGAAATTGAGGAAAATCTCGGATTTTTGCAGATAAGTAATATTTTTTCCAAGTAGCTGATTTCCGTCGCCAAAACCCAGAATAATTTACCAATTCGACGGTGGTGGGAGAGCCCAGGCTCTCGTTGGGCCGTGAGATCCGAGAACCAATTGTGCCTGCAAAAATCGAGTAAACGCTAAATTGATGTTTTCCGCTATTAAAGTGCATATAGAAATACGAAAAAGCAAAAAAGAAAATTTTTTTTAACCCCTGGAATCCGAAGAGCAGTTAGCTTGCGGATTGGACGAAAAGGGCCTAAAACTTCATTTTCCTGAAATTCCTCGAAAAACCCACTATTATGGGTAGTCGGAGATGGCTGATCGCCTCGTCGCTTGTAATATTGCACGCCTGGCCACCGTAGAGAAAATAAATGTAGACTGCACACTAGGATGATGGGAAGAAACGACAATCGGCATGCGTCTGGAGTGAAGAAATCAAGATTTTTCAGAAAATTAAAGATCTCTAAAGGTGTACTACACCCTTGTTGAAATGGCTTTCAAACATGCCTATGGTTCCACCCAAATATCATGATTAAAAAATTAAAATTCTAGAGTTTGTTTGAAAATCGAAAAAATCTCGGTTTTGGGAATGCCTAATTCCTATTTGAATTAGAGAACCGCCAATGATTTGTTCGATGGAGCGCCCTTGCACGTTTTTAAATTTATTTATTTTATTTATTGTTATTTTCCGATTTTCAATTTTTTCCGTGTAGTTTTGCTTGAAAATTTTAGAGAAAAAGTTAAATAAATGCAAATTTCCGATTAAAAAATCCACTGAAAATGCGTAAAACTAATATGCTAGTTTCAGGTTTATTGTCGTCGAAAGTCATTATTTTAACAGTTTGACGTATTTTTCACGTTTTTACTTTTTAGCAAACACATTAATCTTGCTTTTACTTTCCGATAAAAATACACAACTAATGAAGAAAACAGTGACATAATAATAATAATAATAATTAAAATAATTTACACTATTACGCTCGCTGGGAGACATGAGGGAATACAGAATACATTATCATTGTTCGCTTGAACTTGGTAATTGGTGCAGGGATCGTTTCCATTCCATTATGTTGTCCTTGTACTTGCGTTGTCCTTGAGTAGACTCCCCCATAGTGGGCGGGCGATTAGTGTAAAACAACCACGGAATGAAAAAATAGAAGAAGAATAGAATATATTAATAAAAAAAATGAGGACTGCAAGCGCGCTCCAAATAAACGATCGCGTTCAATTGGCGGTAATAGTTTTCAAATAGAGGCAAAAACTTTTTCAGATTTTTTCAATTTTCAAAAAATCATATAAAATTTATAATTTTTTTTTGAAGCTTTTTAACGTGATATTTGGTCACTGTGGTACCATAGGCGTGTTTTAAAGCCCCCACGAGTCCACATTTAATAATTGAAAATTAAAAATTCTACCTAACAATATCGAAAATTCCAGAATCTCCTTGATTAAAACTTTATTATGCCTAAAGAGTCGCGTCCACACGGAGAGCGCAAGAAATCTGAAGAATATTTAGGATTTTCAAGGGAAAATCAGATATCGGTTTTTTTTAGCAAAATACCACAGAAATTGCGTATGGAATGAGTAGAAGAGCCGGGTTGACTTTCCGGGGAAAGTTTCGACGTGTGATACTCGTCTCAGAGAGCCTCATTCCCAAGAATCCGGTTGCGATGCTGAAGAAAATCGATGGAAAAAGTCTAAAATATTACCCCCTGAAACCCTACCTAAAAATCAGAAAATACGAGAAAATATTGATTAAATGAGCCGGCACATAATTGGACCAGCACTCCATTCAAGTTTCGAAACGTTTCGCCGTTTGAAGTCCAGAAGCCGGGAACGGATAGTGGCTCGAAATGCTCGTCGACACTCATTTGACTGGCCCTGTAGAGCCCGATGATGGCAATGGCGAGCATTCCCACTTCCACATGGTGTCAGGCTCTGAAAGTTAAAATTTAGCTTTTAGACGGAGAAAATCGATTACTTTAAGTGACATGAACTTGATCGAAAAGCCAGCGTTACGGGTATTTGCGGTGCAGGCCCGATTCCCGACTACTCGACACAGTATTGGAATTCGAGCGGATACTAACATCTGCCATTTTTTCTCTGAAAATTCAGAAAAAATAAGTTTTAAAACAGAGTCTTAAAAATTAACGGAAAAATTCGAAACTTTTTTTTCCGCCATTGACAATGTGCCTTTAAGGTACCGTAGCTCTTCGTGTGAGACCACTGCGCCGGGCATCTGATTTCTGGGAAATTTGTTTCGAATCCTACGTTCTTTCTTTCTTTTTGTTTCGGTCATCGTTTTTTTGTTGCTCAAAAAATCCAATTTTCAGACACAAAATGTCAGAACGCCAATCCACATTAATTTTGACTATCAAGGTATCGTCATTTCCTCCGGACGATAGATTCGGTGACGGACCTCGTTTATCCAGTTCATTTCAGCAAGCTCTGTACGTGAATTCCCTCCGATTTCATATTTAAAAGAATAAGCTCGTTTTCAGGGAAAAGCGGCCCAACAATGTACGGTGTCTCCAACGCATTTGATTTTCCAACAAACTTGGAGAGGAATCTTGATAATATCGAAGAGGGAAAAAATCTTGAGACAGTATTTATTTGATTTGGGCCCACTTTTACGATCTGTTAACTCCTGATTAGACGTCGATCCAGAATCCCGCCCTGAAGTTCGGTGAAGTCATCCTATGGAACGAATCGGACTGTGATCACGATGAGAGGATAATCCTTCATATCAAACGAGAAAAACCAATTTATGAAGCGTCTGCCAGCCAACCGTGAAATGGAGACTTAGTATGAAAGTCGGTCGCGTCATCCAGCCCACCGACCTCGTTCTGGACGCCAGTATGCACCGTCACCATGCGTATGTTTCTTCTTGATTTTCGTCTCTCTAACCATATAAGTATTTATTTCAGCAGAGACAGAGGCGACCCGAGCGGAGCCAGACGTTTGGCTATACGCCTGGATTCGATTCGAAACTACCATGAAGGTCTAGACCCTTTCAATATGACTGCAACATTCGAATCTTTTGCCAGTTGCGATCTATCCGACCCAGCACGCGTCTGTGAAGCGGTATTTCCTTTAAATTTTGTACGGGATTTTGAACAAATAACTTTCACCCGGGCATGGAACGCAGGCTCTCCTGACTCTAGGAAATTCGGAGTTTGGCGCGGATACCAAAGCCTGCTGATAGCGACGGCGAAATTGATATCGAGCAGAAAGAATGCTGGAACTTGCCAGAAGACAAATGCCGATAAGGTTGCTTTGTGGATTCTCGTAATTAGATTTTGCATCAAGATGCAGCTTGGCCTGTAGGTCGGGAACGCCTACCGACTTGCGAAAACTCTCGCAGTTCGACTTTATTATCCCACTGCAGAAGCCATTTTCACCCGAGGAATTTCACGGACAAGACCTTGATCTACCCAGCCGTCGGAGAATAATTTTCATTTCAGTGCTTTTGGTCGATGCAGCACAACGGTTTTCTGATCTATGAGCTTCAGCCTGTTCTTCTCAGACAGCATGTAACCTCTGTCAACGGAAATTTAAGTTATAATATTCATTTCTTTGTCCAGAACCTAATTTTAATTACGGCTCCTTACCCGCGTCGTTCCTGCCAGTATCACCTGAGGTCTCTTCCGTTGACAATGAGGGCACTCTAGGATTGATTGATGACCCACACCATCTTCTTTCATTCTTCGTTCATCATCTACAGCTGGTTATGTCCTTGAAGGCTATGGTAATCATGAGTGGTTCTTATTTTGAAACAAACGCTTTCAACAGGCCGAAGTTCGTGCTGTTCGAACCTCAGAAAACAAATCTGTCCGTTACCGCATTGTTCGTACATCGGGATGTCCATTTTTGAGGCCCAGGGTCCTTCGTTACTCAGGTCTCTAAAGTTAAATTAAACTCGTCCTTTGCACCCCTGAATTTTTCAGTTCGTTGTTGGTCCAGTCAAAGGAATCACTCGAATCAATGAAGACTCATTTGTGCCAAACATCCGAATGTCCTACTTCAAGATCCCCAATAACTTGAAGGAAGGAATCGCTATTGAGCGGAGGAGTTCAATTCGTTGGAAAGTGACAAGCTGGCGACAGTGAAATTATGAACACCGAATCCATGTCCAGCGTTCCTTGTAAACTCCGGTCTCTGGTGATACGGTGAGTCTTCAATTATTATAGTTTTTATTCTACGAGGAAAATATTCAGCGCTTGTTCCAAGTGTACTTGAAGCCACCAAGCGATCATGGCAGTTGGCGGAGAGTGATTCGATGGGATTGGATTTCAGCCAGATTACAGTTGGAGACTCCTTGGTAGAGGAAAGTGAGGGTGTCAGCATGATAATTGTAACTGAATTTCGAGTAAGGTTCCTGGCATGGGTGCTCCGTCCATTACTGGCTTATCAAGGATTGCCGTGGCTACCATCATGGACGTATGCTCGACAGCCATCTGTCCTCCGTTGATTGCGATGAGTATCGCCGTCGAGCAAGAGCAAGATCGGCCAGAACTACGCCAGCTGGTAGTTCCATTGAGAGCATCAATTCAAGCACATCAAGAGCATCTGCAGCTACTTCGAGGCTCAAACGTAAGTTTTTTTAAGGTTGGAAGATGATAAAAACAAGTTTTTCATCGATTCGTTGGCACTTCAAGCAGAATTCCATCTGGGTACTAAAGCTCAACATCTTCCAGGGTCTAATTAAATATATACGCATCCCGTTTTCCCCCGTGGGTTTCAAATGTTCTGCTCATTTTTAATCTACCCGTTATCCAACAAACATATGTTAATTTAAACGTCAAGTTCACCACCATCCCATTCCGCACAACTTTTCTCTCGTAATTTTCTCTTAGTGCTCAAATGAAGGAGGTAGGTTATTCTAGTGAATATACCCATGTTAAGCCGCGAATACATCCAGAAAGTCCCGGCATCAAGCCGGGAGATACTCCCGCCATAATGATAGTTGAACGGTACATCCAAGATAGGGTAGCATCGCGATAGACGTGAGCAAGTTCGTTATGCACTTGAAAAACTGAAATTTCAGAAACGAAGATTAGGTGATCGGCAGAAGGTTAAAAACAAACAAATGAAATATAGAAACGAAGACAGTGATCGACGTATTCCGAATACGAGAAGCCATTCCCGGAGATACAGTGATAAGAATCTGATCGAGAACACAATGAGCACACTACCACCGGGAACATGAATTCCATGGAAACACGGAGACAAAGGTCACAGTACTGCAAAAAATGCGAAATTTTTTTGCTTTAAAAAATGCAGCACTGCCGGGTCCCACCACGACAAATTTGTTGTCAGTTGACCAATAGAGTGTGCGCCTTTAAGGTACTGTAGTTTCAAACTTTTGGCAATAGATTTTCCACAGTTTTCCCGTGAAACAAAAGTTTGATACTACACTACTCCTTAAAGGCGCACATCTTTCCGCATTCAACTAACAAAAGGTTGTCGTGTCGAGACCCGCGGCCACTGCAATTTTCGTAGCAGAAAAAATTTGAAATTTTCAAGTCTTGAGGATAATATATAATAGTTTTACCTGAACAATGGGAATTTGCATTTACAAACTATCCAGACAATCGCTGAACCCGAAAGTATCACTAATAACGATCGAAAGTGTCGCGGAATGTCACGTATCGATTGGTAGATCATGAATATGTTGCCAAGTAACGCGAAAATCTTGAAAAGTGGGGGATTTTGCTTTTAAAAAAGCCAAAAAAAAAAACTTAAATTCGCCAATTCCCAGTTTGAATTCCCTCCAAAATGAGAACTGCAGGACCCATCAGCGATTTGAGTGGGCGGAGTCCGAGGGCGCTGATTGGTCGTGCAGTTCTTATTTTGGAGTGAATTCAGCCAAATTTGAAACATCTCGTTTGTTTTGCAATTCTTTTGTGTTATTTTCGACATGGGGTTCATTCTGGCTTTCCTCATCAATGGTGTAATGTCGTATTTAAAACGGGACAACCGGGACGTTTTTATGAAAACACTCAAAATAGAACGGGAGTTACAAACTGGGCGGTTAGAAAAAAAGATAGGGCGTAAATTTTAGTGTATTCGAGGCAAATAAAAAACTGCATGTTTCCAAGTCATTAATCTGCATGAATTGATTAAACTGACTAAACTCACAAACAGAACTTTAAAATGTGCAACTGTAAAATCATGAGGTATAGAAATTGTCCCGTTATCCCGTGATAATTTTGAGAACGCAGCGGGACGTCCCGTTCCCGTGAAAACACTCAAAAAACGGGACTACGTGACAAACGGGACTCGGGACTTGACACCCTTGGGCATTCCTCATTAAATCACGCTCCATTGATAATCGCCCTGGTCGTGTACTCCACACGGACAAATCACATTTAGTTTTACCGAACTAAAATCGAGAGAATTGGCAGAGTATTTGCCGCCTGGCCTACGCCCGGCAAAAACTTCCATGGATTCAAAATATGGGCGAAGCCAGAAATCCGTGATATTTTCAGCACATTTTTTTGCTTCGAATCTCAGTTTCTCACCACAACGAACCACTTCACATTCGGTTGCCGCCCCCTTCGAAACGTGGACTTCCAACTGCATTCACCGATTCGACACTTAGCTGGTACTGACATCATCATATTTACCAGCTCATACTCGAACTCCGGAATATACGGCACCACATAAATCGGTGAATGGCTGGTTCTGGCGGTGGCGGCTCAAATGACACTGTTCCTTGATCTAAAATTTGTTTTTTTCTAAACAATTGTCACTACCAAATCAAAAAAAAAATCTTACCAGAACTCATAATTTTTGGATTTTAATTTCGTAAATTGCAAAACAGAAACTGTATTGGAATTTTTTCGCTTTTTATTTATGGGAGGGGGAAATTCTTTGTTGTTGTCAATAAAGTAAAACAATTACAGTAAATGCCAGTACAATAGATTTTCACGTGTAATATATTAACCAATTACTATATTTTCAATAACTCTGTCCTCTAAATAGGTAGTTGGGGGGAAGGTGAGGGAAAATGGAAATAATGAAGTGAACTGTTTTGCGTACTTGCGATAAAAAAATCAATAAATGGGAACAAGCCGATGATAAACTGATAAACGTGAATATCGAGAGAGGGAGGAAGAAAGCACGTATACCCGTTAATGAAATCAAGTTAATGGAATTATTTGGTTTGTGAAACAAAACAACGAAAATGAATATCAATGTTTGAGCATAAGGAATGAGGGAATGGCACTCTGGTGGTGGTGGATAAATGAATCGGGGGGAACGGAATCTATGGAAGTCTAGAATACATCGCATCGAGTTTTCGGGTGAGTAGTGATCCTTCAGGTTCGCCAGACGCTTGCTCTTTCCACGTTCGCGTGAGAAGATCATTCTCGACGCCGAATTGCTCGGAGAGACTGATATCGCGCACTTGCTGGAAAGACAAGAGCCGGCTTCTTGCCAACAACCATGTCATCGAGGATCGCCTTTCGAGTTGGTCGTTGTTGCACGAAAGCTCTTCGAATGATCCCTTGATTCCTTGGTCGGCGCAACATCGCTGGGACGAGCACCTAAGGGAATTGAAAATTACATATATATATATATATATACACTCCTCAACGCCGAATAAATATTAGAGCGCGCTTACTGAGCTTCGCGTTCATCCGCGGCATTTTTGACTTTACACTGAAAAAAGCAGATATTTCAGATTTATCGAATTTTTAGCTTTGTTACAATTTTTTTCATTTTTCGAACACTTTTGTTAAACAGTGAAAACTGAATTAAAATGACTAAAATGAACTTTTTTCGTTCACTGGTTAAGGTGAAATGGTTGGAATTTGAAGAAATCAAAGGGATTTTTCTGAATTTTGTAATAATTTTCTATTAAAAATCGGTTTTAAACCATTTTTTGACCCTAATGTCACAAATGTAGAAACCGGTTTTTAACGGAATAGAAAATCTTTAGAAAATCACAAAAATCCCCGTTGATTTCTTCAAATTCAAACCAGTTCACAACCAGTGGACGAAAAAAGTTCATTTTAATTGTCATCAAATTCGATTTTCAGAGTTTAACAAAACGTTTGAAAAATGCAGAAAGAAAATTTTAAAAGCTAAAAAATCGATAAGAAAATATGCTCTTTTGAGCTGGAAAGTCAAAAGACCGAAGATGCAGAAATGCGAGGCGCAGCAGAGGATCGCGCTCTAATAATCGGCTTTCGAGGAGAGCGTGATATAATATATTTTTTTTGAGAAATTTTGCAAGTATGTTAAAACGAAAAAACCAACCTCAGCATCAGGTACAACAATAGCAATAAGACGTCTTCAGGCTCATTCTTCATCAACAGATGATTGAGCGACATATTTCGAGCGGACATACATTTTCTCAATCTTCCCGGTGCCACGTATCCTCCTTGCGAGAGCTTGAAAATTCTTGCGATCCAAAATTTTCAGCGTTCCCTCAGGAGTCCATCGTCCAATGTCTCCAGTATGCAACATCCTCCTCGATCGTCTCCTTCGTCTGTTGCTCTTATAGTATCCCTTGAAGACGATGTGTTCCTTGCGAACAGACACCTCGCCGGCTTGATCCTTCGCGTAATAGTTCAACTCGGGCACGTCGACCAGCTTGATCTGACACGATGGGATTACCATTCCGACGTGTCCGGCTAGCGAACTCTCCTTTCATCGAGACAGTCCAAGCGGCGACACATTCCGGTTGACCGTAACCGTCGACGGCGACCCATCCCATACGAGCGGCACGAACGAAGGTGAGCACATGCGTCGAAAGTGCGATCGTGATCATCAGACGCACACGCCCTCCGAATCCATCGCCAATCTTTTCGAATACCAAATTGTCGAAGAATCGGCCCCGTCTTTTCTGATATTGAAGCTGGAAAAAAAAAGAAGATATTAAATACTATCAAATCATTCAGATCTCTCATGATGCCATATAGTCTCTGGCCTTGTATGAGATAGCGAACTCAAACAACATCTTCTTCAAAGTACTTCACTTCCGACATCACTGATTATCGTAAAGCCGATTAAAGACACGAGAAATCGGGCACCATTGGCACAGTCGGCCTCAACTCTTTGATATCCTCGGCCAACACACGTATGTGGTCACCGCGTTGGAATCCGACTTTCGCGCCGACACAGAAGCACACACTCTCGATGACTCTCTCGGAGCGTCATGTGAGCCAACGGAAGGAAGCTGATCATCGAATCGGTCGCATGCCACTGTGCTTGTAGAAGTCCATACACACACGTCGGCGATCACGTTCGCGTGAGTGAGCATCACATTTCGGTGTTCCAGTCGTTCCTGACGTGAAGCATATGGTCGCAAGATCCTCTGGTGACGTTTGGTGGACTGTGTGCTGAACGAGTCTTGCGTTCTTTCCTGTCTCGAGATCAAGTGAGCACCTCGACTCCGAGACGATGACGCAGTCGTTTTGAGCTCCTCGGTGACTGGTTCCATCAAGCGTGCTCAAACTTGGGCATTGCTCCTTGAACTTTAAGAGACCTGAAATCAAATTTCCTTTTGGTTTTAATTTCCTTATCTAAACTCACCAGTGGCCTTTGAAATATCATCACAGACAACTTTCGAATCTTGATCTCTGCCTGATTCAAAATGAATATCCAACCGCTTCTATGATCCAAGGGTCTCGTAGATCGGCACAGTCTCATTCGAATAGTTGTAGGTGATTCGGTGATGATCCATTCGGCGCAGAGTTGCTTCGATTAGATCCCAATGTTCTCCGCCGTTGCCAGTCGGAACGCCGGAGCTCACGGAACGCGACGGACACTTTGTCGGCTGGCTCAGAATCGTATTGTACGACTCCCACACGTACGAGATTGAACCATCCGACTGTTATGACTCGACGTCCGAACATCGGCCCGGTTCGAGAAAGGGGCTCCACGGCGAACGACCACCCTGGTAGAGGGTGCGCGCGTCTTCGAACAGGAAGCCTCGTCAGTTCGTCGTCCTTCAGGTGGCGCTGATGCGGGTACCATCCTGGAAATTAACATTCTAGTCGGGGGGTTTTTGTAATTTTTTTTTCGCTCTTTTTCTATTGTAAACCGAGCCACGACGCGACACGCCGTAAATCTACAAGCCCAAGTGGCCTAATTCGGCAAAATCTTACATTTAAAAATATGGGAGGGAAGACAGAACTCCATGATTTGAGAATAAAGGAGGTAACGGTTCGGGCGACGCCATTTTGAACGCTCAGTATCGACATGAGCTCAACAAATGAGATCGTAATGAAACTGGTCAAAAATTTTTATGGCGGTTCAAAATGTTGAAAAACCTAAGTACACTGATTTTTATCCGGCTAAAATCACGAATTTTCCCATTTTTCCGTGTCACATCTGTTCGAAGTTGGATTATTTTCTTGGAATTATCGTTTTTTATTACTATTTTAAATTGGTAGTTTATCTCATTTAATGTCGTCGATTAAGTACTTTTAAAGCCGATAGATAACCAATTTCGATATTTCGGGTCACCTATCGGCTTTGATAAAAGTACTATAAGACAAAATTAAATTAATTACCAATATAAGTAATAAAGGACATTTCAAAAAATCCAATTTCGAACAGATGTGACACGGAAACAAAATGAGAAAAATTCGTGATTTTCACCAAAAACAGTGTAATTTGTGCAAAATTTCTGTGAACCGACATAAAAAATTTTTGAAAATTTGTGGATTTGAGCAGCTTCATTACGAAATTCGTTCATTTGAGCTCATTTTTGGTCTATACGTTCGAAATTGGAACGTCCGAGCCGTTGGTCCTCCTCTCTTTAAGTTTAAAAAAAAAAAGACGGCATTATTTTGCCCAGTTTCTCTCCAAAACTCACCGGCAAAATGCGACTCTGATTCATAGGATCCGTGGCTGACATTTCCCGAATAGGTGACCCCTCTGAACGAGTAGGATCCCGACGGTCGATGACGAGCTACAAGTAGTATCCGAGGCCCTTGGTGACTGCGGCGGCGGCTCCGATATTTGAACGTCCGGTGGAAGGGAAGAGTTCGAGCTTGGTGCCGAAATGAAATCGACAATACTTCTGGAACTATTAAATTATATATAGAGAGGACGGGTGATGATGAGTCATCCAGGTTGTTGTTGTCGCGCTGTGCGCACGCCCGCACTGATCCCCACAAAACAAGACAACTTATTTGAAGTTACGAAATCGAAGTTTCTTTGTTATTTTATTTTTCAAGATGGTTTTGGTTTATATACCATGTAAAAAATACCTAGGGGTTTTTTGCGCGTTTGGACTCAAGTAGAAATGTTGAGCCTTTTCTGAAAAGTTTAATCCGATCAAAATTTTGGAAAAAGGTGAATTTTAGCGACGCCGTGGTTTTTCGAAATATTGATCTGCCATTAAAGCCCGTGGTGTAGTCAAATTTTTTTATTGCTTTAATTAGCGACGACTCAAAATTGTCCTTCTGTAAAGAAAACACAATTACCCTTCATAAAAAAACTTAAATGTAAAATTATCTAAAGTTTGAAATTTGACCGTGGTCAAGCGGCTGGAAACGTTTTTTTAATAATCGTCAAATAATATACAGTGCAATGATCTCATTGCGTTTTCAACTTTATTTAACTTTAAAGTCATGAACGGCGAGATTTGTTTTTAATTTTTCACCTAGAAATCTCGCCGTCCATCGGCTGTAAAATACCTAAATGAAGTTGAAAACGCAAGATAATTGCACAATATACTCAAAATTTGACGTGTTTTCAAAAAAAAAAATACTGTTTCCACCGTAGCGGCGACGTCGGTCAAATTTCAATTTTAACTGAATTTAGGCCATTCGCTTTGTCATAACTTGTTTTGAGGAGTTTTCAAGAAGTTTCATTATGAAATTCGGTGTTTTCAGACAATTTTGAGTCTAACTATAAAAGAATCGACTACACCACAATGTCAGATCAAAGTTAATTTCGAAAAAACTCGCGAATTTTCGCTAAAATTCACTTTTTTTCCGATCGGTAATTTTGATCTGCCATTAAACTTTTCGGAGAATCTCAAACATTTTGAGGATAAACGAGCAAAAACTAGTCATTGTTTGAGTTGCCAATGGTATATAAAACATGAAGACCATCCTGTGAAAAAAAAACAACAAAAACACTTGAAATTCGCAATTTCATAAGTTCTCCAAAAGGGAAAACATACACACACCTCGATTGAGACTGTACCCACGCAGCCGAGTCTGTGATAACCATTTTCTGGTGTTTCTGTGTTTACGTGGTTAATAGTCTTCTGACAAAAGAAGACATGAAACCGCTTCTAAAATGAGATTAAATTGAGGAAACGACGACGACGCAATAAGAGGTGCAAGGAGTGAGGGTGAAAATCGAAAAACAAAGAAGAGATCAACGTTATTCCATCTTTAGAACTTTCTTCACTGCCAGCAATTGTTAATAATAATAAGGTTTTTAGGTCGATAACTCTTTCGGTGATCAATACAAAAAGGGGTGAAAACCCGCCTCGACAAGCCTTTCGATCAGGCCAATTTCTTTATCACACTCTCCGCAGATTTAGGAACAAATTTCACCTCCCCGGCAAGGGGGCAAAAGTTTCGAGAAGTTGTGTTGCGCGCGAAGGGGATGGAGAAGATGGAGAAGATAGGCAAACACGTACACCTACTCAAACAAGTAGTAGTGATAATTGATTTGATTAGTGATTCGGGTGGGCAAAAGGAGCGAGAGAGAAAGTGAGAAAAAGCGAAGAGGGAACACGTGTAATCAACAGTGTGCCGTTCACGCCCTTTGGACTAATGCAGTTTTTTTGGTGGAAATTCAATTAACACTGAAAACTAGTTTTTAAGTGTTTACGCTGTAACGGGCCAGGTTTATGAGGCAAAACGATTGAAGAACTTTAAATGTGGGGTCCGAAATCTGAAAAATATTTTAAATTGACTCCAAAATTTCCCCTGACTCCGAAGATGCGAAAAAATTCAAAAAAAATTTTCCTGACTTTATATTTAAGCCTGAAATCGCCGAATTTCATTTAGAAATTCGCATTGGGGACAAGCGCACTTGCATGGTTCGATTTTTTTTCGTTTAGTTTATTTATTTTCGCCGAATTCAATGTTTTTGAAGCCATCATTGACCATTTTTGTCGAGTTCTCATGGAAAATTTTTTTGAGAGAAATTACATGAAACTGACTAAAAAATTAAATTCGGCGAAAATAAGTAAAATAAACGAAAATCTTCGCAAACTTGGATGCAAGCGCGCTCCAATGAGAGATTTCTTTGGGCGCTAGGTTGAAAAAATGGGGGCACGAATGAAATGTCGGCGATTTCAAGCTTATATATAAAATCAGGGAAATTTTTGAATTCTTTCGCGATATTCCGAACCAGGGAAAAATTTGAAATCAATTAAATATTTGGTTCAGGTTTCGGTACCCCGCCTTTAAAGGATTTTTTGGCTTAAAATTGGAAACTCTTGGTTAAAACTTGTAGAAGAGTAAAACTGTACACGTTTTAGACGATTCAAAAGTATCCAGGGAAGTATGCAGAAGTTGAAAAATTGCGAAAAACAAATAAGGCATTTTCTCAACGCGTGAATGCTTAGACTGAAAATAGTGTATTTCTTCCAATATATACGAAAATACGACTCGCACTGGTTTTCGATCGATATTTATAGGTGGAGTTGCTATGCATAACATTCCGGAAAAACACGAGATTTGAGGAATTTGAGCAACTGTAAAGCCAACAAAACATTTTGTACAATTTTCTTGTTGGTCTTCCTCAGAAAATTATCAATCAAAAACCAACTGACGCAGAAATCGATATATTCTGCTAGTTTTAAAAAAACACATGATTTTTAATCAAAAATTGTTAAAGTCATGCAATTTTCCTTCAATAGTTTTATACGAACTATTTTTTCTCTGGAATTCACATGCTTTAAAGCAAACGGCCGTTTCTCAAGCGGTTGTTGGCTTCCACGCGATGCCATAGAAACACTGGGGCACCAGAGAAACCGGGGTCGAAGCAAATGACCAAAACAACAGACGTATGTGAGCTTTCGTTTTCGTCTTCTCGAGGAACCACCACGCTGGGACTACAACTACGATTGATAACGAAAAAAAAATAGAAGAGATGATGATAGTTTTTGTAGCAATAAAAAGAGTGACAACAAGATACACTGTATCTCACCCACACCTTGCCGTACTTCTAACGCAGATAAGGAAACCTAGTAAGATTCGGGGGGTTCAAAGTGTTGGAGCCAAAAACGGAAGCCTTAACGGAGGGAGCAATTGTTCGTTGAACGAAGAATAAAAAACCATCATCTGCGTCTCAAAAATCACGAGATGTAAGTGAGCGGGTGGGTGAGTGAAAGTGCCGGGGAGTAAAACAAGTTATAAGACACAACGAGCGACGTTTGGCCGCTGCTGCGTTTCCTCACTCTCTCCTAGTGGGCGTGTGGGCACACTCACATGGAGCGCATGCAAGGGTGTATGCGCAAGTGGTACATCGACTCGGTATGAGAACAGAGCACAGTAGGAAGGAGCTCACGTGTTGCTCCACTACTCAGTGTTGCGTACCGTCTACCCATCTGTGGGCCACCGCGGTGCAAAGTACCGCACAGTGGAAGGAGGAGAGTTGAAAAATTGGTTTTTACATCTAGAACCTCGTTTTCCTCGGGATTTTGAAGAGAATTGGTTGACTTCTTGAATTTTAGTCGCGAAAAGCGCGGGAAAAGTCTAAAAAAGATGCGACGAGTGAATTTTAGGGCAAAAATGAACCGACACAAATTGCTTATGAGCAATCGGCTTCTCGATCGGAAAACATATCACAGAAAAATCGGAAAATCAGCAAAATTCGAAAATTATGCAATTTTCTAGAATTCCAAGCGAAATTTTCTAGAATTTGAGGCAAAATGATACGGAAACCAACGGGAAATCCAGAAGATAAAAAAATCTATCGTCGAATTCTAGGTAAAAAGCTCTGTGAATTACTCGATTCTCCGTCTCATGGGGTAGACTCAAAAATTATGCAATTTTACCTTTCTAGGCGAGACATCGCAGGATCGCCTACACAATTTCCGGAGAACGATGAATATCGGCAAATCTGAAGTAGGAGAAGGAAGAGGCTTCGGATCAGTTTTTCTGAAGAAAATACAAAACCTTCGCTTTCGCAAAACTTTCGGGAAAATTCTCAGAAAAGGCGCTAAATCAAAAGCTCAAAAAATCGACGTACGATTTGCGACGGAAAAAGCTATCGAGTAAAATATCCGAATTTCTGTTTAAAACTGGAAATTGCCCAAAAATCCGTTTGTTTTCGCCAAATTTCTCCTATTTGGCGGTCACAAGGCGAGCGGGAGCCGCCCGAGATGAAGAGCTCCACAGAGCCCCTGTGCCAACAACACACCGGTACACTCACCCAAACATATTGGAATTCTCCTGAAGGAAAACGTCAAGGGTACGACGACCGCGGCGGCGACGGTGCCATTTTTCATGGGGAAAAGAACCTTGATCGAATTTGTGATTTATTATAATCGAATTTCGCTTCTATGCCACCCCAATTACGTGACCCACCTGATTAGGTGCGCGAGTATTTCAGTGCGGTCGGCCGATCCCCCGAAAAATGGAGAAGTTGTCTGAAAAATGCGAAAATTCTATAAAACGACGGAAAAAGAAATGAAAACAAATAAAATGAGGCCGAAAAGGTGAATTAGTTTATGCAATTTTAGAAATGTGAAATTGTGGCGAGATCGAAAAAAATGCGAAAAACACGAAAACAGGTCGAAATTTCGCAAATTTTGAACGACGACTAAAATTCAAATGCACAACGTTCGCGCGTTCTCGCGCCGAAGTACGGTCGGTGAAGCCCGCATTTTTGCGCGCGCGAAATTCAAATTTTAATTTTTAATATTTTTTCTTTCTTCTTTTCTTTGATTTTTTAAGAATTGCAAAACGTTCAATTCGTTCATTTTTCGAATAAAATTGTTAAAAAAGACGAAAAAAAAAAGAAAAAATAAGACAAGTTATCGGTGCAAATAAATGCAAGTTATTGTTCGGGAAAAAAATCACAATTTTAAGTGCAAACAGATTTGTAATAAGATCAATCATTCTTTTATTTTCTTCCAAATCCCGACATGGTTTTGGGCAGCCGATCATGCAGCAGCGACCTCCACTCCCCCGAGACACGCCAACGACTCGCCGGTTGAGATGGCGAGAGGCACGAACCAAACGACCATGACCTGGAAGAAAGTGTGTGAATGTTAAGGTCTCTGAATATTCCAATAAAATTAATTGGTTTTTTTTTACCGGTGTTCTTGCCAGAAAAGCGCAAAAATTAATTAAAACTCTAATCGTGGCGAGACCCATCTTCTGAGAAACGAGGTAGGTATGCGCCTTTAAAATTGGGCTACCGTAATCGAATATTTGCATGCAATTGTTCTGATTTCCGAAGAGCGAACAAGAAAATTTGATAGAAATGACACATGAATTAGGTCATAAAATTTGCTTTTTTTTTAGATTCATATAATTCAGATCTCTATTTTGGACACGGAGTTCCATGACCTTCCTCATTGAATTTTTCGCGCTACATTGACAATGGCCTGCCGGAAACAACGTGGGAAAGTTGTGTCCTCCATGCACGGACAAATACATTTAGTATAACAACAAAAATCGAGACGCGACGCGACACGCAACGCGCCGTAAACCTACCACAGATATGGCCGAGCCCATAATGGCCTAGTTCGGCAAACTCTTCCATTACAATTGATCGATGTCAGAGTGTCACATTTCAGCTTGATCTACCTAGATCTACAAAAGCGGGAATCATACGTAGAGTTCTCAACTGCTTTCGCATGTTAAGTACGCTGACGTCACAATTTTTTGGCTAAAAATTCCCGATTTTTTTGTAGATCAAAAAACTGTGATGGGACAACCTGACACCACGTGATTTATGAAAAGCCGGAGAAATGTCATTTGGCGAGCACAAAAAATACGAAATTCGGCCACTGATTCGCGGCCACGAGCCAATGTGCCTTCACAAGACATTGCACAGTTAATAGGGTGATACCCACAAAGGTAAAGGCGCATGCTGAGCATGACTGGCCAATCTAATAGCATCTACATTGATAATTGAAAAAAGAACACACAATTCTGTTTGGCAACGTTTAGCGACGAGTGACATAATTCTCGGAAAGCTTCAGCTGAACAATTTGAGGGATTACTTAACTTCCTGTTTCCCATCGCTTCACCGTCTTAGATAGTGCCATTGCCGATTGGCAAAATGGGATCTGCCCCCAACTGCCAGTTGAATAGGATTGTCTCTCTGCGTCTATCGGTTCTCCAAGATCTTGCGGCGGTGAAGCCGTGTGTGTGGGAGTGTGGCTCCTTCATGCTAAAATGTGTAACACTGCGGGCAACGCATCCGATTGGTCGTGTTTGGCAGCGCACGGCGGGAAAACGAATCCGGATATACTACATACACAAACACACACTCACACACACCGAAGGAACGTTTCCGAGACACCTGAACTGGAGGACTTTTTATGATTTAAGTGTTTCTGCTGCCAGCAGGATGTGTGTGTGTTGTCAATAGGATATGCTATTTTAGTCCACATTAAAGTGATGAAACATCAAACCGGGTAACTTAGTCCACCCAACACTCTGTGAGCGATTAACCCTTTAAGAGTGCACTTGCACTTCTAGGCAGGATTCAATAGAATTGGGGCCTTGGAGCCTAGTCGACTTGCGATGTGAGAGGCAAGGTTGGCAGAGCTAGGATAAGCTTCTGTAAATGTAGGTCTGTAACAAGCAAGGATCTCGCTCTGGTACTGTAGCGAAATTTGAGATCAAATTAGGTTTTTCAATATTTCCAGTAACTGGCACTGTTTCCGGCCCAGATCTTAGAAAGAAAAGAAAAAAAGTATGTTAACCAAGGCGTGGGCGGCAAACGATTCCGGCAAATCGGCAAATCACTAAGTGAATTTAAAATTTCCGGGAAATCGAACTGACACTTTACGCCAATCTGCCGAACGATTAGCAATTGCCGCCCACACCTGATGGATACGTATATATGCTTTCACTCTTGTGGTGGCAGATGTATCACTGCGGTTTAATGAAAAATGTGGGAATATTTTTACAAACTTGCGGCGTCAGCACACCGCTCCAAACCACGCAAAATCAGATGAGATGTATGCGTCTCTTCCCGCAGATTTTTCGAGGATCACAGCAGAACTTTCTAACTCCACCTGTCTACTGAGAAAAGAGCCAAGAAAGCATATTTTCCTCGTATCAGGGATCGGAATCCCACGGCTAGCTAGTTGATCCTATTGCATCATTGAAGCATCTGATTCTCCACTTTGTTCGCTTTAAATCGTTTCAAACTGAAAGCGCTCTCAAGGCCGTCTTCCTCCGATTTTCCGATCATCCTACCTTTTGTTGATCAACACGTGCCCGGCGATCACAACACTGTTCAACCGGAATATCGTGTGAAGATGTTCCACCAAATGGATCGTTCGCTTTTTGGCTCAGGACGGAAGAATGTGTTACTAATTTCCATAAAGTCTGTTCTGTTCTAAAAGTTATGAATCTTCTGAAAAAATTTCAATCAGACTTAGATCCTGTCAATACATTCATGGGGAAAGCAGTGGAGTCGAAGATTTTTTATCAAAATATATGGCTACGTAGTCAGGGAGAGACTGGCTCCTTTGTTACAATATATTAGGTTTTGTTCCTTAAAATGTTCAAATGAAGCTGAAGATTGGCTAAAAGTATATGATTTTTCAATGATTTTTCAAAAATTTCAAGGTATAAATCTACGGAAACTAGTCAAATTTAAAAAAGAAACTAAATTCGATTTTGTTTGTTAGTTTGTTAACAGACAGAGCAGTTATTTTGATAATTGTAACCTGAACTCTATTTGTCTAGTTGACATCGTGAAGTAAGAATGTTTTAATGTGGCATTTATTGAAATTTAATTGTAATAGAATATTTTATTATCTAAAAAAATAGAATTGGATTATAATGTTAATTATTTTACTGTGGAAAAGATCAGTATTTTGTGATAGTTTTAACCTAAAGACATTTCTGAAGATCGTTTTTTGTGAGAAAAAATTATTATAATATGTGTCATTTAAAGCAAATTTTAAAAAAGTGCGGTCTAGAAATGTTCAACTATCAAAAAAAAGTACATTGGATTTTGGTGCCAGTCAATTTATCAACAGAAAAAGTTGAGGGTCCTAAAATAATTTCCAAACTTATTAATGCACGTGAGCATGAAAGCTAAACACTTTTTTGGGATTTTTTGCGCAAATGAATAGTGTATTTACAGAGACAATGGTAGATCAACTTAAAAGAACAAGAAATTTGCAATTTTTCCAGGTAGGACACTTTTTACTCGAATATAACTAACCTAAAATAATTTCCAAAAGTTTCAATGGTGGTAGCACAAAAAAAAACAATTTTTTTGATTTTTGAAATGAATGTAGTTACAAAGACGGTGGTACATTGACCCAACAAAAGTAACGAAATTTACTACTTTTGTCAGGTAGGAAACTTTTTTGCTACTCGAATATAACTAACCTAAAATAATTTCCAAACGTTTTTGTTGGTAGAATGTAAAATAACTTGTTCTTTTTTGGTTTTTTGAATAGTGTAGTTACAGAGACAATGGTACATTGGCCTGAACAAAAAATTTAGTTAGCTATTTCTCCATTTTGACCTATTGGTCCCCTACAAATTAGTAAAAGGACCCACAATCCAGTTATTTTTGTCGGTGTTTAAGCAGACTACAACCTTCGAATTATTTTCAGAACCAGATGTAAAGATTTTAGTTCGGTGCTGCAAAAACCATCAAAAAATACCAAATTTTTCGGCCTTTGTGAAGCACGGCAACGAGCAATTTTTGAGATCGTCTTTGCCAGCTGCACACCCCAGGTACAGAGACTCACTTTTATATCACGTGAACGAACAAAAAATTTGCAATTTTCTCACGTAGGCCACTTATTTACAGCTCTAATTTCACACACCTAAAATACAAATGTTCATCCTACCCATATATGTAGTAAGAATATTTCAAATTCAAATTTTCATGTACAAATCAACTCGTCGCCACCGTCTTATTGTTTCCCTGGATTTCCTGATCTGACCTTGTCACTCCACGTATGTTTGTCTTTGTGCCCACCTCTCGTGCTCACCTTGTTCCAAATTCTACCGTGAAAACTCATCTGAACGCCATTTTCGTATGTCCTATGAGTTTTTCGGATGCGAAACTTGGAAAAACGTCAGACAACTGCAAATGACCTCCCGGGCGTCGCTGAGAATCGGTGATAGCCTTGTACTGCTTAGATGAGACCAGATACAAAGTGCACAACAAAAAACAAATTCGCTTGAGAAGCGCTGGCGAGAGATTCGAAGCGAAAACGAGTTGATTGACAATCCGGAACATATAGACACACCAGAAGACAAAGTGGGGGAAGAAAGGAAACAAAAAAGATAGAGAGGAAGGAGATTTTGAAAAACGCCAATCTCTCTGTGTGTGGGCACTGGGTGACAGGTGAAAAAGTGAGAGTGAGAAAAACGTGGTGGGTACTGTATTGATGAACGATCCAAGTTGCATACTCAAATCTCGTTGATTGGCTTGTGTCCTGGTCGGTTTGATAGAAGGTGAAGTTGGATTTTGTTCACTGAATTATTGGATTTCGAGACATGAGCAAGCTAGGGTCAGGATGACTGTAGTGGCCGGCTAACATTCCGTACACCCTTTGGCCGACTGGTGCGTGCAACCAGGGCTAGTAAGGAGGTACATCCTGACCGTAAGCTTTTTAAAATTCTGAGAACACCCTACAAAAGATATTTGTAAAGTTCTCCAAGACAGGTGCTAAAACTTCTGGAAAGAGTAGCTTAGAGTCAGAATGTATTATTGCGATCTGATCTACAAAAAACGCGGGAGTTGAGACGCAGTATTAAGTCTATCTCATTTCGCATGTTTAAGGTAGCGTGCTGAACAATTTTTAACAAATATTTCCCGCATTGTTTGTAGATCAAACTGTAATGAGACAGCCTGGCACCACGTGGGTAGGTGTCGGGATGCACGTGGTGTCGGAGTGTCTCATTTCAGCTTGATCTACTAGATCAACAATCAGAAAACAATGCGGGAGACGAGACGCAGAGTTCTCAACTGATTGTGCATAGGTAAGCTCGCGCTGACGTCACATTTTTCTAGCAAAAAATTCCTTTTTGTAGATCAAACTGTAATGGGACCCCATGGCACCGTGGGGATGCATTAGTGATGTAGATAAACCTTGAACAATAAATATACATTAATTTCGTCATGCTTGAAACTTGGACCCAAAAACAACTATCTGTAACTAGAAATTCTACAAACAATGAGTTTGCGACTTAAAGCTGGAAGTATAAAAGTTGCGCAAAAAGAGACCTGTGGTCGGGCGCTACCACCATAAAATTTTAAATTTGCCGGTCCCCACACCTCGACATCAAACGTGCAAGCCGGGCAACTTGGTACATCTAGTTCACCAGCACTCCAACTAGCTTCCCAGAACGCTAAAAACATTGTTAAATTATTACTTGTTCAGTACATTTGTCGACTCGACACACCATCACCCCACCTAAACCCAATAAGGAAGTCGATATCTACTCATTTTAGGGACCTTTTTTGCCGCTTTTTATTGATTTGAACAAAAACTCAGCAGAGAAGTCAAAAATTGCCAATATCCAATTTTTCAGTTCCCAAAGATTGTGAGTTTCAATACCTACTAAATCCTCCCGTTCCGCCGTTCTTGATATTATCTCCATAAATGTCCGCTTATCTCCTCTCTTGTACTAAACTAACGTTCACTTATCCACATAATAAATACAATAAATGTATAATATACAAGAATAAATACTACACTATATATAATATATATATATATATATATATATATATAAGTATATAATATATATATGTATATCTATCAAAAAATCAAACAGGATCTCTATTTTCCTCCAGGAGAAAAAGACGATGTCAGGTTGTGCGCAACAATACTCTCACTCTCAATACCGCGACGACGTGGCATACCTCCCCCCATCCTGCCTTTCTTCCCCGTTTCTCCTGATCGAAATTTCCAGCAGCACACCGGAACTTCTTGGTTGGCATGTGAAGCCGACGTGGATCGTGACGGTGATGATGTGGCGGATTGTGATATGGCGGAATCGTGTTTTTTATCCGGCGAGTACTGCGAGAATTGTCTGAAAGAGTGGCACGGCGCCTGTGTTTCGGCTCTTTTCAGCATTTTGACGTGAATTTCATCCCCAAATTTCTTTTCTCATCTATCAATTTGAAAATAAATCAAAGAAATACAAAAGCTAAAGTTCACTCATGTTTTAGCACACGGCGCGAGAGGCGGAAATCGCCTTAAGGTCAGGCACAGAGCAGGCGTGTAATGCCTACATGGAAGCCTAGACTTCTCTGAAACTGGGTAATGTTGTTCCGAAGTGCAGTGCCTGAAATTATACAATGTTGTTCTAATTTTTCGGTGTATATCAAGCGCTTATATCCGTGTGTCCATAGTTGGTAGTCTATGTAGTCTCAAGTTTTGGCTTCTGGTAGGATAGTGAGTTGGGGTCAGTGTAGGGATATGGTCGGCGAAATGTAGTGGTACAATAGCGGTACGGTAGCAGTACTGTAAGATTATGGGACTCTCAGAAAAAAAAGTTTGCCACAGAAGTCGAGGTCCGTGCCGGAGGAGAACGGCTGGTTATCAATAAAGAATACCGACACTTTATGATATCACCGGTAAGCGCTAGACAATAAAAATTCGCATTCTGAGAAGGACGACTGTAGCAGTTTAGCGTGTGTCCGAGTAGATCTGGCGTCTCTTAATTTAAGTTGTAGTTTCCTGGTGTCCCCTGATCGCGAACTTCCCGAGGTAATTAGTAAATATTTTAGTGTGGCCTATGTTTACTGGTTTTACGGACTAGCCCGAGAAAAACTCTGGAACGAAAAAACCCAAATGGGGGCTCTTATCCAAGACTACCAAAGTTTCTATTCTATGCAATTCCCTAGTTTTGCATTTCCTCCGCCTAATAACGCATGTTGTTTACCGTCGACTATCCCAATGCTAAAATTTCGGAATCATGTGAAAATTTACCTGATCGAAAGTATACGGTAACCGTAACATTTGGAAGAGGAGAAAGGAATTCGTTGCAGCCTTGGCCCATTCTCCCCACAGGCATAATTCAAAAAAATATTTATCGCAGCAAGAGTGTGGATTTGCCACAACCCAGCGGGTTCTCCCATCCAGCATCTCTACCTTTGCGGAGGCAGACACTGAGGACCTTGATCTGCCGCCGCGTTCCGACAAATGTAATAGCAGCCCCCCGCGCGATAGCTTTTCACTATTTCTTCTCTTTCTGGCTACTGTGCTGCCTCCTCCTGCGCAAGGATGATGCTGCTAGGATGATACCCTAGAGATGACGGAACGATCCGATAATTATATTATTGATGGAGACTAGAGATGTGAGATAGTCCCGCAGCGAAGGAACCTGATCTTGTTACAGTCTTGGAACCCAGGAACAGCGGATAGCGTCGTCGTATTATCGTTATTCATTTCGTAAATAGATTTTCTCTAGGATTGATTCCCGGTTGAGCTACGTCACTGTCCGAGAACATTCCGGAATGTTATGTGCAGATGTTCTTTTAAATAACCTTTCTCCTTCCTCCCGCAACAACTTTCATTTCTATGCGTCGAGATACGATATCCAAGGCCACAATCAGTATCTTTTTTCGCTGCTGACTCTCTCTCTCTCTACTCGTAACCTTCGCCCATCTCGTCAATGGTTCAGAATCACCTACCGCAAAACAATTGAAAATAAGTGAGTGTGGAAGTCACGTCATGAGCGCCCAATAGATAGAAAGAGAGAGAGAGAGAGAAGTGCCGAAGACAGTGTCGGAATAGAAAAGTGGAACCAGCGGCTGGATCGTCATTTGTTGATGATTCCTCGTGCCTGCCATTGTTATTCGATATTCCGATATTCGATTCTTTATTGCCGCCCCCGCCTAAGAGCCCGTGAGAATCAGAACGAAGCTTGCGCGCTCCCTATTAAAAAAAAAAGATTATCAAATTTGAGCAGAAGCGGAAATGGAAATAATAGCGGATAACGTTACAAAAAGAGCGAAATGTTTTGGGCAATAAATTTGTAGTTTGATGATAAGAGTGGCATTTTGATATGAGGAAGCTTGCAGAATGTAGTGGTGAACAGGAAGCTTTCGCTATGGAGCAAAATGGATTCCGTCATTTTTAACTTAAAGAATCGGAGTCGAGATGAAACACCCAGCCGGGCTGAAAAATTATTCTGCTATCGAGGCATGCTTGAAAGTACCAGGGCCTTACACAAAAGATCAGGGATCCTAGTTCTGCAAAAAAAATTTCTGCATAATGAAATGGAGAACAGGGCGGTGCGGCAACCAAGAGTTTCGGCAACTTCGGCATTTGCCGAAGTTGCGGAACCCACAACATTTTGGTAACCGGCAATTGCTCTCGAAGTTGCCGAATTCAAAAAAGTTCGGCAACCGGCATTTCCGCGGGCGAAATCTCCAAATTCAAAAAATTTCGGTAACCGGTTGCCTCACAGCTCGGCTGGAGAAGCCGGTGGTCAGCTCATAAGAGTATGGTTCACCACAACCCAGAAATACCATCTTTCAGTGCCTTATACTGTAAAAACACTCTGGCTCAAAGTGCCCCAGAGGCCCTGGGATCTATCCTTACCCTGGAAAACTTGTGTGAAATTTCGAATATTCACAGCTACTAGGTTCGTAGCTCTAGCTCAATGTTCCCACTCTGCCTTCCACAGGACGTATTTCTACAATATTTTGCACAACTTGGTACAGTACTCAGCTTTCCCTTTTTGCACCAAAACATTATTGATCCTTACGATTAGCGTCCTAGATAGGCTACGCCATCGAGATCTCGAATATGCTAATTCTTAGGAAAGAGTGATGTTTCATCATCTCCTGGGATTAAAAATTTCGGAGGAAGAACATGGCAAAAATCAGGTTGATCGTGACACTCGTCGGGGGCTCCTCTCACTTCTTCCCCATCTTCATCTCTCCTTCTCTTTCCCGATCCGATCTTTTTTCCTTTCTTCCATTTTGTTTTTCCTTTCCATTTTTTCTTCCTTCTTGTGTTTGATTAGCCATCCTCCTTGGAGCCCTTTCACCTTGTTTCATTTTTCTTTATTCAGGATTGAATAGAGATATGGTTCCGTAAAATCAGTAATTCCAATACTAGAAGAATTAGTAAGACATTCGAAGGGGGGAAAATTCCGCGCAAAAATCGACAGGAGGTTCGTCCGGATTGGGTAATCGTCGGAGAAATGAAAAATCGCGCGCGCTCGCCCGCGCAGATGAGATATATTCTAAATCACATGGTCAGCGAAATGATCTACGATGGATTGCGTGATCTATAGGCGTATCAAGGAGATTAGCACTGCTGGGCGTCGGGATTCCTTGAAGGAACACGATCTTTGAAGGAGACGAGGAGGTTGTGAAATTTAATTGTGATATCATTCGATTATGTACTGGCCTAGAATATACATCATCTTTGAGAATTCTGGTCGGCTGTTTTCGGGAAGTTCTCAAGGATCGGCGCAGCCATGTCTGTAGGAAGTGCTTATGCCAACCCCAACACGTCACCTTCTCAATCTACTACTTAGAAGTTCAGTCCTGCCAATCCGCACGCTCCCACCACAATGTCTTCGTCGCCTATCCGTTTCTCCTGTCGAGTCTCGGGTCAAGGCAAGTGTGCGTGTGTCCCTTCAGTCGTCGAAGTCTTAATCATTTATTTTTGCTGCTAAAGTCCGAACAGTTTTTTCTAGCCGTGTCGGCGAAAGGGTTCTTATTGCGAATTCACCTCCTCCCACCCGAGAAATGGCCCCCCTGCCGCAAAACGTGACCTAGCATTAAATAAAAACAACACAAAGCGCCTCCTGCATCATCACGCGTATATATGTATTGTTGAAATATAAGATGGTAGGCGGGAAGAGGAAACGACGATCAAGATCGACTGAAGGTTGCGCAATCGAGATGGTCTCTTCCCGGCACGAATACCTCCTCCTCGTACAGCGTACCAGGCACCCGCATATAGCTAAAGTTCTCCGCCCATTTTTACTTTTTTGTGCTTTAACATCGCAGCAGCGCTTTTGCCATTGCGCCCGACCCGATCCAACTTCTTATTCTTGTTCCTCTACTCCCCCGCCCATGTCCTCCCGATATCAAAAAAGTGGGAGGAGCATGCATAGTGAGAGGGCGGGGCCGGGACACACACAAGGCTGGCTCAACCCGAGAAGAAGGAACAACAATTATGCCGAGGACAGTCTCGACAGGCGGCCCGACCTGCGCCTTGATTACCCCGCCCGTCCGCGTGCCCAGCCGTGCACGGCTATCTTGTTTGCCATTCATGTTCCTCATTCGACGTTCATCATGCTTCGGTTATGCTTCTTCGTGTTGGTCCGGTTTTTCTCTCTCTCTTCGGCCCTCTTTCTTCATTGGACCAGATGCCATTCGCCTTTTTGTCGCCTAGATAAGCGCATATTTCTCATCTCTTCTTTGTTTTCCATCATTCATTATATATCCAATATCCCACATCCTATATCCTCGTTCTCTAAGTCCCTCATTTTCATTCATATGCCGATCCATTTGGTACTGGTGGTGTCTTCTTAGTTTTGCTTTCCCATTCCTAGACAATTCCTTCTATTTCCACTTTTTTCTACACAATGCAGACAGCCCATCCCCACGCGCTGCCCTTGCTCTCTCCGATCTTCAGCCACAAACCGGCGCCTCGATCAACGTTCTCAATTGGCAGTGGATCAGGCAACTGGTAAGTCGAGTTCTTATGTAACTAGTAGGATGGTAGACATCGAGCTTAACGATGTCTGGCATTCGTTACGTACGGGTTCTCGCGCCGCCCATCGAAGCGCTTGAGCGCCGATTCACGGCTTTATCTCACCCCGGTCTAGCAAGTTTTCCAATCCATCCCAAATTACAGGACAAGCGGTGTTGGTGATGGAGTTAATGGTTACATGGACAAATGCGGAGGAATGTTCGGAAACAGCAGAAACAACGTGAGTTATAAAAACTGGGGGGGGGGGGGGGGGGGGAAGTGCTGTTATAGGCGTCCACAGGGACATTGAGAACCGCGTGATGAAGAGTACTTTTATCCGAATTAAATCATAGGCTAAACGAAAACAAGCATCAGGTTCTTGTGCTTTGCACATCGGAATATCCATCTCAATCAAAACGCGGGAAACACGAAAGCCTAAGCTGGACCAACTAGTGTTAAATGCTTAAATGCAACCCAAAAATGAACAGTCTATCACTTTCATCTTCCTGTAAATCAGAGAACCTGAAGCGCTGGCAATGCGCACACTTACAAAAAGTGAAAGCCGATATATCAAGCTTATCACCTAGCGGGACTTCGCCCATTGTCTCATTGTCTCTTGGCTATCCGTCCCACCCCCCCGGATCATCCGCCCCCTTTTATCACTCTCGAACAGTTTCGCGCGTTGATTCAAGGACCGATTCGCATTCGGCAGCAATAACCCGTCGTCCTGCAAGCTGCTTTTCATCGAACTTCGTCAGGCGGACTTTTTTCCAGTAGTTAATATGTGAGTTTTTTTTGTTTTTTTCTTCTCCGAGTTTTCTACAAGATCCATTAACATTTAGAATGAGATTCGGCAGCCGGTTTTCTTGATTCTAATCTCAATAATTATTTCCCAGTGTATATAGTGACACGGACAAGTTGCCCGATTGCGAGGAAATACCAAAAGTCTTGTGCTGTACCCACGTGTCTGATAATATGTCTGTCTGGTCGAGTTGTTTCACTGAGAAATACCCCCACAAATTGGAAAAATACGAGACGACCGATGAAGAGCCACCGATTCGACAAGAGCTCACTGCAAAGAAGCAGATGAAGCCAGCTAAGGCAACTAGCAACAGAGTTGTCGGAGCAGTGCTTGACGTAGACCATGAAGCCAAGGAGCAGTTCATCGACTCCAAGGATATCAGAAGAGCACCACGAGTCGGTCAAGCTTCTCAGCCAGGAGTACCCGATCACGAGGTCAACGACGGCGACCGCCGAGTGCGCAACCGAGAAGTCTCAGCCACCATTCTCACCATGCTTGTCCCGCAAGTCGGCTGACGAAGTCTTCCTCTCCTGCTGTCGCCAACAGGTTCCATGCAACTGTCACTGAGCCTCTACAGAGCATCGTAAGAACATGTCGCCGCTGAAACTTTGATCCAGGCGATCCAGCAAGAGCACTGATGAAGGTAAGAATAGTTCAATCTTCCTATTGAGTTTTTTTGAGTTTTTCCAAAATTAATTCTTTCAGTACTTCTCCAAATGCTCTACTGTGCGGCCAACCAAAACCGCGACAACCGCGCGTGCGCTGCTCCAACCTCGGCATGTCAAACGCGGAACTCGGCGTCGGCGATCGTTGCCTATGTGCAACATATCCCCGGCGGGAGACTGTGTAAGCCCTATGGAGAAGGAGGATCTCGTCTGCCGTCCAACTGGAACGTCGTGATTCATGTACTGTGCCAGAGGTGGTCTTCGTAACTTGGATCAACTAGACCATCATCCCCGTTCTCTTCTCCCGTAATAAGCTGGATCAGGTAATAATCAATCGCCGATCCTCGTCTTAATAATTTTCGCCCAATTTCCCATCTCGTCCCCCCTTTTCAACTCTACAACATTTCTCAGTGATATTCATCTGAACCGCCCGACATACATCAGTTCCTCATATTCCTAACAGGGTTAAACAAACCCATCCACACCGTCCCCCCACGTTTCTGAAGACCCCCCCCCCCCCCACTTAAGGACCCCAAGTCCTAGTTACTAAATGTGAAACATAATGGCGAGACTGCAATACTTGTCCCCTGAATCCATGTTATTTACATGATAATCTATGACATATACTTTTTTTTTAAAACACAAGCCCCCTTGAAAACGAACCTCATCATTGTATGTCAAACGGAACCTCTTATTACACGATTAATTGTTGAAGTTTAGCGAATAAATCAATCATTGCTCTCGTTGGGTCTATGCCCACAGCGAAATGACCCGGTGCAGAGATAGATAGTTAGAGGGTCATAGACATCCGGGACCCAATGGGGCCGCCCGCGGAAGAGACGATTTGTGTCGATTTACGAAATGATGACAACCAGGAAAATTTCGTATAGAATCGACACAAATCGTCTCTTCCGCGCGCCACGCCCCATCGGGTCTCGCGGTCGCTCTATAACTATCTACAGTCTCTGTACCGGTAATACTATTGCAGTAATCGCAGGTCTTAGCGATTTTTCATAGCTTCACGTATTTCTCGATTTCCTCATAAATTGAATTGGATGCCTAGTTTTTGCTGAACTAGGGGCCATTTCGGCTCGTCAGTATATGGTGGGGTAGATTTACGGCGCTTTGCGGTTCGATACAATTTAGTTGTAAAACTAAATGTATTTGTCCGTGTGGAAAGAAGTACACGATTCACATGCGTGGTCCGACAGGCATCAATAGAGCGCGAAAAATTCAATGAGGAAGGTCAGAACTCCGTGCAACTTTACTCGCGAACTCTGGTGCGTGTTATTGTCTTTATTCAGTTTTCTGAGACGTAATGAATATACTTTTTTACAGCAAAACTGGAAAACTGATACAAAAGTCTCCAGAAACTAGATATTGAAATTACAGTACACTTTAAAGGCGCACAAACCATTTTCACAGTAAACAAAAAGTTCGTGCCGAGACATTTCATCCAGATTCTCAGTTAAAATTTTACAACACTCATTTTTCCTTGAATATTTAATGAAGTAGGTTCGAATGGAAAAGAGAAGAAACCAAAAAGTGAAATTATTCTCAAAAACTTGATTCCCAAACCGGTATTTCGATTTGGCTATTTTCGACCAATTTCGGCAGAATTTTTTAGCAGAATTTTACAAATTTTTTAGAGTTAAAGCTTATTTTAATTATTTTTCTCTGAATTCACCTATATATGAATATCTTTGCTTTCGATGGATCTTCCTCAAAAGTACACATTAGTTTTATTTTTCTACAAAACTGTGCAAAGTTACGTCGTGGTGTTTGTGCCTCGGATTTAAAGAGAAATGGCATTTTTCAATCTTTTGTCGCAGTTTTTCTGCTTTTTTTTTCACCTGTTTTTTCGTAGTTTCCTAATAAAAAGATCGTCAAGTGTTTCCAGGGGTCATGGCTGGATTTGAAATTCAAAGAGTCGAGTCCAAATTCTTCGACTTGGACGACATATAATCGCCAAAGACTCCACGTCTTGAACATTTGAGATTGGTGATTTGAATCCAGGTCTGAAATCGCATTGAAGACCTAAAAATTCTAGTGATTTTCGTTCTGATTTTTTCCAGGAAATGTTGGGAGTTTTTCGAAGCCAACTCAAAATGCAGACGGATACGGCGTTGATGCTCCATACTTGCTGCTGGAATCCGTTAGGAGTTCATTGTCCGTGAGAAGTTATATTTGCCCCGAATTTTAATTTAGAATTCCAGATTGACCCCCAAAAGCTAGTGTGAACATGCGAAATGTCTTTCTGAACGCTGACAGCAAGAAATTGTATCTCTTGAGTCCGGCTTCGCAGCAACACTTTTACGGCAACGGGGTGCAGTCGTCTGCATGCATGAAGAGGGCGAAGGAATCCGGACGGCGCGCTGAGCCTTTTCCCGCACGCACATGCCTTGTACTCCACACTTACACCACTCAGGGCTTAGGAGGTATTAATTAATATAATAAAGCACTTATAAAATACAATTCCTGGTTTTTTTTTGTTGCAGAAATTGTGCTCAACTGCAACACATCTGCAAAGGAAAGGCGAGAAATTCGACAGCCTCTAGACAAAAGTGAGTTCCTGGAGGGTAAACGGTGCAAAGATTGATACTTGGCTGAGACAAGACAATACGTGCTCGAGCAAGAAGCAAGAGACTTTCGTTATAAACTTCAAATTTCTTATGCTTGAATCTAATTTTATTCTTTTTAAGTCGACTGCTCTGTGAATATAATTCAAATCCCCATTCTGTAATATTTATTTTCTACTTTTTTCACACTCATTTTTGTGTTGTATTGGTGTAATTAACCTGGTTTCATGACTTTTTTGCAAGGAAGTTTGTTGAAAACGCTGCTGCAAAATTTGCCAGCAAAAAATTTTGTTCAAGCCCGCTCCATCGCACAGTTTGAACGTCGCGGTTCGAAGTTAGATGTGCAGGTCATATAGCAGAGAAACACTCCCTTTTTTTCTCGAGAAGTTTCACCAATTTTGCGCGATCACCTATTTTTTTGCTTTTTTGGCCTAATTCTCAGATATTCCTCAAAAACTTGAAAATCCAATCTAGAATAAGTGGTAATGGGTATATTCTAGGATTGTGCAAAAGTTAGCTTGAATTGGAATCCTCGATTAAAGCTTTCCTACCAAGAAAAATGTGTGGATATTTTGTACAAGTTTTTCATCTTTTTTTAGTAATATTCTCTGTGAAACTCCTATGGTTTCTCTCAAAGTTGTAAACTTCATAAACGCTGTCAGGGTTACCAGATTAAACAATGACCGGGAGCAAGCACCTAAACTCACCAGAGGAGAAAAGTCAAGGAGGTTGGTAGTTCAACATCTAAAATATTTAAATTTCTATATTTCAGCCACAAGTTGACGTTTCGATTCCCGACAACGAGGCCGTCGAGCAAGCAGCTCACCGTGGAGCAAAGACGTCTGCCCGAGGCTGCTGGACTTGGAGATCAACAAGCAGGCCAAGCAAAGCCGCTCCGAGAAGAAGGCCCGCCCTTAAAGCTCTTACGTCTCCAAGCGCGGACTCGAGCAAGTGACTGGAGTCTCCCGTGTCTGCATTGCAAGTCGAAGAACACCTCTTCGTCATAAACAAGCCAGACGTGTTCAAGTAGCCCAGCATCTGACACATCATTTACTTCGGAGAAGCCAAGATCGATCAGCCAACACGCCCAGTTGTATTGAGAACTGAAGCCAACTCGTGAGACCCCACAACAAGACTGTCGAAGATGAAAAGTCGAGAATGAGGATGTTGAAGTAATTCAGTATCTTAATATTTATTACATTTGTACGGTTAAGGAGGTTTCCACCGGCATTGAGGAGAAGGACATCGAGCTTGTCATTTCCCAAGCCAACACCACCCGCAAAGGCCATCAGGGCGCTTAAGGAAACTGACAATGACATCGTCAATAGGGGCAAGCATCATGAGCCCTATCTTGTAGCTTGTTTCCTGATGACTGAGCTTGCAGATACTCTTGTTATCGTTGTATCTCTTGCTTATCCCGTTTTCCGTTCCAAGAAAACGTTTATTCTTTTTTAACCTTTTTGTTATGTTAAAAAACAATTGCATCTTCGATACGAATTGTACAACCTACCTTTTACAGAAAAGAACAATAAAATCGCTGTTTGTGTAAAACACCCCTCTATTGATCCAGAACTCTCACTTCTTACAATACTTTACTCGTATGACTGTGATTCATCTCACCTGCTATCACTTTATCATGACATTCAAGTTTATATCAACAGCAAGATACCATTGTGTGTATGTGAAAAATGCTATCGAATAGCAAGCGCGCCCCAACAAATTTGAATGCGCGGGCGAAATGGTGTTAGATGTGCAGTCATATGAAACGAAACGCATCGACCAGCAGCCAATGGGGTACAAGTTACTGCGAGCTGTTAGATTTTTTCACACGGTTTCCAGTGTTATCAGGTGATGGGAAATCGATCCATAATACTGACTATTCGTACTTAACATCTTAAACATCCCCACCGTTTCGCTGTCATTTTTACCGATGCGGATTTATATTTCCTTTCTCGCCGACTTTTCATTTCTAAATCTTCTCTGAAATTGCGAAATTTTCAGCCTGTTTCATACGAGATCGAACGGCTCGTAATGAACCATCATCTCAGCAGCCGTGTAGTACCGGGAGTAATGCATGAACTCCAGCAGAACAAAACGGGTCGGCAAAACCTTCAAAAGTCACAGTAAAAGGTAACAATTGATTTTTTGCATCTGTGCTAATAAAATTTCCCCCTCTTCCCTTAATCATAGTCGTCAACGCGCTAGTTCACCAAGGCAGCCGACTCAGCTATTGTCGAAATCACGGACACGTCATCGGCGGCGCCAAAAATGACGACTGCAAAGAAGAAGACGATGGCGCCCGAGTGGAAAGAACATCTCAACGTTCATGCAAATGAATCTTCGACAATTTCGTTTCGTCTATTGCAAACCGTAAAGCCAAGCTATGACACGTATCTAGGGATGGCGAAGCTGAAGCTCTAGTTTCGAGTCTCACAAGAAATGAGAATGGAGTAAGTGGTTTTTGTGACTGAAATTTTCTCAAAAAAGCTATTAGTTCAGTCAAAAACGACATCAACAATATATCTTTGCTGGCCAAAGACTCCTCGAAAATCGGAACTCACTCTCGACATAATTTTCTCCGGATATCCAGAGCGGAAACGAAGAAGCGCAGGAGTACGAACTGAAACCGCCGCGTCTCCAAGTTCAGAGGCAACGTCAAATGGCGTTGCCACGACATCCTCGGCGCGGACACCTGGCCGGCGTCAGCGAAGCGTGACACTTTGGCGGCTCCAACGGTACTCGTGACGAGACCCATTTTGAATAATTTAATTATTCATGAAACGCTCTACGGCAGTGTTAATAATTATTAGAGCGCGCTCGCGCGAAAGCACCTCACCCAGAAGTCGCGAGGACAGCAGTCTCTGGCTATATTGGCTGCTATGGAAATTATTATTTTTTGATTTAAACTATTGTTGAGAAGCATCATCCAAATTGAAAATGTGTAAAATTATGATTTGTCCGAAACCTGAAGGTTTTACAGAGGGGAGTCACCACGGCTTTCTTAAGTATCAGTACCGTCAATATTTCGAGTTCAGAAAAATATGTCATTTTGTAGAGAAACTCTGTTACTTCACAAAAATTTCCATGTTTGATATTTTAATTGTTTAATTTCTAATAAAATATTGCAAATTTAAATCAACAAGTATACGTTAAAACCGAACCTTTTTCAATCGTAACCTCAGTTTTTAATAAGAACACTTTCATAATTTCAAACATGGATTTGAAACAGACTTTTATCTACAAAAATGACATATTTTCCGACTCTGGAATCGAAAAAACTGACGGTACTGAAACATTTTAAAGAAACTCGTGGTGACTCAATCTCTCTGTATACCGTGGTTCACTTTTTGTTAAAAATATTTCCATCCAAAAATAGCCAAAAACTGCTGTCCCCTCCTGCGAAACGAAATCCCTCGAGTTCTGGAGTTCGTGAGGTACCGCGCGAGCGCGCTCTAACAATTATGAACACTAGAGGAGAACGTGAATGAGCGTTTTTTATTCTTTTCTCTGCTTAATGCTACAGAATCGTACACTAAATGTTGTCAAATACATGATGCATTACTCCAGTCTACTACTATATGTTTACTTTTCATTTGTACCGCAGCGGCGGCAGCCAACAGCATGCGGCACCCCGGCCGCCGCAGCAGAAGAGCTTCCCGATGGATGGGAGATGCGTTTCGATCAATACGGACGCAAGTACACCTGTACGTGGCTCACACCACCAAGAGCGCCACGTGGGAACGCGCGTCTTACTCATCCCTTACAGGGCGATGGGAAATCCGAAGAGATCCGAGAGGAAGAGTGAGTTTTCCGAGGCTGTAAAAGCAGATTACTTAGCACGAGAAAAGCGTTTCTGATTATATTTTCGATGCGAAAAGCATCAAAATTAAAACTATCTACCGTCGCCGCGGATACCTGGACCAAAATGCCGAAAAAAGTGACTAAATTATTTTATAAAATCTAGATTTTTACATAATTAGTGTTATTTGATGATTTCTTGTCAAATTTTTGTAATTGCATCGAAATAGTCCAAAAATAAAGTAAAAATCCACTTCCAACACAGAAGAACTGACAAAATTGAAGATTTTTGCTGAATTCAGGCAATTTTTCGTAATTATTATGATCCTACATAAGTTTTTGTTTTCGAGATATTCGAAAATTTTTTTCTTTAAATACGGCCTGAAAATTAGGAAATTATAACGACGGATAACGGTCAATTCTGATTTTCTTTATTTTAACCAAGGTCTCCGCAAATTATTTGATAATCGAAAATAAAAAAAAAACTTTCCAGTGATTTTTACTTGAGGGAAAAATGTCTAAAATTCACGCCAGGTGCACAATCCCTTTTCAGGTGTATTACGTGGATCAGAACACGCGCACGACCCCCTGGTGGCAACGACCGACAGCCGATATGACTTGAACCACACGAACAATGGCAATCGGGAAGAGATCAGGCGATGCTTTAATGGGAACAAAGTTTCCTTCTCCAGCAGATCAACTTTGCATCCACTCGTGACCATTGCCCGAAGGATGGGGCGTCAGGATCCGAATACGTCGAGATTGTACTTTGTGAATCATTTAAATAGGACACAATGGGAAGATTCGAGAACACAGGGGTATGTGAAAATTTTCAATTGTCCAACATTATTTCTATCAAAAATCACAGTTTTAATGTTTTAAAAGTTTCAGAGGCCCGACCAACCTTCAGGATGGTTTGGAAATGCGATTCACCGAGCAAGGGCGTTCGATTCTTCATCGATCACTACTCTAAAACCACCACCTAATAATGATCGAAGAAGCGGAAAACCCGTCGGCCCGCTCGCCGTCGTCGGTGTTCAAATGGCCATGGAGAAGAGTTTCCGGTGGAAAATTGCACAATTCAGATATTTATGCTTGGTAAGGGAGGGCGAGAAATTCTTTGCTTTTAGCTATAAATTGATGAAAATTTCAGTCAAACAGCGCCTAATCATGTCAAAATCACAGTATCCCGTAATAACGTGTTCGAAGACTCATTCCAAGAAATTATGCGTAAAAATGCAGTCGGTCTACTCCGGCGTCTGTACATTCAATTCCGAGGGGAAGAGGGTCTCGACTATAGAGGCGTCGCCAGAGATGTTAGGGTTCTTCCTGCCGCACGAAGTGTTGAATCCAATGTATGGGCTTTTCATGTATGCTGGCAATAACTATTATAGTCTTCAAATCAATCCACCTTCATTTGTTAACCCGGTCTTAAGTATTTCGAGTATATTGGAAGATTCATTGCCATGGTGAGTATTTTTTTTTGCAATTGTAAATCAGTTGAGAATTGGATGAAAAAATGCGATCGACATGGGGAAAAGCGAGTTTTCCGCTTTATACCATTGAATTTTAAAATTTTAAACGTTAAATTGAAAATTCAAACAAAAAGCACTTCTGGATCTAAAATTCTTATCGTTTTTTGAGGTCCTTAAATATCGATTTTTTATATTTTCAGCACAAAAAGAAATTTCGATGATCTCAAATTTTCAGATCAATATATTTCATTTTCTCGGGCCTAAAAATGTTATTTTTATTTAAACAAATAGTTTTTCTTAGAAAATTCCTTTACTTTCAAATTTCCAGGCGCTATTCCACGGAAAATTCATCTACAGCGGTTTCACGATGCCATTCTACAAAAAGATGCAACAAGAAGATTGTTTTAAAGGGCATTGAACAAATCGATTCGGAAATTTATAATTTATTGATGTGGAACCTCAAGGATAACTATATCGATGAATGCGATATGGAGCTCTATTTTGTTGCCGATAACGAGCTACTCGGCGAGCCCAAGACTTATGAGCTTACGGAGGGCGGTACAGAGATTGCTGTTACCAACGAGGAGAATAAGGTGAGACTTGGGATTAGCTAGAGCTTATAAAAATAATTTTTAAATAAAATAATTTAATTTAAAAAATCCCAATTTTCCAGCTTCAATCCATCGAACTGCTCGTTTGGCGCCGCTTCAATCGCGGTGTCGACCGCGAAGACAAAAGCCTATCTTCACCGGCTTCAACCCGGTCTACGCGTTGGAATGGATGGAGTATTTCGATGAAAGAGGCTGGAGCTCGAGCTGTTGCTCTGCGGAATGCGGGACGTTGATGTGGGATTGGCAGTAGAAATTCTGACTACAGACATTATGCTCCACAGAGCAAGCAGGTAGGGGAGAACATTTGATTAAAACCTTTATTTTTTTTTAATTAAAAAATACATTTATAGGTAACCCGGTTCTGGCTATGGGTTCGAAGACCAACCGTGAAAAACGTGCCCGGCTCCCACAATTCGTCACATCGCGGACCGTGCCGTGTGTCAGTCGGTGGATCCTGATTCGACGGGACCACAGCTATTCTGTATCGAGCGTATCGGCAAGGAGAACTGGCTCCACGGTCGCATATGTGCTTCAATCGACTCGGCTTGCCGCCATACAGAAGCTACGATCAGCTCGGTCGGGAGACGAGTTGAGGATGGCGATCGAGATGACGGAAGGATTTGGAAGCGAGTAGTCCATGTCCCGTTATTTTTTTTTGGTTACTTGCTGGCCGCACGTTCAAATTGTTGTCTAACCCTCATATTTCTTCCCACCTATTGAGGACCTTTTCCTTTTTTTTCTCTCCATCACTTAATGTTTCTTTTTTTCGAATCGATGTTGTGTGATAATTTTCGTGTAGTGATAGCACTTGTGCTTAGGTTCTCTCTGCCTCTCATTCCTTTCCTTCGCGTATGTCTACCTATAATGTTTTAGAATACTAGACAAATCGCATCTAGTTTTTTTATTTAATTTCCAAATTTCCCGTTTAATTCCAACAACAAAAAAACAATTCCACCTAGACACTTTTCAAATATTTTTGCGTCCATTGCTTCATTGCTTTTCTTCTTCTCAACCATTTCAACAACCACCACCCAATCTGCGCCTTATCCTCTTACTTGGTCACTTGTCATTCTTACAATTTTTTTCACGGAAGCAGCTCTAGATTATTAATTCAAATGCATCCCCCCAACCAATCCGTCACCCCCCGATTAGAACAATTTCTACTTTTTTTTTTGAAAACAAAAAAACACCTCGATTTGGTTGTAATCAATGGGAAATTTAATTTTTTAATCTGAGCCTTCTTTGTTGTTTTAGGGTTTCTTAACTTTCAGAATTTCCATGCGGAACACACGGAGAGCACAAGATCAAGATTTTGAACCCTGCAGGAGAACGGGACCCTTAGCGTGGTCACTCATGTCTCGGCTGTCTGTGGTTCTCTCCTCTCTCTCACCAGCGGAGAGGATGGATACCTCATTCGCTTTATTTTCGGACTTTCGATTTTTCTTATTGCTCCACGTCTTTTATCAGATTCGGGGAGCTTTTGCTTTTTTCTTGATTTTTTCGTAAAGTGTTCCTGGGTCCCGCAGCGAGAATTAACTTTAAAATGATTTTTTAAAAACTTTCAGTTAAAACTTCATTTTTTTTTCCCATCATTTTACGACTAGAAATTTCGAAATTTGAAAAAAAAAACCGTGTTGCAAATGCGCTCCAGCGTACAAAACGAAACCGCCACCAAAAGCTGATTTTAAATAACTGAAAAAAACGAGATGAAATTGAATTTGTTTTGCCATTTTCCGACAATGATTTTTTAAATAAAAAAAACTGTTGCACAACAAATGCGAGCGAACTAACCTACCAATTACCGAAAAAAATTATAAAAATTGAATATTTCCGATTAACCCAAGAAAAGAAAAATTCAATGATTTTCTTGAAAAAAGTTACCATTTTCTCAATTTTTCGTTAATAATACTCAAAATTAGACTTGAAGAAAAATTGTGTAGCAAGCGAGCTCTAGCGAACCAAACAAACTGCTTCTCTCCATTGAAGAGTTTCAGAGCCGAGGTTCTGGCCTACCTCATTGAATTTTTCGCGCTCCATTGACAATCGCCCGCCCATAACAGAGGGCGTGGGAAAGTCGTCTGGTACTCCACACGGACAAATACATTTAGTTTTACTACAAATATCGGGCCGCGACGCGACACACGCGCCGGTAAATCTACCCCAGATATGGCGAGCCAAAATGGCCTCGTTCGGCAAAAACTCTTCCAGCACTTTCAATGCATGAGAGACAGAAATCCGTGATACGAGAAAAAATAATCCCAAAAAGTTCAATTTGCAAGGGCGCTGCATTGAAAACGCGCCGATCCCAACTCACGGTCGAATTTGAATTTTTAGTTGCAAAAAAAATCCACCAAATTGTGAACTAAATAATTTTGCAATCAATTCTCTCCCTAAAATAAATGGTTCAGAGGAGTTTCTCGAATTCGTAGTTGATACCCGCTCGTCAGAATTGGAAACTGAGAAATTGAGAGAGAATTAGAGAAGGAGAGGAAGAAGAACTGCTCACTGGTCCCCTCACTCCCGGAAATTAGGGACTTTTTGCTCCGGCGGGCTCCCACTAGAAGACGAAGAAAAAACGACGAGCAGAACACAATCAATTTCTTCTTTTTTATTTTTTTTTGGATTTTTTTCTTGTTGATACCACGGATTTCTGGCTTCCCTCATAAATTGAAATGGTAGAGTTTTTGCCGAAATAGGCCATTCATTCGGCTCGGCCATATCTGGGGTAGACTAACGGCGCGTTGCGTGAGTCGCGTCGCGGGAGTTTAGTTGTAAACCTAAATGTGATTTGTCCATGTGGAGTACACGACTTTCCCGCGCGCTTTATGTCCTGCGGCCGATTGTCAAAGGAGCGCGAAGAATTAAATGAGGAAGGCCAGAATCCCGTGGTAAAACATGGTGCATCAACGCAAAAATTTTTCATCTTTTGGAAAAAGTCAATTGTTTTTTTTTCGCGTCGGGACCACCTAACCGCAGCTCGTTTAATTGAATTTCCCAAAAAAAAAAAATTTGCTCTGTTCAACCAAATTCGAAATTCAGTTTTCATTCCCTAAAACCTATTAAAACGATCGTGGCAAAATGCTGTGAGCTTTGGGGCTAGAACGATAGGCCTAGAAATGTTGAGACAGTTTCCTCTCCCAGCGCCCTTGCCAATATAGAAATTTCAAATTAGTATAGCTCGGCCATTTTCCATCCGCACGGTTTTCGCCAAAACTACACCCCATTATAAGATTTAAAACTTACTTTTCAATCATTATGATGATAATACTTATCCAGTGGAAAAATTTTATTTCCACCAAAACCTCTCCACCCGCCGTTTTATCAAACAAATGATATCACTATGATTTGTGTTGTAAGTGCACCATGTGATTGCACTTGCGCAATTAATTAAGACAATCTCAAATGTAAGTTTGATCGAATTAACCCCATGTACATATAAAATACAAGCTTTTTGTGTTCTTCAAACAGTTTTTTGTCGTATTTATATAGAAGCAGTGTACACCTAAATTTGGCTTATTATGACCTTTTTTTCCAAGGAATACTCATTTTTAGGGTTATAAACGGCCCTTGATTGAGGAGAGAACTGCAAGCGCTTTTTCCTGGGAGTTTTAGGCCACCAGTTAGAGTCTTGCAAAGACGGACTAGTTCTCACAGGACCCAGAAAGGCTTTACTTAGTCCATCACGAATTTCTGACGACGCCTAGAAATGCAAATCTTCGGCCACCTCATAGACATTCTAGGCCACCCTTTTTGACGTGGCCTAGAATCTTTAACAAAATTTACGTAATGAGAAGTAAATCCTAGGCTGTCCCACTATTCAGTTAGCTCTCATTTTTGATACTTCGCCTAGCGATTTTTAACACGTGGCCTAGATAGTTTCTATTTTAACACGGGGATTAGATTTTTATGTTAACAAGCTGGCCTAGGTTTGCTACTAGGCTTAGATTTTTTACATGTGAGCTAGATTTTTATTATAGCTGACCTAGATTGTTGGCATTTAGCCTAGATTTCTGTCATGTGACCTAGATTTTCTAATGCACCAAAAATTCTCCATACAAATTGATTAACTCCTACAACTCTAATTGAGGTAATCAGAACCTTCGATAAGAACATGGAGCTACTGCGGTTCTCAACTTCCGAAAAAGCGGCTGAAAAACTGAGGTATACCTGCTTTTTTCGAAACTGATAAAAGTCAGCATAACTCACGATAACTGAACGTCCCTTGGCCAGGTTGTAGGGGGTAGTGGTGGCCGAATTTTAGGTAGAAAAAACTGGGCCACGAGGTTTACGTGGTGTAAAATGTGCCCCATTTACTATTGGTTTGACCTTCGAAAAATCCAGGAGACGAGACGCAGACTTTGCTTCAGCTGATTTCGCATGGTTAAGAACGTGCTGATGTCATTTTTTTCCGTGGCAAAATTCCCGCATTTTTTGTATATCAAACCACAACGAGACACTCTAACATGAACCACCGTCCGGCCTCAAACGAAAATCTCGGCCACGGCCACTAGGGTGAAGTGGAATGCCCTCCCCTTCTCTAGAAAATTCATTGGAGAAATCAACCCATGCTCAAAGAAACAGTGGCCGAGAAACGAAAAACTAGGCCGCGTTCTAGCAGCTTTGTACCTCTCTTATAAAACACTGTCTGTTAGTTCATAAATCAGAATCTGCGCCCTATCACTACTCTCTCGTTTACCTGCCCCTCTTAAAAAACAATCAACCCCCCCCCCCCCTCTAAATCGACTACTGTTCCCCGTTGTACCTGTCTGCGGCTAGCTATTTCGGATTTTTGGAACGAAAAAGTGGTATGTGAGAATGTACGAAACAAAGCAAACTAATAAGAGGGTCAATTGTATGCATTTTTTGCCCCCCCCCCCCCCCCCCTCCACCCCGCTAGCCTGGGAGGTCTCAAACCGGTTTCCCCTTTTTCACCTCAATCAGCCCCCCCCACCCCCCCCCCCCCCCCAATTTCATTTCACTGTACATTTTCCTTAACCTATCTGCGTATCTACTTTTGTATTTGTTCCTTACTTATTTTTCTAATTATAAACCCTGCAATTTGCAAGAAAAATTCTAAAACCCTAGTCTGGCCCCTTACCCCGTACGGGACCGTGGCCGAGAAATTTATATTTCTTATAAGACCCCCCGGCTCTTCCAGTTTTTCATTTTTTTTCATTGAAAGCCTAAATTTTCATATTTTCTTAGAGATCAAAATATTATGGGTTTGTCAAAAATTTCGAAACAACAAGCTCCCCGTGGGCGGAAGAGTTTTCCAAATTTCTATACTTAGGCGTTGGGGTACGCTCGTCGCACCCTCCCGGAGTACAATTGTAAATTATAAAATTATCATAAAATTGGCTCAACGCATTTGAAAATAATAAAAAAAACTTTAGAAAAAAAAACACGAAAAAAACCCCTTTGAACATGGTTCATCGACCGGGACATATGTACTGTGAAAGCTTATATCTCTGCGCTCCATGTTTGTTTCATTAAATTTTTCAACCAACTAAGTGTTTATTATCTCTTTTCTATATTTTTGTAATTAAAAAGCTTTTTGATACTTCAAAAGTAACTGAGATGCATGTTGTGAAACAGAGCAAACTTTCCTAGCTTAGCCCAATTATTTATATCTGTGTTTCGTGTATAAACTTTTCTAAAAGTTTACGGTTTTTTTAAATTTCTAAATAAAATTATTACATGACTCTTTGGGAGGTCATGCGTTGTAGATAGCATGTACAAATAAAACTGAGGAACTAGGACGAACTGAGAAATTCCTAAACCATTATTTACACATGTGATTCTTGCCTTTTTCGGTGGAGGGTTAAAAAGGTTAAAAATTATTTAAGGCTTGGAATGAGCATTTGTGCGGCCGAGGTTCCTTTTTATTTTCTAGGCCATAATTTTTACAACAATGGCCAGAAGCACAAATTTGTAAGTAATTTGAATTCGCCAAAATTTTTTTTTCCATAAAATTTAAATTTCCACCGTGGAAAATTCTTTTCGGAAAATTTGTATTTCCCGCCCTCAAAAGATTTTTTGTCTCAAAAAATTGAATTTCCCGCCAAAATGTTTTCGTCGCTCAGGAAAAAATTTCCCGCCATCAAACATTTTTTGTCTCAAAAAATTTGAATTTCGCCCACCAAAAATTTTGTCCCAAATTTTATCGAATTGGTGGAAAGCCGAATTTCCATTTTCTAGGACACTCTCAGTTAAGTCATCAAATAAGTTGACTTAAATTAAAATTAACAATTTGTCTCCTACCATGAAAATTTAATAATAGGCTGTATAGAGCATCATGGGCGGGCGGGGTAGCATGAGTGAACTTACCGGTTGACCGTCTATACATAGTAACACCCGACCATTTTCTGCCAAATACATATAATATCGCTTCGAGACCCAACTAATGCGCAGTTGTGCTTTATTTCGGTTGACAAGACCCGTAGAAATATTAATTTACCTACAGGTGCTAGAGCGTTTTAAGACCTAAAAAACTAAGCAATGGCCCAAAAATCCAAACTTAAGAAGCGCCTATAATTGTGCCTCGTGTTCGGGACCCAAAATCCAACTAGGCCATATTGTGAGCTTGGTGAGACCCACCTGTCATAAATATCACTTGAGTCAAAGTGAAGCTCCTACTTTTTTTTTTCGACAGCCTGTAGAAAAAATATTGAGATTCGCAAAGAATTCACGGCTCCCCCTTTCAATGTTTACATACACATTACGAACGAGAAAACGAAAAAGCGAAACGAGAGAAAAGCATTGAGTGAAATGGAAAATGTGTTTTTACTTTTTATGAAAATTTAATCACATGGCGTAAGAGTGTCCCATTTCTGCTTGACGTAGATCTACAAAAAATGCACGTGGGTGAAGAGACGCCGAGTTTTCAACTGATTTCGCTTTTTTTTGGGCGAAAATTTTCGCATTGCTTGTAGATCAACTAGAAACGCAACAGTGGATAAGCGCGCTCTATCGACAAACCCGGTGTACTCGCGGACAACCAGTATAGTTTGAAATTTTATTTGAATTTTTGTTCGAAATTGAAATTGAAAAACGGTAGATGCCAAATTTAAATTTAAAAAATAACAATTTTTGGAATTTAATTTTTAAAAAAGTTCCCCGTAAATCTACACTTAAATCGTCTCGTAATTCGACAACGCTATTTTTTTCAATTGTTTTGCCCATCGCCAAACTTTTTTTGCCCAATCAAGCATCGTCAATTGATCCATTGATCTTCTTCTTCTTCTCTTTCTCTTTTCTCACCACCGAAAATTTTCATTTTATTTTTTGAGCACAATACTCACCTGTCTGCGTCTCTCTGTACCCCCGATCTCTCGCCTCTCAAGTATTACAAACGAAAAATTTGGGGAGAAGCCGTGATTTTCATTTTAGTAGGATATGAAAAATTCTAGTGAAAATGTCAATAAAAAAAACATTGTTTTTCAAAAAACAATCCCCTCGAAAATCCACACCAAATTCAATATTCACCTTATTACAAATTGATTATTTCTCCCAAAAAACACACGCCATCGGCCGCGCCAGGGCATCTATTGTCGCCTTTTTACTCCAAAAAATTTCTGCAACTGTCTGGCGTCACCGGTTAACACTGAGAAACAACAAATTTCATTTCTCGAATAACATTCATTTTGAAGGTTTTTGGTTACAAATTCGACACGGATTTCTGGCTTCCCTCATAATTTAAAATGGAAGAGTTTGCTGATGAACTAGGCCAACATGTCGGCCATATTTGGCATAGGTATTTACGGCGCGTTATGCGTGCCGCGTCCCTCGATTTTAGTTGTAAAAATGTGAAGTGTCCTCGTCGTGGAGTACACGACTTTCCCACGTGCCCGGTGAGAGATTATCAATGGCAATCATTCAATGAGGTAGGTCAGAACGCCTTCGAAGAAAATCGAGAAAAACATATCCACAACGATACTCCGCAAGGTGTGCGTGTTGTTAAATGATAAATTCAAAGCAAATAGCGATTTTGTTTCCAAAATATGCCGAAAAAAAGGAAAAAAAATAAAAATAAAAGTTCAGCAACTTATTTCTCGGCCGTGGTTGTGTCGTTGTTTATTTTTTTGCGATCGTATTTTTTCTAGAATAAGACTTAAAATGAAAAAACATGAATAAAAATCAGTTCTCCATGGCCACTGTCAAAAGTCGCAACGACACTCCCCTTCCAGCTCCCCCCCGCGTGTATTCTTAGCATGTGTAAATTACGCGATGTAGTGTATAAAACCCTAATTTTTTAGAAGATTTGAGAAAAAAAACTTTTAAAATATGGGATAAAATCTCCTTTCCCTTTTTTGAAATCAAGAACTATCCGACAAAAAGTTTAGCCAAAAGTCCAAATAAAACCAATATGTAGAAAAAATCAAAAACTCGGCCCTCCAAAAAACTAGGCTACACGTTGTTTCGACCTCGCCGTGCTCCCCACACCTATGCATATCGTTAAATGTCTCCCGGACCCCTCATTCCGTCACACATTTCTCAAAGTGTCTTTTTCTCAAATTCGCTGTCGAAAATCCCTGAACATATCTCTTCAGTGTTGAGAACGACCTGACAGTTTTATTTCGATTCTCATGATCTCAGTGTCTCCCGGATGACTCGAATTCCTTCGATATATTTTTCTTTGAAGTTTTCAAAATAATTTTTCCTATATATAGACTTGATTGTTCGGTGGGAATTTCTCATTTCAAAATATTTATTGAGGTCGCTTCCCTTTTTATATGGTCGTTAGGTTTCTAAAACTCGGCTTTCCAAGTTGTAGCTTAGAGCTCTTTGTCTCGGAGTATAAAAAATTCACAAAATAAATAAAAGTTCACGTGGCCGTGGCCTAGATTTCCAAACTCGGCCACCATTTTTTTCTCTGACAGTAATCCACTTAGATCTCCTTTTTAGCCATTTTTTAACTAAATTTCCCACATATTCGTCCGTGGCTCCATATCAATTTTACTGATAGTAATTTCCAATAAGGTATTTTCGGGAAGATAGGAACCCTTTTTCATCTAATTCGTTTGTTTCTACTTTATCGGTTTTGCCACTTTCCCGCATGCCTACGAGCCTACATATCTGCCGACCTAATACAGCTCGTAGGCAGACCTCGGCCGCCTTGTGGTGAGATGAGTCGCTTTGTAGGCAGGCGTAGTGTGTGTCTTGCTGGTATGAGTAGGGCCTGTCAGCCGCCCAGTAGGCAAGCGTAGGCATGCAGCCGTAGCAGGCTTCTTAACTAGGCATCTAGGCTGCCTTGTAAGCCGGCGCAGGTAAGTGAAGGTTTCCTCGTGGCTGGCATCCTTGCAGTCAGGCACAAGTCGTCGGCTTGAAGGCAGGAAGAACATGCCGCCTAGTAGGCATATTTTACTTATAGGCCCGAGGTATTAATGAGATCTAGGCTTGCGGGTTAGTCGGTTTGTAAGCTGTCGTAGGCTGCCCTGTAGGCAGATTGAACTCTCAAACCAAACAACACAAAAATTCCAATATTTTTTGTACCTTCTGATTTTGATCTCTGACTCACTTGATCTTACTTTATCAATCAAGAGTCATAACTTCCATTTTTAGGAATAAACAATTATCCTTCAATTCATTGACGTTAATCCCTTTCAATATTCATTCAATACACAATGAGACGAAAAACTCTTATCTTTTTTCACTCTATCACATGGTGCAAAATTATAGTTAGATTGAAAAAGCTCATTTTATCATTTGTCACTTTTCCACCACTCTCAACGTGCTTTTTTTTAAACACAAAACGTTTCCCGTCATTTTCTACAGTACTCCCGCATTTTCACATTTTCCAGGTGACACCTGAGATGGAGGCCGACGAGTTTCAACGTTCGTATTACGGTCCTCTCAACGACGGCTTCTGCCACGTCACGGCCGCGACACAAGACTTTTGAGCTGTTGGGACCGGTGAATAATATCTGGCTGATATGTGTATAAAGTGTAAGATAATTGGCAGCCCGATTGCATTTATTATTGCGACGGTGATCATGTGCAGTGGTGGATCGTTAGTTTTTTTTGACGTAAAAGATAGTATAAGCGTCTTTTTTTAGATCAACCGAAAAAGAAATATGGAAAAAACGACATTTAAAGATTTTTTAGAAATCAAAAAATGTATAAACTGTATGTTGCTTAGGGCCTCCATGGTAGACAGGCACGGTTTTAGGGCCTGACGTGCGCCTGCCTGAGACCCACGTGGAGTCAGAAAGTCCCATTTCGCTTTGATCTTCAAAAAATGCGGGAGAAGAGACGCAGATATCTCATCTATTTCTGCATGGTCATTTAAGCGCAGACGTCACAATTTTTCTAAAATAATCCCGCATTTTTCGCCACGTAGAAACCGCAAGGAGACAGCCTGACAGCTATTAAGCCAAAGGCAAAAGTGTTTGGCCGTCTGACTTTTGAAACAAAAGGCTCGGTGAAAATTGAAAAAAAGTCTAATAATAATTAATATAAAAGTAGAACTATTTTCAGTAAAGGCCAAATGATTGTTTTATAAAAAGACTTAATTTAATTAAGCCCAATTAGATCTCCTAAATGTTTCAAGCAGCACAACTTTGCATGTGACGTCAGGCTGTCTCATTACAGTTTACAGAAACCGCGGGAATTTTTGTGCTCCCAGGAAAATGTGCCATCAGCACACAATGCATAATCAGATGAGATTTCAGCGCCTCAACTCCCGCATTTTTTGTAGATCAATCTAAAACAAGACTCTCTGACACCACGTGAATTTTCCAACCATCAAACTATCAACAAATTCGCGCCAAAAAAACTTCTTTAAAAACTTATCATTCCCAGTGGGAACAATCGGTCTCGAACTGAGGGATAATCTGCGACGGGTACACGCCAAAAAACTTCCCGACTGGAAAATCGCCTTTATCGAGAGTTCCTGAGTTCCGAAGGTGATCCGGTGATGACTACAGTTCTCATCATGACTGCCAAAGACGGAGGATCCATGGATCGGACCAAGTATTTGGAAGTAGCGGGTGAGTGGCATAACATATCTGATACCGTATTTCCTCCATTAGTAAGGCATGCAAAACTGATTTTCGGACACCCAATTTGCTTGCAAAACTAATAGGTGCAAAATTTTCGAACAGGTTCTTTCTCATTAAGTTATATATTATCATCAATTTCAATATCAACTTCTTAGGAACCAAAATGCGCGAATGTTACGACTGATACGCAAAAATTGTCCGAGTGTACTCATATTTAGCCTTGACCTGTTATACTCAAGAGCCGTCTGTAAGAGTTTTCCTACAGAACGATTTAATAGTGCAAATTTTGAATCTAAACTTAGGGAACAAACTCGTTAAGGGGTGGAAAAATATTAGAGGTGCAAAACTAATAGAGAGTGGAAAACTAATTTTCGATTAGTGATTTTTGATGCAACTAATGGAGGTGCAAAACTAATTGAGGTGACTAACTAATAGAGGAAATCGACGGTATATTTTTTTGGAATAAAAAATTTCAGCAATGGCTACTGCTACATCTCCAAAAACCTATCCGCACGTGGCCGGTGGAAACGGCAAGTTCATGGAATTCGAGATTTCGTTGTGGCCACTACTGCCAAGCCATTGCAACGACATCATAGGATACCTGGACGCCTAGAAAACCAAGTCAGCTAACCCAAAAATTGATGGCTACCAACTCTATCACCGATTACCAGAGTAATGGGTTATCAGCTTCATCTCGAGCGATCCGGGGTTACTGTGAATCAGTCGGATCCGGTCACTAATATTCAGAGTATGAAGGTAGTTCTGACGCTTCCTGTGTTGTCAGAGGTACGGACGATAGAGGATATCGTACGGATAATCTGAACAAGTGGGAGCTGGCGGTTTATAACTATGCTACAGGATACTCTGCACTCCGGAGGGTGACGATCATTTGGTGGAGATTAATGTGAGTGGCGAGAATAAATTGGACCATAAATTGGGCCAGCCCTAAAAAGACAGCGGGCCGGCCCATACCGACCCACTTAAGGTCAATAAAGTTTAATTCAGGTGTGTGCCGCAAATTTTGACTAGAATTTGCTCGGCAAAATCGGCTTTGGTAATCGCATAATTTCTCGCTCGGCAAATTCGACAAGATTGAGATTTTGCCGTTTTCGGCAAACGGCGAATTTGGCAAATTTGCGCTTACACCCCTGGTTTAGGGGTTTCACCGTGTTTAATTTTCAAAGCTTATAAACCTCTTTTCCAGGTGATCGGAAGTCGTCGACACCGAAATGAACAAGGACGCTCAGAAAATGGTGCCCAGTCCTACTTCATTGTCGGAATCGTCTCGATGATCATCTTTATCTTCTGCACCGTATCGTCTCCCTCTGCCTGCTACAGCAGTTCTAACGGATACTTCTCCAGTCGATCGGACTCATCGCCCTCGCCTGCCTTTGCCGATTCTCGCAATTCTCACTGCATTCGGAATCAATAATATGCTGGGAAATCGAACGAACTCTCCGATGATGATCATTCCGTCCTTGATCAATGGAATCAGAGTCAACGATGCGTTTTTGACACCCAGTTCAATTGGTTGCAGCATAGCACCCGGATTTTCCGTCAGGGAAGCGGTTGGCGTATCTGTTGGCTGAAGCTGGTCCATCGACGACTCACTACGACCACTTTGACAAATCTAATTGTATTTTTGATCGGGTGTATGAACCCAACGGAGGGAAAGGTGTGGTGGACGGCAAACTACTTTTTCCGGCAGCGTTAATCGGTAAATAGGTAAATTGCCGGAATTGAAATTTCTGGCATATCGAACCGGCAATTTGTCGATTTGCCGAATTTGCCGGATAGCGAATAAAAAATTGCCCAACAGCACCTGCGCCCTGTTAAGGAGCTTTGGCCTCTAACATAAATTTGTCTATTCATCCTTAATTCCCTCGTAAAACGACAAGATGTATTCCAGGGATGACGATCTTCTGCCTTGTGCAATCTCCCTACTCCTCGCCGTCTACACCCTCACGTTCTTCTGTCCGGTGCTAGTTCTTCTGCTTAGCGAACGCGTCAATACACGAGCCCAGCTGGAAGCTCGAGGGCACTTTCAGGTTCTCGGATTCTACAAAAATCATATGCAGCCGATGGACATTTGCACTTCTCATCATCGGAAGTCTTGTCTAGTGGGGTTTCCGTATCTATGGAACACTGGGGATCCGCGCCGGTGTTGAACACTGCAAAGATCCTTCCCCTGGAGACGCCGATCCGACCGAACTATCGAGGAGACCGTGTGAAAGCGTTAGGTCAACCCAGTCACCGTGATTGAGAACAGCCAAGTTGATATAGGCAATGCAAAGGCTTCGAGCATTTGACAACCTCGTTGCCATCGACTTCTATGCAAAAGTGCCGGGGATCCGAGTACACCATATCTCCAATCAGAGACTCTACCATCAGATCTTACGGTGGAGGAGCCGTGGACTTTGATTATGAGGAAGAAAGCGTGAAAAACACTTCACATTCCCCTTTAGACTCCAGTAAGATAGCCGTCCACGCGTTCCTATTAAAATCTACATATATGCCTATAACGTGGTTATAGAAGAAAAATAAAACGCCATAACCTTCTGCCGCGCAAATGAATCCGCGGGAAGAGACAAAACTACTGTAGTTTTTAACCAATTTGTGTAGGCATTTACGAGCTATTGCGTCATCGGTTGTATTTAATTTTGACAATTACTTTTAATTTTCAGCGTTTCACTCGTTTTTATATTGAAATCTTTTGTCGGTATTGAATAAATCTTAAAAGAAAACACAAAAAAATTAGAAAAATTCCGAAAAAAGCCTGAAAATTAAAAATTGCGGCTTACAAACTTAAAGTCAACGATGACGCAACTAAAAGCTCGTAAATCTACACAAATTGGTTAGAAACTACAGTAGTCTCTTCCCGAGGTTTCATTTGCGCGGATGGCGATTTTTCTCATGGATCACACACGTAATCGGCACCTACATATTTTGTGTGCCTAAAAACACGGTCATCCTAGCAGTGAAAGCAGACAAATGTAAGCACTTAACAAACGTGAGTAGGGCTTAAATGGTATGCACTGTTTTAGGGCCGCCTGTCCAGGCCTGTCTTGTACGTTTCAGCAATTCAAGCCGTATCTTTCCAGAGAGCTAGTGTCACCCATTGCCAGCTAACCCTATCTACAAGCATCACAAGGGAGGACTAAAACTTAACTTTTCAAATCCGTTAGTTTCAATCTGCCAGCCCCCTGACCCTAAATCGAGTCTACCATTTTCAGTGATCCAATCCGAAAAGTACAACTGATATCCGCGCTTTTATGAAAACGTAACCTTGTGGGATGAACGGATTTATGCAGGACTGGCGGACCAATAATCGCAAGTTCCCACGTGGCCCTAAATGTTTCAGTGTGGTTCTAATGTGAACGCAATGTGTCGTAGATCAGATGCTGAGTCTGGTTGGCGATCACGGTAAGATCTCAATGGTTCCAGCGCCCTATAAATACCGCTTATTCTTTCAGAATGCCCTAGTCACCTTGGGATGTATGGCTGCCTTCTGGGTAGTCTTCATCCGCAACCCCCTCTCAGTTGGCCTAGCGACCGCTTCGATTTTATCCATCTCCAAGTAACTGGATACCGGTGCTTCTGGGACTTGGATCTGGACCCTGTGACCCTCTGCGCAGTAATTTTTTCTTGGATGTCCGTTTATGAGACTTTGTTGCCCATGTGGACTCCTGTCTCTATCAGGTCAGGTATGAAGATTTCGAGGAGAAAGGAGTATTGAAGAGGATTGAGATGAAAACTCCCGAATCTTGAGTCGTCAACTCGCTGTCCAATTTGTGTTCCCTGGCCAATGGTCCAGTCGGCGTCTTCAACTCGTCTATGTGTCCTCCACCTTGGTATTCTACTGGTACCTACGAATACCTATACTTTACCGATAACCCTACCCCTCAAACCTTCCGGAACTATCTCCCAATGGTATTCGTGAAAACCATCCTGCTTACGTCGTGATTTGGACTGGGGAATGTTCCACGGTCTCGCGCTGCTCCCGTGCTCAATTCCTGGATTTTCCCCTGTCAGTGTTCAACCAGACGTTCGCCGACTTGTTGTTCGGCAGAACATCCTCTCTCGTCTTGCTCTTCGGATTCCGGAAACCGACACTGGTGATGCTCAGGAGATGGTACCGCTCGCTGGAACCGAGAAGCCTTAAGACCTGAAATTAGTTGTTGTTTGTTATTATGTACAGTTGGGATACAAAGTGTATTATGTAGTCTGTAGTGTCGCAGTGATAGAAACTACAAATTCAAAGCTACAAACTATAAGCTTTGAGATCTGGCAGAGCTTTATAGTTTGTAGTTTTATTGTAGCAGCTACAAACTACAAATTTCTTTTGATGGCGCACAAACTACAATGTACATTTTGCCAGTTTTCTAGATTTTTTCACTCACACACACACACACACACCGTTTTGCTACGTGGCTGCGAAAATGCAAAACTCGGCCAGGTCGCAAACATCGCCAGAAACTTCTAGCTTTACCAGTAGCTTTTCATGATCTAGTCTTCTTTTTTTTCCCCCCTCAATTTATATTTTTCTCGAAATTTCAGAACGGTTCCCTAGTCTTCTGTCACCGTGTCCTGCCCTCCCGCAAGCGGGTCCCCTTTTCCCCCCACAGATCGTACGGCTTCTCAGGGTTCCTATAGCACTTTTTTCTTCGATTCGTGCCATACAAAAAATTATACTTCCCATCGCACGCCGTGTCCATTTTGTCTTGTACTTTTTAAATGCATTTTTTGATAAATTTGATTTTTTATATCATCCAGAAAAGGGGCAAAAATTCAGATTTTCCTGGCGAGTAATTTTGCTGGAATTTTTTCAAGCATCAGACATGCAAAAACTAAAACGACACAACACTATCGATGGGGATTCGACTCGTTCACCCCAGTCATCCTAACTATTTTTCACTATTTTTTTTAACTTCTGTTTTTTTGGTACTTTTCTGGCCGTTTTTATGAAATTTTTTAGCCCGACATAGTTTACCTTTTTTTGTTCTGGATTTTAGGAGTTTCTGCGACCTTACTCTCACTCATGTTCGTCCTCCAGCCCCGCCTAAGCCTATGCCTTAACTCAAGCCTAAGCCTAAGCCTAAGCCTAACCTAAATCGCGTCAGAGAGAGCGTAACGCTCGCCACTGACGCCAAGCCTCAACCTAAGCCTAAGACTAAGCCTAACTCTAAGGCTAAGTATAAGTAAATCTAGGCCTCGGCCTAATACTAAGCCTTAGCCTAAGCCTAAACCCAAGCTATCAGAAGACACTCAAAAAATGTTCAGATCATTAAAAAATAACTACATTCAACAGTTTTCTTCAAAATTTAGCTTTCGACTTTCCAAGTAATCAATAACATGATTCCAAAATCTTCATACATCCCTCCCCTCTTCACATCGTTCCCGACAGCTTGTACTATTTCTCCTCCACCCACTAGGCAAGGTCTGCGTCTCTCGGGTTTCATACGCTATCTCCCTTTTGTGGAATCAGTTCATCGTTTCGGATCGTGGCTTACTTCTCAATATCCGCGGGCGTCGCTTTACTTTGATATAAAGTTCAGTTTTTTGAGGCCAAAATTTAATTGGTGGAATCACAGCGTTTGGCGATGAATTAATTATCGTGTGTATTCAACTTTAATATACGTGTACATTTTACCGATGCATGTAAGTTTTGGTGTATCAAAAAATGCCCCTAATAAATTTCTTAAGGGTGGAGGAGCGCTAGTGGGGAAATTGCGAAGTTTTATAACATGCCTATAGTACCACAATGACCGAATATCATGATAAAAAAATTCAAAAAATTTTTAAAATTTTATATGATTTTTTTTAGAGGAAATTGGAAAAATCTCAGTTTTTACACTGCCTAATTCCAATTTGACTTACCGGTAATTTTGTTCGATGGAGCGCGCTTGCACGTTTTAAAATTTATTTTATTTTTTGTTATTTTCCTTTTTAATGTTTTCGGTGTATTTTTGCTCTAATTTTAGAGAGTCAAGATGAATGCAGATTTTACGATTAAAAAGCACGCTCACAGGCGTAAAAATGACAGAGCAACGATTTTAAACGGTATCGAACCTCATCTATATTAATTAATATCACAGATTTACGACTGGTGCTTTTTAATCGAAAATTTGCATTCATCTTGACTTTTTCTAAAATTCGAGCAAAAATACACCGAAAACATTAAAAATTGGTGGAAAATAACAAAAAATAAAATAAATAAATTTAAAAACGTACAAGCCCACTCCATCGAACAAATTCGATAATGTGATTCAAACTGAGAACTAGGCAAAAACTGAGATTTTTCCATATTTCGAAAAATCATATAAAATTTAGAATCTTTTAAAGAATTTTTTTATCATGATATTCAGTCATTGTAGTACTATAGGCATGTTTTAAGAGCCAGCAACCCACTGGCGCTACGCCTCCTAAAGTTTGGAGTTTTAGTAAAAAAAGATCGGTTTTTTAGTTAATAATATTAATATCCAGTCGCTCCTCCGGAACAGTTCGACCATTTTTCACCACTCTTCCAGAAGTACGTGGAAGAAATGTTCCTATTATGAGATTATTCGAGAACTATGCTGCATCGTGGCCGACCAAAAAGTCTCTTAAAAAGGACTTTTTGATCAGCTGGCAAATGTCGGTTCCCGCAAAAAGTCGTATTTCGTGCAAAACCGGCAAAAGCAAACATTTTGATTACCGGCAATTGTCGGAGTTGCCGATTGCCGGAAATTTGCGGAAAGAATGGTCGTTTGATACTCTTTTTTAGATTGCCTAAAAATGCATTTTAATGAACAATTTTTAATTTTCAAGCTCAAAATGATTTAATGCTTTAAGGATTGTCCGTTTTCTTTAAAAAAGACTAACCGAAAACTATAAAAAAAGGTGAAATTTTTTCAATTTCCAAAATATAATTAATTTTGGCAGCCGATTGCCGGAAATTGCCGATTACCTTACAATACGGGACGGCAATTGCCGAAATTGCCGATTGCCGGAAATTTCCAAAAGTAATTGCCGGATTTGACGATCGCCGGAAATTCCCTATTGCGCTCCCTTGTATTAAAGGATACGGCAAACGATGTTTTCCCGCAAGCGTATCGGCAATTGCCGAAATAAAATATTAATTCGGTGCTCAAACGGCAAACGGCAGTTATAACAGCAACAAGCCACTTCTCCAATTTATAATCGGCAATTTCGGCGATAAACGGTCAATTTGCAAGAAATCAAAATTGTGATCTTGCACATTTTTTCTGGAAATTTCAGAATTTCAATTTTAAACAACAACATGGTACCCTATGAACATATCTTAAAAAACCCGGAGTGAATTCTATAAAAACTACCTAGAGAAACTGACCAAATACTTAAAAAAGGGACGGATTCATGTGATTTTGATTAAGATAAGTCTTTGAAAACTTTCGGAAAATTGAAATCCGGCAAATCGGCAAATCGGCAACTTGCCGATTTCCCGAAATGGCCGCAGCAATGAACTACACTGTTCCAAATCGAATTCGTAACCGATATTATACTTAGGGATATTTGTAACTCGTATAAATATTAAATAATATATATATATTCCAGCTGCTCCAATCTCTCCAAATGGATGCAGTAGCCACAGGCTACAACTCCCTATTATTCTCAATGGCTGATATGCAAATCGAAAAGGTCATGGGTAAATGGATAGACATTTGTTTATTCGAAAGAATAAAGAGGATTGTTCAATCTTCTATTGTTAGTTTATTTTCATTCTGAAAATGAGATGCAATTTTCAGTCGATATGGTACTTCGAACTCTATACACCGCAACATTCACCTCAAAGCAGGTCGGAGTGATTAATAATGATGTCGTCACCAATGTGGAGTACGGTAGTATGGTTGGTCGAGAGCCCGCAGCCGTTCTCAACGTAGTGTAAGGGATCAGTCTCCATGTAAGTATTTTAAATATCTTTGGTCCGGTGATGATTAAGATACAAGTTTAAATAGTTCCCGTTTCAAAACTTCGGCTAATTTCCCGCCAAAACTTTTCTCTGAAAAATTTTAATTACTTTCCAAATTTTTTTCTTTGAAAATTTGGACTACCCGCCAAAATTTTGTAGTAAAAAAATTGAATTTCTTTCATGGCTCCAAGAATGTTTTCTCAGAAAATTTGAATTTCCCCGACCGCCAAATTGTTACTGTCAGAAATTTTGAATTCGATTTCTCGCCAAAATTTATTTTCTGGAAATTTGGATGTCCCAAAATTTTTTTCTCAATAAATTTAAATTTCCCGCCAAAATTTTCTGAAGATCTAATTTAGCGGATATTCTTTCCAAATTTTTTTCATTGAAAATTTATTGAATTTCCCGCTAAGACGAATTTTATTGTCAAAAAATTTGAATTTCTCACCAAGACTGTTATCTCAGAAAATTAGAATTTCCCGCCAAATTGATACAGAATATTCTAATTTCTCGCCTAAATTTATAAATTACTGAAAATTTGGATTTCCCGCCAAAATTTTGTTCTCAATAAATTTAAAATCTATCTCCCGCCAAAATTTTGTTCAAAAAATTTGGAATGCTCGCCAAAATTTTATTGTCAGAAGAAACTTAAATTTCTCGCCAAACGCAGGTCTTTTCCAAAATTTAATTCCTGTCAAAACTTTGTAATCAAAAAATTTGAATTTCCCGCCAATTTTTATTCTCCGAAAATTAAGAAGGATTTCCCGCCAAAACTTTGTTCTAAAAATTTGAATCTCCTTTGTCGCCGAAATTTTATTGTCAGAAAATTTGAATTTCGAAATCTCTATGAATAAAACATTGGCAGTGTTCCCTGTACGAATCGGTGGCTTGAGTGACGAAGGAGAATATCAATACATGATCTTAAGTACACCCACTGTAAGTATCCAACGATGCTCTTGACAGGCTAAGATTGCCTTAAAATTTGTTTTCTAATTATTCCAATCTAATCTTCATGTGATGTTGCGAAAAATGCAAACATGTATTTTAATACATTTTCCCCCTATTGATGGCGTCGAAAAATGTAGAAAAATGGAATCATTTTTGTGCATGTACATTTTCGACATTTTTGACATTTTCCGACATTTTTCGACGTTATTAGACATTTTCACGCATTTGACCGAACTAGGCAATTTTGGGTCCGTCTGGGGTAGATTTAAGGAGCGGCGCGTTGCGTGTCGCGTCGCGGCTTGATTTTAGTTGTATAACTAAATGTAATTGCTCCGTGTGGAGTACACGACTTTCCCAGGCAATTGTCAATGGAGCGCGAAAAATGCAATGAGGAAGGACAGAACCCCGTATCCACAGAAAGAATTTTCTCTGCGTCTCTTGTCTTTAGCATTTAAACTGGGGCGAGATGTAGAAAAATGCTGAAAAATTTCGAATTGAAAAATAAAATGATGGCAATGTTACATTTTTCTGCAGTAATTGCGGTACGCAAAAAGCATCACATGGATAACCCCATAAAAACTCCCATTTTTCCAGAGACCTAACACTATTCGAAAGGAAATGGAAGCGTGTATGATGATTTGTTGAGAAGAATGGTTTTATAAGCGCAAGTCCAATGGCAGCACTGAACACTCGTCTGCATTTTTGCACAGATGTCTATGTTTGCAGAAAAGTGAATAATTTATATGAGAATGGAAATGTTTGAGTTGAAGATTATCTCTTTTCTGAGGATACGGGAGAGTTCAAGTTTGACGGGTTGTGCAGTGTTTACATTTCTAACCTTCATGTGTTAAAAATAAAGATTAATGATTAATTGGATCTGTATTTAAAATGAACTTTTAAAACACAAAATTTCAGATCTTGGTTTAAAAACGTATACACTTGAAACTTTGTTGAGTGTAATGACGTAATTTGAATTTCGCGAAAAAATGACTGTGATATGATTTTGACCGTGTACACGGGCAATAATATTTTAATATTATGGATTATAAGCGTTTTTCAGTAGACTTTCCATATTTTCTCATGATTATTACTTTTATGACCCAAGAAAAGCATTGTTTGGAACTCAAAATTATCAACTTTAAATGTTTAAAAAAATTCAGGAAAACATAATATTTGCGTATTAAAAAATTTCCCAGTAATTTACCACAAAAAAGTTTCTTTTTCTTTTTTTAATTTTTTCTCAGAAAAATCAAATCTCCCTACAAAGTTTTTCTCAGAAATTTTGAATCCACCGCCAAAAATTTTTCTCAAAAAATATGATTTCCCACCAAAAAAATTTTTCTCGGCACAGAAAATTTAATAACAATTTCCCACCAAAAATATAGTCTCAAACTAGAAATACTAAGAGCATTTTCCCGCCAAACCACTACTTTTTTTAAAAGAAGATTTGAATATACCGCCGAAAATTACTTACCAGAAAATTTCAATTTCCCGCCAAAAATGTTTTCTCAGAGAAATTTTTAATTTTTGGTCAAAATTAAAATACTACTACGGTACCTTAATCTTACACCTCCACCGAAAAAATCATTTTTCAAAAACTACTACAGTACTAACAGTACTCCTACCGTACTGCTAAAGTACTCCTACCGTACTCCTACAGTACTCCGGCAACCGTACTCCTCTACAGTATCACTACAGTTTACTCAAACCATATCACTAACACCAATCCAATATCCCGTCACACGACGATAACTTTTTTATTCAAAAATACAGTAATCTTACTGTAGACAATCTTTTAAAGTCTGCATCCAAAACTATATCGGATCCCAAAAGTAAACGACAGTCAGAAAATTTGTATTGGATTTCGCGTAGTTTGCTCTTCCGTGAAGGCAACACACGTAGCTATATTGATGCGATGAAAAACGAGAGGAATCAGTCGAGGTGTCTGATCTACTTCCAGGAGACCGCTCTTCGACTCCTATTGGCTCTTGCAGCCACCTCATTGGCGGCTCTTCCAGATTTGGGATATCCCGGATGGCAGTGCGATGCATCGCTTTACCATCCGAAGTAGCTTACTTTAATTACTAAATTTTGAAAGATTTTTCCTCGCTTCCATGAGCAAAACTACCCCGACTTCTGCCCACTCCGTCCGACTCACCGACATAAAAGTTTTGGGAGGAGCTCTCGTTTGGAGACTCCTTGTCCGCCGCCAATGGAGCCGGAGCACCAAAGGGAGAACCCTCTGGCTGTGATCCTTCCGTCAGTACAGAGCACTAGCCTTCCAGTGTGGAGCGTGGTGACCAATCTCTCGACGAGCATGTCACTGTTGAAAGTAAGCCATTTTTCTGAAAGCGGGAATTGGGAAAAGTGAGTTGTTGCTAGATGTACTGAAAAAGTTCCTAACCTAATGGGATACTCCACTGGAACTAGTTCGGAAGCGCCAACGTTTGGGAGGTCTCAAACCGAACCAAGCAGTTCCAGGAACTGAAGCAATCGATACCATCACTTAGATGCTGCCAGAGCTCTGGTGCAGATTATCCAAAGCCACGAGGAGGTGATCTAGCAAAGTCCAAACTAAACATCAATTCCGATGCATTTCCAGATTAAAGATTACAAAACTGATTGGAAGTTTACGTATTCATTGGAGCAAACGACATGTGCGCCTATTGCAACGACCGAGAAAATGTAAGATAGTCAACGATCATTCCACACCCGGTTTTATTGCATTTCTATAGGGCCTCAAAAGCAATCTGCAAAATGTCACTGCCATTCAAATTTTAAAAGATAACTTACCAAGGTAGGTAAACTATAGGAACATAACATTATAACAAGTAAATAACTATAATATTATGAAATTGTCACATACCTATACCTACGTATAAATACCTAAGTAAGGGTCCAGAGCGGTGTGGCAAAAATTTTGAAACCAGCAATTCGGCAAATTTTCCGGGGTCGGCATACTTGGTAAAGGGATCGCAACATTTTTTGGAGCTCAAAAAGTGCCAAAATTAACAGAAAATCTAAGTTGTTAAACATTTGTGGCAAATTCCAAATTTGTCTAAATTTTTGAAATATGCCTTGCTCGGTCAAAGGTATTTCCGCAAATTTGCCGTGGTTGTCCTCGGTAAAGCGCATCATTTTTTGGTGCTCAAGAGTACTGAGTTGATGGAAAAGCACTTGTTTCAGGAAACATTTGTGCGAATTACAAATTAAGTCCAAATTATTGAAATTTCCTTGCTCGGAACCCGGAGACCAAATTCGGGAAATTTGGCACACCCTTGATCCCATAGCAGTGGCGCAAAAAAATCTTTAAAAATAGCTTGTGGCCGTTTCCGTGCCAATTATAAATTAAAGTTAAACATATTATCGAAAAAATACGATTGCAAATTTTTGGCACTCGTAACTTTGGACAATCTACCTTACCTGTTGACTAGGCTCCTCCCCTTCCTTCGACAAGACCCAAAATAACAACGGCAAAAAGATTATGGGCAACGTGGTGCCAGGCTGTCCCATTCCAATGTTTGATCTAAAATAAGGTGGGAATTTTTCGCCCAAAAAAAAAGTGACATCGGCACGTTCTTACCATATTGCCAGTAAAAGTACTCTGCGTCTCTTCTCCCGCATTTTTTGTAGACCAGCGTAATTGAAGCCAAAATGAGACACTCTGACACCACGTGGGCGGAGTCAACTTCCACAGGTAGAACAAAAATTAATGATGAAAAAAGATTTGCGATCGGATTTTTCGATAATAAGAGCCAACATTTTCGGCTTTTTATGGAAATTTTTTTTTCAAAAAGAGGTACTCAGTACTGATGGTCCATAACTATGCCATCAATACCAAGTCCTTCCAGAACCATCGTATCGATGCCCGAAATGATCGACATGGCCATGATTCGCGAAATCGACCACCACAAGTATTTCTGCGACGGATGTGTACGAGTGATGCGAGAAGAACAAGGACTTCCCGAATACCGACAACTCGGCTGGCTGCCATGTTTACATGGATGCTCAGCAGGAGATTCAAGCCTCGGGCGAGTAATCTTCGACTCAACAGTTGACTTTACATTTGTCGTCCGATTCAACCATTCTTCAATGGAATCACAGTTCCACGACCGCCTCAAGACCGTCGGAGAAGTCAATCTGGATTGGTTTGCAACGGATTGATTCCATTTCTCAAAACTAGGCCACGCCAATGTTGGCAAGCACGTTGTGGAACAATTCAACCAGTCGGATCCAAGAACCATCAAGTCATGTCAGATCCTACCATTCCACTAAACTGCCCAGACACCAAGTGCCCTCTGTACAACTAAGAGTTGACTGCTCGAAATATAGGACTGCCTAGACTGTAGGAAATTGAGTTTGTGTGTGTAATTTGACGTACTTATCGGGTCTGCAATAAAATGTTTTAGTAATCTTTAATTTTTAACGTGTGAGACATAAAAGAGTACCCTCAATAAAAATATCCTCGTGGACACAATATAGTTATCCCAATAGAGTCAATCTAATTTTTGCAATTATTATTTATTAAGAATGGATATCAAGGTAAAGGAAGGGATCTAGATTTTGTAAAAAAGATACTGGAAATACGAATTGTTACGGGATTTCATAGAAGGGGATATATCACGACTTTTTCTTTGAAAAAACAACATAAAATGATTGCGGCTTCACAATCTGATCATCCGGTATTTCTCCAGATCCCTTTTCCGATTCGATCTTACTTGATACGCCGGTTTTGGACCTACCAGATTTTCATCTGGAAGAAATTTCAGCTATGCGTTGAGTGCAGCGTTACGCGTTGCGTGCTGCGTTTACCGCGTTGCGTGCCGCGTTGCGTGCTGCGGCGGGCTTCGTTGTCTCGTGCCGCGTTGCGTGCTTGTCCGCGCTGCGTGCCTACCTTGCGTCTCCGTGACATCCAATCGTTTTGCAGCTCACTTGTCTCACTACTTGACAAATTTTCGCCTCAAACTGCTTCTCCAGTTCGAATACTTGTTTCCCGGAAAATGAGCATCGTCCGCGCTCTTTCTTCTTTCTCTTTGTTTTTTGACAGTTTTCTACAGGAGACTTTTTGGCTTGGTCGAGGCTGGATTCTGAAAAAATATTCTCCTAACGGCTGATTAGTTTTCTACGTGTAGCATTTTACTGTCGTCGAAATTCATTGAACAACCCTGTTAGTAAATTTCCAAAAAATTTTTTTCATAATTTCGAAAACTGCGTATTTTAAATTTTTTCACATTTTCTAATATTTTAAAACAAAATTGAGAGTAAAGGAAAATTGTGTCTTGTAATTTTTGTAATTTTTACTCAAAAAAAGGCCAGTGAAGTACTATTACAGAAAATACGAATCGATAGCGCAGTCAAAACTAGAGAACATCAGTATTTCACCTCAAATGCACCATGCCCAAAACTAGTCTATTTTTCAACTGCAACACTTCATACACCTAATCAAAAGAAATCAACTTACTGATCTTCCAAATTCATCAATTTCTCCATTAAAAGAGACATAGGTAAGTCAAGTATATCCTTTATCAGGTGACTAGTTATTCTCTGCGGCTTCACATCAGACGTCAACAGGGCTCCTTAAAATAGCAGGTTGAAGTAGTTAGAAGAGCAAGTCAGTTTCCATTTTGCACGACTGAAAAGAACTTCTGAGAGACTTCTCAGTACGTCTCGAGGTCCCCGCCTCCTCTTCAATCAAACAATTGTAAATTCTGGACTCACGGGGGACTTTTGAAGGTTGACGACGACGACAATTTGCCCAAGTGCGACAATCATTGCGCAATTGGTGTGCAAAGAAGAAGATGGGAGATATGAGTTCTGAGATGATGACAAAAGCATGAGAGCACAATGAATAAAATGAGACCGGATTTCGAGAAGGAGGAGGGGGAGAGGAGGATTGGTGGTAAGGGCTGATACTTGATGCAATTGAGGGAATGCGTTTCTCATACTTGACTATTTAATACTTTTCTTGAACCTTAATTATTTGGATTGTAATTTTGTAGCGGAGGCACATGTGATATTATTGTGCTAACTTGGGTAATCCTTAGACTTTCAAATATAACCTTCATTATTTGAAAAAAACTTTTTGAATAGACCTGCAAGGTTGATCTACAATTTTTCATGGAAATCGAATTAATTTTGTAAGGATGTCTACTGAGTATAAGCTTATCGTTAGGCTTAGGCTGAGGTCTAGACTTAAGGCTACACTTAAATTTACTCAGGATCGCCCTAGGCTTCGGCTTCGGCTTAGGCTTAGGCTGAGGCTTATGCTGAGGCTTAGGATTATTCTCAGACTTACGCTTAGGCTTACGCTTAGGCTTAGGCTTAGGCTAAGGTGTTGGCAGCTTAGAATAAGCTCAGGCGGGGGTGACCGCGGGTAGAAAAAAAAGGAGAAACTTCCAGAAATTCACAAAATTCAGAAACATACCTTTCATAAGTTTATTTTTTTACTAAAAAATTACTCTTAAAATGTATGCGAGAAACCCGCATGCAAAAACACCTTTTTTTTTTTGAGCAATTTCTACCTTTTTTTTATTTAATTTAAAAATACACTAAAAAAACCAAAAAAATTTTCCGAGCCCAAATTGCTCCCAAATGCTCTAAATTTCTTTTGAAGTCTGATATATTCCTATTAGAACTTGAGGAAAATGTAAACCTAGAGAAACAATACTACGCATGTTAAATGTAAATTATTAGTTTTAAAAAGTCGTACGTTATTTTGGAAAGTTTGAGGTTTTTGCATTTTTTCCGTATATCACTGAACACTTTTATTTAAATATCATCAATTATCGGAAGTAGGTTGCAGGAGAAAAAATATATTCTAGCGGGGTAAATTGAAATGAGACGGGGATCATTTAACTAAAATCGAAAGTTAATAGTTGGTGATCTACAAAAATTCTTAAGACAGTATAAATTCACGACTTCCATCTTGGGAACATTCTTAAAAAATGTCAACGAATAAAAATCTGACATTGTGGCAAACAAACTTCTAAATGTTTCAGACCTTATATAGCGGACATGACAGTGGCTTGCTTATTTGATATGACTTGAGTTTATTTTTTTTTTATTTCAAGCGTGGGGAGATTTATTTGCCTAGATATATATATAATTATTACTGGAACGAACTGGAAAATAACTTGGGATCAAAATCAAAAATTCAAACCTTCAATAGAGATTCAATCTTTTCGAAACTTTTTCTATAGCTTTGTCGAGAACCAACAGACCACGTAAATACTTATAGCTAAAATTTTATTAAGATTCTAAGTCATGGTGAATCGAGAGTTTGTCAAGTTCCATGTGGTTCCTAAAAATAAACCGATACACGTGGTGTCAGGCTGTCTCATTGCGGTTTGATCTACGAAAAATGCGGGAATATTTTTCCAGAAAAATTGTGACGTCAGCAAAAATAAATAAGGGTCTAACCACAAAACTGGTACTTGAATCTTGAATATTTTTAATTCACCCTAAATTACATTCCCCTGATTCCGAATATCTATGATGACTGAAAAAATTCAAATACAAAAATTTCCTGACAAAGATTTATATTTAAGCTAAATCTTTCATCAAATTTTTTTTTTAAAAATTTCATGTACTCGCATCACTTTTTTCAAACTGGCGCCCAAATAAATTAGCGCGCGCGTGCATCGTTTGACCTTTTTTTCGTTTTTTTTATTTCTAGCCGAATTCAATTTTTTTAAAACCAGTTTCAGTCATTTTTGTCGGTTTTTTTTTCTGAAAAAAATGTAAAAAAACGACAAAAAATCAAACAATGCATTAACAGCGCGCTCCAATGCTAATTTATTTGAGCGCGTATTTAACAAAGAAAGAGACCGGGATACAAATGAATAATCATTCGGCGATCTCAAGCTTAAATACATGGAAAACTTGTTTTGAATTTTTAATCTTTTCACATACATACTCGGAATCAGGGGAAAATTAGGATTCATTCAAAAATATTTCCCAGATTTCACTCGGTACCCCACCTTTAAAATTTTTACATGTTTTGGGAAAACAAGGGAAATTTCTAGAACCTATTTTATGCCAATACCTAAAATGCTGAACATAGATAAAACACACACACCCGTATGAGTATTATATACTTCCAATGAAACATTTGAAAAATAAAGAGTTCTCAGCTTTGATCATCCACTTGTGATATTCTCACGCGTAATAGCACATGGCACCAGCTCAAAGTGCTCATTTTGGCTATATATGAAGGTATATGAAAAAGTGGAAATTGGGAGGAAAAATGGCATGTTGACTTCTCTACGTGGCCTATGTGTGAAAAAACCCTTCTATGACAAATTCAGTTTAATTTTTTAATTTTTCTTTTTAAAATTCTAAAAATGGCTAAACGTTCAAAAATTTTTTAAAAGCCAAATACTATTAAATTTCTTTGTTGATTTCTTAACCCAAATTTACGATTTCAGTCAAATTTTTGAAAATTACAAAAAATTTAAAATACAGCTACTTGTAAGATGCGCAAAACAAGAATTACAGAGTTTTCAAACTATACAACAGACAACTCTAGTGGCTGAAAACTTCCAAAGTTAAATAAAAATTCCAAAAAATCGATAAAAAAATGTATCTCGAAAAATTACCGCTATAAGAAAATGGCCTTCTCTATCCCAATGAAATTATGGAAATAGATTTTTTCAAAAGCGATCTAGTTGGACGCTGTGCAGGGAAAAAAAGTTCAAGCGCGCAAAACTTTCGCTAGAAACTCAAATTTGCCTCATCAGACCTTGTTGGATTTTTTTCCCAAAGAATTTTCAAATGCCGAATACCGAAACTCCAGGGCTCACGTTTAGACCTTAACATGAAACTTTTGCCATTTGAACGAGGCTCTTTGAATCTCTGTAAAAGACTTAGCGGCAGACGAGCACTTTGAACTACAAAAATGTCGCTAAATTGCTATCATGGAAATTTTTCACTACTATAGGAGCCCGGTAAAATTGCTCCAAATCATAATTTAAAATATTTCTTCATGATTTTTTTTTGATTTTTTCATGATTTTCGAGGTAGGAGCAAATATTCAGTTTATAGGATATATTTTTTTTGGAAAAAAAAATCTGAAAAAACCCACATATCCAATAAAAAAATTACCAAAAAGCTTTCAGAATACTTGTCTACCTCGAAATATCGTAAAATTCATACAATCTCTGTTCAAATAAAAATATAATTTGGAGCAAATTAATGGGCAATTTCAAAGTCTAAAGTAGTGAGCTATAATGCATACATTCCAGAAAATGGAATAAAAAATAAACTGAAGTCAAGTTAATCTAATCTCAAGTTACCTCCTCCTCCTTCCCCCAACAAATACTGCTCAATAGCCCCCAACCAACTCGTTCCAATTTGAATAGTGTATTATTTAACAAGCTCTGTCATATCTCTCTCCTATTTTTTTTTTTAAGTCATTTTTATCGTCGCACCCCTCGACCGTTGTTGTATTAGCCTCTCTTCCTTCTTCTTCTTCTTCATGAAAACGAATTAAATTTCTTCATCCAATTCACTCAAATCACATCCTCCACCGACACATTCAATTAATCAACCGGTCCTTAATTGAACACAACAACAATCACTATTTCATAAAAATTAGTGTTTTTAAATGTACATTCAAAAATTGCGACGGCTGGAAGAATTATTATTTACACCAGAAGAGTAAAATTTGTAACCATAGTTATGGTAGCTACGGTAACTCAAAAAATTAGGGCATAATTATGCGACATGTTCTCATGAGTGCGCAATAAAAATAAAGCTGATCCAATACTCTTGAAATACTCCAATAATCGTTTCTGATTCCGGGATTCCTTCTCAGACAAATGGAGCTCGGAGTGCTCAATTGGTCAATGTCGCTGTCATGGCACCAGGGTTGTGCGGCATGGATTTTTTGGCAATCGGAAATTGCCATTTGCCGTTGGAAACTCTCGGATTATTTTTTTTCGGCGATCGGCATTTGACGGTTGCCGAACATAAACTCGTTTTTTCGTTTATTCGCTTCCGCATTGTTCGGCCGACAGTGCTTAATCTCCTTGAGGTAATTTTTTTTTATATTTTCTTGTATTTTATAAACAGTCTAAATAATTCAATTCCAATGATAAGGAGTGTCTTGGTTTAAATTTTCTAGCACAGATAATTTCATTTATTAACGATCAGACTGGTAGGATAGTCAACGATACCACCCCAGAGGCTAGTATGATTCAAAATAACACATGGACATACAGCAATAGACAAAAGATCTTTGAATGGAGTTTTATGGTGGGGTGGCGATGTGTCGACCTAAAGAGTATGTCCTAAATATACGGCTAATAATTCAAATATGTTGTATTTTGGAAAGTGTTAGAACACAAGTGACTGTTTTCGGATACAAGAAGACACAGAGATGTCCCTTGATTGTTCACAGAAAGCGTTTAAGGATCCCGTTTGACTACAATATTTGCGGATTTATGTTTCAACGAATAAATGTAAACTCGAAATTTACTATATATACAGCGCTTTCATATTCCGTTTTTCCATAGTTTGTTGGCTATGTAGTCTTTGTTTGAAAAGCGTCGTCGTTTCAAAATGGTTTCTGGGATAGTGAGTCGGGGTTAGGGATATAGTCGGCGTACTGTAGTGGTACGATGGTGGTACGGTAGGAGTACTGTATGATTACGGGTTAGTCTCAGAAAAATTGGATTTCAGCAGAAGTCGGCGGCCGCGCCAGAGGTGCAGTCCACGGCTGGTATATACATATGTATATGTATGTATATATGAATACATATATTCAACTATTTAATTTAAAAAATAAAAAAAACATTTCTCACAAATGCCGAAAACACCGAAAAATCGAACATATTTAGGCATTCGCCGATATTTTGACCAACTATTTTTTTTAGGCGAACGGCATTCGCCTTTGCCGCACAGTCCTGCATGGCACCCCGACCGGTTTCGTGACCACAATAGTTTTGATCTGAACGCAATAGGAGTCAGGAAGTTAGGGGTCATGGGTGCTGTAATCGGACCCCCAGTAAAAAGCACATATATTGACAACAAATTTTGATCGCTGTTTTTTGTCTTAATTTTTTGTCTCCCCTCGATGCGCATTACTAGTAATGATGCTTTATTTTTTTTCATGTATCTAACAAATATATCAAAAAACTGAAATTAAAGCGCTTTTGTTCAAGTTAGCAAGATAACCATTATAAAGCATTCCAAATAGATTTCAAATTAGCAAAATAAAGTGGAGAAGCTAGGATAAGATTGGGGAGTATAATTTTTCGGGCACACCTTCAGACTTTGTGGCCATAATAGCCCAAACCCACAGTTTAGTGAAAACTAGGGCTTCATTTGCTATATGGTACCCGGCACCTAACCTCTTTCAGCAATCGAATCCCAAGCAACCTTCACATCTGTAACCTTGACAAAAAACACGCAATATCAAATGGAATATAGAATTCTTTATTCAAGAATCATCATCATCATTTTTTTCAATTTTTACCGAAATGCCGAGCATATTTTTTGTCACAAGGGGAATGGCAACGGCGGGGAGCCAAGAAAATCAAAAAACAATATGGACAGAATAATGTGCCAGCGGAGCAACCATGCATAAATAATGAGGTTGGTGAGATGAAGAAAAAACAGATAAGTTACGACGCGAGGAACTACGATTTTGAAAAATAAACTGCTAAATATGTGCTTAATCCTCCCAGGTAAGCGATTATAGGACGGTTCTCGCATCTTAGCTGGCAGTTTCTCTTTCCGTATTGTTCCAGTTGACGTTGGCGAACCCGGCGTCTGAGACGATGGTGTTGAATATCAGCGTCCTCCGAACTCGGAGGCGTCTTCCTCGATCTTTCTGGCGGCCTCGAGGTTGGAAGGTATCAGTGATTGGATTTGATTTATAGTTCTTCTTGAGTTTTTTTCTTTATTTTCCTGCTTGTAATTCTAAAGCAACTAGAAAAAAAAGTTTCGGAAGGCATCTATCATGCCATGATTTGCATACCCGGTATGGGTTTGCGCGCGCGGGGGGCTTGCAACATTTTCGTAAATGACATTACGCTATGAGAGGGGGGGGGGGTGTGTAAAATAGGTATTTCTTGTCTGTCCCCGTTATCAAGTTTCTTGACGCAACGCGAGAGAAAACATACCTTCTCGTTCCTGCAACGCGGCCTCAACGATGGAGCTCTGGATGGTCGCAGTTTCCCTCGTCTCCTTCCTCATCCGTCGGCGTACTCGACAGCTTCGTTGGTCACCTGGAAATTAGAAATTAAATTTTTCTCGATTAGTTTGGCCGAATATAAAAAGTAATACTAAGAATTTCCCCATGAAAGGCTGAAAAGGGGATTGAGGTTTCCTGGGAAAAGTGAAATCCCGGTCTCAAAATTTCTTTTAATTTTTTTGAGCTCCGTTGAATACCGACAACAAAAATGGCTCTGGAATTTGAAAATTACGGGGCACCGAAACACAACTTCATCTACTGCTGCCAGTATGTCACTCCCGCATTTTTCGGAGGCTCAATCGTAGATCAAAGGTTTCCGAATAAGTTTAGATTTTTATCGAGATTGGTAACAACTAGGATTGACAAATACCAAATATCAAATATTTACCCAGATGCAAGTTTTCTGGGTGCTTTGAACTAGAATTCCTGGGAACTGATTGTAAGTGTCAAAACGCCCTCAGCCAACCGCCTAAGCCTAAGCCTAAAAAGGTGTCTCGAACTTAAATTTCGACTGGCATGGCATTCAAATGGGTATACCGATGATTTTGTTTCAGCTAAATTTTTAGGGTCGAATTTTCAAGAGCAAAATTGGGATATTTTTAAAGACTATTAATTGTCCAAAAATCCAACAATTCCAAGTTCAAATGAGCTTTAACTTGAGATCACCTTCCCAAAACCTCAACAGTATCAACTTGCGGTGGCGGTCTCGTGGCGGTTGATGGCTGCTCCTTAACAATATCCAATCAAAGGTGCCTCATTGGCGCTAGGGCAACTGGAGCCTGAGTCCTCGACAACTGGAGCTGGAGTCTCTTCAACAACTGGCGCCTCGGTTTCCTCGATCACAAATGGAACCTCAGTCTCAACGACGGCTGGGTTCGCTTCTGCAGCGGCGAGGTGCTTCAGTCTCAGCGTCGATTTCTGGAACGATTTCCTCTTGGACAGTCTCGGACTACGGTTGGCTCTGGTGCTTGCTGTCGTTCAGATGCCGTGCTTGTTCTGGTGTGCTTGCGCTGTGGCTCGACAGGCTGACGACCCGCTATGCTCGACGGGTTTTGGGACTGGCCCCTGGGTGTATGTGGTGGTCCGACTATGCTCGACAACTGAAGTGTGGGTGTGAATATGTGGGTGGGAGTGGTGCGAATCTGACTAAAAACTGTAAAAACTAACCATGAACAGCCTGGTGTGTCCTGTGGTGGAGCTTGGTAGTCGTCCTTGAGAGACTTGGGTCACCTGGATAGAGCTGACTGGTTCCGATTGGTACCCTCCTTGTTGAACTTGCTCGACTGAGAGGGTGCGGCGTTGTCTCCTCAGGTTGTGGGGCGACTGGGGTGGGAAGCTCCAGCGTATGAGGGTCCTCGAGTGGTTGGTAGCGTATGGATTCTCCGATGCCGCAGCTTGGGAAGCTCCAGCGTATGATGGTCCAGCTTGCGATCCAGCGTCGCGAAGATGCTCCTCCTCCGATTGGTCCTGAACCAGCGTAGGCAACCTCCACCGACTTGTCCTTCGAATCCTTGTCGACTGGTCCCGAGACGAGGCTCCTCAGACTGGTCCAGGTCCTCCGAAATGCATGGAGCGGCATATCCGGCTCCTCCACCGATTGGTGCCGGTGCTGGTTGTGGTGGGGGTGGAAGGCGCGGCGGGATAGCTTCCGCGTCAACGCCTCCGGTTGCGTAACAGTAAACACATGGGGTTAATAGTATGGAGGTGGCTAAAGGGAAGCAGGTTTTAGTTTTGGCGGCCAGCAGCAGGAAACAGGACAGTGATTTTGCATGAATGGTGGCAAGTAGAATGCTTTGTCCTAAGGAAGACATCAAAAGATCTTCAGAAAGAAAGAAATTATTTTTGGAATCAGGAAAAAGCATTTGAATAGCAGTAGAAAAAATATAACAATAATGTATAGTCACTAAAATACAAAAAATAATGCAAAATCATCGTTAGCTCGAGCTAGAGCATGGTGGAGCTCATCCTCCGCACGATGGCTGTGATGATGGGCAACATCCACGGGAGCTGCCGGCACCTGTCTCCGATACACGCTAACGCAGCGCGACACGGCAAATAAGACGGCTACGACATGACTCTCATCGTATTTGAGAAGGCAGAAATCGCAATGGAATGCTGAGTAACTGTCGTCGAAAGGCAACGTAGGACGTGCGTTTTCTAACAGCCACCCCAACTATTAAGTCCGCCCATGGCCGTCTGGAGGGGGCACGCGGCACGAAGCTTTCCGAAAGACGCCCGATCGCGTTTGATCGATGATGATGATGATGAAGAAGTGATGAAGCCCTCTCTCTCCGACGGAGGACACCTTATTCACCTTGGGTGCGTGTGTGTGTTGCAGTATAGGTGCAAGAAGAAGCGATCTACAAATGGGGTTCGTGGTCATTTCCGAATGATCCAATGCTGGAATATTCCTATTAATGTGACTCGTGCCACCTCATTGTTACTACTTGCGTGATTGGATATGTACCGTTGTTTCCTTTTCTAGTTAGATTCCTGAACAGTTCACCTTTACCTAATCCGGTGATCGATGTTCCAATGCTCTTCCTTTCACTTCCATTGCAGCACCTAATCAGGCGGAATATCATGCTTTCACTACTCTGCAGGTAAAGTGTGAAAATCCTAAGTTTTAGATTTCAAAGATGTCAAAAACGATCGTTGATCCTACCGCGCTTCCGCATCAACTGATATCAGGTTTTTATTAATGACAAGATTGTGGCAGAGGAATGAACTGGTTAACTTTTAGGCTGATTTAGTCTAACCCCGTGGAAAAACTTCCAGCTTTTACCTAGCGGTAACTGCAAACTACGGAGGATTAAAATACATACATTTTGTAAAAACATACATCACTTTCATAAAAATTTCGGTTTAGTTCAAAAAAGAAAAACACATTTCTGTTTTGAGATTTTTTTTTTATACACCCAAAAATGTCGATGCAATTTTGATGTTGATGCACCTAAGGGCGATTTAAAGGAAATTATGACTTTGCTGAATATTTTTGTTGTATGTCTTGATTATGGGTTTGTAGGCTTCGATGGCAGGCGCAGGGGCCGACGGGTCCTGGCGCCCGTCTGAAACTTACGCCCGCTTCACGCCGGCCTTTTGCCTCTTTTTTGCATCCCTTTTACGTGGTGCCAGGCTGTCCCATCGCAGTTTGATCCACAAAAAATACGGGAATTTTTCGCCCAAAAAAATGTGATCGTCAGCACGTCTTTAACCATACGAAATCAGTTGAGTCTCTTCGTCTCCGCATTAGTAGATCTGTGTAGATCAAGCCGTGTAGCGCGCTGACAGCACGTGTGTTTCTCATTGGAAATTGGAGGCGAAAATAAAAAGTTAGGCCATCAAAGTTTCAGCAAAAGGCGCGGATTGAGGCGAGCTCGCTTTGCTAAAGTCAGGCAGGCAGGCGGTGAACGCCTACAGGAAAAAGATTTTAGGTTATATCTGTAGGTTTCCCTTTTGTGTGTTTTTTAGACCGTCCAAAGAATCGTATCAAAATGAATAGGTATTTTCTCGTTTTAGGCAGATAGGTAAAGGTCTGTAACCTGAAAATCCAGAGCCTGATAATCCACACCTACATAATCATCAATTAAAATATTCAGATAACTGATAATTTCCTGAAAATAAGATATCTGTAAATTGAATCAACACCAATTTTAGTGGTCCATCAAATGCAACATTGTATTGATATATAAACTTTGGTAGTCAATATATGTTTTCTTATGCATTCTTCTCACTACAGTGCACCTTGATCATTGAGTACTTCATCTATTCTTGACCACTTCCTAAAAAACAAGAAATCAATCACGGCGAATATCCAAAAAGCATTAAAAAAGTACATTTAAACGAATACATTATTATTGCCCGTTCAATCCTCGTAATGTATCTTTTGCAAGTTCCTTCTTCCTCTGTCCCGTTTTGCTCCAATTCTCCGCCATACCTGATATGCTCGACTTTTTCGATCATAGACGCGAGTTGCGCAACGCGCGAAAATATCTTGCGCAATGAACAAGGAGAAGAAGAAGAAGAAGGAGTAGGAGGAGCCAAATAAAAAATAGGTGATAACCCGGGAGATGTTAAGCCAAGGAGTAAAGTGTTATAGCTTGAAGAAGGCATATTTTTGTTTCACTCCCCCCTCTGACAGCTTCTTCACTTTCACTCCAACCGTTTTTACTCTGAATGGTAATAGTTGACGGATCGCAAAGGCAAAGCCCTAATGGTCATGATTTAGAAGCAGCGGGGGTCTTGAAGGACGATCGGACAACTGAGATATGAAGCGTGAAAAACGGAACGCATGCTTATAAGAGGGGGAGATATATGGAGATTTGTTGGGAAAGAGCTATGGTACCGATTTTAATCCGGTATTGTGCTGGATTATAGTGTTTTGAAGTAGTAGCTAGGCACTGAAATTCACCCTCTAAGCCGTTAGAATTGCACATATTTTAAAACTATGCACCAGTTTTCTTAAGAACTGCTTGAAAGTTGAATTTGAACTGGTAGTTCTTGCAAAGAGGTTGAACTATCTGGTTTAGTTGCGTCCATAGTGCTTTGATAGCCCTTTTTAATTCCGCCAAGAGGAACGCCGGATTACCCATTTGCCGGGGATTTTCTTTGGCAAAGGAAATCGCCGATTTGCCGTTTGCCTAAGAAAAAATTTTTAACAGACGGAAAAACTTAACTGTGTCATTTTGAACTTATTACCGTTTTCTTGAAATATTTTCATAGAATCTAACTTTTGTAAATTGGAGATGAAGGAACATTTATATTATTTGAAATTGAAATTGTGGACCTTAAAAAAATAATTTGCAAAACCACAATTTCCCGAACTGCCGTTTTCCGCAAATTCGGCAAGTCGGCAATTCGCCGATTTGCGTAGCGAAAATTACAAGCAATTTGCATCGGAATGACAAAGCAATGTTTCCTAACATAAAATTCTAATTTTCAAGAATGATTTTTTTACTCAAAGTATTTTTATAAAAGAGCCGAATTATTTTAAATGCCCGCGCAAATAAGTGACCCCACATTTTTTACATTATTTGTATTTTCTGGCTAAATTAATTGCGGTTTTTGAATGTTTTTTATCTTTAGTATATAACTTGAGTAAAATTCACAGTAAAAATTAGTTTTGACAAGTCGATTTTTAGTTTAATTTCAGTTTCGGAGTTTCGGCAAATGTATTCTCAATTAACAAGTTTTCCAAAAAAAATCTGACAGAAAATTGACAAACCACGGTGTATCAAGCCGAGAAACCCTGACACCACTTGTGATTCCCCTTGGAGGCCCGCCTAGATCAAAAGTTGGGCCACCATCATTTTTGTTCGAACTCAATTGGTAAACTTTGCAGACTAGGCTGACACGTGGTATTTAAATACAATTTTCCACATTTATTTTCCACAAACCGAATAAAATCCTTATCTGAACAGTGTTATATAATTTTTTTCTTCAGATCACTCGACAATTTAAAATATATTACAGCATTCTTCTTTAGATGTTGAACGTTGATGCTTAGGATAAACATGAAAACCAGATCAGCTTTTCCGTGACCTCAAATACTCATTTTCTCAAATTCTCAAAAATGTTCTGCCTTCTCCAACGGTCTCTAAAAAAGCTTGGAAAACCCACAAAAGGTGTCTTGGGAGGGACACTCTCTTTTATCGATGACCGGAACGCCGGTATAAATGGGTTTTGCGGACTGACACCAGCAGGTGGAAATGGGCGACACTAGTAAAATAAAGAAAAATAATAATACTGAAAAAACAACACGGTATGCGAACAGAGAGTAGTGGCAAGATCGGAAGAATGGTCGGGGGGGGAGGGGGGGGGGATTACATAAAGATGTCGGCATAAAGTGCGTTTCATTAGGGTTGGGATTTTTATAGGGGGAAACTTTGATTTTTTTGAAAAATAAATTAAATAAGAAAGAAGCGACAACAACCAACAACAAGGTCATTTTTAAAAGGAAAATTTGGCTTGAAACTTAAACATTTTGGGATGAATTATGAGGATATACTCATAGATTAACCTAATTTAACAAAAAACACGTCGTCGAAATTTTTAAAAATGAAGCTACTGCAATTTTGAAATTTGGTGGTCCTAAGAAATCTATGGTTTTGTGGTATTTTGACGATAAACTGATTTTTTGTGTTTTTTTTCTGGTATTTTGAAGCCGCTGTACTTCAAACCCTTTTCATATTCTCAAAAATATCTTTGCAAAATTCGGTTTTCTCTAAAGAAAATTTCAAACTAAACCACTATTTTCAATTTTTAAAAATCTGCAGATAAGATATCGGAAAATTCCGGCAATTTGCCGATTTGCCATAAAAGTTCCGGCAACTTGCAGATTTTCCTATTTGCCGTAAATTTCAAATTCCGGCAAATTGGCGAATTCACGCCGGTCCTACCAGTGATGAATAAATCTTGTTTTTTTCTGGTATTTTGAGACCGCCGTACTTCAAACAATTTTCATAGTTTTACATATCTTTCAGCGAGCGGTTTTTTTTGAATATCAAAATAAACCAAAAGTCTACTTTTTGTGGTTTGTTTTTGTAATTTTTTTTTTAGAAATTTCAATTTTAAGATATCGGCAAATTGGCAATTTGCCGGTTTGCCGGAAAATTTTAATGTAGATCTGGCGATTTGCTGCTTTGCCGATTTGCAGGAAATACTCTATCCCTGATGTAAATTACCAGAATTAGAAATGTGGTATAGCACGATTGGCACACAATTTTTTAGTACTAAGGATAACACGCTGAAAATTAAATTTTTGAAAAAAAAAATTCTTGAAATTGTTTTAGTAATTTCGTAATCAATTTATATCATTTTTAGCCTTTTGCTCCAAACTAGGTTTTCTCCCACGTGGCATCTCTCATTACACATAAAAATCCCTGCTAACTCAAAACATTAAGTTGTCAGAGATTCATATCCATGTCCGCTTCACTTTCCAACTTTTTCCCTCTTAGCTTATCTAGATATACGTATATCTATCTACAAGTGCAACAACGTTCTCTTTTCAAACATCCAGTTTATCTTCTGACCTTTGCAACATTTTTCCTTCCAAACTTCCAGATTGCATATTATTCTTACATTCAAAGAGTGTCTCAAGTTTTGCTTAGAAGAAACATAAGGTAAAATGTCAGAATATCTGTTTACAGCATTGTAATGGCAATTTATTGTAAATATTCGCAATTTTGAATCTCCCTTAAAATGGTTAATTTTGTAGTTAGAGGACTAAATTAATGCCCAAGAAAAAGTTGTCATTTTTCATTTATCAATGATTGTACATAATTTCATGCCAAAGAAAAAATTTTGCCAAAAAAAGGACAGTCATTAGAAAAAAAAACGGAAAAATGATCTGGATCAGTGATTCTTTTTTATTATCTAAAAATAATCAGCATAGTCAAATGTACCAGAAAAAAGCAAATAAAATGTACTAGATTGACCGGAAGATTATTTGAAAAATTGCAGAAAATGCACCAAAAGCTGCTTTTTTCAAAAATTCACAAGTAGGATACAATTACGGAGCTATTCTTTTTATTTCGTAAAACTCTTCGCATAGTCAATAATACCATAATATGTCGATGAAAGTATAATATCTTGTAGTAAGTATCTTTTTAAAAATTGATAAAAATATATAAAAGCTGTTTTTTTCAGGGAAACTGAAAATCCAAATGGAGGGAAAAACATAAGGCATTCTTTTTTATTGCAGCTCATAAAACTCTTCAGCATAGTCAAAAATACCAAAATATGTCAATTAAAGTATAATAGCTTGTACGGAAGTATTTTTTTAAAAATTGATAAAAATATATAAAAGCTGTTTTTTTCACTTGCAAAACAAAAGTATGGGAAAATCATATGGAGTCATTCTTTTGTATTTCATAAAACTCTTCAGCATAGTCTCCCAAAAATACCAGATTATATCAATCAAAGTATAATAGCTTGTACGGACGTATTTTTTTAAAAATTGATAAAAATATATAAAAGCTGATTTTGTCAAAGACCAAAGTCAAAAGTACGGGAAAATCATAAGGAGTCATTCTTTTTTATTCATACTCTTCCCAGAGGTCCATAGCCAAAAATACCAGAATATGCCAATCAAAGTATTGTAGCTTGTACGGAAGAATTTTTTTAAAAATTGATAAAAACAAATAAAAGCTGCAATTTTTTGAAAAATTCAAAAATTCAAAAGTATAGGAAAATCATATGGAGTCATTCTTTTTTTATAAAATTCTTTACGGAAGCATAGTCACAAATACGAGAATATTCAAAAGATAATAGTACGGAATTTTTTTTTTTTGATAAAATATATAAAACTGAATTTTTCAAAAACCCTTCAAAAGTAGGGAAAACTATATGGAGCGCTTCTTTTTTCTGTAAACTGTTCATCATTACGGGTAATACCTGAAACTACCAAAAAAAGTAAGCTAGCATGTACGGAAGATTATTTGAAAAATTGCAGAAAATGCACCAAAAGCTACTTTTTTCAAAAATTCAAAAGTATGGAAAAATCATATGGAGCGATTCTTTTTTCTTTTATAAAACTGTCAGCATAGTAAAATGTACCAGAGAATACCAAAAAAAAGTTGGTATGCTAGATGTTCGAAAAATTGTTTTTATGGCGTAATTTCTGAAGAGGAGTTTCGAAAATGTGAATATTTCCCAAAAATGGACATTCTTGCCACTTTTTACTAATTTTTGATGGGCTAAACCTAGATTTTTAACGCTAAATTTTACATTTATGAGTTACCCGTTTTATCGACAAATTCAGGCAGATTTTTATTTTTTCCTATTTTTTTAAGCCATTTAATCAGCCATAATAGTGAATGTCTTTTTGGGCAAAAAAAAATTTTTTAAGGCTGACCAATTTTAAGCTCTCCAGCTATAAAATGAACCATTTTAGAGGAGTTTCAAAATTGTGAATTTTTACAAATATTGCCCCAATTTTCCACTTTGTAATGGTTTTTGGTGGGTTAAACCAAGATTGTATTCTGCATACATGAATTACGCGTTTTCAACAAATCTTAACAAATTTGTTTCTATTTTTTCCAAAATTTTTTTCCCTCAGCCATCTATTCCTTTTTTTTGTCTGTTTTTTTAGGGCAAAAAAACCTTTCCCACGTACCACCTTTAATAACACGGTAAACTGGTCTAAAAATCGGCAAGCGGAATGAAACTTCAAGTAATATAATGCGATGAATTGAGTTTTTTTTTCTATTTTCTTTGTTGAAAATATCAATATGAAAAAAAATGAGTAAAATTATATTGACATAGTTAATCGGATATAAATAATAAAACATCACAAGCACATTTAATTTTTCAAACCCACTCAGGAGTCATGAAGAAATCCTTCTCTGCACATCTAGCTTTCTCCACATCCAACTACTTTTATTATCTCCAGCAAACTCCGTGTAACTTTTATTGCATACACATTCAAAAGTTTTGTATGATGCTTCAAGTCCCAAGTCGATTACACAATCCCCGAAAAGAGCATCGCTGCGAATTATGTCAATTCCCTCTTCTAAATGCACTTGTTCTACAAACTTCACTGATTTCCTTAGGATGCCACAGTCCCCAGGCAACAGTTTGTGCAAATTCTCAAGGTTTGATTTCAGTGGGCAAGCGGCAGGTAGCGCTCATTTTAAATTATTGATTTTTTTAAAACATTATTAACTCACTTCGTCGCTTTCATGTGCTCTTCTTGGATTATGGTCATATGGTAACTAAGAATCTCGAAAGTTGTTTAAATCCCAAAAAGATCACATTTTTCCTTTCAAACGCATTTTCTCGTTTACAATGTGACATCTCTTGTTCAGTAGTTGGAGTCGGCCTCTGTCGCAGATAGTGTGACCAGAGCAAGTGCCTATTCAAGGGATTTGGGTATATCATGATCTGGAAAATTTGGTATGTAGGGCTTCCATGGTAGGCAGGCGCGGGGCCTGGATGACCCGCTCCCACCGGTGAATTTACAATGATTTTCTCGTATAAATTTTGTCATTTTGATGAAACAAAATTGAGGGTACAGGCAGGCGGAGGTCGCCTCAACTCGGCGTTTGCCGCCACCAAGATTCAATCTACCTGTCCAAAGCATAGCAACTTCTAACCCAACCGCCTTGCCTCAAAAAAAATAAAAAGCTTAAATATCAAAATTACTCAATTTTGTGTCAACCTATTCTACTTTTCTGAGACAATTTGAATTCCCTCCAAAAATTTTATTGGAAAACAAGTTTGAACTTTCACTGGCCAAAATTTTTTTTGGCTGCGCCAAAGATGATCAAATATTCTCGGCAAGATTTTTCCCAGACCCCAATTGAACTTCTTGCCAAAAATTTTGATAATTTGAATGGCAAAAATTATCTTGCCTTATGGTGAGGACACAATCAATAGTTGTCAAAATTGTATATGTCTGTCAAATTTTTGATGTGTGTTGGCAATTTTGGCAAAGCATTTGCCGAGCTGTCTCGGCAAATTCGGCAAATTTGCCGAGCTCGGCAAATTCGGCAAATCTACTTTTCGAAATTCGCCAAATTTGGCAAACGGCAGAAAAAAGTACAGAGATTTGAGGTACACAAGGCTTACATCGAAATTAATCTAATTAAAAGAATGATCACTTACCATATATAGCATATACTGCATATTTCAGTGACCTTCTTCGCAACAATAGTCTAGACACTGCCCAAACACTACACACTTGATGCTATTTATGTACTTTCTATGCTGAGCAAACAGAACATGCGATTTGAGGAATCTTAGGTAGCAGCAAAAAGATTGACATATGATTAAATTCCTAATTTGTTCCTTAGCTTCCCGTATGTCAATTAATTCGTAGATAGTTGCTATTGAGAAAAGTTTTTCGAAAATTTGTAAGATATCAAAATAATAGTCCTCATTTTTAATTTAATGATAGAGTACTTTGAAAATTTCAACAATTTCAACACTTTTGTAACACCTATGTTATCAATCAAATACAACAGTTTAGTACAGTAATCCTACATTTCCAGCCCACGTGGTATTAAGACAGTGTTAACCTTGTTATTTTTTAAGGACTAAAAAAATTTAGAAAATTTTTCTTCCCATTTTGCTTACTTATCAAAAAAGCATCGTGCCCTCATTTAAAAAAGAAGGGTCGTCGCTGGAAAATGTTAAAAATTTCTCTCATGATGCGCTAAAATTACTTAACTGTTTAAAAACATTATAAGTATCGTAGCGAATTTCAAAAATCTTCAAAATTTAGATTTATTTATAGTCAACAGTTTTGGAAGTCAATTAAAAACATTTTTTACTATTTTTAATATTTACAAACGTTATAGTCAGTTGCTTGTAACTTTATAACTCCGTTGCCTACCGTACATTTAAAACAACCGTAAAAATCTAAGCTTTTCTCCCGATAAAAATCTTTACTCAGGCGCGCGACTCTTTTCTTACATATCTTTCTGAATCTAATCAATATTGAGCTCATACTAGCTGTAAAATTGAACATACATATAACTTTGAGTGCAATTTCGACCCATAATTTCAGAAAATTTTCACACACAGAAATCTTTATTGAGAATGATCAGGACAGTTTGACCTTTCATGAGAATTGCTTGGAGAAAATTCCAATCGCACAAAATTCCTCATTGCCAAGTATTTCCTTTAGTTTGTGGCCAACGCCTTAAAAAATAGAAGACATATTAAAAAAAAAACTCTGACACCACGTGATTATGCAATCCGACTCATCGTCAACACACGGGGTTCTGCCCTTCCTTATTGAATTTTTCGCGCTCCATTGACAATCACCCCACGCCGTCCGACACGTGTGAAAGTCGTCACTCCACAAGGAAAAATACATTTAGTTTTACGTTCGAACTAAAATCGAGCCGCGACGCAACACGCGACGCGCCGTAAATCTACACCAGCTACTCTATGGCCAACCGAAATGGCCTAGCTCACAAACTCTTCCATTTCAATTTATAAGCCAGAAACCCGTGCGAACTGCGAGCCTAACGCTCTTTTTCAAAATATCGTATAACTCGGATAACAAGCCATATTACCAATTCCTGTTTTATTTCGAAAAACAGATAATACAAAAGAAACATATCTGAAAATTAAGAATAGATTACATGTTTTTATCAAATACTTCTTTGTCTATATTCCATAAATGACCCCCATGCGAATGAAACACTCACTATACATTCAAAATGAATTTCGCACTTGTCGCTTTCCTCGCTCTCGCTAACATTTGAGGACTTGCACAGGGTGATCCAGGACTCTCATTTGAGAGAAGATTCAGTAAATATTGTAAGCTTTCGGATTAATGGTTACAACATCTATTAGATTGAATGGCAAAGTGCCAGTGGGAGCAGTGAAGACGTTGGTTAATGATCTTGTGAGCCCTACTACTATTTAGGGGGTGGAGAAAAACAACATTATCCTCATTGTCAGTTTAAGGAGCTACGGGAGGGCTCCATCTCAAATGTTTCAAATAACTCATATTGTACCTTTCTCTGGTGAGTAAAATAAATTACATATTCGGAATCCTTTTCTTTTTGATGTTAACCAAGTTGCCGGTTGCCAAATTTTGTTGGGTTCGGCAACTTGGGCAACTGGGTATCAATGTCAAACATTTTGAAGCTTAGAAAAAAGCATTCAGAGAGCCTGAAAAATTCTATAATTTCATTCTAAACGAAAACTACTTTTTTACCAAAACGCTGAAAAATATAATTTCAACAAAACATTGAAACGTGGTTGCCCGACTGAATATTTTGGGGTTCGGCAATTGCCGGTTGCCCGTTAACCTCGGTTGCCGCACGGCCCTGATGTGGAACTCGCCTAGTGTGTCGCATACTTCAATGTGAAGGCGTATTGTATTTTTTTAAACATAAATTAAAAATTCGCTAAAACCGTCATAGCATATATAAATTGTTTAGACCGGTGAATAAAAGGATAGGATGCCACGCGAGTGCGAACGCTTTTCTCCGAAGATCCAAGTCAGGACGTCGATGGGCGGGACCCGGTGGGCGGAGGTTAGTCGGATAGAGCAGCAGACAAAACATCCGGGCGGCGAGATCAAGTGCGTACTCCTCGACGGAAAGGGAACTTGAGGCGCGTGGATTGGTTCTCGTCAGATGAGGAAAGATTCTAAAGGGAGGCGACCGGAGCCAGTTGTGGGAGCTCCTGTCAAAGTCGTTCTCTTAAGGGAAACAAATAGTGGTGTTAAGGGGAAATGCGATGGGAAATCCGAGTAGTTGATGGCGGAATTTTCTCGCGGGTTTCATCCTGGAAATTTAATTAGGGCCGCGGATTTCAACTTGCCGAGTTTTTATTCGCTTTTATGAAAAAAATTACTCGACAAATGGTTTTTTTTAATTAAAGTATCCGAAATCCCCGAAAACAGGCCATTTTAGAGAGAGGTCACTAGAGGTTTCGCGACATGGAAATATGTATTCAAGGATTCTTAGGTAACTACCCAATTTTTTTACCTCGAGTTTAATAAATTTCAGGTAAATCCTCTTGAATAATTCTAGTTTTGTTGTTTTACACAAAAATTCGGTTCCTCTTTATTCCGCGGAGTAGCTTTCCAGAGGTTGAAATATTTTTCCGGAGTCAACTCCTACCCGAGTTTTTTATCTCGATTTGAAACATAATCGGCATAAGAAACTACAATTATTTGTTTTCGGGGTTAGAAACTTTAAAAAATGGCCCCAGAAAGTTGCTGGAAATTAGCTTTCCCGAGGTTTCATGGAAATTTGTTTTTGCGGATTTCGACTACCCGAGTGTTTTACATCAATTCATTTCTAATCGACATAAGAGACTACACTTATTTGTTTGGGGCGAAAGCTAAAAAATCCCCGGAAATCTGGATTTCTAGAAACTAGATTTCCCAGTTTGGTTCATGGAAATTTGATTCCGCGTATTTCAACTACCCGAAATTTCAATCTTTAAAAAACATCCAGTTTTTGTGAGATGTTCTTAAAAATAGCTATCAGACGTGATGGAATCCTAAATTTCTAACTATAGTTTCCGCGGGTCGAATTTCTAGAAATGACCTTTCCAGGTTTCATGGAAATTAGTTTCCGCGGATTTCAACTTCCTCGAAGCATTGGATTGCAATATAATTCGCACAATAAAAAAAGCCAAAAGGCGAGGATCCCTGGTAGTTTAAATCCGCAAGAATAGTTTTCTCTAGTTTGAAAAGTTAATACTGAAACCCTTACTTATGCTTTCATTAACCAAGAATTCGATCCGTCGAACAATTGCTTTGCAGTCCCAATATTCGGCGAAAATTTCGATGGTTATTCCGACGGTGCTCTTCGATTTTTCGCAGGGTTTGCTGATACCTGAAAAATCGATATTTCAGACTATCTATGCCAAAAACTAATTAATTAGTTTACCTTCTGACTAGCATCCTCCAGCTCTACAATGTAATGAATGGCGGCTTTATACTGTTTCAGCTTCTTCTCAAGTAAAATCTGAACACAACCCGTTTGCCGTGCCATTACTCAACCTGAGCATGAGCACTATCTTGTCGGCGCACACATGGCCCGAAGTTGAGAGCCAAGTTGAGCCCATTTTATGTTGACGGCGTCCTGTCGGCGCCACGTGCCAAATGATACATTAGGTGATCAGAGCACGGCGCGGTTCGGTTGTGGGAGAAGCTCGTTCATTACGGAAAGACAACCGGACACGTTCACCCATATCCCACTTCTGTAATTTTGTTTTTTTGGACGAAAAAAAACAACAAAAAATATCATTTTGACAAAATGTTAACTGTCAGAAAATTTGAAAATTGATTTATTATTTTTGTTTCAATTTTTAGTTTTAAATGAATGAATGGATTCCGATTTTTGTAGGAATTGTCGAAATTTTTAATAAGAGCCCTAGTAGGCATGTGTGTGTGTCTCATCGGCTTGACCTACGTAGATCTACAAAAAAATGCGGGAGAATCAGAGGTCTTAATGGATTTCTCATGGTTAACAATATGCTGACGTAACTTCTGGGTAAACACATATTTCCGCAATTTATTGTAGATCAAACCGTATTGAGACAGCATCTCTGCCTGGCTGGGGACGCCTCTTTTTTCCCTTGGAATTTTTTTGGCGCGAAATTCAACTTTTTGCAAGTAAGTGCGAATATTTTCAAGCAAAGTGAGACTACGTACAAAATTATTTTGCTGCCAAAGTTTTTGAGTTTGCAAATAAATTATTGAGCAAAATTCAAATGATATTTTTCTTTCGAAACGTAATGAAAAAACTCAAAGTTACAAATAATTTGGCGCGAAATTTGATTTTTCAAAGATTTCTAGCGTGGCAAAATTTGAATTGGAATAATTCTGGTCCAGAATTCAAAAATTAAAAAGAAATTAGTTTGAACGATGCGATGCCCTGGTTTTCATAGAGCTTCCATGTAGGCGTTAGAAAACGCCTGCCTGCCTTATGCCGCGCCTATGCTTGCATATACGTAAACTTTTTTTCATTTCGTATCCTAATTTGATTCAGTTGACAAGTTGATAGAATTGAGAAAATTATAATTTAACGCATTTATCCTCTTAAAAATGCAACAAAAAGGGTTCAGGGCAGGTGCCAGGCCCTGAAGCGCCTGCCTACCATGAAAGCCTATCGTAAATAATCCAAATTTAATTTTTAATTTTACTAAAATTTCGATGGCTCGTTTTTTTTCAAACATCACAAACCTGAACAGTCAAAAAATTTTCGAGACTCAAAAATGATAATTGGTTCGGCGAGTTCTCGGAAGTCTAACGCCCATTATTGACAAGTGTAGCACATGAACTCCAATATCCTCAAGATTCATCATATCCGCCTGAATCTCCGAATCACGCTTGATTTTTTTTTGTTCAATTTTTCTGCAGTTCAACTCCAATTACCTGCAGTCGATTCAATCACTTGTCTGATACTGCGGATGAACTTGGGGTAGAGATCAACTGTTTCTGAAATTACTGGCGCAAAAAATTCATTAGATTTCAAAGACCAAGTATTTCGGTACCTATAAACTCCTTCCATTCTCAGAACCCCCAGGGACGCCACGTGTCTCAATTGCAAAAAAGAGTCGGTCCCAGAAGTGTTGGCACAGTATGCTCATCATCGACGATTGATACTAAATAGGCACCAAAGCTTCCACCAAGTTTGTCTGAAATTCAATCTTTATAATAGCATTATAAAAGCATATTTGTTGCAGTAGTTTGTAACAGGGGTCAGACAAATTGCCAAGCAAATTTCCGCTGGCAAATCGGTAAACCGGCCTCCCGGTCTGGATTTGCTAAAAATTTTTGGCAACCTTCTTTTGGAATTTTCAGAAAATTTACATTTTTATCGGCAACCCAATTTTACGCATCGTATGAATTTTCTTACATTTATTTTGAGAAGTAAGCAAATTCTATGAAAACATCTGAAGTAAACGAGAAAAAAAAATTAAAGGCACAGTTTTAAGTGTTTCCGTCTTATAAAAAATCCCTCTAAACATTTCCGGGAAAACTGATATCCGACAATTGCCGGAATTGAAAAATTCCGGCAAATTTTGATTCTGAAGCGTCTTTATCAAAAAAACTGTTGGTAAAATACAAATTTTATTTGATTTTCAAATATGTTTTTTTTTTCAGAAAAGTGAATTTTTTGCCGGGAATTAGGCAAATAATTCTGCTCATGAAAATGTTTCAAGATTTTTTTGCCACGAAATCAGACGGTTTGAGAACAGTTTTAGCGGAAAGTTAAAAAAAAATTTCAAAATTTTTGGCAATGGAAGTAAATATTTTTCAGAACATGTATCCGAACAGTTTTGGCTGTAAATTAATCAAATGTTTAGTTTTCAACAACTCTTCGCGGAGGATCCAATATTTTTCAGAATTTTGGAAATTAAAAATTTATCGAAAATAAATTGCAATTTATAAGAAAGCAGTTGTAATTTTTTTTCAAAAAGGTACCGAAAAAATCTGGCGAATTTGGCAAATCCTTGAGCTGAACAAACCCGGAAAAACGCAATCATTTTATCCTTTGACTTTTTGGATCAGGTTCAAAATTACTGAATTCCTACAATGAGTCCACGTCAGATTTTTCTATAAGCTCCGTTTGGTCTACTTGTATAAAGCTCGAAATATCTCAATGTTATGTTATTTTACTAGATTTTTTCAAAATCAATAAGTTTTTTTCGGGTAAATTATATTGTTCATTTTGTGGTGTGTGCGTGCTCTGAAATTTCACACTTTGCCGAGCTCGGCAAATGCAAATTCCCGCACACCCCTGTATTACTCACCTTCGGAAATCGCCTTACCATCTGACAGGGATGTGTGACCTTCGGCTGATACTTATGACACGATATCCGGACCACGCAACACAAGTTTACAGCTTCTCATGGAGCCATATTAACTGAATACACACTTCAACAATAAGTCCAACGGCACATGGACTGCTTCGGCACGAAATCGGTGACCAGCATGTACCTGGAATATTGGAATTGCGTGGGCAGGGTTCCTGACACTAGTTTCATTTGTCTAAAAAATTTTTTTTTAACTGCCTGAAATTAGTCCAAAATTACATGTTATCTTTTCTCAAAATGTGTGAAAATTGCACACTGAATTAATAAATAATATTACTTTTGTAAGAACATAAAAAGGGGAAAAGTCAGCGGTAAAAAAGTAAAAACACTCAGAGTTAGATCTGTTGACCTCAAAAAGTTCCATGAAAATTTCCTTCTTTTTTTTCAGAGATGTGACGTCGTAGCGGCAATTTCCGTTCGGTAAACATTTATTTTCGGCAAATACGGCAAATAGCTTCCCCGATTCGCAGTTTGCCAGTAGGATACCAATTTGCCGGAAGTTAAAGTTTTAAAAATTCCAGCAACTTAAAACTATTCTAACATTTTTGAAATGTTTTTTTACTATTTTCTCTAGATATTTTTAGAATTTACTTACTGTTCAAGCCCACAGCTTGCCGAAAATTTCCGGCAAACTGTCGGTTTGCCAAAATGGCCGGAAATTTGAGAAACGGCAATTTGTCCGTTTTGCCGTTTTCTAAAAAAATTTTCGCAATTACTGTATTAGCCGTTTGCCGAAAAACTAAATATGCCTCCCATCGTCACACAATACAAAAAAATTGCGCGGCTTCTGGAGATCAAATCTGACAGCTTACTGTACTTATAACTACAAATTCACGCTGTGTTTTTATCTAATTCACGTGGTGTCAGGGTGTCTCAGGCTTGTTCTACGTATATCTACAAAAACGGGGGCAGAGACGGAGGAATGTGCTAACGTCACTTTTTTTTTGAAAAAAAAAAAATTCCCGCATTTTTTGTAGATCAAACCGAACCGTAATGGGACATGTTAACCTGGCGCCACGTGCTAATAGTAGTCACTACATTCTTACCGCCGCTCTGATATTACACGCCGATTCTTTCCAACTTTCTGAATACCAATTACACCATTTTCTCGGATTTTGATATATAATACCGCGGGCTTCAGACTTCCGTCTCATATTTTCAGAATGTAAGAGTTTAGCGAAAGGTCATTTGGGCTAGGCTACGGCGCGTTGCAGCTCGCTTTTCTTTGCAAAACTAAATCGGCGTATCTGTCCGATTTTCATTGGAGCGCGAAAGGAAAACTAGAAGCCCATGTATTAAAAAATGCCGACTTACCTTTCGTTGATGAACTCATTTCTCCTTCCCGCTTCTTTTCCGATTGCACATGAACCTTCGTTCAGGAAACTTCTGGAATTGCTGAGAGTAAAAAATTGTTTTGTTACGAACGCGCCCAGCCCTAATAAAAATTGATGGTGTATACCACGTTGGAAATTATACAACAATACGGAGCACTTTGCTCGAAGCCTAACATTTTCTAAATGTTTTCTCACCTAAGACAAAAACTCCAAGTATTGTCGGAAAGGATACACTGTCCTCGAGACAGACTTTCGTTGAAAGTACCTCGAACATTGTGATGAGGGTATTTTAGCACGGATTGCTCGAGCTGAAAGCTGATATGTTGCTTATTACACTTGCGTGGCCGTGAACCCCAAAAACTAGGCCACCTTTTGCGCCCAATTACCGATAAAACCCCAAAGCCTCATATCGCAACAGCTCCATCATGGACAGCTCTTAGCGACTTTTTTAAGACCGCATCCACTACAGTATCGCTTTTGGCATTACTCTCGTTTAGATGACGTGTCTCGTTGAAAATAAAAAACTGAATTGTCGGAGATAGGGACGTCGGTGGATTCTACTAGCATGTTTCCAGGATCGATCTGTAAGTATTGTGCTTTAAGTACAACTACTGCTTCAGTTTGATACGCATTGTAGTTTATAGATTGTGGTTTGTGTTTTGTAGTTTGTGGAGTTTTTAGCACTATGTGTGAAGCTTGATATTCATTTTGCAGCACATTGACTTGGATTGGGGTGTGCTAAGATATAATATCAAAGTCCAGAACGTCACGAATAAAACATCTCAATCCGGAAACTACAAACTAAACCCTACAGACACTTACAAACTACAGACTATATCCTACAGACTACAAACTACAAACTAGAAATCACAAACTACATCTACGCAAAAGAACGTTACCTACCTGTTGCTTGACTGGTTTGTGTTAAACTGAACGTGCCGGTCGATGGAATTGGTGAGGAGGATTGACGCTGCTTGTGGGGCCTGGAGTTTTCAATATTTTTTTGTTTCAATTAAGAATTTCCTTAAATATACCTTACATCAAATCCCATGGCCGTTTCGGTGAATGCAGCCGAGTTGGTTATCGAACTGGTGACGTGGGATTGCACGGAATGGAGGACTGGCGGCGAAGACGAAGCATTCCTTGTGCAGGCACATTTTGCATCCTGGTAGAGGTCGTCAAATTACGGCTTCTAGGTCATTGTGGCCGTGGCCGATGCTTTAAGGGATGCTAGGTCATCTGACGTCACATTTTTTGTGGTTTTTCTAGGACACGTTACAAAGAGTTCGAAGCGCCCAATTTTCGGAGAGGTTACTAGGCCATGCAAATGTTTTTGAGGTTTCTAGGCCAGTAGAATATTGTTTCTAGGCCGCAGTAGAGAATTTTAGGCCATATCTGACGTCACAGTTTTTGGGACGCGGCCTAATAACGATGGTGGACCTCTCTTCTGGGAGGAGCAACAATACATTTTTTACGAATTTCAACAATAGAAGATGCAACTTCACTATGACCACTCATGTGGTGCGAGGTCTGCTCATTACGGTTTTATCTACAAAAATGCGGGAACTTTTTTCCCAAAAAAATGTGGCGCCGCCACGTTCTTAAACTTGCAAAATCAGTTGAAACCTCTGTGTCTCTTCTCCCGTGGCATTTTTTTTAGATACGTAGATCAAACCAAAATGAGACCACACACACACACAAAAACCACTCTGACACTTGTGCGCCTGGATGAAGTTCGTCAGGTGCCGGCAATTGCAAAGAGCACATATCTCCTGCCCATGGGAAGTCGTGACATCATGTTTGAATTGATGGTTTTTTGGGACGACACGTCCGGCGACAGTTCGGCAAAACTTGTGTCCCGGAGACGGTTCATCCTCGTCCTCGTTCCTGCCCAAAAGTGCCTTCAAATTCTTTTTTGCCTTCAGGAATCCCAACTTTCAAGCGCTTCCTTTTTGGAATGTGTTGGGCTTGCTGAAAATATTCAAAAGTTTTATTATAAGCCATAGAACCCTTACCGTGATCTTCACATCTTGACATTGAGAAATTGTTGGATGCGGTACTATTAGCTGACCTTCCGTAACATTTTTAACTTAGTGGTTGAAGCCGTAGGGGCCAGAGATTGCCGTCTATGATGGGACCTAGATCAGCTCCTTCAATGAGCTTCAACTTTGTGTCTTCCGGGATAACTGGTCCACGTCGACGGCGTCATCGCTAAAAAGGTTTGCTGTGTTACGGTAAGCGAGAATTATGGCAGAGGTGGGCATTGCCGTTCGGGAAATTTTTTGTCGAAAAATTGCCGGTTTGCCGAAAATTTGAATTCCGACATTTTGTCGGCGTAGTTTCCCAGAAATTTTCAATTCCGGCAATCTGCCGATTTGCCGGAAAATTTCAATTTCAGCACGTTGTCGATTTACCGGAAATTTAAATTGCGACAATTTGCCAATTTACCGGAAATTTCAATTCAGGCCATGCTGTCGGAAATTTCAATTCCGGCAAGACAATTTGCCGATCTGGTTTCCGGAAATTTCATATCCGGCAATTTACCGATTTGCTTGTGGAGAATATCAATTCCGACAGTTTGCGAATTTTCCAGAAAAATTTCAATTGCGGCGATTTGTAGATTTGCCTGTAAATTTTCAATTCCGGTAATTTTCGCCGATTTACCGATAAAATTTCAATTCGGCAATTTGTGAATTTTCCAGAAAATTTCAGTTCCGGCAATTTGCCGATTTGCCTGGACAATTCCAATTCCGGCAACTTACTTTACCGAATATATCAATTCGGCAATTTGCGAATTTTCCAGAAAATTTCAATTCCGGCAAGTTGAAGATTTGCCTGGAAATTTTCAATTCCGGCAATTTCGTGCCGATTTACCGAAAAGGCTCTGCAAGTCCTTCGGTAATTTGTGAATTTTCTCCAGAAAATTTAAATTCCGGCAATTTGCCGATTTACCACTGGAAAATTTCAGTTACGTATGCCGATTTACCGGCAATCTCAATCCGGCAATTTGCGAACTTTCCAGAAAATATTCCGGCAATTTTGCCGATTTAAAGGAAATTTCAGCATAATTAAGGCTACGTTCGCCGCTTTACCGGAAATTTCAATCCGGCAAGACATTTTGTTTTTCCAGAAAATTTCAATTCCGGCAATTTAACGGCCGAGTTTCCTGTTTCAATTCCGTTTGCCTGCCTGGGAAATTTAAATTCCGGCAATTTGCCGATTTGCCGAAAAAATTCTGGTACATTATTTCCTAGAAAATTTTCAATTCCGGCAATTTTCCGCTTCACCGGCGAATTTTAAAATCCAACAATTCTGGCACATTGCAGATTTGCCAGAAAATTTCAATTCTGGGAGTTTGCCGTTTTACTGGAGATTTAAATTCCGGCAGTTGCCGATTTGCCAGAAAATGATTCAATTCTGGCAATTTGCCGCTTTACCAGAAATTTAAATTTCGGCAATTTGCCGAGAGTTTTGCTGAAAATTTAAATTCCTAAGAAACTGTGACCGAGATCAGTTTTGACGTCTCTTCCAGAAAATGCACTAAGGTGATGTGACGTCATGACTGAGTTTCGAGGCACGTTTCGTTAACTTGGCGGAGGACCTAATATCCAAGGGAAATAAATTCTTTTTAAATTTCATAATTTTCTGAAAAAAAACTCACTCCTGAGAAAGTCAAGTCTCTCTTCCGGAATCATCATAAACCAAGCCCATCCTGTGTAGACTTATCACTATCTGTATCATCACCCGAAAGAGCAAAAGCCGCCAGAGAGCTCGGAGCACTCAAGTCGAACTTTGTTAGCATTGCTCGAACCTTCGTCTACGATCTATACGATAACTTCTTAACGCTCAAGGCTCCATTGCCCTTGGGAATCTCGCCGACTCGCTTGCGAACCGATGCTCCGAGATACGCAGACTGCAGAGCTATCACCGATTCTCTTATCATAAATATTTCTGTCGTTGCTTGTACTTCTTCCAATTACACTGTATCGTTTGAGCTGCTAACGCTTTTTTCCAAACTTCCGCACCTCTCAAATGATCGAAACAATCGCTTGATCTTGATAAGTAATCTTCATTCTCAAATATCGCTTTCTAGCCAATATTGTCCTGAACCATCGTTGAAGAGTATCGATTGATTACATAATGGTCCGATGCAAATGATCATCGAGAACTTTTCAGCGTCTCTCTAATAAAAATCTTGGCAATTGGTTCCATATTGAGTATTATCATTACAATTGTGCAATCGTTGCATGGGAATGTATGTACTCTTTCACATCGTCCACAGTACTATCCCTTCCGTTTCGCAAAAGAATTCGGTATTGTTGGACAAAGCTTGGATACGAATTCAATTCTCATCTCAGTACCCGGCTGTCCGAATTCGAACGGTCTCGATAGCATTCCGGTGTAGGAGCTGGCGGAGGGTTATGTTGTAGTCGTCGCAAGTGGTTAGCGATCTATAAAATTTTAGGTGGTTTTTGATAATTTCTACTTATATTCAGTCATATAAATAAACACATATAAGTACCAAAAATTTCGATCACCTAATTTTTCTTAATTTTTTCTATACTCTTACTAGTATGAAAGAGCAGGATACAAAAATAACTCCACAAGTGATAAACCAACTTTAATTGGATTAGTGTGTATCACTTTGAGTAAACTAATATTGAAGGTTTAAATGTGGACATACCTAGCCTATAAGCAAGAGAGGTCCTTGTAAGTAGACTTCAATAGATTATGAACATATTATAAACTAACGTTGGTCAAAAAGTAGGTGTTCAATGATTCCACCAATACAAACTCACCTTATCATTATTACTCTTAATACACCTTAAAATACGGCGTCGCGTTGGCCAGTGCGCTCATCAACCTCGTAGTCTCGAACTGCTTTGAAACCGACGATGGCTTCTTGGCAACCCTCCGTCCTCCGATAGCCTCCGTCAGAATTTAGCGATTTCCAAGCTCCACATTTTGTCGTCAGACTTTCCCGCCTGGGGACGCCGTGCTTGATTTCGACTCGTGTTGAACATGCTGGTATCACAAAAGTCTGGTACTTCACAGTTCGCCACGTAGAAATGCGGAGTGAACGTAGCAGATTCCGAGCCGACGAGAGACGTTACGATGTAGTCCATTACTCGGAGAGGCGGATTCTGGACATGTTGAATTATATTAAGGGCCCAAGGATAGCTCAGTCGGTAGCGCGGCTAGCATCTGGAGGTCACGAGTTCAAGTCCGCCTTCAACCCCTAGGTTCACCAAGCCTCTATTGGAAAATGGAGCAATCCACGACTGGATTATAAGCCACAGCCTTCGGCTAGGACGTGTCTTAAATTGTAGCCCAGTGGGAGCACCACCAGGTATTGTACCTGTCTCCCAGATCCGCAGATACACTCAAAATAAAAAAAATGCGAGGTGTGTACTGCAGAAGAAAACCTAATATTTAGGCCCCGACTTTTTCTCGTCCACGCATGGAGAATAGGCAACAATTTTGCCAACCAACAGGCGGCCGACATTCTCGGGATCCGCGCGCGTCTGCGCTGCGTTTAACTCTCTGTGGGCGTGGCGACCTGTCTCCGCTTGCTGCGAGTACATTGCGGCCGGAACCCGTGAGATGTCGGCGGCCTGATATTGGTTGTGGTAAAAATTTCTTGCTTTTCCGTGAGTGGACGTGAAAAAGGCGGTGCCTAAATATTAGGTTTTCTGCAGTACACGCCATTTTATTATTTTGAGTGTACTTACGTCGAAGAACGGATCGTCCTTTAATAATTGTACATTACATTTTATTTTCCCTTCTACGACTCGAAAGGGCGCATTTACGCGCGATGGTCCCGCTACCCACCCCAAAAATCAATGGGTGGCGTACCGAGACCACCGCTGGTAAATGCTCCCTCCTTTAAAGTCGTGTGGAAAAAATTGCACAAATGAAGAACCATACTTTTTGTAGCAAGTTTCGTAGTTTTTTGAGTCCGTTTATATAATATCGTAGTTGTCCATTTATTTAATGTGACACTTCTTCCCACTTACTAAGGACTTCTAACACTTATTCCAGTTATTGATTGCAATTAAATCTACGAACACTGGCCACTTCCCTTTCGCAGTTCCTTGTCGATTGCTTGAACGCCACTGGTTCATCGCCCGAAACACACTTCTCTGCACATTCCCTGTGCACCGCCACCGGATCGAATCCCAGCCGGGTCTTCATCGCTTTGAGCTCGTACTGGACTTTAGAGCGTTCGACACATCCCTCATTAGGTCCTTATTCTTTTGTATTTCTCGGAAACCCTGAGCAAATTTGTTGACGTGATGAGATGAAGACGTTTTTTTTGTCACGAAGTTGTGTGTTTACCGTAATTTGATACTTGACTTTTCCAGCATAATGGGCCACGATGAATGCCGGCTCCTTCTTCTGTGGGTGTCTCATAGTATCCGTTGTTCTGGAAATTTAATCATGGAACTAGGCATGTAATAAGAAACATTGAATTAAGGTATGTCCCGGAGGAGTGACCATCTTAGGCCTGACTTAAACTAGAAGTGGATCCAAGTGGCAGACTGGCCTGAATCCTAGTAACAGGCTGACCCTAGATGATTAAAGGTGGATTAGCGCCAGTGGGAATTCTGTATAAACACACTTATAACGATACCAAACGATCGAATATCATAAAACACGCCAAAAACTTTTAGATTTTTCAAATTTCCGGTCAAAGTTTTTGGAACATTGACAAAATTTTGACGCCAAATCTGAGCTGTTGCGGACATCAAAATCAATGTAACATTTTTCTGGTCCCCTACAATGTCTTTTTACGAAAAATTAAAACAAACCAGATTATATAACAAATAGAGAAAAAAATATTTTTTAGTCGAATTTGTGTCACTTTTTGACTGTAAATAAAAACATTTTGAAAAATTTTTGAAAACTAGTTTTATCATGAGATTTGGTCATTTTGGGAGCATAGGTCGAGTGGTTTTTAACAATTTCCACCACCGGCGCTACTCCACCTTTAATCGATAATCGATGCATTTCATACCTTCAAAAACTGATTTAACTTCGCCAGCATTGAGTCGTCTGTTCCATTATTGATATTACTCTCCTCATCGACTAGCCTGAGAATTCCATATGGTTTACTCTGAAAATTCATCTTATATACATGGATATATATATATATATAAATATATAAATATATATATATGCATAAATATACATGTATATATATATATATATAACAGTATGGGAAAGCCATAGGACACCCCCTAATTTGAAGGTTTGAGGAACTTCCGAAAATTTTTTTGAAAAACTGCTAATGCCATTTGTTTTTAAATTGAAAAAAACCTATAGATTTTAAATTTACAAAAAACTTAGGAGGTCGCGCTGGAAAAAACGTCAAAATCCAGTATGAAACTTCTATAGGACCCCCCGTAGGGGTTTTTTTCACGATTTTTCTAAAATCAACTGGCATATTTTGGAATTGACAAAAGCTCAAATCAAGTTTGAGTTAGCAATGAGTTCAGATAAGCAGTTTTGACTTTAAAAAAGTATTACGAAATGTTCTCGTGGGATCTCCAGACTGGTTCTGATTCTTTCGAACTATGTTAGTCTGTTTCAAGCTTCCTGGTGCTCTCGGTAATGCCAAAACTTGATACACACTCTTGAAGAAGTTCCTACTAAAATTCCTAGCACACACACGCTGGCATAAAAATTTTTACGCCATCCCCAAGAAACCAGTCAGAACGCTAACAGCGGATTATAAAGCCAAGTTGCAGTTATTTTTGATCAACAACAGAATATTCATCTACTAAAATCAAGAAAGGATCAATAGTTAATCGTGTTTCCTTGTGTGCGGATGATCTCAAACAGTCTGTCCTCCATTGGTTTGACCAAACTTTTCAGCTGGTTGTCCGGAATAGTGCGCCCAGTCGAGAATTCCTTGCTTCATGCATCTGTTGAGTAAGTCTTGTTCTGGAATAGCATAAACGATACGGACAAGAATCCCCCACAAATTTTCGATTGGATGAGATCAGGACTTCGAGCTGGCCAATCAAGAAGGTTGATCTTGTCGATATGAGCTTGAAATAGTCGCGGGTTGAGTTGCTCACATGGATTGTCGCATTATCCTGCTGAAATCTAAAGTCTTTGCTGGAGTGGTCTAGAGACGAAGATACTTGGAGAGCTCTCTCAGTTCCAAGACGTTCTGATAGTCAGTGCTGTGCATCTTGAACGCTACTCGAACTTCTCAAGCTTCTTCTCCGTGAACGCTCCCCAAACCATCACCGTTCCTCCTGCAAAATTACGTCTCGAAAAAACCCTTGGTTCTTTGCGAAAATCCCGCCGTACACTCGGGAGACTACCGTCAGGCCCATCGAGATTGACTTTCTTTTCATCGGAGAAGACAACCTAAAACAATGATCCTAATTATTCACTCTTGCTTTCTTTAAATTCTCACTTTACTCCAATTCCTTCCCATATTGTTACTTAGCAAATTCCAATCGCTTGGACGAGTTTATGCAGAGAGTAACGAGCAGGGCAAACAGTTTCTGACAAACTATTACACCAGATCGTTAGATGACATTGAGGGTCGAATGGTCCTTTTTGAAGCAGACAATTGAAGCTCATTGCGAATATCTCTTGCCGTCTTACAGGAGTTGGAGGCAGCAGGAATAACATTTCGCTCGCATTTCAGGCACGGCGGAAGAGACCTTTGCGACGAGAAGCTCTTTTAAATGTACCGCGACTTAGCTCACCGGATCCCTCAGATACTCGCGAATACAGTGTCGAGAACGGGAAATTTTCCTACTCCAATTTCATGCAGGGACACATTAATTTCATAACATCCAACTGAGCGCGTTCAGTGTCCGAAAGGGCAGATCGTCGCTCTAGGTGCAAGTAAGACTGCTTTCGAAGTATGCCTATATGTGTGCCACAACACATGCCACAATTCCACAATAATACGCAAAAAATAGTAAATAACATCTGTGAGGGACAATTTAATCTTGAAATATTGTCCCATGGAACCTTGTACTTAGATCAAAGAATAACGATTTGATTCCTGATAAGCGTTCCATTGTTTCGTGCTGCATATTTTGCCAAATCACCTTGACTCCACAGACGAAACATCTAAAGTGCGTGCTAGGTATTTTAGTAGGAACTTGTTAAAGAGAGTTTATCAAGTTTTGGTACCCATTACCGAGAGCACCAGGAAGCTTGAAACAGACTTGAACATCAAAGATCGGAAGAATCAGTTGAGAGCCAGTCTGGAGATCCGACGAGAACATTTCGTATTAATTTTTTAAATTCTGACAAAACTGCTCTCACCTCAATTCTAACTCAAACTTGAACATTTGAGCTTTGTCAAAATTCCAAAATCTGTGTGTGAATACATTTCAGTTAAAATCGTGAAACGGGGGGTCCATTTATAGAAGTTTCACGCGCACTGGATTTTGACGTTTTTTCCAGCGCGACCTCTGTTTTTATAAACTGCTGGAACAAAATCAGTATATAGGTTTTTTTCAATTCAAAAACGAATGGAATTAGCAGTTTTTCAAAAAATTGAACTTCGTCACCCTTAACCTTCAAATCAGAGGGGGTCCTATGGAACTTCCCCACACTGTATATATATATCTATATATCTATATATATATTACGTTTGAAAAAACCCAAAAAGGAAACTTATTGGACTTACCTGAAACAGCTGCACACACTCCGTATTATCAGTATACTCGATATTGGTCCAAGAAATCTCCTTCAAGTACTCCTCTTGTTCTACAAAAAGTGGAAAATATGTTGATTGAAATAGGACTGAAGTTTCTCAGTGGCATCGTTGATACATAACTGGCTTCAAAGCTGTTGCATGGAGACCCAACGTCTTCAAATTCCGAAATATATCCTAGATACTTGAAAATTACTTCAATTTTTAACAATTGATACTCATTAATCTAACCTATATAATATCATGTACCTCCCAGCTTATTGAGAAGTCCTTCTTCAGCAATGCCTTATTAATCCTGAGGATTAAGTGAAACAAAGAGTTGTATATGCACATCCATGGCAGTCTCGGGTGTTGGTGGCGAAATTAAATTATCTTAAATTCTCTAATTTCACTTCTGTATATATATATATATTACCTCAGACACTATATCGCAAAACTACAGTTTCTGTCTTCATAACATGTCGTTTCATAGTTAGAGCCTGCATGGGTGTCGGTTGATGTGAAGCAGATTTGCGACTAAATCCACGACTTCTTCATTTTCAATATACCCACGTTCAACGCGGGCTATGGTAGCCATGTCTCTGGAAAATTGCATGGGAAAAATAAAAAAATTTCAAGATGTTATTATATTAGGAATCCTCTAAACAAGTGTTTTCAGGTTTTTTGGTTTTACGATTATTCAAATTTTTATGATTCGGAAATTATTATAATTCAAATAATTTTCGTCACTATTATAGCCATGTTGTTGAAATATAGAATGCTATCTTTTTAAAGGTGGAGCACCGAAATCTGGAAACTATTTTTAAATGAGTCCAAATTTTCCCGATTCCGAATATCTATGCGAAAAAATTTTAAAAAATTCATTTATCGACTTTTTCAAATTTTTCAACCGGCGAATTTTCGCGCCAGAAACCCCGTGTACACGTGGTATCAGTGTGTCTCATTTTGTCTTGATCTACGCAGATAAAAAATGCGGGAGAAGAGACGCAGAGGGGGTTCTCAACTGAGTTCGCATGGTTAAAAATGTCCTGACATCACCTTTTTTTGGCATTTTTGATCAAACCGGATTTGGAGAGCCTCTAGGCACCACGTGAGTAGGCAGGCATTTTTTGCCTGACTACTTGCGGGTGCCTGCCGTTTTTTTCTCCTCAGAATTTTTTCGCGAAACTCAATAATTCAAATAATTATGAATATTTTCGAGTGAAGCTTTAAAAAGTTGTTTGTGCCAAGTTTGAGTTCGTAAATTAATTAGCAAAAAATGTTCTCACGTCACGTTTTTGGGCAAAAAAATCTCGCATTTTTTGTAGATCAAACCGCAATAGGACAGCCTGGCACCACGTGCGTGTGTCGATTTACGAGATTTGTGTATATTTACGAAATTTTTTATCTTTATCAGACTCTGATTTTCGTTTCTCAACGAGTTTTCTTCATTTTTGTATGTGATTTTTTTAAGGTACATTAAATATTTTATCATCAAAACCCTAGCAAAATTTTTGGTTTTCAGTCGGTAAAATCATATAGGTAATTGCATTTGCCGTCAATTTGTGACCTAATAGTAAGCATCGGAAATATTGCCAGTTTTAAATAATTAATTGACCCTAAAACACACATTACAAAAAAAAACCGATAAAAATTAAAAATTAAATTAATGCACAAATCTAACGACACATGGCTCTAGCGCGAAAATTCAATAACTCTGTACAAATAGCGATTTCAAGCTCAAATATAAAATCGTGGAATTTTAAAAATTTTTTGCACATAGGTAGTCGGAGGCAGGGGAAATTTGGAGTCAATTAAAAATTGCAGATTTTACGGTTTCGGTGGCGCTCCGAAGAACTGTCTGAATAAAATTAAAACTTTGGGAATAGGCAATTATTCGGTATGGTTAACTTTTGCTCTTGGTGAATCTAAACCGTCCCAATCATTTACCTTAATATATGTGATATTGCCAAGAAGCAACACTGCTGAAATAATCCCGAAGAAGGTCTGCTGGGTCTTTGCATGTCCAAAATCCGAGGGAGCTAATTGCATGCCTCAACCTATCAAGCTCATCTCGTACACACCTTCCAGGCAAATGGCTCGTTCTGGAAATTTCATTAATTTTTTTTTAATTTTTTAAACAAAAATCCCTTTGAGGTCAGCGAATGTATCCCTTATTCGCTCCTGTGAAACTTTTCCCAGCTCACCTGATTCAAATACTTATAATCATGTGGCTTCAACAAGAAATATTTCTTCCTTTCTTCCTCGTCTGGACCCTCCAGAAGGTAGTAGCATACGTGGTAGTTCCTGAAAAATATATAAGTCCAAGATGGAAGACTCCAAGGGAGTTTAGGTAATCGTCCGTTCTCCTTTAGTTTGAAATATGATGCGTGATTTTTCCAGCTACCAGGTAGATCTCCACGTTTGCTCTGAAAACTCCAAGTATAAGGCCTTTTTTGTGGTATACACATCAGGAGAAGGCTTCAAATTTTACGTTCGCTAGGTCAATTTAGGTCATAGTGCCTAGTAAGTAGGGTACCTATAAGCTGTGATTACTGCCAAAGTAAAAATTTCCCGATTCCGGCAATTTGTCTGATTCGATGCCAGGCATCCCAATTCCCGCAATTTGCCGATTAGCCAGGCATTCTCAATTCCGGCAATTTTCCAGTTTGCCGGATTGCCGGAAATTTAAATTCCGGCAAGTTGCCAAATTTCTTTTTCGGCAATATACTGGATTGCCAAAATGTTACGGCAACATGCCAATTTGCAGGAACTCATGTTCGGCAAATTGCCGGTTTGCCTATATCCCAGAAATTTTCAGGTCCGGCAAGTTGTTGATTAGCCGATTTTCGGAAATTTCAGTTCCGGCAACTTGCCGATTTGCCGGAAATTCTCGAAACCGGCAATCGCGGGAAATTTAATTCCGTCAAATTACCAACATGCCGGATATTTCAATTCCGGCAATTTGCCAATTTGCCGAGCATTTAAATTCCGGCAATTTGCCGAAGAAAGTATCAATTCTGTTGGCAATTCGCCGGACATTTCCGACAATTTGCCGATTTGCGGATTTCCCAGAAGTTTTCAATTCGGTCAAATTTCTAATTTGCCGGAAATTTCAATTTTACTAAGTCGCCTGCTATCCTCCTAATCTCACCACACTCGGAAACCATTCCATTCTCCCAAATAGTTGATTGTGATGAATTTTCCAAATCTGCTACTATTTTTGTACCGTCGTTAAGGGGACAGCATTAAAAGCCTCTAGAACAGGGCCAGGTGACAGAAGGGGTGTCTGCTAAGTACTGCAGCCTGTTGAACCTTTCGCATGACACTGTTAGCGATATCAAATGGGAGATCAGATGATTCGTGCAATGACCGTATTTCCCGAACCACCCCGGGAGATTACCACGCATTGATTTTTCTTGAGTACGGAGAGAGCATGCTGAAAAACTTGTTATGTGGTTTAAAAATTAGTAGTGACAGTTAGTTAATCCAGCATCTGCAATGTATATCTCTTTTTTTTGAAATCAAAAGTGCTTTGAGGGTGTTGAAAAAACGAACACATACCTGCTAAAAAATTGGTGGCTTCCGAATAATCCGGCCCTTGGCAAATATACAAGCCAATACACAAAGTGAGCACCTACGTGGCCGAGTGAAGAGAAGGCCACCGATTTTTTTGTGGTCACCTGAAACTTCAAAAAGTAACTGGGTTCCCCTGGTAAGAACGTAGAACTCACTTGTGGTAACAGACTTCGGCGATTGCAAAAATGTGCGGTGGTAGTGAGCCGAGCCGCTTACTTTGAAAGTTATCGCCTGCTATTTTGGGTTGTAGATCGGAAAGAAGCAATACGGAGCGGGTACACGCTACTAGAACTGGACCGATGTACGTATAGTAAATATGCCCATTCGCGAATCATTGCATCCCGCAAATTGTCCAAGAAAAGAGGTTTGCTCCGTGAGCTCAACTGGCAAGTGACAGAGTTCGGGGTACTCCCTGAAAAATTTTAAGGGTTTAAAATTTTTTTAAATATAAAAATATTTAAAGGTGGAGTACAGGAAATTTAATTACACCAAATTTTCCACTGACTCCGAATCTGTAAGTAAAAAATTTTGAAAAAATTACCCTGATTTTGTGTATTTATGTTTGAAATTACTATTTTCAACCCTTTGTGCCCGCACCACTTTTTTCAAACTTACGCCCAAAGACTGATACGTAGATCGGGTTTGCATCGTTTGATTTTCGTCGTTTAATTTATTTATTTTCCACGGGGTTGTGGCCCTCACTTCTTCATTGACGGCATTTTCGCGCTTCATTGACAATCGCCTGCCGGACAACACATGGAAAAGTGTCGTGTACTCCACTCGGACAAATCACATCAGTTTTACAACTAAAGAGCCGCGACGCGACACGCAATTCGCCGTAAGCCTACAAAATCTCTCCGACCCAAAATGGCCTAGTTCGACAAAGCAATTCCGATTTATGAGGGAAGCCAGTTTGTGCGGCGAATTAAATTTTCTTGAACCAGTTTCAATCATTTTTGTCGAGTTTTTGCTAGTTTTTTTTTTGACAAAAAAATGAAACTGGTTAAAAAAATTTGACAATAAACAAAATTTTTAAATGAAGGAAATCAAAGCGCCCTCCAATGCGGATTTATTTGGGTGCTCATTTGACATCACAGAAAACACGTGGTGGCAGAGCAAGGATGTCAATGTGAGTCCCGTAAAATTTTCGTAAACGGGACAACGGGAATTCCCGTTCCCGTGAAAATTTTAAAAACGGGATAACGGGAATCCCGCGGCGTTCCCGTGAAAACTTAAAAAACCGGACAACGGGAATACTGCTCCCGTTTTTTTGAAAACACTCAAGAAAAACGGGACAAACAGGGCATTGGTTTAAAAAAAAGAGTGCATAGTTGGCGTATTTAGTGTCTTCGAGGCAAATTATAAAAAAAAACTGCATTATAAACATTATTATCTATTTTTTCATTATTAAACAGATATTTAAAAAGCCAAATGAGTCGGAAAATGTCCCGTTCCCGTGAAAATTTTAAAAATGGGACAACGGAATACCCGTTCCCGTGAAAACAGCCCCAAAAACGGGACAACGGGAAAAACGGGAAGAATTGTACACTGTCCTTGGTGTCGAGGCTGTCTCTTTATCTACAAAAACAGGCTGGAATAGTTTTCCAGAAAAATTCTAACGTCTCTTGACTATAGGGACCAAGCGAAAAAATGTCCGCGTCTCTTCACCCGCATTTTTTGAAAACAACAAAAGAGACCGGGCTGCAACAAATTAAAATCAGGGAAAATTTTTTCAATTTTTTCACATCTAAATTCGTGATGGGGGGGCAAATTTGGAGTGATTTAAAAATATTCAGATTTCGGTACCCCACCTCAAAACAAAATAATGAAAGAATTGCCTTACCCGTGGCTGATCCCAGAAGTTCGTAAGAAAAGCGTCAATCGATGAGGCGACCTCTGCACTTCCAAACCGAGCGCCGCGGGTTGCCGCCCGATAATCGGCCGGTGTCAACATATCGATTTTTTGGAGTGGCACTGTCCACCACTACAGGCAGCCGACCAGAGGCCTGTAAACATCCGCGACTGGGTATGTTTCCCCGGGGTATCCCTAGGCAGCGTTCGTTATAGATTTCTTAGACCGACGGTGGGGCCCATCATTTCGAAGAGGTCAAAGTCTACCGACTGGCCTCCTAGTTCTGGAAATTTTGACTTTAGAAAAGAAATCATTTTTTTCCATTTTTTTTTAATTAGCCCGTTGCTTTTTTAAAAATTAGAAGAAAATGTGAAAAAACTTTGCATTAGAGCGCGTTTGCATTCATTCCATGCAGTCCAATTTTGCTGGGAGCTTGAGTGTCTCGACTTGATCTACAGAGGTCTCTAAAAATGCGGGAGAATAAAATCCACTGATATTGTATGCCTTTAAGAATGTGCTGACGTCACATATTTTTGTGCAAAAAATTCCCGCATTTTTTGTGATCAAAGGCCATGAGGGGACAGCCTGGCACCACGTGAGATTGTGTCGACAATTTTTTGTTGAAGATGTATGGCCAAAAACGGCACATTTAAGTAATTAATCAGCAGAGCGCGTTTGAAATTTTGTTAAAATCTTTTTAAAAGAGTTCCCACTTCCCGAAGTCCTCCGATTTTTCTAAAAACTAAGAGTAGGGAATCTCCGACCCTGAGCCTTCTTTAAAACCTTACCAGCTCTGCCCGGAGAGCACTTTTTCGATGAGTCCTCCGTCGTGCGCCGATCATGAACCTGCAAGTGTACTGTATCATTTTCACAGAGCTGTCGGGATTGAAGCTGTGCATAATAGACGGCTAACGTATGTTGCATCGACTGTCGCGTTGGTGAGCACGTTGGGGAAAACACCCCGTCGCTCCAGCTGATATTGAGTCAAATGACATCATTTTAGTGAATCCAGCATCGGGATGAATACGTCTGTAAAAAAAAATTTTTTTTGAAAGAAAAAGTGCCTGGAGAATCAGGCAACGAACCGGACAAAAACACAAGACCGCGAAAAACCAATTGGTGGCCGAGTTTTCTCTCTCGCGGTCACTTAGGAAATACTAAATTCGCACGGATTTCTGGCTTCTCTCCAACATAAATTGAAATGGAAGATTTTCGGCCGAACTAGGCTAACTCCGGGCCCTATCTGGTGTATGTTTCCGACTTTCCCACGGAGCGATTGTCAATGGAGCGCGAAAAACTCACTGAGAAAGGCCCCCCGTGAGATCGAAATGAAAATTTGCTAAATGGCCGAAAATTGAATACTCGGCCGCCAATTTTTCGACACGGCCACAGGATAAATCGTAAAAAAAATTGAGAGAAATTTATTAGAAAAAATCTGAAAGTAATGTTTATTGCACCGTGGCCGCAATTAATGTAAAAACACGGCCACTTTTTTAATGTGGGGAAAAGGTTGGCCGAGTATTATACAGTTTTTGCGGCCACTTAGAAAATATTTAGATCGAAGGGAAGTTGAGAAAATACGTCTAACGAAAACCAGTCAATTTTTGTTACATGACCGAAAAATGAAAACTCGACCACGGATTTGTTATGCTTTATAAAAATTTATGAACCTATTATTTTTTGATTCAGAAATCTTTAGAATTGTAACAAGAAAAAGTCGGCATCTTTTTTTCTCACGGTCGCAATTTTCTTTGTGATCGTAAAAATGGAAGCTCGGCCATGGTGGCCGAGTCCCTTTTTTTTCGCTGCCTACTGGTAACACGTGGTTGGGTGAAGAGAAAACTCGACCACCGGTTTTTTTTGTCACTGAAATTTTTCAATTTCAAAATATTTTAAATCTTGCTGCACTCTTTCAGCACAACCGCGAAAAAATGACAGCTCGGCCACCAATTTATTTATTATCTGGGTGAAAAAATTTTGTTAGCCAAGTTTTCTTCATCTGGAAATCAAAGAGATTTTTGTTACGTGGCCGTGAAAAGGAAAACTCCGCCACCAATTATTTTTAATTTCAGGCACTGGCGTTGTAAAATCTTATAAAAAAACAGGTTTTTAAGTACATTGAACTAAAAAATAAGGAAGATTTTTGGAAAAAAAATTGCTGGCCGAGGAAAACTCGGCCAACAACTTGTTCCGGTCACACAGCAAAATCTCTCGATTTTCGATGATTGAATATTGAAATCTGGGTTGGATTTTTTAGTATCATTTCATTTGGTCGCCGGTGGAGAAACGAGGGAGAGAGAGAAAAAAGATTTGTAGTGTCCCGGGAATCTTCCTCAAGTGTTGTGGAAGAAAGTGGAAGAAGCTTCTGCGCAGCAGCAGCAGCGTGGAAGTGGTTCACGAAAGAGAGAGAGAGACATGTTGGACTTGAAACCAGCATGATGAAAAATAAGAAGATGAAGAAGAGAATTACACACTACCTCCACAACACAGATTATTTTTATCACGTTTTGAGGGGGCGCTTCACACAATTCATGGCCTAGAAATTAAGTGGTAATTTGGTGGCCTAGAAAATACTATATTTATATTAATTATTCTACGTCAATAATTTAAACGGGAAACGAAATTTATTTTAAAAAAGCCATAGAAGAGGTTTTGAAATTGGCTAGGAAATGAAAAATTGTGTTTTTGGAATTTTCTAGGCCCATTTGAACTTCTCCTGAACACTGCGCTTTCAAGACTTCGAATTTGAATTGTGGCCTAGAAAATCATAAAAACTAGGAAATCAAGAAAAAAACATGGATGAAATTTTGAATTTTATAGGTCATTTGAAATTTCTGGCCTAAAAAATGAAAAATGATTTTTATTTTGAATTTTCTAGGCCACTTGAATTTCCTGACGTCGACAATTTTCATAGCCTAGAAATTTAAATGTGGTGGCCTAGAAAATAATTAAAAGTAAGTAATCGAGAAGAAACGCGTGAGATTCGGAGTTTTGTATTTTCTAGGCCATTTGAATTTGGTGTTGGACATGAAAAGCCAAAAAGACTTTTCAGGAAATTTCTAGGCCATTAGAAGTTGATTGGCCTAGGAAAAAATTTGTGTTTTTGGCATTTCCGTCTCTAGGTCATTTGGATTAGGGCCTAGGAATTGAGTAGTTGTTTTGGAATTTTCCACCCTAGGCCATTTGAATTTGGTGGCCTAGGAAATGAAAAAAATATTTAAAGGAATTTTCTCCATTGAAGTAGATGGCTTGGAAATAAAAAAAGGTTTTTTAAAGGAAATGTCTAGGCCCTTGAATTAGTTGGCCTAGGGAATGAAAAATGATTTTTTGCTTAAAATTTTTTAAACGCACTTGAATTTGGACGGCCAAGGAAATGAAAAATGGTTTGTTGAGTAACTTCTACTTGAATTTGGTGACCTGGGAAATGAAAAATGATTTTCTTGGAATTTTTTAGGCCACTTGAATTTGACGGCCTAGGAAATGAAAAATAGTGGTAATTTCTAGACCACATGAAGCGATTTTGGTGGGGAAATGAAAATGATTTTCTTGGAATTGTTTTTAGGCCACTTGAATTTGAGGGAGGAAATGAACAACAGTTGTTTTGGAATTTTTTAGGCCACTCGAATTTGACGGCCTAGGAAATAAAGATTTTTTTGGTAATTGCCACTTGAATTAGGTGGCCTGGGAAATGAAAAAGATGATTTTCTTGGAATTTCTAGGCCATTGAATTAGGGGGCCTAGGGAATGACTCCAAAAATTATTTTCTTAAGATTTTTTAAGCCACTTGAATTTGACGGCCTAGGAAGTGAAAAAAGGTTTTTTGGTAATTTCTAGAAGGCCACTTCAATTTGGTGACCTGGGAAATAATGATTTTCTTGGGATTTTTTAAGCCACTTGAATTTGACGGCCTAGGAAATGAAAAATAGTTTTTTGGTAATTTAGAGGTTGAATGTGGCCGTGGCCTGAGAAATGAAAAATGACTTTCTTGGAATTTGTTAGGCCACTTGAATTTGACCGGCCTAGGAAATGAAAAACTGTTTTGGAATTTTTTAGGCCACTTGAATTTGACGGCCTAGGAAACGAAAAATAGTTTTTAGGTAATTTCGAGGCCAATTGAATTCGGTGGCCTGGGAAATGAAAAAAGATTTTCTTGAAGAATTTTTTAGGCCACTTGAATTTGACGGCCTAGGAATGAAAAATCGTTTTTTGGTAATTTCGAGGCCATGGCTAATTTGGTGGCCTGGGAAATGAAAAATGATTTTCTTGGAATGTCATTTTTAGGCCACTTGAATTTGACGGCCTAGGATAGTTTGTAATTTCGAGCCCACTTGAATTGGTGGCCAAAATAATGAAAAATGATTTTCTTGGAATTTTGACCACTTGTGATAAATGTGACGGCCTTATTAGGAAGACGCATGAAAAATCGTTGGTAATTTCTAGATCGCGAATTTGACGGGCTAGGAAATGAAGTTTTTTGGTAATTTCTAGGCCACTTGAATTTGACCGCCTAGGAAATGAAAAATACCAAGGTTTTTTGGTAATTTCTAGGCCACTTGAATTTGGTGGCCTGGGAAACGAAAAATGTTTTTCTTGGAATTTTTTAGGCCATGAATTTGACGACCTAGGAAATGAAATTGTTTTGGAATTTTTTAGGGCACTTTTGGGTTCGCCTAGGAAATGAAGATTTTCTTGGAATTTGCGAGGCCAGCAGACTTCAATTTGTTGGTCTTGGGAATAATGATTTTCTTGGAGTTTTATAGGCCGCTTGATTTAAGCCCATGGCCTAAGAAGTTCAAAATAGTTGTTACGGAATTTTCTAGGACATTTGAACTTGGTGGCTAAGGAAATGAAAAACTTTTTTGGAATTTTCTAGGTTTCTGTAATATATGATTTATTCAGTTAAAAAATTAAAAAACATTCAATTTTTTTTAAATTTCGTGTTAAAAAAAATCAAATTTGCCCAAAACTTAAAAAATAAGCTAAAAAATTGTAAGACGATACAGAACGGCAAAAACTTGAAAATAATAAGCGTGATGAGCCCTGTCGGACGTAAGGGCCGCCGGCTGGTTCGACCTTCTTTTTCTCTTTTTGTTACTCCTCTCCCGTCCCGAGCAGGAGCAACACAACGAGAGCGCACAACAAGAAGAAAAAGCAGATAGATATACTTAGATATAAGTTGTCTTCTGTTCATATTCTTTCTTTTAGACATCTTTTCATTCGAAACAACACTCCATTCTCTTCCGTTGGACGGGGGGGGGGGGGCGACGCGGGAGACGAAACAATAAAGCAAAATTGGGAGGGGTTGGAGAATGTTTGGACAACAAAAAGATTGACTGATCAATCGATTCGCCAGCCTCGGCTATTTTCGGAAATCGGAGCTATGCAAATGCGCCCTACTGATCAAATGGACGGGTGTCATTTAAACTCCTTGGTTAAAAAGCAACGCAAAATGGCATAGTTCCAGTTTGCCGATTTGCCAGAAATTTTCAGGTACAGCAATTTTCCGATTTGCCGATTTGGCGGAAATTTCAATTTAGACAAATTGGCGGCTTGCCGAAATGCCAATCCAGGTCCGCCAATTTGCCAATGTTGATTTTTGGCAAGTTTCTGGTTAGGCGTTTTCATTTTCGAATTACCGTTTTGCCTAAACGCCAGAAATGCTAAGGTTCTCTAAAGCGCTGGTTTTTCCCGTAAAAATTTTTCATTTTCGGCAAATAATTTGCCGGCTTCCCAAAAAGCCGGAATTTTTCAGCCGGCAATTTGCTGAATTGCCGGGATTTTTTTTTCTACAAATAGCCGGTTTGCCGAAACGCAAGAAATGCTCAGAACCTTTGCCGATTTGCCGGATATTTTGATTTTCGGCAAATTGTCGGTAGTTGCCGATATGCCAGAAATGTCTTCAGGAACGGCAATTTGCGGAATAGCCGGAATTTTTTTTTTTTGGCAACGATTTGCCGAAATGCCAGAAATGTTGCGGTCCGGCAATTTGCCGAAATAAATGTTCAATTTCGGCCAATTTGCTGATTGCCGGAGTTAAACAATTTCGGCAAATTGCCGGCTGGTCAATGATGCCGGAAATTTTCAGGTCAATTTGATGATTTGCCGAAAAATTTATTTAAAAAAAAAATGTACCTATTTTTCTCCAGACAGGAAGTCTCTAAAATCTCATTTAATAAGAAGAAACAAAAGAGAAACAGAGAATGGCCTAACAAGTTTCGAGTTACAGAAACCTAGGCCACTTTGAAGGCACCGGCGTAGCCTAGAAACCCAGTTCCACAAAAATAAGAAAAAATTAAAACTCGGCAACATAATCTAGGCCCGGAGCATACAAACACTCCACGAATATTAAAGACTCTTTCTAGGTTACTGGATACCGTTAACGATGGAAAACTCGGCTCGGCCATCTGCGAATTTTGTTGCTTGAAAATGGGAAAAATAAAGTTTTTTTAACTTACGGTCAAACAAAAAAGATCAAAAAGTGAAAAGCGGGGATTTATCTTATCACACAATTTATGACATAAATCCGTAGGCCGAGTAGCGGAGAGATCTCGGAGCTCAATGTTAGGAATATCTATTAGGACGACACATCATACTCAGCCACCCCAACCCAGTCATCCCACCGTTGTCCACTGTCTTTTTTTTTCGCTTTTTTATTATCAACCAGCAATAACTTATCGCCTTTATCTTTGTGAGGCCCCGCGCAAGAACGAGACAGAGAGAGAGAGAGCGAGAGAGTGAGAGACAGAGACGCCGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAGGGATATAGGTGCAGCGGACAACTAGACGTCACTGGGCTCTTTCACACATGTGATATTGAACGATAAATTGCGCTCCTAGGCCACAAAAAAACAGTGTATTCGATCTCATGATATGGGAGAAGCTGGCACCGTGCCAAGTTTCAGAAAAAATATGGAATTTTTGCTTGAAGCATGGTGAATCAACGTGCTTACACAATTCTTCGGGATAAATATTCCCGCATTTTGTAGATCAAAACGCAATGAGTCATGCTGATACCTGAGGTTAATTAAAAGTACTGATCGAGATTTTGAGCGTCATATGGTGTATTTACCGGCAAACCTGATGCGCCTGATTTGACGCGCAAATCCTTCATTTTAATAAAGTTGGGCTTCAAATGTGATGCCTCAATTTCTATTTTTTGAAATGTTTTGATTTCGTGAAAACTAACGGCGAATTTCAGAAAATTTATAGAAAATGTTCATTTGTTGCGACCAAAAACTTAAAAAAGACCAAATCAGGAAATTCACATTTTTCGCCGAAAAAACCATTTTGCGCGTAAATTCTGATGTAATTTGCCGTAGGCTATTACGTGTGAAAACACTGCCGGTAATACGTTATATGCTTGAGCGCACCCAAACAAATCTCGTCCCAAATTATTCCGGTTGCACAAAATTCTGAGAATGCGTAAAGCGCAACATACCTGACGCGCAAAATATCTCGAAGTGGAAACTACAGTAATCCTTTTCAAATGATTACTGTAGCGCTTGTGTCGATTTACGGGATCTCGACTTTCGAAATGGATTTAAATATATTATTTATCAATAGAATATTTCAAAGATGAAGAAGTTAATTTCGTGAAGCCCGTAAATCGACACAAGTGCAATAGTAATTTTAAGAATTACTTAGTGTTTCGCTACGAGATAATTTGCGCGCTACTCAAATATGTTGTGCAGTACGGGCATTCAGAATTTTTCGTTCCCTTTCACAAAAATCTCATCGATAAACTTGCGCGTAAAATTTGGTGGTGCCTGTGAGTGGTTCACCTATACAAGTGGTGCCAGGGGCTGTCCCATTACGGGTTGATCTACAAAAAATGCGGGATATTTGCACAAACCATGCGATATCAGTTGAGAACTCTGCGTCTGTTCTCCCGGATATTTTGTAGATCAACGTAGATCAACACTCTGACACGCACGTGGGCCGAAGATGTAAGTGCCAGATTACACGGCGCAAAAACTGAAAAAAAAAAGAAGCGAAAACTGTCAACGAGCATTTGAGCGAGTTTTTTATCATCCACGAATCACAAGAAAAATCAATAGAAAATCGATAATCAAAAAGTGAGTATCATATTTTCGACCAACAGAATCATTCCAGGTTCATCAGTGAGCATTGTTTTCAAGTATACGATGAGCCAACGACGGACACGTCCCGTTCTCTGCCACAAGTTCGCCAATCTCTTGAATAGGCGAGTAGCCCATTTTCGAGTATTTATCGATTGCGGCAATCGGATCATTAACGTTCGAGAGCACGTCGCTGAGCATCCGACAGCCGATGATTGTTTTGAGCATTTCACCAATCCGTGACGATTTCCGAGCGACTTCCAATCACAATTCCCAAAAAATCATCGGGGTTTCATGCTTTTGATTGATCTACAAAAGAATGCAGGAATTTTTTGCCCAAAAGATGGTTATGGACATCGTCAGCACGTCTTACTTTTAACCATGTGAAATCAGTTGAGAACTCTGAGTCTGTTCTCGCGCATTTTTTGTAGATCTGCGTAGATCAAGCCGAAGTGAGACCTTCTGAGTCTTGACACGACAAACTCCCATTACATACGGATGCTGAGCCTTTGTTGGATGTGAGAGAGTTTCCAGGTTGTTCTCGAAACTTTGCTTAAAATTTCATTCATAAAAAATCATTTTTTAACGAAAAACTACTAAAAATCATCCGATAAACCTGGAAATCCATGAAAAACTCTGTGACAAATACAGTACTGTTTAAAGGCATAGTGTACCCAGTCTGTGTTCTGAGAATACGTATTACACAACATATTTGACGGGCAAAATATCTAAAACCGTCTACAGTAATTCTTCAAATGACTACTGTAGCATAGGCGCTAGTGTCGATATACGGGTTCGGCTAGGTTTAATTTCTTACGAAAGCTCGGAAATCGACACCACCGGTACAGTAGTAATTTTAACGGCTGAATTACTAGTTATATTTTGCGCGTCAAATTTGTTGTGCTGTACGCAGTCTCAGAACTTTGCGTTTTCGTGATTTTTTTTTTCAAATTTTAACTGCGGTAAAAAAATAAAACAACATAAATTTCATTTAAAACAAAAACGATTTTACCGCTCTCCGCTTTAAAGGCGCACACCCGTTTGTGGATAGTGGTTTAAACAAAAATATCGCGTCGAGACCAGATTTCTGCAGATTTCGCGCCAAGACCCTACCTTATCCCCCTGATACTGTAATTTGTGGCCTCCTGTCCCTCCTATGCACCACCACCACCGCCCCCATCAAAGCGGCGAGCTTCTTCTTCTCCTGTCTCGCCAAACTTCTCAAGTACTGAGGAGTGAATGGTGCCAGCGCGGCGATCGTTTGTATCGGTTTGCAGAATTTGTGCCACGATGTTGCTCGTAGATTTGCAGCGATAAATTGTGCAATTTCTTCTTTTTCGCAATTTCTGCCCTGCCGAATGAGACGATGAGGACTGTGCAGCGGCCACCGTTTTGAAATCCGGATTTTTGCTGGAAAGATAAAATTTAAATAATGAGGAGATTTTTTTCTCGCAGCGATTTCTCTGGACCCTGTTTATTCCCAATACGGTTTGATCTACAAAAAATGCGGGAATAAGAAAATGTTTGCCCGTTAAAATGCTGACGTCAGCAAAGTTTCTGTCTTAACGCTGCGAAATCAGTTGAGACTGCGTCTTTCTCCCGCATTTTTTGTAGATCTACGTAGATCAAGCAATGAGAACCACACTATGAGTGCAAACACTATCCACAATACATCATATTTGACGCGCAATCTTTAATTTATTTTTTGCGAGACCAAATAAATCTCAAACTTTCCACTGAAAAGGATTTTCATGATTCATTTTAAAAAAGTTGCGCCTCAAATGTGATGTGCCTGAATTTTCGCTTTTTTGAAATTTTTACTCCTATTTCGTTAAAAATGAAGGAATTTCTCGAACATTTATAGAATTTTAAAAATTTTCATTTTGGGTTAAAAAAATCGAGTTAAAAAACAACCATAAATTCAGGAAACTCAAAATTTTCTCCGAAAAACTTTCCCCATTTTACGCGTGAAATCTGGTGTATTTTACATCCGTGCCTAGGCTGTGTGAGAACACTGCCCGTCATACATTATATTTGACGCGCAAACTGCAAAAATCGTCGGAATTATTTCGGGAACAGAAAATTCTGAAAATGCGTAACGCGCAACTTATTTGAAGCGAAAATATCTCGTAGCGAAAACTACAGTAAACTTATGTAACTGACTACTGTAGCGCTTGTGTGTCGATTTAAGGGCTCAGTTTTCAAAAAAACGAGATCCCGTAAGTCGAAAGTGCTATGCAGTAGTTGCTATTTCAAGAATTACTCTAATTTTCGCGACGAGACATTTTGCGCGTCAAATATGTTGTGCAATGCGCATTTTCAGAATTTTGTGTTCCCGGAATAATTCCGACGATTTTTTGCAGTTGCGCGTCAAATATGATGTATGACCTGCAGTGTTTGCCCACATCGCCTAAGCACGGTAAAATCCGCCAGATTTTTCGCGCAAAATGGGATTTACGGCGAAAAATTCGAGATTTGCTGAGATGAGTAGGTCTTTTTTATTATTTCTTAATCCAAAAAAAAGTATTATGAAGATTTTTAAAGTTTCTATAGATTTTCTGAAATTCTCCGTCGTTGTTAATAGAAAAATTTCAAAAAATTGAAACTTCCGCCAACATTTGACGCGCAACTTTTTTGAAATGAAAAAGCCCGAATTTTCTGGGAAATTTGAGATTTATTTAGGTCTCACAGTGAAAAAAACATTAGAGTTTGCGCGTCAAATATCATGTATGACCGGCAGTTGCCCACATCGCCTAAGCCCGGTAAAATCCAGCAGATTTTTCGAGACTCGCAAAATGGTTTCGGCGAAAAATTCGACTGAGAATTTTGGTTTCGTTTTTACTATCTTTTAATCCAAAAAAAAATGAAAATTTTTAAATGTTCTATAAATTTCTGAAATTCACCCGTTTTTCAAATAAAAATTGGCGCATAAAAAACTTACACGATAAAATCCAAAACATCAGATTTTACGAACTGTTAGCAAAAAAATTGATTTTTTGGTTTTTTCGGGCTAAACATTAGAAAACCTCCAAGACTATACTCCAACAAAATTTTTTTTCAGTTTTTTTTTTGAAATTCTTTTTTTTTCAGTTTAAAATGTTTTCATCGCTTTGTTCGTGTTTTTGTTGATGATCTTGTGCGAAATTAATGATTTCCATATTCAACACTGTTGTGTGATTAATTTAGTACGGATAGATACACCGTAACTATTCAGCATGTTGAGTTTAGTTTTCGTCGTCCAATTTATCAAGGTTTTTTTTGATTTTCAGTCAAGTCTTTCGCGCTTACTTTTCTAAGCAGTAATGACCATCGCATGATTGCTAAGGGGTGCTTTTAGTGTTTGGTTTACTTCTGCTATTTCATGAGTCACTCCTTATCACTAATATAAATGCAGCATAATTCCCGAGTGAGCAAGCCGCGAGTATTAAATCACAGAAGCGCTGTTTTAAACTGATGATGATTGCAGTCTCCTTCATTGTTCTGACCGAAGGCTACCATTTTTTATTCATTCCCAGAGTCTCCTGACAAGTGGAAAGACAACTAAAAGCTATGTCCGTCTCGGACAAACCCGCTGCCCAATCAGGTGCCAAAAGCTTGGTACCGCTCCGCGCGCTGAAGAAGAGAAATGAGGAGTGGGGAACCAAGGTCAATATCGATACCAACATTCGCAAATTGAGTAAGTTTTTATTTTAAAATTACCAGTCGTTCGAGCTTATATATCAATTTTAGCGATCAAACCGACTCAGCGAATTTGTATACAAGTACGCTGTGCAAGTGACGTGTTCCGGAAACCTGATGGAACTGAGGCGACAATCTAAATCTCCAAATCAGGCAAAAAGGGAACGGAGCACGAGAACGACAAAACACGCTGCCAGAACGTTTACAATGAGGCGATCAAGCGTTACGATGAGCTGAAAACGACCGTCTTTCTACGATCGTCAAGCCTCTTTGTACACTTCTGACCAAATTGAAGAAAGGTGAATTCGATTTATTGCTTAAAGTTTAATATTTTAGCGTTTCAGAGCATCTCTTTCGTTGTGTACCGACAAGATTTGGTTCCAAGCGACAAAACTTCAAAGAGGCCAGTTTGTTCTCAAAAAGGTGGATACTATCAATCGTTGCAGTCAACATCGAATGACGTCATCAAGACAATCGTGCCCAGCCAAGACTGCCGACAAAACTTTGCTTGAGGCAATCAACATCATTGTCTCGGGTATGACCCCAGCGTTCCAAAAGAATGCCGCTTTCAGAGAAATCAAACGGCTATTACATCTCGCGGCAAAAATGTGAGCATATCACCGTTGGAGCATGCGTTCATTACCTCATCGACCCAACTGTAGTCGAGTAAACTGTAAGAAATAATCATATTAGTATTTAATTGTTTTTTCGCGTCGCGTACAAGGAATACACTGAAGGACATCTCTACTCAAGAGTCGGTGTTTCAAAGTCGGTGAAGACACAATTTGGCAGGAACGGCAAGAAAGTTCCATCACTCTTCAAGTGAAAGTTAGTTTTTCAGAAAATCTAGATTTTTTTCAAAATGTTATAAAATTGATTTTGAATGAAGACAACATTGTTCCCCGGTTTATGCCCCACTTGTGGAACTTTTGCAAACGTTCAGAAGTTTCACCACCTCTCAAAGCGAATGCTCCAGCCCTGGCGCAGAGAATTAAGCCTCTCTGTTGGACTGGTGTTGTCTTGAACTTTACGATGTGCACAAGGCGTCTCGGAGAGGATGGTGTCGTTATGAAGATCCGTCGATTCCACACGTCAGCTAAGGAGACATGTTTTGAAGTTGAGAAGTCAACTATTCACGAACGTCTTTGACTTCTTCAAAAAGAAGTATTGAATCACTTTGAAGTATCCCGATTTATACACCATTGAAGCGAAAGGGAAACAAGGCAAAATTCATTTCCCTGCGGAAGTTCTCCTTTTCTGTCCGAACCAGACAGGTCACGAATGATCAAACCCAGTGATCAACAATGAGCAGGCGGAGATGATTAAGGTAATTTGATATTTTAAAATCTGAATAATATCCCGAAATTTCCTTTTTCAGAACACCCACATATCAGAAAGACGACAACTGATACTATCGTGAGAAACGTCAGATTGGCTTCCAACAATATCTATGGCTTCTTCAAAGTTGAAGACCCTGTCAACCTTGAAGGAATGGTTCTTCCAAAACCTAGCGTTTGCCGGTAACCGACTCGCTGATTTGGAAAATCCGAAGTCTAGACCCCACCGACTTCAATCGTGCTGGATAATATTACGATGCCAAGGAATTGACGAATTGGGAACTGGTCTTTGTTCAAAACGACGAAAGAAGTCCAGTAAGTTTCAGCTTGTAATTTTTCATTATATTGACTCAATTTCAGTTAGGACTTGCTACGCAGCCTATCGCCGATGAAAAGGTGACTAAAGGTATGAAATAGCAACCCAACGATGAGTTTCATCATTAGAGGTGATTTGGAACGAATCGTCAAGAAAGCGAAGGCTGCTACGCAACTTCTCTTGTTCGTTGACAAATCTTGTACCATTTCAACTATCATAAAACTGCAAATCAAGGCGTTGGAGCGTATGACCTGCTCACTCAGCAGATTCGCGGTGAAACCGCCAAGAAAGTCTGCCGTAAACCAGACACAAACTCGTCTTAACATTATCAATAAGACAAAGCATGAAACTCGGAGGACTGAACTATGCTAACTACTTGTGAGTGAGGCGTTCAACAAGCCAAATAGAATATTGTCGTTGGATTTGTTACTTCTCAACGGGTTGGTGGAAATCCAGATGTGAGTCATGACAGCTGCACAATCATATTTCATTTTCTCCAGTATCCAATATCAGTTGGATTTGCTGCAAACATGCTCCGGCAAGCATCATCAAAAGTTTGCCCTGGTGGATACGGGTATGTTCATCGCGATAGGGATGTTTTCGCGATCCATCAGGCATAGTCCAAGGATCTTGACTATCTTCGTGCAAAACATGCACTGAGCAGCGCGGAAGACCAGATGGTATCCTTTTGTATTTCAATGGAGTTTCCGAAGGGCAATCACAATGATCAACGAGGAATTCAGTGCCCGAGTGAAGGAGGCGTGCATGGCATTCCAAAAGAGAGGGAACCGCCATTCAGACCACACACCATCATCGCCTAATCAAAGGCTCACAACGAGCGTCTGTGACAACAAATCCGAAAAGGGACGTATTGTTAATTTGGAGCCATGGGGGTACTGTCGTGGACCATACCATTGTGTAGCAATATCTACATTGAGTGGTATCATGCCTCAGCTGTAGCGCGCCAACAGCAGAGGTTACCAAGTTCACTCTCATCTTCACCACTAAAGCCGGCCCACAAGCTGAGCCATTGTGGCATCTCGGTACAAGCAATTGACCAATGATCTTTGCATCATCAGATTGTCTTCCATCCGGTCGGACTTCCCGTCCCACTGTACATTGCTGATCGTTACAGTCAACGTGGAGCAATGGTTCTTGCCGCCAATCAAGGGTAAGTTAAAATATATACGACATCTATTTATTATTTTCAGTCCACTACAATGAAGGACAAATCGATCTCGCGGCTACCAACAGTGCATATGGCTACGGAGAGAAGAAGCTCTTCACCCCCTACTCGTTTCAATGGAAAATTATCTGTACTTTCCTCTGTTTCTTTTACTCTTAGTGGCTGTATAATGTTTTATTTCGTCAACCCAGACTACTTTCGCTATGATTGTATATTTTTCAGCATTTGGTCATTGTCATTTGTAATTATTGTCGGAATGAGATAAAATGATTTATGAAGAATCAAATGCATCGCTTCTTGGTCAATTCCTGTTGATAAGAATCTCATTCAGATATTTTCAAAAGTTGTGGTTTATTGATATTAAAAAATATCCACGTTGCACGCTGCTGGGTCGCTGTGACTGGAGAAGTTGATGTTTTATGAATTCTTCCGTAAATTCAGCTGTTTGTACCTGTTTTGTAATGTTATCACTTTCTTTCGAACAAAATGTCGATTTTTCTGGCAGAAAATTCCACTTTTTAAAATTATTTACAACATTACAGATGGATACCTTCTGTTGTGTCTCGATTGGAGAATGTTACGAATCGAATGGAGAATGTATTGCTGAAATACGACTCGAACAAAGGAATTAAATAATTGTTCTCGAAATTATAAATTTCAAAATAATCGCTCTTTAGAAACTCCGGTCGGCGCGACGCCTCAAATCATTAATCTTAATGATGATGTGATCTGTAAGAATCTCGTCTCGTTTTATATTTATCTGCCAAAATAGGAGGAGATTTGAATCGCCTTGGATGCATGATAAGGACATATATAATATTTAATTCAAATTTTATCGAAAATTATTCAGTCTAAGAATCTATTTTTCAAACGCTTTTTTCGATGTTGTTTGTGGATTGCAGTGTGGGCGCAAAAACGCGAACACTACGACGAGTTCGCGACTCTTGTGAACGATTTGACGGCGGAAATTGTTGCATTTTCCGATTTCAAGGAGAACCGAAAATCCGAATTCTACTATAATTATATTTGTGGACTTGAAGCTGCTAGGTGGGACTGGTGGAAATTTGCCAATCCTGAGTCCGAATATCTATGTGAAAAACTCTTCATTATTTTATATATTTCAGCTCGAAATCGCATGTTCATACTTTTTTCAAGCACACGCCATATTCTCGTCGCGCCGTGTTGTGTCAATTTACGAATTTACCAATTGTTTTCCAATTTAGTTTTTAAACGAGATTTTTGTGGGCTTTATTTTTGTGAGTTTTGTTTGGGTCAAAAAAAATCTTACAAAGAATCATAATATCCTTTCAGGAAACTCAAATTCGCCGAACAACTACCCTATTTTGCGCGTGAAATATGGTGTATTTTACCTAGACTATCTGTGAGAATAATGCCGGTCATTCATCATAACTTTGATGCGCAAACTGCAAAAAACGTCGGAATTATTTCGGGAACACTTCTGAGCGGCGCAACATATTTGACGCGAAAAATACCTCGTAGTGAGAACTACAGTAATTGTTGCGTGTAAATGACTACTGTCGAGAATCGCTGTGTCGATTTAAGGGCTCATCGAAAAATAGAGATCCGGTTAAACGACACAACTGCTATAGTATTTGAAGAATACTTAGTTTTCGCTACGAGATATTTCGAGCGTCAAATCTGTTGTCAATGCGCATTAGAATTTTGTGTAAAAAGTTTTGTGTTTAGTGATTTTTGGAGTTTGCATAGCGCGTCAAATATATGACCGGCAGTGTATGCCCATCGCCTAAGCACGCTCGGTAAAATACACCTTTTCGCGCAAAATGGGATTTTCGGCGAAAAATTCGAATTTCCTGAGAATTTTGGTCGGTTTTACTATTTGTTTACAATGCAAAAAATGAAAATTTTTAAATTTTCTGAATTATCGGCACCGTCGTTTTTCACTATATAAAAAAATTTCAAAAAATTGAAAATTCCGCCACATCACACTTTGACGCTCAACTTTTTTTACATGAACAAGATCCGGATTTGTCTGCGGGGAAATTTGAGATTTATTGTGTAGGTCTCGCAGCGAAAAAAAAATTAGAGGTTCCGGCGTCAAATATGATGTATGACCGGCATGCACATAGCCTAGACACGATAAAATACATCAGATTTTACGCGCAAACTGGCAAAAAAATATTTTTTGGCTTTTTCTAAACATTTGAAAAAATGGATAGATATTCCAACAATTTTTTTCAGTTGTGTTTTTTTTGTGAAAAATTCCTTCTGAAGTTCAAATAAATATATACTTTTTTAAAGTTCGAAAAATTCACATTAGCGCGTTAAAAACGACGTAGTCAGGCATCACATACATTTGACGCGGAATCTTTTTATACAAGAAGGATTTGCGCGTCAATCTGGCGAATTAGGTTGTCGGCGGAATACACCGGGCAAATTTCACGCGTAAAACTTCAAACCCTGTTTCAATAATAATCGGAAAGAGTATTCGAGGAAATTACGTCTTTCAACGTCTCCGCTGGAACCACGACAGCAAGTTTTGTGTTGACGGAAAAAAAACAACATTAAATTTTTCGACACAAAAAATTAAATTTTTCAACGAAAAATAATAATTCTAAATTTTACAACGCAAAAAAAAATTAAATTTTTCAAATAAAAATTAAATTCGATTGATTCAACAAAAAAAAATTAAATTTTTCACCAACAAAAAATGTAATTTTTCAACAAAAATAAATTTTTTAATGAAAAAAAATTAAATTTTTCAACGAAAAAAATTAAATTTTTCAACAAAAAAAAATTATTTAAATTTTTCAACAAAAAAAAAAGAAATTAAATTTTTCAACAAAAAAAATTTAAATTTTCAAAAAAAAAAATTACTGGAATTTTCCAACAAAAAAAAATTCAAATTTTTCAACAAAAATTAAATTTTTCAACAATAAAAAATTAATTTTTCAACAAAAAAAATTAAATTTTTCAACAAAAAAAAATTCAAATTTTCAACGAAAAAAAAATAAATTTTTCATCAAAAAAAAATTCAAATTCCCGCGGAAAGTGCAAAAAATTTACAGAATATTTTCAAACCCCTCGCTTTTTCACTTGTCTCCCGCTATCATCTTCACGCAATTCAGCCGACACCTTTTCGTCGCCATTCGATGCGGGTTCCCAGCGATGTATCGATTTTCAGTTGATTAGATCGAGTTTTCGCTCCACGTACAGTACACTGAGTTCTGCTTCGAGGCCATCTGAAATTTTTTATTTAATTTTTTTAACGATTTTTTTTTCAGAAAATCAATAAATCTATTCAGCTTTTTTATAACTTTTACACAATTTTCCGTTTGAAAATGTCAAAAAAACCTCGTGTGTTTATGGCCACATTTTATTCAAAAAATTTTGAAAAAAGATTCCCTGCATTTTCCCTGTGGGACTCAAGAGAAGTGCGTGTGCCTTTAAGATTTCTATTGTTTTAAAAACTTAAAACAAAGATTTAAAAAATTCTGCTTTCTAAAAATACATAATTAGTTATTTTTTTGTGTATTTGTTTGGAAAAAATCAAATTTATCGATTTCTGTGAATTTTTTTGTGAAAAAAATCAGTATTTAGCGATTATTGTGCAATTTTTTCGGAAAAATCAATTATTATCGATTTGTATGAAAAAAATCAATACTTATCGATTCTTTGTGATTTTTTCGGAAAAAAATCAATAATAATCGAATTTTGTTAATTTTTTAATCAAAATTCGGCTTTTTCCGGTAAAAACATCTAAATTTCGCAAAATTAATCTGATTATATATTCTGCGAAAAATTTAAATTTCTCATACTTCGAAAAATCGAATATTGTAAAAATCAATAATTTCGATTTTTGGTTAATTTTTAAAAAATCAAGAGGTAATTAACGACTTTTTGATTTTTTTTTTGAAAAAAATCAATAATTATGGCGTCGTTTTTTTTTAATTGATTGGAAAAAATCAATAATTATCGAATCTCAAAAAACTTTTTGTAAAAATCAATAATAATCGTTTTTGTGTGATTTTTTTCGGAAAAAATTAAACATTATCGTTTTTTGAATTCTTTGAAAAAATTGATAATTATTGATTTTGAATTTTTTTTTGGAAAAAATGCAATAATCATCGATTTTTTTGTGAATTTGAAAAAAATCAATAATTATTGCCACGATTTTTCCGATTTTTTCCAAGAAACAAAATAAAACAATAAATTTTCCTTACGCCACGTGTCAATTACACCCCACGTGGCAAATCGTGTAGAGCGCGCATTTCGAATAGGGTGCCGCCGAAGAAGATTTCGCGTTCGATTTTTCGAGTTTCCTTGTCTTTCTGAAATTTTTTTTTTCTAAATTTTCTGAAAAATGTTCTGCTGTAAAACCTCTTTTTCCTCTCTTCTCCGCGCCATTTCGCATTGCTCTTTTTTTTATCCTTTTCCAGCGTTTTTATCTCTTTTTCAACTTCCCGCTCGTTGCGCATTTTGCGCGGTCCTGAAGAAGGTTTAAATTTTTAACAGGGGAAATTTGCTAGGAGAGTAAATATATTCGCTGTGAGACCCGTGGACATGAAAATTTTTATTTTCCGCTTAAAATAAAGACAACTGAATTTCGCTTATATTGTGATGTTGTAAGCTGAAAAAGCTGAATTTTGATAAATTGAAAAAAATTATCTTTAAAGGCGCATTTATTGATTTTTCCAAAAACAATTTACAAAAAAATTGATCATTCTTGATTTTTTCCAAAAAATTAACATAAATCGATAATTTTTTTTCCAAAAAATTCAGAAAAAGATTATGATTTTCAAAGTAAATACTGAACAATCGATAATTAATGATTTTTCAAAAAAAAAAAATCACAAAAGTCGATCATTACCGATTTTTTCCAACAAAATTTTCAAAAAAAACCACAATTATTGATTTTTTCCGAAAAAATTACAAAAAAATCGACAAGTACTGATTTTTTCTGAAAAAATTACTAAAAATTGATAATTATTGATATTTTACAAATAGTTAATTATTGATTTTTACAAAAAATTCACAAAAAAATCGATAATATTTTTTTCAAAAATAAAATTACAAAAAATCTCGGGGATCATTATTGATTTTTACCAAAAAAAATCACAAAAATCGATAAATCTATTATTGATTTTTTCCAAAAAAATTACGACGAAAATCGATAATTATTGATTTTCCCAGAAAAAATTCACTGAAAAATCAATTATTATTGATTTTTTCCGAAAATAAAAAAATTGATAATTTTTCAATTTAAAAAAAAATCACAAAAAATCGATAATTATTGATATCTAACAAGAAAATTACAGAAAATGGATAAGTATTTTTTTACGAAAAATTCAACAAAAAATCGATTTTTGATTTTTTTTCAAAAGAAAAATCACAAAAATCGATAATTATTGATTTTTTCAAAAAAAAATCACAAAAATCGATAATTATTGATTTTTAGGCGGAAAAGCCGAATTCAATTTTTCAAAAAAACAATCGATAGTTTTAAAGGCGCATGCGCCTGGATCTCACAGCGAAAAGTGTATCTTGCAAATTTTTTGGATAATTTCGCTGAAAAACGTATTTTTTAGACAGTTATCTCTTACAGGGAAAATTGTCTAAATCAAAAAAAAATTGTTTGTTAAGCAACATTTTTTCAGTTTTCATAAATTTCAGTTTTTTTTTCGCGAGAAAAAAAGCCAGCGAATTCTCGATTGAAAAATCAGAAAAAATATTTTGGTATCAAAATATTTTTGGTATTACGATATTTTGGGTCCCACCTCGAAAAGAGGATTTTTCAAATTTTTAAGATTTTCTTTGCAACTTTTAACAATTTTTTTTTCGGATATAAAAATCGATTTTCGCTGCGAGACCCAAATAAAATAGATTTTCTCGATTTGCGATGAACTTTTGAGTTTTGGTGAAATTAGATTCCAAAAAAATCGCAATAATAAATGTATCAAAAAATCAATACTTTCTGCGTCTCCTTCTCATCGTCAGTTAGTTTCCGCTTTTCGGGTCTCCCACGCCACGACATTTATGTCAGTATTCTCTTGTGAGCTGGAGCACAACGAGAATGAGCTAGTCGTCTGATTCTGACGGATCATTTCGTCAAGATTAGCCTTCCCTCCATATCCTGCCGTGGTTTTGCCGCAGCTGGAATTGCATCCTTATTCACTGCGTCGACGATGGAAAAGCTCGCTGGAGTACCTGGAATTTATCGATTTTTTATTGATTTTTTATCGGTTTTTCTCGATTTTTTTGATAACTGGGGGAAAACTCGGAAAAATCGATATAAATTTCGATAGGAAAATTCAAAAAACTTCGGGTCTCACAACGAAAATTGATTTTTTGGATTTTCAAATTTTTAAACTTTTGTTGTAACAACAGTGGAAATTTTTCGAAAAAAATTCAGTAATCGATTTTTTGGAAAAAAGGCAATAATTTTCGATTTGTTGAAAAAAAAAATCAATAATTATCGATTTTTTGTGATTGAAAAAAATCAATAATCTTCGTTTTGTGATTTTTTTTCGAAAAAATCAAACAATTATCGATTTTGGATTTTTTGAAAAAAATCAAGAATTATTTTTTTGTGAATTTTATGTAAAAAATCAATAGTTTGCTTCGTTTTTTTTTGGAAAAATCAGTAATTATCGATTTTTTGTGGATTTTGTGAAAAAAATCAATAATTATCGATTTTTTTTTGTATTTTTTGAAATGACAAAAATCAATAATTCTCGAGTTTTTGTGATTTTTTTTCGGAAAAATCAAAAATTATCGATTTCTTGTGTATTTTTTTTTGGAAAAATAAATAATTATACGAATTTTGTGATTTTTTGTAAAATATCAATAATTATTATCGATTTTTTGTGATTTTTTTCGGAAAAATCTTATCAATTTTTGTGATTTTCTTTGAAAAATCTATAAATATCGATTGTGGTGATTTTTTTTGGAGAAATCTATAATTATCGATTTTAGTGAACGAATTTTTTGTAAAATATCAATAGCCAATTATCGATTTTTTTGTAATTTTTTCGGAGGTAATCAATAATTTTCGATTTTTAATGATTTTTTTGGCCTTGGATTTTAAAAATTTTAAACTTTTAGAATAAATTTTTCCATAGTTTTTTGTTGAAAAAATCGTTTTCTGAAATTTTGAGATTCAATTAATTTTTTCTTTAAAAAAATCGTTGAAAAATTAATTTTTTGGAAAAAGAATCAGACGAAGATAGATTTCGCTGTGAGACCCAATTGGGCTCCGCAACTAGTGCCTGCGCCTTTAAATAGTGGTCGTGATTTTTTTTTTTGTTAAATTTTCCCGCGAAATTAAATCAGATTATTTCTGCGAAAAAGTGAAATTTCTCAAAGAAACTTTTGAAAAATCAATTTTTAAGACAACCCCTAATTTCTCCGATTTTCCTGCTAAATAAAAGCATCTAAAAAATTGGAAAATCCACAGAATTATCGCTGTGGGGCACAAAGTTCGGCATGCGCCTATAAGATTATCGATTTTTTTCAAATTTTTCAATCGAAATCAGGTTTTATTTTTCAGTAAAAATCATAATTTTACGAAATTAATCGGATTTTTTGTGCAAAAAATTCAAATCTTTTTTTACGTTTTTTCGCCAAAAAAACCATCTAAAAAATTCGAAATTAAAAGTCCCGAGCAGGTTATCTTCGCTGTGAGACCCAAGTCCGTGCTTTAAAAATATCGATTTTTTGTTAAATTTTGCAATCGATATTTGGCTTTTTTTCCGGTAATGAAAAAATCATAATTTTGCGAAATTAGTCTGATTTTGTGCGAAAATGCGCAATTTCTCATAAAACTTTTGAAAAATTGATTTTTTTTTTCTGGAAAAACCTATTTTTGTCGTTTTTTCGCTAAAAAACATCTAAAAATTCGAAAAATCTCCCAAGATAGTTTCGCTGTGAGACCCAAGGCTCCTGAAAGTCCCTGGGCCTTTAAAACTATCTTTTTAAATTTTTAATCGAAATTCGGCTTTTTCCGGTAAAAACATCACAAGTTCGCAAAATTAATCTAAGATTTTTTCTTCGAAAAATTCAGATTTATCATAAACCTTCGAAAAATAATCGATTATTCCGCTAAAAAATCATCTAAAAATCGAAAAATCCAGACAACGTTCGCTGCGAGACCCAACATGCGCCTTTAAAAATTTCGATTTCCTGTGAAAATTCTCACAATTTCTCCAAATTTCCCGCCGTCACATTCGTCGTTTCCAAATCATAATCCTTCATCATTGAACCATCCGAGAGGACTACAATCGTCCATCTGAAGTGGGAAAAGATCGATTTTTTGTAGAAAATCATATATTTAAATTGATTTTTTTTACAATAAAAAAAATTTTGGTACAGGATTTTTTTGGACAGTTCTGGTAAATCGTGAATCGTGTAATTTGGGCTAAATTCATTTTTTTCAAAAGGTCAGGGGGGGGGGGGCACTGAAGAAAAAATTTACAAAGCGTGGAGCGAAAAGGAGTAGATATACAGTCGCGAAGGAACGATCGCTCCGCCAAATTTGCACGCGGCAAAGGGGCGTGGTTTATTGGGGGCGGGATTCCGGCGCAACCCTGCGGCACGCTTTTTTCTCTCTTTTTTCGCTCGTTGGGTAATTTTCAGTTATTTTTATTCGTTTTCTGTTCGAAATTTCATTTCGCTCGATTTTGTTTTTTCGGATATAAAAAAGTGTCCAACCATTTTTTAAATGAAAAATAAACAAGTTTTCCTAACAGATTTTACCCGAAAAATGCTTTGTTGGTCTCTCTTTGTGAAATTACGTTTGTTAAGAGAGAAAATGGGGGAAAAAAAGTAAAATGTGAATTCAGAGGAAGCGTTTTTTTAACGTTTTGCTTCGTATATGGCATACAGAAGAGACAAACGAAGCCTTTTTTCTAGAAACTGATAAAACTTGGTTATTTTTTAAAAATAGACACTTTGTTATCCAAAAACGATTCACAAAGCGAAATCGTCAAATTTCGAACAGGAAAGAATAAAAACTGAAAATTGCCGCATGAAAAAAGCTAGAAAAAAGCGTGCGCAGGGTTGCGCCGGAATCCCGCCCGCAATAAACCACGCGCCTCCACGTTGCCGCATGCAAAATTGGCGGAGCGATCGTTCTGTCGCGACAGTATGTCACATGTAAGGTAACAAGGTTTGGTTTTCAGTTGAGAAAAGGGGGATTTTTTCTCCCGATTTTTCGCAGAGTCCACGCTCTCCTCATAGCCGAATACTAGAGCGCGCTTGCAGCGACTCTCGTTTCTGCAGCCGCGGTATTTTGATTTGCCACTAGAAAGCAGATATTTCATTTATCGAATTTTTAGGTTTAAAATTTTTTTTTTCTGTATTTTTCGAACACCTTTTGTCAAACAGTAAAAATCGAAATTAAAATAACTAAAATGAACTTTTATTGTCCACTGATTCTTGGTGAAATGGTTTGAATTTGAAGAAATTCTACCAACGGGCTCTCTCGTATTGTCTGGATATTGTTCTATTGAGATAAAATTTGGTTGTAATACATTGTTGAATTAAGGGTGAAAAAATGGTTTAAAACGATTTTTAATAGAAAAAAATTCAGAAAATACGAAAAATCTGATCATTCTAAATTCGAACCATTTCGCAACCAGTGGACGAAAAAAGTTGATTTATTTTAATTTCGATTTATACTGTTTAACAAAAGGTTTGTTCGAAAAAAACAGAAAAAAAAATTTAACAGCCAAAAATTCGCTAAAGCTAAAAAAGCTGCTCATTACATTGGAAAGGCAAAATACCGCGACGGATGCAGCAACAACGAGCGAGAAGCTGCAAGCGCGCTATTTCTATTAATTATTCAGGCTTTAAGGAGAGCGTGGTGCAGAGCCCCAATTTTAAACAAAAAATTGCGGGGTGAAAAAGTTAATATTTAAAAAAACGAGGATTAAATAAAAATTAAATAAGGTCAGCAATGTTCATTGGCATCTCATTTGTGTCGAGAAGTACTGCTCAATGTCGAATTCGTACGTCGTCCGTTTGTTTGACGAAATTGATGGCGACGCCCTTGCGGCCGAAACGTGCCCGACAGGCCGATACGCAGTATGGATGTAGAGCTCGCGGACTGTTGTTCGGCAAATCGTAGTATCTCCTGGCAAAGTTTTAAAAGCTGATTTTTGCGATTTTCGCCATTTTTTGACAAAAATTGGCGAAATTCGGAATTTTTAAACAGATTTTGACGTAAAGTAGAAAAGGTTCCAATGCCAAATTGTACGGTTAATAGCCTGAAATACTTTAAATTTCCTTTTTTGCACAATTTTAACAATGAAACCCTGTACTTTTCGCTACTTTTAGAAAAAAGCTTCCAAAACGATTAAAATTGCGGCAAATTTTATCTGAAGATTTTCGCAAAGTTTTCACCTACAAATTGAAGAAATCGGTATTTTTAAACAAATTTTGGCATAAATAGGTTAAAATACCAAAATTTTACGGTTTTTAGCAATTTTTGAGTGAATTTTCAAAATGTTCCAGTATTTTTGCAACTATTTGGTTCTTTTCATCTATGTTCTTTGAAAATTCTTTTTTTAAGGTGAATTATGTTAGAAAGGGGTCGATTTTGCAGAATTTTGACAGATTTCGCATGAAAATTTGAATTTTAGGCAGGCGAAAATCATCAAAAATATAAGATTTTTTGCGACTTTTAGTTGAAAAAATTGTACAAAACGAGTAAAATTGACAAATTTTTAACGATTTTCGCCAGTTTTTCACCTAAAATTTAATTTTTTTTGTCTAGTGAAAGTTAAATTCAGTGTTAAAATGTATCTATTTTCGCTCAACCTGAAATTTGAAAATTTTCAATTTTTCACTAAAATCCACTTTGAGAAACCAGTGAAAAAATTTTTTCAATTTGATGAAAAAATTTGCAGTGAATTTTATTTTCTCTGCTAATTTTTCGTTGAAAAATGCACTTTTTCAAGTAAGAATTAGCGGGATTTTTGGATTTTCATCTTAGGTCAATTTTCAATAATGTTGCTCGCTGAAATTGATTTTTTCTCAATTCATATTTTGTATGAAAAATTCCACCTTTTTGCAGAATTTTGACTAAGAAATTGCCACTCGCCAAAAAGTCTGAATTTTCTATTTTTCTGTGCTGACAATCATCAAATACGATTTTCAACAGAAATGAAATTTTCGTTATCTTTCGCGGAAAATCATTGATTACCTGATTTTTTCGCTACTTTTAATTGAAAATAGTTTACAAAACGAGTGAAATTGGCAAATTTTATCGATTATCGCAAGTTTATAACCTAAAATTTAGCTTTTTTCTAGTAAAGTAGGGAAATACAGTGAGATTTTTTAATTTTTCACTGAAATACATGAGAAATTAGTGAAAAAAACATATATTTGGCCAACTTTTCATATTTGATATGAAAAATGCCGTTCTGAACAAAAAAAGTGTCTGGAACCATTCAACTTATTATCAATTTTCAGCTGAAAAATTCATTTTTTTTTCTCAAGAATTCGCATTAAAACTGCGGAATTTCTTGTATTTTCAGAAAATGATGATGACACGCTATTCTTCGCGGAAAATCATTGAAAACCTGATTTTTTCGCTACTCATAGTTTAAATCAGCATGGTATTACATATGAAATTGGCAAATTTTATCAATAGATTTAAGTTTTTAACCTAAAATTTGGTTTTTTTTTCAAAGCGAATAGGGAAATCTTCAGTGTCAAAATTTACTGATTGGGTAAATGGAAATTGTGAATTTCCATTGTAAAAATTTCTGCTGGATTCATTTTTCCCTAATTTTTCATATAATTAGGCTAAAAAATGCAATTTTTCACAGGTTCGCATTAAAACACCGTTTTTTGTAGTTCTTATCAACGAAAAATGCTATTTTTTGCGGAAAATCACTGCAACTTTTTCTGCAGTCTCTCGCGGGCCAAGGAAAAGTGGTTTCTAGGCCTTGGCCGAGGGGCCGACAAGTTTCAGCGGCCATTCATCTTGCTTTGTTGTTTTCGCCTGTTTTCTTTGTTTTTCACAGCTTTCTCCCGTTTTTTCTCATTAAAACTGATAAATAAATGCACTATTTTTTGCAGATGCTAAAACAAGTTCCAAGTAAAAAAAATTATGTATGTCAGTCGGCAAGCAGCGGTGAAAATGGGCAATGTAAAATGATGGATTACGGGAGATACAAAACCTGAAATTTTTCTTAAACATGATACATATGCTGCTTAGATGCTGATACTGATTTTCATAACGAGACCGCTGAAAGTTTTGAGGTTTCCACAATTCAACTTTTTTGGTGATTATAAATCGAGATTTTCGCACAAAAGGTTGAATTGGTCTGAAAACCTCAAATCTTTTTCAGCGGTCTTGATATGAAAACCAGGTAATTTCAGCCTGGAAGCATCATATGTATCATGTTTCAGAAATTAGGTTGTGTATTCCGGTAATCCACCAATCATATTGCATTGACCACTTTCACCGCTGCTTGCCGCCTGAATACATAATTTTTTTACTTGGATTGTTTTAGCATCAAAAAATAGTTAATCAGTTTTACAGTAAGAAAAAACGGCAAAAAGCTGTGAAAAACCAAAGACTAAACACGGAAAACAACGCAAAAATGGCCACTGAAACTTGTCCCATCGGCCATCTCATGGCAACCACTAGCTTTCTCCCTTGTGAGGATAAAAATTTGCAGTAGGAAAATGCTATTTTTCGCGGAACATCGAAAATGCCTACCAAGGACACTTGCGGAACATCAAGTCATCTCGCTCAAACATCAGTAGAAATGAGCAGCTGACACGAGTGGTTCCTGCTCTAAACTCCTTCATAACCTCATCACGATCCTTCTGCTCCATATCTCCATGCTTCGATGAGACTTGGTAAAGTCTGCTGGGCTCCGTCATCTTATCAGTCAACCAGTCCACCTTTCTACGTGTATTACATAACAACACGGACCGCCTGAGTGATGGTTAAGGTGTCGTAGAGATCGATAAGCGTGTCGAACTTCCACTCCGATCAACTGCTACGAAGACAACTGCTTGATGCCTTCCAGTGTCAACTCGTCACGCTTCACAAGGATCCGAATCGGATCCGTCATGAATTCTCATCATCTCCAGAATCTCATGAGGAAGCGTCGCGGAAAGCAGCACCACCAGGGCTCCAGGCGGTAGATAGCGATAGTTATCGGAAATGCTCCTTGAACCCCTTGTTCATCGTCGGCTTCATCGAGCACGAGATGCTTGATGGCGCGGGTGCGCAGGTTTCGACGGCGAATCATATCGAAGACGCGTCCCGGAGTAGCCCACGTGCTGGTCGTTCCAATCGAGCTTTCGGATGTCCTCGCCAAGACATTGGTGCCTCCGAAACAGGCCTGGCACTGGACATTCGTCGCCGAGCGCCAGCACTTTTTGGAGTTTCGAGAACTGCCAGCTCCGTGTCGGCGAAACAGAGCTTGGGTCTCGCGGACGGGTGTCTAGCGATTGGAGAACGGAGATCGAGAATGTCGCTTTTTCCTGTTCCGGATTGAGCTTGAGCGATGACGTCACGAGCCTTGAGAATTGCGGGGATTGCGCGTTCTGGATGGCAGATGGATTTTCGAAGCCGTACGCGTAGATTCCACGAAGCAAGTCTTCTGCTGGAAATCGAAAAAAATTTTGAAGTTAGTTCTATATTTAAAGCCTGTGGTGTAGTCGAATTATTTATTTCTTTATTAGACTCAAAATTGCCTGAAAAAAAAGTGTACAAAACGAGTAAAATTGGCGACTTTTATCAATTTTCGCCATTTTCTAAAAAAATCGACGAAATTCGGATTTTCAAACAAATTTTGACGTATAGTAGGTTAAAATTCGATTCCAAAAACGGTTTTTAACAATTTGGTCGTTCTTAAAGTGTAGTCGAGCAATTATTTTTTTCTTTATTAGACCCAAAATTGTCTGAACACACCGAATTTCAGAATGTAACTTCTTGAAAACTCAAAACTTTTCAAAAAAAAGTTAAGATTAGCCTCTTGAAAAAAGCCCTAAAATTTAGTGAAAATTTGAAATTTGACCAACTTGTCTCCTGTCAAGCGGCTGGAAACAGTTTTCTTTGAAATTGTCGTATAATTTTGGGTATACAGCTCGATTACCTTGCGTCTTCAGCTTAATTTAGGTATTTAAAAGTCGATGGACGAAGAGATTTGTCAAATTTTTTTCACCAACTATCTTCGTCCATCGACTTTTAATACCTTAATAAAGCTCGGAAAACGCAAGGATACGTATACCCAAAATTAGACGACAAATTCAAAACAAATTGTACATTTCCAGCCGCTTGTCAGACAATTTGGTCAAATTTCAAATTTTCACTAATTATAGGCTATTAGCCGCCATAACTTTTATTTGAAAATTTTTCAAGAAGTTACTCATTATGAAATTGAGCGGTGTTTTCAGACAATTTTGAGTCTAAAAACGCAATAAAAAAAATTCAACTACCAACGGTGGAGCGAAAATTTATTAAAAACCGTATAAATTCTGGAATCCTACTTTACGAAAATTTGTTTAAAATTCCGAATTTCAATATTTTAGATGAAAAAATGGCCAAAATCGATAAAATTTGCCAATTTTATTCGTTTTGTACACTTTTTTCAACTAAACTCAAGTAGCGAAAAATCATGTTACCATTTGATGATTTTCAGCTGAAAATTCCAATTTCAGGCAAAATTCTTGTCGGTACAAAAAGGGTAATTTTTCAGAGAAAATATGGAAAGAACTGATAAAAAAAACTGTTTTCAGCAAGAAAAATGTTTGAACAAATTTACCTGTTAAATCTGCTTAAAAACCGTAAAATTTTGGAACGTTTATAACCTACTTTACATCAAAATTTGTTTAAAATTCCGAATTCCGTCGATTTTTAGATGGAAAAATGGCGGAAATCGATAAAAGTCGATCGCCAATTTTACTCGCGTGGTTTTGTACACTTTTTTCAAAGTAGCAAAAAAATAATGTTTTGACGCGAAAATTTGTTTTCAGCGACAAAATTCGCTGCAGAAAAAGTTCATTAATATGAAGCTTTCTGCTTAGTTATAGAGAAATTTGTTAAAATCGATAATTCAATACCTCAAGCACCACTTTGTCAAAAGTTGGGATAATTGAGACCTCGTCAGACGACCTTCGAACTCCACAGCTCGCCAAATCGTCGTTTTTCTTCTTATTTTCCGCCATTTTTGAAGGAAGAAGTCTGTAAAATCGATAAAAGGAATATTTTCGAGCATTTTCCGTGCAGAGTAATTCAGCATTTTTTGGAAATTATCAAAATCAATGTATTACAAAAAAATCAAGAAAAACGAGGAAAAACGATAAAATTGATTCGGGCATTTTGCAGATCAAGATTTTTAGAAGGAAATTAACATAATAATTTACATCGAAAAAATTAAGAACCTGTAAAATCCATAAAAAACTAGTAAAAGCAAGATTTCGAATGTTTTCGAAAATACCCTGTTTGTCGAGCATTTTTGCAGAGAATTTCAGCATTTTCAGGTGGAAATTTACACAATAAACGAAGTTACATCGAAAAAATCAACAAAAATGGTGATTTATCGGCTATTTTCGCTCATAATTCGTAGGATTCGATTCGAAACTAAAAACTTTCGAAATTCGAAAAAAATAGCCCTGGCCTAGCGTTCCCCTCCTAGTCCACGGCCGCGCCGATTTACGGAGAGTACGATTATTGATCGATGACGCATGGTTTCCGACTGTTTTTACTATTAAATTACCCTTAAATCACAATTTTCCATAGAAAACGGGTGGAATTCTCTCGAAAAATGAGAAATCACCAAAATCGGCGCCGGTTTCCGATCAGGATAATGCGATTTTGGTTTGTTTCATGAGGTTTTTTTAACATCGAAATGATTATTTTTTTGGTAATTCCAGGCGCTCAAAACACAACGGGACAAAATGAAGAAAATGATCAAGCGAAAAGAGAATTGTTTGGAGAAGGAACCACAATTGGCAAAGCAGCTAAGGATGGCCGGAAAGAGTAAGAAATTTCAGATAATTCAGTTTTTTATATTAAAAAAAAAAAATAGATTAAAATTTCGCTTTAGCTAATTCCAGCCGTGCTTTACTCCCGCTTCAAGCAACGCCACCAAGAGAAGATTACATGAGCCGATCAAACCTTGAACCCTGCACCTTAGCAAGCTATAATCGAGCTAATGGTATTGAAAAATCAGAAAAAATTGAAGTGTAAATTTTCCAGCAAACAAATCAATAAATTTCCTGGTAAATGAACCTATTCGCAGAAGTGCAACAGCAAGTAACCGATGGCCTTCGAGAAATGAAGCGCTGAAAAAGATTAATCAGAACTTCGAGATCAAATCGACAGGATTATGGAAGAAAAAGAGGCGGCGGAATATCAGGAAGAGATCGAAAATGCTGTCCGGCCAGCTTTCCAACACGGATCTCGGGTAACGTTGAGAATGGAGGATCTGTTGGCGGGCGGAATGGGGCACAGTTTCAACTTCCAGAGGCTCCGAGCCATGAGCCGCCTGAAGCAGAGCGGGAATGGCAAAAAGGTTGTAGATTTGCCCGACGAAAATTCCTAAATTTTCCCTAAATAAATAATTTTGTTTTCAGATAAAGAGAACGTCGCGAGAAGATTGCTCTGGAAGCCTAAATATTGCTTGTTACTGTGAATAAAATAAATTCATTATATTGTTATATTTTCTATACAATCTGGTCTTACTGGCGTTGTTCTGCACGTAAAATTCGTTTAAATAACGCTGTAACAAAAAATCTCAGTTTGCGCGTAAAATTGAAAATGCCAGTGACGCAATCACCACGACGAAAAATCCCACAGTTTTGGAAAATTGCGGTTTTTCAAACTTTTTTTCGCGTTTTTTCGGATGCTATTCAAGCGGCTATAGACTGTTCAAATAAGAACGGTCAGAAAATGAGAGACGTAGACAAATAAAGAGATATTGACTTTTTAGGCTATTCTGTGATAGTAACAAACCAACAAAGTTTGTGTTCCCAGTCTTTTCTTTGCAAATTCTCAAGAGTTCTTCTTTGCAGATGCGTCGACGTGAAGCTCTGGACAATTACGAGCATGATGGTAAGTTAAAAAATTGGAAAAAAAAACTTCGGTTTAAATTTTATTATACTTATTCCCTTTTTTTAATTAAAGGCGTCTATGACGGCTCATTCATCATTCACGACGTAGTTGACGCATTCCTCCTTGCCCGAAGGGCCTAGTGGGTTAACGCGCCATCACTCAGAAGACCACAAGTTCAAACCCAACGAGGCTCCCCCGCTTTTCTACCCCTAGCTTGAGCAATCAAATCCGAACGCGTCGGAGCTGTCTCGGAGACAGAAGCCTCATCAAATATATTGATTGCTTCCAAACCTATCGCACGTTTGCGCTCCTCATTTCCGTAATGGCGTTGCATGCGTAAGCTTGATCTTTCCAGTTTTCTACTAAGGTGAGTCATTAGAGCAATGGAGTGAGCAACTCGTTCCGATAATTCGTATCTCATGAGCAAATGCTATGCGGGACGCGGGGCTTTATGGAAAGAAATTAAACAAATATTATTCGTTTTCCACATGTGTGGCTCAATTTACTTCTTCTTTTTTTACCTCATTTTATAAAATTGTCAGCCCTTTTTCTCATTCATTTGATTTTCTGTGGCTCTTTCAGCTCTATGTAGTTCAGTTTTTCATCTATTTGTTTTAACGTGGAGCAAAATATGGTTGAAATTTGTCTGGTAGATACGGTAGCTTTAAAGGCGCATACTAAATTTAACAGTGACAAAATTAAATATTTAGTTCCATATGGAATTTCAATTTGCCAGGCTGTCCCATTACGGTTTGATCTACAAAAAATGCGGGTTTTTTTTAGGCCAATAATGTGACGTCAGTCCGTTCTTAAATGCGAAATCAGATGTGAACTCTGGGTCTCAACTCCCGCATTTTTTGTATACGTAGATCAGACCCAAAATGGAACTCTGACACCAGGTGTTCGCCGCGGAACCAGTTTTATACCGAATTTCGTATGCGCCTTTCATTCTACCGTACCCGGTTCTGGAAGTTTGGGTAAGTTTGAAAAACGAACTTTAAAATAGAGTTTATTAATTTTTGTTGACATATTACTTTGTGCAATACCTCAAAAAATATTATAATCCAGATAAACATGGTTTTTTAAAACGTTTTGCACAAAAAGCGATGATTTCGCTTCGAAGCCACTTTTATAAAACGCCTTGTGCGCCTTTAATTCCACCGTACTCGCCAAAATTGAATGAGCGAGTGAACTATTTTAGCGAAAAAATCGTTCTGATCGGTCCTGCTCTTCCTCTATCGGCTCTGGCAACGTCTTCCTCTTTGAATCTGCTCCATTGACAATCGCCTACCGGACTGGTTCTGGAAAGCCGTCCACACGGACAAGTACATTTTTACAACTAAAATCGAGTCGCGACGCGACACGCAACGCGCCGTAAATCTACACCAGATATGACCGAGAAATGCGGCCTAGTTCGGCCAATTCTTCCATTTTAAATTATGAAGCCAGAAATTCGTGTATTTTTACAAACTGAATGTGAAAAAGAAGCTAAAATTTCAATGAAATAGAGATTTTTCCCGTAATCTCACAGTTTCGCAAAATACTATGGTCCCATTAAAAAACGCTGAAACCTAAATTAGCGCGTAAAATTCAATGTATAGCGAACATCTCTCACGTATTTCTGGCTTTTATAACTCCCCTCAGATATTGCGATAGAAGCGGTTGCCGAACTAGGCCATATCTGGGGTAGATTGACGGCCGCGTTGCGGTAGCGTCACGGCTCGATTTTAGTTGTGAAACTAAATGCATTTTCCTGTGGAGTACACGCGATGTCCGGCGGGCGCTTGTCAATGGAGCGCGAAAAATTCAATATGGAAGGCCAGCACCCCGTGTTAACATTAAAATTACAAGATTTGCCCCCCCAAACATCCCTGGAGAACCTAGAAAAACCTGGTGTGCTTGCCTGACAACAGCGTTCACCGATAAAAGGGTGACGGGGAGGGCTGCAACAGAGCTTTTTTCCTCGTATAGCAACTCTTTGAGAACTGACAGCACTTTTCATATAACTCATCACTAATCGCTGCTCGTGGCGGTTTTATTTTCTAGTTCCCCATTTAGGGCTAATGAGTCAATTTTGTCTGTTGCTCAGAACTCTCAATTACCGATGCTATTAGCAGAAGTACTTAGCGCCAGAACCAGAGCAAAATCATTTTTATTTAAAAAATGAGTGATGTTTTCTTCAGTCTCTGTTTTTCAGGTTTTTCTCGTTATTAGGCGGTAACTTTCCACATACACTTGGTGTCAGAGAGTCCCATGGTTTGATCTACAATAAAAGTGTGACGTCAGCCCGATCTTAACCTTGTGAGTTGAAAAAAACATCTGCGTCTCGTTTCCCGCATTTTTGTCCGAGATCACACCGTGATGGGACTCTCTAACACCACGTACACATCTACCGAAAATTTCGCTGAGAACAAATTTTTGCGCGTCAAACCTGATGTTTCCGCCGTATATCAATACATTGAATTTGACGCGCAAACTCAGTTTTCATGGAGAATTGTTGAAAAAATTGTTTAATTTCCGGAAAATTAACATTTTTCAGAGAAAATCAAAATTATTCTGTTTTTCCATAAATTTCTAAGAATTGTGGCAGATCTCAGTTTGTTCTACGACAAAATTCGAATTTCCACTGAAAAAAGTGAAAAAAGAAGACGCTGTGTAAGCCTAAAAGCCTAAGACTAGGTGTAAGCCTAAGCCTGAGCCTATCCCTCAGGAGAATAAGCTTGAGCCTAATCGTGAGCCTAAGTCTAAACCTAAGCCTAACAAGCCTAAGCCTGATCCCAAGCCCGCATGGTGCCAGGCTGACCCATAACGGTTTGATCTACAAAATATGCGTAAAGCGAAATTTTTTGCCCAAAAAGTTTGACGTCAGCGCTTTCTCATGCGATATCAGTTGAGAACTCACTGCGTCCCTTGTCCCGCATTTTATGTAGGTCTACGTAGATCAAGCCTAAATGGGACGACACCACGGGAAGATCCCGAAGTATTCAATTTCCAAAAAATCAATAAAAATGCAAATAACATAGATATTCCCGCCTAGTCCAATAAATTATTTTTTTTTTGAAACTTCAACCTTTTCATGTTAAACTCGTTTTGTGGGAATGCATAGTCCCAAAAGCCATATTTGACACGCAATTTTCTTTGATAGACTTTTTTTTGAATTGATATGTCATGAGCATCACTCAGGTGGTTCCCAAATGGCGTCTAGTACTTGAGCCCTAGCCACCACCGTCTCGAGCGGCCGAAACCCAAAAACAAATAAAAATGAACAGTTCTCTCTGTTTCAAAATCTATATGTTCCTGTTCTTTCTAGTATCTTCCCTCTTCAGCCCTCTACTGCTGCTCCAATTCTGTTCCATGTTATTTACCGTACCGAACGATTTAGACGAATAACAGGACCCCCTTTTCCCGTTCAGCCGATGAGCCAATGTGTTGTTGGCTAATTCTGGGTGTTTAGCTCATTTGGAGGAACACTAACTTCCCTCTCTAACTACACACTACATGGAAGAGTGTTTTCAGATTTCTAGGCCTCGCAACTTTCCTTGGTGGCCAAGAAAAACTAAAACTTCAAGGTCAAAACGTTCATTTTTGTTGAAAACTACGAAAATCGGTTTTTACTTGATTTTTTGTAAGCGGAAGATTTCCTAAATTTCTAGGCCATGTGCTTTTTCCTGCTTCTCTGAAAATTTTGTTCAAATTTTCTTTTTTCAAAATATTCCCCGAAAATCTTGTACAAAAAGAAATTTTTGAGCATTCAGATCATTTTTTTAGAATGGAAGAGTTATCCAGATTTCTAGGCCACTGTATGGCTTTTCGTGGTGGCCTAGAAAATTTTCTTGGAAATCAGGTTTTGACTTGAATTTTCGTAAGTGTAAGAGTTTTTTACATTTCTAGGTGATTTTTTCCTGATGGTAGGAAACTTGTTTTCGTTTAATTTTCCCCTATTTTGGATATTGAATACTTGTTTATTGGTGGAAGAGTTTTCAGAAATTCTAGGCCACGTGGTTATTTTTGTAAAAGAAGATGATATTTATAACATTAACATGTGGTGACTTTTATCAGATTTTTTGCCCAAATACCATTTTTACAAGGTAATTTTTTGTTATATGATCTTTGTGGATAGAGTTTTTAAAATTTCTGTTAGGCGAACCCTAGATGCACGTGGTGTCAGAGTGCACTTCGGTTTGATCGACGTGAATCTACAGCAAAAATGCGGGAGAGGAGACGCAGAGTTCTCACCTGATTTTACATGGTTAAAAACGTGATGACGTCACATTTTTTGGGGGCAAAAAATGCCGGCATTTTGTAGACATCAAACCGAAATGGGACAGCCTGACACTACGTGTTCGTGCAGATGGCCTATAAATGCTAAAATCTGTTTTTTAAATGTAACTTTCAAAGTAAAAGAAACAATTAGAAACAAGTTGGCTCTCGCCCACAACGAAAAGTCTGTTCTAGCTATGGGTCGCGAAAAGACTCGGCTACCAATTTTTTTCGGCTCCAGATCAATGACGCTGGCAGACAGGGACTTATCAGCTTGTTTCCGATTTACACACACATACACGTACACTTTCTCCGTATAACTTCTGATAGCTTGAAACGAGATTAATCATCATTCCAGCTATTCTGTTTTATTTATTAGGTTAATGCCACTACTACTAGTATTTTTTCATATTAAAAATACAATGAACTATTTAGACATAGATTCAAATGAGATGCCAGTGAGTTCGCACTGGTGTAAGTGTTTTGAATTAATAAATTTTTCAAAAATATCTCAGTAAATTTCTGAGAAATTTTGATTTGAATTCCCGCCAAGCATTTTTTTGAAAATTTTGAATTTCAGCCCATTTTGCCTTTTTTCCTTCAGAAAAGGTGAAAAAATTCAAAATTTGAATTCCCGCTACAAGATTTTTTTTGAAAAATTTTCGAACTCGCGCTAAAGTATTTTCTAATAGCCGAAGGATTAGTAATTGGAATCCCCGCCAAAACATAATTCAGAAAATTTAAATTTCCGCCGAAACTTTTTCTGATAAAATTTAAATTCCCGCCCATTTTGTCCAAAATTGCAAGAACATATTTTCAGTGAGAAAATTTGAAAATATTTTTTTCAGAAAGTTTGAATTCTGTAGCACCAAAACATTTTCTAAGAAAATTTGAATTCCCGGCAAAACTTTTTCTGATAATTTTTGGAAATTCCCCGCAAAAATTGAGGATAGTAAATGAAGATGATTTGAGCAAAGTTATGACGTGGCCGCGGAAAAAATTGATGGCCCAGTTTTCTCTTTTCGCGGCCACGTAGCCAGAACAGACTTTTGGAACCGTACAACCAACAAATATTTCTTCATGTCCCTTTCAAAAATACATAAAAGCCAGATTTTGACATTTCTAGGCCATCTAGACGTAGACGTGTAGGCCTCGAGGCCTAGAAATTTGAAAAACTCTTCCAGAAAATTTGTTCAGTACTTGAAAGCGCTCCAACAAATCTATGCTCAAATTGTAAAAACGTTTTATCAAAATATTTATTGAATAAATTCTTTTGTCGCACAAAGAGGTATCAGACCACCAGATTCGACCTTTGATCATTGTTTCAGTTGATAGGTATGGCAGGCGTGGTTGCGCCTCAAACCTGCCGGCCTCAAGCTGGGCAAGAGGCAGCCTAATGTCAGGGGCAATGCCCACATCCAAGCCCTACTTCTAAGATTATCTCGAAATTTAGCGAGTTTTTATTTGTCCAAAAAAAATCGGAACAGGTTAACAGACAAACATGAAAAAGCCGCCAAAACAGAACTTTCATAATAATCTGTCGGTAGTTTGTGGCCGTTTCTTGCGTCTCAGGCTTAATCCCTACTGTAATTATGCTGAGATTTTCTAAGGATCTATGATCCTTTCACTTTTTGAAAATTTTTGGCAATTCTTTTTAAGTTTGTTGAGATTAACTTATGACAAACAGTAACTAAAAAGCGTGTGCTGCCGCCAGATTTTCTAGGCCATCAGTAATATCAGTTGCGTCCTTGACCATACTGGACCGAGACAACAAATATTCTAGGACTTGAGATTGCGTTCCTCGTCCATTCCTAGTCCCAAAAATTCCAAGCTAGTTTGGCCGAGAAATAATCTAGGCCATCGATGTTAATGACGCCATTTCATACCCGAATTCGCCAGCCTAAAATTCTTAGGTCATCAGTGACGTCACAGCTCTTCCAAGCCTTGGAATGAGCATTTCTAGGCCCTCTAATCTAGGCTTGCAAATTTCCTAGGCCAGGTGACGCCATCCCTCTTCCGTGCTGGACCGGTCAAATGACGTCACTTCTCGTCCACCTACGTCGCACTTTGATTACCTAGGCCACCATGTAACGTCACTTCTCTTCCATCTAGGTTTCCCATGCCCTTCTCCTCTCACGTTTGGTATCAGTGTGTCATTTTGGCCTTGAATACTCTAACGACAAATGAAATGCGGGAGAAGAGACGCAGAATTCTCACTGATTTCGCTTTTCCGGGTTACGCGGTAGACGTGCTGCCGTCACATGTTTTTGGGCAAAATTCCCGCATATATTTTGTAGATCATACCTTAATGGGGTGTCCTCTTGTTAAATATCGAAATTTCACTCAAAAATTTTGAACGTTGACGTTTTGTCTCTGGTCAATTGGTCAGCCGCGCAGTGTTCCGGTGTTTGTGCTCATGTTTTCCATTTGTGCTGCTGCTAAGGCTTATTTGTTCCGGGCGGGGACAGGGGGGAGAAGAGGCGCAAAAATGTGTCATTATGTATATTTTGCCATTGATATTGTCCTTCTGCTCAGAGGATTTCCTCATTTTACGCCGTATGTGCAAAAGCATAATCACCACAATAATTTTGAATATAAGTTTGCAAACGCGCCCTATTGACCTCGCCCGTGTAGTCTGCGTGCACGTGGTGTCAAAGTGTCCCATATTGGTTTGATCTCGAGAAATGCGGGAGAAGAGCTGCAGACTTTTCAACAGTTTGATTTTGCATGGTTAAGAGTGTGCTGGCCGTCGGTCACGTTTTTCTGGGGGCAACAAGAAATTCCCGCATTTTTTGTAGATCAAATTGCAAAGCGGCCTATTGTTAATCTTAGCCCGTCTTTTGATTTTCTATTATTCTTCGGCACCTAAACTGTAACTACGACACTAAGTTACACTGTTAAATTCCGCCCACTTAATGGCACCTTTGTTGCAGAAATGTACCCACGACAACGAGCAGACACGACCACATAATTGAGACGAGAATTCGGCGGAACCGGCTGGCGCAGGTCGCCGCCACAATTGCTGCCTTAGCGTGATATGACTCTTGTTGGCAGGTAAGTAAAAAACTACGACACTCCGAGACCAAGAAGAAAATCGATAATCGAAATATTGAAAATTGCAAAATTTATTTCGCCGGATCATTTTCCATATCGATTTTCTGAATGGTATGGTGATAGCAATCCTAATCGTAGGGCGTCCCATCCCTGGTGAACCACGGACTCTTGACCTGAAAAATAGGTTTCGTTCGGTGGAGCACATTCGCATACACTGACATTTTCGGGTGGCGACACGCTTTACACTTGCAACATGCAGTACCATATGCCAGTGGACATTGAACGCCGACACGCATCTCTCAAAAGTTAGATCGGAAATTTCGTGGCATTTTGGTGATTGGCCGCCCGGTGACAGTCCGCGCAACGGAGCGCGTGACCGTACGGCCCGGGCATTGGATAACACGGAGTCATGCCAATGACTGTCTGGAATTTTGGAGAAATTTATTGATTTTTTGACGGAATTTAATGAAATAAGGAAAAATCAATAATCGACATATTTATTTCGTAAAAAAAAACATTCTTTTCACGGATTTCTTCTTCAAATTGCAATTGAAGAGTTTGCCAAACTAGGGAGCCATTTTGGTAACGCTCGGCCATATCTGGGGTAGATTTACGGTGCGTGTCGCGTCGCCGGTTTTGTAGTAACACTAGCAAAATGTATTTGTCCGTGGAATTCTGGCTACCCTCATAAATCGAAATGGCAGAGTTTGCAGAACTAGGCCATTTTGGGTCGGAGTGATTTTGTGTAACGGCGCGTCGCGTGTCGCGGCATCGCCGCTCGTTTTCAATTTTAAAACTATTTGTCCGTGTGGCGCACACAACACTTTTCCACGCGCTGTCCGGCAGGCAATTAGTGTTGGGCGCAAAAATAATTAGGAAGGCCAGAACCCCGTGTCCGTGTGGAGTGCACGACTTTCCCGCGCGTTGTCCGGCGGGCGATTGGCAATGGAGCGCGAAATAATCAATGAGGAGCTTTTTGCAAAAACAAATTACATAGGCTTCTTGGCCTTCCTTATTGCATCTTTCGCGCTCCATTGACAATCGCCTTAAAGCAGGGGAGTGTGTGTGTTTGTACCTTCTCCACACGGACAACTTAAAATGAAAACCGAGCCGCGACGAGACACGCAGCAACGCGCCGTCAATCGACTCCGGCCGTGGCCGAGTCAATATGCCTTACGGCAAATTCTTACATTTCAAAATATGAGGGAAGCCAGAAACGTGCGGCACATGTTATAAAATTAATGTTGAAAAAAAACTATTAACCCATATTTCGCAAAATAAATTATCGCTTTTTGTAAGAAGGATCTTTCGTGATTGAATAGGGAAAAATTTATCGAATTTTAGCGAATCAGAAAATATCCATTTTCACTAAGAATTTATCTAATTTTTCGATTTCTATTCGCTAAAATTATCGATTATTGCAATACCTGACAAACCGAGCATTTCAGTCATGAAATAAGATACATCTCGTCTTGAAGTTTGATCACTTTTCCCTGCAAAGAAATTTCAATTGAATGTATTTCGAAAAATGTGCTCACAGTTTGAGCTGCTTGACGAGTCAGCAGGTTGTTGTGCAGCCTTTCCAATGGATATTATATGGAAGAACAATCTTATGGACGTTTATTGTTCATCGGGTCGAGAAAAACATTTTTCGAATTTTCGAGATTAATTTACCTAAAATCTAAAAAGGAGAAAATTGAAGAGAAACGTGGGAAAACGTATTGATTTTTCAAAATTTTGTTGATTTTCTAATCACGGGGTTCTGGTCTTCCGAACTCATTAGTTGATCTTGTCGCGCTCCATTGACAATCGGATCTCTTTCCGGACAACACGTGGGAAAGTGGTGCACTCCAGAATACACGGTTAGATAAATACAAGTTTTACAATTAAAATCGAGCCGCGACGCGACACGCAACGCGCCGTTACCCCAGAGGCCGAGCCATAATGGCCTAATCAGTTCGGCAAACTCTACCATGGGAAGCCATAAATTCGTGTATAATCAGAGAACTTGCGCAATTTAACAAAATCGGTAGTAGTAATTTATCGATTTTCCTTCAATCGTCTCGATTTTTTAAAAGCCTTATCGATTTTTATCACTAATTTATTATTTGAATAATCAACGTTTATTGATTTTTGAATCTACATCATGATTTGTCGATTTTCTCAAGTACCTATCGATTTTTGCTGTCGATGCACCATGTGGAAACTTCGGCACGTTTTTTCGCGGCGAGACCCAAATTTTTTGAATTTTCAGTTCTTGGTCTGGTATACGGTAGCTTCTACCTCTACCGTCGATATGTGACAGATGCAAATAAACGGTATAATGATGATATTTGCGAAAACTCGTTCGTCAAGTCAATGACTCGCCGGAGACCACGTGGAAAGCGAAATTCGTTTGGTGTCAAATATCCTTACGGATTCAAATAAACTTGAGAGGCAATCAGACGGCGGTCGAGGAATACGTGGAACAAACTCGAAAATTCAATTTCGAGTCAACGTGATGCGATGAAGCGGTTAGAGTGTTAACTCAAATTTGAGCGGTAAACAACGATGCTCCGCACTCTCGCCGCAAGTTATGTAGTTTAACGCGTAAGCTGTGATGCATACGATAGTCCTGGAATGATATTTGTTAGCTCTCGCAAATGAAGGAATTACCAAATTTCGAGAAAAATCTATATTGATTAGCCTTTTAAAAATTATCGATTTTTTAAACAAAACTTCTGAATAATTCGACGGATTTTTCCAGAAGTTTAAAAAAGTTTTGGGTACAATTTTAAAAAGACAGCAAAGCTAATGTACGTAGAACACCAGGAAAGAATTCTGCGCTAATATCGGATGCTTCGTAAACTCCACGGGCTTGCGGCATTAAAATGCCGAGCTACGCGCCGTAAATCTACCCCGGCCGCAACGCGCCGTAAATCTACCCCGGCCGTGGGCGAGCTCAAGTGGCCTAGTTCGGCAAAGACCAATCTTATCGATTTCTCCTAACAGATGAGTGAAGCCAAAGGCACGAGAATGATGACTTCCACACGGTTCGGTAGAGCGCATTTACACTTATGTACCCTTTGCCGGGCTGCGTTCAAAACCTAAAAATTTGAATGCGCGTAAGACCTGGTGCATTGGGTCCTGAATTATTTCGACAAAACATGGTGCATAATCCCAATATTGCAATTTTGCAGTGAACTTGAGCACAACAGCTCCGATGTTCCGAAAAACTTCGACGCTCGTCAGAAATGGCCGAATTGCCCGTCAATTTCGAATGTTCCAAATGGAGGATGCGGGAGTTGCTTCGCGGTCGCCTCGGCCGCCGGTGTGTCGCCACCGACCTTGCCGGTACTCACTCGAATGGAACTTTTAAGTCACTTTTGTCCGAGGAGCATATTATTTGATGCTGCTCGGAGTGCGGAAATTGGTACGGCGGAGATCAACTGAAGGCCTTGACCTATTGGGTTAATCAGGGACTTGTTACAGGTAAGCGGTGACGTCATTGGCCTAGGAACCTTTGATCTGCATAGATGTGAAATTTTATTGTTATCACGCAATTTGTAATAATTTCTAAAAAACTGTAATTATCGATTTTTAAAATTAACTTGTTCCAAATTTTGAATCAAACGAATTTTCTAGACGCGAGATTTTTGCAATTTATCGATTTTCGCAGGCTATTGAGTTTTCCCACAGTAGTCGATTTTTCTAGAAAATTATCGATTTTTAAATTTTTTTACCGCATTGATTTTTCTAGAAAATTAACGATTTTTCTAGAAAATTTTCGATTCTAAAAAAAATAATCGACTTTTTTCTCAAAACTATCGATTTCTGCAATTTATCGATTTTTTGAAATTTATCGATTTTCCCTGCCAATTAGCGACTTTAAAATATTCCCCAAAAATTTGAACGAGTTTTCTAGATATTATCAACTTTTGCAATTTATAGATTTTTTTTTTGCAACTTATCGATTTTTTGCAAATTATCGATTTTTTACGGCTAATTCCTTATCGAGTTTTTCCAAACAATAACGATTCTTCTAAGCCCGTGGAAGCGTTTATCGAAAACCTAGGCCATCTCTATTTTCCAGGTGGCCGTGACGGTTGCCGTCCCTATTTGACCTGTCGTGTGGCTTCAGTCCAGTGGTCGCCGGCCACGGTCTTTGAGGCCGAGGTTCGAGAAGACGGACATTCGTATGAAGAGGTGTCTGAATACCTCTTACCAGCAGAAATATGAGGACCCGGATAAACATTTTGGCTAGAGATATTTTTTTTTAGAAACTAAATAGAGAAAAATTTCTGGGATCTATTCAAAAATGGCAAACTTTTTGGAAATTATCGATTGTTTCCGGTAAATAATCATCAATTTTTTTCTCGGAAAATCTAGATTTTCGGAGATTGACCGACATTTTTTTCGAAAATTGTCGATTTTTTCCGTTAATGATCGATTTATTCGGAAATTATTGATTTATAGTTCCGATAATTATCGATTTTTCGGATAATTATGGATTTTTTCCGATAATTATCTATTCTCCGGTAATTATCGATTTTTTCCGATAATTATCGATTTCCCTTTCCGGATAATTATCGATTCTTTTGGCCGATAGTTATCGATTTTCCCGATAATTAGCGATCCGGTATTTATCGATTTTTTCCGATAATTAACGATTTTTCCAATAATAATCGACTATTCTTCCGATAGTTATCGATTTTTCCGATAATTATCGATTTTTCCCTTTCGTAATTATCGACTTTTCGGGTAATTATCGATTTTCCCGATAATTATCGATTTTTCCGGTAAGTATCGATTTTTTTAATTATCGATTTTTCCGATAATAATCGACTTTTCCGATTGTTATCGATTTTTCCGATAATTGTCGATTTTTTTCGATAATTATCGACTTTTCGGGTAATTATATTTTTTTCCGGAAATCATGATTCCTATAATACATTTATCAATTTTTTCCGATAATATCAATTTTTCCGACAATTATCGATTTTGGTTATCGATTTTTCGCTTCCTATAATTATTGATTTTCCCGATAATTATCCATTTTTCAATTATCTTTTTTCCGATAATTATCGATTCCGATAATAATCGACTTTTCCGATAGTTATTTTTCCGATTTATCGAGTTTCTTTCGATAAATATGCGACTTTTCGGGTAATTCTAATCGATTTTCCCGATAATAATCGATTTTTCCCGTAATTATCGATTTTTTACGGTAATTATCTTCCGAGACTACTCGACTTTTCCTTACGATACTTATGGATTTCTCCCATAATTATCGATTTTTTTGGCCGATAATTATCGAATTATTGCGGGCAATTATCGCTTTTTCCCGACACGATAATTATCGATTTTTCCGATAATAATCGACTTTTCCGATAGTTATCGATTTTTCCGACAATTCGATTTTTTCTCCGGTAATTATCCACTATTCGGGTACATTTTCGCCCGATAATTATCGATTTTTCCCAATAGGTAATTATCGATCTTTGCCGATAATTATCGATTTTTCCGAATAACTTTTCCGATAGTTATCGATTTTTCCGTATCTAAGATTTTTTTCCGATAATTATCGACTTTTCGGGTAATTATCCATTTTTTTCCGGAAACGTCATGAATTTGATTTCCAAGTAATTATCAATTCCGAGAACCTAATTATCAATTTTTCCGATAACTATCGATTTTTCGGATAATTATCGATTTTTTCCGATAATTATCGATTCTCCCGATAATTATCGATTTTTCCGGTAATTTTCGATTGTTTCTGATAATTATGAATTTTCCGATAATAATCGACTTTTCCGATAGTTATCGATTTTTCCGACAATTAACGATTCGATTTTTTTTCGTAATAATCGACTTTTCGGGTAACTTATCGATTTTGCCCGAGCATAATTATCGATTTTTCCGGTAATATATCTATTTTTACCGATAATTATCGATTTTTCCGATAATACGACTTTTCCGATAGTTATCGGTATTTTTCCAATTATCGATTTTTCGATAATTATCGACTTGCATTCGGGTATAAATTCGATTTTTTTCCGGAAATAATGAATTTTTCCAATACTTATCAAGTTTTTCCGATAATTATCAATTTTTCCGATAATTATCGTTTTTCGCGATAATTTACGTCGATTTTCCGATAATTATCGATTTTTCGGACCATAATTCTCGATTTTCCGATAATTATCGATTTTTCATACGATAATTATCGATTTTTCCGATATTTTTTTTCGGAAATGGCTGCGCCATCGCGGTTTGATCTACAAAAAATGCGGAAAATTTTAGCCCAAAATGTGACCTCAGCACGTTCTTAACCATACGAAATCAGTTGAGAACTCTGCCGCATTTTTTGTAGTTCTACGTAGATCAAGCCGCAATGAGACACTCTGGGACCAAGGGTCTGTAATTGACTTCACGGGAAATGATATTTTTATTTAATGCGCAAAACTAAAATTAAAAATTTCGTTTCGACCAATACACCATTTTAAGCGTAAATTTCAATTCAAATTTTTGCAGCCAAAGCTTTGGCTATTCAATGTATCCCCGCTCAATGACAGTATCCCTTACCGATGGAAAGGAACGAGTAAAGGTGCCCGAGTAACTATCATCGGTCACTTCAACGAGAAAACCGAGAAGCTGAACGTGACCGAGTACGGTGACATCATGACAAAACAGAAACTTTATGGTCCAGACACCACGATGGCGTTCCGACTTCCCGAAGAATTCCTTCATTATTCGAGCGGAGTGTTCCGCCCGTAGCGAATCCACCTGATGGTTTCGACGATCGAAATATAAGTGTGTTGGCACGTGGTTGTTCGATTGATCGGGGAGAATCAGATGATGGAAAACATTATTGGTTGGCTGTTAATAGTTTTGGTAACCATTGGGGTATAATGGTGATGCGTTATGGCAAATTGCGCACGGCCCGGCAAATGGTACATCCATACAAATACGCTCTGATAATTCGGGGTAAGTTTAGCCAGGTTTGGTTTTAAGGAAAACGCGTTGGTCCAAAAAAGTTAGAATTTGATTTCGGACATTTTTTATATGCATCACAAAAATGGACAAGCTTGAGAAAAAGCCCAGGTATAACACCGGTATACAAATTGTGTACAGGTGCCACTTCCCGGGCCGGGATGCGCGTTAAATATAGTGCTTTTTAAGAATGCGTGTTGCGCAACATATTTGACGCGCAAAATCTCGTAGCGAAAGCTACAGTAATTTATCAAATTACTACTGCAGCGTTTATGTCGCTTGTTACGGGCTCGAAAAAAAAGTTACCAGGACATTCTATTTTTTCTGATTTTTTGCTTATTTTTATATAGGAATATTCTCACGGTGTGTCATTCTGATCCCATAACGGTTTGTAACAAAGAATGCGGGAATTTTTCGCCCAGAAAAATGTGACGTCAGCACGCCCCTATCGATACGAAAGTTGTTGAGAAATCTGCGTATAAAATCCCGCATTTTTAGTAGATCACGCCGGGGAGACACTATGTCACCACGTGTATTCTATCCAAAAATAAATTATTTCAAAAATAGAAGCCCGAAAAAAAAAATCGACAAAAGCGCTACAGTAGTCATCAGTTAAAGCGAATTACTGTAGTTTTCGATACGAGATATATTGATATTTTGCGCGTCAAATATGGTGCGCAGAACCATTCTTAGACTTTTGTGTTGCCGTAAATAAATTTGGACGTCAAATACAGTGGATATTGCGGGCGATCGGCTACAATGTATTGCGAAGTTTATCAAGAGTGCGTCAAAAATATGATGGAGCCGCATCGGTCATGTTACAAAACACCATATTTGACGCGCAAAACTTTAACTTTGGACAAAAAGTCAGAGAATTAGGATTGCGTAAAAAACTGGCATTTTTTTTCAGAACATTTCTGAAATCAGTTTTATATTCTCAAACCTTTCGCGTCAAATATGGTGCATCAAGTCCCGAACCAAATACACTCTAACACGTAGTGCCAGGCTGTTCCCTATTAGTTTGACCTACAAAAACGCGGGAATTTTTCGCCCAAAAAAATGTGACGTCAGCACGTTACCATTGCAAAATCAGTTGGAGAACTCTGCGTCTCCTCTTCTCCCGCATAAATTTTGTAGATCAACGTGATTCAGGCCGAAATGTGACACTCTGACACCACGGCCCTAATTAACTCGTAAAAATCACCGTTTTTTTTCCAGGACTCTTCAAAATCAACCCAGATGACATGGAAAAATATGGTCTAGAGTATGAAACAGCAGTCGTCTAATTAATTGTTAATTCGGCAAAAATTTTTTATAATTAGTTAAATATTGTCCACCTATGTCATTCCCGCCCGATTGCATCACACCTTGTCCCATTTCCGACAAAAATCAATTATATTTATATTCGGCCATTTTTTTAGCTCACTCATTCCATAGTTTTTTTTTAATTAAATTTTGGATGCTAAAATTTGCCATTCTCATAGACATTTTCAATATCTGTGTAAGATAAATCTTTTTTCTGGTCTTCAATTGATGGAAAAAAACAAAAAAACAATGCGCGTCAGGTTTGGTGTATTGTGTGCAAACACCGAGCGCATATTTTAAAGGAAATTTATTTTTTTTTCGATTAAAGTTGCTGATTTTCTTTAATTCTTAAAAATGTAGGATTTTGTGCCAGAAACCGAGAAAATTGAAGAAGTCCTTGTCAAAAAATCGATGAAATCCCTGAAATCCCGGCTCCTTCAAGCAATTATCATCGACCAAAGTAAAATGCTGACTTTATCAATTTTCAATTACTTTTGCATGCATTTTTTCTAGGTTTTTCTCGAAGAATTCTCAACAAAATGGTACGGAAAGTACGGCGAAGATGGGGAACTTCTGGAGCACATCGACGAGGACTGGGAGCCCGTAGGCCTCGACGGTGAAATTTCTGCGCCTACTGTGGTATGGGCAGGAGGATCAGGAGTAAAAAGCTCATAGGCTCTATGATTGGGATGAAGAAAAGAAGGAATGGGTGCTGAGGGAGGCCAAGCAGGAGGAGTCAATGAGGAATCACAGAGTATCAAGCGAATTTCGGAACGAGTATGATGATATTTATAAAAAAATGGACGAAGAATTGCAAGAAAAAGCGGCAAAAGCTCAAAAAGAAGATGAAGAGAAGAAAGGGCAGAAGAAGCGTAAGAAATAAGTAGGCTTGGGAGGCGGGTGGAAGGCGCTAAAGAGGTCTGGTTGACCTAGGAGATAAGGTTCATGCGGTTATGAGTGTGTGAAATCTTCCGGAAGCTATTACAGACCAGGAATTCCAGAAATTTATGCCAAGTGGAGTTATTCAGCCGGCTATTCGAACGAATAAGCCGAAATGCAATGGCTTTACCGGGAGGAAAACGGCAAACTCAAAGGCGGGGGACGGATGATGTTGTTATATTAAGAAGGAATCTGTCGAGCTTGCCTGTCACATTATCGATCGAGCGAGCTTAAAAACGGGAAAGTGAAGGTTGAGGAAGCTCGATTTGAGATGAAGAGTCTGATCCGGCGAGGAAGCGGCGGAAATTGACTGCGGCGCAGAAAAAATATGGAGCAGCAGAGTAATAAAAAATATTTGGTGCAAAATTTGAAATAGCTCCTAAATCGACATTAACTAGGTGAAAGAAAAGCCCAATGAAAAAAAACCAAAAAAAATCGTATTACGTGAACACAAAATCCTGAGAATGCGTACTGCACAACATTTTTTTTTTGTTTGACTCGCAAACGGGATATCTCGTAGCGAAAACTAAGACTACTGTAGCACTTCTGTCGTTTTACGGGCTGCTCGATCGAAATGATTTAAAAGAATTTATTTATGGGATATTTAAAGTGGGCAAATATTTACCCGTAATAGGAAAATAATACAAAAAAATCTAAAAAATTTATTTCAATAATCGAGCCCGCGTAAATCGACACAAGAGCGCTACAGTAGTCATTTAAAGAGTACTTTTCGCTACGAATATTTTGCTCGTGAAATAAGTTGTGCAATACGCATTCACCGGTCAGAATATTGATATGTTCCCATAATATTTCTACCCGCGGAAAAAATTGGCCCAAATCGTGGATTGTTTGAATTTGATGACAAATGGCTTTGAAAATCACAAAATTTCAGAGAAAAATTTCGATTTTTGTTTTAAAAAATCAAAAATTGACTAAGAACCCAACAAAATAGTTAACTTGAAAACATGTCTCCTGAAAATCTTAGAATTTTCAGAGTTCACCCGAAAAATACCAGATTTAACTGGATAATTGCGAATTTTAGTGAGCCAAATTCCTTTCATTTTTCAAATAGAATGTTAAAGTTAAACTAACGACACAAAATCAAATGAAATTGACTAAAAAACTATTGAATTTTGTATAAAAATCCAAAACGATTTTTGTAAATTTGCAACAAAAATATTTTATTTTAGCATTTATTTATTAGTTCTTATAATTTTCACACTAAAAATTACGAAAAAAGACAAAAAAATTTTTTTCATTCAACAATTTTTCGGGCTAAAAGGTGTAATTTTTGCAGAAATTGAAAAATTATTAAAAATCGTAGAGACTAACTGACAATCAATTTTTTAAGGACCAAAAAGCCAACTTTTGCCGTTTTACTCTTTTTCCGTGAAAAATCCGGTTTTTTTTATTTAATTGCGAAATCACTTCACACCTAAAAGGGTAATATGCTGGTCTCGACACGACAATTTTTTTGTTAAATTCTTAAAAAGGTGTGCGCCTTTAAAGAGTACTGTAATTTAAACTTTACGGAATTTTTTTTTGATTTTTCAAACAAACCACGAAAAATCGTAGAAAATTCCACAAAGTTTGAAATTACAGTACTATTTAAAGGCGCATACCTTCGAGACTTTCTTGTACAAAAAATATGTCGTGTCGTGACGATTACCCTAATTTTTGGCGTAAAAGTCGTAAACTGTCCGGATTTCACTACGAAATTCAAACTTCGAGGAAAATATACGAAAAAAATACACTTGTTGTTTTGGTTAAAATATATTCACTTTTTTTCTACCATTTTTTAATAATTTCACGAATTTTTCCCTCAAAAATTACAAATTTCAACCAAAAATTCTGATTTTTCCTTTCCAGAATCTTCGAATGGACGCCCGATAATCCACGTAACTACCGTCCAAAGTCGGACTGTACGGTTATTGTCAAAAATTGTTCACTCAGTAAATGATGAACAAGGATGCGGTGATGTTGGTTTGAAAGAGGAAAAATGACACATAGTTGTCAGAAATATGGGATTGTTAAGAAAGTCGTCGTTTATGCGGTTGGTATGAAATTTGTGGAAATTTCGATTTTTGGCAGGTAAAAGAAATCTAAAAATGCTAATTTAAAAAAAAAAGCTTTCAAAAAATGCTAATTTTCCAAAAATTGAAGCTAATTTTGGAAAAAACCCAAAATTTTTTTTTTTACAAATGTTTCGATATTGTCATAAAAAAATATAAAAACGTGATCAAAAATTTGAAGCTATTTGTCGGAAAAATTTTTAAAAATGTAAGGCTAATTAAAAAAACCCAAAAGAGGTTCTTGGATTTAACAAATTTTCAAAAAAATTGTCCTAAAAAAGATAACCTTTAACATTAAAAAAATTATGGCTATTTTTCGAAAAATATTAAAAAAACAATTAGTTTTTAGCTTTCCGAAAAAAAACCGAAAATTTGTGGAAATTGTCGATTTTCAAAAAAAACTTATTCTAAAAAAAAATAAATTTTTAACATTAAAAAATCTATCTTTCGAAAAAAACACCGAAAATTTTTGGAAAGTTCGATTTTCGAAAAAAAAGTATTTTAAAAAAACAATTATGAGAAATGGTTATAAATTGTTTCAAAAATTTTTTACAGCTATTTTTTTTTAGAGTAATTTAAAAAAAACAATTTAGCTAATTTTAAAAAAAGTAAAGATAATTTTCAAAACCCAATATTGAGGATTTATCGATTTTAATAAATTGTTCAAAAAAAGCTAAATTTAAAAAAATTATTGAAATTTTTAAAGAGGGTTATTGGATTTTTAATTTTCAAAAAAAAATCATCAAAATGTATAAATAAATAAAGACTATGGTGCTTATTTCGCGAAAAATTGGAAAAACAATTTTTAGCTAATTTACGGAATTAAAACAACAAATAATTTCGGAAAATCGAAAATTGTTGGTTTTTTTTTTCGAACGCTTTAAAAAAATCCAAAATCATCTGAAAGACATTTTTAAAATTTCCAAAAAGAAATTATGAGTATTTTTCAAAAATCAAATCGAATGATTATCTACCGCTTTGTTTGACATTTTTTGAAATTTGAAAATCATTAATTCATAAAATTTTTATTGAAATAATTCAAATATTTTTATTGAAAAAAAACGAAAATATTTTCGCTTTGGAATATTTCGGAAAAATCGATTAAAAAAACAAGTAAATAGGTCAGTTATTTTTCAAGAATGCTATTTTTTGGAGAAACCGCTGATTTTTTGTCAGTTTTGTCGATTTTCGTTGTAAAAAATTAAAAATTCAAAATTTCTTATTAGGAGTGCACAAAATGCTGAGAATGCGTATTGCACAACATTGACGCGCAAAATATCTCGTAGTAACCATACAGTAATTCTGACATTAAGTACTGTACTAAGCGTCTTCGGAAAAATTCCACTTTTTTCAAAAAAAAAAACGAAATATTTAGTTTTTATTAAAAAATCGAAAAATTTTGATTTTTTAAAGTTAAAAAAAACGAAATATTTTGATTTTTTATTTAAAAATGAAAAATATTTTCCAACAAAAAAGGCTCCTAATTAAAAAAAAAAAATTTGCGCTTTTGATACAAAAGTGCAGATTCTTGTCTTAAAATTTAAATCAAAAATTTTTAAATAGACTTTTAATCCATCAAATTTCCCCAATTTTCAGGACCACCCGGACGGCGTCGTATCGGTTACCTTTCGTGCAAAGAAGAATCGGATATGGCTGGAGGCTAAAATATCTTCACGGACAAGTAGTTGAAGGTCGGAAATTGACAGCCGAGCTCTGGGATGGCCGGACAAAGTTTAAGTCGAGGAGACGGAAGAGAATGAGGGCGTCGGAAGGAGTACGAGAAGTATATTGTGGGTGAAGTAGTGAGACGAAGGAGGAGAGGGACGACGATGATGACGGCGAAGATAATTGATTGATCTAAAATTTTTCTGAAAAATTATTTTTAGTTCATACATTTTTCCGAGAGGAGCAACCGGATTGATCAATTTTAAAACTATGTTCAAAATCGCCCAAAATTAAAATTAGTGAACTTCCGTTTTCATGGATTTTTCGAAAATTAGCTTTAAAAATGTTTGCCAAATTTTTCGACGATATCGCGATGTTTTAAAAAGTTCGAACAAAATTTGCCTAATTTCAATTAAAATCCCTTTTTTCGAAATTTTCTAATTTTCTGGGCCAATTGGGCCGTTTAAAAGAAGACTAAGAAAAATGGCCAAAATTTGAGAGTTCAGCGTTAAAAAAATTCTAAAATTTCAATCAGACTACGTTTCCGGTGGAAAAAAATTTTCTTGGAAAATTGCTTTCTTGTTTGAAAAATTATTTTAGTTTATACATTTTTTTTCCGAAAGTAGGAACAACCTATCAATTGAAATTTTCAAAAAAAAATAAATTTGAAAGCATGTTCCGAAAAATTACGTGTTTTCGGTTTTCTGGAAAAAAAAAACGAAAAATTTCACCAAAAATCAAATATGAACATACTTTCCTAAAAATATGAAAAAACCAGAAATTTTCTTAATTTCCCTATTCAAAAAAATTCAAAAAAAAAACCAAAATTCAGTTAAAATCCCTTTTTTCGGAAAATTTTAAAACTGCTTTTCTGCGCCATTGTGTCGTTGATTTCAAGGAATTTTTTTCTTAAAATCCGTGAATCGTTTTGAAATTAAACAAGAAAATTTGAAAAATCAAAAATTATTTTCACGAAAAAAAATCAAAAATTTCAATCTTACGGTTTATGAATCCTAACTAAAAAAAAAATTGAAGTAACGAAAATGTTCAATTTTTTCGAAAATTTTCGAGGTCATTTAGTTTTTTCTGTGAAAATTGTATTTTATACGAATACTCTTTTAAATTAATTTTTATATATTCCTTTCCCGAAAACTTCAATAAAAAAACCCAGTGATACAATTAAAATCGAGATAACCACAGTCAAAGTGGCAGTAAGCAGGCAAAAGCACATATTAAGGGAATACAAAATTACTGATAGCGTAAGTCTCATCGCGCTCAACAGATTTGACGCGCGAAATATCTCGTAGCGCAAACGATAATTCGTTAAATGGATACTGTAGCTAGTGCCGATTTACGGGAATCTTAAGAACCTAAAGTAGCAAAAATGGAGATCCCGTAAATCCACACTAACACGCTACAGTCTATATCCGTTTAAAGAATTATTGTAGTTTTCGCTACGAGATATTGTGCGCGTCAAATATGTTGTACAAGAACTACGCAATTTTAAATTTACGTCATAATATACACAATTAACTAGTAATGGATCTACAAAAATCTACAAAATTTCTTCATCAAACTCACTCTTCCACAGCTCGATCGTCCATGAGTCTCCTCGTACGCCCACCAGAGAGCACATCGCCACGGTGCATATTGTCGAGACTTCCTCATTCTGATATCTGTGACGACATGCGTGGCGTAACTCAGGTTATCCCTCGCAACGACTACCGACGGACGGCCTCATCTGCATGGGACGAAGACGGTCCACGTTTCGAGCGTTTCCATCCGGCTTCGATCAGTGCGGCCGCTTCGATGACTGAATGAATTTTTATTTCAACTTTTGCAGAAAAAATTATATTTAGCAAAATTAACGGGGAAAATTGGCTGTTTAAAAAATATTTATTATATTGCGCGTTTAATAACAAGTCCAGATGAAAATTCTGCAAAGTTTGAAACTTAGTACCCTTCAACGGTGCACACGTTTTAGAATTTAGCACAAAATTGGCGTGTTCACGATGCTTTTTGGTTAAAACATTCAAGAAAGTGTGCGCCTTTAAGGAGTACTGTAATTCAAACTGGCTGATTTTTCATCGATTTTTCACTTTTTTTCCAATTAGTAAATTTGTGTTATTGCAGATTTTTTAAATCATTCATACCAAATTTTCAATCGAAAAATACAAAAAGAAAAAATGTAATTTCGTTATTTTCAAAAAAATAAATTGAAAAATTGAAAAAAAATCCAAATATTCGAGTATATTTTTTGAAAATAAAAATGAAAATCGGAACAGATTGTTTTTCGATTTTCCAAAAAATTTAAGACATTTAAAAAATCTAAATTTTCGATTTTTTAGAAAAAAAATTAAAAATCGCAAAAAACCAAAAAAAAATTGGCTGATTTTCCATAAAAAAAAGGAAAGATAAACAAGAAACAAATATTTCAAAAAAAAAAACAATTTTTTCCGATTTTCGGCAGAAAAACAACTGTAAATCGGAACAATCATAATTTGTTTTTTCTATTTTTCACAAAATATTGAAAAATAAAAGAAAAAAGGAAATTTTCGATTTTTTTCCGTTCCAAAACAAAAAATTCATAATCTCACAATAACCAAAAAAAAATGAAAAATCAAATAAAAACGAAAATTTCGTTATTCTCAAAAAAATAAAAACTTTTTTTTCTTCCGGAAAATCTCAAAAACACTGGCAAAAATGTCGGGTGACGAACATTAATTTTTTTCTATTTTTTTGGCCACGATGTTTCGCGAAAAATTGTCAAAAATTAAAATTTTTATTTTTAAATCCAAATTTTCACTTCCCCCCCCCCCCCCCCCTCACTAACAACTTTCCGACATCTTCACAATCTCCATAGCTTTCTCTTTAACCTCCGGCCAAAGCGGTCACTCAGCTCGCGGAGCCACCTTATCCGAAAACACAATCGTTCCAAGCTTCACCACGGCGGTCTCACCTAGAACTCCATCGACAACGACATCCTCTCCAAAATGTTCGCCGATTTTTCGATTCAACGAGCTTCGCCGTTCATAGCACGTGTGTGCGAGCTTATCACCATCGATAACATCGAAATTATGCGTTTCACGGAGATATTTCCCGATATGACTTTGACGAAATTCCTCCGGCGAGCCCAATGATGTGCGAGGTGCCCGTTTCTCTAGGAACCACCCGAGCTGGACGGAGCATGTGACCCGGATCCTCTCTTCGTCTGGAGCTTGAGCTGATCTTTGTCTCTTTCAGGATCTCATCGGATCCTTCAGGCAGCTCGACAATTATCACATCCAGCTGCGACATTCCTTGCTCATTTCTCTTTTTGTTCGAGTACCGCATTGGCACCTTTAATAGTCTCCCGGGACACTACTAGCGCTTCGAGGTTTTTTATTTGAAGGACCGAATGGTTCGATTAAGATTGGCTCCGCGAAACATTTTGCCTGGAAAATTATGGGGGTACTATTGAGCAAAAATGACCTGCATTTTTGGAAAATTAGAAAATCGGAAAAAAAATTTTCGTGCCGAAATTTTTTATTTAGAAAAGTTTTTTCTAAAAACAGAAATTATATATTTTTTCAGTTTTACAAAAAATCGAAAAAAAATATTTCGATTTTTCGGATTTTCCAAAAGAAAAAAAAATATCGAAGTTTTTTTAGATTTGCAATAGCCAGCAAAAATTGATTAAAAAAAACCGGAAAATGTATTACGGGAGAAGATTCTGAGCATACGTTGAACAGCATATTTGACGCGCAAAATATCTCGTAGCGAACACTACAGTAATTCTTTAAATGACTACTGTATCAATCAAGCCCGTAAAGCGCTACAGTAGTTATTTAAAGAATAACTGTAGTTTTCGCTAAGAGATAGTTTGCGCGTCAAAGATGTTGTGCAATACGCATTCTCAGAAATTTTGTGTTGCCTTAATTTTCCGTTTTCAATTTTTTCTTTTTTTGAAAATCTGAAAATTTCGATTTTTTCCAATTCTTTTGGAAAATCCGAAAAATCGAAACAAAAATTTTTCTATTTTTTAAATTTTTTTTTTTGGAAAATCGGATAAAAACCAAAATTTTAGTTTTTTAAACAGAATATTTCATGGACCAAAAATATCGATTTTTCCTAAAGTTTTAGAGAAAACTGAACAATTTAAAACGATGTTTATTGTTTTTATTTAAATTTTTATGGAACAACTTTCGATTATTATTTTGAAAAAAAAGCTTTTTTAAATTTTTCTTTATTTTTGGAAAATCGAACATTTGCTATTTTGCGATTTATTAATTTTTTTGTTGGAATTTCTAAAAATCGATGTTTTATTTTTTCAAAAATCAGCGGTTTTTCCGAAAAATGGCAAAACTTTTTTTAAAAAACATTTAGTTCTTTTCCTATTTTGGTTATCGAAAGATAAATAATTTTTTTGGCAATTTTTAATGAATTTTTGATCGTAACCTCTTACAGTCCCGGAAATATCAGTCCTGTACAGAATCGACAACTGCTTCTTAACATCCGAAACTCCGCAGCAGCTCAATCATCTAATAATGATTGGAAAAAAACCAATTTTTTGTTTTACGAAGCTATCATCTAACCAAGAATCATATCCTGATTTCCATTAGGTGACCCCCACGACAATAAAATCAAAAGCGAGCTCGGCAGCCATGTTGAGCAACACTTGGTGCCCATTGTGAAGCGGCCGATCGCATGTGCCGCCAACACAGACTTTTTCGTACTTTTTCGCCGCCGTTTTTCCGCATTCTCCAGCAGCTTTTCCTCGCCGATCACATAATGATTCTCGGGATTTCCGCGGATTTCGGACACAACTAGCCGGACGTAGAGCTTCGGGCATGAGTTCGCCGATGTTGATTTTCGAGACTAGCTCGTCGGTTCGCGGCTCGTCCGGGTTTAATCTTGCAGCAACAGGAATCCTTGTTCACCTTGCATTTTCGAGCCGGGAAAAAGCCCAAAGCACTCTACCTCACATAAAGCTTCGAGCTTAACGCGGCGGCCGCAGAAGTGTGCAATTGATACAGTTTTCATTTTTGCTATTTAACACGAGAAGTCCGTATTTCGAGCTGATTTAGAATGATGAGAAATATAAGGGGATTGAATATTCCTCAAATAAATAGAAAAATTCGCTGCCACGTTCGCTGCTCTTATCGGCTGCGCGCCTCTATTTCACATACTGTCTCTTCTATCTCTCCTCTCGCGAATCTCGCTCTCTAACGCGTGCCGTGGAGCGCACTTCGCTCCTTTTTGCTGGAAATCTTTCAGACATGCCGGAAACAAGAAAAACAATAAATTATTGAACGGAAAATAAAGTAAACGTACTCATCGTATTTTTAGCTTCATAAAAAGATCTCTTAGAGCATATAATATTGCTTCTAAACACCAAATAGTAACATCGCTGAAAATGTTGTGAATTTTATGAAAATCTAGGATCATTTTTCCCATTGTTAGTTTATGAAAAACAACAATAAAATGAGAAAGATTACATGGGAAAACCGAAGAAACTCTCGCGGTCAAAATTCGAATAGAATTACTGTATTTTTCGGTCGGGCGCTCACGGAGATATTTTGCGCGGGTCAAATATGCTTGGCGCGGCGTGCATTCTTCTTTCAGCGTTTTTTATTTAGTAAAACAGTAATAAAATGATTAAATGCATTTTGTGTGATTTTCAGCCCAAGATGTTTAAATAAATTGTTGTTGTCCAACTGCCAGCCATTTTTAAAAACTTAAATATATGGGAAAACCATAAAAATGAAGACAAAAGTTTAGCATAATTTTGGAACTACAGTACTCTTTAAAGGCGCAAGCCCTTTAAGACGAATTTGTCGTGTCGAGACCGGACAAATATTCAAAATTTCTTCTATACATACGCAGATTTAATGTACAGCAGAATATGAGCATTTGCACATTGCGCAATTGCTAAATTTTTTCAAGGATCACAATAAAAATTAAAAGTAAACCAAAATACTTTATTCAATACCACAAATAAGTTCATTTATCTTAGTCAACCTCTTGCCGACGTCGTAGCTTTTGTTGTTGCTTCCCCTTCTTCTTAGACATCTGAAATTTTCTCATATATGGAACGCGCTCCGATCTAACAAAAAACCTTCTACTTTTGGATTTTCTTCTTGTCTACATCTTCCTTCTTTGGCTGCTGTCCAGATATTTTTGTCCCCCGGCTCCCGGATCGCTCTCAAAGTCCATCTCCGGCTGCAGCCCAACCTCAGGCGGCGCGATCATCAGTACCTGCTGTTATCCAGGACCCTTGAAATACGTCATACAATCCCAATCTGGTGGCTCCTGGGTATTTGACTTATCTCAAACAGCTTCTCGCTGGATCCCATCAGCGATACGATCGTACTCCACAACAACTCAGCGACATCCTTGGGCTCGATGATGGTCAGAAGATCAAGAACCCTGAAGTAGTCTCCGGAGTGGTTCTCCCAACCGACGCGACCATCTGGTGGGTGCAGTGATGCGACGTTTCACGAGGAGCACGTCCTGTTCGCTTTCCTTTTTGAGCAGTGCCACACATGGGAGAGCCGTGAAAGAACCCGAGCACCTTATGTACCACCAGGACTCTGACCCATGTCGTTCCTTGTAGCCGAGATTTTCTGGGAAGAAAAACGTTGTCTTAAAGAAATTGTGAACGGTAAGGTTACCCCCTGGTGAGCATGAACGCTCGCGTACTTGACCACTCCTCATGTAGTGAATCCACTCTTTCTTCCATCTGCTCCTCAGCTTCGTCGTTCATCTTGACGAAGCAGTTAATTTTAAAAAAAGTTTTCGGGGTAGATTTACGACGCGTTGCGGATCTGACGCGTCGCGGTTCGATTTTTTGAAAAACTAAATGTCACATATTTGTCCCTGTGGAGTACCGAGCGACTTTCCCACTCAAAATAGGATGGAATTGAATTCGGAAGTGTCACCGTAGCAACATTCGGATTGTCTGAATAAATATAAAGTGAGATTTTGATTTTTGCTCCACTGATAATGGAGTTTTTTTTAGAAATTCTGCAAACATTAATTTCTAGAAAATTTGAGTTACCTCCAAAATTTTTCACAGAAAATTTGAATTCCCGCCAAAATTTTATTCTCAGAAAATTTGAATCCAAAATTTTTTCTCTGAAAATTTGATTAATTCCCGCCAAAAGTTTTTTTTCAGAAAATTTTGAGCCACGGTCGCATTAAATTTTTCTGCACTAGGCTATTTTGTGGCAATACCAGGGGTTGTGGTTTACGGCGCGTTGCGTGTCGCGTCGAGGAGTTTAGTTGTAAAACTAAATGTATTTGTCCGTGTGGAGTACACGGAAGACTTTCTCTCCACGCGTAGTTCCTCAGCAATTGTCAATGGAGCGCAAAAACTGCCGACCCAAATAATTTTTGCACTTCATACACACAGCAGCTCGCGGCGTGGCATGAGGCCCGCATTTCGCGCCTCACTGGAAGCCCCAGATGCCAAAAAATCTACCTGTCAGCGGTCTCTCTCCACCGAAACCCAACAGGCTGATGGTGCGGTCCGTCAATCTCTCTTCCAATACCGAAAGGCGATGGCTTGATGTCGCGAATGAATCCATTCCGGTGGAAGTCACGAATCGCGGATGGCCAGGCTCGGCAAAGTGAAGACCTGCTGAACTTGTCCATGTTCATATTCATCATCAGCTCGTATATGGAGGGCCATACTTAAAAATTTGGCTTAGCCAACGAAAAGTGGTACCAATGGACCACAATGGAAGCGATTTCCGTGCCACCTTCCTCAATATTCGTGTAGAAGATGGGTGGTGGATCGACGCGAGGACAACTGACTTTTGACGAAGAAGCTGGAATTTTTTTTGCTCTCTAGAAACGGTTTTCACGGCGGCCGTCAATTCCCGAGTTTGGAAACTCACTTCGTCATGTTATTTTATAATGAGTGGCTAAACTCGGAAATTGTCGGCCGTAAACCACAAGCCAGTTGGTTCCTTCGCCGCGACCGACACTTTCCGGGTTCCGCGCCGCCCTATACAGAAGGCTGGCTGCGCGAGGCAGGCTTGACCGCGGCAGGTGTTTTGGCGTGACCGCTGCATGGACCTGCTAGCTTGTCAACTAGGCAGCCTAAGCGAGCCTGCAAAAGGTAGGCAGGCGCGACCCTTCTAAAACCGTCCTCGCAACACACAATACCTCACTCTTCATGTTTAACGCCATTTGACCGCAAAAAACTTCCCATCACTCTCGCGTTTTACCTTGTGAATCGAGCCGGACGTGCCCGTCGCCAGCGGTTTCGTGACTTCATAGGTGTTTTGTGCTCGAATGAGCTCCTTTTGCGTTGTCCAGGTCCGATAACTCATTGATTTAGAACACCGAAATGTCACGATTATACGCAGTGAATCGCGTAAATAATCGAAAATGAGACTCGAGTCGAAACTTTTCGAAACCTGCTAGATTTTCTTTGTAGGGTTGTTGGAGTTAATGATGATAATGAGGAGGGGGGATTTTATGTGGATTAAGAGGCTACCAGGAAAATATTTATTTTTTAAATATTTTATTGTCATTCTTTTCTTTTTTAGATTTTCACGTTTCTTATTATTAAAAATAGAAGAGTTTTTCAGTATTTCAAAACGAACACAATCTGAAATTCAGAATTACTACTAAAGAAACGAAAAAAAAACTGAGAAAAATGTTCCAGATTCTCCAGTATTGTTAGGCGTACCCCCCCCCCCCCCCTACCTACCTACCATCCTTCCTAGCCTACATGCATACCTGCCTACCTAGACGCCTGCGGCCTACCTTCCTGCGTACGTTTATGTCATACATTTTTTGCCAGCCTTCTGCCTGTATTTTACGTGTCTTAATTACGTGCCTATCTACTTACCTTTCTTCCACGACTACATGTATACCCGCCTACCTATACGCCTGCGTGCCCGCCTCCTGCCTAACTACTCACCTACCTGTTTGCATACATGCCTGCCTACCTTCTTGACCATGCCGAGGCGCCTATACGACTTGCCTACCTACACGCCTGTCTATTGCCTACCTGTTTGGTTACATGTGCCTGTGCCGTACCTGTGCCCAGATCCTGAAAAACATCGTTATTTTGTAATAAATAATTTTAATAAAACTTTAAAAAACAAAAAAAATACGAAATTAAAAATAACCTAACAAAACGTCTTTTCAAACCCCTTCGTACTGCTTGATAAAAATTCGTGTTATATCCTCTTCAACAACTTGAACTGCACTCCTAATCCGATTAGACACAGCTAAACTTTTTGTCGCTTTATTCATGGACAAGTGCGCTCCTGGGCAATTGAGACTATTCGAATCGGTGTAATAGGTGGTGAAGCTCTTTGAGCATCTTAATGTAGAGTAATCTTCTCGAAGACGGCCCAGAATTGCGGTGATTGAGGGATTTGTGATGGATCTGTACGGGATTTGATGTAATAAATTTAAATTGTGTGGTTTAGATGCAGAAAAAAGTTTAAACTAAGAATTCAGACTAAGACTTGAAAGAGAGCCGATTAAAGAAAAGGGCTGAGCTGGCTTACGATTTTTCCCCCTAAGTTTATCTTCACTTATATAGTCTATTATCCCCCCAATACTAAACAGTATATGGTAATAAATACTTTGACTGCAAGAAAAATGAATAATAGGCTCTGCCTCTATATTTGTTTTTTTCGTTTTAAACCCAAACTTATTCTACGCCGAAATTCTTTGATATTTTTTGGAATTATATATCCTTCGATTTATATTCATGATTCCAGCTCAAATTTTTTTTTCTCAGAAAAATTGAGTTTCCCGCCAAAATGGGTTTCTCAAAAAATTGGAGTGATTCTGCCAAAATTGTTTTTCTCTTTAAAAATTTCCGCAAAATTCTGTTTTTCTCAGAAAATTTGTATACTCCCCGCCAAAAACGTTTTCTCATAAAACATGAATTTCCGTCTTTCTCATGAAATTTGAATTTCCCGCCTAAATTTTACGAGAAAATTTGAATTTCCAGCCAATCTTTTAGAAAGTTTGAATTCAAAAGGCTTTTTTTCAGAAAATTGGAATATTCCGCAAAAATGTTCTGAGTAAAATTCTCTAGCCTATTGCTTTTCTCATAAAATTTCACTTGAATTTCCGGTCACCTGTTTTCAGAAAAAGTTTGAATTTCGCGCAAATTTTTTTTCAGGAAATTTTAAACCTCTGGCTTTATTTATCTGAAAAAAATTAAAATGTCCTGCCATTTTTTTAAAAAAAAAATTCACAGAAAATTTGAATTTCTAAATTTAAAATTCACTGAAACTGACTTCCTTATCGACAATTGTCACACGATCCGATGATTTCAGAGCTACACCGCTCGTAAAAATCCCACGTATTGAATCCACGTCATCAGAGTCGGGAATTTCAAAAATTTTACTATCATCCATTTGTTTGCTGGAAGCGTTAATTATCGATTTTTATTTTTTTATTCGATATATTAATTTTATTGATATTTTATGAAAAATAAAATCAATTTCACTCTCGGATTGGTCTGGCTTTGTTCCTTCATAAAATGTAAAGAAAGAGTTTGCCGAACTAGGCCATTTTGGCTCGGATATCCGGGGCAGATTTACGGCGCGTGGCGTCGTGGCTCGTTAAAAATAGATTTATTTGTCTGTGTGGAGTACACGAAAAGGCACTTCTCACGCGTTGTCAGGCAATTGTCAATGGAGCGCGAAAAATTCAATGAGGAAGAAAGGTTCCAGAATCCCGTGTCCCTGAGTTTTTGAAAATTTTTGAATCGAATAAAAATTTTAATTGAAAAGATCGATTTTAAACAGTTTTAAAATTCTTTTAAAATTGAATTTAATATTAATCCCATTTTAAAAATTATTGATTTTCGAGCATACCTTTTCAATTTGTTCGGATGGTCCCCGTGCTAATTGAGCCAAACACTATCGATTAAAGATGGGCGTGTCACCACTTTTGCCACGCCCCTTTTATTCCGATATTCCAATAACCCGACGAATATCTCTGGTTCGTAATTTTAGAGTTGGCGAACACTGTGAAATAGGAATCGAACGCTTTCGGCGAAGATCAGACCACTCGAGAAATGTGATGAAGCTCCCCGGAGCTCTGAATGTTTGGATAAATAGAGTTGTGAGCCTAGTGCAAGTTGAAAAAATCGATAAATTATCGAGTTTTCTGATTGTTTTAGGCGGGAATTCAAATTTTCTGAGAAAAATTTAGGCGAGAATTCAAATTTTCTGAGAAAAATTTGAGGCGAGAATTCAAATTTTCATAGAAAAAATTTTGGCGGGAATTCGAATATTCTGAACAAAAATTTGCCGGGAATTCAAAATTTCTGAAAATAAATTTAGAGAATTTACCTCAAATTTTCAGAGAAAAACGCATTGTGGCGGGAATTCAACTTTTCTGAAGTCAAAAATCTAGTCGAGAATTCAAATATTCTGAGAAAAATTTAGGCGAGAATTCAAATTTTCAGAGAAAAAATTTTGGCGGGAATTCAAATTTTCTAAGAAAAATTTTGGCGGGAATTCACATTTTCTGAGTAAAACTTGGTGGCGGGACTTCAAAATTGTATTTCTGAGAAAAATTTAGGCGAGAATTCAAATTTCCAGAGAAAAAATGTTTAGCGGGAATTCAAATATTCTAAAAAAAAATTTGCCGGTAATTGAAAATTTCTGAAAATAAATTTAGGCGAGAATTCAAATATTCAGAGAACAATTTTGGCGGGAATTCAGATTTTCTAAGAAAAATTTTGTCGGGAATTCAAATCTTCTGAGTAAAACTCTCTGAATTCAAATTTTCTGAGAAAAAATTTAGGCGATCAACTTTCAGAGAAAAATTTTTGCGAGAATTCAAATTTTCAGAGAAAATGCGAAATTTGGACGCGAATTCTAATTTTCTGAAAGGAAAAAAACTTCGGCGGGAATTCACATTTTCAGAAAAAAAATTTTGGCGGGAATCCAAATTTTCTGAAAAAAAATTGGCCGGGAATTCAAAATATTCGAAAAACATTTTCGGCGAGACTTCAGGGGTTCTCATAACGAATTCAAATTTTCTGCAACAAATTTTGGCGGGAGTTCAAACTTTCTGAGAAAAAATTTGCCGGGAAAAATTTCCGAAAGTAAAGTTTGGCGGGAATTCAAATTTTCTGCAAAAGATTTTGGCGGGAATGCAAATTTTCTGCAAAAAATTTTGTCGGGAATTCAAATTTTCTGAGAAGAATTTTGGTGGGAATTCAAATTTTCTGAGACAAATTTTGGCGGGAATTCAAATTTTCTGAGAAAAATTTAGGCGAGAATTCAAATTTTCACAGAAAAATTTTGGCGGGAATTCAAATATTCTGAAAAACAATTTAGGCGAGAATTCAAATTTTCTGAGTAAAATTTAGGCGAGAAAATTTCGAATTTTCAGAGAAAAAATTTTGGCGGGAATTCAAATATTCTGAAAAAAAATTTTGGCGAGAATTCAAATTTTCAGAGAAAAATTCTGGCGGGAATTCTTTCTAACAAAAGTTTTGGCGGGAATTAAATCAAATTTTCTGAGTAAAACTTTGACGGGGCAAATTCAAATTTTCTGAGGAAAATTTAGGCCAGAATTCAAATTTTCAGAGAAAATATATTGGCGGGAAAAAATCATTCTGAAAAAAAATTTGCCGGGAATTCAAAATGTCTGAAAATAAATTTAGGCGAGAATTCAAATTTTCAGATAATGGAAATCGGTCGAATTCAAATTTTCTAAGAAAAATTTTGGCGGGAATTCACATTTTCTGAGAAAAATTGTGTTGGCGGTAATTCAAAATTTCTGAGAAAAATTTAGGCGAGGAATTCAAAATTTCTGATAAAAATTTTGGCGGGAATTCAAAATTTCTGAAAATAATGGCGGGAATCCAAATTTTCTGCAAAAAATTTTGGCGGAATTCAAAATTTCTGAAAATTTGCCGTGAATTCAAAATTTATGAAAATAAATTTTGGCGGGAATTATTTTCTGCAAAAAATTTTGCCGGGAATTCAAATTTTCTGCAAAAAATTTTGGCGTGAATTCAAATTTTCTGAGAAAAATTTTGGCGGGAATTCAAATTTTCTGGGAACTGTCAAATATTGGCGGGAATTCTAATTTTCTAAGAACATTTTGGGCGGATTCTAATAGCTTGAAGTCTGAGAACATTTTTGGCGGGAATTCATTTTCTGAGAAAAATTGTGGCGGGAATTCAAATTTTCTGAGAAAAAAGGCGAGAATTCAGATTTTCAGAGAAGCTCAAAAATTTTGGCGGGAATTCAAATTTTCTATAAACCAATTTTTTCAGAATTTCAGAAAACACCACCCATCAGAGCGCGTTTTCAAGGTCTCACTGTATTATTCACTAGGCTCCGAATTTACAACAGTGACACCTCCGAATTCAATTCCATCCATTATTTGACTTCCTATAAAAAGAAACGAGTCAACTGATATTCCTAGTATTGAGACGCTTCAACTCTTCTAGAAATTCGAAAAACGGGCGACGTAATAGTTGCCACGTATGTTTGGAGATGGCCGCCGAAACTGGAAAAAAAATCTCGTTTAAAATAAACTGACAAGTCTATATATTTTTTCTTTAAATTTTTTTATTCGAAAAGCACCCCTATTATATAAATTCTTTTTTAACCTACCATTTTTAATATTTGATAGCCGAGTCTTTGTTAGGCCATGTGCAAAAAGCCGGTCGGTACCGGTTTTTGGTGACCGAATTTTCAAATTTTCTAGGCCACGTAGAAAACCAGGTCTTCTTTTGACACATTGATTGTTTAATTTTCTCAATACAGGACCCTCTCCTATAAAATCACGGTTAATTATAGGCGATAAGACGCCTATGGCCGAGTTTTGTTTATCTCTAGGTCATGTAGCAAAAACTGGCGATACCCTTTTTAACCCCAGAATGTTCTCAAGAATCATATTTTTTAATTGTGGTAAAGGCCCAGAAAATTATGTCTGCTGAAATCACAAGTCGGCAGCCTTCTCGCTTGCCAGGTCGTCCACGCTGCAAAAACTCTGTTTACATATAGACCTTTTCAAATAATTTCAAATAAAAATTAATCACTTATAAAATCATTTACTTCAGGATTGAAAGCTTTTGCTGGTTAAAACCGGAAATAAGTCGATACGGCCGAGTATTCTCTTTTCTAGGCCACGTACCAAAAGTGTTCAGATTTTCCCCAGAAAGTTGTCAAAAATCGTATGATTTGTGGAAAAGCTCAGCGTAAAACTATGAAAAAATGAGTCAAATCGGTGGCCGAGTTTTCTCTTTTTAGGGCACGCTGCTTAAACTTCCATTTACATTTTGGCTTTTAGATTCAAATAAATATTATTCCCTCATAAAATCGTTTACTGTCATTGTGAGAGCGGTTGAAAACAAAAAAATGGTGGCCTTTTTTTCTAGGCTACATAGCGAAAAACTCACCTAGTATACACATGAGCAGCTAACGACACATTCTGCCATCTAACATTATTATAAATAGGCGGATTACATACCAAATCCTTCGGATTATTATCCGCCTGCAAATATCGAATTTTTGCGGTATGCCCATTAAGAAGCTCCGGCTCCGTGAGCTCTTCCTCAAGCACTATATTACCCACAAGTGTCACGTATTGGTAATACATAAATTATGCGGAGTTGCTCTGTGGATTTGAAGTGGTTCGAGTACGGTTTTTGTGTCGTCACTTCGGTTTGCGATAATTACGACGTTCCCAGCATCCCCAGGGGCGATAAAGGTTAGTGTTATTTGGTTTTTGTAGAGACTGAAAGAGTGGTTTCAACTTGAAAAGTAACGTAGTTTAAAACATATTCTTCTTTTTTTATTCTGAGATATTTTGATTCTGAAAAAACAAAATTTTTTTTAAATAAAATTGGCAACCTCACAAACTGTGAGTTTGTTGAAATTTAGTTTTTACAACCAATTAATTTTTTAAATTAAAAAAATTTTACGTGTAGTCCTCTAGAATAATTTTAAAAATATATGAATAAGTGTTGAATTCTGCCCAGTTGTTTTTTTTGCCGGTCGCCGAGTGGACTAAGTGCAAAAATTTGGAATTTTTCAAACGGCTTTATATTCAAATCATCAACAACTTAAAAAAATTTAGATTAAAAAATTTTTTTTGGAAGTTTTCGAAAAATTTTGGAAAAATTTTTAATTTGATGTCAGAAAAAAAAACCAGTTTGATTTTATTTTTCTTAAATTCTTTTTTGAAAATTTGTTGAAACTTTTTTTTAAATACTAGACTTTTTTTTTGAATTTTCACGCTGTTCTGGTTTCCCTATTTTGAGATAGAAGAGTTTGCCGAACTAGGCCATTTTGGCTCGGCCATATCTGGGGTAGATTTACGGCGCGTTGCTTGTCGCGTCGCGGCTCGATATTAGTTGAAAAACTAAATGTATTTGTCAGTCGGTACACGACTTTCCCACGCGTTAGGCGATTATCAATGGACGCGAAAATTTAATGCAATGAGGAAGGCCGGAACCCCGTGAAAAATACATTTTAAAAAATACATGAAAAATGTTCAAATTTTCTTTTTAATTCATAAAATTTGAAACTACGTTTTGTAACTTTACAAAAAGATAATTTTTCGAAATTTTTTTGAAATATTTTTTTTCGATTCTTTTTGTTGATTTCAATTCTCTTTTCTAAACATTCAATATTCCTTACCTGTATCCCTCTAGCCATAATAGTACGCAGAAACAAAAAATGTCTTCGTACGTTGTTATCCAATTCTTTAATCTAGTGTATGAATTTCGAACACGTCTTAATGCAGGCAAGGGATGTATTCAAATATCAGTACAAATGCTAATAATATTACGATATAGGGTCCTGCAACGAATTCTCAACTGCTGGTAGAGTACGGAATAGGGTTTGAATTGAAAATTCCTTCGTACAGTTTCGTGTCGGAATTCATTTTTATTATGGGAGGAAAACAATCTAGTGGTGGTAGTGGTAATGTCAATCGCTAAATCGATGTTGAATAGCACACTTCCGATAAGTATCGGGCGCCAGCGTGGCCTAGGATTTGGGAAAATTCTTCCACCAGAAGGTAGTCCCAGGCTTTTAAATATGATTATTTCATCAAGAAATTTACAACTAAATTGAAAATCAACAGTTAATACATTTTTTCATAGACTTTTCGAAACATATCTGATTTTTACATATCAAATAACCCGGTACGCATCTAACCGTCAGTTGCCTCGTGGCCTAGAACGTTTGCAAACTCTTTCACGAGAAGACATTTCACCGTAGCCTAGTTACTAAAGCTTTGAAACTTCTTGCGTGCAGTTCGCTTGGAATTTTTGCTTGTTTTGTCAACTAACTAGGATTCAATAGCTATTAAAAAGTTTCAAAATTGGGCAATTTATGTAAAAATTCACAATTTTGAAACTTCTCGAAAACTAGACGATTAATTTTGGTAGTGGACTCAAAATTGATCTTCAAACACTAAAAAATAGCACTTTTGTAGAATATATTCCCATAAGATTTTTTGCAAAATTATTTTTTTTTACCCAAAAAAAAGGACAGTCATGGCTGAAATAAACTTTGGAAAAAATAAAAAAATTGTCTAAATTTGCTGAGGGTAATTCATGCATTCTGAAAAAATCTGGGTTTAACCCATCAAACAACATTAAAAGCGGCATGGGTATTTCATTGTAAAAATAATGCATATACAATAAACAATGTAGAGGTAGGTGCAAAATCTGTAGTTTCTTTGAAAGATTTTTTATTTATTTTTTTGTTATTTTTTTTGCAAATTTTCGTATATTTAAGTAGTTAGTTTGCATGTTACATGCTAATGAAAAGTTTGCATCTGCTGATACATATAAAAAAGCGCCGAGAAATTCACAATTTCAGTAAACCATCAGTAAGGTATTTAATTTTTGTAAACTTTAGTCTTCTGCTCCTCTAAAGCTTCTGGAAGAGGACACTTTCTATATCTTCAAAATATTTTTGTGCGCCACTTTCCTGTCAAATTTCTGGCATTATTACATCCAAAAAGTCCCCATAAAAATCGGAATTCCATGGCTACGACAACGTCAGCAAAAGCGGAAAGAAATTTTATATGCCAGTCTAACGAGTCACAAAGCATACACTGACGTTTCTATCAGAAAAGACAGGATATCGTATCAAAACAAAAATTGGGTGCGATTGCTCGATGCACCATGTGATATTTTGCTTTTTTTAAAAATTATTTTGCTCGTTAGTATGGTGCACTTATTCCGTGGGAATGCACGCGGTGTCATAATGCCCATTTCGTTGATGTGCGTAGATCTACGGCAAAAAAAAGATTGCGGGAGTTGAGACGCAGAGGTAGGGCTCAATTCGTGTGGTTAAGAGCGTGCTGACGTCACATTATGGGCAAAAAATTCCCGCATTTTTTATAGATCGAATAAACCGAAATGGCACATCCTGACACCATGTGAATGCAAAAGACTTTACGCGGAACTTTTTAGATTTTGTTACTAATAATCTTAGGATTACCAGTGCTATGGTTTTATAGAAAAATATCAAAAGCGTTCAAAAAGAAATCAAAACATTTTTTCAAAATTTTAGATTTCCACTTTCTATTTCAACTTTAAAAGACTTATTCAAATTTTGTTTTGTTGATTCAACGATTTTTCCGCATTGATCTCACCAAAAGAATTCATCACATCATTCAAAACTAAAAACTCACTTGGCTTTCATTCCGCTCAGATGACAAACTTTTTGGTGGCAAAGGTTCTTTGGGGGCATAGTATCCAAGGAGACAAGCATAAGTATCCAGTAGACAAACTGGGGTGTATCTTGGGGGGCATGTATCTTTGGTGACAACCTTTTTTTCCGACTAGATTTTTATATGTACCTTTTTCAACTACTTTTCTATGTTCACATTTTTCTGAATAAGTTTTTTAATGCAATTTTCAATCGATTATCGGTGATAATTCCCTCACCATTGAATGTATGAACGATGGATTCTTTTGGGAAAAGCTCTAGAACGTCCAACTAACTTGGAATGATCGTGCTAAGTCTTCCCGATGGTCTGATCCTTCAGCTCCGAAGGATCAGATGTGTCCCTTCATGTTCTGATCCTTCAGACATAAGTAGGATCGTAAGGGTACCTCCTGATGGTCTGAACCTTCAGATCTCGGCCAAAGGATCACGGGGCTCTTCCTGATGTTCTGTCAGCTAGGATCACATGGGCACCTTCAGATGATCTGATCCTTCCTGCAGATAAGAAGGATCGTAAGGGTGAACCACTTGATGGTCTGATCCAGCTCCAAAGTTTGAGATCACGACGCCCTTCCTGATGTTCGATGATTTCATCTTCGACAGATCATATGGATTTTTGACAAAATTTGAAAAAAAATTTTGAAAAAAAACTCGAAATTTTTTTTTGTTATTCTCCCTCTGCCATTCTTTAAAGAATAGTGCAAATTTATCATGATAGGACCGAATAACTTTCAAGAAACAGTATAACTATACATGATAATCACGCTTCTACCAAATAATGATAAATTCTCCGCGATGACAAACTTTTCGGTGACAAAGTTTGGTGGAGAAACAAAAATTACCGATACTAAACTGGTAGGTAAGGAGAATAGTGAAATAATAGAGTCCTACAATGGACTATTAAACATGTTCAGTAGGTCAGGACTCGTCCGTCAAAATAAAAAATTTGTCAAACGAAGTTCGAAACTGGGCCCTGTAGGATGGAACAAAGGGCGCTCACTACCACTACACCAACTATGCGAAAGTCGAGCCTCATCGAAGGCTATTATAAAACATAGTTCGAACGAGTATGATCGACATTCCACAAACAGTAATATCTCTCAACAAGAATCTCTTCAGGGAATTGAGGTCATTTCCAGTGACTATTAATTTATCGGTTTTTTCTCAAGTTGAGCATAGGGTCTTTTAATTTTTTGAACATAGAAAATCACGAAAGCTGCCTGTGCCCTGTATCCATCACTGGATCGAAATAGACGTAGCTCTGGCCTAAAATATTTCCTGAACAGTGATCATTTCATGTCCATTGTGTGTTTCTCTGTATTTTGCACCAGAAAGTTGAACAAAAATGATAATATTATATCGAATAATGGAACAAATACAAATAATTCTGACTAATCAAATTTCCTCCGGATATTGTTTTTTCTGTCATGATTATAAGTTTCTAAGTTTTTTATAATGTGTTTACAACGTCATAATTACCTTCCTTTCAAGCAAAAACCGTTCGAGGCGTCTTAAAAATAGATGTGCAAAAAACTTAATTCGTTTCGATGAACACCATACTACGGTCGGTGTGACTTGGCGTGGCGGTTTGCTTTTGAATCATACTATTTGACCCACCAAACTAAATTAGCAATGAAATTATTTACTGCAAATTCTGCATCGAAAAGGACATTACGATGGAAAAAATGACGATTTTAATTATAAAGCAACACATTATAAAAAATTTAAGAACATATAATCATGACAAAAAAAACAATGTCCGGAAAAAATTTGATTAGGCCTAAAATAAGGTTATTTACTCCTTTTTTTCCAATGTTTATCGATTCAATATCAACATTTTTGTTCGACTTTCTAGCTCAAAATTCATAGAAACTCACGATGAACATGAAATGATCACTCAGGAAATTACTTTAGGCCAGATACGTCTGTTTCGATCCAGGATACAAGGAACAGGCAGCATTCATGATTTTCTATGATCAAAAAATTCACAAAACACCCTATGCTCAACTTGAAAAACCGATGTCGTAAAAATAGTCAAATGACCTCAATTCCATTAAGATATTCTTGTTGATAGATATTACTGTTTGTTGAATGTCGATCATACTCGGGCGAACTAAGTTTTATAATAGCCTTCGAGGAGGCTCGCCACTTTCGCATAGCTGGTGTAGTGGTAGCTCTGAGCACACTGGTTTGCATCCTACCGGACACCAGGTTCGATCTTCGTCTGACAAACTTTTTTTTATTTTGACGGAAATCAGTAAAACACCTACTGATGTTTAATAGTCCATAGGACTACTCTATTTCACTATTCCTTTACAGTTTTCGGTAATTTTTGTTTGTCCACCAAGATACTTTGTCACCGAAATGTTTGTCATCGGCGAATTTATCATTATTTGCTAGAAGCTGATGATCATGTATAGTTATACTGTTTCTTGAAAGTTTTCGGTCCTATCATGATAAATTTGAACTATTCTTTATAGAATGAAAAAAACAAAAAAAAATTTCGAGTTCTTTTTCAAAACTTTTTTCTTTCAAATTTCGGTTGTCAAAAATCCTTATGATTCCGTCGAAGCTGCGAAGGATCAGAACATCGTAGAGGAGGTACCCTGATCATTCGGTTATCTCTGAGACAAAGAGATCATCAGGCAGAGCCTCCTGTTCTTTTGGAGCTGAAGGACACAACATCACGAAGAGCCTCATGATCCTTCTGAAGTAACAGACCATCAGGAGGTACCCTACGATCCTTCTTATCTGAAAGATCAGATGTCCCCATCAGAAGGTACCATGTGATGCTTCGGATCGGAAGGATCAGATAGGACATCAGGCAGAGCCTCATGTGCTTTTGGAGCTGAAGGAGAACATCAGAGCCTCGTGATCCTTTGGAGCTAAAGGATCACACCATCGGGAAATCAGGTACCCTTACGATCCTTCTTATCTGAAGCATCAGAACATCAAAAGCCATGTAATCCTTCGGAGCTGAAGGATCGACAGACCATCAGGACGAGCCTAAACATGGTATTCCAAGTTAGTTGGACGTTTTATCAGCTATTACCATCGTTCATACATTCAATTGTGAGGGTAACCGAAAATCGATTGAAAATTGCATTAAAAAGCTTATTCCAGAAAAATGTGAACAAAAATTAGCTGAAAAATACATATAAAAATCTAGTTGAAAAAAAGGTTGTCATCGCCAAAGATTATGCCAGATACCCCGTTTGTCTACTGGAGACTTTGTCTTGGATCCCCGCCAAAGAACCTTTGCCACCTAAAAGTTTGTCATCTCGAAAGAAAGCCCCCCGACTCTGCGCGTTATGGTGAGACCCTAATACGTCATGTTTGACCCGCAAAATATCTCGTAGCGAAAAATACAGTTATTTTTTAACCGTATACTGTAGCGCTGTTGTAGAAGTTTACGGGATCTCTATTTTTCTAATGATTAAAATTAACAACAAATCAGAAGAATGACCCTCACACGAAGAAACGAAGAGAATGAAATATCGATGTCACTTTTCGGAAAAAAAATTAATTTCAAATGAGCCCGTAAATTTACACATGCGCTACGGTAGACATTTAAACAATTACTGTAGTTTTCCGCTCCCAACGAGAAATTTTGCGCGTCAATAATAATATATCGCACAATAAGCATTCTCAGAATTTTGCATGTTCCCGGAATAATTTATTTAATGGTTTTTTTGGTTGTTTCCTATTGGTCCCAAAAATCAACAAAAAAAAATTTGTTATGAAAAATTTCTGTTTTCTTCCGTTTAAAATCAAAAGTTTTTTTAGTTGCTTTTTTTGATAAATTTTTGCAACCACCCTGATTTATATCCCGATAAATGTTTAATGTCCCGCTTATGATATCTGGAACTGCCTCTTTGCACGTAAAATTCCTACCTGCGGACCAAACACACCATACATCACGCGCACTTTTTTTTTTTTCATCTGGACAAACACATTTTCCGCATGATTTCACTGACTTTATTTAACTCTCATCACTCGTATCGTTAAAAAATGCCCTAATCATCAACCTATTTTCATTGTCATTCAAAAAAAAAAACTATTTCGTACTCGGCGATCGTACTAATTTGTCATCATTGCGTTCCGTCGAGCAAAAATCAATCGGGAGTACTTTTACGTTTTCCGTTGAAAAAAAATCCAAAAAAAACACCATCCAAAAAAGATCCAAAAAAATTCCTAGTTAATTAAAACCGGGAATAAAAAATTCAAATAAAAAGTTCAAACGTTTCGTTATAAAAATGTACACCGGTAAGCTGAAACATATACATTTCATAAAGATTCTAACAATGTGCGACGATACGCTCGCAGTTTGTAGTCCAGCTCCATTCAGTGATGATGTAGAGGTTATTAAACAACAGGCGATCGATTATCCCATACAAATCACTCTGGTAGCGATTTCTGGGAACGGTAAGCCGTGCGCTCCGTTGTACTCATAGTTCGATGAATGAAGGCATCCGTGTAAGTTCTCAAATTTTCAAATGAAAACTGCCAAAAAAGGTTTTTAGTTATAATCTAAGAAATTATCGATTTTTAAATTTTATGAAAATTTTTTCGAAAAATTTGGGTTTTTTGTTTTTGTTTTTGATTAATTGATTGTTCGGCAAAAATGTCAAAAATCGAAAATTTAGGTATTTTTTCTTGGGATGAAAAAAAAAAAACTTTATCCGCCCGGCTAAGCGAAACTTGTGCTTTTTCGGTTTATTGATTTAAACCTTTGATTTACTGGAAAAACTTGAAAAAATCAATACTTTTATCACTGCGATCTGGTCTTCCACTTTAAACCTCGCGCTCCATTGAGAATCGCGGACAACGCATCGCGGGAAAGCCGTGTACTCCACACGGACAAGAATACAATTAGATTTACAACTAAAGTGTGACGAGCCGCGACGCGACACAACGCGCCGGAAATCTACCCCAGATATGGTCTGGCCTAGATCGGAAAAAACTCTTCCATTTCAATTTTATTATGAGGGAAGCCAGAAATCTTTGTTTTTATTTTATGCGATTTTGCTCTAAATTATCGATTTTTTGGAAAAAGTTTGAAAATTCCATAATTTTTTAATGATTATTGGAACTAAAAATTAAAATTTTCACAATGCTCAAAAACAAAAATTACTGATGTTAGATAAAAAAAACACGGCATGCAATTTCTAGACCACCGAAACTATCAAAAACCTCTTCCAGTGACTCGTCCGGTCCGTCTCTACGCAGACGGTGTCTACGATATGTTCCGCTACGGCCACGCGAATCAATTCCTGCAGATCAAACAACCTCTTCCGAATGTCTACCTTATTGTTGGCGGTGAGTTCGGCCCGCGCAATTCAAAATTTTTAATTTAAAAAAAAAACGATTTTGTCCAGTATGGTCCGAAGAGTCTATGAAGAATAAGGGGAGAACTGCAGGGCAAAGGAGAGCGGTTCGAGGCGATTCGGCATATTGTGCCGGTACGTCGACGAGGTGTATCAATGAGGCGTCGCCGTGGATATCTCCGATACCGTTTTTTGAAGGAGGGAGGTAAATTGCGCGTGAGATTCGGTGTTCGCACAGTTTTATGTCCAAGAACGAAGGAAATTTTATACCTAAATTTCGGAGAAAAATCATCAGTATAAATTATTGCCTTTTTTAAACGTCACTCACAAAATCGATAATAAAAGTTTGAAAATCACAGTCAATTTTTATTTTCAAAATTTCGTTGTTCTATCACGGGAACGCAAATTTCTCAGCATGCGTACTACACAACACATTTGACGCGCAAAATATCTCGTAGCGAAAACTACAGTAATTTGTTTATTGACACTGTAGCGCGCTACTGTCGATTTACGGGCTCTATTTTAAGCTCTTTCTATCGATACATATAGGATACATATTGATCCCGTAAACAGACAGCGCGCTACAGTAGTCAATTAATGAGTCACTGTAGTGGTCTTTCACTGCTACAAGATATTTTGCAGCCTCAGACATGTTGCGCAATAGCATCCTCAGAATTTTCTGTACCCCGTAACAAAACTTCGAGTTTTTCGAAACAAAAAGTTTAATTTAAAAAACCTCTAATCTTCGAGATATTCGAGTATTGATCTATTGATTTTTCGATAAATATTTATTTTTTTTTTACGATATTCGAAACAATTATCGAAATTTCAGAACTAACAAAAAACATTTGCGGAGGAAAATCGATAACATTTTCAAAGTATATTTTGTGTCCATAAAATTGATTTTTCCGTAAATTTAATTTGTTTGATTTTCGGGTTGGGTTCGTATTCCTAATTTCGGTAATTTTGAGTCGATAATTTTTTGTTTTTTTTTTTCAATTGAAACTTTTATTGATCAAGTTTCTGGCCAGTGCTCTTATAAATTGAAATGAGAAGATTTGGCCGAACCAGACCATTCTGGCTCGGACATGTCTGGGGTAGAATTACGGCGCGCGCGTCGCGCCTCGATCCTTTTAGCTTGTAAAACTACATGTATTTGTCCGTGTGGAGTACACGACTTTGCGTTGTCGAGCAGGTGATTGTCAGATGGAGCGCGTACAATGCTATGAGGAAAGCCAGAACCCCGTGATTGATTAGTTTTTGACTTAAAAACCTGATTTGAAAGAAAATATCGGTAATTTTTCGGATTTTTAACAAGAAAGGTCTTTATTTCCGGAAACTTTCATTTGATAATTATTTATTTATTGGTTTCTCGGAAAAATTTGCCGAAATCTATCGATAGTCGGACAATTGGACGAAAAGTCGAAAAAAAAATTCTAGGCCACGAATTTCCTCTTCCAGGTTGACTTTATGTCACACGACGCTCTGCCATACCAAGGTACCGCCGGAGAAGACATCTACGAGAAGCACGGCACTGCTGGCATGTTCCAGGAGACGCAGAGAAGCGAAGGAATATCGGCGAGCGATTAGATTTGTCGAGATTATGTCAGCGACTACGACACGTATGTCAGAAGAAATTTGCAGGTGAGAGGATATTCGGCCACCGATTGGAACGTTGGCTTTTTTACAGTGAGCCTGGCCTAGAAAGGGGTGGCCTAGAAACAAGTGGTGGCCTAGCAAGACTCTTCCATTTTTTTCAGACCAGCAAATATAGTCTGCAAGACACCGTAGTGGTGAATAAAAGAATTGGGCCGTGGCCTGCTGCAAACGTGGAAAACGTTTTGAATTTATTGATTGAAAGAATCTTGACGACCATTTGCCATCGTGATCTTCAGCGAAACCGTTCGAACAACAAAAGGGCCGATGAAAATGTGGAAAATAGGGAGAATATTGAGTTTTTAAAGAAAATTCGAGTAAATTATGGGAAGAAAAATTATACTCGTGAAAGTTAACTGAATTTATGCAATTTATTTTTTGAAATTCTCAATTTTTTTGGAAAATTTTTTTTTCTTAGGGCTTAGTCGAACATTTGGCTTTGTTTTAGGATTAAGGCTCATGCTTAGGCTAAGGCTTAGACAAAAACTTAAGCTTAGGCTTAGGCTTTTGATTAGGCTTAGGATTCAGGAGTCGGTGTCTTTCACTTAGGTTTGGCGTCATTGGCGAGCGTTAGCTCGCTATTTAGGCTTGGGTTAATTAGGCTTAGGCTTAGGCCTAGATTTAAACTTTTAGGCTTAGGGTTAGAATCACGCTGGCTAGGGGAAAAAAGAGAAATTCCAAAAATTCCAGGTTAAACGTAAAAAGGACAAAAAGGTACATCCCGAAGTCGGGTCAAAAAATAAAGTGATGAAATGTTCGGGATACATGAATGAATATTTCTGAGTCTCGCGGATTTATTTTCATAATCATATTCTGAACGTATTATTGACTCGTCGTGTGGGACATTTCAATGGATTTTCCATAGAAATCTCTGTAGAATTCCGCCATCGGCCAACGATTCTTCACAAGAGCCAAACTCGGCGAGTCGGTCAATGTTTGAGCTCGTCTGAAGAGTTTCAAAATATATGAATTCATTTATCTTGCAAACCTTTCACCGTTTGTGTTCAGTAAAAAGTCCGTCGGGGCAGATTTCCGTATCATCAGACGATTTGCATGTATACAATCCACATGAGGTTTTGTTCGCCTTTAGAATTTCTCCCAGTTGCCTGGAACGTTAGTTTTTCTGAATTTTTTGAAAGGTATAGAGATAGCAACAAAAAAAAAAATATACCCAAATAATGAGCTATTTAATCTAGGGGCTTTATTACAAATACTTTTCTAAGAACGTCTTGGTCTTGATAAATGCGTGCTTTAAGAAAAAAAAAAGTCAAAAATAATAGCGAGTCCTCAGATGTCGGGCGTTGTACTTATTAAACTCGGGGTCAATAAGTTCCGGGTCAAAATTCATAACTTTTGCGTAGCAAATCGATTTCCTTAAATGTGGGACTTTATGTTATCAAACATGGTCTTTTATTTGACGGCACTTTCAAAAAGTTTTGCCCACTCCATGTACCCAAGCTCGGATCCACTTTTTTCAGGCGTATGCCCGATCTCGCATTTTCTTTGTAACTTTCAATTGAGACTTTTGTGCGGATTTTGATTAATTAAATATACAATGTAAGAATACAATAAAAATTTGAGAAAAAATTCGCTCAAAAAAACAATTTTTTTGATCGGCAAAAAACTTAACCCTCGAAAAAAATTTTGTCGCCCAAATCTCTAGGTTTTATGGAATGATGCAAACAATTCTGAACAATTATTTAACACATAAAAGTTTTTTGGATTTAAGGCGTCACACACAAGCGGCAATGGAAAAAATGATTTTTTAGTGAATTTTTTGAAATTTTTGAGAAATTCTCGTCTAAATATTAAATTCTCAAATGTTTTGTGTGTCGAAAAATTGTTCAGAATTTTGCATAATTAGTCTCCTGTACAAAAATCCAGAAATTCCGACAAAAATTTCTCCGAGGATGTTGACGAACCTAAAAAATTTGTTTTTTTGAAGGAATTTTTTCTCTTTATTGTATTCTTACATGTATACTTAATAATTCAAAATCCGCACATAAGTATCAATTTACAGTTTCAAATAAGCAAGATCGGGCATACGCCTGCATAAAAAAGGATCCGTGCTAGGGTACACGGATTGGTCAAAATTTTGAAAGTGCCGTCAAAGACCATGATAGATAACATAAATTCCCACGACTTTTAGAAAAATCGATCAGCCACCCGAAAAAAGTTATGAATTTTGACCATGGTATCGAACTTTTATCGTGTGCTACATGCTTGTCGCGAAATATACCTATTTACCTATACCTGTACCTATACCTGCTTCATCTTTCGATATACGCCGTTCAAATTGTGGAGCATCTTGTCCAAATCGTCGTATCCTCTTCCAACTCCCAGGTAGATTAGTTGTTGAATCTACAATTTTATATTTAATTATAAATTGTATATTTTTGTAATTTAAAAAAAAACCTTTCGAAATGCGGCTAAGTAATCAATAATATTGACCTTAATGCCATGGGTCCTCATGGAATTTTCTGCCCATGCACAGTGTAGGAGAGCTCTTCCACTCCGTTCCGATCGATCAGCACATTACTTAGATAAATTAAGTCCCTGTGCTCGAATTCAAGAGCTGCTTCAGCTGCAACCATTGAGAGACCACGAGCTGGTGAATGATGGAAAATAGTTCATCTTCACTTTCAAGGACAAAATCTGCCAGCGGGGAAAGATTCCACCATTTGCCGAGCCGGCTGAAAAGGATAAAGTTTTGATGTTCCTGAAGAATAAACATCTGGCCTCAAATGTTCGGATTCATTGAGCTTCTCGTAGGCATCCCAAGCTCTCAGTAATCCCTTAGGATTTTCCCCTATGACTATTTGGGCTGAAATCATTTCGATAAAATTCGGCATAGAATTCCAAGAATTTGGGTCTCGAGTATCACGCCGACAGTGATTTCCTTGCCCATCACAATCACCTCTGACAAAACGGCGTGGGTTGTTGGAATCTCCACGGATTGATTTCCATAGAAATGCACGTTGTTTTCGAATGGCAAAACCTTTGTTAGCAACCGGTCTACCATTCGGCGCCAGACAGCTGAGAAGACTTCACCGTAGGCTCCTTCGCCGAGCTTCCTTCACTTTTCGAGCATCTAGCGCCGACGTTGATAGGCTACCCCATGGTTTTGCTTCTTTTTGGGCCAACAACACGGCGAAGTTGTGCCATGGACGGATCTTTTTTGTGAAATGTGATACTGCCAATGGGGATATTTCTAGAATCAGGATGAGCTGACCGAGCACTTGGAGCTCATTTGTTCCAGTTCAGCAAGCATGCACAGTTCGAAAGGATGGACAGTCCGAAAATGACTTTTCTGAAATTGTCATAGTTCATTGTGAAAATTCGTTTCGGCTAAAAATGCAAATGCATTATGTTTCTGAAACTCACCAGTTGACTCTGAAATCGTCGTTCGTTGTCATGTCGAGTGCCAAGAACGGTGGTGGTCACCACTGCCGTCTTTGTGAACCGCATCCAAATCGACAAATGTCTCGGGAGTTAACTATAGAAATGAAGTTTTGAAAAATTAAAAAACTCACAATTATTGAAACACGTTATTAGGCCAATAACTTCACACGTGAATTAATACATTCATGTATTCGATTTTCTCTGACTGTTATCACGGGTTTCTGGCTCACGGTAGTTCAGCCACGGTCCCAGCACAGAAAATAGATGTCACGTTCATGACGAATAATCAGTCTGAAAGCTATATTGGCTGCTATCTCGAAAACTCTCTAAAAACGCGTTTTGAGAAATTATATTATGATTTTTTGGAGAAAATCAGAAATTATTGATTTTTTTGAAGGAGAAAATGGGAAATTTTTCATTTTTATTGGGGAAAATCAGAAATTATTGGTTTTTGGAGAAAATCAAAAATTACGATTGGTAATTTGAAGCAGGGGTGGGCAGCAATTGCCGTTCGGCAAATACGCAGATTACCGGCCGATTTTCCGGGTTTTCATTTACGGCAGTTTGCCGGTTTTGCGTTCAATTTGCCCGACATTTTTCAATTTCTCCGGCAATTTGCCGGTTTGGCGATTTGCCCGAATTTTTCAATTTAACCGGCAATTTGGCGGTTTGCCAATTGGCCCGACATTTTTCATTTTCGGCAATTTGCCGGTTTGCCGATTTGCCTTACCCGAAATTTTCAATTTCGTCAATTTGCCGGTAATCGGTGCCGATTTCCAAAAATTTTCATTTTCGGCAATTTGCCGGTTTGCCGATTTGCCGGAAATTTTCATTTTCGGCAATTTGCCGGTTTGCCGATTGCCCGAAATTTTTCGATTTCGGCAATTTGTCGGTTTGCCGATTTGCTACGGAATATTTCATTTTCGGCAATTTGCCGGTTTGGCGATTTGCCCGACGTTTTTCAATTTCGGCAATTTGCCGGCGTTTTCCGATAATTTGTCGAAATTTTTCATTTTCGGCAGTTTGCCGGTTTGCAGATCTGCCCATTTAAGTTCGGAACTCAGATTGGCGGTTTGCCGATTAGCCCGAAATTATTTAAACGGCAATTTGCCGGTTCGCTTTAGCCAGAAATTTTTCAATTTCAGCAATTACAATAGAGGTCGATTTACCATTCAGCTGCCGGAAGTCTTCAGAAGGAATTTTTTATAATAAGGAACCACTAAACACAGCGTTTTGAAACTTTTCCACGTTTTTTAAAGATGATTTCATAGAATTTGCTTACTTGGTTTGTCGAATTGCCAGAAGTTTTTCAATTACAAGTTGGCAATTTCCGGAATTTTTAATTATGGCAATTTGACGGTTTGCCGAATTATTTGCCAGAAATTTTTCAAATTCGCCAAATTGCCGGTTTTCCGATGGAACTTTTTCTCGGCAATTTGTCGATTTGCCGGAGTCTTAAATTTTTCCAATCAATTTGCCGATTTGCCGGAAAAAAAATTGTTTCCCGCCCACCCATCAGTTGATGAATTCATCGTTCTTTTGTGTGTTTGTACTCCCATCAATCTTAAACTCGACCCGGACTGCAAAGGCATATTTACAGTTTTCTCTTCTGGTAGTGAAATGGTGGTCTTAAGTTTCGAAGACTATGCCCACGTAATTTCTAAAGTATTTATGTTTTGCAATTGTTTATCAATGACCCTAAAAAACAGACAAAGCATTTCCGCGTGGCAAATTATCAAGTAACTTGCCTAGGCGAATAGTACTGATGTTATAATTTTTTTTTAGAATCAGTTTGGAATTTCGAATTTTTCTGAAACAACCGCCGGCAAAATGAATTACTGTGAGCACTTTTGATTGTTCCCCGGTTTTCTTGTAGATTTTTGTGCAAAAAATTTCGACTTTCAGCGGTAAAAAAAATACAAAAAGGTCGAAGAAGAAGGAAACGAGCAACACTGCTTCTTGGTCAGGAGGCCCCAAAACCAGGGGGAGCAAAACAAAAAACCAAAACCATCGAAAGGAAATGCGACAGGGGTCGCGGCGAACCGGAATTGACTGCACATCGAAAAAAACCAAGACAGCAAAAAAAGTGAGACAGAAGAGAGATATAAATGCACCGGAGTTCAATTTTAAGCTCGTATTATAGATATACGTCATTGTATCAGGGGTGGGCGGCAATTGCGTCGTTCGGCAAATTGACCGCCAAATTCGGCATATCAATTGCCGGTTTGTCGATTTGCCGGAAATTTTCAATTCCGGCAATTTGCTGGTTTGCCGATTTGCCGGAAGTTTTAGGGTCATGTTTTTCGGTCAAATCAGTTTTGCCGGAAATTTGGTTATATAAGAGACGGACTGTCTTTTTGAGTTGTTCCCGTTTTTTTACATATTTTCATAGAAATTCATCGAGATAATTTGCCGAAATTTTTCGGCAAATTGCCGTTTTGGCAATTTACCGATTTGCCGGAAATTTCCATTCCGACAATTTGATATGCCAATTCGCCGGAAAAAATCGTTTGCCGCCCACCCCTGAATATAGAGCCCTTTTTAGTCTCATGTCACCTCGATCACGTGAAATGCTGTCAGACAGCAAAAAGACGACCGTTGATGATGATTCAGCAGTTCCAAGAACAACAAATGTCGCTGGAGCAGTCACTTCTACGATTCCTGCTCTCACCTCTGAAAACGTCCCGTTCTAATTCAGCCACCCAAAGACCTTATATGGTGCGGGACGAAAGCCAAAACGGTGCTCCGGAACTTGACGGATCTGGCAGCGTTTCACTTTCACTCAAGAGCTCACTGACTGGAGGTGATAAGTGGCTTGGAGAAGCCGTGGCAAGGAATTGGATTCGCTCGGTTAGCATCCTTTTTTTATTGGAGCGGCGGCGTAAAAATCGTGCCAGAGTTGCGAGAGGGGGCGTGTTTTTTAGTTTTTCTGTTGTTGGTGGGGACTTATTATTATTAGGTTGGTGATTTTATTTTCACTGGTGGAAATCAGCTAATAAAACTAAAAAATAACTTCGGGATATGCAAATAAAAACCCAACTTTAAAAAGCGAACTCCGATCAGCAGTTTGCTCGGCCCACTATTCAACCAATCCAATTGGTTCGTTGAAATTCTTGGGAACTCATTGTTAGAGGATAGAATTCAAACGAAAGATTAGCAAGTTCACTGGTTATTGCTTTCATTAGAATATCATTGCTTATATATATATTTCAATAAAAAAATAGTGTACGTCATCAATGGGCGGAGCCTCTTCCATCGTGGAGACCCATCGTGGTGAGACACGTGGTGGTGAGACCCATCGTGGTGAGACTTCGTGGTGAGACGTGGTGGATTCAGACCCGTAAATAGAGACCTGCGCATCGAGGTGAGACCCCTCCTGGTGAGACCCATCGTGGTGAGACCCATCGAGGAGAGACCCTTCGTGGTGAGACCCATCGTGGTGAGTCCCCCATTAATTTTGGCGTGAAATTCAAATTTTCTAAGATCGATTTGGCTTTTTTTCGTTTAACGAAAAATCTGGAAAGGAAATTCTAGCATTTTTTTAGAATAATCTGATGAGGAAATTTCTTACTTTCCAGCGAAATCTGGAAACTCCAAGGATTTCCTAACATAATCTGGAGACTTCTAAATAAGATCAGGAAATTTCTAGAACTTTTTTATAATCGTCTGAAAACATCTTTCTAGAGTATACTAAAAACTTCTAGAATTTTAAAATTCCGCGAAGATCGAGGAAGAGATTTGCCAAGTTCAATTAATGTGGAGCCAGACGGAGCACGCGCTTTGCGCGCGCGAAACGGCTGGTTTTAGATATTTTGTAGTATTTTTCAAATCTTAAAAGAGCAGAGGTGAAAAAAAAACGAACTGCAATAACAGAAAATCGATGTCGAGAAGGACTGTAAAACCTGGAAATCCAACTCGCGCCAAAATTTAACCAATCGGAAGACTTTCCTGCCTTGGACTTCAATCTCGTGAAACTTGGCAAAGACTAGGTGAACATCAGTCTTTTGCGTAGATGTTCCATTGGGAAGAAATGTTCATCTAGGTCAAGCTCCGGTCACACGGAAGATACATTAATGTTCGACAAGCGAATCACTCACATTGATCTACTCGGCGGGCCTGCGATGAAACCATCGAATTCTTCCCTATAAAAAAGGCAGAAGATTATACAGAATTCCGTATGGTCAGATGTGGATCAATCCCTTAACCGCCGTGTCGAGTATGTCAATGACGATGTGTACCGATTTGCAATTGAAGGAGTGCCCCACGGATTCTCCAACTCGATCAACTGCAATGTGACTGTTATCAGCATTTGGAAGGACGCTGTGCCTTTGAAACAAGCAATCGCCTCAGAGAGGCACTTGGTCTACACTACTTCTTGCTTCTGAAAGCACCCCCTGACGAATGCGACCGATGATCGTCTCACCACGTGGAGCTTGTAGGACGAGCTGGCTACTTTTTGGCACTTGCGGTTGCAGTCAACACGATTGATGCAAAGCTGGCCGAACCTGTATTGCGGATATTGTCCAATCGATTAGCTCCCAGAGACCAAGAGCCGTGGATTCTTGTCAGTATCTGCTCCCTGTGCATTTCGTTGCTCTACTTCATCAAGGAATTGGTTTTTGAGTTCTTGTAAAATGAGAGAATAATTCTCTAATTTACAGAAGAAAGGGACAAAACAATCAGAAGGGGAAGCCAACACTGAGCAACAAATACGTCTACAACAAGTCGGTTGAGTTGACGAAGCAATTAACCGTTCTCCTTCTAGAAGCCAGGAGAGTGTGATGGGACCTGGATAGTTCTTCTCCATTATGAATATGTGAAAAGCATTTGAATTGATCTGGGTTTGGAAATGAAGAATTTTATAATGGATTCTTTCCGAAATCTTCCTTCCTGCCTGCTGTTAACTCTGCGGCTTGATCTGCAAAAAAAGCGGTAATATCTCCCCCAGGAAGACGTCAGCACACTCTTAACCATGCCTTAGTTGAAACGTTTCTCGGTATTCTCCCGCATTTTTCGAAGATCACACCAAAATGGGATACTTTGACAACACGTGCCTGCCATCGCTTCCTGAACGGGGATTTTGTTAGAAAATTCGTGGAAAATAGGAAGAATCATTTCGAGAAAATGGAATTATTGACTCTTTTCTGATTTTCTCAAACAAAAAAAAATTAAAATCGAATTGATTTCTGGCTTACCTTACCTAAATAGAATTGAAATGGAAGAGTTTGCCGAACTAGGCCATTTGTGGCGGCCTGGGGTATATTTGCGGCGAGTTGCGTGTCGTCGCGGCTCGTTGTTGTAAATCTAAATGTGATTCGACCGTGTGGAGTACACGACTTTCACATTCGTTGTGCCGCGGGCGATTGTCAAAGGAGCGCGAAAAATACAATGAGGAAATCGGCCAAAACCCCGTGTATTGATTTTTCGAAAATTTCGGAAAAATCTGCTAATTTTATTCAATATTTACATTTGTCCTAATTTCTTAGAAATGTTCAAAAAATCTGATTTTCTTTTTCCCGATGAATTTTTGTAAAATAGTTGCTATCCGTATTTCTCGAAAAGAATCGATTATTTTTTTCCGGTTTCCTGGTAAGCTAATCACTTCAGAAAAAAGAATTAAGTTAATATATACTTATAAAAGTCGTAAAAGGTTGGAAATATAAAGTATTTAAATCAGAACAGCGATTACTGACTGAAGCATCTCAACTACCAGGCAAGTTCTTCTTATCGAACTCGACAAATGAAACGAAGAGGTCGGAGCTATAATTGTGCCGATCATTTTCCGGGCGCCCGTCTCTTCGAACTCGGATACGGTAGCCTGCCCGACGTATGTGAAATCGGCCATTAGCACTCAATCGGCAAGCGCCGATTGATGCTCCGTGGCCGACGATAGGGCTTCCTGAAAGAAAATCGATAATTTGCGGTGTGTTTTTATTGATTTTTATGTGAAAATTGGCAAATTATTGATTTTTCGGCTAAATCATAAATTACTGATGTTCTAACCCGTTAAAATCAGTAATTTATTGATTTCTTCGGCTAAATCAGGAATTATCGATTTTTCAGTGAAAATCTGAAAATGATTGAACATTTTACAGCTCTGCGAAAATCAGAAATTAGTTTCGCAAAAATTCACCTTCATATTTCTAAATCGCCACGCAGGGTCTTTCCGACACGTGGCACACACGCGTCATCTCCACATCCTTCGCGGGGTAGTGTGTTCTGAAAAAAAAGCCATTCGGTAATTTTTATAGGTCTCGCACCGGATTGCCGCCACCGGTTATCTTCATTTTTCCAACTAAAGCGCCAACACCGGCGCCGGCATCTTCTTATTTTTCCACGTAGCCGGCGCCAGCCGCGCCAAAACTATCTTCAAGCGGCGCCGGGCAGCTTTTTATTTTCCCCATAGCGTGCCAGCGGCGCCGCCGGCATCTTTTTATTTTTCCACGTAGCACGTCGGCGCCGGCAGCCGCGCAAACTATTTTCGCCGCCGCCGGTTTACTTTTCCACGTAGCGCGCCAGCGGCGCCGCCGGCAAGTTTTAATTTTCTTCCACGTAGCGCATAGGCTAGCGCCGCCCCCGGCATCTTTTCATTTTTCCACGTAGCGCGCCAGCGCCGGCAGCCTCGCAAACTATTTCACTGTTCGCCCGCCGGCATCTTTTTATTTTCCACATAGCGTGCCAGCGGCGCCGCCAGCATATTTTTATTTTTCCACGTAGCGCGCTAGCGCCGGCGCCGGAATTCATTCTTTTTTCCACATAGCGTGCCAGCGGCGCCGCCGGCATCTTTTTATTTTTCCACCTAGGGCGCTAGTGCCGGCCGCATTTTCATCTTTTCATGCAGTGACCGCCAGCGCGGCCGCCGGCCTCTTCTCATTATCCATGTCGCGCTAGCGCCGGCGGCAGCGCAAACGATTCTTCGCCGCCCCCGGCGCGTTTTCCTTTATTAATTAGTGCGCCAGCGCCGCCGCCGGCATCTTTTGATTTTTCCGCAGTGCGCCAGCGCGGCAACGGCGCAATTCTAATCTCGGTCTTTTTTGACCGATACCTGAAAACGCCTAGGAATATAGTGGGGCCAAATCTACAAGCGGAAATTTCTCAGCTAGTTTGTCGGTTTCCCAGATTCCAGGAGGCTTATCACAAAGATAAAGTGCCTCACAAAGGCCACCGTCCGCCTTCACTTTCATTCCTCTATCCTCAATAATCGTCGAAGCTGTCTCAATTGTCCGTCGAACGGCGAGGCAAACGTATGCGAGATTGCCATTTTCGAACCCATATTTTGCACTCTTTCGCCTGTTGCCGACCGCGCACGCTGAGCATCGAATTATCCGTCGTGAGACCGTCGGCTCCGTCGAGTAAATTACGCCAATTTCGATTGATATTGTTGTCTCCTCGCTGCAACGCAAAAAATCAATAATTTCTGATTTCCAACGTAAAATCAATAAGTGTTCTGATTTTTGTTGAAAAATCATTACTACCGATTTTAACTGAAAAATCAATAAATGCTGATTTTCCTTTTTTTTGCACGTACAAAAGTCGATAATTTCCAGATTCTCATCGAAAAATCAATAATTTGTGATTTTCGCCAACAAAAAATCAATAATTCAGATTTTTACCGAAAACACAAATTGATAATTTCAGATTTTCACCGAAAAATCAGAAATTATTGACTTTGGATAAAAATCAAAAATTTACTGATTTTCATCTAAAAATCAATAATTTCAACCATTCGCAGAAACATCGGTCATTTTTAATTTTCACCGTAGAATCAATAATTTCTGATTTTCACCAAAAATTATCAAATAATTTTAATTTTTTTTTCGAAAAATCAATATTTTCTAAGTGCTTTTTATCGGAAAATCAATAATTTCCGATTTTCACCAAAAAATCAATAATTTCAGATTTTTTTCGCATAAAAAAGCTCTGTAAATAATTTACGAAGTTGACGAGAAATCAATAATTTGCTGATTTTATTCTCACAGAAAATCAATAAATTTTTTTTGTTTTTCGTTGTTTTTTTTTTCTAAAAATCAGCGTTTTTAATTTCCCCAAAAAATCAGTAATTTTTTAGGGATTTTATTTTTCGAAAAATCATTTCAGATACCGAAAAAATCAATAAATTCAAAAAAAAGTATTTCATTTTTTTGAATTCTTCAAAGTACCGTTCCACGTGTCAGAACAATCCAAATTTTCCGTGGATAAGTTATCGGCATCCTATCGATATCGGTTTTAGCTGAAGAAAAAACTTAAACAATTGGAAAATTGTGTCCTCCTGTCGGACAGGTGCTCGGTGCTCTCCCATCACGGCTTGTCTACAAAAAATGCGGGATTCTTCGTTCTTAACCATACGAAATCAGTTGACTCTGCGTCTCTCTTCCCGCATTTTTTGTAGATCAACGTAGATCAGACCAAAATGAGGAGCACACTGAATGAAGACACCATGATTTTTCGAAACAAAAGAAATTCTCAAAAAGTGACGTCAAGAGGTATATAGGTAAATCGGATACTTGGTATCAAATGACGGAAAAACAAACGAAAGTTGCAAAATTTTTAGATGAAATTAATTAGACTTTGGCGGGAAAAACAGATCAAATTTACATTAAAATACCGGAAAAATAGGGGGAAAAAAGCCTAATTATTGCCTAAAAAATTCAGGATTAAACGGGTTGTACTTTTTCTTCTTTCCACGCTTCTCCTCCGATTCCTCGGCGGCTTTTCGTTTCTGCAGCAGCTCAATTTCCTCGGGATGTAGCAAAGCATGGGCTCTCGCTTTCTCGACTCGTTCCCGGCAGTTTCTAGACGCTTCTCGCATGCTCGCCAGGCCGTCGTTCTCGATCGTATACCTCTTCGAGTTGACGTTCTTCAGAGCTATCACGGTGGCGGTACTGCTTTTTTGGAAGAAAAATTGGGGGGTTTTTTTGTGGTTTGTAGTGGGCACCCTATATGCGCGAAAAAAGAGTCGAATTTTTTTGTAGATCAACGTATGGTGAAGAACGTACTGGCGTCATATAATTTTGGGCGAAATTCCCGCATTTTTGGTAGATCAAACCGTAGTTGAAAATTTTTCGGGAAAAAAAATTACGAATTTCTGGCTTTTCTCAAATTGAAATGGAAGAGTTTTTTCCGAAATTGGCCATTTTGGCTCGGCCATATCTGAGCTAGATTTACGACACGTTGCGTGTCGCTTCGCGGCTCGATTTTAGTTGTAAAACTAAATGTGATGTCCGTGTGGAGTACACGACTTTCCCACGCGTTGTCCAGGCGATTGTCAATGGAGGGCGAAAAATTCAATGAGGAAGGCCTGAACCCCGTGGTAGTCCGATGCACAAAACTGATTTTGTTTTTGAATTCTTGGGATTGAAGAAATTTTGCCGATAAAGCCGATAACTCAAAAAATTCTAAAAAATTTGGATAATGTCTGGAGGAAAAACCCCAATGCTGAAAATTTCGAATAATTTAAAATTTTTGCGCATGGCCGAAAAGAATAAAACTCGGCCAATTCTTTGGCGGCCATGATGCAAGACACCATATTTGACGCACGCAAAAAAAGGTGTTTTTGGATGTTATTTTCTTTTTCCGCCAGAATCTTTAATAATGGTATCTATTCCAGTGACAAAAAATCATAACCTGTTGCAAAAAACGGATGTTATTTTTTTCGAAAAATTCAATTTTGCGCGTCAGATGTGATGCTTTAAGCTCTGTGGCCGCCCAAAAAGAGAACACTCGGCCCACCAATTTTTCGATGACTCCATTGACAATAGCCTGCTGGACACCGGGTGGAAAAGTTTCGTGTACTCCCATGGGGCACGGACAAATACATTTAGTTACCATTTACAACTAAACGAGCCGCGACGCGACACGCAACGCGCCGTAAATCTACCGTGGCCAGATGTGGTATGGCCTGGCCTAGTTCGGCAGGAAGGTTTCTCTTCCATTTCAATTTATGAGGGAGGCCAGAAATCCGTGGCCGAAAAAGAGAAAACTCGGTCTCCATCCGATTTTTTTTTCTGACGGCCATGACAAGTTTGCGCGACAATAATACACTTCATCATATTTGGCAAAAAATTTTTTAAAGTTTTTTCGAATTTTTTTGATTTCCGAGCAGAAAAAAAAATTGTCTGAGAAATTTATGTGGCCGCGGTAAACTTCGGCCACCGATTTTCGAAGATTTTGACCGTGTTTGAGGGAAAAAGCAATTTGACGCGCAAATTTTCAAAAAAAAAAAAGCCCAAAACACTTTTCTTCTTCTTCTTGTCTTTTGTTAGATGCCGTTTCTGCCTTTTCTTCACTATCACTATCCTCTCGTTTCCGCCTTCCCCTCCTCTTCCAGCTTCCGCTCCGCTCAAACACGGCAGAGCATCGCGCGCTTTTCGTCGATCAAGTGTCGGCGGCTTTACGCAGCGGAGCTCCTCGTACCACTCGTTTTTGTTGTTTAAATCGTATTATCCGCGAAATACACCTGAATTCACATTTACGTCGACTCCCATTCCTTCTTCTCGGCCGCTTTTTCCGCTTCGTAGCCGCGGTTTCCGGATCCATAGTTTTTTCGTTCTTCACGTTCGAGATCCTACAAAATATCATTTTTTTTGGAGAGAAATTTAGTTTTTTTTTGGAGAAAATTATCGATTTTCTGGAAAAAATTATCGATTTTTCGGGGAAAGATTAATTACGATTATTTTAAAAGAAAATTATCGATTTATATTGGGAAAAAAATCACTGATTTTCTGGAAAAAATTATCGTTTTTTGTCGGAGAAAGAATATTAAATTTTTTGCAGAAAATTATCGTTTGTTTTTTTGAAAAAAATTTCCGATTTTTCAGAGAAAACTTTTTTATAAAATTATGGATTTTTAAATATAAAATTAACGGTTTTTAGACGCTGGAGTCTTCAAAATTGCGAGATCGATTTTTTTCTGGAGAAAAACATATTGTTTTTTTTTGGAGAAAAATTTCGATTTTTTTGAAGACATTTATCTTGGTGATTGTTGATAAAATTATCGATTCTTCGGGGACAAGTATAGCTTTTTTTGGATGAAATTATCGATTTTTTGGGAGAAAAAATACCGATTTTTTCCGTTTGGATCAAATTACCGTTTGAAAAACAAGTATCACAATTTTTTGAAGAAAATTGTCAATTTTTTTGGTAATAAATATAGTTGTTTTGGATAAAACGAGATTTTTCAGCTAAAAATATAGATTTTTGCTTTTAGATAAAATTTTGATTTAAAAAGAAAATTATCGATTTTATGGGTAAAAAATAACGTTTTTTGGATAAAATTATGGGTTGATTTCTTCGGGGTTCGTATAAATATTGATTCTGTCGGGGAAAATATTTTTTGGATAAAATTATCGATTTTTTGGAAAAAATTATGGGTTTTTTTTGAAGAATGATTTTATTGGTGAACAATATCGAATTTTTTCGGGAAAATATCGATTTTTCGGAGAAAATTTCTCATCGATTTTTAGAAATTATCGATTTTAAATTGGGTAACAATCTCGATTTTTTGAAGCAATTCTGAGCCAAATTTTGAATTTTCGAGCGGCAATTTTTGCACAAAGCATTATAGGTTTGACGCACAAAATTCGAATTCTTCAGAATTAGTTTCACAAAAAATTCTATCACCTAAAACTAGTTCACATGTCCCGTTTCATCTGAAACGCTGACATTTTTTGGCTTCTCCACGCTGAGCTCGAACCAGCTCCTCCACTGAACATCGTCTCCATTCGTTCATCGGCTCGGGCTCTCGACTGCATAGCCTCAGGCGCCGCGCCTCGTTTTCCGCCTGAATTTGCCTGTCGAGCAGACGCTGCGCATCTTCGGCGGCTTTTCGCTCGTCTCGGCGAACCCGTTGTTGGATTTTGTCCGAACGTGCCATGATTTGCCAAATGATGGAGAATGTATCATTCATCTGGAAGCGGAAATTATAGAGCAAACCAGTTGATAATTGTGCTCGAAATTTGGGGAAGAAGCGCAACCAAAAAATCAATAATTACGTCCAAAAATCTATTTTATTCAGAAAAACCAGAAAGCGATTTTTTTTCCAAAAATAAATAATTTTCGTGCAAAAATCGATAATTTAGACCGCTTCTAAAAGTCTCAATTTTTCCAACAAAGAAAACAATCTCGAAAAACCGATGTTTACAGAAAAAACAAAAAGCAAAAATTCATAAAAATTAAAAAATTAAAAAAAAATCAATAATTTTTCTAAAAGCGATTTCTTTTTCTAAAAATCCTTGCGTTTAATTTTCTTCTGAAATCGATATTTTCCGTTGCTTTTGGTTTCGTGAAAAAAATCGTCTATTGAACATTTTGCTAAATTTCGAAAAAAAATCTTGAACGATGCACCATGATTTTGAAAATTCTGCTCTGGATCAATTTTTCGAGAAAATCGATTTTTGGAAACTATCATACAAAAATCGACTGCTAGTTGTGCTCGAGATTTGGCTCTGAGGAAAAATCAAAAATTTTCTTCTAAAAATCGATTTTTTATCCAAAAAATCAATAATTTCGTCGGACAAACCGATGTTTTCAGAATAATCAAAAAAAAAATTAAAAAATTAAAAAAAAAATTTCAATACTTTCTAAAATTTTGCGATATCTTTTCTAAAACTATTTAATTTTCTTCTAAAATCGATATTTTTGATTTTTTCGTGAAAAAAATCGTCAATGTTATTGAAATTTTTGCTTAATTTCGAAAAAAAATCTTGAAACTTCGATGCACCATGATTTTGAAAATTCTGCTCCGGAACAATTTTTCGAGAAAAATTTATCGATTTTTGGAAACTATCATACAAAAATCGACGGTAATTGTGTTCGAAATTTGGGAAGGAGGAAAAATCAATAATTTTTTTCTAAAAATCGATTTTTTTTCTACGCGAATCAATAATTTCGTAACCGATGTTTTCAGAATAATCAAAACAAATTTCAAAAATAATAAAAAATCAATAATTTTTTCTAAAATTTTGCAATTTTTTTCTAAAAATCGTTTAATCTTCCTCTAAAATCGATATTTTTCCGGATTTTTTCGTGAAAAAAATCATCAACTTTATTGAAATTTTGTCATACTAAATTTCGAAAAAAAATCTTGAAATTTTGATGCACCATGATTTTCAAAATTCTGCTCCGGACCAATTTTTCGAGAAAAATTATCGATTTTTGGAAATTAGCATACAAAATTCGATGTGCTCGAAATTTGGCTCTGGAAGGAGGAAAAATTAATAATTTTCTAAAAACCGATTTTTTTTCCAAAAAATCAATAATCACGTTCGGCTAATGGAAAACCGATGTCCTTTCAATCAAAACAATCTCAAAAATAATAAAATCACTAAATCAATAATTTTGTCTAAAATTTTGCAATTCTTTTTTCTATAAATCGTATTTTTCCGATTTTTTTCGTGAAAATAACTCGTCTTTTATTGAAAATTTTGCTTTTCGATAAAACGATGATTTTGATTTCGATGCACCATGATTTCGAAAATTCTGCTCCTGAGCAATTTTTCTTTAAGAAAATTACGATTTGTGGAAATCATCACACAAAAACCGATAATTTTGTGAAAAAATTCGGTTTCGCACCATGATTTCGAAAATTCTCAGAATTTTAGAAAATTTATCGATTTTGTGTAGAAATTCGAATTCCAGTGGAAAAATTTTCTTTGTATTTCTCAAAAAATGTTTGATTTAAAAAAAATCGATTTTATGATCTGAAATTCAGGCATTTTTGTAGGGCAAAGTAAAATGGCAAAATCGATGATTTCTCTGATGAGAATGGGAATTTTTGTCAAGAAAAATATAAAAAATTCTTAAACAATTAAAGTGTTGTCAAAAAATTGAAATTTTGCGGAAAAAAAATATATTTACAGATGAATTTTTTAGAAAAATTCTACAAAAAGAGGTTCCATCTAATATTATTTTGTCGCATTGGGAGTTTATATCACATAATTTTTTTTTGTTTCGGTTGCCGTGGAGAATGGGGGTTGCAAATACCAATATCACATTTTTCAGAGGAAAATCACAACAAATATAAGGAAAATTTAAAAAAGGCGCGGGGGGAAATTCACCAGATTATCGATATTTATGGATAATTTCCACGATTATTTTTATAGCAAAATTGATCCGGAGCAGACTTGGGATAAAGCAAATGTTGGAGGGGGAAAATGAACAAATTGATAAATTATAATATATTCGGGGCAAAAAATGGGAAATAATTAAATTGTCGGAACATATAAATGATTAATTGATTGAGGCCAATGGGATTGGTTTCATGTGAGCCAACGCTTCATTACAGACCACTTCCTACCGATGACGTAGCGGCCATGAGAATGCTCGACACGAGCAAGACGGTAGGTTCTAGAGGCGTTTATCTGGAAATTTTGTGAAAAAATGAAGAAAACAAGCTTTCTTCGCTGAAAATTCCAAGATTTTCGGTCGTTTTTTTTTTGCTAATTTTTTTTAAATTCGCCTTGAATTAAATTTCCAGATGTTCAGTAACACGTTTTTTTCTCCTTCAAAAATCGGTTTTTCAATTAATCAAATTCAGAGTATTAATAATTATTTTCCTCCACCAGAATTTGAATATTTTATCCACATTCTGAAACCGGCTCACAGAGCGGCTATTACTACGTGGCCTAGAAAAATCAAACGAACTCCGCCAATGATTTATCCCGTGGCGATTTTTGTGGGATATTTCGGAAACTTGACGAGAATGTTCTCGAATGGTCGGGGGTGCTACAGTTCCACCGTGGCGATTTTTGAGAATATGTTCCGTAGTTATGAAGGTGGCCGAGGGTTGTTTTCTTATTTTACGGCCACGTAATAAAAACCGATCTGTGGGCTCCTGAGCAGAATATCGAAACATATCATGGTGCATCGAAAATTTCAAAATTATCGATTTTTTTGTTGTAGCAAAATTTTCAATAAAATAAGAAATCATGGTGCATGGACAAACCAATTTTTTCCTTTTTTTCGAATTTAAAATAAAATTTAAAAAACAGTAAAATTCTTGAATTTTACTTTTTAAAAATATTTTTTTCAAATTCTGGCAGTTTTAAAATAATAAAAAACGTTTTTTTTTCCATTTTTTTCAATAAAGTTTTTTTATGCCATGATTAGTACTACTAATGTAAAATTTACAGGGTTTTCACAGATTTTCAATTTTGTTGATTGGCTTATTCGTTCTTCAAAAATTCTAAATTTTCAGGTTTTCTTTTCCATTCGCCTTTAATTTTTGGGAAAAAACAATGTTTTTAATTAATTTTTCAGAAGGACTTAAAAAATTGTGACAACTAAAATTGTTCAATTTTTTCCGCAAAAATAATTTTTCGGAAATCCGCGTTCAAATGTCCTACAAAAAACCCCTTACCACAGTAAGCCTAACCAACTGTGAGAGCTCTCTGTTCATCGACTAGGGCTCCGTCGAAAAGCCGCCCAAACTCTAGAGCCGACGCCGTATCGACGCGCACTCGAACCATCTGAAAAACCAAAAATGGAAGAGCTTCTAATTTTTCGTCCAAGGCAGGCCATTTGATCTACGTAGATCTAGAAAAATTGCGAGAAAGAAGAGACGCAGAGTTCTCAACGCTTTCGCATGATTAGGAGTGTGTTGACGTCACATTCGCAAAAAATTCCCGCATTTTTTGTAGATCAAACTGTAATGGGATGGGACCACGAGCAGTGTTAGGCTGTACCATTACGGTTTGAGCTACAAAAAATGCCGGAATTTCTTGCAGAGGTCAACACACTCCTAATCATGCGAAATCAGTTGAGAACTCTGCGCCTCTTTTTCTTGTCCTGCATTTTTGTAGATCAATGTATATAAGCCTCTCTCTCTCTCACCTGAAGTATCACCGCTTGCTCCAACACAATCAGAACATCACAAAACTTGCTGGCAATCGTTTCGCGGGTGTACACTTTCCGTGTGTTCTCACCACACCACATGCCCTCATCGTTTCCGATATGCTTCCCTTGTGGCTGCTGCACAGCCGTTGAGTCGTGCTCACATGGAATATCACCTCAGCCTCGGCGTCTGCAAAGTACGGAGCCCGTGTCTCTACGGGCAGCCACCTGTGTAATCATCGTGTCCTCGACCCACTTTGACCTCCCATCCGAGCTCCGAAGCTATTGCGCGGGGGCGGATGCGGTGGTGTTGGACAGGATCGATGCTCGATCCTCCGGCGATTGTCCTAATAGATCACATCGACTTTGTGGACTTCACGAGAACAAGTCTGATCTAAATGCCAAGTCACGGGGAAATTCTGCCGTGAACCTGAGACACAAGTGGGACAGGAATCCCCGGGAAGCCGACAGCGATCTCCATTCGACTGTCGCGTTCGGAGTGAACGCTGGCAAGTGATCGTGGGGCGCCGACGATGTGGAGGCTGTGGCTGCCGTCTAGACGTCTCAATCATCGATGTAAACTGTGCGGCACCAAGGCGGGCTCGTGACGGGGGATAGGTCCGGTATATCATCCGAACGGATCATCCATCGCGGATCCCCTGGCTTTCCGGACCGGGACGTTTTCCCTTGAGAGCCTCTTTGCGTAGCCAATTGGTCACATTGGTGGCAGGCTTGCGGACATCCGGTTCTAGATCCAGATATGCCGGCCAACTAACGTTCGGGAAGTGATTTCGCAGGGGAATTTGGCGTAGAAATCCTTTTAGACGGGACACCGAGATTAATCGCCGATTGCCTATTAATATACACGGTTTTATGCTCTCCTTGTAGTGGCGGTGCTCCTGCAGAGCTCCATATCTGAACCTCAAAACCTCGCACCGGATTCTGACCACCGAGCGTGACAAGCTCTCCATGGGAGCACCATATCCTATCGGCCAAGATACCACGAATGACGATTGGCATTTGAGGTTTTGGCCATTGATGGGCATACAAGGCTTCACCATCTGCCACTCGATCTCGGTTCTCGTACGCTCATCGCGTAGGTGATGGAGCGAGGCGGCTCACGGAGCAGCGCCTGGAGCAGTGCTCGAGAACTGGGCTAGCGAGGCGATCGGCAGAAGAGCGGAATGGGCCGCATAGCGGACTCGATGGGTTTCGATGGTTAACGCGGTGAGCACCAAGACGAGTTGGGACGTTTTGCACGTTGAGGATGGCTAGCGAGTTACCACGATTACTAGGGCATTCTGCGATACGTCTGCATTGACAAGCTGATCGACAAGGATTGGCTCGGCTCCATGATACGATGAATCTAGCATTGAGAAACTTCAACGAGTGCGAGGACACCTTCGTGTCCTTCGAGCTCTTCGCCGCCTGCAACATCTTCGGCAAATGCTCCAGAGCTCGCGTACGGAGCAACATGAAGTGATACTTCGTGTGCCAGAGAGCCCACAGATCGCCAGAGCCACTAGTTGCACCTTGGATAGGAGTGCATAAGACGGATGAAGCAGAAAAGAATGTTGTCCGAGAGCAGTGGCGGTGGCGGACGGTTCCTTGATTCGTCGAGAATTGCACTTAGAGCCGGAACATAGCGGGGCAGCAGGATTGGGGGTACGGTAACGAGGGTGCGGCACGCGAGCCTTACGAGTGGGCCAGTGGGTGCAGCTATACCGGGAAAGCAATGTAATTTTTTTTTCGGGCTTTTTTTCAAATCGAATTTTCACTTTTTCTAAATTTTTTTGTAAATTTTCTAAAAATAATTGTTCGATTTCAGAGTACCTCATTTCTCCGTGCGTGATCTACGTTGATCACGTGACAAATAATGCGGGACTGATTGTCCATGGTTAAGAACATGCCGACGTCCTATTTTTTGGGCAAAAATTCCCGCATTTTTTGTAAGATCACCACAAACAGTAATGACAGCCTCACGTCGTGCCAGAAAGTCCCATTTCGTGCTTCGATTACGCTGATCTCAAAAAATGAGTGTCTGATTGTGCATGATTAAGAATGTGCTGACGTCACATTTCGTTTGGAAATTCCCCCATTATTTGTAGGTCACACCGTAATGGGACAGCCTGACACCACGTGATCTTCAAATTCCGGCCAGCGTGAAACCCAAAAGCAAGATCTCAATCGTCAATGACATGACGCAATCGATTGCCACGTGGGCACTCGAGTTGGTCTACGGATCCACGAGTGAGATGCCACGACGCCATGAAACGCCAATTCGTCGCCCGACAAAGACTGAAAAAGGGAAAAAGGGTGTGATATGCGCACGAGCTGTAAGAAAGGCTAATTAGTTGTCCACCTAAACAGGATAAAATGCTGAAAAGGCATTTTTCAGGGTCTATTTTCACAATGAGTTTGGGTATATTGGAGAGTTTTCCATAGATAATGACTGCGCAACTAATTTTGACGCGCATAATATCACGTAGCGAAGACTACAGTATTTAAATTACTACTGTAGCGCGCTGTGTGTCGATATACGGAATTAATTAAAATATTAATTGATAAAACAGAAACTATGATCAAAGAGACCCGTAAATGGACACAATCGCTACAAATTCAAAAAGTACTGTAGTTTTCGCCTACGAGATATTTTGCGCGTCAAGTATGCTAAGAAAATATGCAGTTGTGGTAGCCTTGTGAATTTTTAGAAGGTTTTTTGAAAAATAACTCGCCACTATTAAAAAAAATATATATTGAGGCTTTTCAAAGGGTTAAAGTAATTTTATACGTTTTTAAAATCGTTTTTTTTTAAAACTAAATTTTGAGCGTTTTTAGGACAATTTTCGTAACTTTTACGCTTTTTTTATGGCCATATTGTGTAGTTTTTTACACTCTGATATTCCAGAAATCGTCAGAAAAAGCACTTAAAACGGGCTAGAAAAACGGGGTTTTGGCTTGCTGCGAAACTTTTTTTTTTGAACCAAACTTACCGCGCAAAAATATATTGTCATTCAAGTAATGTTGCAAAATGTATAAAAAACAGGTTTTTAATGTTTACGATTTTAATACAGTTGTGACGTATTTTTTCTATTTCAATTTTTGCAAAATAAGAAAAAATATGACTGGAAAAAAGTTGGAAAGTTTTTAAAACACATTTTATACAGGAGCGGTCATTACGCTCTAAGATTTGCTGGCATAAGCGAGAATGGTCTTTGACACTACATATATAATATTAAGTCTCCAAATAAGTCCGGGTCTAAAATCATAAATTTGTTCGCTGTGTATCGATGTTTATGAAATTGTGGGAATTTGTGTTATCAACCCTGATCTTTCATTTGATGGGCAAGAGTCACAAAATTTTTTGGCCGTCGGAAGTGCCCCGCCGGTACTCGCAGCCAATTTTTTCAGACATGTTTCAGATCCCGCTTCTTTTCAGTTTTCAACTGAGGATGGTGTGCGGAAGGTCTATTGCTTAGTTTAGTACACAATGTAAGAAAACAAAAAAGTTTGGAAAAAAATCCGTCCAACAGAAATAAAATATGTTTTTTGTCGCTCGTCAAAAAATCTACAAAATTTTGTCGAAAATTATTTGAATTTTTACACCCAATAAAAATGATGTAACCGTGTGCAAACTAATTTTAATCACACAAAACGACTTATGAAATTTGGATCGAGGAATACTCCATTCTAAAACTCGATAATAGTTCGAAAAAGCTGTGTTTTTTGTTATTTTTTTTAGTGTGATGCACCAAAGTGAAATTTTTTGTATGTGAAAAAATAGTTTGCATGGTTACATCATTTATAAAAAATCGAGAATTTTCGAAATCTGATTTGTTGAAGATTTTTTGACAACCGACAAAAATAATTTTCTTTGGACGGATTTTTTTCCAGACTTGTTTGTTTTCTTACATTGTGTACTAAACTAAGCACACGCACACAAAGCTCGATTGAAAACTGAAAAGAAGCGAGATCTGGAAAATGACTGAAAACTGGCTCCGAGTTAGGGCGCTTCGGACGGCCAAAAAATTGTGACTATTGTCAAATGAAAGATCATGTGGTTGAACATAAATTCCCAAAGTTTCATAAGAATCGATACACAGCGAACAAATGCTGTTATGATTTTTGACCCGGATCCTATTTGGAGACCTAATATATATACATAAAGTATACCTACCGTAACCGCAATCGTAATATCATCACTGTCATGAAAAACGTTATCCTCTGCAATTGTATTCGACGAGGACATATCTCCAGTCTCTGACAATCATTTACTCGGGTCTTCCATCATTGCCGATTCGAGAATTGCCTGTCGTCGACTGTTCTGTGAGAATCCGGTTCTGTCGCTTTTCGGAGAGCTTCTTCACAGAATATGTCGATATGGGCGAGATGGAGGATTAATGCTTGCGTTCCACTGTTCACAATCTGAAGACGTTTTATTTTTTTGATTTTGGCTGGAATAAAGCTATGCTTTTGTTGAAATTTCAGTTTAAAAACATAAGGTTTTTGAACTGAAAATTGGGATCCGGAAAGAATTAGAAAAAAATTTGTTTTTTCTCTAAAACTGCTGTATCCATTTTATTCAATTTTTTAAGATTTTCACAAAACATAAGAATTTTTGTAATTTTTTTTCCAAATTTTTTGAATTTTCAGCAAGAACTGGACAAAAAAGGCACTAGTTTTACTAAAATTGGCAGCATTTAGGAAGCGGTTTCTGAAAAAAACAATTAATTTTCATTATTATTGTCATATGATTACAGGAACACACTATTCTGGACGTAGTATGCGATTACACAACATATTTGACGCGCAGAATATCTCGTAGCTTACAGTAATTCTTTAAAAATGACTACGTAGCGATTGTGTCGATTTGCGGGCACGATTTTTTGATATGAATTTTAATCATATTTTGAGCAAAAAATGGCTCAAAAAACAAGCCCGTAAATCCACACAATCGCTAACATGGTAATTTAAAGAATTACTGTAGTTTTCGCCGAGATATTTAGTGCGTCAAATATGTAATACGCATTCTCAGAATTTTTTGACTTTTCCTATAAAAAAAAATCGTGATCAAAAAAAATTTTTAATTGTATTTTAGGATGAAATTACGATTTTATTCGTTCTCTATAAATTTTGAGCAAATATATTTCAAAAAAAAAAAAAATTCTTTCTATATTTAATTTTTTTTTCGAGTCGAGCTTTTTTTTCTATCTTCTGTACAAAAGCAATTTAAAAAAAAGGAAAAAAGATTAAATCTAGAGTTCTAATTTTCCTCCGGGTTCTGGCCATCCTCATAAACAGAATGGAAGAGTTTTTGCCGAACTAGGCCATTTTGCAAACTCTTCCATTTCAATTTATGAGGAAGGCCAGAGCCTCGTGGAAAATTAGAAATTAGAGTTTCGAAAAATCTTAAAATTTTGCCCGTAAATTTCTTATTAGTGTGTTTTGTACAGGAGATTGAGAAAAAAATCGGCAATTGTATACAATTTAATTTTAAAAACTTATATAGTTAAACATAAATTCAATGATCTAACTGGAAAAAAATGTTTACTTTGAAAAGTTAAAAAAAATGACAAAAATGTAAACTCAAAAATTGAATAAAATGCGGCAATTTCATAAAATAGCTTTTTTCCATAGTTTCTGTCAATTTTCGGCTAAGATTAATTTTTTCTCATCAAAATTTACGATTTTCATACTCTCTTACCGAAGCCCATTGACATCGGTATCCAAACACCCTTCTTCATGACGTCATGATACACCTCATCCCACACCTCATCGTCAATTCCGAGTATGCGTCTGACGCAGGATAGCCTTAATCACGACTGGGATATTCGAGATGAGTGTCGACGTAAAAGCAGCCGACACATTCTCGGAAAACGCGTCCGATTGGCAGACAGATTTTCGAGGCCCATGTGCTTAAAGTGTCGCGCCCTTTCTGAGCCGGAGAATTTTTAGGGAAGCGGTTTAGTGTTTTGAATTCGATGCGAAACCAGCTGCTTGCACGATGTTAGAATCGCAAATGCTATGGAGATAGCCGAGGAGTGACTGGAAAATTTTTTCTTAATTTTTAAATGGCCGATTTTGGGAGGGTTAGTCGAAAAATTTAAAACTAGGATCTATGAAGTTTTTGTCACACGGCAACTTCTGGTTTTTGGAATTTCGCCACTTTTTAACAACCCTGGCAATGCGTGCAAATTTTTGGAAAACCGGCAATTTATGGTGACCTTTCGGAATTTTGCTAATATGAAAACCGGCAATTTGCCGCTTTGCAAATCTTAGGAAAACCGGCAATTTGTGGTTTTTGGAACTTGGCCACTTTTTATCAAGGACCTACAAATTGCTTGCAAATTTTTGGAAAACCGGCAATTTCTGGTTTTTTTTTGGAATTTTTCTAACATTTATAAACCGGCAATTTGCCGATTTGCAAATTTGTGGCAAACCGGCAATTTGTGGTTAAATTCGGCTTTTGGAATTTTTCTAAAATTTTAATGAACCGGCAATTTGGGTTTGCAAATTTTTGGTAAACGGGCAATTTTTGATTTGGAATTTTGCTAAAATTTTTAAAAACCGGACAATTTGCAAAATTTTGGAACAGTAAACCGGCAATTTGTGGTTTTTGGACTTTTGCCACTTTTTATAAACCGACAAAGTCATTTGCCGATTTTCAAATAGGCCAATTGCAGGTTAACCTAAAAAAACATTCCAAAAAAACCAGAAATTGCCGGTTTTCCAAAAATTTGAATATCGGCAAATTGGTAGGTTTATAAAAAATGGCAAAATTCCAAAACCGAACCACAAAATGCCGGTGTTCCAACTCTTTCAACGAGAGTATCCAATTTTTTAAATAGAAAAATTGCCGTATTCCATACCGTTCTCCACACATTTGCCGATTTTCAAATTTTTGGAAAACCGGCAATTTTTGATTTTTGGAAGTCTGTAAAAATTTTTTATAGCGGTTAGTGGTCTATGGATGTCTGTCACCTTTTATCTAAACTTCCACTTGCCGGTTTCAAATTTTTGGAAAACAATCTTTGTAGATTGTTCAAGTCTGCTAACTGGCAAACTGGGAAAATGCCTTAGTTTGGAAGTTTAAGGTAAATTCTCAGACACCGGAATTTTGACATTTTTCAAACTTCCAAAAACCACAAATTGCCGGTTCGCCAAAAAATTGCAAAGCGGCAAATTGCCGGTTCTTAAAAATTTTTGAAAAATTCCAGAAAAACAAGAATTGGCGGTTTGCCAAATTTGCGAAATTCCTACAACTGGAAATTGACGGTTTTCAAAAAAAAACAAAGAAGGGAAATCGGACCAAATTACAGACGCTTACATAAAGTGGCAAAGTTGCAAAATCCAGAAATGATCTTGCCGGTGTGTCAAACTTGCGAACACATTAAAATACCACAAATCAAATTGCCGGTTCCGAAAAGGTGCAAATCGGCAAATTGCCGGTTTTTGAAATGCAAAACTCCCAAAATTTACAGAAAAAATTCCAATAATCAAAAATCCGAATTATTGTTCCACAATCTTCGGAAAAATTATTACAAACACAATCAATTTTCCAACTTTTCATCAAGCGTATTAGCGAAATACAATCGCAAAAATTTCTCGTAATTTATTTTTGATCTACCACTTGTCGTTGACTAGCCTCCGCCCCTCATCTTGTTGCTGTTGTTATAGTTGGTGGCTGTCTAGTTGAAGGAAGGGGCGGAGCCTATTCAACGAGGTAGATCAAAAATAAATTATGAGAAATTTGTGCGATTGTATTTTTTTTGTTCGATAAAATACCCCAATTTTTTAATGGAATAACAATTCCCTACCGTACTACATTGAGCCAAATACGGACTGTGAAGCCCAACAAGATATTCGAGAGCAACAGAATAGCGAGCACGTTCAATCGATATTTCTCCAGACGCTACGAATGGTGGAATTTCGTACTGGAAAAGCCATGCGGAGAGCACATTTACCACTATATGAGTGACATTTGAGCAAATGCCAAGGGGAGTCCTATTTCATTGCTTCACGCATTAGTGTGAATGCTACATTTGTGCCTGGAAAAGGACAAATAAAACTATTTTATTAAATGTAAGTAATTAATTTATTTTTTGAAATCTCTTTAAATGCGGTGTAGTCGAATATTGTTTCAATTGCTTACCCTCAAAATTGTCTGAAAACACCGAATTTCATAATGAACTTCTTGAAAACTTCTCAGAAAAATCTTAGTTATGACGCCTCAAAAAATGAAAATTGGTTAAAATGTGAAATTTGACCTACTTGCCAAGCGGCTGCAAACTATCCAGCTTTTTTTTGAAATCAATGTCAAGTTTTGAGTATTCAATTTAATTATCCGTTTTCAACTCGATTCAGGGGTATTTTAAAGTCGCTATAAACGAAGAGTTTTTTAAAAATTATTTACCAAATCCTTCTACCATCGATTTAAAAATACCTAAATTTAGTTCAAAACGCAAAATAATTAAATTGAATACCCAAAACTTGACCGTGATTTCAAAAGAAACTTAGTTTCCAGCCACTTGACAAGTTGGCAAATTTCAAATTTTAACTTTAGGCAATTTTTTAGAGCGGTCATAACTTTTTTTTTTGGAGAATTTTTCAGGAAGTTTCATTATGAAATTCGGGTGTTTCGATCAGATAATTTTTAGTATAATAAAGCAATAAAAAAAATTCTACACCAACTTCAATCGAAAATGTAAACAATTTTGTTTTGAAGGCGGTTTTCTTTTACTTTTCTAAAAAGAAATATTCAATTTTACGATTTTTTGCGTAAAAAAACACGGTCAAATTTTTGTTAAATTCGAAAAGATTGGCGTGTCCATTACGGTTTGACCTACAAAGAATGCGTGATTTTTTAGCCAAGTGTGACGTCAGACACATTCTGCGTCTCTTCTCCCTCATTCTTTGTAGTACGTAGATCAAGCCGAAACGGGAGAGCCTGACACCACGCGCGTGTGCGCCTGTAAAGTGAGTACTGTAATTTCAAAAAATCCACAACATCCAGAGTTTGAAACTACAGTACTACTATTTAAAGGCCACACACTTTTTCGAAACAACGATAAATTGTGGTGTTGAGACCGTATTTAGGGCTCAAAAAAAAAATAATTATCGTTAGAATATGGTTCGGGAAAGTTCCTATGCAGTTTCACTGAAAATTTGAATTTCCCGCCAAATAACGAATCTTCATCCGAAAAATTTGAATGCCAAACAATTTTTTTAAATCATAAATTTGAATTTCCCGCCATAATCGTATTTCTCAGAAAATTTGGATTTTCCATGCCAAAAATAAAAAAAAAAATTTTGGCGCGGCGAAAATTCAAATTTTCTGAAAAAATAATATTTCGGCGGGAAATGCAAATTTTCAGAGAAATTTTTTGGCGCAATTTTTCCTCGAAGGAATTTTCTTGATGTGTAAATTTCCAAAAATTTCAACGAACCCAAATCGCATTTTTCTTATTTTTTCCCCAAAATTTTCAAAGTTTCTCGTACAACGGAATTTTATGCGACGAAAAAAGCGCATTTCGATACAAAATCATCGATGCATGTGTAGTTTGTAGTGTTGGTTGTCCAGCCGTTGGGTGAGTTGCCGTTGCATATTATTTCCATAGAATTAGGCAATATCTTGCAATTACCACCGGCTGTATTCACCAATGGTTCCCTACCATTCTCATCGGCTGCTTCCCAGCCACCGAACGACTCCGTTCGTATCCAGATTGAAGCATTCGCCCATGTGTAGCCACTTTATTACTCTGAAAATTGAAGAGTTTTATAGGCTCCTCTTACATCGGACATTGAGGTGATTTTTCGAATTCTTTAAAACAAAGATTTCCTGAAATTGAGCTTTTGGAAAATTTTAAAATTAGATCAAAATTTCAAAATCAAAAAAAAAAAAACAAGCGTTTGTACAAAATTTAAAGTGGAGAATTTTTTTTAGATTTCAAATTTTTTAAACATTTCTGAGTGCAGAGTCGCAAATCTCAGGCCAATCGGCTTCGCCGAAATTGAAAATTTCTCATATATCGGAAATTGCCGAAAATGAAAAACTCCGGCAAGTCGGCATATTGCCGGAATTGAAAATTCCTTACAAATCGGCAATTTGCCGGAATTGAGAAAATATCCGGCAAATCGGCAATTTGCCGGAGTTGAAAACTTCCGCCAAATCGGGAATTTTTGCCGAAATTGAAAATTTCGTATAACTCGCCGATTTGCCGGAGTTGAAAAATTCTGGCTAATTTGAAAATCGCCAATTTGGTTGGCCAAAGTTGAAAAACCGGGCAAGCCAATTTGCAGATTTTTCGAAATTTGACCGGCAATTCCTGTCGCGGACACCTTTTTTCCGAGAAGAATTAACTTTCCATTTCTCATTGAAAAAGTCAGTAATTTGCCGGACTTGACAAATTTCCGGCAACTGGACATTATGCTGAAAATGAAACATTCTGGTAAATCGGCAAACTGCCGAAAATGAAAAATTAAATCGGCAATTTGCCGAAGTTGATAATTTCCGCCAGATACAGGGAATTTGCCGAAACTGAAAATTATAAATCGCCGATTTGCCGGAGTTGAAAGATTATGGCAAATTTGCAAATCGGCAATTTGCCAAAGTTGACAAATTCCGCAAATCGCCAACTTTCTGCCTGTTGTGTATATTATTTTCACGAGTAAAAATCGTAATTAATTTAAATTAAATTTGCTTTTCGACCGAAATTTGCCTACCGGCAATTCCTGTCCTTTTTGCCGAGAAGAATTTAAATTTCCAAAAAAATCTTTAATTTGCCGGAGTTGTTTCTGGCAAATTTGCAAATCGGTGTCATACTTTGCCGGAGTTGAAAAATTCTGGAAACCGGCAACCCGGCAAACCGCCAAGTTGCATTTTTCGAGCGAAATTTTTTTTTCCGGTCGCCCCCTTTTTCCCTGAGAACAGTTAAATTTCCAAAATTCTCTAAAAACCACAAACCTTTTCTCAAAAATTCGCACACTTCACTCCTGTCGCTTCCCCTCATCATTCCACTCAATCCGCACATTTTCTCGAGTACAGCACTCCAAAAACTTGTCCAAATAAACTTGGAGCTTTTGAGCCCGTTCTTTCGAAGTCTGACGCCCACGCTGTTAATCGGCCCATTCCTCAGTCGACCAATCACCGGCTCCCGACGATTGACAGTACTCGTTGAGCACATTCCGCATTTTCACCAGTCTGTGTAACGGGAAGACATATGGTAGAAGCCAAAGTAAGACACGATCCAGGTCTGGTGTGGCTCTTCCGTACACTCCGAGACAGTGATAGAACACTAGGAAAAAGCGAATCGCAATTCTTCGCACTGCCATAATTTTTCGGGTACGACTGCTTTTTTGAGAAGCGATTCGATTGCCGTTGCCAGCCTGTGAGAAAAAAATTTAACTTAATTGTTATTTAAAGGTGGGGTCGCGCTAGTGGGGAAATTGCTTTAAACCTAGGGTACCACAATGACCGAATTTCATGATATAACAATTCAAAAAAATTTTCTAAATTTTATATGATTGAAAATTGAAAAAATCCAGTTTTTGTCTAATTTTGAATTACCGCCAATTGAACTTTTGTTCTATGGAGCGCGCTTGCACGTTTATCTATTAAATTTATCTACTTTATTTTTTTGGTAATTCGTTTCTGTTATTTTTCCACCAATTGTTAATGTTCGCGGTGTATTTTTGCTCGAATTTTAGAGAAGAAGTCAAAATAAATGCTTTTCGATTAAAAAAAGCACGATAAAATCAGTGAAATTAATTAATTAACAGGTTTGAAAACGTTTAAGATACATTTGTCATTTTTACGCCTGTAACCGTGCATTTTAATTGAAAATTTGTTTATCTGGACTTTATCTCTAAAATTCGAGAAAATACACCGGAAACATTAAAACTCGGTGGAAAAACCTACAAAAACTACAACATAAAATAACTTAAAAAGCGTGCAAGCGCGCTTCATCGAACAAATTCATTTGGCGGTAATTCTAGAAATTAGGGGGGAAAACTGAGATTTTTTCAAGTTTCAAAAAATCATATAAAATCTGGAAAATTTTTTTGGATTTTCTATCATTATATTGGGTCATTACCATAGGCGTGTTTCAAAGCAATTTCCCCACTGGCGCTACTCCACATTAAATCTCTGACGGTTTTTTTTCGGTTTTCCTTGAAAATCCTCTAAAAATCGATTATTTGTATTGCGTTGTTTTTCCGGGATTTTTCTCGGATTTCCCACGGGGTATCCGGCCTTCCTCACTGAATGTTTCGCTCCATTGACAATGTCTCGCGTGTACTCCACACGGAAAACAAATCACATTTAGTTTTACATAAAATTGACCAGAGACGCGGCAGCCAACGCGCCGTAAATTTACCCCAGATGCCTGGCCTAGTTCGGCGAAAACCCTTCCAGTTCAGTGTATGAGTGAAGCCAGAAATCCATGTTTTCCTCGAAAAAAACCTCTAAAAATCGAGTTTGTAATAAAAATTGCGTTGTTTCTTCGGTTTTTTTTACAATTTGAGGGTTTTTTGTCTTTTTGTTTTAACACGGATTTTTGGCTTCCCTCATATCTTGAAATGGAAGAGGCCTTTCTGCCGAACTAGGCCTGGCCATAACTGGGGGAGATTTACGGCGCGTTGCGTAACAGTGCCACGCGTCTCGATTTTAGTTGTAAAAGTAAATGGACTCATTGTCCGGGTGGAGTACGGCGATTGTCATTATGGAGCGCGAAAAGCAACGAGGAAGGCCAGAAGCCCGTGCGGAAAGACGGGGATCTCAAACGGGGACAATCTACAAAAAAATTAGTTTAAAAAAGACTTCCTCAAAAAAATTCGAAAATTGTGGTTTTCTCTTTTTTTCATAATTTTTTGTATTTTGATAAATTTTTTGCGACATCAAAAAATGGAAGAACTTTGTTCGCTTTTTGAATTTTTGGTGAAAGAAGAAAATTTCGAAAATTCGTTAGGGAATCGATAAATTTTTATCAAAAATCGATATTTTAAAATTATTTTTTGCAGTTTATAAAAAATCAAGATTTTTTCGCATTTCGCGCGTAATTTTCATTTTTGTCGTTTTTTTCTTAATTTTCCGAAATTTCTGAAATTTTTTCTTTTCTTGTTCTGAAGCTTATGCCTAAGGACCTAAGCCTAAGCCTGAGCCTAAACTCCTAAAACGCACCACTTCCAACCAGCTCCGGAGCACAGAGCACCTGCTCCAGTGTACAGAGCCTGGATTCAGCCTCAATTGCACTCGATTTGGCTGACGTCGCTGACGAGCAGAAGCTCAACGAGATGAAACGTCTCGAAACTATGCTCATCTTGGAGCAGTGGACCAGCTTTTCCTGTAGAAATGTTGTGGTCGAATTAATGCGAAATATGGGAAAATTCGGGTTCAAATCGATGAAAAATCGTGCAAAAACGAACATTCGTCGTTAATGTGTCGAGCTCTTTGTTTCAAGGCACACGGCTCACACAATCCCTGTTCAAGTCGGTGAATCTTGAAATGCTCACCTGCACATCTGACGATTTGCCCTTTCGGGCAAACATTTTCCTGTGATTTTAGGCGATTTTCTGCAAATTTTCGCTGTTCAAACGTTTAAAATCGACGGGAAAATGCGTATTTTTTACGAAATATGCGAGAAATAGTGATTTTATTCGAAAAAATCAATATAAATAAGGAAAAGAACTACAGGAGTAATTTAAAGGCGCATACCTCGAAAGTTAAAATCGTGCCAGGACCCGCCGCAATTTGGAATCGGTTTTTAAATGAAAACTTTTTGCTTTACTAAAAATTAAAATTCACTGAAAATTTCGGTTAAACTCTGACTATTAACACGAATCTTATCACAAACTATGACTTTCTAGTGACAATGGCCAATTTTGTGTGTAAAAAATTTTTTCAGTGTAAAATGTTTTTTTTTGAAACTAAAATTTCGAGCTTGAAACTAGAAAATGTCAAGTAAAAAAGTCGTGCATTTTTAAGCGAAAAATAACGTTTATTTCCAAGTTTTCGCCTATAATTCACACAAAAAATACTGACTCAGCAAACAATGTAGGGAGCATCCCGAAAATGGTGATGGTAGAGCAAAAACGAAAAGTCGATGAATTATTTTAGAGAGAGAGGTAATTTTATACAATTTTTCAGGAATGGAGGTTAAAAAAAAGAGTAGAAACCATTAAGGCAAAACGATCCAGCTTGAAACCGATTTAGAAACTGCAACTCCCAGAAAACGAAGCAAATAAGAAAATCCCACAAAAAATCCGAATTTCATTGCAGTTTTCGACCGCCGTAATTCAGCCAACCAGGGTGAGTGTTCAATTATTAAAGAAGAAGCACATATATACATATAACATTATTCAAAGGACATAATCCATATAAAGTCTGTCAAAACGGTAAAGGTTCTTGTATCCAAAAACACATTTGGCCCCCTCTTTCGAAAAGAGAGAGCATGGGAATCGGAGAGGACGGTGCGAAAGACCCAGACATCGAGATGACACTTTTTGACAGTCCAACAGCCTGTGTGTGTCTGTGGTGTGTGTGAGTCTCTGTGATTGAGTGAAAGCGCTTTTGGGAATATATAGTACCTGGTAGAAATTTAATTTAAAATGATAAAAAATTTCTTGGGATTTTTTTTTTTGAGTACTGTAGTACACCACAAAAGGACGTAATGTTCAACTGCGCCCATGGAGTCCCAATGACGTAATATCATGATAAAAAAATTTTGAAATTGGAAAAAACTCAGGTCTTCCCCCCCCCCCTAATGTCTTCCAATTAGAACTTGCGCCAATTGAATTCGTTCGGCGGAGCGCGCTTGCATTATTTTTATTATATTTAAATTTCGCTCTGTGTTGTAATTTCACTGATTTGTGTTCATTTTTTGGGGGTTTTTAATTGGCAAAAGAGAGAAAAATGCAAGATCAATGCAAATTGTTCACTAAAAAATCACTGAAAATAGGTAATACTGTGAAATATGCTAATTTCAGGCTTGGTGTAGTCGGAACTCATAATTTCGTAGTTTTACCCATAGTCTATCATTTTTTAATGAACATCTGCATTTATCTTTTTTTTTTAAATTGAATTGCTATTAAAAATCCCCAAAAAATGAAGAAAATCAGATAATTAGAAACAATAAAATAAATTTATAAAAATAATGCAAGTGCGCTCCACCGAACGAAGCCAATTGGCGGGAGTTCAAATAGCGAGAATTAGAGGGAAAACTGAGATTACTTTTTCAATTTTGAAAAACATCATAAAAAATACGCATTTTAGCTTAAAAACTCGAAAAATCATACAAAAATTAATCTGCACCAAGTTGTCCACGAGTAGTACCTTGCGTCGCCTGGTTGCAGAAATGGCATAGATTTCGATTAGATTAAAAGCTTAAAAATCATTTTTTTTTACCCAATTTCCATTTAAATATCCTAATTCCAGCTTAATCTCAATTTTCTTGAAAGAAGTGCAAATATAGATTAACGTAAAAATTCTACGCTGCGAGACCCATGCCCCCATAAATCGCCTGCGCCTTTATTGATGATTTATATTTATTTTCTCTCTCAACCAGCGATGAACATCACGTTTTTGAACGAATTTTCGAAAAAATAAGACAAATTTCTATTTTATAAACCACTTTATACCGTGGGTCGTCGCTAAATAGCAAATTTTGACGCAAAACAAAAACGAACAGACAACGGAAAATCGATTGAAAACAAGTGAGAACACAGCAAAACTAGTCCTAATTAATTAAAGGCGCATCACGTGGAAAAGAAAACTGTTGTGGAAGAATAAAAAATGGAACATGAGGGGAAAGATTACACTAAAATAGTAAAAGATGCAGCAAGATTAAGATTATTTCTCGTGGAAAAATCGAGTCCCCTTCCGCCCAGGAATTCATCATAATTTTCGACTTTTTTTCGGAGATTGCTGCACTTTGTCGGCTGCTCCGGTGGTTTTTGGCAGGTTTTGAGAGCGCTGAAAGATTTGAATTTTTTGGAATTTCGAGAAATTTCTTGTTTTCTACCCGAAGCGCTTTGAATATGGCCAGCTGCATTTCCAGCTTGCATTGTCCGTTCAGTGACTTTGACCCTTCCAGTTTTCTGAAAAAAAAACACGAGTTTTTGAATTTACTTTCTGATTTAACGATTTCTGGTTTCCCTCAAAGAATTGAAATGGAAGAGTTTTTGCCGAACTAGAGGCCATATCTGTAGATTTACGGCGACCGTTGCGTGTCGCGTCGCGGCTCGCTTTTAGTTGTAAAGCTAAATGTGATTTGTCCGTGTGGAGTACACTACTTTACCCTCCCACGCGTTGTCCGGCAGGCGATAGCGCGAAAAATTCAAAGAGGAAGGCCAGAACTCCGTGATTTTTCTTTTTCGCGTAGATTTCGCAGTTTCGGACTGTTTATCAGGTCTAATCAGCGGAATTTTCGGTGATCCCGCCAATCTCGGTTATTTTCTGAGCCTTTTTCGCTCAGGTTCTGGGATTTCAGCTGTTAGAGCAATCTTTGTATATTTAGACAAGTTTCTTGAAGTCCAACGCAATTTTTTCAGTAGTATTCACAGTTTCCGGCAATTTTTCAGAGCAACTCTTCGAAATTTCGACAAGTTTTCTGACAGACTTTGTAGATTTCGTCTGACGGTTTTTCTGCAAATCCCGGTATTTTCGGCTCGCGGAGGACTCCCAGCTGCTCTTATTGTTCAGCATTGTCTGCTCAGTAGCGGGCGCGTCTTGATTTTCAGTAGAATTCGCAGTTTTCGGCAATTTTTCTTAGAATCTTCAAAATTTTGATAAGTTTTCTGTTCCGGCGTAGATTTCGCAATTTCTGGCGGTTTTTCCGCAAATCTCAGTGATTTTGGGCTCGGGGAGCCCCTTCCAGCTTCTCTATTGTTCAGAATTGGCTGCTCAGCAGCGGGGGCGTCTTGATTTTCAGTAGAATTCGCATTTTCCGGCCACTAATTGTTCTGAGGTAATCTTTGGAATCTCGGTTTTCTGACTTTTGGCGTATACGCAGTTTCTGGTGATTTTTAACCCGGCACGATGAGCTCCCAGCTTCTTCATTATTCAGCCTTTTCAGCTGGGCTTCTTGAGAGCTTGTAATCACGTCCGTCGTAATTGGCCTCTGAATCATCATCCGAAACCAAATTGGCGTCGATTATTTCCTGAAAAAATCGATAAATTTTTTTGCTTTTTTTTGCTTTCTCATAGTCTGCTTTTCCCACTTTCCCGCAATTTCTCAAAACACGGCGTTGGAACGTATCCTGGTCGCCGATCGAACTGGATAACTGGCCGGCTGGCGATAAAGAGATCGGCGAAATCTGCTACTTTCTCGTCAGATGAAACCTCGGTTTTTCTGCTAAAACCTACTCAAAATTTCCACTGGCTAAAATCACCTGATAACATTACATTATCATCATTTCCGGGCATTTGTACTTGACGAAAAAAAAGCGGAAAATATTTAGGATTTCGAAAATGAAGCGAAGGTTACGGTACACTAAGGCACATGGCGTAAAATATTCCGCAGGACTCGCCGCGATTTAGGATTTTCACTATTTTTTTTGGGCAAAAGTTGACATTTTACAGAATAGAATACTAAATTGTGTTGATAAATTGTTTATTTGGTTTTCAAATTTAAATCTAAACTGTAAATTTTAAATGTTCCCCCAAATATTCGCAAATTCCCTTCAAACCAAGTTTTCTAGCACAACCGTAATCCCCGAGCAATCGCGCTCCACCAACCTACACACCGCGAATTTTGAATTACATCCCTCATAATTAATTGTTTTTGCCATTTTTTTGCTATTTCCAGTGGATTTTAATGAGTAAAAGCCTACAAACCGACGAAAATGGCGGTGTCAGTGTAAGTCCATCAAATACATATTTTGCTACACGCTGGAATGCTCTCTACGCATCATACACCTCATCAAGCAAGAAAAAGACTCCAATCTCCTCGAAAAGCGCTATAATGACTGTCTATACGGCAGAAATGAGCGCAGAGGTTTTAGCGAATGAATGCCTGTTTTAAGAGCAAGTATAAGAATTCAGAAAAATTCACCTGCAAATCGTGCTAAATACCACCGCTACCGGACAGCCCGCAGTAGTGTGCCATGACGTCACAGCAGTTGTACACTTGCAAAGCGTTGCAAAATGGTAAGTGTACTGTCGAAATTCGCTGTAAGACCTAAAAGACCACAAAAATGGAAAATATCTGAAAACCTCACGATGCTCGTTAATGTTCCAAATGTTCAATGCGCGCCGCGAAAGCTCAACGTCTTCATGAAATCTCTCCAAGCAAAGTTGGATATTATGAAAATGGAGAAAAGCCCAATTTCAGCAGTGTAAGATAAATTATCGAAAAATCAATAAAAATCCCAACTTTCAGACCCCGGCAATTCTAACACGTCCGCCGGCAGCAGGGTGCTGAGCCCGCTGACGCAGCGAAATGCGAAAAGTGAAGATTAGCTACGCGAACCGTCGGCGCTGGCGAGACCTTGAATTCGAAAGACCCACACCGAAGCGGCGGTAATTTGAAATTTTCACATTAAAAAAAAATCGCGAATTTCAGCACTTCCTCAATGAATTTGCTAGCAAGCACGCTTGCGGCTGAAAATCGTTATGAACTCGATCGATTGGGCTGAAAAGGACGACCGCTGCAGTTTTGCTAGAGATGATCGTGAAAAAGCCTCTGCAGCTTCAAAAATCCGTGAAAAATCGATAAAATTTCGTTTTTGTTCCGTGACATTCCAGGTGTTTTAGTCCAAAAGCAGCCTACGGATTTGCTTCCCTCATAAATTGTAATGGAAGAGTTGCCGAACTCCAAGCCACATCTGGGGTAGATTTACCGCGCGTTGCGCCTCTTTAGTTGTAAAACCAAATGTATTTCTCCGTGTGAGGTACACCACTTTCCCATTGCCCGGCGGGTGATTTTCAATGGAGCGCGAAAAATGCAATTAGGAAGCTCAGAAACCCGTGACAAAAGTGTCACGCGGGTTTCAAAGTAGAGGTGCAAGTTCGCGCTGCACCGCTCCACGGTGCTTGGCGGCAAAACCAGAATTCGCTGATTTCAAGCATTTTCCGTCGTTTTTCATGATTTATCATGTCGAAATAGTGTTTGAAATATGTCTTTAATGCTGGGAAAAGTGAATATTAAAAATTTTGACACGTTGAAAAACTGAAAAAATTATCGGAAAAGTGTATTTTGTGAGTTTTTACTTAATTTTCTCGGGGTTTTTAAAAAAATTATTTCTACATAAAAATTGATGAAAACAGCATATGAAGTGCAAAAAATAAAGAAGACTTACATAAATTTTGACAAAAATAGATCACGAAAAACAATAAAAAAAGTCGAAAAATGATTGGAAACGGAGAATTTTTCCATTTTTATGTAGAAATTTTGAATTTTTTAACAAAATTTTCTCAATTTTGAAACACAAAACATGATTTTAAAAATTATTGAAGATATACTCTTGAATTTTTAGTTGCGCCAATAACGGGACTCACGGAGTGACCATGGAGCGCTTGCATCTCGATTTTAAAATTGGTATGAATTTTTCGCGCTCCATAGACACACCTGCCTATAGGACAACGGGTAAGTGTCGTGTACTCCACCCGGACAAATATTTAACTAGAATCGAGCCGCGACGCGACACGCAACGCGCCGTAAGTCTACTGAGCCAAAATGGCCTAGTTCGGGAAAAACTCTTCCATATTCATGAGGGAAGCCAGAAACCCGTGTTTCTAGAAAATCAAGAATTTCTTTGGGAAAAAATGCCAACAATCCCAGACCTAATTCTCAGGGCTAATTTTTCCCCGAAACAGACAACAGACCCTTGTCTCCCTGTTACAAAATCATTCAAAGATGCTCCTGCGATTTCCGAACGTCAGCTGTTGAGCAAAAGGTGGTCCGATGTGTGATAAATGTAATTTTTCGAAAAAAAAATTTATCGAAATTTGCAGTCACGAACGCGAGTGTCTTCTTCAACACGGGATCCGCTGGAACCGGAAAATCTGTAATTCTCCGGAGTATCATTAAAATGTCCCGCCACATATCACCGCAGCGACAAGGTAGGGGATCACTTTGAAATATTTGCAAAAAATTTCTCGTATCAAGACCTCAAAAAATTTTCATGTACCTTTCAAAAATAGAACGACCTTTTTTAATTAAAAAATCATTCAAAAAGGAAAATTTGGGAAAAAAAATCATTAATTCTTTAATTAATAATTGTTTATTTGTCACAAGAAATAGCTACACCGGAAGATAAAGAAAAAAAGTAAATAAAAAAGATGTGTGGACAAATAAGTAAATGTCCAATTGGACCAGCTTTAGCCCGGGAGGTTAAGTTGGGGGGAAGAGGGTGTCAAATGGGATGGAGTCTAGGCGCGACGCAAATGCATTTGGAGTTAACAGTATAGGGAATGAAACGTTTTGCTATTCGATTCCACAACGACAAGTTAACATGTAGAAAACATTTAGACGGAACACCACAGACAACAAGTAGATAGGGGTGAGGAGTAGAGCGTGAAGCTCGAACGAACGATATAAGGTCGGGAAGTAATACTCACTTGAAATAATATTTTTATGGAAGGTTCGGAAGATTTGAAGAACCCGTCTATGGTGGGTGGACAATAAATTAAATTGGGAAAGCCTACTACCGTATGACGAGTAAGATAAATTGCACCTTTGAAAGACACACATTGAGAAAAACCGGAGGGGAGATTCTAGTTATTTCGTGCGGCAAGTTCGGTAGAGTTGGGAAGCGGGAAGAGCTCGCAGCGATATTCGAGTACAGGGCGGTGCTTATGTAAACATTGAACAGTTAAAATAGAATTCGGGACTTTCCTCAGAGCGGAATGAACGATGGAGTTGGCACTTAACCACGGAGTATTAGAAACCAGTCTGATTAATATGATTAACAAAAAATTTGGTATCGACAATGACTATGCTTCCAAGATCTCTGATAGATAAATCACGCGGTTTAATTTCCACCCGATTTAAACAGTATTTATGACGCCCGGGGGTTCTTTTTTCCGAAATGTAATACGGCGGTTTTGTGCTCAGCAAGATGACGCCATTTTTTACACAAATCAGCGACTTGATGCTTGTTTGGATAGAGGTATCAGGGGGTCCGCTCCGAGTAATTTTAGATCGTCGGCAAAGGCTGTAACATGGACATCAGGAGGGAACAAATCGCTCTAATAACCCATTAATATACAAAAGAAAGCGGAATGGTAAAAGAAAAAACCGTAAAAAATCAGCAAATTTCGAAAAAAAATCGTAAAAAATTGAGACCTTTGGAAATAAAAATCTAGCAAAATTTGAAAAAAAAATAGTTTAAGATTCAGAAATTTATTTTAAAAAATCATTAAGAATTCAGCAAAAAAATAAAACAAATAAATCTGTAAAATTAAAAAAATAACCAGTAGAATTTCAAAAAAAATTGTTTATTCAGCAAATCGTCTTCTAAAAAAAAATCATAATAAAATGATAAAAATTAAAAACGTAAAAAAATTTAAAATCTGCAAAATTTGAAAAAAATCGTTTAAAATTCAGCAAATTTCGAAAAAAAAAGCATTAAAAAAGCGAGAAATGGGAAAAGCACAATTTTTTAAAATTTATTGAAAAAAATTAAAAATTCATGGAAAAACCTGCAAAATTATTTTTTAAAAACCGGTAAAAATTCAGCAATGGAAAAAAATCTTTTAAGAAAATCAGCAAATTTCGAAAAAATAAAACATTAAAAATACAAAATTAAAACTTTTAGAACATCATTAAAATAATAGCCAAACCGTAAAAAATCAACAAATTTCGGAAAAACTTTACGTGTTCGTTAAAACTCCAGCAAACGTCTAAAAAAAAGCATTTAAAAAGGAGATACAAGAAACATCAAAAATCGAGACAATTGGAAAAAAAATTCGTTAAAAATTAACCCAAATATTTGCTGAATTTTTTAGATTTCTTTTTTTTAAACTAAATTTGCTGAATTTTTTAAAAAGACAATTCAGCAAAACTTAATACAACTAAAAAATTCAGCAAATTTCTTTTTTAAAAATCGTTAATAATTGCATCGGGAAAACTTGGAAAAATTGTGCAAAATTCAGAACAAAAATTTCAAAATTTTCCCAATTTTTATTAATTATTTAGTTTTCAGAATTGATTAATAGTGAAAAATTCATAAAAAATTCAACAAAATTTAGAATTCAAAATTTCATTTTCATGGGTCCCGCCACGATCCACTCCAACCTACAAAAAATCATGTAATTTCCAGGCGTTGCGGCATCCCAAATCGGCGGAATCACACTTCACGCGTTTTGCGGTTTTCGCTACGAACATTCGACGCCGTAAGCAGTGCCGAAAACATGTTGTTACGCCAAAATCACATGGTCCGACAGTGGAAACAATGCTCACACTTGATATGACGGATTTCATACCATGATTGATCGCTTTGCAGGTTTGAAGCTCTCGAATATGTGAGCTCATTGCGTTTTGATCTACAAAAAATGCGAGAGTTTTCGCAGCATTGCTCATTTGATCTACAGAAAATGGGGGAATTTCGTACTACCAGTATTGCTCCTTTGATCTACAAAAAATGCGGGAATTTTCCCAGCATTCCTCCTTTGATCTACAAAAAATGCGGGAATTCTCCATTGCACATTTGATCTACAAAACATGCGGGAATATTTCAAGTGTGACGTCAGCGCACTCATGCGAAATCTGCATGAAAAGTCTGCGTCTCTTCTCCATTTTTCGGAGCTCAAACCAAAATGGGCGGTACCCGAAAATTCCAAAAAAAAAACGATAATTTCCCGTCCCATGTCGCCCGTACGTCCGTAATAACGATAAGCCGTTCGGTAGAATTCAGCTCATTAGGTTCACTGGAGATTTCTTTCAATTACCGCCGTCTCGAAAGATGAACCAGTCTTTTGTTTTGAGGTGTGCGGAATTTCGGAGCATTTGGACCGTCTAACTATTAAAAAAATTATTTTGCAGAGCGCAGCCTGGAGCCGATGTATCCAAAAAACGATTGTCCTGAAAAATGTGAAACGACATAATGACAATGTTTTTGTAAATAATAACGTTAGAGTTGGAAAGTACGTAAACTACTGGATAAATTTAAAAATTTCGAATTTTTCAGGGTTTTTTAGTACTGGAAATATTGATTTTTCAGTGAAATTCCAATAAAAGCTGGAAATTTTCCACAGAAAAAGGGAAATGAAAATATGAAAATTTGTAATTAATTTCGAAAAATGCAGAAAATCCCAAAGCCTTCCAGAAAAGCTGGAAATTTCATAAAAATTTCGGAAAATCTGAAATTTTCAGAAAATACAAAAAAAGCAAAAAATCTCGAAAACCTTCCAGATAAGCTGGAAAATTTTAGAAATTTCCAAAAAAATAAATTACTACTGAAAGTTTCATAAAATTCACTGATTTCTGTCTTCCTTCTTGTAATGGATGAGTTTTGCCGAATCAACTAGGCCATTTGGTTCGGCCAGATGTAGATTTACCGGTTTGCGCGTTGCGTGTCGCGTCGCGAGCTCGATTACTTAGTTGTAGATAAAATGTATTAGTCAGTGTGGAGTACACGACACTTTCCCATGTGTTGTCCGGCAGGTGATTGTCAATGGAGCGCAAAAAATTCAACGAGTCCAGAACCCCGTGATAGAGCGGCCAACACGGGGTTCTGGCTTTCCTCATTTCATATTTCGCGCTCCATTGACAATCACCTGCCGGATAACACGGTGGAGTGTCGTGTACTCCACACGGACAAATACCTTTATTTAGAACTACTAATTGAGCCGCGACGCGACACGCTACGCGCCGGAAACCTACCAGAAATGGAGATGCTAGTTCGGCAAAAACTCTTACCATTTCAACTCTTTATGAGGGAAGCCAGAAATCCGTGTGATTCCAAAAAGAAGCTCCAAAAAAAAATTCCAAAAAAATCTCCATAGCCTTCCAGAACCGCTGGAAATTTCAGTCCCCTAAAATTGATAAAAATTCGAATAAATTCTCAAAATTGTTAGAAAATCAGTGAAAATTTGGAAAATTCGGAAATTAAACAATTTTTTTTGGAATTTAAAATTTAGAATTCTTCGTACGAAAGATGCTCCAGAAAACTTGTAAAAATTTAATTTTTTTTTTGAAATTTCCAAAAAATTTATTTATTTTCAGATGCGGCTTCAAATCAGCTGATATTCTAAAGTAATCCTCGAAAAATCAATTCCTGAGCCATCCAGCGTAATTCCAAACAAACTGTGCACCAGATGACGCCGATCGAATTAACAGCTCAAGCATCGAGACAACACAAGCGCGAAAACCTTGCAGAGCGCCTACGATGACGAGAGTGACGCACGCCAAGGTCCGTACGTTGCAGCACAGAAGAACCTTGTAGGCTGAAAGTTGGAGCTCAGGTGATGCTCATCAAGAATATCGATGTGAGGGACTTTGTAATGGGTCACGTGGATCTATGGTGAAATTTTCTGTGAAAACGGGAATCTCTATGATCCGATTTGTATCGCAAGCCGATGCTTCCATTGAGGCACGTTTCACAGAAATGACCATTTTATGGGCGTGGCTTTCTTTTTCGAAAATTTATTTTTTCCAAAATTTCTACATGGATTTTTCTCTACAATGGAAAAAACCCCCGAAATATTGTAAAAAATTTGAAATTTATCGGAAAAAAATAAAATTTTCTCTCTTACAATTAGGCTTAGGCTTAAGCTTCTAGGCCTGGGCTTAGTCTTAGGTTTATGCTTAAATTTGAAAAAAAAAATTCTTGCAATTTTTTCCAGATTTTTCCGTTTTTTTTTTCACAGAAAATCTAAGATTTTCGATTTCTACTTTCAAAAAAAATGAGTTAAAAAAAATTACGCAAATTTTGTAGAAATTTTTCTTTTTTTTTTCTTAAAAATTAGGCTTAGGAAGCTTAGGCTTATGCTTAGGCTTAGGCTTTGGCTAATCGCAGGACTATGCTTTGGGTTAGAAGACTTGCGCAGACAAGCCTAATCCTAAGCCTAACCCTCTTAAAAAGTTACAAGACGGTTTTTCCTTGCGCTGGGAGCTCAAAAGAAGAAAAGAAAAAGAGCTATTCGGACTTAGTGTGCCTATCTGTAATAAAACATTGGAAATCCCTATGACGCACTTAAGCCTACGGCCCGCAAAACATACTAGGATGCCCAACTGGAATAAAATATTAGAAATCCTTATGACACACCGGCGGTATGGCGCGGACTTAAGCCTAAATGGCCACTTTTATCAAAATACATTTGAGCTCGTCTTGTGTTTTACGTTGACTCCTCTGAGGCAACTCAAAAATATTCTGTGGATATTCTGCAGAAATCAGTTTAAATGAAGACAAGAGATTACTAAGAAACTTGGAGATTTCATAATATTTGGGGGGATGCGAGCATCCATTGGAAATTTGCCATTTGATACTTTTAGAGGCAAAAGTCCAAGTCGTAACAAGCTCACAGTGGGCTCTCAAATCATCAAATTGTAACGAAGAAACGATCGATATAACGAAACAATTTTACAAAGTCACTTTGGTAGCTCATATCTCCGTGGATAAAATTTTTACAGACGTAAAAGTCATCAACTGATATGTTGTTGATATGGTTGTAAAGAACAAGTTTGTTTGAAAAGTTTTTTTTACCAAAAAATTTTCGTCGTGTTTCAAAGAAATAGTAACGGAATAGCATCATAAAAATAACAACAGCAGTTGCGCCGCGCACTTCACGCGGTTATTCTTAAACGGGAGATGAGCTACCAGAGTGAAATTGGATGGCCCTCCAATGCTTCGTTAAAGTTCACGGCCATTTTCAGGATCTTTGAGAGCCCGCCGTGAGCTTGGTTTTCGAGGAGTTATATAAATTGACCCCTCCAGATTAAAGGAGGACTTTTATATAATCACGATGGTATTTAATTCCGATGAGTAATCCATTTTTCTTTTCACATTTGTCAAACAAAACTAAGTTTTAAATTAAGGCGGGATATACTAAGGTGTGATAACATATGTTATTCATGTTTAAGTTTAAATAAAGTTTTTTTTTAATTTTTGCTAAAAAACGAATTACAACCGCCTCGCTCAAATGTATTTTATAAAAGTGGCTATTTAGGCTTAAGCCGCGCCATACCGCCGGTGTGTCATGAGGATTTCCAATATTTTATTCCAGTTGGGCATCCTAGTATGTTTTTCGGGCCTTAAGGCTTAAATGTCATAAGGATTTCCAATATTTTATAGTTGGGCATCCTAGTTTTTTTTTTTCAGGCCCTTAGCCGTAAGTGTGTCATAAGGATTTCCAATGTTTTATTCCAGTAGGGCACCCTAAGTATAAATAGCTCTAGGGCTTTTCTTTACTTTTGCGCCTCCAAGCGCAAGGAAAAACCTTCATGTAAAAGCTTTTTAAGAGGGTTTCATCATTATATTTATTGAAATCGGGGCGAAGCCCTGATTTTGAATCCATATTTTTGTCTTTGTCTTCCACTTGATCCCTGCAAACTAGGAAAGAGAATGTTTTCTTTCTGATGAAGTAAAAATCATCATAAAATCTTGAAAACGAGCAGGAGGTAATATTTGAATATATTGGGTTGTAAATGTGTGTCTCCCCTTGTGGGTGGGGTGGCGATGTGCTGGCAGCCAATCTGCCTTCAACGTGTATCTCCCGCCTGTATCGCCCTTCAAAGTGAGAATTGGGTTACCAAAATTTGAGGGAATCTGATGAGAAAAGGTGAGGATTTCAAAAATATTATTGTTGACACACCAGACCAAACTTTAGCCTGGGCGAAGAGACAGAAAATTAGGAATTTTTTGAAAACTTTCAAACTGGCACAAAATTATTTCACAAACAAAACTCTTTTCACATATTGTTAAAACAGATGCCATTTTCCAATAATCAATATTGTCCATTGAACACAGAAAAGAAAACGAAGATTCTATCAAAAAATGAGTGAAAAATCGCAATTTAAAAATCGAAAAAATCCGTGCTGAACTCGAGTTTTGGCGGTGCTGAAAAGAAAATTTTCACTAAAATTTTTTGGAAACTTAGTTTTTCGGATTTAGCGTCAAATTTTGAATCTATACAAAAAAAAAATTTTGAACTCAGATTGAGTGGATAATAAACGCTCAAAGTTGAAAATTGACAACGCAAAAACGGCGTGAGTAACTTGCTTCAAGGTCGGCTGTCTCAGTGAGTTTTCACCCAATTTTCCCCAAATTTTTTTGCTCTATCGCTTTAGAAATATTTTCTTTGTGGTAATTATGTTTTCCTCAAAATCAAGATAATATCTTAAACGACCGCCATCCTATTTTACAAGAAAAAAAAAGTCTTTGGAAGAAAAATCAGAAATTTTCGGCGTCGATTTTCAAAATGACAAAATCACTTTTTCGTAATAAACTTATTTAAATGTATTTTGATAAAAGTGGGTATTTAGGCTTAAGCCGCGCCATACCGCCGGTGTGGGGGTCATAAGGACCACTATTTTATTCCGATGGAGTTGGGCATCCTTGTATGTTTTTCGGGCCTTTAGGCTTAAGTGTGTTATAAGGATTTCCACGATATTTTATTCCAGTGGGGCATCCTAGTTTTTTTTTCGGGCCCTAAGAGCGGCTGTGTCATAAGGATTTCCAATGTTTTATTCCAGTTGGGCACCCTAAGTCTGGGTGAATAGCTTTTCATTTCTTTTGGTCGCCCTCCAAGCGCAAGGAAAAACCTTCTTGCTTAACGATTTTTTAAGAGCGTTAGGCTTATGCTTAAGCTTAGAGTTAGGGTTGGGGTTAGGCGTAGGCGTAGGCTTACGTTTACGGCTTCGGCTTCAGGAATATTTAAAACAAAAATCGAAAAATAGATTTTGGGAAAAAAAATCGTGATAAAGCCTGCTAAAATTTTCACAAAAATTAAATTTTTCAAATTTTTCAAATTCCTAAGTGATTTTGGTCTCGCAGCGAAAAAACATCCAACTACAGTAACCCTCGCCCTCTCCAATTTTCAGCTCCCCGGCTCCAATGTTCTCGCATTCCAGGGTGTGATACTCCGTTGATTCGCCGTGAACTCCCACTCCAACTCGCCTGGGCCATCTCCATTCACAAATCGCAGGGAAGCTCGACAGTCCGGGAATGTTGAAGCGCGTTTTCGCCGACGGACAGGCGTATGTGGCGTTGTCGCACTCAAGATCAATGGACGGCGGCAATTAATTATCGGCTTCGAGCGTTGTGTCCGAGCGAATTCAAAGGTGAACAGGGGATTTTCGAGATGAAATCTATGATTGCAAATCAGAATGGATGGATGCTGTTAGATATCTCCTTTTCGTGGGTTCTCTCACGTGGTAGAGTGCTCATTTCGGCTCTACTGTGTAGATCTACAAAAAATGCGGGAGATGAGGAGACTCAGACTTCTCAACTGGTTTCGCATGGTCTAGAACGGCGTTGCTGACGTCACTTTTCTCTCGGCATAAAATTCCCGCATTTAACCGGTAAGGGATCTCTCAGCTACGTGGAAAATTATCGATGTTTTACCGAATTTCAGGTTATCTAGCTTTTTACAAATCCATCGAGGCAGAATGCGACGACGAACAGGACTGGGGAGCCCCTGGTGCTGGGCCTAGTGCTCAAGTCGAGTTCGATCGATTTTTTATTTAAAATTTTTTTGTGATCTCCAAATGTTTCTGTCTTTCTATCTTCCCCCCCACCCCACCAAAATAACCGTTTTCACAACACTCTGTATCATCATAATTCTCACATAAACTATTTCAACGTTGACGTCGCCTCAATTTTTAGTGCTATAAGCGTCATCGGATCTGAAAAAAATGTAAAACTTGAACAAAAAAGCAGGGGGTGGCCTAGAAAGCACAAAAAAAACTCGGACACAGTTCAGGAGCCAGTTTTTGGAAAAAAAAAAACGTCATTTTCGTATAGCCGTCCACACTGAAATTGAAAGAATTCTGGCCGAGTTTTCCAAATTCTAGGCCACCATGCAAACCGACGTTTTGGACGGCAACGTGCCGGTGGCCGTGGCCCCAAAGAAGGAGGGAAAAACTCGGCCACTCTTCTATGTACCCCTCTCGGGGAATTTTTACCATGGCCGAGTTTTTGTGTCTTCTAGGTCAGGCATTTTTCTTAGTCAGTTTCAAAGGAAATACGATACCTGGTCTCGACGCGAAAATTTAATTAAATCCAAAAAGACGTGCGACTTTAAAAAGTACTGTAATTCCAATATACTTGCGCTGTTGGGAAATTTATCGATTTTTCGTATTTTTCAAAAAAAATAATCAAATGTACACAGGGTTCTGTTCTTCCTTAAATTTGATTTATTCGCGCTCCATTGACAATCGCCCGCAGGATAACGCGTGGGAAAATCGTGTACTCCACACGGACATCGACGCGACGCGACACGCAAGTCGCGCCTTGAATCTACCCCAAATATGGCCGAGCCATAAAGGCCTATTCGGCAAACTCTTCCATATCGATTTATGAGGGAAACCAGAAATCCGTGAGGATAGTGAGAAAACAACGAAAAAATCATAAAATTTCCCAACAAGACGAAAGTTGAGATTACAGTAGTCTTTAAAGGCGCACTTTCTCGCATTTAACTTAAATTGGTCGTGGAGAGAGTATTTTTAGCGCAAAACTTCGCATTCCGGGTAGATAATAGAAGAATTGAAACTGACAAATCCGCCGTTTCCTCAAGCAGCAGCGGCACAATAAACATGAAATACACGGCCAACACGAAATGAAGCGGCACCATCGACACAATGAACAACGACATTCGGAGCATGTGCTACAAAACTGTCGGCCGCAACTTTTTCGACGGATTCTTCCCAAAGACGAGATACCCTTGCATCGGGCTACATCGGGGCTTGAACCGACTTCTTCTTCATTACAGCGCTCCCTTCTCTGGGCAGCAGGTAGCGTGTCCACGTGGTATAGGGTGACTCAGTGGTTCTGTGATTAATCGGCGCGAGCTGGAGCATTCTTTGCAGAGTCGCTAGGCGTGAGGCCACGGTAGCGGAGGTGTTGGCTCTGAAAGTAGATTTCATACAGGATGGTTATTTCGGGGAGTACTGTAGTGGTGTTATAGTGGTTACTTGTAGGAGTACCCTGTAGGGGATACGAAATGCAGGGGTAGCAGTACTGAGGGGGGTACTGTAGGAGTACTGTAAGGGTGTGGGGGTACTGTAGGAGTAATGTGGGGGTACTGTAGGAGTACTGTAGGACCACTGTAGGGGAAATGTAAGGATGCTGTAGGAGTAATGTAGATGGTACTGTAAAGGTACTGTAGGGGTGCGCTAGTGATACTGTAGGGATCATGTAGGAGGACTAGGTCCTGAAATAAGGGTACTGTAAGGGTACTGTAGAGGGTTAGTTTTATGTCCCTGTAAGGGTACTGTAGGGGTACTGTAGGTGTACTGTAGGAGTAAAAGTGGATTCACTGTAGGACAATAACGCCAGAGGTACTGTAGGAGCACTGTAGGCGTACTGTAAGGGTACTGTAGATGTACTGATTATGTAAAAGGTCCTGTAGGGGTACTGTAAGAGCACTCTAGGGCCATTGTAGGGGTACTGTATGTACTGTAAGGCTACTGTGATGTACTGTAAGGGTACTGTAGTTGTTCTGTAAAGGATACTGTTGGAGTACTGTAGGGTTACTGTATAAGGGTACTGCAGGGGTGCTGTAGGGATACTGTAGGAGTACTGTAGTGTCTATAGGAAGACGAACTTTTTTTTGAATTTACTCATCGGAGAATCTAATATTTTCTGTCTCCAAATCGATACACCATAAAAATTTTAGGACCCAGAGCTAAAAAAAAATACCAACTTCTCCAATATCATCTCCATCAATTCCAGTTGTTCTGTGCAGTTCGCCATCCCTTCTTCATTCCATCGGCCGATTCTCCAAATCGTCCACCATCTTCACACCCCGCCGACACGCCGGTGTCTCCACATCGTTCCGTACCAGCTTCCGCAATTTTCATAAGATTCTCGACAGACTCGTTAAACTTGCGTTGGCTTGAACAAGTGGGAACCTAGAATCGCCTCGGGAACCGGATTTCCACCCCCTTCCACCAGGAGGCTGACCAGTGTCGTTTTCTGCCTGACGACCTTAGCCAGGACGTGCTCATAGTTGATCATGTAGATTTGCCCGTTTTCAGATATGTTGAATGTTTCAGATGAGGACAATTGAAAATTACCGATTTGATTGTGCGTGTTCATGCACGACAGTAATGAAGGCGAGGCGGCAAATTAAAACTCTGAAAGTTTAGATAATTGTACTTTAGTTGAAATCCTTTTGTTGACAGTCGACTAAAAAAAAAAGCAGGTAGGTAGTAGGTAGGTAGAGTAGGTAGGTAGAGTAGGTAGGTAGGTAGGTAGGTGAGTAGGTAAAGAGAGACACGGTGCATCGATCTGACTTTAAAAATCTCAATCTCGTATCTTAAGCGTCTTTGGTTCCTGTCAGGCAGGTAGGGGGGAGAGTAGGTGTGATCAGGTAGGCAGAGCTCCGGAGTTAATATCTGGTGGATTGTGAGTTGCTAATAGGTAGTGTAGACAGGCAAGCAAGCAAGCAAGCAGTCAGGAAGGTAGGTAGGTAGGTAGGCAGGCAGGTATCAGTTGTCAACTTTTTGATGAATCTAACGGAGCCGAACGAGTTATAAGGAGGCCCAACGTTGCACCAGACATCGGGAATCGACCTAACTTGCAAAACAACTCGTAACTTAAGAGTGTCTTTGGTTCAATTTGGGAGGCAGGTAGGTAGGCGCTTAAGGTAGGTAGGTATATCTTACGCTTCTTGTTTCAAAAATAGTTATATATTAAAAAACAATAAAAATTTTTTGCAAATTTTATCAGTCGACAACTTTTCTTGTTAAAACTAAAAAGAGACGAGATATTGTAAGTGTTGCAAAAGTTGAACGAGACATGGTGCATGGAAGGATGGCTAGGCAGGTAGGTAGGTATTAAGGAGGTAGGTAGGTAGGTAAGCATTCCGTATTTCTCTACTTGCTTATATCCTGGTTGTTATGTGTTGTATCAAAAAATGTTTAACAAAGATAACATAGACTGAAAATATTTAGCACGTAGCAAACTTAAAAAACTAGGTTGGTAGGTAGGTAGGTAGGTAGGTAGATAGGTAGGTAGAAATGCAGGCATGTAAATCTGGTGAAGGTAGGTAAAAGTACTCACGATGGAGAACATCAAGCAAGAAGATCGCCAATTGAAAGTGGTACGGAAGCGAGTTGAGCAAATATTTTAGAGTATTTGTCTAGAAAAAATATTAATAAGTATTCAAAGTTTAAACTAATAATAAAATACCAATTCCGAAAAACTTCATTATAAACAAAATCGTCAGAATCCCACTGGAGAGGACTAAAAGTCACTCGTGTTGGCAGACGTCTGATAAACATCGAGGGTGTGTCCGGGTGGTAGGAGAAGCACATTATCGTGATACTTTGACACTGATAGATTCCTCAATAGAAGCCAACGCTTTTCCGAAAACTGGAATCGAAATGTTCAAAGCATTGAGAATTATTTTCTGGTACTCTTCAACCAGGCATGTTGTACTCCGAGTTTAGATCCGCAGAAAAATCTAAATTTGTATTAGATTGGGCGATACCGTACTTGCCTACCTGCCTACTGGTAGGTAAGCAGCCTACTTATTTTCAACTTACAAACCTCCTACTTTGTAACGTTTATTTCGCAATAATCGATTTCTCGAAATATTTGCATTTCCCCTCGACAAATGATTTCTTTGCGGGAATCTTTAGGAACAGCTGAAAATTTTTTTTTCCGTGTGGCCTTTTCACGGCCACGACGTACCTTAACGCTTACACATGGTGCAGTTGACGTAGTCATGCAAGAACCAATTTATTCGGCGGCGTTCGTTTTCGGTGACGGCGAAGTTTAAGCACGGTATGTAGAACCTTACGGTGGAGACGTTCTTTGATGGCTGGAAGTTATGACGTCATGTATAATTAGGGATGAGATTCCTAGGCCACGTGTGACGTCACAGCAATCCCCGAAACCCTGGCTTTTTCGATGGGCGATTTTTACTACATCGATACTTTCTAGGCATTCATCGAGCGAAACTTTTGTGATACTTTGGCAATGGTCATCAGGTAGACAAACAACGTGATAATTTCTAGGCCACGCTTGCCTCTGTCACGTGGCCGAGATTTCGCGCCAGGACCTAGAACTAGACAGGGTGCATCGACCTAACTTAAACCTCGTATCTCAGTTGCCAGGTAGGTAGGCAGGCAGTCAAGCAGATAGGTAGGTAGGCTGGTATTTTAATTTCATTTCTGCGGCTACAACACAATTTCTCTTCCAATCAAGGACAAATTTCTAGCGCCACACATGCAGAGTGCGGACTAATAATTAAAGTGTTTTACGACAAGGCCGAGAAAAGAGAAACCTAGGCCACTAATTTGTAGTGAGGTGTGATGTAACGCCACTATAAAACTATAGAACTCGCTTGACGCATAAAACTCTGATCATTTGCGGTTTCGAACTTGCATCGTCCTTCCATAGACCGCATCCTGAACGTACACTCTCGTAAATTGCGGCCTAAATTGTATAGACCCATTAAAGGGTACAAAATATGGGAATAATGGTGAATCCGGAGCGATTATCATCCAAATACACGAGAGATTACTTCGATACATAACCTCGAAGAGCAACAATTTCCCCACGAAGAATATCAGCAGAGCTGTGAGCAGGAGAGGCGATTATTATCTGGCGGATTGTGCGCTGAAAGTAGGAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAAGTATCGGGTGGTAGGTAGGGAGGCAGGTATCAGCTGCCGACTTTTCGATAAATATTAGACGGAGCGCCGAAATATAAATTGCCAAAGTTGTACCAGACATGGTGCATCGACCTTACTTAAACAACTAGGTGGTCTAGGTAGGCAGGCAGAGGCAAGTAGGTAAACTCACCGAATGCCTTAAAACAATTGCTAGAACATCGGCATAACCCGAGCTTCTCCCATTCTACGTCGCGACCACAAGCGCGCGCACACTTTTCCGCAGGTTCTCATCATCGCGATCAGCGCAAAAATCCTCGATTATCTCGAATCCACTGGCTCTTTTTTGTGTGCGACGTCTAATCGTTTATAGCTGATCGGCTCGGGAAAACCAATCGTCACACTGCAGCTTCGCATCCTCCAAGCGGAAGCCGTGAGAAAACTGGGCACTGCATAGGAACTAGAAGTAATTTCAGTCTTATTGTTCTGGAAGAAGGCTTTTTTATGGATGGGGTTTGAAAATAATCACTAAAAAAAAAACTTACAGCTGGAACTTTGTTCGATAATGAAACAATTAATCTATAAAAAGCAAATTTTTGACAAAATTTAAAACTTTAACGTGTATGAAGGTCACGTGAAAACTGAAAACAAAAATGTCGAAAAATAGCAAGAAAACGGCCTAGGCACACGTAGACTTATGGTAGGCAGCAAGGCGTAGGGGTTGATCCAGGCAGGGTCACGTCTTGAAGGCAGGTTAGGTATAGGTAGGCATAGGTAGCCATATGTAGGCGTAAAGGCAGGGGCATCTCTAGATCCTTTTTGTATGTGGCAGATTGGCCGCTTTGCAGGCAGGTTGGCAGGTGTGGGTGGCCTAGTAGACCGAAGTTTAAACAAGCGTAAAGTTCCTATAGTAGTAGGTAGGCCAAACCTTTTTTGTAGATGATGAAGTAGGTGTAGGCTGTCGTTTGAAGGCAGTGATGCAGACAAGGTTAGGTCGTCGCAAAGGTTGGCTGGAGGGTAGGCACGTGGGTCAGCAGATAAGCGTAGGCAGGCATAGGCAGGAAGGCATTAGGCAGGTAGACGTAGGCAAGTAGACGTAGACAGGATTTCAAATATGACGTGAAAAGGGGAAAATTTCTTATTCTGCGAGGCGATCCAGTATGCATAGGCAGTTATGGCGTTGGCCGGTAGGCGTTAGGTAGGCGTATGTAGGTAGGCGTCGATGTAGCAGGTAGGCGTAGTCAGGTCCTAGAGATAAGCAGGTAGTCGTGACCGGATAGGCAGGCAGGTAGGCGCATGCAGATAGTCCTAGGCAGGTGGGCGTAGGAACGTAGGCGTTGGCAGGTAGGTGAGGTAGGCGCAGGCAGAGACGTAAGCAGGTAGGCGTAGGCAGGTAGGCGTAGGTAGCTAGGCGAAGGCACGTAGGCGCAGGTAGGCAGGCATAGGTAGGTAGGAGTAGGCGATGCGCACATGAAAACCTTATAAATGTTTCAACCGCATAATCATCATCCCATTTTTCTCTCGATCAAAACGAAAAAATGCCAGCAGCAAACACAATTTGCATCCATTTCTCTCTCTTACTCACTTATATATCCTCACTTTATCCCCCGTTATTCAACCTTCCAAACACTTCCAAAACCTCCAGAACTGCTAGAGAGTAACACGGAAAATATTTGAACTTTTGTCTCGACCAAGTTTTTTTTTATTTTTTCTTTGGATTTCAACAAATTTGATGTCTGTATTTTTTCCATTTTTCGTGCAAAATACGGTAATGAACTAGGTTTTTGCTACGTGGCCTAGAAAATCTCGGCCACCGATTCTGATCTGTTGCAGGCGGCGGCCGCGGCCGAGGGTTTTTCACTTCAATTGATACCAATCCCTCTTTTACGCAAGGAATCACGTGGAGTGTGTCTCTTCATCTTGATTTACGCAGATCTACAAAACATAGCGGGAACTGAGTTCGTATCGTTAAGAACATGCTGACGTCACAGTTTTTTTATCAGCGTGTAAATGTAGAAGCATTCCGGCATTTTTTGTAGATAAAACCGCAATGGGACAGCCTGGCACCACGTGCTCTTCAATGGCAACCGTTATATTTTTTTTGACAAAATCTTGAATTTTCTAGGATTTCAATGAAAATCCAATTTTATACCAAAACTTAAAAAAAAAATGCTAAATTCGACTAGCAAAAAATGCACCCAGTTTTACAAAAAATCTTTATTTCTGAAAAAAAATTCAGTGGAAAATGTCTATAATATTCAGTATTTCATACTACGGAAAACAATTTTTACAACAAGTTTTGATGTGGCCGCGGCCGAGGTTTGCTTTTCCACGTGGTGTCAGACTGTCGTCTCTCGGCTTGATCTTAGATCTAAAAAAAACGCGGAAACTGATTCCTCATGCTATGTTAAGAACGCGCTGACGTCACATTTTTTTGATCGGAAAATTCCCGCATTTTTTGAGCGTTTGAAACCGTGATGGGACAGCCTGGCATTACGTGAAAACAAACAATGCAAGCGCGCTCAAATGTAGTCGAATATATTTGCTCTACCACCAGATAAATTCCACTTTTTCACAATAAACCTAAATATTTTTTGTGTCAAAATCTTGAGAATTCTTAGCATTCGAGAATTTCCGCGTAAACCTACGATTTTGTTATTGTTCAGGGGAACAAGTGAGCCACAAAGCTTCCACTGCTGCTCCGAATTCGATTCCCCTGAGGCATTTTTGTTCGAAAAAACCCTCGTTTGTCATACTCGTCGACTTTCTTCGAAGTTTTTGTTCTAGTTTCAAATAATTTTTCGTCAATACTTGTTCCTTCCGACCCAGCAGATGTTGTTGGGGGGGGGGGATGGGAGAAAAAAAATAAGAGAAGAAGCAGAAACTCGACACTTTTGTGTCCGCATTTCTCGTAAAGTAGATTTTTGAGCTTTCCAAGGCTCAACCACCTAGCAAATTTCGCCGCAGAGTTGATTTCTCCGGGATAGCGTGGGCTTTCTACTGGAGACCTCACTATTTTTTTGCCTTTTAGTAGAGCTTGTTAATCTTTTTTAATAATTTATTGCAGCTCTATGGATTTTCCAAAAAAAACCACCCAAAAGCCCGAAATAATCAAAATTTTCGTTTTTAAAACGCTAAATCCCGTACGACATGCCGTCCAAAGAACACTCACATAACAATGAAGAGATTTCGCCAAAAAAGTGAAATCCAATTCAATTTATTTCAATTTTGAAGAGTGCGTTCGTCTTTTTTCGACAAAAAAATAAGAAAATGTGTACCTTGTGTAGTTTTCAACAGATTTATTGTTTTATTAATTATATAATAGAAATCAAACCTTCTTTCTGCCGACCTGTAGATGGCTACCTACATGCCTAGTTGCAAGTAAGGAGACCTGTGTATCTATCTAGGTACTTATCTCACACCACCTACATACCTACTACTCACCTCCCTACTCATGTAGACATAAGTGATCCTCAAAAAGGAATGCGGTAGATCAAAAGTTTATGGAAATTTATTTCGATTTTCAGGTTTTTAAAATTGCGGAAGATGTTTTCATTTAGATTGAAGATTAGTTTAAATTTTTTTTTAATTCCGTAAGAAAAAAAAATTATTAGTTTATTATTACTCTTTCTATTCCGAATATCTATGTGAAGCTCTTTTTAATTCCTTGGTTTTATATCTAATCTTAAAATCGCTAATTTCTTGTGCACCCAAGAGATTTCGAATTTTCACGGGGTTCTAGCCTTCCTCCTTGAATTTTTCGCGAGTCGCTCCATATAATAGAGAACCGGGCAACGAGTGGGAAAGTCGTGTACTCCACACGGACAAATACATTTAGTTTACAACTGAAACCGAGCCGCAAACACGCAACGTAAATCTACCTCAGATATGGCCGTGCTAAAATGGCCTAGTTCGGCCAAACTTCCATTTCAATTTATGAAGCCCAGAAATACCGTGTAATTTTTGCGCCATCAGAGACGCCATGTGTCGATTTACGAGATTGTTGTATATTTACAATCGGGAATGCGTAATATTTACTAGAATGCGGATTTCCGTTTTTTTTTTATGAAAAACGTCATCCACAAATTAAATTCGGCGATTTTAAAAATCGCGTTAAATATAAAATCAGGGAAATTTTTTAAAATTTTTTCACGTAGGATATCGGAATACAGGGGAAAATTTGGAGGCAAAAACTAATGTCACCCTGATCATGTTTAAATTCTTTAAACTATTGATGAGAATCCTTTTTTCCTAAAATGAAATAATTTCTGACTTTTTTCTCTTTTCAATAAGAAGCTAAAAACAGACGAACCTATTCCAATTTCCCACCACACCAATTCATTCTTTCCGCATTCTTCTTCTTCCATTATTTATCTACCTTTTCCTGCATTCTCTGTGCTCTTATAAATAGTTCCATCATCCCATTTGCTTTCTTGTTGTGTGGTATGCACTTTTTCAGGTCCATAACCTATACGAAAATTCGATTTCATTTTCCATTCTCAATTACATTTTAAAAATTTTTTAAAGCAAATCTCGCCCTGAGTCCATCGATTTTAAAATACGTTTTTTGGTTTTCAAGAAATTCCATTATGAAATTCGGTGTCTTTCAGACAATTTTGAGCCTAATTAAACAATTTAAACTTTTGACTACATCACCTTAAACTTAATGCCGTTTAAACTTATAACTTTTTCAGAATCCCATATGCTATGGAAGTATTGCACTTGCTACACCGGCTAATTCTCATGATCCTGGTCCTAATCCCATGTTTCTGGCAAGCTTACGATTATCCCCGTTCTCGATTCTCCGATTCTCTGATCTATCAAGAAATTCCGCGCAAAAGAGCTGATGATTTCAAGGGAGTTTTATGTGTGCTATAGCTTACTGACAGGATTTCAAAAAACAGTTACGGTAAGATAGTTTTTTCGAAAAATTCTTTCACGGATTTCTTGCTTCTTGCCGAACTAGGCCATTTTGGTTCGGCCATATCTGGGGTAGATTTACGGCGCGTCGCGTGTGGCATCGCGGCTCGATTTTATTAGTAACTAAACTAAAGGGATTTGTCCGTGTGGAGTACACGACTTTCCCACGCGTTGTCCGGCAGGCGATTGTCAATCATGGGGAGCGCGAAAAATTAAATGAGGAAGGCCAGAACCCCGTGCCTGTATAGGATATTTTGAATCTCGAATTTTAACGAAGATTTGATTGTTTGAGTTTGAGGTCGGAAAATAAAAAATTCCTTTACGGTAAATTTTCGGATGCAAAAATGTGATTCTGCTGTAAAAAATCCGAGAAAGCCAAGAAATGTGCGGAGCCTATTTTCCGATTTTATATTACGTGGTTGGTATTTCAAAACTTCAAAAATATCAAATTCGGAAAAAAAACCGCTACTTGGTAAAATTTCCTCGTAAAATATTCTCCGCTTACGCCGCCCCTCTCTGGGCATTTGGAAATTTTTTCGTTAAATTTGTTGGAATCTGAAATTAAGTCCAAAAAGAACCAAGAAACGGGCGGTATTATGGGATTGAGACATGGTGCATCGATATGGAAACGGCTTTTCTCAATTTGGTTTTTTTAAGGATAAGAAACTAGCAAAACTCAAGTGGCCTAGCTTTCAACTCTTCCAGAATTCCATGATACATTCAAACTGGTCATTGCTCATTGACGCTCTCTCTTTATGTCATCACCATAACGAATCCACTCAATTTTCACTCAAGCTGTCATCTCCAGCAGTGTCTCTCAATTTAATCATGCTTGAAATTGTTTTTATAAAATGAAACAACAGCGACATACTCTGTAAAAGCTATTATTAAAAAGTATATATATACACGAATTCCTGGGTGGGGATTGAGACAACGGAAGACATGGAGGAGAATTTGAATTTCATTAAAAAAAAAAGACAAAGAGGTAGGTTACTGTAGCATCCAATCTGGAAGTGGCTGCACAAAGAAGAACCTCCACCGTCAGCAATATGTTCGACACACCTGGAACGTTGAAACGGGGTATTATTTCCTTAAAATTTTCTTAGTCTAAGCCTGAGCCTAAGCCTGAGCCTAAGCCTAAGTCTAAGCCTAAGCCTAAGACTAAGGCTACCTGAACCTAACCCTAGGCCTAATCCTAAGAAAAATCCTAAGCTTGAGCCTAAGCCTAAGCCTACTAAAGCCAAAACCTAAGCCTAAGCCATAAGCCTAAAGAGCTCCCAAACCTTAGCAAAACCTAAGCCGAGCTTAAACCTGAGCCGATACCTCCTAAGCTTCCCTATGCCTATTCCTAAGCCTAAATATAAACCTAACCTAAGCCTAAGCCTACGCCAAGCGCGTCAGAGCCTAAGCTGAGCCTGAGCCTAAAATTAAGCCTCAGCCTGAGCTTGATCTTAAGCTTAAACCTAAGCCCTGAAAATTTTTTTTTGAACTCTCGCACAACAAAATTTGTAGAATGTTATGAATTTAAAAATTGAGATTCTAAAATTCCCCGCCAAAACGTTTAAAAACTTCACATAATTTATCTGTTTAAAATCTATATCCATCAACGGCCATACCTCTTAGATTTAGATTTTCGCGGCAAAACTTGTAGATCATTTCAAAAATTTACTTTCGCGCCAAAGATTGTTCGGCTCGCGAAATTTACAATTTTATAAAAAATGTATTTCACAGAATTTCAAAAAATCGAAAATCGCGCCAAAAAATCCATTTATAAAATTTTTTAAGTATTGTGACGTCATAGACTACAAACTAACCCCTCTATTGCCCCTCACCGTGCTCTCCAATGAGTTCGGCTCCACTTCATCAATCCCTGGGAACAGGCCCGGGTCCTTTTTTTCCTCGTGGGCCTTGTGCACCAATCGGGCAGTCGATACCAGGCATATCAGACGGTCCTGGCGTGCCCGAATTCTCCTCTCTCCGATCGTACCTGCCGTTGGACCCGATGGATGAACGGTTTCGTGTGGCGTCCGCACCCGGGTCGCCCATTTCTCCATCCAGTCCTTGGCCTGAGTGCCTTGTAGGCCTTTGGGTCCCATTTTTCCTAACCATTTTCCGCGAGCCGAAGTCCATTCTTTCCGGTAGTCCTGGCTTACCAGTGCTTACCCTTTCACTCCCTGAAAATTTAGTTTGGGGTATAGGCCTATCAAATAGGCTTACCGTAATCCCAGTGGTTTGTACTTCTCTCGGACACCGGATCCGCACACAAAGACTTATAATTCACAGGAGGCCCACATGGCAGGCGCGCTGGAAGTCCAGGCGCACCTTCCGATCCTCTCGTTCCAGGAAGACCGTCTCTTCCTGGGATCCCGGGGGGCTGTTCCTTGTGGATGACGGCACTCACATACTCGGTGGATCTTGCGGTTTGGCCGGTTTAGGAAATCGTCCATTTCATCTCTTTTCTGGCGGGTTATGTTTTGGAAATCGTTGGCGACAATCGCATGTTTTTCATCTCGAGGGCGCTCGGGTCTTTGGACATTTAAATTTGCTTGAAATTTTCAAACTTGTTATATTATAATTTACAAACTACTGACTTTGTATGTTTTTTTTTTATTACAGGAACACAAAATTCTAAGAATGCGTACTGCACAGTATATTTGACGTGCAAGATATCTCGTAGCAAAATCTACAGTGACTCTTAAAATGCGATGACTACAGTCGCGCTTGTGTCGATTTAGCTCGATTTTCGCAACTTTTTTTCTTTTGGATTTCCTTCGTCGTGTTGTTTTCTAACATCTTTTTCTTTCAAAATTTCAATAAAGCTTTCTATCGATAAATAAATCTTTTTACTTTATTTCGAAAATCGCCCGTAGATCGACTCAAGCGCTACCGAGTCATTTAAAGGTTCACTGTAGTTTTCGCTACGAGATATTTTACGCGTCAAACATGTTGATACGCATTCTCGAATTTTGTGTTTCTCTCCATCATACTGTGTTTTTTGGATTTGAATGGAAGGAAAAGCCCGAAACTTTTAAAATTTTTCGGTGCATTCGGTATCCAAAAAGCTGAATAAACTAATGTGTACAAAAAAATGCCACATTTTATTGAAAAGTTGATAATAAAATAATTTGTTCTAATTAATAATGTTTTGAATTTCTCAATTTTGGAATTTTTGGATTTTTTCGGGCCAGAAAGTAGGCATTCTCTGGAATGATGTTTTCTTCATAATTATATATTCAAAAAAACGGACTCCCACAAAAAAAGGTCCGAGAGGCGAACAAGGTTGTAAAACTTGCTATTGTTTATTTACAACCGCCATTAGACACCTATAGGGGTTGTAACAAGCCACATAACAATTTGATAAGATGCACACAGTAGGGAGAGAGGACCTGATTTAAAAATATAAGGAATTTTCTCATTAGATACAATTTTTCTCTATTTCTTTCACGGTGGAATATCGAGAGGAAAATCAGCGAAATTTGAAATTTTTGAGAGGTTTTTTTCTAAACAAAAAAAGATTTGAAAAATTTCAAGATATTCTGTGTATTTATCGATAAAATTTGAGAAATCAAGGGGGTCGTATAGTAGTGAGACGGTCGGTTTTTCTACTTTCAGCTAACTATATGAAATTTCATTTGTTCAGAGACGGTTTTCTGACATTTCAAATCAAATGGCATTAGCTGTTTTTCATGAAAAGTTTCAGAAAGTATCAAAGCTCGAAATGTTGGGAGGGTCGTATAGAAGGTGGACGCACTAAAAAAAAAGGAAGTGGTTCTAATTATTACGGAAACACCAAATTCTGAGAATGCGTATTGCAGTCAAAATATGCGCAAAACTTCTCGTAGCGAAGACTACAGTAATTCTTTAAAACTTTTGAAGCGATCGTGTCGACACGTGGTGCCGGGACAGATTGTCTCAATATTTCGGCTTGATCTACGTAGAACAAAAAATGCGGGAGAAGAGACGCAGACTTCTCAGCTTACTGATTTCTCATGGGGAACCTGCTGACGTTACATGTTTTCGGGCCGAAATTTCCCGCATCTTTTATGTGGGTAGATCAAACACACCGTGATGGGACATGGCAATATGTGTGTCGATTGTTGGGTTTTTGAAATTGATTAAAATAATTTAGTTATCGATATTATATTGAAATTAAACAAACAGTGAGAAAATAACTCGAGCACGTAAATCGACACTACAATAGTCATATAAGCTAGAATTACTGACCGTTAGCAATGCCACAAAATATGTTTGCGCGTCTAATATATTGCGCAGTACGCATTCACAGATCCGTCATCCAAGTCAAACTCCTGACAGTACTCGGCATCGTTGACATTGAATTCTGAATAGCCGAGTGTCGAAGTATTGAGGCAAGGGGTCTACGAAACAATGACGACATCGTGGATAGCGAGATAAATAGTGAATCTATGATTCACGTGGCGTGCTTTCTCGAGCATTCTCGTTCATTTTCCAGGAGAAGCAAGAGAAGCCTATGGAGAACGAAAAGTGAGTAAAGAGGAATGATGCGCTGGCGCGGAAAAACGAGAGCGTTTATGTATGGGAGTGACCCAAAGACACGGAAAAATAGATAACAAGAAGAACAAGGGGGCAACTTTCTCTATCTCAACATATCATCATCACCCATAAATCATTATCTCCTTTCTCCGGGATTTCATGAGAATAAATCCATTTACTCGTTTTTTTTGTGTCTTAAGTCTGCAATAAATATGTAGCTAATTTCAACTTTAAAATAAAACTTAATGAAACTAGTAATTCTATCATCTCTCAGCATACCCATTCCTTTCTTTTATATATAACTTTTATTCCACTCTGTATTTAAAGAAATTTCAAGTTTAGAGTCTAACTTGAAAATTGACAGTGATGAATATAAAATTATACGCGTAAAGAATATTTCGAGAGAAGTTGGGAGTGTAGTCTTGGAGGAGGAGAGAGGAAAGAGGTGAGGAAAAATTACGTTTTTTTGAAGTTTTTTCTTTAATTGTTCGAAGGATTAGGCTTAGGCTTGGGCTTAAGTTAGGCTTAGGCTTAGGAATAGGCTTAGGCTTAGGTTCAGGCTTAGACTTAGGCTCAGGCCAATTTAAGCTCAGGCTTTTGTTCAGGCTTAGGTTTAGGCTTAGGCTTAGGCTTAAGCTTATGCTTAGGAAGAAGGGTATAGGCGGCCTAGGCTTAGACGTGCACAGGCGTACATTGGCTTAGGCTTAGGCTTAGGCTTAATCATTAGGCTTAGCATTAGTGCTTAAGGCTCAGGCTGAGGCGTAGGCTTAGACCAAGGCGTAGGCTTAAGCTTAATCTAAGGCTTAGGTGTCGACTTAGGCTTTAGGCTTAGGCTTAGTCTTAGGCTTAGGTTACTCTTAGGCTTAGGATCTCAGGCTTAACGTAGGCTGCGGCCTGGGTGAGGTTTCGGCTTAGGTATAGACTTAGACTAAAGACTTAGGTTTCCTAGAATCAGACTAAGGCTTAGGGCTTAGGCTTGGGAGGCGCTACCGAGGCTGGGCGGATCAGAAAAAGAGACCAAAATTCCAGGGAAATCCAAATAAAATCCAGAGAAAATAATAAAAAAAAGGAAACAAAAAACGTGAAAAATGGGCATTCCGCGTCTTCCGCGTCAAAACCCGTTTTCCTTAAAAAACGGACAGAGGAAAGGACCAAATTATGAAATACCAAAGTTTAACAAAAAATATTTAAACATTTTTTTTGCCGGGGTTGAGCTCACCCAGCTGAGCTCACTCCATAATTGCACACAAAGTGATTCTCAAAAAATTAATTTTAGAGACTACGAGGCTAGCAAATGGAATGCACATGCTCTGATTTCTCAGAGCGGAAATGCCCGCCAGGCTCCAAAGAGCGTGTGCTCCAGGAGCCGATGGTCCTGAATCCCCGGCTCCAGAGGTCTGAATGGTATGGATGGAGAGGCTGGGCACAGTAATATGGCTGGTATGTTCACTGTAAGTTGCCCAAGATCTTTTTTGTAAATTCATACTCCAGTCATGAACAGGATGCATCCGTTGCCTAGCGGGTCCTCCAGGTTCTCGCCTGGTGATCATGGATCTCCTGGTAGGGTACCCCGGGTCAGGACCTCCAGGGGAACCCGGTTACGCAACAATTGGGCTTATCGGGCCACCTGGGAGCGACTCGCAGGCCAAGATGGTCTAGATGGAGCTCCTGGCGAGATAGCCGCAGTGGAATGGATGCAGGGGAGATTGTTTCAGTTGATGGAAAAATTGGAAGAAGAGGAGAAGCGGGGAACAAAGGAAGCAAAGGATCTCGAGGAGGGGTTGGAAAAGCTGGAGGGCCTGGGGTGGCTGGAGAAATGCGAGAAAAAGGAGTAAGAGGTGAAGATGGAAAGCCTGGAGAGTCTGGAAAGGTGAATTTTCAGAAGTTGATCGATGCACCAGGGAAATTAACGCGGTTTTGCCGATTTGGCCGGAAACTGTCAATTCCGGCAATTCGCCGGTTTGCCGATTTGTTGGATCTCAAATTTGGCGGAAATGTTTAGAGGGGTTTTTTAAAAGACGAAAACACTTAAAACTTTATCCCCTTTTTTCCCGTTTACTAGGGAATATAGTTAATAGGGGAATTGCTAGGAAGAAAATACAAACTTTAAATGACTGATGAGGTCTTCTGGCTACAAAAATCATTTTTTTCATTATTATCATTTTCATAGAATTTGCTCTCTTCAAAATAGACGTAGGGACATACATAGGATGCTTAATTTCGCCGTTTGAAATTTACATTCTGAATTATCCAAAAAAAATCGGCAATCTGCGGTTTGTTGCCGGAAATTTTCCATTCTGGCAATTTGCCGATTTGTGCCCGATTTGCCGATTTGATGACCGGAGTTAACTTTCAATTCCTGCAATTTGCCGCCGTTCAATTTGCCGATTTTCCGGAAATTTTAATTCCGGCAATTTGCTGATTGGCCGTTTGCCGGAAAATTCAATTGCAATTTGCCGGTTTGCCGATTTGCCGGAAATTCAATTCCGGCAATGGTGTTGGGTTTGCCGATTTGCCAAAAATTTTGGAATTCCGGCAATTTGCCGGTTTACCGGCCAAATTTTCCAATTCACCGGCAATTTATTGATTTGCCGATTTGCCGGAAATTTCAATTCCGGAAATGTGCCGATTTGACGGAAATCTAAAACATTCTCCGGCCGAATTTTCCAAAAGTATAATTTTTAAGCCCGGCGCACCTGGAATCCCTAGAAGTAACTGCCGATGTCCCCAGTAAATCGTCACGATATTTCTCCATATAGAATGATGGAAAATCTGATAATAGTAATAAAGATAATAATAAAATAAATACAGGCAGGAAACGAAAAGCGAGCACTGACGATTGTATGATACCCGAAACATTCAGGAGGAGCACAAAAAACACAATGAAAAGACACAGCTCAGAAAAATTGAAATTGAAAAACTGGTAACGAGACTAGAATCGTCATGATGATCTTGTAGAAAAAATTGGAAAAAAATTAAGAATCTAGGAAATTGATTAGGTTGCACGCAGACTTGACACGAGCTCGGGCACCGAATCCGCATAGGCCAATGTTTTCGCATGCTCTTGAGCCCATGACGGGCAGAGGGAGTCATGATCGATGCATCTGAAATGGGGATATTATTTTTTACGCTTCAGGTTTAGGCCTATCGACCCCCGTTTGGATCTCCGGCTCAGGTCCTTAAATTGTGTATTCAAGCGTAGGCTCTCTCGCTCCAGCCTTTAGATTTTAACTTCGATCTTAGCCTTACACTAAGCTCTACGACTGATCTAGGATATCATACTAAGGGCCACTTTGGGCCTGAGGCATAGGCTAGTATCTCAAGCTTAGGATCTCACGCTTAAGCTCTCTGACGCAGGCCCATAGATTGCAATGTAAACCTTGGCCTTAGCCCCGACTGATTTAGGATATCAGACTTAGGGCCTAGGAGTTCCGGCCTGAAGCTTAGGCTCTCAGATTCAGGCCCTCAGACTTAGAGTCTAAGGCCGTTAGACTACGATTTTCAAGCTTACAATTAGGCTTTCACTTGAAATCAAAATCCAATTAAGTTCTTTAAAAATAATCAAACATTTCTAAACCGCATACAATTTTTTAAAAACTACCCTAAATATTTCAAATTTTAGAGGTTAGCCTGGACTTAAACCTTTAAACTTTTGGTCTCAAATTTAGCCTACAGGTCTGTGGACCTAAGATTTTGGACCTCGGACTGCGGCCCTTAAATCTCATGCTTGGGCTCTAATGTCCTGGCACGCTAAGTCCTAAATCTTTTGATCGTAGTTTCAGGCTTTCATGCTTTCAGGCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTGAGGCTTTCAGGCTTTCAGGCTTTCAGGGTTTCAGGCTTTCAGGCTGTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCATTCAGGCTTTCTGGCTTTCAAGAGGCTTTCAGGCTTACAGGCTTTCAGTTTCAGGCTTTCAATCTTTCAGGCTTTCAAAGGTTTTCAGGCTTTTATGTTTCAGGCTTTCAGGTTCAGGCTTTCAGGCTTCTTTATAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCTGGCTTTCAGGCTTTCAGGCTTTGAAATACTTTCAGGCTTTCAGGCTTTCGGACTTACCGGCTTTCAGGCTTTCAGGCTTCCAGGCTTTCAGACTCAGCTTTCAGGCTTTCGGGTTGTCAGGCTTTCAGGCTTTCAAGCTTGGCTTTCAGGCTTTCAGGCTTTCAGGCGGGCTTTCAGTCAAACTTTCAGGACTTTCAAACTTTCAGGCTTTCAGGCCTCACTGTTTCAGGTTTCAGGCTGCTTTCAGGATTTGAGACCACAACTAGACCGGCAACACAAGTGTTGTCAAATTACTCACCTCTTTGCCGGCGCTTTATCCGATGCATATTTGATGGTATCTCGATTGTCTTTGAAGCTTTTCAACCCGCCCCAAGTTTCCAGCTGTTGGAATGATCGTTGTAACATCAAAAATCATCATCAAAAATCGTGGTGACCCAAAATTACCTGATTCTCAGCCAAGAATCCATCCAAACTTGCTCTACTCAACTCGGAGACAGGAATGAAGTACTTGACGTGGGCTTTTCCCTTTGCCCAATCTTCTGAGCCACCGGATGCGGGGTCTGGAAATATTTTGAAATTTTCTCACATACATAGGAGCCTTAAGAAATAAGCGCTTACAAAGTGTATCTGCACCGGTTCCAACTTTGTACTGCGTGTTGAAGACACTATAAGCCTGAGCTGACTGAGAGGGCAGTGGATCTCTGAAATATTCAGTAAAATATGACCATGAACTTGGGCAATTCCCGTATTTTTGTAGATGACACCGTAATGGCTAAACACGGGGTGCCAGAGTGTCGCGTTTTGATCTACGTAGATCTGCAAAAAATGCGGGAACTGATTTCTCATCGGTTAAGAACGTGCTGACAAATTATATTGAGCGAAAAATTCCCGCATTTTTTTGTTAAGATCAAACCGTAATGGGACAGCCAGGTACCAACTAAAAAATTTACTCCAACCAAATCATTTTTCAAATCATTGGAATAAGTTCTGTTGATGGCCGAACGGATACATCAAAATTTGACTGAGAGTCCGAGTGGAAGGTGAGGAATGTCGAAATACGGTGTCGCTGCACGAAATCTCACCGCCGCAGTCTCGGGCAATATCCGAGAAGGCTGGTTTAGAGGCTCCCTGATAGATTTCCGAGGAAGGATTGATGAGCCGACTTGTCCGTAGAACCAGTCAAAGTTTCGACTGAGGTCGACACCTTCAAAGACAGCGGGTTGTTGAGGGAGGTTGGGAGAGTCCTGAAAGGTTCTTATTTTTGAGATTTTTAACGTTCACAGTCGGAGAATTGCCGCAAAATCTTAGTTTTCATAGCCTGTGTGACATTATTAGGGCGTATCTAAAGTCCAGAAAGCGTATGCCTTGTGCTGTTTTTGCAAAAATTGTGCCCAGTTTTCCCACTTTTTAGTGGTTTTTGATGGGTTAAACCTAAATTTTCTGAATTCAAGTTTTTACTTTTTCCAACTGTTTTTTCAGCCGTCGAATGGCTGTCCTTTTTTTTGGGCAGACAAAAAAATAATCTTTCTGAATAAGCTAATCGAAAACAATTATAAAAAAGGCAATTTTGTAAATTTTTTCTAGTAAATTTTGAGTCCTCTACAAAATAAACTATTTTGGACGAGTTTCAAAAATGTGAAACATTTCTACAAAAATTGCCCAATTTTTGCCCTTTCTGGTGGTTTTTGATGGGTTAAACCTAGATTTTCTGAATTCTGCGTATATAAATTACACGAACAAATTTAGACATTTTTTTTATTTTTAATTTTTTTCCAGCCATCTAATGATGATTAGTTTTTAACAAAAAAAATTTCTGAAACACAATTATTATAAAACAGGGGTGTGCGGCAAATCTCAAAATTTGCCGAGCACGGCGAATTTGGCAAACGGCAAATTTGGCAATCAGCTAATTTGTTGAGCTTTACAATTCCGCAAAAATTTGATACTTAATTTGAACCACCTAAACTACTAATTTCTGAACAAAACGTGTTCAATAACTTGATTTTGTGCCATTTTTCTAAATTTTTGGAAACCAATAATTTTGACAATAATTTTTGAGGCTAAACTTGTATTGTCAAATTTTTGACGCGGGCGGCAATATTTCAAAAATTTCTGAGCTCGGCAAACAGCAAAATCGGCAAATTTGTCAAATTTGCCCCACATTTTTTTTTGGTTCATAATAAAACACTAACATTTTAGATTTTTCATAATTTCCCGTCGAAGGTTTAGCAATTGCTAAAATTCTGAAAAATCTGAGTATTTTAGGAAACCCAAAGCAATGCGGCATGTTCCGACCCCAATGTATTAATACAAATGATTAAAACAAACGAAATTACAGTAGACAAAATGTAGAAAAAAAATTATTTTTGGTCGACTCCAAACGAATTATGAGTGGCAAAAACTTTGTAATAGTCACCTTTTGACAGTAAATAAATTAGAATTTTTTTGAAAAGTTTTATTATGATATTCGGTCATTGTGGGACCAAATGAGTGGTTTTTAACTATTCCGGCACTGGCGCAGTCCAGCATTTGCCGTAATCTTAGTTTACATAGCCGACATATGCGGGCCTAACTGAAGCCCAGGAAGCTTGTTTACAAAAATGAGCAAGCAGAAAAAGATCAATCTCCCCAACAAACCTCTTGCCTGTTTATTACACTTTGGTGGTGAGCGATTCTTTCTCCATAGTCTGATCTCCGGATGTACATAGCTACTTCTACTGTACTCATAAGCATCCGGATTCAGCAGTGGAACAATATTCCATTCGAGTTGATCTACGAATTGCATGATTTGAACATTTGTCGTACTGGGTGACCAGTTGGTGAATGAAATAGAGTACTGTCGATTGTGACACCCATTCACGAGCATGGATTCCTCCGTCCACCCAGATGCCACGTTTCGTACGTTACGCTTGTTGGTGATCTGGAAGTGAGGAAAATTGGGGTGAGATGGGATCACTAAATTGTTAATAGTTTCTGTGCTTCTGTGTTTATGTTTTTTGCGCTCCATTGGCAAGAAATCGCCTGCCCATCAAAAACCGTCAAAAAGTGGCAAAGCGGGGCAACTTTAAATTCCCAATTTTGAAACTCCTCTAAAATGGTTTAGTTCGTAGATAGAGAGGACTTAAAACTGATTTTTCTATAAATTGTCTAAATTTGTATTGAAAACGGGTAATTCTTGTATATCAGAAAATGGTTTAACCCATCAAAAACCATCAAAAAGTGGCAATAGTGTTCTCGGCCATTTTTGCGTGATAAAAATTCACAATTTTGAAACTCCTCTAAAATGGGCTATTTTGTAACTACTCAACATTTCCAAACTCTAAAGAATTGTTCAGAATATAGTGGTTTCAATAATTTTCGAACAGAATGTTTTTTGCCCAAAAAAGGATGGCTGAACAAAAGGCCGAAAGAAAAAGAGTTTTACACTGAAAGCAAAATCGTGACGCGACACGAAAGCTAGGTAAATCGACCCCAGCCGTTCCAGGCCGAGTTCAAATTGCCAAATTCGGCAAACTCTCACATTTCAGGCTATGTATTTCAAGCGAGAAGCGCGTGCGATTTCTCAAAAACCGGCAACTCAGTTGGGAGGACTTTACGAAAAAAAATTCCAAGGTATAATTGGTAGGTTTAGTCATGTTGCATGGTACTTAAAATGTTTTTTTAACTTGCAAAAGTGGCTTTTATTTTGCTTCTTAGTTTTGCAAGCCGAATAATAAAAATATTATCCACGTTTTTAATGCTTCCATGGTAGGCAGCCGCTCGCCAACATGGAAGCCCTACATGTCACGGATTTTTCGCCAGAAATTGAAATGTGGAATGAGCTATGCCGTACGAGGCCAGGCCATATCTGTGGTAGATTTACGGCGCGTTGCATGTCGCGTCGAGGCTCGATTTTAGTTGAACAACTAAATGCATTGTCCGAGTGGAGTACACGACTTTCTCACGCGGGCGATTGCCAATGGCGCGCGAAAAATTGAATAAGAGGAGGGCCAGAATCCCGTGATCCCGTCCAAGCAAAGTTAAAACAACAAGCAAACCTTAATCAACGGGATCTGCCGTCCTTCGTGAGTCGAAGTTCCGATTGGCTGCAGACACATCCGGATATGGTTAATGACGTTCAGGTAGTTGATAACATCATCAAACGATTGGTGATAGGCGTTGTGCAAGGTTAAATTGAACCTGCAATTATTGAACTATTATCATTGAGGAGAACGTGGTGTCTGGGTGCCTCATTTTAGATTGATCGCTGATCGACAAAATGCGGGTGAAGAGAATGATTTCGAATGGTTAAAAACGTGCTGACGTCACATCTTATGGGCTGAAAATTCCAACGCATTTTTTGTAGCTCAAACCCTAATGTGACAGCCTGACACCACATGTATTCACTCACTTTCTGCGGCTCCCTCCAATCATGCAGTCGAACTTGATTCCGAAGCTAATCCCGCTTCCTTCTGCTCGACAATCACTGTGAAATGATCGATGAAAAGATAAGTTGGGCTTAATAGTGTCCCCCCACGAATACACTCATCACGCGTAACGAGCCGTGATGCGCGGTGGTTTGAATAAAGAGTATTTGGACTAGTGATCCCCCGCGAAAACCTGTATCGCGACTACGTGATGCCAGGGTGTCTCATCACGCGGGTTGATCTACAAAAAAAGCGGGAATTTTTTGCCCAAAAATGTGACGTCAGCACGTTCTTAACCCTGGAGCACCGAATTGAAGCAGTTCCCGCATTTTTTGTAGATCTACGTAGATAAGCCGAGATGACACACTCTAACACCACGTGGTATGCGCCGAAAAACTCACTTCTGAACGGCACCAATCATCGTTAACGGAATGCTTAATCGAAGGATCATCGAGCTCTTTCATAAACTGCCGTGTTTTCTCATCGGATATCATCACATGAAACTCCTTGCAAGCTAAGCTCCGACGGGGATTTCCAAAAATCTAGCGGAAAATTTTAGTGTGTCCGGAGGCACCCTAGTATACTTATATTTCAAAATTTTTCTCTAACCCCTCAAAACCGTACTCTACATCGCCGTACTGGCCGAGTGGTCTAACGTTCAGGTCGCAGTCTCCGGAGGGCGCAGGTTCGAATCCTGCGGACGGCAGATTTCTTTTTAAATACTACTCTTCAATGCATGATGAAGAAGAAGAAGAAAAAGAAAGAACGTATTGGCTTTTACTTTTACACTTTTGATAATCCCTAGGAACAGGTTATAAACAGCGATGCAACATGAAAAGCAGCAGTGAGTGAGATGGACAACGAGCTGATTTTGTTCTTCAATTATATGACACCGCTATTTTAATGGTTGGTTTGTTGCGTGGAACATCATACCTTTAAATGGTTGAATTACAAATCATGTAATAATAATGTCTACTTGATTATCTTGGGTCGTCGGCTGCACCATCCATACTGTGAATTTTCTGAAGAATCTTTCTGAGAGTTTACCGGCTGTTGGGGGAGAGTTTACGATTAACGTTTGAGTTTTTGGATAGATCTAAATCTAGAGAAGATCATGCGGCGGTTAGGTATATTTGAAATAAAAAACAATTGACCTAGATATGAAACATGGAGATCTAATGGATTTGGTAAAGTTGAAATTATTATTTTTTTGAAAATTTGTTCATTTTACAAGAAAAGACGAATAAATATTGACCAAAAAAATTTTTTTCAATCAAAAATGTATAAAAATTAATCATCGTTCCTTTTAGCTTTTAAACAGCGGTGGAGTAGCCAGTGTGGATTTTGTCTCCCTAAATACAGTCAATTATTATGAACCAAAATTCAAATATCGTGTAATACAACACTTCAAAAAACTTCTTTATTTCAGATTTTTCATAATTTCTGGCCAGACTTTTTGCAAATTTCCAAAATTTTTCAGAATGTCGAAGTTTCCGACCCCTGCAATGTTTTAATAGAAATGATTGAAACAAAATTACAGAATAAAAAATGTAGAAGATAACTTTTTTTTTTTGGTCGACTTCCAAAATTATGAGTGGCAAGAACTGTGCAATTGACACTTTTGTGAAAATAAAAAATTTTAAGAATGTTTTTGAAAAGTTGTATTATGATATCTGCCTCGGTCAGTTTGGGACCAAATATGAGTGGTTTTTAATAATATTCAGAAGCCACTGGCGCTACTCCCCGTTTAAAGTTCTATGGTTTTTAAAACTCACGTTTTTTTTTATGAAGTCTATTTTAAATCTGGACTCTCAGTCGACAGAGGTTCAGCATTTTTCGAAATTTCAGAAATTTAAAACATAAGTCGGGTCCTAAAAGCTACAAAAAAATTCTCACAAAATGTTTTTTTGATGAAAGCAAACTTATATAGGAGTGCCAAAATGACCAAATTTTGGTTTTAAAAATGATATTGAAAAATCTTTAGAAAGTCTCTTCTGGTTTTTATTTATTTTTAAAAAATTCATATTGAAATATTATAGTGCTTTAGATTGCTCGGAAAAAATTCCACACATTTTTTAATTTTTCATTAGTTTTATAATGATATTTGGTCATTTTAGCTATCTCGGGTAATACTGCAAAGCCACGTGGTGCCAGGATTTCCCATTAAGGATTGATCTACAAAAATGCGGGACTTTTATTCCGCTTAAAAAGACGACGTCAGCTCATTTTTAACCATGCGAAATCAGTTGAAAACTGTGCCGCAATGATTTTTTGTAGATCTAAGTGGGGAGATCAAACCGAAATGGTGAGACATACTGGCATCGTGTCCACCTTCATAGTTAGTAATTGCATAAACAAAAAATACTGAGAATGCGTATTGCACAACGTATTTGACCGAACGCGCAAGAATATCTTGCGTTGCGAAAACTACAGTAATTCATTTACTACTGTAGGTTGGTTTGCCACGCAGGCTGGATTTTTTGAAAAATAAATGAATTAAAATAGTTAATGGAATATTACTATCTCTATGTATTAGTAAATAAGGTTGAACCCGTAATGAGACCGCTGCCTACCTGCCTGATTATAGATGGCCGCCCTAAAATTAGGCAGGTAGGTTTTAACGCCTAGCCAGATACAAAACTTAAAGAGAAATGCCTAAAATAACAATAACTTACATCCTTTCTTATCGTCCTCCCCGGCGATCGCCTAAGATCATAGCTAACAACTAGCCGCTTTCGGTCATGCAATTATTATATTATAATTGATGGATGGATGGGGGATAATCCAGAGAAAGGGGTGAAAAAAGAAACATACCTAGAAAACAGGTTCCCCTGACTCAAAACCTACTTTTGATGTGCCACCACGGATGGCACGACGAGATACGATGATCACGTGTTCATCTTCATCATTTTCATCGTAGTAAAACTTGGGGGGGCTGATGTGGGAAGGATGCCCTCGTCAAGTGTTCGTTGAACAATCCGACACGGTTATCAAAAAAGCAGTGGTGTCTCCGCCCAACTTCCGCGCGTCAGCCGCCCTGTGTACTGTCTTGTCCTATAGCTCTCTTTTCTCCACCCCGGCTTGCGGGTGAGATTGTTCTCATTACTAGGTGAAGAACGTCTCTAGTAGAAGAAGAAGAAGAAGAAGACGACGATGGAGAAGAAGCTGAAGGCACGACGCACTGTTTGCGCCACGATGTTTGTTGTGTTTGCGAGCGTGAGCGCCGCAATTAAAACGTGTAGATCGGTTTGAAAAGCGCGCGCGCGCGGTCATCTTTCTCCGCTTGCGCGCACGCATTGACAAAAGACCGAGACAAAAGGTTCAAAATTGAAGAGGCAAACGTTCGTCCTCTTAGCACCTAAATGTGGAAGCATAAGATTTTGCTCTGAAAATGAAGTTGGGTAAGCTATTCCTGGGTGATGTTCTCAAATTCCGGGGGCATTGTTGGGAAAGTGAGGACCAAAATAGGCCATAAAAAATGCAGATATACATGCTAAGGCTTTGGGGGCTTAGGCGCAGATTCAGGCTTAGGCTTAGGCTTAGGCTTAGGCTTGGAATTAGGCTTGGCGTCAGTGGCGAGCGTGAGCTCGCCACGGACGCTATTTAATTGGGTTTATAACGTTTTTTTTTCGAGTTCCCGTCGAGCGAAATTCAACTGAGAGTCGTATAGGCCGCCGAGAACCTGACGTTCCAAATAGGTGACTTCATTAAAACTCTTAGGCTTAGGCTTAGGCTGTCACTAGGCTTAGGCTTTTAGCCATGCTAGCTGATCCCGAACATATTTTTAAAAATTGCAATATGTGACCAAAAGCTGTATTTTTCAAAAATCCAAAAGTACGCGAAATCATATGAAGTGCTTCTTTTTCTTTCAATAAACTGTTCAGAATTGTCATTTTTACTAGAAAATACCACAAAAATATGCTAGCTTGACCGGAACATATTTGAAAAAATTAGAATTTTTGACCAAAAGCTGTTTTTTCAACAAGTTGAAAAGAACTGGAAAATCATATGCTTCTTTTTTCTTACGTAAAACTGTTCAGAATTGTCATTTATACCAGAATATATTAAACAAAGTATGCTACCTAATCCGAAACATTTGTTTCCAAAATATTTTAAAAAAAAGATTTAGCGGCTCTGACTAAATTGTTTGTTCGTTTTTTCTGGTTTTTCCACTTTTTCGGTGAAAAATTTTGTAAAAAATTTGACCGAGGTGCGTGTTAGAGTTGAATTCATCAAGTTTTGACATTATTTTAGTACGGGCACAGTTGCTGCAAACGAAATTTCCAATAACGCTTATTTCTCGGGATAAAGTTATTCTATTTTTCTTTGCAAATCTGCTAATTCTACAAATCTACTAACCGAGGTGGAGTTGAACACCTTTCCAAAAAGAAGTAGCAGTCCTGAAAATGTTTTAGTGAGGCTTCTCATTATTCTAGAGCCCGAGCCACTAATGTAATTGTTCCAGAAGTAGTTTATAAATTTTTGAACTGATTTTATCCTCTCCATGATAGAGGAATTGTTAAAATTTTCAGATCAAATTGGAATTTTCACAGCCAAATATTTTGGTAAATTTTCCACAAAAAATTGGGCGGAAATTGGAATATTAATTTGATTTAATTCGATTGGAGCAGAGTGTATAATTATTCAAAGTTTCCTCCCTTAACAGCCATTCAAACGCATTCGGCTTTTTTCTTAGTTTAGTTTTTCTTATATATGGCCTGCAGGCTCTCACCAAGTTCCGTTTTACCGGAGAGTTTAAGTGCACAACAAATCCTGAGATCCCATGTTGTAGTTTGTGAAGACGATGAGGTGTTTGAGTAGAAAAATGAGAAATGTTCTAGTATTTAAATATTATAAATTGTTTCAGCGAGAACGTTATCAGTAAACACCATTACGTGTTCCATACATATGCACCACATATGTCGCTATCTCGTTAAGGCTGAAGATACCAATGACGGATTGCCAAAGTTTTTGGATGTATTACTTTTTTTCCGTTTTCTCTAGTATTTCTCAGAAAATTTGAATTTCCCGGTCACCAAAATTTTCCGAAAATTTGAATTTCCCACCAAAATTTTTTATCAGAAGATTTGAATTTCCCACCAAAAGTTTTTCAGAATTCAAAAAATATGAATTTCCCACCAAATTTTCATTTTTTCTCAGAAAACTTGACCGCCAAAGACTTTTATCTGTCTCAGAATTTTGAATTTCCCGCTAAAAAATGTTTCTTAGATTAAAAGTCCCGCTAAGTAAAAAATTTTCGTGAAGAAAACTAAAAACCCCCGCCAAAACTTTTTCTCACGTAGGAGTTTGCATTTGCCGCCAAGAAGTTGTTTTCCATAAAATCTGATATGAAATTCCCACCCAAATTTTTTCTCAGAAAATTTGAAATTCCCGCTAAAAAATTTTTCTTCAGAAAATTTGAATTAGTCCCGCCAAAAAATTTTTTTCTCATAAAAATTTCGCTAAGCCACCAAATTTCGCAGAAAAAATACCCGCCACAAAAAGTGAACATTCTAGGAGTTTAGACTGACAGTTTACCGAAAAACCTTGACTGACGATTTTGGAAGATCGAATAACCTCTTAAATAAAACCTCTAACTCGTAAAAATTGAAAATTTAAATATATAGCTTTGCAGTCCTATTTAGACGTGTTATACATGATATCGTCCACGATTGCACGGAGAATGGGAAATATAAGTTGTTGAGTTGACTTGGGATCTTATTATATCAAGGATGGGTTAGGTACTTTAGGGCAGGCTAGCAAATGGCTTCCACGTGAAGCAGAAGCGGTTTGCCGGCTTCTCGCCTGATTCCTGCACTTTGGCAAAAATTCCAAGCCTCGATGCTCACACATAGGGCTGGCTTGGACGTCGCGTCGGTTTTTGGCAAATTTTAAATCTTTCCGAGATAGTTTTTTTTGTACGGCGACGTCCGACAATTTCCGAGTTTGGCCACTCATGATTATATTGGATTAAGTATAGTGCCCCGAGTGGCCAAACTCGGAAGTTGTCGGCCGCCGTAAAATAAACTACCTCTCGGAAAATTTTAACATTTCAAAAAACCGGACGACCGGACGCCATATGTCAGCCCTACTCACACCAAATAGTACGGTCTATAAGCGGTTTTTTTGCCGCAGGCCGACACTTTATGGTTTCCACGCCGCACTGTACAGAAGGCGCGGCCCGAGGCAGTTGTCAGGCGTTTTAGCGCCTGTGTGCAAGCTCTAGGGCAGGCATGTTTTCAAAAAAATGAACATTTTCAGGCAGTACGATGAAACCCGCAACCTTGATCTGAACACTGCCGGTGGGACGAATGGACATACGAAGTATCGGAAGAAAGGCGATAGTGATGTCCAACATATTTATTTGCAATGTTTGATAATAATGTTCATCAATATTCGAGCCTACGTAGGCTTACCTGCCTACAAAGTAGCCTACATATATTATTTTTGCTAATTAACAAAAATAATTAAAACATTATTAAGATTTGCTGAAAAAGCAAAAAGTGTTTTTAAGTTCGACTTTTTGCCCAACAGGTTTACGTTAGGCATGTGACAAAGCCTACATTCAAGGTAATCTACGCCTGCCTCGGTACATGGTGCATCGACCAATACTTACCTCTTAGCTTCGAGAGGTTATAACACGGTTACATTTCGCTCTATCAAAATAAGTGGCCAACTGCAAAAACTGTTCTCCAATGCTTTTTCTACAATTTTGTGGTTAAAATTTTTTTAATATCTACACTAGCAAATATAAGCCACCAACCCGTACAATCCGCGCCGCCCCCCGAGAAAGCAATTCAAACCCAAGTTTATTGCAATAAAAACAACACAGTAGAAACGAAAGAAATGAGGTTGATTTTGGAGACTTTTCAGTTGGCACGGGTTTTACATTGTTGGCATTATTCAGATTCGATTGAGAAGGAGAAGTCGTGGGGAGGCTGAAAAGTTCTAAAGTTGTTGAAAAAAGTAACAAATCTGCACTTTTTTAAAAACCTGATTCTTCAAGACTTCCATCCATGGCCATAAGTGCACTGAACAGTCTGTTGCTCTTGCTCTTTGTGCTCCGTGTCCTCGGAGCAATCATCAACCTTGTCTGGAACTGTCGGTGTTGGTCAGTTGACGAAGCCAAGGAGGAGGATGGTGTCGCAGTCTTTGGTTTGGGAGATGAGGGCGGAGCTGGCTGAATAGCGGTGGAATTGGAGATGCAATCTTTTTGGGGTTACTGCAGACTGTTTGCTCAAACTCTTGCTCCGCGATTTTGTGCTCTTTTTTGGTTTCTTCTTTGAGGGCTGGTTGTGTTGCTTCTTGCTTTTATCTGAAAATTAGAGTTTCTAGGCAATCAAGCGATTTTCTAGGCGACCAGACATATATTTAGCCATGTCGGAATTTTCTAGGCCAACACAAATAGTTCTAGGCCATATAATTTTCCTAGGCCACGTAAAACTTTTCTAGGAGACCACCAACAGTTTTCTATGACCGCAATTTTTGCTAGGCCACCAACAAAAGCAAATGAACATAAGACATAGGCCACCAACAGAATTTCAAATTTTTCTAGGCCTTTAACTCACATATTTCACAATGGAAGCGGCGGCGAACACGATGAAGGGTACAATGAGAATGCCAATGATTATGCATTATCACTACTTTGGTCCTGGCGTAGTCGATGTCGCATGCTGCAAAAATGGAGGTACAGGAAATCAACATGCAAACGCGCTACCGTGGCACTAGCAGTGCGGTAGAGCGCGTTTCAAACTAACAGCCAGAAGTTGGCGCCGGTGCTCGCTGAGTGGAGGTGGCCATTTTATCGGAAATGAATGAGAAAATGGAGAAATTTGGGAAAGTTGATTAGAGACGTGGGAGTTTTTTGAATTTTTATAATATTTATGAGTAGGGGGAAGGGGTGAGGGTCACAGCAGGAAAAGACCAAAAATTTGTGATTTTTCCATTAAATTGGAGGAAAATTGACACCATACCTCGTGGCCTAGAAACTGCAGAATTTCTAGGCCACACACGTTTCGTCATAATTTACCTGTTAAACCAGGTAAACTATCAAATAAAGAGTGATTAATCATCTCCTATCTTCTTTTATTGCTCAGTTCCTACTCCAAATGTTTTCTTTTTTGTAATTTGTGATCACAAATTGTTGCATTTTAGTACGCCATGTACGTCTGTGTACTACTTTTTTCTGAAAGAAAAAATGTTCGCTTTCAAGAAAAAATAGTGAGAGGTACAACCGAAAAATACGGGGGACTAGAAATATGTGAATAAGAGTTCGACAACCTAGGCCGGTAGGCAGGCAGGCGAGTAGGCAGTTAGGCAGGTAAGCAGGTAGGTAGGCAGGATAGTAGGCAGGCATAATAACGTTCAGATGCAGGCACGTAGGCGGATGTTTCGAGCAGGCATGAAAAGTCCCGGGGGTAGGATGTGGGTATGTAAGCAGATGTCGGTATGTTGACAGTCATGCTGAAGGCACGTGGGTAGGTAGGCAACTAGGCTGAGGGAGTAGACGGTCGGGTAGGCAGGCGTGAGGCAGACGCGTAGTAAGAGTAAGCCAGGTTGCAGGCACGTAGGCAGATGTAGGATGCGTATGTTTCTTGTAGGCATGCTGAAGTCATGTGGGTCGGCAGATTGGTAGATGTAGTACGCAGAGTAGGTATGTTGCGGGTATTATGAAGGCACGTGAGTGGGTAAGAGCAGAAACCGCAGGTAAGGCAGGCAGGTAGGTAGACATGTAAATATGACAGGCATATACGGAGGGAGAACAAGCCATAATTCAGGGTGGCACTTAGGCAGATTTAGGTATGTTGTAGGCATGATGACGTAACGTGGGTAGCAGAGAGGCACGTAGGCAGGCTCGTTAGCTGGCAGGCATAATAAAGACACATAAGCAGGCATGTAAATCTGCGGCAGATACGTAGGATCACAAGAGCAAGATGTAACTGGTAGGCACGTAGGCAGGTGTAGGTATGTTACAGCCATGACGGTGGGTATGCAGGTAGGTAGGCAGCCAGGCAGGATAGGTGGGTGCATAAAAGACAGGTAGGCTCTCGGGTAGACAAGCATGTAAAGGTGCAGGCAGATACGTAGTAAGAGCAAGCTAGGATGCAGGCCCGTAGGCAGATGTAGGCATGTTGCAGGCATGATGAAGGCACGTGAGTTGGTATGTAATCGGTGAGTAGGCAGGCATGCAGGCACATAGGCAGATGTAGGTATGATTAGGCAGGCAGGTAGGAAGACTCAATGCAGCCGTGGTGCTAGAGCGCCCCTTCCTAGTTAAGACAATCTCGTTATTCTAATAATAAGCTATTCAATCATGTCACCGCGCCGCATACACAAACTACCTGTTTTTTTGAGTATGAGTCTCGCCCGTTCTCTGACCAAAAGCTTCTACAGAGTGATTACACAGTATAAGGGGTAGAGAGGTTAGATTCAATCATGTCTCACTTTTTTCCCTTTCTCTGATTCTTCCTTCTCCCTTTTTTTACAGGGCGCTTTTCCCTTTTTCGTGCGTGAATATGAAGAGAGAGAGTGCATACAGGTGTAGAGGACGCCCAGACATCGAGACGGAAACAGGTTCTTCATCGTCTTCAGTTATTTGGAAGCAGGAGTAAAAGGTGACGGTGTGTGTTTGGAGACGTGTAACCATCATGTTTTATAACACTTCCTTGCTCATTTTTCTCTGCTTCTCTGCCGTCTCTCTATACACACAGTCTTTCGCCGTTTATTTATTACCCAATCACAGACGGATCAGCTATACAGAGGTTATACAAAAAGCGACGGCGGATACCCTCATGATGTGAGTTTTGTTTTCGCTTTTGCAGCAGATACAATTTCTAGGCCACCAAAAATTTTTCTAGGCCGTTGAAAAAATCACTATTTCTAGGGACGTTCACAATTTTGAGCAAGTTCTAGGTTGATGAATTAGATTATTACGCCATGGTGCATATTTCTAGGCCATCAGGAAATTTTGCAGGCCACCGTTTCTGATGCAGTTGAACTAAGTTAGTGGCCTAGAAAACCCTTTGCCCGTTAGCCTAGAAATAATTACGGCGCCCTAAACACATTTTTGGAGGCCTAGAAACACTAACTTTTGGTAGCCTAAAAATTTTCTGTGACCCACATGGAAACATTGTTGGCGGCCTGAAAACATTTTTGGAGGCTTAGAAATATTCTTGGCAGAAAACATTTTTGGTGGCCGAGAAATTTCTGGCCTAGAATGTTTTTGTGGTCTATATTTTGGCCGGCATAAAAAAATTTGGAATGGCTTAGAAAAATTTTTTTGGTGGTTTACAGCCACTTTTCAACGACCCGTAAAGAAACATTTTTGGTGGCCTGAAAAGATTTTTGGTGGCCTAGAAACATTCTTGGTGGCCTGAAATTCACATTTTCGGTGGCCTAGAACCATTTTTGGAGACCTGGAAATGTTTTGGTGGCCTAGAATATTTGTCGTGGCCAAATAGAATATTTGTTTGTTTGTCTAGAAATATTTCTGCGTAGAATGTTTTTTGGTCTATAAATAATTTTGGTGGCCTAGAAATATGTCTTGGAGACCTGATATCATTTTTGGTGACCTCGCATAAATATTTTTGACAGCCTAAAAATTTTCGGTGGTCCAAGAAATATTTCTGATGGCCTATAATGGTGTCGTGGTCTATAAATATTTTTAATAACCTAGAAACATTTTGACTGGGGGCCTTGAAACATTCTTGGTGGCGCCCTAGAAATGTTTGTTTCCTAGAAACATTCTTCGAGAAACCTGAAACATTTTTGAATCTGTGGCCTAGAGACATTTTTTATGGCCTAGACACATTTGGATTTGGTGGCCTAGAAATGTTGCTGATGGCCTATAATGTTTCTGTGGTGTATAAGTATTTTCGGCGGCCTACAATATTTTTGATCGGTGACCTAAAACATTTTTGGAGAGCTGGAAATGTTATTTTGATTGCCTCGAAACGGCTTATTTGTACTGTGCTGAAACATTATCGGTGGCCCAGAATGAGACCTGAAAACATTTTTGGTGGCCGAAAAAATTTTAGTGACCTAAAAACTTTGGGAATTACCTGGAACCAATTTTGGCGACCTAGAAAAATTTTCCGGGGCCTACTAAAAATTCCCAATAATTAACAAATTTAGCTAAACTACTTCTGGAAAACGGGGACAAGCACGGGTCTTGGCATGTGATGGGGATATGAAGAATTCGAAATATTTTTTGGACTTTCTACAAGTAAGATATTTCTTACATAAAGACGAATCGTGGAGGGGTGAGCTTTTTCTGAAATTTTGAAAATTACATGATGATTGGAATATCTATTGATAAACGGTTAGGATCGCAATTTAACGATGATCGACAAGAATCTCCGTAAATACACAACGGCACCACATCTCAAAAATTCGTAGGCCACACGTGTGACGCCATTTTTCTTCCAGAATAACAAAGCCCGTGAGAACAACAAGACCCTCTCGAACATGTGTGGTCCCCCGTCTGTGGGATGACTCCTCGTCTGTCATCTCATTATGACTTCCACACCTATGGATCCTATCAGCGAATTACTGATTGGAATCAGCTGGTGGTGAAGTACAAAGATGGTTCAGTATATATCGATTGGAAAAATACGGAGGGCAGGAATATCGGTGGAGTTGAGGTAGGTCTAGCAGGCTTCGGTCTAGGTCGAAGTCTAGGTTTAGGTCTAGGTCTCAGTCTAGGTCACTTAGGTCGAGGAATCTAGGTCTAGGTCTAGGTACTAGGTACACTAGGTCGAGGTCTAGGTCTAGGTCTAGGTCTACGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTTTAGCTCTAGGTCTAGGTCTAGGTCTAGGTCTATCTAGGTCTAGGTCTAGGTCATGTCTAGGTCTAGGTCTAGGTCTACTAGGCCTTCTAGGTCTAGATCTTTATAGGTCTCGGTCTAGGTAGGTCCTAGGTCTAGGTTGTCTAGGTCTAGGTCTAGGAGGTGTACGCAGGTGTAGGCCGATCGATTTCTATGTGTATTAGGCCTCATAGTGATTTTCTGAGATCGGCGGAGACTCCCGCACCAAAAAGATTTTCTGGATCGATTGAAGTATTCATGCTCGAGAAGGGGCGGCCCCGAACACGCCGGTCCCTTTGTTATTCATCCATCAGGTATGTGATCCGGCCCCGTCAGAAAAAGTGTGTTCCGTTTAGCTCCGCTTGACACAAATGTTGGCAGAGACAGAAAAAGGGACACCTTGATAACAAATGGGTTGGAAAACAAGGTAATCGGATGATGCAATCGCGCCCTATTGCACTACCTCAACAAAACACTTTTCCCAGTTGCAGCTTACCTCCAGGGAAAACGCGCCCGGAATCAAGAAATTGCTGAACGACGTAAGATCACATTTGTAGTGGTTCCCTGATTGAATCCAGTATGAGTTCACGAGGTGCTCCACCCACATGTAGGTTGGGGTAAGGTTACTGTACCCCCCCCCCCCCCCCTCCGCAACTCAGGCGCAAGCACTCCCAGCGATTGCAGGTACCGTTCGTCTGTGGTTCCGTAAGCTCGAAAAAGCAATGCCGTAAGGACATTTGGGAACGCAATCACTGCTGTCGCGGTGACGATTTGAATCGTAATTTCGATTTACACTTTAGAGATGAGAGAGAGGGTGAAGTGGTTTTTCTGAAAGTGGACTTGAAAATTAAGAGTCAAAGTTTTGAAAGAAAACTTTGACTAAAAAAAAACACCCTTGAGAATTTGTTCGAATATACGTAGTTGCTGAAAATTAACGTTGTGGAACATTCTAAAACCATTTGAATTTAAATAATTTTTTAAACATACCAAAAAATCATGGGTTCCAAAATTCACGAAAGTTTCGAAAGGTGATTCCCTACTCCTGAACAAACCTCCCCTACAGTATCCTTAAAGTACCCTACTCCAGTACCTATACAGAACTCCTGTAGTACCCTTACAGTCCTAAAGTATCCCTACAGTACCCCTACAGTTGCCCTATAGTACCCCTACAGTAATCTCGCAGTATCCTTACAGTAGCCCTACAGTATCACAGTACCCCTACAGTATTCCTACAGTACCCCTATGAACAGTAGCCCTACAGTAGCCCAATCGCACTGAGCCTTACAGCATCCCTAAATTATCCCTAGATAATCCCTACAGGTGTACCCCAACAGTACCCCTACAGTACCCCTACACCATCTCCATAGTACCCCTATAGTAGCCCCAGTAGCCCTACAGTTCCCAAACAGCCCTTATAGTGCCTATACAGAACCCTATAACATACAATACACCTACAGTACCAGTACGTAAATTACCCCTATAGTACCCCTACAGTACCCTGGCGGTACGTACTCCAACAGCAATACCCTACAGGACCCCCATCCCTACAGTACCCCTGAAGTACCCATACGGTTTCCTTACTGTATCCCGTGAGTATCCCATTACAATACTCTCACAGTACTCAGTACCCCAAAAGTTCCCATACAAAACCCCTACAGTACCCCGACAGAACACTCACGCTACACTCCCGTATCCCTACAGTCCCTGAAGCTACAAAAATTTCCCCCCAACAATTCAAAAAAGCGGTACAAGACGAGCCCGTGCTCAGAGATCTACCAGGGATCCTCTCGATTCAGTGAGCCCGAGGCAAAAGCCGTACGGGACGCGTTGTTGTCGCAGAGATATTAGGGAAGAACCGACGCGCGCCTATATCACACTACACACTTATTCACAGGGAAATGCAGTTAAGCAGTCGTCTTTTTCTCGGCCACCGATCACATTTTCTCGGCCATCGATATTTTCGCCATCGAATTATTTTCTCGGCCACCGAAATTTTTCGCGGTCATCGATATACTCTCGTTCACGCGATATTTTTCCCAGCAACAGATTTTTTTCTCGGTCACCGATATTCTGCCACCAAAATATTGTTTTTCGTGGCCATCTATCCCATTTTCATCGGCCATCTATATTTTCTAGGACACCAATTGTTTTTCTCGGCCTCCCCGATACTCGGCTACCAACATCGTTTTTCTCGGCCACCAATTTTTTTCGGCCTACATTTTATGTCTCGGCCATTAATTTTTGACGGCAATCCGAAATTATTTCGGTCACCGATATTTTTCACGGCCATCCGCCAGAATTTTTTGAAAATTTGATTTGAGCAAAAATCTTCAGATTTGGATCACACGTCCATATGGTCACAAGAAGGATGCATATCCAGGAGATATTAAGGATTTGGTGAGTTGGATGACGCGTCATTCTTCTTGAAACGTTGAAAGTCAGATTTCCAGTACGAAGTTGGCATAAAAGCTGCTCAGGCTCTGAAACGGGTTTACGGCACAAAATACGTAGTCGGAAGCGGTGACACGCACAACCCGGCGTCTGGAGATCTGAAGCTTGGGCAAATATAGGCGCGAGGCGAAGGTCAAAGTTGTGTACCTTCTAGAATTGAGGCCCGACGAGAATATAAAAAAAACGTTCAAAGTTCCTGAAAAGTTGGGCGATAATTTCAGCCTGGGATGGGGTCATAACGAGAAGGAGCTGATCCCGACACTCGGGTCTGGTTGAAGGTGTCCGAGTTGTGGCGGAAGCTGTGCTCGATCGGATAGTAGCCGGCAAGTCGACGGATGCTCCAAGAGGTAGGCAAACTTTGATGTGCCTGCGTTCCTGCCTTGTGCCTATAGTTTACGAATAGGCACGGAGCAAGTAGGCAGCAAGCGAAATGTGGACCGATAGGCGTAAGGTTAAGGGCTTGCGATGCTTTTGCGTAGCGAAAAAAAGAAAAATTTTTAAATTACAGTGCTCACGGCCTAAAGGAGATGGCTTCTTAGGTAGTCACTACGATGCTCCTTGACTCTCTGACCACAGCCCCTTGGTTTCTCGATTTTTCGTTTTAGAAATTACACTTGTTTATTTTATGATTGTTGACACGCTAAATGTTTATTTAAACATAATTTTTCTTGAAAAAACAATTTACATTTAGAGAAAATAGCAGCGAGTCGTGGCCGCGGAATGAAAAACTCGACCACCAGCTATAAAATTAAAACGTATAATAATTTGGTGGTTACTCAGTTTTGCAGAAAAGAATGGCTGGCCGAGTTTTCACGTTTCTAGGCCATCGGTTAGCAAAGTTGCTCTGAAGCGCTTTCGCGAATTCGTTTCCAAATAAAAACTGTAGGTGAAAACTCGACCGCCCACGCATTCTTAAAGCCACGAAATCGATTGGAAGTTCATAATTTCTCGGTCACCAATTTTTTCACGGCCACCGATATTTTCTCGGCCACCGAAGTATTTTCTCGGCCAATCAAAAGTTTTCTAGGCCACCAACTTTTTCTCGGCCATCTATATTTTCCCGGCCTCCGACATTTTTTCTCGGCCACCGATATTTTTCGCACCCGTCTATATTTTCTTGGCTACCAATTTTTTCTAGGTCTCCGATACTTACTCGGCTACCAACTTTTTGTCATAGATATTTTTCGCAGTCATCTACCTATTTTCTCGGTCAGCGATTCTTGATAACCCGTGTTTTTCTCGGCCAACGATATTTTTCTCGTGACCATCGATATTTTCTACCGGCCATGCCAAAATTCATTCTCGGAGCCACTTATATTTTTCTCGGACACTAAATTGATAATTTTCTCGGCCACCTATATGTTCTCGACGACAGATTTATTTCTCGGCCATTACTCTACGGCCTCCACCGACCTTTTTTTCGGTCACCGATTTTTTCTCCGCCATCTAGATAATCTCAGTCACCAACTTTTTTCGGTCATTGATATTTTCTCGGTCACCAATATTCGTTTCTCAGGCATCAATATTTTTATCGTCCACCGGTATTTTATCGGCCACCGAAATTTTTCGCGGTCATCGATACGTCACGGATATTTTTCCCAGCAAAGTTTTCTTCTTCACCGATATTCTCTCGGCCACCAAAATTTTTCTCGGCCCCGATTTTTTTTCCACAGATATTTTTCTCGGTCATATTTTTCTGCCATATTTTTTCTCGGCCCTCACCAATTTTTTTCTCGGCCTCGGAGTTTTTCGTGGCCATCTATATTTTCATCTGCCGTCTATATTTTCTAGGCCACCAATTTTTTTCTCGGTCTCCGATACTTTCTCGGCTACCAACTTTTTCTCGGCCACCAACTTTTTCTTGGCCACAGATATTTTTCTCGATTAATTTTTGACGGCCACCGAAATTTTATGGTCACGATATTTCACGGCCATTGATATTCTTTTTGCACGGTGATACTTTCTCGGCCACAAATATTTTCTCGGCCACCGAATTTTTTCGCGGTCCTATAAATTTTCTCGGCCTCAGCAATCGATATTTTTCTGTCTAGTTTTTTTTTGGCGGCCGTGACCTCCAAAGAATTACAAAAATAAACGATACATCTCATATTTTGTGCAACCTCAAGTACCCCCCCCCCCCCCCCTATATATATTGTTACAGAAGCCCCAAAAGCTCGCGCATTCCGATTCGGTGCGGCACCGAAGGAGTCTATGATGTTTCGATGTCCGAAACGCGTGCAAACGAAGGGTTCAGGAACGGCATGAGGCAGGACGGTGCCAATTTTCATGCGAGAACTGTGCCTACTCTTGCAATTTCTGTTGATTTTTTTGGTAGCACGTGGCACTTCTTATTTTCTGTATATCCATTTTGTCTTCTACATACAGGAATATATATATATATAGGATATGTTTAAAAACCTAAAACCTAAAAAAAAACCAACCTAATACAGTGTTCGACGAGCGTCCCCCGCCGCCGGCGGACACTCATTATTTGCATTGTGCTCACCGTGAGGTCGCGCGGGAGCCCCGGTGATGAGCATCTCTTTACGATGTCCACACGAATAATACAATAACACGGGCTCCTCTTCAAATATGACAAAATGTCTTTGGCGTTCTCTCCTGACTTGGAGCTTCTGGGTCTTCGACCCGTTCTTGTCTGTGAGGCGAGATGCGATTACCCTCTATATTATTTTTGGAGATTTTTTGGTTTTCTAGGGGCTGCGCCATTCATAATACAGATGATAATGCCGGCTATCATAATAAGTCCACAAAAGTACCCATATGGCCTTGAAGGAAAACTCTTCTTCACTCTTGGCGTGGGGACATTTGGTTGTCTGTGCTAGGTTTGATGCTGAACATGGTAATTTAAATTTCCGAGGCCATTGTATATGTTTTCTTCTAGGCTACGACATACAATTTTTTAGGCCACAAAATATTTTTTTTTAATTGTATAAAAACGGAATGTTCCATAAATTATCTATTTTTGAATTACAGTTAGTCTGAAAATTTTTTTCAAGGGCACCTGTCTAGGTCAAGAACGGATTTTTTACTGCCGGAGAACATAGGCATCAACTTTTTCTGCCACGATTAGACAGATGGAAGAGCTTTTCGTAAAAAAAGCTCGGCCTCCACCCCACCTAACCCGGCAAAAAACTTGCAGCTACAAACTAACGAATCAATCCGGAAACTGACGGAAGTAGGCGTGAGATATCTTCGAAGTCTGTAATCCCTCTCGATCTGGATTTCTGGCAGCCTCCTACGAATATCGGTTAGTGTGACTTAACCTCGTGATGCTAGCGTGCTCCATTTATAGTTTGGTCTACGTAGATCTACCAAAAATGCAGGTGAAGAGACGCTCTCAACTGATTCTGTATGGTTAAGAACGCTGACGTCACATTGTTTTTGGGAAAAAAATTTCCGCATTTGTAGATCAAATCGCGATGGGACAGTTTGCCACCACGTGCTTACCCAGGAAAATCTGAAATCGGTGTTCGAATTTTCAGGAGCTATCGTAGACTTGACAGTTGCTCCGCCGGATGCTCCAAGATGAAGGATTTAGAAGAAGGTCAGCTACATCGTGGCGGTTAATCATTTGTCGTTCGTTTGGTTTTTTCTAGGCCACGGCTATCTGTGACGTCACTAAACTAGTTTCCAGAGCAATCGAAAACGAGGGAGAAATTCTACAGTGTCACCCGAGAGTGTCGCTGGTTTTTCTGCATATTGCCGACAAGTCGGACAATGGAGGAGATACAAGCAGAAATGAAGCGGCTTAAGAAGGAATACCCGACCCCTTATCGATATCGGACAAAGTAACGTCCGTATAATCGTACGCTTTTGGTGATGGAAGGTAAGACATGCGAACGCGATCTATTGGGTGGGCGTGGTCACGTCCATTTGCAAAGTGGGCGCACGGTTCCTTTACAGTGGACGCCAGCTTTTGAAGTTTTGAGTAATTTTTATGGGAATTGCTACGATAAATTCATTTAAAAAAAACCCAAGAATACTTTTAAAGTCGTAACGAAAAAAAACAACCGTGCGCACGTCTTGCAATAAGTTAGGGCGCCCTAAATTTTAAAAACGAAGGAATTTCATTATTTCTAACGCTCCAAACTCATTTTCACTACAAAGAACACGCCTCCTGGGAAAGCCCTTACTCATTTGCTGGATATATGACGTCACTAAATTAGTAGAGTGAAACCAGGTGCGCTCCATTGTACTACGCACACCGACGTGGTGTCAAACAGTGTCCCATTTCTGTGTGATCTTCCATAAATGCGATCGGATTTCTAAACAGATGGCGTTCGCATGGTTAAGAGCGTGCTGACGTCACAAACTTTTCTCTGCAAGAAATCATTTTTTGTAGATAACACTAAAATGGCACTTTGACGCCACGAACCTGCGCTCTCACTTTCAACACTCCCATTAAGCATTTCATGTACGCGCCAAAACGCACGGATTTCTGGCTCCCATTTACATAAATTGAAATTTTGAAAAAGAGTGTGCCGAACTAGGTCATTTTGGCTCGGCCATATGTGGTGAGATTTTCACCGCGTTGCGTGTCGCGTCGCGGCTCAATTTAAGTTGTAAATCTGAATGTGTTTGTCCGTGTGGAGTACCCGACTATTCCACGCGTTGCCCGGAATGCTATTGTGGATGGAGCACGAACATGAAAATTCAATAGAAGGCCAGAACCCCCTGAAAACGCCTGCCGCGCCCCCGCCTGCCTTGCAGCGCGGAACCCAAAAAGTGTTCACGGCCGCGGCGAAAGGCCCTCGACACTATGTGGTGTTAATACCTAGCTATTGACGCCTTAGTGTAAAACAAACATGAGATAACCGGAGAACGAAACCCCCTCGGGTCGACAATCTCCATGTGGATTGACGCTGGAATTCATGCTCGAGAATGGATTGCTACCCGGCGCCCGCAATGTACATTGGAGCTTCTCCTCGGGTATGAAAACGACGCGACGGTGGCTAAGCTGATGGACCATATCGATATTTGTGTTATATTCTACCTGTGATGAACCCAAATGGGGCCATATGAGTATTCCAGACCTGCGAAAAGGTTGGTTTTTGAACCTTACAAAAGCCTTAAAACTAGTGTTACTATTTCAGAACCGCATGGGAGGAAAAACCGGAGCCCCGCGATGCGCCTGGCAAACGTATGCTGCTGTGGAATCGACCTCATCAGGAACTTCGATTGGTTCTCCTGATAAGTCACGTGGTCTGAGAAAGTCTCATTGAATTGATCTACAAAAAATGCGGGAATTTTTTGTTGATCGAAGCGAACTGGGACTTCCTGCTCTAGTCGTAGTTAGCTCAATTACACCTTAAAAAGTAACTTAATCTTAAAAATTTCCAGCCACCGCTTGTTCGGGATCCGTCACGACACCTAGTTTTTCACGGCCCGGCGGCCTTCCCGGAGCCTGAATCACAAGCTGTCAGGGATTTCCAGACCTGGAGCAAAACACACCCGTTCATCTCGCTGCATTCCTACTCCCAAATGTGGTTGATACGCCATATGGACATCAGAAAACAGAGTTATCCACAAGACTACCATACTGGACGGCGGCCATAGGCTCTGCGAGTAACTAAGGCGTTGTATTGTATGGGACGAAATATCAAGTCGGGACCGGCGCTGATTTGATGTGTAAGTAATATCCTTTTTTTCCAATTTTTAAATTTCTAAGGATTTCAAGCAATTTTCAAATTTTGAAAATTAAAAAAACAATTTTTTTCGGAATGTTTTAAAATTAAAAAAGAAATTTTTTTAATAGATATTTTAAAGTTTTTTTTTGGAAAATTTTGGATTTCTGAATGGCGTAATTTTCTTTTCAGCTAACTGGATGAGATTAGTAAAGATTTTTTTAGGACTTTTTAATTTAGACATTTCCGGAAAAATTTTTAAATTATTAAAATTTCGAACTTTTTCGATATTTTCGGATTTTTTTGCAACCATGGTGAATTTTATTTTTTTGGATTTATTGGAATCACTAGGAGGTGGGCAGCAAGATTTTTTCCGGCAAATCGGCAAATCGCGCAATTTGCCGGAATTTAAAATTCCCGCCAAATCGACAAGTGCCGATTGAAAATTTCTGGCAAAACGGCAAATCGGCAAATTGCCGGAATTGAAAATTTCTGGCAGACCGGCAAACATGCTAATTGCCGATTTGCCGAATTTATCGATAAATCAGTTGCCAAACGGCAATTTCCCCCACCCATTAATGGGATCTTTGAAATAAAACATGAAGAAATTTTAAATTGTTGGAGTTGAATTTTGTATTTTTCGGGAATTTTAATAAAAAAACGCTGAAAATTCTAAATTTTGTAACAAAGTTATTTGTGATTTAAAAAAACATTTTTTGGACTTTTCTGAAATTTCACGGATTTCTGGCATCTCTCATAAATTGAAATGTGACGAAGAGTTTTTGCCGAACTTGGCTATTTTGGCTCTGCCATATCTGGGATGGACGGCGCGCTTCATGTCGCGTCGCGGCTCGTAAAACTAAATGCACTTGTCCGTGTGGAGAGAAAATTCAATGAGGAAGGCCAGAACCCCGGATTTTTGAAATTTTGAAGTTCTGAGAAACCTGTGAAAGACTCCTACCTAAACCTGAAGAATTTGAGACGAAGCTTCTGGAGATCACATGATTTGGCTAAGGGGAGCAGCTTAAGGTCCCCTATGCCTACCTGATTGAGCTCCGACCAAAGAACACCATGATTGGGTAAGCGATGGATCCTATCAAAAATATTTCATTCTAGCCACGGCTTCCTTCTCCCCGAACGAGAAATTGTGCCCACTGGACTAAACCTTCTAATCCATCAAAGTGGTTTATGTGCCGACGAGCTTGTGGCGCATAATTTGTGGATCCTGTGATTCGTATTGAACCAAGCTGACCACAACTACCACAAAGCCCGCAATTCCCACCGTATCGGTGTGTGGATGGTCACTCTATAATCGACACCAACTATGGCGGTCGGAGCTTACACAGAAGCCTACGGAAGCTCCAACCAGGCACCACCACTACTACGAAAACCTACTACTACCACAACGACCGAGGAGCCTACCGAAGCCCCAACAGAACCCAGTCCGACTACTGTCGAGGCCACCGAGGCTTCTACAACTACAACGAGAACCTTCCACATGCTCTGATACAAGTACCACAGAGAATTCTGAGGAGTACCAACCAGAAGACATCCACACCAGGGGCACCTGAAGCAAGCACCAAAGTGAAGAGGATGGTTTTTGAGTCTCAGGCTTAGGCCTATGGCTTAAACTTAGCCTTTCTTAGACTGAGGTTTAGGAGCTTAGGCTTCAGCTTAGGCTTAAACTTAGTTTTAACTTAGGCTGTGGCGTAGTCTTAGACTTAGTTTTGAAGGCTTAGAGCTTAGGCTCAGACCTCGGCTTAGGCGTAGGCTTAGAATAAGGCTTAGCTGTTTTAGGCTTAGACTTAGTCTTGGGCTTAAGCTTCGGCTTAGGCTGTCTTAAGCTTAGGCTTAGGGATGCTTGCACTTGGGCTTGGCTTCATTGGCGAGCGTGAGCTATTTAGGGTTTTATGGGAACTTCCGCACCTTTAGACTTAGGCTGAGGTTTAGGCTTAGGCTTCGGCTTAAGCGTTCTTAGGCTTATGCTTAAGCTTAGGCTTGGACTTAGGCTCATACTTGGGCTTAGGCTTAGGCTTGCACTTGGGCTTAGGCTTACTTATGCTTAGTTTTAGGCTTAGATTTAGGTTCAGGCTTAGGCTTATCCGTACCTATGCAAATACATTTTCTGGCACAACTGATAGTTGCCAGCGACCTATTTTAACTTCGAAATTCCCACGAACCATTCCAGGAAACAATCACACCGATCAAACTGCGTCGACTACGGTGACTGCCACTGTCGTCTTTGGCACTGGGGGTCTTTCAGCTCTGCTATCGGATCAGGTCCAAGTTGTGCCCCAAAGACTTGCGACTCGCGGTGCTCTTTTTCGGTGTGAGGCGCACGCTGGAAACTATCGTATGACAAATTGTCAATGTATTGTATAAATGATTTCCAACTTTCGTAATTGTGGACTAAAAACTACGTTATATTTTTCATGCCTGACTGCGTGGCAGCGTGTCAGCGCCCGACATTTTCTGAGTTCCACGACGGGATCCTGGCAGGCGTAGGCGTTGCAATTTTGACTCATCAAATTGCTTGGAATAATTAAGTACTGCTACAAATGATGTCACTAGCTACAAACTACAACTAGGAATTTCACACTACAAACTACAAACTACAATCTTAGCTCTTCAAGCTATGAAATACAAACTAAGAAATTTTTATTTTGCAATATTTTTTAAACGAGGTGTAATTTGGGTATAGTAAAAACTGGAATGACAAAAGCAAATCACAAACGACAAACTAGAAACTAAAAGCGGAAACTGCAAACCAACTACAAACCACATACTACAAACACAAACTACAAAAATTACGAAGTACACTACAAGCTACAAACTACTGAACTCTGAATAAAGTTGAACGTTTTTTTTGGTGCAATGATTGGCGTATGAATTGCGAAATAAGTGGTTAAACACATACTACAAACTACTACAAACTACAAACTAGAACGATCCTAGAAACTACAAACTACAAACTACAAAATATATTACAACCTTAGAAATTTTGAATTTTTAAATATTTGTGGAACAATCAGTTTTAATTATTCGACGACTAAAGTCAAAGCTGAAATCATAAAATGCTAACCACAAACTACCAACTAAACTACAAACGGCAAACTACAAGCTACAAATCACTGAACTCTAATAGAATTTGAAAGTGTACTCATGGTTTGTGCCATTACTGGACGTATGAATTACGAAACCATAAGTTTTTAGTGACCCACTACGAACTATAAATTTCAGAAAACTACAAACTACTAATGAATGTAACTACAAACTACAAACTGGAACAACAGCAAACTACAACCTACAAACTACAAGCTACAAACGCTTATATATGATTATTCGATTTTAGTTATTTCCTGTTTTTTATTCTTTTCCAAATTCTCAAACTCTACTGAAATAAAAATACCTCACACAAATGTTTCTCATCATGCATCACTGACTAATTATTTTCCAATAAACATAGCGTTTTGAAAAAGTATGGAAACAAAAAATGGAAATCAAAGGCGGAAATATGCATTTTTCTTACTCATTTTCTTGAAATTGGCTTCATGTGATTGGACTTTTTGATTTTTTGTTGGCCTTGTTAAAAACGTGGTAGGCAGGCATTCATGCCTACGTCGAGTGCCTGCCTACCAGTCGAATTCGAACCCGCAAGATGTCGGCCGCTCCCTTCGATTTTGGAAGATTTTACTTATTCCTCTTCTGCTAACATATTAGACAATTATTTTTCAACCCGTGTACACAATAGGGCGGCTAAAAATTAGGTTGGAAGATAGAGGTGTACAGGAAACGTTTATAAGCTCTTTATGCGCTTACTACTGAGTACCACTTATTTGCCAATGCATTTTGTTTCTCAACAAGTTGGAGATTCCAGAACAACCAAGGTTTGGCGGGGCTTACTTTGAGGCAATTTTGCGACTGTACAGTAGATTCATATGTGCGAATTTAAGTAGACTTTGAAAACATTTAGGCGGGAATTCAAACATTTATTTTTAAAACCATCTTGGCGGCGTGATCAAAGTTTTCTAGTTTTTCGAAAACACTTTGGCGGGAATTCAAAATGTTAATTAGTCTTAACTTCCTGAATGCTCTAGATCAACCTTCTGGAATATTTTAGAAAACTCTAGAATGAGAACCTTCTGAAAAATTCGAAACAAGTCTAGAATGTTCTGCAGAGCCTTTTGGACAAGGCTTTTCGAAAAAAATCTGGAATAGACTTTTGGAAATTTTGAGAAAGTTCTGGAATGTTTTGGAACCTTCTGGAAAATTCGAGAAAATTCTGGAATGTTCTAGAACCTTGGAAAATTTGAGAAAATTCTGGAATGTTGTCGACCCTTTGGAAATCCGCGACTGGAATGTTGTGGAACCTTCTGGGAAATTTTTAGGGGAACAATCCTGGAATTCTCGATAGCTTCTGGAATTGAGAAAATTCTTGTCACCAACGTTTTGTGAAAAAATTTAGCTGGAAACTAAATAATTTGAGAATTCAAACTTTAATTTTTCCAATTTTTTCGGATTTTTTTTTTAGCTTTTAAGCTTTTTACATTTTCCATAAATTTTAGATTTCAAAAACAAAGCTTAAATTGGCAAAGTTTTGACCAAATTTTTTGGCTTTATAGCATACAAAAGGTTGAAAAAGTCCACAAGGTTCTTGCTCCACACAGTCCCCAAAAACACATCAATTTGGTGGAAATTCAAATCATGTTTTTTTTTCAAAAAATGTAATGGCCTAGAAAATATTTCAGATTCAAAGCAGTAAGGCCGTCAATCCTACCTCCGTTCAATCCGTAAAATACCTAAAAATCAATCCCCAGGAATTAGTCTCATCAAGAAAGAAAAGAGCTCTGCTTGTGCCCACTCCTCATCTCTTCTCATTTATTTGTTTGCAATTAAACACATCCTACTCAGACTGCATAACGAAGGAAACAAAAAACGAAAGAATAACGAAATCCCAGAGCATATTTCCTTTATTAACCCTATTCATTATTTTTGTATTCAGGTGGAACAAAAAACCGGCTCGGCGGGTTTATCTGTCTGTAAATCTTCTACACGCCTACCTACAGCGGCCTGCCTGACTGACTATGTGCCTAGTGTTTTTTGTCCTTTTCGGTTGGTTTTTTTGAAAAATTTTTTTTCCTGATTTTTTTTGTCGTTTTTCCATTTTTCTGAATTTTTAGGAATTTATGTAAGTTTCTCTTTTTTCTCCCCCCCGCCGGAGCCTAAGCATAAGCCTAAGTACGCCTAATGGTGCCTAAGCCTAAGCCTAAGCCTAGGCCTCAGCTTAAGCCTAAGCCTAAGCCTAAGCCTAAGAGGCCTAAGCCTAAGTCTAAGCCTAAGACTGAGCTTAGGCTTAAGCCAAAGCCTTAAGCCTACTCCTATGCCTGCGCCAAAGCCTAAGTAAGCCTAGGCCTAGTCTAAAATAAGCTCGGCCCCTTTCTGGGCCAAAATTTGTACATGTACCTCCTAAAATTGTTTCATCGTTAATAGCCATAAAAACTAGGAAAAATCTATTTCAAATTCTGAATGTCAAAGATAAAAATTCACAGAAGTGCGGGAAATTTGACCTCACCAGAAATGGGGCGGAGCCCATTTTTGGATAGGCTCCACCTCTTTCTAGGTTCTCTAAAATCAAATTTAGCTGTCAACTTTCCTGGTAAGCTTTAGTGGTTTCATTTTTTGTATTCATCACATTTCTTTTTCATTTTTTACATTTTTTCATAATTAATTTTGATCTACTTGTTTAACTTGACCCTGCCCCCCAATCTCCTCAAAGTAATGGGAGGAGTCTAAACAAGGTAGATCAAAAATAAATAGAAAATGAGAAAAATTTGCCATCGTGTTTTTCGATAACACTACAGTTTAATCATACAATAATCCCACAACTTAAAATTCAGCAAATAACCAGGAAATGGGCGTGGCTTAGATTTTCAAGGTTTCGCTGTTTTTTCCAAGTTGTTTCTGATATGAACCGGCCCCGACAAAAAATGCCACAAAAGTCGTAGTAGTGATGTGTGACGTCTGTTCTGATGACTAGAATTCATATTATAAAGGTCGAAAAATCCCTTCCGAACGAACCCCCCAAGATCATCCTAACATCCCAGATTTCTTCACCCGCCCGCTCATATAGCTTTACCCACCTAATCTTTTTGCTTATTTCTCAATCTCCGTCTTTCTTGCGTTTTTAATTAATTCAAGGAATCAAGCAGTTGTGGTTAATGGCTATGAATTGCTTTTTTATTGATATCTTTAATTATTATTTATTTAGTATCTAGCCATGTACATGTGTTGAGTCGAATAACCTGAAAATTTTGTGCCAAGTTATGAAGGCGGGGTCTTTCATACATTTTTTAAATTGTTTTTTGGCTAAAATTGTATGTATTTTGAAAGTTGTGTGTGTTTTCCATTTTCTTTAAAAAAACATCAAAAAAAAAAATTGGTATGTAGTAACGTAGGTAGGCAAGAAGTAGTTGTGTAGGTAGAGACTTGAAAATAGCAGCTATGAATAGGTGCGGTACTTTTGTAGTTTAGGCAGGTTCGTAGGCAGATAGGTGAGTAGAAAAATCATTCAGAAGACATTCGGCCAGGTAGGATCACTGGTAAACAGGCATAATGTAGACGTACGTAGGTTAACACTTACGTACGAGGCAGTAGGCATCAGGGCTTTGTGGCAACCGGCAACCGGCAACCAAAAACCAGGTTGCCGGTTACGGAAAAATTGCCGAAATTTCAGCAACCAAAAGGTGCTCGCCCGAATTTTCTCGAATTTTCCAAAAGGTTCTAGAACATTCCAGTTCTCGAATTTTCCAAGAAGTTCTAGAACATACCTAACTTTTCTTGTCGAAGTTTCCAAAAGACCCATTCTAGACGCAACATTCCAGAAAATGATATTCTCCGAATCTTTGCCTCAGACTAGAACATTCCTGAATTTCGTCTCGAATTTTCCAAAAGGTTCTAGAACATTTCAGCATTTTCTCAAATTTTCCAAAAGGTTCTAGAACATTCCAGAATTTTCTCCAAGTTCCCAAAAGATGCTAGAACATTCCAGAATATTCTCGAATTTTTCAGAAGGCTCTACGATGAATATTCCAGAATTTGCTCGAATTTTCCAAAAAGTTCTAGAACAAGTTGCATTTTCAGCGTACGGCAACTTTACTCAGCAATTGCGGGTTGGCATGTAGTCGCAGGCAGGCATGTTAGTAGCGCAGTTTTGACAGTTTTGAAGTTAACAATCCTACCTGCGATGCACAAGAAAATGCGCGGCAGTTGCGGACCGGCAATTCTACCAAATGAGCTAGACGGTAGGGCATGTTCTTCCGAGTATTTTTTAAAAAAATTTGGCAAAAGTATAGCATGCATAAATCTTTGTTTTATTTGAAAGTTTTATTGGCTAGGAACAACCGAAAAAGTACTCAAAAATTGTCGGAATCTTGAAAATGTGAAAATTTCCAACATTTCGACTATTACTGGAGATTTTTACAATTTAGTCTATTAAAAAAAAACAGTTTACTTTCAAATAAAGCAAATTTTTCTATATTGTGTGATAAAATTTTAATGAAAAATAGGGGAACATGCCCAACCGTCTCATTTTGCCTAGAATTGCCGCGCACCGTGTTAGTTTATCCCCGTAAACCTCCAAGCAATATGGCAGGAGTCCTTCCGTCCGTCCAAAACGTCATAAAAACTCGTTGGAGATGGCAAAATTGGAGATGTGCCAAGTTTGCTGGAGAGGTGGGGGGAAGGAGACAATCATGTTGTCTGCGTACCTGAGGCCAGACTCGTCTTGTTATCTCTCTGTACCTACCTGGCAAATGGGACCTCCCCAGACCGGTGAGTTTGTCCTTTCAACACCTATTGTTTCTGTTGGTTTGATACCTTTTTTTCAACGCTACTTTGCGGGAATTTAGACTGATTTCTCATGGTTAGAAACGTGCTGACGTCACATTTTTCGCGGGAAAAAAAACCCACATTTTTTGTAGATCAAACCGTAATTGGCTAGCCATTCCAACAATTCACTGTTTTTTTTCTGAACAAGTCGAAGTTTTGAGTTCCGCACACGCAATTCTGTCTCTGATAAGTTTGGAAGTTTCAAATAGAAACCTCTCAATTGTCGGACCAGCGCGCTACTTCATCATACCCCGCAAATTGAACTGCTCGCGGCAAAATTTAAAAATTGATGCTTCTCCATAAACATACCAAAACTACCTAAGACTGAACTTCATTATCTTCTTTTAAACTTAAACATTACCTTAAACGAAAAAACGTTTGTACGAGTCAGAGTGTCTCATTTCATTTCGATCTTCATTGATCTACAAAGAATGCGGGAGAAGAGGCGCAGAGTTTTCAACTACTTTCGCATGGTGAACGTGCTGACGTCACATTTTTTAAGAAATTCCCGCATTTTTTGTAGATCAAACCAGCCATGTTGGCAGTCCACGTGGCCGGCGTTTGTAATCGTTCAGTAGGTAGGTAGACACAGGTCAGTAGGCATAGGTAGGCGGTCGGTCTGAGGTAGGATGTTGTTGACCATCATCCAACGTAGCAAAACATGCTTGACGACTAGCCTCAGGATAATCACAAAGTTCTACGTAGTTATGATTTCAAGCAATGAGCACATTATATCACTGACTAAGCCACAGCTATAAGACCCTCCTCCGAGTATATTCTGAGGATCACCAAACATCTAGACGTAGGTTTGCAGTCTTTCTGTTGGAACATTAACGAGAGTAAATCTCATCTGTTAGGCAAACGACCAATTTCAAGTTCAAAACTATAAATATAAATAAAGCTAGTAATTGAGCCAGTCCTACTTCAAATTTCCCACAAGTTCATTACAAACCGTCCAATTCCCAAGCCCATGTACTCCCACTAATCAGTTTCTATCCTTGCCGCCCAACTTTCCAAATTCATTTATCCGCTTTGCATAGTTTTCGGTAATCTTGACGATTTTCAGAGGTTGAATTTTTTATTTTTTCCAAGAGTTACGCAATGCCAAAATAAATTTTTTTTTGTATTCTCAACAGAAAATTGCTAAATTTGTCCAACTTCCCATTTCTCGGAATTTGACGTAATCAGTTTTTTGAATTTTTTTGAAATTACTGATTATCAAATTTTGTTGGAAAGTTTATTCCTTTAACCTACACAGCTACCATATTCTGTCTAGGTGCTTACCTACACGCCTGCTTCGTGCCTACCCGCATACCTGCAGCTGGTTTATCTTCAAAAAGTGCAAAGAGCCAAAAGTTTCGAATTGACAAAATACGTGCTAATTGTTTGGAGCAAATTTTGCAACATGCCAAAGTTATCAAATTTCCGCATAATTCCAAAATGGCAGCCCGACATCATGTGCCTACATTCCTGTGGTCTGTAGGCCTGACAAAATGTCCATCAATGTATGTACCTATTTCATACTTATCTACCCGTATAAACATAGTTCATCTCTACCTCAAACAGCATGTTACAGGCTTTCTTCTCTCCTACCTACCTACCTTCATTAACTGCTCTGTTTATTGACTACGGCTGCCTACCTTTAGCATGCCTGGCATGCCTTCATACCTACCTCATTTATCAGATCCTTATAAAGCGTATGTACAAGTTCGCCTACCTATTGTGTTAATAACGATCACCGTCTCTAGGCTAACCTGCCTAATTGTGTCTACCTACTTAGCTATCTCATGCCTGCCTACTAACCAGCTCAAGTACCTACTTCATGCCTACCGGCCTACGTTCCTAACAACGTGCCTACCTGCCTGCTCACTAGCCTAAGTGTCTGCCTACATGAATTGTTCGTTAGCACACCAGACTTATCATATATACAAAACATAAAAAGAAGATAAACAATAATAACAAGTGGGTAACTCAAAAATGAAATTGGTTTATCTCCCTGCTCCGAGAGCACCAGCACTTTGGTTTAGATTCCGTCACTACAACTTCAAATTTTGCTTTGTTCGAAGGACCTTTTCCTGATACATACTAATTTTTTCGGATCCGGTTGGCTCTGGATTTCAAGTTTTATAATAACTTGGGCTCCCAGTGACGTCATCAGTGGAAGGTGCAATTTTAGTAACTAGACAGCTTGCTCCTAGTTTACTGCTCCTCTTCTCAACGCCATGAAATAAGCCAGAGAGAGAGAGACCCCTCATCGAAAATTAAATTAATCGCTAAAACGTAGGTAGGAAAGAGAGTGGGAGGGAGACTCCAAAAAAAGAGTCAGGGGGGCTCTCTCTCTATCTCTCTCTCTTCGAGCGGCAAATCCGCTTTCAAATTCATTCAAAAATATGTGCGCAACCACCACCACTACCACCGGCTCCAGGTGGTAATTACACTTGAAAACCAAGTACTGGTTTTCGTGGCCGGGCAACTTTTAAGACCCCGGTGGAATTTTGTAGGTCTATTTAAAAAATTGCAATTGCGCTTTTTTGTACTGTTTTTTTTGACACAACAACTTTGAAGCTTCATGTAAAGCTGGAACAGCGCTCTAATGACAATTTTGACTGCATACTCGCACTGTTGATAAATGGTCCGTGTACTCCACGGGGGCAATTAAACTGGATTTTTTTCGATTAAATAATATCTTGATTTTTTGCAGTTTTGGCTTAGGCTTAGCGAGGCGTAGGCTTAGGTTTAGTTTTTTCTCGGGCTTAGGCTTATGGTGAGGGTCAGGCTTAGGCATAGGCTTGGGCTTAGGCTTCGGCTTAGACTTAGGCTTAGGCTTAGCCAGGCTTTTGTCTTAGGGGAGCCTTAGGCTAGTTGTAGGCTTAGGCCTGAGGCTTAGGGGCTTAGGCTTCCCTAAGGCTTAGGTTTAGATTTAGACTTGGGATTTAAAAAAGGGGCTTAGGCTTAGGCTTAGGCTCATACACAGGCTTAGGCTCAGACTTAGGCTTAGACTTAGGAGGCTTTGGCTTAGTCTTAGGGATCTTAGGCTTAGTGGACTTAGGCTTAGGCTCAAGCTTAAGTTCAGGCTTAGGTTTCGGCTTAGTCTGAATATTTGGCTTAGCCTTGGGCTTAGGTTTAGGGAGGGCTTAGGATTAGGCTTTGGCTTGCCGGCCACCTAGAATGTGGTTTGACAGCGGTAGGCTATCCAAATTCTAAAAAAATCGGCTACATAATTAATACTTAGATGGGCCTATAAACCATTTCTCTAGGCCATCCTGCGAAATTACCAAGACAAAAAATTTCAGCCGCTAGGGGAATAGAGTTTCCGTTTTCCAAGGCCACCTCAAATTTACCACAGTCATATGTAAGGTATCGGAGGGCACTGTAGAAAATTCAGTATCAAAAATCAGCGAAGTAAGCATTAAGAAAGTTTTTTGTGTGTGTGTGTTTTTTGTGGGAGAAAACATTTCCCCTCTCTTTCCTGCCTGCTCATTTGGATACCACCGCTAACCCATCTTGACTTTGATTACCCATTTCCGTCCCCCTTCTTCGTCTTCTTCTACCCGGGATAGAGAGAGAGCTCTATATATTTTCGTGTTCTTGATCTGTTACCGCGCATTGAATTTGTTTGAGCTGCCGCCGGCGAATATATACATGCATGTCTAATTTTTTAAGTAACTGGAAAATCTAGGAATTTTAACGTAATTTGGTTATAAGCGTACAGATCGGCCCATGCTGGTGATTGTACGAAATTTTAATTTCATAGTGTCTGCAGAGAAGCTAGGCATATCCACAAGCCCCTACGTGGCCGTCAAAATTGAAAACTAGGCGATTTTTTCTCGGACTTTTTATCTACTTTTATTAGGCCCTGTCTTCTTTTTTGCAACGTTTTTCTACTAGGTCACCAAATTGTTCTACGCCAAGCTGCCTAAAACTCGGCCACCGATTTTTATTTGCGTCGGTCTGTAACATTCAGTCTCCGACCAGCTCGACTTTTGCTACCTGGTCGCCAATGTTTCGTAAGCGACATCGAAAATGGCACTCGCTGTGACATTTGTACTTTTTTTCACCCGGCCTAGAAATTTTGAAAAAAACTCGGGCACTGATTTTATCGGCCTTGGAATCCTAGTGTAACTTTGTGGCATGATTTTTTATTTATTGTCCATCCAGTTTTTCGTCTGAAAATTACAAAATGTTTTAGTGACCGTTGAAGCAAAAACTCGGTCACCAATTTCCCGGCCAAGTTACTACGGGATTGTACCGTCTCTACCATATTTCTGTCTCAAAACATACTCTCCTTCCGTGCTGCCTACGTGGCCGCTCAAGTAGAAAACTCGGCCATCATTTATTTTCTAGGCCATGGCGAAAATATGTAAAATAGGCAAAGAATAAGCGTGGTGGTTAAAGTAATTTTGGGAAATGGATTTTAAAGGCACAAGTTGAAAAAATAAATCAGATGAAGCTAAATACACGCATAAACCTTAAATAGGCCATCAATTTTTTTCTCGGCCAGGTTCAATCTACAGGTAACCGTCATGTTTCTTGCTCAAATTTACACCCTATTCTCGAAAAATTTTTTTTACGTTGAGTATGCTCTCCTGCCTAACTCGGCAGTGGCCGCAATTAGAAAACTCCCGGCCACCCATTTTTTCCCGCTAGGTCATGTCGAAAATGCGTAGGCGATGTAATGGGGTAGTTCAAGGTTGCGTAATGAATAACCTGGAACCAAAAATGTTGTCAATATATGGCCGCCAAAAAAGAGAAAACTCGGCCAACAATTTTTTCTCGCCCAGGTAGGCTACCAATGAACGCTACGGGAACCGTCCCTATCTCAGGCTCAAAATTACGCCTTTTTTCTCGAAAAATTTTTGCATGCACTCACCTCCCGTGATTCTTAATTAATGTAAGACGTTCTTTTTTCTCTTCGTCTAACGTGTGTATATGCAGAATTCAGGATACTTGGTGCGTCTTCCTTTCGGAGTTCTTGTCTTCTAAGCGAAAAAAACGTCAAATCTCTGTGTGCGTTGTCATCGGAAGACTCGCCTTCGAAGAAGACGCTTATTAGCTCATTTCATCCACTCGCAAATGCTTCATTAATTTTGTGCTTCTTCGCCTGCCTTCCGACGTGTTTACTCACACCACCACAACCACCACTCCGTACCTCCTCACTCACCGTGGAGAAACAGGTTCTGGATTGTTTTGTAAGCTTTTGAGTTTTGTGTCCTAACTCACTTTTTAAGCTCCGCCCACTTCTTGGCCTGTTCGGTTTATTAGAATTTGTGTGGTGTACTACCATCTGAAATTCGATCCGAAAAATGGCAAAAAAAATTCAGCTGACTGATTTTTTTGAACTTTCAAAGGTTCAGTTTTTGCAACCTAAACCTCTCTTAACATTAACTTTTCAAACCCCGCCCAAATCTTCTTTTTCCAGAAATCCACCAGTAATTTTTTGGGCAATTTATGGTACAAAGCTATCAGAACAATTTTTACCGAAGTTTTTTTATTTATTTTAATTAAGTCTACTGAAATTCCTAATATATATTGAAAAATGCTTTGGATGATCCCGAAATTGGCCAAAAAACGTTGATCGATGGTTATTTTTTTGAACTTTCACAAAAGGTTCCGTTTTGTATTCAACCTTTAAACCCCCCCATTTCTTGGCTGTATTGTATTCAAAGTTAAAAGTTGTTCATGTTGTACTAAAATATGCAAGTAGCATAAAAAATTAATAACTTTTTAAGCTCCACCCATTTCTTGGTTTTTCTGGAAATCCTTCCTGACTACAGTAATTTTCTGGGACTGTTATGGTACATTTAGGTATCAGAAAAAAAGGATTCTTGGATTTATGTCCACTGAACTTGACCTGAAAATGTTTTGAGAATTCAACAATCTTAAATATTTTGATAAAGGTAGAATTTGTGTAAAACCCGCCCTTTTCTTGGCTGCCCAACCCAACTTTGCCCTTTGAAGATTTTCTAACTTCGGCCTGCTAAAATTCCAATTCTAGGCGATCTACCCTGATAAGAACTTACTCCTGAGTTATTGTTTGAAAAACATAGTCCATCCGTTGCCTAGAAATCCAAAACTAGGCCATCAGATTTTAGGTTCCTAGAATCACAAAGGCAGTTTTATGTTGTCAAATTTCAGTGGCATAACCTCATAATTTAGACCTATTCTATAAGGTCAGCCTATTTTTCTGGCCTAGAAATTTTCCTTGAGTTTGAGCCCCCTACCCCCACACCCACATGGCCTAGAAACCCAAGCCTAGGCCATGTGTCCCCGCATTCTCACTCACTTTTAATTTCTTAACCCACTTACACAATTCTCTCCCCCTTTTCCAATTTCGAGACATCGCGAACCTGGGAAAGCTCATTAGCTCATTTGTTGTGTGTGTGTGAGTAAGAAGCGGGGGGAAGGGGAGCCCCCCTTTTGAGTGGGCGGGGAGCTAGTATGGAAAAAGAGAGAAGGAGGAGAGCCATTTTGGATGGGTATGCAATGATTAGGAATCGAAATTAATTAAACAAACAACGGAATGAAAGGGGGGGGGATCACGGGCAATCGCCTGCCCTTCACTACATGTCCCCTGCTGGAAATGTGGAAATGTAAATTAACTGTAAATTAGAAAACTAGCAAAAAAGTGCGAACGTTTTTTATCGTCCTACTTGTTAATTAGTTTAAATTTCTATATATGTATGGTTAGACATGCCTATTTTGGCGTCTAAGGGTAGATGCGGGATACGGATACCATGGTTAAATGGGCGATGCATCATGCCAAATAGTAAATGCACCACTACACATTGAAAATTTAGCATTATATCCATATCACTGAAATTGTCCGGGGCCCAATCAATAGCCGCCGCCGACTTCTCAGGACTCCACGCGCCGTTATGTTTAATTCGCAGCGGGCGGAGACAGCTGGCCGCGCCCACAACGAGTTAAACCGCAGCGGCGCGCGGTACTCGTCAGATGTCGGCGGCCTGATATGATTTGGTTGGGTCCCGAATTTCAGTCTTTATTATTTGGAGTTCGCGTATAATGCTAAATTTTGTACCGTGTTAGGAATGGTCGATGCACCATGATAGTGCTAAATAGTCCAGCGTCTAGAAAACGTTGAGTACTGTTGAAACAGTGCAAAATAACAGTTCCGGAGGCGGATTCTAATTTCTTGAATTTTTTTTTTTCAAAAATTGTTTTAAAAGTAGCACTGTGAATTCCACCTCAAGCATTTTTGGTGTAAAGCAAATTTTTCACGCTCAAAATTTTGCGCAAATGGTTCTGAGGCTCCGTTGAAAGTGGATGCTCTTAATCAAGAAAGAAGTTAGTCCCGCCTATTGGAGGAACTGATCAAAACTGGGAGGAGCTTAAGAAGGTTATAAAATTTTGCTAATTAAAACACCCAGCTCCGCCCACTTATATATTAGTTGACTCCGCCCCACCCATTAAAAGTGGGCGGAGCTTAAAGATATTGACCACCTTTCTTGGGTGACAGTGCGTTTTAGCGTTTTTCATAGAGTAAATTTTCCGGCGGACCCCGGATCGATGCAGTCCCATGATTTGACGCGCAACGCCCGCTGGTAGTATGACGTCACTCGTGGCCGAACTCTTGCGGGGGAAACTTGTACTTACAGCAGTAAATTTCGGTGTCTCACGGAGCACCTGCACACGTACCGATCATGAGTGATGCTTCCCACCCAGACATACACATACACACAAACGTACTAATTAAGACAAATTATAGAACAAGTGGGGGGGGGAGGGGAGAAATTTACAAAAGTGTGCAGTGCGAGAGAACACACGTTAGAAGGAGAAGCTGCTCTGGGAGACGTGGGCATATCAGTTGGATTAGTTTACTGCTCTTTTCATGGGCAAATCAAGTGAGCTCCAAACATTTTGACTTTGATTGGGTTTGATTCTGAAATTTTTTTGTATATGGATATGCAGAAAAAATACGTTTCTTTTTTATTTTGGAATCGCACCAATACGCTGCGTTGCTACAGTGCAACTGAGCCGGTCGCATTTCTCTTCCATAACTTTTTTTCCTTCTAAATTATCAAAGATTAAAACTCATGCAAAAGCTCAATTTTATATCATTAAGGATTAGTAAAGTGTGGGTGATCGTCGAGGGGGATTACCATAATTCATTACTCATTTTTCAATTTTCAGCTGTGTTTTGTTTGATAACCTAGATGACCAACTAGTTTTCCCGTTACAGGGCTGGGACCAAAAAAAAAATTTGGACCAAAACACAAAAACAAAAAATTGAAGTTTTTCAAAAACCAAAACCAAAAAAAAACAAAAAAAAACAAAAGTATAATACCAAAAAATTTCTTATGCTTAAGTTGATTTTTAATGGGGTTAATCAAGTAATGTTGCAAAATGTATTAAAAAACACTATGACGTCACAACTGAGTTAAAATACATGTTTTAAAGTATTTTAATACATAATAGTTTTGCTCGAGTCGAGACTAGACATGGTGAACACTTTTTTGGATTTTTTTGGATTTTTTGGTCCCAATAAACCAAAAAAAACCAAAAAATCGATTTTTCGTCAAAATACCAAAACCGAAAACGACAAAAAAAAAAAACCACAAAATTCTCAGCCCTGGTTACCTGTCAGCAAATTTTCCCCTATCACCACTTCAGGAGTAATCAACACCCCAAAACGGCAATTATTTATTATTCTCCTCACCTCCTCAACACTCCATAGCGCCAGCCACCCTAATTTGATTGTTTAATTCGATTCAGGGCACCCCACCACACACAAATTTATTAATTTTTGGCTTTCTCGCCATTTTCCGTTAATATGCCCGGCTTGTGTTAGCTTTATTATAGAACTTTTTAAAGCGATTTCTTAGGAATTTGTGGGAAAACGTCATATGTGGCCTAGAAATTTGACGATCTCGGCCGTCGGGGTCGATGAACCATGTTGTGATGTATGAAAGGTGGCCTAGAAAATTTTAGGCCACCGTGATAGTCGTGGCCTAGAAATTCGGGCGCCTTCAGGTGGCCTAGTATGTGAAAAGTGACGTGTGAGTTCTTTTGCCGGTACGGTCAGGCCAATTTTCCAAATCCTTCGGAATGCTTTTGTTTTAATTAAGGTCCGTCCATATTCTACAATTTTAGGATCCGCCCATATCTTGGTTAAACATTTTTTTTGTGCTTCCTTTTCTGGAATATTCATTCAATCCATCATTGTTCTCAAAATTTGATGCACCATGTACTATATCTGTGGCCTAGAAAGCGCGACGTCACTTATGGCCTAGAAAATTGGATCTTGAAATGGGAGAAAGTAAAAAAGTAACCAAAGCCCCCTTCTGGACGGTCGTGGCCTAGAAAGTTAGAAGAAGGAGGGGAGTAGGAGATCGATCCATGTACAGCTGCAGCATTTGACGACTCGACGGCGCGTAGCTTTGTCGCAGGCCACGGCCATAAAAAAATGTATGAGATCGATGCACCTTGTTCGCGGACTAGAAATCGAGAATGTGGCGCATGTCACGCATGGCCTAGTGACTTTTACGGTTCAGGCCGAAACATAGGACGTGTCCTAGAAGTCATTCTTAGTCCAAGACGCTACTAAAAACTCTCAAAAAAGGTGAGCCTATGTGCCAGCCTACTAATCTGCCTACATTCTTGCCTACCTGTTACTGCAATCACCATGTTGCACCTACAGTACCCCCTTCCGCCCCCGTAAAACTTTTTCAACACGGCTCACCCAAAAAGTGCAGAAAACACAAAAAAACCAAGCCCAATCTACAAAAGCTCATACCCATTCGTGCTTGGATTAACAAATGCGCCACCATTAAAATGATAATTAAGAGTGTGATCGAGACTATTGTTGAAATCTGATCGGATTAAAAAGCGACTGGTCCGCGAATGAGCTTTTCATGCAACTGATGAGCCATTTCCTGTGCATGTACACTGATGATAAATCTCCCGATTTTATCTTTTCCGAGACATACCAAGTAATCTCAATGTTCTTCATTAGTTTCTTCATTTCCCGATTCTGGAATTAGTTGCTTTGATTTATTAAAATCTGTCACACCTTATGTCCATAAATCGTGATTAAATTTTTTACAGTTTTTTTTAAATATAGAAATGTGATAACTTTCCAACCAGGCTGTCCCAATACAGTTTTGATCTACAAAAAATGCCGGAAGTTTTTGCCCAAAACTCTGAGACGTCGGCACGTTCTTAACCATACAAAATCAGCTGAGAACTCTGCGTCTCTTCTCCCGCATTTTTAGATCATCGTAATACAATAATGAGAGAAAAAAATTTGAAAAATGAAAAACCTATGCCAAAAATTTGGCATTTCCCTCGGATTTTTTTTTTCGAGCCTAAGTTTCGATAAATTCTAGATTTTTTGAAAAACTGTCTGAATTTTTTTTTTTGAGAACAATGATTATATTGATTAAAGATCAGTGTTTCATGTAGCGTAGAAAAGGTTAAAAAAAAGATATGGGCAGAGCCTAAAATTACAGAAATTGGACCGTAAAGTTTTCAAAAAACTTTTTTTTTTTCAAAAACCGAAATTTTATTTTAATTTCAAAATTTCCGCTTCGGGGTTTCTTGATTTTTTCAAGTTCAATTAATTTTTTAGATTTTTTCCCGTAAAAAACCCAAAATTTACTGAAGCTTCACTATTGGATTAAAAATTTATAAGGTTTTGCGGGAAAATTAGTAAAAAATCGAAAATATAATTTAAATCTGAGAAAAATCAAAAGTAATTACAAAAAATTAAGGCTTCCATGGAGCTAGGTTCGCGTGGTGCCAGGCTACCCATTATTTTTTGTTTTGTTTTTTCCCCAGGAAAGTGTGACGTCAGCACGTTCTTTATAACTATGCTCAGTTGAAAAGTCTGCCTCTCTTCTCCCGAATTTTTCGAAGATCATACCAAGATGGGGCATTTTGACGCCACGTGTAGACTGTAGGCCATAAACCGCCTGCCTTCCTGATTTTCAGGCTACCTCCGCCTGCCTGTCTTTTCGCCCCAATCCACTCCTTATGAATATCTAAAACACATTCAGGAAATTCCTTAATTTGATTTTCACCACAGTGATAAAAAAGATAAATTAAAAATCATTCTCGTCAAAATGCAAAAAGAGTCGTAAGGCAGGCAGGTTTCAGGCAGGCCCTGGCTCACGCGTGCCGACGAGGCAGGTTACTAAATTTCGAAAATACCTTATTTACTCTACAAATCCTCTTAATACCCCGACATTACATCAAACCTATTAATTTCTGCCTTAGGCGATGGGACTACTAATTGATAGGAAAAGACGACTTGTGTGTGTGTGTGTTGAATTATGATACAAATTTGATTTTAGGCAGGTCCTCTTTCGACAAAAAACTTGTGTCACCACCCCACACCTCCCACGTTTTCGGTCAGTGAAGCTTCTGCTCGCTGTTAAGCAGATATTCCTAGGGAAATCATAAATCCATTCAAGTACTCTTTATTTTCTTCTCTGCGACCAAATTAGTATACAGATGTCATCATACTTTTTTGTTTCTTTTTGTGGGGGCTGTTCATTACAGTTTGCTCTACAAACGGGAATTTATTTTGCTTTTTGCCCAAAAGAATGTGATGTCAGCACGGTTAGCCGTAACCATGCTCAGTGAACTCTGCGACTCTTCTCCCGCGTTTTTTGTAGATCTAGCATTCCTGTAGATCGAAGTGGGAAACTCTGACACCACGTGCTTTGCGAAAAAATTTGAAAAAAACCTTTCTTTAAAAATTTGGCATTTTCAGCTGGGTTTTTTTTCTCTACAAAATTTTTTTTTGAACGAAAAAATGTTTCGATAAAAAGGTTCTAGATTTTTTGAAACTGTCTGAAATTTTTTTTGAGAACAATGATGACTTGAATATTGTAGAGAAGCGTAAAAATAAGTAAAACCAAAAAAAAACGCCTTGGGCGAAGCCTAAAATTACAGAAATTCGACCATAATGAAAGTTCCCAATTTTTTCTTCACAACTTTTTTCAAAATTGCTGAAATAACCCAACTATTAACTTTAAATTTAAATTTCAGAAATCCTAATTTTGACGCCGATTTTTACAATTATAACCTGGATTTGTTTTTCCTGCAAATTCTTTTTTAGCAACTTACAGTTGGTCGGTTTGTCGATAGAGCGTGCTTATTCACCAGGCGCTACTTCCAGTTTGTTCTACAACAGTGCGGGACTTTTGCTTTTTGTCCAAAAGACTGTGATATCAGCACGTTCGTAACCATGCAACAATCAGTTCCGCATTTTTTGTAGATCAACGTTGATCAAAATGGGGCACTGAGACGCTTTGGGGGGCGTAGCGGGCCCTTTCTCATTCCCGAAAGTGCTCTCTGTTATGAGGTCTCCGTCCACGCTTTATGGATTCAACTTTGTACAGTTCACACGAGCACCCACGACATGATTATTCATACAACATTATACAGAACTAACTATTCGAATCTCAACATGTCTTCTTGCCGAAGGGTTTTTTATCAACTTTGACTTCCTTCTTCTTCGAATTCTTTATACAACTACTCATCTTCTAGTTGCCCTTCTAGTTGCCTCACACAAGCAAAATTTCTTTTGAAATGAATAAACTCTCGAATTGACTAGTCAAAATTTCATCAATTGCTCCTAGAGAGAAGTCAGTCGACGTGTTAGACTTATTTGGCAGATATAAAGAGAGAGGCACCGAAAATGAATTGGGTTTAACACAACAACGCGTAGATGAGTTGTGTGTGTCAACGATGCTGAAGATGATGAAAAGAGCAGAGGAGCATGAGTGATTTCTGGCGGTCGCGGCGGATGAGCATGAAGAAGGCTTACGAGCTGTATGGCGATGCGGCTAAAAATTATACGATGATTACTGTAGATTTGGAGCTTTACACCGTTTAATACGTACATACAGACTTGTTTTAGAATATTTTGTATTTGAAGCTAATAATACAAATCGCCCGTGTGCCGATTTGTCGGAAATTATTCCGGCAACTTGAGGGCCGGTTTGCCGATTTGCCGTTAATTTTCAATTCCGGCAACTTACCCGGTTGCCGCTTTGTCGGTTTACAATTTTGGTCGCTCTCAAACTGCCGGTTTGCCGATTTGCCGGAAATTTTCTTCCGGCATTGTGCCGGTTTTCCGATTTGCCGGAAATTTTCAATTCCGGCAATTTTCCGGTTTGCCGGTTTTCCGTTTGCCGGATAATAAAGTTTAGAGGGATTTTTTTAGAAGGAAACTCTCTGTGACTTTTTGAAACTGTTGCCCGTTTTCTTTTGCGATTTTTTTTCATAGATTTTGCAAGAATGCGTGCAGCTTTGCCAGTTTAGACGTAATTGAATTTCTGAAATTTCAAAAAAAAAAGTGAGCAAAATCATAAATTTTTGACATTCATTTTTTCCGGTAATTTGGCGATTTGCCGGAAAAAATTCATTTACCGCCAACTCCGAATGGTACGTCTAACCGCAAAAATTTAGGCTTTTGCTCTGGAGCCTTTTCTCTGGCGTTCTTTCAAGCTATCGTAATGTGACCACACACCTTTCTATAAATTTCAGTATTTACGCCAACCGAGAAGATCACACTAGTTTAAGGTTATAGTGCAGCTGCTCAATGGATCAGGTCTCTTACCGGGAAAATATTAACAGGCCGAAGTGACTGTGAAGCTTCGTGAAAATTTTCTGCCGTAAATTGTCAATTTTCTGCCGCACTTGGTCAATTATCTCATAAAGGTCACTTAAGTTAGCCAAACCGTGAGACAAAACTGCCCCTTATTCCTCATGCCGTCGGAAATCTAGAGCAACCCTGTATTCGAGGTCCCAATCTTTCTTCCCCCGTCTATCTAACTTTTCCTAACTACATATAACGGAGGACCATAATAATCCTAAATTTGTCCTTAGTTTTCTCCCTCCTCACCGTCTTCTAGTTTCATCCATGTCTCGCCTCATTTCACCCGATTGACGATCATCTCGGCTCCACACTTTGACACCATAGCGCGAATGAAAAAAAAGAGTCAGGCAAAAGGGGAAAAAATGCCGTTTTATTAGGAGTCAAATAGACACCAATACACACACACTCAATTTTAATGGATTAAGACGGGGCACGATTTGACACCATCGACACCAATTTGGATGGGGGCAAATAGATACATACACAAAAGGAGTTGTACCACTAGTTTTGGATCTAGAAACATCATTCTAACATCTTTTCATTTATGATTTGATTTATGCAAATGTCCTTGATTCGTGACTTCTTGTATAGTAGTTTGGATATTGTAGTATAATCATGGTAGTTGCTGAAGACTAAGCTCTTTAGCAGATTTAAGGTATGACCGTAGACAGTTCGGGATCCCGGCTTGTTATTGTGTCAGGTCCGGCCCAGGTTGTCTAATAAATACAGGTCTGCTCCAGGACGATAGCATCACTAGAATAACGGTCGTTCCGTGACTTTGTAGTTTGAGCTTTGGTCTTTGGTCTTTGAACTCTGTAGTTTTTGGTCTCATCACACAAGAGAGGTCACATAGGCCCGGCCCTTTGTGACGTCACAAATTGGCGGGAAAGTCAAATTTTGAGAAAATCGATTTTGGCGGGAATTATATAATTTAGATTTTTTGAAAACATTTTGGCGGGAATTCAAAATTTATCAAAAACATTTTGGCGGTAATTCAAAATTTAATTAGACACTGTTCTCGGTTCGGCCCAGATATAATCATCCAACAAGTCTTTCTCAAGACCACTCTTCAACACATCAGTTCTACTGTTACCAGCAAGACTGCCGCTCCACACCCTGTATAAGGGCCCTAAGGCTCGACTGAGTTTGATGTAAATCTTGCCAAGCCTGTATCATACCTACCTAGGCCCATCACAGGCGCATCTCTCACAGATCTTCCACAGGTGTTTCTAAGTTGCAACAGATCTGCACCAGGTCTGTTTTTAGCCAGGTTTTGCCTGGGTGCAGCCCAGTAGTCTACCTCTAAACTATCAAGCAGATCCTGACACCAGTTCCTAGGTCTCACATTCATCTAGGCGGATAGTCTACCTAGCTAACGCTTCAACCTCCACTGTTTTAAAGTCTTACCCTTTCTCAAACTTCAACTCATTAGTACATACATATGTTATTAGTAAATTCGCGACTCACTAATAACAATAATTCAAAGCCTCTTTCCTGGCAATGCTTCCGGTACTGAACACGGAGAGAGCGCGAGGTGGCAGGTATCCGGTAATTTGTTAACTCGAGCGCCGCGCACCCTGGCTTTAACCCAGAGCAAACAGCCCCGATGATCGCTCATGCACGAGTCTCTTACTCACGAGGTGGTGGTGAGAGGTAGGTTGGAGAAAGCGGTTCTAGCTTCACAAATTTCAATTTCAATTTACTCTCGCTCCGTTTGACTCGGGTCCCCCCCCCGCCCTCAATTTTTCGCCCCAAATTGCTCCTTTAATGGAAAGTGTTTGAGTGTGTGAAAAAGAGAGAGAGAGAGACACCTTCGGGTCACGCCAATTGCACTAATATGTGCTCTCCCATTCGCATCCTAGAGCTAAGAGGTTGAATAATTTTCGAACTAATTCGAGGAATGTCAGGTTTTTAGTTGGTCCTAACTCTTTGGCCTAGAAATTTAGAGTTCTAGTGGGGTCGTCCATCTAGATGCGGTGGTCCGAGAATCCTAGGCTTTAGTTGCCCAGGCCATCAGGCCTAGATTCTGAAATGTTGTGATGCTATTTTCCAACTTTGACCCAAAAGCCCTCTAATTTGTAGGCCATGAATCTAGGAACCTATAGGTAAGGCCTGATCCTTTGCTTACTTGCCAATAACTAGAAATCAATGCCCTAGAAGCTCGCAAAACTTTCCTAATAATTTCTAGGCCACCAATTTTTTAAAGATAGCAAGTCATCAACCAAAAATTCACGGCTCAGAAATGAAATTCGCTTTTAAGCGCACCTCTGACTTCATAGCAGTGGCCTAGAACGCCAACCGTCAGTATGTAAAAATGAGCTTTTTGGGCCTCGAACAGAACCGAACGGGACATGGAAGCCTAACATTTTTAGGCCACTGACTTTAAAGCAATTGCCTAGCACCCCGTTTTTCTGTTAGACAGCCTAGACTATCATCTAGAAATCATTGGCCTAGAATCCTAAAAATAATTCGGCCACCAGAATTTGAATGGCCTAGAAATCTAGTTGAATTCTAGGCCACCATTGACAAAGGATTGGCCTAGACTCCCTAAGAATGTGATTTTTAAGCTACTAACTATACCCTAGACCATTGTTTAAAATTGAATGGCCTAGAAACTAGAATTTTTGATTTTTAGGCCACTACCTGTTGTGAGCGGCCTAGACTATTATCTAGACCCCAATGGCCTAGTTTCCCCGTCCGCTGAAAATGTGTTTTTTCGGCCTGAAATAGGCCTAACATATTACAGTCCACCAACTCTTTTAAGATGACCAGTACTATAAGTTTAATCCTAGCTTGCCACTATAAATAATTGGCCTAGAAGCTCCTAGGCCACCATCTAATAATCGATGGCCTAGAAACCTCCCATTTTTTGTATCATAGGTGTCACCAACAACCACTGATGCCCAAGACCCGGGCTTCTCATTTCATAATGAGCAGCAATGCAAATGAGCTACCGTACCACTTCTACACACTGCCACCCTCCTTGATCCACACCCATTTCCCCTGATTTCTCGTCAATTTAAGCGGCGGCGGTTCACCACGGGATAAATTTGTGAGAGGTGAGCTGCTCACAATAATTGTTGTGAATAGGCGGCAGTGGTAGTGGTGTTAATTGTGAGTTCCCAAAGTTCACACAAAAATTTTTCGCCGCAATTGTTATCCAACCAACATAATAATAATAATAATAATAAATGAGTGTGCATAAATGTGCCCTTTTTCGCTCCACACCCGTCCTGATGGGGACGACGCTTCGTTGAATAGTTGGAATAATAATAATAAATTTGGTTGGAAAAATTTGGGCGCCCCCCTCCTAACACCCTCACACACACGAAATTTCATTTCGCGCGCGCTTCGAAAACATATTGATGACATGTTCTTCGCGAGACAAGTTATGAAAATTTGTGGCAATCGATGTGGTCCCCGCCGGCTTCAAATTTAGAGCAGAAAATTTGTGCTCTAAAGGTGCCTTTTAAATCAAGAAGGGTTACACATAAGAAAGTTTGTCGGAATCCATATTTTTGTAAGGTCCTTGGACCTGAACCCCCGGTCTTCAAATTGTTAGGCATTCTAGGTCTTCCATGGGAGACAGGCGTTTAGGCGTGGGCCTCGGCCTCTCGCCTCATTTCTACACTATGGCGAGAAGACAAAGGGCGGGTGCTCGACACTTTGTGCCAGATCATTTCGGCGTGATCTACCTTGATCTACAAAAATGCGGGAGAAGAGAAGCAGAGTTCTCAACTGATTTTACATGGTAACAGCGTGCTGACGTCAAATTTTTTTTGGACGAAAAACTTCCGCATTTTTAGTAGATCAAAAACCGTAATAGGACAGCAGGGCGTTCCACTAGAATAATTCCACTTGTTCATAATAAACGTATATTTGTCAAAATCTTGAGAATTTCCATAACTTCAACGAAAAGCACTGATAAAAGTGGTTCTTTCGCCGCGGCCGACACTTATCGGGTTCCGCGCCTATAAAGGAGACGCGGCGCGCGGCGCGAGGCAGGCGTTTTGGCGCCTGCCCGGATGCCCTACACCAAACAGCAAACATTTCTAGCTCCGTTTTTCGGACTCTACGCCTTAGTCTTTTTGTCACAACTTCGCTACACTGTGTTATTCTTCCTTCTACGACTTTAAAGGCGTGCGGAATGCGACTCACGTGATGTCAGGGAGTCTCATTGCGGTTTGATCTCAAAAAATGCGGGAAACTTTCCACCAGGAAATTGTGACGTCAGCACACTCTTGCGAGATCAGCGTTGAAAAGTCTGCGTCTCTTCCCCCGCATTTTTCGAATATCAAACCAAAATGGGACATTCTGACACCACGTACTGGTGACTTTGGATCAATGTAGATCGTTTTATAGGCCATCCATTGTTTTTAGCTCGTGGCCATTTTAAATGAATTTCCAAAATTTCCAAACACCTATTTTTTTGTCAATTCACAAGTCCCCCACGGACCCCCTCCATTGTTCCCCCGTTCACAACCTCCCTCGGTAACCACCCATTTAGCGGGAAAAAATTAGCGAATCAGTGACTCATAATCAAGTAAACCGGTCAATGCTCTACGAGCAAGAGGGGGGGAAAGGGGGTGGCTAATCGAATTATACGGGGGAATGGGATCCCTCCGCGGACACCTCGCTGCCAATTAACAAGTCAACTACTTGGGGGGGGGGGGCGGCCTCCTCACAACAATTGTATTATATTTCTTGTTATTATGATTATTAATTATTATTCTTATTAGAAATTAGTTTATGAGTATATAATATCAACTATAAAGATGACAGTTAATAATAATTGAAGTCTTCCAATAGGTGGCCATTAGAGAGAGGGGTCTGTAGTAATAGAAGAGACAAGGCGGGGGAGAGGGGCCAAATAATTAATCTGGGCCCCGTGGGCTCGTAAAATTCCGATAAAGTTGCTTGTTTGTAATTAGCTAATTCACTGAATCTTTTTTTTTTGTTGGGGTCTTACTATGTGTTTGAAACTTCCTGTTATAACATGTTTCAAAATAGACTATCTTACCTCAATGGGGACTTACAGAACCCTGGTGTTGAGATTGCTAGTCTAAAGGGTTAACCAACCATGGACCAAAAATTGCAATTTTTGATTTTTCTTACTTGAGGTTCTATTTTTTTGAATACAACGATCAGTAAGGATCTATTTCGATTTAGCAAAAAAACCTAATCAAATTTTGTAAAAATTTTCTAAAAAGTTATGAACATTCCACGTTCACACATTTCTTGCTTCCCTCATAACTTGAAAGTAAATGGAAGAGTTTTCGGCGAACAAGAGCCATGCGTTGCGTGTCGCGTCGCGGCTCGATTTTAGTTGTTATGCTCCGTGTGGGGTCCACGACTTCCCCCGTTGTCCGCCAGACGATTGTAAATGGAGCCCGAAAAATTCAATGAGGAATACGGGCCAGAACCCCGTGCACTTTTTTGTTTCTAAAACTGAAATAATTTTCAATTTTGAAATTTTCCTTGGTTTTACAATATACAAAAGCTTAAGTTCGCAAAAATTTTTGACACTGGTGGGGGCGTCGAACCCCTGAGGGGCATCCCTGTTAGCCACTGGGACCCGCCAAATTGCTAAAACTTCAAAACAAAAATTTTAGACCTTTTTTAAGGTTGCTTTCCTAATTACCGACGTCCGACTTTTCTAAAATTCCTATTCAAAGTCTTCGTAAAACTAAAGACTGGGGGGCTCGAAGCCCGGTCATCATATGAGTAGTCATCCCTGTCAGCTGGACCAATACACCACTTGCCCCCGATAGACGTGTTTCTGGTCTGTTTTACGGAGCGTGGCCTAAAAAAATCAGCCACCAATTCGAAAAGTCCATAGACCAATGTCAGTTAATATAGAAAGTCGTCTTTCAACCACAAATTCGAGCCAACCAACTAATATATAACCTATTTTCGCCGTGTTGTTCCTGTGTGTGTGTGTGCCCCTAGTTAGGCCTACCCCCCTTATGCGCTTTACTTGCTTTACAATTTCGATTGGCCCCCACACAGTTACGATCATTTTGTGTCGGGTTAATTCGACATATCGTTTAAACGGGTTACCTCTCTCGGGGCCCCCTATTCTCCTACTTCTTATTTGCTCAATATTTGCGCGTCGAAATTTCTTCTGCGATGCCCCAAATAATCAGATTCACCAATGTATAAAATAGTGCCACGCCTCACTTTTTCCACACCCATCATCTCAACTTTCCTCTTCTCAAATGCCTAATCAGCCAGTTATAACGAGGCTGCTCTTCGTGTGGCGCCCCGCACATTTTATTGCTCCTCTCACGCTTCATTCTCACTTTTTCTGGGGATCCTTTTTTTTGCAGACCTAAAAATTTGAGCTCAGCCATATTTTTGTAAATATAATCAAAAAAAAATAGACATTAGTCAAAAAAGTTTAAGCCTAAAAAAATTTTTTAGATAAAAAACGTTTTTAACTTTTTACAGTTTTTCAGTGAAATATTTTCAAATTTTTATAAAAAAATGTTTTAAGCTTATCTAAGCCTATGAGCCTAAGCCTAATAACCCTAAATATAGTGTGGGAGCTCACGCTCCCCCACTTAAGCCAAGCCTAAACGCCTAAGCCAAAGCCTAGGCCTAAGCCTGGCCCGAAGCTGAGACCTAAGCTTAAGCCTAAGCCATAAGACTGAGTTCAAGCCTAAGCCTAAGACTAAGCCTGAGTCTCAGCCTAATCCTAAGCCTCGTAAGCCATTTTTAAAAAAAATCTTCATTTTTTTGCAATTACTATTTTTTCTGAAAATCAAAAATATCGAATTTTTAGAGTTGCTATAAAATTTAAAATAATATTCAAAAAATAATCCGAAAAAATTAAATTTTTTTTCTCAAAACGGAGATCATACAGAATCAGCTTTAAAAAATTCAAACCAACCTATTTTTCGTTTCAAAAATGTTCAGAAAATTTGGTAAAAGTTTTGTAGAAAGTTTTCATAAACTAGCTGTTGAATAGGGTTTTAAGTAGGCGTTAAAACGCTTGCCTGCCTGACCTTCAGGCGACTTTCGCCTGACTGCTTGACTTTCAGACGTTCTCTGCTGCCTGACTTTAAGGCGACCTCCGCCTGCCACTCGCCTCAAGGGTATCCGAACCTTTTCTCTTAAAATGTTTGATAGTTCTTCATCAAATTGCTAAAAATACGGAAATTCCAAAATTTTGTAAGTACATGAATGCAGGCATCTGCTGTGGCCACCCATAGGCCTCCGACTTTCGTTCTACAATTGTCGTTGCCGTTTCCTTCATTTTCATACCCCAAAGTTATGATTTTTCTTACACCCCTTGCGCTGCTGCTGCTTCCGCTCGTGATGTTATGAACCAGTAGTCAGAACCGCAGGTCGAGAATCCCCACAATGATCACCCAATAAACGGGAAACATTAGCAAAAACGTATGCCCCCGTTTTTTTTTTCTGAGAAGTGTCGGCATCCCCCTAACATATGCGGGGAACATAGTTCGCTAAGTTTTGTGTGTTCCTCCAGCTCCTCCATATGGTTACCGTAGTCCACTGGTGTGTAATTGTTGTTGTAACTATCCCCCGAATACCTCTCCTCACATTCATTCACAACACAGGTGTCAACTCAACTCTCAGTGCTCATTTGAAGTTTATGAAGGTTAGCTTCCGGGGATGGCTCTCCTGGGCTCCCCCACGAAAATCAGTTAATTAAGCAATGTGGTGGTGGAGGGGCGAGCTGCTCGCTTACCCCCCCGCCCCGATTCTCTCTCTTTCATTTGTGACTTATTAGATTTTAAATCACGTCTCAAACTTTCCACTTTAACTTTCGCGTTTTTTAAATTTTTTTTTCACTTTTTCCTCACAAATTCATCCAAATAAGTTTCCAGAGTTGTCCCGCCCCATACATTTGCTAAATGGTAGAATGGGATGTGACACCTTTGACAATGTATTTGACAACAACAAACCGCCGACAAGTTCAGAGTGTACGGCGAGTATGAGTTTGGCCGGGGGAAGGCCGATAAGTTGGCCAAGACTTCTTTTTTTTTAATTTTCAAAGGTCGTTACCTTCGCGACGTTGTGCCAGGTTGTCCCATTGCTTTTTGATCTACAGAAAATGCGGGATATTTTCCCTAAAAAATGACATAAGCAAGTTTTTAAATCTTTTCTCCCGCATTTTTTTGATCTTCGTGTACCAGATCATACTCTGACACCACGTGTACCTTGAACCTCCTGGCTCCGTTTCTGAAGAGTCGTCGCTAGTGCGCATTTCTGCATTCTCAGTGGTATTTAATTTGTACAGTACCGCCAGAATCATGTAACGCGCCGCTTGTAGTCTAGTCGTTACTTCAGCTCTAAACGATAGGTCCGGGGTTCGATTCCTTGCAAGTATCCATGGAATTCCTTTCTCAAGATGGAGGTACATATGTGCTTAAAATGTGCACTAGAGATCGCGAAACTTAAACCATGGTCCGACATGTACAGGGTTCCGCGCGCACGCCGACTCGGGCCTCCAAAAAACGCCTGCGGTTCCAGCGGCGACCTCCGCCTAACTCGCGGCGCTATGCCTTCTGTATACGGCCTTCTGTCTTCCCTCATAAATTGAAATGGAAGAGTTTTTGCCGAACTAGGCCATCTTGGGCTCGGTATCTGGTCTCGATTTTAGTTGTAAAAACTAAATTATTTGTCCGTGTGGAGTGCACGACTTGCCCACGCGTTGACCGGCGGGCGATTGCCAATGGAGCGCGAAAAATTCCATAAGGAAGAACCCGTGTATAGTGCCGCGCGGCCCGAAAAGTGTCAGCCGCGGCGGAAACATTCCATAGGAAAACTAAAGTTCTCACTTTCAGAAACATACCAATGATACCAGATTCTGCGGAGATAATGCGACTTGTTGCGGATCCTTCGACGTCTCAGATGTTTGGTAGGTCATAGATCAAATTTTTTCCGCAATTTCCCGAAGATTTTCAACGAAAACACAAAATGTCGGACGAGATCTCCCCGCGTCAGGCTTCGACGAGGCGAGCCTCTCCTCCTCGTTTCCGTGCGATCCGACGCTCGGCGCGTTCGCCGACATTTCCCAATTCTGAAACATCACTCCGAAATTCGTCGAACACGCTGAAATGTCCAAAGTGTGGCCCGACAAGTACCAGGATACCCTCGAAAATGATTTGAAGGAGAAGCACAACGATGTGGATGTCAAGTGCATGTTTTGTGCCGAGAACCGTCCCCACCCGAAGCTTGCTCGCGGTGCGCGTACTCGTGCGGTTATAAGTCACCATAATCCTTCGATGCGAGTTGTGTCGGTACAGTACGACGAGAAAGGGCGAGTATTCATATGCAAATAAGCATCTTCATGGACACCAGTTCAAGAGCTCCCGAATTTGTAGTAGTAGGTGGGGCGGCGAAGGGTACTGTAGTTTTCGTGGTCGGCCCCAAGAATTTGTTTCACAAGAATTTAACTGTAGAACTCGAACTTTTCGATTCTAAGGTCTACGCAAAAACACATACGCCAACTTTTTTGAACCCTAAAAAATGATACTCATTAGAGTTCTCAGTGAGCAAAATTCGATTTTACAGTTTTTAATTTGACGGTACTGTGGGTCTTACACTCAAAGGGTTCTATAGTTCTCGTGGTGGGACCTTGTCAAATGGACGTGATTATATTTGGTTTAAAGCCCCTAGAATTCTGATTTTTTTAATACATTGGTTTTATTCTGAAAAGACTGAGAAAATTGAGTTTAGTCGAAATCAATAAAAATCGCGTCGAGACCCAAATTTCCCGGGTCTCGGCACGAAAATGGGGGAGAGGGTACTGTAGTTTTCTAGTCTTCTCTCAAATATCGAAATGGTAAAGTTTTTGCCGAACTAGGGGCCATATCTGGGATAGATTTACGGAGTGCCGCGTTGCACTGTGTAATGCGCTTGGGCTCAATTTTTGTTTTAAAACATGAGGAAGACCACAATCTGTTTTCGTGGTGGGACCCAAATGGGTCATGATTATACTTATTTGAAAGGCCTTAAGAATTCATTTAAGATTTTTATTATTTTAATTTAAAAATATCCTTAATTTTCCAATTCGCTAGGAGACAACTTCGCGTGTGGTGCTCCAGTTAGCCTAAGTAGTCCAAACGAAGAGCCCGACGGATTCCTGGTCTGCTATCTGCGGTATCTTCACCTCTATCGCCGAAATGATGGCACGTGGAACAAGACCGTCCCAAGACGTTCCACGGAGACGTTACCGTCCTAAACGGGCCGGAAGTGCCACTTGTGCCCGTAAAATACCACATTGAAAGCCAATTTTCAACTACACACAAGGACGGGGGATAAGCTTCTGCAAGAAGGTTCAAATTGTGAGTTTTGTATTCCCCCCTCATCATCTTCTTATTTTTAGGCTTGTGTCGCCCTTTTCCCATTTTTGTGAGTGTCTGTGTGTGTATGCGCACCGATTTGTATACACATAAATTCATGATTTAATAGCGTAGTAATATTTGCTTTGCCACTAACAGTTTTCGTTATTTTAAAGCCTTTTTTCTACTATTTTTGAAAAAAAAATTTAAAAATTTGAACCTTAATATTTCCCTAAAAGCTCAAAACTGTAGTGATTTAAATTTTGAATTCAGTGCTGAGACCTTTTACCGTAGTATAATCATTACTAGGTTTTGGTTCTGACGAAAGTGTTCGTTTTGGCGGAGCCCAAGCAAGGCGTAATTGATTATAGGGTCTTTGCACGCAAAAAATTTAAGGTCCGGTAGGCTTGGAGTTTTTCTTGAATTATATTAGTTTCATAAATTTTCAATTTTTTTGAGTTAATTTTACTCTCCCTTCCCGCGGTCGTGTTGTCTGATCCTAAACCAAGCTCTAGGCCTAAGCCGAAGCCTAGGCCTAAGCCTGAAATAAAGTTTAAGCCAAAGCCTGAGCCTAAGCCTATGTAACCCTAAGCCTCAGCCTCACCCTAAGCCTAACCATAAGGCTAAGCCTGAGCCTAAGCCTGAGCCTAAGCTTTAGTCTAAGCGTAAGCCTAGGCCTAACCCTGACCCTAAGCTGGGTAAGCCTAAGCCTTACCGCCTAACCCTAAGCCTGAAGGGCCTAAGCCGCCTGCAAGCCTAAAGTCTTCGTGAGACGCAATTATACTCAATTGAAAATGAGCTCACTATGAGCTGACTTCAAATTTCTCAATCAAAATGTGAAATACTTTGATTTTACGGGCGGTGGCTTTACTGGACCCACCGAACTTAATAAACTCTGAAATTTTTTTTTCATTGAATCCGGTTTCTACTCTCTCCGGCTATTTGTAGGCTGTCTTTCACTTCTTTGTTCTCGTCTGGTTGTTCCCAATTTCTCGTTCAACCCTTTACTCATTCGCCCTCTCATTTTCCCAAATCCTATTAGTTATGGACCTATCGGGGGTGACGGTGACGATTCTCGCCATTAAGACCCCCCCCCTCTCAGAACTGGGCCGATTGAGATGGAACAAAACAAAACTGTCAATTTGAATAAATTTGCAATTTGACGCGGGCGACGCGGTTACCGAGAAGGATATAAACTGGGGAACTCTACTTAGCCCGTAAGGTGCTGCTACTATTTTATCACATCTCAATTTTTACGGAATCCCGTAAGGCGTTGTCTGCTGCTTCTCTGTTTTTGCATGCTTTTACAAGTTCGGCCCGTCCGATGTACTCGGCTCTTTGTTTTGCAAAACAATTTAAAATTTGAGCCAGGTGTCTGCTGCTCCGGCTAGATTTCCAATATTTAAATTTTGCGCAATCCTGTAAGATGTGGGGTGCTTGTCAGTTTTTACAAAGTTTTTTCTCTAAGGCCCGCGCAGTGTCGGCTGCCACCTCGTATGTTTCATCAAGCTTGATCGATTCGAGCCCGTTAGCTCAGGGCCTGCGTCTTTTTTTTTCTCAAAATTCCAGCCCGTATCTTTTCGGTTGCTAAATAAAGACAGAAATTATTACGAAATTTTAACGCTTGAAGTGTCGGCTGCAAATTACACTCATTAGATTCCCTGTCTCTCCCTCTCCCTCTCTCTTCATTGGGGAGTGCTTCTCCCGAGAGAAAATGACTAAAACTGTCAATTCGAATATGCACACAGCGGGAGATGTTTTTCTGTAACTCCAGACTCCACCGTCTTCTTCGAGTGTTCTACTGCCTATTAAGCGATGATTAACTAGTCGTTCCCTCCCCCTCTCCACATACCAATAAACCTGCCAAAAGTTATGTCGAGTATGCTTTGCTCGCCATCGTGCCGGAGGCTATTTTTTCTAGACTATGATGTTTTTTGGAAAAACATTTTTCTATGGAACGATGCAAGCTAGTGCCGTGTTGCCGAGTCTTCAATTTAGGCGTATCAATTATGAGATTTCAATTTTAGTCCCTTGTATATATTATTTTTTTTGAACATTAAAATTTGATAAACTGTAGATACCCCCTAACTATTTATTTTTGTGCCAAATTATACTATACAAATTGACTTGACTCTAGATGCACCCTGACTTTTTAACCGCACTTTCGAAGATCTCATATTGTCGCCTAAAATTATTCTCAAATATTTAAATTTAAACTTTAATCCTTTATTTTTTTTCATTCCTCGGAAAAAACCCCGTTAACAGAATTCCCAATCTGGCCTCCAGTTGGCGCTTTTGTCGATGCACCATGTTCAATATTTTTTCAAAATTTGGCTCATTGACCTGAAATTTTGTCATTTTTTTATGTTGCAGGGTTTATTTTGCGATTTTTGCGATGACAACCACATTATGTGGATTAAAAAAGTTTGGAATCTCGTTTTCCCGTTTGGCTTCCATATTGCTATGTAGTTGATGCACCATGTCCAGCTTTCTGTTGAAATTTTACTTTTTACATTTTTTGCTCGCTTTTTTAAAATTTAGTTTGACCTTAAAATTTTGTCAGTTTGACAGTAAAAATTTGTCAGTTTGACCTTAAAATTTTGTCAGACATATAATTTTTTTGTGTTTTTTGTTTAAAAAATTGAAGGTTTTTCGCGATATTTAACATATTGCATGGAATCTTTTGATCGTCTCTAATTCGTGTAGCAAGTCGATGCACCATGTCCAATTTTTTAAAAGCCATTTTTACTTTTTTTAAATTGTTTGCCCAGTGGCTCTTGACCTTAAAATTTTGTCCATTTTCCCTTAAAATCTTGTGTTTTACCTTAAAATTTTGTAAGTTTGTTAAAATGTTTGTTTTACCACAATTAAAATTTCCGAATAAACTTTTCTGTTTTTTGGGTTTAAAAATTGATTTTTTTTGCGTAACACATCAAATGGCAAAAAATCATGCACCATACCGGGTGTAACTTTATCCGAAAACAGTTTTCCCTAAAAGTTTGTCAGAATTATACATTCTAAGTTCAAAACCGTACGGAAAAATTAGAACCCATGTCGACGCACCATAAGCTTTGGCCCACTGAGCTTCGTTGCTGGTCCTGCATATCTCTTACCCCCTCTCGCCGCTCTCATAACATTGACCAATTAATTGGGCGGAGCGCCGTTTGGAAATCGATTGGCTGACGGGCCCGCCCCGCCCCCCGTCCCGCAAATTTTCGAAGGAGCTTTGGACTGGACAGACACACACACAAATTCACAAATACACGCCAATTTGTCGATTTTTCTTGAAAATTTCTTCATTATTGTATATTTTTTTGTGTCGTCCTCTTGTCATCCGCCATCCTCGGCGTCTTCTTTCGTTTGATTATTTCATACACCTACCACGTAATTCGCCTATTATCCGCCTCGTTACCTTCATCTTTCGGTCGACGTTGACGTGACATCGGCGCTCCCGAAATGAGAGGAAATAGGGGGGGGGGGGGGGGCGGACGACGGGCCCACTACGACAGATCACGATCATTTTCGTTCTATCATCTTATCCGGCAAACCGTCGTCCCCCTCCATTTTTCAACTTATGTAACCAAAACTTTTCTTATCTTGGGATTTGGTCCCCTTTTATAGCAAATGCACTGAATTGACAACATATTAGTTTCTCACTTTTTCGAAGTTTCACAATTTTTAGTTAGTCCGTTTTTTCAGTCTGGCCGAGTTTTCAATTTTCCCCGGCCAGGGAATCTAGTAGTATTCACATAATTTTTCTTATTTTTGGTTTTCTAGGCGACCACTCCCTATTCTAAGCCCGGCAAACTTCTAGGTCCCCCATTTACACCTGACTTCCTACCTATCTGAAATGCCTACTTGCCTTCCACCTGACAAAGATGCCTACCTACCTAAAACCTTCCTACCGAACTATTGACTCTTACCTACATAAGACTTGCCGATCTGAAATACATGCCTACTAAGACATGATACCTAGCCTACCTATCTAAGCTACCTACTTACAGATAATGTACCGACACAAGACTTGCCTACCCACGCACGGCATCATTTTTACCTACCTACCTGTACTTAAGATCTAAGACCTAGATCTTAGTACATAAGAATTTTCATCTTAGATACCTACTCAAGGTCCTGCCAAAGATGCATGCTTACCTATGACCTACTTACTTAAGATACCTGCTGGCCCAAACCCTACTACCTACATGCGCTAGCTCCCCCACCTACCTAAGATACTTACTTACCTATACCCGATTTACCTACACAAGACTTGCCTACCTAGGGCCGCAAGGCTTGATTTTCTTATTGTTAACCTACCTACCTAACTATAAGTACGATTTAAGACCTAGACGTTATTGCAAGACAGAGTTTCTGTCTTAAATACGTACTCAAGATCCCCCACGATACCTAGAAGCACTTCCGACCTAAGATGCCTCCTAAGCCCTGTCTCCCTAAGACCTAAGTGTCCTATAAGAACTTCCTAACTAAAAACACCTACCTAAAATAAGCCTTACGCCAAGCTCAAAAATTTAGAGCATCTGCATGAGATAAGGCTGAAAAATATCAACGAATAATGGAGAGCGATTATGTTCCTGCCCTCTTACTAGAAAGTTCGGAAGTAGTCGCCGCAAAACGCCATTACTATTGCTCATCGAGCCATTTCCGGTACTCAGTACTTTCTCATCCCCCACTACTTTTTTCGCACTCTCTTCTCGATTTGATTTGCATTCTTTTTGCCCTCGTTTCGAGCTGAGCCCGGTTGATTTCCCGCACTTTCTCAATTCTTTCCTCTTAAGCCACCGCACTTGAACAGGAGCAGTTCACACATGCAAACTTGGACTTAATCATATTAAGACCCCCCCCCCCCACCCCTCTTAATTTCCTAATCCCCTCCCCCTCCTCCTCATCATGACCAAAAGACAATTGTCTTCAGGCGAACCATCTTCGTGAGAGAACCCTCACACGGCAATCTACCGTCTGTCGAGCACAACGTGCGTTCAAGTGTTGTGTCGACAGTGTCACGAGCTGATGGGCTTCCCGTGGCGAATCGCCAAATCCGCGAGCATCGACACTTTCCTGCTTGCCGCCAAGCCAACGCTTGTGGCGATGTTGTGTAGGCTTGCTGGATTTCGATTCGGTTCTTCTTGCAGCTGGTGAGTTAGTTATTTTTAGGAAGAAATTATATCTGTGTAAGTCCCCCAAATATAAGCCATGTCCCTCTTAATAATGAAGCTTCTGACTTAATTTACTATAGATTTTGAATTTCGTCTATCGAAAAATTAGGTTCACCATGATTTGTCGATTTTCGATGCACTATGATTTGTTGCTAGGATAGAAAACAAGAAAATTCGTGGCCTACGAAAGTTTTTTAATTATTTCTTTTTGTCGGCCAAGATGAAAAAGTCACCTTTTGTGTATGGATGCAGCATGACCCTTTTCAGTGGATTTTGGCCCAAAAATCGTCAAAAGTTTAAAAATCAAACTCTAAATTACCTTTTTTTTTCAAATTTTCTTAACAAATTGGAGCATTTTACAGAAAGCCGATGCACCGTGATTTTAGTTAGAATTGAAAAAACATTCTCGGGCAAGTTGCAAAACTCACATTTAATGTATATTCGATGCACCATGACCATTTTCGAAATTTTGCGGTACCTATTCAAATAGTGCACATAGGCGTACAAACATTGGTGGTGGCCTCGTTTCCTCATGCTTTCGGCCACGAAAAAAAAATATACAGTTTTTGGGATCGGGGAGATGCACCATGATTGTTTTTCAGTGAAAGCCTGTTTTTGCTTAGCAGTCTCAAAGGTATCCGGCTTAATGTTCCCACGCTAAAACGTAATCCAAACATTTAAATTTTAGCGTCAAACTTTTAGGCCCGGCGTACACTAAAAATTGTAAACTTTCAATATATCAAAAATATTCTGACCTATAGCAAAAATTAAACCTAAAAGCAATCAGATATTTTTTCAAAAAAGCTTCTGTGTGATGTCCAATACATGGGTGTGCAGCTAATCTTAAAGTGCTGGCCGTGCTTAACATACTCCGAAAAAGAGTGATATTATTTTATGCTTTTTGGAGCACCAAAACTACTGAAGTTCGTGCTTAGCAAACAAATTCGGCATATTTGCCCCCCTGGTCCACTAGTTAAGCAAAACCCACCGCTGAAAACTAATCAATTGGTGTTTGAAACGGGGAGTGCTAGTACTAGAAGTATTTGGCTGTTCAAAATCTCTTTATTAAACACTTCTTTGTGTCTATTCTGCCCTTTCCTCCTCCCCGCTCAAAATCACTGTACCTCTAATTACGGTCAACTGCGGGTTGAGTTTAGTGAATGAATTGTGAAATGAATGAATGAATGAATGGATAGGTAGATGTGGGTTCTATGTATGTGGAGAAGTGCGACACATGAGCACAACCAGCCGTCACCGCCACTACCACCAGCAGTAGCAATACCCATCAAATATAAGCCTTGCATTTCATTATTTCATAGTGTCATAGATAGTAGCAGGCCCCGAGGTCCGAAAGGCCTAGACCAGGCAGCCGGCAGGTTATATTCAGTTCATTTTTTGACACCCCCCCCCCCCCCCCCCCCACCTCTACAATTCTTCTTCTCTACACATACATTAATCGCATAGTCAGGCCATTCATGTTTTTCACACAATTTTGTTAATAAAGCCGCTCTGGTGGCCGCCACCTCTCAGTAGTCCTTTTCCATCGTCTCTTTTTCCCTCTCCCTTACGAATAAACAAAAACAGTCATTGATGAACGACGTATCGGAATTGTAGTCTCGCAATTATGGTAGGACATATGTCTTGCCACGAGCCGTCCACTTGGCCCAACGAATCACTTGGTGAGTCTCTTTACAGCTTGAAATTTGTGTTGTTTTGTTGGGAAATATAGTTAATCGTTTTTTTAATTAGTATCTCCAATTAGGCCAAAACTACAATCGTGAAAGAATAGTTTCTGCACATGGTGCATCGCCCTGATCTATCTCACTAAACTTTTTTTGGGCTTCATCAAAAACTTGTTAGCTAATATAGTTTAGCATCACTCTATTGATATGTTCAATTTGAACCGAATATGGTGGATCATTTATTGCAACTGAAACAATTTGGCGCATAAAATTGCAACTATGTAGTTTATGTACATCGATCTTGATTACCGTATTTCCTCTATTGTATTGCACCCGACATAACTTTGAAACGTTATATCTCGGTTCATATTGAAGATATCAATAAATACTATTCCGAAATGAAAGCAAAAGAACTAACAAAGATTTTGTTAGTTGACCATTTTTGAATAGGACAAACGATTAAGATGTAACAAAAGTGGACAATGGGGAGCAATACTAATTGTGTAAATACCTTATATCTCGGTTCGCTTTGGTTTTAACAAAAATTTTAAACTGACAAAATATCATCTTAATGACCATATTGTAGTTAACAATATTTTGATATCTTTAAGAACTAGCGATTTTCGACATGGTGCAACCTCAGTCACCTAGTCTAACTTTGCTGGATTTCTTAGTTTTAGTATTAACCGTTCATTTTAATATACTTTTATAAATAGTGTCCTAACAATTTTTTGATACCTTCAAACGTGTTGAACAGGAGCGGGGATTATAGCATGGAGCTTTGATCCTATCTTGCCTTAATTTTCAAGCTTATTGTTGTAAAAAAAATTTAGACATGGTTCATTGACCTGAACTACCTGATATATCGTACTTATCTTCAATTTTAGCAAGTTTTGGAACCAAAAAAATATTAATAAAATCGATTTATAACATTTTTTCCATTTTCAACCTTCCGACAAAAATTTTCAATTTTGACCTTTTTTTATATGGGAACCCGGCAAAAATCTAAAAACTCCCAAGAACATTCTCCCACGAAAACCTAAATACTTGTAAATCTAGATCAGTCAACATGATTTGCACCTTCTTCCCATGGGATGGCTAAAGAACCCAGTGCGATGATGAATCGGCCTGTGGGCCGCGAGCAGACGCCGCTCTAATCACTTTTGGAGCATTTGTATATATATAGCGAAGAATTTACGTTGGGACCAATGAAACCAATAGAAATCCAAACATATTTTTGTTTTGTAATCTCTTCCCTCGCTGCTATCAGCTCTCTTGCCCCTCCTTAACCAATCAGAGACGCAGGCACACACCGCACCGCCAGTCCGTCATCGTCATCGAGTTCCGCAATTAGTCGTCTATTCTATCCGTTTTTGATTGGAGTTATGGAGCGGAAAGAGAAAGACCGAGAGAGAGAGAGAGAGATTAGCTCTTAGATTCATTCAACTAATCTTGAAATAACACACCCACACACATACAAAATGAATAAGGTATCTTGATTTCTAGAAAATCATGGAAATCAGCAAATTCGCTAGAAATGGAAGGGGAAGCTTGAAATAAGAGCACTACTTGATACCGAGTTGGGTAGTGTTTTAATATTTGAAGAAATATTACAATTTTGCATTCTTTATACTTCTAAAAACAAGTTGCTTGATGCATCATGCCTCTTTAGATAACGTTGTCGTTGTTTTAGGCTTAGGCTTAGGTTTAGGCTTAGACTTAAGCTAGGCATAGGCATAGAGGCTTAGGCTTAGCATAGGCTTAGACTTAGGCTTAAGCTTATTCTTGGGCTTAGGCTTTAGCTTAGGCTTAAGCTTAGGCTTCGGCTTGGGCTTAGGCTTTAGGCTTAGGCTTAAGTTTAGGATATAGGCTTAGGCTTAGGCTTAGACTTCTAGATTTCTCGTAAACCACCAAATTACTGTATATTCTCTATCATAGATACTACTTCGGACCAGCTTATAACTCAAGTCTTTTATCAGAGATGAATCACTGCTTTAATTACAACAGGTTAATAAATACACCATATTTTATTAGTTTAAATTTTTTGATTAAGCTAACGAGAAAAATATGACTAGTCAAAGATTATCGATGCACCATGGTACTACACTTTACTTTGCCGGCTCATAACTCGGTTTATTTTCAGGATATCAAAAAGGTTTGATACAAACCTATTAAGAGAAACATATAATAAAAATATTACTATTTTGTAAGACAATTTTGGTAAAACTAATAAGAATCGAGGTAGATATAGGCCGTTGAAGTAGCATGATGCAGTTGAAAGCCTACGTTTTTAGACTTAAAGCTTGAAAAGGATGTACCGTCACGTATTTCCTCTATTATTGTGCCACCCATTGTTCAACTGTGAAATCTTTTATCTCAGTGACTGTTTGTTCTAATCAGAAATAGTTAACAAAATATTTCTTAGTTCTTTTTCTATCATTTCTTAGTTGACCTTATATTGATACTAAAATAAACCGAGATAAAACGTTTCAAAGTTAAGTAGTCGGGTACAATAATGGACGAAATCATGCGGTATTAAATATTTTGACACGGTTAACTATTTGAGCTAGATTCTCGATATCATTTTAATTTCTGATCCATGGCTCGTTCAATTGTCTTGCCTAGAAAATCTCTAAAAATAACGTCTACGAGAGCGGGTGAAACAATAGGTGGTTAGATGTAAGTTGATGCCCCTGAAGGCATCCGGGATCCCGGTGTCCGCAAAAACAGTACAAATGTAACATGAGATGTACATCCCCCATTTGTGGTCGCTCTAGTCCAAGTTGAAATCGTAAGCATGCAAAGACATTGTTAATATAGCCGTGACGCGACGGTGGGCTCGCTCGATGAATCAAGATCGTTTTGGGAAGAGAGGGACTGAAAATATTAAAAAAAGATTTGCATACCCTCTGTAATTGTTTGAATCATCAGCATCATCATCATCATCAATCATAACATAGAGGAAACTTTTCCTGCTGTGAATGTGTCTCCTTTTTAGTACAGTCAATAAATGTGTCACTTTAAAGGGGGAGAAGCTTTTCACGGATGCTTTGCTCTCGACCTCCTTCCCTCCTCGCTTATAAATTTCCATTTTTCTCTTTAGGCTCAAACATTGATTGATTTACTTATTCTATTGACATTCTGATATTAATTTGATCATCTACTAAAAGGTATATATATATATAACGTATATCAACTCTTGGAGCCCATATCTTTAATGCTCATTAAACTCTGCTCCCAGTTAGGACTCGTCCGGGAGTGTAGTACTGGGTGTGGGATAAGAAAGTTAGGATGTGACGGGTTTCATGTTCATCTCGAGCTGCCAATCTTGCACATTAAGCGATTGGCTCATTGGCACTCTGTTTGTCCTCAGGGCCTGCCGCGGAGCCATCTCCCGTTTGATATCTGCTCCCGGACGTTCCCATGGCCGGAGAGAGGCGCCGCGAAGCACAAGCTCAACCTTTTCTAATGTAATGGGCCGGTGTACAATTAGGGGAAGAAAACAAAGAGGATGAGAGGTTGGGGTGGATGAGGCAGGGAAAAGAGCACCACCACCAACTGATTTGCTGGTTGGAGAGGAGCTCGTTCTGTTTTCTTGTCGTCGTAAAGTAGGAAGAAGAAGAGAATCGCGCTAGTTAGTGGTTAAAAGAATCGAGACCCGAATGTGATAGATGTGTCGCCAATTTAGCCAGTAGGATTTTTGCTGATTTTGCACACTTCTTGCTCTAGACATTACATCCCATCTTACGCTTCATTCATTGTGGTGATTTTAAGATTTGGGGGACCTAGTTCGAGCCTCTACAGTATTACTTTAAATTTCACTATTGTTTGGTTTGAAAAGAGACTATTGCGTCATATCATTTTAAGGCACCTATGTATACAGTTCAAAATTTTGCAACATTCCTGGACCATAGCGATCTTAAAGCGGGAAATATAATCCAGACATTATCTGATAACCCATTTTTTCGAACTCAAAAAATTGAGTAAAGCCAATTGAATCGTATCCCAAGCCTAATGGATTGCAAAGTTGGGCCATTCTGAATAGCTTCGAGTTCCAAATAATCACTGAAGCTAGCCAGAAGCTGAACGCACTGACCTTCCTGCCAAGCCTTTCTTTAGTGTGAATAAGTCTCAGACTAGAAGCACTACCTGATGAGAGAGATTCCTTTCTCTCATAAGTAGTCTATTTCATGATGCAAGAACTTACAGCATTTACATTACCATGTAACATTACTTAAGATCCCATTTCCACTTAAAATGTGGGAAAATCGATACGGTTTTATAAGAAGTGTCTTTTCGCATCTTTATAGCCTAGAGCAAAAAGCCAAATTGTTTGGCAGATCATGTCTCCGACAATATTCTGATCGATTAAGAAACTTTTCCAAATCTGCTCGGTTTTTTAGTCTACGCGCCCAGATAACTGTGTTCTCGGCATGGCCGATTTGCCGATTTGCCGGAAAGGATTTTTACGTACTTTACGACAACTTACTGGCATTTGCCGGAGATTAAGGGAGAATTTTTTTGAGACGGAAAATTTTTTCATTAGAGATGTTCATAGAATTAGCTTACACTTACAAAATAGGTCTATGAACATATTCAAAGACCGATGCGCAACTTTGCCGATTGAAATTGAAATTCTGAAATTTCCAAAAAATAAATAGGTGACACAATTTGCCGTTTTCCGGCCAATTCGGCAAATCGGCAATTTTCTGGATCTGCAAATTTGCCTGAAATTTTCAATTCCCTTTATTTGCCGGGTTGCAAATTTGCCAGAAATTTTCAATTCCGCACATTTGCTTCCGGCCAATTCGTAAAATCGGCAACTTTCCGGGTTCCAAATTTGCCGGAAATTTTTCAATTCCCTTTATTATGCCGGGTCTCTGCAAATTGGCCAGAAATTAATTCAATCGGCAATTTGTCAGTTAACGTGTAAATTTTCAATTCCGGCAATTTGTCGATTTACCGGAAAAAATCGTTTGCATCAACCCATGTGAACGCTAGCACACCTCCTAGTATTAAGGCTCCAGCTAATTTCTGACGCATATCATGGTTCCCAACTATACGTTCCTCCCCTCCCCCTTCCCACACCATTTCGAATGGGCGCCAATTATTAATGGATTCTCAATTCCCATCATATTGGGGGGGGGGGGGGGGGGGGCATTCGTACAGTCTCAATACGAATAATACTTATAAGCCCTCTTCTATGCCCAAAGCGCGGCCTTCTTCTTCACCCCTCTAGGCGATAAATTCTCATATTTAGCATTTTGTAAGACTCGGTCTCCCCCTTTCAAGTATCTCTGGGCGATGATTCCCGCTCTAGCTCTCGCACACACCCCATTTTTTTTTCACAATAATCATTCAAGGTGGACACCAAAAAAGCCATCAGTTCGATTCCGGTCAAATCGAGAGAACTGGAAGAGAGAGAGAGAGAGAGAGAGTAAGAGGAAATGAGACAGAGGGGTGAGAGATGGAAAACGAACAAGTTTGATGGGCGTCCCCCCCCCCCCCCCCCAGGGCCGCTCCTCATACTTAAATTTAACAGCTGTCACTCTCTTTTGCTCTTCAATTTCTAGCTCTCTAAACTCCTCAGGTCTACAGTAATCGGGGAGGGGGTAGTGATAAGCCTCTTCCCGCCCCCCCCCCCCCGGGGGTTAGGTGTCAGAAATTAATCATAGATGCCACGCCTCTAATGTTTTCGGAAGCAGTCATCCTCGCTTTAAATCTTTAATTCATTAACCTATTAATTCATTAGTCTTACACTGTCAATTTCATAACTAATGTTGAAAAAACTTCTCAAAAAAAAAAGTTTTGGCGGCTTAAGAAATGGCCTAATATTAGTTCGACTTTTCAAGCGGCTGGAAACTAACTTTTTTTGAGATCCACCCTAATTTCAACAACGTAAATAAAAAAATTTGGTGACCCAATTAAATTTATTTAGGCCAAATCTGGTGTTCAAATTTTTTAGGCCAAATCTGGTGACTAAATTTTTTAGGGCCCAATATGGTGACAAAATTTTTTAAGGCCAAATCTGGTAACCACAATTTTTTAAGGCCAAACGTTTTTAAATACCAAATTTAGATGTTAGAGCCAAAGTGACGGTGCAAAGGTATTTAGGGGCGAATCTAATGACCACATTTTTTGGCCAGACCTGTCCCTAATTTTTTACAGGGCCAAATCTGGAGACCAAATTTTTTAGGCCAAGTCTTGGGATCATCATTTTTTAGGCCAAATCTGATGACCAAAATTTTTAGGCCAAATCTAAGGACCAAGAAAATTTAGGATTTAGGGGCCAAATCTGGTGACCAAATGTTAGGGCCTCTGGTGACCAAAATTTTGGCAAAATCTAGTTACCAAATTTTTTAACCAAATCTGGTCACCGAATTTGGCCAAGCCTTGTGATCAAATTTTTTTAAATTTTCAAATCTGGTGACCAATGTTTTTTGAGGGCTTTGGTGGCAGCATAAAATTTTTAAGGCCAAACTTTTAGGACAAATCTGGTGACCAAATTTATAAGGCCATAATAACTTTTTTTTGAAAGTTTGAAGACGTTTCTAATTCATAAGTCTTTATCTTTTTCAATTTAATCTTCGATATTCTAGATTTCAAAACGATGGAGGATGCGGCTTACGCGTGTGCTGGCTGCGACTTCAAAGTGAGTGTTTTTTGTTGTTTCCTCATCAGCATCAGCTCTATCTTCTCCCCACCCCACACCGCTCATGGCCACTTCCTGTAACCTCCAATTGCCATTCATTTCACACAGTATTAGTACCACACAACACCCTTCCATGCAATTTGACTCATTCATAGCCCTTTTCTGGACCATGTCTTTCTTCCCCCTTCTTTCTCTCTAATACTCAACCTATACCTACCTACCCGCAATTTAATTGTTGAGCAACTAATTGATACACTCGGACGGCTCAAACGATGCGCGTCCGTCGTCGAGTGCCCAAGACTGGGACCGGTTTTCAGAATGTCCAGTGTATGTGTGTTTGTGTCTACGGCTGGCAGGCAGCCACACCACTCCGATTCGTTAATTTATTGTGAGATGATGACTGTACATTACTTTAAGTGCTGCTGGTGCTGGTGGTTTGCATCATATAATTATAGCTGATTATATTGACACACACACACATACACATTTACTTTCAATTGCTTTTACCCAATCGTTTTTCTTCCATTCCCCAATCTCCTTGCTCCCATTTGGCCCTTTGATATTAACCGCGTTGCGCGTTTCGCACTAATTTCGCGCCCGGACCGGTGTGCTCGGCGCGGCACGTCTTTCATCTTTTTACCTCAATTTCATTATGATTATAATAATCATATTATGGAAGCGAGACACGGCAAAGACGCGCTCAAGAAACTGATAAATGTGTAGAGGTCGGGTCCTTTTGAGAGAGACGGAGAGAGCGAGGTGTGATAAGAGCGCCTAATGAGCATGGGCAATCATCACATTACTATCAGCAGCATTAAAACTTTTTCAGAAGACGTGTCGGACTTCATTTGAAGAGCACACAAAAGGACACGAAGAGGAGGAACGGGAGCCTCTTCACAGAAGGCGTGTGCGCTGTGCCTGCTGAGCCCACCGACCACCTCGAAAAGCACCTTGTCGAGCACCCTGCTATCGCATCGCCGAGAGGGCTATCGAAAAGTTCCTGCTTACTGAGCGAACAGCCAAGTGAGTGTTTTTTTTTCACTCAAATATTTAGTAGTAAATCTTATACTTTTATTTCTAGCGGTTTCATTTTTGATAGCTAGTTAAAAACCATAGAATAACAATTAACTTTTTGACACCTGTCGTTTGAATTTTTTGACAAAAATTTTGTCGTTTGAATTTTTAAAATATGATCGAGACAACCGAGATATAAAAGGTCAAAGTCCAGTGAGAGGGGCCATAATGATAGGGATTATACGGTAGGTATCGAAAGAGACTTATAAGGACAAAGATAATGGCGCTAGAAAGTTTAAACTAGTCCAATTTGAACAATAAAAATATATATCACGTACTTCCCATTTAGTATAAATATTTTAATGAGAGTAATCTGAGATACAGTAAATTTTTGATTAACAATTTCTAGGCACCATGTACAAAACCTAGTCCCCAGCCCTAAAATTAAATAGCACGTACTTTTTAGTATAGAGCCTATTTCAAAAGTTAAGCCATCTGATACACAGTGAATTCTACCAAGTCCTAGTCGATGCACCATGTGCCCACTTGACTTTCACGGCGCACTTCCCGGCTAATTTCATACCTTTCAGAATCGCGATTTTCAACTATTAAACTATAGAGGGGTTTTTAATAAACATTTTCTCTGTTGACGACTTTTTTAACGTAGAATCAAAGACTACCTCGATAGCTTGATAGTTAAAGTCGAGATGCAAGGTTTTTTCGGAAAAATCACGCGGTGTTTTCGGTTTGTCTACGTACAACGAAAAATTCGGGAGAAGAGACGCAGAGGTTATCAACTCGTATGGTAAAGAACGTGCTGACGTTGTCACATATTTTTGAACAAAAAATCATTTTTAGATCAAACCGTAATGGGGCAACCTCGCACCACGTGAAAAATTAGTTTTTGAGGCTTCTCTAGTCTAGAGACTCACTAAAGTATTTTTTTTGATTGGCCTTGTTTTTTCTAGACTTAAAGACCAGTTAGATCCAATCAAGGTTTTTCAGAGTGTCGATTTTTATGAATTTAAAACTTTCAAATTGTAATCGCACGTTCCTCCATTTCAACCCCAAACACGTTACGATATTGTGCTATCATAATCATTCAACCATGCTTGCTTGTGTGCAAGTTGCACAGGGTGCGCCGGTGGTGGAATTGGCATTACTGTAAATGTCCTGCGTCTCCATCCTTGCCCCCAGTGTCCCCATCGGCATAACTATTCGAGAGGACGATCCGCTTTTGCATATCTAATTGTTCAGGATTGTTTACGCGCTCTAAAATTCAATCCGTCGCCAACCACCCGCCCCCCTGCCTGACTCTTCAATTCATCATGAGTATTAGTGTATTGATTAATTTTCGAATTCACGAATCAGTGCTGGCGCCCTGCTACTAGTAACCAGTGAGGTCATAGCGTTGCCCGCAGTTTCGATAGGGCTAATGAAATATGTAGTTTCTCTAGGGGCGGGAGGATAGGTTTGATCAGGAATTGGGCGTCGGTTTGATCTACGTAGATCTATGAAGATCGCGGGAATTTAGACGCAGACTTCTCAACTGATTTTGCATGGTTAAAAACGTGCTGACGTCATATGTTTTAGGGGAAAATATTGCCCGCACTTTTTGTAGATCAAACCGTAATGGGACAGCCTGACACCATGTGCTCAGTTATGGTCCAACTAGAGGGTTTTGTCGGAAAAATCTGCAATCAATTTTTTAAACTGACAACACATTTAGCTCCTTCTCCAAAACTGAGCCAAATGTGTAATGTCAAACTTTTCTTGAAATTTTTGTATCGAAATTAATTGATGTTGAGGTGAATTTTCAAATTTCAAAAAAGGTACTCATTTCTATCAATTTGTCTTCACCTATGTTTTCGACTAAGTGCGAGGCTAGAGGTGGAGGTCCCCTTAAAATCATAAGATAGCCTTATGTGATGTCGAAAAATGCCAAAAACCGCAATGTATTTTTCTATAGTTTCCCCGTGTGTAGAAGAATGTAAAAAGAGCATGCATTTTGTGATCATTTTTTGACATTTTCCTGCATTTTTTTTTGACAATTTTTTTTCATTTTTCCACACAGATGAATAGCGGAAAAACTTAGGAAAAAAATACCATATTTGCATTTTTCATGATCACATGATCCCCCATAAGGTTTTTTAAGGCATAATATTGATATTTATTAGTCTACTTCGGATGCATAATGCCTACTATTGAAGGCAAATCAAATCGACATCACTTTTTGCTCATTTTCAAAACTGAGAGGCACGGCTTCTATGTTGACTACTAAACCAGTCAATAACACTTATAAAATGTTTGGAAAACACTCATACACAGCCACGTCATAGCTTGGACTGGATGGGACCCCATTTCTTGAATCATAAAACCTTGATTGTTAAACTATCATCCCCCCCGCCCTCCTCATTGGACGACCCCACGGCTCTGTCTCCAATTTGTTCCCCGTCCTCTTCTTATCACCTTGACGCGTTGCTAATTGAAATTTTGCGTAGAGGATTTCACTTCCTCCCCACCGCTTCCTTTACTCCTTGGGGGATAAGTATGGAGAGTGTTTATTTGTGTGATTGAAGTGAAGAAGGTGGCTGCCTCATTATTTCATTTTCGTCGCTTTCTTTGAAAGAACAACTTGACAGTTTCCCCCCCCACCCCCCATCTTAATAATAATTACTTGCAGACAAGCGTCGTGTTCACCGTAGTCGGAGTCGAGCTAAGAATTCGCGCATCGCTGCTCGAGTTGCTCGATGGCGTTCCGAAGCGAGTCGCAGCTGCAGACGCATTCCCTTCAGCTCGTGTTCAACTCGTTCCACAAGTGCCCCACGTGTGGCGATTCGTTTGATGACAATACTATTGGTGAGTGTATTGACACACTTTTGGGTCACAGTCACGCTTGATCTACGTGTTTTTAGACACTTTTGAGTCTACACGTCGTGTCAAATGTCTCTTGGGCTAACTTGATCTGCGTTGATATACCGAAAAATGCGGGAGGTTTTGGGCAAAAAATTCCCGCATTTTTTGTAGATCAAACCGTATTGGGACAGCCTGGCATCACGTGGAGAACTCAGTTAAAGTAAGAGGGTTTTGTCACTAGATTTATTTTCTGTAAACTGACAACACATTTAGCCGCACTCATTCTCCAAATCTGAGCTAGGTTGTCGACCGACTTTTTTTGAAATTTTTTTAAACGAAAGTAGTTTTGCTAGTTTTCCTAAAAGGAGAAAGAAGGGTTGTCCAATTTTTATAAGAAGGTTTTTGTCGACTCGGAAAAACGATTTTTGTAAATGACAACCCTTTTCGCTCGTCTTTTCAAAATTAATTTTTTTCTCTTGGCACTTAATCCCATTTTATGTAAATTAACAAAAAAATGTCAAAAAATCTTCAAGTAGTTCTACAGGGTGGCCTATCTATAGGGTGGCCTACATTTTTGCACGGGTTGTCTAGATCCTTAAACAGGGATGGCCTCTCTGTAGTGGCCTAGACCTTTTCTACACGGTGTAGATTTTCACTGGTGGCCTAGATTCTCACACTAGGTGGCCTAGATTTTTCCACTAATCATAGCGTAGATTCTTTACAGGGTGTCCTAGATATTCACGGTGTCCTACATTCTACACAATTGTGGGTGACCTAGATTTGTTACACTGGTGGCCTAGATTCTCTACAGGGTGCCCTAAATTCCTTATAGGATGACCTAGATTCTTAAACAGGATGGCGCTACCTAGATGTTGACACTAGGCCTTGATATTTTACAGGGTGGCTACCTAGAATTTCTACAATGGCCTAGATTTTTTGCAGGGTGATGCTTGGATTATTAAACAAGGTGGCCTAGATTCAGGGTGGCCTAGATTTTATACAGGGTGGTCTAGATTGAACGTTTACACTGGTGGGCTAGATTCTTTACAGGTTCGCCTCAAGATTTTCTATCGGATGGCCTAGATTATTAAACACGGTGGCCTAGATTGGCCCTTTACAGGGTAGCCTAGATTCTTCACCCAAAGCGTAGACTAGATTTTTCTGGTGGCCTAGACTAAAGGGTGGTGGAACTAGATTTTTGCACTGGTGTATGGCGTGGATTCTTAAACAGGCTGGCAAATTGTTCCCCTTAGGGGATGCCACTAAATTCTTAAACAACCTAGATTTTATACGGGAAGGCCTAGAACTACTTTTTGTAAATGACGGCACTTTTTGCTCGTTTTCCAAATCGTTTTTTTTTCAGAGCCATATGTTGGAGCGTACACCAAAGAAGAATGCGAAATGTCTGAAACATTTGCCACAAAAGAGGCATTCCCCTCCCCCCTGAACTCAGCGTCACCTACTGAACACAAAGAAGCATCTGGAAAGCTGGACTCGACTTAAACTCTCAGGTGAGCCGCCGCCGCGCCTCAGGCTGCCGCCTGGCTACCGTAGTCACCGTACCTTTAATTGCTATTATAGCCACGCCGCTCAGCTACAAGCTCGGAGCGCAGAGGTGACAGAAAAAGCCGACAAAACATTAATATTATTACACTTTTTTATGATTGAATGCGAGAGAGATGTATGTGTGTGGAGTGGAGAGGCGCATGAAATGGTGTTCGGGTTCCATAGCAAGCTCATTGAGCACAATGATTTGTTTTTTAAATATATTTTATTGGAAATGACAGAAGGTGAATCTTAAAAGGAACGTCCAGTATTTAACTTAAAGTATTGATTTAGCACGTAGTTTCAGCCTGTCCCATCACGGTTTGATCGTACAAAAAATGCGGGAATTTTCTTCCCAAAAAGTTTGACGTCAGAGTTCTTAACCATGCGAAATAAATTGAGAACTCTGCGTCTCAACTCCCGCATTTTTTCTAGATCTACGCTTAGATCAAACCGATATGGGGCACGTTGCATTTGATATTTAAAGGGTCTCGACAATAAAGAACTCAAAATAGCCTTGCCAAGATAAATGGGCGGAGCTTTGGTAGGAATTTTCATAAGTCGAGGACTCCGCCCAGTTCGTTGGCCAATTTGGGTTTTTGTTCGTGCCTTCAATTTTTAGTGTTTCATTAATTTCCAATAAGTTTAAGATTGAAATAGTTTTTGAGGTGAAAACTGATCCTAGCATGGGCCGCCCATTTGTTGGTTTTTTTTTTGTTTTTTGTTCTTTTAAACTAAAATTCCACTGAACTTGTCTAATATCAGTTTCCATTAACGAAAAAATTCGAAATGCCATGAAAGGGGAGGAGCCTAAGCGAAGACTTTTTCGATGAAATTTGGCCAAGTTGCGATGTTTTTGAATTTCATATTTTTGAATCAAGTTTTGAAATAAAAAGTAATATAAAATTGGAAAATAGGCTCCGCCCATTTATTGGTTTTGTTGGGGTATTTTTTTCTGCATGGATCATTTTTGCATCCGAAAATTTGTCGGAAAGGCATTTTTCCCAATTTTTTTCCGTAAACTATCATCAACTTTTGAGATTCAAAATATCCAACATAAGCACGGGGTTCTGGCCTTCCTCATTGAATTTTTCGCGATCCATTGACAATCATTTGCCTGCCGGACAACGCGTGGGAAAGTCGTGTACTCCACGCGGACAATTAGAGCCATTTTAAGCGCCGCAAATCCCAGATATGGCCGAGCGAAAATGGCCTAGTTCGGCAAACTCTTTCTGACGATTTCCAGAATTTATTAGGGAAGACTCCGTACATAGGCTCAATAAAAGGTGAAATAGGCTCCGCCCATATCTTGGATCGATTCCAATATTGAAATTGACATGTGTTAGTTACACTTGTTCCTAATCCAAAATTCTATCCGAATTTCAATTACCCAAAGTCAAAAAGTCAACAAGTTCTGTTCTTATATGTGCGCGCGCGAGCGCGATCGTTTGTCTCTAATATTTGCTCATCTCTCTCTCTCTCAATCACCGCCATACCCAAAGGATTATCGCCCATGGATGATGGGATGATGTTGAAGACTGCGCGGTGGGCCCCCTATCCCCTGCCTCGGCATTCATCATGTTTGTAAACAAAAGGCGGCGGTTTGAGAAAAGAAGACAGTGAGCGGGCGGGAGAGAGTGAGGTGATGAAGGTAGTAATCGTGTGTCGACGAAAACACATATAGAGAACAACAGATTCGTGTGAAATAGATGAGGGCAAATAGGACGAATTTATTTAAGAGCAGATTATGATGCTTTGGCCCAGATGAGGGGGGGGGGGGGTATCATGAAGATGTGATGACGAACCATATCGTTCCTTCAATGTTTGTTGCTCGCTTAACCGCCGTCGCCGCAATTTAAAGGTTATTTCGACTGGGTATGATCAGATAAGAAGACGTAGACGGCTTTTCTTGGGGGGGACGTTCAGCTTTGATTCCTTTCAAATAATCAATGCGGCCTAGCTTTCTGATCTACAGGCGGGCCTTCTTTGCTAAATTTTAAGCGATTTTACTACCTCTTTGGCCCGCCCCACTTTGATCTACTTTAACTAAGCTTATATCCGATCTCGGTTGTCTTTAGCTTCATCAAAAAGTTATGAACTAACAAAGTGCGTGCCAATACATACTTCTACAATTCGGTAGTTAGTATTGCGATTTTGGATTAAAGTTAAGACAACCGAGAGGCTGTAAGCTGTTGAAGTAAATTTCTAGTTTGACTTACTCCCGACTCCAATTTTGATCTACTTTTACAGCTTATATCTCGTTTGTTTCTGGTAACAGCAAAAAGTTGCCAACTAACAAATTACGTGCCAAATATTTTTCTAAAATTTTGTAGTTGAAAATTTTTGAATAAAAGTTAAGACAATCACCGAAAGCTGTTGAAGTAGATTTCTAACAGGTTTGACTTACTCCCCAAACTTCGATCTACTTCATTTGACAGCTTTTATCTCGGATATTATTTTGGCAATATTAAAAATTTGTCAACTAACAAATACGACCCAAATATTTATCTACAATTTGGGAGTTGAACATTTATGTTAAAAGTTAATACGGCCGAGAAGCTGTTGAAGTAAAGGTGGTGCTTAGCCGACCTATATTTTTGAATTACACAACAGTTATAACTAACTTATTTTATGGGTAACACTATTCTAGCTAGTTGACTTTCAAAATCTACAGAAACTTTTGTTCCTGCCTCCACCTTTAGCAGCATAGCAAAGCGCCTATAGGAACACCTACGGCCTACACCTCATACCACCTACTCGAGTACACCTACTGCCCATCTACTGTTTGCGTACTTTCTACATAGCTTTGATGCCCGTTCCTAACCAATACTCTTTTACAGGACAAAAAGCGGCGTTGTGTGCAACGTCTGCAAACCAAATCCTCCTATCTTCCACATTGACAAGCGGCAAATCTCTGACAAGTGCACATGAGGTCAATGACACATCAGACCCGGATGAGCCGGCTGTCCGAACTTGTGGCAACCGGGGAGCTTAATGGGGAGACATGCCGTGTGTCAGTAACCAGGAATCCCCGACGATAAACAGCATCACTGAGACGGTAGGTGAGGGGTTTGTGCAGGCATCCTGAAAATCAGCTGTTTGGTTTCTGTGAAACATTTGTGCGGAACATAGTTTATTTATAGTTCAATTTGAAAAAAACTGGTTTCTGAGAGTGTTCAATCAATTTTCAATGTTCGATTCTCGATTAATAAAATTTCCACTTTCCAATTCCAGACAACCAACATCCTCTCTGAACGACCTGATGTCACTGCTCACACGAAGCGGGTCGGATGAGATTCGAGGTAAACGGCCTTCAAGTCATGACACAGATCAAAGTACGGTGACCAAGATCACTAGCCTAGTCCCAGAGTTGGGAAAATCGATAACATTGCGCTCTTCGATGACTCCGTGCGGCAGAGGTGTCGAAGATCGTTCTCGGCTTGTGGGCAGCAGATCTCAGGGATCCTTGCTTTGAACCTCCATTATGAAGAGTCCCATCGAAGATTCCGAGTGACGTGTTAAGAAAGTTCGGAGACGGCCGTTACTTGCCGCATTAGAGGAAGCACGGGTTAGCAGAGAGTTCCTTGAAGAAGGATCGCAAAGCCCTCTGCGCAATGACGATGAGCCCATGGAGAAGAATATGCGGCTGGAGAAGACACTCTGCTGCCTGAAATGGACAAGAACGGGGCAGCGTCGCAATTTCGCATAATGTTCCAGACAAATGATGAACTGCCTCCCGTACACTCATGGCACCAGGCACGTCTAGTGGCAACTTTGGATTCTCGCCAGATAAATGATCAATCAGCACATGAAGCATGCGGCGGCGGCGGCGGCGTCGCGACTGCAGCAGCAACAGCCCACACTGCCAACAACTGCGAAGAGAGCAAGAATACGCACTGATGATCAGCTCAAAGATTACGGTAAGTCGTCTTGTGTGTGATTACTGTAAGCTACGGCGAACAGGACAGACACGAGGGGGGCGGTGGAACATGAATTGCAAACAATAGGTGGGAAATGGTCGGCGCCGTGATCAAAATGAATGAGAAATGAGAATGAAGAACAAACATTGTGTGTGAGTGGTGTGTGTGAGACGAGACGATAATCAATCAATTTCTGGAAAACTACACATATATTTTCCCGGCGAACTTTCTGTTTGAGGGACCGTGCGGAACAAGACCCCCCTGAAAAAAAAAATCCGGAAAATCCTTAGCCTAAATAGCGAACGCTCGCTACTGACGCTCAAGCCTAAGCCTAAGCCTAAGCTACCTAAGCCTAAGCCCAGCCCAAGCCTAAACGGGAACCCCCTGAAAAATCAAAAGGAAGAGAATCCCAAGCCTAACGTCCAACGCGCCACTGACGCCAAGCCGTATGTCTAAGCCTAAGCATCTGCCTAAGCCCATCCCAAACCTAAACAGGAACCCCCTGAAAAATCAAAAAAGACTATCCGGAAAATCTTAAGTCTAAATAGCGAACGCTCGCCACTGACAACCGCCAAGCCTAAGCCTAATAAAGTAAGCCTTAGCCTAAGCCCACCCAAACCTAAGCCCAAGCCTAAGCCTTTCACCTTCCTAATTGTCAGGCAGGCTCTAAAAACCGCGCCTGCCTACAATCGAAGCCCTAATCTGTCCGCTTTAGCAAAATACCCTCAAGTTGGTCGGTGCAAAGGGCACATCAGTATAGTAAACGCGCTCTACTGATTATTCGAGTTTAGCCAGGTTTGGGCGCGTTTCAAGGAAAAGAACTTTGGCTCAAAAATTGTGAATTTATTTTCGAACATTTTTATATGCATCACAAAAATGTTAGTCCACCCGTTTTTGAGAAACTAACGCCCAAACGTCCAGGTATACGGTACATGCGCAAATTGCGTACAGATACCACTGGGGGGTCGTGTTTGGGCTTTAGTGTAGCTAAGGCTGTAGCGGCCCTACGGCCTAACTGCAAGCCTCAGCTTATTCGCCATAGGCTTGTCTGCCGTATTTCAAGCCGACAACAAAAAACCTTTCAGCCAATACTTCAACATCAACAACTCGCCGTCAGAAGCGATCAAGTTCGAGATGTCACAAAAAGCGAGCCTTCCGGACAAAGGCATCAAACACTGGTTCCGCAACACACATAGCTTTTCAAGGGCTTTGTTAATTTATTTTACTTCGAATATTGTTATTAGGCTCGGAGTGGAAATGAGCGAGGTGTGAACATTGGTAATTAGCCGGTTCATCTGATGAATACCCACACGAGAGGGAGAGCAAACAAGGAGAGCAATTGAGACGAGGGAGGGAGAGAGAGAAAAAATAAGAAAATCTTAATGTTAGTTGGGTGCCACGCGCTCGGCCAGGACCACCGGCCGGGAACCATTTAGTTTTGATTATGATTTCCGTCGTGGCTCATGATTTATGGGAATTGACTATTTGTGCTTGTTAGGTGATAGAATAGTTAGAGCAACTATCAGGAAGCGGACAAGTCGCAGTGCGAGACTATTAGAACACGTTCTGCAAGGTTTATTCTGATAGATTTGGATAAGTACTAATATTGGTAGAGACTAAATCGCTCTCTTGATATATACCAGCTTAATAATTGTTCTACCAAAAAAACTGTTAAAGAACGCTTCGAGATTCGAGCTTCGGGAAAGCTTAAAGGATGGGTACCGAAAAATTCTTTTTGCCTGATTCCGAATATGGATGTGGAAAAATTCAAAAAAAATTCCCTGATTTTATATTTGAGCTTTTACGATTTTCAAACCTTTTGTGCCCACCTGGTGATATTTTGGATTGATCTACGAGCTCTTGATCTACAAAAAATGCGGGAGAAGGCAGAGTACTCGACTGACTTTGGCACGGTTAAGAACGTGCTGACGTAAGCCACACTTTTTTGCGCAAAAGCAAAAAATTCCCGCATTTTTTGTAGATCAGACTGTCATGAGACAGCCAGGCACCATGTGTGTGCCTCGGTTCAATTTTCAATTTTTTAAACCAGTTTCTTTTTTTTTAGTCGATACGTTTTCTGAAAGCTAAATATTTTTTTTGCCAAAAATGAATGTAACTGGCTTAAAAAAACTAAATAAAACGATGCAAGCGCAAATGCGAATTTATTTGGGCGAATTTGAAAAAAGTGATGCGGGAATGAAATCGGAGATTCTAAGCAGGCTCTAAATAAACAGGAAAATTTTTTTGAATTTTTTCACATTGATATTCGTAATCGGAGAAAATCCATTTAAAAATATTTTCCAGATTTCGGTGCCCCACCCTTAATGAGATAAAAGAGGAAAAAAGGAGTTTTGTAACCTTTTAAGTTTTTTCTTTTTCAGGAACGCCAAAGCGACAAGGATTCCCCGTCCAACTTCAGCGTCCCTCCCCAAATGGGAATCGACTTGGTCTACGAAAAGACCGGAAGTACTGTCGCTTATGAAGCACCAAAGTCTGAGTTGAGCTCTGCGCGGGCCACACCGACATAATTCCGACTCCGATACCGCTCATGGATCGTTGAAGAGAAGAATCCGGTGCCAAACCGGACACCATCGTCTTCTTCCTCTCAGCTTGCAGGCTATGTTATCTCAGATGCAGGGAAGTTTTTTCGACGCGTCAAACTTCATGTCAGCATCAGTGAATCCGATGACAGCACTCCTTCCTACCGTCCAGTGGACGACAAGCCCGAATGGCTCTAGAATCAAGACCGATTTCCAGCTGAGATCTCTACAGCAATTTTTCGACAAGCACTACCCGAATGATGATGATCTAGAAGCGCTGACCAAGAAGCTTCAGCTGACCACGTGTGATTGTCGTCGGGTTCCAGAATGCAGAAGGCCAGAAAGATCTATGAGAATCAGCCAAATCACGAGAGTTCCGATCGATTTGTGAGAACGCCGGCATCGAACTTTGCAAAAAAGGTTTTAGTGTTGGAAATTAAAATTTAAATTTAAATTTTCCTAAATTCCAGGTGCTGCCAAGTATTCCAACGCTACTATTCGTAGAACTCATCCAACATCAAAAGAAAAAGTGCTGACGATGTAGCAGCACCTCTGGCAAGTGACAACCTCAAGAGTGTCGAAGAATCACTGACGGAAGAAGAGAAATCCCAGCTTCTAACAACAAGTAGCCCAACTAAGGAGTCAGGAGCTCCCAAAGTTCCAGCCGGCAGAGCTTTTGAAAATGATCGGAGCTAATTCGGTGACTCCATCCCGGCTGCAAGTCAGAAGTCTAGCAACGATGCCGTTCTGCTGAAGATGTGTGAATCATTGTTGGTGGGAGCATCACCTAGTACATCACCGTTCCACCAACGTTGTATTTTCTGCGAAGACTTCAAGGATTGGAGTGCGATGAGTGAGCTCATGGCTCAGAAGCGGGATCCCCAGCATATGCTTCTTCCAAACTTCGATCCATGATGCCAGAGGCTGGTCGTGCAGAGCTTCTCATGTGATCTTAAAGGACTCTGCGTTCGATCTTTGGGGCTCTTCAGTCGTCTACCGGGATTCTATCTCAACATCTCCATCTCGATCCGAAGATGATGTTCTCACAGAGGCTCTGGATGATTTTGCATTTGCCGCGTGAACTACAGCTTGCAAATTCCACAAGCGGCTCGGAAGATCTCCGGCGAGCAACAAGACGAACTCATCTCACACCGATGCAAGTGCAAATCAGTTGAAGAGCGAGTTTAACCAAGACCCCATCCATGCCATAATGTGAGCTTCTCCGCAAGGAAGTCGGCCTTCCATACAAGCGTGTTTCAACTCTGGTTTTAAAATGCGCGAGCCATATCGGAGCGAAAGACGCGCGGTGGAGTGACCAGGACTCTCGCGATCCGGAGAACTTCACTGGGAAATTTGTGATAAGACGTTCGCGACGAGTCTTTTGCTGCAAGACCAGCTGTTTGCCGAGCAGCACATTGAATTTTTAAGGAATAATCTGAAACGGGAAGGGGTCTCCGCAGTGGACGACCGCTGACCGAGTGCTCTCCAGAGAAAAAGTAAGAATTTGAATTTTTATGTAATTTAATTACATATATCATTACCCTATATAACCTTAAAAATATTCCAGAGCAAAGCTTCCGAACGACGCCCGCTGGGTCTTGCCAGTTTCCCGTTCCTCGACACGTTCGACATTCACATTTAAGGAATACCCATCGCCTTTCTGCAGGCTGTCTGATGAGATCAGGATTAAAAGCAGATCACTGATGATATGACGGCTGGAAAATCGCGAACCACGTTCTGCCAGGACGGTTGCTCGACAAGTTGAAAGAGTCGCTGCCCGAGGATGAGAAATCAAATTGACAGAAACCCAGAAAGACGTTAGCTTTTTTTTTTTGGGAAAAATTTAGAACAATTTGGCAATTTCAGGTCGGATGGGCGTGCATGTACATTTGTCTTCCACTAAGAAAAAGAAGCTCCGTGAGCATCAAAAAGTATCCCATGTGCAGTGATAAGGTGCGCAAGAAATTAGGAAACGGGCTTGAAGTTTAGCTCATAGTTAGTCGTGTCAGACTGTCTTTGATCTACGAAACATGCGGGAATTGGAATTTCAGAAAAATTGTGAAGACTCAGCAGGAACGTTATTAACCATCGACGCAAAATCAGTTGAGATGTCTGCGTCATTTCTGCCGCATTTTTTGTAGAGACGATCTACGTAGATCAAACCGAAATGAGAGGCACGTTCTGAATCCACGAGCTAGGCTTAAGCTTATGCTAAGCTTAGGTCCTTTTGTCAGGTTTAGACTTAGGCTTATGCTCAGGCTTAGGCCTTTTCTTGGCTTAGGCTTGGGCTTAGGCTCAGGCGTAGGCTTAGGCTTAGGCTTAGGCTTATGCTAGCTTAGTCTCACAATCAGTCTTAGGATTAGGCTTAGACTTAGGCTTAAGCTGAGGCTTAAGCTTAGAGCTTGGGCTTATTGGGCTTAGGCTTAGGTTTGGGCTTGGGCTTAGGCTTAATCTCAGGCTTAGGCTTAGGTTTAGGCTCAGGCTTAAACTTAGGCTTAGGCCCAGGCTTAGGCTGAGGCTCACACGTGCTCACGTTCTTAATCATACAAGATCAGCTAAGAACTCTGCGTCTTTTCGCCCGCATTAGTTTTGTAGATCTACGTAGATCAAACCGATGAGGCACTTTGAATCCACGAGATAGGCTTAAGCTTAGGCTTCCTAAGCTTAGGCCTTTTCTCTCGCAGGCTTAGGCTTAGGCTTATGCCCAGGCGTAGGCCTTTTCGCGTAAGCTTGGGCTTGGGCTTCGGCGTAGGCTTAGGCTTAGGCTTAAGCTTAGGCTTAGACTTAGTCTCACTATCAGTCTTAGGCTTTAGACTTAGGCTTCAGCTTAGGCTTAAGCTTTTATGGGCTTAGGTCTTAGGCTTAGGCTTAGGTTTGGGTTCTTACGCTTAGGCTTAATCAGGCTTAGGCTTAGGTTTAGGATCAGGCTTAAACTCTAGGCTTAGGCCCAGGGCTTAGGCTCACACGGTCTGTTTCCCACGTTCTTAACCATACAAAATCAGCTAAGAACTCTGCGTCGGTTCTCTCTGTTCGGATTTTTTGTAGATCAACGAACTTAGGATCGAGCCGAAATGAAGCACTCTGACATCACGTGGGCTAAGACTTAGGCTTAGCAGCTTAGGCTTGGATCAGGCTTAGGCTTAGGCTTAGACGTAGGATTAGGCTAGTTATAGCTTGTAACTTTTTTAAATCTACCCCGAGTCAAAAAAAAACAATTCAATTCCAGACGCTAACCATGTGCAAACCCACAACTCGTGCAAAAGGTGTCAAAGTGATTTCTGTCTTCAATCCGAGTGTGATATCTCAATTCCATCTCTCAATCCTCATACTACTACTACCACCACGACGATAACAAAACCCCCCCCAAATATCACCTCATGCATTGCATTTGCCGTCTCACTCAAGGACCTATTTCCGTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTTCCTCTCTCTCTCTTTTCTTCTCTCGAAAAAACCACAACTCCATTTTTCCGTTCTGAGCTAACTATCCCCCAAAGTAATTTCTTTGTAATATCTATATCCACTTTTTTTTCGACCACACTACACCATATCCCGCCGCCCATCCCCTCCCCCCCCACCGCTTTATGACAAAACTGGTTTCGCTTTTGTCTTCAATTTCACACCAACCGCCTGCAGCTTCTCATAATAATTAATAATTTTTTTTAGCATGCACAATGATTTTGATAAATATATGTATATAAAGTCATCTAGGATTGCCCCCTTTCTAGGATATGTTTTTTTTTGCCATCATCACACAATTTTCCGATTTCAATGATAAGGATTATATCTTTGTCCGTTGACACATGTAGATGTTCCTGACCTTCCAATTTTTAATAGATTTCCATTACTAGTTTTTTTCAGGCCTCACTATTCTATTGCAATAATTACTTGGATGCGATCCATGAACGCAGTCAATAATAGTTCAAATATTTGCACTTCTTTTTTGCACACTAATTCAAACTCACGCCAGGCTGTCCAAATACGGTTTGATCTACTAAAAATGCGGAATGAATGTTTACTCCCAACAAAATGTGACATGATCAGTTGGCACGGTTCTTTTTTAACCATGCGATCGGTTGAGTAGTCTTGCGTCTCTTCTCCCGCATTTTTTGTAGATCAAGCCAAAATGTGACACTGGACAATGACACAACGTGTAGACTAACATTGACTGACACCACGAATATCATATTGAAACTTCTTGAAATCTGTTCAAGAAAAAAGTTATGAAGGCTCAAATGGCCTAAAATTCGCTAATTTAAAAGACACTTAAAACGGTGTCTTTTTGAATTTTTCCGTCCTTTTTTTAAACATCTTTGTTCATAAAATTTAGTGCTTACAAAATGGATGTTGGAACATTTATAGGATACGTTCAATTTTGCCATTTGAAATTGAAATTCGGAAATTTCAAAAAAAAAAAAAAAAAGTGCGAAGCCAAAATTTGTTTATCCAAAAATTATCGGCAATATTGCCGGTTTGCCGGAAATTTCAATTCCAACGACAAATTTGCCGAATAATGGCCGCATCCATTCCTGCAATTTGGCGATTTGCACCGATTTGCCGGAACCAGCTAACCTACTTACTAACTTGCTAACAAGCTCTTCAAGGTTTTTAGTTGATGATTTTCAATAGAAAATTCAGGTGTTTTCAGGCAATTTCGAGAAAGCAATTCAAACGTTTAACAAAAGAAAAACGACACTTTTTCCTCTTATTCGATTCTCTTAATATCTCAATTTTGCCTTATAAATTTATCCTCTCCTCACAAGGTGACACACACACACACACGCACACACTCGTTTCTGCTGCGAAAAAAAGCTATGACCTAACACGCGCCTTCTCGCGTAAGACTAAGATCCACTGAAGACATCTGATAAGAGTGGGTCCGCCATTGTCTCCAGAAAATTCTACACGCCTCCGCCCGGTAGGGGTCCCACCTCGTCGCTTCACTTTTGTTTCTCAAAACGATTCCATCGGCTTCCGCTGGCTTGGGCCATTTTCTCTTATACAACTGGCCATTCTTCTCTTATTGCTTAACATCATGGTTATTTAGGAATTTGTTCTACCCTGACTTGAAATGACTGGACGGCCTATTTTACTTTGATTGACTCAGAAGACTACTATAAGCGGTCATTTGTTGCGAAAATTTCTGCCTTTAAAGGTGGAGTAGCGCCATCGTGGGAAAATTGCTTTAAAAGGGCGCACGCCTATGATACCACACGAATATTATGTTAGAAAAATTCAGGGAAAAAAAATTCTCTAAATTTTATATGATTTTTTGAAAACTGAAAAAATCTAATTTTCACTTAATTCTTATGTGAATTACCGCTTGGATTTGCTCGATGGAGCGCCTTGCACGTTTTTAAATCTATTATCATATTTTATTTGTACTTTGTATTTTCCACGGATTTTTAATGTTTACGGATCATCTTTTTTTCCTTGAATTTTAAAAAGTCAAAATCCAAAATGCAAATTTTCGATTAAAAACAAGCGTACAGGTAAATCAGTTAATCAATTCAGGTTCATTTTTACGCCTGTAAGCGTGCTTTTTAATCCAAAATTTGCATAAAAAAAATTTAAAATGGGTCGAAAATAAGAAAAGATAATATAAATAAACTTAAAAACATGCAAGCGCGCTCCATCGAACAAATCCAATTTAAGGAGGTATTTCAATAGGAATTAGGAGCAGCAGAAACTGAGATTCTTTCAATTTTCAAAACAATAAATCATATGTAAAATTTGGAAAATTTTGATTTAAAATTTTTGCGTCATAGAAAAACCGGAGTTCCTCGCTTTTTTTTCATCGAAATTCAAAAAAGTAGGCGTGGCCCTAAACCGAACAGCTGTTGTTTTGTTATTGCTCTTAAAATTTCACAGCCTCTAATTGGTTGAACACGCCCACTATTCTGAAATTGGCCCACCAATGACAAATCGCGAAACTTCTTGTTTTTTCCGCAGACTATGGAAGCGTCCGCACTCGGGATATTCCCGCATTTTCCGCCAGACTATGGACGCACCATTATCATATCAATTGGGTCATGCTGTGGTACTATAGGCATGTTTTAAAGCAAAATTTTTTCCCCACTGGCGCTACTCCACCTTTAATGCATGCTGCGTCTTTTTTATTCGGTTCTGGCCATAACACACAAATTTTCTCAAAGTTTAGGAATATATAGATTTAAGGAAGAAAGTTTTTAGTTAGGAAAAAATATAGTCTTCTTCATGTTTTCTTTTTTTTGACAATATTCATTCTTGCCATCCGTTTTTTTTTCTGCAACCCTATTCGATAAATGTTTGCTTGGACGATGTAAGGTGCTTTGAACACTCGGCATTAGGGCTTCTTGCCCATTAGACCAAAAATATTAACTTGTATCAGAAGTTAGGCAACTATACGTTGGCAAAACTTGGATTCAGGCAATATCAAAGTTGCTAACCCAAGTTTCACCCAATTCGCAAACTTTGGCCTAAACTTTTTTTGTACTATGCGCAGAAGTTCCATTTTCCAATCGCCCCAACGTTTGCCCATCTTTTGCCCAAGTTTAGCCAACTTCGGTCCCAAGTGAATATTTTTGGGCCATGGGCGCTAGAACATCGCCGAATGACGAGCTCTTAGAATTTTATTTGACTCTATCCGATCTGCTAATTCTCAAAAATCCCCCAATTGCCAACCATTTATCAGAATGGGAGTAATTGGGCGATAGCGCTCAACGTGCTCGGCTTTGGCCGATAGTGCGCCTGATTCCCAGAGGATTATGTGGACCTGGTACTTCCTATGAAAAGCTGTATCCACCATTTCACACGCTAAACGTTTCCTACTCATCTTGATTAATTCAGTGAAATACTACAGTCAAATCAGGTCTTCGACAATTGTTGCTGAGTCGATCTTCTACCGCACTTCATTGGTGCCAAAACTGAGACGAACTTTGATGTTCCGCTCACCTGCTTGAGATTGGAGACTAGCAGGAAGAGATGCTCGTGTGGATGTCACTTCGGTGTGATCTTTTCCCGAATAGATCGTGTTGTTCGAGTAAGTTTGCGATTCTATATGACTTGTCAACGTGGTGTCGGGCTGACCCATTACGTTTTGATCTATAAAAAATGCGGGAAGTTTATGACCAGAAAAAAATGACGTCATCACATTCTTAACCATACGAAATCACTTGAGCAATCTGCGTCTCCCATTTCTTCTCCCGATTTTTTGTAGATCTGCTACGTAGATCAAGCCGCTGAAATGCAATTATTGAAATTCCAGCTTGCTGTCTCAAAATAAGAACCAATCCCACTTGCCTGCTGGGTAAGATCCGCCACCTCCCCCACAAACCGTGATGCCAGCCAGCCTTCGGCCCTCTCTTTGCTGCCCGGCAACCCCAAACTGTTGCCCGAATGTCCACCCAGCTGCCGAGTTCGTCGCCCCGAAAGAGTACGAGGACGAGCAAGGCAACCCTGGAGGCGTCCCAGCACCACCAAACCCACCAAGAACTTGCTGTCCTCCACCAACACCTGCTCACCATCGCCACCACCTCCACCACCACCGGCTCCGGAAGCTCCAACGCAATGCTGTGGATCACAGCCTTATAGAAGAACACCGTGCAGGTCGTCCGGATGTCCGAATGGAGATTGTTGATGCGGAAGACCTTGCTGTTACAAGCGGACAGCAGAACCCCACGAATGTTGTAATCAAGGGCAAAAGGCTTGCAGCCCACCAGAACAGCCTTGCTGTCCTCAGTTGAAGCTGGATAACTGCCTCGATTCGGCCCCACCTTGCCTTCGCGCCTGTCCATCGTGCCTATTCCTGAACTGATGCTTGGGAAGAGAACTAAGAGAGACTGGGCACCGGGGCTTCATATGCCACCCAAGTAAGCTATAAGTTTAGATTTTCACCTAGTGGCAGGCTGTCTCAGAGTGGTTTGATCTACAAAAAATGCGGGAATTTCTCGCCCAGGAAAATGTAACGTCAGCATCAGGGCTGGGACCAAGAAAAAAATTTTACCAAAGATAAGTTTAAAACCAAAAAAACCAAAAAAAAAAAAACCCAAAAAATTTTTGATATGCTTAAGTTGATTTTTAAGCTGGGGTTAGTAATGTTGCAAAATGGTAATTATTAAAATACATTTATGCACAACTGTGTTAAAATACATGTTTTAATGTATTATAAAGATTAGACTCTAGTCGACACTAGACACGGAACTTTTTTTTTAGATTTTTGGTCAAAATACCAAAAAAACCAAAAAATTCCCAACAACATGTTCTTAACCATGCGAAATCAGTTGAAAACTCTGCGTCTTTTCTCCCCGTGCGATTTCGAAGATCAAACCAAAATGAGACACTTTGACACCACATGGGGTATTTTCAAAACGCTGAAAATAAGTAAAATAAATAATAAAAATTTTCAGTCGGACTCCTTGGTCAACAATCCCCACCGACTGATTACAAAGCCGGTAAAGACCATAATAAAATCAAGTGAACTCCCGCGTTGCATCTGGAACCAAGACATCTCAACTGTCCGTCACCAAAAAGCACATCGAACTATCCTCTAACCACGTCCGCGGAATCGCCTCCAACAGCCGGAAACGACTTCCGAAGAGCCCACGTTCGATTCAAGAGCAACATTGTACTTTGGAAATGGACCATGCCAGCTGTGTCTGAACGGAACTCTCAGAGAACCAAGCGGTCACTCGCTTATAGTGTTCGTACCTACCTACAACCACAATACTCTGATTGGAACCCGTTCCTCGGAGATCAAAGCCATACGACCGCAGTCGCCACTCTCCACTCGCCGGGCACAGAACTAAGAGAGCTGGCGTGAGTTTGACTCATAGAAATTAACGTAGCTGAATTTATTTTTCCAGTGCCTTCCTCATCCACAATGTACCCCTGCATGTCCGTCGCTATAAGAGAAACCGGATCGGATTCCAATATTGTGAGCTCCAGGCAATGGACACTACGGTAGGAAGAAGCGGGATGGGGAGCCGATAGAGATCTGTGCTTGAAAATACAGAAAGGTGAAGATATGCAGATGAAAAGTGTGATAACGATGAGTTCAGTATTAATGAGCGAAGCAAACGACAAGCCTACAATCCAAAAGGACTTGATTTTGGATATCGTGAAGCTCCTATCCAAGGCCTCCTTCAGGTGGCAACAATCCAGGCGGAGGATGCATGATGCTCCTAGCCTGTGTTCTGGCTCAGAAGAAGAGAAGAAAGAGAAATGAGATCGGCTCGACACGTACTACAAAGCTGTGGAGCAGCACAAGAAGCCGGTGGAAGAGTACGAGAAGGCGATGGAGGAGCACAAGAGAGTCAAGCGGCAGTTCTTCGCTCCGGATAATGCTGCAGTGTTCCTGTCGGGCATGGGTGTCACTTGCCTTGGCACTAGCAGAAAGAAGAGAGAAGTCGAGAAGGTGGAGCATATGAGGATGAGCGAAGCTATCTATCAGAGCAAAGAAGGGGTATAAGGAAGGATATGATGATGATGATGAGGTGAGAGACCTGAAACTTTAGATCCTGTAAGAACCTTTTGAAAATTCCAGAAAAAAAACCCCCTAATTGAAATTACGCCCGCACGCGCCACTGAGATACTGTATTCGCGGCGAGACCACCCTACTGCACATCTAAGAAGTCTCCCAACGCAAGTGACGAATTTGGCCTAAAATGGACTTATGGGATTTCCACAGTTTTCACCATTTTTTTGACACAGTCGACGTTGACTTTTTACACTCAAAAAATTATTGGCGTGGTCATCTCAAAACTGATTTCAACAATTTACTGGATTTTACGCGTGTACTTCATAGTGTCACACCAAAAATTGATCTGGTTCATGTGGTGTCAGCGTGTCGCCTTTTGGTTGATCTACGTAGATCTACAAAAAATGCGGGAGTTGAGAGACGCAGAGAACGGGCGCAACAATGCGGATTTTATCTTAAATTTTCATATCAGGACGACAGTGAATCCTCGGAGGAAACCGAACCCTCTAGACGCAGAAAGCAACGCCGCTCCTGCCAACAAAGTTAGCCGACGATTGCCTGAACAACGTCGAGTACGCAGTCTTCGAAAAACTGGATACAGACAAGAGAACCAAACGAGAAACCGTGTTCCGTCGTAAGAAGTGGACCGCCAGGTGTGGCTCCTTCATGGGCTCACCAGGGCCACATCGTGTCAAGAGAAACTTCGGGCAGCCTGAATATCAATGTCTCGGAGCAGAATTGCACGGCATTCCCACAGTGTCGGCAAACAGTGAAGAGACACTTTTTGGGAGAAGACTGTAACATCTGTACACAGGATACTGGTCTGAGGCGGAGGAAGAGAGTCTTCGGAACAGCGGTAGGTGTTGGTTTAATGAGCTGCCGTATCTTATTCCGCAATGCTACCCATGCCCAGGAACAAACGTTCATAACTTGAAGCGACTCCCTCCGTGGATATGTCTCACATATCACATAAATACCACCTCGTAATAATAATTCAACATGACTAATAACAAATAAGTACATACATACATTTATATTAGCTTTCAGCACCCGTAGTCGCAATGTGGTGCAATAAAGATATGTGTAAAGAAATGGGAGATGTAGTAGATTTGGTCGTTATAGTGATCGCAGATCTTTCCTCTTTGAGCCGGAATATTGACTGGATTGGAGCCAGGAGATGAACCTCGCGGGGGCAAATGATGCAAAGTAGGGGTGAAGCATTGCACTGGCTGCGACACGGCTTTCCGGGCGGAGCTGTAATTTTGAGGGTTACAAGACATAGGTGTAGCTCGATGTCGATTCATTTAGACTAGCATTGAAGCCTTAAGCTTTCGGCTTGAGCTTGCACGTACTCAAAGACACGGTTGCTGCTCAATATAGCTCGCGGAAACTGATTTGTCACAGGTAAGATAACTAGTAGGCCTGGACTGACTGTGGAGTAGCGCCAGTGAAAACTTTGTCAAAATACATACATTATGACGGTCCGAAAAAAAACTAAATTTCATAAGGGGTAAAACCAAAGAATTAGATTTTTCACAATTTCAGGTCAAAGTCTTGGCAAACTGCTCAAAATAAAAATGAGCAATTGAGGAAATCTAGAACAATCAGTCGCATGTTCCGACCCCTCCACAATATTTTAATACACATAATTAAAACACAATTACAGTATAAAAATGTATGAAAAAAAATGTTTTTTTTGGTGAATGTCGACTTCCAAAATTATGAGTGGTAATATAACAGTAAATAAAAAATTTTCAAAATTTTTTTGATTTTATTATATGATATTCGGTCTTTTCGGGAGTAACTTAAGGAGTGGTTTTACAAGTCTACTTACCTGAAGAAGCATCCCCAGAAGTTCCTGTACCAGTTCAGAATCTACGTGAACATCGGGTTCCCACCGCGATGAACGACAACTCCCGATACCAACAGTTCAGGGGTCCTTGTACCCTGGTAATGTCTTTACCTGAAATAAACATCTTTATCTCTAGATTTAGTTAGATTCCCTCACCTCCGGCCACTCGACTCGTCTGGAGTACCCCGAATGCTGAAGATCCCATATCCAATTCTGGTCCTTGGTGCCGCGGTAGTCAGAGGGGTTTCCTTGGATCCCGGGAACAAAGCGGCGCCCGTGCACATTTCAGCGAAGATGCAACCGACTCCCCTGCAATGTTAGTAGATAGAGTGTACCTTTTATAAAATACTATCCTCCTAACACATATCCAGTGAAGATGAATATGAAGTCGGTACTTCCCATGAGAACATGCGGGCGGTACCATAAGGTGACCACCTCGTGAGAACATATGTCCTACTTTTCCGCACAGATTTCGCCCTGGCTAGATCAAAGTCTGCGAGTCTTGAAACGAGCTCTCGTCCTAGCAAGTTTTGTGGTTAAATCTCTGAAAAAGTTTTTATCGTAAGTGGCCGCAACGGCGCCTCCGCCGACTCAAGCGGTCGCCGCGCCGGCCTCGGAACCCCGAAAATGTCCGGCGCTCCAAACAACCACTTTTTTGCACTACGTTGCGCACAAGGCCACTCATTTCACGCCAAGCTGCGGAACACCGAACGTCTCCCCCGCTCCAAATCACTCCCTTTCGCAATACGTTGAGCACACACAAAGCTGGGGAACTCCCATAATTACCTCTCGGCCGCTCCGAGCAACCACTTCTCCTAGCACTTCATCACACAGCAGCTTACTCATTTCACAAGTCGCCGAGGTAAGCTGCGGAACCCTGAACGTGTCCGCCGCTAACAACTCCCTTTCGCAATACGTTAAGCACACACCAACTGCGGAACCCCCAACGTGTCGGACGCTCCGAACACTTCTACGCCACTTCATTGCGCACACACCAGGTTACTCGTTTACGCCGAGCAGCGGAACGCCGAACGTGTCGGCCGCTCCAAATGCCCACCTTTCGCGCTTCAATGGCGTCGGCGTGCGGGCCAGGATTTCGCGCCTCGCTCGGATGGGAGCGCAGTATCACCACTCGGGAGCAGTTTGCAAACTAACCTATGAATCTTCTCCTATGACAAAAATCGAGTCCGCGGATTGAGAGGACAAGCTTGATGTCAATGCTATCCAACCCATAGACGTTCTGCTCCAGGTACTTGCTCAAATCCATTTTCATGTACTCGAACACATAAGTTGGTTGAGGTCGTTGATAGAAGATGTCGTGCAAAGAGACGATTGGGATTCGCATGACGGAGGTTTCTGAGAAGCGAGGCCGAATTTCACGGATAGCGGTGAATGGGAGACGTTCTTGAAATTGAAGTTTGATCTCTAGTTCAAGGCGACTAAGGGTAAGGACCTCTGAATATAATTGAGTGGTAATATCAGGTTAACTAGCATAACTTCCTTGGACTCGCACTTATACACCGTTGCATAAGAGCCTTCCCCTGTCAATTGTACAGATCATTCACATCCTGCGGTGACGTACTTCCTCCTTCGAGGAAGCGTGAGCGTATTTGGATCGTAGTATGCTGATCGTGGTCGACGTCTTCGAAGATGTGTGAAGCGGCCACAGAACTGTTGCTAGATGGTGGAGGTGGCATTCAAGGAGAGTTCACGCTTGTTTAGGGGCACGGACATGGTTTCAGATGGATTGCTTGAGCGGGAACGTGATTGCGGCTGATAGGGTATTACTAGGTTTGACTTGGAAAATTTTCTTAGAAAAACAGTTTAGCGGGAAGTTTAAATTTGCTGATTAAAAATGTTGGCGTAAGTGAATGTCGAGGAAGTACCCCATTATGGTTTGATCGACTACAAAAAATGCGGGAGGACAAAGACTTTGCAACTGATTTTGCAGGATTAAGCTGACGTAAATTTTTCCTGTGGGAAAAATCATAACCCCGCATTTTTGTAGATCAACCGCCGCAATGAGACAGCCATAGATGCCACCACGTTGACGGGATATTTAAATTTTGAGAAACTCAACATTTTGGCGGGAAGTTCAAATTTTCTGAGCAAATTTTGGCGGGAAATTGAAATTTTCTGACAAAAAAATTTTGGCGTTGGGAAATTGAAATTTTCTGACAAAAAAATTTTGGCGGGAAATTGAATTTTTGACCAAAAAATTCTGGCGGGATTATTTTCTGCGAATTAAATTTGGGTAGGGAGAAGTTCAAATTTTCTGTATTTTGCGGGAAAGTGAAACTATTGGCAAAAATATTTTGGCGGGAAAATCAAAGTTTCTGAAAAAAATCACTGTTTGGCGAGAAATTGAAATTATCTGACAAAAATATTTTGACGCGGGAAAATTTTTCTGAGAAAAAAAAATTTTGGCCGGAAATTCATAATTTTTTTTTTTATCTATGAAAAGAAAATTCTACGGACCGGAAACGGCCCAACCACGGCTCAAGAGCCGTCTCGGTCGGTAAATGTGATTTTTGCTCTAAATAATGCATTTAACGACGTAAAAATGCTTAAATTAGCCAACTGGTATCATAGGTAGTAAAAAAATCCGTTTTCTCAAAATTTTTTTCCTCTTAAGGCCATTTTTGTGCATTCCCCGTTAGTTTGCCTTGGTCCGTCGCGCTTTTCATATCCGTAGTTCACCCGTTAATGGTCCGTTCCCTATGAGGTCCAACATCGTCGTAAACGGAGAACCCGTCCCGGCTTTGCCTGTGGTCAGATATAAGTAGTAAGAGTGGTGTCAGACTGCCCGCATTGGATTCTACGAAAAATGCGGAAATTTTTCCCCCAGAAAAACGTCACGTCAGCACACTCTTTAGATAACCATGCGATACCAGTTGAAAAGTCTGCCGTCTCTTCGCATTTCTCGGAGAAAACCAAAATGAGGCACTTTCACAAGTTACAACAAACTTAACAAGGTGTCGAGACTACGGTAATTATAGTCTTACATATACAACCTAATAAGAATCTCCATTACCTCAAAAAGCTGAAAATTTATCTTATATTAGGATGTTCTGGTGTGCTTCCACTGCCGGACCCCGATTATGCCACATTCACATGATTGGAGTGCCATGATTGTGTGCGATCATTTGTTCCCCGTTTTTCGAGATCGGAGATTTCGTGGAGCCTCCTGAAAAAACAGAAATAAATGTGGAATTAATATGGGGGCTCAAATGTTTTCGGAACTAACCTCTTTTTTGGGAACTCTGGAGAGCATTTTTGTGTAAACTGACTAACTCGTGCCACCCCCCGCACCCCATAGAATAAATTGGCTAAAATTTCGAAAAAAAAAACTCGCCACCGCCGTTATTCTTGTATTTCTTCTCCTTATTCCGACTCCGACGCAAAGTGAAAATTGACGAGGACGGCTGGAACAGGATAATTGTTTTGTGTTTGTTTCTAGTGGAAGAGATGCAGAATCGCCGAAGTTTAGAGCGGGTGGCGTGAATTACTGACCTTCCGGGTGCTCGGCGAGCCGTCCACGTCCTGAATTGCGTTGGCGGCGACATTGTGGTGATCTGGAATATGTGGATCGTAATCGAAGCCTAATATTTAGGCTTAGGCTTAAGCTTAGAGTGACTTAGGCTTAGGCTTAGTCGGCTTAGGCTTAGGGCTTAGGCGGCTTAGGCTTAGGTTTAGGCTATGCTTAGGCTTATAGGGGGCTTGGGCCTGGCCTTAGGCTTGAGCTTTGGCCTAAGCTTAGGCTTAAGCTTGCGCTCTGGCGTAGGATTAGGCGTCCGCTTTGGCTTTGGCTTAGGCGTAGACTTAGCCTAGGACGCTTACAGGCACCCCCTAGGCTTACAAGAAATCATATCCAGTTACCGACCGGTGGCCTAGGATTTCAAAAAATGACCCTTTTTGAAAAATCGAATCGAAATATCGACGAATTTTGTTTTTGAGGCGTTTTTTTAATTTAAATTTTTATAATTTTTATCGGTTTTTCGATTTTTCATGAAAATACCAAACTCACCCTATGCAAGTTCGCCGACGACTTCGAATAACAGCGGTGAGCTGTGGATGCTGTATCATAGACACTGAGCACGATGCTCTCATAGGCCTCTCGGGTCCTCCTCCAGCCCAAACCTCCAATTTGGGATAGGTTATTTTTCCCCACATTTGAAAGATGGTATGTCTGCAAGTGACATGTTTTTTTGGGTGGGAAAAAAGAACGTGAACGAATAATTTGGATCAGCGGGGAATTGGGGGGGTGTAAAAAAGAAGAGCCGCTTGGAGTAGGGGTATTACGAAATGAGATATAGAGGAGCAGCCGGTGTGACGGCGGGGCGTTAATGGGTTACTAAAGCCTACACATTCCCATTTTCAGTTTGAAACAAGGAAAATAGAAGAAAAAAAAGAGATGAACAATGACTTACGGGTGGGTTCGGTGAAAAACAGGGGCAAGCAGGAAGAGTGAGGAAAATGGATGGTTGGAGGAGTTTTGGCATTTCTATTAGGCCGGGAATCTTTAGAGACACCTGGACTGTCCCATTACAGTTTGATCTACAAAAAATGTGGGAATTTTTCGCCCAAAAAATTTTCAACAAATTTAGATATTTTTTACATTTTTTCCCCAATTTTCAGCCATATTTCAGCCATGACTGTCCTATATTTTATTTTCCGGCAAAAAAAAATTTTCTCTGAAAATGTTCGAAACTACTTAATTAAGCAAGAAGGCATTTTTTCGGAGATCAATTTTGAGTCCTCTAGAATTTCTATTATCCATTTTAAAAGAGTTTTAAAATTGTAATTTTTTACAAAAATTGCTCACTTTTGCCACTTTCTAATAGTTTTCTAAACCTAGAATTTCTGAATTCTGCATATATGAATTACCCGTTATCAATAAATTTAGACAATTATTTTCATTGTTTCCAAAATTTTCAGCCATTTTTCAGCCAACTGTCCTATTCTTTGGGCAAAAAAAATTTTATAAGGAAATCGGACTACATTACACAACTTCCATGTTTTCTTCGTAGATTTAAGGTCCATGACCACTGCTTGGTGGAAAAGTTTTCCGAGTATTTAGGTCACCGATTTGAGTTGGAAGAGTTTAATCGCATTACTCCCCAACTGTGATAGAACTTCAAAAATTAATATGCAGGGACATCACTCAAATATCACATGTCAGTTTAAAGGATCACGCTGATTATCCGAGTGGGTCTCGCCACGATCCAGGTGCTAAATTTTCACAGTATTTAGTATGTACCTAGTGGCATATTTCTAAACAACACGCGCATAACATCGGAGTGTCGTTGCATAGGCCACTCTGAGAAAAACATAAACAAATGTGTGATAGAAAAATTAAACCACAACTAACGGATTTCTGATCACTCATAAGTTGAAATGGAAGAGTTTTTGCCGAACTAGGTCACCATATTCGGGGTAGATTTACGGCGCGTCGCGGCTCGACTTTGTAAAACTAAATGTATTTGTCTGAGTACACGACTTTCCCAGGCGTTGTCCGGCAGATTGTCAATGGAGCGCAACGTAAAGTTCAATGAGGAAGGCCAGAACCCCGTGACCAGGGATTTTGAAATTTTGCAGATATGAACAAAATGACAATAACTTAAAATGCATTAATCCAGCGGACAAAGGGAAGAAAATAAGTAGTGAAAGAAGTGAAAAAAAAGACGGACGGGGCTTCTCTCATAAAATAGTAATTGGTCATTCTAAGTGTGCCTATTGTCTTAATCCTTATTTTTTTTTCTTGGCTCATTTTACCTCAAAAACCAAATAGCGCGAAGAGTTCTAGAGAACTAGGCCACGCGGAGAGGGAAAAACTGTCACTGGAATTTCTACGCTAACACAAAATTTGTCCCAGCATACCTACGTGGCAGTAAAAGGAGAAAGTTCGGCCACTTTTCGGGCTATCAAATTTCCCACTTTCACCAATAAAAAAGAAACCACTTGTGGAAAATGGCCGTGCATACTAATGTTCGGTCACACACGTTTTTAAAACTTTTTTGCTCAAATTGAAGTACAGAGACCCTTCGATGGGTTTTCACTACTTAGCTACGTGTACAGAGAAAATTCGGCCACCAGACGCACTTTTATTCAAGGCCACACCTCCAAATCCTTCAAAGCTTCAAAAATTTTCTACGTGGCCGTGTACCAAAAAATTCGGCCATCATCTTTTTTTTGGGTCACGTCGCCAAATTCCTCAGAGCTTCAAATTCGAGATTTTCTACGTGGCCGCGGGAGAGAAAATTCGGCCACCAAATCATTTTTTAAGGCCAAACCTACAAATCCTTCAGAGCTCATATTTTATCTACGTGGTGCCGTGTACGAGAAAACCCTGCCACCCAATGAATTTTGAAGGCCCCACCTCCAATTCTTCAGAGATCATATTTTCTACGTGGCGTGGCCGTATACGAGAAAATTCGGCCACCAAATTCTTTTTTAAGGACAAACCTCCTAATCCTTCAGAGCTCCTATTCCCTTCGTGGCCTAGGAGAAAGGTCGGCCACCAAATTAATATTTCCACGTCGCCAAATCCGTCATATTATGAGGAAAAAAGTAAAAAATAATACTAATAACAATTGAGGACAAATTGAAACCCCATATAAAAATATAAGATACTAGTAAATGATTAGAATGAAGAGCGAATAGGAGGCCAGAGAGAGAGAGGGGAGGAAATTGTGCTGTTGAAGACCTTGAAGAGAGATGCACAGAAATAGATAAATTTGAATTACAATGGGGTAAGGAGCCGGGTAACTGTCCCCCCCCCCCCCCCCCCCCAAAAAGTGCGAACAAACGTGATGAAGCGAAGCGAAAATCCGGAGGGGGGGGGGGGGGGGGGGCTGTGATCCAGGTTGATAGATTTAGCCAAGTGTTTCGACTTTTGGCCGAGTTGAGCTCTATGAGCCGGGCTCACCGGAGAGAGCCCATGGAGCCCCATGAAGCAGAGGGTCACGAGGTTTGAGACTCCGGGAGATAGACTGCACAACGTTCAAAGACTAAAACTTTTTTTTTTTGCTAGGTGAGGCATGAAATATGGAGCTTTTTTGCAACATAAAATCCAATTTTTGTAAAATAAGGTCAGATGACGTGTGTATAATCTGGCTGAGAAAACCTGAAAATTGATCTACCTTAATAAACAGGGCGCGGGTGTAAAGCCGAGCGTCGTTGTGATGCTGAATTATTGTTGAACGAGTTCTGGAATTCTGGCCCTCATAAATTAAATGGAAGACTTTTTGCCAAACTAGGCCAGGCCATATCTGGGGTAGATGCGCGCTTTTTTTTGGGCATAAAATTCCCGCATTTTTGTAGTTAGATCAAACCGTACAGCCTGACATCACGTGTTTTTGGCCCCGCTAAACAGGGCGCGGGTGTAAACATTCAAATATTATGTTAAAAAAACGCATGAATTTGAACAATTTTGCGTAGAATTTTTTAACAAAAACATACATTGAATAACTGATGCGAAACGAACAGAACTGCGTAAATTTTCTGAAATTGAAGGACAGGGGAAAAAAATTGTGAAATTTTGGACATTTTTCCCTACGACGCATTGAGCCACCCAGATGAGCAAATAAACCGGGGGAGCAGGAGGAAAATGGAATTGACAAAAAAGGCGGGTGAAGGAGGAGAAGCTCACGTATTTAGTATCCCATAGAAAGAGTCAATTTTCATTAAAACTGCGACAAGTGACTACCAGGGAGCAGTTGCGCTCTACCGACATAGTCAACCAAGGTCCACGTAGAATATGCCAGTCTGTCCCATTACGGTTTGGTCTGCAAAAAAATGCGGGAAAATTTGGCTCAAAAAATGTGACGTCAGCACACTCTTAACCATGCGAAATCAGTTCCCACATTTTTTGGAGATCTACGTAGATCAAGACGAAATGAGACACGGCACCACGTAAAGGTCCTTCTTACAGAGTGCGCTGGAGAGCGATTCAGGTGCCAGTTTTCTAAAAAAAAAATCTAACATGAGCGAAAAATGTGCGTCAAAAGTGGAGTTTCCTTTAGCGATGTAAAGTTTGGAGAAAAATTGAAAACTGTGGAGGAAGAAAAACTATTCGCAAGACCGATTAAATAGTATTTCACTTCTTTTATTTTTCAACTTTTTGCAATTGCTTTGGCAGGAATGGGGAAAAGGAAAAAAAAACGAAATCATCGATAAAAACACCACTAGTCCACCCAGAAGTAAACCTAGCTTATAGAAATAGGCCACCCTGTATGGAAGAATTTTAGGTCATCGCGTAGAAAAGCTAGGCCACCCTGTTGAACTGCTACGCCACGGTGTTGTACACTTAGGCCACTCTGAAAAAAATCTAGACCTCACTGTAAAAAATATAGGCCGCCTTGAAAGAATTTTAGGTCATCTTGTAGAAATTCTAGGCTACGTTTTCGAAATTCTACACCACTCTGTAGAAAACTTGGGTCAGCTACTACTCGACATACTAGGCCACCCTGCAGAAAACTTAGGCCATCTGCCAAAATCCTAGGCCATAGAAAATTTAGGGAATCTACCAAAATTTTATGCGACTATCTGTAGAAAACTTAGGCTACCTCGTTCAACCATGTTCAAGGCCACCGTGTAGAAATCTTAGGCTACCTCGTTAAAATTCTAGGCCACCCTGAAAATTACGTGATCTACCAGAAAAATTCTATGCCCAGAAGTAAACCTAGGCACCTTGTATAAATTCCAGACCACCCTGTAGAAAACTTGGGCCATCTACCAATACTCTAGGCCACCCTGTAGTAAACTTGGGTCATCTACCAGAACCGAACCTAGCCTGTTCCGTTACGCCGCATGCTAAAAAACGCAGTCCAGACCTCCCTGTAGAAAATCTAGGTCACTCCCTACAAAACCTAGGGCACCCTGTGAAAATTCTACACGTGAAAATTCCCTTCCCCAGAATAAACTAGGCCACCCTGTTAAACTCTTGGGCCACTCAGAAAAACTAGACCACCCTTATAAAAACCTATGGCCTAGAAAAAAGCTTGGGAAATTTTGTGGAAAAAGTTAGCCGAAAAGGAAAATCTAGGCCGCCGACAAAAAAGCTAGGCCACGTGGCAAGAAACTTAAGCAGTGACGAATGATACGAGAGGCGTATGTTTGAGGTCAAAAAGGGAGAAAGAAAAAAAGACGAGGCGGAATGTTTCTTCTTTCATTTCAAAAGAATCTCCCCGTCTCTCGGCCACCAATACTCTCACTACTACAACTAATGTTTTTAGGCCCCCCCCCCCCCCCCCCCCGGGCACTTAGCTTTTTTGACGGAAGATGCCACAATCGAAGAGGAAACCATAAAAACCCGCCAACGACCTACTCCTTTTTAAGGCCCGGATGCCCAGATGTATGAAAAAATCGGAGAAACTGAAGGCTTCTCCCTCCCCCCCCCCTCCCTTAAAAAATGATGAATTACAAATGGTGCCGCCCATGTTGACAGTGTTTGCTTTCCCCGTGCTCCGCCAGCTATCTAAAAATTCGGGGGAACATAACAGCCACCTTGAGTTACGTATACAAAGTGACAGGAGGGAAAGATAGAGGTGAAAGTGCCAAAAGGTAGTCGAGTGGTTCGAACAGGGTTTGCAAAATTTGGGCTGTGCGCGGCGCCTTAGACTACTGCGCCACGCGTGCGAACTGTAAATAGGACTGTCAGGCAAAATACGAACGTTCGGTTTTTAAAATCGATTGGCAAAAATGAAATGAATGAAGACACACGAATGACTCATAATTTTTGCATAAAGCGGCCTGGGTCTGGGAACTGGCGTTGAATTAAGCTAAATGAAGGAAAATTGAGGCATCTCCCGTTGAGTAGAAAAGTGAAGAGGGCGGCAAAAAGAGATAGGGGGGGGGGGGAGGACCCATTCATTTTACACTCCACACTCCACACTCTGACTTTTTGATACGAAGGACATGAGTACGAACACGCGAGCACAGAAATACGACACGTTTTCTTCTCATTTTTTTCATTTTGCAAAAGGTGATGATGATAATCGCTTCTAAGAAGAACGAGGGGAAGTGTACTAAATACTAAAATTGCGAGTGGATAAATTGAATTTTTTTATTTTCGGCTCGGCAAAACCTGAAAATCAGTCTGGAAGAGTTTTGGCTAACTTTTTGTTTGTTTAGAAACTCACTTTTCGCTGCGAAACAACCTGAAAGGATATAGTGGGCATGCACCTTTGAGCGCTACAGGCCTGTGGAGGGAATTCAGTATCTCTTGGAAGTCAGATTTGCCGATTGTTTTAACGCAAAACCTGAATTATAGAAAAGAAAATATGAAAATTTAAATATAATGTAATAAATTAAGCAAATTACATATCAACTGAGAAAATCTCCTGCTTGGGGAGAGAAAAATTTGTTGAAAAAAAGCCAGAAAATCGGCAGGAAAGCAATTATCGAGCAAGATCCTTTTTTAGGTGCAGATATCGGTTAAAAAGGAAAACACTATTTTAGCTTTTAACTATTTTGTCTTAAGTTCAATGTTATAACGCAAGAAACGATATTTCTCTGGCATAAATTTTAGGTCCTAGAAAGCAGATTTTCACGTAGATTGGTCTGAAAATAATATTGGAGTAATTTTTATTATTTTTCCTTGCATTATAAAATTACTTTTATTTCCCAAGTCTAAAATATTTTCCCGTTCTTTTATATCTCGCGCTTCTCCGGGATGTTGCATCCCATTCGACAAATGTGAGGAGTCTCGGAGTCGCTGCAAACGCGCTCCACTGGACACAGAAAATAAAAAACCAATAAATTGTTCGAATTTATGCAATTTTCTTGTAATTTTCTCTGTTTTTCGTTTTCTGCAAAAAAGACAAAATTTACAGGTAGCAATGGATGGGGGATTCATATCAAGGGTTATAGCATATGTGTAAGGCTAAAAACTAGGAAAAACTAGGAAAAACCCATGGAAAAATAAAATACTCTGAAATTTCAAACTGCTTTCAGAGCCTGGAATCAGCAGGCGGCTTCACAATATCAACAGCAAGGACAACAGAGTACCCGTAAGGCTCGAAAAAAATTCAAAAAATTCCGGGGAAAAAAATCCATTAAAAAGATCAAAATTTTCAATTTTTTCAGCGGTAGTGAACCCGTACGCGGCGAATCCATTATGGGTACGCGGCAGCACAGCTTCCAACCACTCCACCACCGCTAGTATGCCTTAAAATTGAAGAAAATTTGATTAAAAATTGAAAAAATGCAAATTTTCAGGTAGCCGATCCATACGCCGGCCAATTTCAGACAATTTCCATCTCAAGCCACCAAAATAGCGCCCAATCCCTACTTTAAAAAGCCACAAAATCAGCAGCAACCAATTTTCGCCGTGTTTTCCGGCTGCAAAAAAATTAAATTATCGATTTTTTAAAGGCTACGACGCGGCGGTCTACAATTACTCAGCAGAACACTCCGAAAGAAACCAACGGCGGCGGCGGCCGGGAGAGACAGGGATCTGGGGATATTAAACAGTACTATTGTGACGTAAAAAACGTGGAAAAAATCGAGTAAAACACAGTTTTTCAAAAACCTGAGAAGTTCCGTAAAAAATCCTGTTTTTTGACTAAGGAAAAAAATCGGGTAGCACTTTTAGAGATAAACGAAAGTGGGATAAATCGAATTTTGGACCTGATTTTGGGCTTGAAAGCATGATTTTTATCAGAAAACACAGTTTGTGTTTTTAAAAATCTGAGAAAATTTCTATTAAAAGTCTTGTTTTTGGATGTTAGCAAAAAAAATCGGGTTTACTTCATTTTTAAGGGAACAAAAGTGGCCAAAAGTTAATTTCTTGTAAATTTTCACATGCAGAATATTGAATTTATTAGGTTTTTTCCAGAAAAGTAGTTTTTTTTTCTACATTTAAGGCTTTTAAAACTGAAAACATGAATTTCCTGAAGAGGAAAATCGACAAAAAAACCCATCTTTTGGCCAAATTTAAATTTTTGAGCAAAAAAATCGGGTTTGCAGCACTTAAAGAGAACTGTAAAAATTCAATTTCTTGGAGAAAAAAGGAATTTTAACACCTAGCAAAAAATTCGGGTTGTCAATTTGTTTGAAAAAAAACTTGAAAAACCGGATTTCCAGTTGTTTTTTCATGATTCTCAAAAATCTCATAAAAGGAAATAATTTCGAATTTTTTACTGAAAATCGCAGAAAAATTGAAACTTTTTTTTCAATTCCGATTTAACAAACATTTTTGGTACGCTAAAAAACGGAATTGATTTTTAGCCTTTTAAGTTCGGAAAAGATGCTGAAGATCGAGTCGGAATTTTCTATTTAAAGAAATTTGTGCTGAAAAATTGATTTTTGTGCTCCAAAAACTGGAATTTTTGAAAAATTCGACAAAAAAATTTTTTTATTAGTAATTTTTTTAATTTTTCAACCCGCTTTTTGCCCAATTTTATTTTATTTAAAAATCGGGTCTACTGAACTTTTAAAGGTAGAAAAACTGCAAAGAGTTAATTTCTTGGATATTTTAAGGCGTTAAAGTCCAAATAAACATGTTGAAAATGGAAATGTCTACAATTGGTCGATTAAAAAACATTTTTTTCGCTAAAAAATTGAATATTTTTAGGCTTTAAGTCCAAAGAACAAGATGAAACTTGAATTTTTTTTTCAATTTAAAAAAATTTTGCTCCATGTCAGGCTCCCAAACACTGGAATTTTGGACTTAATCGAAAATTCGGACAAAAAAATATTTTTATTCGTTTTTAATTTTTTTAATTAAGAAAAATCCCAATTTCGAGGTGTGAGCAAACTCTCGTGCATTTTTGGGGTTAAATTGGAATAAATTATCAAAAATTTTCGAATAAAACGGATGGAATAAATCTGATTTTTGTAAATTTTTCGAAAACAAAAATTTACGTTGTTGGCAAAAATTAAATATCTCATGGAAGTCCAAAAACCATGTAGATAATTCGGGAGGAAAAAAATTGGGAGAAAAAAATTTTTAATTTCAGTAATTTGAAAAAAATATTTAAAGCTGGTGTAGTCGACTTTATTTATTGCTTAAGTAGACTCGAAATTGCCTAGAAATACCGAATTTCATAATGAAACTTCTTGAAAACTTCTCACAAAAAAAAAAGTTATGACGGCCAAAAAATGGACTATAATATAATTTTGAAATTTGAGCGACTTTTCAAGCGGCTGGAAACATTTATTCGCTTTTGAAATCACCGTCAAATTTTGAGTATACTGTGCATTTATGTTGCGTGTTTTCAACTTCATTTAGGTATTATAAAGTCAAAGGGCGGCGAGATTTTTAATTTTTAGTGAACCTGACGACATCGACTTTATCTCAATCGAGTTCAAAACTCAAGATAATTAAATTATATTATCAAAATTTGACGGTGATAAGTTGTAAAAAGGTAGTTTCTAGCCGCTTGAAAATCGGTCAAGTTTCAAATTTTAACCAATTTCAGGCCATTTTTTTAGTCGTCATAACTTTTTTTCGAGAAGTTTTCAAAAGGAAGTTTCATTTTGAAATTCGTTGTTTTCATTTTGAGTCTTATAAAGCTTTTAATAAATAAATTCGACTACACCGCCTTAGTATAAATATTTTTTTGAATTTTTTTAAAATTAAAATTTTTTTTTCCAATTTTTCGATTTTTTCCGCATTCTCCGTGGTTTTTGAACTTCCAAGGCCTCAAACAATATTCAGTTTTCGAAACTATTTTTTTTTCGAAGAAATTCCTATAAAAATCAGATTTATTCCATTCTTACTCGAGCAAATTTTTGATAATTTTTTCTTTAACCCTAAAAATGCATGAGATTTTATCACACCTTGACGCTAATTTGCTGGAAGTTATTTGTAGAATTTTTGGAATTATTAATTAAAAAAAAGTTTTTTTTTTTTTTCCGAATTTTCTACATGGTCTTTGAACTTCCAAAGCCTGAAAATGATTTTAAAAACTTTTTGCTTTATTCGGTTGTTTTTGGTTTTTTTTTTTAATTTAAAAAAATTAAAAAATTAATAAAACTATTTTTTGTCTGATTTTTCTATTAAAGTCCTGTAAAAAAATTCTATTTTATAGGTGTTCAAAAAATCCTAATTTTCAGGCCGTTTTTTGGCCTTGATATTCAATTTTTACACAAAAATTTTTTTTGCAGTTTTTTGCCTAAAAAAGCCCTCGAACAAAAAAATCATCTTTTCTCGAATTTTTGGAAGCAAAATTAAAAATTTCAAAAATATCAATTTTTTGGTGTTTTTCGGGTTTTTTACATAATTATTTTTTCATTTAAAAAGTTTGTAAATAACCATAAAATTTATGATTTTTTAAATTAAAAAATAATTATTAAAGAACACTCGAAAAACACCAAAAAATTGAATTATTATTTCAAATTTTTAATTTTTCTTCCGAAAATTCGAGAAAAGATGATTTTTTTTCGACGATTTTTGAGGCAAAAAACTCCAAAAATAAATTGTTTTGTAAAAATTTAATAAGGCAAAAACCAGGCTGAAAATTCGGATTTAAAAAAATAATTTCTTGCTATAAAATAGATTTTTTTCAGGACTTTAATCGAAAAATCAGACAAAAAATATTTTTATTATTTTTTAATTTTTTTAAATTAAACAAAAAATCAAAAATATCCGAAAAAACCGAAAAATTATTGAAATCATTTTCAGGCTTTGGAAGTTCAAAAACCATATTGAAATTTCGGATAAATAAAAATATTTTTTTGTCCATTTTCGATCAAAGTCAAAGACTTCCAGTTTTTGGAGCCTAAAAATAATCAAATACTGAGCAATATCTTTTTAGATTGAAAATGAACGACAAAAAAGTTTCAGCTTGTTTTTTGGACTTTAAAGCCTAAAAATTTTTTCACTTTTTTAGCGAACAAAATGTTTTTAATCGAACAAATAGAAGACATTTCAAATTTCAACATTCGTATATTTGGACTTTAAAGCCTACGAAGAAATAGAAATTAACTTTTAGCAGTTTTTCTACCTTTAAAAGTTCTGTAGACCCGATTTTTTAAATAAAATCTAAATTTGGGCAAAAAGCGGGTTGAAAAATTCAAAAAATTTAATAACTAACAAAAATATTTTTTCATGTCCGAATTCGTTTCTTCCAGTATTGTGGAGCATAAAAATAATCGACTTTTCAGCACAAAAAAAAAATTTGTAAACAGAAACATCAATTTTTTCAGCATCTTTTCCGAACCTTAAGGCCTAAATATATTCAATTCATTTTTAGCTAAAAATGTCTTTTAAATCGGAATCGAAAAAATTTCAATTTTTATTTACAGTAAAAAATTCGGAATTTTTTTCCAATTGTTATGTGATTTTTGAGATAAAATCATGAAAAACCAACTGGAAATCCGGTTTTTCGAGTTTTTTTTCAAAAAAATTGACAATTTTCCCGAATTTTTTCACGCTATTTTTGGTAATTTTTTCTCCAAGAATATCGAATTTTTTCAGTCTTTAGCTTTAAAAGTACTGCAAAAAACTACTTTTTCTGGAAAAAACCTATAAATTCAATATTTTGCTTTTTTAGCTTTTTCCTTTTTTTGTGAAAATTTAAGAAATTAACTTTTCGCCACTTTTGTACCCTTAAAAGTGCAGTAAACCCGATTTTTTTGCTGAAAAACTTACAAAAACAGGAATTTCGGTTGAAATTAAAATTAGGACAAAATAAAAATATTTTTTTGTCCGAATTTTTCCAAAATTTCAGTTTTTGGACCCTAAAAATATTGATCAATTCTTTAGCGAAAATTGTTTTTATTTTTCAAAAACATGCTACGACTACACCACAACTCTGTCAAAAAACCAATGCTAATTAAATTAGAGAAATTCTTCAAAAAATCCCCAAATTTCCAGGTTTGCAAAATCTCGTGCGCCGGCGGAATCACATACAACAGAGCATCTGGAAGGTCAACGGCACAAGAAAAAGAAGCTATGGCAAAACAGGGCATACCGAGCACTTGCACACCCTCGCTAAAAGATTGTCCTATCGTTGTGACCTATGTGACGTCACTTGCACCGGTCGTCTAAGGGCACGTATTCGACGCTCACGCTCATGGCGGAAAACACTTGAAAACTGCACAATTGCACAAAAAAATGGGAAAACCGTCCGCCTGAAGTCGACGTTCCGACGATTATTGCCGGGAGCCGATGGGCTGACGTAGACGTTTAAAGCCAAAGCGAAATGGCATAAACAAGCTCTGCCGGAAAATGTGCGGCATTTGAAAAAATAATAAAATGTTGGAAAAAAACGAGAAAATGCACATTTTTAGGCTCAACAAACTGAAAATATAACGCAAAAAAATTTAGAAAAGGATTCTTAGGAAAAAATTAGCGTTTTCTCGCCAAAAATGCTCACTTTTCGATAAAAATGTACATTTTATTTTTTAACTTGAATTTTTAAAAATATTTTAGGGCTCAAAAATGTCGTCTGTAAATTTTGCAAAAAAAATTCTAAATAGTGATTTTGAAATTTTGAGATTAACCTTCGCCAAAAAAAAATTTGAATTTGACAACTTAAAATGCTCATTTTTCGAGGAAAATGTAAAAAATTTTTTTTCATCTGAAATCTGTAATTTAAAAAATCATTGATTTTTTAAAAAATTTCTACTGTAAAATTTTGAAAAACGGTTGAACGACGTCAAAAAGAAGGACGTAAAAATCCGAAAAAAAGCAACAAAGAACTAGGAATTTTAAAATGTCCAAAAATGGTCTGAAATTTTGAGAAATCAAAAAGAACAAGTTTCTTTCCGTTTTTTTTTAAGCAAAAAATCGTATTTCTAGTCAGAATTTAAATTTAAAGCATATTTTAAACTTTTAAACGCAAAAACATTATCTTTTTCTTTAAAAAAAGACAATTTAAACGATAGCATTTATTAGCTTTTTTCTCAACATTGCCTGATAACACATTACATAATGAAACTTCTTGAAAAAAAAAAGCTCTCAAAAAAACAAGTTATGATTGCTCAAAAAATGGCCTCAAATTAGCTGAAAGTTAAAATTTGACCGACGTGTCAAATAGTGCGGCTGGAAACTATCTTTCTTTTTTGAGATCACCGTCAAATTTTGAGTATAAAATGTAATTATCTTGCGTTATCACCTTTGTTGATTTAGGTATAACTAAGTCGATGGACGGCGAGACTTTTAAAGGTGGAATACCGATTAAGACTTTGCTTTTTTAAACCATTTGGGATGACTTATCGGTGCGATACTGCAAGCCAAAGGTTGAGATAGCTAAAAATATATGGATACGCCGTTTTTTCCATCAGATAAACTTTGATCGGCCATAACTTTTTTATTGGAAAATTTTCAGAACGTCTCATTACGAAATTCGGCAGTTTTGTGGCCATTTTGGGCCTAAAAAAGCAAAGTCTTAAATTTCGGTACTCCACCTTTAAAAATCTCTCCGTCCATCCCTTAAAATACCTAAATCAAGTTGATAACGCAAGATTACATACTCAAAAATTTGACTGTGATTTCAAAAAGAGTAAAAAAAGTTAGCCTCTTGGCAAGCCGTTGAAATTTCAAAATTCCGCTAATTTGAGTGCCAACACTTTTTTGAGATCATAACTTGTTTTTTTGAGAACTTTTTTTTTCAAGAAGTTTCATTATGAAATCGGTGTTTTCCGACAATTTTAAGCAATAAAGCAATAAAAAATTAGAATATACCACTTGATAAAAATTAAAGATTTTAAGTTTAAAATAAAAAAATATGTTTCTTTCCGATTTTTTGATAGTTGAGCTAAAAGTTTTGGCGGGAAATTCAAATTTTCTATGTTAGAAAAAAAATTGCGGTGAAAACTCATGTGAACAGCACAGAACGGCTGCTTATGAGTATAGGTGTGAAAGTGTCTCATTTCGATGGTTTGATTTACTAAAAAAGCGGGTAATTCCCACAAATGACGTCAAGATGCTCTTTATTATTAAATTTAATTAAAAGAGAGCATGGTGAGGCGTAACTTTTGGGGAAAAATTCCCGAACTTTTTTTTGTAGTTCAAGCCGAAATGAGACACTTTGACACCACCACTTTCAGACAAAGTCCCCCACTTATTTGGTAAAACTAGTTCAAAACCCGACTGTAGTACATTTTTGGCAGAAATTTGAAAATTTCAACTTAACACCGCTCAATTTTTCCAAAATTTCACAGTATCATTTCAATTATGGTTTTGCTTTTTTAATTGAAAGATATATTTACAAAAATAGAGGACCATTTTTAGTAACAATTTTTTGGCGCTCTCAAATTACACCTTTAGTCAGAAAATTGCAATTTTCTCCAAACAAGTGATTTACAGATTTATTTTACCTAAAATTAACAAAAGATCGAAAATATTAGACTCCCGCTTTTTTTTTATTTCAATTTTTCCAATTAAAACACAAACATTGAGCATTTCTAGTTGGCACATACCAAATTTATAGGCGAAAAATTTGATTTCAAAATGTCAAAATTCAGAATTTTTTTTTGCTAAATGTTCAGCACCGATTTGTGCGCAAAAATATTTGAAAAAAAAAAAAACTCGAAAATTGAGCATTTTCAGTTGTAAAAGTCAACTTTTAGGCGGAACAAATGTGCAATTTTTCCCCAAAAAATCCAAATTTTCCATTTTCTATCAAATAAAGCACTGAAAAAATTTGTTATACCTAATGTGGAAAAAGTGAATTAAATCAGATTTTTTGAAAAAATGCACTTTTTTTTTTGCCAAAAATAGTTCCCCGACTTTTTGTTCCAGAGTTTCCTCACCAGGTCATCGGTATCATCGGATAAATAAATTTTGCGGGAATAATTGCGCTTTTTTTGTATATCAAACCGAAATGAGACACTTTTACACCCCACTTCAGGCAAACGACTTTTTTCCAGAGTCATCGGCATCAACACGGTAAACTTCGTCGGCGGTAGGAAGCACTCCACCGGACAACTCGAGGGGAAGAAATACAGCGCGATCCAGTTGCTGCCGCCCTGAGCTCACTCGGTGCCTAAGGAAAACCGTGGTGCTGCTGCAACGACGACGATTGAACGGTGGAAGACGAGAAGCTCCGAGCAATGATCTCAGGAGGTACAACCTGTCGCCGATGTACATGTCACTGAAACCGTGATGCTACCGGAAAACTGGTGCAATTTCCATAAACCGTGCGATTGCAAGTTTTCCGATCCGAATGCCAAGGACATTCATATCAGGTGAGTCGTCATCGTGTAAGCTATCGCAGAAGATTGATCCGACGTTTGGTGTGAAGCCACCGAACAAAAGAACACAGGAGAAGCGGAAGAATCAGCTTCCAGCAGTTCATGGATTGTGTAGATTTTATTTACACTAAATCAACAACAACACAAAAAACATGTTCCAACAAAATTGGAAAAAAAAATTTTAAAAATCCCAAATTTCCAGGTGTCTAAAACCCATCCCGTGCATACAATTTTTAGGGTTAAAATTGGAAAAAATCATCAATTTTTCGGATAAAAATGAAACACAATCTGATTTTTATAGAAAAAATAATAATTTGTTGGCAAAGAACTACTTTCAGGCTTTGGAAGTTCAAACTTTGTAGCAACATAATTCAGAAAAAATCGAAAGATTGGAAGAAAAACATTTTTAATTTGAAATAAAATTCAAAAAAATTTAAATTTTTTTAAAAATTGAATTTTTGAGTAAAGAATTTTTTGCTATAAAATTTCAATATTTTTCAGGCTTTCAAGTCCAAAAACCGTCCGTTGAAAATTCCGAAAAAATCGAAAATTGGAAAAAAAATTTTAATTTAAAGGTGGACTACTTGCTCTGTGGGGGGAAATTGCTTAAAACAATGCCTATGGAACCACAATGCCCGAATAGCATAATAAAAAAATTTTAAAATATACTCTAGATTTTATATTATTTTTTGAGAATTGGAAAAATCACAGTTTTTGCCTAATTCCTTTATGAATTACCGCCAATTGGTTCAGACTGGAGCGCGCTTGCATGTTTTTAAATTTATTTATTTTATTTATTCTTATTTTCCACCCATTTTTAATGTTTTCGATGTATTTTTATTTGAATTTTAGCAGAAAAAGTCAAAATAAATACTAATATTAAAATGCACGCTTACAGGCGTAAATCAGTGAACGATAATAATTAACTCAGGTTCGAAATCGTTCAAAATCGTTTCTTTTTCATTTTTACCTGTAAGCGTAGCTTTGCCTTTAGTCGAAAATTTGCATTTATTTTCACTTTTTCTTTAAAATTCAAGCAAAAATACACCGACAGCATGAAAAATCGGTGCAAAATAACAAGAAATAAAATAAATAAATTTAAAAACGCACTGCAAGCGCGCTCCATCGAACAAATCCAATTGGCGGAAATTTAATGGATGGGAATTAAGCAAAAACTGAGATTTTTTTTTTTCAAAAAATCATATAATATCAAAATTTTTGTTTTTTTTTTAATTTTTTTAAACATGACATTCGATCATTGTGACCCCATAGGCATAAAGGTGGTGTAGTCGAATTTTTTCTATTTCTTTACTAGACTCAAAATTGTCTGAACGCCGAATTTCATTAAGAAACTTCTTGGAAAATTTTCAAAAAAAAGTTATGGCGGCTCGATGGCCTATAATTAGTGAAAATTTGAAATTTGACCAACTTATCATTGTCGCATCGACTGGAAACAATTTTTTTTTTGAAATTGTCGTTCAATTTTGGGTGTACAGATCGATATCTTGCGTTTTCAGCTTTCTCAAGGTATTTGTCGATGGACTTCAATTGGATCTGTCAAATTTTTTACCAAATCTCGTCCATCGACTTAATACCTAAAAGCTGAAAACGCAAGATAATCGACCTGTATACCCAAAATTGAACGACAATTCCAGAAAAAAATTGTTTCCAGCCGCCGCGACAATGATAAGTTGGCCAAATTTCAAATTTTCACTAATTTTAGCCCATTTTCCGAGCCGCCTTAACTTTTTTTTTTGGAAAAGTTTTCAAGAAGTTTGATTATGAAATGTCTTCAGTGTTTTCAGACAATTTTGAGGCCAGTCTAATTAAGCAATAAAAAAAATTCCTGACTACACCACCTTTAAAGCAATTTCCCCACTGGGCGCGACTCAACCTTTAAAGGGGGATTAGAGTTTGTGGGTATTTTGCTTAATCCATAGACTAAAAGTGCATTCCAAAAACACCGAAGTGATTTCATAATGAGACTTCACAAAAAATCTCCAAAAATTTTTTATGGCCGGTCAAAATTCGAAAAAAAAAGATTGCGCAACTTTCGCGAAATTTGATATTTCGCACACTTTTCTTTGTCTAGCAGCCGATGGATTTTAGTTTTTCTAAGAATATCACCCTCTATTCCTTCTTGGTAATTTATCTCGCGAAACGAATCCGTTGATTGAGACAACTTTTAGGCCGATAGGCATCCAAAAATGCTCAATATAGGGATGCCTAACGGCCTAGTTGTGTCAATCAACGAATTTTCGCGAGATAAATCATTAAAATAAGGATTAAAGGGTGATAATTTCAGAAAAACGAAAATCCAGCTGCTGTGACAAAGAAAACTATGACCCGAAATTTCAGATTTTAGCGTTGCATCTTTTTTTTCGAAATTTTTTATTTTGACCGGCCATAAAAGAATTGTTGGAGATTTTTTGTGAAGTCTCATTATCAAAATATTCGGTGGTTTTGAACCAGTTTTAGTGTATTTAAGCAAGAATACCCACAAACTCTACTCCGCCTGATGATTAAAGGAATGAAAATAATTCTTGGAACGTTTGGTTTAATTTTTTGTTAAAAAATCCACACCGAAGAAAAGTCCACAGTATCAGAGCCTCCGAGCTTCATGAAAAGCCGTGGTTCGCCCCACCGTGGCTCCAGAAGGCCGGGAATTCAAAATAGTAGATGATAGAACTATTAACGAAAAGTACTCGCCGGGCTTAATCCGGGCGTAGAGTTCATTTATGAGGATCGACATCCTTATGTCTGATATCAATCTCTGGGAGGAATGTGTAGGATAATATCGCAGCGAGACGTTCGGACCCTGAAGACGTGGTGGAGCGTCCCACCACCACCTACCACAACGGACGCCGCAGACAGTGTTGGGATGCTCGAGAGTTGGAATTATTGCGAACGTTCATCAAATGACAGGGGATCGGTGTGCGGATGTGGTTCTGACGTGTACGCCGGTGCCGACTTCGGGTTGAGCAGGATTATTTAGGCGGTTGTTAGGAGAGTCGACGGCACGGGCCGGGCTTTTTTTTTTGCCGGAAAGTTCGGGATTTACCGGTTTGGGAACGTTTTTTTTTGCGGCAAATTGCCGGTTTTCGCCGGAAATGTGAAAAACGGCGCAAACCTGACAGTCTAGCGGGAAATTTTCAGTTTCGGCAAACTACCGCGATTTGCCCAAGGATCACAATCGTCCGGCAAATTCGGTAAGTTGCCGGTTTGCCCATTAGCCGGTTAGTTGAATTTAGCAGAGGAAATACGGCAAACGGCAAGTTGCCGGTTTCCCACGACTTACCGGAAATTTGAAAAACGGCAATTCGCCGGTTTGCCGGAAATGTGAAAAACGGCAAATTTCAGAATTCGGCAAGGCCGGTTTTTGCCGGAAATTTTCATCTTAGGAAAATTGCCGGTTTTTGCCTGAAATTTTCGTTTCAGTCAGGGAAAATTGCCGGTTTGCGGGTTTGTCGAATTATCCGGAAATGTGGAAAACGGCAAGTTCCCGGTTGGCTGATTTGCCGGAACTTTTTAATTTTCGGTAATTTGACCGATTAGCCGGAAATTTTTTAACGGGATTTTTGATAAGATGGATTTTTTTCCGGCAAATTCGGCAACTCCGGTATGCCGGAATTTTCATTTTTGACAAATTGCTCCATTCGCCGAACAATAATTATGCCAGAAATTTGAAAAACGACAAGTCGCCGTTTGCCGATTTGCCGAAATTTCAAATAACCGGCTATAATTTGCAGATTGCCGGAAAACTTTTACATATTCGGCTAAGTTACCGCTTTGTCGGATTTTTTAAACCGTTTTTTTCAAGATAGATTTTTTTTCCGGCAAATTTCCGGCAAGTTTCCGCATCGGTTTGCCGGAAATTTCAGAACCGGCAATTTTACATTCTGCGGATTTCTTGTTTGACAATCTCAATTATTAAGACATATCGAACAATTGAGCCGGATCCCGAGCCGCCATCAAGCCTTATTCGCCACAGCTAACTACTTTCCCAAAATGTCGTATTAATCACTTCATCTGGAGACAAGACGAAGCTAGTATTGTATCGGATGTCCTGCTGATAAGGATTTGCGCATTTATGCGCTCGCTTCTATTCGGAATACAAAGTGGTATGATGTGGGGGAGTTTTTTTAATTGTTCCTATACACATATTTTAAATTACTTTATCATTGGAAAATCTAAATTATAGCCCAGTTTACAAAAAAATCTATATTCCAAAAAAAAAATTGAACAAAATCGATAATATTCCCAAAAAACGTTTACATAATCGAACTTTTTAAAACACTTTGAATAAATCGATAAGTTTACAACTGCTGACAATTAAAAAAAATCGAAAATTTCTCAAAGCTCCAGTTGAAAAAATTAATATTTTTCCCGAAAAAATTGAAAAAAATGGATAATTTCCAAGGAACATAAAAGCTAAAGATTTTTTAAAAAAATCGAAAACAATTCAAACCTTTCGGTTCACAAAAATTTGAAAAAAATCGTGATTTTTTTAACTTTTTTTCATCAAAAATTTGTCAAGAATTTGGAAAAAATAGAAAAAATCAATATTTTTCCGAAAAAATTTGAAAAAAAAATCGATAATTTCAAATAATAGTTGCAATTTATAATTTAACAGCGTAGACAAATTTTCAAAGATGTTTAAAATTTTTCACGTTTTTCTCTCTGGTTTTTTTAAAAAGCGTAATTTTTACCGAATTTCTCATCAAATTACATGAATTTTTCTGAAAGAGCGAGAGAATTAAAATAATTCGAAAAACTCGAAACAATTTGTTACCAGATCTAGCCGAAAAATCCCACAGAAACCACCAAACTTTACTTTTTTTATTTAATAAAAAAAAGTTTTAAAAAATATCAATCTCCCTTTTTTTCTGCCAAAAGCGACTTTGATGTGGGTAAGCTTGAAAAGTTTAAAAATTTGCAGGAAAAAATCAGGAAAACTCTTTGTATTTTCAGAGTCACTGCCAATACTCTCGTGCCTATCAGTTAATCGAATGCTCCGAGATTTGCGAAATAAATATCCTGAAGTTGCGTGTCTTGATGATTATGTAAGTTTGAGAGTTTGGAAAAATATTCGAAATTTTTTGGGAAAAATTTGGTAAAAGTTCACAAATGTACTGTACAATTCATTAATTTTTTTGCGAAAAAATTTTTTAAAATTCTCTATATTTTTGCTAAATAGTTTACAAATCTAAATAGTATGAAAAAATATTTTAGCAGAATCAACAAAAATTGTATAAATTCATAATTTTTTGAAAATGAAATAAATGTTTTTTTGCGAACCACTAAGACCAAACTTAAATATGCTAAATAGGTTTTTTTAATGCAGGATATAGTTTTTTAGCTGAAAACGTCTAATGAGAAAAAACGGATAACATTGAAAATTTACGTACATTTTTGCAGACCTTTTTTGCTCACAATTTTGTAAAAACTTTCGGCAAAAATATCACCTTAGTCAAAAAAAAATTGCTTAAAAAAAATTTCTATAATACAAAAAAAATGTGAAATCTATCTATTTTTTTCAAAAAATGAGCTACCTAAAAATCTATTAATGATTCTGTGCGATTTTTTTGTGAAAAATTTTGAAAAAATTCAGAATAATGTATAATTCCGTTATATAATATTTGGCGAAAAAAATTAATTTTTGAACTATAATTTTTTTTATGAAAACTAGTTTCAAAAATCGATATTTCACCTAAAACGAACAACCCTAAAAATAGGCGGCACACGAACTATGTTTCCGGCAAAGTGGTAATTGCCGAAATTTTTGGCAAACTGTATAGGCTTTGCAGAATTTTTTTGTTGGAAATTTCAGATTTTCAAATTTAATCGGCAATGAAAACGAAACGTTTATTCCGCACATCGGCAAACCAGCAAATTGCCGAATATAATATTATGTCTCCTAATAAGTTCCGGGGCAAAAATCATAACCTTGTTCGCTGTGTATCGATTTTTATGAAACTTTGGGAGTTTATGTTATCAACCGTGATCTTTCAATTGACAATATTCACACAGTTTTGTGACCACCCCAAGTGCCCGTACTCGGAGCCAATTGTTTCAGGTATTTTTCTGATCTCGCTTCTTTTTATCTTTGAATCGAGGTTTGTTGCGGATTTTGCTTTGTTTCGAATACATCGTTAGAAAACGAGAAAAGTTTGGAAAAAAATTTGTCCAATAAATTTTTTTTGGATGATCGGCAAAGAAGTTTCAAAAAGATTTTTGTCGAAAATTCTCTTTCATACAATGTAAATGAGGTGTCCGAACCAAGTGTAAATTATTTTTATACATACGAACAACATATCAATTTAGTTCGATACACTAAAATGATAATAATATAATTTTTTCGGATAATTTTTGAGTTTTTTGAATACTTCTTAAGTTTCAAATCGATGTTCAAACTAAAAGAATTTTTGTGTGTAAAAATAATTTTCACTTGGTTACATCATTTTTGTATCAAAAATCTGTGAGCATTTTAAAAATCTTTTTGAAGCTTTTTTGAAACCAAAAAAAATTTTTGGACGGATTTTTTTCCAAACTTTTCTTGTTTTCTAGTGATGTATTCTAAACAAAGCAAAATCCGCACACAAACCGATCAATATCTTCAAAGATAAAAAGAAGCGAGATCAGAAAACCTGCCCAACAAATTGGCTCCGAGTACGTTGGGGTGGTCAAAACATTTTGTGACTATTTTCAAAACACTGAAAGATCATGGTTGAAAACATAGATTCCCAATTTCATAAAAATCGATTTGCAGCGAAGTTAGGATTTCTTGACCCGGAAACTTATTTGGAGACCTTATACAATTTTTCAACATTTTCCAGTAAATTAGGGAGGTAATCGTCTCGAACATTATCGATTCATCTCCAATGTCACTTTATCCGATGCGTTTAAGCGAATTGTCGAAGCTTCACTTGCAATATGTGTATTCTGGTAGGGGGGTTAACTTTTTTTTTCCGGAAATATATTGAAAAATGAGCATATAAAAAGTTTTAAAATAATTTAAATATTTACAAAAAAATTTTTTCTGAAGTCAATTATATTGCGTTTGGAAAATTGATTCTTGTTTCGAGAACGGAAACTCTTTTTTTTTAATTAAAATGTTGAAAAAAAATCCAGGAAAAATGCTGAATTTTTCGGGATTTTTCTGAGCACATTTCTAGCCAAGCTCTAAAAATGAAAAACTTGAATTTTTCTTTATTTGAATTTTGCCCAAAAATGACTATTTGAGGAAAAAAAAAACATATTTCAATCACCGAAAAAATGTATTAATTTAATATTTTAATGTTAAAAAGGTATTTGAATTTTTTTTATACGACCTTTTTTTTGCACAAAAAGTTGAAATTTGGTTGAACCCGGATAAAATTTAGAAAAATTAAAATTTCAATTTTTTTTTGCGTTAAAAGTTTTTTAAGGTTAAATATGTTAAATAAGCACATTTCTTGAAAAGTTCTTTTGATTTTTTATATTAAAAAGTCTATTTTTCAAAAAAAAATTTATTTTAATTTTAAAATTTTAAAAACTTTAGAGTGGTGTAGTCGATTTTTTAAATTGTTCGATTAGACTCAGAATTGACTGAAAACACCGAATTTCATAATGAATCTTCTTGAATACTTCGCAAAAAAAAGATATGACTGCTAAAAAATGGCCTAAAGTTAGTTAAAATTTGAAATTTGATCGACTTGTCAAGCGGCTGGAAACTATTCTTTTTTTTGAAACCGTCAGATTTTGAGTATAAAATGTAATTATATTGGCGATATCAACTTTTTAGGTATTTTAAAGTCGATGGACGGAGAGAAGACATTTTTAAAGGTGGAGTACCGATATTTAATACTTTGCTTTTTTAGACCCAAAATGGCCCAAAACTACCGAATCTGCCGTAATGAGCAACGTTCTGAAAATTTTCCACCAAAAAAAAGTTATGGCCGATCAAAGTGCTTCTTTGGAAAAAACGCCATTTTTAGCTAAGATGTCAAACTTTGGCAAATTTGACAGTCTCGCACCGATAAGTTCGGCCAAAATTTCGGTCTAAAAAAGCAAAGTCTTATATTTCGGTATTCCACCTTTAAAAGTATCGCCGTCCACCGACTTTAAAATACCTAAATCAAGTTGACGCAAGATGCCAATTACATTTTATACTCAAAATTTGACGGTGATTTCAAAAAAGAAAGCTAGTTCCAGCGGCTTGACAACCAAGGTCGGTCAAATTTCAATTTCCGCTAATTATGAGGCCTTTGTCTTATTGGAGCAATCATAACTAGTTTTTTTGAGTGGTAACTTTTTTTTTTCGAGAAGTTATTGTCATGAAATTCGGTGTTTTCAGAAAATTTTGAGCTAATAAAGCAATCAAAAAATATTCGACTAACTTTTTGGCCTATTTTTTTGGGCTAAAATTGAAAGGTATTTTTCCAGCAAAAGCGGTCCGTGTCAGACGTCTGTCCGAACGTTCTCGATGCTTTAACCGACGAGCAGAAGCATTCGTTGACCGCCCTGGCACAGAATTTTGTTCTGCAAATTGCATTAAATCATATACACGAGGTATGCGGGGATTTGAGCAGAAAAAATGTTTAGTCAATTAAGAAAAAACCTTGAGTTTTTAAAAAAATCTGTGGATGAGAAATTTTCGCAATAAAAAAATTATATCGGTATAAAATTAATTTCAAATTTGAAAAAATTTCAATCAAATAAATTTTGAATTTGCATTCCAACGTCATCGGTCTAAAGAAAAAATTGCTTGAAAAATTGAATTAAATATATTTCTTTAACTACCTGTAAATTTTTTATTTGGGATCCGAGAATTCGACACTGAAATTTCATTTAAAAAAAATTAAATAAAATTTGAAATTTTTTGGAATATTGCAAAAAATTGCTAAAAATTGAATTTTCCTATATTTCGATCGGTTTTTTTTTAGATTTTTTAAAAAATTTTTTTTTCAGCCATTTCGGGTGGCCGAAAATGGAGAAAAAATAGTCAGAAAATTCAAAAAATTGCTTTTTTTTTTCAATTTTCCGAAATTTTGTATCTTGATCGTCCAAAAATTTAAAAAATAATCGCTAAAAAGTTTAAAAAAAAATTATTGAAAACAATTTTTTTAGCCAAATAATTTCTAGTAGATTGCATGAAAAAAGGCCCTAGTGAAATACGAAACAATTTTTTTTTCAAATCCGATTCAGAAAAAATTGAATTCTCTCTGATTTTGGGCCGATATTTATAAGATTTACAATATTCCAAAAATTCTTGAGAAAAATTGAACTATGTCTGCCGTATTCCTGTGAACATAGCGGAAAATTGAATTTTCCAGGTTATGTTTATCGGAAAAAGTATAGTGACTCTACGTAGAATTCATGAAAAATTCTGACAAAAAACCAAACATTTTGGCCCAAAATCAGAGATTTCACAAAAAAAAATGCTGAAAAATCAATTTTCAGCAATTTTTTTTTCAAATTTTTTTAAAAAATATATTTTAGTTAATTTAATAATTTTTTTTTCCGTTTTTTTAATAGAAGAAAAGTTATTTTCCCAAAAATGTGCAGACATTTCAGAATTTTCGGAAATTAAAAAAATTTATTTAGCAAAAAAAAAAATTTTTTAATCCAATTTTATACTATGATTTTTTCACTTTTTCGGTGGTATTAGGACTGAATTCAAAGTCTCTTCGAAAAACATAAATTTTCAGAAAACTTAAAATTAATCTGATTATAATTCGGAGCATATATGAAATGTGCTTTTATCACAACATTTTTTTTTTTGACAAGTCAAATCTTTCCACATTTTTAAAAGTTCCTATTTTGTATATATTCGGATTTAAATTATTTTTTTAACGGGTTTATTGTCTGAGCAAAAAAATTGAATTTTTCTAAAATCACCAATTTTCTTCCAGATTCTCGGAATCGATCGTCTTCAAGACCCACTATTGATCTACCATAGGATGCTCCGATCAAAGACCACTGGAGAGCAATGAAAAATGCTGAAAACGCAGAAAATCTCGACGATTCGCCAGTTTCCAAAAAGGAGAAGGATACTCGACGAGGAGCCCGCCGATATTTGAGGATTTTTATTTTAAATTTGGTCGGTTTACGAAATTATTTAATTTTCCTCTATTCTCCCTCATCTCTGTGTTTTTTTCTAATGTCTTTGGGCGTAGAAAAAACGAATGGCTCTCTTCGCGGTTAAACCTTGAAATTTTTATTTTTCTACTATTACCTCCCCCTGCAAACGCGCTCTATTGGCGACAATTCGCAATGGAGCGATTGCATATTTTGTTACCATTTTCCAGACATACTCATGTTCGATCTTCCACTAGGGGAGGGTCTCGCGATTTTTTGAAAACTAAATTTAGATTTTTTTTTGAAAAATATTCGAAACAATTTTAGGTTTTTCGAAAAATCCTAATTTAGCCTAAAAAATCAAAAATTGATGGGATTTTTAAAAAAAATTCAAAACTTATAATCAAAAAAAATTGCAAAGATGTTTAATTTTTTTGTTGAAGAAAATTTTTTGTAAAAATTAATTGATTTTCCGCTTTGAAATAGTTTGAATTTAGAATTTTTTGAAAAATTATAAAAATTTTGAATTGAGCTTTTGAAAAAACATTACTCAAAATTGTTGGAAAAATTTTGAATTTTTTTGAATGAATTCAGAACTTTTTGAAAACGGAAATTCGAATTTTTCTGAAAAAAACGTTCGCAAAATTTTTCGAAATAATTGAATATTGAAAAAATTATAAGTAAATTCCTAATTTAGTCGGAAAAAAATATTGAAAATAAAGTGACGATTTTTGAAAAATTTTCCCAAAAATTCTATAGAACTGTCCTGAATTTCTATAAAAAATTCGAAAAAATAAAGTTTTTTAGAAATTTGCAAATTTCTTTAACATATTGGAAAAAATTCTATTTATTTTTGAAAAGTCATTTCTAAAATCTTCCTTTCTGCTAAAACCTGCAAATAAAAGGACCCTGCCCCTAACTATCTTGTTCATCCAAAAACCGACAATTCTTCTGTTTTTGTGTTATAATCGTCCTTTTTGACTTGTCAAACAAAAATTAAAATAAATTAGAAGAAAAGGGTTTAGATACGATTTTGCCAGCACGAGGCCGAGGTTTTTCACGGCCACGTGGCACAGGCCGGCAAGTAAGGCTGAGGCTGTGGGGGGAAATTGATAGGGAAGAAGGCAGGAAAAAAAAAAGAAAAATTCAATATTTTAAAGCCAAAATAAATTTTTCTGAAAAGACTAGCAAAACAGGAATGGTTAGGGGTAAAGCCGATGTCGGAGTTTGACGGAGAATTTTGCAAAAACATTAACAAAAACGAATCGGTAGGGACGGACCGGCAAGATTGATTGTTGAAAATTGACGAAATCTATCGATTTTTTGGCGCACGGGGTTCTGGCCTTCCCTCATAAATGGAAGAGTTTTGCCGAACTGGGCCACCAGGTCATAACTGGGGTAGGTTTACGGCGCGTTGCGTGTCGCGTCGAGGCTCAATTTTAGTTGTAAAACTAAAGAAGATGTATTTGTCCGTGTGAAGTACACGACTTTCCCGGGGCGCGATTGTCATGGAGCGCGAAAAATTAAGGGCCAGACACAGAACCCCGTGAAAAAAGATAATCCCGTTTAGAATCGGTGAGGGCGTGGAAAGAAAAGATGATCAAGAAAACGGGAATGAGCAACATTTCCAAAAAATCAACAATAGCGCAATTCCAGAAAATTCCATAGAAAACGGGGTCTAAAGCACCAGATTAGTGTTGTGCGTGGGCGTCCACTGTGACGTCATCACCGTCCACGTTTCGTAGTTCTACCGACTCGTGCTGATCTGAGAGCTCGGCCGAGACTTGGAGATCTCGGTGAATGTGGCGAATGCTTCGCGGGTGAACATGTCTGGAAAATCAGCAAGTCAGGAGAAAATTCAATTTTGCGCGTCAACTTTGATGTTTTGTTTGTGTTAGTGAACTTCAGAAAATTGAATTCGCCAAATTTTACGAGCAAAAAATTGGATTCTTTTGGTATTTTTCATGGAAATTTAACCAGGTTAAAAATCGAGGTTTCTCCGGAAATTTAACGTACTTTATCGATTTTTCATCAGAAATCAGTAGAAAATTCCTTCTGCGCGTCAATTGATGTAACCTTCGGGCCGTGCGGAACTGAACTGGATTTCGCCTAATACGAGCAAAAGGGGGGCTACCGTTTGCAAATTTTTCTTGGAAACTGTCAAATATTGAATTTTTCGTGAAGGGCAAAATTTAACCAAAAATCGGGCTTGCTACGGGATTTAACAAATTTTATCGAATTTTTTTGCGCGTCAAATTTGATGTTTTTTGTTGAACTTCGGAAAACTGTATTCGCCAAATCTTACGAGCACAATTGGACTTTTTGGGTATTTTTAGTCCGAAATTGATTGTCTTAGAGATTAAACGCGATTTATCCATTTTTTATCGGGAACAGTAGCAAAATTCAGTTTTGCGCGTCAAATTTGATGATGTTTTTTGTGTTGGTGAACCTCAAAAAACCGTATTCGCCAAATCTTGCGAGCAAAATTGTATTTTTTGCGTCTTTTTCGTGGATTACAAAAATCGTGCATATCTTTTAAAAAAAAAATTCCACACAAAAGTACATTTTCACACAAAAACTGCAATTTGCGCGTAAAATATGGCGCAACCATCGGTTGAGTGCGGCACGCCGACTCAAAAACACCATATTTTTCACGCGCATATATTAATTGAAGCGCCTTCACGTGGTGTCAGGATGGGTCCACGGTTTGATCTACAAAAAAATGGGGGAATTTTTTGCCCAATAATATAGGTGACGTGCATGTTCTTAGCCATGCAGAATCAGTCTAAAATCCCGCCTTTTTTGTAGAAACGTAGATCAAGCCGAAATGAGACGACTCTGGGCTTTAAAACACTCACCAATAAAACCGAGACATGATCGGAACGTTACACGTGCACTTCCGATCGAATATCTCCATCGTCACACCGGCAGCCCTTTCTCTTTTTCTTCTCGAGTCTGGAAAATAATGATTTTAATTTTATTCTTGGAATTTTAAATTTCAAACAGTAAAAAACCAAAAATTATAGCAGTATTAACTTATCCAAGTTAAAGAACTACAGTGAAACTACAGAAATATTAATAAATATTTCGATGCACCAAGAGCCGAAATCTCTGAGAGCCCAAATCTCGGCTCATTTCGAGTTACATTACAAATAAACTGCAAGCTATATATAGAAAATTCAATTTCAATTATTTTGTTAGTTAACAGAATTTGGCTAGAATTGAAATCGAGCTGGGATATGGGCTGGCTAAGTGAATTTTTCCTTTTTTTTTTTGTTTATTTTGATATCCAGGGGTGAGCAGCAAACGATGTTTCCGGCAGATCGGTCGCTAGCTTGCCGGAATAGAACACTGCAAATCGGCAAACCGGCAAATTACCAGACGAGTTTGCCGGCAACGTATGCTCCCTATGAGCCACCCATCAATCGATTTTGTCGGCTTATATTTACGCCATATGGCGGTTTCAGAAGTTTTTATTTTCATGAAAACCAGAGTAACTATAGATCATTGAAAGAATATTTTGTCGTTTATTTTGAAAATATGATAAAAGACAACCGAGATATAAACGGTCAAAGACTAGTCAAGGGGGGCCATACAAAAATGTTTTTTTGTAAATTTAGAAGAAAATGTGTTTCCGTCTTATTAAAAAAATCTCTCTAAGCATTTCCGGCAAACCGGCAATTGCCGCCCTCCCCCGACCTACGCACCTGTTCAAAGTACTCCTCAACAATCCGATGCGCAAACCCCATCGCTCAGACACAATCCCTCTCTCGCCGGATTGGAGATGTCGGGGCGCACTTGACAAGCATACTGCTCATATCGGAAGTGAATTCGTGTCACGTTGCTCCTCCGGCACATCTGTCACATGCATCTTGTTGAACTTGGCGAGGTACTCAAAGTGTCGACTGAGGTCCGTAGCCAACACCATCTCCACCATCGCATATCGCATTTGTATGACTCGCGCGACAGACTCGGGAAGATGTTCACGTTGGCGTTGTGCTGAAGGGTGCTTAGCTGAATGGTTAGCCTAGTGCGGATAATTCCAGGAGTTATCATTGTAAAGTATTGCAAGCTGTCGCGTCGTATTGATCAGGTACGCGTTTCCTCTTCCAGGATGGGCTAGATCATGCACCGCCTCTGCGAAAAGAACCGCCGTCACCGCATGACTTTCATTCAAGTGCACGGAGAACGACGGGGAGTCAAGGTGGCCTGTAGGACGTCGGCTGTGTGAGTTGCGTTGGGATACGTGTTTCCCGCATGGTAATGAGCCTCGATGGATAGATTAGAATCCAGCGGTGGAGGAGATCGTCGGAGCAGCCGAGCACATCGCAAACCTTCCACCTCTCGAAGACTTTCATTCCGATTTCCTTGGGAAAGAGCGTCGTGATCCGACACCTTTTCCAGATGGAGGATGTCGAATTTCCAGCAATTGTCGTTTTCCAGCGGGTGAGGGTCTTCACGTCAGCGGATACCCGTCGACATTCTGCATGGGATCCTCGCTTCTCTCGATGCGCGTCGACGACGCTTGCGCTGCCTAGCTGGATGATGGAGGCGAATGAGACAATCGTAATATTGAGTTGCCTATCCGATCGGCGTCGCGGAATCGGTTGATCGACGGTGCGTACAGCTGGTCCGACGACAGCACCTTCATCGCGTCCTTTATCGTTTTTGCCGGTTCTCCGTCGACCCGCGACACGTCTCGGAGCATTGTGAGCACCTCGGAGATGGGCGCCTAACGATGCCGCCAGTCCGCGATTTCAGGCTTTTCAGGGCGCCGTCGCGGATTGGCGGTACCGGGTTGGTGTTCTTGTGAGCGTTTCACACGAAGTGACTACTGCTAAATAGAATTTTTTGATTAATTGGTGGCCGAGCTTTTTAAATGGTTGCCGCGATGTTTAAGTTGATGGCAGAGTTTTATAGGTTGATGGCCTAGTTTTTTAAATCGTGAGTTTCTATGCAATTTTGTGGCCGTGTTATTGTATAAGTTGGTGGCGGAATTTTATAAATTGACGGCCGAGTTTTGTAGGTTGGCGGTCGAGTTGTATGAATTGGTGGACGGCCTAGTTTTACAATTGTGTGGCCGAGTTTTTGTATAAGATGTCTCGTGATGAGCCGAGTTTTTTCAAAATGATGGCCGCGATCTTAATGATGGTCGAGTTTTATAAGTGCCGAGTTTTATAGGTTGATGGCCGAGTTTTTATGTAATTTGGTGGCCGAGTTTCACAAGCTGATGGTCGAGGTTTATGAATTGGTGGCCGTGTTGCTATACAATTTTGTCTGGCGGTGTTTTTATATAAGTATTTGGTGGACGAGTTTTATAAATTGGTGGCCGAGTTTAACGGAATAAGCAAAGGAAACTAAAGCGAAAGTGCTAATTTTATTGAAGGGTTTTAAAAACTGGGCCATCACCTTTTCAAGAAAAACTCGGCCTCCAAATTTTCCAGCAAAATACTAGGTCGCCAGTTTTTCCAGCAAAAAAACTCGGCCACCAAAATTTCCAGCAAAAAAAACTGGGCCACCAAATTTTACAGCAAAAAAAAAATCGGCCACCAATTTTTCCACAGAAAACGGGCTAGTTTCATTGTTCGTTTGAGAGAAAGGTAGGTCACGTACATTTTCAATACGAATACTCGGCGACCAATTCTTTATAAAAAATTCCGTCATCAATTGTCATAGAGATTAAGTTCGGCCATCAAGGTTGAAAAATAAACTAGGCCACCGATTTTTTTAGTTGAAAAAAACTGCTCGAACACCTAACCTTAAGATTTTCCTTTTTTCTAGCCTAGAGCACGGTTATCGCGTTTTTAGGCCACCGATGCATTTTTTTAATCGAAACTCGAAAAAAAATCGGTGGCCGACTTTTTATCATATACGGCCACCAATTAAAAAAAACTCACTTGTTAGCAAACGGGACCCGTATCATTTTCCTGTCTCAATACCCTCCGTCCGCTTGCCGCTCCTCTTCGGTGCAGGGCCCTCGGGTGTACAGAGACTTCCGTCGCATTTCCGATGCGGGTTGTCCGAACACCTCGGATTATGCATCCCGTCACGTTCTCTAGCCGTAGGCGCAAGGATAACGTACTGCACTAATCGTTGCTCATCACATATTTCCACTGCTTGATTCGTCTGAAAATATCACCGCAAAATTTGAAGGTTTTTAGGCACATGTGGCGCCAGTCCATTTTGATCTACAAAAAATGCGGGAATTTTTCACCCAAAAATATATGATCAGCTCACCCAGTTCTTAACGATTCTAAACTCACCCGCATTTTTTGCACGCTCTACGTAAATCAAGCCGAAATAAGAGACACTCTGACAGCGCGTGTAGGCAGGTAGGCGTTCACCGAGCCAGGCGATTAGGCCAGGAGGCAGTCGATTAGGCAGACTAGTAGGAGGTAGGCAAGTAGGCATTGAGGCAAGAGCTCACCTAATCCAAGACCGCGAAAAGGGCTATGGGCAGCGCGCGGATCCGACTCGCGAGCCGCCCGACGTAGTCGAAGAGCACCACAAGCGTATTCCACGTCACATGCTTAAAAGAAACGCATGAATGGGAATCAGTGTGTATGAAATATAAATTAGAATTGTAAATGAGAAACTGAGAAAACGGATGACTTACCATGATGAATGATGTTGGAGTGCGCAAGAGCTCTCCCTCGCTTTTCGCTGATGTGTCTATGTCGATTGTTAGATTGACAATTCTGGCAGAGTGGTTTTCTAGAAAATTGGGGAAAACTCGGCCAGATATGTTTTCTTTGGTTTTGGTTGGATAATTTTGGCGACCGAGTTTTTCAACGTATCCTTTATGTGTCCGTGGCCGAAGGCACATAGAAGAAAATTAGAACAATGCCGAGTTTTATCAACGTAGTCTAAATTAGGTGTGGCCGAACTTTTCGTCTGACGGCCACGCAGCAAGAGGAAAAAATAATGAAACAAAATTTGGTGGCCGAATTTTAAGCCAACACAAAAAGTTGGTGGCCAAATTTTAAGCCAACGAAAATTGGGGGCGGAGTTTTTGTTTTTTGAAAATTCGTGGCCGAGAATATGGGAAAACGCGGCCACACGATATTTTTTCTTTGGTTTCTGGCTGAATAATTTTGGTGGCCGAGTGTTTTTGTTTTGGATAGGGCAGTTGTGGTGGCCGATTTTTATCATTTAAACCAAATTTACGTGTACTTGGACTTTTTCTGACGGCCACAATAGCAAGCAAAAAATAACGAAAAGTTGGTGGCCGAATTTTAAATTCATAGCAAGAAAAGTTGGTCGAATTTTAAGCCTAAAAAAAGTGGCGGCGCTTTTTCTACAAAATTCATGGCTGTCATTATTTTAATTGGAAAAACTTGTGGCAGTGATTTTGTCTCGAAAAAAATCGTGGCCTTTAACTAGTAAAATTTGTGGCCGACTTTTATTCGCGTAACCTAATTAACGTGGCTGTCGCCGACTAAGGCCACCTTGCAAGAAGGAAAAATACCCAGGCGAAACAATTGTGGCCGAATTTTTAGTCGAAAAAAATGGCGGCCGAGTTTTTGTTTAAAAAACCGTATTTAGTTGGGACGAAAAATGGTGTCCGAGGTTTTTCAATGTATCCAAACTTATGTGGCCTGTTAGTGGCCTATAGCCTAGCTTTCCTAAACCATTTGTTTATAAAGTTGGTGGCCTAGTTTTTAACCAGCATAATCCAACTCACTCACTTCTCGGCGATCGACACAATCAACACCTCCGCTGTGCTCACCGAGGCTGAGACGTCTCTGAAAAAAAGTTTCGTTAGTAGATCATGGCTGACGACGCTGCTCCCTTACTTGGCGATTTATCGAGCGATGGATGAGGTACTCGAGATCTATGAATACAGCTAGAGGGCATATTGATTAAACGTCGGATAGTGCAAGCAAGTGTACATAAAATTTCCGAAATTCAATTTCCTTTTTCCCTCGCCGCGCCACCGTGTCCGAATTTCGGAACTGACCACGTTTCAGTCGTCTTGGTAATTCCCAATTTCCTTTCTCCCTTTTTACGTCACATGATAGCGGTTATACGTGTTTCGATGCATACACAACAAGGCACTTAATCAGCTACTAGCTCCTCTCCCAACCTCCACAGAGAGACTGTATGAGCAAGAGAAAAAGCACCTGCTTCTTCCAGATTAGGCGTGAGCGAGCCTGTTGTCATCTGACTTCTGCTGACGGAGGGAGCTTGAAAAGCGGAGCAGGAAGAGGAGAAGAAATAAAGAGCATTCAGAAATTACGCGCGAGTCGTAGTAGCTATTTATACACTGACTTCGTCTCCTTCTTCTTCCTGCTTTTTCCCCGTCTGCTCCTTCGCTCGTTGATGTCTGCCATCATATTTCATTAACGAGGGCCTAAGAATCCTGGAAGAGTGACGTCACACTGATGGCCTCTACTAGGAATCTCAAAGGCAGGCCATATTGATTCATATAGCAGGCCATATCAGGCCCCATAGCCTGGCCATAGTAGGTCACCACAAGCTATGGACTGCCATCAGGATTTTGGCTCTTTGGATGATAAGCTTCTTTGGAGCCCAGCGCTTAACAGACTGACGTCGTGGTATCGAGAATCTCGGCTAGGCAGAAACGCGGCAATTGTGAATTTTTTGACGCACTAAAGATCTTATAGATCCTTGAAATCTTCCACAGGACTTAGCAGACCGGAGGCCTGGGAACTATGCAGTTAGAGGCGCCAAGTCCAATAGTGGGCTCCGAAGAGAGAGTGCCCAGAAGGGCTCCGAAAAAAGCGTAGATTTTGGGCCAAAATTTCCCAAATTGGGCCAAAATTTCAAAAGTAGTAGGTTTCAACCCTCATGTTTCCCGGAATGATTTTGTGGACTATTATTTACAGACTGTGGTGGCCTGCTACCCACAATATGTACTGGGCCAACCTCTGGCCAGGTTACGGCCTTTAATAGCGAATTGCTCTTCCCTTGGAGTCAAAGTTCTTGCAGAGCCTAGGAGACGCTTACCACTTTGGATCAAATGATCTAAAACTCAATGGATCATGACCCTAGAACCTCAATTTGACCCCTAATAAGCCTAATACGGAGCTACGTCTAAGCTCCCAGGCTATATGGCCTGATATGGCCTGAGCAACACTTCGGTGTGGCCCAGTCTAGGTTTTTCCAAGCCCCAGCGGGCCTCAGTTTTTATAAGCCTAAAGACGCAGCTACTGGGCCAAGCTCTGGCCTTGAATTTTGGAGTAATTATTGCAGAGCCATCATGCCTAGGAGGCCTAATCTAGATTTTTTCAAGGATTGAGGCCCCCACGAGGCCTCAATTTTCATAAGCCTAAAAACTCAGCTGCAGCCCTGCCTGTGTTGGAAACTGTACAAATCCTTATATGCCCGTAACGAGTCAAGAGGAGTACACTCTCGCCGGTGCCTTCCGTCACGATCACAGTCTGAAAAAGACGCATTATTTATAAGATCTTACAGGGGATTTTCAGATTAGGAGGGTCGTGTGCCAGACCTCAACAGCTCGCCGGGGGTGATAAAATGCTGATTGACTTGACATGCATATATATAGATATATATGAAGTTGGAAGAGCGGAAGCAGCAGCAGTGGCAGCAGAACTTGTGTGTGACGGGGATTTGTGGGAACAAGGCGCCAAAGAAGACGAAGCAGAAAAGCAGAAGCCAATGGGGGCAAGCAATGAATGCAATCTATGTAGGAGTATGTAGGAATATGTGTGTGTGTGTGTGTGTGTGCGAAAGTCTCTCTATCTGTGTGTGTGTGTGTCACAGGTTATATCGTGTGCACAAAAAATGTATAAGGTCTCCTGATGTGTGTGCGAGTCTGTGAGTCTGTGAGTGCAGTGTACAACACCTTTTGCGGAGTCTTACCACATACTGATACGAAAGTGTTTGTATTTTATATATTTCTTTGCCACGGCACACTCTTCAATTTTTCGCGGGCTCGCCCTGGCCCATCAGTGGCACGCAGTAGAAAAAGTAGTAGAATAACATGCGTTGTGGCCATAGCCCATCCAACTTTGTTACTTACGGACTGAATTCGCGCGCGCCGCGGGGAGGAGAAGCAGAAGACGACGACGACGAGCTCGAAAGAAGACGAGTTGCGCCTCTGCAGTGCGAGTCCCTCGGCAGCGGCACTGCTGCGCCGCGCGCTTCGATGACGCGAGCTCCCCCCCCCGGCGGGAAAGTACGCGATTTGTCACCGAGATGAGCGCTTTGCTGACAGAATAGAATGGGAAACACAGGAATATCGGATTGCAGTAGACATGTTTTGTTGCAAAGTTATGAAAGCTGGCTTGGCGTGGTCGTCGAATTTTTCGCGCTTCATTGACGGGAGAGAAGGGGAAAGTCGTGTTCTCCACTTCACGGAGAATCACACTAAGATTTAGGACTAAAATCGAGCCGAGCCAAAATGGCCTAGTTCTCGGCAGAAACTGTTCCATTTCAATCTGCGAGGAAAGCCAGAGTTCCGTGAACCTCGGCCCTGCGATCGCCGGCCTGCGATCTCCTAGACAAATGGTCACCCCAGCCGGGACTCGGGAAAGTTAGTGCCAGGAGAATAATTTTTGAATTTGAACAAAAAGAGGAACTTGTACAGTTTTACAGCATCTTCAATTGCATCGGCCCAAACGTGTTTGTGGAGCTGCTCGTTGGACAGTTAGCAAAGGTAGGGTTGGTGGAGCACCACGCGATCCACCTGCACCACCACCATTCTCAGGAATACGACCCACCGCAGCACCATCTCATTGCTAACACTGCCCTGGATGCTGCTGCTGCTGTTGCTGCTGGTGCTCTCTGTGCGTCTTTTAGCTGCGGGCGTGTGCTGCTGCCTCCTGCCAGCTTGACTGTGCTAGCCCCACACTCTTGTCACCCTCTTCTCAGCCCCCCACCCCGCTTCTATCGCCCATTCTCTCCACGAATTCTTCTGTCTGACCTCCTCCTCCTCCTCCTCCTCCTCCCAATTCTCATGTCATCGGGGGGCCCGTCGTTTCGTGGAGCGCCGCGCCTGCAATGTCTCGGGCCGCCGCCGTCGTCGTCGGCATCGGGTATCGTGGCCCGTCGTCTTCGGGGGGTGGGTTGTCATCTGCTGTGTTCACAGATGCCGCCGCCTTCACCGCCCATCTCATCGTCTCCTCCTCTCTGTGGACCCGCCGACCGCTTAAGCCCGCGCGCCTTCTCCCATCAGTTCTATCTCTCTCTATCACTCTCTTATCTCAAACCGCGTCAATTTATCTCTCTGGCAGTACTCGCTCTTCGCTCGGCGAGCTGTATTGGGTGTCGGTTTTCAGTCTGCGTCTCCGCGCCCCGGTGCAATGCATATGTTCCATCACGTTCTGCTCCTCCATAACAGGTTGCTCCGTGTGCTTCCGTGTTTTACGCAATTTGAGGTAAAATTGATACAATACAATTGATAATTATCGAAGTGTCCTCTATGTGTACTGACGCTGTTAATTTAATGGCCTAACCACAGAACTATGCTTCTTTAATTTTTGAACTTCTGTCGTAGCTCCGTAGTTAAATCCACTATGAGATTCCTTGCCATACTCGTTTTTGCAATATTTTTTGAGGTTGTTTGTTATGGAGAAAGTTTATGTGTTCTTTGCTTCTTTGGTTATATGGGAACCCAGCTGGCCAGAAGAATGGAAGGTTTTCTGGGACAGAGCTTTTGAATAGCCCACAATAGGGCCCCAGTGCCGGTAGGCAGGCCCCGAGGCCCCTAATTTAGTGCAGATAGTCCTTATTCAGCGTATAGATGATTCAAAGCTAAAATCAAAGGGCTGTTCCATTACGTTGTGATCTACAAAACATGCGGAATTTTTCGCCCTAAAAATGTGACGTCATCACGTTCCATGCGTTATTATTTATGAAGCTACCTCTGCGTCTCATTATCCCGCTTGAAGATCTAACGTAGATCAACCAAGCGCCTTACCCCTAGCCTCTAAGCTCACTACCTAGGGCCCTCTAGGACCTTATTTCGGCTTTTTGGACTGGCCAAGACCTCGCAATTGGGCTTTTAGGCTCCTAGGTCCCTCAAGGACCGTTAGTCTTGGACTATCTGAAACGATCTGCGTCTAGGCTCCTAGGGCCCTATAGGACTATTTAGGCCTCTTGGACTAGCTGACCATCTAGATCCTTCTAGGCCTCTAGGGCTCTCTAGGACCATGTTCACTTGTCTATAGGACCTGACTAGCTAAGACGGGCTTCTAGGCTTCTAGTAAGGGCGCTCCAGGACCTTAGCCCTCTGGACTCTCTAAGACTAATTGGGCTTCGAAGCTCCTAGAACCCTCTAGGCCCATTTAGGCCTCCTGGACGATCAAAGATCTTCTGGGCTTCTTCTAGGCCCCCAATTTCTAGGACCTTCTAAGACACCCAGTCTTTATATTCCCTAGCGTCTAGGCTCTAAGATAGGCCTCGTTTCCGCAATTCCTACTAATGGCTTTGGGAGACCACGTCACTTTCTAAGGCCCATGGACTTCCACAGTAGCTTTTCACGACAGCCATTTCCAAGTTAACGCACTCAAGGACCATTTAAGCCTTTTGGGCTATTTAAGACCCCAGATCTGGGCGATGACTCTTTTTTCTAGGCCTTTTGCCCTCTTGGGCGCTCCTGTACCTTCTAAGACCCTGGCCTTTTATCCCTAGCCTCTAATCCTCTAGGACTCGATTCCGTAAATACATTCCCAGTCCTAGACGCTCTCAGGGCCCCTGGGGTAGCCTTTCGGTTGACCATTTCAAACAGGCCGTTCCGCTCCATCTCTCCTTGCTCTCTCGTGCTCCTTTCCTCCACCATGTTCTCTCATTGTTCTGACGGATGGTGATGAGCATCATCATCCTCAAAGCTCCAAAGACAATTGCCATCAATGTGCCGCCGCTGTGATAAGTGGTGTTATTTCGCCGGGACAAAAAAAAAGGGAAAATTCTCCATGGGAATTTGCGACTAACACCTCCTATTACTGTAAAAAAACATCTGGAGAAGGGGGAAACGAACTAAAAAAAAACAAAATAAAATCGGCGTATCAAATTGAAGCTTCATCATATGATTCGTCGCCGTCGTCTGCTCTGTTCGGCAATGATCGTTTGTTCGCGTCGTCAAACTAACCTACTCAATGTCATAAAGAACAGAGAATGAATTCAATAAAACATGACGAAAAAATAAATACATTCAGGTACTGTAGCTAAATCAGGATCACATCTGGAATCGCTCTCAGCCTGTTCGTTTGTGGGAGCTTGTTGAGTATAGGCCGACCACTACGCCGCCGTCGACAATCCACGACGACATATACCGCCACCGACGACTACGTATGTCCCCTGAACTTTAAAGTTGCATTTTTTTTTAAAGGATTAGGGGTCTTTCGAAATAAATTTCAGTTTTGGTAATTTTTTAAATTTAGTTTTATTTTTTTACGGGCTTTTGCGATTATTACTGCTAGAATGAAAGTATGTACATTTCTTGTAGATCAGCAACTTTAATTTCTGATAACCGATAAATGTTCCGAAAAACTCGAAAAAAAAATAAATTTTTCCAAACTAACTAAAAAGTAAATTTATTTGTACAATTCAAAGTTTGTAATTTTTGACAAAATACATTCAGAAATCTTTTTGGAATAGGGGTTAATTAGGCTTGGGCCTAGGTTTGCGCTTGGGCTTGGGGTCAGGCTTAGGCTTATGGCTAGGCTTAGGCTAAGGATTGGGCTTAGCTGGCTTAGTGCGCTGAGGCTTGGGCTGGGGCTTAGGCTTCAACTTAGGCTCAGGCTGAGGCTTGTGCTGAGGCTTGGGCTTAGGCTTAGACTCTCAGGATTAGGCTTGGGCCTGGGCTTGGGCATGGACTTAAAAATGTTTTGTTTTTCAACAATTTGGTTGTTTTTCGAAACCTGATGGTTTTACCGGTATAAAGTGCCTTTTTTTGTACATAAAAATAATTTTTAAATTTTTTAACGTTCCTAAAAACTAAACAAACTGTAAAGAAAATTTTATTTAAAAAGCAATAAAACATATTCTTTTTCAGTAATTTCAAATTTGATTTCCCGGTCATAAAAAATCAATTTTTTATGCAGTCAGGGCCACAAAAAAAATTCGTTGAAAAAAATTCAATTGGATGTATTCTTCGTGCTTGCAAATTCGAGTCAATTTTCTAGGGATAAAATAGTTGTTTATTTTCCCTGATTTTTTGACGTTTTTTCCTTTTTTAAAGGATATTTTAGGACTTTCTGGGATTTAGAACGGTTTAGCCTAGGAGTGATTAAGACTAGGTTTAAGCCTGAACCTGATGGGCCTTACAAGCCTAAACCGAACCGCCTAAGCCTAAGCCTAAGCCTAACATCAAAAAAACCTGAGAATCCCCTAAATGGCGCAACGTCGAGTAGCAAGCTGATGCTCGCCACTGACACTAAGCCTAAGCCTCAGCCTATAACGAATAACAATTTTGGAACAAAAATTGCAAAATCTCCGCTTCTCCGCTTCTCTTAAGACATCGAATTTCCTAAAAATTTTTAGAAAAAAAAAATCCTCGGTCCAAACTGATCTGAAAATTCTATCATATTTAGGCTTTAACAAATTTCACTTTTTTCTGGGAGAGACACTTTCCATAACACCACAAATTCGGCGAGTCGACCTGTTGAGGATCTTGTCTCGACCCGCTCTCTCTCTAAGTGATTATAACAGAGATCCCACACCCACCCACCCACCGTCATCTATTATGTTCTAGAACTTTATACATTATGATCAAAACCGAATGCTACAAACTACAAAACATCGCCACTTTTTCCAAATTTTCGGCACATTTTTGCAGTCCGACCACAACTACAAGCACCAAATCCATGTGAATCATCGCATCCGTTGGATCTGACGCGTCGGCTTATAGACGGGACACTGTGCCGGCTACAATCTTCTCTATATGGCCAGCGACTTTCCCGTCGTCGGCTCGCAATGAGTTTCCTGATCTCAGGGGTTAGGCTCACATTCAACGGACTATGATCGGGAAGAGGTGCCTCAAACGATAAGTGAGCTCTCAATGCCTACCTGCCTACATGTTTGCAGTATCAAAGATATGATGCCTACAAGCCTACCCCCCTACCTTGTCCTACGAGCCTGAACTTACACATTTTCTGTGCCTAACATGCTCGCTATACTTTTGTCTGCCGTTACGCGCCCCCCCCCCCGCCTATCTGCCTCCAGAAGTCTCCATTTAGTCTTTATGCCTGCACGCCTATCACAGGCCTCCCATTTGCTTGCGGTCGAGTCGATTCATGCCTACGAGCCTGCGCCTTACTAGCCTGAATTCGCATTTTTCCAGTGCCTAGCATGAGTCCCTATGCCTGCATTTACGCGCCTTCTCCCCTAGCTGTCTACAATCGCACTTTCTGCCTACCTGCATGCTTTCCTACCTATTCGCAATACTTAGGCGTACCTAACACAAGCTTAGCGACTACAAAAGCCTTCCAGTGCCAACCAGCTGCATGACTGCGTAGCCTTTCGCCTGCTTAGGTGCCTACCATAATCCTCCCTTTTGTCGATATTTCTACGCGCCCATACCTACATTCCTATCTTGTTTGAATCGATACATATCATGCCTACGCACCTACCTTGGCCTACCTTGGGCCTACACTCCTGAAATTGCACTTTTCCTGTGCCTAGCTCGTACACTATACTTATGCCTGCCTTTAGGGCTTTCTCCGCGCTTATCTGCCTACAAGCATACCTTCTGCCTCCTTGCATGCCTTCTTATATTAGCCTGCTTACCCGAACCTACCACAAGCCTGGCTGCCCAAACTTCCCTTCTGCCTATATGCCTACGCAACTCCTGCCTGCCTATACGTCTACCTCATGCTGTAAACAGACCTGCCTTGTACCTACCTATGCGCCTAAAGATTGGCTGTCTCCTACGTCTGCCTGGCTGCCGGAATATTTTGCCTATAGGAATTACTGTCAGTGCGTCTTTACCCAGATCCTACCTTTAGGTAGACGTCCCCTAAAGCAACCGCCTGCAAGTCTATCACTTCGCCTCACGCCTCCTTGCCTACCTACACACCTCCCTTATCCCGGCTTTTCCACCTGCCTATGCCTATCGCATGCCTACCCTCAAGACCTGCAAACGTGCCTAGCCGTATGCCTACCTAACTTCGCGCCTACATATGCCTCCCTTTCAGATCGAGATTAAGTCGGAAAATAAAACCGGCCAAGGCAGTAGCCTCCTTGCTGGGACGAGGAAGAGTGGGAGGAGGGCGAGACGGAAACGAGCCATCAATGGAAGGATACAGATGATCGCTATCATGCGAGATACCGGAACACGTCATATTTTGGTAGGTGGGTGAACACAGCAAGTGCGCTCCATGGCGCGGGACACTTTTCCCGCGCTTTTTAGGTCAAACACGTAATTTTTCCAGTAATGACTGTGGCGGTGGAATGCGATGATGAGACTGGAGATTTAACAGTGGTGGATACTCGTTGTACTAGGTGCCGTGCTGTTCGACACTTGCCATCCACGTATTGTCCACGTTTAATGAGCTGATTTGCTCGCAGAAAGCGTGTCTGCGAGAGGAAAATGCATACAACGGGTGATGCCGATGAATATGTAATTTTTTTGTTTTTGCAGTGGAGCGCGTTTGTACTCACTCCACGAGGAAATCACGTGGTGTGAGAGTGTCTTTCGGATTGATCTACAAAAAATGCGGTAGAAGAGACACAGAGTTCTCAACTGTGGATTATTAAGAACGTGCTCACGACAGACATTTTTATGGGCAAAAAATAGGCATCCCGCATTTTTGGTAGATCAAATCAATTGGAGAATAGTAAACCTTTTTATTTGAATATGATCCTTTAAAGAAAAAATAGAAATTTGACTGAATTTCCCGCCAAAAAATTTTCGCAGGTAAAAATTTAAATTTCCCGGGAAAATATTCACGGATATCCGGCTTCCCTCATAAATTGAAATGCAAGATTTTTTGCCGAATTAGGCCAGCCCATATCTGGGGTATATTTTGAAAAGGCTGCGTGTCGCGTCGCGGCTCGATTTTAGTTATAAAAGTAAATATATACGCATTGTCCGTGTGGAGTACAAGACTTTCCCACGCGTTGGTGATTGTCAGTGCGAAAAATTCGAAAATGAGGAAGGCGAGAACCTCGTGAATATTTTCTCAAACATTTTGTTTTTGGAAATAATGTGCAATCGCGCTCTAACGCAGTATCCAAAACTTGAGGCTTCTGGCGGAAAACTCGAAAATCAATTTTTTGCTTTAAAATCGTGAAACAGACGAAACTAGTCGCATAATTCAAATTTACGGTATTGCCGCGCCAGTGCGGTGGATCACGTTTGCACTTAAGAAAATTGGTGAAAATCAAAAATTTGGTTTATTTTTGGCAACTATATTTCATTCTCTATTAAATTCATACTGTACACGTGGAAAATCATTGATTTTCCCGAAAATATAAATGGAAGATGCAAGCGCGCCCTATTGTGGTTCGTTAAAATTCGAAGCGTAACTGAAATCGAAATTTTTTCTCGAAAAATTGCAGTGTGCCCGTTGTAAAATATCGTTTTTGGAAAATTTAATATTTAGAAGTGCGGATGCATCCTATTGTGCGCTTCCAATAAACTTACACGCTGGCATGGGATCCGAATTTTCGCGTCGCTTCCATTGACAATCGCCCGTCTACTCCACAAGGACAAGTGCATTTAGTTTTAAAACTAAAATCGAGCCGCGACGACGCAACGCGCTAAATCTACCCCAGATATGGCCTCAGGCCTTCTAGTTCGGCAAAAACTCTTCCATTTCAAAATATGAGGAAGGCCAGAACCTCGTGGAAAATATCGATTTTTCCGTTTCCACGTGGCCAAAGGAATTGCAAGCGCGTTCCAGGAACGTGAACTCGCACATTTTCCATTTTTTGTTCTCCGAAACGTGGGTACACCCGCGAGTGTGCTCGCTGGCAAATGAGCCAAATCGACGTGCGAACGTGTTGTGATTGTATGCTCAATCCGTCATCACCACTGGTCACCTATTTATGAGCGAAAAAACCGGGGAAAAAAACACACAAAGACAACCCAAAACTCAACAAAACAAATAATTTTACAGGATTCAACGAACACAACAAAAAAAAGAAACAATGGCAATTAAATACGGAAGCTGCTGCCAAATATGCTGCCAAATTCAAATTCTCGCTAGAACTTGTACACACGATCTTTATTGAAAACGGTGATCAACGGGCACCCACCACTCTGACCTTTTGAAAATAATTGTTTTAATGATTTGTGTCATTAAAAACCTCGGCCACGGCCGCGACGCCGCCGCTCCGCACGCAGCTGCGTCGGCGGTGGGGTGGATCCTGAACTTATCCCTCCAGCTCGTTATCGTCGTCGACCACCTCGAACAGTTAGCCTCAAATAGAAATCTGAAAAAAATTAATTGGTTTATTCTTTTTGAAAATATATAATTTTATGTTTGGGCGTCTTTGTGGCCTTCCTCATTGCCTTTTTCGCGCGCTCCATTGACAATCGCCCCCCTATGTACTCCAAACGGACTAATCACATCTAGTTTCACAAACGAACGACACGCAACGCGCGTGGCCTAGTTCAGAAAAACTCTACAATTTCAATTTATGAGGGAAGCCAGAAATCCGCGTGCGTTTTATTGATTTTAATTGATTTTTTTACTTTCGAAAATCCCGTTCCGGAGAAGCACAAGGTTTTGCGCGTGTCGGCGATTCGATCCCTCGCTTTACCCCATTATCTGCAAAAAAAAGTACTATTTTTTTTTGTGTAAAATTCCCAATCTGCGAGGGATCTACAAGAAAAATTTTTTGTCCTTTTAATATTTTAATGATTTTTTCAGAGTGATCACATTCTTGCAGATCCTCTTTTCGTGGGGCCTCATAATTTTTCAGTGCTTCACATTTATTTAACATAAAAGTGATTTCTTCATAAAAATTTGAATTTTTTGCCCAAAAATCGAGAAAACCGCCGCTCCGGCTCTTCTTCCGTGCGGCACTGTGCTTTTTGCAAGCTGGGCACAGTATTGTAGGCTTGAGTATGGTCTTCCTTGAGCGCTTGAGTCAACTACGAAAAAAAAAAAGGACTTTCTTTTAAATTTATGTCGGAGATACCACATTCTTGCAGATCAGGGGATCTTTTCGCGGGCTTATTTTTCAGTGCCGCTCGGAAAAAGAGGCGGAACGTCGTGACGCACGGTTTTTTGTCACGATTACAGTTTGACTAAAATTGTTGATTTTGGATCATTTTCGTTGATTTTTTTCGAAGCTGATTTCGGCAAAAAAAAAGTTTTCGCCTTTTTTTGGACAACGAAGAGCCAAAATATCAATAAAAATGAAAAGCTAACTTCATAAATTTTTTAGGATTTTTACATTTTTTTTTTTGAATTGAAAAATGTTTTTTTTAGGTGTTTTTGGTGAAAAAAACTACTTTTTTTAGCTAACAAAAAATATCAAAAACTAAATGACCAAAAATCGGAAAAAAAAAACGCCGCGCCGCCTCTTTTTCCGTGCGGCACTTCGCCATTTGGAAGCTGGGCATGGTTTTGTAGGCGTTGTCATGCTGTCATTACTTGAGCGCTTTGAGGCAAAGACTTATGGGAGAACGGTGATTTAAATCCAAAATTGTCCCGGTGGCGTTCAGGAAGAGACGCGGGGGCTTCTGAAAAAAATTGTTGAAAGATGCAAAAAATCTGAAATTTTAGAGCATTTTTCTGAAAAAAATGCAAAAACCGAAATTTTTGAGCATTTTTCTGAAAAAAACGCTAAAACTCTGGAAGCGCATTTTAGATCATTTTTCTGAAAAAAACGCTAAAAATCTTAAAATTCTGAGCATTTTTCAAAAAAAAGATTCTTGTGCACCTCTGTGAAAACTTCATCCATGATGGTAATTGAAAAATAACAACTGTCCAAAAGCATCGAATTCACAGTGTCGAGTTGGAAAACGCCGACATCTTCGACTACCCTAAAATGCTCATAATGGGGAAAAGCTCTAAAAGCATCGGTGGGCTTCACGCATTCCTCGCGTTGTGTTCGCTCCATTCACAATCGCCCCCGTGTACTCCACGCGCACAAGTGCATTTAGTTTTAAAACTAAATCGAGCCGCCGACACGCAACGCGCCGTAAATCTACGAAAAAAAAAAGGCTTAATTGTTGCTGAAAAATCGATAAAACACGTTAAATTTAATCAGAAAAATCAATTTTCGCACAATAAAATTCGCAAAAAAAAAAAATGAAATTTTTTCGCTCATAAAATTTGGCGATGCTTCAGTTTCGTCTTAGGTTCACCGACCCGAAAAATCAAATTTGACGCGCAAAACTTGAATTTTCGATTGATTTTTGATGAAAAATCGATAAATTACGGTCAATTTAACCAGAAAAATCAATTTTTAACGAGAGAAGCCAGAAATCCGTTGAAAAAGTAAAAAATCAAAACACAAACATTCGAGAGAGTCTCTACAGATGACGGAGACAGGGAACGCATTTTTTCAGAATTTTTCTGCAAGTTTAGGTCCAAAACTGACGAAATAGAAGACACTCCGGGAGCACACTGGCAATGTCATGAAAAAAAATTAATTAAATGCTAGATTTTTAGCATTTTTTCAAAAAAAATGCAGTAAAATTTCAGATTTTTAGCATTTTTTTCGGAAAAGTACACTGAACATCATTTCAGATTTTTATTTATTTTTTTTTGAATGCTACAGACCGAATAGTTTGCCAGGCATTCGAGGAGGAAATCGGCGATGAACTCTGCCACGTCGCGGCATTCGATGGGCGGGGGCTGAAAATATGCAATTTTTTGGCCTAAAATTTGGTTTTTTCTGGAAAATTCTCTTACCCCGATAATGGGAAGGTTTTCGTCTGCGGAATGCTTAAACTAACATACAGCCCTCGGAGCAATTCTCCACGAATTGGAGCCACCTCCTTGGCTTAAGTGAGAGATCATAGATGAAACTGAGCCGCTTCACCATTACGATGCTCTTGCAGCGTTCACGAGCGTTCAGCGTGTTTTTCCAGGATACTCTGAAAAAAGCGCTAATCCTTAATTTTAGCCAAAAAATCCATTACTCAATTTAGCAAAACAATCCGTTAATTTTAGCCAAAAAATCCGTTAATTTTAGCAAAATCCGTTAATTTTAGCCAAAAAATCCGTTAACTTTAGCCAAAAAATCCGTTAATTTTAGCCAATAAATCCGTTAATTTTAGCTCAAAAAATCCGTTATTTTAAGTCAAAAAATCCGTCATTTTTGCCAAAAAATTCGTTATTTTTAGCCAAAAGTTCGCTAGTTTCGGCCAAATATAATCCGTTAATTTTAGCCAAAAAAAACCGTTATGGGGTTCCAAAAAATCCTTTAATTTTAGCCACAAATTCGATATTTTTAGCAAAAAAAATCCGTTAATTTTACGCAACGAACCGTTAATTTTAGCCAAAAAATCCGTTAATGTAAGTCAAAAAATCCGTTAATTTTAGCCAAAGTACAAATCCGTTAACGTTTAAGTCAAACCATTTTAGCCAAAAAATTCGTTAATTTATAGCCAAAAATTCTAGTTTCAGCCAAAAAAATCCGTTAATTTTAGCCAAAAAAGAACCGTTATTTTTAGCCAAAAAATCCTTTAATTTTAGCCAAAAATTCGATTAGCAAAATCCGTTAATTTTAGCCAAGAATCCGTTAATTTTAGCCAAAAGTCCGATAATTTTAGCCAAAAATTCGATATTTTTAGCAAAAAAAATCCGATAATTTTAGGCAACCGTTAATTTTAACAAAAAAATCCGTACTTTAATAGCCAAAAAGAAATCCGTTAATTTTAGTCAAAATATCCGTTAATTTGCCAAAAAATCACCACGTTAATTTAAGTCAAAAAATTAATTTTAGCCAACAAAGACCCGTTATTTTTAGCCAAAAAATCCGTTAATTTTAGCCAAAAATTCGATATTTTTAGCCAATTAAAATCCGTTAATTTTAGCATCCGTTAATTTTAGAAATCCGATATTTTTAGCAAAAAAAACCCGTTAATTTTAGGCAAAGAACCGTTTAGCCAAAAAATCCTTTTATTATAGCCAAAAAAATATTATGTCAAAAAATCCGTTAATTTTAGCCTAAACAAATCCGTTAATTTAAGACAAAACCGTTAATTTAAGTCAAAAACTAATCCGGTAATTTTAGCGAAAAAAGAACCGTTATTTTTAGCCAAAAAATCCTCTTCGCCAAAATTTCGATATCTTTAGCAAAAAGAATCCGTTAATTTTAGCCAAAAATCCGTTAATTTTAGCCAAAAATCCGTTAATTGTAGCCAAAAATTCGATATTTTTAGCAATAAAAAATCCGTTAATTTTAGGCAAAGTTAATAGCCAAAAATTCGATATTTTTAGCCATAAAATCCTTTAATTTTAGCCAAAAATTGCTAATTCTTTAGCAAAAAATCGCTATTCGGCGTTTAGCCAAAAAATCGGCGTTAATTTTAGCCAAAAAATTCGCTATTTTTAGCCAAAAAACTGTTAATTTTAGCCAAAAATAGACCGTCGATTTTAGCCAAACAATTAGATTATTTTTAGCCATAAAATCCCTAAATTTTAGCCAAACAAATCTGTTATTTTTATTAAATAATTCGTGAATTTTAACCGGAAAGTCCGTTATTTTTACTACAAAAATAGCGAATTTTCGCCAATTATAACCAAAATCTCTCGATTTTTTGCTCAAAAATGCACCTAATGTGCGTTTTTCCTTTTTTTTGGCAGTTTCCCTACTTCAATAGCGAGTTTGCAGGCACGTCGTCGTGCAAATTTTGACTTCGATTGCAACAGAATCCAGCAGAATTCGATCGTCAGTCACTTAATACATTCCAAACAATTTTCAGATCCTTTATGGGCACTTCGATGTAATCTGAGAGAGCAAACACGTTAGAATTGCCAGGGTTTACAGCCCTCTTTTAATCACCATCCAACTGGAACGCGAGGTCCATCTTTGGCTGCCATACCTTCACCCGCTCGCCGCCACCCTTGCAAATGTTGTGGATAAATTGAACGGTTCACTCGAAATTCTCCAGATCGCCGTGCTCGACGAGCGCGTTATTCGATGGGTGTGCTCTTTCCGGCTTCTTTTCCTTCTGAAACTGCTGTTTTTCCTTTTTATTTTTTTATGTCGCAAAATTTTTTTTCCGAATTTTTCACGGCACCAACCTGAACAGCGAATCTTCGAAAAGAGACGAAGCGATTTTGGGCTTTTCAAATTTGAAAAATTCAAAGAAGTTGTCACGGAACTAGCCATTTCGAAGTCGAATTGATTAAAAATCAAAAGCAAAAAATTTCGATAAAAAACAGTGTCCGAGAGGAGTACACGCTTAGCCGGGGAACCATGCGCGGGACTCGCACGGAAGAGACGAATTGAAGAACAGCTCGTAAATCCTGTTCCACGCTTTTTTTTTAATTTTTTCAATTCTACTTTTTTCCCAGAAGTTCTTGAAAATATCCTTTTGCAAATTTTTCGGAAAAATGCTCTAAAATTTAAGATTTTTAGCGGCGATTTTTTTCGGAAAAAAATGTTAAAATTGCAGATTTTTAGCATTTTTTCACAAGAAATGCACTAAAATTAATATTCTTAGCATTTCTGCGGAAAAAATTAGCTAAAAATCTTGCACATCAAAGACTGAAAAGAATTTGTTGTAATATTGCATGGATGTTCTGAGGTTTTACATCAAATCTGGGTTCCATGAAATTTGACGTTTTTCACTGAAACATTCTACAAAAATAATTTCTGCGCTCTCGCAAAAGTTAAGATGAAATAATCGCCAATTTTTCAATAGTGCACAGAAACCGTCAGATTTTTAGCATTTTTTCGCAAATATGAAAATTTTAGATTATTAGCAATTCAGAATGCTCTAAAATTTAAGATTTTACCTTTTTTGAGAAAAATTCACTAAAATGCAAGATGTAACTTTAAACATTTTTTTGCAAGAAGCTCTAAAATCAAAGTTTTTTAGCATTTTCTTCGGAAAAATGTTTGAAAATCCCTTCGTTAACGCCTTTTTCGCACTAAAAGATGCTCAAACTAGTTTAAACTTTCAGAGTTTTCCCATGCTTTTGCCCCCTCCACTTCACAAGAAACAATGAAACGAATATGGCGGGATAAAAGCGAAAATTCGGGGAAAACATCATTTTCAATGCATTTTTCATCGCGAAAGCCGAATTTCATTAAAAATGGCCAATTTTTGTGCCAGGTTTCCCAATTAATCTTGTATTTTCGATTAACTCAACCCCTGCGCAGAGAAAATCACAAAATGCAATTGTTTGTGTAAAGCACTTCTCTGCGCGTTTGCGGCATCCGATATGACGAGCAACATATATCTTTTTTCTGGAGCCCTTTATTTTAAATTTATCATTTTTCATGCATTTTTTGAGAAAAAAACTCCCCCAAAATTAACCTAGAAGCCTTGGAAATGAACTTGAATTTTGTGAAATTTGACGTTTTTCAGCGAAAAATTCTCAATCTTTAGTGCATTTCTGCCGGAAAAATGCTAATAATCTTGAATTTTAGTGCTTAGTGGAAAAAACGTTAAAATCAAAATGAAAGAATTTGAAATAAAATCAGAGGCTTTAAAATTTAAGATTTTTAGCATTTTTCCTGAGAAAAGCTAAAAATCTAATTTTTATAGCTTTTTTGTTGAAAAAATGCTAAAAATCTTAAATTTTAGCTCATTTTATTTCAAATTCGACATTTTCATTTTGTATTTAAGAAAAAATAACCTCAAGGTCTGAAAAATATCGAATTTTGAATGAAATTTGACATTTATCAGCGAAAAATTCTCATTTTTCCGGAAAACATGCTATCTTGTAGTGCATTTTTCCTGAAAAAATGCTAAAAATCTCAATTTTTAGTGCATATTCCCGGAAAAATGCTAAAAAATAGTTCTTAAATTTTAGAGCATTTTCCAGACAAAATGCTTAAAATCCTTTTCAGAGAAAGGCTTTATTAATGAAAAATTGCGCTAAAAATCTCTCTAAATTTTAGAGCATTTTTCTCGAAAAAACTTAAAATCTTGAATTTCAGTAGTAAGCATTTTTTTCGGAAAAATGCTAAAAATCTCAATTTTTAGTGCATTTTTCTGAAAAAATACTAAAAATCTTGGATGCTAGTTTTAGAGCATTTTCGCTGAAATATAACAAAAATTTTAAATTTGCATTTTTCCGAAAAAAAAAACGCTAAAAATCTTGTAATAACTGACAAATTTCGAATTTTGAGTAAATTTTATGGCATGTTTTTCGAGGTTTTTCCTTGCAATTTGTTTTCACCTAAAAATTCGACAAAAATGAGCATTTCTGAGCTCTTATATGGCAAAAATTGACAAAAATCGTCAATTTTTCAATAAAAATTGCCCAAAAACCTTAAAATATTCTGAAAAAAGCCGAAAAAACCCCATTTTTTAGCCATTTTCTATAGTATCTTACATTGTTCTCAACTTTCTTCACCTAAAATCGCCGGAGATATTAACATAAAATACCCTTTTTTTTCAGCGCAATGGATTATGAGCCAGGAGGATGAAGCAGCGAAACCAAGATCCGAAGATTCGCGATTGGTAAAAAGTGGGGATTTCCGTGAAATCAAACTCGATTTTTTGTGAAAATATAGAAAAAGCATGAGTTCACAACTGCTCCAAAAACCGAAAAATTTCACTAAAATCTAGAATTTTTGCCCGACTCGAAAACATCAAACGCAAAAATCGCCAAATTTGTGAAAACTAGATTTTTATTTTTAAAAAATTCTAAAAGTTCATAAAAATCAAAAAACCGGATTTTTTTTCTTAAAAATTCTGGAAAACTGTCTAAAAATCTACTCAAAATCAGTTTGTAGAAAATCTGAAGAATAGTCTAAAAAGAATTAATAAGTTGGGAAAAAATTTGAAAAATTACGAAAAAAATCAATATAAAATCGGTTTTGAGCTTGGGAAAAAAAACCCTGAAAAATTGTCTAAAACTCTATAAAAAATTGGATTTTTTAAATAGAAAATCTCAAAAACTAAGAATCAACAAAAAATCGAATTTTCCGGTGGGTGAGAAAACCTGAAAAATTATCAAAAACTTGGTTTTTATCAGAACATCTGAAAAATTACCTAAAAAGCAATAAAACATCAGGGGGTTTTTTTTCTGGAAAAACTGTAATATAGCCTAAAAAGCAATTTAGAAAAAAGTTTTTTTTTTTATAGAAACTACTGAAAAATTATCAATCAAAACCACGAAAAAAGATACATCTTTCGCTTATGTCCAAAAATCCCAAAATTTGCATTAAAAACTAGATTTTTCCGTATTTCAAAAAAATTCAAATTGCCTGAAAATCAATAAAATTGTTGTTTTTTTTTGGAAAGAACAACCCAAATTGGCTAAAAATCCGCAAATTTTTATGCAGCTCAAAGAACGAGAACTCAATGGTCGCGAACCATCAAGCTTTTCTGCCTCCTGGGAGCCGGCGACTCTGGAAAATCGATTTTACAACCAGATGCGTATCATTCACGACGTAGGATATACGTCTAAGAGAGAATAGTGTTCAGAGGCTTGTGGAAATATTATTTTGGTCAGTGCTCCGATGCACTGAACAATTACCGGAAATTGGCAAGACCAAAATTCGTGGATTTTAACCAGAAAATCCGAATTTTAATCAATAAAGGCTAATTTTAGCCAAGCAAAAATTCGCTATTTTAACCAAAAAATCCGTTAATTTTAGTCAAAAAATTCCCTCATTGTTAGCCCAAAAATCGCTATTTTTAGCCAAAAAATCCGTTAATTTTAGCAAAAAATGTCGCTATTAGCCAAAAAATCCGTTAATTTTACACCGGCAAAAAATCCGTTAATTTTAGTCAAAAACTAGCTCCGCTACTTTAACCAAAACATCCGCTATTACCAAAAAATCCGTTAATTTTCGGCAAAAAATTCGCTACTTTTAGCCAAAAAATCCGTTAATTTTAGCCAAAAAATTCGCGAATATTTTTAGCAAAACATCCGTTAATTTAGGCAAAATCGCTCATTTCTAGCCAAAATATCCGATAATTTTAGCCAAAAAATTCGCTATTTTTAGCCAAAAAATTCGCTGTTTTTAGCCAAAAAATCCGTTAAATTTAGACAAAGACAAATTATTTTTAGCCGCACGACAATTCACCAATTTTCGTTTAAGATCCAATTTTTGACAAAAAAATACACCGAATTTACTCAGACGCAAATTCTCCCTTTTATGGCTAAAAAATGCATAAATTACACAATTAAACCAAAAATTACCCAATTCCCAAAAACTCTAATTTATTTACCAAAAATTCTCCTATTTTTTGTTGAAAATTCTCCAATTTTTTTGCCAAATTTTAACAGAAAAATCTATAAAATATCAGGCGAACCTAATTTTGGTCAAAAATTCACCTATTTTTGTTCAAAATTCTACTCACATTTTACCCAATATCCACCAAATTTTAACAAAAAAAGCTAAAAAATTATTCAAAAACCTAATTTTCGCCCAAAATTTTCCATTTTTACTCAAAAATTCCGATTCTCTTTTTAACCAAAAAATCTAGAATATTAGGTGAAAAATGCCTAATTTTGGCTTAAAATTCACCGATTTATGGCAAAAAAAAGCCTCCAATTTCTGCTTAAAACTTCTCTGCTTTTTACCAAAAAACTCTAAGATATTAGGCGAAAATCACTAATTTCGGCGAAAAAATTACCAATTGACAAAAGAAACTCCAATTCCAATCACACAAAAAGTTCACAAAATTTACTCAAAAATTGTCTGTTTTTCACAAAAAAAAAACCTACAAAATTAGGAGAAAATTCACATCAATTGCCAAAAAATCCCTAATTTTGGCCGAAAAATTTGCCAATTTTGTTAATTCAGTCCAATTTTCGACTAAGAAAACCACGTGCCATTATTTTCAGCAAAAAGTTGACCAAGTTTACTCAAAAATTGATACAAAAAAAGTCTATTAGGCGAAAGATCCCTAATTTAGTCCAAAAATACACCGATTTTTGACAAAAAAAACTCTAATTTCAGCAGAAACTTCAAAACCATAGCCACAAGTTCACTGTTTTTTACCAAAAAAATAGAATATTAAGAGAAAATCCCTAGATTTGTCCAAAGAATTAAACAAATGCCAAAAATGCTCTGTCCGTTTTTTACCAAAAATTCTAGAATGAAATTTTTTAGGCAAACAACATCCCTAATTTTTCCCAACAAATTCACCGAATTTAATCCAAAATGCTCTGTTTCAAAAACTCTAATTCCAGCACAAAATTTACCAAATTATAGCCAAAAACGCTCTTTTTTTTCCAAAAAAAATCTAAAATAGCTTAGGCGAAAAATCCCTACAAGATTTTGTCCAAAAATTCAGCAGATTTTTGACAAAGAAACCTCTAATTTCAGCAGAAACGTCACCAAACTTTCATAGCCAAGCAAATTCACTGTGTTTTTTACCAAAAAAATAGAATATTAAGAGACAATCCCTAAATTTGTCCAAGAAATTAACCAAATTATAGTCAAAAATGCTCTGGTATTTACCAAAAATTCTAGAATATTAGGTAAAAAATCCGTAATTTCCCAAAAGATTCACCGAATTTACTCCAAAATGCTCTGTTTTTGACAAAAAAAAACTCTAATTCCACAGTCAAAATTTACCAAATTATAGCCAAAAATGCTCTTTTTTTTCGAAAAAAAATCTAAAATATTAGGCGAGTGAAAATAATCCCTAATTTTGGTCTAAAAAATTACACCAATTTTCCCCAATTTAAGCTTAAAATGTTCAATTTCTAACCAACAAAAAAACTCCCAAATTTTAACCCAAAAATTCCCTCGAATTTCACCCCAAAACCGTCCAATTTTCCAGTCTTTCAACGCCAACACAGGCTATGGAGCAGTTAAAAATCAGCTTCACACACTCGATAATCAGATGCCCGAAAGCTTCTAATGTTCAGCACAACAGGCGAAGAGGATGAGCTGTCGAGGTCGTCGGGCTCATGAAGCGTGTTTGGTTCGGGAATTCAGAAAGCGCTCGAAAGGTGGCGAAATTTCGCTGAAAATTGAGAAAATTCGAGGGATTTTCGCTGAACATCGAGAAATTTCGGTGGAAATTAGCTTATGTCCATGAAAAAATCGTTAAAATCCCAGAAAATTGCGATTTTGACTATTTTTGAGCATTTTTCGCCTTTTTTCCATGAAAAATTCAACGAAATCTTTAGGTCATACTCGCTCTCAGGAAAATTACCGCGTTTTTCGATGAAAAATTCGTTGATATTCGTTGAAAATTATCTATTAGAGATAATTAAAATTTAAAATTCCAGACAAAAAAATATTTTAAAATAATTCGAATTATTTTTGGCTCACACTTTCAAAAACCTCTAAATTCTAAAAAAAAAATTTTGGAGCCCCTTTTCCGGTCTAGAAAATATTTATTACCCAATGATCAAAATCCGGGAAAATTCAGAAATATTTAAGTTTTTGGCTATTTCTGACCTCACTCTTACTCCCACACAAAAATAGTTTTACCAAAAAAAACGGTAACAATTTTTGTCAAAAATTCGACAAAAAAAGTACCTTTCTGGGAAATATTTTTAATAATTTTCCCCTGTTCCGAATATCGATGTGAAAAAATTCAGAAAAATTTTCCGCGATTTTATATGATTTTTTGAAAATTGAACAAATTTCAGTTTTCCCCCCTAATTCCTATTTTAGTTCAATTTGATTTGTTCGATGGACTTGCACACGTTTTTATTAATCTATTTTATTTACTTTTGTTGATTTTTCCACCTCCCGATTTTTAATGTTTTCGGTGTATTTTTGCTTGAATTTTAGCACTGGGAAAAGTCAAAATAAATGCAATTTTCGATTAAAAAGCACGCTGCCCGGCGTAAAAATGAATAACGACTTTAAACGATTTCAAACCTGAATTAATTAATTTCACTGATTTGCGCATGTACGCGTTCGTAGATCAGTGAAATTAATTAATTGAGGTTCGAAAACGTTTACGGGCAAAGCACTTTTTAATTTTTACGCCTGTAAAGCGTGCTTTTTAATCAGAAACTTGCAATTATTTTGACTTTTTCTATAAAATTCAAGCAACAAAAAATACACCGAAAGCATCAAAAATCGATGGAAAATAACAAAAAATAAAATTCTTTAAATAAATTTAAAATTGCGCGAGCGCGCTCCATCGAACAGAACACCGCGGTAATTCATATAGGAATTAGTCAAAGACTGAGATTTTTGAGGCACCACGTTACGGTTTGAAAATCTGTTCCAAAAAGAAGTTCTACGTTTTCGGGATCTGGCACCGTGGCAACTGCGGTTTTCTCGATGAAAAACGTAACCACGATGCGATGTTACGCGTCGCGTGTTGTTTTGCGTTCAGAAAGTACATTTTTTGAAATTTTCTTCTTGATCCTGAGAAACGCTTAACGACACGCAACGCGTAACAGCGGAGCATCGATGTTACGTTTTTCATCGAGAAAACCGCAGTTGGCACGGTGTCCGATCCTGAGAACGTCGATCTTCCTTTCGTAGATTTTCAGAATGTAGATCTTCTTTTGGTAAATATTCTTTTCGTAGATCTTCCTTTCGTCGATCTTCAAAATGGAGATCTTCTTTTGGTAGATCTTCGTAGATCTTCTTTTCGTAAATCTTGTTATTTGAGCGTAGATCTTGCTTTTTGAACAGACGATATTTAGAACGTGGTGCCTCTGATCAAATTTCAAAAAAGCATATAAAATTGAGAAAATTTCCACGTTTTGAATTTGTTTATCAGCATATTTGGTCATTTTGGTACCATATACCCCTTTCCCCTGATTCCGAACAATGTGAAAAAATCGCTTCAAAAAACAAATCCCTGATTTATATTTACGCTTGAAATTGCGCCGAGTGATGTCAAATACGCGCGCATAAATAAATTCTCGACTTGGAGCGCGTTTGCCTCATTTAATTCCTTCTCCATATTTATTTTTACTTTTTTTTCAGTTTTTCACAGCTATTTTCATTCATTGTTATTGTATTTTATAGGTTTTTTTTATTGAAAAATAAATTTTTCCGTGTGAATTGAAACATTATTTGCATAAAAATGAATGAAAATAGCTGAAACACTGGTCCCAATAAAGTAAAAATATAAATGGAGGAAAATTAAATGAGGCGAACGTGCACCAAGGATAATTTAACGCCTTTGGGCGCGTAAAAAATCTCATGTAGTAGGCATGAAATTTAGGCGATTTCTAGCTTAATTATAACAGGGCGAAATTTTTTTTTTGATTTCATCGATATTCGAATCAGGGGAAAATTTGGAGACCTGTAACAAAAGTTGTGTTATGAAAAAAAAATGTATAATTTCTAAGGACAACTTTTTTTTTGTAGTTCTGATCACGCGAATATCACCTCAACGATTCGGCCGTCTGCTATCAGGGCAACGCGACAGGTGCTCCTAATTACATTCCCACACAGGTATTTTTCAGTGGAAAATTCACAAATTTTTCCACTACTTAAAATTCAAATTTCCTTTGCAGGATGACCCGCCCAAGAATGAATACAACAGGAATCTTCAGGAGACGCAGTCGTTGTCAATACAGATCGCCTATTTTTGTAGATGGGGGAAAACTAATTTTACAAAATTGAAAAAATCGTCGCCGAAAAGGTCTTGAGGGTTTTCGACGTTGGTGAACAGCGGTCCGAACGAAAAAGGTGGATTCATTGCCTCGAGGACGTGACGGCACTCATTTTCTGCGTTGCACATATGTCAGAATATGATATGGTTCTTGTCGAAGATTGGCAGTGCGATTTTCGAGTTTTTTGCTTTTTTTTCGTTTTTTTCCCAAGTTTAGGCTACCGTTTTTAGGTGAAAATCTCGGTTTTCTTGGTTAAAATGGTTTTTTTTTTGGCAAAAAACGCGCAAAAATTGAGGATTTTAGCGTGGCGTAAAATTGAGTTAATTACATGGAAAATTTCAGAAATTGAGTTAAAATTGTAGTTTAAGGATTTATTTTTGTGATTTTCTCGATTTTTGACCGTCGAAAACTGTTCGGAGTGAATTTCATTTATTACGCGCGACCACAAAATGCTGTGAGACCGCGTATTGCACAACATATTTGACGCGCAAAATATCTCGTAGCGAAAACTAAAGTAATTCTATAAATGACTACTGTAGCGCTCTGTCGATTTACGGAAATCGTGTAATCGATAAAGTATTTTGTTTAGAAAAAACACAAAAATGACAAAAAAATACGAAAATTGAATTGTTTCGAATAATCGGGTCCCGATCCCGTAAATCGACACAGTTGCCATTAAATTAAATGAAATTAATCATGTGTCGATTTACGGGACTCTCAATTGATATTCGAAACAATTCAATTTTCTTTCGTTTTTTTTTGTCATTTTTGTGTTTCTAAAAAAAGTTATACTTTATCGATTAATACACGATTTGCGTAAATCGACCCACAATGAGCTACACTAGTCATTTTCAGAACTACTGTAGTTTTCGCTACGAGATATAATTGCGCATCAAACATGTTGTGCATGACGGATTCTCAGCATCTGATTTTGTGGCAAGTCGCGCGTATTGAAAAGCTAAATAATCGATATTTTCTGATTTTTGCGCCGAATTTAATTTTTCTTGTTTTTTTTTCTGCGAAAACCACATTTTACTGACTAAATTCAGGTTCATCCATTTGTGCAAAAACTCCGTCGACGAAAGTGTATTTTAGCGTACTTTTAATTTTAAATTTTTTTCGCTCTGAAAATTATGAAAACAAAATTTTCTCGATTTTTGAACCGAATAAAACGTTCAAATTTCAATTTAAATCGAAATCGGGAAAAAATTTTCCGATTTTTACACCGATGATTATCGCTAATTTTTCCCACACCACATTTTTTGCGTTTCAGAATCGTATGCTAGAATCGCTAAAACTGTTGGACCGATTTGCAACAATAAATGGTTTGTCGAGAAGTCGATTATTCTATTTCTCAACAAAAAAGACTTATTCGAAGAGAACATCGTTAGAACTCCACTCATGCTTTCCGGAATATACGGGCGCCAATAATTACGAAGAATCTGGGTACATTCAACAACACTTTGAGGATAAATGAATAAGAGGACTCCTGCAGAGAAAGTTGGTGGTTTTTTTGAATTCACTGCACTTTTTCTCCTCACGAGGGGACGAGGAAAAGTGGTTTCTAGGTAATGGCCGAGAGGCCGACAAGTACTTTCCAGCAACATGGCCAGCGCATTTAATCTTCACGAGCTTTGTTTTCCGCCTGTTTGCGTCTTTTTTCATCGATTTTTTTCGTTTTTTCGTGAGTAAAACTGATAGAAAATAAGTATTTTTTGCCGATGCTAAAACAATTTCCCTCAAGTAAAAAGATCATGTATTCAGGCGGCAAGCCGGGTGAAATGGGCATTGTATGATGGATTACGGGAATACAAAACCTAAACTTTTTCTGAAACATGAAACATATGATGCTTAGATGCTGAAATTACTTGATTTTCATAACGAGCGGACCGGACCGCTGAAAAGTTTCGGGCTCAGGTTTCCACAAATCAACTTTTTGTGCGAAAAGCTAGACTTTTTCACCACAAAAAGTTGAATTTTGGAAACCTCAAAACTTTTCAGCAAGGCGGTCTCGTTATGAATATCAGGTAGTTTCAGGATTTAAGCAGCATATGTATCATGATTCGGAAAAAGTCTAGGTTTTGTATTGCGGTAATCCATCATATTGATTGCACATTGTTTCTCCGTAATCTGCTTGCCCACTGAATGCATAATTTTTTTACGTGGATATTGATTTAGCATCTGCAAAAAATATTTATTCATCAGTTTTATTAAAAACGAAAAAAATCTGACGAAAGCGGGAAAACAGGCGGAAAACAAAGCAAGATAAATGGCAAACTTGTCGGACCCTCGGCCATGGCGTAGAAACCACTTTTCCAAGTCGTCCCTCGTGAGGAAAACCATGTTGAAGTGAGCAAACTCAATTTTTGAATTTATTTTTCATGGAAATCGGAAAATCTTCAATTTTTCCTAATCAATGCCATCTCTACAGAATCAAGAAATCTACACCCAATTCATTACGTGCCACCGACACTAACAACATTCGATTCGTTTTCGATGCCGTCACCGACATTATCATTTATCGAGAAAACCTCCGCACGTGCGGGCTCAAATTTTTCCGCTAAATTTTTTCCGTTTATTCCCCCAATATCACCTCCGAGACATTTTCCAGTAATTATGTCACTGATTGCCACACACAGCCCTCCTCTCCCGTCTCCGCTGTGCAATGCTACGGATTCTCTTTTTTTTTCTTTTTTTTTCCTGAAATTCCAAGGGTGTCGTTGAAAATCGAAAAATTTGAAAAATTTGGGTTCTAAATTTTAGGAAAAGCCAAAAATACAATTTTTTTGATTATTATTCCGGAGAATTCGAAAAATTTCGATATTTTTTAAATTTTTTACAAAAAATTCGAACAATTGCGTTGGATTTTTTCAGGAAAAAGCCAAAAAATTACAATTTGTGTTTAACAAAACGAAAATAAACCAATTTTTCTGATTTCCGGAAAAATCAAAAAATCTCGATTATTTCCAGAAAAATTCGAATAATTTGGGGCTTTTTCAAAATAAATCTTAAAATTTGATTTTGTCCAGGAAAAATCGATAATTAACTGTTTTCTTTTTTGGCTTCTTCCGGAAAATCCAAAAATTTTGCATTTTTTGGATTTGTTTTCAGAATTAAAATTGGAAAATGGATTTTTCAGGAAAAAGCCTAACAATTTCAAAGCTTTAAAAAAACTTTAACAAATTGATTTTTGAGGAAACAACGAAAAATTTTCCGACATCTTACGTTGATTTTTTTTTTACCGAAAAACAAATTTATTTTTTCCAGGAAAAAGCGAAAAATTTTCAATTTTTAAGGAAAAACTCGAACAATTTAGCCTGATTTCGAGTTGATTTGCGTTTATTACGGAAAAATCGAAAGTAATTTTGGTTTTGAGCTTAGAGTGAAAACCCATAAGTTCAATTTATTTTTCAGAAATCCAATTATTTCAATTTTTGAATTTATTCAAAAAAAAAAAATGTCGATTTTTTCCAGAAAAATCGAAATTTTTCGTTTTTGAATGAAAAAAAAATTTTCCTTCAATTTTTCCTTTAAAAAAAATAAATAATGTTCGAATTTCCATGAAAAAAAGTCAAAAAAATTCAAAATTTTCCATTTTCCCTGAAAAGTCAAAATTTTCCGAGTTTCCTAAACTAAAATCCCAATATATTTTCCGGATTTTCCAATTTTCTCTGAAAAATCGAGGATTTTTTCCCGCACACCTTACCCTGCTGTTCACGTGGTGGTCAGGTTGTCTCATTTTGTGATCTACAAAAAATGAGGCCGGAATCTTTCCTCCCCCGGGAAAATCTGACGTCAGCGCACTCGTGTAACCATGCAATCCCCTGCTGATAAGTCTGCGTCTCTTCTCCCGCCGCATTTTTTGTAGTTCAACGTGTAGATCAATAATGAGACCTTGACACCACGTGCCGAAAGCCTAAACCAATATTTTACCGGTAGCTTCTGGCATCTCTACAACCACTGTCTGAAATATCGCGTCATTTTATATTATTATTATTTATTGTATTCGCTTGAACGGCCAAACAATTCCGCCATTTGATTCAAAAAGTAAACATTTCCGAACTTTTTAAAAATTTGAAAAATATTTTTAAAAAATTGTTAGCGTGAAAAACTTGTCCCCCCACCCTGCCTCTCCATAAAAATTAAGTTCGGAAGAATTCAGTCCTTGTTGTTGTAAATTGACGCAATGCGCTTTTTGGTGGTACCTATTTTGCATATTTATCGTCACTTGCGTACGCGAGGTATTGATTCAGATTCCGTCAGTTTTTTACAACAAAATATCGCTAAGCAATCACTCCAGCGCGAAACTTCAAAAGCGAGAAAGGCCAAAATGTTTTGCGTCGCTTTCTATGATTTTATGACGAAAAGCGAGGAAAGCTAATAAAAACAGCGAAAACTTTGCCAGGAAATTTACCGGTTTGCCGCTTTTTTTGCGCTAGAGCGCGATTGCTCACTGAGTTCAAGCGCCCTTCTTATTTTGAAATAGAAGAGTTTGCCGAATTAGGCTATTTTGGTGCGGCACGGCTGGGGTCAATTTACGGCGCGTTGCGTGCCGCGTCGCGGTAGGTGGACCACGCCTTTACCACGCGTAGACGATTGTCACTATAGAGCGCCGAAAATGTAAGGCCAGAAGCCGGTATGAGTGAACTTTTTGTTCATTATTTTTTTTTTCGTCGTTTTTAACGGTTTTTATGTTAAAATCAATAAAAACGGCGAAAATAATTAAGCAAACGATATTCCGGGTTTGGCGCTTGCTTTGCGCTAGAGCGCGGTTGGAGTGCTCACCGAGTTCAAACGGCGCACTCTGGCTTAACTACCCTATTTTGAAATGGAAGAGTTTATTAGGCCTATATTTTGTCCGGTCGGCGGGTAGATTTACGGGGCGTCGCGTGTCGCCCGCGGCTCGATTTTGATTGTAAAACTAAATGTATTTGTCCGTGAGGAGTACACGCGACTTTCCCAATGCCGCGTTGTCCAGCAGGTTATTGCCAATGGAGCGCCGAAAATGCAAGGCCAGAAGTCCGCCGTATAAGTAGCCCATGAATGAGTGAAGTTGTTGTACATTTTCAGTGCACTTTTTGTTTCGTCGTTTTTCTGGTTTTTATGTGAAAATCTGGCACAGTCTCCTGTCATCGAAAGCGCACAAAAAACTGCCTCGCGTTTGAGGTCGCGTTTTTGCTAGCGCATTTTGTGGATTTCTCCGAAATTCAGAAATTACGCGGCAAATGGCGAGGCTTGAATTCCAAATTACAGCCCCGCCTCTTTTGATACATTATCTTCAGGATGAAGATGATCGCTCCGAAAGGTGGGTGACTCTGAATGAAAATACAAGAAAATTATGATTTCTTCAGAGAAACACCATTTTCACCGTTCATTTTTTAATATCCCTACGCCTCCTTCATTTTTTGACCAAATTTTCTCTTTTAATGGTCTTTCATTTCATTTTGTGCTAATAAACAAATTAAGTTCGACATCTGCGAAAAAATTCGTTCAACGCTAAAAAACGACGAAGTTTTTTTTTCAACACTAAAAAGAATATTCACTCCTAGCTCCGCCGGCTGTACCAATGTGCAAGTGCGCCCCAGCCCACTTCGACGCCGAGGAGACTGCGAAATCATTAAAAACAGTGAAAATAACGGAAATTCTGAAATTCCGGGTTTCGTTTGATAATTTTTTGCGCTGGAGCGACTACGATTGCTCACCGTTAAAATAGCGCACGCGCTTCTGGTTTCCCCCATAAATTGAAATGGAAGAGAGTTTTCGCCGAATTAGGTCATTTTGGCGCGGCCCCGACCGGGGTAGATTTACGGCGCGCTACGTGTCGCGTCGCGGATCGATTTTAGGTGTCAAACTAAATGTAGTTGTCCGTGTGGAGGGGGATACACGACTTACACTCCCGTCCGGCAGGCGATTGCAAGTGGAGCGCGAAAATGCGAGGCCAGAAGCCCGTATATGCATTTTTTTGCTGAGGGTCCCGCCACGACATTTACCCTTTCAGTCACGTGTATCAAAGAGGACCGGGCAATTTGGTCAGAAGGAAAATGAGAACTCGCCACGCCAATCAAGTTCTTTTTATCGATGACGGACAATTGCCAAAGGAGGGAAACTCATCTCGTAAGAAAGGGAATTCTTATGAGCTTCGGAAAATCGATTGAAGTATCTGACAAACGGATATGAGACTGTGAGACTTTTTTTAATACTATTGGGTCTCGACGCGATTTCCCACGGATTTCGGGCTTCCCTCATAAATTGAAATGGAAGAGCGTTTACTTGCCGAGGAACTAGGCCCAGGCCATATCTGGGGTAGATTGCTACGGGCGTTCCTTGCGTGTCGCGTCGCGGCTCGATTTTAGTTGTAAAACTGAAGGTATATCGTCCGTGTGGAGTACACGGGCGCTTGCCAATGGAGCGCGCTAAAAATTCAATTTGTGTCTCGCTTTTAACGATTTTATCGATTCTTGGGTGCTGTTCGAACAAGCTCTGAGTCGTGTCACTTGAATTCAATACGGAACACTTTCTTGTGATCAATTTTTGGATGAGAAGCTACTATTTCATGACAAACGGTGAAAATACCAGCTGTCATACACCGAAACCAACCATCAAACCCGAATTGAATCACTTTATTCGGTTAGCAGGAGAATATCGCTCCATCGCAACCATGTTTTCAGCGAATACTTCATCCAACTGCGGCCCCTCCAGCGAACAGTCAAAGAGAAACCTGCGTTGATCATGTTTGGGGATCAGTCGAAACCGCGAGTTTTAAAGTCGAAATAATCGAAGAGGGAGAGCAGCGCTGAAAGAGAATTCGGGGAAGAAGTGCTGAAAAAGTTCCAGAAAATTCGGACTGAAAGGTTAGAGCGGCGGCGGTGAATAACTCGACGGAGTGGACACAGACGGTGAAGGATACTCGGAGACTAAAACATCGTAGCGAGTGAGTTTGTGCCAAACGCTACTCAGATGTACTTCCGCTTCCGTGAGGACACCGCGTTTGATCTCTGAAAATTGCGAGAGTCAGCCCCTTCGTGTAAGTTTCCCGCAATATTTGAAGGTTAAGCAGCGAGGTCCTCATATTTTGAAGAAAGAACTTTATTGCCGTCTAATTCGGAGTCGATTTACGGCGCGTTGCGTTGCTTGTCGCGTCGCGTCTCGTGATTCGCATATTTATCGACACTCGCGTACGCCACGTATCAGATTCCGTGAGTTTTTGCAACAAAAAAATCGCATATGAGCAATCGCGCTCCACTGGAAAACACCCGAAAAGTTTTGAAATTGGGGTTGTCGCTTGTTTTGCGCGCTAGAGCGCGATTGCTCGCCGAGGTTTCAAACGACACTCTCTGGTTTCCCCCTTGTAGACGAGCGTCGCGGTTCGGTCCAGCAGGCGATTGTGAGCGCGAAAAACACGTGGTGTCAACAGTGTCCCATTATGGTTTGATCTTTGATAAATGTGTACGGGAGACGACAGACACCGACTTCTCAACTGATTTCGCGGCAATGGTTAAAAGTGTTCTGACGTCACATTTTTCTGGCATTCAAGACGCGAAAAACTCCCGTATTTTTTGTAAATCAAACCGGATTAGGACAGCCGAACGTGGAAAAAAGGCAAGATGACAAGGGCCCAAAGGTGACCCACAGAAGCCCGGCAGAGTCTCGGTTTTATCAGTTTTCGAGTAGTTTCGCACCACAAAAAGCGTGTGACGTCACATTTCCGGCCGCAAAATTCCCGCGCTTTTTGAAGATCAAACCGGAATGCATTGTTTCAGAATCTACTCTTTGTCTCTCGTTCATTCACCTCGGTTTGGGTATGGTATTGATCGTAACGCTATCGTTTTTTTGTTCTTTTTCAAGTATTTCAAGAAGTTCAACTCGACGGTGAAGAATGGAGATCAGGTGTATAGAGAGCAGGAATCGGCTGAGACTGATGAGAAGACTGAGAAGACTGAGAAGCGCGAAAAACTTTCTATCTGCGTGTGTCACTGCAAATAAAGAAAGGAATTGAAAATAAAAAAAAAAAAAATTTTTTGGGAGTTGCATATATGCATGTGTCGTGGTGTCCGAGTGGATTATTTCGGTTTGATCTACGTTGATAATCTCTCCAAAAAATGCGGGCACTGATTTTGCATGGATAAGAACGTGCTGACGTCACATATTTTTGTGGGCGAATATTCCGGCATTTTTTGTAGATCAAACCGTGATGGGACACGGTCTGGCATCACGTGTACTTGTCGCAATAAATGAGGTACAACATGTTATGCCGTTATCCTACAGTACTATAGGTGAACCCCGCACTTTTTGGCCTCCAAAAATTGGATGTTATAGGTCACAAACTTGTAAGGAGTCGTGGACATGAATGTCAAGATTCAAATTATTCAAGTCAAAAGGATGATAGCGCAGACACGTGCCCCCAACTTCGGTTTTCTACTGTGTAGATCAACAAAATGCGGGATTTAGGACGCTGAGTTCTCCACTGATTTTGCAACAAATTCCCGGAGCTTTTTTGAAGATCAAACCGGACAACCTGACACCAGGTGAAGGAATAAAACACGCTCTTTTGCCGAAATCTTAAGAGTTTCTACAATTTGAAAATCCAGTATTAGATTTTCTGAAAAAAAGTCCAAAGTTAAATAATGGACGCTGCCTAGTCTTTGGGTCCTCCTCTAAAAACGCCCTTTACAAAAAAAATCTATAGTTTCTGAAAAATAAGTGGCAAATCTCTACAATTTTCAATATTTCATACTAAAAAAATCACAAAAAATTATTTTATGGCCGCGCTCGAGTTTTTTACTCTTCCTCGTGGTGTCAGAGTGTCCAATTGCGGTTTGATCGACCGTGTAGATCTAAATTCGGGATTCGAGAACTGAATTTGCATGATTGCTGACTTCACATTGTTTTGGGTAAAACTAATTTCGGCATTTTTAGTAGATCAAAAAAGCCTGGCACCGCGTGCGCAGAGAAGAAAGAGCTAATGAGCACGGGGTGTCAGGAACGGCTTGATCTACAAAACTTGCGGGAGTTTTCAACCCAAAAATATGTGACGTCAGCGCGTGCTTAACCATGAAGAATCAGTTTCAACTCCCGCAATTTTTGGATATCTAGGATCATAGATGAAACCGAAATGGGACACTCTGAAACCCCGGGAATGAGCCAATTGAGCAAAAGTATGCGAACTGAAGGAGGCATCGTTTTATTCGCGCAGAGGTTAGTTAGACGAATTGAATAGGCAAGAAAAAATAATGTTTTGCAACATAAAAGTAATGTACATACTAATGGAAATAAATTAATTATGGGGGAGCTTCATTATTACAAGTCGACGAAGAGCAGCACTCGTTCTTCTCCTCCTTTTCCTTCTCTTTTTCGTTTGGAACGGAGAATTCGACTGGGGTTTCCACATTAGACGGGAGCTGGAGCATCTGAAAAAAAAACGCGAAAAATGGTAGACTTGTCACACGTTTTCCAACCTACTACCTTCTCAAAATAAGACTGGAGAAGAGCGGTAGTACACTTGAGCATGTTCTTCAACAGTAGCGACTCGTAGTTTTCGATCGATTCCTGGAACTTTTGGATCCACACACCGCTCCTTGTCCGCCCTGTCGGCGACATGTAGGGTGTAGATGCCCACGACCTTGGTAGTAGCGGGTTTGGTGAATTATGACGAACGCGAATCTTAGGGACGGATTACTAGAAGAGAAACACACTTATAGTGACAATACAGTAGTCCTAGAAGGTATTGGTAAGGTACTGAGGTACTGACTGCGCTAATTTTTGTACGTTACACCTTTTCCTGGAGTTTTGCAGACCTTCAAGAAAATTCTAGCACTTCCCATTTTCTCCGAAAAATTCCTGCACTTTCCAGATTTTACCAGAGAATTCCCGCACTATACAGATTTTTCTAGAAAATTTTGTTTTTCTCAGAGTTTTACGGCTCCTATAACTACAGTAACCCTACAGTACCCCCCAGACCATATCGCCCCTACCCCAACATACAACCCAATACATCAAAAGACAAAAACTCAAATTTTCCGGAACGTAACCCTATAACTCCTTTAACGTAGACCTACCGGGCCCCTACAGCACTGCTGCAGGACCTTGAGACATAACCCCCTACCAACATACAAATACCTCTTCGAAAGCTGGGAACTCAAATTTTCTATACAGTAATCCCGCTACAGTACTTCTACAGTACCTCCAGTACTACTACAGTACACCGACCATATCCCCCACAAACGCTATACAAATTTTCCTTCAAAAGACAAAAACTCAAATTTTCCCAAACTACAGTAAGCCTAAGCAGTACTCCTACAGTCAGATCCCCGACCTTCCGATATATCCCCACACCAACATACAGCCCAATGTTCCTTCAAAAAACAGAAAAAACTAAAATTTTCCAAAACTACAGTAACCCTACAGTACTCTTACAGCTAACCTCTACAGTACTCCTACAGTACCTGGACATCATCCTTCACCACTTCCAATCTAATACCTCTTTAAAAGCTGAAAATTCGAATATCCTATAACTACAGTAGTTCTACCAGTACTCCTACCTCTACAGTACCACTACATTACCCCCAGTACCCCTACCACATCCCCCCATCTCTAAACCAATATCCCTTCATAAGCACACTACAAAGACTACGTGGACTACAAACTATGTATGGTCAGACGGTTTATTTTTAATATGAGAAATGATGATGAACTAGCTGATATATACTACTATATGTACTGACACTGATTCACCAAAATTAGCGTGTCAATTCAAGATAGGGGTCTTTACGGTACTGGTATGGTACTGGTCCGATACTAGCCCCAGTTCTTTAATACGATTCCCTAAAATTGCTGACTCGGCGTTCCTGGTCGTTGGAGTCCGCATCACTCTGACGCAAAAATCCATACCTCGTTCGGTAATACGATCCGGCGCTCAGATTTCCCGATTGGGACTGGATCCTTTCTGCAACTCTTTGTCTTCAGTAATAAAACATGGAGAGTAATAAAACTTCGCGGGACTCCTCACCACTTTAAGCTTCGAAGGGCACTTTTTAGTTTTAGTCAGCACAAACATGTCGTTCAATAGAAACGCGTACATGTCAACGGTCCGCCCGTTTTCCACAAGCTCGAGGGGGCGATCTTCGTGGATAAGCTCTCGACGCGGATGAGCCAGTAGGTTCTCGCAGAATTGACGGATGAGGCGACGCGGAGGAACTGGTAAAAAATCAAGGGAAAATGTTGCGGGGAAAACAAATGTTTCAACTTTCATCATGGACATAAGACTTGGCAAGTCGCTTATATTCGGCCAGACCCCAAACCTGTGTCTGCAACTGCTGAAGCCTCTCAATTATGAAGGCGCCACTGCACACTATAATCAATCGATCGGTGGCCAGTGTTCCGTCATTGTGTCGATCATTCTCCACCTTTCCCTTACTCGCCTCTTCCTCCGATCTTTTGTGAATCTCGCGGAGAAGGATCGGAAGCCGAGTGATCGTCGTTGGGTGCGTCAAAAGATCCTCGAGCCGTACACGGAAGCATCGTTCATCGGCCAGACTTTATCCGCTCGAATTCCGTGAATCGTTCCTCTTTCTGTCGCATTGAGCCGAAATATTCCATGGTTGCGTAGTTGATGCAGTAGGCTTGGTAGGCGAAATTGTGGAAGGGCGTTTGCAGAACTGGAAGTTTCGCGTTATAACAAGGCATAGTCTCAAGCTATTTTCTCTGCAGCCTATCCCAGCTGTGGTCCTGGTGCTTAACAGTCGTGATTTCTGCTGGAAAACCGGTCTAATCCGGACTACGGAAGCCTGTGTTTTTGAGTCTAAACGACAACATTGTGAGCGGCAACCAGGTACGCTTTTTCATACTACTTTTTTTTAAACTGTTTTTTTGTTCTTTTTCGGCCAGCGGAAGTTTTTGACCCAACTTCGAAATGTCCCTTTTTTTCGCACTTGAGTTTGGGAATTTCTAGAAACTTCCCAGTATTTTCTCTTTTTCCCGCGAAGCCCCTTCTAAACCTGGGCCTAGGCCTACGCATAAACCTAAGCCTACGCCAAAACCTACGTAGCCTAAGCCTAAAAAGCCTAAGCTTAAGCCTAAGCCTAAGCCTAACCTAAGCCTAAGCCTAAGCCTAAGCCTTAGCTTAAGCAGCCGAATGCCTAAGCGTAGGCCTAAGACTGAGACTATGCCTAAGTCCCAGCCTTTACCCAAGCCTAGGGCTAGTTGAAATCCTAAAGCCTAACCCAAACCCTAAGCCGATAATTGCCTAAGCGTAAGTCCAACATACTTAGGCCTAAGCATTAAGCCTAACAAGCATGTCCCTTTTTCTGGCAATTTTAGGAATTTCTAGAAATTTCACATTTTCTCTTTTTCCAGCCCCTTCTAAACCTAGGCCTAGGCCGCATCAACCTGAGCCTACGCCTAAACCTAAGCCTAAGCCTAAGCCTAAGTCTAAGCCTAAGCAGCCTCAGCCTAAGCCTAAGCCTAAGTCTAAGCCTAAGCTTAAACCTGAGCCCAAGCCTAAGCCTAGGCCTAAGACTAAGCTTATGCCTGTTCCTAGCGAAGCCTTAACCCAAGCCTAGAAGGGGGCTAGTTGAAAGCCTAAGCCTAACCCAAAACCCTAAGCCTAAGCCTAAGCCTAAGTCTACGACTAAGCATATGTCTAAGCCTAAGTCTAAACCGAAGCCTAAGCCGAATCCCAAGCCTAAGCCTAAGCCTACGCCGACGGAGCACGAGGAGAAAGTACATAACTTTGTCACAAAAACAAACATTTCTCAATATCGGTCAGTTTTCAAAAATATTTCGGGTAATTTCTCAGGACAAATAACAAAAACCCACCCTTTCATACAAGTCCACAACTAGCTGTGTGCCAATTCTCCTTGTCTACCGGACTGAGCAACGAGAGGAACGATTGACAGAAGGCGAGTATTCTGACAAAATAAAAATGTGTGTGTGTGTGTGAAATGGCACGTCAGATTAAAGGGAAATAGAAAAAAAAAATTAAAACTGAAGGAACCTGCAGAGTTGATCCAAATTTCGGAAAAGGAGGGTCCGGCTCGACAAGAGTAGACATCCCTGTTCGACTTGACATCTCTTCAGCGTCCTTGTAAACATCGCGGAGCACGAAGAGCTGACGATAGAGGAAGACGAGCCGTGTGGAACAGCTCCCATAGCTTGAAGTTATGTGTGTCTGGATGTGGGAATTGTCGTGGTCTCGTCTCACATGAACATTTCCTCAAAGGATACTGGCTGAAAGTTGGATTTTTTTTTGGAATTGGAGCGCGTTTATGGGCTCGTTTTGCAGTTTGTTTATACCCTTAGACATTAAAAAGACATCAGCAACAAAGTCCCACAAGTAGTAAACAAGAGAGATTTTCTCTAACACGAAAATGTGAGAGAGGAATTTTTATTCGAAGCACCATGTTTCTCACTCAAATTTGACTACTCATAACTTAGGTAAACTTAATCCAATACTTCCTTAATAGCTAAAAATTCACATATTCCAACAAACTACAGTAAACTACAGGTACCCTACCGTACCCCTACAGTACCCCGACAGTACCCATACAGTACTTTGACAATATCACCAATCCACTCCCTACAAAATCATCAAAAACAAAAAATTCACAATTTTCAAACAGTAAGTACCCTAGAGTGATCCTATAGTATTCCTACAGTACCACTACATTACCTTGACATATCCCCCTAAACCAATTTCCACCCCCAGGAAGCAATACCCCTTCTAAAACTAAAATACCCATTTCCCAAAACTACAGTAACCCTACCGTACTAGTACCTGCAGTACCACTACAGTACCATTAACCTTGACATTATCCCCCTCAACTTCCAATTAAATACCACTTCAGAAGCTAAAAAATCAAATTTTCCCGAACTAAAGTATCCCTACCGTATAACTACAGTACCCTACAGTGCCACTACAGTACCTTGACATTATCCCCCTCCAACTTCCAACCCAATACTCAATCAAACGCTAAAAATTAACATTTTCCCAAACTACAGTAACCTTACCGTATTCCTACAGTACCCCTATAGTTTCACCTACCAACAACTTTTCCAGCTCATGATCCTCAATCTCATGATCCTTGAAGTCTCCAACGGCCTGAACATGCTTAAGAATCTCACTCCGTTTTGCTCGCTGCACCACTCGTAACGTCTCTTCAGTATCCAGGGCGATCGATTTTTCTGGGGCTGACACAAGCTACTGGATAGAAGGCTCGAAAGGCTATTGTGGCACGTCGGGTGAAGATCTGAAAATGAAGAATCGGTGGGGATCCGTGGTGTCAGCGAGGGAGAAGATCTATTTGGTGGGGTGGCATATAGAAGTGGGTAGTAGCGGTTTCTTCGTTTGTGTGATCTTTGTGTCAATAGACATGATATTAGGGCTTCGGTGGTAGGCAGGTGCGGTTTTAGGGCCTGGCTCTTGCCTGACGCCTGCCCTTCTCACGCCTGCCTGGCGCCTTTTATCATTTTGAGACAGTGAGTATAGGTTTCAAACTTCAAATTTTCTCATTTCTATCATTTTGTTGAAAATCAAATTAAGAAATGAAAAAAAAGTTTAAGTAGTTGCATTAGGCGTGTATTTAGGAATTGCGAGAGGCAGGCGGGGGTCGTCAAGTCAGGCAGGCAGGTCTTCTTATGCCTACACCTCCGGAAGGTGTTCAAAAATCGGTTGCGGGTGTCCAGCAGTAACTTGACAAGAATCATACAAAGCATTCGACTTTTACACAAACCTGACTAGGCTGTGTATTCCACCTGTACAAACACCTAACGATCGATGTACCTGATTTTATTTGATCTGAAAAAAAAATTTCTCAGAAAATTTGAATTCAAAATGTTTCTTTGAAAGTTTGAATTCCCTGCCAAAAACATTCTCAGAAAATTCAGGTTCGCCAAAATTGTTTCAGATTTGAAAATTTAAATTCCCGCCAAAATTTTTCTGTGAAAATTTGAACTCTCGCCAAAATGTTTTTTGTGAAGAAATTTGAATTCCGATACACAAATTTTTACAGAGCATTTGAATTTCCCCCTACAATTTTCACAGATCTTCTTATATATACATATATATATATATATATTAGTTGAACTTTTGGGCAGTTTTCAAAAAAAAAGTCCGGTGATTTATTTAAGCACGTGGTGGCAAAAAATAATTTTTCGGCTTGATCTACGCCGATCTACTAAAAATGCGGGAGACGCAGAGTTCTCAGTTGATTTCTCAAGGTTAAGAAAATTCCGGCATTTTGTACGATATCAAACCGTAATGGGACAGCCTGGCAGATTACCACGTGCTAAAGTTATAGTTAATTTACAAGTCCTGGTTGCAGTGGACCTGCAGGATGTCATGAAGTAGCACGTGTTTTCTGGAAAAAGTTGGTAAACTTTCATACGAAGAGGAAAGTGTAATCGATATTTACTTGACCATTTTTTTGCTAAAAAGTAAGAGTCTTTGAGCCAGGCCGGCGATCGGTAATTGCCGAAAATCGGCAATTTCGGCAATTGCCGGTTTAGTGCAAAGAATTTTTTGGCAATCGCCAATTGTGGCAATTGCCGAAATTGCCAAAAATTCGATTCCGCACACTCCTGCTTTGAACTGTGAATTTCCAAAATCCAATCGAAATTCTGCCGACACTGTACAATCCCTACCTGCCAACAATCCGCCGGAGCTGATTGCCCAAATTTATTGAGGTGACTCTCGTTAGGGGATAGATTTGATCATGTGGGACAATGAGGTCACATTGTCGAGCAGCACCCTTCGGATGAGGTCTCCTGATTCTCACTTGGCTGATCAGGAATGATTGCATGGCGTCGGGAAGGTTGCCTTATTAGGGTGACTTGTTTGGGCTCTCCTTCTTCTGGCTGGAAAAATACAATTTTTTGAAGTTAAGATTTGAAAAAGAAAGCTGTCATTTTTTTGTTGGTATTTTTTACCCTAAAAATGTGGTTTCAAAATATTTTTACATCTGAATATCTATTCAACGGGGTGAACAACTGCAGATCGACCATACTCGAGCTTCTAAAAGTTTGAAGGACGCTTCTCGTGAAGAAAAGAAAAGAAACACGATATAGTTACCCCTACATCGGAAGAGGATGGGATATACTGAGAAGTAAGAATAGGAAGAGAAATGAGAAGAGTTCATATGCACTAGAGAAGTATGTACAATATAATAATTTATGAGCATCTGAGAAAATGAGAGCTATTTGAAAATCTGCAGAGCAAGATAAAACTCGGTCTCTTATCAGAAAATTTGAAATCCCGCCAAAATGTTTATTGTTTAATTTGACGCCAAAACTTTTCACAACGAATTTGATTTCGCCAAAATTTTTCTCAGAGATTTTGAATTTTCCCGCCAAAAGATTTACCAGAAAATTAAAATTCCCGCCAAAACTCTTCACCTCGAATTTGAATAACCCGTTTTTTCTCAGACAGTTTGACCGCCAAAATTTTTCACATGAATTGAATCTTTCGCCAAAGATTAAAATCGTTGGATAATTTTCATTCGCGGCTGGTTTCCAAATCGAATTAAGAACGGCCAAAGTTTATCGGGGTTTTTTTTAACACTTACTACGAAAAAAAGCATGATATACATTTATTTTCCTAACGACGCCTGGTAAAATCCGCTTTACACATCAAAAACTTCTCGGCAACATTGCGTCACCGCCAAAAGAGATGCTTGCACTTCACCACGAATAATAGCTATGACAAGGCAATGCGTGTAGGGAGTTGAGAATTACAACTAATTCATATCCCCTGAAAAAATAAAAGCGCTGTTGTCTATATGATTCTTTACATGGTGACAGCTTACCGAAGAATAGACGGGTAATGAGATATATATGTGATTCATAAATATGGGCCTGCTCCCGGGTATCCGAGAGCCGAGTCGAAACAGAAGGGGAGCATGAATGGAGCAACTAGGGAAAATTGTGTTATCACGATGAGGCACGGCGGGGGACACAATAGATTTTTTTTTTGTCGAAAACGTTTTCCATTTTCACGTGGTTGGCGCATTACGATTTGAGCTACCAAAAACGCGGGAATTTTTCCCCTAAAAAAATGTATCGTCAGCACGTTGTTTACCATGAGAAATCAGTTGAGAAACTTGTTAGCGTCTCTTCTCCCGCATTTTTTGTAGCTCTAACTTGATCAAGCCGAAATGAGACGCTCTGACACCACGTGACGAAAAAAAGTAGATCAAAATTTGCCAAGCCCTTATAATACTCCCTTTTTCAGATCTAGGCGGAGCTCAGTTTGACTCTGATGACGTTAACGCAAATCTTGAAATTTCGAATTCTCTATGGAGATTAGAACTTCCCGCCCCCGCCAGACTTTGTAAAGTTCAACATAAAGATGAAATATAGAAAAAGTTCAGACTATGATAAGGAACTTATGACTAACGGCTCTTGAGGTGAATGAGTATGATGTGATTAGTGATGCAAGAGGTGCCGACTAGAGAGAGAGCTAGAGCGACGAGAGGCTCAGAGAGGGGGGAAACGGGAAGGTAGGTTTGTAGGTAGGCAAGGTAGGCAAATAGGGGGTCGGTATCCGAGAAATAAGGAACCTAGGTCGGCAGCCGTAGGCATAAAGTAGGTCAACATCCAAGTAAGTTAGACAGGTACGCAAAGATAGGAAGGTAAGTAGCCGCGGTGGCAAGGAGACTAAAGGAGTAGGACAGGAATACGTAGGCGCAGTAGGCAGACGATGAAGGTAGGTGGGTAAGCTTGTGAGAAGGCAGTCATAAAGAACGTCGACAGTAGATGCACTTAGTAGGTAGGTATGAAAAAAGAATTAAGGTATGCATAAGGAAGTAAAGTATGAATGGATGCAGCCGAACATGTAGATACAGAAATATCAGGCAAGTAGGAAACAGGCAGGCTCATAATATAGGAAAGTTAGCATCGTAGGCAAGTATGTAGTCCTGGGTAGGCATGTAGGTAGACACGTGGTAGGCTTATGGTTCGATATGCAAAAGAGCAAGCAATCATCAGAAATATGCATATTGGCAAGTATGTAGGCACGTGCATAAGATACAAAAGTAGACCAGGCATGTAAGTAGGCACGTAGGTAGGGAGGCTTGAGGCAGCAATGTAGGAGATCTGGTAAGTAGGTATGAGTATAAGTAACCTAGTGGTGGTAAGTCACAGGTATTTGGCACAATCCTGTGGTCACTGTTCTCAATGGTAATCAGGCGAACGTGCCTGCCTGCCTCCTTAGAAATTCGGTAAAAAGATTGTGGAAAAACAACTAGGGGAATTCCCATCCATGGAGTCCAATGCGTAATGTGAGTGGGAGGCGGCAAAAAAAAAGCGGACGTAAACACTTTTTCCTAATTCTCTTATACTCTCGCTCGTGGAAAATGTGAATATTTGATACAATTTTGTGGGAAAGTACAGCGAGCAGAAGAAGAAGCTGATGTCCCGATCGCGCGCGCGCGAAAAAAACTTTCAATTCCCACTCCCCTAATAATCCGCCTAACGCCTAATGTTTGTCAAATTCACCATGTATCGTTTTCTCACCCATCGGCTATGATTGTTTTTTTTTCTTTTTCAGCAAAAAAAACGGGCACATGAGGTCGGGATGGATAATTAGGGATGTGTGCCAATTTGGCTGATAGACAAAAAAGGAGTACGTGAGATTTTTAGAAAAGGTTGTTGAGAAAATTATCATGAGGCGTTGGGCACGTGGCCGCGAATGAGAAAACTAGGCTACCTTCACGGGGCCCCCATGGCCTTTCTCGTTGGAAAACTTTTCGCGATCTACTGACAAACGCCCGTGTTCCACACGGACAAATTCATTTAGTTTTGCAGCTAGAATCGATCAGCAACGCGACACGCAACGCGTCGACTAAATCTACCCCGAAGATATGGCCGCTCTTTAAAATGGCCTTGTTGGGCAAACTCTTCCATTTCAAATTTTTTATCGCCCTCAGTTTAATTTTTTAGGATACGCCTACGAGTGATCTAGGCCAGGCAGTAGGTAGGAGTGTAGGTAGCCCCCTTTTGGTGTCAGGCTGTCACATCGCGGTTTGATCTATCAAAAATATTGGTTCTCCCAGTAGAATGTGAAGTGAGCACGTTCTTAATCACGCGAAATCAGTTGATAAGTCTGCGTCTCAACCCGCTCCCGCATTTTTTGTAGATCAAGCGACGTAGATAAATACGAAATCAGACACTCTCGTGGTGGCAGAGCTGTCCCAACGCGGTTTGATCTACTAAAAACGCGGGAACATGTGCCCAAAATTATGAGACGTCAGCACGTTCTTAATCAGGGAAATCAGTTGAAAATAAAGTCTGCGTCTCTTCTCCCGCATTGTAGATCAAAGTAGACCACATTAAGACCTTCTGACACCATCCCCGAGAAGAGTTCAATATAACTTAGCTCGTAGAACATAAATTTTTCCACGTGGATTTTACAGCACAATTGCTTAGAGCCACTAGCGCGGTTGCCCAAATTTTACAGGAAAATGAATATTCAGGAAAATTTTACCAGATTTCCCGCGCAAGACACGAAAGTCTTAAAAAGTAGGAGAGCATGAAACTAAGAAAGTAAGAAACTTCTGGTTTACCACATAAATCAAATTGGAGATAGTCGACCTTAAAAATTTTGCACCAAACAGGGCGGAGCCAAAAACACCAAAAGTTACGCAAATTTGTACATGAAAACTAAACACCTAAAACCGGAGGACAAATATGAAGAAAAACGCTGAAAATGCGCAATGAGACTTTTTCCTCCGTTGCTTAATTTAATACATGTCCTCTCCCCCTTCCTTCCTGCTTTCACACTCTTTCGGCGTCGCCTCCTTTTGATTAGAGACCTGAGACTTTTTTTTTTGTGATTGCGTTGAGTAGTGTGGGATGCATATATTAAATCAAAAATCTGACATCAAAAATATCCCTGAAAAAAAACGTAGTTAAAATTTGCTTTAAAACTGCCGATGCGTTTGCTATTTGATCTACAGGGTGCTTTGGCGCGTTCGCGTCGCGGTTTGGAGTTCGAGGCGACGGCCATTCAATTTGACCCTACTACAATAGAAATATTTTGTAATCTTAGGCCATCAAAAATTTTTAAAAAACAAAACCGGAAATTTCTAGGCCATCAAGAATCTCTAGGCCACATCAGACTACTTTGAAAATTTGTAGGCCACAATGGGAACTATTTTCTGAACCAAATTTCTGAAATTTCTTGGCCACGATCTGAAATTTCGAAGCCATATAAAGATTTGTTTATAGGCCACGATCTGAAATGCGGATTCTAGACTACATCAACAAATCCTAGGCCACGATACTAGGCCACTATTTGAAATTTGTAGGTCAAGGTTTGAAATTTCTAAGCCACGATTAGAAATTTCTAGGCCACGATCTGAAATTTTTAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAAATTTATTAGGCCACGATCTGAAGTTTTGGTCATCAAAATTTCTAGGCCATTTGAAATTTCTAGGCCACGATCTGAAATTTGCCACGGTTTGAAATTTCTAGGCCACGCTTTGAAATTTTTAGGCCACAATCTATTTCTAGGCCATCAAAAATTCATAGGCCACGATTTGAAATTTCTATCTGGCCACGATTTGAAATTCTGGGCCACGAACTGAAATTTCTAGGTCATCAAAAATTTCTTTTAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAAATTTCTAGGCCGCGATCTGAAATTTCTAAGCCATCAAAAATTTCTAGGCCACGATTTGAAATTTCTAGGCCGCGATCTGAAATTTCTAAGCCATCAAAAATTTCTTTAGGCCACATTTTAAATTTATTGTTTAAAATTATAGGTTTTCAAAAAAATTCTAGGCCATCAAAACTTTCTGCAGGGATTTGAAATTTCTAGTAGCCACGATCTGAAATTTCTAGGCCACGATTTGAATTTTCTAGGCCACGATTTGAAATTTTTAGACCACGATCTGAAATTTCTAGGCCCTCCAAAATTTATAGGCCACGATTTGAAATTTCCAGGCCCCGATTTGGAATTTCTGGGCCACGATCTGAACTGATTTCTAGTCATAAAAATTTCTAGGCCACGGATTTGACATTTCTAGGCCACGATTTGAAGTTTCTGGGCCGCTAAATTTCTAAGCCATCAAAAATTTCTAGGCCACGTTTTAAACTTTTTAAAATGTTTAAAATTGTTGGTTTTCAAAAAAATTCTAGGCCATCAAAAATTTCTAGGCCACGATTTGAAATTTCTAGGCCCCGAATCTTTCTAGACGATTTGAAATTTCTAGGCCACGATTTGAAATTTTTAGGCCACGATCCGAAATTTCTCCAAGGCCATCAATTTATTGGCCACGATTTGAAATTTCTGATCGAGGCCACGATTGAAATTTTTAGGCCACGATATGTAATTTTTAGGTCCTCAAAAATTTATAGGCCACGATTTGAAATTTCTAGACCACGATTTGAAATTTCTAGGCCACGATTTGAAATTTCTGGGCCACGATCTGATTTAGGTCATCAAAAATTTCTAGGCCACGATTTGTAATTTCTAGGATTTGAAATTTCTAGGCCGCGATCAGAAATTTCTAAGCCATCAAAATTTCTAGGCGGCCCACGTTTTAAAATTTTTATTCAAAACATTTATAGGTTTACTTCAAAAAAATTCCTTAGACGGCCATCAAAAATTTCTAGGCCTACGATTTGAAATTTCTAGGGTGACAACGATTTGAAATTTTAAAGCCACGATCTGAAATTTCTAGGCCATTAAATTTATAAGCAGGCCACGATTTGAAATTTCTAGGGCACGATTTGAAATTTCTGGGCCACGAAAGATTTATAGGTCATCAAAAATTTCTAGGACAGGATTTGAGAATTGCTAGTCCAGGATTTACAACGAAATTTCTAGTCCGCGTATTATCAGTCGAAATTTCTAAGCCATCAAAAATTTCAGGCTCACGATTTGCGCGAAATGTCTAGGCCACGATCTATTTGAAATTCCGTGTTTAGGCGATTTCAAATTTCTTGGCCACGATTTGAAATCTAATTTATAGCCCGTGATTTGTAAGTTCTAGGTCATCAAAAGGCGATTTCTAGGCCAGGATTACTCTAAAATTTCTAGTCCATCAATATTTCTAGCACAAAATTTGTGTTCACTTTTTTTTTTGTTTTGGTATGTATTTTTCAGAACTTATTCAAAATTTGTGGGAGCAACAATATGCTTTTTTAATTTCTACGCCACAAAATTCTTTGGCCTTTTTCACTTTTTTTCACGCCGCCTATGGTTCCACTGGATAATTGAATGTAGAGAAAAAAGGGAAGGGTTCAGCTAGCGCAAAATAATTCGTTGGAAGGGAAAAAAATAAATGCAAATCTTCGCCAAAAACCAATTTTAGGTCGGAGCTCGGCGCGGGTTCGCACACACACAAAAATGGAGCAGAAGATGACGTCAGATCTTCTTTTTCAGAAGGCTTTCTCAAACTTTGAAAATGGCCAATTTCTTGCTGCTAATTGTGGGATGGGGACAGAATGATATTTTGTTTCAGGTTTCACACCACATCAGATCCTAGTCTTATTTTTTTCTTTTCTCAGGAGTACACACACTATAAATTGTGGTAAAAAAAAGAACACGTCCAGACTTGCTTATTTTATACCGATTTGATGCGGCCTACACAAAACGCGGGAGTTAAAAAGCAACTCGACATCTCACCTGATTTCGCAAGAGCGTGCTCTAGACCAACCGCCACAATTTTTTTGGAAAAATATTTCCGCATTTCTTGTAGATCAAACTTAAGACACCCGCACCGCGTCACAAATAGTATTCCTCTTGAAAAGGATTTCCCAATCAAGTTCCTTGACAGGCGTACGCAAGATTTTGCAAAAAAAATCGGTGGCCGAGTTTACTCTTCTGGCGGCCACGTAACAAAATTAACAAGGAACGTATAAAAAGGAAAAAAAAATTTTCGTAAAAAGGTACCAGGGACCGAAGCAATTTGAGGAAGGAAGGAAATTTGAGTGTCACTCAAATGATCTACCGGTTTTAAGTCGGTGGCCGCGGAACAGAGAAAGCTCGGCCCCCAAGTATTTTTTAAAATATCACGGATTTCTGGTCCCTGATAAGTTTGAAATGGAAGAGTAAAGAACGAACTAGGCTAGCTCGTCTGGGGCAGATTCACGGCGTTGCGTGTCGCGTTGCGGCTCGATTTTAGTTGTAAAATTAAATATAATTGTCCGTGTGGAGTACACGACTTTCCCACGAGTTTTCCGACCGGCGATTGTCAAGGCCCGAGCGCGAAAAATTCAATAAGGAACGGCCAGCCGTGAGATAGGATTTAAAAAATATTACACAACTATTTATTCAAAACTGGCAATTATACATACGATAAGTATTAACTACATACATGGCCGCGAAAAACCCGGCCACCAATTTTCGCGGTTCACTTACCGGATCTCCTCCTGAAATCAGTCTTGCCCTATAAAATAAGGGCATTTTTCGGATCATAGTGAATGAATTATTTAAGGAATATTATTTTAAAGAACACACACCACACAAGACATGTGAAGGGAAGGAACCAGGGAAAAAGAGACAGGGCAAAATACAATTTCTCTATTATTCCGCTCTGTGTTCTGACTAGCAAATGCAGAATCAGTGATGAAGAAACTGGGAATTTACGAGGTATTTAGCGAGATGGTGACCGCGAGGATGAGGAAAAAATCGGCCACCGCAAGACTTACCGGCTTAATCAATTGACCTGGGCCCGTATGTGATGGAACAATCATGTGAGAGCCGGAGCTTCACTCGTCATAGCTTTGTGTCTAGGTGGCTCTCAAGTACTGCTGGAGCTGAAAAACTGTAAATTTAATTTGAAATTTGTTTCGGATGCAAAAAAGTAGCGACACCTGCCGGGTTCCCACAAGATGTCGTTGAATTGACCTAGTAGAATCGTTAGTGATCTACCGAGCAAACAAGTATGCTTGCAATAAAAAAAGGCGTGTGGTTCAAGGTCGTTGACAAATTCGACACTTTGGACACACGAAATTGGTTATGAGCCACACCCCGGCTAGCTTAGGTCAGGAGAAGAGCCTCTCCGAAGAGGACCCCATGTGCGCGCGCGAGCCGAGATTCTGACAACATGAGAAGCGGAGAAGGCGTAAAGGGAGAAGAGTCTAAGTTGAGCTTGTTGCTGAAAATATCTAGGACTCAGGCTTAAGCTTGGGCTCAAGGCCTCATGCTCAGGCTTAGGCGGATCAGGCTTAGGCTCAGGTTACCCATAGGCTCAGGCTGCTCAGGCTTAGGCTCAGGCTTGGAGAGGCTAGCTCGGAATTGGGCTTCGGCTGCGGCCTTGGCTTGGATTAAGCTTAGGCTTAGGCTCAGCCTTAGAATTGGGCTTAGGTTCCTGAGGCTTAGAATTGGGCTTAAGCTCAGGCTTAGAATTGGAGGCTTAGGCTTTGGCGTAGGCTCAGGCTTAAGCTCAGTTAGGCTCCGTTGGCTTAGGCTTAGGCGTTTAGATTTAGAGGCTTAGGCCCTGGCCTAGGCACAGGCCAAGAGGTCACGCCTATCACTTGCTCCTAGATGTGGTTGGGGAAATGAAATTCTAGTGACGTCAAGATTCTGGAAGAGTTCCGTTGACGCCACCAAAAGCAACAAACACTTCAAATCTGAGAAGATCAGGGCGGAACAAAATGTACTGAAAGTACAAAAAGCCCGCATTTTTTTCTCTAATAATACTACATATCATTTGAGTGGGGTTGAAAAAAATGTGTTGCAAGAACTTATTCGGGGCGAAAAAAGATTGAGAGGAAAGAGGAACTTGTTTTTTTGTTGGAAAATCGTAGGTGTGACGTCACTTCTCTTCCAACGCCCAGGTTTCTAGGCAACTTAGGACATTGTGCAAAAAAATCACAGAGCAAAACTACAAAACCCCAGGAAAGAAATGTGCTCTTGGCCAAAATAATAAATATTGGTTACGAAATAAAGGAGAAAGAGAACGAAAAAAAGCTTTAAAAAAGAAATCAAGGAGGAATGTGGAGAAGAGCTTGTGAGGATATACCCAGCAATTAGGGAGAGAGTACTACGCTGTCGGGAGATGACGTTTCGAGGATATTTCTAAATTCACTGGAATGAAGGGTGGTGGAAGAGTTTTGTAAAGTTCGGGTATAGGCCAGGGGTTTTTTTGGCCAATGAGCCTGGTGCATCGAAGAAAAGCTACATTGGAAGGTTTTATGTCTCGGCCACAATAAATTATAAAACCTAGTACGATGAAGCACACTTGCATTAGGATTGCAAAAATTTATTTGACAATTGAGAAGAAAGAAAATCAGGGGGGCATAAATGCGCCATAGAACAGTGCGATCAAATTGTAGAAGAACTTTCGCCCAAAAAGCTAGGCCACGTAGGAGACCGCTGGAGAAAGTACGTGTATATGGTGGAAGAGTTTTCTTGTTTTTCTAGGCAATCTTGCGACAAAACTTGAATTTATGAAAAGATGGCTTGGAAGAGCTTTCGCATAGAAAATCTAGGCCACGGCTAGCAATTTAATAGGAGATAGAAAACCGCGTCGGAAGATTATTTAACTTTTCCATAAAAATTAGCAAATGTAAGAGAGTTCAGATACTGATCTGGAAGAGTTTTTGTGCAAAAAACCTTGGCCGCGACCAGCAACTAAAGTAGTAGGGGAGATAGGGTACCCCGCTAATTTTTTATTTATTTTTCAAAGAAAAAGTTTTAAGGCTTCGGGATTTGATGAAATGGCTCGGAAGAGCTTTTGCCGAAAAACTTAGGCCACGGCCAGCAATCTAATGAGAGGGGGAGGGTTCCCCGTTAAATTTTTTTTGTTTTTTAAACAAAGTTTTGGGGGGATTTGATTAATTGAGCACCATGGAAGAGTTGTTAAGCAAAAAAACCTAGGCCACAGCACCCTGAGAGGCGGGACCATAAGGTAACCCTACGCTATATTTTTTTTTTCAAAGAAAGTTTTAAGGTTTTGGAGGAAATTTGATTACATTACTTGGAAGAGCTTTTGCAAAAAAAAACTTAGGCCACGGCCAGCAACCTAACTCAGAGTAGAATGGGAGATAGGGTACCCCGCGGAAAATTTTTAGCGTTAATTTTGGTAAACAACAATGGAAGAATTTTCCGGTTTTCTAATCCATCGCATTTTCAGCGTCACGGATTCTGTGGCTTCCCCTCGCATAAAATGGAAGAAGTTGCCGACCTATATCTGGGGTAGATTTACAGTGCGTTGCGATGTCGAGTCCGCCGCTCGAATTTAGTTACAAAACTAGGTAATGTAATTATTTGTCCGTGTGGAGTACACGACTTTCCCAGGAAGGTGATTGTCAATGAAGCGCCAAAAATTCTCAACCAAAAGAATCCAGATTCCCGCGCAGCATCGCCTAGGAGAACATTTTCAAGAAATCTGGCTCACGAAGGATTAAGTAAAACAAGAAAAGAAATAAAACTCTAAGATGAAAGGTAAGGGTGGATGCGGGACAACTTATCACTATTTGCCATCATCATCATTTTTCTTCTCCTCCTCATCAGCTTCTGCTCCTCCGCGATCTCGCGGTGACTCTTCTGAAATTCTTAACTAGGCCAACACAACGTCGGCAACGAGTTTCGAACCCTTCACCCACAAACACATACGAAAAAAGCTCCTTAATTGGAGCAGGGAGACGGAAGAGGCGAGGGAGGAGAGGCTGGTCAATGAGTTAGAGTAGAGAGAGAGAGAGAGAGACTGAAAGATGAAGTATAAGCAGAAGTCGTCGGGATGACAGAAGTAGGAGGAGAAGAAAACGTGAGAGGTGGAGTCAGAAGGATATAATATATTACATTCATAGCGAGGATTACAGTTTAACGAGGCAAAACAAACGAATGCTCCAATATGAATTTTTGGGGTTACTGTAGTTTTTTCTGTAGCCTTATACTTCCAGAAGTTACATGATAAACATATGCGAGTTTTTTAAAATTTGCCAGAAGCACGGGTTCATTTTTTTCAGGCTCAATTGACAATCGCCTGCCGGACAACCCACGTGGAAAGTCGTTCCGCACGGACAAATACATTTAATTTTACAACTAAAATCGGCGACACGCAACGCGTCGTAAATCTACATATATGGCCGAGCCAAAATGACCGACTAGTTTGGCAAAGACTCTTCCATTTCAATTTATGATGGAAGCCAGAAATCCGTGCAGAAGTTTCTCGGAAAAAATACAGAAAGTTTGTGAAAGGGTTGCGACCTCTAACGGTCTTCATTAACATAAATTCAAATTTGACGCGCAATAATGAATTGCGAAATTTACTAGCGAAACATGGTGCATTGGGTGTTTGAACCACAATTTTACAGATCTGTGGTCACTAACATCAATGCATGGCCCGAAGGGAAGTGGTACCTGTACGCAATTTATCTAACGTAAACCTGGACGTTTGGGCGCGTGTATCTCACAAACGGTTGGTCCTGTTTTTTTGTGATGCATTTAAAAAATTTGAATTAAATTCTAAATTTATTGGACCAATGCTTTTTTCGTTGAGTATCACGCGCCCAGACCTGGTCTACACTCAAATTACCAGTAGAGCGCATTTGCTGACCACTTGCTGTCCGGGCCGTGTTCAATGCAACGATGGCGCGTCAAATCGACTGCAACTTCAGAAATCCCTAGTAGTTGCGCTTCAAATTTGATGCATTGCACGGCCCGGCAAGTGGTACATCTATGCAAATTCGCTCTACTGATAATTCAGTGAAGACCAGGTTTGGGCGCGTGATAACGAAAAAAGCTTTGGTCCAATAAATTTACTTAGAATTTAATTTCGTACATTTTTTATATGCATCACACCAAGAAAAAACTGGACCAACCGTTTTTACACGCGCCCAAACGTCCAGGTATACGGTAGACAACTTGCGTACAGGTACCACTTCTCGGGCCGTGTTGAATGTTTGAGTTAAAATTTTGAGTTATATGTGCTGGAAAATTGACATGAACATGGTATTTTTCATTATTTGCGCGTGATGGTGCATTGAAGTCGTTTGCAAATTTTTTTCAGAGCTGAGGTCAACTGACACCAAAGCAACAGAGTTGACGATTTTAAACTGCACTTTTGCACGCTTTGCAGTCGGTATTTGGAGGTTATTTTCGATTGTTGTGTGAGATTCACCGACACACCAGATTGGATGACGCGCAAAATTGTACGAAAACAGTTAGTTAGAAAACTAATAAAAGAAAACTATTAATAAAAGTATAGCGAACATCCTGAACAATTATTTCTGCACCGCCAATGTATCTATAGCATGAATTTCAAAATATACAAAAAAAAATTATGAAAACCACGACGAAAAACCCGGAAGTGTTTTTTGGGTAGCCTGTCTGGATTCCTGAGGGTATTGAATTTCGCCCTCGAATAATATTGTTTCCTTTTTCCCCAGAATACCTACAGAATTTGGGGGAAAGAAATGAACTGTTCCTCACATTAACCTACACGTTCTTATTTTTAATTAAATTTAGGCCACGCCCAGAAAGTAGCTGGGCGGGGTTGCACATTTTTCTAGCTTTCCAAAATATAAAAAGTCGGAAAAAAAGTTGTAGTCCGTAGTTTGTAGTTTGTAGTTTGTATCAGCTTGTCCCATAAGTTTTTGTACTTTTTTTCAACTATGTTTCCAACGTCTAGAAAGTTTTAAAATTTTTTCATCGTAGGTCGTGTCAAGCGGGTCGTCCCGGGCCTGTCACAAAAGATTCATTTCATCCATTTCTACTTTGCCACGATGACAATCATCAAACCTGAACGTCGAGACGTTAGATTGCTTCTTCTTTATGAATTTCGTCTTACTTAGGTCATTCAGCAATGGAAGCGGAACGAAACATATGCGGTCCGATGGGTGAGGGAGCACTCTCTTATAATACAGCACTCAAGAGTTTCAAAAGCTCAAGACGGCGCCGACTTCAGTCTCGAGAAATAGAACGTCAATGTGGGCGACCGGAGGCTACAGTTAAATGAGGAAGACATAGGGAAGCTGGTGGAAGCGCCTCGTCTTAGTCTTCGTGAAATGAAAGAGAACCTTGAGTGTTGTCACAATAGCAAAATTGCACGTCACTTGGGTCGCCTTGGTTTTACTTCAAAATTTGGAAGCCTGGGTGCCTCATGAACTTTCGGCATCACAGAAGCTCACTCGGGTCACCGATTGTACTCATAGACTTCTACCTTTTCGTCGGTACGATTGGCTGAACGACCAATCTTTACGGGAGATGAGAAGTGGGTGCTCTATGTTAACCCACGAAAACGTCTATGGCCGATCGGTGAGAAAGGAATAGCGACGCCAAATGATCTTCACCCAAATTATGATCTGTATCTGGTGGGCTGTTCAAGGACCCGTGCACTGGGAATTGTTGCCCACTAATAAAACTATCACTGCTGATTCCCTGACTATTGTGCCCAGACCGAGTTGCAAAAGACCAACGGAAAATATGAAAAACTATATTTTCCAGCTTTCACGATAATGCTAGTCCTCATGTCGCCAAGAAGACTTTGCAAAAGCTGCAAGATCTTGGTTGGACTGTTTTACCGCATCCACGATATTCTCCACATCTTGCACCAACGCGTCAAACTACCAGTTCTTGTCTCTCAGTGACTACTTGCGCGACTAGCAAAGTTATTCGACGACGAAGAGCATCTCAACTGAACTCTCCACTTTCTTCTCATCGCGCTCGGTACGCATTTCTTCTCCCGTGGCAACATGATGTTACCTAGTAAATGGCAACAATTTGAGGTGGAAAGGTGAATACTTGTGTGTATAGTACTACTTGTCGCTTGAGAGAAATAAATTTTTTTTCAAAAAAAAAATAGTAGAAAAACTCATGGGACAACCTGATAGTTTTAGTTCGTTATTTGCTAATTGTTAACGTTAGTATTCGCCCAGGAGGGCCGAAATAAATAAATTTTAGAAAAGAAAACGAAATTATATACATAGTCATTAAAATGTGGTAGTTTGTAGTTTGTAGTCGATGTATTATGTCTATTCAAATTGTATTATAAACAACATCTAAAATTAAACAGGAAACTTATATTTAAAAAGAAAACGAATACTGAAAAAAGGCGGCTGCATAGTAAAAAATAATGATTCTCCTCCAAAAAATGGAATTCCATTTTTTCAGCGGCTATTTTCACGATGATGAGAGGAGACCAACAAAAACATTTGAGATGAGAAATGAGGGGAATCTTGCACAATTGAAAATGGGAAGTGATTTTTTTAACTTTATACACAGTTAAAATTCCAGCGAAGATCTGCGCGCAGAGTGTTTTTGGCGTGGATCGCGAGAGAAAAAGGAACCGGAGGTGCGCACAGCATTGTGCGTCCATCGCGAATTCTTTGAGATGCATTAGAGTGCGAGCATCGCGAACATAAATAATGGGCACATGTGGTTTCTCCTTTCTGATGATATTTTACTCTCTATGGCTTCTCCAATTATCTTTATCTTGTACTCTGTGCGCTGCCTACTATATTCTACTCTCAGTGTCACCAGTCATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCCTACTATATTTTACTCTCTTTGGCTTTACCAATTATTACTGTGGCTTCCCACTATATTTTACTCACTATGGCTTCCCACTATATTTTACTGTCTGTGGCTTCCCACTATATTTTACCCTCTGTGGCTAGTCCCCACTATATTTTACTCTCTGTGGCTTCCCACTATATTAGATTTACTCCTGTGGCGTCATCAACTATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCACTAAAAATGTTTTACTCTCTGTGGCTTCACCAACTATTTTACTCTCTGTGGTTTCCCACTATATTTTACTCTCTGTGGCGCTACCCTCTATATCTTACTCTCTGTGGCTTCACTAACTATTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACTATATTTTACCCTCTGTGGCTTCCCACTACATATTACTCTCTGTGGCCAACTATTTTACTCTCTGTGACTTCCCACTATATTTTACTCTCTCTGGCTTCCCACTATATATTGGTTAATATCTGTTACTGGTCACCATTCTCGTCGCTTCCCACTATATTTTCCCTCTGTGGCTTCACCATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACTAAATTACTCTCTGTGGCTACACCCACTATTTTACTCTATGTGGCTTCCCACTATATTTTACTCTGTGGCTTCCCACTTTCATATTTTACTCTCTGTGGCTTTTTCCACTATATTTTCCTCTCTGTGGCATCACCAACTATTTTACTAACTCGGTGGCTTCCCACTATTTGACTCCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCACCAACTACCGGTTTTTACTCTCTGTGGCTTCCCACTATATTTTTATCCTCTCAGTGGGTTCCCATAGCTCTACTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTTGGTGGCTACACCAACTATTTACATAACTCTCTGTGGCTGCCCACGCTGTATATTTTACTCTCTGTGGGCTTCCCACTATATCTTACTCTCTGTGGCTTCACTAACTATTTTACTCTCTGTGGCTTCCCAATATATTTTACTCTCTGTGGATTCCCACTATAACGATTTTACTCTCCTGCCTACAATATTTTGTCTGTGGCATTCCCTCTATATTTTACTCTTGGCTTCACAGTGTATTTTATTCTCTGGCATCACAATTATTATATTATACTCTTTGTCTTCTCGCAGAAAGGATATTTTACACTCTGGCTTCACAGAATATTTTACTCTCTGGCTTCGCAGAATATTTTACTCTCTGGTTTCGCAGAATATTTTACTCTTTTTCGCTATGTTTCACAGAATATTTTACTATCTATTAATCCAATTCTTCGTATAACAATCTATTTTTTCGTATTAACAATCTATTTTTTGTATAACCAACTAAACTCGACTTTTCCAAAATTACAGGAACCCTAAGAAATTCTACAGGACTCCTAACTCGCAACCTGCAGTTCAATGAATCACCTCGTTTTTTCACGCGTGACTCATGACTTCCACATTAGTTTACATTTCCTTCATCCATCGGTGTTGGGGCGCTGTTAATATACAACAATTAGAAGAGACCCCACCTCACGCTGCTATTTCTGCTGCTGATCTGTCAAGAATTCTTACCGCCACTTATGACTCATGCCATCAATGACTACTTCCTTCTTTTTTATATTTTCGGCTTCATCTCGAGTAGCAAATTTAACAAAATTCAATAGGTGTGACGTCATCACACCTTCCAGTGGAGAAATCCAAGATTTCTCTCGAAAGGATCAATGTGGTGTCATGGCCAAAACTCCAGTGTGAAACCTAGGCTATGTTAAATATTGAAACCGACTCTAAACTGAGCACATAAGGCTATGATGTCATGGCCTAGAAATCCCAGATTCTATGACGTCATGAAAGACCTGAACTGCACCGAACCTACGAATACCGTCAAAAGGGGTCCTGCTGTGAAGTCTTGTTCGAGAAAACAACTGAGTGCGAAAACTACGGCTCTCCGTAATCTACCATGTGGTAGATCATGCGGCCCTATTGATGGTAGAAAACTTACAGCTTGAAGCTATGTCTTACCTAGAAACTCAATAGTTTTGACGTCATCAATGGCCTAGGTGTATTCGAATGACGCAGTGTCTTAGAATTTTCTGAATATCACACAAAAGTATAACATCTTCTTGAAACCAAATAATTTTGAGGGAATTTGTAACACCCACCCAGTATTGTAACAAATGATATAATAGCGATCGGAACATTCGAGAAAACTGGAAATTTGAGACCTTGTTCGGGAAACTTACCAGTGATTATGCCCAGAGGATGGCTGTGTCGAAAAATGTGCCTAGGAAATGGGATTAGAAAACACGCTTCTTCCTTTTTTTTTCTAAGTACAGAATTACGTTGATAACGAGAAGTGCATTTCATTTTTGTTAGGTTGGAAATTTGAAATTTAAATATTCGTCTCTAGTTAGCACAGCCGTGGAAGACTTTTTCAGAAACGAAACTTTAGCCACGTGTCGCTGGCGGTGCCCACGATATTAGAGAATGTTGATATTTCCTATTTACTTATCTGTGATCATCGAAATTTTAAGATAAAGTTACTACCGTTCAGTTACACTGGTGGAAGAGTTTTTAAGATTTCCCACCGCACAGTTTGGGTGTGCCAGTGACCCTAACACTAAATTTGTAAAATTCTTTTTTCAGCCAAATAATCATATGGTGGTGTCGCCTAGAACCAGAAATTTAACACCTGAAAACTCTTCCATATTTTTTTAATTTCTGAAATCCAACGAAAAATAATTTTCAAACTCCTCTTCCTTCGAATGTTCCAGAAAAATAAAATAATGTGACGAAATCAAGTTCATCTATGAGTTGTGTGGAAGAGTTCAGATTCCTAGGCGACGTCAAAGTTTGAGGGCCCGTGACCCTATCTCGAGACTAAATTTTCCAATTTTTTCAGCCAACCCCAATCAGAAGCTTTCTCTGGCCTGTAATGACATGACAATCGGATATTATCATATGAAGTTTTTTAGGTTAAATTTCTGAGGTCATTTGCAAAGGTGTCATGACTATCATAGTTTGGAGGCTTTTTTGTAACGGTAGGGGTATGAAACTTGTTACTTCTCGAAACGGTATTATGTGGGGGAGAGGAGAAGGAAAGAAGGAAGGTTAGCCAACAGAGATAAAGCAAATTTTGTGTTAGTGGTGGCAGTTTTGAAAGAAGCCATGCTCCAAGGTCGGTTTGTCTTCTTCATTTTTCGGTTTTCTTTTTTGTAATGATTAAAAATATTTTTGTATAGAAATAAAAATTCAATACCAAAAAAATAATCACTGGAAGTTTCAACGTATCGTTTGACGCCTTCAAACATTTTTTAAAAATTCACAGTTTTTCAAATAGATGTACGTACACGTGGTGTCAGAGTATCTCACTTAGTTTCGGCTTGACTACACTTCAAAAAATGCGGGAATCTCCAAAAAAATGTGGAAGTACAGCACGCTCTTATGACCATGCGAAATCTTGAGAACTCTGCGTCTCTCCTCCCGCATTTTCTGTAGATCAGCGTAGATGAAGCCGAAACGAGATACTCTGGCACCATTTTATTTGTTTAGGGCAAAAAATTCCCGCATTTTTTGTAAAGGGATCAACCCGTAATGGGGCGGCCTAGCCCCAGTTTGCGTGCATACTTATTCCTGATGCCGAACGACATTCGCCGATATCCCGTTTTTACAGTATGACTCCCAGTGGGTTACTGTACCAGATTTTTGGTGCTTTTATAATATTGTTTTCTTTTTCAAAAATCTATGACGGAAAAATTTGTACAATTGTTTTTTTTTAATATTTGAATTTTTTCGGCTCCCAGACATTTTAGCGGGATATCGGAGTATCGGCGCATGTAAACGTTTTTTTTTTGGTTTTTTATATTAAAAACGGTTAAGTGTCGTAATAAGACGTGATTCATTTGAATAAAAAATAGCGAGCGACGCCGGCCACCACGACTTAATGGCTTCCCGTCCTAATAACAAAATGGAAGAGTTTTTGCTCCGAACTAGGCCATTTTGGCTCGGCCGTATCCGGGGTACGATTTACGGCGCGTTGCGTGCCGCATCGCGGCTCGTCATTTTAGTTGTAAAACCTAATGTATATGTTGTCCGTGTGGAGTACACGATTTCCACGCGGCGGTTGTCCGGAGGCGATCAATGGCGCGCAAAAAATTATGCCTAGGACAGGACACCGATTCAAAGATATAACGGCCCACATTTCAACAGCGGTATATCGCGAGGGAGTGTCGTTAAGCCTGCACACGGGTTTCTGGCCTTTTCATTGCTTTTGCGCGCTCCATTGACAATCGCCTGCCGGGCAACGCGTGGGAATCGTGTAATACACACGGACAAATTTTTTTAAGTTTTATAATGAAAACCGCGACACGACATGCAATGCGCCGTAAGTCTACCCGGGCCGACCGACACGTGGTGTCGGAGTGTCACGGCTTGATCTACGTAGACCTACAAAGAATTTTGCGTGATTAAGGACTAGTGAGGTGAAGTCACACAACTCTTATGGGCAAAAAATTCCCGCATAATTGTAGATCAAACCGTAAAGGGACAGTCAAAATGGCCTAATTCGCTCTTACATTTCAAAATATAATGGTAGGCAAAAGCATGATGGGGAATTTGTGATTAGATTTTTGAAAAAGGAAATACAATTTTTTCCAAATTTCTACTGAAATTTTTAAAAAAAATGTATTTTTTCCCTAAAATCTTCAAATTTCTGGGGTAGTTTCAATCTCTCACTACCGTGGTAACCAAAAATATGTTTCCTATTTTGACCTCCCGCCACACAGTTTTACTAACAACTTCTTCCCCCCCCACCCACCCACTTACTTCGTATCTGAAACTCCGCCCCATTTTTCGTGTACTTTACACTTGAATGGTGATGAGGTAGAACAAATCTGTGTTTATTGGAAGATCAGCAGTGGTAGCAACAGGAGAAGAAGAAGAATCAGCACTGTGTGGAACCAGCCAGCTGTGTTGTTGTGGTTTTAGTCCTGGGGCTAAGGGAAGAGAGAGGACGACGTCGTGTGTCTTCAATAAAATGAGGATCTGCTCCTATTCCTGACTTTCTTGGCTGGAATTGTTCAGGTAAGCCGGGGTTTAAGTATTGATATTGGTGCTATTTGAAAATTATTTCAAAAATTTTCGATTGGAAAATTTTTTTTTTTTGGCCCAAAACTTTCTTCTAGAACTTTATCATTCCTAGGCATACTAAATATGTCTGCAAATATTATTTTTTCTGGAAAAACACTTTTGAAAATGTACATATGGATAGCAAGTTTGGTTTTAGTATTATTTTGAAAAATTATATTTTTTCAAAAAAATTTTTTACAAATCTAGCAAGAAACGATTTTAAAAACAATTTTAGTCCATTTTCTTTTTTGTTTTTTGGAAATTTCACGAAATATCGGCCCAAAATCAATGCAATACTATTTTTTCACAAAGAAATTTTCAAAATTTGACAATATACAGATCTAGGGCTTCCATGTTAGGCAGGCGCGGTTGCAGACGGCTGCCTGAAACCTGCCTGGTTGCCGCCCGCCTTAATTTTTACGGGAATTTAGAAAAATTTCTAATTTTCTCATTTCTATCAATTTGATTAAAACCAAAATAAATTGCCGAAGCCAAAGGTTGCCTTAAAGACAGGCAGGTGGGCGTTTTAACGCCGAGCAGCTTTACAAAAGCACTATACAACTCTGTTTTTGAAATCTAGCAAATCTTTAAATCAATAAGAGACATGGTGGACAAGACAAAGACATCGACAAATTTTCGACAATATCATCTATAATTTTTTTCGGAAAAATTTTAGTTTATACCTTCCAAATTCGCCAAAGTGAAAAAAAAGTTCCTAAACGTGAGATATTGTATGTCTTCTACACATACTAGCCAATATCAATAACATCTGCCAAGAAAATCTCGAACCAAACACCAAAACGCGGCGTTTGGTAACCGGTTTTCTCTTTTCCAAAAAAACTATACATAGTTTCTAGTAAACAAATACAAATGGAAAATTCAAGGTGACAGCGAAGAAAAAAAGAAAAAAAATAGTTGGTAGTCGCCTAAGAATTGCATGTAACGTCACACCTCGGCCTTAAGAGGGGTCATGGTACATGCTAGATGATTAACCATGGCAAAAGAGTGACGGACCTTCTCGGCCATGACAGTTTTTAGGTTTAGGCTTATTTAGGCTAAGGCTTCGGCTTAGGGTCGTAGGCTTAGGCTTAGGCTTAGACTTAGTCGTGCTCAAGCTTGAGCCTTCTTACACTGGCGTAGGCTTATCCTATGAGCCCATAATCTGAAAACAAATATTAAAAAAAAACCAAAAAAAAAAAAAAAAAAAAACAAACAAACAAATAAAAACAAACAAACAAAAAACAAACAAAATATTTGAATTTTTCTAAGAAGACAAATACGTTACTATCGGTCACGATTTTTGGGCTTTAGGTTTAGGTAGATGTTTAGGCTTAGGCTTTGGCTTAGCCTTAAGCTTAAGCTTAGGCTTAGTGCTTAGGCTCAAGCTTAAGCTTAGGGTTAGGCATACCTTATGAGCCTATAAGCTGCTAGTTCTGAAAAAGAACCAAATATTTAAAAAAAACCAAAACAAAAACAAAAAAAAGACAAACAAACAAATAATTTATCAGGTCCAAGTCTTGCTAGCAATGTTCAAGCCGCTCCTTGAAGGTGGCTGTGGTGTCGGTAATCCGTTTGCAAATCCAAAGGCGATCGGCGTAAGTTTTCGCGCGACAGGCACAGACAAACAGACAGACAATCGAAAGTAGTCCAGGCGCTGAATGGGTTACGCAATTGGTTTTGGGCGCCACGCGCACATCAATTATTTCCATAGATACATACATCATTCAGATACGTGGAAAACCAACACAACGTGAAGATTTAGTGGGTTGGCAAATGCATTTTATGTTTCTTTCCCAGGGTCTCTTCCAACAATTCGCCGGTGGAAATGATGAGGGGATTCGGGCCTTGCTGGAATGGCACCGGTATGTGTTGCGACGGTTAAAACGGACGTTGTGAAAATTTCCGCTTTGGAATATATTGAGAATATTCGAAAATTTTTGTAAAATTTTCGAGATTTTCTTCTAAGCTTTGGCGCGCATCTTAGGCTTAGGCTTAGGCTTCGGCTTATGCTTGCCTAGGCATAGGGCCTATAGGGTGCCTTAAGCGAATTAGGCTAAAGCTCATGACTAGACTTATTCTTAAATTTAGCCTTAAGCTTAGGCATGGAACCCTTAGGCTTAGGTTTTTGCTTACGCTTTAGGCTTTTGCTAAGGCCTTAGCGGCATAAAAAAAGGGATGCCCAAAGTAAAAGACAACTTTTGACAAATTTGAAAGTGAAATATTATATTTTAAGCCTATTTTTTCCCTAAAAAGAAAAAATTACTTTTATAGTTTAGAAAACTATTTTTTGGCAGTGTTTTAGCCGTCAAAATTATGGCTGAAAAACAAAGTTCAAAATATTTTTCATCTAAATTCTTTTAAATTTGCTCTACCTTGAATATTGAAATAGTTTAAACAATTTAAATTATTAAATTTCAAGTAAATTCTAAAATTTTGTTCATTTATTGAAGTTTATGTTCACTCTTACAATATAAATTAGGGTATAATCCTCAAACATTCCAGAAACCAGCACCAGCCGCAGCTGGACCCCGCTCAGCTCCAGCTCCAACCAACGAGGATTACAACACCGACATCGACGTCCCAGCTCCAAAGGCAACGAAGCCCGTGCAGCTCCAACTTCCACGAAGAGCACAAGGTGCTGATGATGATAATATTGATATGACTCTTACACGTCTTGGCTAACTTGGCATGGAAAAGCCCAATTCCTTTAATACAAAAAACTTTTGTCAAAGATTCTCAAAATTTTGCACTTTAATTTTTAAGTTTAATTTTTAAAAAGTTGTGGACTCTCACGTTTGTTAACCATTTTATATGCAAATATGATCCTTATTACTAACAATTTTTAGTAATCTAAACATAAATTGGAATATTTGGTCTTTTTCCCGCCGAAAATCATCAAACATTCCTTAGCAACGGAAAATTGCAGTGAATTGTGTTGGTTTAATTTTACCGTCATTTTTTCCGCATATTTTTTGCCATAGCTCTGCTGTGTTTTGTGCCATCCTTTTCTCTGTGCTATAGAACCTGTTACGTACTTCAATAAATGATTTCTTTTAAAAGTTTTCGCACAAAAAATATAGTCGAGTAGCTGGCAAAATACACGCCATGGTGCAAGAATGTCTCATTTCAGCTTGATCTACGTTGATCTGCAAAAAATGCGGGAGAATGGAGACGCCGTGTTTTCTATTGACTTTGCCTGGTTAAGAACGTGCTGAACGTCACATTTTTTTAGACAAATTCCCGCACTTTTTGTAGAAAGCCGTGGTGGGACATCCTATCCCCACTTGCGCTGGGGGGACAAACCGACATAAGTTTTGAAGACATATTACACATATACATTTAATAACATCTATGTTTTCTGCGGAGGGAAATTAGATTAGAGAATTTCAGCAAAAAAATTCTGATAGCTTTTTGATTTATATTATAAAATTGTTCTTTTTTTTTAGCGAATTCTGATTTTTACAAAAAAGAAATTTTGCGTGAAAACGCTGCCAATATGTGCCTGTCTTACCCTAAAATAAACATTAAAATGGTTCAAAAATTATCTTTTGGAACAATTTTACGGGTCACGCGAAATACTGTCTTAGTTAGTTTTTTTTCTTTGAAATTTATTATTCCCAATATACGTAAATGTCACTGCAAGTTAGAAAATTATACTTGTTCTTTTTCCAGAAATTGAAATGTACATGATACAAGGCTGATTCCATGCAAAATCTAATAAAATTTTTAGAAACAATTTTTTGTCAGAGTCTTGAATATTGCCTTGAGCTATAAGTTACCGTTTTTTTTTTAAAAAAATCAGTTTGGCCTAAAATCTTAAGACTAAGATTAAGCCTAAGCCTACGCCTAAGCCTAAGCCGATCAAGCTTAAGCCTAAGCCTAAAAGGGCCTCAGCCTAAGCCTAAGCCTAAGCCTATGCCTAAACTTAAGACTAAACCTAAGTCTATTCACTAAAATTTTGACGTAAAACTTGTGACTAAAAATTTTGGAAAATTTTTTATAAGTCCTAATGTTTGTTTTTCTAAGCCTAAGTCTTAGTCTAAGTCTAAGTTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCCAACTCTAAGTCTAGTCTAAGTCAAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTACTGAGGTCTACGTATTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTATCGGAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAATCTAAGTCTAAGTATAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTGAGCCTAGTTCAGCCTAAAAAGAGGTCTAACGCTTGCCACTGACGCACGCTCTCTAACGCTCACCACTGAAGCCACGCCTAAGCCTTTATAAGCATAAATCAATTTGAAACTTCAGACTTAAATTTTTGGTGGCCTATACTCTGTTAAATTTCGCTTGTGATCAGAAAACGGGACCCCTTTGTTACAAAAAAAACTAACGCTCGCCACTGACGCCAAGTCTAAACCGTAATACTAAGCCTAAGCCTAAGCCTAAGCCTAAGCGTAATAAGGCGTAAGCGTAAGCGTAAGCCTAATAAGGTGTAGTGTAGCGTAAGCGTAAGCCTAAACTTAAGCCTAAATCTTTGGACAAAAATTTTAAAACTTTGACCTAAACTGCGATACTAAATATTTTGGACGCAAATCTCGGCCTGAATTTTTGGAATAATTCTGGGAACTATTCCAGAGTAATTATAATTAACAAAAAAATTTTTATAGTATTCGGCGTAAAACAAAAAATAGATGCAATGTTTTCAGTAATAAGTTTGAAATTTTCGAAAAATTAAATATTTCTTCGAAACTTCGAAACTTACTTTTCTCTGGAATAACCCCAAATTCTAGCCGCCGAGATGCCCCGCCAGTATACCGCCAAACAGCCTCGCACAAAAGCCAAAAATCGAAAGATTCCGGAATATCGGACATTCGCCGTTCGTGTACGTGGTGAACACCACACCAGCTCCTCACTTTGATAACTTCATCTGGCCACAAAATGCAGCTGTCCCAGGAGCCATTCACATTTGCTCCATGCTCCTTCCAAACTCTTGCCACCACCACCAGCTCCAGGACCCGGCGGCTCGGACTCTTGAGCTATTTTTACCGACGACAGCTAGTCCGAAGCTGTTCTCATAACACTGCTAATCAAAAAATTTGAATACTCAATACCTCCTTATAACTTTTTCAAATTCCAGATGATCCGAGAAATCGCTTCATTTTCCGACAGAGGACGCTCCAGGGATCAGGATTTTGGCGCAGTCGTCTTCAAACGCTCATGCAAGCCCTTCGAAGCAGTCTCCAGTCGGAAATAATGGTGGAGCAGGAGCTGCCGCCGGAGCCGGAACAGCTCTAGGAGTAGGTTAAGCTCACTAAAGACGTCGTGAAGTTTTACTATTTTTTAGATGCTCCAATGCTTCAAGCCCATCGAGATGGTAGTTGGGGGCAATCCAATCGCGCGCTAACCAACAAAAGCTTTTCGAGTCGGACATGGTGTTGACGGTCAAGCAGAGGCGTGAGTGTGGGGTACGGCGCAATAAGATTATTGTAGGGGTACTGTAAGATCTCTGTAGGGATACTGTAACCCTACCGTGATATTATAAAGGGGTGCTGTCAGATTACTGTAGGGAGTACTGTAGGATTCCTGTAGGGGTACTGTAAGATAAAATATCTGTTTAAGAGGTTACTGTAGGGGATGCTGTAAAATTTCTCTAGGGATATTGTAGAATTATTCCGACGTAGGGATACTGTAGAATTACTGGAGGGAACTGTAAGTGTACTGTAGGATTACTAAAGAAGTACTGAAGTATTACTGTAGGGGTACTGTAAAATTACTATAGAGTACTGTAAGATGTAGGGGTACTGTAGGATTACTGTAGTATTACTAAACAAGTACTTAAAGATTATTGTAGGGGTACTGTAAAACTAGAGTACTTTTAAGAGTACTGTAGGATTACTAAAGAAGTACTGAAAGATTACTGTAGGGGTCCTGTAGGATTACTGTAGTATTACTAAATAAGTACCGAAAGATTACTGTAGGGGTACTGTAAAATTACTATTCCGAGAGTAATGTAAGATTACTGTAGGGATACAGGAGATTAACGTAGAGACACTGATCGTAAGATTATTGTAGGGGTTCTTTAAGATTTTCATCTGTAGGGTTACTGTAGAATTACTGTAGGGTACTGTAAAATTACTGTAGGGGCACTTTAAGTTTACTGTAGGGATACTGTAGAACTACTGTAGGGTAACTATAAGTTTACTATATTAGTTCTGGGTACTGTAAGTCCCCGTAGAGACTTAATAAGATTCCTGTGGGGGCACTGTTACACTACTGATAACTAAAACGGTACTGCACGGTACTATAAAGCGACCACCCTAGATTCATGGTTATTTCAAAATTGTGCTGCCGCCCAAGAGGCCCGTAAACGGACGTAAAAAGCGAAAGGTGATTAACCGGGATCCGTGTACCGATGGAAGAGTGTGATTCCCTTCCGATTCAAAGGTGGCGACGCGAAATTGAAGAAGCTGATCCGTGAAGGCCTAGGCCTATGGGGAACGGGTGTGCGATGGAGCGACAATGCCCCCGCCAAGGATTATGTGATCTTCTTGGATCGGGGTGAGTTGACATGCCCCACAGTGTAGTTTTTTCATCAGATAGTTGGTGGGTTTTTTTTCAGATGCTACTCATCGCTGTCGATCCGGAGGATCTCAACCTTATTTCGATTCGGTATGGCTGTGAAGATCTAAGTTTTAGTATTTTATACTATTTATAAATTCAAATTTTCTAGAAAGGAATCGTTGCTCACGAAGTCGGTCACTCCCTAGGTTGGCACGAGCAGTCCCGTCCGGATCGGGCTCATGACTACATCCATTTAAGAAAAGACTGGATTATTAAACCGATGGAAACTTCGAGAAACGAAGTTGGGAAGAAATCGAGGATATGGGCGTTCCGTAATGTCGGAAGTGTAATGCATTATGGGTCGAATGTAATTGTTAATTCTGAGTCGGTAGTTTAGATACTCAAAATGATTTTCAGGCCAAAGGACTGGGACCAAATTACTATTGAGACCAAAGATAGTAGAGGGAACGATTGGTCAACGGTGAGCCACATGAAGCTTTCGTTTATCGATGTTAAGCAGCTTAACAGGCTTTATTGCAATTGTGAGTAGTTACGCAAAAATGAAATAAATTTGACGACTGAGCGGATCGAACGCCCAATCTTTCAATCTGGAGTCGAACGCGATACCATTGCGCCAAGCAGACACAGTCGCAGGAAACGGATAGAGGAGAAAAGAAAAAAATAGACAACCCTACGTTTTATCAGTGGAGCGCGGTTGCAATTTAACATTCCAATTTTCAGCTGTTTGCCCGGTTGCCTTACCCTGCATGCAAGGACGATACCCCGACCGCCGAACAATAACTGTGCGGTTTGTAGCAATGTCCAGACGGTCTCGGAGGATTGTGTGGACGTGCCGCTAAGCGCACAGATCATGGACTCCACTGGAATTTATGGGAAAAAACCCCCCTAAAATTTTCCGACAAATGCGGCGGTGCTAACAGCGACCACCGAATGGCAGGAGATGGTCTACAAGGGGAAGCGGACGTGCAATTGGAAGGTGAAGTCACCGAGCGGTGGGCGGGTTCGGTTGGTGCTCACCGAGCTAAGCAGTGTGCACCGGCGTGTAAGGCCTACAACGAGATCAAGCATAATACCGACTCCCAGCAGACCGGATTCAGAGTTTGGTGAGAACCCTAGATTCCCAAAATTCTACACCTTTTTCAAAAAAAAATCGAAAATCGACCCATTTTGGCGGGAATTAAAATTCTTTTAAAAATGACAAAATATTTTTCTGCAGAAAATGTTTCGACTTTTTTTAGAAAGCAAGCTGCGTTTCACGCGGTTTTGGCTTCCCTCATATATTGAAGTGGAAGAGTTTTTGCCTAGGCCATTTCATGGCTCGGATATCTACTGGGCAGATTTACGGCGCGTCGGATTCGGCTCGATTAGTTGTAAAACTATTTAATTGTCCGAATGTGCAGTATATGCGACATTCCCACGCGTTGTCCGGCAGGCGCTTGTCAACGGTCCACTAAAAATTGAATCAGAATCGAGCCGCGAAGCGACACGCTACGCGCCGTAAACTACCCCAGATATCGCCAAGCCAAAATGGCCTAGTTAGCTCTTCGGACATTTCAATGTATGAGGGAAGCCAGAAATCCGTATAAATTTAATTTTTTGTTGCTTAAAAAAAAAAACTAAACATCTATTTCCCAATTCAAATTTCTAGCTGCTTCAACAAAACATATGACGTCATCTCCGACCACTCTGAAGCCCTGATCCTCTCCAACGCGAACATCTTGGACTACGCGTAGGGCTCCTACAAGCTGCAATGACCGATTCAAGCCCACCCCCCCCCCCTTTTTTATCCATAGAGCGCACTCTGATTTGTTCCAGACAACGGAGAAGCCACCACCGAAACCCACGACCCGGGTGTACAGCCCGGAGAGAACCATTCCGCGGTGTGGAGAACTGGGGCGGCACCATCAGAAAAGTTCATCCTGCAAGCGATTCCAAAGATCCGAGACTCGCATCGGCCACTCGAGAGTATTACTAGTATTGTTGCGGAATATGGTCTCGCAACGCTACTTTATATATAATGGATAGTCCGACCGATTTTTGCAATGGCGTGAGAGGATTATATATATATATTTGTAAATTTGGTACCATTCCAAAAATCCAATTTATCTTTCACAATTTTCAAAATTTGCTCATCTTTCACAATTACTCGGGGATTAACACATCTAATGGCTTTCAAATTCATAAATAACAGTTCATATTTAAAGTGATTATTATATTGCAGGAACACATATATCTATGCGTATCGGACAACATATTTTGACCAAATATCTCGTATCGAAAACTACGTTTAAAGGACTGTAGCGCTTGCCATGTCGATTTACGGGCTCCTGTTTTGAAATTTACACGGTTTTCATCGTTGGCTAGCTTCCCCTCAAAAATTGAAATGGAAGATTTTGCACTAGGCTATTTTGGCCACATCGTTCAAAAACTACAGTCGAATTATTAGCGTCAAAATGGTGACTACTGTAGCGCTTGTTTCGATTGTACGGCATTATTGAGATTAATTTTCTTTCGAGTTCCCTTCGTTTTTAATTTTTTGCTTAATTTGAATTTTTTTTTGAGATATTAAAAAAAATGATTTTACACGGTCTCCTGGAGTGTTCATGATTATTGGAGCGCAGTTCCTGATCCTTGCCGCGCTGATTTACTTTTTCACCGTTAGAAAATGAGTAAAATCAAAGATTCCATTGGTCAAGAAATCTGATTAAAATAAATAGGATTATTAATTTTCAAAACCGAGTCACAGGTGGTGCCAGACTGCCCCATCACGGTTTGATTAGATCTACAAAAAATGCGGGAATTTTTAGCCAAAAAATGTGTGACGTGAGCACGTTCTTAAGCATACGTTAAGAGTTGAGAATTCTGCGTGTATTCTCATTATTTGTAGATCTACGTAGATCAAGCCGAAATGAGACATGACACTTTGACACCACGGTCCGTAAATTGACGCCAGTGCTACTGAGTCATTTAAAAAGTTACTGCCTGTCAAAATAATTGCTGTTCCCGTAATATCGCATTCAGCAGGCCACCCTATGAAAACCCAAATTGGAAAAAAATCAATAAAAATTTGAATTTTGACGGAAAAAAAATTGAGACCACATTTTTGTATCTTGAATATAAACCCGTTGTTTATCACAAAAAATTAGTGAAAATCCTTCAAATCATATTATTAGTTCGAAACGTCGACGCGTAGGTGATCGATCGTACACTGGGAATTGCCGGTTCCGAGAGTTCACCGCCGTTTGATATCCTTCTTTGCAAACTTTTGATCTGAAAACATTGACTTTTGCTACCTGGTGGAAGAGCAAACTCGGTCACTATGTTTGTTTTAGCGACAAGGGTATATGCGCAAACCTACAAAATGATCTTCAAAAAAGAATTTTTTGCCCAACAAAATGAAGTGTCAGCACGTTCTGACTAACACCGTAAATCCCGCATTTTTGTAGATCTGCGTAGATCAAGCCGGAACACAAAAATATCAAAGTTTTGAATTTTTCAAATAAAAGCCAGCACACGAGAAGCTAGCCAGCTTGAACAGCAAGTAAATAAGCCACAAAACGCGCACAAAGCTCAAGATCAAACGAGAACTTGGTCGCCCGCATTGAAACTTCTGTCATGTGAGAGAAACGGTTGGGTGGCGTGATCGTTCAAGACAAATGAAAGCATGTAGACTAGTCCATCAATCAGATAGACTGCCGCAATGACTGGCAAACCCTTTGACATCCTGCTCATCAGAACCCTGGAGAAGCCCGCAGCAAACAGACGAAAGAGCAATGTAACTGATGAGGAATAGAATGAGCTCACGGAGAAGTTGAAGAGATCTAGTCGGTGCCCGGGCTACTGCTGCTCCTGATGCAGAATCCGGTGATGGGATTGGCGGCGGCGGCTTTTGCGAGATCGCGAGCTGGCATCGACTAGTGGAGCCGTCCCAGGATGAGCATGATCACGCGGGTGCTGGAGTCGTCCTAGAGAAGATCATTTTTTTAAATCCGTTAATGGACGGAAAATTTATCATCTGGAATACAGGCTGACTAGCCCTATTTCCCGTGGTAGTGTCTTATTTCGTCTTGGTCTACCATGATCTACAAAAAATGCGGGGAAAAGAGACGCAGACTTCAACTCTCAACGTATGGTTAAGAACCTGACGTCACATTTTTAATGTACAAAAAATTCCGTCGCATTTTTTGTAGATCAAGCTGTAACAGCACAAATTTCAGCCCTCAATATATGCGATGTCCTTGTCGCCTTATTCCACGACACACAGATCAAGAGCTAGTAGCCAGAGACGCGCCGTGTAGTAAATCAGTGAGGCCACTAAAGAACATGGAACATGGGAAAGCCCTCCGACGACCGACGAAGGTGATGTAATCGGTTCACGAAATCTGACTGTCTTTGGAACTTCCAAAATTCTTTTTGAATGGTTCGAAAATATTGAGTTTGAGCCTAGTTAAGTCCATTTGAAGTTGGTGGCCTAGGATTTTTAGGAGTATTCTAGGCCGCCAACTTTGGACAGCCATAACTTGGCTGAAAATGAAAATTTTTGAAATCTAATTTCACAGTTGAATTTAGCAGACAATGAGCTTAAATTTGAGAAATATTTTTGCGCCTTGCCACGAAAGCAGACCTACAGTAATCCCGCCATGCATAAATTAATGTTAACTGAAAGCTCAGAGTATGCTAAATTTAAATACAAAGTTCGATTTCCAAACATCTCGATTTTCAGAAAAATTATGAAGACGCTAAGTTGATTGGGCCTAGCATTTTCCTCAGAGTATTCTAGGACGCCAACTTCAAACGCTCATAACTTGGCTCAGAATTAATATTTTAGAGCAAAATAACAAGTATTTAACATAACAAAAATCTTGTGATCTACCGCATACAAGATGCGCCCAATTTTAAATATCTAGGCCACCAAATGAAAACCGTGACTCGGCTCAAAATTATTTCTGCTTCAACCAAAAACCAATTCATTTATATAAAGCCCGGTGTCGGCTCAATTCAAATACCAAGTTTATTTTCAAAATACCAATTTTCAAAAAAGCAATGAGCGTTCTAAGTTGGTGGCTAGGATTTTCATAGATATTCTAAGCCACCAACTTCAAACGCTTATAACGTGGCTTAAAATCAATATTTTCGAGCAAAATAAAAAGGATTTAATAGAAAATCTTGTGATCTATGCAGAATGCATAAATTCTGCAGAGGTCACTAAGTAAAATATTCGGTGCCACAAGCCTCGGCCGAAAGTTATTATTTATGTCTGCTGAGCCAACAACCAAATTCTCCAAAAACTGCTTACCTGATTGTCTTTAAACGAAATGCTCACAAGATAAACCCATGCAAAACGAGAGAGAAGAAAATGGACGGCCAGTTTTCGTAATTACTGTGAGTGGAGCATCTCGAGACGTCTAAAAGATCCTGTTTTTGGAAAATTAGGCCACACATCACACAATCCAACACTTACGACGAGTATGAAGAGTGATAGAAGTGTTAGTATTACAGAGCTCAGCGAGAGAATCACCAAGCGTCGGGTTGCGGATTCACGTCTGAATGTACTCATTTGTTACTGAACTAGGTCTACCTAAGCCTAAGCCTAAAGTAAGCCTACCTGCCCAACCTTCGGTTCGAGCACTAAGGCACACACTTTGAGGATCGATTCAGGAACAACCCGACCTGGGCATTTACCTTTGACGCAGGCGGTGATCGACCTCCCGTTGAATATCTACGTCGATGCATTACCGTCGTCCTTCTGGAAAGACAGAAGGACGATTGATTTGAAGCTCTGTATCTAATTACCCCTGTTTGATGATCAGAGGACGGACAGATTACAATCAGATGTTCTCTGTTTTTCTCTGTTTTTTGGTAGCTAGTATAGAAAACTATAGAGTACTGTAATTCCTATTTGGGGCTTCAGCTAGGTATTGTGCTATTATTAAAAAAATACAATTGCACAAATTTCTCCTGATTTACCTCGACATGTTGAGCTTGACTCCGCCCCCAATCTTGTTACTCTTTACATTAAGGTAGATGAAAAAGGAAGATCAAATAAATGACGAGAAAATTGTGCGATGGAATTTTTTTCTATAATATCAAACTTTTATTTATCATTTTAGGACATTCTGTGATTAACTTTTATAGTTTCACGGATTTCTGGCTTCCCTCAAGTGTAAAATTGAAATTGAACCTGGCCCTAAGTTTTCACTGGACTAGGCCATGTTGGCTCGGCCACGCGTGGCGCGTCGCATTCAGGCTCGATTTTAGTTGTAAAACTAAATATTTCCCACCCGTTGTCCGACAGGAGACTGTGAATGGAGAGCAAAAAATTCATTGAGGGAGGTTTCTATTTGGCAGCTTTTGGTTAGTGGTCTTTCAAAAAATTTTTCATAATTTTCAAATGATCATAACTCTGAAACTACAAATTTTTCGGCATAAAAAGTGCTTAATATTGTAAAATGTTGCTCTGTCTAGTCTATACGATAAATCCTTATTGTTCTCAAAATTTTACATTGATAAACAGGCCAATAGGTACAGCGCCCGACAACTCGCGGGTCCAAAATTCAAAAATGGCCAAACTTCGACTCGCGAGATCTCGAGGGCTAAATCTATTGACTTTATTTTTTTGAATTTTTCAATTGGAAAATTTGTTATCCAATAGAAAAATTTATGAGCAACATATTATTAGTTAAGCGTTTCTTGCCAAACATTTTATATTCAGGAGCTATACTCATTTAGCGAAATTTTTGAAAAAGGCAAACCAAAAAGCTGGCGCGGCAAACGATTTTTTCCCGCAAATCGGCGAATTGGTGCCGGAATTAAAAATTTCCGGTAAATCGGCAAACCGGCAAATTGTCGAATTTGCCGAAAATTTCGGCAAATTGTGGTTTTGCACTGTTTTTGGAAATTTCAGAATTCCAATTTCAAATTGCAAAATTATAGGAAACTCATCCTATGAATGTTTCTATCTATTTTGAAAAGTAAGTAAATTCTATGAAATTATATAAACGACGGAAAAAATTAAGACCTCGTTTTAAGTGTTTCCGTCTTATCAAAAAAGCCCTCTTTTATCCGGCAAATTGATATTCGGCCAACGAGGGAAATTGGCGAGTTGCCGGAATTGAACCGATACTTAAACTTTCTTTCGCTGCAAACTTTGCCCTCTCATCTTGAATTGCTCCTCGCTGTTCATTAACTTTGGCCCTTTCATGCACTTTCTCTTTGTTCTCCAACGGGATATCACAACGAATCACATCGGGCCACTTGAATCCGTTCCAGCACTGGAAGACACTTTTCCTGGACGGAAAGACACAATGGACGGCATGGACCAATTGGGTTGGCTAGCGTAGTTGAAATTTGAACGATGATAAGATAAAATTGTGCCTGATCTCTGATTGAAGTCACTTTCTCGTTGCACATCGGGAAGTGACGGAGCACATGAAGAATCTACTCGGAGCAGATAACGGAGAGCAGGAAGAAGGCTTGTAGGTGCGGATGGATTCAGGAGGCGTCTTTGCATGATTCCGCGTCGACGAGATTTGTGCAACTGGAATAAGGGCTTGTAAACAACGTTTGAGAAACTTGAGATTTACAGGGTCAAAAATTGCTCACGACCTCTCCGGGTGCCGATAAGTTCTTGTGCGGAAATTTGAGCAACCAAAAGTTCTGCCGATTGCCGTATAAATCGGGTACGGCAACTTCGGCAATCGCCGGTTACCGAAGAATGTTTTAGAGTTCTGCAACTTCGGCAATTGGCGGTTGCCATTTCTCTCCACGAAATTTCCCACTATTAGATTAAACAGCAAGTGCAAGTGGGGGTGACTCAAACAGGAAAGAAATCCGGCACTGGTGCCGACTTGCCGGAAATTTTCAATTCCGGCAAATTGTCGGTGTTCGGATTTGCCGTGTGCCGGCTCTCAGATTTGCCGGAAGTGTGTAGAGGGATTTTTATAAGACGGTAACACTGAATACTCCATTGTGCCTTTTTGAATTTTTCAGTGTCGTTTTCTTTGGCTATTCATAGAATTTGCTACTTGTATGGGCAAAAAAATGTAGGAACATTCATAGGTTTAATTTTGCTATTTGAAATTGAAACTCTGAAATTTCCTGGCCAAAAAAATGCAAATCCACAATTTGCCGGAATTGTTCAATTCCAGCAATTTGCCGATTTGTCGTTATGCTGGTTTGCCGGAAATTTTCAATTCCGGCATCTTGCCGATTTGCCGATTTGCCGGATTGCCGAAATTTTTCAATTCGTTAGCCGTCCACCCTGGATCCTGCCATCCAAAAAAAAACGGAAACCATTTTTGGCACATTGACGTTTTCCGCCGGCAAATTCGGCAAATCCATGTCAATGTGCTGCTGTGCCGTTTTGCCGGTTTGACGGAATTTTTCTATTCCGGCAATTTGCCGATCTGCCGACTTGCCGGTTTGCAGGAAATTCTCAATCCATCCGGCTCAATATGCTGACGATTTGTCGGAATAAATTTTCAATTCCGGCAATTGACGACGGTTTACGGCTGGAAATTATCAACTTCGGATTTTGCCAATTTGCCGTCTGGCCAAAAATTTAGGGTTAATTCGGTTCGCCGTTTTGCCAAAACTTTTAGGGTTCGGCAACTTCGGCAGTTGCCTGTATCCGCACATCCCTGTCCCACACCCCAGGTGGAAGAACTGGTGGGAGTTACTAGCGGGTCCATCAAGAATGGGACAATCATCAAGTCAACACAATCCTTAGCCGACCTTCCCAAATTCATAATTCCTTCCTTCCAAAGGCAACGGTTTCCGGTCCTTCCAACTGCTTAATACCAGCCACCACCACCAAACCCTCTCCTTCTAGAGAACAAAGTTGCATACCCCCTTTCATTGTTTTGGAGAAAGGGGCGTCTTGTGGTGCTAGTCCGGAGAGCCTGAGGACGTGACAAGTGATAGACGGGCTTATACTATCGGCTCGTCCATTGGATTTCATGCGCCTAGGCAGAGTGCACGGCGGGAGGTGGGGACGCAGGTTCCCGTCCAACTATTGCCGCAGAGCATCCCCTATCTGCTCCTATCAATTGTTCGGAGAGACTTTTTTGTGAATTTTGCCTTTTGCAAGAGGTCTGAGATTTGGGATTTGGGCTTTAGCCTTTAGGCTTTAGGCTCGCTTGCCTTGCGCCAGAGAATGGAAATTTGTCCGTATTTTCCCGGATATCAAAATATGATCGAGGCAACTATAAAAATATAGTAAAATTTTCCAGGTTTTTTGTCAGTTAGTATTTATTGATTAAAACAAAAGAGAGCGGAGATATAAGCTGTCAAAGTAGAAGGGTGGTTTGATCTACAAAAAATGTGGGGATTTTTTTTCATGCTGATAAATAAAAAATGACTCCCACAAATCCAATAAGCCTCAAACTTAAGTTCCTCCAATCTCATCCCCCTCATAAACCATTAACTAAATCGGAGTACTAGATCGCCGGTAGTATATATCAGAAGAACAGTTGCTCTCCCTCTCGAACCGACTTACACTTGAGAAATAGAATAAATTGTGGAAGAGAAGTGACGACATCATAACCTACCACTTCACAAGTTTAGATATATATATATATATACGTACTAGTTGGACTAGCTAGGACCTAATTTAGAACGCATAGGTATCGCCTGTAAGTGAGGACCTAATTAGAACTCACTAGGACTATAGTATATATATATATATATATATATATATGTAAACAAGAACCCGGGCGGGTAACCCCTTACGGTCAGAGGGGTGTCCTACACCAAGGGTATGTAAAACCGTGTCCTCCAGATGTCGACGTTGAAAGGGAAAAAGTGCAAAAGCGCGCGGCTTCGCGCAAACCGTAGCTGATCCAATGTAGCAACGTTTTTGATTTATTGGAGGAGATATTTTGCCAAAAGTGAAAAAAAAGTGCCCCATATGAGATGCGTAATAAAATTCCCTACAAGACCTTAAGAAAACGTGGCGTTGGCTGGCAAAAAACAGGTGGCAATGATAACGGTGTAGGTGTGCTTGTGTGTGTGTGTGTGTGCTAGAAGAGCATAGGCTCGTGAATCGTTATAATTGATGCTGGAGGAGAAGGAGACGATGGGCCTCCAAAGTGTTACACCTGGTATTGTTGGGAAAAAATTGGGAGAAATAGGCATTAAACTACCTAACCTAATTGAGTTTCAAAGCTTATCTTATTATAACTAAGAGGTGTGATAATAGATAATTAAAGAACTTTAAACTTATCAAAACAACGCTTTCAAATCTGTAAAGCTGAATTAGGATTTGCGTAGTACTAGCTAAAATCTAGTTGGGACCTAGGTCTGAGACTATCTAGAAACTTCGGACGGAACTATTTAGGAACAGTTAAGTCTTAAGGCCTGCTTGGGTACAGGTAAACATGTTTAGAATAGGAACTAAATAGGGAAGTACTAGTTAGACTAGTAAGACCTAATTAGAACCTAGGTAAGGCCTGTCAGTCAGGACCTAAATAGGGCGTACTAGGACTTAGGTCTAGTTAATGTCTTATTAGGACTAGTTAGGACTAGCCCTAATTAGAACCTTTTAGGTACGGCCTGTTAGGGAAGATCTGATTAGGCTTTAGGTAGGACTAGTTAAGATAGAGTTAGGCGACTCGAAGTTAGGACTAGTTAAAATTTAATTAGAATCTAGGGACCGTCAGGACCTAATTAAGACATACTAGGGCTTAAGTAGGACTAGTTAATACTAGTTAAGAACTGAACATAGGCACTGTCTCTTAGGCCTAATTAGGACTCACTAGGACTTAAGCAGGGCTAGTTTAGTTATTGTTTGCACTATTTGACTAGTTATGTACCTAATTTAGTACTCACTAGGACTTAGGAGGACTACGTTATAATGCCTTGTTAGTAATATTTAGGACTAGTTAAAATCTAATTAGAACCTAGATATATCCTGTAAGTTAGGACCTCATTAAGACTTGATTTCCGCTAGGATTTAGACAGGACTAGTTAAGATATTGTTTCGACTAGATTTTTGACTAGTTAAGAGCTAATTAGATCTTAGGTACGGCCTGTAAGTTAGGGCCTATTAGGACTGAATAAAAACTAGTTTGTTACGAATGTAGTTAGGACTAGTTAGGACTAGTTAAAACTTAATTAGCACCTAGGTACGGTCTGTTAGGGAATACCTACTTACCAGGCCTTAGGTAGGACTAGTCATGACCTAATTAGAACCTAATTATAACCATTTCTGGGCACGGCCTGTTAGGGAAGACCTAATAAGGACTTACAAGGACTTTTGTAGGACTAGTTAGGACAAGTTAAGACCTATAGTGGTTGTCCTGTAACTTCGGACTAGGACTTACTAGGAAGGTAGGAAGCTCGTTAAAAGGAATAGTTGAAAATTGGGACCTCATAGTTAGACCCTTAATTTTGTACACATCCTTATTAATATCAAGACACATTTTAAAAAAAAACGACTTTTTTAAGTTTAGCTATATAAAACTATAATTATGGAAAATTTGCTGCTTTCCTTGAAATTCGAAAAACCTAGCGTTTCTATAAAAAACCATCTGGAAGTAAATTTTGAAAAAACCCCGTCATCCAACAAAAAGAAATCTCACTCACTCACCTCGTTAAGTTATCGGCAAATCTTTGCACATCTCATGCACCTTTTGACACCTCTGCCCGTCCACACCAATGTCACAAAGAGCAACAGGAGCCTTCCTAGGTTACCCCGAACCACGACAGATGGCATTAATGCTAAGGAATTGGGCTCACAGCCTAGAGAGGGTGGGGGAAAATATTGAGAGTAAAAGAAACAATGAGAAGAGGGAAAGACGGAGGATAGGCGGGGGGGGGGGGGGGGGGCCACAACAGTGGCAGCACCACCAGGGCCTGTCCGTTGACAAATGACCCAAACGGACGGGTGGGGCAGACCTGTTGTGTTTGTTGGGAGATGGCTGGCGGTTATCAGATACTTGTATTAATGGTATAGAGAAACACCAAGAGAGCTGAAAGATGGAGAGGCGAAAGAGGAAGAGAGGGGGGGGGGTGGAAGTTTTTACGAGCCCTTAATAAATATATCGAATCAGGAAATCATTTGATGATAACGGAGGAGCGCGGGGACGGAGACGGATCATCATTATGAGGACCGAGGGGTGTGCGGCGAATTTTTGCCGAATTTGCTGTTTGCCGAGCTCCGCAATTTACCGAATTTGCCAAGCTCGGCATATTTCAAAAAAGTAGATTTGCCAAGTTTGCCGAACTTGGCATATTTCAAAAAAGTAGATTTGCCGAATTTGCCGAGCTCGGCATATTTCAAAAAAGTAGATTTGCTGAATTTGCCGGCCGAGTTTGCCGAGTTCGGCAAATCTGCCTTAGCCGAGCACGGCATATTTCAAAACATTTGCCCGAATTAGCCGACCCGAGCTTGGCATATTTCAAAAAAGTAGATTTGCTGAACTCGCCGATCTCGGGAAATGCCTATTTAGCAGCACGGCCTAGTTCACAAAAGTAGATTTGCCGAATTTCCCGAGCTTGGCATATTTCAAAAAGTAGATTTGCTGAACTTGCCGGGATCGGCATTTTTCAAAAAAGTAGATTTGCTCAATTTGCCGAGTTCGGAATATTTCAGTAGATGAACTGTGCCGAGCTCGGCATTTCTCAAAAAAGTAGATTTGCTGAATTTGCCGAGCTCGGAATATTGCAAAAAAAGTAGATTTGCCGAATTTGACAATCTTGCCGTGCATGTTCCCCAATTGAGTTTGCCGAACCATACTTGGTCCAAAAAAGGAGATTTGCCGAAATTGCCGAATTTGCCGAAACAATGTGCCCATGGCGAGCTCCTGTTGATTTTTTTCCAAAAATTCAGTAAAACGACACAAATTTGTTTTAAGAATTCATTAGTTTCGGTGCTCCGAACAACATCACAAAAGATCAAGGGATTTTTCCGAAGTTGTTAAGCACAATTTGCCAAATTTGCCGAATCCGCTAATTTTGAGATTTGTCGCACACCCCTGATTAGGACCGAGCAAAGGGCCTAACATGATCTCACAATTTGAAAAATGAAATTCAGGGATTATTCTTGGGAAAAAAGTATGAAACTCTTCCTCCGCCCGTTTCCGGCAGAAACAATTGAACCAAACGAGCCAAAAGTGCAGTGTACAGACACTTTGTTGGGAGTGGAGAGAACCAGAAGAAAGATGGAACTTTCTTGCGATGAACAAATTTTGGATCACTGGAGGGAAAGATTGGTGTTTATTAAGCTTTTTAAGTCAATATTTAGAACTCAATAGGCCCAAACAGGCCTAATAGGCAAATAGGCGAAGTAGATTAAATATGCCAAATAGGTATAGGTTGAATAGGTAAACAGGCCCAATAGGTCAAATAAGCTATAGGCGAGACTGTTGCTCAGATACTTTTTGACCTGGTAATGTTTTTCTACACGAAAAACAAAAAAGTCCCTGCTCTATTAGTTTCGGCAGCAAAATTGTGATTTTTTTCAAAAGTTTCCCATTTGTGCCACTTTTCAATAGTTTTTGATGGGTTAAATCTATATTTTCTGAATTCAGCTTATATGAATTACCCGTTTTCAACAAATTTAGGCAAATTTTTATTTTTGCCCAATCTTTTTAACCATCTAATGACTGATTTTGGGTAAATTTTCCTGAAATTGTACAAAAGCATTAGAAATTGATAGGCCAGTTTATAGGCACATGAGGTTTTTCGGAGTGGGTAATCGTCGTTAGGCGAATTATTTGGTTGACAAATTCGACAAATGCTGGTTTGCCGATTTGCCGGCAAGTATTTCATTTCAAAATATATGTAGGAACATTCAAAGGACGGTTGCTTACAATTTTGCCGGATAAAATTTAAATCTTCTGAACTGAAATTCCTTTAAAAAAAATGTGCAAACCCATAAGTTGCCAGATTTCTAATTCCGGCAATTTGCCGATTTGCCGATTTGCCGTAAATATCAATTCTGGCCAATTGAAGATTTGTCTTATTTTCCGACTTGCCGCATCCCCTGATGTAGGCATCAAAACGAATGTACACCAAGTTTTTTTCAGAGTTTTTAAGTTTACCTTCTAATTATAATTTTTAGTGAGGCTCAAAAAGTTCCAAAATTAATTCTGAAATTTGCTCGGCAAACGGCAAATTTTCCGCACACTCCTGTTTTAAATGTTCACCGCATATTTAATTATTCCGGAAATCTGATTCCCTCAAACAAGTTTCCATCAAAAGTGTTTTCCCTGATTTGTTGACTCTGACACCGACGGTGGTCGTTCCCCCCCCCCCCCACTCTCTCAATTGGCATGTAAATGACCCCGTATGAATGAAATGCCTTTTGGCGGCATAATGCATATCGCCTAGTACCATTATTAATCTTCCATCCCCCATTGTCTCCATCTATATAGGGGGGAGGATGCGTGATGCGTGAAATATGCAAGTGAGACTTCAAATTGAGCGTGTGAGATGTAGTGGCAGATGGCTGGCTGACAACGGATGAGCTCAGTTCCATCGACTGTATCACACGGAGGACTTGGAAGAGAGCAGGGAGATGGATGGGGGCAGATGGCGTCATCTATGGACCATTTTTTTTGGAGCTGTTCACTCAGATATTAGGGTATTCTAATCCCCTTTTTAGGTCTATTTCTGATCGTAAAACTTGTTCTTTTCAACTCATTTTTAATTCAAAAATTTCAAAAGTTTGTCGTAAAAATTACACAAAAACCTAAATTTTGATCTGATTTGAGGCATTTTAGTCCCTTGTTAAGCGTCTTCGATGCACCATTGTTCAACTTGTTTAAACTTTTTAGTTCCGCATTCGAGGAAAATGGAAAATAAAAAATTTGTAAAAACCAGACTTAGATTCTCCGTAACAACGCTTTCATGGGAGGTCACACGCCCGGTTTCACGGCCTGATGCCTACGTCAAACCTGCCTCACGCTGAGTCGGCCTCACGCTCCATTTCTGAATTTTGGCGAAAAATCAAATACTTGGTCATAGTGAAAAGGTAATTTTTTCAACCCGACACTTTTCGGGTTCCGCGCCGCACTATACATGAGGCGAGGCCCGCGGCGCGAGGCAGGAGCGGAGGTCGCAGCAAGGCAGGCGCGGCAAGCGTTTTTGCTTGCATGGATACCCTAGTCTAGACAAAGCACGAAGTTCTGGCTTCCCGCATAAATCGGGAAGAGTTTTTGCCGAACTTGGCCATTTTGGCTCGGCCATATCTGGGGTAGATTTGGCCGTCGTGTTGCGTGTCGTCGCGATTTTAGTTGTAAAACTAATTATATTTGTCCGTGTGGAGTACACGACTTTCCCATGCGTTGTCCGGCGGGCGCTTGTCGATGCAGCGCAAAAAATTCAATAAAGGCCAGAACCCAGTGAAAAAGATAATTTGCGACACTTATAAATAATGTTTACCATAAAATTTTTTTTTGTAGTTTTGATTTGTGGCTCTCCTTGTTTTAAGATGTGAACAAGTTTCATCACCGCTGTAAATTGGTGGATTTGTAAAAAATTATGTATTTAAAAATCAAATCTTGATTCTCCGGGATAGAAGCATAAATCAAATTTATTACTGTAACATGTTCACTTTCAGTACGTTTCATTGAAATTTTTAGGCTTTGAATTTTAGGGCATCATAGTTTTGCCTTCAAAATCCACTTGCCCAAAAAACAAGCCAATTCCTACTCGGCGGGGGACGATGGTTCGATAGCATCAATCATATCGGTGTGTGTGTGTGTGTGTGCAAGGCGGGGGATGTAGCTGGCGCGCGAAACGAATAAATCAAGAAACGTCTCTATTTCTGCGAGCACGGATTTCGTTGAGAGCCCGGGCGCTCACGCGGTCTAAAGGAGGAGAGGGTAGTACCACTTCTAATGCAATACAGGGCATACTTCTTCCATTTCCATGTTTTTGTACTGTGATAAACCAATTGTTAACTAGCCAGAAGTGGTTCACATGTTCCGTAAAGGTTTGCAGGGTGTACTGATAATGAATGTCTATTGCTCTGTGAGGAGACAAAGAGGCAACCGAGAGCAAGTCAGTTAGGTTAGGCAGGTGACTTTTCAATTGTGACCAGGAAAAAGTACTTTGGGAATTTTTTTTTATTTTTTGGCTACTGGCCAGATTTTCAGGATTTTTCAAATATTTACAGAAATTGATTCTACATTATAATATTTCTGTAATTTTCTCAATTTTCAAAAAATAGCCAATTAATTTTGAAGTTTCGAATGATTGCCGATCACAAGTTGCCGACTCCCAAGAACACCGGCAATTGATGGCCCTTTGCCGGAAATTTCGAAAACCGGCAATTGCCGAAATTGCCCATTGCCTTGGAAATTTCGAAAACCGGCAATTGCCGAAGTGGCCGACTCCCGGAAATTTTCAAAACCGGCAATTGCCGACATTGCCGACTCCCGGAAATTTTGAAAACCGGGAATTGCCGAAGTTGCCGACTCCCAGAAATTTTGAAAACCGGCAATTGCCGAAAGCGCATTGCCGATTGCCGGAAATTTCGAAAACCGGCAATTGCCGAAATTGCCGCTTGCCGGAAATTTCGAAAACCGGCAAGTGCCAAACTTGCCGAATGCTCCGGAAATTTTGAAGACCGGCAATTGCCGAAATTGCCCATTGCCGGAAGCCATTTCGAAAACCGGCTGCCGACCAAATTGCTAGCCGGAAATTTTGAAAACCGGCAATAGCCGAAACTGCCCTTTGCCGGAAATTTCGGTGCGAATACCGGCAACGACCAGTTTCCGACGAAATTCGAAAACCTGCAATTGCCAAAATTGCCGCTTGCCGGAAATTTTGAAAACAGGACACTGCCGAAACTGCCGAAACTCCCGGAAATTTCGAAAACCGGGAGACCGAAATTGCCGACACCCTTTGGGTAATTTCGAAAACCGGCAATTTCCGAAATTGTCGATTGCCGGAAATTTCCGATCCCTGAGTTTAGCCTTTTTCAGCAAATCAAACAGTTTATGATTCTTTTAATTCAAAAATTGTTCTGCAGTGATCTTGCATCACTATTGCTGTGGCCCTCCTTTCAATACAGTACTTTCTACAGTACCACTACATTATTGATGCGTAATTTCCAGTAATGCCATTCGTACACATTGTACCACTACAGTTCCTACAGTACCCTATACAGTACCGTCGCAAAACAATTACCGTAACAATGGAAATCTTATAATAGACTACAGTGTTATACAAAAACTACAGTAACCCCCTTGAAGTTAGTGTACAACTTGTAAATGACGCTTTTTTCTTTGTTTTTTGCTAAGTTCAGAAATTGTAGAGTGTTTTTGGCATCTGCTCAGATTTTCAGAAATTTTCGTGATTCTATAGTAGTCTTTTTAATTTTCTCAATTTTCAGAAGTCTGCAAATTTAAATTGAAATTTCGTGAATAGCTTAAAAAAACTCAAACAGTTGGCACAAATTTTCGTAGATTCATGTACGAGTTTCAGCCTTGTTCAGCAAATCAAACAGTTTTTTATTTTTTTTTGATTAACGTTTTAATTGTTCTCACCCCCTGCAAAGTACTATCAGGTCCTAACGGTAATATTAGCCTACCGTATCACTACATAGTAATCTCCAGTACTTCTGTGCATGCTGTACCCTTGCATCATCATAGTGGTCTTTAAACCTACAGTACTTCTGCAGTAGCACTACAGTACCACTCAGAATCTCTCCATTAGATAGACGGCGTCTCGTATCGTACCACTACCGTAATCCTACAGTACCGCCACAATACCATTACGGTAACACTATGAAAATCTTACAATAACAGTATACAGGCCGGAAACTAAGCCCCCTTGAATGTAAAACTTGCAAATCTCTACCGTTCCTACAGTACCCCAATGCAGTACCACCGCAATACAGTTGGCATAACACTATGAAATCTTACAGTACACTACAGTAGGCAAAAACTACAGTAACCCCCTTGAAGTTGGTGTAAAACTTACAAATGTTCAGCTTTCTTCTACAAATTTGCCAATAACTTGTAAGTTGGGGGAGCGCATCGAACTGTATACATATATGTACATGCCAACCAATTATTTTATCAAACAATTTATTAATAGTCGAAGACACCTGAAGCAACGATTAGGAGGAAGAACACGGGCAGGGAGATAGGCAGAAGAAGAAGAAGAAGACGAATTAGTTGAAGAATCTGTTGAAACGGACGACGTTTGTTTGTGATGTCGCTGTGCGACAGCTTCTCGTTGCGGACGGAACGATGTTCGCACGGCGAATTCGGTGGCGAGATGTCGGACACGTCGATTGTCGACGAGAAGGGATCAGTCGAGACGGTTGAAGAATGCTGAGGAGGAGGATTATGTCGACGTTCCCGTCCACGACACGGGCCTGGGTACAAGTGATACAGACGTGAAGGTTACAGAAGATGTTCACCCCGTTGCGGAGGTATAATAGTCGTTGAGAGGTGGGTGGTGAACATGAACAAAGAACTTAAGAGGCTTCGTTGGGAATGCGCAGGCCTTACTGCTATGTGGTTGTAGAAGATGGTCTTACCATTGCGTCGAGGCACTTCAAAGTCCCCCCACACCTGGAACACAAAATTTTCAATGGTAGTCTCAAATAATATGCAGTGGCCGATGCACTAGGATAAATTGCCAAACAAGGTGCATCGACGCTAAATAATTTTCTTTTGAAATTTCATTTAGAGATGTTTTGCTGCGCAGACTTTCAATCATCTTTTTAGTTTTCCTCTCTAATATCATCAGTGCATCGAGAAAAAATGTTATAGCAGGAGTAAAGAAATTTGAGACTTTACTTATTTAGACCAAAAATGACCCAAAATTAACGAATTGTTTAGTAAGACGTTTTGAACATTTTTCAAAACAAAGTTCTGGCGGTTCAAAGTTCTGGAAAATAGCACATTTTCAGCTAAAATCTAACCAATGTTTTGGGGGTGTGGCTGGGGGAGCTAGGAATCAAAATGTAATGTCATTTTTTTGTGCCCCACTGCCCGTAAATGGACTTTAAGCGACGAATAATAACTGTAAGGGCCACAATATTTATAAAAGAGTTATAGTTATAAATAGAAATTGAGTTCCGCCCGACCGAGAAAAAACTTGACGAAAATTTAGCCTTAATTTTAAAATGGGACTTTTTTTCCAAAACATTGAGCGATAACTCTTTTTTGAGAATTTTACGTGTCATTTAGAGTAAATTCGGTAGATTTAGGTCATTTTTGATTACTAAAAAAGTAAAGTCTCAGATTTTGATACTTTCTCGATGCACCATGATGAAAAGAAAAAAAGAGAAAGTTTAGGGTTAAAAAAAAGAAATCCGTAGAACCCTTCCGACGTTTTGGGAAAGTATAGCAAAACAAAAGATTTGTAAAAAATTCAATTTCAGTAGGTTCCCCCTATTAAATTCTCAATTTGTATCAATGCACCATACATTTTCAGCGTGAGATTTTGTAAAATGGACAGGAATGAAAATTGATCAGGTGTGTATAAAAAAGAAATTGACATTTTGTTTTTTTTTTTGTCAATACACCATGATGAACTTCACGTCAAACATGGTACATCCTGGAAAGGAGAGAGTTTGAAAAATGTATCATTTTATTCTCGATGCCATGAAGATTTATATTAGTAGAAAAACCTTAGCATAAGTGGCATAAAAATAAAGGTGGAGTAGCGTGGGGATTTTGTCTACACTTATTATGATCCAAAACGATAGAATATCTTAATTAAACACTCCAAAATATTTAAGATTTTTCAAAATTTCCGGTAAAAGTTTTGGCAACTAAATATGCTTGAAAAAAATATGAGCTTTTGAGGAAATCTCATCCAAAGCAATGTCGCGTGTTTCGACCCACTGTTTTTATGGTCGACAATGTAGAAAAAAATTTTTTTTTGGTCGACTTTTAAAATTAAGATGGCAAAAACTTAGTAATTGCCTATTTGACAATAAAAAATTTTCAAAATTGAAAAGTTTTATTATGATATTCGATTATTCTGGCACCATGTGAGTATGGTTTGTAGTAATTTCCCCACTGGGCTACTCCACCTTTGCTTAAAATTAAAAAAAAAATCATAATCACAGGGGGATTATTTAATATCAATGAAAGTTTCGATTTTTCCAAATGTATCAAATGCAGTTTTCAGCGCGAAATTTATGTGCAGTACTTTTTCTTCCAATAATATATCCCGAATGATGCATTAGTTATGGGCTACACGATTTGTTAGAAAAACTGGCCATGCTTAAAGGTGGTGAACCGAAACTTGATACTCTGTCTTTTTAGATCCAAAACGGTCCAAGACTACCTATCGAATATTCGTATTAACCTGTTCTGAAAACTTTTCAAAAAAAAAAGTTATGGCCGTTCAAAGTTTTGGAAAATGGTCGATGTTTAGCTAAACTCTCAAATTTTGGCAATCAACCGTCTGTCACAGTTGGAGCTTAATGTTAGAAACAACACGTGATAAATTGCAAAAACATGCCTAAAGGTTCCAACCGCTCCGACACAACCAAAATTTGAATTTTCGCTAAACGACCATTTCCTCTTCCAAAACTTTGGGAGGTCATAATAACTTTTTTTTTTGAATAAAATTTTCAAAACGTCTTAATACGAAATTTGGTAGTTTTTGGACCATTTTGGGTAAAGGCAAAGTATCGGCCAAATTTTGGTACTTTCCACTCAGCCTTTCAAGCAGAGCCCCTTTAAAAGTTTGACCGAGGTCCCAAAATTTTGTAAGTTTCTTCCATGAACCATGATGATTTTGAGCAAAATGTTAGTTTTTTTTTTGTGCTTGAAAAACTGGTGGCAGGACAGTTTTCGGGTGTTAATAAATATTTCGATTCACTATGTTTTTTTTAATGAAACCGTACCTCCCTTCAACACAAGTCTGCACATCCGTTCCGTCTGTGGTAGCTCGGAGATCCCGCCATTCGCCCAACACCTTCCGATTCGTCCATTCTGATCATCGCTCATTTCAACTGTGTACGTCTACTATTTACAAATGCTAGTTTCTTATGATTTATGGAGTCATCCTGACTTACTATCACCAACTGCTAACACGTTGTAGCTGAATCCAAACTGTCCCCGTTTAGACGCTCACCGAACTCGGTAGTCGACTGTCTGAAACATTATATGGGTATCGCAGCGATAATTTTGAAGCCTTACCTTATTATCCGATAGGCAGCTTGCGTGGCATCCGAGCACTTGATAGTGATTCCACCAAATGATACGGTCACCTGAGATTCTTTAGGAACAGGGGCAGAAGGTATACATGCAGGTCAGAAGGTCGTTTGTCGGTTTTTGCACCTTGAATCTTAAAAAAAAACGATGAGCAAGTTATTTTTTATTTTTGTCTATTTTTGTTCGTATATGGTTTTTTAGGTACCATGGAATAAAAAAAATGCTCCAAAAAAAATTAGTTTACAAATATTACTGGTACAGAGAGTGTAGATAGTTAGAGAGTGACTGACCGCATCCGGTGTGGACCCAATGGGGCGGGGCGCGCGGAAGGAGACGATTGGTGTCGATTTACGAAATGATGACAAAGAGGAACGTAAATCGACACAAATCGCCTCTTCCGCGCGCCCCGCCCCATTGGGTCCCGGATGTATGTCACTCTCTAACTATCTACACTCTGTAGGTCCGGTAATACCATAATATGATCATTATGGGCGTCTACATTAGAAAAAAATCGATCTGAAATCACAGATTTTTGGCCTCCCTCATAAATTGAAAAGGAATAAGAGGTTGCGAAATTAGGCCATTTTGGCTCGGCCATATCTGGGGTAGATTTGCGGCGCGTTGCGTGTAGCGTCGCGGCTCCATTTTAGTGTAAAACTAAATGGAGTTGGCCGTGTGGAGTACACGACTTTCGCGTTGCCCGACCAGCGCGCTTGCCAATGGAGCGCAAGAATCAATGAGGAAGGGCCATGGCGCGCCAGAACCCCATGATTTTTAGGGTATTTCGAGGTTGGCAGACGCAATATGCTGGAATCTTTTTGAAAAATTTTTTTTTTTTTGAAAAACAAATTCCAAAAAATCTCCTCATCGATCGAAACATTCTTGGGTGAAAAAAGTTGCACGATTAGGAATTTCAGAAATTAGAAAAATTCGAAATTAGGAGAAAACAGAAAATTTCCAAACTGCTTTCAGAATACTTGTATACATGAAATAGCCTAAAAATCATGAAATTTTTCAATAATTACTCTAAACTAGCCCAAATTTGGTAGTAAATATTCACTGGCAGCAACTTCAGTGCGAGATTTTTCTACTCAGTTTTAAGTGCTCGTATGTCGCTGAATTGTTTGTAGGTACTTATTTGAAACTCTTTTGTCAAAATTCAAAAATTTAATTTTCACGTTTAAATTTTGAGTAGCGCCAGTGGGGGATTTTGTCTAAATACACTCATTATGATCCAAAACTACCTGAGTAATTGCCACTATTTGACAGTAAATAAAACCACGATTTACAGAAAAAAAAAGTTGTATTATGATATTCGGTCACTTTGGGACCAAATGAATGGTTTTTCAAAATTTCCCCACTGGCGCTACTCCACCTTGAAGAAACTGAGCGGAAATACTTTTTACTCCTTGTGAGTATGGCAAAAAACCTTGTACCACATGGCAAAAGAAAACCCACGCATTGTTAGTCATGACAACTTCGGTCTCATTCTCCAAATTGCCGCCTTCTCCGTTCTCCTTGGTCGATCAGCCAGTCAGGCATCTAAGCAAATAATGCCCAAAATTCAATACATCCAGCAAACGTTCAACTGATATTTCGTGTCCCATTGAAGCGTGCCATTTGAATAGATACACTTTGGATGGCCCGCGTTTGTATCGCACGGAAGTTTTCGTCAAACCTGATCTTCAATAGGAATCTGCAATATTGAATTTTTTTCCTTTTGGTGGTGACCTTCAAGGTTTTGGCCTGGGTTTTTAATCTTCCATTAAATCCCTTCAAGTTCGCTTTTTCGAGAGTTTAGTTTCTAGGCCGAGGAACTTCTTGCAGCCAAATTTCTAAACTATTGTGTTTTTGCCAAATTCTAACAAAGAAACATTAGGTCAATTACGTCATATTCTTGCCACATGCAACTTTGTCGTCATAGGCCCACATCATCCGAAAAGCCTAAGCCTGAGCCCAATCGAAGGTCGCTTGAGCCTAATGTTCAGCCTAAGCGTACGCCTAAGCCCAAACTAAAAGCCTAAGCCTGAGCTCAAGACTAAGCCTAAGCCTTAAGAAAAACCGGAAAATCCTAAGCCTAAATAGCGTAGCAAGCTAACGCTCGCCACTGACGCCAAACCTAAGTCTCGGCTTAAGCCAAGGCCTAAGCCTAAGCCTAAACCCATGATTAAGCCCAATCCTAGCGAGCCTACGCCTAAGCTTGAACCTAAGCCTAAGCCTAAGCAAGCCTCAACCCAAGCCTATAATTTAGGCCACCACTAATGTTTTCAAAACTCGATTCTCAAATACTTTTTTCAGGATATGAAAGTAGGACAGAAATGGGCAGGGTATATGGTATGGAGCAAATATCACAAGATGGATCAGAAACATAGATACGGGGTGGGAGTGTTGGACTAGGTGACTTTTCTAAGCCATCCCTACCTTATGTGAACACACGCATTCGAAGTGTCCACAATGGCCACTGATCGAATCAGCGGTGGCAGCACCACAACCACCGACCAAATGATCCAGTGCAGAATGATAAATTTGTGGAGGGAAAAATCGATAACAGTAGGCTCCTGAGGGTAATAGTAGTAATCATACATATATGGAAAAATGAAGGCAATCCAAAAAGATGTGTGCGCTGGTTGGGGTAGTGGCATCAGAATAAAGGTGGGATTGGGCGGTATAATTGGAGCGCGGCCGAGGAGGAGAATCCCAAAAAAGAAGGAAAGTGCAAAGAGGAGAGTAATGACATGTTACGGTAGACAGGACAATGCAACTACCTAATTATATGAAAGAGGGGGGGGGGGCGACGAGAAGAGAAAAGTCTTACGCAATTTGCAATCTACTTGCCGACTTTCAATTTCTGCTAGAAATCGAAAAAAGGAAACAAATTCCAACTCAACTTTTTCGATATCATCACTTCCGTGGCACGGCACACGTCGGAGCAGATTCAACGACGTCTCGCGATCCCGACTCGCTTTACCCATCCCATTGTTCCCCTGATAGTCGATGAGCTCGGAGATGTTGACCCTGAACGTGCGATCGCGGGTAATCGCACTCTCTGGAATTTTGAGAGCTTGGAAGATTTGCCGGGGGGGGGGGGGGAGGGTCTTACGGTGTGATTGAGTAGGATGATTTGTGCCGTTCAGGCGGGTCGGCCAACTCAGCACGTACTTGCCGGGCGTGTGGTCGCTTAGTCTGCAAGGAACTGGCCAAGTTTGAGCGGCCGACAGCATGCGGGTCTTTTTTTAGAGAAGGGGGACTGTGAGGTGTCCGCTGCTTCAGACAATCTTAGCATCATGCAAACCTTGCATCTTTTGTATTTCAGGAAAAAAAACAGAATTTTTTTTGAGCAAATTTCAGCCTAAAACAAAAATCTAACAAAATTTTGGGAGGATGAACTTATTATACCAAATTTTTCCCTGGTCTTTGAAGAAATTTAAAGCCCCGTGGCTTCTGATATTATCAAACAAATTACAGATATGAAATGTGACTGAAGCTTTAGGTCAGAAATACATAAAAAAAGGATTTTTCATACTATTTTTCCAGTCAAATTTGATTTTAGGCTTTCAGATTTATCTACGAAGTCTGTTAAAATAGGCTTATATTAAAAAGCTATCCGATTTACTAGTAAAAAATTATAGCGACCGACATCTCGCAGGTTGTTAAAGAAAAGTGCATTGACGGGCCACGCAACCTTGGCAGTTTATATCTCGGCTGGTTTTGGTTTTATTGGTTAAAAAATTTCTGACGAAATAAGTTTGTATCACTTTTTCTACTAAAAATTTGCAAACACTTTTTGCTAGCAGCGATTAACCGAGATATTACCGGAAAAAGTACATGAGTAACATGGTGCATCGACAACGAAATATCTCACAAAACTCTGGCAGGTTATATCTCGGCTGGTTGTGGTTTTATTAAAAAATTTAACAAAATGTTTATCCTCTTTTCTACTACAACGCAGTTGAACACTTTTTGCTAGCAGTGATATAAACTATGATCGGAAAAAGTTAGATGAGAATCATGGTGCATCGCCAAGAGATATCTCACAAACTTTGGCAGCTTATATCTCGGCTGGTTGTAGTTTTATTGAAAAATTGTTAATTGACAACATATTTTTCCTTTATTCTTTTGCCACAAATTTGCAGATGAACACGTTTTGCTAGCAGCTATAAACTACGAGATATGATTGGAAAAAGTTAAATGGTAGATGCATTGATCAGCTATCATAGCTCATGTTTTACTTATCTCAGGTTTTACCAAAAAATTGCCAATTATTAAAACATTAGCCTTTTTCTTCGAAAATTTTGCTCCCCCGAATTGCCGAAAATATCCTAGATTTGATATTTTTTTGTAGATTTAGGAGCCTTAACATTTGTTAATTTTTTAAGTATTGACCGTTTCCTTTCAAAAATAACTAATCTAATACTGAAACACAGTTAACTTTTTTCATTTCAATTTTTATAATTAGGTTTGAAAATTGCCGAAAACACTGTCGGCATTCAGTTGGAATTTTGGCAATTGCCCCTAGGAATATTTCCGATTCCCACGCGCCCCTGGTGTGAACCTAGTGAGCATGAAGCCAAACGATTTAGAAATCCAGCACAAATAATCCTAGCTTTTTACTATAAACAATCTAAAAGACCTTACCACCAACGCCGTTTCCGTCTTCAACAAAGACTGCAATCCTCTCTGGTGCTGATAAATTTCCATGATACCAAACTTTCCCCACAACATCCTCAGTTACAGTAGGCGCTATTCGACACAAATGACTGTCGATGCAGGGAACCTCAATTCGTCGGGGGCGCCGGCACCGTAGATCCATCGAAGACTTGAAGCATCGCCTGTGAAAGTGTTCACATTGATCGGAGTGGTAAGGACGGCGATGAGTTTGGGCACATCCTCGATGAACACCACGTGGCATCGACGATCCGTTCCATCCTTGTTTTTTGCAATGTAGCCGAACATTAGCTCCGTGTCCGTCCCCTTTTGGCCTTGGGCTCCGAGTGAGAAGAATGAGAAGGGATGACGTTGAATTAGACGACTTTGTTTTGAATGATGATTTTGATCATTTTCGCGAGCAGGAAATGTTGATGTCTACGGTTTCTGGAAGTTTTCTTTTTTCACTTATTCACCGAGGATTACCTGAAAAGATGGTTTACCTGGGCTTTTTCATGGACCCGTGAGGTTGTCGGATGCAATAATTTTGTGGAAATTAGTGAATATCTCTACTTTTATGACTAGCGGCTTACATCATTTAGCGCGATTTTGAGCGACCTGTAAGATGTCGGTTGCTTTAGTACATTCTAGTGGCAGGCTTGGCTGAATTTTACTGGATATATAAGCTATCAAAATTTGAGCATGTCGATGCACCATATTATCTCCTGAGTTTATTTCCATGCTGCTATCAAAAAGTGTTAAAATGCAAAGAGTAAACGATAAATATTTTGTCAACTGACACTTTTTCAAAACAAAACCAAAACCAGCAGAGAAAGTAGTCCAAGTTAAGTCAGATATTTCCGTTAGTCGATGCACCATGAGTAACCTTTCTATAATAACCTGGTGAGATGTCGGTTGCTATAATTTTTTGTCATTAATTTGGACAGCTTGTTAATTTGAGATAAATCTTGATGATATCGTGGCGCGGCCTACCTTTCATATGCGGGTCCTTTTTTTAAACATTTTGCAAAGCTGGTCATGCATTTTTAGTAACACTTACAAATTAATGAGTGTTTTGTATCGTAAATTTTTACCATCAGCCATGCCCAGAAAGGCAACTAGCCTTTTATTTTCTTTTGTTTTTTTATTCCACAAAAAAAAACTCACCCTACTAACAACTGGATTGATTTCTCGAGCCGCAGTCACGCGAACAGTATCTGCAACGTGTTACATTCTCTGAAAATTGATCAGTTACTTACGTAGATTTGTTATATATTTGAGCTTGCAGATGCCTATTACCTGCGTTCATGCCTACTAAGACTACCGTCTGATTTCTAAATTGAATAAGATTTTTTTTTGATTTTAAGCCATAAGAAAAACTAACGAAACAATTCTCATCTCGGAAACCATCACGTTGACTCGACTACTGGATGAACAATGCCGAGGTACTGAAATACAATTTTATATTTTCGGGGAAAAAACTAATAAAAAACTCACAGTAGCCGACAGAGAAACCCCGCTGCTCCGCAGCTCCTCTGCAAATGAGGGCTCCACGTTGAGCATCTCCGCAAGTTGATTTTTCATTCCGACGGAATTCTTGATTATCTTTAGAAAAAATCTAACTCGACATTCGATCCGAAATTTTCCAACGATTGAGTGAATGAGGAACATGACCGGGAGAGAAGAAACGGAGACGCAGGCGGTGAGCGGAGTGGGAGAGAGAGCGCGCGAGACGGAGAGGCGCAGGCAGTGGTAGGGACGAGACAGGGAAAGATCAGATGTTGGCTGATGTAGGTGAGTCAGCATCTAATAAGTTAAGTTGACTCATAACTTTGTTATTTGATCAGACGGGGGGGGGGGAGGCCGTGGCCTAGAAATATCATTGCCTACTTATTCTAACGTCACTAATGGCCTAGGAAACCTTGATAGCTTTTTTGGAGAAGATATGACGTCATCGTGCTGGTGAGTGACTAGAAATCTTATTTTAGTTCTGGAAGAGGACAAATATTCTGACCGTGCAAAACAAATTAATGATGTGACTGGTGGCCTAGAAGTCTCAAATTATACCTGGGGAAATAAATGACGCCACTTGTGGCCTCGAAAACTTAAACTATGCCTGGACGTCACCGGTGACCTAGAAATTTATTTCTGGCCACGTCATAGAAATTTGAATTTTGATGAGAAATATGACAATTTTATTTATGGTTTTCTGAAAATTAGAATTTTATTGATTTTTTGGCAACCGGGAAATTGGAAAATTTAATAATTTGAACAAATGCAAATAAGCAGTTTTTCAACAGTCATTACTTTTTTCCGTGAATTTGATTTTAATTTGTAAATTTAGGTCGGAAAAGTCATACACACCGAGGAGCTTCCCTCATCCTCCCTGGATCAGTCGGTAACTGCGTTTCGACAGTGGGAGTGGGAGGGGTGGGATGAGTTCGATTCTTCTGGAATTCTATAGTTTTTATTTTTGTTTTTTTGCGCCTACATATACCTGTGAAAATTGGAACTCGACACAAAAACCTCTCTAGCGCTTATATTTACTCCAATTCTTCCGGAATTCCATAATTTTTATTTTGCTTTTTTGCGCCTACATATACCTGTTACAATTGGAACTCCGTTTGACACAAGAACATCTCTAGCGCGGGCTTAAATTTACTTCAATTCTTCCCGAATTCCATAATTTTTATTTTTGTTTTGCGCCTACATATACCTGTGAAAATTGGAACTCGACGCAAAAACTCTTTAGCGCGGCTTACATTTACGTTTACAGTCCAAAAAAATCATCTATAATGTTTTTAAAACTAGAATCCAAATCTATCAGATTTTTTTGAATTTTTGATTTTTTTCACATCGAGATTCGAGCGCGGGAAAATTTGGATCAATTAATATTTTCCAGATTTCGATACTCCATATTTAAAGCAGATCACCTGAACGCCAGAATATGATACTTCCTACTCGTCCACCATCTTCGCTTTTGAAAATAAAAAAAAGTCGCCGTATTATATTGATATAGAAAAAATACCAACAAAATTGTTACTATTCACTGATTAGGCATGCAGGGTCTTTAAAGTCAACATTCATAGTGGGAGCTGGAAATACAAACGCATATATAATAACTTGTTAAAAGTAATTTATTGTGGAGTTATAACCTATAGACAATTAAAATAACCTGCTGCCTAAAGAGTAGTTAACAGAAGCAAAGGTTTTCTTAGTGGAGTTTGTCCATTTACTTTTGTGCATGTTATTGAATTGAAATGATACAGTGAAACTAGAGGTAAAATTATTTACTCGGTTTAGGCTTAGGCTCAGGATTAAGGCGCTTAGGCTTCGTTTTAGGTTTAAGATGAGCTTAGAAGTACCGATCGTAACTGATAACTTCTGCAAATTTAGTTTCTGTAATATCGGCAATAGCCAAAATTGCCGGAAATTTCAAGTGCGATTAAATAAATAGAGAAATAAAAATTAGTTCCTAAGATACATTATCTTTTTGCAGTAAAGTAGTAAAACTACTCACGAAATGCGAAATTGCGATGCGGAAGGAAACATTCCTATGGTTCCTTAGACAATTTCTCACCTATTAGGATATAATATATAAATGATGAATTTGACCTTTTGACAATAATTCTCTTCGATAAATGCATTTACTTGTTTTTTTTTTAATGAGTAAAGCAGAGTGTGGAATATACTATGAGGAAGATGGTGAATATTGTTGGAAATTTTTCTGAAAGTTTTCATTTTTTCTGGAAATTTAAAGAGTTGGGTGTAATTACTGAAAATTATGTTTTAAGAAAATTATTTTAATGTTCAAATTTTACAAAGAACTCATTTTTAAATCATTAGAGGTGTAGCCAGTGGGAAGATTGTTGAGAAGATCCACTCCTTACGAAAAGATACGGAATATCATAATAAATCACTTTTCACGCGAAAAGCTATTAGTAACTTTTTACTGTCAAAAAGTGACAACCACTCTGTTTTGGCCACTCATAATTTTGCAACGACCAAAAAATTAAAATTTGTTCTCCTACATTTATTATATACTTCAACTTTGTTTTAATTATTTGTACTTGAAAATTGTAGGGAACAGCATGCGACAATCCTGTCAGTTTTCAAAAATCTCTACTTACAAAATATAGGACACGCTCTAAAAATGGATGTTTTTACATACAACGCCATCCGAAAATCCCTTGTAACGTCGGCACATGCGGTCCTTTATGTGACAGTTGTCGTGAGAAAATTAGAGATAAAAAATGTCCTCAGTGTAATCAGAAAGGCGTTCGTATCGTGAAAGCAATGTGAATAAACAATTTTGGGATTTAATTGGTTTTTGGCAATTTTTAAAACCCCAGGAAATGGAAGTTGAGGAGACTAGGTTGGTTAGAATAGCTCTTTTTCTTTTGGATTTTTCGGTAATTCCGGGACTGCGGTTATCCTTTGGGCCGAAAACTAGGCCTTAGAGCGATAGGACTAAGCCTTAGCCTAAAACTAAGCCTCAGCCTAAAACTAAGCATGAGCCTGAGCCTAAGCCTAAGTCAAGCTCGCGCTAAGCCGAATAAGTCTGCTGCTATCAAAAAGTGTTAAAATGCAAAGTTGTAGTAGAAAAAACGATAAATATTTTGTCAATTGACACTTTTTCAAAAAAAAACCAAAACTAGCAGAGATATAAGTAGTGATGAGTCAGATATTTCCGGTCGATGCACCATGTAACCTTTCTCTAACAACTGTGAGATGTCGGTTGCTATAACTTTTTAGTCATTAATTTGGACACCTTGTTAATTTGTAATAATTCTTGAAGATCGTAGCGGGGCCGACATCATTCACGGGTCCTCTTTTTTTAACATTTTGTAAAGCTGGCCGCATTTTTGGTAGCACTTAATATTACATCAACCATTAATGAGAAAATGTTTTGTAAATTTTTACTATTAGCCATTGCCCAGAAAATGGCAAGGTTGCTTTTTTATTTTATTTTCTTTTGTTAATTCACAAAAAAATCACCCTACTAACAATTGGATTGATTTCTCGACCCCAGTCACGCCAACTGTAGAACGTGTTGTATACATTCTCTGAAAATTGAACAGTTACTTTATTACGAATTTTTATATATTTGAGCTTGCGATTGTGTGATCAAAAATTTTGAAGCATGGTACGTAATATTTGAACGATTTTTTTTCGGAAAATCAATAAATGAAAATGGAGTTTTTTTTTTGGATTTTAGCAGACTTCCCAAACCGATGACTCGGAAAGATCATATGAATCGATTATTTTTTCTTTAATAAACCTGTTCAGGATTTGGCAGGCATTATTATGAGAAATAGGCCAATTAGCCTAGCATGTACGGAAGTAATTTTTGGTAAAACTTTATAAAAGTAATGAAAAGCTGATATTTTCAAAATTCCAGAAAGACGGAAAAATCATATGAATATGCTTTTTTTTTCTTTTTTAAGCCTATTTAGAATTGTCAAAACTACCAGAAAAGACTAAACAAAATAGCTTAAGCTTGATCGGAAATATTACATTTTAAAAAAATAAAAATAATGAAAAGCTGACGAGATATTTCCATTCCAGAATGACGGAAAAATCATAGCGATACTATTTTCTTTTATAAAACTCTTTAGACTTGTCAAAACTAACAGAAAATACTATACAAAGTAGGTTAGCTTAACCGAATTTCTACAAACTGAAATAATAAAAAGATGATTTTTTCAAATTTCTAAAATGACTGAAAAATCCTATGAAGCGATTCGTTTTTCATTCATAGAATAGTTTAGGACGAATTGGAATCATGATCAGAACACATAAATTCGCAAAGTAGGTTAGCTTGACCGGAAGTATTTTTGAAAAAGTGAAAAAACTGATTTTTAAACCAGAAGGACGGAGAAATCAGATATGCAGCGATTCTTCTTTTATAGAGTAGTCAGAATTAGCATTATTATGAGAAAATCGCGAATAAGGCTAGCATGTACGAAAGTATTATTTAAAAATTTATAAAAGTAATGAATAGCTTCGGATTTTTTAAAAATACCAGAATGACTACGGGAAAACTCATATCATAAGAACGATTCTTTTTTCTTGTATAAACCAGATTTCAGAACTGACAAAACTATTAGAAAAGACTGAACAAATGAGTCCTAGAAAAGACTAGTTAGGGAAGAATTCTTAAAATAGGAAGTTGACCAGAAAATCTGGATCTGAAATCTGGAAAAAGTAACTCTCAAAAATTCAAATTTTGATTTTAGGAAGATATGGCTGTGTAGTCTTCATAGACAATCAAAATAAATTCTATTTTAATTTTCAACCATCTTTATGCACGGGCTGATTCTGTCCTTCCTCATTGAATTTTTCGCGCTCCATTGACAATCGCCTGCCACAACGCGTGGGAAAGTCGTGTACTGCACACGGACAAATACATTTAGTTTTACAACTGAAATCGAGCCGCGACGCGAACACGCAACGCGCCGTAAATCTACCCCACGGTAAAGCGCGACATGAACTAGTTCAAACTCTGCGGTCCATTTCAATTTACGCGGAAAGCCAGAAACCCCAGTCGTTTTTATGTAAAAGTTCATACTGAGCAGTTAATTTAAACAAATCAAAATTTGGAAAATGATTTTAGGCTTTGTGCAAACTGTAGCGTCTCACGCGTAAAAATCTGCCAATGAATAAAAAATTTCTTTTAAAATTTTTATAACAGTTATTTGCCCAACTTCCGTTTTTCAACGTTAATCCGTTTCCAGTGATCAAATGCTTACACGGAAATCACTGATGACGTTCCATGTTTGGTTGCGATGTGAATAAGGTCGTTTTTTGCCCGAGAAAAAATGGTCACACGCACACACACATAGCCACACAAAATATAATTTGTATATTTTGTTTGATTCGAGTAAAAAAAGAGAACAGGTATTCCTGCGGCGTCGTTTTTCTAAACCGCAAGAAAAGATTGAGAGAAAGAAAGAGAAAGAAAAAAGATGGGAAAAAAACAGTATAAGGGATAAAAGTGTTTCTGGATTAGGTTTAATTATTAGGGGCGCACCATATTGTCGTAGAGGTAGGGCCCTTTTCCAAAGTTTTAAGTTTAATCGATAGAGCGTGAATACATAAAGAGAGATATTTGACCTGCAAAAAAAATATATGGTTGGTTTCTCATGCCATAAAAAAAATCCATGCAACAAATGAAAACTACACCTGCCAAGTGTCTCCGCCAGGCTAACCTAGTTTTTCCCTCCAAATGTTCCGTGACTGTTGTTTAAGGCTTTGCAGACCGCTTTCCCCACCGCACCCGTGTTAATCTATTCCCGAAGTGTTCTCCCTAGATAATCGGGTTGCACATTTTTGGTGAATCGGCTGGGGGTAATGAAACGGAGTAATAAAATAAATGAATAAAAAAGAAACTCCTTGTGGAGAGGCAATGAAAAAGCAAGCTATGCAAAGTATTGATCCGTTGTTATGAATCTTCTGGGCTCTTAGGCTTAGGTTTTTTTTAGGTTTAAGGCTTAGGCTTAGGCTTAAGCTGGCTTAGGGTTAGGAGGCTTAGGCTGAGGCTCAGGTTTAGGCTCAGGCTTCGGCTTAGGCTGAATCTAGGCTTTGGCATAGGCGTGGCTTGTGCTTAGGCTTAGAATTAGGCTTAAGCGTGGGCTTAGGCTTAGGTTAGGCAAGCTTAGACTGAGAAGACTTAGGCGTAGGCTTAGGCTTAGGCTTAGGTTTAGGCTTAAGCCTATACCTAGGCTTAGCCTGGCTTAGTCTTAGGCTTAGGCATCTCATGTTTAGGCATTTTATGCTTAGGCTTAGGCTTAGACCATGGCGTGGGTATATCCGAATGTGTGTTTTATTATGTTTCTGATTCTGAAATCATTTGTTATTTTAATATCCTACCAACAAACAAGGTTGTCTCTTTGTGCTGCCAGGTGGCATTTCCTTAATCATCTCAAATATTTTTGGTTTCATTTCCCCCCATCGCAAAATCCCTTTCTTTATCTGTCATTTCGCCTCTACGTTCAACTTATTTGATTTTGTGGTTTTCAAGAGATCATCACGATTAAACAACGAATGAAAAAAATAGGTATGGAATTACTACCGTATTCTTTTTTGCCTATCCTTGTGTCTCTCATTTTCCTTTTCTCTTCTAACCAGTTCTGCATTTTGGAATTTCTTCTCCGATTTGATCAGTTAAAGCTATTCGGTTTAAACCATCTTCTATTCAATTCTGATGATTACTGTTAGGAACGAGTGGTCACTTTCAAAAGGTCGAACTGTTGTACTAATTGAATTGGAAAATGCTCGGTATTTGACGTTTATCAGAGAAAAATTGAAGATTTGATATAAAATTTTGTAAAAATGAAAAATAAAGTTTCATTTAGAGTAGTATTCTGGCTTGCCTTATAAATTGTAATGGAAGAGTTGGCCATATTCGGCCATATCTGGGGTAGATTTACGGTTCGAGCGTTGCGTGCACCATCGCGTCCGGCTCGATTTTAGTTGTAAAACTAAATGTATGTCCGTGCGGAGTACACGACTTTCCCACGCGGGTCCGGAAGGCGATTGTCAATGGAGCGCGACAAATTCAATGAAGAAGGCCAACTTAGTGTAGTATTAGCAGACCAGGTTTTCACATAATTTGAGCGGTCTAATGCACATTTTTACGCAACTTTATGGGCCAGTATAATTTTCTTGGAAGTTTTATTTGAAATAAATTCAAATATTTTGAAGCCTAAAAATAATTGCCAAAAAAACAAATTTTTAGTAATTTAACTGCCTCTAAGAGTAATGAACAAATGTTTCCAACTTTTTGCAAATTACTTGCTAAGTTCCCGTGCAAATCTTGTATATAGATTTTGGCCTGAAACATAACAAGCCGATTGTTACAAAAATTAGGAAGGTACAATAGTGTGTTTATTGATCAAACATGTGTTCTTGAAGTTGGGTAAGAACAATTGATGAAGGTTTGGACCAAAGGAAAGCAAAAAATGTTTTTAGAAGTGAAAGTCTGAAACATTACCTTATTTCTGATGGTCGTTAATCAAATTTTGACAGACTGTAATAAGAAACCTTGGCCATCGTATTTTCTTATTAGTGCAACCGACCACTTTACTTTGAGTAAGACGTTCTTGTTTATTGCCTTTTAAAGACCTCAATATTTTAATAACTACACAATCATAGAGAACCAACAAAAATTTTGTTAGTTGACAAATTTAAATAGGACAAACGATAAATGAGCAATGAGCTGTCAAAGTTGAACAATGGTGGTGCAATAGAAGGAACTACTAGAAAAAATACGGGTCCTAAAATAGTTTTTATGTTAAAATCAGAAGATTGGTGGGTTGATTCCAGAAGTTTATTTCAAAATATAAGGTAACTCCGCTGACCGCGCCTCCGGTACCTTCAAAAGGCAAAAAGTAAGACTTTTCTAAAACTACAGTTATCCTACAGTAGGTCCAACAGTACACCTACAGTACCTCTACAGTATCTTGACATGATCCTCTACCTACTCCGAACCCAGTACCTCTTCAAAGGCTAAAAAGTCAAAATTACACAAACTACAGTAATCTTACCGTACTACAGTAAACCCAGTGAACCATTACAGTTTGACATTATTCGCCACCAACTCACCCTAACCCAATACCCTTCAAAAACTAAAACGTCAAAACAAACTTGTAACAGTAATCCTGACACCGTACTCCTACAGTACTCATACAGGACTACTACAGCGGACCCCAAACATATCTCACTAAGCCCCAAGTCCAGATCACTTTCAATGAAGTCAATTTTTCCAAATGTAACTACAGTAATCCTACAGAACTCCTACGGTACCCCTACAGTACTACTATAGTACCCTGACTATGTCTTCGACTAAATCCAAAGCAATATCCCTTCAAAAGACGAAAAGTTAATCTAAAACTGCACGTTACGGAGTCTTCCAGTACTCCTACAGTCCCCTACAGTACTACTACAGTACCCTGACTATGTCCTCCACTAACTTCAAATCGATAACCCTTTTCAAAAGACGAAAAATCATGTCAATTTTTTCTTTTTTTTATTTGAAATTGTCCGTTATTGCCATTATGTAATTTTCCAAAAATGCTGCCATCCTAAAAAACTGTTAGGTTTTTGTTCATACACATTTAGCTTATACACCACCTGCATAGTGACCCATAAAGAACCAACTTGGCCCCTGCCATACTTGGTATACAAAAATCGAGAACATTTGGCAAACCTGAGTGGTCATTCTATTAGCTATTCACCATGTGCTCTAATAAAGTAGAACTGATCATGGGAATATGTGTCAAGGCAGTAAATGGGGGAGTACTGTTAATGTACGTGTGCAATATTCCAGATGCCAAGTATACAGAGTATCTAATGACGGTAATTTGATTTCAGGTGCTTTAGTACGCTATATTGTTCCAAATGCATGATATTTTTTTTTCGAAAATTGAGGTTTTGTGTCGAATGTCCCATAATTTTGGATAATCAGTGGTCTTTAGCGAAATCTTGAAGCCGCTTAAAGCAGTGCTATATTTACAACTGCATTAGCGTTTTATTTTGCTCTGAAAATGACTGCAAATACACAAAATTTTGGATTAAACCGCCTGATTTTAAAACCGAGCTTAAACAGAATTTTTATTTTACAAACCTTAAAAAGTCCAAAAATTTTCTAAATTCCCTATACTAAAATTTAGCGACCCCATCACTTTCTACCCCTTAATTAATTTTTTACTCCATTTAAAAAAAATATTTTGAACCGGCAATTGTCAGAAAATTGGTTGCCTATTCCCGAAAATTTCCAAAACCGGCAATTGCCAAATTTTCAAAGCCGGCAACTGTCAAAATGGCAGCAAACTTCCAAAACCGGCAATTGTAGAAATTGCCTATTGCCAATAATTTAAAACCGGCAGTTGCCGAAATTGCCGAAATTGCCGCAAACCAAGACAGGCAATTGCCGAAATTGCCGGTTCGAAAATTTTCGAAACCGGCAGTTGCCAAAATTGCCGCAAACTTCCAAAACCGGCAATCAATAGCCTAAACCTTTGCCGATTGCCAAAAACAACACCGGCAATTGCCAAAATTGCCAATTGCGCAAAATGTTCAAAAAGATTTCAGAAATTGATACGTTTTATGTCCTTTAATTGTTGTGGGATTCTTTTTTAATAGATTTGAAACATATCATCCTGTTTTCAAGAAAATTAATTCCTTCAGTTTCTGACGACTCAAATCCTCCGCAAATGCCAAATTTATTTTGGGCAAACTAAACCAATTCTCAACAGAATTTTAGAGGTGGAGTATTGCCATTTGGTCTAAGTACACTTATAATAATCCAAAAGAACAGACTATCATGAAAAACACTCGAAACAAAATTCTTTTGGGCGACTTCCAAAATTATGAGTGGCAAAAAGGCTGTGTAAGTGCCACTGGGAATTTTGATGACAGTAAAAACTATCAATTTCAAAAAAATTTTGGAACGTTTTATTATGGTATTAGGTTATTTTGGGAACAAGTAAGTGGTTTACTCCACCTTTAAAAATTTAGCCGTTATACAAACTCCAACTATATCCATTTGATACTTTCCCCTCTACCCTACCCATAACAACATAACAGAAAAATTGCTTGGGAAATTACGCATCGTCGCAGTACACCACACTCCATTTGGATTGATGTCCCGAGAGAAAGGTCAAATCGTATTCTACCTCCTTATTCTAACCATCTCTATTATATCATGCTTTAATGAACGAGCGCCGCCGCCGCGCGCCTAGCGCCTCCGAGTATCGCAAAGTGCGACTTGGTCTGCCACATAACCTGAATTCTACTTTGTTGTATGATAGAATCGGATAGATGTAATGTGTAACAATAAAAAACCACGACGACGACTGAATATGGAATCGGCTAGGTGGTACAAAAGTTTCGGAATGTTTTGGTACCATGGTATGTGTAAGCTCTGTGAATTGAGCCACGGTCTAGCAACGATATTTCGTCGAAACTTTATTCTCGAAAGATTGTTCAATTGAAATTTTCCGCAAAAAACATTTTTTGAAAATATTTTTTGCTAAAAATGTGAATTTCTAGTGCAGCATTTTTTTTTTAATATGAAGTCCAATCAAAAAAAAATCTCAAAGAAAACATTTGAATTTCCCGGAAACCCCAATTTATGAGAATCAGTTTCCCTTTAAAAGAAAATTTCGGAGAAAATTTGAAATTCCGCGACGCCAAATAATTATTTTGAAATATTATTTCCTTATCGGCAAGTATTTTTTTTTTTGAAAACTTTGATTTAACGGAAAACCTTCTGAGAATTTTTGAATGTCCAGTTTAAAGAAATGTTCGGTCGCACGGGTTTCTGGCTTCCCTCATAACTTGAATGGAAGAGTTTGCCAAACTAGGAAATTTGGTTCGGCTATATCTTGGGGGGTAGATTATTTACAGCGCGTTGCGTGTCGCGTCGCGGCTCGTTTTTAGTTTTAAAACTAAATGTATTTGTCCGCGTGGAGTACACGATTTTCCCACGCGTTGTCCGGCAGACGATTATCAATGGACCGCGCGAAAAATTCAATGAGAGGAGGCCAGAACCCCGTGAATTCCAGCAAACCAAAACTTGAAACTATTTGAAATACCCACAAAAAACCACTTTGGCTGAGAATGTTTGAATTTCCACAATTTGACGGAATACTTGAACAGATTCAAAAAATTTTGTGAGAATAGTTGAATTTCAAAAACCTGTTTTCTGAGAGTTTTGGACAAAATCCCTCAAATTTCGGAAAAAATTTATTTCCCTCAAAAAATTTCGAGAAATATTTTAAATTACCGGCATATTTGACATTTTGAACCCCACGAAAAAATTTTTAAAAATTTTCGAAATCCCGGAATAATTTTTTTCACTATAGTCAAAAAAGATCAACTGACTACTTACAAACTCCAGTACCCAGAGCATAACCCCCATTAGCTTCCGATTGCTACAGTAATTTCCTACAGTACTCCTAAAGTCCCCCTTCATAACGTTCCCCTGATAAATGCCCTTTAAAATATGCGTATTATCACATCTCACATGATTAAGACTAAAAGGGAGAGGTGTACCTTCAGATAAATACCCGTTCAATGTTTTTTCCTAAACCAGTTGACTTATAGGTTATGAAGAGAAGACTTAGTGTAAACAATGTCGTTGGAAGTGATATGTTAAGAAGTTAACGGCAAAATCGATGCCAAAACTTTTTCAGCTTTGACTTCTACTGCACAGCTCATTCCATAACCATGAGCTCACGTGCCCTTCCCCCCCCCCTCTATCTTCCACCGCACTTTCATTCCTCGTTGTGGCAACAAACCCATCTCCGGATTCGCCTTAATATTTGTCACAGCACAGGAGTACACTCCTTAGCGGCCAATTCGTAATAGCGTCTACCCAGCGACTTGGCCCAGAAACCTTCCTCTAATCGCATCCACAATAAAAAGGTCTGCAAGTACAAGATTAGCACCCCCCATTGATGTCAATTTATCTATTTTGATTCCATGGAACTATTCCACAATGTAGAAAATTGGGGTTATGGTAATCGAAACATGGTGGATCACCTAACTGCTGGCCAAATCATCATGGTGTCAAAAATAAGAATCCGAGTCCTCCCAGACATCCATGTAGGGTATGCACTTTCCCGCCTGTCCCGCATCTAACCTAACGATTAACATCTTTACAGACCATCTCTCCTCCGGATGATGTTGAAAATGTCGCGCCAGCACCTTTGGAGGCGGGGGGGGTTAAAAAGATTCCAATCAACCACCTATCTTCTCGATTTATCATCAAGTTTGCCCCCCGCGCTCTTAGATTAAATGAACTCTTTTGGCTCAATCACAGCACTTGTTATTAAATCTAGGAACTGCATCTATTTCGAACATTGTATCGTTACAGTTACCGAAAAATGTTGAAAATTTGGGAAAAGTGCCAAAATGTTGATCAAGTCAGAGAGATTCGAAGACGCTTCTAGCAATTTTTTGACAGTACCTGTCCCCTTTCGGTAGATTTGCGGCAATTCTCGGCAGATTTACAGCCGCTTTTGGCGGTTTTGCAGGTCAACTTTTAGCAATTTTGGCAATTTGAAAACTTCTACTTACTTTGCATTTTAGTCAATTTTCTGTAATTTCTGAGAACTTCAGATTTTCTTTTACATTTTTTTCCGATGCACCATGTCCTGAACGCTCGCGCCACGACTTTTTATTCATTATAGCAGGTCCTGTTTTGATGCATCATTTCCCAAGAGCCCTGCAATGCTGGCGATTCATGTCGCGATGTACCATGTCATCAAATGTTTGCACCCACTGCACGTTCCACCGCAACGAGGTTTTAATGCCAAATTTTCTGCAATTGCTCGTCAAAATATTTTTCGACAATTTTGTTAGCAAATTTTTCCCTTGCAAAAAGGTTCAAAATTCTGTTCCAAACACCAAAAAGTCGAAGATCCGCAAAATCTGCACTTGAAACACTATTTTGACAACCCCCGTCTCAGCTTGCTATCAAAAATGCAGCCAGATATATGGGCAGCTTGCATGTGAAACAAAAAAGAGAACGAGAGGCATCAGGGGCTAGTCCTCAAAGTAGATGTGCAACTCTATGAAATCGATACGGTTATGCATGGCATGGTGACAGGGAGCGAAGTATGATGATGATGATGATGGTGGAGAGAGCGCAACGTATGGTTACTGAATGTTTTCGATAAAGGTTATCTTTATGGGGGGGGGGGGGGGGGGGGTTGGGGCAGTGTGCATCGAAATATAAAAACTTTCGTGGAGATACGCTTTTTCAAGAAATTTGTGACACCTTCTTGGTGCATCGAGACAGTTTTCGTGGCAAGACCTGATTTGGTTGAAACTCTGAAGCCAAATCGCGGTCTACGATTTTGTGACCAGGTCAAGGTTTTCGTGGCATGGTGCATCATAGTAAAAATTAAAATCCTGGGAAAAAAAGCTCTATATATAATAGCGAGCCATGGACCGTACCTCCCGCGTGGCCCCCTTCTGGAGCTAAAAAATAATTTTTCTAAAACTACCGTAACCAGACTACAGTATTCGTACCGTACCACGATATTGTACCACTACAGTACCTCGACGCTATATCCGACTAACCCCAACTCACTATTTATCCAGAAGCCAGAAATGTGACTACAAAGACTACATAGATTACAAACTATGAACACACGTTGTGAATAAGCGCTTCACATAAATAGTGACATGATGGATTATTGAGATCCCATATGTGACATGGTGCATGGTGACAGGCATTCTGGGAGGGTGAGCACAAAACAAAATCATTAGTTATTTTTCGCCGACAATTTCCAATACAGCGAACTTTACCAAGGTCGTGGCCTACTTGTTTCCGTTACAGTTTCCTATTGTTGCATATTATACCGCCAGTAATCATTGCGTTATCACAGTTGACAACGGTTTGATAATGTCACAAAGTGTGGGGGTTTTGGAACAACAAACCAGCATACGATTATTAGAACGTGATAATTATTTTACCTGAACATCAAGTATTATTAGGTGGTGGAGCTGGGAGCTTAGTATTTGGGTTTTGAAACAATGCACCATGTCCTAAAAGATGCTTTATTGCTAGGTAGGGTGCCGCGACTGTATCCATTCCTATAACAGGTTCAGTTCCGATGCATCTGCTATGAATTAATACTGTTCTTATTCTTAGCTCAAAATCAGGCTGAGGCCCGCAGGCCCGAACACTTTTGGAGACTGTGCAGCTTTAATCCCCAAAGGCAAATTGTTATTCGCTCAAGCCAACTCATCTCTCCAGATTTCCACAAACTTTAATCACTCATATCTCTCAAAACCCTAGACTTCGATTTTTAATCCATAGTCGATCCCAATTTTTAAGGAAATCTCGAATATCCCTAGCTCAGGTTTGAGGCGAAGCAGCTGAAGCTACCTTTTTGGGCATCCCCATTCCAGAAACAGACGATAGCTGGCGTGGCCCTGCCGAGCTCGTCATTTGCCAAAACGTCAAATTGCTGGATCATGTCACGATCCATAATGCCTTGAACGGTTCTTCTGCACCTAAAATTAGCACTCAACTGGTTGAGGTAATACATGATGCAAGACCATGTCCCAAAGGGTCCTGCCATGTTGGGACATGTCACGATGCACCATGTCCTGAAAGATCCACGCTGGAAAACTACATTGTTCCGAGTGTTTACCTCTATTTCAATACGAAATGTCAGCAAATTTTCATCCAAACTCATGTCATTCAAACAAGAGCCTCATGTGACTATAGGGTCGTGACTACCTGCTCGAGTTCGCCTCAGCCCTGTTTTCAGAATAGCTATGCGTTAAGTACCCGATGTATTGCAACTGTCACGATTTAACGCTTAAGTTTTGTAGTTTTGATGGAAATTTTTGAGTTTTTCGTTTTTTCTTGGCTCAAATCTGGGAGAGTTTTGCTTTTTTGACGATTAAATATTTCATAGGGCAGCCCGGCATTTCTTGACTGATTGTGCGACATGATGGTGACAGGGCTTAATCGTCGCGAGACATCCCTCTAGTACAAAATTCTTTTAATATCAGTAAAAGCATTATAATCCATGTCTATACTTATTTTATGGAATTTTCATTAAAAAAATCTGAAATTTACGAGATGATCTACTCCAATTATAGATGGGTTTCAATCCAAAATTTCTCAGAAAAACTAAAATTAATGGGCATAAAAATGTTTTGTCTGAAAGCCCTAGATTGTCAAATATCCCTAACACCCCAAAAAACACCAATGTACATCTCCTCTCCGTAAATATGTAGTTTTACAACCGCCTCTCTGTTGACTGGGAGCCATAAATGTAGATATATTATCTTTCCAGATCGCCTGCCGGCCCCTCCCACCTGATTGTAAAACTGCTCTTTGCTGTGGCGGTTTATCGACTTGTTTTTCTTATATATTCCATTCTACATGCACCTTAACACATTTTCTTGTTTCTATACACTTTTTTAACTATAAAAAAATGCAACTCCTTTTCGATTCACGATCTTTTTATGCAAATCTTTTGGCTTAAAGCTGGAGTAGCACCAGTGGGGAAATTGTTAAAAACCACTCCTTTGGTCCGAAATGTACTCCGAATATCATAATAAAACTTTTCAATATTGGAATTTTTTTCTTCACAGTCATAAAGTGATAATTACTCAGTTTTTGCCACTCATAATTTTGGAAGTCGACCAAAATGTTTTTTCTAGATTTTTTATAATGTAACTATTTTGTTTTAATTATTTTTATGAAAACATTGGCATAGAGACAGGCGGGCCAACATAAGATATTGCTTTGCCTCAAAGGCTCATATTTTTCAGAATTTTGGCAATTTGCCAAAACTTGGTATTTAAAAATTGTTAGAGATAACTGTATTTAAATTGCAAAACATAGAACAGTTGTATTTCAAAATAGTTCGTAAAAATTGTCTAGTTTATTTTGCGGCCACACTGACCCCCACGATGCACCAGGACAAATTGCATTTTTTTGTTCAAAAGCTATTGTTTTGCAAAGGGGCATGTTCCAAACATCTGACCCAAGTTTTCCCGTAGTTCTTCTCTCCCCCAGCGGGGTAAACACTGCACTTTACGACTCCGCCCAGTTTTTTTTTTCGCACAAAGTGAGAGAGAAAGAAACATCACTGCGTCACTCTCCCCCAGTCTTACGCTCGTTCCCGCCCCCCTCCTCGATCTGCAAGCCAGACCGTCCTGATGATTCGAGGAGCCATTCCTTTTCTTATATGTATACGTTTTTGGAGAGGTGATCTTGTTTTTTTTGTTTCTCCTTTCGTTTTGTTCTCTATGCTCTGATAAGAATTTTGTTCTCCTACTTTTCTACGGTTTTTTTTTTTATATCCAAATTTTTGAAATAGAGGGTTGATCTACATGACCCCCATGCTTAGTCTACTATAATGCTATATCTGATATTCCGAATGGCTGGTAAGTGAAGGCTTTTAGCCCAGTGAGCCGGCTTACCAAGTCTGCCTAAGGACCATGGTTCTTTCAACTTAAGGCCCAAAATAAGCAGGGATTCTGGCCTAACCCCCACTAAATCTGTAGGCTAATATATAATTTCTATCATACTCCATCCTTCTTTTCTACCTCTTATCATGTTGTTATTGAGCAGCAACCCTTATATTGTTTGGTATATAGATTTGATATAAAACCTCGTAGTAAATTTTATTTTACACAACAATCATTTATCATAATTTTTTTTCATACTATTTTTTTGCAGAACGAAAAAAAAATGCTATTCACAACATCTTGAGCACTGGAGCTGTTATCATCAAAAAGGTGCATCGCAGCACAGCGGGAGCGTGTCATCCGATCAGTTGCTCAAGGCTTTCGGCGAGCTGGAACTTCCACTGAGCAGCTTCACAATGACAACACAGCAGCCCTGTACCACTCCTGTGCAACATTTCACAACACCCAAATTACAGACTCCAGTCAAACTCACCGTGCAGACCGTGTCGACGTGAACTCAGAGCCACACTCTTCAAATTGTCATCACCATTCATTTGAGCATCCGATATGCGCGAACGCTCCGCGGCCGATTAGGAGTCAGCGAACGCCGAAGGAAGACTACCACACTGTACGATCCGAATGAGCTGGAGGAGTCTATGAAGCAGAGCGAGGCGTGCATTTTGGATATCAAGACATTCATCACACAGTACTCGTTGCGGTAGACTACGGTAGTAATGATGACAGGTTAGTTCCCAAAAAAGTGTAGTGGAAGATTTTTTCTAAAATCTAAGCCGTGACCCGCGGAAATAAATCAGAATACATCCCCGCCTAGTTACCTAATCTCTGGTGTTAGCCACAGTGCAATTGTGTATTACTGTAATTCCTTCTATGACGTCATATGAAATAAAGTTGGCTAAAGGGAAAAGGGGACTCTGGATCTTAGGCGAGCAATTCTCTGCAGCCGGCACCAGAATCGATCCCCCGGTGCCTGGATATCTATCCTTCTGGGCTATTAGCCACTGCGAAATGCCCCACCCGCGCTGAGATCGAACAGGCGTCTGAATTCCTAGGCGAAGTTGCTACCCGCGCCATGTAAATCTCCCAAATTTCCAGGAGTAAGCCAGCTGTACATTTCAAAATTGCTCAACGGCAACCACCGTGAACTATCGCTCCGTCGCCGTAAGAACATCTACGGTTGGTACCTGAACTGCCGACGTCATCCCAACAAACTCGCTACTTTCCTCGCCATGTCGATCCGGCTACTCGCCTCGAGAATGGAGATGTCGAGCTGATCCCACAACGTCGAGAACGCTACGTGTTTCGTCCAAATTTCTTCTGATCCGAATGCTAGAATCGTTCTTCACACAAATGCCATTAGATCTTCCACGGCGAGTCTTACGAAATAGCGAATGCTTGCACTCACGTTCTGATGATGGATAAGAAAGGTGTTGGGTCCATGAGGCCAAAGGAGGAGGTTCAGCAGCCTCAAGTGGTTTCGAATTGGTTTGCAAATAAGCGGAAGGGAGTTGAGAAGCCAGAAAGTTCCGCTGAAGCTTTGGCCGCCTCCACCTCGTCAGCTTCGTCTTCTGCGTCATCGACATCATGATTCTGTCAGGGTGTCATCAGCATGAGCCCTCGCGAAAGAGGTGAGAGTTTTAATTTCTCGGCCACGCTGTACTCTGGGTCGAAGAATTTTTTGTAGGTCTGATAAGGAATCCACTCCGGTTTTCCCACACGTTAGGTCATAAACATGTACCATCTAGAGGTACTTAAACTTCTGGACTTTTATTTACTTTAGAGTATGGTAAACCTGTCAGTCCTTGTCAATCATGTGTCTGTTTGGTCTCAAGTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTCGGTCTAGGTCTAGGTCTTGGTCTAGGTCTAGGTCTAGGTCTAGGTCTTGGTCTAGGTCTAGTTCTAGTTCTAGGTCTAGGTTTACTAGGTCTGAGTCTAGACACAAATGTCTAGGCCACGGAAATTTCTGCCGTCGCCTAGGATTTAGGCCATATTCTAGGCCATGATACAAAAAACTTTCCCTGTCTCCTCTGGAGTAACCCATTTTGAAACAGACAAGCTCCCGTAACACAACCCCGGACAGCAATCTCCCCGTCTCCAGCAGTGTCCACTTTTGAAGTGTCCCGCCCGTATGCCATCATCTCTGCCATGTCATCAACAACCTCGCCAATCTCAATTCCAGCACAATCATGATCCATCAGTATCGCCGCCAGCTCTCGAATTTTTCGCCATGGCCCAACGGCTTGGAGTTCAGATTCGGTTCCATTTCCGACATTGCCAACACACATTTTCCCGTTTCAAATGGCCCCTACGGGAACCCGGCTTCTATTTTGAAGTCTGAGTTAAGCATTTCTAATTTTCTTTTCCTCTTTTACACCAATATCTTTTTTCCATTTGTTCTTATTCATCCCATGACAGAAAACCTCATTCTTTCATATTACAGGAATAACGATGCTCCGTTTCTTACGCCCTGCAGTCCCCACACACCCGTCGTCGTAGCAAAAATCACTCAATAATCGATAGGTTTTTCATAATATTTACTTTGTTTCTTTCTTAGTGTGTTTCACTGCTGTTTTAATATTTGAAAAGTACGAGTCTTCAAAAACTCTCCATTTTTTGTGAATAATATTTGCAATCCACAGCGTAATTCGTAATGTATCGCTTGCCCTACGACGAAATTTTATTGGAAATTCCATTTTTTGTGCAATTTTTGTTATTTTTCAAGCGAGAATAAATATTTTCTCGTTCTAGAATTCAATTGTGAATTACTTTGCAAACGCGCCCCATTGCACTTCCGGGTGAAACAAGTTCGTGTTTTCAAGATATTTTAAAAACTTGAATTTGGAACAACACAGAAATCTGGAAAATGCAACAGTGTTCCAAGTCTTGTCCACGTGTGATACGAGTACACAATAATTTTTCATCTATACGGACAGATTTCAAAATTGGAATGTTTTCCATTTCGTGTGGTTTCTAGGCCATGGGAAAACGAGCTAGCGGCCATCAAAAATTCCAGGTGACCTGGAAGTTCTAAAACTTTGTAGAAACTTGTCCACGCGGAGTACACTATTGAATAGTTTATCAATAGAGCGCAAGTAAAAGGATAATCGAATTTCTTGTCCTTTCGCCACCCCCTCTCCATTATATATGAGGTTTTTTCCCTCGCAATTTCCCACGCTCAAGAGGGTCGCCGCCATTTTTTTTTTGAGGGGGGTCGTATCTAGATTAAACACGTTCATTTATGCTCAAAATGTGCCAATAATTTTTGTTTTTGAGTTTCTAGGCCATTTTGGTAAGTTCGCACACTGACTTTACGACTTCCAAGGAAATGGCCAACGTTAGCTTATTTTTCTAGGCCATATAATTTTTTGAGTTGCAACTGTGGCCAATGTTTTTTTTGGGTTTCTATCACTTGTGAAAAGTTAGGTCATAGAATAACATTACAGTAAACGGGTCCTCAAGGGACAATCAGGAATTGTAGCCTAGTTTTCCTAGACCACATTTGATTTTTGTCTTTCTAAGCCTGGTTTGGGTCTAGCTCTAGTCCTAGGTCTAGTTATAGGTTGGTCTATGTCTAGGTCTAGATCTAGTTCACATGAGAAACAAGAATTAGGCCACCTTCCCCCTAAACTCTATTATCTCCAAACTACTACTTTCTAGAAAACTCTAAAATCATAAAACCAATTTTTTATCACTATTTTCATGCTAAAATCCAATCAGAAATTTGATCAGATACACGCATATAAATATTACGACTATAAATTCGTTTCTTTTTTTCATTTTTCCCTCGATAAGGCTCTCGGCGAGAAAAATTATTTCTTCTTCTATGTGTCGAGACATGTGATATTCCGGCCGGCGGTGGCTCTGAATCAATATTCAATTGAGCGAGAAATATATATTCTCTCCAGAAGGCGTTTATATAATGTGTTCCTCCTGTAGTTTCTGCTGTATTCGGCGGATTTGGTATGCTTCTCAGTGGAGTGCAGTTGCAGCATTTTTTTTCTTTAATACTAACTTTTTGTCAAGTCTTTTTTTGGGATCCCTAGAACACTAGAATTTCTCGCTATTTTGAGATTTCTAGACCATTCTTGAGATTTCTAGGTCATATTGTGAGTTCTAGTGCATTTTTGGGTTTCACGGCCGAATTGGAAGTTTGAGGCCATTTTTCGGTCACATAGGCCACGAATTTGAGGATTTTGTGCCAAACTGGGATTTCTAGGCCATCATGGGATCTTTAGGCACGAGTTTTCCAATCATAATATAATTTCTAGGATATCTTGAACCTGTATTCCTAATGCCACTTTGGAATATTAGGCCATCTTGGGACTATTTCTGCCATGATTTCTAGGTTAATAACTGGCAATTTTAGATTTGGGCTTAATCTACAGGAGGACATACTGCGAATTATACACGAGCCCACGGTTGGATATATAGGCTATCGTGGGATATCTACGCCGATATGTATGGAATCCTAGGCCAACTTAAAATTTCTAGGCCACTTAACCCCGGGATTTCTAGGCCGACCATCACGCCTCCTAAAAGGCACAGACGGAAAGTTCAACACCCACCACCAGGATAAAAGTGTTCGTGAATTAGTCAGCAACACCCCATTTTTCTTCTCCAAAAACTAAAAAAAAAGATACCCCTGACAGATATGGGCAGAGATGAGGGTGCGAATCCTGAAATTGCCTAGAATTCCGAGCTTTTTGTGCCAGACAAAGTAGAGCAATGGAGAATGTGTGTCGCCACTTCAAACACCATTTTGTCCGTTGCTTCGCCCGAAGGGCCCGAAAATAGGCTTGAAAAGCTGTGGCCTAGAATTTTTTCTCAAAATTTTTGACGTGGAAAAATTGCTTAAGATTTTCGAGGCCAAGAGGTGGCCTAGATTCAACATTTATTGGCAATTCTTATCTAGATCCCGAACCCCGACCAGCCAGTTTTTAATTCTCCTCCGGTGTCTGAATTTTTAATTAGAAAAATTATTTTTGGTTGAGGAGCTCTGTTTTTTTTTCGTCAAAAATTGAAGGTGGCCTAGCTTTCTCATTTTAAGGCCACGAATTCTAGTTAATTTTTTGTTGGCTCATTTTTTGTTTCAAAAAATGAACCAGTTAGTCAAAAAATTCTTTTCTGCATATCAAAGGCCACTATTTTTGAGGTTCTTTCCTGCACAATTTTTCGAAGAAAATTTGAATTCCGGAAAGTTTTCTCAGAAAATTTGAATCGCCGCCAAAATTTTTCTCTGAAAATTTGAATCGCCGCCCACCCAAAATTTCAGAAACCGTATTTGAATTCCTGCAAAGTTTTCAAAATGGGGTCTCACCACAGAATGGTGACAGCGCCCACATTTCTCAGAGACATTGGTTTTTAGGCCAAAAAAATAGTTTTTTTGACAAGACAAAAACATAGCAAACACTTGAGCAGTTGTCATATGTCTGTTGCAAGTGGAAAAAATAAAACATCTTTCCTTTTTTCTGCTTCTCCCCCTCCGTCCTTTTTGGGCTCAAAACTCAAATGGGTTGCTCATCTCAATTGTCTGACAAATTAGCAAAAGATGAAGCAATTTTTCCCTGTTTATCTTTTTTTGCCTCCGTTTGGCTCCTATGTCTTTTTTAGTAGTTTTCAGAGGTTTAATATTGAATGTTCAAACTGGCTAAAAAATTTCGATTTTTTTTTCTTTCTAAACTCTTACGAAAATTCTGATATAGGTTAGAAAATTTGCCTTAAACAGATCGACGGCCGACAGCGTTTACATTTGTGGCCTAGACTTCCAAGCCTGGGCCATGGCAAAAACTTGTTTAACTAGCCTACCTTTTCAAATAGTGGCCACTCTAAACTATTTCTGAACTGTTTACTCAAAAGAGAAAGTTAGTGGCCTAACTTTCTCAATGGTGGCCTAGAAAACTCCAATTTTGGCATTCATGACCGGTCATCAACCTGACATTGATGGCCATGCTAAAAAGTTAATGAGTGGCCTAGAAAACCAAAATATGGCCATGCGCTCAGCATGTTTCTAACTTTCCAACTCTGCTATAAATTCCTTGGGGGAAACCTCGGCCATCACGGGTGACCTAGAAAACAGAAATTCGGCCAAGACCCCGTAATTCATGGCCTAACCCTTTAGACGTTTGACTTTGGTGGCCTAGTTTTTTGTGATGGCTAAGTTTACAGAAAAAATCCTCAGCCACAACCTTTACCCTATACATGACATAAAAATGTCCATTATCCAATTAAATTTCCAATTCTCCACCCTTAATTTTTCATTTTGTTCTCTTCTTTTATTTTGTCACTCTCTCATTCTGAAACTAATCTTTTCAATTCTCAGTTTTTCTGGTGTGGTTGATTTTCACAGCTTTGCTCCCGCCATTTTGCAATAGGATTATCCGTGACACAGGCGCTCACATAGCTCAGTGAGCAACACCAACAAAAGCATATATAGATATACAACGATATCTAACTAGTTACACCGGAGCTTCTGTTGTTCTTGCCCCTCCGAGCCGAGACAAACTTTTGGAAAAGAGCTAAACAACGCTTCTGGAGCCGACATATTCGAATGGAAAGAGACAATTGCGACCACTATGAGGAAATGATGGTCGAGGAGGAAATGAGAGATGGCGTAGCTCAAATTGCGCGACGAATGCTCCAAGTTGGTCTATACGGTAATCAGTGAGTTTTTGTGTTTTGTTGGCCGTAGTAGAGATAACTAGGCCAACTAGGTAGGCTGACGATCTTCAGTTTGCAAATCCTCTTCAACCGTACTTTTTTGAGCGATCTAGGTTTGCAAAAGGTAGGCCGCCTGGTCCACCGTACCTGTCAACTTATGATGGCAGAGGTTTTGTCTGGGAAAGCTAGGCCACCTGTGTGAGCTCATGGTCCAAGGTCTAAAGTTTACAAAAACTCTTCCACCGAAACTTCTAGGGTGCTCACGACCGAGGCTTGCAGAAAGGCCACGAGACTTGGCTCGTGGCCCAGAATTTTACTCATCCATCGTAAATTATTAGAAATCCGCGAGGAAAAAGCTAGGCCATCAAATTACCTTAGTGGCCCAGAATCTATAAAAACTATCCCATCGTAGCCCTCTTGCATGGACGGCTGAGCTGAGGTAGCTAGGCCCCGAGAATAGGCCAGTGGTCTCGAATCAACACAAACTCTCCACCGTACCTCCTACAATGGCCGAGGTAGGGAAGATGGGCGCCAGGCTAATCTAACTTTCCTAGACTGACCTAAAGGGGAAAAAACAAGGCCACCGGGTTTACGGAGTGGCCGACTGCGAAATTTCACAGAGACATTGCCCTGACTATCTGACTGATTTTTTACCGTCGAAAAATTCATATTTTCTATGCCAGGGGCCCCCTACGGCCCAATCCTCGCAATTTTTTTATGCAGATATCTAAAATCGCACATTTGTTAAAGCTCTGCACACTAATCAAACTTCTCGTCTGCTGGTGGGCCGTTGCTCCGCAAGTCAACTCCTACATGACGCACAGTATGGGGAGCAAGAGTTCATTGGCGCGAATTTGTCAGATCCAGAGAAAATTCAAAACTTAAAATTAGCAGATCTTAAAATGTGATTCTCTAGGGAGCCTCCCGCTTGAGGCCGTGGACGCTGTAATTTTCGATATCCGACTTTTCCATTACCTATGGGGCATTCGAGGATGTGTGGCAGATTATTTGGATGGCGGTGGGTACTGTTAAGTTTCCCTACGAATCTATACATTTTTCAGGCTTCGGGCGACTTTTGTGGTGCGTTTCCTGCTTAACCCTGGTTTTCTCCATTCCGGTCCTCTTCATCTCCCATCCGAAACCCTGTCTCTTTCGGCCGCTGCTTTTTCAGGTGAGTTGGCTGAAAAAATTTGGAAAAAAACTTTAAATTTTATCCGAAAGGCGATAAGCAGTGGGATTTTCCACGACTACCACTCACAACAGCATGGTTCGACCCAGTCCGCGTGGGTGTGAATTATTTTTCTAGTTTTTTTTTGAAGTACGGAAATTGTATTTAGCCTTATCTGAAAAATTCTAAAATATGCAAAAAAATCTCCGATCAAACCAAGTAGTATCCTTCTCCAAAAAGCGCAGCAACGTCAAATGGTCCCACGTGGGGCCTGAATAACGGCAAATTTCCTGACAATTGACGGGTTATCATCCACCACCCTCATCCTCTTGAAGGAACATTGACTTTTTCCGTTGAAATGGACAAAAAAATTGAAAAGAATTAGATAGATGCGGGAGAATGAACATGGTGGCCTAACGTGGTGCTTGACCCATGGGCTAGAAAACCAAAACTCAGTCATCACCCTGATTGAGGCCATGAGATTAAGCCACGTACGACGCAATCCTAGGCCACCACGTTTTCTCGGCCACAGCCACCCCAAACAAAAATCTGAACTTTCTGATCCTTTCCATCTCTAACCAACGTTTGTTTATCTTTTTACTCGCTCCACAGGAGCAGAACTTTTTTCTATTTTGAAATCCACAAAAGAATCCGGGACAGACACTAGTGTATTTTGTTTTTTATTCAGCCATGAGCACAGACCAGAAATAGGATTGTATCTCGGACTTCAGAGCCTGGAAAAAATCGGAAAAAATCGGAAAACAGTGGAAGAACTGAGTTGGGTGCTAAATTTGGCAACTTGCCAAAATTTGGGGATAACTTTTTCGGTAATCTGTAACTACAGTTTTCCTAAAAATGTATGAACCTTTTAGTGATTACTGCATAGTTTTTCAGGTCTTTAAAAATGAACCTACAGTAGCCCGTACAGTTCACAGGATTGCAAAATTCCAAATTGACCACTTTTTAAGAGTGTATCTCGGCAGAGTATTGGGAAAGTATCGGAATATTTTAAAAATTTTGGATAATTTTTTTTTTATTTATAATTAATTAACATTTAGCTTTCAAAGATGAGCAATGTATTTATAGATACCCATGCAACTTTGAAATAGTTTGTATATCCGTTCAGTGTAACTATCAAAAAATTTTCAACTACAAAATTACTTCATAGCAAAATTTAAAACAAAGAAATTGTTAGTTACTTTTTAATAAAGTACAACCGAGATATTTGTCAAAGTTGAGCTACTTTATCGGCAACCATAAGTAGCCCCCGTACAATGCACCATGTGGTAGAAAATTTCGGTTTGATCTACTTAAATCTACAAAAAGTGCGGGAAGTCGGAGAGTTTGGATAGCTAAGAACGTGCTGAAGTGTTTGCACATTTTGTTGGGCACAAAATTCCCACTTTTCTGATTGTAGATCAAACCGTCGCGGGACAAACTGGTACCTCTTCGTTGTTGGTATGTAAATTTTGAAAATCACTTCGTTTGGTTGGTATGAAACTTTAAACTAGAAAAAGCCCTAAAAGTTGAGCTAGGCGCTCAAATTGGGTAGCATTTACTTTTTTCAACAAAAACATTGCTGGCCGAGCTTTCTTTTACGGCCACGTTGCAATAAAAATCCAGGAGGACCATGTCATCAACAAAAGTACAAGGATGTAGCATAAACAATCACTCCGAAACTTTTGTCGGGCACTGCTTTATCGGAAAAAAAAAAGGATCTCTCCGAACACATCGGTGTCACCCCCAGGGTTCTATAGCGTCTCCCTGACCTCGCGAGCTATTTCCTCGAGACAAATCTCTCTGAATCCTTTTGTAATGGTTGTTTCATGTTCTTCTTCATCTTCTTCTTAGGCTATTCTTCGCTGGGATAAGTAGTAGAAGAAAACCAAAAGAACACATAAAACACAGGCACACACACACACACATTCACACCGTAATATCATATAAAAGTGTGGCTGCGTCTCCCAGAGCGCCCTGGGGGTAAGCAACGCGGGCGCCCGCAAGGAAAAAGTGCAAAGAAATTAGAGAAAAAAGACCGTCTCACTCACTTCTCGATGCCTTTTCTTCTCTAACTATAAAAATTGTCAACTGTGGGGCCTCGAAACGAACGAAAGCGAAAAAAATCAAGAGAACTAGACTCTGAGAGAGAGACAGAAGAAAGAGTTTTTTTCGACGCCGACCGCAGCTGCCAAGCAGCAATAATGACATGCTGGAGAAAAAAATTCAAAGTTTAAATATGTTTTGGCGATCAGAAGCCTAGACCATAAGCCCCTTGTATTGAGTTTTCTCGGCCATTTTTGGTACGGTACATATACATAGAGACTTCAGATTGGGAATTGCGAATCTGTTAGAGTAAGAATAGGCCTAAAACATTGGGCCTAACGGTGACGGAGACTAGGCCTTGTTGGGAGCGATTGTTAAACTATGACATTGCCTAGAACCTCGTTCTATCTTGGTTATGTGGTGTCGGGCTTTCATGATCAGCTCCTTTACTTTTGTCCAGAGAAGGTTTGGGCTTTTTCTGTGGGTGCTTTGGGCTCTATTGTAAATAGGTGATCTTGCGCAGAACACAACGTAGATCTAAATTCTTGTCTAGGCTCTGCAGGCTCCTGAGGGTAGCTGTTTTGCACCCCAAAGCAAAATGATCTCAAAATTACACGACTTCAAGCAGGAGGATTTTTCGATGATTGCCAAATTTTGTAACTTTTATAGGCTTAAGCTTATGGTTATGTTTAGGCGTAGGCTTAG 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+V 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
--- /dev/null
+@SQ SN:CHROMOSOME_I LN:1009800
+@CO Test supplementary reads, for CRAM
+supp 99 CHROMOSOME_I 100 1 50M50S * 0 0 TAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTACCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCC *
+supp 2147 CHROMOSOME_I 200 1 50H50M * 0 0 CCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCC *
+supp 2195 CHROMOSOME_I 500 1 50M50H * 0 0 TTTTAGTGAAGCTTCTAGATATTTGGCGGGTACCTCTAATTTTGCCTGCC *
+supp 147 CHROMOSOME_I 600 1 50S50M * 0 0 TTTTAGTGAAGCTTCTAGATATTTGGCGGGTACCTCTAATTTTGCCTGCCAGCCTAATACTAAGCCTAAGCCTAAGACTAAGCCTAATACTAAGCCTAAG *
--- /dev/null
+@HD VN:1.4 SO:coordinate
+@RG ID:UNKNOWN SM:unknown LB:UNKNOWN
+@SQ SN:CHROMOSOME_I LN:1009800
+I 16 CHROMOSOME_I 2 1 100M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PT:Z:27;28;+;STOP;Note=tag1
+II.14978392 16 CHROMOSOME_I 2 1 100M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PT:Z:27;27;+;PRIM;Note=tag2|28;28;+;OLIG;Note=tag3
+III 0 CHROMOSOME_I 2 1 27M1I73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTCAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA ###########################"##@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PT:Z:1;1;+;COMM|101;101;+;COMM
+IV 16 CHROMOSOME_I 2 1 100M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+V 0 CHROMOSOME_I 2 1 100M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+* 768 CHROMOSOME_I 2 255 1M * 0 0 * * CT:Z:+;STOP
+* 768 CHROMOSOME_I 28 255 2M * 0 0 * * CT:Z:+;COMM;Note=consensus%0Amulti%09line%0Atag%0A!"#$%25^&*()_+<>?:@~{}%7C%0A1234567890-=[]'%3B#,./\
+* 768 CHROMOSOME_I 101 255 1M * 0 0 * * CT:Z:+;STOP
--- /dev/null
+@HD VN:1.4 SO:coordinate
+@RG ID:UNKNOWN SM:unknown LB:UNKNOWN
+@SQ SN:CHROMOSOME_I LN:1009800
+I 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PT:Z:27;29;+;STOP;Note=tag1
+II.14978392 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PT:Z:27;27;+;PRIM;Note=tag2|29;29;+;OLIG;Note=tag3
+III 0 CHROMOSOME_I 2 1 101M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTCAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA ###########################"##@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PT:Z:1;1;+;COMM|101;101;+;COMM
+IV 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+V 0 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+* 768 CHROMOSOME_I 2 255 1M * 0 0 * * CT:Z:+;STOP
+* 768 CHROMOSOME_I 28 255 3M * 0 0 * * CT:Z:+;COMM;Note=consensus%0Amulti%09line%0Atag%0A!"#$%25^&*()_+<>?:@~{}%7C%0A1234567890-=[]'%3B#,./\
+* 768 CHROMOSOME_I 102 255 1M * 0 0 * * CT:Z:+;STOP
--- /dev/null
+I 4 * 0 1 * * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+II 4 * 0 1 * * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+III 4 * 0 1 * * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+IV 4 * 0 1 * * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+V 4 * 0 1 * * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
+VI 4 * 0 1 * * 0 0 ACTAAGCCTAAGCCTAAGCCTAAGCCAATTATCGATTTCTGAAAAAATTATCGAATTTTCTAGAAATTTTGCAAATTTTTTCATAAAATTATCGATTTTA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
--- /dev/null
+@HD VN:1.0 SO:unsorted
+@SQ SN:CHROMOSOME_I LN:1009800
+@SQ SN:CHROMOSOME_II LN:5000
+@SQ SN:CHROMOSOME_III LN:5000
+@SQ SN:CHROMOSOME_IV LN:5000
+@SQ SN:CHROMOSOME_V LN:5000
+@SQ SN:CHROMOSOME_X LN:5000
+@SQ SN:CHROMOSOME_MtDNA LN:5000
+@RG ID:UNKNOWN SM:UNKNOWN
+@PG ID:bowtie2 PN:bowtie2 VN:2.0.0-beta5
+SRR065390.33808391 4 * 0 0 * * 0 0 GATCGCACTGAAAATCTGGATATAGAACGTGTGCAAATGATTGTCTCTACCGTTCCGTAAAAATTATTGCTAATTAGCAATGATTTTAAGCTAATTAGTT CCCCCCCCCCCCCCCCCCCACCCCCACCCCCCCCCCCCB;CCCAACCCCCCCCCCCCCD=B9BCABCBCB>BBBC@B<<@BA;BCC?B>A<<@(?:4==4 YT:Z:UU
+SRR065390.33808433 4 * 0 0 * * 0 0 NCATCTTCTGCAGGCGCGGTCGGCACCGTGTATTCGTTACGTTCCACGCCGATGATATTAGACACCAGCACGGTGTGATGCGCAGTCACCGCACGACCCG !################################################################################################### YT:Z:UU
+SRR065390.33808462 4 * 0 0 * * 0 0 NGTTTGAGCGCAATGACTTGACGATGACCGGTGATTACAGTAACCAGCATATTGTGCCGATGAAGCAGGCTGTCGCTCCGCAATTTGAAGAGGGACACGA !################################################################################################### YT:Z:UU
+SRR065390.33808468 4 * 0 0 * * 0 0 NGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACTTTATTTTACTCTCTGTGGCTTTATCGATTATTTTTTTCTCCTTGGCTTTCCTCTTTATTTTT !))))))''&585555AAAAA6AA############################################################################ YT:Z:UU
+SRR065390.33808471 4 * 0 0 * * 0 0 NCGTCTTCTGCGGTTTCTATGATAGAGCAATTCTGTGGCGGATATTAAGATAACGGGTATCTGTTCTTTAATGATGCCGCAAAAAATGGAAAGTTAAGAA !################################################################################################### YT:Z:UU
+SRR065390.33808489 4 * 0 0 * * 0 0 NGGAAATTCTGCGGTATCGAGAGATATTTGCCTTTAATTACCCCATAGCCGATTAACATCCCGGCACTATTAATCATTTCAATATTATCAATCACAAAGT !################################################################################################### YT:Z:UU
+SRR065390.33808504 4 * 0 0 * * 0 0 NTGGAACACCATGCCCACTTTCGCACGCAGCAGGGCGATATCCTGAGAGTTGGTCAGGATGTTGTCGCCATCAAGCAGAATTTCACCTTCCGCACGCTGC !################################################################################################### YT:Z:UU
+SRR065390.33808511 4 * 0 0 * * 0 0 NCAGAAATATATTGAACTTTTGAAACATGTCCCAACTTTTTTTTTTTTTAGAACACGTTGGCTGGTTTTTCAAGTTTTGAATACTTTTTAGGTTTTTTTG !***()(+++AAAAAAAAAA:78:8318::AAAAAAAAAAAA########################################################## YT:Z:UU
+SRR065390.33808521 4 * 0 0 * * 0 0 NTGTCAATACATTGTAAGGATTTCCCATTATGTCAATACATAGATCGGAAGAGCGGTTCAGCAGGAATGCCGAGACCGATTTCGTATGTCGTGTTTCTTT !################################################################################################### YT:Z:UU
+SRR065390.33808523 4 * 0 0 * * 0 0 NTACTTCTTACAAGATTTTTATCGCTACTTGAAAAAAATTCATCAACATAATCGCCATGACTATCTGCACCGTGAGTATGATAAGCAGCAACTCTATCTG !***+--,')AAAA778577A72AA50888AAAAAAA72A88858AAAA77AAAAAA7AAAAAAAAA8AA############################## YT:Z:UU
--- /dev/null
+@HD VN:1.0 SO:unsorted
+@SQ SN:CHROMOSOME_I LN:1009800
+@SQ SN:CHROMOSOME_II LN:5000
+@SQ SN:CHROMOSOME_III LN:5000
+@SQ SN:CHROMOSOME_IV LN:5000
+@SQ SN:CHROMOSOME_V LN:5000
+@SQ SN:CHROMOSOME_X LN:5000
+@SQ SN:CHROMOSOME_MtDNA LN:5000
+@RG ID:UNKNOWN SM:UNKNOWN
+@PG ID:bowtie2 PN:bowtie2 VN:2.0.0-beta5
+SRR065390.14978392 16 CHROMOSOME_I 2 1 27M1D73M * 0 0 CCTAGCCCTAACCCTAACCCTAACCCTAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #############################@B?8B?BA@@DDBCDDCBC@CDCDCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:1 XM:i:5 XN:i:0 XO:i:1 AS:i:-18 XS:i:-18 YT:Z:UU
+SRR065390.921023 16 CHROMOSOME_I 3 12 100M * 0 0 CTAAGCCTAAATCTAAGCCTAACCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA ###############################################???88:;98768700000<>:BBA?BBAB?BBBBBBBB>B>BB::;?:00000 XG:i:0 XM:i:3 XN:i:0 XO:i:0 AS:i:-6 XS:i:-13 YT:Z:UU
+SRR065390.1871511 16 CHROMOSOME_I 3 1 100M * 0 0 CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA <?@<@A8>0:BB@>B<=B@???@=8@B>BB@CA@DACDCBBCCCA@CCCCACCBCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:0 XM:i:0 XN:i:0 XO:i:0 AS:i:0 XS:i:0 YT:Z:UU
+SRR065390.3743423 16 CHROMOSOME_I 3 1 100M * 0 0 CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA ##################?6@:7<=@3=@ABAAB>BDBBABADABDDDBDDBCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:0 XM:i:0 XN:i:0 XO:i:0 AS:i:0 XS:i:0 YT:Z:UU
+SRR065390.4251890 16 CHROMOSOME_I 3 1 100M * 0 0 CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA ###########@BB=BCBBC?B>B;>B@@ADBBB@DBBBBDCCBBCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:0 XM:i:0 XN:i:0 XO:i:0 AS:i:0 XS:i:0 YT:Z:UU
+SRR065390.5238868 16 CHROMOSOME_I 3 1 100M * 0 0 CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA @,=@@D8D;?BBB>;?BBB==BB@D;>D>BBB>BBDDB<DABADCACDCCBCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:0 XM:i:0 XN:i:0 XO:i:0 AS:i:0 XS:i:0 YT:Z:UU
+SRR065390.6023338 0 CHROMOSOME_I 3 1 100M * 0 0 CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAAGCTAC CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC@CCDDDBCCABB=DABBA?################ XG:i:0 XM:i:3 XN:i:0 XO:i:0 AS:i:-6 XS:i:-6 YT:Z:UU
+SRR065390.6815812 16 CHROMOSOME_I 3 1 100M * 0 0 CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA ###############?@.@?B;B0B=;<DADB@@BDDBBDDBCBCBD@CCDCCCCCCCDCCCCCCCCACCCCCCCCCCBCCCCCCDCCCCCCCCCCCBCC XG:i:0 XM:i:0 XN:i:0 XO:i:0 AS:i:0 XS:i:0 YT:Z:UU
+SRR065390.6905811 16 CHROMOSOME_I 3 1 100M * 0 0 CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA #######################BB@>A<BC>@@BCCB@=BACBCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC XG:i:0 XM:i:0 XN:i:0 XO:i:0 AS:i:0 XS:i:0 YT:Z:UU
+SRR065390.8289592 16 CHROMOSOME_I 3 1 100M * 0 0 CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA ###############################A?@C9@@BC=AABDD@A@DC@CB=@BA?6@CCAAC@+CCCCCCCCCCCCCCC@CCCCCCCCCCCCCCCC XG:i:0 XM:i:0 XN:i:0 XO:i:0 AS:i:0 XS:i:0 YT:Z:UU
+SRR065390.33808391 4 * 0 0 * * 0 0 GATCGCACTGAAAATCTGGATATAGAACGTGTGCAAATGATTGTCTCTACCGTTCCGTAAAAATTATTGCTAATTAGCAATGATTTTAAGCTAATTAGTT CCCCCCCCCCCCCCCCCCCACCCCCACCCCCCCCCCCCB;CCCAACCCCCCCCCCCCCD=B9BCABCBCB>BBBC@B<<@BA;BCC?B>A<<@(?:4==4 YT:Z:UU
+SRR065390.33808433 4 * 0 0 * * 0 0 NCATCTTCTGCAGGCGCGGTCGGCACCGTGTATTCGTTACGTTCCACGCCGATGATATTAGACACCAGCACGGTGTGATGCGCAGTCACCGCACGACCCG !################################################################################################### YT:Z:UU
+SRR065390.33808462 4 * 0 0 * * 0 0 NGTTTGAGCGCAATGACTTGACGATGACCGGTGATTACAGTAACCAGCATATTGTGCCGATGAAGCAGGCTGTCGCTCCGCAATTTGAAGAGGGACACGA !################################################################################################### YT:Z:UU
+SRR065390.33808468 4 * 0 0 * * 0 0 NGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACTTTATTTTACTCTCTGTGGCTTTATCGATTATTTTTTTCTCCTTGGCTTTCCTCTTTATTTTT !))))))''&585555AAAAA6AA############################################################################ YT:Z:UU
+SRR065390.33808471 4 * 0 0 * * 0 0 NCGTCTTCTGCGGTTTCTATGATAGAGCAATTCTGTGGCGGATATTAAGATAACGGGTATCTGTTCTTTAATGATGCCGCAAAAAATGGAAAGTTAAGAA !################################################################################################### YT:Z:UU
+SRR065390.33808489 4 * 0 0 * * 0 0 NGGAAATTCTGCGGTATCGAGAGATATTTGCCTTTAATTACCCCATAGCCGATTAACATCCCGGCACTATTAATCATTTCAATATTATCAATCACAAAGT !################################################################################################### YT:Z:UU
+SRR065390.33808504 4 * 0 0 * * 0 0 NTGGAACACCATGCCCACTTTCGCACGCAGCAGGGCGATATCCTGAGAGTTGGTCAGGATGTTGTCGCCATCAAGCAGAATTTCACCTTCCGCACGCTGC !################################################################################################### YT:Z:UU
+SRR065390.33808511 4 * 0 0 * * 0 0 NCAGAAATATATTGAACTTTTGAAACATGTCCCAACTTTTTTTTTTTTTAGAACACGTTGGCTGGTTTTTCAAGTTTTGAATACTTTTTAGGTTTTTTTG !***()(+++AAAAAAAAAA:78:8318::AAAAAAAAAAAA########################################################## YT:Z:UU
+SRR065390.33808521 4 * 0 0 * * 0 0 NTGTCAATACATTGTAAGGATTTCCCATTATGTCAATACATAGATCGGAAGAGCGGTTCAGCAGGAATGCCGAGACCGATTTCGTATGTCGTGTTTCTTT !################################################################################################### YT:Z:UU
--- /dev/null
+>CHROMOSOME_I
+GCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGC
+CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCT
+AAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA
+GCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGC
+CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCT
+AAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA
+GCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGC
+CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCT
+AAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAAAAATTGAGATAAGAAAA
+CATTTTACTTTTTCAAAATTGTTTTCATGCTAAATTCAAAACGTTTTTTT
+TTTAGTGAAGCTTCTAGATATTTGGCGGGTACCTCTAATTTTGCCTGCCT
+GCCAACCTATATGCTCCTGTGTTTAGGCCTAATACTAAGCCTAAGCCTAA
+GCCTAATACTAAGCCTAAGCCTAAGACTAAGCCTAATACTAAGCCTAAGC
+CTAAGACTAAGCCTAAGACTAAGCCTAAGACTAAGCCTAATACTAAGCCT
+AAGCCTAAGACTAAGCCTAAGCCTAATACTAAGCCTAAGCCTAAGACTAA
+GCCTAATACTAAGCCTAAGCCTAAGACTAAGCCTAAGACTAAGCCTAAGA
+CTAAGCCTAATACTAAGCCTAAGCCTAAGACTAAGCCTAAGCCTAAAAGA
+ATATGGTAGCTACAGAAACGGTAGTACACTCTTCTGAAAATACAAAAAAT
+TTGCAATTTTTATAGCTAGGGCACTTTTTGTCTGCCCAAATATAGGCAAC
+CAAAAATAATTGCCAAGTTTTTAATGATTTGTTGCATATTGAAAAAAACA
+TTTTTCGGGTTTTTTGAAATGAATATCGTAGCTACAGAAACGGTTGTGCA
+CTCATCTGAAAGTTTGTTTTTCTTGTTTTCTTGCACTTTGTGCAGAATTC
+TTGATTCTTGATTCTTGCAGAAATTTGCAAGAAAATTCGCAAGAAATTTG
+TATTAAAAACTGTTCAAAATTTTTGGAAATTAGTTTAAAAATCTCACATT
+TTTTTTAGAAAAATTATTTTTAAGAATTTTTCATTTTAGGAATATTGTTA
+TTTCAGAAAATAGCTAAATGTGATTTCTGTAATTTTGCCTGCCAAATTCG
+TGAAATGCAATAAAAATCTAATATCCCTCATCAGTGCGATTTCCGAATCA
+GTATATTTTTACGTAATAGCTTCTTTGACATCAATAAGTATTTGCCTATA
+TGACTTTAGACTTGAAATTGGCTATTAATGCCAATTTCATGATATCTAGC
+CACTTTAGTATAATTGTTTTTAGTTTTTGGCAAAACTATTGTCTAAACAG
+ATATTCGTGTTTTCAAGAAATTTTTCATGGTTTTTCTTGGTCTTTTCTTG
+GTATTTTTTTGACAAAAATTTTTGTTTCTTGATTCTTGCAAAAATTTTTC
+CGTTTGACGGCCTTGATGTGCACTACCTTCGCTTAAATACTACATTTTCT
+GAAAATGTTATAATAGTGTTCATTGTTTCATACAAATACTTATTTAATAG
+TATTTCTGGTTATATAATTTGTATAAAAAGTGGTTGACATAACAAGGCTG
+ACGAAACTTTGTGATGGCTGAAAATATTTTCCTAGCTTTATTGATTTTTA
+TTTATACGTGTTTGAATAACTTGGCCAAATCGCCGAGAAGGAATAGAATA
+CTGGACGACATTGTACATATTTTCCAAAAAATCAGAAAGTAGATGACGGG
+ACCAATTCTTTCTGTCAGGTTTTACAACCGCCCAGTGCGTCTACGTCACA
+TGTTGTATAAATGGTTGTAAACAATATGCGGAAACAATCAAATGCATTCC
+CATAAGGCATAATATAGAGGCTACAGGCAATGAGTATCGCTCTTTGCTTT
+GTTTAAAGGGGGAGTAGAGTTTGTGGGGAAATATATGTTTCTGACTCTAA
+TTTTGCCCCTGATACCGAATATCGATGTGAAAAAATTTAAAAAAATTTCC
+CTGATTTTATATTAATTTTTAAAATCCGAAAATCCATTGGATGCCTATAT
+GTGAGTTTTTAAACGCAAAATTTTCCCGGCAGAGACGCCCCGCCCACGAA
+ACCGTGCCGCACGTGTGGGTTTACGAGCTGAATATTTTCCTTCTATTTTT
+ATTTGATTTTATACCGATTTTCGTCGATTTTTCTCATTTTTTCTCTTTTT
+TTTGGTGTTTTTTATTGAAAATTTTGTGATTTTCGTAAATTTATTCCTAT
+TTATTAATAAAAACAAAAACAATTCCATTAAATATCCCATTTTCAGCGCA
+AAATCGACTGGAGACTAGGAAAATCGTCTGGAGATAGAACGGATCAACAA
+GATTATTATTATATCATTAATAATATTTATCAATTTTCTTCTGAGAGTCT
+CATTGAGACTCTTATTTACGCCAAGAAATAAATTTAACATTAAAATTGTT
+CATTTTTGAAAAAAAAATAATTAAAAAAACACATTTTTTGGAAAAAAAAA
+TAAATAAAAAAAATTGTCCTCGAGGATCCTCCGGAGCGCGTCGAATCAAT
+GTTTCCGGAACTCTGAAAATTAAATGTTTGTATGATTGTAGAACCCTTTC
+GCTATTGAGATTTGATAACTTTTAAGTAATAAAATTTTCGCAGTAAGACA
+TTAAAACATTTCACAATTAAGCTGGTTCTGAACTGTGTGAAGTATATTGA
+AAAAAACTAACTGATACAAAAATATAATTTTATGATAGTTTTCTGGATGT
+CCCAATATAAACGATGTCAATTCTGCGACATGCTACAGTCATCCACGAAA
+GTAACCCGAATACCGACAAAAGAAGAGGAACGCCAACTTTGGATAGACGC
+TCTAGGGGCTGATTTTGGTCGGAAAATAGTCGGGAAAAAATAGAGGACAT
+TACAGATGAGGATGAGGATGAAGATAGAAATTTGCCGACAACTTCGTCAT
+GCCGCTGATTTTTTTGATGTTCTACGCTTAAATTTTCAGCGAACGAACTA
+TTTTTTATATTTTGATTGTTTTTAAATAATATTTGCCATAAGAAATTCTC
+ACTTTTCCAGGAAACGTCGTTTCGCCGCGATTTTCCTCGTCTCCAGTCGA
+TTTTGCGCTGAAAATGGGATATTTAATGGAATTGTTTTTGTTTTTATTAA
+TAAATAGGAATAAATTTACGAAAATCACAAAATTTTCAATAAAAAACACC
+AAAAAAAAAGAGAAAAAATGAGAAAAATCGACGAAAATCGGTATAAAATC
+AAATAAAAATAGAAGGAAAATATTCAGCTCGTAAACCCGCAAGTGCGGCA
+CGGTTTCGTGGGCGGGGCGTCTCTGGCGGGAAAATTTTGCGTTTGAAAAC
+TCACATATAGGCATCCAATGGATTTTCGGATTTTCAAAATTAATATAAAA
+TCAGGGAAATTTTTTTAAATTTTGTCACATCGATATTCGGTATCAGGGGC
+AAAATTAGAGTCAGAAACATATATTTCCCCACAAACTCTACTCCCCCTTT
+AACAACCACCCGAGGATATATTCGACAAACGATCTATCTACTAGGAATAA
+CTCGATTATTGACATATTATAGACTTCTTTTAGTATTTGTAAAATAGAGG
+ATCAGACCCAAAATTCAGCCCGCGAAGGCATGACGTCAGCGCGAGGCAGT
+AGTTTCCAGAAGAACTCTGTCGTCTACCTTAATGCCTCAAATGCGAACCC
+GCTTCGGCCATCCTTCTCGCTCAGAGAATGGATTAGAGTTCTCATCAACT
+CCTCTGTCTAATTTTCAACTGCGGCGGTTGGCGACCGGTATTACCGCGGC
+GACCGACACCTCCCGGGTTCCGTCGATCGCTGTCTGTTGTGTGCGCCGCG
+ACTCCGCCCACCGGTGGTAACTTTTTGTGGGGGAATCTTTGTTTTTGGTC
+ATTTTTCAGCGCTTTTCAGCGATTATTGACCAATTTTGAATAAAATTTTC
+AACAGAATATCATCTAAAATATTGCTTAACATTTATTTAACAGAAATAAC
+GTGAGCACGCATGTAAAACATGAAATTTTCGGGAAAATTGCAATTAAACG
+AATAAAAATCGATATTTAAATCAATTATTGGTGAATCCGGTGTGTTGAGG
+CTTCAATGCATACATTTTTACTGGATAAATCTCCTTTGGGAATCCGGTTT
+GCAGTGCTTTCGAGACCATGTCCAGTTGAGAATCGGCGAACGCTTTAAGA
+AGCTCGGGCTGAATAATGAATTGTTTTAAAAAATGTTTAGTAAAAAATTG
+TTTTCGTGCAAATTGTCTTCGATATTATCCAAACGTGACGTTTTGCGATT
+TTCGCGCTAAAATTACAGTAAGTGGGGTCTCGACACGACAATTTTTGTGA
+AATACAAACGGGCGTGTGTCTTTAAGAAGTACTGTAGTTTAAAAACTTCA
+TTTCTGTGGAATTTTCATATATTTTTCATAGTTTTTCTCTTTAAATAAAT
+CACTTTTCAACAAAAAACTATGAGACAATAGTTTGAAATTACAGTATTCT
+TTAAAGGTGCACGCCTGCTCGAATTTCGCAAAAACGTGTCGTGTCGAGAC
+CCCAATTACAGTATTTTTGACCCGAATATCGCGAAATTTCGAGTCTGGGT
+GAAAACATTGAAATTTTTGGCAAAATAAAAGAAATATGTCCTTTTTCAGA
+ATATATTTTCTAAATTTCGAGACGAAACAACAATTTTAAATGAATTTTAA
+TTTTAAATATTAAATATTTCGGAATTTGGCGTTTTTTATGCATGTCGATT
+CACTAACGATTTTGTACTACACGTGGGCAAGTTTATACAGTTTTTGGCTA
+AAATTTGTGAATTTGAACCGTTTTTCGGCGAATATTTGAAAAATTGGCAA
+AACTGGTTCAAAAACAAAAATTTTTTAAACTGTACAAACTGTCCAAAAAT
+TCGTCGTAAATCGACACACCCTTCTCATTTTTTCAAAATTTTAATTGTTT
+TCGAATGTTTTTTTTGCAGAATAATTTGTAAAATGAGCCTTTTGTGAATT
+TTTTTTAATTTCAAAGTTTTTATTATTTTTTCTCAAACCAGCACCTCTGT
+TCTCGTCCAACTATGATCATCATCGTCGAATAACCGTTTCTCGTGATTTG
+TCACATTATCCTTGAGCACAATACATCCACCAGGTTTCAGTCCTTTCTGA
+AAATGAAAATTAATTTTAAAAAAATTGAATTATTTTAAATGAAACAGTTT
+TCAGAGATTTCTCAACTTTTGAGTCCACCACCAGGCCTGCACGTTTTTCG
+GGTTTTATCTTTTAAAAAACTGAAAAATCGAAAAATTTCAATTTCTGTTT
+TGTGGTCAAAATTGTAATTACAGGTAAGCAAATAGTTTAATTTTAAAATT
+GAAAATTAGGGAAATGACCGGACATAAGTTTAAAAACCCGATTTTTTCAA
+TAAAAAGGAAAATTGAAAATTTAATAAAACAGGTTGTAAATCAAGGAGAT
+CGTATTGATTGAAAAAAAATCCGAATGTTCCGGATTTTTCAGTGGTTTTT
+TTTGAAAGAAAATCGAAAAAGTAAATGTTTTTAATTTTTAAATTTAAATT
+TTTAATCGGAAAAAATGTACGAAATTGACTTTTTAATGTGAAAAATTGTT
+GTTTTAAAAAAAAATTTTAACCGATACAGATTTTCTAGACTCAGTTTTTT
+CGGTTGAATATTGTTTTTTACTATTTTTTCATTACAGAAAGAATCCAATT
+TTATTTCGCTTAAAAAATAACCGGAGCATCGAAAATATTTTTTTTTCTGT
+TTTACTCAAAGCATTTCAATTACCTAGAATTTTGTTTAAAAACTACATGC
+TTTATTTATGAACGTAATAAATAAGACCCCCTCTTATTTATAAACTTTCA
+ACATATTTTCAGTTTTCAGTGCTATCTAGTGCTTACCGCACATCTTTTAA
+AGAAATCAACCAAATCCTCATCAACCAAATGCCCTGAAACCCATTGAATC
+CATATCAAATCATAACGTCGTTCGGGCGGTGCAAACGTCTGCAGTCCTTC
+GACGAATTTATCTCCAATTCGTGGATGTTTTCCAATATATTGATCACTTT
+TCGTGATCAACTCCTCGACGACGTCTTCCATATCAACTTTCGAGAAGAAT
+GGCATTAAGAGATGCTTTGTAACACGTCCGATACCCGCTCCGCAGTCCAG
+TGCATAGTCAAAGTAGCCGAATAGATTCTGGAAAATATTTATAAAATTCA
+AAGTTGGCCCAGGGGTGACCGGCAATTTCAAGCAAATCGGCAAATTGTCA
+ATTTTCTGAATTTGCCGAAAATTTGACAAAAACGACAATTTGCCGGTTCG
+CCGAATTTACCTTTTTTAAATTTAATTTTCAATTCAGGCAAACTGACGAT
+TTTCCGTTTGCCGGATATCAATTTGCAGGAATTTCTCAAAGGAATTTTTA
+TTAAGACGGAAACACAGTGCTTTTTTGAATTTTTTTTCCCGTTTTCTTCA
+GATATTTTTATAGAATTTACTGACTTTTCAGAATAGATGTAGGACAATTT
+TGTTGTTTTAAAAATTGAAATTCTGAAATTTCCAACAAAAAAACATGTGC
+AAACCCACAAGTTGGCAAAAATATTTTGCATTTGCCGTTTTTCCCGTTTG
+CCGAAAAGTCTAATTTCGGTAATTGGGCCATTTTTCGAAATTTTGAGCCA
+CATAAAAAACTTTGAACCATTTTTGAGAAGTATTATTACGACATTCGTTT
+ATTTGAGCACAATTTGGGCCTATACTTTCAAAATCGGGGTTTGAAAACCC
+CTATATGTTCGACCGAATGTTAATCTCATAAAAATTTGATGAAAATAAAA
+TTTTCTACGGCTCATAAACGTATAGCCCCCGTCAGTCTCAAAATTTATAC
+GATAGACACTTTTTGGCGTTTATCGCCTATATTCCGTCAAAAACCATTAT
+TCATCATTCTTTCAATGTTGTTTTTTTTAAGGCTAAAAAACTTTCATGCA
+AATTTGTTAGCCGTGTCGTGGTTTATACGAAAATTTCAGAATTTATAAAA
+TAAAGGAAAACGAAAATGTTTCTATATACCCTATTTATGTTCTCTGATTC
+CGAATACCAATGTGAAAAATTCAAAAAAAATTCCCTGATTTTATATAAAT
+TTTTGTAAGCGACAAAAATTGTCGTTTGAATTTCACACTTGGTTACAAAA
+ATTTATGAAAATGAGGAAAATTTGTTTTAATTTTTTCACATTGATATTCG
+GAATCAGGAAAATAAATAGGGTCTATAGAAAAATTCCGAACCTTCACTCC
+TTCTCTGAGTATAATAAATTTAAAATAAATACAGAAAATTTCAGTTCAGA
+CCTCATTAAATTTGGGTATATTTCTAGGATCCGAGTTTTTACACCAGATT
+TACAAACTTTTAGCCTTTCACCGCCTTTTTATGCGCATTTCCCATCAGTC
+AACTCCAAAAAAATCGCAACTTTTGCCTCATATTTCAAGAATATTCCCCT
+TTCTCTCCCCATTGAAAGTCATTTTCGAAACAAGCGGAAGATTCGTCATA
+TGTGGTAATGTGTGGCGTGCGTTGGCAAACAACAAGAAAGAATCATTCTC
+TGAAAACAAAAAGCGTTTTGGGTGCCAAAGTAATATTGAAAATCTGCCGT
+GTTTTCTCATTTTCCATCAAAAGAAAATGAGAAAAAAGTTTCGGCGTTTT
+ATTTGATTTCCGGGAAAGAAGACTCGGAAAAAGATTTAATTGAATTTTTC
+ATAGCAAACCTATATTGCAACAACTTTCTAAAAGGTCAGAAATTGCCGCG
+TAGCCTAGAAAATTGGAAAACTCTTCCAGCTGGTATTATTTCAGACATGG
+TGCATCGAAAATTCGAAAATTACAGAAATTAACATTTTGGAGCATCTGCC
+AGAAAATTGAGATTACAGTACCCCACTTCTGCCGAGAAATTCGAGGTGGA
+AGAGGTCTTACAAAATTTTCGGTCACGTGAAAATGGGAAGCGTTCAGGCT
+CCACACGACGGAATTCACCTAGTTTTCAGGTGAGAAGATATCGTACGAGG
+AGAATTGACCTCCAAATCCTGATCGTGACTACAGGTCGTCGTTCGGAGCT
+GTGGAAGAGTTTTGAAAATCTTCGACCATGAGAGAAATAGACAGGACGAC
+CAAACATTTTCAGTGGAAGAGCTTTTCCTAGGCCATCAGGATGCTATTTC
+GACAGAGCTGAGTTATCCTCAAGTCGTTACGAGGTGTGGAAAAGTTTTCC
+AAAATCCCCGACCAGGTAGAAAATGAGCACACCGATTAAGTTTCTCCAGT
+GGTAGAGTTTTTTCTAGGCCATCATTATGCTATCTAGAAAAAAGCTTCGG
+CCATGGGGTTTTTAGGCCGTCTATTTATTTCTCATAACTTTCTCAGAAAT
+TCGTCTATTTCTCAGAACCCCCCAATGATAAGTTTTTTGCAAAAAAAGTT
+CTGCTTTGCTCATCAGCCGTAATCAGGTGACCTCATTAGGCCTACCCAAA
+CACAGATTTGTCATTATTTTTCAGACAAAAAACACGAAAAAAATCTTCAC
+GCATGGGGTGATAACCTGATTTTAAATCTTACTGTGCCGGCTGGCGCGGC
+GAGCTTCGATCACTGAGCCGAAAGATTATGAAAACTATGGGAATGACGGC
+GTAGCCTAGAAATCGTCCAGGCAGAGATTCTGTCTAATTTTCGAGCATAT
+ATCTCCCAGTTTTGTTATTAATTTAAGTAAACTCAAACCTAGAAACAAGT
+AAAACGGGAGGGGGGGGGGGAATATCAGAAAATTAAATCTTGCGACACTT
+TTCCATTGATACTTTCAAGGTAATGCCCAGAGGTGTGCGGCAAATTTTGA
+AACTTGCGCATGCCGCCTTTTTTTTTTTCTAGAAAACAGTCAGAATTTTT
+TGTCGAATTTGTTGAAAATTCGCTAATATACTGTGAGTTTAGAAAAAATA
+ACGAAAAAACTCGGAAAAGGAGGAAGAGATCTGAAATATGTAGATTTTTT
+TAGAAAAGACCAGAAATTACTGAAAAATTGGCATTTTTCGTCGAAACCCC
+AATATACTAAATTATTCGGATTTTTAGAAAATTTTCAAATTCACCATACA
+GTGCATTTTTTCCTACTTCTACGACTTTAAAGGGGGGAGCATTTATGCGG
+AAGGGTCTTGCCGCGCATTTAGTCATCATTTTTAGCAGTTTCTGTGTAAA
+ATTCGCGTAGATCACATGAAGATCACAAAATATTTATCCCATATTTCGTA
+TTTCTGTTGCTTTTTCACAAATTAATTGTGATCTACGCGTGATCTCCGCG
+AATTTTGAGCAGACTTTGTTAAAAATGATGACTATGTGCACGGCAAGACC
+CTTCCGCATAAATGCGCCCCCCTTTAAAGTCGTAGAAGTGGAAAAAAAAT
+GCACTGTAGCAAAAAATCGAACATTTCTGTTCGATTTTTGAATTTCTCGA
+AATTTTTTAAAATAATTTTTAAAATAACATTTTTATTTTATTTCGAAAAC
+TACCGATTTTAGAAAAATTCTAAAATTTCGATTTTTTTTGTTGATTTTTC
+GATTTTTAAAATAAAATTTCATAATTTTTTAAACCGATCTTTCTTGCTTT
+TCCTGAAAAATCGATGATTTCTATACCTTTTTCTTCAGTCCTTCAATAAA
+TCGTTTCGACGCCGATATGTCGGGCGCGTGAAGCGCTTCGAATCCGCCGA
+GCATTCCGTTGACGTCCTGGCTCGCGCGGCTCCAGTATTCCTCCGCCTGA
+AAGAGAATAGTTGAAAACATTGTTTTGAGACTTAAAAATTTTTTTTTTAG
+TTTTTTTCAAAAATTCTTACATGTTATAGAGTTTTTTTTTCAAATTTTCA
+GCTTTTTTCAGAAAAACTTAGTATTTTCGATAATTTTAAATAAAAAAGTT
+TTTTTTCAAAAAATGTTTCGGTTTTTTTTTTAATTTTTGGTCTAAAATTC
+TCCGCAAAAGATTTGCGTGCTGGCCGAACTTTTTGATTTTGTACCTTTTC
+ATAAACATCTTCACCATTGTGAATTCTAGAAGATGATGAAGAGCTCATTT
+TTGATGTTGTGACAGCTGCTCCGAGCAATCTGGAGACTTTTGTGACGAAA
+AGACGAGAGGTCACGGATATGATGATGATACTGGAAATGAGATATTTATA
+TTTACTAGTTCATCGGGAAAATTATTACGAGAAAGATAAACAGACATGTG
+CGTTTTTTTAATGGAAGAGAAACACAAGAAAAATCTGGAAAACTAGGCCA
+CGGCTATCAGTGTCGATTTACGGCATACGGTCTCGACACGACTATTTTTG
+TTAAATGTGAAGGTATGCACCTTTAAAGAGTACTGTAGTTTGTAACTCTC
+ATTGCTGCAACATATTTGACGCTCAGCGAAAACTACAGCAATTCTTCAAA
+AGACTACTGTAGCCTTTGTGTTGACTTACGGGCTCGATTCTCGAAACGAA
+TTTCTGCTCGAATTGTGACAGCCATATTCAATTTGGTATAGTCTTTTCGT
+ATTTTTTGCCATTTTTCTGTTTTCTTCTAATATTTAATCTATTATTAAAT
+TATGTCCGTAACTCCCTCCAAAATTAGAACTGCGACCGAACAGAGATTCG
+TTCCGCCCCATATTCCGGCCAATCAGATCGAGTAGGCGGAGTTCGAAGTC
+GCTGATTGGTTTGAAAAGTCGCGGAAATTTGCAAGTTTTAAGGTAGCGAA
+AACTGATGACTATTGTAGCGCGCTTGTGTCGATTTACGGAATCTCGATTT
+TCAGGAATGAATTTTTAATTACATTTTTTCGCTCAATTAATATTCTAAAT
+AAATAAATAAATGATTTGAATTAATTTAATTTCATTCGAGCCCGTAGATC
+GACACATGTGCTACAGTAATCATTAGTTTTCGCTACGAGATATTTTGCGC
+GTAAAATATTTTCCCGTAATAACTCTACTCCGACAAACATTACGACCTCC
+ATGGAGGCCTCCAGGTATAGGTGAGACTCTTGTATTTCCAATTCAGAGAC
+AATGCGTCACTGGAAGAGAAAACGAAGCGGAAAAAAAAACACGGAAACCC
+AAAAATAGTGTTTGCCCCGCTCTATTCTTCTCCAATAATTTCTGTGTCTA
+ATTTTGAAAGACTCCACCTGTGTATGCCTTCTCGACATAAACCCCCCCCC
+CCCCCCCTATCTTACATGGTACTGATAACACTTTCAGTCTTTCACACTTT
+TGGCGCGCAACGCCGCTCTTTTTTCGCGGCGAGCTGATGACGTCATCAAT
+TTTTCATCGCTTTTGATTATCTTCAATGTTCTAGAAGGGCACATAGGTCA
+TCCTTATTTTTTCCTTCTCTTTCTCGTGACGGCCCTTGTTGCGCATGCCC
+GCCCCCTAGAGCAGGGCGTGGCCTGAACGGCGGCTCCGAGAGCTACTCAT
+TCTTGCCGCGTCACCCTCCAGCGCCACCCAAACTTCTTCGGTTCTAGAGA
+TCGAGAAGAACGTATGATTTTTTAAAATTATAATTGTTTCTTTCGAAAAA
+AAAAATTTCATTTACAGTAAGCCAAACATACACAATCAACATGAAACTCG
+TAATTCTGCTATCTTTTGTTGCGACAGTTGCGGTTTTTGGTGAGTTTATG
+CTTTAGATAATACTTTTCCGCCAAAAATACAGTTGCCGGTCTCGGTATGG
+CAATATTTTTGTTAAATTCGAAAAGCAGTGAGTAATGTAGTTTCGAATTT
+TCGTTTCTGCTTAATTTTCATCAATTCATCGTTTTTCTCACGACTTCTTC
+TTTATGAAAAATCAATGAAAATTCTGACTAGGTCAGCTTAGGGGTGAGGT
+ACCTAGAGACGCCACATATGCCAAACGGAAGCTGAGATCATTGGCTACAA
+GAATATGCTTTCAAATTCTGCAACGGACCTCTGGGAGTCTGGAAATTCTT
+GTCTGAAATTATGCTTTTGAATGCTCGAAAGTGGTAAGAATTTAGAATTT
+ATTACAGAAAAACGTTTAATTAATAAAATTAGTTTTATACTTGAAACAAG
+TACTGTATGCACTGTATCAAAACACATTTTCATCTTTTCTAGGTATTCAA
+CTTCACGTTTTTCTGTAATAAATTCTAAATTCTTACCACTTTCGAGCATT
+CAAAAGCATAATTTCAGACAAGAATTTCCAGACTCCCAGAGGTCCGTTGC
+AGAATTTGAAAGCATATTCTTGTAGCCAATGATCTCAGCTTCCGTTTGGC
+ATATGTGGCGTCTCTAGGTACCTCACCCCTAAGCTGACCATTCCCTAGTG
+AGCAAACAAAATTTTGAAATTACAGTACTATTTAAAGGCACATTGATTTT
+TTGGGTCAAGCAAAAATTTGTCGTGTCGAGACCGGCTACGGTATTTTCGC
+GAAAAATCGCAAAATCTTGCGGCTGGGATATACTTGTGCGAAATACTTTT
+TGCATTAATTTTGAGCAAAATTATTTTTTTTAGACTTTTTGAAATCCAAA
+TTTTTTGGATTGCGAAAAAAACCTGTGTCCGGTTGTTTCATTAGGCCAAC
+AAAGTTCCTGGAACACTGATGAAAACCATGATAGAGGCGGAGCATAATAT
+CGATTTTTCGTACTTTCCTGTATTTCTTCTTCTATATGGCCGAGTAGAAC
+AGGATTAGGGGTAAAGTCAAAATTTTTCTCATATGGATATCATATGGATA
+TCAAAATTTTTCTCATATGGATATGGAGAAAATTTTTCTCATATGGACTT
+TGAAAGTTGAATCACTTGACATCTGGGAAATTAGTATTCCAGGCGTAAGT
+CGGATCTGTTAGAAACGGAATACTTATAGGCTTCGTGAATTAGGTAGACT
+TTCAATTAATCTGATCCATGGGAGTCAGACGCGGTTTCCAGGCCTGACGC
+CTGCCTCCAACTTGCCCGCCTCACGCCGGTCTCTCGCCTCATTTCTGCAC
+TGTGACGAGACAGACGAAGGTCGCCTTCTGGCGCCCGCATGGAAATCCTA
+CGAATATGTCAGCTTCTGATGGGACTCCGTAAATCGACACACAGGGGTAC
+CTCAGACATTTCCCTCCCCCTTACAAATTGTTAGGACAAGGAGGGGGAAT
+TCATCTCCACTCGAGACACACATATGTTGTCGTCAGTGAAGTGTAAAGAT
+CTAAACGATTGCGTGTATGAAAAAGCACTCTATGATCACCTTTTTCATCT
+TCCTACACCCTTTTTAGGTGTGGTGCCCATCGAGCACTCACGCCAGGCAG
+GGAGAGCACCGGTCCCTGACTAATGGGATTCGAATGTTTTAGACCGGAAA
+TAGGAGCGATGAAAGAGCATAGAAATGATCATTTGGAAATCACGTTTAAT
+TAGGTTACGGCGAAAATTTGCAAAAAAGAGCAGGAAACTTGGCTCAAATC
+CTTCGAAATATAACAACTAGGACTTCCATGTAGGCGTTAAAGCGCCCTGT
+CTCTCACCCCAATCCGTACCTTAAGCTGAAACAAACGTGAACTTTTTTCA
+TTTCTTAAAGGAGTATCGTCAATGGGAAAATTGTTTTAAAATGTAGTATT
+TGTACTTCAACTTCCAATTATTGCAAAAGAAAAACGGAAAAAATCCGTTA
+ACATTCAGCATTTTAAGTCGAAGAAATCTTTAAAATTTAACTAGAGAAAT
+CCTAGGCCACGACGCTCATTCGAATTTTAATTTGTTTTGATATTGTATTT
+TGAAAAAAAAACTTAATACAATTCCTTCTTCCCAGTTTTCTATAACTTTT
+TGAGAAAAAAACGAATTAAATTCCGAAAAAACTACATTTAAATCAATATT
+TTGTTTACGAATATGGCCTAGAAATCGCGTGGTGGCCTAGGATTCATTTG
+CGCGCGAAATTCAAATTCCGTCACTTTCGTCGATTTCAACGGCTAAATGC
+TGAATGTCAACGGATTTTTCCCGTTTTTCTTTTGCAATAATTAGAAGTTT
+GAGTACAAATACTACATTTTAAAACAATTTTATTTTTGGTATTTTGACGA
+AAAATTGATTTATTGGTTTTTTTGGTTGTTTGGGACCAAAAAATCCAAAA
+AAAATGTTTGGCGTGTCTAGTTTCGACTCGAGACTATTCTGTATTAAAAA
+TACATTAAAACATGTATTTTAACACAGTTGTGACGTCATAAATGTATTTT
+GATACATTTTGCAACATTACTTAAATAACCCCATTAAAAATTAACCTAAG
+CATCAAAAATTTTTTGGTTTTTTTGGTTTTTCGAAAATTTCAATTTTTTT
+TGTTTTTTGGTTTTTTTTGGTTTTTCAAAAACTTCAATTTTTTGTTTTTT
+GGTCCAACATTTTTTTTTGGTCTCAGCTCTGCTGCCTACCCTAGAAGAAC
+TAATAGCGCTTCAAAAACTGATGAAAACGTTCAAATTTGTCGAAATATTA
+CGAAAATTTGAAAAGTTGGCTCAAATCTAGATTGAATCGGCCGATTTTCC
+ACAAGTTTCCAAGTTTCCACAAGTCGCCACATATCCCGAGAAAAATCGAT
+TCAAATTGTTTGAAAATTGGAATACTGCGAATTTTGAACCAAATTTCCCT
+GGCTTCTCTGTTGAAATACTTGAAAATACCGCGAAGCAAACAAAAAATCT
+AATTATTACGTGAACACAAAATTCTGAAAATGCGTATATATTGCGCAACA
+TATTTGACGCGCAAAATATCTCGTAGCGAAAACTACATTAATTCTTTAAA
+TGACACGCTGTATGTGGTGATTTACGGGCTCAAAAAATTATTTTCGAAAA
+TCAAGCCCGTAAATCCACACGTAGTAATTATATAAAGAATTACTGTAGTT
+TTCGCTACGAGATATTTTGCGCGCCAAGTATGTTGCGCAATACGCAACCC
+CATATGTTGATATATACTGATGTGAGGATAAAAAACAACACAACTTTCAG
+CGGCTCCATCGGCTCCGGCAGGTCTCGAGGAGAAGCTGCGTGCTCTTCAG
+GAGCAACTGTACAGTCTGGAGAAAGAGAACGGAGTTGATGTGAAGCAAAA
+GGAGCAACCAGCAGCAGCCGACACATTCCTTGGATTTGTTCCACAGAAGA
+GAATGGTCGCGTGGCAGCCGATGAAGCGGTCGATGATCAATGAGGATTCT
+AGAGCTCCATGTAAGTTAGTGGTGGTGGCCGGAAAAGAGAAAACTCGGCC
+AAGCTGCTCGGAGTTTTTGAATTTTTGATAATCCGAAATAAAAATTGATT
+GCTCGAAAAGGAACAATCTTTTGGAAAAAAACGAATTTTGTCATTTTTTT
+CAGCAAAAATTGATTTTCGAATTTTTCCAATAAAAAATCGATAATTTCTC
+CCCGTGCAGTGGAAAACAAACAATATTTTTTTGTTGATCGTTCTCTTCCA
+AACCCGGAATAGGTACACACATTCCTGCGTCATCCCATTCTCTTATCACA
+CTTTTTTTTCGAAAATAAAAGTGTAGAGACGGAAAAGTGAGAAAGGAGTC
+AATTTTATGCGAAATTTTGCATGATAATACACTCAAATTAAAAAAACTGC
+GTGGCGTGCACTGCAGAAAACCTCATATTTAGGCCCCGCCTTTTTCTCGT
+CCACTCACGGAGAAAAGGCAAAAATTTGGGGACCAACCAATATCAGGCCG
+CCGACATCCTACGGGTTCCGCGCGCCGCTATGTTTAACTCGCTGTGGGTG
+TGGCGAGCTGTCTCCGCCCGCTGCGAGTTAAACATAGCGGCGCGCGGAAC
+CCGTAGGAAGTCGGCGGCCTGATATTGTTGGTCCCCAAATTTTTTCCTTT
+TCTCCGTGAGTGGACGAGAAAAAGGCGGGGCCTAATTATGAGGTTTTCTG
+CAGTACACGCCACGCAGTTTTTTTATTTTGAGTGTATAGGTCTCGATTCT
+CGAAAGTATGACAGTTATTTAAATGATGAACTCGTGATGACTGTTAAATT
+TTTGGAAATTTCGGGGGAATTATATCGATTTTTCGATAAATTTACAGGAA
+AAAAGTCCAAAATCTAGGTATTCCATGGTAGGCAGGCGCGATTTCTTGAC
+GCCTGCCTGGAATCTGTCCGCCTCACACCAAAAAATGTCAATCATTTTGC
+TGAAAACCAAATTAAGAAATGAAAAAGTGCACTTAGAGATGATGACGGAG
+GTCGCCTTAAGGTCAGACAGGTTAAAAAACCGATTTTAGTTGAGTTTTCC
+CGAAATTTTCTGAACAACCGAATTAGAAATATGCTGCTTGTCATTTTTGA
+GTAAAAATTAACGAAAACTTCGACCAAAACCACGAAAAAAATGAAGAAAA
+TAAAGATTTTTCGAGAAAATAACAACAAAATCCAGCAAATAGTGAAAAAT
+AGTTTTATCCGAGAAAAAGTAGTTTAGACGCTATGAACTCTCGAAAATCA
+GATTTTTTCAATCTAAAAGCCATAAAATTATCGATTTTTTAAAAATTCTC
+ACTGAAAACCGGCGAATTTCAGTGCTCCACGCAATCGAAGCCCGCTTGGC
+CGAAGTGTTGAGAGCCGGAGAACGCCTCGGAGTCAACCCGGAGGAAGTTT
+TGGCGGATCTTCGTGCTCGTAATCAATTCCAATAAATATTCTTTGCCCTA
+AATACTTTAAATTATCCATCTGACAACTAAAATTTCGGTTCTTCTTGGCT
+TCTTCTATTTGTGAAATGGTTTATTTTCCCCCGAACTCTCAAAAGGTTTA
+AATATTGTTCGATTACCCCTTTTTATCAATTATTTTCTTCAATTTCTTAT
+TTATCATTATTTTTCTAAACGAAGACGGATGTGATTTTAAATTATGTTAA
+TGGACTATTTTACAAACTGAATAAATTCAGCATGTTGGCAGGTTTTTTCA
+GTAGTTTTTGAGTGAAAATAGAGGTAAAAAGACAGAAAATCAATAAAAAA
+TGAAAACAAAACTATGAAAAATGGTTGAAAATCGAGCAAAAATCGTTCAA
+AAAAAAATAAATTCAAAAAATAATTGCGTCGAGAAACGCGTCAGTAGCCG
+CTCTCTGCGTCTCTCACCCTTCAGCACGCGGAGAGAGCCACGAGAAATGC
+GCAAAGGCTAAATTCGGCGCGGAAAATCATTTTTCAAAATAAATTCGACG
+AGAAAATCAATACTTAAGTAATTATCGATTTTCAGCTCGTTCAAAAAATT
+TTCAGAAACGTTTTAGTCGTTTAAAGGTTTTTTTAAAATTAAAATCGTCG
+GAAGTAAAAAAATAGCGCGGATGGAAATCTACGGAGTGCGGAGCGAACAA
+ACGCGCGGTAATTCAAATGGGTAGAATAGTCAAAATTGAAAATTAGCCAG
+CATCGACCGATTTTTTTAAAACTTAATGGATTTTTTCGTTTTTCTTTTGT
+GGTATTTCGGCATTTAGGATTAGATAGCACATTTTAAAGTAAAATTCCCA
+TCCAAGCTACTCCACCTTCTCCAGACTGTACAGTTAAACCAATTTGAAAA
+GTGTATTGTATCCCGTTTTTTTTTCTGAACAATTTTGAAAATTTTTCGTT
+TATCCAGGATACGATAATCATGATTCAAATTCGTTAACAAAAAATGAATA
+TATGAGAGCGATTAAAGCATTTGTGTCGGAAAATATGGGTTAAATGGGGA
+GAAGGGGGCGGACATTTGGATGGGGTACAAAAAAATATGCAAAAAATGGG
+CTAAAAACAATATTTTCAAATTATGCCCGACAAAGGTTCAAAAGTCAATA
+TATAGAAATGAGAACATGAGTATTATGCCACGTGGCGGGAAAAATATGTG
+GAATGTAATACGATGAGATCCTTGTGAATACAAAGCTTGTGACGACGTGG
+CCGAGAAGAACTTTTTAAGCCAACGAGAAAAAAGGGGTTCAAGGCCGAAA
+TTTTTTTTGGGCCACCTATTAAGTTAAATTGAAAATTTAAAAAAAACACA
+GCGGATCCAATTATTTGCCGAGTTTTGACTTGAGCTCGGCGCGATACGTG
+TCGATTGACTGAAAATATTGTTTTTTTTTATTTCCGAATAAAAAATGGTG
+AGTACCTCCAAAATTAGCTTTTCATTGTCCATATAGAACTTTTTGATTTG
+TTCCACAGTTTTTGTGGCCATCAACTCGGCGATCAACTCGAAATTGTCCT
+TGTACCAGTGGAAACCTGAAGGAATTTCGGATGTTTTTGCTTAATCATAA
+TCATAATAATCTTAATCATAAGACTTGGAAAATGCGAAATTTTTCGAGAA
+TATTCAATTTATCTTCAGATTTTATTGCAACAAATCGATTTTCAACATAA
+AATTAATTTTTCCAACTTTTTTTCCCAATTTATGAGAGTTTAAAGATTGT
+TTTAAAGCAAACCGCCAACTTTACATAAAAAATTAAAATATTGTGAAAAA
+AATGATGAAATTTAGCAGATTTTCTGATAAAAAATTGAATTTTTTTGGAT
+TCGCGCTTCAATTTCACATTGTTCTTTTAGAAAAGTCGAAATTTTATATT
+TCCAATTTTCAGATTTAAAAAAATTTAAAAAGGAATGAACTTTTCCAAAG
+AAAAACTGAATATAACCAGAAATTGTGATTTTTCAGCATTTTTTTTTAGG
+TTTGAATTTTTTTTTCATGATTAATCACGTGAAAAGTCAATTTTACCGCA
+AAACATTTAAAAAATCAAGATTTTTCAATTTTCTCTGAATTCCTGCAGAT
+TTTTCGATGAAAAATTGAATTTTCCTTGGAATTTATATTTTTCGGGTATT
+TAAAGTTTCGGATATTAAAAAAAATTTTCAATTTTCTCTGAAGTTATCGA
+TAAAAATTATTTTCTGCAAAAAATCTACTTTTTTTCGTTGAATATTCCGG
+AAAAAAAATCAGAATTTCAAGGCACATTTCCTTTTCTAATCTAATTCGAA
+TAATTCAATATTCTTTTAAAAATTCGGGGTAGAAAAGGAATTGTACCAAT
+TTTTATTTTTAAAAGTTAATTTTTCTAATTTTCAAAATTTTCTTGAATTT
+TCGAATTACAGATTTTCAAAAAAATTTTTTTTGTTTTTTTTTCTCGAAAA
+TTTGAAATCCATACATCTAATAGCATTCTTCTTTTCCTCAGGACTCCAAC
+CATAATTTATCCTGACTTTTCCAGATCGATTGCCATTTGTTGCAGTAGTA
+TCTAGTTCAGGAGTAAATCTCTCGAATCTTCCCTTCAACGCCATCATATC
+TTTCTTCCAATTTGCAATTTCTCCTTTTGGTACACGGCTGTATGTCATTG
+TTGCACGGAACATTTGTTGACGGGCTTCTTCATTCAGAATTCTGGAAAAA
+TTGATGTTGTGCGATTTTTTTTGGTTAAAAAAAACAATTTTCGTAAGTTT
+AATTAACTAATATTTTAAAAAATCTCTCATTTTCTGAGGCACCACGGATT
+CAAGATCTGGTGGGATTCCGGATCTGGCACCGTGCCAACGCATTAAATGC
+AATTTTTCTGAAAAAAGGGCAACGAAGATCCGATTTAAAAAAATTTTTCA
+ATTATTTTTCAAAATTTTCACTAACTATAAGAAATTAGAGATTTTTCACA
+AAAATTCCAGTTTTCTGTTAGAATTTGAAAAAAAAATTGAATTTTTCCTA
+AAAAATTTGTAATTTTCCGATATTTCAAGCTGTCAAAACCTAAAATCTGA
+AAACTGAATTTTTAAAGGAAAAATTTTGAGCATTCTTATCAAAAAATTGT
+TTCAACTTTTTCTCAAAATGTTTCAACCTTTTTCTTTCTAAATTCTGAAA
+AGCATATCTCAGCTTTTGCTAAACTATTTTTTTCCTCAATTTTTGAGAAA
+ATTAAAATATAATATATAATATAGTAAATATTGCTTATTTTCTAATAATT
+TTTGGTATTTCTATTCTTTCGTTTTTTTTTTCAAAAATTCCAAATAGTTT
+TAAATGTTCATATTATTTTTTTTGACGAAAATAAATTTTAATTTTAAACC
+GGAAAATTGTTTCGTAACTTTTTTTTTCAAAAAATTTGAATTTTCGACAT
+GAAAGATGTAAAGTGTAATTTAAAAATAATAGTGCAGGTATTTTCAGTTT
+ACAGCAAAAGTCAGTTTAAAAAATTTCGACTGGTTTTCAAAATGAGTTTC
+CTTATTTTTTACACGTAGAACTTTTTTTATTTTCCGATTTTTTTTGTTGC
+GCAGAAATTTTTTTTCCGCAAAATCAGGAAAAATTCAGAAAAAGACAGTC
+AAAAAATTGTAGATACAATTTTTTGACTGTCTTTTTCTGAATTTTTCCTG
+ATTTTGCGGAAAAAAAAATTTATTTTTTCATGAATAAAAATCGAATACCC
+ATCCAATTCCACAAACTTACTCGTTCTCCTCCATACATTTCGTTTGTTTA
+ACTCTCCAAACAAGTGGAACACACATATGATGTTTTCTCTTGATATTATC
+AATTAATGCCAGTGCAGCCGGTGTATCGAAGCACCGTGTCATTCTGCACG
+TATTCTCATCGATTGGATCAGCTTCAATCGATTGCTCCACAATGTAGGGG
+CCTGATGGTTTACGGAGAAGGCAGTCGTCTGGAGAAAAATAGAATAGAAT
+AATGATTTTTAGGTTATTTTACGTTTAAAAATCTAATTTTTAAGACGCGT
+AAACGTTGAGCTCATTTATAAAAATTCGGCAAACCGGCAATTTGCCGAAA
+AATTTCGGAAAATTGTCGGTTTGCACATTTTTTCTTGAAATTTCAGAACT
+TCGATTTCAAACGGCAAAATTGTATACATCCTATCAAAACATCAATCTTG
+AAAAGCCAGTAAACTCTATGAAAATGTCTAAAGAAAAGAAAACGGTAAAA
+AAATACAGTTTTAAATGTTTCCGTCTTATTAATAACAAAATTCGACAATT
+TGCCGGAATTGAAATTTTTTTTTCTCCAATTTCCGAAAAAAACCCACCGA
+CCACCATAATATCATCGTCTTCTTCTTTTTCTTTTCCAATTCCAAGCCGT
+TTGATCGCTTTTCCGTTGGCTGGCTCCATGAGCTCAAGATATCCGTATAC
+ATAAATTTTCATGTCTGAAAGAAAATTCAAATTTCTTCTGGAATCAGTTA
+TTCGAAACTAACATTCTGGACATAAAACTCGTTGCCGTCGTTTTGTCAGT
+GCACGGAGGCTTGCCGGACGTGGAACACGCATCAAACGGAAATAAAGGAT
+ACACGGTTTACATTCGTGACGCGACATTACACGATTTAGCTTAAAATTGT
+GAAATTAATTTTTTTTAATAGCTCTTTATTTTTTTGAAAATTTCTCCCAT
+GCTTTTTCCATTTTTTCAACGAGTTTCCTTATTTTTTGTCCATTTACTGT
+AAGTTTTTTTTGAGAATTTTTTTTTGTTAATTTAACATTTTATTAGCTCA
+AAACATTTATTAGCAAAAATTTTATTAGCAAAAAAATTTTTTAATTTTTT
+TAAATTAGCTCAAAATTCTCGAAATTTTAAATTTTTAGGGTAAACAATAT
+AAAACTTAGGGAGTTTTGAGCTATAAAATGATAAATTGATTTTAAAAAGG
+ATGAAAAACTTATTTTAAAAAACCGACAAAAATCGACAAAAATGAAGGGA
+ACAGGCAGCAGCTTAGCCCCATGCTTAGCCAGCAGCCCCGTAGCAACCCA
+GTATCAATAATATCCCGTGCCAATTTTCATAAAACTGAATATAAATTGGG
+TTGATGTTGCTAAAGGGCTGCGAAAAACTGACCTGGGATGAAGCTGGGCT
+GCAAGGGGCTGCGAAGTGCTGCGAGGGCAAAGCGCTACAGTGCTAAAAGG
+GGGCTGAGCCCAGACCCTCAGGAAAAAACTCATACTCGCAGCCCTTCGCA
+GCCCACATTTGCGCTCTGATCGCGTGCTATCCGCGCGCACAGAATTTCGA
+AAGTATTTTCCAAATTCGGAATGCGCGCGGAGCAGACGCAATTAGAGCGC
+GGATCTGGCACGTAAGGAAGAAGTGTGACTGGAGCACGAACCAGTAATCT
+AGTCGCGCCCCGTCCGCGCTCCAGGAGGAGCGATTTGCCGAGCAGTTCAG
+CCCTTCGCAGCCCTTTAGCAACAACCAAATTTATACAGTTTTATGAAAAT
+TGGAACGGGATATTATTGATACGCCTAAGCAGCCCTATTAAATAGTGATG
+AGGGCGTAAATGAAATTCGCCATTTCCAGCTAAAATATAAATTTTTTGAA
+TTTTTTAACATTGATATTCGGAATGGATTCAGCAGAAAATTTGAAGTCAT
+TTGAAAATATTTTCCAGATTTCGGTACTCCACTTTTAAAATTGAATAAAA
+CTGTAGTCTTTATTCAATGTTTCTTCAAAATTTAAAAAGTAGAATATAAC
+TGTGAGAAAATTTCCAAAATTGTCAAAATTTCAAATAGCTGAAATATTTC
+ACGGCCCGGCGGGGGGTACATGGATGAGAATTCTCTACCGTATTCCAATT
+TGGCTGACTGCGTGCTCAACGTTGAATACTCAGTGTAAACTTTCGTACAC
+CGTTGCGTACTGCACAGCGCGCATTTTAATTGACGACATTTAGCAAAAAT
+TGAACATAAGATTTTTCGGAATTATGAAGCTCAATTTTCACAAAAATAAT
+GAGTTTTTTGTAGAATTTATGAAAAAACGTGAATATATAGATTTTTTGTT
+CATGATATTCAAGAAAAAGCGATTTTTAGTTCTTCACAGAGGAATCCTCT
+CGCATTTCACTTGCTCATGATGTTTTTTGCTCCACTTTAGGACGATAAAA
+ATGCGAATTGTTGATAAAATGAATGAATAATATAAAAAGTGCAAATATGA
+CTTCAGCAAGTGTTAAATCCCAAATTTTTCCTGCGATTTTCTGCTAGATT
+CCTGGTTTTGAGTAAACAGTCTGATATATTCATGATTATAATGATAACAA
+TAACGAACATAATAATAAAAATGGAGAGCACAGAGAAACAACAAATTGCA
+AAAACAGCAACTGATATCAGAATTAACGACGACCACGGAAACCGCCTCGG
+TCTCCACCTCGCCCACCACGGAAGCCACCACCTCTGTCGCGTCCTCTGAA
+TCCTCCTCGATCTCCACCGAATCCACCTCTAAATCCTCCATCGCGGTCTT
+CTGATCTACCACGGAAGCCTCCACCTCCACCAGGATCTGTTGAAAGTCCT
+CTGAAGCCTCCTCGATCGCCACCTCCACGGAAGCCACCACGATCCGCGGA
+TTTTCCTCTATAGCCTTCGAGGCTTCAGTTGTACCCCATTCTTCGTTGGC
+ACGCTTCAGATCTCTACAAAAAAAACAAATTAGAAGCATTCAATTATCGA
+AATGTGTACCTATCCCGATTTATCGCAATCTGTCTATTCTTCTCCTTCTG
+ATTCTCAACTTCTTTAACTTGTCCAGTAGCGGCAGCTTGCTTACGAGCAG
+CATTTTCCCGAATCGCCTTCACCTCTGCCTCCTCAGCATCCTGTTGCTCC
+TTGACAATCGTAAGTCTTCGAATGACACGTTGCTCACTCTCCTGCTCACG
+ACGCTTTTTCATCTGCTTCTTCTTGTTTATAGTCACCGCATTATGCTTGT
+GATAGAGAACCTCTCCCTCATCGATTTCTTCTTCAATTTTGACGAGTTCC
+AGGGTCAGTCGGGTCCGATCTCACGAAGACGGACGTTGCTATTCTGGCCA
+ATTCCGCAGTCACGTCCTTCATAAATGTCTTGTGGAAGTTCTTCTTGCTG
+AGGGGGCTGCTGAAACCAATGTCGGCATGATGAGAGTTCCGGTCTTCTGA
+ATCCATTTCCTGCGTGGGCTGTGGCGACGAGCTGCACGTCTGAAAATCAA
+GTTTTTGTAATTTTTGGGCGCATGATATGGAGCTGAATCATTCGATTTTA
+GAATCAGCATGCTTTTATTCATATTTTAGGATCTTTTTAAAAAATCTGGA
+CCAACAGTTTTCGAAAAAATTTAATTTTTGTTCAGAAATGTGAATATTCA
+CTAAATCGAAAAAAATAATTGCAAAATCCGTCAGCTGAACATTCAAAACT
+TATCAATTTGAAATCAGCATATTTCAGTGTATAATTAAAAAAGTTTCAAA
+AATTCTGAGACCAATTTTTATTGAGAAAAATAATTTTTCGCTCGAATTAT
+TGAATTTTCACTAAATGCAAAAAACAGTAAACTTGGGCCCATGCTACAAG
+CCTGAATCTTTCAAATTAAGAACCAGCATGATTTTTTCAATATTCTAGGA
+CGTTTAAAAAAAATCTGGACCAACAGTTTTTGAGGAACGTAATTTTTTAT
+ACAAAAATGTTCTGATTTTTCACTAAACTCAAAAAAATAGTCAAGTTGGG
+CCCATGCTGTACACCTAAATCATTAAAATTCAGAACCGCCATGTATTTTT
+TCTTACCAAAGGCTCTTTAAAAAAAATCTGGACCAACAGTTTTTGAGATA
+TTTAGAAAAACAACTCACTTTTCGACGTTTTTCGCCTTTTCGTGGCTCAC
+CCGGTTGATTTTTGCGGCGATTTGTGGTCTTTCGCTGAAAATATTATTTT
+TATTTCAATTATTAACGAAGAAAACAAGAAAAAACGACGAGAAAACATCA
+AAAAAACGCGAAAAAACATCGAAAAACCACCGCAACCTCATGAACAAAAA
+AAAAGCATTGCAGCCGCGGGACTAGTTTTCGCAACTTTCTAGGCCATGTC
+CCGTTCGCCGTGCCGTGTATTTGTTTAATTCCCTTTTTGGAAAAAGTCAA
+CATATTTTTCTAACAAATCGTTTTTCTATTAATTTTTTTCTAAAACTCAC
+AATCAACAGATCACTTTTTGCATTGCAATTCTCACAATATCCCGACGGAA
+CCCTCTCCAAATGATTGACCTCTTTGAATAGTTCATCATAAGTGTCGGTT
+TCATTCAAATGCACATTAATCATTGTTTTATAGTTTTGCACTTTTTTCGT
+GTTGTAATAGTATTGGATAATGGAAGAAAGCGAGCGTTGGGGCATCTGCA
+AAAAATAATGAAATTTATTTTCTTTTTATGATTAAATTAAATTTTCAAAA
+ATTCCCTTTTTTTGACATATGCACTTACAGCCGCATGAATCTTCTTGAAC
+CGTTTTCCGAAATGAAAGAAGCAAGTGGAGAAAAGACTAATTTCTTCTGC
+CGTCCAATCATCATGAATTTCTTTTCTTCTCATCGCTTGAACCATCGCAG
+CGTCGAAATCATTTGACTGTTTGTTCAGAATGAACAGAGCCTGTAAAAGC
+AGTTAGTTTTTTTTTCAAATTCAAAGTACATTTCCGAAAAATAAAAAAAA
+GGCTTGATTTTTTAAAATCTCGAATTTTTATTATGGTCAATTGTTATTTT
+TTCCAGAGAAAAACTCATTTTCTCCCAATTTTCAGACGTTTCTCTCTAAA
+TTTGGTGTTTTTCCAATCGTACCCTATCTATAGGTAATTGATATCGTCCA
+GTAGCTTCTGAAATGTATTCTGTAAGCCGATTCTCGTTCATTTCGTCTGG
+AAACGCCCAAATTTGTTGATCTCTGCACGGTTCTTTTTCCAATTGCTCTG
+CAGTTGGCTGTATAATCGCCTGATATTCGGTTCCCACGTGGATTAGATTG
+TCGACGTTGGAAAGTGGATTTGCTGGAAGAAATTGGGAATTTTTCAAGGT
+TTTAAGTGGATTTTCAAGCTATTTATAAAAGCATGAAAAAGCTCAGAAAT
+GACTATAAAACCTTTTTTTACGTCGTATTTTTTTCAATGAAATTACCTAC
+TTTTAATTAATTGTTCGGCTTAAAACCAGAAAATTGTTTCATATCGATTT
+TCCCGGTGAAAATCGAAGGAATCGTCGCATTCTCAAAGTTTTTTCACCGA
+TTTGTTTCAATTTTAGCACAACTAAATGGAAAAATCACAAAAATTCCATT
+ACAGCCGATTTTCGTGAATTTTCCTACATTTCGAACTAAAAATTGTCCTT
+TCTTCTGTTTAAACCGGAAATTCTCTTTTGAAAAACCAATGAAAATTTGA
+ATTTTCTGGGCTTTTCTTCGGAAAATTATTCTCGAAATTTATCAATCGAT
+CCTTGGGCTTTTTTTGTTCCGCAGAGGCTGGCGGAGTTTACAAGCGTACG
+AAGTGGTTCAACTTTTATATAAAGCTTTATAAATGGGACATAGATGAATA
+TTTCGAATGCTAAATGCAAAAAGAATCAGTAAAAAAGCGCGCAGCCCCGT
+CCTTCTCTGACGAAAAACGCCGTTTAAGGATCGATTGCTAAATTTTGGCA
+GTAGTTAGAAGTGTCAAAATTTCTGCCGGAGAGTCGTCAAATTTCACTGA
+AACGTAACCCGGTAATTTCCACAATTAATGGTCGATTTTTCGCAAAAAGT
+GGTATGTTTGTCAGGATTTATTAGAAATTGTGGCTGTCCAGATTTTAAAG
+AGTATTTTTGGGCAAAAATGTCGAATTTTCTCTGAAAAAGTTCGATTTTT
+ATCGAAAATTCAGATTTTTTAGATAGTTTTCATCGATTTTCCCAGTTTTC
+AGCCTGAGAACTTTACTAACAGAAAGATGTGTCATGAGCACCACTTTCAT
+GATGCTCACGAGCTTCAGCTTCTTCATCTTCGTCCTCTTCATCCTCCAAA
+TCTTCATCCTCATCGCCCATTGATTCCCCAGACGTTGTTTCGCGTTTTCT
+CATGGATCTTATAGGACGAGCCATCTGAAGTTTCAATTTTAGCTTTTAAA
+TTCAATTTTACCGCTTAAAAATCGATAATTCTCCCGTACTCTGCTGGTTT
+CTTCTTCTTGTTCCGCCTGCTCCTCTGGATCATCTTCCTCCATTGGCTCC
+GGCGATGCATTCAACATATTCAAGCCTTCGTCTGAAATATCTGGCCAATT
+TATAGAAAAACCGACAAAATAATAAGCCTCACTTTCTTTTCGAGAGGCGT
+CTTCGTCAGATGACGTGTACGAATCCATTTTCTGGAATTTGAGGATTTTT
+GAATGTTTTTAAACAAACTTTATAGAGAAAACATTCGAAACACTAGAAGT
+TATGTTGAAACACGAGAAAATTTTTTAAAAATCCATGAGAAAAACAGTTT
+TGAAAAATCTGTTTTTGGAGGCTCTCCGGATTTTGAGGAATCGTCACCCC
+GGAGACGCAGATTCTCCGGTAATTTTTCATTCATATTTGAGTTTAAGAAC
+AAAACAGTTTAAAAAAATGTTTTTAGTATTTGAATGAAACTTATAATGTA
+TTTTTTCTTCCATTAAAACTTAAAAAAAACTACAAAATTATTATGAATCA
+AATTTGAAACCGTGAATCAATCTCCGCGGAAGGGCGAGTCTATACTGCTG
+CAAGCGCACTCTATCGCAAATGTACAATTGGCGGTTTTTCAAACAGGAAT
+TAATCGGATTCTCGTAGTTTATTTTGGATTTCTTTTTTCGGGAACATATT
+GGTGTTTTTGCGTTCAATATTCAAATTTAGAGGAAAACTGCTTCAAATAT
+TTAGGTAAACTCTTGAAACCGCTGAAAATAGGCAAAAATAATTATTTTTG
+TATTTTTTAGGCTACTTTCTATACTTTTGCGTAAATACTATAGTTTTTCT
+ATAAAACACCCATTAAAATTATTTTTATAAAATGATTTTTCCAATAAAAA
+TAAAATGCGCAAAATGATTCTTTTCCAGAATCCTATATGCGCCTTTAAAA
+TCTCTCGGATTACTGTAGTTTCAAAGAAATTATCCTTTATATTTTTAATT
+TTAAATTTTTTCCTGAATGTCAAATATTAGGGGAAAAATTATAATAATAT
+GTGCTTTATTCATATGAGTGTAGAATTAGTGAAAAAGAAAAAAAACATGT
+ATGGACTGTAAAATTGGAATTTTAGCGAGAAAATAAAAATAATATGCAGA
+AAAAATTAAAATTTTCAGGAAAAAAGTCAGTAAAGCCATCAAAAACTACT
+CGATTTTGAAGGAAATCAGCAAGAAAAATTAGAAAAAAGTATTTTTAAGT
+TGGAAAACCCCTGCTTGAATTTGTACACTAAATTGGGCATAAAAGCGTAC
+AAATTCGCAAAAACCGGTAAAAATCTGGGGATCGTGATGGATGGAGTGTT
+TTGTGAAAAAATGCAGCGAAAAATTGAGTAGACAATTTCAAAAATGTCGA
+TTTTTGAAATTTGTGACGAAAAAATTGAACAAAAACTGTTTTTTTTTGGA
+ATTTTCAACAAGAAGTTTTATAAATTTTTTTGTTTAAAATTTTGAATATT
+ATATGAGTTTGGTTTCACTTAACAGAACAATTCGAACAAAAGTATTCTAG
+AAAGGAAATGTGCGCTCCAGCACACTATTTGCCCGTGGAGCGCACTTGTG
+TGCACGAACGCTAGCGAGAATGTGTGGTAGAAAGGGAGGGAATAGGAAAT
+ATTAACAAAATTGGGCAAAATATGTAAGATTCGGAGAAAGAATTGGAGAA
+AAATATGTATTTCGAGCTCCGCGAGCTGATCAATCCAAAGGCTTTCTCCA
+TCCTTTTTTCGAGAGGCACATTGCATTATAGTTACACACAGCACGTGTAT
+AATGGAACATTGAAGCCTGGAAACGAGCCATCGCTACCATCATTACCACG
+TGGATCTGAAAAAATTAAAGTTTGATGATTCGAAAATTTTCTGGAAAAGT
+TATGATTGTGAGATAAATTGAATTCTTTGAAAAATCAAAATTCAAAAGCT
+TGTAGAAAATTTTATATATTTTTTTAAGCGTATTTTTTCCGTATACATTT
+CCAAATTTTTTTGTTACCCAATTTTAAAGATTTTCTTGAATTTTAAAATT
+TCTTTCAGTAAAAACTTTTTTTCAACTTTTTGATTTTTTTTCCGCATTTT
+TTAAAATTTTATTCAGAATTATTAGATTCTTTTGAATTTAACGAATTTTT
+TTCGCTAAAAAATTGTTCGATTTTTCCCGAATTAAGAAAAATATTATTTG
+GTTTTTGAATTATTTTCCTGATTTTTTTCGATTAATAAATTTGTAAAAAC
+AATTTTTTTTCTAATTTTTGGTTTTGATGATTGTGTTTTTTTTCTGAACT
+TTACAGTTTTCAAAGTTTACACCGAACTTCCACATTAAAAAATTCTGATA
+CAAAAAAGTATTCACATGATTTTTAAAATTTAAATATTTTTCAAAAAAAA
+TAATATTTAAACTGTGTTTTTTTCGGAATTTTTTTTCGATTTTTTCCGAG
+TTTTTTTTGGAATTTTTTCCTTTCTGCTCCAAAAATATTCAAATTCAATG
+TTGTGTAGAAATTTTATTCAAAAAAAGTGTTCAACTTCTGAGTCTAAACC
+TTTTCCGAATCCTTAAATCCTGGCAGAGCTCTCGTGAATTCAGTTGTCAA
+TTTATGTGGATAGCAAGCTGCCAGTTTAATGAAAGTTTTAGTTCCTTTGT
+CAAGTACTCGATTAATTTTCGAATAATCATAATCATCGACTCGAACACCA
+TATAATCCTTGAGTATAGTTCCAAATTGCTTCACGGAATGCAGCAGTGTC
+AATTTCATTCTGATTCACGGCGGCTGGTGGTTCTCCGTCTCCAGATGCAT
+GGGATGAGCCGGATGGCCTGAAAAATTAATTTTTTGGAATTATTATATTT
+TTCTGTTTTTGAAATTTCATGCATCTCGAATATTTTAACAAAATTACCAA
+ATTCAACTAGATTTCTTACAACTTTCACTGTGTCGATTTACGGGTTCGTT
+ATACGAATTGAATTTGTTTATCGATAGAATATTAAAATTTAGCTAAAATT
+GAGAAGAATATAAGAAGAAATTAATTTTTTTAATTTCAAAAATCGAGCCA
+GTAAATCGACACGAGCGATCGACACAGTAGTCATTTAAAGACCAGTTTCC
+GCCACGAAATATTTCGCGCTTCAAACATGTTGCGTAGTACGTATTCTCAA
+AATTGTGCGTTCACGTATAATATTTATGCGAATTTTTGGTCTACTTTGTT
+AGAGAAATCATCACTAACATATTGCCAGTAAGAGTCCGAATATGATCGAA
+CATTCGATCAAGCCGTGACGTCAGTGTATCCGTATACTCATTCATCGTAT
+TATAAACATGATCCCATCCAAATTCTTCAACTCGGAATGGCGGAATATCC
+TTTTCAGGTCGCTTTCTAAAATCAATATATCCAAATGTTCGATGATGCGA
+GTAAATTGGATAATTACACGGCGGCTCTTTTTCCATAATATCTTCTCCAT
+TTTCATCGATATTTGCAAGAAGAAGTACAGGCGAGTAGTTTTTCCGATTG
+GAACTATATGTTGCTGCAGGAGCACTAATTAATGATTCAATAGTTTCAGT
+AGTCATTGCACACATCTTCGCTGGTGGCCTAGTTTGTCCTTTTTCCGTCT
+TTTTCAGCTCACTGATCAAATATTCGACTTCAGTTGGCCGACGATCTGGG
+ACTTTTCGGAAATAGGCCGACATTCTCGCCTCCCAATAGTCGAGATCATC
+GATATTAAGGAAATCAATCTCATCTTGTGTCAAATCAACACGACGTTCCA
+ATCCAATACAGCATATAACTGTGCACATTGCGTGAGTCATTGACATTATT
+CCGACGGCGTGGTGGAGAGAGCAAACCGAGAAAAACGCAGGACCACCGTC
+TGGCGTGCGGCGAGCGAAGAGCACCTGGAAATTTTCAAATTCTTGAGAAA
+AACCTAACATCGTTGTTATACGTTCGTTCTCTTGGCATTGGAGTTGGCAG
+AATTTGTTTTGAAAAAACGTTGTTTTTTTTTTGAAAGAACATTTTTTTAT
+TACGGGACCATGAGATCATGAGAATTCCTATTTACTGGCGCGAAAATATT
+GGCAGGCCACGGCAACGAGAGAGCATATGGCAAAGAGAGACGCATCTTAT
+TTTGTCTTGTAATTTTTTTTTAAAATAATTTACAATCCCTTTTCAACTAT
+CGTGATTGTAAAATATTACAAATTTCAGAATTTCGCTACCAAATTATTAC
+TGGAAAACTAAACTCTGAGAATGCGCATTGAGCAACATATTTGACGCGCA
+AAGCATCTCGTAGCGAAAACTACAGTTATTCTTTAAATGACTACTGTAGC
+GCTTGTGTCGATTTACGGGTTCGGTTTTTGAAATAATTTTCTTTTCGAGA
+AGTGACAGTGATATTCCATTTTCCTTCTTTTCTTCCTATTATTTTATCAT
+TATTTGCTTAATTTTAATATTCAATTCATAACTAAATTACTTTAATTCAT
+TTCGAGTAGACATTCAAAGAATTCCGGTAGTTTTCGCTTCGAGATATTTT
+GCGCGTGAAATATGTTGTGAAATACGCATTCTTAGAATATGGTGTTCCCG
+TAATATTCAGAAAAGAAAAGATTTCCAAGAACTTTCTGAAGATTTCAATA
+TTTGCAAAATCAGAAACCAGTTCTGAATATTCTTTATTTTTAGAAATTTT
+TCAAGGTTTTCTAAATAACTTTTCTAAATAACCTACCGTATTTCTTCTAT
+TAATATGGCTGCAATACTATTTTTCGATGGTCTTCCCGCTTGCAATACTA
+TTAGGGAGTGCAAGTCTAATAGGGAGTGCCATACTATTCTTCAGAAAATT
+TTTCTGTGTTGGGGCTTACTAGATTCTACTTGAAAAAACTCCAATTTTAT
+TTGGAAGTATAGAAAATTTGATTGAAATTGCAACAAAAAGGTACAATAAC
+TTCAATCTCTAAAAATTTTGTTATAAACTGTTGCAAAATAGGCAAAAAAT
+GTTATTAAAATTTTAAAATTAGTAAGGAGTGTTTGCAACAAAAAAAAGTA
+GGTGCAAGACTATTAGGGAGTGCAACACTAATAGGGAGTGCAATACTAAT
+TTTCGGAAGGTCTCCGAGGGGCAATACTAATAGGGAGTGCAAATCTAATA
+GGGAGGCCATATTAATAGAAGATATACGGTATATATAGCTTTGAAAAATC
+GGAAAATGCCTAATTTTTACTTTTTGAGGTTTGAAAATCTCTAAAAATTC
+AATAAAATTTCAAATTACCGCTAGATTTTTCCAATGAATCATCCATGGTC
+TATGACAGAGCATTCGATTCAAATAATCCAATTTTCGAAATTTCATGTAT
+GACCAATCAATGCCCAACAACCACATTTGTTGTCCACCCTTTTCCAGAAA
+TTTGCGACGATGATGATCCATAAGTGATAGGCATCTGTGACGTGATGCAG
+CCATTAGTGCAAGATAATGACGAGCCGAAGCTGGTAGATCACTTATATCA
+ACGAACATATGGCCATAACTTCCTGTCATATGAACATGTAGAGTTGGGTG
+TTTACATGTGAAACGGAATAATCTGGAAACGTGAGGGAAATTAGTTCGAG
+ACGGGGAGGGGCAGGTTGGCGGTGCCAACCGACAGCCGAACATTGGGGTT
+TCTCAGCTGGTAGCGCCAGCCGACAGTCTACTGCAGTACTGCAGATAAAT
+TTTCGTCGGCTGTCGGCTGGTGAAAATTTTCATGAAAATCAATAATTTTA
+AAGAAATTGTTGCAAATTTTTCCCAAACTTGACCAAATTTGTTGGCTGGC
+TGTACCAGCCGACACCCGAAATTTAGAACATTGATTAGAGGCTGCTTGGC
+AGAAATAATTTTAAATTCAGAAATTCAATTCGTTTTCAAAAAATATTTTT
+TAAAACTTTACCGATCAACTTCTGGAATCGGATCAAAATTGAGCCAATCC
+ATGGCTTTTCGTCTTTTAGTTGTAGTGTGCATTGTGTAGATCTTTTTATA
+TTGCTGCGAGGTGAGTAAATGAAGAATTTTCGCGACCCGTTTCTGAAAAA
+ACTCAGTTTTCTAAGGAAATTTTGAAAATAAATTCGAGAAAAAGAAACTG
+AGTCAGCAAAAGAAAATTGGAAATGTCTGTCTGGAAATATTCGAATATTA
+TATTCAAAAGTTTTCAAAAAAACAACGAAATTACAAGCAATTGTGATCAG
+AAACCGCGGAAGGAACTGGACGAAAAAAATTATCTTTGAGACGAATCTCT
+TTGCATCTTTGTGATCTAAAAGATTAATAAAGGTTGTCATCACATTTTTC
+GAGATTTGGGAATGTGATAAGGGTGAAAAATGGAGATTAATTGTGGTAAA
+ATGAGGAAAAACCTAATTTTTGGTGAGAAAATTGTGGAAAAACTATAAAA
+GAATCTTTATGGAGTTTAAAACTCAAGTTTTTCACGCTTTTCCGCACTGT
+GCGGAACGTTTTTTGAGAGAATTTGGCCGAATTCGGTGATTAAAAAAATA
+ATTTCAAAACTTTGCGCCTCAATTGTGATGTATTACCGTACTCTGTTGCC
+ATTCCACCAAAATTTCCTTCATTGTTTTGCCATTTTTCTGCATAATAACT
+GTTCTGGGTTTTTTTGCTTCATGTGCCCAAATGTACGAATTTCCCTAAAA
+ATTATACCTATTTTTTCAAAATTTTTAATCGCTAGAATTTTTTTTTCTGC
+ATTTTCTTTAAAAAAAGAGATTTCTCGCAAGTAGAAGGAGAAAAAATGTG
+TGGCTATACTTCTTCTTAAAGAATGCACGACTAGCCATAGCTCAAGCCCC
+CTCTGGAACGTTCCATCTTCCTCCCATTTTCCCACGTTCAAGAATCATCA
+GCTTCTTCTCCCTCAGCTTCTCTTCTTCTAAAACCACAACTAGACAAATG
+TTCTTGTTTTCCACCCTATTTTTCACATAAAACCGCCGAGAAACCCGCTA
+TCACAGACTCAATGCGCACCGGAGGGGCTCTTTGTGTGTGTGTACTGATC
+TCTGCGTTATATTCGAACACCGGCGCACACTCGGATTGAACCAGAGGGGG
+GGGGGGAGGGGGGGGGGGGGGTGAAAAAAGAGAAATACTCTGAAATTCCA
+TAAAATCTAGAAGAAGAAAGAAAACAAAGGAAAAATTGGACATTCCGAAG
+TCAGGCTAAAAAATCTCATAAAACAAAATCTATTCGATTTGTGACCATTT
+TCATCTATCTCTCTCAAAACCCGAATAAACAAAGCCTCCCGTCCCCAAAG
+TGTGCTCTCATGCTCTTCTGGAGCCTTCTAGACTGTCTGTAGAGCCTAGA
+GACAGCGGAATTGCACTGAAGTGATGGAGAGACGTAGAGAAAACGCCTGA
+AGAAAAAAACGAACACTTTGGTGGAGGAGGAGATGGCTTCCCTCCAAATA
+AACAACAATTTCTATCGTTTCTCTGTGATTGTGTTCTCTTCTATGTATAC
+TGTTACGATATTGAACAGGAAATTAAATTGAGCACTCTGAATACATAATA
+CACAATAAATAAATACAAAAACTATAGTTTCAGCACAAAAAATTCGAAAA
+AAAAACGATTTTTTTTGTCCGAGAGGAGTATATGGCCTAGAAAAAGAAAA
+CTCGGCCACTCTGATGCAATAAATTTAAAAAATTATGGCCGAATTTTAGA
+TTTCTCAGGCCAATTTGATACGTTTCTCGAAAAGCCATAAATTAGTCGGT
+TTTTCACGGGCTTCTTGCCTTCCTCATTGCATTTTTCGCGCTCCATTGGC
+AATCTCCTGCTGGACAACGCGTGGGAAATCGTGTGCCCCACACGGGCAAA
+TACATTTTGTTTTACAAAGAAAACCGTGCCGCGACGCGACACGCAACGAG
+CCGTAAATCTACCCCAGATATGGCCGAGCTCAAATGGCCTAACCTGTCAA
+AATCTTCCACTTCAAAATATGAGGGAAGCCAGAAGCGCGTGTTGTTTCTG
+AAAAAAAAACCCGCCTAAAGTTGATTTAAATTATCGTTTTTTTGGAAATA
+ATAAAATCGATGAATTTGTAGATTTTGATAAATTTCCGATAAAAAAAAAA
+TTTTAAAAGAGGAAAAAAAATGTTTCTTCGCCCTTTAGTACCAAAAATAC
+GCCCAACTAACCAAATCGTTCTTTCAATCTTTTTTAAATGTTTGTGCGTC
+TATAATTGTCGCTTCAGAAAACTACACAAAACACACACACACACAAGGAG
+AAGAAAAGAAAAAACGTGTTCCATGACCTGCCACTGGGATCGATCTGTAA
+AAGAATTGGGGAAAATTGAGGTAAACTGGTTTTTTATCGGGAAGATTTTT
+TCGGAAGGATTGAGATGAAAGTTCGAAAGGTAATTGGCAAAGTTGAAAAT
+TGAAAAATTCGAAAAAAATCTCAATTCTCTGCTGTAACCCCCAATTTTGC
+GTCATGGCCTAGAGTATGCAGCGTGGCCTAGAAATTCCTAACGTGGCCTA
+AAAGATCACGGCGGTACCTATGATTTTCTAGCGTGACCTAGAATATACCA
+GACCTAGAATTTGATAGCGTAGAATTTCCCAGTATATCCTAGCAGTCTTA
+AGTGACAGTTTCTCAGTACGTCCAAGAATTCGTCAGCATGACCTAGGATG
+TTAAAGCGTGGCCTACAAATTTTCAGAGTCTTCTAGGATATTCCAGTCTA
+AAAATTTTCAGTGAGGCCTGAAATCATCGCGTGTCCTAGAATGTCTAATA
+ATTGCAAAAAAAAGATTTGAAAACTAGTATTTACCCTAAAATTGCATTTT
+GAGCATTATTTTTAATCTAGTTTTAAGGAAAAAATCAGAAAAAATAAACA
+TTTTTTGATTAAATCTTCCGATCTACAGATAGAAAGTGTGCAAGAAAGAA
+TGCAACATTGTGCTCGGTGGAGCAAGAAGATAAAAGAAAGAGAAAGAAGG
+TCCCCCACCCCTCCAGTGGTCGAAACAATGATAAATTGGACAAACGGAGG
+ACCAAGGGGCCGGGCAGACACAAGAGAGAGAGTACGTGAACTGAGGAGGG
+TGTGCAGGGAAAAATGGGATGGGGGCAAATCTAGTTCAAAGATGAGACAC
+TTTTCAGGATCTTTGATTCTGAGAAAAATTTTGAACAAAAAGAATACTTC
+AATAATTTAATGGCACATAGAAATATTTTCAGATTGTTCTTCAAAAGAAA
+AATATTTTTATGCCCGGAAAATTTATTTATTGCATTTCTTCCAAAACAGT
+GGCCGGTCTCGACACGACAAATTTTTGTTAAATGCGAAGAGGTGTGCGCC
+TTTAAAGAGTACTGTAATTTCAAACTTTCGTTTTAATATTTACTTGTGGG
+AAAACATTAATGCTTAACGAAAAATTACAGTACTCTTTAAAAGCGCACAT
+CTTTTCGCATGTGACAAACATTTTCGCGTCTCGGTGACAACTTTTAAGTT
+AAAGGCACATAGAACTTTTCTGAAGAATTTTATTTATTTTTCTGAAAGTT
+AATTGCTACAGTATCCTTTTTCAAGTCGCACCGAGAGCCAAACTGTAGCA
+AATCATCAAAAAAAAGTCGACAAAACGTGCCGAAATCAGTAAACTTGAGA
+GCTTTAAAACTCTATTATCAGTTCTTCGCCAACAAAAAAAAAGAGTACCG
+TATCAAAAACGAACTTCGACTTTTTTGGCTCTCCTGCATACGGACATGAT
+TCTGATTGACAGTTTTCATGTTTTTTTTTGGGAGTTTTATTTATTGTGCA
+TTTAAAAAATCGTATAGTTTGATGCGTGGCCTAGAATTTGCCAGTGTGAG
+CATTAACTCTCCACGGTAGCCAAGAAATTTTCTACGGTGGCCTAAAAACT
+GCCAGTGTAGCCTAAAATATTTTATTGTGGCCTAAATTTTCCAATGGTCT
+GTTTTTTTTATAGTTGCCTAGAATTTCTTTTCGTGACCTAGAAGCGTACA
+GAGTGGTGGCCTAGAAAACGATTCATGGCAGAGTTTTGAAAAAAAAACGA
+AATTTCGAGAAACAAGCGAACAAAAATCGTCTGTCGAAAGAGTATTTCGA
+ATGCTGGGGATGCAAATCAGCAAATCATTCAAAAAAAACTTTTGTGATAA
+GAAATCAAACTGATAAGCCAGTGTCAAAGTCTCGAGGATTAAAAATAGCA
+TTTCAGGTCGGGGTACGGTAGGGTTTTTGTAGAAATTAATGCAAAATTTC
+AGTGGGAAACGAGTTCGTGGCCTAGAAAAATCATGTCTGAAAAATTGCAA
+ATGCGCTCCCCCGAAATGGTTAAAAATTTTCAATTGATAGCCTATTTGAA
+GTGGCGGCCTAGAATATCAAATAATGGCCTAGAACTCAAATTGGCGGCCT
+AGAAATCAAACTAATGACCTAGATTAGGGCATCTTGTAGGCAGCTTAGAT
+CACCTATTATAGGCAGGTGTAGGTAAAATTGTAGACAAATGTAAGTTTCT
+TTGAAGATAGGCGTAGGTTCCTTTGCAGGCATACATAGATCATTTATTAG
+GCAGATGTAGGCCTGATTGTAGGTACAGTGCCGGCCAAAAATATATCCTA
+TTTTTGACTTTTGATAAATTTACAAATTTTCCAAACGAGCACAACTTTAA
+AACTAGAAATGTTATCGAAAAAAGTTCAACTCATGTATGTATTGCCCATA
+ATTACGTCTACTCGTATTCAATTGTTTGTTGTTTACTAGTGTCACGACAA
+CAAATACAGCGGCCGACATCTCGTAAGCCCGTTTTTGACAACGTTTACTG
+ATTCGGCCGTATCTCGAAAACTAATTTTTTTCTGAAAATGTTGTTAAAGT
+GAAATAGTTTTCATGTTATTTGTTATCATTTGTGTTTATTCACTTTGTTC
+TGAAAAATCCAGTAAAAAAGTTATGGGAGTGCAAACTTGTCGCTCACTGC
+CACTCACCCGCTACAATCAAAAATCAGGTTACTTATAGTTAGTTCTAATT
+TTTTTTTTGTAGAGCATTTTTTAGAAATAACACATGTAAAATCACAATGA
+AGCTATATTCAAACACGATATCAAGATTCAGGAAAAAATTCATTGTTTGC
+GAGAAATGTTCAAGGCGTGGCCAAACACTATTCAAGTTTAATCTCTCATA
+ACTCTTTTTCTGGATTTTTCAGAACAAAGTGAATAGACATAAATGATGAC
+AAGTAGTATGAAAACTATTTCACTTTAACAACACCTCGAAAAAAAAATCG
+CTCTCGAGATACGGCCGAATCAGTAAACGTTGTCAAAAACGGGCTCACGA
+GATGTCGGCCGCTGTATTTTTTGTCGTGGCACTGGTAAAAAACTTAAAAA
+ATTGAATACAAGTAGACGCAATTATGGGCAATACTTCATCAGTTAAACTT
+TTTTCGATAACATTTCTAGTTTTAAAGTTTTGCTCGTTTGGAAAAGTTGT
+AAAGTTATCAAAAATCGAAAATGGCATATGTTTTTGGCCGGCCCTGTAGG
+TTAAATATTTTCGTTATCAGGTGTAGGCATGAATCGCCATGTAGGCGGGC
+GTAGGTATCTTCTAGGTAGGCGTAGGTTACCTGAGTCAAATTATAGGCAG
+ACGTAAGTAATCATAAAAATTGACACTTTGTGGGCAGGCGTAGGTCACCT
+TTTAGACAATCATAGTTAGCTTTCTAAGTAGGGTTAGGACACCTATTATA
+GGCAGGTTTAATTCCTCTTATATGTGTGCGTAGAACACGTTATAGTCAGG
+TGTAGGTCACTTTGTAGGCAAGTCTAGGTTCTTCTTTCGGCAGGCGAAGG
+TCATCTTCTGAGCAAGTTAAGGTTCGCCTTGTAGGTCGGTGTAGGTTGCC
+TCGTAGGCAGACTAAGTTACCTTCTGGGCATGCCTAGATTGACTAGTAGG
+CAGGTGTTGGCACCAAGGGTGTCAGTGTCCCGTAAAAATTACAAAAACGG
+GACAACGGGATGTCCCGTTCCCGTGAAAATTTTAAAAACGGGACAACGGG
+ACGTCCCGTTCCCACGAAAACACCCAAAAAACGGGACAACGGGACATCCC
+GTTCCCGTGAAAACGCTCAAAAACGGGACAAAAGACGTCCCGTTCCCGTA
+AAAATGACAAAAACGGGACACCGGGACGTCCCGTTCCCGTGATAATTTTG
+AAAACGGGACAACGGGACGTCCCGTTCCCGTGAAAACACCCAAAAAACAC
+CCAAAAAAACGGGACAACGGGACAAACGGGACACGGGACTTGACACCCTT
+GGTTGGCACCACTGAAGAATGCTGAAACCGACTTTTTTTTCAAAAATGTC
+CTGCTCAACGAGCCGAATGCATTTTGGTCGGATTATATTGGCACACCTTT
+TTGCCCCCGAGAGAATCATTGAACAAAATCTCATGCACTTTCAATTTCAT
+TTTTCATTTCATCAAATAAAAAGATTCGGGAGGATTTGATATATATTGGA
+AAAATAAATGAATGGGGGATTTGTATGGTGGGGGAAAAGTGCACACCCGG
+AAATGAGCAGTAGGATTTTGAGCAGGAAATTGAAGGAGCTGGAGCAGGAG
+AGCAGCTACAGTAACCACCCCTTCACAGCAAAACACATGGCTCATAAAAT
+TGAATATTTGAAGTGAACTACTAGTGATAAGCGGTGAAACGGGGTATGTG
+GCACTAATTTTTTTTTCTTCAAAAAACCCATTTCTTATCACTTGTGTGCA
+GAAGCATTATGGAGACAGGCAGGAGGCAAGTGGTGGTCTAAAAATTAGAA
+AAGTTCGGCCACAGCTTGCCCGATAGGAGCACACGGGCATACTGTTTCAA
+CAAAAATTCGAAAAAATTGGAAAATCCCGGAATTTTGATTCCGCGGAATC
+CGACGATTAAAGAAATTCTCGCGTTTCTGATTTCACGGAAATCGGTATTC
+TCGAAATTTGGTTTCTGCGGTGTCTATTGTTTTGGAAATGTTGTGTTCAT
+GTTTTATGAAGAACAATATAATATTATGTATAATAGATATTATATATTAT
+ATATAATAGAATAATTTTAGTAAAAACCCCACAAAACTTCGAAAATAGAA
+GAAATTCTCGCGTGTCTCCAAAATTACAAAAAAATCAGTTTTTTTCCTTT
+ATTTTATATTACACAGGATATTTATATCAATTCAGCAAAAAAACGGGCGG
+GACAGAAAATTAAGAAATTTGCGAATATTCGTTCCCACGGAAGTAAATTT
+CCCCGAATTAGAAAAAATTCGAATTTTTACTGGATTTGTCTCAAGCTTTT
+GAATCTAGAAACATTTTCTAGTAAAATCTCTTTAAAAAATTTTTTACACC
+AAAAAACTTTTTAGGCCCTGAATTCTGCGAATTAAAAAATTCCGCAAGAG
+ACCACACAAAATCGAGAGACTTAGTTAGACAAGTAGAGGGAAAAATAAGA
+GGCAACAAATCATCGAAAGTTTTTTTCTGCAGAGAGAATGGGGGAGAAGT
+TGCGGCGCTGAAAGAGAGAGAAAGAGAGAGAGAGACAGAGAGGGTGAGAG
+ATATAACAGAAAACCAGGATAGTGCGGAGGAAGAGAAGAAAAAAGTGTTA
+GAAATATTTGTCCGTCGACGCCTTCTTCGTCTTCTTCGTCGCCTTCATAA
+ATGAAACTATGCATTTTCCTCAGATATTGCCTTACTATTAAATGGGGCCC
+GGGCTAAAGGGTGTGGCCGGCCGATCCAAAACGGTGGCCTAGAAAAATAT
+CGGCGGTGGCCGATATCAAATAAAAAAAACATCGATAGTTATGAGACCAT
+AATTTTTAGTTTTTCAGATTTTGAGTCACTTTTCTGATTTTTATCCCAAA
+AATAGAGCTCTTTGCTGTTTTTCTGCAGAATCAGCAGGTGGCAACTTGGT
+TTTCGGAATTTGTGCTATTCTTAGAAATTCCCGACACAGCATCGAGTTTT
+ACTGGAGAACACGTAGCGAGCACAGAAAAAGGAAGGAAAGACAAGAATTG
+GCTCGGCGAGCAACCAGAAAAGCAGCAAGAAAAAACTGACCGAGCAAAGA
+ACAGCGCGATGGGGCTCATATATATCTAAAAATGGATGGATGGAGAGATG
+AGAGACAGCAGCAGTATTCGGTCAAATGAAGACAAGCCAATTTCGAAGCT
+TATTTGGTATTCATGCGTGTCTTTTTTTTTCTTGCAAGAAAAACTGATCA
+TTAGCAGAAAATTCAAAAAATATTGGTTGTCCGAGAGGAGTACAGAAATT
+AAAAAAAATCGTCCGAAAGGAGTACAAAATTCAAAATGTCTATTATCCAA
+GAGAAGTACAAAATTCAAAAGTGTATATTGTCCGAGAGGAGTACAAGATC
+CAAAATATGAATTGTCCGAGAGGAGTAAAAATTCAAACCACAAAAATCCG
+AATTTGCCAAGAAAGGGGCGGAGCCTGATTCGAGTGGAGTGTCGTTGCAA
+AACGCAAAACTTCAAAAACATACGGTTTTCAAAATCTACCTCGCCGACCT
+ACCGTAACCCTCTAAAATTTCTAGGATCAAATATCATCGCAAGAAAAGTG
+TTCGTTCGAAACGAAAAATATTTCTGACGCCTCATCAATCATCATATCAG
+TAACAAAAACCTGAGAGAGACGGAAACAAAGAAATATATTTTGAACCGAA
+CAGGGATCCTGCAACAAATCACGTAATGGACAAAATGCGCCCTATTGCTA
+AATATGCAGCAAGACGCAATTGCATTCTTCTGCCAGAATATCGATTTTTA
+TACGTACTTATAGTGATAAAAAAAATGCTGAATTATCGATTTTTAATTCC
+CCGGAAAAATGTGCGACAGAGCGTGTTTGCATTTTTTTTTTCGAATTTTC
+GTGCAGAAAAACCCGTAAGCATCGATTTTTCTCAGTAAAAATTTCTCGCG
+CCAAAATTGTTTCTATTTTTTTCGGGAAAAATCGAAAATCTCCAAAACTT
+CGGTGGAGCGCACTTTCTGGACCACAATTTTTGAAGGGAAACATCACTTT
+CTGCGGTTTTCAATAAACGAACAAACATCAACAAGAAACGAGAGAGAGTT
+TTTGTTGACTTTCAAGAAAAAAATGGATATCGAATTTCTGTGCTCCATTT
+CCCTCTCCGGGAAATGGCGCGGGGAACGTGCAAACAATGCGAGTATGTCT
+AATGGCTCTCACGTAGATCGAGAAAGTGGAAAATTTGCTAGTATAGACAG
+TTTAAGGAGGCTCTTTTATTCTATTGGGGAACCGATTTGTTTATGTCTTG
+CCGTGGAGCGTAGTTACTGTAATTTTTTTGCAAACGTGCTCCATCGAACA
+GTAAAAAAATCAGTATGCATACTAGTATGTACCTTTAAATAGCTGTAACA
+CGAATTGCCTGTGAAAATAAAAATCTCGGCAAGTTCTCTCCATCGGATCA
+ATGTAGGGAATTTTGCTGTTTATAATGCAAACTCGCTCTAATAAACTACA
+ATTTTCGATCGGTATTTCATGCATTTCGACTGATTTTCGTTATTTTTTAT
+GTACGCTCTCTATTGAAACACGGGGCCCGAGAAAATATCCAAAATCTAGA
+GAGGTTGTATTGCTTAGGCTTAGCCGAAAACCTGTAAAGATTTTTTAAAA
+ATTGTTCAGCCTGCGATGGACGACTTTTTGTAAAACTTGGCCACCAACTT
+TTTTACGGTGCGGCTACATCGCATTTGGGTGACCTTTAATGTGTTCAGGG
+TGTCTAAACATGCACCCAAAAGAGAGTGTCATTTTTAACGCGAAACAGCA
+TCAATCCAAACGGGGCGACAAAAAATGAGAGAGAGAGAGAGAGCGGGCGC
+AATCTAATGTTTTATCAAGTGTCTCTTCTTCTCCTCCGACCTCGTTTGCA
+TCCCCCTAATTCATCATTCGTCGGTTTGTAATACAGAGAGAGGGACATAG
+TGAGTGAGAGGGAAAATTGAGGAGATTCAGAGAGTTAGAAAGAGAGAGTG
+AGAGGGAACTTCAACTTTTTTTTTCAAAAGTTTTGGTCGATGATTTTGAC
+ATTTGATAAAACTGAATGAGAGATGATGCTTAGATAAATGAAAATTGATG
+AGATGATATTTATAAATGCACTTGCGATGTTGTTTTACGTGCAAATTGCT
+GATTAGTCGAGAAGTTGTGATTTTCGTGTCGGGAATATTTCACTAGGAAC
+GCCCTTGCGCCTTTAAAATGTAAAGTAGCATAATTTATTTTCAGAAAATT
+TAAGCGTTGGAAAAATAAGTAGTGCGCAACATATTTGACTCCCAAAATGT
+TTTGTAGCGAAAACTACAGTAACTCTTTAAACGAATACTGTGGTTCTGGT
+GTCGAGTTACGGGCTGCCAAAATTCGAAAGTAAATTCATTTATAATCGAA
+CCCGTAAATCGACACAAGCGCTGCAGAAGTCATTCGAAGAATTACTGTTG
+TTTTCGCTACTAGATATTTTGCGCGTCAAACATGTTGCGCAGTACACATT
+CTCAGAATTTTGTGTTCCCGTGATATAACAATTCATTTTTCTGTCTATAA
+CCTCTTTCAATTATAAGAAACCATTTGCAGCGAAACACAAAAAATTTAGC
+CGATTTCTATTTCACCTATAAAATTCGCGTCAAATGGCCCGCGCTGTCAA
+GACAGTCATAAAACCAAATGTTATGCAAATGGCGTAAAATTCAACAGTGC
+CCGCCCGCATGGTCATTGATCGTTTAAGAAGAATGGAGGAGGGTGCGGGG
+AGCATCATTTCCTGAAATGAGCCCAGAAGCGAGAGATTAGAGAATTAGAG
+AAATGAGAGATCAATGAGGAGAGGGTGAAAGGTATGAACAATGAATAAGA
+AAGGGATGGAAATGATCACAGATGGAAATAGATGGAATAATGAAGTGCAT
+CGATGCACCATTTCAGATTTTTCGGGCTTTTCGCAGATAATTGAGGAATT
+ACATTTTTCGGGCTCCATCGATAATACCCTGCCGGACAACGCGTTGGAAA
+GTGTGTGTACTCCACACGGGCAAATACCTTTAGTTTTACAATGAAACCCG
+AGCCGCGACCCGACACGCAACGCGCCGTAAATCGACCCCAGCCGTGGCCG
+AACCAAAATGGCCTAATTCGTCAAACTTTTACATTCCAAAATATCAGGGA
+AACCAGAAGTGCGCGTTTCCTGTTGTCCGAAAAAAGATTACAACAAAAAA
+GAAGAAATGGAGCATTTGCGCTCCATCACACTCTCAGACAATTTCATTTT
+CCACATCCTATATATATTTTGGTTTTTCTGTCGTATTTTGTTTTAATTTA
+TTGGTATTTCGTTCAAAAATAATTATTTTGACTGTATTTTTGGTTGCATA
+CATGTAGAACTGCTGTTTTTTAAGATATTCTGCCCATTCAAGTTTTTCAG
+TGTAAAATTGATATATTTCATTCCAACTGAAAATGAGATCGAAACGATGG
+AAAACCTCGGATATTACTGATTATGGAAAGAAGAGAAAAGAATCGGAAAG
+TTGTGGATCAAGTTCACCGATTCTCGAAACACAGTCATCTGGCGGTGCGG
+AACTTGACGAAGTTACTGAGGATGAATATTCTAGTAATTCGAGCAGTAAT
+GAAACTAGCGACGAAGAGGAAAACTCAGAAGTACCAAATGTCTTATCTAT
+AACAGAAAGAGGTAAGAATTGCGTCTTCTAGTGATCATACTTTTCGCCAG
+ATTCCCTAATGTAATATATTTTGTTGTAGAGAAAAGTTGGCAAAAGTTAA
+CGGAAAACGATTTGGGACGAATTCGTTTCATCTTGAAGTACACTAGCAAT
+ACTAAAAAATGCGTGAACGAGTATTTTCAATATAATCATGGGCAAAACAA
+TGAAATTATGAAAAGTCTATTATTGGATACCGATGGAACTATGACTGCAA
+AGGCTTGTTCGGAATGTGCCTACGATTTGAATCAGTAAGTTACTCTCTCG
+ATTTATTCCCAAAATTAATATGTGCTTCAGGTGCCACTGCAAAAAACCGC
+TTCGCTTCATCAATGCTCCGTGTGGTTGGTTTGCTATTCAAAACTATAAA
+TAGTTCACTGTTTCCGTTCAGAGGTCATCAACCAAGTTCTTCATGTTGAA
+AATGCGGAGCCCACCAGGATCAACCATGTAATCGCAACACTCTTCCGGAA
+TCACATTGGCGAGATTTTGTTGGTCCACTCTATTTCTGTGCGAGAACTGT
+GATAAAACTAGTATTTTCAGCACAAAGGCTCGAACTGCGGAAGCTCGCGC
+ATCTGAAGAAGCTCAAATCAGGATTCAAATCCAAGACAACTCGAACGCAT
+TCCAAAGATCGTATCATAACGATCCACAACCTTCATCAGCCGAAGAACAT
+GAGGAAGATATCGTGGTGGATGGCTGAGTACGGAGCTCAAATGCCTTAAG
+GCGAAACAATTGGTTTTTTAATTTGCTGGTTATCATGTTAGATTTTGAAC
+GTGTTAGGTCTTTCAATTGTTTTTTTTTTTCGAAATGTTGTTGTTCTAAT
+AAATTTGTTTTATTTAATCAAACGTTTTTTAGTCTACTACGGGCGTGAAG
+CCAGATATCAGTGGTATCTTCTTATCAGAAGCTGAATCATTTCCGGTTGA
+CAATGTTTGAAGGACATAAGAAAGGCTGTGTTACTGATTTCGACCATTGA
+TTTGTTTATATATGGATATGTTCCACTGCCTTTTGGAAAGGCAGTATTCC
+CGGTATATATGGGCCTAATACGGAATCTAAAATAACCTGACACAAACCTG
+ACGTTGACCTGTTGCCGGCCCGCGGCGGCTTAGTGTCAACTTGACAGCGG
+GTCGCGATTTCACCTGCCAGTTGTTCTCCATTCAGCAGCCAGCGACCTGC
+TGGCAGGTTGCCACTAACCTGACGCGGTTTACCTGTGTTATCGGCGCGTG
+CATAGCTTAGTGGTTTCAGGAAATGATGCTAGTAATCAGAAGATCGGGGT
+TCGGGAAACGGCAGGGGCTTGAAGGTTAGGTTCTATGAAGCAGGGCGAAG
+GGTTGACAAGGAGAGGCAATAAGCAAGTAGTAGGGGTTCTCTAGAAAACA
+TTTTTGTCTTTAATATGCGTTTCCTACTGATTTATTATTGATATTTGGAT
+CCCCTTTTCTAGAAAAAAAAATCAGAATCAGCAGAAAAATTTGAGAAAAA
+GTCATAGCAAATCAGAGTTGGTCAGAGTAAATCAGAGCTAGTCATAGTAA
+ATCATAGCTAGTCAGAGAATATCAGAGTTAATCAGGGTAATAAGTAGACC
+TAGTCATAGTAAATCAGAGCTAGGCATAGTAAAGCGTGGTTACTCCGAGT
+AAAACCACACTTGCACCGAACTGCGGTTAGTGTGCTTTACCATTATGTAA
+CTCCGCTTTTTACTCTGAGTTAGTATGATATGGTTTGTCTGAGCTGTGGT
+TGGGCTTCGCGGGAAACTTGAATAATTCGAGACAAAATCTAATTTTAGCG
+AATTTTCTTTAATTTCTTTGAGGTTTCTACGACAGAACTCGAAAAATTTC
+GGGTTTTAATGTTTACACATTTTATTTAAAATTGAATAATCAACTGCGGG
+ACTCCTCGAAAATCACATGCTCATTTAAATTTTGAAGTTCAAACCTCAAA
+AAACGCGCAAAAACCAAATTCAGCTAGGATATCAAATTTATGATTGAAAT
+CTATATTTTGATGCGGTGTTTCTGAAGTTTTCGCGATAAAATCCGAATAA
+TAATTCCACGTACCGTATATTCTCTATCTAATTTCCAGGTCATTTTTTAA
+TGCAGCACTATTAGAGACTGTCGTACTACTGGAGACTGCAGCATTAATTT
+TCGAACGGCTACTGTCAATTATAGATCACTAGTATTTAGTCACAAAAGCT
+AATTTTTTAAGCAGAAATTCATAAAAATGTTTTCAATATTGCGAACTTTT
+GTAACAAAAAGACCCAGTAATTCAATTACTTTCGTAAATTATCAAAAAAT
+CATCAAAAATATACAAAAAAATACCAAAAAATATTGAAACTTTCAAGTGA
+CTCTTTCAATAGAAAATGGGGTGCAGCACTAATAGAGACTGCTGCACTAT
+TTTTCGGACCCTTTTTGAATGCAGCACTATTAGAGACTGCAGTATTTACT
+ACTGGAGATGCAGCACTAATAGAGAATATACGGTATATACGTAATATATT
+CTTGCAGAAAAAAGTACGATTATCAATGAAAAATAGCTGATAAGAGGCTT
+TTGTTTGAACTAACAGACGGAACGACTCCGGTTTAGTTCAAAAAATTCTA
+AAAACACGTTGTGTCAGGCTGTCTCATTGCGGTTTGATCTACGAAAAATG
+CGGGAATATTTTTCCAGAAAAATTGTGACGTCAGCACGCTCTTAACCATG
+CGAAACGAGATGAGATGTCTGCGTCTCTTTTCCCGCATTTTTCGAAGATC
+AAAACGAATGGGACTTTCTGACTCCACGTGTAAAAAGGGGTTACGACGGA
+CCCTGGCCTAGAAATTAGGCGTGAAAATTCTCGGGCACTGGATGTAGTGA
+ACGCCCGCGATGAAAAATTGGGGGAAAATTAGGCTTTCTTTGCGAGAAAG
+ATTAATTAAAAATGTTTTCCTTTGTCGAAAATAATTTTTAAAAAACACAC
+CACGTGTATTCAGCTCGACCAACGCCTCGAAAATTTTCAAAAAAGGCGGG
+AAAAATTAGTTGAATTCGCCAAGAGGAATTTCACCGCAGCGCGTGCAAAA
+ATTTCAGCATTTGCGCGTGACGGTGTTTGCACAAATTACACCGAATGGTC
+GAGCTGAAAACACGTGCACACTTTTAAATAAAACTAGAAAATAAATCCCA
+GGCCTGCAAATATTGCACACAAAACCGTAATCCCCTTCGCGCTAAACAAC
+ACGCGCAACGATGCTCCGCTTGGGGACAAGGAAAAATTAATTTAACTCGG
+GATTTTCATTAAAAAATTAGGTTTTTAGTTAATTTTTCGATGTTTTCACT
+GCGAAAAAGTGTTAAAATAACGATTTTTCAACCTATTTTCAATTAATCCG
+TGCAAAAAATCGTGTATTTCTCGAGTTTTGAAAGAAATTTATGAAAATCG
+GCATTTTTAATAATGGTTTTTCAAATAAAAATATAATTTTTCGGTGCAGA
+AAAGTCGTTGCTCGTACAGTTTTTTTAAAGCATTTTCACATCAAAATCCT
+CCATTTTTCCAGTAAATCGATATGGAGTGCGACGAGACAAAGCTGAGCGA
+CGGCGCAAGCGGCTGGGTGCCGAGTATCCCGACAGATATCGATTCAAAAG
+ACACACCGTTGCTCGATATATCTTCTCAGGCGATTTGGGCGCTTTCCAGT
+TGTAAAAGCGGTAAATTTTCCGACTTTCAAGGGAGAAAAGTGTAGAAAAA
+TCGAAATTACTTCTTAAAAATCTCGTAAAAATCGAATTCTTTCAGGATTC
+GGCATCGACGAGCTCCTATCCGACAGTGTTGAGAAATATTGGCAAAGCGA
+TGGCCCGCAGCCGCACACGATTCTTCTAGAATTCCAGAAAAAGACCGACG
+TGGCTATGATGATGTTCTATTTGGATTTTAAAAACGACGAGTCTTATACA
+CCGTCAAAGTTAGCATTTTTGGCTTTTTCAAACGAAAAAATACAATGAAA
+CACTGAATATCTAGTTTTTTTCTCAATTTTTGCCTAAAAAACGGCGATTT
+TTCACTAGCTTTTCAATTAAAATTTGAACAAAAAGTTTTTTAAAGGAAAA
+ACATGAATTTCTAGCTTTTTCAGAGGTTTTCTATTAAAAAATAGAGATTT
+TTGTGATATCTGACTGAAAAATTACCAAACTGTCGATTTTTTTAAACTAT
+TTTTCACTTAAAATCTGCAATTTTTTTTTTCGAGGAAACATGTGAATTTC
+AAGCTTTTTCAGAGATTTTCTATGAAAAAGGTTCGTGCCGAGACCCATGT
+GCTTTTAAACTTCAGAATTTTCCCAATTTTGAAATTAAAAAGAGAATGAA
+AATTGATTTTCATGGAAAAATGCGTTTTTGGCCCAAAACCTCCAAAAAGT
+ACAAATATAGGTCGACTTTCAACTGTTTTAGATCAATTTTTTTGCAGAAT
+TCAAGTAAAAATGGGTTCATCTCACCAGGATATATTTTTCCGTCAAACAC
+AAACATTCAACGAGCCCCAGGGATGGACATTTATCGATTTACGCGACAAA
+AATGGGAAACCGAATCGCGTTTTTTGGCTTCAAGTACAAGTTATTCAGAA
+TCATCAAAATGGGAGAGATACTCATATAAGGTAGAGGAATTGAGAATTTC
+AGAACGAAAATTGCCGAAAAAATGAAATTTTAGCGAATTTGAGTCGGAAA
+TTTCGAAATTTGATTGATTTTAAGCAAATTTCCAACTAAAATCTTGAAAA
+TTTGATCTTTTTAGATAAATTTTTTTTTAATTTTGTGCTTTTCAAAAAAC
+CTCAAAAAACAATTAAAAATTGAAGTAAAATTAATTTTTCAACAATTTTT
+GAAAGGCCGAATTTTTGATTGAAAATTTTCACAATTTGTCCATTTTGTGG
+TGGGGCTTATTCCGAAAAATCGTTGTTTTTTTTTTCAAAAAAGTTATAAA
+AACTTTAAAATTGCCATGTAAAATATGTTTATTCTCAGACCTCGTAGGCA
+CGAAGCAGGCGTAGGTCGCCTCGCAATAAATTTGAAAATCTCAAGAAAAA
+TCAATAAATTTGTGATTAATCAAAAAAATTTAATTTCCTGGTCCCAGCAC
+GAATGCTATTTTTCGAAAAAAAAAAAGAGGCGAGCCTAATATAGACCACG
+CCCACAAAATGGGCAAAAGTTTGATTTTTCAAAAAATCGAAACAAAAATT
+TTTCCAATTTTGTGAGATTTTAAAATTTCCGGTTTTTGGAAAATCGAAAA
+AAAATTTCTCGTTTTTTAATTTTCAAAAAAAATTGTGCCTAAAATTCAAA
+AAAAAAATCAATACTTTCTCAAAATTTCCAGAAAACAGTCCATTTTCCAG
+GCACGTTCGAGTCCTTGGACCCCAGCGATCTCGTGTCTCCACAACGAATC
+GAATATTCACCGGAGAACCACACGGACCGATTCCCGATAAAAATATCACT
+AATTTCGACGACGAGGATTTTGCCAATTTTATCGATCACTCACTTGTTCA
+CTTATCACTTCGTTAAATTTACCTCCAGTGATTCCAGATAATGAGCCAGT
+TTTGCATTGAAATTTAGTGCCAAAATATAGAAAATCGCATGATTTAACAT
+AAAATAGCGTTTCGAATTGAAACAATGGAAAAAAAGTGCTATGATGATTT
+TTTAACACTTTTAATTGTTCCAATTTGAAGTAAAATCTATTTTCAGATAA
+ATCAACTGATTTTCTATATTCTGCCACTAAAGCTTAAAAACTTGCCCTGC
+TGTCCTAACCTTCAAATTGTTCCCTGCAAATTTTATTATTCTTGTTTCAT
+ATTTTTGCGATTGCTTCGCGAGACCCAAACTCACACATTTACCTGTAAAA
+TATAATCGAATAATTATTTATATATTTTCTGTAAATTTCCTTAGTATACT
+ATAAATTTTCTGATCTCTCTTCAAAAATCGCTAGAAAAAATAAACAAATG
+TCGGTTTAAAAATTCCTGGTAATTTACCTTCTATAGAAAATTTTTCGAAA
+AAAAAACCGAAGAAATTCAGATGGAAATTCCCGATCCCGAACTGCCGGGA
+ATACCGATTGATCCGCAAGATTTGGAGATTCTAGACACGCCCACACGGTT
+TTACGAGAAGCTTTTAGTGCGTTTTTCGTGTCGGGACCCGGAAATTTGAC
+ATTTTTGGCGCGCGGCTTGTTAGACTCCAAACCTTTTCAAAGATTTTTTT
+TTCGAATTAAATAACATTCGTGCTTGGGCCCGGAAATTGAATTTTTGATT
+TGAAAACAATTTTTTTTGAGTCCAAAATTTTCAAAGTTTGTCCATTTTTG
+GCGCGTGGCCTAGTAGGATCCGCCCCTTCTAAATTTTTTTTGAGCAAGTT
+TTCTGAAGCATTGATTTCAAAAATTTTTTTTGGAAATTTCTGGTTTATTT
+TTCCGGTTTTTTTCCGAGTTGCTGTTTAAGTTTGGAGAAATTCCAGAATT
+TGTCAATTTTTGGGGCGTGGCTTTTTCAGTAAGCACAGTTTTTTTTTTTT
+GAAAAATTGAAATTTTCGCGGTGCGGTTCAAGAAAAACCACAAAAACTCA
+ATGATTTTTTAACGAAAATTTCAAATTTCTTGCAAGACCTACTGCAATTT
+CGATTTTTAGAAACTTTTTGAAAAAAATCCGAATTTTCTGATTTAGCCCC
+GCCCCAAAAATGGAAAGATTTCCGAAAATTCGAACCAAAAGTTCGCAAAA
+ACTTGAATTTCTCTCACACAGATTGACGCGCTAATTTGAATTTTTCCAAA
+AATAAGCCCCGCCCCAAAAATGGACAAATTTTAAAAATTTTGAACCAAAT
+AAATTCAATTTTTTTTCGCTTTTTTCCGTTTTCGAACAAAAAATTCTAAA
+AATATATGGTTCTAGGCGGGGCTCAGGCACCCATCTACCTACTTAAAAAT
+GCGTTAAATTTCAGGAATTAACTGCATCAACCGAACGGCGTCTCGCATTG
+TGTAGTCTGTATTTGGGCGAAGGAGATCTCGAAAAAAATCTGATCGCTGC
+GATCCGAGAAAGATCCGAAAAATCCGAGATTGAAGTGACGATTCTGTTGG
+ATTTTTTGCGCGGAACACGGACCAATTCAAGCGGCGAAAGTAGTGTAACA
+GTGCTGAAACCTATTTCGGAAAAGTCAAAAGTTGGTTTTTTTTGCAAAAA
+AAAATCGATAAATCGATAAAAACCGACAATTTTGAGAATTTTCATTTCAA
+ATTTGAGTCCCACATGCGCCTTTAAATATGGTGTACTGTAGTTTTAGCTC
+GAATGTTGAATTTCAAAAATTGAGAATAAAGAAATGTCGTGACGAGACCC
+ACAAATGTTTTGAAAAAAATTTTCAATTTCAAAAAAATGTAAAAAATTGG
+GAATTTCCCTCCAAAAGTTAAATTGGTTTAGTCACAAACTTTGAAATTTT
+GAAATAAAATTTTTTTCGGCTAAAAATAAGTATTTTTTAAAAACTATTTT
+GAAGAAAAAAAGTTAGGTCTCGCCACGATGTATCTTGTATATGTGTATCT
+AAATTGCCATGTCGTGACGAGACCCTCTCATATTTTACACTGCAACTTTT
+TCCTCACGAGGGACGAGGAAAAGTGGTTTCTAGGCCATGGCCGAGGGGCC
+GACAAGTTTCATCGGCCATTTATCTTGCTTTGTTTTCCGCCTGTTTTCTT
+TCGTTTTTCACAGCTTTTTCCCATTTTTTCTTATTAAAACTGATAAATAA
+ATATTTTTGCAGATGCCAAAACGATTTTCAAGTAAAAAAATCATGTATTC
+AGTGGGCAAGCAGCGGTGAAAGTGGGCATTGTAATATGATGGATTACGGG
+AATACAAAACCTAAACTTTTTCTGAAACATGATACATATGATGCTTAAAT
+GCTGAGACTACCTGATTTTCATAACGAGACCGCTGAAAAAGTTTTGAGGT
+TTTCAAAATTCAACTTTTTGTGCGAAAATCTCGACTTTTTCACCGAAAAA
+GTTGAATTTTGGAAACCTCAAAACTTTTTCAGCGGTCTTGATATGAAAAT
+CAGGTAGCTTCAGCATCTAAGCAGCATATGTATCATGTTAAAGAAAAAGT
+TTAGGTTTTGTATTCCTGTAATCCATCATATTACATTGCCCACTTTCACC
+GCTGCTTGCCCACTGAATACATAATTTTTTCACTTGGAAATTGTTTTAGC
+ATCTGCAAAAAATATTTATTTATCAGTTTTATTAAGAAAAAACGAAAAAA
+ATCAGTGAAAAACGAAAGAAGACAGGCGGAAAACAATACAAGATAAATGG
+CCGCTGAAACTTATCGGCCCCTCGGCCATGGCCTAGAAATCACTTTTCCT
+CGTCCCTCGTGAGGAAAAAGTTGCAGTGATTTTGCTCAAATAAAAAAATC
+CCCCAAAAACCGATAATTTCACCATTTATCAGATATATCTCTTCCACACA
+CCGGAGCTTAGTGGCTTAGTAAAACGAGTTCTTCCACAGCGAGCCGACGA
+GATTATCGGTCTCCAGCACATGAAATTATACATTTTTGATGACAATGTAT
+TGATTAGTGGGTTAGTTTTTTGTTTGCATGGGTCAGACTACAAACTACAA
+AAAGCCTAATTTCAGAGCAAATTTGTCGGATTCTTATTTTACTAATCGAA
+CGGATCGATATTTTCTATTCAGAAATTGCAAACCATTGGCAGATTTCTTC
+CACGAAATTATCAATGTTGTTGGTGAGTTGGCGATTGCGCTCCACCGCAC
+ACACTGTTCAATGGGGCTCGCTTGAACTGATAATTTTTTCTAAAAAATTA
+CAAAAATTGTTTTAATTTGCCTTCAAAAAACCATCAGTTAATTAAAATTT
+TCTAAGCAAAAAATTATATACTTTCTAAAAAAATTGAATTTCCCGCGAAA
+ATAATTTTTTCTGAGAAAATTTGAATTTTTCACCAAAATATTTTTTTCAA
+CATTTTTTACCACAAAATGAGGCGGGGCCTCGGTATACACGCTCAAAAAA
+TCAAAAAATACTTGTAAATTTGACTACCAGCTATTTTTTTTTCGAAAAAA
+AAATCGAAAAGTAGGCCAGTTTTCGAAAAATTCTCGACAAAAATTCCGAA
+AAATGGGGCGGAGACCTGTGCGGTATTCGGCATTCGGCATATGCCGATGC
+CGGTTTTTGGAGCCCGTCATATGCCGTTATGCCGATTTGAAAATTCACGG
+CATATGCCGAAAATGCCGTTATGCCGAAAAATCCCGAATGCCGCACAAGT
+CTGGGCGGGACTTCAAAAACCACGCCCACAACAGAGAACAAAAATTTGGA
+GTGATGGTTTGCAATTCCCTCGCGCACTTTTTCTTGTTTTTTTTCAAAAA
+GATGAAAAAGCGCTCTACTGTACACGTTTTTTTTCGAATATTTTCATTAA
+AAATCCAATTTTCAGCCGACTCGAGCTTCATTGTCGAAAATGAGCAACTG
+GTGCCGAGCCCAAAATGTGATGTGCACCCATATTTAGGTAATCTGAAAGG
+ATGGGTAACCTGAAATTTTTCCAAAAAAATTTTTTTTAAGGCTCCGCTCA
+TCTCTACCGAGAAATGCTCAAAACACGTGTGAATCGAGTTATCGAAAAAT
+ACAAAGAATCGCGAAAAACGTCGTCGAATTGCATGTCTGCTGACACGTGG
+ATTTACCCCGTTTTACAAATGGGGCTTTTGGGAATTCATCAGGAGTTTGA
+ATTTTTGCAAAAACTTTTCTCACTGAAAAATCCGGAGCTCAAAATGACGA
+TGGCTTCGGGATATTTCAATTTTATTCGAGATTATGAGGAATCGATTCTG
+AAAGAAGGAGATTATCATTTGGATATTCTTACAGCTTCTCCTTTTGTAAG
+ATTTTTTTTGAGGGAAAAATATCTGAAATAAGTTCAAAAATTTCAAAATT
+GAATTTTTTCGAAATTTTTGTAGGAAATTTTGGTTAAAAAAAGTTTTCTC
+GAGAAATTTGAATTTCCCGCCAAATTTTTTCTGTGAAAATTTGATTTTCC
+CCTCAAACATGTTTTCTCATAAAATTTGAATTTCCCGTCAAAATGTTTCT
+GAGGAAGTTTGATTTTCTCATCAAAATTTTTCAAAATTTCCAGGCGAACG
+GATTCTTCGAATCAAATGGCTTCTCGAAATATATTCCACCACTATATTCC
+AACATTTCTGATCAATTTCTTCGAAAACGAGAAATCAACGGCCGATTGAA
+TGTAAAAATGTTCGAATATCGAAGAGAAGAATGGACATTTCATGCAAAAG
+GTCTTTGGGCAGAACATAATAATCAATTAATGACATTAATTGGCTCATCA
+AATTACGGTTATCGATCGGTTCATCGAGATCTTGAAGCTCAAGTGATGGT
+TGTTACAAGAAATCCGACACTTATCGATCGATTGAAAGATGAGAAAAATC
+TATTATTCGAATATTCATCGATACTTGACATGGCTGCACTTCAACAACCG
+GAACATCATATTCCACCATTAGTTCGAGTTATTTCACGTCTTATTCGGAG
+TTTTTTGTAGACGTTTTCCAATTTTTTATAGCGGAATAATAAGGTTTTTG
+ACTTTAATAAATCTTTGTAGATTTCAGTTTTTTTGAAATGCAACATTTTG
+CCGAATTAGGCCATTTGACAATTTTTGGTCGTGTCACGGCGCGGTTTGCA
+GTAGAAAACTAAATGTATTTTGATTTGTTTTTTCGAAATATCCGAAAAAC
+AACAAAAAAATCTGTTTTTTGTTGAAAAAAATGTTGCGAATTTCAGAAAA
+CGGCACTTTTCCGATTTCTGCCCCCTAGGGCTGTTATGAGGGACGTCCCC
+TATTGGGGGGCGGGGACGATCATTTGTCCCCCCATGGGGGACGGGGGCTC
+GTCCCCGTCCCCACGTCGGGGGACGGGGAGCGCCCCTTGTCCCCGATGGA
+ACGAAAAGTCGTCCCCTTTTAATTTTTGATTTATTTTAGATTTTCACTTC
+ATTTATTACCGGTACAGAGAGTGTAGATAGTTAGAGAGTGCCAGACATCC
+GGGACCCAATGGAGCGGGGCGCGCGGAAGAGACGATTAGTGTCGATTTAC
+GAAATTTTCCTCGTTGTCATCATTTCGTAAATCGACACAAATCGTCTCTT
+CCGCTTGGGTCCCGGATGTCTGGCACTCTAACTATCTACACTCTCTGTAC
+CGATAATAAAATATTTTTACGTGAATCTCGTTTCCACTAAGATGTGCGGG
+TGGATACCGTGGATATTCCACACAAAAAACGTGTCGCTTTAATAATTATG
+AAGCAAAATACAAACGCACATTCTTCACATTGGGTAAAGGGGGCGCGCTC
+CCCCTTTACCCGGGCGCCCCTTTTCGGGGGGGGGGGGGGGGCGTATTACG
+GGAGGTTTTTTGAAAAATAATTTTTGAAATTTGTCAACTGTCGACAGCTG
+TCGTTCAATTAATGTTTTTTTTTCAAATCTCCATACAAAAATGTTCATAG
+TAAATTCTTTATCAATATTGGGGTCCCTCACAAAGTTCAAGTTTTCTTCT
+CACTCTTCACGGCCGCCTTCGATTTTTTCTTAAGACCTTCATTTGCATCA
+AAATACATTCGACAAATTTGAGTCACATAAGCATCATCATGTGCGTTTGC
+CTGCAAATGTTAACAAAGTACCAGGCGGATGCCAAGCTTTCACGTCTTCA
+TGTCTACGTAGAAAATGCAGTCATGAAGTAGGCACGCAGACAGACAGGCA
+AGTACATAATCAGGCAATAAATGGGCAAGTAGGCAAAGCAGGCATGAAAT
+AGGCGCTTAGGCACGTGGGTAGGCAGGTATGAGACATAGGCAAACATGCA
+GGCAGGTATGAAAAGCGAGAAAAGGCAGGTGAGCATGATGAAGGCACATA
+GGCAGGTAGGCAAGGAAGCTCCTAGACAGGTACAAAATAGATGTGCGCAA
+AGTAGGCATGTGCAAAGAAACTAAGCTCGTCGCCAGGCATGAGGTAAGCG
+CATAGGCTTGCAAGTAGGCGAGTAAACACGCGGGCATCGAATAGGCAATT
+AGGCAGGTATTTTTGTGCTCCATTTGGAAACACACTTACTGGATAGAAAA
+GAGTGAGAGTCGTGTAAAATGCAAATGCCAAATAAATTGGATCCGGTGCA
+GCACATTTTCTCTTTGATCTCGTTTGTTCAATCAGACTCCGATAATTGAT
+TTCTCCAGTTTCACTTGTATTGATCGCTTGGAAGAGGCTCTCGATGACTG
+AAAAATGCTCAGAAATTTCGGATATGTTCTCGATTTTCAGTGAATTTTTC
+CTGAGAAAAAGCTAAAAACTCACGAACAAACGCTGCCGATCGTCCACCAC
+CAGTATTGCATACGACAAAAACCGGTCTCTCGCTGTCTGTCACTAGTTTC
+AACAAATACCTAATCTCCTCGGCATCTTTCGGTCCCATATGCTCCGGCCA
+TCCGGTATACTGGTAATGAGTCACCTCTTGAGTACGCTTCTTTCTGGAAA
+AAAGTTTGTTGCAGGCTACCTTTTATGCCTGCATGGAAAAAAATAGTAGG
+CGGACAGGCGTGAGGAAGGTTAGAATATTGATGAGAAAAATTGAAAACAA
+TCATTTCAAAAAGCAAAGAATTGACCGGTTATTATTAAAAAATAAAAATT
+TTTATCCGGACAATCCGATGCAGATGTGAGTGCCTGCCTACCGGCGTGCC
+ACCGCGCCTATTTCATGCCTGCGTGCCTATACTTACCCAAATGTTAGCAA
+CAATTGTCTAGTCTTCAACAAAGGCTTCGAGATACTCTTCGTGCAAGTGA
+TTGTTAAGTCCGCCAAAATTAGTTTTTCGTCGAGTTCAGTGGGAAAGTAC
+CTATCACAGTTCACCTTATTAGCTCCAATAAAGTGATCTGAAAAATAAAT
+GGATTAAAAACGGAGGGTGGCTTGATAGACAGGCAGGCAGGACTACTGCC
+CTGTGTAGGCCGTCTTGTAGACAAGCAGACAGGAGTGGGTCACCATGTAG
+GCAGACGGGAGGGTGTAGGTTGTCTAGTGGGCAGGCAGGCGTAGGCTGCT
+GCCAAGCAGATATAGGCTCACCTATTTCCGCGAAATCGCACAACATCACA
+ATTGTGCTTGGTTTATTCAGCTTCACTGACTCCCAAAATGCGGCAATCGC
+CAAAATATCGGAGCTTTTCTTATCAACAGGCAACTGCGGAGCAGGCATCA
+ACACAAACTTCAAGCCGTTATCCAATTCAACAACATGTGATGATTCTCCC
+TGGCTGAAAATGAAGATTTTTTGGTAGGTACCCATAATTTTGCCTACCTG
+TCTACCTATGTGCGCTTGAGTTAAAGGTTAAACCTAAGCCTATGCCTAAA
+CCTGAGCCTAAGCTGAAGCCTAAGCTTAAGGTTAAGTGTAAGCGTAAGCG
+TAAACCTAAGCAATATGTAGAGGCGAAAGGTAGGCAGGCAGGCGTAACAG
+TCTTACCCATTCTTTTTCGAAGACTCATATGACACCGGATCACATTGACA
+GTGATTACCTCCCTGTAAGCCGCAAAACTGGGCAAAATCGTCTCCCGTAA
+TTTCTAGGTTATTTGGAACATTCTCAAATACTGAAGTACAATTTCTTTTT
+CTAGTAACGAAATCCGAAATTTGCGTGTTGAATGTCTTGAGGAAGTTTGA
+AAAACGTGTCTCATTCACATCCACACGACTGATCATCTGATTTGGCGGGT
+ACAGTTTCTCTTTTTCTTCCGAGTCGAGTATTTTGTAGCCGTTCGGGGTT
+AAGCAAAAGTAAGCAATTATTGCACAAATTATGACAATGACGATCAGAGC
+CAAAATTACATATTGTCCGTGTGTTCTGGGATTTTGGAAATTTTTAGTGA
+AGCTTCTAGGCTTTAGCTTATGCTTAGGCATAGGCTTAGGCTTCGGCTTA
+GGATTAGGCCTAAACACAGGAGCATATAGGTTGGCAGGCAGGCAAAATTA
+GAGGTACCCGCCAAATATCTAGAAGCTTCACTAAAAAAAAAACGTTTTGA
+ATTTAGCATGAAAACAATTTTGAAAAAGTAAAATGTTTTCTTATCTCAAT
+TTTTTCCTTGATTTTATATTGTAATTAAAAATAATAATTTGAATTTTCAG
+CTCGATTTAGATAGAGTTGTGCTAGATTTCAAGAAGAAATTGAGAATTTT
+CGTAAAAAATATTTTTAACGCGAAAAAATTTTTAAAGCTTTAATCCAAAT
+TGTTCAAAAAAGTTTGGAGTAAAAAATTTGGAATTTTTTTGATTTTCACC
+CGAAAACCTTTCTTTAGAATGTCTGCCTCTTGCCTCCATCCGCGCCTTAT
+GCTCAATCCGCGCCTTATGATTTTTCTCCGGGAACTTGAGACGATTTGGT
+TGTTGGGAGAAGAAGTGCGGAATGTGGAGCGTTTGTTGAGAAAAGATAAA
+ATTTGGAATTTTTTTGATTTTCACCCGAAAACCTTTCTTTAGAATGTCTG
+CCTCTTGCCTCAATCCGCCTTATGATTTTTCTCCGGGAACTTGAGACGAT
+TTGGTTGTTGGGAGAAGAAGTGCGGAATGTGGAGCGTTTGTTGAGAAAAG
+ATAGATTTTCTACTATTTCTCAATTATTCAATACTATCGAACGACTTGAT
+GTCCAGTCTTTGAATGTTCTTGTCGAGGAGGCGAAGGTTATTGGTAAGTG
+TATGCGTGGCTTTCCGATGAATTACCAACGGCACGGAAAGCCTGAGTGTA
+CCCTTTCGATTTCATCTTCGGAAAGTGTGCTAAGCGTAGGCGCGTTAAGC
+TAATTTTTCCTGGTAAATCCGCAATTCTTGAAGATCGAACCAATAGGGAA
+CACTGTGGCACCACGTGCAACTTCAGGGGTAGGCGGCAAACACAACGGAA
+ATTTATCGATTTGCCCAATTTGCCAGAAATTTCGGTTTCCGAAATTTTGT
+CGATGCATTAAGGGTTTGATAATAAAATCGAGTTTGGGAATTAGCGTTTT
+TCAAAAATTGTCGAATACCTTCAGAATTTTGGTTTCCGAAAGTTTGTCTA
+AAAATGCAGGGGTAGGCGGCAACTGCCGTTTGGCATATTTATTTTTGGCG
+AATTCACCAAATTCCCGTGAAACATGCGTGAACTTTCTTCTCGTTTCTTA
+ATTAGTTTTTCATCAAATTGATAAAAATGAGAAAATTATAAATTTGTAAA
+TTCACTTCAAAATGCAGGCGGGCAGGTTTCAGTCAAGCCCTGAAACCGCG
+CCTGTCTACCATGGAAGCCCTACTTTCAAATAAGATCAACTCACTGTGGT
+GGTGGACCATTCTTTTCAGAATTTCCAAGATCTGGCGGTGGGAGAATTGC
+AGTCGGCAGAGGCTTGAATAAATTTGAAAAAAACAAGTCAAGAGCAGCAA
+GAGCCTTTTTCGGTTCATCAAGTCTGTTTTGAAAACTTGAAAACTCCAGT
+CCACCATCATCCAAGCTCTTCAGAGCATCCTGAACTTCACCGAGCGACTT
+CTTATTGCCAACATCCTTCACAAGTTCTACCAGTTTTTCCAACGATTTTT
+CCAAGCCCATAAGACCACCAAGATTAGCCCAATCAACCTTCTTAGCTTCC
+GTGAAAACATAACCATAGTCTACAAATTTTGTGGAATCAGACTTTTTAAT
+TCCACTCTTCCATGCATCTAGCTGAACAAACATCACATCCAAAGATGCTC
+CAAGCGCCACCAGCTTCTCCAGATTATCCTTATCGTCCTGTGCCAAAGTG
+GCTCCACTCGCTGCCAACTCTCGTTGCACAATTTGTGCATGGTTCTTGAT
+AATATCCACATTTGCTCTTTCTCGGAGCACGTCCTCCAGTCGAGCAATTT
+CTTGTGCCGCTGGGCCAATGGAATTAGTGTGTTCAGCGGCGTTTGGAAAC
+TGGGATGTTTTATCCGAAGCAAATTTGCGGCGCTTGCTAAAGTACAGCGC
+CAGAGATTTCAGACCACTATTGAGGCTTGAAACTGAGATCAGAGCATCTT
+CGACGGCAGTGACTATCGGCGGGAATTTTTGATCTGCTCGGAACGAATTC
+AAATCTGACAGGTTCTTTTGAATTTTGTCCAATTCTTTGTTGGATTGAAG
+ACAGCTCAGTACGTCGAGAAATTGAGCAATATCAGATCGAGAGTCATTGA
+TTTTTTCAATAGCACGTTTTTCTAGTGTTTTCAAAAGATTCGGATTCAAG
+AAAGTAGCGTTTGCCGTCATTCTACTCATGGTCAGCGACAAGCCGGTCAT
+TTTTTTCACTCCATTAAAGCATGGCTCAGCGGTTGTCCAATTGCTATTGT
+TCATATCCTTGCAAACAGTGAGCACTTCTGCGTGTCCTGATTTGCTTTCA
+ACAAGTTGATTCATCACACTTTTCAATATCGATTTCGATTGTTCCAATTC
+GGTGTCAATGTTCGATGCAATTTTAGATAGTTCCTCCAGATTCGTGAAGT
+CGGGGGCGGTAGTTAGAGTAGATTTGGCGCATTGGGCTGAAAGTTTATTT
+TTATTTTCGTTTTTTTGAGTTTGAACTTTTGTGGACAACCGACAGATTGG
+CTCAAACTAAAAGGACTCTAAAATATACAAATTTTGGAACTCAAATCAAT
+TTCGCAAATATTACTTTTTTCTACGGAGCTTTGATCAGGGTGGGGTGGCA
+AACGATTTTTTTCCAGCAAACGGTAAATCGGCAAACCGGCATTTTGCCGA
+TTTTCCAAAATGGCCGAAAATTTTTGAATCCCTCCCTCTAAACACTTCCG
+GCAAATTGTTATCCAGCAAACTACAATTCGGCAAATTGCCTGAATTAAAA
+ATTTCCGCCCAATCGGCAAATTGCAGTAACTGCAAATTTCCGATAAATTT
+GGAGAAACCGGCAAATCGCCGAAAATTTTTGGTAACTGGAAAAAATTTCA
+AAAGGCACTGTACCCGTGCTTCCGTTTTTTAAAAAATGCTTCTAAACAGT
+TCCGGCATATTGATATCCGGCAAACGGCAAATCAGCAGTTTGGCTAAAAT
+AAAAATATCCGGCGAATCAGCAAATTGCTGGAATTAAAAAGTTCCTCCAA
+ATCGGCAAAACCGGGAATTTGGTGAATTCGCCAAAAATAAATATGCCAAA
+CGGCAGTTGCCGCCTACCCCTGCATTTTTAGACAAACTTTCGGAAACCAA
+AATTCTGAAGGTATTCGACAATTTTTGAAAAACGCTAATTCCCAAACTCG
+ATTTTATTATCAAACACTTAATGCATCGACAAAATTTCGGAAACCGAAAT
+TTCTGGCAAATTGGGCAAATCGATAAATTTCCGTTGTGTTTGCCGCCTAC
+CCCTGAAGTTGCACGTGGTGCCACAGTGTTCCCTATTGGTTCGATCTTCA
+AGAATTGCGGATTTACCAGGAAAAATTAGCTTAACGCGCCTACGCTTAGC
+ACACTTTCCGAAGATGAAATCGAAAGGGTACACTCAGGCTTTCCGTGCCG
+TTGGTAATTCATCGGAAAGCCACGCATACACTTACCAATAACCTTCGCCT
+CATCGACAAGAACATTCAAAGACTGGATATCAAGTCGTTCGATAGTATTG
+AATAATTGAGAAATAGTAGAAAATCTATCTTTTCTCAACAAACGCTCCAC
+ATTCCGCACTTCTTCTCCCAACAACCAAATCGTCTCAAGTTCCCGGAGAA
+AAATCATGTGATCAGTAGTTTCTCGGGCCCAAGCGTCGGTTGCCAATTGA
+GAGTTTAGTGCTCCAATATCAATTGCTCCATTCGGTAGACCAACTGTGTA
+CTTCTTGGTTCGCAGGGACTGCCCGATGGATTCGATGGTTTGAAGATGGA
+TCTTCGATTCTTGATTTGGAAATGCATTCCGGATAGATGCCATGTGTTCT
+TCTAGCTTTCTTAGTCCCCGATTGATGTCTACAATCTTGAAGGATGAAAT
+AAAGTTCATCACATCACGAACTTTTGGCCATAATACAAAGAAAGAAGCAG
+CAGAATTATTGTTTTTGAAGCCATGCAACGTAATCTTCGGATTCTCCACT
+ATGTTCAAAAAATCTTGGGATTTTTTCAACAAATCGTTTAACGCAGAATG
+GGATTTGGGAATATCGGTGAAACTAGTGAACGCTTCAATCTCTGTGTACG
+AGTTGCTCCATACTGATAGCTTTTCGGAAAGGGTTGTAACTGATGAAAAA
+CTGTCTGTAATGTCTTTCATGTCTGCCTTGAAATTAGTCTCGTCTGGCCA
+CTTCTTGAGATCTCCAATATCATGAGCCACGTGGACAACACTTTTGACAG
+TTGTGAAGAATTGATCTGCCTCAACATCGTCGCCGATATTCGATTGTAGT
+TCTATAAAGGTATAGTTTTTGGGGGCAAAAAACGAAAGTGGTTCAAAATT
+TTGGAACAAAATGCCTATTTTTAGATAGCTAAAATCTAAAATTTTGCAAT
+GCTGACAAGTTGTGAAAATTTGAAATTTTAACAGAAAATAGGCTTTTTCC
+TAAACTTTGAATCACCTTACTTTTTTTTTGAAATTTTCGAAACTTTTCGG
+TTATTTCCAAAAAAAAGCCGCAAATACTCTATCAGGGGTAGGCGGGAATT
+GCAGTTCGGCAAATGTATTTTCTGCAAATTCGGCAAATCGGGATGTGTAC
+AATTTTGTCGTCTCTGGCAGTTTACCGACTTGCCCATTTACCGAAAATTT
+TAATTCCGGCAAATTGTCCATACTCTATTACTACCATAGGCCCTTATATA
+ATCTTTTTCCGCCCACCCCTGTACTCTATTACCACCTAATCTGTTACTAC
+AGTGGATTTTTTGAAACCAAAATTTCAGCTTTTGAATTTTATATTCGTAG
+TGAAAAGATATTCGTAGTGAAAAGTTGAAACCTGGAAAACATAGTTGCAT
+AATTGCATCGTAATATGTAAAAATAGGTCTTCCATGGTAGATAGGCGCGG
+TTTCAGGGCCTGCCTGGAACCTGCCTGCCCTATGTGAACGAGTAGACTGT
+AGTTTTAAAAAACAAAAAAAGGTATTTGCCTAACAAAAAACATACTCAAA
+TATTTGAATGTTTGCAACCAAACCTTTAAGCGCTATCAGTTTAGATTCCA
+GCGAACTGTAGTCAATTGCATTCAGTTGATCCATTGAGAAATCGTATTTG
+AACAAATCCAAAGTTAAATTCATTGATGGAATGGTTCCTTTTGTCAATTC
+TTGTTGTAGGTACATTGCATTGATCAATCGTGAGGCGAATTGTAATCGCT
+CAACGGCAGTTATCAAGTTGTCATCTGCAACTTTTATGAATGATTTTTTT
+AAAAAGTTATTTGTTGTCATTTTTCTTTTATTAATTATTACGTATATTAT
+ACGTATCATGCGAGTTTAGCTTTCCAACCCCCCGCGAACTCTTTTTACTT
+TTTTTTTTTTTAACTTTTGTCTTTTTTGTCCTTTCTTGGCTATTTTTTTT
+ATGAGAATTGACCCGAATTTGACTTTTTTCGGATTTTTAGGAATTTCTAG
+GAATTTTTCTTTTTTGTCAAAGCGAGCTAACGCTCGCCACTGACGCCAAG
+CCTAACATAAGACTTAACCTAAGTCTTAGCCTAAGCCTTACAAGGAAAGT
+CTTTGAAGGGGCCTGTAGATTTGGGTTTCTCATGTTGATATTCCGATAGA
+AGAGTGTTAGTTTTGATCTCTCCAAAAAATTTAGCTGCCCAAGCCAAGTT
+TCAGCAAAGTAATGACATTTTGAAATTTCAGTTAAAAACACCATTGAAAT
+ACACTGTCTTACAGTGCTATCCACACAAATATCAGCTTGCGTGAACACCG
+AAAATGTGACGCCCACCACAATAGGCTGAAGACAGTGGATTTCAATGGTG
+TTTTTAACTGAAATTTCAAAATGTCATAACTTTGCTGAAACTTGACTTGG
+GCAGCTAAATTGTTTGGAGAGATCAAAACTAACACTCTTCTATCGGAATA
+TCAACATGAGAACCCCAAATCTACGGGCCGCTTTAAAGACTTCCCTTGTT
+AGCCTAAGCCTATGCAAGACACGCAAAATATACATTAACATATATATACA
+ACAAATACAACGTAAAAATTGTTTTTCTGTAATTCGACTGACAAACCTTT
+AGCTTCACGTTTGGAACGTGGATCTAATGACATCACATTAAAGAAACTGG
+ATTCTTCTGGAACAAAATATATTGAAATTAAAGCTCTGAAACAGTCAAGA
+AACCTTCGAAAGTATCCGAATTGACAACACGATTAACCGTTATAATTATC
+AAAACGATTATTATTTTGATTCCTGGAAGACAGAAGAAATTCGGAACGAA
+AATAAAAATCAACCTACTCATTGCAAAGTATTATGAAACTTCCCTTTGAT
+CGACGGTTTTTGAATCAATTAATGATTGGAAGTGTGAATTCTGAGAGAAG
+GAGTGTTGGAATTTTTATTTATTTTATAACGAAAAGGTCACGGTTTCTGT
+AATTTTAATTTCTATGAAAGTTTTAGGGACTCACAGAATGTCAAACACTA
+GATGGCCGAAGAAAATTTGACATAAGCAGCGAAATTTGACCTTTCAAAAA
+AAAATTAATATTACGTGAAATCTTTTTTTTTCCAATGGAATTGAATTTTT
+GGCTGATACATGAGGGAATGTGTTTCAAGCTGTAATTTCAGTAAAACTGT
+ACAAGAAAAAACGTTCAATATTTTTACCTTTGCTTATAACTCCTCTACAA
+AATTTTTTCGGACAAAAAAATAAAACAAGCATGGAGATTACAGGTGAATT
+TCGAATCCTCATCTTCATTTTTCAGACTGAAAATCCAAGAAAAGTAGCCC
+GAACTTTTTTCTGAAAAAGTTCCTATATACTCATCAAACATTCATAAACA
+GTATTTAAACAAAAAATCCCGAGATAACACTTTTGTCTTCAAGATATTCA
+GGTTGAAAACTAATGTCCTGAAACTTGGATTTTGGGTCCTTAAGAAGATA
+AAACAGATAATTAGCTTTTACGTTAATACCCGCAATCATTTGCAAATTAG
+AGCAAAATTAAATTGAAACTTTTTTTTGGATTTAAACATTTTTTGGAGCC
+GAAATACAAGTTTCAGGACACTAGTTTTCAACCTGAATATCTTGAAGACA
+AAAGTGTTATCTTGGGATTTTTTGTTTAAATACTGTTTATGAATGTTTGA
+TGAGTATTTAGGAACTTTTTCAGAAAAAAGTTCGGGCTACTTTTCTCGGA
+ATTTCAGTCTGAAAATGTATGATTTTTTAATTCAAAATTTGAGGGAATGT
+CGTTCATTGTGGCTCGAGGTCAATGGATAAATGGCTAAGACTAAAACATC
+ATTGATCGAAGAATGATTTTTTATTCATAAAAACTATATATTTGACCTGA
+AATCATTGTTTTTTGTCACTATAACCCATTGGAATGAGCTGTAGAAATTA
+ATTAAATTTAGAAATGATTTTACCGATACGTGGCAATGTTTAATACATTA
+GTTTTCTGGCCGAAGATTTGTATGTTTTCCCGAGAAAGTGAAGCGACAGC
+TTAAAAGCGCATCGCCTTTAGTGAGAGGCAGGTCTCGACGCGACGACATC
+TTTCCTCGCGCGCAGCGGCGAGATTTCGTCATTCTACGTGTTGGTAAAGA
+AAAAGGACGTGATTTTATCGATTTGCATCGATTTTTTTTGGATTTTTCTT
+TGTTTTTATTGTATTTTTATCGAATTTTTAGTAGTTTTAAGGTTTTTTAT
+CGATTTTCCTTGATTCCGTTGCGTTTTTAAGCGTTTTTCTCGTTCGTAAT
+GATAAAAAGGGGGTTATTTCTCCGTTTTCCAAGAGTTATCTGCGCGTATG
+CCAGATTTTGCAGGAGGAATCATCAAAATTCTCAGTTTTTGGCATGTAAT
+CCTTACGAAGAGTACTTTCTGAGGCTCAATGGCTTTTTCCCCCGCTGTTA
+GGTGCTTCAGTAAGTGTTCTACTCCTTTCAGGGGTTCCTTCTCTCGTCTA
+GGAGATTAAATATGTTCGCATTTGTTTCTTCCCTCTCTCTTACGCGCTCT
+TTCCAGCATTGTTAGTTTATCCACGCTCTTTTCCTCTGTAATTTTTCGTT
+TATCACTTTCTCTAATTTTTCGGTTTCCGGTTCGTGCACTCGCGCACCCT
+CTCCCTATTTTACTCTATCTCTCACTATCTCTCACATCTATCTCTATCTC
+TCACAAGCTATTTTGGTATTTTGCGCGTTAAGAAGTCATGTTTTGATGGA
+CCGTGTCCAAAGGAAGAATATTTTCGTCGAGTGAAAGGTATGTAACTTCG
+TGTGAAGTCGACTCCATGAGTCTTGTGAATATTCCGATAACGTTTTATCG
+AGATGTATTATCGGGCGGCCCGAATTTTATGTATGTTTTTCATTGTGGTT
+ACCATGTAACGGGAGTTCACATCGCAGAAAGAGCAATTCTTTATCGCGAA
+AGTACGATTTCAGGCCCCGGAAGGCTTTCTTATCAGTTTAATGCGACATC
+TTTCGTCGGGTGAGATATATTGTCTTGCGTTTCTATCGCATTTCATTGGA
+CCGGTCGAGCCAGGTCTGAGTGTTTATGAGTACGAGTCGACTCCGTGAGT
+CTCAATGATTTTCCGTTTTCAGGCGGTTTTCAAGGTTTCCCGTTCTTGGT
+TTCTGCTTCATCTTCTACTACCGTTTTAAGTAGGATTGGCTCAAGTCTAC
+GGAAGAGTAGAGCAAGCCTACGAAGAAGGTCTTCGAAAGAGTAGCGCAAG
+TTTACGGAGGATTCACGCAGGTCTACGGAAGAGTGGAGCAGGTATACGTT
+AGAGTGGCACTAGACCATACTGGGAGTCCGATTTCCAATTGGATTCTCGA
+AAAACCTTGTACCTGCACAAATAACCAGACGAGCCGATATATCTACCTTA
+CCGAGCTCCGGGTTAATCGTCGTCAAGTATTTCAGGATGAAGCGTATAAG
+GCGATGATTTTCTTTAGCTATGCCGCGCGTTTTGCAATTGCATAGCTGTG
+TATTCCGTGTAGACTTTATCGCTCACTTGTTCGATTTTCAGGACATCCGG
+TTCGACCTTTTTTCTTTCTCCCGCTATCGACGACGCAGATCACGTATGAG
+TTGCTTTTATATACGGCGATCGATTGGTCCGGTATACGTAAAATTAGCTC
+TATATTTTATCGCTTTCGTTGCTCACGCGATTCCCAGGTATTTTAATGTC
+GAATCATATTCCGTCACCTACCACTACGTAGGAGATATGCAGGGCTATGT
+GAGAATAACTCAGGTTTCGTAAGAGTTTCTCAAGACTAGGGAGGATATTC
+GCAGGTTGTTGAGTAATTTGTTTTTCCAATTAGCTATTCTCCTTGTCAGG
+ACTTATTCAGGTGTGAGTCGAAGTAGCCCGAGACGTTTGGCCCTAGTATG
+GATACTTCACGACAGTTTCAGACAGATTGTGGTCCGCCTTTAATGGGAAT
+TATTTCTACTGCACAGGTTCATAGCTGACTTAGCCGAATGAGCCCCTTCG
+ACGTCGCAATTTGGCGGTTAGCACACTTCCAGGAAGACATAGACGAATCA
+CAGTTTCAGAATTCCTATACACTTCAGTAACTACGGAGTAAGGCGATCAG
+TTCCTTGCCGCATTTATATGTTCATCTTAACTTTATTTTATATTAGCTCA
+CGGCTTTCATTGGAAACTACAGATAACTGAGCCAAATGCTTCGCCTTTTT
+GTCACTTTTTCCCAGTTCACTCAAGCCCAGAGTAGATGTAGTTTGAGGTT
+ATCTACTTCTCGTTTCCATGTGCGGATACTAGCAGAGTTTCTCCTGTTAT
+AACTGAGAGTCATTTCACACACAATACGGTTTATCTGTCGGCAGTTTCTT
+CTCACAAGGTTTTCGCTATAGATGAATATCTGGTATAGGGGTGAAGAATC
+TGTAATTATTAAACGCCTCAAGCTTATAGCCGTGACTGACAGTTATAGCC
+CCCGGCTTTGCTGGTTCTACCCTATACCACACAAAACCCAAACCAATAAA
+CCCATAATACTATATAATTCGTGTTGTCTTATTAGAGCGTAACTTGATCA
+GGGAAAACGAATTCTCGGGGAGCGAAGCGATCCGAGAATTGTATGTTTTC
+CCGAGAAAGTGAAGCGACAGCTTAAAGGCGCATCGCCTTTAGTGAGAGGC
+AGGTCTCGACGCGACGACATCTTTCCTCGCGCGCAGCGGCGAGATTTCGT
+CATTCTACGTGTTGGTTTCCCCCCTCCCGCCCCACACACATATTATTCCA
+AAGTGCGAGACACATATGCTATGATTTCCCTTCCGGAGAAAAATCGAATT
+ATTATGAAAATATTAAGTTTAAACCGTAAGTCGTTTATTTTCAGGAGGTG
+AGTTTTATTTTTCCTTCATTGTCGCCTGAGTGGGCAGTCGGTGTCTATCT
+GCAACATTCGCAGCTCGACCCTTGTGCTTGTTTTGGCGGTAGCAGGAAAC
+TTATGGGTTTTTTCACAGTTTCGGGAGAGATATTTACAGGCTCTGGTTCA
+GGGAACCAGATTCAGAGTTTAATAATGATATATCTTTACAGGAAAATTGT
+GGTTAGAGTTTCATGGCAGCTTCAGATCCCCTGATGATCAACAGTTCAAT
+CCACGGAAACACGGACGAAATGAGTGGTCCACCGAGCAACAATGTGGAAC
+GAGACGATTCCAGGTTTTCCATGCCCCCTAACATCGATGATGGTCTTATG
+GTAAAGTTCTTCCAATCAAGCGGTGTTCGTGTTTTGGATAAACTTCTTCG
+ATAAGTAATACTTGACTAAAAAATATCGAGAATTAAAGTCACAATTAAAA
+TTTACAAAATATTTTGTTCCAGATTATGAATTTTCGAAGATTAGACTATT
+CACGGCCACGTAGCGTTTGACATGTTGTGGGACTGAATTTCTACAAAAAC
+GTGAACTCACGTAGACTGTCTCTTGAATAATTTGAATGAAACAGATGTGA
+GCTCCGGAATAGGCTTAGGCTTAGGCTTAGGCGGGGCTGGGAGGAGAAAA
+AAATTGCGGAATTTGCCGTTTGAAGAGCTCGGCGAGTTTGCCGAGTTTGG
+CAAATTTTAAATTTTGCCGTACACACTACAAATTGGACAAAAAATCGAAA
+TATCAAAAATAACAAATTGTTCTGAGTTTGATCAGTTCGGTAAGAAAATT
+TTGAAAAAAGTGATTTGCAGAATTTGCCAAGCTCGCCTTTGTCTTTGGTC
+AATTTAGCACCATATGAGTGATTATTATCAATTTTCCCACTGTCGCTACT
+TCACATTTAAAAAGTAGTCATCAATTGCCGAAACAACTTCCTTCCAGCTT
+AAACTTTTTTCTTAGCCTCATCGGGACCCTTTCCTAATCCCTTCTTAACC
+TCATTCTTCCCATCTTCCAAAATTTCCATCCTTCTTCTTCTTCTTCTTCC
+CACTACGACCATCTTTGTCGTATAGCACCTTTCTCGCGAGAGTGTGTGGA
+AACAATTTGCGAAAAACGGCTCCCGATCCCCCCATTCGTTTTGGCGAAAT
+CAATAGACACAAAAATGTTCAAACAAATCTCCCCTTCTCGTTTATCCCCC
+TGTTGCACAATATCCTTTTCTCACAAAAAAACCTTTGCTCTTCAATTTTC
+GGAATCATCTTTTTGCGCTTTGTCGTGTTACTGTGAAAGGCGGAGTACTG
+AAATATGGAAAATATTTTTAAATGACTCCCTGATTCCGAATATCTATGTG
+AGAAAGTTCAAAAAATTTTCCCTCATTTTATATTTCAGCTTGAAATCGTG
+ACTTTCATTGTGCACTAATGAGATTTCGATTTCGAAGTTTTTTTGAAATG
+TGTTTTCAAGGTCAATTTTCAAGGTCAATTTATTATTTTACTATCGAAAA
+ACTAAAAAAATTTCAATGAGTAAAGTAAGTAAGTAAGCATTTCGTAAATA
+TACAAAAATCTCGTAAATCGACACATAGCGTCTCTGGCGCGAAAATTCGA
+AATCTCATGGGTGCACAAATGAAATGCGAGATTTCAAACTCAAATGTAAA
+ATAAGGGAAATTTTTTTGAATTTTGTCACATAGATATTCGGAATCAGGGG
+CAAATTTGAAGTCAATTAAAAATATTTTTCAGATTTCGTGGTACTCTAGT
+CTAAAACTAAAACTAAAACTAAACTAAAGTTAAATTAATATTAAATTACC
+ATGAATCTAATTTTTGTTTTTTAAAGTTTCCTGCAAAAATTCCAAGATCT
+CAGTTTGCCGAAGTCTAAATAACGACAACTCTGAACTTTTGTCCCGAAAG
+AAATCGAACACCGGTGTATACTAATAAGATCCCTCGAAGCTCGGTATACA
+AAAGGATCATGAAAAAGGGGTGTCTCACCTTGCGCATAATACCTTCTGTC
+TTTCCCCCTTCACCAGAAAGATTTCCTTCTTATATTTGTTCGTTTCGTTC
+CTGCACACTCTCCATCTCTTCTAACCCCCTCCTCATTCAGAATACTCTCT
+CATCTCACAACGCTTCTGTCTACCTGCCTGCGTCTCCTCGGTACCATATA
+CTATCTTGTAGCTGCCACTTACCAACAGACTTGCCTCTTGGAGGTCTCTC
+TCTCTTTTCCACCAAATCACCTTGTTCTTCCGACTTGTTCTCTCTTATCG
+AACTGACTTTTCGTGTCTGCGGGCCTTTCACATTATTTTCCAATTTTATT
+CGAATTTTATGTGCCCACTGCTTGCTAGGTTTATTGAGTGCCGCATTAAT
+TTTATTGATTAAAAAAAAAGCCACTTGTAACAATTTTTATGAAATTTGTT
+TGCATATTTATTTAACAGTAGCGAAATTGTTTTAAAATTCGTACTGTGTG
+AGAAATTTGCACTTTCGAAGTGTTTAAAACATTCTATTACGGGATCACAA
+GATTATGAGAATGCTTATTGCGCAACATTTTTGACGCGCAAAATATCTAG
+TAGCGAAAACTACAGTAATTCTTCAAATGACTACTGTAGCGCTTGTGTCG
+ATACTGGCTCGATTTTTTAAATGATTTTTTTTCGAATAGTGACGTCGATA
+TTCCATTTTGCTTTCTTTTTCGTATTATAATTTTATTCATTTCGAGAATC
+GAGCCCATAAATCGACACAAACACTACAGTAGTCATTTAAAGAATTACTG
+TTATTTTCGCTACGAGATATTTAGCGCGTCAAGATTTTTCCTTACGGAAA
+TACAAACTTCTTGGCGAAAATTTCACGAAAATTCAAATTTCCCGCTTAGA
+ATTTCCCGAATTTTTCGAATTTCCTGCCAAATAAAAACTAGTTTAAATAT
+TTAAAAAAAAGCTTAGAATTCTTAGAATGCGTATTGCGCAGCATATTTGA
+CGCCCAAAGTATCTCATAGCGAAAACACAGTAATTCTTGAAATGACTACT
+GTAGCGCTTTTGTCGATTTACGGGCTCGATTTTTGAAATAAATTTTTTAA
+AATCTTTTCGAATCAAGCCCGTGAATCGACACAAGCTCTACAGTAGTTAT
+TCAAAAAGTAGTTTTGGCTTCGATCGAGATATTTTGTGTGTCAAATATAT
+TCCCGTAAAACAAAATACCGTCTAAAGATATAAAATTTAACGCCTATTAC
+ACCCCAAAACCCGCCGGAAAATCCAGAAAAATTATATAAATTCGCAGTCA
+CTTCTCAAAAATAACCTGAATAGTTGACCGCGTAATTCGACCCGTTTCCC
+TACGACTGACCACACCCCGATTCTCTCGAATTACCCGCGACAAGCTTAAG
+CATCTTTCTTCATTCCCACACTTTTCGTAAACTTCTGAGAGACAAAACAA
+TAATATTTCTTTCTCAAATCAATAATGCCTATATTCTCCGCATCCCGTAG
+CCGATCCCATCACCGTAATTCTAGAAATCCCACGAAATTTTCCAATTTCT
+CTATTGAAAAGGTCTCTCTTTTATATTACCCAGGCGCAAAATTTCGTGCA
+AAAATACAATCGACGGTCTCGACGCGATAATTTTTGCTAAATTCCAAAAA
+TGTGTGCGCCTTTAAAGATTATTGTAAATAGCTTCAAACTTTCACCGATA
+TTTTTAAAAATTGATTTTTCTATGTTTTCCGTTTAATATATATTTATTTA
+TTTAAAAATTAAGTTGAAATTGAGAAATCGATGAAAATCGAAAATTACAT
+TACTCTTTAAAGGCGTACATGTCGTTTCGAGACCGGGTACAGTATTTTCG
+ACTGCGATTTTGGTTTTTAAAAAAACCTAACCAATAGAATTTCCAGCGCT
+CACACTCATTGGGTGGAAGCAGCAGCAGTCCGACGAGCTCTTTTTCGTCA
+AACGACGAATTCGACGATCGTCAGAACAAAAAGTGAGTCATCAGTTTTGT
+TTGAACAGCAGGTGTGAAATTTATTGTGAAATTTAAAATGGGAAATCCGA
+AAAAACACACCTTGTGTGATCTAAGATCCAAAAAAAATAGAACAATCGAT
+AATTTTCGGGTAATTTTAAAGTTATTTTTAGCGAAATAAACAATGCATTT
+TTGAGGGATTGGTTTTCAGTCATTTTCGATTAAAAAATTCAATGTTGAGC
+TGAAAATATCGATTTTTACCAGAAAATTGATAATTTTCGAGCTCAATACC
+ACAATTTTAATGTTTAAATCGCTTTGAAACCTCATAAAATCTCCCGCACC
+TCCAGTTTTTGTAGTTTTCCGCCTAAAATGTCGGAAATTCAACAGAATAC
+TCATTTTCCTAGCGAAATCTATTAGTTTATAATAAATTTGATCGTTTTCT
+GCTTAAAATTCCCTGAAACTTCTGAAAAAAAACCGATTAATCAGCTGAAA
+TTCGCTTAAAACTAATTTCGTGCCGGGACCACGGCCTTTTAAATCGGTAT
+GCGCTTTTAGTTTTGTACCGTATCTATTTTAGTTTTTAAAGTAAAAAATG
+AAATTTTCAGCAAGTTTTGGCGTCAAAGAAATGTATCGAACGCAGAAATT
+GAACGAATAATCGAGGATTTCATAGCGAATGGTATTTTAAGTGAGTTTTA
+TTCGATAAAATCGACGAAAAACCAGAAATAAACAGTTAATTTCCAGAAAT
+GAGCAACGGGAACAGCTACAATCACCATCACCAATTCCCGATGAGCATTC
+CAATATCGTGCTCGTCACACTCAATTCAATCACAATCACGAATGAACACT
+CTGAACGCGAATAGGGATCTCCTGTCTCCCGGCAACGACGTAATTGTCAC
+CAGAACCGTGTCACCGTCGTTTTATTCGCATGGAATGCCGGCCCGGGATA
+ATGTTTTTCGAAAAGACGATCATGTCAGGATATTGGGGAATACAACGGTA
+TGAAAATCTGCTTTTCATCGAAAAAAATTGGAATTTTCAGGACCCAGCGT
+GGTATCGAGCCCGTAATGCGAATCAGGAGGAGGGTCTGGTTCATGCAGAT
+TGTGTAGTGAGAATAAAGTTGGTTTTTCTGATCAATTTCTGTGAATAACC
+CCGATTCCCATGAAAATAGGATTTTCAGCAGAAACTCCAGGCAAATTGAG
+TTTTTGATGCGAATAATGGATTAAAAAAGATAAAAATCCATGAAAATTTA
+ATTTTTTACATCAAAAATCCATAAAAATCGGATTTTTGAGCGGATTAGAT
+TACTTTGCCGAAAATTCATTTAGAAAAAAACAATTCTTGCGCGCAATTGC
+GCAAAAAATTCAGAAAAATGAAACATAAAAGTTAAAAAAATTATTTTTAA
+ATATTTTTGAGCTGAAAATAAAAGAAAATTCGGATTTTGTGGCCAAAAAT
+TCAAGAATATTCCATGAAAATTAGTTTTTGTTTGCAAAAATCCGAACAAA
+AATTAATTCTTTTTTTCGCTAAAAATTGAGAAAATGGTTTTAACACAAAA
+ATCCACAAAAAATTGATTTTTAGGCCACAAAATCTATGAAAATTCTGATT
+TTCTGGAAAAAAATTAAGAAAATTCAAATTTTTTGTTCAAAAACTTTTTT
+CAAAAGCATTTCAAGAAAATTTGATTTTTCATCAAAAAAATTAATAAATT
+TTAGCGGGCAAGCCTACGACAATGGAATTGTAAGAATGAGAGCTAGCGGA
+TGTGACGTGGCTCCGGGAGCAGCTTCAACAACCTCCAGCACATCATCACA
+TCATTCAACTGCAGCAAACCATCAGCCATGGTTTCATTCAATGATTAGCA
+GAGAAAATACTGAAAAGTAATATTGAAAATGTTGGAAAAATCTGGAAAAA
+TGCGTCATTATCTCGGTTTTCAGTCGGTTTCCAGTTTTATGAAAAAAACG
+TCACTAAAAACGACATATTTCTTTAAAAACGTAAACATCGGAAATTGTTT
+GCATGAAAAATGTCGCGATTTTCTAGAAAATTTTAAAATTTAAAGAAAAA
+TGTTGAAAATAGATTTTTTCTGAATTTTTTGAATTTTATTAGAAAATAGA
+GAAAACATCATGTTTTTCAACGTTTTTCGCCTGAAACGCTGGAAAATGCA
+GAAAATGGTTTTTTTAGTGGAAAATAAAAATATTTTTTAAAAAAACGAGA
+ATTTTTTTTTCGTCGAAAGTTCCAACAAAAATTACATGTTTTACAAAACA
+TGTAATTTTTGTTGGAACGTCTTTTTTTTCTGAATTTTTCTTTGATTTTG
+TTAACTTTCTGAATTTCAATTCAAATCGGCAAAATTGTACGCGTCTTTTG
+AATGTTCCCACATCTATTTTGTAACGAATACGGGAAAAAATATTTCAAAA
+AGGCACATTTTTCAAGTGTTTCCGCCTTATAAAAAATTGCCACTTCCGGC
+AAATTGATATCCGACATACGGCAAATCGGCGAACTGACAAATTGCCGGAA
+TCGAAAGATTCCGGCAAACCGACAACCCTCCGATTTGCCGGTGTCAGAAA
+ATTGAAAAGTGTAGAAAAATGACGTCACAACTAAATTATAATACATGTCA
+TTTCTTAATGTATTTTAATACAGTTTTGACGTCATTTTTCTCCACTTTTC
+ATTTTTCCGGCACTACTTGAATAACCCTGTATACCACTTTTAAAAATCAT
+GTTTTACAAATTTGTAAACTCCAGATTACTCCGCGGCAAACCGGACGGAA
+CCTTCCTAGTACGTGAATCCACAAATTTCCCCGGCGACTTCACACTATGT
+ATGTCGTTTCACGGAAAAGTCGAACACTATCGCATCGAACAGACGTCCGG
+CGGACAGCTGACCTGTGACAAGGAAGAATACTTTTCCAATTTGACACAGT
+TGGTCTCGGTGAGTCATTTCGGGGCTGTAGAGACAGGAAAAGGGGGAGGA
+ATGGGTAATGAACCGGTATTCGTTAGAATGAGACAGGTGAAGATAACAGT
+TATGATTTTATATTGTGAAGAGTTGTATTATAAAAAAGGTTGGTAGAGAT
+TTGAATATTTGGGAGAAAGAGAAAATGAGGGGAAAATTGTTAAAATTCGG
+ATTTAAGTTTGAAAAGTCACAAAAATGTTATATAAATATTTATATTTATT
+GGATATAACTAATTAAGATTTTATATAGCAATACTTTAAATAATATGAAT
+ATTGTTAAATATTGATATAATATCATATCAATCTTCATTTAATGGCTAAT
+TGTAATTTCCAATTTTCCAGCACTACAAACGTGACGCGGACGGTCTCTGC
+CATCGCCTGGTAACTCCGATTATTTGTGAAACAGCGACATTTTCATCAAA
+CGGATCATCGTCATTTGGTTCATCGTCGACAGTTGATTTGGAAGATCGAA
+CATCAGTATTTCGACACGCGGGTCTAGTTATTTCATCGAACGATATTGAT
+GTTGGTGATACAATTGGACACGGAGAATTTGGAGATGTTCGATTGGGAAC
+TTATAAGAATCGAAAAGTCGCGTTAAAAGTGTCGAAAAGGCATGGAAATG
+GAATGTTGGACTCATTGCTGGATGAAGCCAAGTTTATGGTGTAAGTTATC
+AAATTATTGAGAAGAAAATAATTTTGGCAAAGCCCAAAACAATGCGTGTT
+GAACAAAGTCATATTAAAAATATATTTATGTTTCAAAAATGTTATAATTC
+AATTTATTTTTAATTTCGAAAATCTATAATAACAACTTTTCCAAGTTTTT
+AGTTATGAGTACCCCGAAATCTGAAAAATATTTTCAATTGACTCCAAATT
+TGCCCCTGATTCCGAAAATCTAAGTGAAAAATTCGAAACCTGATGGGCGC
+ACAAATTATTTGTACAATTTAAACACTTTTTAATTAAGATTAAAAATTTC
+CCCAATTTTTTTGAAAATATTCATTAATTTCTATTTTATGTTAATAATTG
+TTTCAGTTTATAACGCTTAGTTTCAAAATTTTCAATTTTCCTGATTGATG
+ACTGATAACTAATGGCAGCAAATAAATCTGAAAAATTCCGAATTTTGCAG
+AGGTCTCTCGCATCCAAATCTAGTGACACTTGTCGGTGTTGTACTGGATG
+ATGTGAATGTCTACATGATAACTGAATATATGGCAAATGGTAATTTAATC
+GATTTACTCCGATCTCGAGGAAGGCATGCGTTGGAGAGGAGGCAGTTGAT
+GATGTTTGCGATGTAAGAAAAAGTTGACAAATAAAAAAATTGGAATTTAA
+CATTCAAATTAGATTGTTCAAAAATTGTTGACATTTCTGCATTTTTATAA
+CCGAAAAATCGAAATTTCATTTTTTCCGCCTGAGTAATAGTAACTCACCA
+CGAAAAGGGTTACTGTAGCAGTGCTTTTAGCTGTCTCTGGTTTAGAAATT
+TACGATTTGCCGGTCTGTCTGAAACCCGATTTTTTCTAGATTTTAAACAA
+TTTTCTAGTATCCTGTTGAATTAATTCCAAAAACATTTTTTGCTAAATTT
+TTGTTCTCCGTTTGTCAAAAAGCCGACTTTTTAAAAACACTGCAAAATTT
+CTCTCTAAGTTTTTTAAAAAATGTTTGCCCTTGAAATCAATGCAGTTTTT
+TTTTTAAATTTTATTTTGGAGTTTTTTCGAACAAAAATTTATTTCTTCGT
+CTATTCGTACCGAAACACCAAAAAATCCACTTTTTTTCGAAATTTTTTTT
+TTCAAACAACAACCCTGATTTCAAGGGTAAACATTTTTTAAAAAATTTGA
+AAAAAATATTGTAAAATCGGTTTTAGTTTTTAAAAAAAGTCGTTTAAATT
+TGTTGCACAATTAAAAAAAAATTTAGAGAAAAATCTTGCAATGCTTCAGG
+CACACAGCTGAAAATGCTAATACAGTACTGCTTTTCGTGGTTGGACCCAG
+CCGTGGTTACTGTACCTCCGGCAAAGTGGAAAATTCGATTTTTTTTTGTT
+AGAAAATTTGAAAATGTCAAAGATCTGATTTGAATGTTTCAATTTTTTGT
+GACAGCTGTTCTTGAAATCCAAATTTTCAACTTTTTTTCCATTTTCAGGG
+ATATTTGCCAAGGAATGTGTTATCTGGAATCAAAACAGATTGTTCATCGA
+GACTTGGCCGCTCGAAATGTCCTACTCGACGATGATTTAGTAGCGAAAGT
+TTCGGATTTTGGATTAGCGAAAAAAGCAAACAGCCAGTCACATGATTCGG
+CTTCTGGCAAATTTCCGATTAAATGGACGGCACCTGAAGCGCTTAGACAT
+AGTGTAAGTTTGGTTGAAAAATTGAAAAAAATTGAGAAATTTTTACAGAA
+TTTATTCTTTCAAAATTAATTTCATAAAAAGAAACAAAATCATTTCAATT
+TAAATTGGAATTTCGTATTCTTAAATTTTTAATTTAAAAAAATCGATATT
+TTTTAAATTTAACAAAATTTGAAAAAAGAAATCCGAAAATCCGCCGGAAA
+ATGCCTCAAAAATCTGCACTTTTTTTGAATTTTTGCCCAAATTTCTAGAA
+TTTTCCCTTACTTCATTTTCTTTCATAGCTTGAATATCAAAAATGGGAAA
+ATCTTGAAAAAAAATCCCAAAAAAATAAAAAACGAAAAAATCGATTTTCA
+AAAGTTTATTTTTTAAAAATTTTTGTGATTTTTTTCTGATAAAAATAGTT
+TGAAACTAGAATTTTTAGAAAATATCCAAATTTTCTAATAGTTCGCTGAA
+AAATGACTCAAAAATCACCAAAAAATATTGAATTTTCGCATAAATTTTTC
+AAAAATGGAATTTTTTTCATTAAAAATTAAGAATTTTTGCAATTTTCCCA
+AATTTTTTTTAGCAATTCACCACAAAATCCGATGTTTGGTCATTCGGCAT
+TCTTCTTTGGGAAATTTTTTCATTCGGACGAGTACCGTACCCAAGAATTG
+TGAGTTTTCAGACAACATTTTTTTAATTAAAAAAATTTCTCGTGTTTTTT
+CATATTATTCCTCGCTAGCTGTTGTTTTTATTTCTTGGTTGGGATCATTT
+CTTTTAAGGCTCCACGGAAAGGGAATCTGCGCGAGAATGAGATCTACGAA
+AATGAGCGACGATGCTAGGATGAAACGCGCGTTGTTTAGCATGTTTTTGA
+GACTTTTCAAAAATAGAGTTTTTAACCTTTTTCGTAGATCCTCTTCTCGT
+AGATTCCTTTTTCGTGGGTCCTCTTCCTATATTTTCGGCTTGGCCGAGTT
+TTCTCCCGGCCACGATCATCACTATTTTATTGATTTTTGTCATGATTTTC
+AGGGAGCCGATGGTCGTTCGGTATGTGTATATTGCATTTTTTCGTTAGGT
+TCTATTTTTTTCAAATTCTATCCACTTCTATTATACAATACATCTCACTA
+TCTTTTCCCCTGCCTGAAATTTTTGAAAAAAAATGAAGAAATTTTAATTT
+TAAACTTTTTCCAAAATTTTCCAAAAAAAAAAGTTTTTTATCAATTTTTT
+CAATAGCTCGAATTCTGAAAATGAAAAATGATGATAGAAATTGTTTTAAA
+AAAATGATTTTTTTTGTTGCAAAATTTAATTTTTAAATCGAAATACAACG
+TTTTTTTCAAAAAAAAAACACCTTATTCGAGACAAAAATAAGTTTCTTTT
+TTTTTCAAAATTGAACATTTGGATTTTCTGGAAAATTGAATAATTAAAAA
+AGATTAAATGTTCGAAAAAAAGAGAAATATATATTTATTGGCTTATTTGG
+AAAAATCAAAAAATAGTAAGAAAAAAATCAAAATTGTTCGATTTTTTATT
+TTTGTTTTGTTTCCGAAGATGTCCTTGTGGTATATAGTATTTTGGGTCCC
+ACCACGAAAATCGCCGTGCGCCTTTAAATTCGGCCGACCACGTCTCGCCT
+AAGTCCAGTCCCCCACTAATGTCAAAAAAAATTTTTTTTCGCAAAACCTG
+AATTTTGAAATCTTTTTTCCAAAAAAAAAAACGTTTTTTATTTAATTTTA
+AAAGAAAAAATTGGAAAAAAGTATTATTTTTTCTAATTTTGAACTTTTTA
+AAAAAATTATTACACATTATCTGGATTTTCAAAATTTTCCATATTCGATG
+TTAAAAATTATAAACATTTTTCAGAAAGGAACACCGAAATTTTTTTTAGA
+AAAAAGTCAAATTTGGAGCGAAAATTATGTTTTTCAACAATTTTTCAACA
+ATAATTTTGTTCAATTTTTTTTTTGGATCCAAAAAAATCTGTGTGTTTTT
+GTGTGATTTCCGGCACCCAACTCCCCAGAATTTCCCTCAAAAACTCTATT
+TTTTTCTCTGCTACCTCTTCTCAATCTTCTAATTAATTCTATGTTTTTTC
+ACTATTTTTTATTATTTTTTCACCCCTTTCAGAGCTCATTTAGAGCCCAA
+AAATAACCATCAGAAACACAAAAAAAACAACTTTTTTTTTCTTTTTGAAT
+TAATTTTTTCAGCCTATCCAAGACGTTGTGAGATATATTGAGAAGGGATA
+TCGAATGGAAGCACCTGAAGGATGTCCACCGGAAATTTTCAAGGTTATGA
+ATGAAACATGGGCTCTATCGGCACAAGATCGACCGTCTTTTGGACAGGTA
+GATTTTTTAAGGGAAATTTTTTAGAATTTTAAGACGAAAATCTGAAAAAA
+AAACCTACAATTATGGCAATTTTTGTGATGAAAATCTACAAAATTGAATT
+TTTTTTCGAAAACCTGATAGAAAAAAGAATAAAAATTAATTTGAAAAATG
+CCGTAAATTGACCAAAAATATGGAATTTTTACCAAAATTTCAGGGGTTTT
+TCAGATTTTACCAGAGTTTCTGCCTTATAAATTAAAAATTTCAAAGAGAA
+ATATCTTTTTAAAATCAGCATTTTTAGCAATTTTTGTGATGAAAATTGTT
+TAAAAATTGCCAAAAATGGGAATGTTTGAAGAAAATTCAGAAAAATCTAA
+ATTTTGGGCAATTTTTGCAATAAAATTGAAAGATTCGGAAAATAATAAAT
+TTTTCGAAATCCTGAAAAAATTTCACAATTTTTGCGAAAAGAATTGTAGA
+AAATTCGAAATTTTATTATTAAAAATATTGAAAAAAACAAAAAATTTCAA
+AAATCCGCCGAAAATGGCTTAAAAATCTAAAAGAAAAGATTTTTTGCATT
+AAATTTTATTGCATTAGTATTTGCGAAAAACAAACCCGAAAATTCACTCT
+AAAATTACAAAAATTTCAATTTTCTGAAGCTGCGTCCACAAAATGGCTTT
+AAAAATCATTTTCATGTACAATGTCAAAATTTTAAAAAAAGTGAAATTTT
+GTTCAGAAGTTACTATAATAAAGGTTTTTTGCTTTCCGGTCATTTTTTTG
+AATTTTGGAACATTAACCGAAAAAAAAATTCCGCATTTTTACCCTGAAAA
+ATGCGAAAATGTTTGAATTTTTTGAAAATTCCACTTAAATTTTTTATATT
+TTCAGGTCTTGCAACGATTGACAACCATCCGAAATACAGTATGACATCGG
+CGCACATCTCGAAACTTCCAGAAATCCATCGAATTTTCTAGTCCATATGA
+TGTTTCTGTTTTTTTTTCGCTGTTTTTTACACAAATTTTGTCATATTTTA
+TTGTAATTTCCCCCACACATTTTTAGGCATCGTTATTATATATTTTCTAA
+TCCGCTGCCGCGCATTTCGGGAGATCCTGGAATTTAAAGGCACAGCGGTG
+TTTTTGGATGGGTCCCACCGCGAAAATTATTATGCGCCTTTGAAATTTTT
+TTTTCGATATTCCTAAAAATCACAAAAAACATTTTTTTTTCTAAATTAGA
+GAAGTTTTAGCCTTTCTTTCGAAAAGTCGATTTTTTTGGTTTAAATTTTT
+CTCGATTTGAAAAAAATTTCAATTTTTAGTGAAATCAAAGAAAAAACATC
+AAGAAACTTCTATTCGAAAGAATTTTTTAAAATTGTATTTTCCGAAATAA
+TTTTCTCTGTTGGGTCTCACCACGAAAATCGTCATGCACCTTTAAATTTC
+CTTGCCCACACCTCTCCGAACGGCCGATACCCAATCTACGGTTTCTTCAA
+TTTTCCTCTGCATTTTTCATCGATTTTTAAAAATTTTTATCGAATATTTT
+CACGTTTAAAATTATTAATTTGCAACGAATTTCCCTCAACAAAAAATGCT
+CAAAACTCCGCCCCTTTATTGGCATAATTTTTGCCGCCACGGAAAATGCA
+ATAAATTTTATATTACTTTTCACCGATTTTTTAAGATTATTTTTAGAACT
+TTTAGTTTTTGTATGTGTGTGTGCTCGTAGTTTATCGGCAAGAAATTATT
+GTTTTTTTTTCTTAATTTTTAATAAGGGAACATTTTTTAAAGAGATTTTC
+AGAAAATCGGTAAAGATTTAAGATGCTCTGAATATGTCCAACTTCACAAG
+CTTCGTAGATTACGCGGAAAAGGTGATTTTGAATGTTGAATGTGCAAGTG
+CGCCCTATGGATAAATGGAGCAGCGTGGCAATTCGAAAAAATTTAAATAA
+AAACGTATTACTCGAAAGTTCACAGAGTTTTTCACCAAAAAATTGAAAAT
+TCGCTGAAAAAGTCGCGGGACATTCCATTTTTATTTTTCGGGAAGAAATT
+CGAGAATTGACTGAAAAAAGCGCGTCTTTATTCCAGAAATTTTAGCGGAA
+AATTCCAGATTTTTTTATTTAAAAAGACTCAAAACATGAAAAAAATATTC
+TGGAGAAATCAAAAATTGATTGAAAAGTTTCAGTTTTAGGCTAAAATTTT
+TTTGCGAAAAATTCATTTAGTTTTTGTTGGTAAAGTTCCGATTTTTCTGC
+AAAATTTGAATTTCTTTCTGAAAAAGTGCGTTTTTTTTTTCAAAAAATTC
+TTAAAATCGGAAATTTTTCGCCCCGAAACTGAACCGAAAAATTCGAAAAA
+TGAAGCGCGGTCAATTTTTGAATTTTGGCATTGAAAATATTCTGAAAAAT
+TCAAAAATTGACGGAAAAGCTCAAAGTTTTTCACAATATAATCGATATTT
+TCTCATTTTTCAATGTAAAAATCGATAGTTTCAGCCGCACGTCGCAGCAA
+CAAGCCAGACACCAATACCGCCGTCACCGTTGAACGAAAAACGGCCAATT
+CCACTGTTTCCAAGTGAATTTATCGATTTTTCTGTAGAAAAATCTGAAAA
+TTTCTGAATTTTCAGACGAAATCAGCAGCTCTTCGTGCGATGACGTCTCG
+TTTTCCATGCAATTCGGAGAATCTGAGCAGGGACATGTTATATGTACAAA
+AGTTCGACTTCGATTCTATCCTGCCGTGGTGAAAGAGGTTCGAAATTCAA
+AAAAAAAAGAAAACAATATTACTATACATTCGTAAAAATTAAATTTCAGT
+TTAAAGGCGCATCTCACATTTAAATATGCATTATTATTCATTAGTGTCGA
+CCCAGATTGAAAGCGCATGCAAATTTTGAACTTTAAAACTGGAAAAAAAA
+TTTTATTACACATTCGTGTAACATGAATATTCAGTTTAAAGGCGCGTGCT
+AGTTTTAAACTTCAAAAATTAAAAAAATATATATATATTCGTGAAAAAAT
+GTTCTTTTTAAAAGCTCTTTAAAAGTTTAAAAATGATTATTATACGTTTC
+TCAAAATTTTCAAAAATCAGGTCAAATGCACTTAGAATATTGGAAAATAT
+GAAGAAAAATCTTTATACATTCCTGAAAAAATACGCATGGTCCAAAAGTC
+GACAAATCGTGGCCCAATATTTTCTATTTTTTCAGAGAAATCTTCCGCAA
+AGGTCGAAATTTTTCGACGATTTCTACGATGTTCCGCTCACTGCGATCGC
+CAGAATTGAGGTGGCCATTGTGAAAGGTGAAAAATATTTTTACTTCAAAA
+AATTATTATATTAAATTTACACATACACATTCGTGAAAAAATTTTGCCGG
+TAAAAATAATGAAAAATATATACAGAAAAATACGGAAAATTTGGATGAAA
+AATATTTTTTGGTGACAATTAGAATATTACCCGCAAACAAAATTCAAATG
+AATTTTTTCAGTTTTTGAAAATCTAAACAAATTTCAAAATGTTATTATAG
+ATTCGTGAAAAATTAAAACTCAGTTTAAAGGCGCATTTCATATTCAAATG
+AGAATTATTAAACATCTTAAAGACATAAACAAAAAAAATGAAATCTGAAG
+AAGAAAAATTATACATTCGTGAAAGTTGGGAACAAAATTTTGTAATTTGA
+GTGCTTGACATCAGTTTAATAAAAAATTTTGAAACCAAGAATTTTCGAAA
+AAAAATCACGTATACCTAAAAACTTGTAGTTTTTTAAAGTTAGTAAACTA
+TTTTCTCTCAAAAATTCAAAAATATTCCAGGTAACAGTAAAGGAAAAGCG
+GACAAATTTCAACGCCTCGAGACAAGCCTATCAACAATGGAAACAGTATC
+AATAATTCGTCTAATATTAAAAGATGTCAGAGTTGTTACAATTGACTTGA
+GAAGATCTCAAAATGCAAATATATTGGCTAATCAAATACTCTACTTCTCG
+AAAAGTGGACCAATCGAAAAAATGACTCAAGTTGGAGCTGCTATGGAGGA
+GCGCGGTGTGAAGGCGAAAAGTAGGCATTGGATAATTAGTATTGGGGGTT
+GGGAGGGGAGGGAGGAAAGTTCGAGAAAATCGGAATATCTTATAAATATT
+AGGCCGTTTGATTAATAAATCGACACATCAAGTAAATAAATTTTGAAACA
+AATTAAAAATTTTAAACGTTTCGATTGATATATGTGTATCAATTTTTTAA
+AAGATGTATATTAGTAACAAACAAGAAATTTTTTATTCAATAAAAATATA
+CTACGGGAGCACTAAATTTTTAGAATGCGTATTGCACAACATATTGGACC
+AGATATCTCGTAGCGAAAACTACAGTAATTCTTTAAATGACTGGTGTCGA
+TTTACGGGCTCTTTTTTCATTTCTCCGTATTATTTTCTCTTTTTTGCTTA
+ATTTTAATATTCTATCTATAACTAAAAAATTAATTCATTTCGAAAATCTA
+GCCCGTAAATCGACACAAGCGCTACAGTAGTCATTTAAAGGATTACTGTA
+ATTTCGCTACGCGATACTTTGTGCGTCAAATATATTGTGCATTACGCATT
+TTCAGAATTTTGTATTCTCGTAAAATTTTCGAAAAAGTAAATCTTTTAAA
+AAACTTTTTATTAAATGAATAAAAACGCATTTTTTGGAGAATCGGATAAA
+AATAATTTATTTAAGTTTTGAAATTTTAATATTTTGAAAAAAAAACATTT
+TAATTGGAAAAAAATATGAAACTTTCTTTTGTAAATATGGTTTTTACAAA
+ATTCCCGAATGTCCAATATACAAACTTATCATTTTCCAGCAGCATTCAAT
+AGCTACGAAGCATGGCGTTCGGAACTCCAAAGGTGCCAGCAGAAGACGGA
+TTCAACGTCTGTCTGGAAAATTGTAGCACTTAACAAAGAAGGCTTCAACT
+ATGCGGCTCAGGGGTGCGATTTTTGGAAAAAAAAACTGGATTTCCGATTA
+AAAATATGTATAGTGTATGTATTTTTCAAATTTCCAGCTACCCTGTGTAC
+GTAGTAGTGAGCAACTTCTTGGATCGTGTGGACATTGAACGACAACTACA
+ACACTACAAACAAGGACGATTTCCGATTTGGGTGTGGTCTCGGGCGAACG
+GACACTCGGCGTTATTCGTTTCGGCGGATCACGAGAACAATATCGCGATG
+CCGGCGATTTTGGCGAAGTTAGTACATTATATTTTAAATTTGTAAAATGT
+TATTTTCTTCCAGAATGCAAGAAAGTATCACCCGTTGCCATCCGAATAAC
+GAGAAGCCGCATGTTATAAAATTGGACGTCGATTTTGTGTCGAATGTTGG
+AAAAGCTTTTGATAATCTTCTATCGCTTTGTGCAATTGGTGAGGGAGAGC
+ATTTCATATTTAAAAAAAAAATTATTCGCCGTATTTTCAGCTGTTTTATT
+TTCCATTATTTTCCATATAATATGCATTTTCCCAGACTCCTACGAGCAAT
+ACGTTACACTGCAAAACGGTTGGAATACGAAACTCTCGAGAACCGGATGG
+CTTCATCTCGTCAAGCTGTGCCTTCAGACTACCTATCAGACGATTCAATG
+GATTGTTGATAGAGATCGATCGGTTATTTTACAGGGTACTATCAATTTAG
+GTTTTATTCAGAGAGAGAGAGATAGCAATTTTCAAAATATTTACAAACGA
+GTTAGTCATTTACATCCACAATCGACTGATCAGAATCTGATTCGTGGCCG
+TTTTCCTCCGCCAGAACTTTAGGAACTTGCACCGAACTACTTGCTGCTTG
+ATCCTCCCCCTCCAGAGGATCTTCTCCAGATGGGATACAACTTTTGATGA
+AGCTGATCATCGGATCCTCCTCTCCATCATCCGAACTAGTTTGTCTGAGA
+AGAATATCAACCAGTGTCTGCATTAAATCACCGGGTTCCGTTCTTGCTCG
+TCGAGTACTCAAATTGTGTCGGCACATGAATTTGTCCAACCATCCGCGGG
+ATGCCTGAATGATAAAGGTGGAGTAGCGTCGAATAGTTATTTTTTATGTT
+TTTCATATACTCGTTTGCATTAAAGTAACGGCTCTCCTACCTTGAAATCC
+GAGTTCTGACTGATTTTCTTTGCCGTTTCACCGATGATTCTTCTGGTGAC
+TCGTTGTTTCTCCTTACGCTGATCGTGAACCCATTTAATCAATTCCTTAT
+CAACGTCGTCATACTTTAAAGGTCTTCCACCTCCCGAAAGTCGCTTTGTT
+GCAGTTGAGCCGTTGTCTTCTCTGAAAGTGTTATTTGCCAAAAGGCAGCA
+AGTCGAAAATTTTTCAAAAAGAAAATTTGAAATCGAACAGAGAATTTATG
+TTATGCCCGTATTTCAAAATATAGGAATAGTTGAAATGACTTCTTTTGAT
+AGGATTAATTATAAGCCTAGAAAAAATCATAGTATTTGGAATAAAAGGTC
+CATAAAAGGTTCTCAATTGATAGGGCTTGCATGTAGGCGTTAAACCCTGC
+CTTTAAGGCGACCTCCGCTTGCCTCTCGGTTACGCCTTACGTTGTGCTAA
+AACATAATCAATCTTTTTTTTTTTAATTTCTATTTTGATTTTCATCAAAT
+TGAGAGAAATGAGAAAATTAGAAATTTGTAAATTCACATAGGCGGGTTTC
+AAGCAGGACCCTGACACCGCGCATGCCTAACATGAAAGTCCTAGCCCTGG
+ACTATTTTTTTGAACACAAAAATATGTCCGAAGTGGCAAAACTTACAACT
+GCTTCTCGATTTCAGCTTTCTGGGCGATCCACTGTTGAATGTTTTGCCTA
+TTCACATTCAAATCCTTTGCTGCTTTCGATATATTCTTATGTTCAAGGGC
+ATAATTTATGGCATGCAGTTTGAACTTCAAGTCATACGTTCTTTTTCGAG
+TTTTTACAGGCACTTCTGTAGGGATTTCGCTCATTGGTTTTCTCTGAAAA
+ATAAGTATATAACAAGCAAAGTCTTAACTAGTCAGCAAGTTATTGGAAAT
+AAAACATGTGAGAAAAGCGAACGAAGGGGCAAGACTAATGGAGACAGCAA
+ATTGGCACACACGCAGAGAGACATGGCTAATAGAGTGTGCAAGACTATTA
+GAGGGTAGAGGCAGTGAGACGAATTTCCGACTGGTCAGAATGTAAAGGGG
+GTGCAAGGCTAATAGGAGGAGACAAGACAAATAGAAAAACTACATTATTA
+TATGAAAAGAGAGTAAGACTGAATACGTGTATGGGCACCCCACATATTTG
+TATGTAAGTAGTTATGTAAATGACTTTTTGGAATTGAAAAGAAAATACCA
+AGAAATGGAAAAAACCTCCGGTCAATCGTAAAAAAATTATGAAAGAAGTT
+CGATCTACTCGGCTACGATTTACAGTTTCCCTTACTGATTTCTACTAAAA
+TGCATTAATCTTGAGTTTATCTCTAACAAATTGATGGTACTTTTGAATGG
+TTATAACACCGGATATTTTGCAGAAGACGAAGGATCAGATATGTCGATTA
+TTGTGGCCAGCCTCACGCAAATGTGCTGTGATCCATTTTACAGAACAACT
+ACGGGTGAGTTTATTAAATGTTTTTTCTGTACTAAAAATGGGGTTTAAAA
+AACTAATTTTAATTTAGTTCTCTCCTTGTATTAATTTCCAAAATTTTCCG
+AAATTTTTTTTTCAATTTAAAAATCAATTTCAGGTCTTCAACAACTCATC
+GAAAAAATGTGGATTGCCCTTGGCCACCCATTTGGTGAACGGCTACTCGG
+AAGAACCGACGATGATCCATCGAGACGTGGAAAACCACAGAATAAAATGA
+GAACTGACGTCATGCCGACGTGGTTGCTCTTCTTGGATTGTGTTTCACAG
+CTACATCGAATATATACATTTGAGTAGGTTTGGTAAAAAAAATGTTTTCC
+CCCGCAAAAAAATGTTTTCCTCAAAAAATTTGAATTTCCCACCCAAAATT
+TTTCTCAAAAATTTTTTTAAAAATTAATTTTAAAATTGTTTTCTCAAAAA
+ATTTGAATCTCCCGGATTTAAAAATTCCAAAAATTCGTCTATCAATAAAT
+TTTATATTGTTTTCGAATTTCGAATCATAAAAATTAGTTTCAAGTTAACA
+CACCTTTTTTTTCAAATAATTTTTTTAAAAAATAATTTTAAAAACAATTA
+ATTTTTTTCCTATTTCCAGATTCACATTCTCTCCACACGTTCTCATTGCA
+CTATGGGATCTTTCATTAACTGGAATGGTTCCATCAATGGCTTGTAATAA
+TCTGGAAGAGCAATTACTCGCAAAAGTCGGCGGTGGACCATTCCCATTGG
+ATCGATATTTTGAGAAAAGCTACTCGAAATTATTTGGAAATATTTGGCAC
+GACGCAGTGCTTTTTATGGAATCTATTAAGAAAAGTTGGTGCTTTTTAAG
+AAAAAAATTTTATATCGATTGTTCTTTTCTTTTTGATTTCAGCTACTTTT
+TCACCTCGGTCAGCAACATTTTTTTGCAACATTTTGGACGTGGCCGCGAA
+AAAAAAATTGGTGGCCGAGTTTTCTTTTTTTTCACTGCCATTAATTTCCG
+AGAGGAAAATCTAGGAATTAAAATTTTTTCGAAAGTATACAATGTTGACC
+GAGAAAAAATCGGTGGCCGAATTTTCTCTTTCTTCTCTGCCACGTTATTT
+TAGTAAAAAATTAGAAAAAAAAACACAAAATGTTGTTCAAATTTTGGAAA
+AAGTCTGTAAAAACAACAAAAAATTGATGGCCGAGTTTTTTTTCCATTTT
+CGCGGCCACGTGACAAGCAGTGATTTCTCAAATGTTTTCAGGAAAAAAAA
+ACAGGCGGAATTCAGATAATTCTACGAAAACTATTTTTGTTTCTGGAAAA
+AAGTCAAAACTTGAAAATCGGTGGTCGAGTGTTCTCTTTTTTTGCGGCCT
+TATCTCGATTTTTCCAGATCAACCAGTGTGTGCTCACTCGAAATTCCTTC
+AATGTGAATTTATTCGGCCACCGACGTCGTTTTGCGATATTCAACTGTGG
+TCCGAGTGCTATCTTCGATGGATTCCTCCGGCAAACGGGAAAAATTCGGG
+AAAACTCGGCGAAGAACTCTCGCTGGACGAGAAAATGATCGAAATGGCCA
+AAAAATGGAACAGTTCCGAGTGGAAAATGCATTTGGACCTACCGGAAGAG
+GTGACCAAACTTTTCGGATTTATAGGCTCTAAACATATTTTTACTTTCAA
+TTCTTAAATTTTTAGTATTCATCTGCATATCCTTACTCGATTCCGGAGAT
+TTCCCGCCCAATAATGGATTTAAATGATTTTGATATGATCCGGCCGGATG
+ATTTCGACGCAATGTCCATGAATTCATCCATCAACTCATATTCGTTCGTT
+AATACGGTAGGGATACTTATTAGCTCGGAAAATAAATTACGACATATTTT
+GTCTCGAATTTTTTATAGGTGACTTATAATAGACATTTAGTGTCTAGGCA
+CACATAAAAGTTAGATCTTTTTCAGCTATCGTTTCGATACTTTCACACAA
+AAGTAGGTTTTTTTTCGCAACTTTGTAAATTGAAAAATCAATAGGTCGGC
+AAATAATTGTTGGCGTATTTTGTCAATTCACGATATTTATCAAAAATTTT
+ATATGTGACTTCTGGTAGAAATTTATTATGGTTGGCAATAAGTACTGAGT
+CAAAATTCATATAACTTGTTTTGTTGCTTATCGATTTTTTTTAATTGCCG
+GAGTTCATGTTATTAACTATGGGCTTTCATCTGAAAGTAGTCACAAAACA
+TTTTAAAAACTCGAAGTGATCCAAGTCGAAACAACTTTTTCAAGGTTTAC
+GCCCTCTTATTTTTTCTCTTATTTTCAGCATTGATATGAGTTTATGTACG
+GATCAAGAGTGTCGGTTTTTCGATTTTTGTATAAAATCGAAATTTTTTTT
+TTGATTTTTCGATTTTCCCTGAAAAACACACAATTGAAAAATGTCACTCT
+TGGTACGGATATTGCTAAATCTATTATACAATGTGAGAATCCAATAAAAG
+TTTTATATTTTATTTTTGCAGCCAGTTCGTAACAACACGACAACAGAATC
+AATATTCGATCATTCGACACTTGAGAAACGAAATCGTCGAGCAGCTGCCA
+CAATTGGCTCCGAATCGCCAGTTATTCAAATGAGACCAAAAGAGCAAATT
+GTCGGATATTCGAAATATGCATTTGATGATTCATTATCACCAAGACCACA
+TTCCCGAACTGTTGAGACGCCTATTTTAAAGAATGTACGGGATTTTTGGA
+AAATTTAAAATTTGGAAAATGAAAAATTCAAACAAAACAATTTTTTCGCT
+TTCAAATTTCATAAAAATTTATGTTAAAAATAGTTTTTAATTGAATTTTT
+AAAAAATTCTTACTGAAAACTTTCGAAATAATTAAAAAAAAAAACCAAAC
+TATATTTGTTTTTTTATTATTGAAAAAGTTAAAAAAAATGTTTTTTTTTG
+ATAATTTTACACTGCTCGCCTTCAAAATTTGATGAAAATCTTAATACTAG
+ATTTTTTTAATTTTTCATTTAAGACTTTTCGAAAAATTCGAAAGTTCAAA
+AAAAAAAATCCAAAAAAAATTTCACTCAAATCAATCGCCTTCAAAATTTG
+ATAAAAACTCGATGAAAATTTTGTGGAATTAAAATGTTTAATTTATCATT
+CTGAGGCACCACGTTTTCAAGATCTGGTGGGATTCCGGATCTACATTCTT
+CATTTCAGCGCAAAATCCCTAAATCCGGAATTCCACCGAATCTTGAAACC
+GTGGTGCCTCATCATTCTACCTTTAAAAACTCGAAATTATAAAAAATTCT
+GCAAAACTCTAAAAAAATTTGATTTTCGATTTTCGAAAATTTATCTTTTT
+TTGTATTTAACATTCAATAAAATATTGATGAAAAAATTTCTAGAATCATA
+TTTTTAAATTTTGCTTTACAAAATTTTTTAAAAATCTACAATCGTTCACT
+TTCTTGCCTTCAAAATTTGAATGAAGAAAAAATTTCAAAAACTTTAAGAA
+TTAAATTTAAAATGTGCTCAAAAAATTCTTTAAAAATATGCGTTTCCCTA
+ATAATTTCCATGTTTCAGTCCCCATCGCCCTCCTACACCCCATTTCACCC
+GACGCCCGTTCACCGGAGCAACACCGTCCGTGCCGACAATCGCCCAATTC
+CCCCGCCCCGGCCGCAGGGCCTAGGAACACTGACCCCATCACGCCCCGAG
+ATAAGAGCTCATCGAGATGATATAGAGAGCCCTACTATTCGGGTCACAAG
+ATTTTGAAGAAAAAGTTATACTTTTATTTTAATTTCCGCTCAAAATCGGA
+ATTTTCTATAAATATGCCCCTTTAAATTGAGCTACAGTAGTCACGTCGAA
+AAATTTTCAATTTTTTTGAATTTTTTGAATTTTTTCATCCAGTTATAAAA
+AAAAGCTTGCCCCTCAGCTCTACCCCATTTTTCTTTCATTTGTCACCTAC
+TTCCTTCATATATGCCCGGTTAATTATGTATTTTTTGATGCTTTTTTAGT
+CCCGCCACGGTTTTTTTCATTTCGAAAAGTCGATCGATTATCGATTTTTT
+CGAAAATTTGGAAAATTTGGAGAAAATCTAAATATTATCGATTTTAAGCT
+AAAATTTTAAGATTTTATTTTTTCAAATAAAATTTTGGAAATGTTTTTTT
+GAAAAAAAAAGTGCAAAAAACACTCAAGGGAAAATTTTTAAAAAATTGGA
+AAAAATCTTGAAAGTTTGTCGATTTTTCAGTGTGCATTTTGGAGTTATCG
+GTTTTCTTTCCGAATTTTCATCAAATTTATTTTTGATCTACCAAAAAATC
+TCTAAAACCCCGTGGCGGGAACCTACTTCACTTTTATTCTGCATAATTAG
+ACAAAAATGTGATTATTTTCTCATTTCAAAACTTGTTACATATTTTGTGT
+TGTGATACATATGTCTAAATTTTTACGGACTGAAAAAATACTTTTTTCTT
+AATGTTTTTGAAATTTTCATTATTGGTGGCGTCATCCATGTCTATTTGAT
+TTTCCAGACCCCCCCCCCCCCCTCTAAAATGAAAAGAACAAGACGATTGA
+CAGCTAGCATGTGCGACGATCAAAGTACCGATTTGATTCAGTTGAAGGGA
+CACGAGAACGCGAAAAAGTCGGAAGCCCATCTGAAAGTGCTGGAATACAT
+TGGCAAACGCTATGAAATTCGAATGACCGACGGGCGGTACATACGTGGCA
+CGATGATCGCCACTGACAAGGACGCTAATATGGTTTTCAACAAGGTAAAA
+ATTTGATGAAAATTTGGTCCAAAAGCTCATAGTTTCAAATATTTTTCCTT
+AAAATTATGCGCCGCAGGCAAAACAACATTCCGCCTTTTTCTATTGCTGG
+CTTAGTTTTCGCAATTTTCTCGGCTACCAGGCTACTGCAAAAATGATCGA
+TCCGTGAATTGTGCAAACATCTGAGTTACACAGAGAGTGGGGCGGAGCGG
+AACATCGCAACACTGCCGCATGGTTTTTCCACAACTTTTTTTTTCAAGAA
+AGTTTCGATTGTACTTGTTTTTTCTCTTTTTTGTATAAAAATGGTATTCA
+TTCTAAATAATTCACATATGCTAAATTGCATATAAAAACATGGAATATCC
+TCTCAAATTAAGAGTCTTAATCTTATTAGAATTAAATTGGATATCATTTT
+CATTCGAAAAGAAAGAGAAAGAAACAAGTAAAATCGAAACTTTTTTGAAA
+AAAATGCTTGATTTTATTTCATTTTCGTTGTTTTTTTTTCAGTATTTAAC
+TTTTGAACGATCGATTATTTATAAGGTTTGCGGTTAAAAACGATGAATTT
+CGTGTTTTTCTTTTCTGGATTCAAATGACAAGTTTTAACCAATTCGAATG
+TCAAACACGGAAAAATAAGCGAAAATAACAAAAAATCGTGTATTGTAACC
+AAAAAGTTCTCCACGAGTAGTACACTAGAGCCGACGCGCCGCAGGTTTGC
+AAAACAACGCCCACCCCGTTTTCTGCGCGGCACTACACAATTTTCTATCT
+CACGAATAAATATTTCAGAAAAGGCAGGATTTTGTCTGAAAATCATGAAA
+AATCAAGTTTTTTTCAGGTTTCCAACGCTGAAATGGTTGGAATTAGGGTT
+TGTTACCAAAAATCGTATAATATTAAAATCCCAGTGCTTCTCTGTCTTTC
+AGCAATTTCTTTTAATTTCCAGGCAGACGAGCGATGGGACAAAGATCCAC
+AATTGAAAGGAGTCCGATTTCTAGGGCAAGCGATGATCTCGAAAAAGCAC
+GTGGAATCGATGCACGCGTTGCCGGACCCTAAAGAAACTGAAATTTGATC
+CAGTTTTCTTATTTTCTCTAATTTATCCCATCCTTTTCTTGTCAAGATTA
+ATATAAATTAATTTTTATCGAAGCGATTTTTGTTCATCTCATCCAAATAT
+GAAAAAACATTCGAAAAAAAATCGCAGGCTTCACTTGGAACCGCGCGCCA
+TCAGTTGAAAATGCTGAATATGTACAAAGACTGGAAAATATTAAATTTTT
+ATGTTTAAAATTTCACGTTTTTCGTGTTTTCCACAAAAAAGCAATGCATT
+GTCGTTTTTCAAAAAACACTCATGGTAAACGAAGTCCCCGTGGAGTACAC
+GACAATGTCGCATCGAGACCCAAACTGGGAAACGCCTGCGCCTTTAATTT
+TAGGAGTTTAATTTTCGAATTTCGAGTTATTTTTTTCTCAAGTCTTTTTG
+CGACTTTTTTTTGAATATTTTATTACTTGTAGCGCTGAAATATGACAGTT
+ATTATAGCGTCACACTGGGGACCTCAATCAAAACAGGTATTTTTCAAAAT
+TTCGCCGTAAAATCTAATAACCAATTTTGAGATGTTGCCACCCGAGCCCC
+CACGGATAATTCTGAGAGAAGTTCCGGTCCAGAATAACCAGAAAGAGCAT
+CCACCGGTTCAGGAGATCAAAACCGTGTCCAGCAAGTCGAAGGAACATCG
+CGTCAGTTCGAGCCGGAAAATTCCGGATCACTTCGACGTGGGCCCACGGT
+TCTACATGAATGTCCCCGCAGATGGCTCAGAAGTGTTCGAGGACGACGAA
+AAAGACGTCGAGAACGAGTGTTGGGCGGTGATCGAAAGAATAGGAAGCGA
+GGATGACAAGTTCGAGGCCTCTGAGCTTGTCGAGTACCGCGATCACGATT
+GGTACATCGCTTTGGCGATTAATAAGGAGAAAACGCCGGATAAGGCGAAT
+TATCAAGTAGGAATTACGAAAAAAATTTTGATTTTCAATCTCATTTTTTA
+AATTTCAGCACCTACTCTACAGCTATCGAGGCGGAATCCAACGCATAATT
+CTCACGCCTCAACAGACGGATTCGATCGACAAAACGCCGCTAGTGAAGTA
+CAAAATCATCGGAGACGGTCTGTACGAAGTGCTTCCGATTCACTCGTCCC
+TTCCTCAAACTGGTCTAATCAGTCCCAAATATCGTTACAACAAAGGCGTC
+GAGCTTCGGATTTTCGGGATAGTGAATTGGATTGATTTTGTGTTGGACGA
+CGATCATCAGACGCACAGGACGATGGTTTGGACAGATGCGGTCGGACCGA
+TCTATCTGAGTGCCGCGGATCGAGCCAATATTCGACGGAAGCTGCTGCTG
+ACCGAGATGCAGATTTTCGCGCCGTTGCGAATGTGCCATATTACTGTCAA
+GGCGGAATTTAACTTGTTAGTTAAAAAAAACGCGTAAAAAGAATAATAGT
+TCCAAATTTTCAGCTCGATTCCCGATGGTTCCCCGATTCAATGGACCATA
+TCATCGTTCCAGCCACTCATCGAAGAATCAGAGAAGGATCCGAATATTGG
+GCGCAATTTATGGCCAGCGAGAGTGCTCAGATTCGATGATTTAGTCGTTA
+CAAAGAAGGTGCTTAATCATTTTAATATTAAATTTTAACAGCATTTATAA
+TTATTTATCTATTTCCAGACACCGAACGGCTACTGGCTGAAGTCTCAAAG
+ATTGGAGGGTCACGTTAATGTGTTCGCCGGTGCAAATCAAATCGGAATCA
+TTGAGTCGGCGGGTGAAAAATACGCGACGAAGGGAAGCATGATGGCGTTC
+GTGGTTCCGTGCTATCAGAACAGCACGTTTGCATATTTCGAAGCACTTAT
+CGCCGGACCCCCGCGAGTCGTGATGATTATTACCGAAGGACGCTTTCTGA
+ATTATTGCCCGAAGACGTGGCCACCGTCTGTTCGGAAAATGCGTGATCAG
+TATCAGAAAGAGCACGTTGTAAGCACAATTTTCCAGAGAAAAAGGCTTTC
+GATAAATTTTCTTATTTTCAGCTGAAATCCGAAGTCCGAAGTTCACCAAT
+CTGCATGAAACAGCCGGATTATTGCCTCAAATCACTACGAGGATTCAGCG
+AGTGCCCATTTTGATCACTCAAAGTTTTATATATTTCTGTATTTCTTCTG
+CCTTATTTTAAAAAGTATTTTCCCGTTTTTTTTCTTTTGTTCAATTTTCC
+CTTTTTCTTTACTTGTTATGTCCTATGTTTCATGCTAAATTAACGTATAT
+TTTTAATTAGCAATTAAAAAACTTTCTGATTAACTGCCAGTTTTTGAGAA
+GAACCAGAAGATGGAACGCAGGCGAGTTTCTGAAACGGAAAGGGTTTGAA
+ATTTTTATCAATCAAACAAACTCGCAATTTTATCAAAAACCATGCCGTCG
+TTGCAAGTTTGAAAAAACCACATATATTTGCAACATTGATAGAATATCAT
+TGGATCGTATGGATCCGCCATGGCCAGACCATCATATTGACATGTACCGT
+TTAATGGGTTCGGTACCGCTGAAAAGTTGTTGGTCTCGCAGCGAAGTACT
+ACAGTAATCGGGAAAAAGCGCTGTTTATTATCGATTTTTCAATTAAAAAT
+CAATAAACTCGCCGCGAGATCCAAACCTCAACTTACGATAGCTTTTTGTA
+GGAGTCGATTGTCCATCGACAAGGAAGCCAGCAACTAGGAAAATTTTGAT
+AGGGAGAAGCATTGAAATTTAATTGTTTTTGGGGGTTTCGTTTGGTTTTT
+ATAGGAATTTTTGAGCTGTAAGAAAACAAAGCAACATTTATTTCAATTAA
+AACCGGAAAATATGAGTCATTATGGGGGGTTTTCAACCGTACGGAATTTG
+ACAAATTTGAAACTACCATAAAATGGTTAGTTTTGTAGTTAGAGAACTCA
+AAATTGATTTTCTAAGACAAAAAAATTGCCCTTTTTCAGAATATAGTAGG
+TTTGTATAATTTCCAAAAAATTATTTTTCTTGCCCAAAAAAAAAAGGACA
+GTCATTAGATGGCTGAAAAAAAAGTGGGCAAAAATAAAAAGTGTCTAATT
+TTGTTGAAAACGGGTAATTAATATATGCAGAATTCAGAAAATCTAGGTTT
+AACCCATCAAAAACCATTAAAAAGTGGCAAAATTTGGCAATTTTTGCAAA
+AACTCACAATTTTGAAACTCCTCTAAATTGGTTCAATTTGTAGCTAGAGA
+ACTTAAAATTGGTCTCCAAGCCCTAAAAAATTGTCCTTTTTCAAAATATA
+ATAGTTTTAAACGTTTTTAGAAAATTTATTTTTCTTGCCCAAAAAAAAGG
+ACAGTCATTAGATGGCTGAAAAAAATTGGGCAAAAATAAAAACTTGTCTA
+ATTTTGTTGAAAACGGGTAATTCATATATGCAGAATTCAGAAAATCTAGG
+TTTAACCCATCAAAAACCATTAAAAATCTAAAATGATTAATTTTCTAGTT
+AAAGGATTCAAAATTGATCTTCGAACACTAAAAAGTTGTCAAGTATCCAA
+AAAAAGTGGTTCAATTTAAAAAAAATTGGTCAGGGAAAATTATCGATTTT
+TTCGCCGCTTCGCAACTTGGACGAATTTTTCTTTCGCTGCACAAAAATCA
+ATAATTATTGATTTTTTTTCTAAAACAGAAAAATAGATATTTGCACTTTT
+CTGAAAAATCGATATTAAACGGAAATTCGCAAAAATCGATGGTCACTAAT
+TTTTTTGCAAAACCCCAGTAAAAAATCGCTTTTTTCGCCGCATTTCCTAA
+CTTTTTCTATGCCACCACTATTGATTTTTTTTCCAGAAATCTTGGAGCTT
+CCCAAACCCGCTCATCAGCCCGCGTGCTTCATCAATCATTCCGTTGAGAA
+CTATGAATTTTTCGAATGAAAATTAAAAAGAGGGGGATTTATTAGACTGA
+AAAAGTGTTTTTGTGCCACGTGGCGGCGGCCGAATTCTCCTGGACGGGAA
+TTTCTAGGCCATGCTTGGGGGAGATGAGGAGATGGGGGTCAACTTCAAAT
+GTGTGTAACAAAATAGAAAAAAAACTATAAAAGGTAAGAGGAGATCAAAG
+GTCACGCCACTAGGGCTTGAAAAATGAATGCCTGCCTACAAATAGACATG
+TAGGAATGTAGGCAGGCAGACAAAAAGTGGGTGAACAACGAGAAAAGGCA
+CGTAAAAAGGGGTAAAGGTTAGAGAAAAAGAAAAAAAAAGCTCACAGAGC
+ACATTAAAAATGGAAAAAAACGAGATCATTGGATATTCTGCTGCCGTTGA
+TCATCGTCATCATGAATGATCAGCTGATTGGGGTCGACTATCACATCATC
+TGGGTTCACGAGAGCATCTTCTTCGAGCAGCTCATGCGGAGGATGATCGT
+CGTGATGATTTGGCTCTTCCACAACCACTTGTTCGAGGACATCTGGAATT
+TATAGAATTAAAAAATACATTTTTTAGACAAGAAATCGACAAATTTCTGT
+GTTTATTTCTATTTTTCAGATAATTCCACACAATTAGATAGTTATTGAGT
+TTTCTTTCTATAAATTTCAAAAAAAAAAACGATAATTATTGATTTTTTTT
+TAAATCAAAAACTTCACAAAACTCAATAATTATATATTTTTCGTCCTCAT
+TCTCTTTCGGTTTTGTGTGTGTGTGAGTTTTTTTGAAAAACGCAAAATTT
+TCTGTGATATTTCTATTTTTTAACCTGACATGGGCAGTTTTTGAAAAAAT
+TTTGCAATATTTTCGGTGTTCTTTCTCAGAAAAACTCGAAAAATTGCAAA
+ATAAATGTAAAATTTATCAAAAATTACACATTTTCGGTCAACCTTTTGCT
+CAGAGAAACTAGAAAAAAAATTTCAATTTTTTTGGAAACCTGCCAAAAAA
+TGAAGTTTCAGTGAAACATTTTTTTTATCTTTTTTCGAAAATTTAATACA
+TTTTTTTGCAATTTTTTAATATCAATCCGTTCTCACATTTTTTGGTAAAA
+ATATGAGGAAAATGAATACATTTTGGATTTTTTCAGAAAATCTGTTTACC
+ATTAATCTGCTTCTCCCCAGTATAAACTTTAGGCTCATTCTCGTGCACTT
+CTTCTTCCAAATTAACATCATCACCAACTGTCCCAATAACTTCTTCCTCG
+ACAATTTCCTCAACAATTGCTCCATCAGGAGCCATATGCAAATGCATTTC
+TCCATTATCCATTTCTTCTCCAGCCATTATTTCGACTCCAAACGTGTGAT
+TCACTATTTGCAAGAGACGATGTTCGCTTTTTTCGAAGAGCATTTTGAAG
+AGCAAATCGAATGTCTCGTTGTCGGTTGCTGAGCCAAATGAGTTCTTGGC
+AATACGGAAGAGAGCCTCGTTTCGACTTGTTCCACGCGCCATTCCAGATT
+GTGATAGAGGCTGGAAATATTACTATTTCAGATTTTTAGATTAAATGTGG
+AGCTGGGAAATTCGAGTTTTCGACGAAAAAATAGCCTTTCAAAAGATTAT
+TTTCAGATATGTTTAAAAAAATTCCGTTGAAAACGACGAAATTAGATAAA
+AATTGGATTTTCAGCACATACACGGGCGTTTGATTACGTGGCCGTGAAAA
+CGGAGAAACTCGGCCACGTAGAAACAAAACCGAAAATTGCAGAAAATCCA
+GGAATTTTTTTTAATGACTCCGAAATTTCCCCGATTCCGAATAATATATA
+TGAATGAATATATACTTCTGAAAAATTTCAAAACCTTTGCTCACCAAGCC
+ACTACTCTGCTGCCCAAAATTTTTAGGCTCCTGATATTTCGCCTTTCTAT
+ACGGCAGCTGAATCTGTTGCTGGGATGATGATGGTTGCTGAATCTCTTCG
+GTATGTGAAACCTGAAGCTCTCGCTCGTCGAGCATCTCCTCAAGATGCAC
+ATTTTTCTTTCTGGATCCTCCTTCTGAAGCTTCTGCTGAAGCTCCAGCCG
+TGTCAGTCGTCCAATCATCCACAAAATCACCCGCCGCCGCCGAAACAATC
+ATCTCATTCTTCAACTCGTACGGATCATGATCATCTTCAGCATCCCGAAT
+ACCATCAGTCGCCGCCATAATCTCACGACGTCGTACATAATAGAGCATCT
+TCGTGTTCACCTGAATCCCATACTTCTCCAAAATCACTTTAGCCACCTCG
+GCAGGTGTCATTCTCGCGAGCAGCCGGAGCACATCCTCCCGAATGTGTGG
+TGGAAGACGTTGAAGTGAGTATTCTTGAGCGGAGCTCATCGTGCTCACGT
+TAACCGGAGCCGGCATCTCGCCGGGCTCAGTGTACCAGTAAATGATCATT
+GCGTTGCCGATTTGATGGCCATTCTTCAACACGTACGTCACCTTCTTGCG
+AAGACGTGGACAACGTGGAAGGGTGGCTGTGTAGACGTGAAGCTGGAATT
+CGATGAGATCCGAACGATGGGATGATGGTGTCTTCCAGATGCGTAGTTGA
+CCTTCTCGATTCAGTGCGAGCGCTTGTTTCGCAGATTTTGGACGTTTTGT
+GATGCCGTCTGAAAAACAGAAAAAAAATTAAGTTTGGAGCATCTTGAATT
+TGCCTTTTTTACTTTCGGAACGTCCCACTTTTGCTGATTTTTCGTGTTTT
+TTTTTCTGGAATTTTGGAATTACAGGGAATATCTCTCCAAACCAATTACA
+GGGAATATCTCTCCAAACTGGCCGTCGCAGGAAGACTTCACTTTTAAATT
+GTTTTACCTGTAGGCACAAAAGCAAAAGAGGAGAGCCTACATCTTTGTAT
+CTTCGATAAATTCGTTAAAAGTTCTTTTGTCTTTATTCATTTTTCAAATT
+ATTTTCCAATGTTTTAAAAACATTTTTTCTAAACTTTACAGTAATTTGGG
+CTATTTTCACTATTTTTCAACTTTTTGACGCGTTTTTAATTCTTCATTTC
+AACCTCATTTTGTCCAAACTTTCTCAAATTTCCACATAATATGGCCGATT
+TTCATGAAATTTTCATAATTTACACCAATATATTCAATTTTTAACCTCAT
+TTTTTTCACAGAAATTCCCAACATTTTCACATATTTTTCATGACAAATTT
+GAATTATTTCAATGTTTTCCAAACTTACGAGGATTGGTGCTAGTATTCTC
+TGACCACGGAACCAGTCCATCACACGTCAAATTTCTTGCATCAACCTCGA
+GCCCATCAATAAAGAAAACGAATGCGGCTTTGCCAGTTGTGGCTGGCGGA
+AGGGCCGGTACTCGATTGTTGAGGCATCCGAGGGACTCACTGCAAAAAAA
+TCATCGTTTTTTCTAGAAATGGATCGATGTTTGTGTAACTTTATCGATTT
+GCTAGAATATTATCGATTATTCCGAAAAAAAATTTTAAAACAACAACTGT
+ATTTCTATTTTTATTTTTTTAAAGATAGACTTCCAGATCATATTTTTTTT
+GAAAATTTATTTAAAAAATTATCGATTTCTCTAGGAAAAATATCGGCTAT
+TCTCGAAACTTGTGGATTTCCCTAGAGATTTATCGATTTCTGAAAAAATT
+ATCGAATTTTCTAGAAATTTTGCAAATTTTTTCATAAAATTATCGATTTT
+TCTGAAATATATCGACTTTTCGCCCAAAAAGTACGTACATCAATGAAGGC
+TTATTGACAAGAAAGTGTAATTGTCGATTCCTATCATTCCAGAACTCCAT
+ATCCAACAGCTGAAGATACAAACTACCATCATCGGCGGCTTGTGCTGGCA
+CAGCAAACGGGCATTCTTTCTCGCATTCCGACATATCCGACACATCATTA
+TCGATATCATGTATCTGCGTTGGCTGGAAAAATGGATCCTACACGCGTTG
+AGCACACACTTTGTGAGCTCTGCGAGAGCTCAATGAGAACCTACCGGTCG
+TTTTGTGGCTCGTTTCGCGAATCGTTTCAAATATCCGCCATGCATTCGTG
+GTAGCTCGCCTTCCTGATTATAGTCGTACATGATGAGCGCATGGCTCACC
+ACGAGCCGTGATTCGGTTTCCATCATGTAATAGATTTTTTTGCGTAGTCG
+TGGCTCGCGTGGATTGATGGAATACAGGAATACCAAGTGGAATGGGCACG
+TTTTGTAGTCCATGTTGTCTTTGGTCTGTGAGGGGTTTTGGATATTATTA
+CGGGAGGCATAAAATTCTGAGAATGCGTATTGCACAGCATATAGACCAGA
+TCCGTAAATCAACACAAGCCCTACAGTAGTTATTTAATAAATTACTGTAG
+TTTTTGCTGCGAGATATTTTGCGCGTCAAATGTGTTGCGAAATACGAATT
+CTCAGAATTTTTTGTTCCTAAGAACAGCTCGTCAATTTTTTTTTCAGTTT
+TTCAGGGTTATTCAAAAAAAACCTGTTTTTAAAGCTTCTAGGTCTCATAT
+TTAAAAAGTTTTGAGAATTTAATACATTTTTTTTAATAGAAATTTGGCAA
+TTTTTTCATCACCTCATCGTCGATTATTCTTTTTGAAAAATTTTCGATTT
+TTATGGGAATATATTTATTTTCCAAGAAGATTAACTTTTTTTCAAGAAAT
+CTGAAAATTTATCAATTTTTCAAAAGAAATTAATGAATTTTATCAAAAAA
+AGAATAACTTTTCCAGAAAATATTTTTTTTTCTTAAAAATTAAAAAAAAA
+TTGTTAAATCGCTTTTTGTGTCAATTTTTCAAAAAAAAAAAAGAGGCATC
+GAGAATATCCCATTTTTTTCGAAAAAAATTTTTTGGTTATTTTTCTTTTT
+TTAGATAAAATGTATATACTTTTTTAAAAATGTTTTTTCACCAACAAATT
+TTGATATTAAAAAGTTGGAATTTTATGACTAAATTATGGAAAACTTTTTC
+GATTTTTAGAAAATCGGAAAATTTTGAAAGTGGGCGTCGTCAAAAAATTT
+AATTTTTTAAGAAATTATAGAAAATATGCTGATTTTGGTATTTTTGGAGA
+GCGTCGATTTCCATCGGATTTTTTTGGTTGTTTTCCCTGGGATCCATGTA
+ACACCTGAAACTGTGATCCCAGCTCATCACAAATCACTCCGACTTTGCGA
+ACTTTCGTCCGATAGCACGTCGGATTCTGTGCATTTCCATTATGAGACCA
+TGGCGAGAAGTCGTCACGATTGATGTCGTGTGGAAAGATGGCTGTCCCGG
+CGACGAAGAATGCGTACGCACGAGAATTACGAACAATTGGTGGGTGTCCC
+GGCTTCGCGTAGTTCAGCAGACCACGTTCTTCGCTGGAAAAATGATGATT
+ATATCGAAACATTCGAGGAAAATGGATAGAAAAAACGAAAAATTCAATTT
+TTATCAAAGTTCGTTTATGTTGATGAAAACATTATTACGGGAACACAAAA
+TTCTGAGAATGCGTATTGTGCAAAGTATCTCGTAGCGAAAACTACAGTTA
+TTCTTCAAATGACTACTGTACCTATTGTGTCGATTTACGGAAATAATTTA
+TAAATCGATAAAACAGTAGTTATTTTTAGAATTACTGTAGTCCTCGCCAC
+GAGATATTTTGCGCGTCAAATATGATGCACAATACGCATTCTCCAAATTT
+TGTGTTCCGTAATAAAAAATAAAGTTGTTAGATGAATATTCAGGGTCTCA
+ACAAAATTTAATCTGTGTTTTCAGTTTTCATGTTTTTAGAGTGGAAAACG
+TTTTTTTTTCAGAAAACAGTCAGAAATGTAGATTTTGTTCCATATTTCAA
+AAAATCATTTAAAAAATATAGAACATTTTTTTGAAAAATCAAATTTCTCC
+AGAGTGTAGTACGCCATTAAAGGTCTCGTCACGATTTTGTTTGTTTTCAA
+TTTTTAAGTTTTTGAAGTAGAAAATTATTTTTTTTAGGAAAATTTTTCGT
+CGATTTCGTTGAAAATTCGCTAATAAACGGGGATTAAAAAAAACGAAATT
+TTCCAATTTTTCGAAAAAAAAAATCGAAAAATTCCTCCCAAACTTACACA
+ACATTGGTATTAGCAATCCACTCCAACACGGCCTCAAACGTGCTGGCGAC
+CCTCTTATGTCGAACAGTCAAGTAGATATGTCCCGTTTCCAATTGCCGGG
+GATTCTCAAAATAGGGCGCCGGGTTCTCCTGCTGAGTAAGCGGATCATCG
+TCAAACTCCAAATCGTAGCCATTGTTGAGCACATCCTCTTGAGACATATC
+CAACAAATCATCGTCTAGCAGATGTCCCTGAGCGTCTTGAGCAATCGAAA
+CATCTTGCATTAGCTGATGTTGCTGCTGCTGGTGCTGATCGTGTTGAAGC
+TGGATCTGATCTAGGGAATCATTGTGATGTCCGATGACTTCTTCTTCCAC
+AACTTCCAAATCTTCTACATCTATAAATTGTTCTTCATCATTCGGTGCAG
+CAGATGATGTAGATGGATCTTGTGATGTATCAATCTTCTTCTGATCGTCG
+ATCCATTTCGATCCTCCAACACCTCGTCCAGGTGTTCCAGGTGGTTTAAC
+ATACGGACACGGAACCGGACCATCTCTCACATATTCATAGATATAACACA
+CATTTCCGATCGTAATCGTATTGTTGCGTTGAATATAAATGAGACGCTTC
+CGAAGACGGGGACATCTCGCCAGGACGGACATTGTTTCGACGAGACACAA
+CTGTGACGAGTGCCAGCCGCCAGCCGTGTCTTTTGCCATTTGGAACTGGC
+CGTTGTCGTCTTGGACGATGGCTCGGCGAGTTGAGCGGACGCGGGGTGAC
+GGACCTTCCGAGGCAGCTGAAATTAATGAAACTACGGCACTCTGTACATC
+TCCGGAGGCACCACGTTTTCAAGATCTACCAAAACAAGATCTACTATTTG
+GAGATCTACGAAAACAAAATCTACGTTTTCAAGAAATGGTACCATGCTAA
+TTGCAGTTTTCGCAGTTTTCTCGAAGAACAACAAATCAACAATGTTGACC
+GCCCAGTGTGCTCCGATGTCGCGTGTTGTTTAGCGTTTAGAAAAATCTTT
+TTTGAAAGAAAAACTTCAGGAGAACGATAAACAACGCACGATGAGTAATA
+TGGAAGAATTTTTGTTTCGTTTTTCTTTGAGAAAACTGCGAAAAAGTGCT
+AGATCCTGAAAACGTATATCTTGTTTTGGTAGATCTTATTTTCGTAGATC
+TTGTTTTTGAACAGATCTCGAAAACGTGATGCCTCAATCTTCTGCAGTTG
+CCGAATTTTCACATTTTTAAACCTTAAAACATATTTTTTCTAAAACTTTT
+CCAAAAATCGATTTCTTCGTTTTCACGATTTTTTTCAGAGAAAATATAGA
+AAATCGAAAATTTGTAAATTTTCGATTGAAAAAATGGAAAAATTACAGGA
+AATTATTGAAGATTTAAACTTGTTTCTAAACAATCGAAAATTATCGTTTT
+TTTTCTTTTGGAAATTTTTTTTTGGATTTTTCCCAAAATGGTGGTTTTTG
+AAATCAAAAAGCGTTAAAAACAAATTTCTTTTAAAATTACCGGAAATTAT
+TTTAGAAAATTTCCGAAAAGTCAATAAATTAAAAAATCGAACAAGAGAAA
+GAGTTATTAAATTAAACAAAAACAATTTCACAAAAGTCGATAACTATTGA
+TTTTTCATCAGAATTTCCTAAAAGTCGATATTTTTAAACCTTCTGATAAA
+TTCTTTTTTTGTTAAAAAAAACTTTCGATTGATTAGAAACACGTTTAAAT
+CTTTAATAACTTCCTGTAATTTTTCCTTTTTTTAATCGAAAATTTACAAT
+TTTAATTTATTCTTTTAAAAAAATCAAAAAACGAAGAAATTGTTCGTTTT
+TTCTGGAAAAATTAATTCTTCGGCTCGAAATTTCGATGATTTCTTTTTAG
+AAAAAAATATATGTAAAAAATTATACAATTTCAAATAAAACACTGTTTTT
+TTTCTTTTGATATTGAAAATAGTAGAAATTTTTCAATAAAAATTCCAATT
+GTTCACTCAAAATTTCAAATTTTCGACAAAAAAACTTACGATTAACAGTC
+CACGGTGACAGTCCATCGCCAGTATGATTAATCTGATTTGCAACAAAATT
+CGCCGGCACAAAGTACACAAAAACGCCGGTTGTCGGAATAAGTGGCGGTA
+GGTACGGTGTTCGGCGATTCAAACAATTCGATTGGCTCAGCAGCTCGGGC
+TCATTCACCAAATATCGGAGGAGAAGCTTCTTGTTGTGTGCCCAACCGAG
+TTTTGCAAGTTTTACGCGAAGAAACATTCCACCACGTGGTCCTTCCACTA
+TCTCGTCTTCGAACTGGGAATTTTTTTTTGATGAATTTGAGAAAAATAGT
+TTAAATCTTTATATTTCAGTTTGAAATCGCCGAATTTCAGTTGTGCACCT
+TCGTGTATATTTACGATATGTTTAATCTTTTTCGGATGCTGATTTCCGAT
+CTTTAACGGTTTTCCTTCATTTTCGTCGGTTTTTTTTGGATATGTGTTTT
+TGAGGTCAATTAATGAACCATTTTATTATCAGAAAACTAGCAAAATGTTC
+AATACTCGACAGAAAATCCATATGCTATATGCTTTTCTCGACTGAAAACC
+GGAAATGTTGCTAGTTTTTGATAATAAAATGTTAAATTAACACATTTTCA
+AAAAAAAAACACTTCTACAAAAACCGACGAAAATTAAAGAAAATCGTTGA
+AAAAACGAAAATCAACACCCGATAAAGATTAAGCATTTCGTAAATATACA
+CGAATTTGGTAAATCGACACATGGCATCTCTAGCGCGAAAATTCGAAATT
+CGTAATTTCCAGCTGAAATATTAAATCAGGGAATTTTTCTGAATATTTCA
+CTTAGATATTCGGAATCAGGGAAAAATTTGGAGTTCTTATAAAAAAATTT
+ACTAAGCAAAGTTTTAGCAATTTAGGTTCTAATAGGCTTTACAAATATCA
+AAAAGTCCCGATTTTTCAAGGATCTATATATATTTTTAGAACCACAGATT
+TTTTGCTGTTTTTCAGCATTCTCGGAAGACCATACCGGTGTGGATCCGGG
+ATCATCCAGATCTAACGAGACGTGCGGATCAGTTGGATCGACCATCGCAT
+GTCTTAAATAGTCGTTTCCGTGCGGAAGATTTACGATTGGTGGAATTTCA
+CCGGGACACGTGTAGTCGTAGAGAATGAGCACGTTTCCATAGATTTGGCC
+ATCGCGGGAGAGGTAGAAAATCTGGAAAAAATTTTTTGAATAGATTTTTT
+CGCCTTTTCTGAAGGATTTTTTTTGAAATTTGAAGGAAGACGGGTTTTTG
+CTTGCATAGACTCAAAATAAACCCTTTAGAAAATTTTTACGTTGGCTCAA
+AATATCGAGAATAAAAACCAATTTTTTTCTAAAATTTCGAAAAAATGGGC
+ATAACGGCGGAAAATGTATTTTTATTTGATTATTGTACCTTTTTCAGTTC
+ATTTTGGAGCATTTTTGGCCCATAGGCTTAAAATTAACCTTAAACATTTA
+AAAAACGTGAAATAAGATATCAAAAAGCCATTATGGCCACTATGACCTAA
+AAAAAATATTTAAAAAAAAACAACTTTTTTTTGAATATTCAAATTTTCTG
+AAACTGATAATAAACCTTTTTTCTCAATCTTAACAGTCTCGGCAGCCACG
+CGCTGTACTCGGTGAGATGAAGTTCGGCGATACGTGGATCTCCTTTGACC
+GATTGGAGCCGTCCGTTGAGACGAGCAACCGGATGACGTCGGACATTCGG
+TTTGATGACTGGATCGTTGAAGTGTTGCTCGCCGCCAGTAGAGCTCCATG
+GCTTCAGATCGTCATTCGAGACGTCTTTTATCGACATGATTTTGGAGCCG
+TCCACGTAGAATGCGAAACAGGCTTTGTGTGGAACAAGTGGTGGGAGACG
+GGGTGGTTTGTCGAGAAGCCAACCTCCTTCGCGACTAAAAATGGGGACCG
+TTGATTTTTGTTTTTTTTTTCTGACCGATTTTTCGGACAATAGCTTGAAA
+TTTTGACAATTTTCTTTATTTTTAGAAGATATTTTTTTCTTATATTTTTT
+TTTCTCTAAAAACTATAGTAAAAAATAGTTCAATTTTTTGTGGTTCTGGC
+GAAAAATGTATTTTTTCGAAAAAAATTTTTTTTTTTCAAAACAAGATATT
+TAGATTTATCACTGAAAATTGCTAATTTCCAGTGCGAAAAATGACTTTTT
+CTGGCTATTTCTGCCTGATTTTTGATATAAATTCCAATTTTCACAATAAA
+ATTGCTGAAATTTTCTCCTTTTTTCACTGTCTCCGTACATCATTGCAATT
+TCGGTCTCGTTGGTGAGCAGCTCAATTATTCGTTCCTTTCTGAGAAGGTA
+GGCCAGGCAGCCTGATATCACTGTGGCGTAGCAATCACCGTTTTCCGTCA
+TTTCAACTTCATCTTCGAACTGCAAAAATTATAGAATTGAAAAAAAAAAA
+CGATAAAATCCGACTTTCTCGATGATTTTTATGATTTTTAACTGAAAAAT
+TGATTTTTCGGCATTTTCTGAAGGATTTTGATTAAAATTTGAAGGTTTTT
+TTTTCTCCCGTAGGCTCAAAAAACGCCCTTTTTATGGCGGCTCAAAGGCA
+AATTTTAAGTAATAATCGAATAAAAAATCATAAATTTACGACCCCTACGG
+CACGGGAAATTGGAGACTTCAGCTAAAACTAACCGTTGATTTTGAATATT
+TTGAGCCAAATTTGGCCAAATAGGCATTAAATGCACTCCAGATGACTAAA
+AACACGTGAAAAAAGCTATTAAAATTAGGTAAATAAGACAAAAACAGAAA
+AAAAAGAACTTGAAGCGAAACTGGAGCCCATTTTTGGAGACAATTCTCAT
+TACAAAATTGGTTTTTTGGGCACATTTTTTAGTCTTTCTAGTTATTTCGA
+ACATTTTCCGAAGAATTCCCATAAAACTTTGAAGCTTTTCCATGTAAGCC
+CCTACCAATTTCACGTGGTACTGCCTTTCAGCAAGAGCTTTACTGATAAC
+TCGTTCTCCTTGAACTCGGAACATTTTCGACGGTGTCGCCGCCGCCGGAT
+TTATAATTTTCATCGCCTTCTTCTCCTTATCCCCATCGTCGATAGACCCA
+TCGGTATCCATTGGCTTGCGTGTTCGGACACGTCGCTGTTTGCTGGGCCT
+GGAAAATTTCGATTTTAAAGATTTTTTAAATAAAAAATCCCCCACAAATT
+CATTTCCAAATCCGGTGGTTGCCCATCCATAAACCCGTCGTCCTCCTCCT
+CATCATCACCGAACGGGTCCATTTGTATGCGATCCTCGTCTCGATATCGG
+GAAAGGTTCAGAATTGGCGGCTCATCCTCTACGATGACCTCCGTCTCTGC
+GTGGAGCATCGAGTCGTCGCCGGCGAAGATGGGCTCTCCGAGCTCTCCGG
+CGGTGAGCTCCTCCAAATGTGGCGCTGGCTTTCTCTTTTTCGCGTTTCGA
+ACCGTACTTTCCTCCGTCCTGGAGCGTTTTGGAGCTGCGATCGAGCTTGT
+TGATGCAGAGGCGAGCGCTTCTTCCTTTGGGATGCCCAACTCGTAGTCTT
+CATTGTTGTAGAGCACGGATTTCCGAGCATTTCGACGTGGACGAGATTTT
+GTGGCTGGATCCTGGGGCTCTGCGGCAGGCTCTGGATTTTGCTGGGGCTC
+TTCGGCCGGCTCTGGATTTTGCTGGGGCTCTGTTGGATTTTGCACAAGCT
+CTTGATCAACTTCTTCCTGATTTTCTGCCAATTCTCCCGAATTTTCAGGA
+TTCTCGGACATTTTTCTGCAATTTAATAATTGAAAATAAGAATAATTAAC
+GGGGTGGAAAATTAAAAATTAAACAAGCATTAAAATAAATTTGAAAAAGT
+CCTGATTTGTAGTCCGCAACGCACGCACGCAAGCATACACCAGAACAACT
+AAGAGAGACGGGAGGAGAGATGGAGAATTTGAAAGAGACGGCGAGGCGAC
+GAGAGAGCCGGAGGATTGAGGAAGGACAAACACACAGATGTGGGGTCTTG
+CAGCGCTTTCTCTGCGTCTCTTTTTTCGACATTTTTCAATGGGAAATTTT
+TTTTTGGAGTTTTTCTTTTTTTTTATCGGAAAACTTCAAAAAATTCAAAT
+GGAAACGCTGTACGGACAATGCATAGAATAACACGCAAAAATGCACATTT
+TTAGGCCTTAGGTTACTGTAGTGGTCTCGGCGCGAAAATGCGGATTTTCA
+TTTTGAATTCAAAATAAAAAAACTGGACGTGATTTGGTACAAGCGTTTAG
+TGAAAATGTTTCACAAAATAGGAGATCAATTAGATATATTTATTTATTCA
+TGGAAAATGACTATTTGGAAAAAAATTGCGAAATAAATAAAACTCGATTA
+AAAACAATGTGCATATGTCTTCGTTGCTTTCTTGGCGAGGGTTTCTCGGT
+ATCGAGTTCTACAAGAGACACACATTACGAATAACCAAAATAGTTTAGGT
+AATATACACATTGGGTGGGGGTGGGCCAGAATAATATTGAATAAGGGTGA
+AGAAAAAATATTCAAAATACGTCGCTGAAGTTGGCATACAATCTTGAGTC
+GGATAAATGGTAAGAAAGCAGCACCACTCAACTCAGATCACAATCTTCTG
+AAGAAAAAGGGACGAATGTATAGGTTCGGAGGGGGGGGAGGGGGAAGGGG
+TGGGGATGGAGGCAATTACAAATAAATCTGAAAGAAAGTTACAAATACTA
+CACACCAAAACGGTGAAGACTTGCAAACGCAGTGCTTGCAAGAATTCGAT
+AAAACTCGCGGATGTTAAGAGCGAATCATTTGGATTTCGGGGGCAGTAAA
+TTAAATGGACAAGGCATTTCGAAAAATACACACGTTAGACTGAAAAAAAA
+AAACACGATGTGATTTATGGGATGCAACACTGCTTCTTTGGTGGGTCGGA
+CGCTGGCGAAGGAATGATTGTACCACTGCCACCGCCATATCCTTGTCTGT
+CAGTTCCTACATGCTTGTTGGATACTGATTTGTAGATTTCCGTCAGGATA
+TTAGTGAAAGCTGCTTCAACGTTGGTGCTGTCGAGGGCAGATGTTTCTGA
+AAAAAAAAAATATATAAACGCAATAGATTAGTTTAACTTACCAATAAACG
+ACAATTGATTTCTTTCGGCGTAGATCTTGGCCTCGTCTGTTGGAACTGCA
+CGCAAATGGCGCAAGTCGCTCTTGTTTCCGACCAACATAATCACAATGTT
+CTGATCGGCGTGATCACGAAGCTCCTTCAACCATCGCTCAACATTCTCGT
+ACGTCACATGCTTAGCGATGTCGTAGACTAGGAGAGCTCCGACAGCCCCA
+CGATAGTAAGCGGATGTGATGGCACGGTAACGTTCCTGTCCAGCAGTATC
+CCAAATTTGAGCCTTCACTGTCTTGCCTTCTACCTACAAAAATAATAATT
+TGAATCATAAGTGTATTCTAATGAAGTTCCTCACCGAGATGCTTCTCGTG
+GCAAACTCGACTCCGATTGTTGATTTTGATTCCAAGTTGAACTCATTTCT
+TGTGAAACGAGACAGGAGATTCGACTTTCCGACGCCTGAGTCTCCAATCA
+GAACAACTGAAACAATTTTTCGTTTGGGAATTGAAAAATGAAAAACAAAA
+TTACCCTTGAACAAGTAGTCGTATTCATCGTCACGAGAGCCCATCTTTAC
+TGCTGAGCTGTAAAATGATAAAGCTTGTTTGAAAGTTGTGTATATATTGG
+GACGATTGTAAAAAAGAAAAAGGGCATTGGTCACATGATTCATCAGCCGG
+GCGCAATGTTTTGTTGTAAAATCGATATTAAAAGAACGAGACACTGTTTT
+ATCGGCGGAGAATATTTTTATGTTCTGTTCCCGACACAAACGCGGAGTCA
+GGAACCGGTTGTCTATCTCGACGGGGATTGAAAAAATATAAGTGAACTTG
+ATTTAAGAATGATTCAAAGTATATGGAGTTGGGAGTTTTATATTGAATTT
+TATCAATATATGAGGGTGGTTAGTCAGAAGAAAAATGTGAAAATGTATAT
+AGAAGTGTGTTATGAAAGAGTATTTGAGGCTTATCATACCCGAAAAAGGG
+AAGGTGAGCGGCCGAACTTTGTTTGTCGACACGATTTCGAAATAGTTGAA
+CAGGATATTTTTAACAAGGGAAAGCTTTCTCTGGGTGTTCTTTTTTGATA
+ATTTCAGCTAAAAATTGAAAAAAATAATTAGTTTTATGGCTGTGAACATC
+CAGAATAAGCTTTTCCGAACGCGAAATGCGTGTGAAACCCATAAAATCGA
+ACGTAAAACAGGTCAGGCGCACCGGCGCAGCCACGTCGGTCTGAGGGTAC
+GCGACGCTAGCCGCAGCGCAAGCCTCCTCGGGTCTCGGCACGACAACTAC
+CGTACCCCTTTCGCAGCGGCGCAACGGAATCTCAATTTTACATTTTTTTC
+TTTTTGGCCTAACGAATTTTTCCGTTTTTTCAGAGCATTTTTCATTGATT
+TTCTTAAATTTTCATCAGAATAAATTTTAGAACTAATTTCCCGTAATTCT
+GATACGCGTTTTTTATAGTTTTCGTGAAGAAAATGCTGAACATTCGAAAA
+ATACTGAAATAATTTAGTTTTGAAAACTTGCTCCTCTGTTTCAATATCTT
+ATAATTTTCTTTTCTGATTAATATTTTGATTTTCCAGGTAATCAATCGCC
+TATAATGGCTCCAACGTAAGTTTTCTTTATAAATTTATATTAGATTGAAA
+TTTACTTTTAGGCCTGACTTTCAAATACTTCAATTTTGATATTAATTCTT
+GGTTTTTCAGAAAGAAAGTGCCACAGGTTCCAGAAACTGTGCTCAAGCGC
+AGAAAGCAGAGAGCCGATGCCCGCACCAAGGCTGCTCAACACAAGGTGAC
+CGTCGCCGCTGTAAGTTTATTTAACTGTCAGAAAACAGAAAATGCTCTTC
+AAAAGCACTGGTTTTAGGATCCACTATTATCCAAGCCAGCCGTCAAAACT
+GAGCTATAAGAATTATCTTGTTTTTGGGTGAGGTGTATTCAATTCAGAAT
+GCGTCTCAATAACACGATGACAATTCGAAATTTTAAAGTTTAAATTTTCT
+TTTAGGTGTTTGAAAATTAATTTGAACTAATCCTGCATTAAAAATAAAAT
+TTTTTACAGAAGAACAAGGAGAAGAAGACCCAATACTTCAAGCGTGCTGA
+GAAATACGTCCAGGAGTACAGAAACGCCCAAAAGGAAGGACTCAGACTCA
+AGCGCGAGGCTGAGGCCAAGGGAGACTTCTACGTTCCAGCTGAGCACAAG
+GTCGCCTTCGTCGTCAGAATTCGCGGTATCAACCAGCTTCATCCAAAGCC
+AAGAAAGGTGAAATTGTGTTAATGAGTTTTTTAATAACCATTCTTTGTTT
+TCAGGCTCTCCAGATCCTCCGTCTTCGTCAGATCAACAACGGAGTGTTCG
+TCAAGCTGAACAAGGCTACTCTTCCACTTCTCCGTATCATCGAGCCATAC
+GTAGCTTGGGGTTATCCAAACAACAAGACCATCCACGATCTCCTCTACAA
+GCGCGGATACGCCAAGGTTGACGGAAACCGTGTCCCAATCACCGACAACA
+CCATCGTCGAGCAGAGCCTCGGTAATTTGAAAACTTATGCTTTTTAATTC
+TTATTTAATTGTTTTCAGGAAAGTTCAACATCATCTGTCTTGAGGATTTG
+GCCCACGAGATCGCCACCGTCGGACCACACTTCAAGGAGGCCACCAACTT
+CTTGTGGCCCTTCAAGCTCAACAACCCAACTGGAGGATGGACCAAGAAGA
+CCAACCACTTCGTTGAAGGAGGAGACTTCGGAAACAGAGAAGATCAAATC
+AACAACCTTCTCCGAAAAATGGTCTAACTTGTTTGTTGTTCATACCTTCC
+TTCCGGATAAATCGTTATTGTTTGACGTTGTTTAATTATGTGCATAAATA
+ATCATGAAACGTGATCGTCTTGGCTCGACTCATCTCGCATTTCATGAAGC
+GTCTCATCATTCAGATGAATCGTAAAACCGCTTTGCTGACTACTCTCCCG
+AGAACAGTCACTGTTCCCTACTATGCTCCATCCTGTTTATTTCTAGAAAC
+TTTTCTTCGGAGCAAGCTAATTCCCTATGAAGTGAGAGCATTTAGGTTAA
+TAAACATAGTCCAGATTTAAATCCAGACAACGCAATGTTCTCTCTACAAT
+GTACTCCCTCGTGAGCACCTATACCCATTGATTGATGTCGATGGGTATTT
+CTTCAAAAATTTGATGGAAGGACTTGATTATCTGCTCGCCAAATATGGAA
+AAGTTGGCTTAAAACTAGAATTTTAGAAAAAGCTTAAATATTCTTCCAGT
+CTCTGGACTCGGGCCTGACTCCAAAAGAGCGAGCACAGGCTCTCGCATTG
+AGCGCTTTGCTCGACGAGCTTACTTGGATGCTCGCCTACTCGCGAGGCCA
+AGATTTCACGTGGCTCCGCGATGATCGTAAGATTATCGAAGACTTCGGGC
+TTGTTCAGCTCTATTTTTGGAGGAATTGGATTGTACCGCAGATGCAGAAA
+CGGGTAGATTATTGATATTTTATGGAAAAATCGATAAAATATTGATTTTT
+TACTGAAAAAATTGATCAAAAATCGATTTTTTTTTCCTCGGAAAATCTGT
+AAATTAGTAGTTTTTTGTTGAAACAATCGATAAAATTCTGGTTTTTCAGA
+AGCAAAATCGATATATTAGGCCAAAATCACCAAAAATTATCAATTTTCCT
+ATAAAATTTACCATTTTTGGCTAGATTATCGATTTTTAAGGCAAGAAAGT
+CGATATTTCACAATTTTTTATTGATTTTTTTGGCTTTCCAGCGCGCAAAC
+TGTGCCAAGATCTAAATTTTCCGAAATTTTCATTTCAGACACGCCGCCGA
+GTGCGAGGCTACGGAATATCCGGAAAATCGGCGAGAAAGGAGGTCGCCTG
+CCGAACTGAAGCAATGTTGGAGGCATTGGCCTCACTTTTGGCCTCGAATA
+AATACTTTTTCGATGTCAATGAACCGTCTTGGGTAGGTGGCAGCCAAAAA
+ACTCGGCCAAAACTCGGCCTTTCAGCTCGACTGCAAGGCGTTCGCCGTGC
+TGGCTCAATTCAAATATACACCACTGCAGAACGAGGCCCGCGTAAAACAA
+TTCATGAAGGACCGAACTCCAAATTTGGTGGGTGGCCTTGAGTTTTCTAG
+GCCACGAGATTTGAAAAATTCTATAATTAGGGCATGTGGTTTCAGATGAC
+ATTTGTGACGCGCATGAAAGAGGAATTCTGGTCGGATTGGTGCACCACGT
+CGGAGGATTGAATTTCGTGGAAAATGCTAATTTGTTTAATGTAATATGAT
+TTTGCTTCGTAGATTTTAACCTATGCTCGAATAAAATTTATATTCTAATT
+TTAAAAAAATTTCAAAACAAAAAATTTCTTACGTGACAATTAAAGGGTAT
+TACAATATGGGCATAAAAAATGTATTCCCTAATTTTCGAACTTGTTCAGT
+CTTGGTTGCCCAGGTAATTTTTTTGCAGTTCTTGTTTGGGACTCGGAGCG
+ATTTTGCGCAGATGCATCATATTTGACGCGCAGAGTTTTAATTGAGGTTT
+GAGCTTGAATTGAGTTTGAATTGAATTTTAATTAAATAAAGCGAATTCTA
+GAATAAAATGATGTGTTTATTGCGAAATAGATCGTGAACCTACAAAACAA
+CAGACTTTACGCGCAAATTTCCGAAATTTTCCAGAAAAACCAGTCAGAAT
+TTCAAATGATACTTGTTCCTCTTCTATTTCTTCTCCCAATTTTGTTGTGC
+GGTGGGAAAAAGAAAAAAGCGAACAAAAATGTGAAAGAGGCGTCGAAAGT
+GAACTCACTGGTTCCACCGTCGACCTCTACGGACCCGCTGAAGACTAAAG
+AGAAGGAGATGAAAAAAGAAGAAGCTCCGGGAGCACCAGACGCCCCGACT
+AAGCCGAAAAGTCCTCCGAAACCAGTGGTCCAGGACACGAAACTTGCTGA
+AGTGCTGCCTGAAAGTGAGAAGGAAGACGAAATGAAGAATGGTATTCAGT
+TGCCGAATCCGCCGAAAAATTTGGTGGGTCTCACGGCGATTTGAGTGTTT
+TATCGATTTTCTATGAAATAATTGATTTTTTCTAAAATTATTGAGATCTA
+GATTTGCGAGTTTTCTGAATTTTCTAATATATCGATTTTTCAGAAATGCG
+AAAGTGAAATTGCTCCAAAGGAAAAGCCGGCGGCTGACGAAAAGAAGGAC
+GAGAAAAAAGATGAAAGCAAGAAGGATAAGAAGGAAGAGAAAAAGGAGGA
+GAAAAAAAAGGAAAATGACGAAATTATGTGAAAAATTCGATAAATTGGTT
+CTTGAAGATTATTGATTTTTCATTGTCGATTTTTCAGAATTCCTCGAAAT
+TTATTTGCGCGTCATATATGGTGCATTGAGTCCATAGAGACTTCAAAGTT
+CACGCGCAAATGCAGACATTTTTGCACGCGCTGCGGTGAAATTCCTCTTG
+GCGAATTCAAATATTTTTTCCCGCCTTTTTTGAAAATTTTCGAGGCGTTG
+GTCGAGCTGAATACACGTGAAGTTTAGACTGAATGTCAAATCACAAATAC
+ATCACATTTGACGCGCAAAAAATTCGTTTTGAAAATTTGCGCGTCAAATA
+GGGTGCATTGAGTACGCGGAGCCAATACATCACACTTGCTTTTCGTGGAA
+AATGGAGCGAAATTTGATTTTTTGATTTAAATATTACGGGAACAGAAAAT
+TCTGAGAATGCGTATTGTGCAACATAATTGACGCGCAAAATATCTCGTAG
+CGAAAACTACAGTAATTCTTTAAATGACTACAGTAGCGCTTGTGTCGATT
+TACGGGCTTGATTTTTTTTCCATTTTCTTCAGTTTTTCTGACATTATTGT
+GTTTTATTTTAATATTTTTACCGATTAATAAATGATTTCCGTAAATCGAC
+ACAAACGCTACAGTAGTCATTTAAAGAATTACTGTAGTTTTCGCTGCGAG
+ATATTTTGCGCGTCAAATATGTTGTGCAATACGCATTCTCAGAATTTTGT
+GGCCACGTAATATTTGCGTTAAATAAAAATCAAAAAATTAAAAAAAAAAA
+AACATTTCAGAAATTTTCAAAAATTTTTTGAAAAATTGACGCACAAAGTC
+TCCTGTTTCCCTTTTCCCCAAAGTTTTAAACTAATAAAACTTTTTTAATT
+GTCGAATCCGACCAGTTATTTAATACGAGACAAAACGGAAACAAAGATTC
+CAATTTCCGATTACGGTCAGCTCAACACTTTCGCTCAAGGAATTCTCTAC
+GCTTAGATTTTGATCTTAATGGAAAACTGGTAGAACTTGGTATAAAACTA
+TCCAAAAAACTGGCAGAAAGAGTAGTCTTTCCGAAGAAATGAAGTCCCTA
+ATCGAGGAAGATGACTTGGAAGTCGGCAGATTCCGCCGCAACGCGTTTTC
+CGCCGTCGCCCTCTCCACCTCCTGTATTCTGGCGATTGTGGTGTTAACAC
+CAATTGCCTATCAGGCAATTCAGAGAATTCACTCAAATTTGCTTAACGAT
+GCCCATTTTTGTCAGGTAATTTTTTTAAAAAATTTAGAAATTTTGATTTG
+GAAATATTCAAATAAAAAAAAAGTTTTTCGAAATTTATTTTCAATCGTTT
+GAGATTTTGACATACATTCCAAAAATTCCTACTCTTCGCAATTTTTTAGT
+CAACTCAAACTCAAAACCTTAAAAAAAAACCGCAAACCTGTCATGGCGCA
+TCGATGTTATCCCTACGCTAAATGTTCTGTTTTCGAAGGTTACTTTTTTC
+CAATTTTTATCACCAAGGAAAATGTATACACAAAAATATATAGAATTTGA
+CGTGCAAATTGGCAAAAAACTAAACTTGCGCGTAAAATCACTGCATTGCC
+TCTGCGGACTCAACACACCAGATTTGAAATTTCAGGAACTTATCGATTTT
+TGTAAAATTTTGCAGCATGGCGCATCGATTAAATATTAAAAAAAAATTGA
+AAATTATCGATTTTTTTGAACACGAACAATTTGTGGAAAATATGAAATAA
+AAAAAAACATGGTGCATCGAAAAACTTACAGGCTCGAAACCGTGACCTCT
+GGACAGAAACAATGAAGATGGCTCGGAGCCGCGGCCGGGACGAGGAGCTC
+GTGGCCCGAACCAAGCGAGCGGTTAAAGGCACATGGCTCTTCGGACAGTA
+TATTCCAGACCGATCAAGCAGAAATCGACGACAGCAATACGCCGAGGCCG
+CTGGCGGAGGCGGTGGAGCACCACATGCCGAGTGTAGACGGGGTCCACCG
+GGACCACCGGGTGATGGTAGGTTTTTAGATTTGCGAGGCAATTGTGGTGT
+ATTGGTTTAATTTTACAGACGGGGTCGACGGAACGGACGGAAAAGACGGT
+GCACCTGGAACCGATGGAAAAGACGGTCAGGTACCACAAGGACCAGCCGA
+CGGAGGTTATCAAGAGGGACCATCTGATGCAGTTGAAGCATGCACACGTG
+AATGCCCACCAGGACCGCCTGGACCAACTGGAGCGCCCGGAGACAAAGGA
+TCTCGAGGCTACCCTGGAGAATCTGGAGAGCCAGGCACCCCGGGAAGCGC
+CGGACCGAAAGGAAATGCTGGACCGTAAGTGGAACTAAAGAATCGATAGT
+TTTCGGTAAAAAATCAATCATTTTAGGAAAAAAATCGATAATTTTCATTT
+TCATTTTTCTCCATTAAATTATGTTAACTTTCTAGAGCTGGACCACCAGG
+ACCACCCGGATATCCAGGACGTCCTGGAGAAACCGGAGATCACGGAAAGA
+CGATCGCCGGAGAGGCGCCACCTGGACCACCAGGACGACAAGGAGAAATG
+GGTCCACAAGGACCACCGGGACCACCAGGGCCACGTGGAAAGGACGGAGC
+CGGTGGAGAGAAGGGTGCTCCGGGAGATCAAGGTAATCCGGGACCATATG
+GAAAACCTGGGCAACCGGGAGCTCCAGGACCCGATGGCTCTGCTGGTGAG
+AAGGGAGGATGCGATCATTGCCCACCGCCAAGAACTCCACCTGGTTATTA
+AAGATTCTTCGATTGATATTTTATTTTATTTTCATGACGTTATTCATTTT
+GTCATTCGGTTTTCTTTTGTTGCAATATGATAATAAATCAGATTCTCTTG
+CCAGTAGTTCCAAGTGCCCCAACATATTTTTGAGTCCTTTATGTAGATCC
+CTCTCCTCGAAAGCTGGATGATTTAATAAATCTTTCAGAAAAATCGAAAA
+TTTTAGAAAAAAAAACATCAAAATTTTTGACAAACTGCATAATCAGTCAA
+TATTCTAAAAAAAAATACGATCGCACAAAAATAAACAACGACGCAACGAC
+ACTCCGCGGTTACTAAGCTCCGCCCACGATTTCATTTGCACTGCGTTGAG
+TCGGCCGTATTGTTATTCAAACATGAATGAATATACTGGTGAAGTTTAAA
+AAATTGGGTGTTTAGTTTTGAAGAAAATAATTTTTTTGGAATTTTGAATA
+AAGCACAATTGGCAGCTGAAACTGGACTTTCAGACAAATTTTGAACGGTG
+GTTGTTGATGCTTTGAGTTTATATTGTTATTCAAACATGTATGAACTTGT
+AAAGTGCTTGTAAAACTTGTAAGTTGCTTGTTCGCTCATTCTGAAATAAA
+ATTTAAATTAAATAAAAGTTCACGTGATACAAAAAAGCCAACTTATTGAT
+TGAAATCGATAAAATCGATAAGAAATTCATTCATTTAATAGTTTTTAACA
+AACAACAAATGCGATCAAAAAGTTCGGAAGGTGATTTACAACCAGAGGAC
+ACCCAATCCAGAGAAGATAAAGAGACGACTGCTACGTATAGTGAGGATAC
+AAAGCCAGGTAAATACAGTAGTCCTACCTTAAAATTACAGTAACCCAGCT
+GACTAAATATCATAATAAAACTTGCAAAAAAATGATGTAAAATCTTAGTT
+TTTAGTCTTTTGAACTGGTAGAAACTGTGTTAGCGCCACTTTTTGACTCT
+AAATAGAAAAATTTCCCATTTTAAAAGAGTTGTATTATGATACACTGCGT
+GGCGTGTAAAATACCAAAAAATAAGCGCGGTTTTTTTTTTCGTAAAATCA
+CAGGGAAAAATCCGAAATCGGAACTCCAATCAGCCGCCAACATCCCACGG
+GCCCAATAACTTCTGGGTTTTGTTTCAACAATCTCATTTACTCCAATTCC
+AGAAACCCAAAAGGAGAGAAACGCGGCACTGGACAATCTTGCCAAGACCC
+CAATCCAGTTAGTCGTCCAACCAACTCCTCTCACACCAGCCATCACGCCA
+TGCGAAGCACCACCACCACCACCTCCACCAAAACCCTCTAGCGATAATAA
+CAACTCGAAACGATTGAAAGTGAAAGATCAACTGATTGAAGTGCCCAGCG
+ATGAAGTAGGCCGAGTTGAGAATAATATAGACAATTTCCCGTTCTATCAT
+GGATTCATGGGAAGGAACGAGTGTGAGGCGATGTTGAGCAATCATGGAGA
+CTTTTTGATTCGAATGACGGAAATTGGGAAGAGGGTCGCCTATGTGATTA
+GTATCAAGTGGAAGTATCAAAATATTCATGTTCTAGTGAAACGGACCAAG
+ACGGTGAGAGTTGTTTGGTATTATCATTTAGTTTCGTTTCAAATCAGACC
+GAGATACATACAAATATTGAAGTTCAAATTTAGAACATGTTGCATCGCAA
+TGTGTTCATTGTGCTCCCTGAAGCATTATGCGGACATCACGAATTACATA
+AATTATTTTAACCAATGGTGGGCGGCAAATTGACAAATTGCCGATTTGCC
+GAATTTGCCAAAAATTTTCGGAAAATTGTATTTTTGCACATTTTTTTTAA
+ATTTCAAAATTTCAAATTTTATCGGCAAAATTGTATGCATCCTATGAATA
+TTTCTACATCTGTTTCGAAAAGTAAGCAAATTATATGAAAATATCTAAAG
+AAAAGGGGAAAAAATTCGAAAAGGCACAGTTTTCAGTGTTTCCGTCTTAC
+AAAAAAAACCTCGAAAAACTTTCGGCAAATAAGCAAACCGGCAAATTGCC
+GGAAATTATAGTTTCAGGCAAATCGGCAAACCGGCTATTTGCCGAATTTG
+CCGAACGGCAGTAGCCTCTCACCCCTGATTTGAACATGGTGCATTGCATC
+ACCGCTCCTCGACTTGGAAAGTTTATATCGGTAGATATTTGCAGCAGATG
+TAATTTACTGATATTTTCAGAAAAAGCTCTACTGGACCAAAAAGTACGCC
+TTCAAATCCATCTGTGAGCTTATTGCCTATCACAAGCGAAATCACAAGCC
+GATTTATGAGGGCATGACGTTGATCTGTGGCCTGGCACGACATGGATGGC
+AGCTGAACAACGAGCAGGTCACATTGAATAAGAAGTTGGGAGAGGGACAG
+TTTGGAGAAGTGCACAAAGGATCGCTGAAGACATCTGTATTTGCAGCCCC
+GGTCACTGTTGCCGTGAAGACCTTGCACCAGAACCATCTATCCGCCAATG
+AGAAGATCTTGTTCCTAAGAGAGGCCAATGTGATGCTCACCCTGTCTCAT
+GTAAGCTACCTGTTTCAAGTTGAACTAAACTAAAATTAATTTCAGCCAAA
+TGTGATAAAATTCTACGGAGTATGCACCATGAAGGAGCCCATCATGATTG
+TCATGGAGTTTTGCGACGGGAAATCCCTGGAGGACGCTCTACTCTCCAAG
+GAAGAAAAAGTGTCAGCTGAGGACAAGATTCTCTACCTTTTCCACGCCGC
+CTGCGGTATTGATTATTTGCACGGAAAGCAGGTTATTCACAGGGATATTG
+CGGCGAGAAATTGTTTGTTGAATTCCAAAAAGATCGTGAGTTTGTTTTTC
+AAAAATTTCTGAATCTATGTGAATGAAAAAATAAATTTCAGCTGAAAATC
+TCCGACTTTGGATTGTCGGTCAAAGGAGTTGCTATAAAGGAGCGAAAGGG
+AGGATGTCTGCCGGTCAAGTACATGGCTCCGGAGACATTGAAGAAGGGGT
+TGTACAGTACTGCCTCTGATATTTATAGGTGAGCCTACGAGCATACATAG
+ACATTGGTAGTGGCGTCAGCGGTGGCCTAGAAACCTTATCCGCGTCTGAA
+GGTTAATCAACCTCACACAAGTCTCTATGATTTCCAGCTACGGCGCTCTA
+ATGTACGAAGTCTACACGGACGGAAAGACGCCATTCGAAACGTGCGGGCT
+ACGTGGAAATGAGCTCCGAAAAGCGATCATCGGGAAGAGAATCAGCTTGG
+CCGTTGAGGTAGAGCTACCAGTGTTCATTGCCAACATTTTCGAGCAAAGC
+AGGCAGTACGAGACCGAAGATCGCATAAGCTCCAAGCAAATTATTCAGAT
+TTTTAAGGAGGTTTGTGAAGCATTTTATCGGTTTTTTGTTCAAAAAATTA
+GTAATTTTCCAGGAAGTCGGATTCCATGAAATTGAGACAAGTGGGATACT
+GCATAAGCTTGTCAATTCTCTTCCGAGAATTCACAATAAGGAAAGAAAAC
+CCGCGGCGGTGGCAGTGTAATAAATATCTGAAAATCCCCCCACCCCTGAA
+AATATTTGACTGTATTTTTTAAATCAAACACACAACGCACACAAACAGAC
+AGACAGAAAGCCTAAGTACACAGAGAAAATGTTTGAGGTGAGGTGCGAAA
+GGGAGGAGGCTAGAACACCTACTTTACGCCAACAAGTTATGACTTTTTGG
+AATTCAAAATGTCGTTTTTTGCTAGTTCACTGCTTACCTACAAACCTTCC
+TACCTTGTCTGCCTACCTTCCTTCCTATTCTCTTATTGCAAGATCTTTTG
+AATTTTTCTGAAACGTCTGTCTACTTCTGCGTCATTTGCAAACAGGCTGT
+TCTCAGTTTTAGGGGGTGGCAGCACCCACAAAAAAACATTGGAACAGAAA
+TCAGTCGGAGTGATCTACTAGATTAGATAAACATTAGATATCAGTTTGGA
+AAAGTTAAACATTATTAACTCACAATGGATTTTCTTATTGTGTTTCTTGA
+TATAAAGCGTTGAGCGGTATTGATACCATTACAATGCACTAAGCTAAAGG
+CTGTCAGAGCCGAATGAAAAACATGATACATCGAGCATGCGGCAATTGGC
+GTTCGGAAAATCGGCAAATTAAGATTTGCCGGAAATGTTTTGAGGGATTT
+TTTATAAGATTTAAATGTGCCTTTTTGAAATTGTGTCCCGTTTTCTTTAG
+ATATTTTTATAGGATTCGCTCACTTTTCAAAATAGACGTAGGAGAATTCA
+TAGGATGCATACACTTTTGCCGATTGAAATTTAAATTCTGAAATTTCCAA
+TAAAAGTGCATCACCACAATTTGCCGACTTTTGGCAATTGCCGTTTCTCC
+GGCAAATTCGACAAACCGGCAATTTGCCGATTTGTCGATTTGCCAGAAAT
+TTTCAATTCCGGCAATTTTTCGATTTGCCAATTTGCCGAGAATTTCAATT
+CCGTCAATTTGCCATATTGCCGGAAAAAATCGTTTGCCGCCCATCCCTGG
+TTCGAACTCCTAGAATGGTAGAATATGAGTATACTAAAAATAATTTGAAC
+AGAACTGGAACTGGAAGAAAAATTTTTTACCGACGTCTTCTGAGAAAATT
+TCGTGAAAATTGAGTTTTTATCACTTTCTGACTCACAATAAAAAAAATTT
+CCAAAATTTTTTGAATAGTTCTCGATCGTTTCCAAACTGGTCTTCCGACA
+TTCAGGTGCGTGATTGGTAAATATGAGGGAACTGCCATAATCAAATGAAA
+AACACGGTGTATCGTCTGAGAAAACCTTAAACTGTTCCGTTTTAGTAATT
+GGACAAGGATCTGCTGAATCTCGCTACTATAGCAACCGACATCTTGCGGG
+TCCAAAAAAGATTGATCTTGAAAATTTGATCCAAGTTTATTTAATCGCCG
+CCACACACACACTCACAAAAAAATCAATCAAATCACCCATATCAGTTGCG
+CGATTTCTAGTTTCTAGGCGCGAAAATCAAAAGGAGGAGAAGAAGCATTT
+CCGCATTACTCGTGTGTGTGCCGTTTCCGTTTATTTGTCCCTCAGGCTCC
+CCTCTCTGTTTTTTTTGTTTGCGAAAACTGTCTCTCTCTCTCTCTCTCCA
+TCACTTTTCTGTTGCGGAATAGAGGGAGAGAGAGAGAATTTCGGAGGGAA
+AAATACCTGAAATGTGATCCTCTCTCTGTATGTCATTGACTGTTGCGCGA
+GAGCCTTTTCCCGCGCGCGCGAGCCTCCCACCTACCCGTCGACGAGCCTA
+TTTTCTTGTCGGCGGTGCCATTCGGCAATACACGTCCCTCTCTCTTCTTG
+CTCTAGAAACATTCGGATTTTGATTTTTTGATTTTTCATGGTGGATCTGT
+AGGCTTTTTTAGGCCATCTTGGACTTTGTGGTGGCCTAATATATGGTGTA
+TTTTCCAATTTATCATATTTGCTTTAGTATTGTCCGACTTGTAGGCAAAT
+TGCACCATTTTAAGCCAAGTAATAAAGCTTTGAAGTTTGGCTGCCTAGGT
+TTTTCTAGCCACCAAACAATTTTTTTGTTTTCACAGCACACTTTTTTAAA
+GACTGTCATAAGTTTTCAAAATTCTTTGAAAAATTTTACACCGAATTTTG
+AGATCTTTAAGTTTGGTGGCCTAAATTTTTCAAAATTTTCTATGCCACCA
+GACTGAAACGTCCTAACTCTATTTGAATTATCTTTGAAACTATGAAAACT
+ACAAGTTCGACTAAATATGGCTTATCCAATTAAACTCGATTGGTGGCCTA
+GAAAACCAATTTCGATTTATTTCATTTTCTAGGCCACCAATAATCTTGTT
+CGAAAATTACTTTTATTTAATTACAGTGGAGTTTGGAATACTTACTGCCA
+TGGGCTGTAAGATGTTGCTCGCCTAACTTTTTCTATGCCAGCAACCAAAA
+AGTGGTGTTGGTGGCCGACAAACCCAAACTTGGACAATTGCATTTTCTAG
+GCCATCATTTTTTTTAAACTAATCGTTGTTGGTTTAGTCTACTGTAAAAA
+ATCAAATCGATAAGAACATTGGGAGCCAAGCTTTGGAGTTGGTGGCCTAG
+ATTTTTCTAGGTCACTAACTTGAAATGTCTGTAACTCTAAAAAATAATTT
+AGAGATATATAACAGAATTAGTAGGCTAATTTTAGGATGAGAAACTATTT
+AAACAATTGGTGGACTAGAAACTGAATTTTGAAATTTCTAGGCCACCAAT
+TCCAAATAAGCCTATTTCACTCCTGAATTGAGATAAAACGCTGAAATTTT
+GGACATATTAGAATACGCTATATTTGAAAAAATGGAATTGGTGACCTAGA
+AAATATTTTTTTGAAATTTCTGCTCCACCAATTTCAATTATAGCATAACT
+CATTTCATAGTTGTAGGACGGTGATTGAAATTTAGGATAGACAGATTTTA
+AACCAAAACAGATTGATGGCCCTTGAAATTTCTAGGCCACCTCTCCAGAA
+AAAAATCTGAAAATTGTTTTTATTTCTAATTCATTTTCTTCGTCCGTTTT
+TCATCTCTCGAGGATCTTATCCCCTTGTCTTACGTCTCCCACCCGCTGCT
+ATTTGGGCGACCTTCATAACTGTGAAAATTCTCACCATTCTCCCTCTCTC
+GTTTTTGCCCCCCCCCCCCGGTCTCCTATCATTGTTCAAGTACACCTGTT
+GTCCCATAACATCTGCCAACCAATTTTTTCCAATTTTGCCACAATTTTTA
+TTCAAAAAAGTGCATTGCAGCGGCAGGCATGCCTCACTCGTACACACACT
+TGAGCATACAGGAAAAGCGAAAAAATCAGTGATTGTTTGGATTCCTGGCT
+CTTTCTAGGAAAAAAACTCTTCCATTTTTGTAGTGCACATCAAAATGATC
+AAGCTGGTTAATTTTCAAGTGACTCCCAAAAAAATAACTGAGAAAGTTGC
+GTTTTAAAGTTTCTAGGCCATTGTGGGATTTCTAGGTAGGTTTTTGAAAA
+TAGAAGACAGTCTTGCACTAAAGTTTTGATTAGGCTGTTAAATGATTTTT
+GTCAGTACGTTTTTTGGAACTTCGATTTTTGCCAAAAATTCCTTTTTTAG
+TTTTTGTTTCAGTTTTTTGCAAATTTTTATTTCTTCCATATCTTACAACA
+TTTAGAAGGTCTCAAAGTCTCTGATAGCCAAGAATTGACTCTAATGACGT
+TATGAGCTCCGAGACTATTTTAACCTTTTTCCCTTTTAAGCATAAAATAT
+ATAAATATCAAAAATTTAATACAAAAACTTCTCGTTTCGAAACGTTTCGA
+AATCCTCCAGTTAAAAAAAAATTAGATTACGGCATCGGAAAAATTGCGAA
+ACTTTTGAATCTGAGGGATTTTCAATAGAGGGTCCCGCCAGGAATTTGAG
+TTTTTAACAGTACCCTTTCCATCGTCCTTCCCGAAGCCCATTACATCATC
+ATTAATTTTGCGACCTTTCTAAAAGCGGTCATGGGGGGGGGGACATGTGT
+TTGTTGCATATACAGGGACCCCCCGCCACAACCACCGCAACTAGAGATAA
+AGATCTGCTGCACACAGACAGCTGGCACATGGATGGACAGAATGTCTCCT
+TAATTTTACCGCCTATTTCATAATAATAAAAGTAGAACGGGGGGCAGAAA
+AGAGAATGATTGCGAAACCACCTGCTTGGCTGTCAGCGCATAAACTTTTC
+GGAAATTTTGGGTCCCACCACGCTTTTTTCGGTAACAAATTTTGAGATTT
+CTCGATACACCATGATGTCTTTTGGTGGAATTTTGGGTTATCATGGCTAA
+TACAAAGCTTTAACGTGCCTTGAACTTTCGCAATTTGAACTTTTGGCCTT
+TACTTAAAAATTTCGATGGGGCTCTATAAGCCATGTGGTTTCGAACTTTT
+CCTGAAAATTTAGATTTTTGTTCATGCACCATGTTGTTTTTTTTTTGGAA
+TAATTGAGGAATTCCTTACTTTTAAAGTAAAAAGTTTGGTGAGATCCATG
+TGTTTTCATATTATTCAGTTGGTAAATTATACAGATTATTGACTGAAGGT
+TAATTTTTTGTTGGGAAAATAAAAATCGCCAAAATCAATAAAATCGTATT
+TAGAAGTAGGGTTTCCATATAGGCGGTAAAAGGCTTGTCTGCCTGACAAT
+AAGACGACCGCCGCTCGCCTCAATCCGCGGCGGAGGCAGGCAGGGTTCAG
+GTAGGCACTGAAACCGCGCCTGCTTACCATGATGTTCCGTTCTTGTCGAT
+GCACCATGATAATTTTGGGTTACATTTTGAGCCTTTTCGAAAAATTAATG
+GTGGAAAATTTCAAGCTGAATTTTAATATTTATTTTTTTAACCGTATTGT
+GGGACATGCAAATGTCTTTCATTTTGTGTCCCTTCACTCTAACGTCTTCA
+GAATTTTCGAACTTCTCGATGCACCATAATGCTGTTTGGCGATAACTTTA
+GAGTAAGAATGGTAGCGATTTTTGCGATGCACCATGACGTTTTTATCGAT
+TTTCAGAAAAAAAATCACTCCGAGACCCAAATAGTTTCATTCTCGACGCA
+CTATAACGTTTTCGAAGTAAATTTCAAAATTGCTTCTCGGAAAAGTTTTT
+TGAGACCTACATGCACCTTTAATCTTCTTTGGAAACTTTGGAATTTCCGC
+CGAATACTCTCATTTCAGTTGTTCTCGATGCACCATGATGGTATTTTTTT
+CAAATTACTTTTTTTTGATTTTTCCATGAGAGGACCAATATCTGTCTTTA
+TAACGGCGCATTCTGTAACCAAATTTTGAAATTCCACGACATTCTGCTCT
+CATCGATTCAACATGATAATTTTAAAATGAAATTTAGCGATTTTTCGGGA
+AAAAAACAGTTTCGAGATTTTCTAGTTATTGGACACTCTGCACCTTGCTT
+ATTTGGAAATTACATTTTAAACCGACAACCCTTCAAAAACTGCTTTTCGT
+CGATGCACTATGAGTGCATAATTTTGTGTAAATCGTGGTGGGCCTCTAAA
+AAAACCGAAAAAAAAAACGTATAAAACGCAAACAAATTGTTTTTGTTGTA
+ATGTTGACACCAACAGATTCGGCGTGGAATATACGGAAGATCGGATTTCC
+AAAAAAACAACCGCTCTCCTGTTTTCGACGTTCCGCCGCTTTTTATGGGA
+GAAGTAGTATGTACCTTTAAGGGTACTGTAGCCCCTTGAATATTGGCCTA
+AAAGTGAAACTAGTGTTGCCAAAAAAAAACGAGATGACCAGTTTCAATAT
+GTCATTTACATCTACACATTTCTAAAATCTCATTTTAAATTCCATTGTTT
+TCTCGTTTCTTCTGTCCCAAAGTACCGTATCCTCATCCTTCTACCACCTT
+AATTTGCATTTCTTCTTCCTTATTCACTCTTCTTCCCCTGGACGAAAAAT
+GTTGCACGACAACAACAAAAGAGACCCGCCCCCCACCATCGGTTTCTCTG
+AACCTCTAACTGTCCCCGCCCCCTTTTGGGAGCCCACTGTCTTTTCTTTT
+TTTCTTTGGTCGCTGATTATGACGGATCGTTTTTGTCGTTTTTGTATTAC
+AGGAATACAAATTTCCCAAAACGCGTATTGCACAACATATTTGACGTGCA
+AAATATCTAGTAGCGAAAACTATAGTAACTCTTTAAATGACTTTTGTAGC
+ACTGATGCCGATTTAATTAAATTATTTATTAACAGATAAAATATTAAAAG
+AAAACACGACAATTCAAAAAAATTCATTTCGTAAATCGAGCCCGTAAATC
+GACACAAGCGCTACAGTAGTCATTTAAAGAATTACTGTTTTTTCGCTACG
+AGATATTTTGTGCGTCAAATATGTTGCGCAATACGCATTCTTATAATTTT
+GTGTACCCGTAGTATATTTTTGTCTCTCTGATTTCCATTGCAATTTTTTA
+ATTCCATATTTTTTTGGTGACAAATTTCTCCGCTTATCAATTTTTTTTTC
+AACCACATAATTATTAACCCCAAAACATCGCAGATTTTCAGGTAAAATGC
+CAGTCGTGAGCGTTAGACCTTTTTCTATGAGAAATGGTGAGCAATTTTTT
+TGAAGTTTTTTTTTGAAATTTTTAATTTTTCCAGAAGGCTTCTCAAACGG
+GCATAACACGTGGAACGACGCCGAATTTTGGAAACCGTGAGTTTTCGGCA
+AATAAGCTAACAGTCTAAGAAACACGAAAAAAAATCCAATTTTCTTTTCA
+AAATTCGTGATTTTCGGATGATTTTTGAACTTTTTGATTAATGTTCCCAC
+TGAAAATCCTCCAAATCTCTAAAAATCCGCTTCTAAAAAAGCCTCAAATG
+GCCTTGCGAGAATAGACGGAATGTTCAAGGATGACTGGTATAAAATCGGC
+AAACGTGTTGCCATTCAAACAGAATATCTCGAAATTTCGCCTTCCTTTTT
+TTTAAGTGGGTCGGATATTTAACATACAGAAGAGAATAGGGAGAGAAAAG
+AGGGAAAAGAGGGGAAAAGTCTTCTTGGAAACAACCTCGAACCGCAATTA
+AGTTTTTGCCTCACCCTTCAATTTTCGTGAGAAAGTTAAAAATCCAAATT
+TTTTTCTCCTTTTTTAAAAAAAGATTTCCTCCTCAAAAATTCAAAGGATC
+GAATTTTTTGTTACACGCCTGCCTCCTTTTTATTACCCTTGTTCTTGATC
+GCAACCTCTTTTCTAGATTACTTGAAAAAATGCGCTATTTTTTTTCCTTT
+TTCAACAGAGTCAATTTCAAAGGTGCTGTGGAAAAAGTTTCGGTTTTTTT
+TTGCAAAAATAATCGAAATTTGTTCGTTTATACTGCTTAAAAAATGACCA
+AAATTTCAAGTAATTCATTCGAAAAATCGATTTTTTTGAAATATACAAAA
+ATTTTCAATTTTTCATATCTGAAAACACAATTTTTTCGATTTTTCATTTT
+TCTTGGAAAAAACACAAAAAAAAACTGTATTTAATTTCCCACTTAATACT
+ACGATATCCAAGCCCCGCCTCCGCGTATTGTACGTGAACACGGCGGCCCA
+AAATTACACACTATCTCACACACGTTAAATGAGTGATACCGTACTCTCTC
+TGTTTTTTCTTTCATTTTTTCGGCGCCGAAAATTTTCAATTTTTGGTGGT
+TCTTTTGGCGGGATTTTTCGGATTTTTGTCGCGTTCACACACACACACCA
+GTTGGTGTTGCCTGTCGTCACCCACCCGCCCCACTCTTTGTCCGTGTACT
+GCTTTGCCATTTGTGCGCGCGTACCGCTGCCCGTCTGTCTTTCTCATCAT
+ATGCGCCTCGTTTTGTCGCTTTTTCTCCATTTGCCCTTCCTACATGGGTA
+CCTGCGGTTTTCATCGAAAATATCCTTAAAAATTCCGAAAAACCTCTATT
+TTTCGATTTTTGAATCGATTTTCGCCCAAACATAACCATTTTTCAGAATG
+AAGGAAGAACAAATCGCCTATAAATTGCCAGGGGCTTGGTATTACGAGGA
+GGACACTGCCTCGTGCTCTCCAGTCAGCGATCCGGAGGATATTGCGCAGT
+TTCTCAACTACAGAACGTCGATAGGCGTGCAAAATGTCACAGAGTCCGTG
+GAAGTTCCGACGTCGGAGCATGTCGCCGAGATTGTTGGTCGTCAAGGTAA
+AAATTGCCTTTTTAGTCAAATCTACAGTTTCCACAAATTTTCAGGCTGCA
+AAATTAAGGCACTGCGCGCCAAGACCAACACCTACATCAAGACACCGGTT
+CGCGGAGAAGATCCAATTTTCGTGGTCACCGGACGCCTGGAGGACGTGAA
+CGAGGCGAAACGAGAGATCGACTGCGCCGCCGAGCACTTCACACAGATCC
+GTGCGTCGAGAAGACATACACAAGGTAGGTGACCGTAGGCAGCCGGTTCC
+TGAGCGCCTTGTTCAGTTGTTCCAGGAGCCCATGCACCTGGACAGATCAC
+GAGCTATGTCAGAGTTCCGTTAAGAGTTGTCGGACTCGTCGTCGGACCGA
+AAGGAGCGACTATCAAGCGAATTCAACAGGACACCCACACGTACATCATT
+ACGCCGAGCCGAGAAAGGGAGCCCGTTTTTGAGGTAATTTTGTTGGAGAG
+CATAGAGTTTTGGAGCAAAATTCTCAGCAATTTCATGCTTTTTAACAAAA
+ACAGAGAAGTTTCTAGTTTCGGCTTAGAAAATACTGAAAATCGGCTTTTC
+CATGGCATATATCGTGCTGAAAATCTACTTTTGACTGAAAAATTCAAGTT
+TATGACTAAGAAAAGTTAGATAATTAGACCATGCTATTATTTCATAATAT
+TGGTCCAATTTTTGTTGCTTTGCTGAAAATTAACAAAATTTAAAAATCGG
+CGGGGTTTCTGAAATATTTCTGTATAAAAACCGATTTCAACTCCAATTTT
+CCTCGATTTTTACATATAAGTAATCTAGAAAAATTGTAAAATGGGGAGAA
+TTCATAAGAAAATCGGCTGTTTTGTAGCAAAGTTTGTAAATATATCATTC
+TGAAAGTCTCAGCGATAACCGTGATTCTAGAAAACCTCATCAGGATTTGA
+TTTCTGCGACACACTTCTCTCGAGTTTTACATAGAAGTTGTTCATTACAA
+ATTTCTATTTTTAAGGTCCCCATTACCATTGTCAATCTTTCATTCCGATT
+ATTTGTTTTTCCTCGTCACTGCAAGAAGGGGAGCCTAATGCCTAGACAGA
+GACAGAAAACACATGTGTGTTTGTAAGTGTCTGGTGTGATATACCCAATT
+CTTTTCGGCCGTCTCTTGTTTTCTTCCTGACACCGAGTTTCGAGCGATTT
+TCGAGGTCGTACAGTTGTGAATTGGCTGCCACTGCTGTGGCAAACAAACA
+AAAACAATCAAACTTGTGCGGAATTGATATTCTAAAGAGAATAAAGAGCA
+ACCATGGGCGCCGAAACGAGCAGCGGAAGGGCTTGTGACCTCTTGGTGTG
+AATTTTAAACGGTTTCCTTCCATCCGAAATGCTAAAAATTCCTCGGGAGC
+CGTTTAGGGTCTTCACTGAGAGATGATGATTAGAATCTTTTAATTTGGTA
+GAATTCCCCCCGCGGGACCGATTAATGTTGCATGTCGTCTTCTTCTTCTT
+GGCAGCAAAATATCATTGTTGATGAGATATCTCAGTTTGATGCTCAATGA
+CGCCTTGAGAAACATCCAGCACACAGTAGATTAGTCGAATTACCGATGGA
+TGGGGCCGCCCGGGTTTTTGGAGCCAAGAGTCACGCGATGGGGAGTCCAC
+ATACACACGCACCAACTCTTTCATTCCATCTAACAGGGTAGTAGGGTGAA
+GAAAAGGGGGGGGATCGCGATGACAAAGAGACTCAATTAATTAAATGACC
+GGGGCGGGCGCCAAATTGCACATATGCTTGGTTTTATTGCACCGTTGGCT
+CAGGGAGAGCAACATTTTGTGGCAGCACCAGGGGTACTTCAAAATGACGA
+ACAAAGGTCGTTGTTGTTTCTATAGGAAGGCTTCCGAACTTTTGAACAGT
+AATCAGATCATATTAGGGTTATGTAATTGACGGTTTTGACCGTATGTGTC
+TATAGATGCGTGTGTGTGTGTGTGTGTGGCGACATAAATTACCGTATCCG
+CATGGCCTTTTTCCTCCTTCCTCACAATGGTAATTATCATCCCCCACTAC
+TCTGGGTCGCCGGACGAACTGTGAATGTGTTGACAGTGCGGGCCCACTAG
+TACATGACATCTTGCCCCGGTGCGGTGCGCTCATCGTTATTCCTCCCAAT
+TTAGTTGTCCGTTTGACACAAATGCCTCCGGTACCCTGGACGAGACAAGG
+AGGTGATGGATTTGCCAGGCGGGGAAGGAATTACATGATGTTTGGGAGAA
+TATGAGGGAAAGGTACAGAAGCTTCACCTCGGATATTATATGCGTTCTAA
+AAAGACCAATTGTCGTTTTTGTTCGTGGCTCAAATGAATAATTGGTATGG
+AAATATAGAAAAATGTCCGACTAGTTTGGTAATAGAATTGTTTCGTTTTG
+AACATTTCAAAAATACCTCAAATAGTGCACTTGAGATCTTTGTTGAATTT
+TCAAAGGTTTTATTTTCAGATAAATTGAGCATTTTCCATACTTATAAAAT
+CAATTTTTGGTTCAAAAACTTCTAATTTTCTCACCGAAAAAGTTCTCACA
+AGACAGTGACAGAGGTCGCGTGTCGTTTTGATATCCATCTCGATAATCAG
+AGATTGTGATCTATGCCTCAATGACACAGTTCCGCGAAGGAGTCCGAGAA
+AAACGTACAAAATTGGGGAAAAATATTGGAAATAACATTTATTGAAAAAT
+TAAAAAAAAAACATAAACTATTTAAATTCACAAAAATTCGGAAGCATATT
+TCCTATAATGAAAACAAAAAATTCTGAAAATGTGTACTGCACAACATATT
+TGACGCGCATAATCTCTTGTAGCAAAAACTACAGTAATTCATAAAATTGA
+CTACTGTAGCGCTTGTTTTGAGTTACGTGCTCTACGAAATGAATTTAAAT
+AATTTATCGATGGAAAAATAATTTTAAGCAGAAAATGAGAAAATAATATG
+AAGAAACAAAAAGAAATTCGAGTTACGTGCTCTAAGAAATGAATTTAAAA
+AATTTATCGATGGAAAAATATTTTTAAGAAGAAAATGAGAAAATAATATG
+AAGAAACGAAAAGAAATTCATTCGAAAATCGAGCGCGTAAATCCAGAGCT
+ACAGTAATCAGTGAAAGAATTACTGTAGTTTTCGCTACTAGATATTTAGT
+GCGTCAAATATGTTGCGCAATACACATTTCTGGAATTTTGTGTTTCCGTA
+ATAAAATAAGTTTTTTGCGAGAACTACAAAAATATAACTATTTCTATTCC
+AGGTGACCGGCCTCCCACATAACGTCGAGGCTGCCCGCAAGGAGATCGAG
+ACGCACATCTTCCAGCGAACCGGAAATCTTCCAGAAACCGACAATGACTT
+TGCCGGACAGTTGGCCGGTGTCTCGTTGATGGTGCAGAAGCAGCAACAGG
+CTCAACAACAAATGCAGGAGGCTCAGCAACAATCGATGTTCTATCGAAGA
+GCATTCGGCAACAGTAATCCGTTCAATCAGAAGGAGATGTCGTCGTCGCC
+ATTCGGAATGGAGAGCTCGTTGGGATTGGACGCGTTGCTCCGCAGTTTCC
+CATCGATGCGTAGTTCGTTGACTCCGGAATCTCTTTCCGGTACTGGACTG
+TCTTCTCGTCCATCGTTGGGAGGAGGACAATCGGCGAAACAAGATCTGCC
+AACCTACGACTACTGGGGAACCAACAACTCGCTTAATGATATTATGGAGA
+ACGGTAAGCTTTTTTTGCGAATTTTAATAAGAATTTTAAATGACAAATAA
+GGATTTTTCAGAAATTCTCAGCCGCAAGTACGATGCCCTGTCCGCATGGT
+CGTCGATGGGATTGGAGAAACGCGAGGAATCCCCAACCAATGGGTATATA
+TTTTTGAAGGAATTTTATAAATTTTTGAAATAAAACTAAAAATTGCAATT
+TTCCTTCAAAGTTCTAAATTTTTGAAAGAAAATTTGATTTTCCGCTAAAA
+AATTTAAAAAAAAAACAAGTTTTCGTGTTTTCCACTCGGAACCTGACGGC
+TTCTTATCAATTTTTTAAATAAAAAATAACGTTTCTAAAACTCAGAATGT
+TTAAAAAATTTCACATTAAAAAATTATTTTTCCGAAATCTTGAACCTATC
+CGTTTTTGAAAATAAAAAAGAGTAAAATCGTAGTTTTCTCTATAAAAATT
+ATAATTTTCATTTGAAATTCAAAAATTTTTAAATAAAATTGGATTTTGTC
+CGTCAGAAATCTATAAAAAGAAAATTTTTTTTGAACAATAAAAGAAAAAT
+TGTAATTTTCTTTTGAACTTCAAAAAAATATGTTTTTTTTCACATGCAAA
+AAATTGATTTTTTCAAAACCTCGTTTTTGAGAGAAAAAGGTGAAATTCCA
+ATTTTAAGAGGTAAAGTTAAATTTATTTATTTTATGAGAAAAACTTGAAA
+TTTAAAGGAAAATTACTGAAATTTACAATTTATCATACATATTTTTTAAT
+TTCGACATATCTCGAAATATCAAGTCGTAAATTTTTTCCACAAAAGTGTG
+ATATTCTCTTTAAAAACTAGAAAATTTCAATTGTAAATTTATGAAAAATC
+AAATTTTTTGCAGGCTCATGTCCTCCCTCAAAGGAACATCCGCCGGCTTC
+GGTCTTCTCAGCACAATCTGGTCTGGCGGAAACATGAATCTGAGCCCAGG
+ATCGTTGGCTTCAGCATCTGCCTCGCCGACTTCATCGACCTGCGATCACA
+ACGATCATACTCTCGTGCCGATCAATGGATAAGCTGTGGATCCATTCATC
+ATTCCATTACTATCGTGTAGACTCTCATCTAGCAAAAACCCATCCTCAAC
+GAGTTCCAAATTCATCTTTCCATTCTTTAAAAGACTCTTTTTCCCATTTT
+CTACTTTGTTCATCGGTGTACGAGTCCCTCCATTCCCATTTTCTCACCTC
+TTTACTACATTACTAGAACACACAAAAATCACCATCATTCTCACCCCAAA
+ATCCTAGACAAAAAAAACGAAAAAAATCACATATATTTATATATAACTAT
+TATTATTTGTTATTCATATTTTTGAAATATCTATATTATATATATTTATA
+TATGTAACCCATGCAGTCCCCCAATATATATTCCTACAGTAGGTTTTTTT
+GGAAAATCTGTAACTTTCTCTATTATTCTTTTTTGCATTATGATAGGACG
+ACCAACTCATGTTTTAAACAAAAATTATATATATTATAAGGATTTCCTCT
+TTTCTCTCTATCTCTCACCTAGTGTTTAACTCCCAATTTTCCCCCTCTCT
+ACTACGCACAACTAACGGAGAATTGAGAGGCCTTTTATATTTATAGCACC
+TCTTTATAATTAAAAACTCGAGTGATCCCCACCTCACCCATCAAATTTAT
+CGTATTTTGTAAAAGTTCTGATATATTCCACAGATTTTGGTGTATGTGAA
+TGAAGCGATTCGTGTCGTCTCTCCATATTCTGGTATCCATAGCAACTCCC
+CGAGCTTTTGGCTCACTCGCGCACGCCCTATACTATACCTTTACTATTAT
+TAAATGCACTCAACAAATCCTATCCTGCGTCAATTGGCCGATCAATTGTC
+CGAATTGCCACAATATGCACCATTGCGGGTAATAATAGCACAATAGTTGA
+ATATATTAATAATTCAAAAATATTTATTATATTTTGAGGTGTCCCATTGT
+TTCAGACATATATCCGCGCGACGATAAGTGCCACGTTGGGGGAAACGCCA
+AAGAAAACGAGTAGGGATTTGACGTATAGAGGTGAAATTTTTAGAAAATT
+TGAAATTTTCTGAAAAAAAAAGGATTTTTCTTTTATGAAAAATGCTCTTT
+TCGCCAAAAAAATCACAATTTTCGACTTAAAAACTTCAAAATTTTTTCAG
+GAACACACAATTCAAAATACAAAATATCTCGTAGCAAAAACTACAGTAAT
+TCTTTAAATGACTACTGTAGAGCTTGTGTCGATTTACGGGCTCAATTTTA
+AAATTAGATAAAAATGAGAAAATAAAGACACGAAGAAACGAATGAAAGTG
+TAATATCGAAAATATTCGAAAATAAATAAATTTCAAAAATCGAGTCCGTA
+AATCGACACAAGAGCTACAGTAGTCATTTAAAGAATTACTGTAGTTTTCG
+TTACAAGATATTTTGCGCGTCAAATATATTGTGCAATATGCATTTTCAGA
+ATTTTGTGTTTCCGTAATAGGTAAAATGTCAGAAAATCAAGGATTCAGTG
+CAACCCCGCGTTCTACGGGTATTTTGGCCACGGCCACTTTTTGCAAAACT
+GCAAAATAGGCGTTGTTATTTCATTTTCTGAAAAAAACATTGAAAATTAT
+TATCGAGAAAGTACGATCTGACAAATTTCTCATAATTTATTTTTGATCTA
+CCTGTTGAACTTTACTCCGCCCCCAATCTTGTTGCCGTTGTTATTTTGTT
+GTAGCTGTCTTGTCGAAGGACGGGGAGGAGCCTAGTCAACAAGGTAGATA
+AAAAATATATTATGAGAAATTTGTGCGATCGTATTTTTTCGATTATATAT
+ATATATATATCTTCATGTAATTCTCATGAAATCTTGAAAAAAAACGCGAC
+ACATGGTATTACCACGCCCACTTTTTATAATTTGAGCGCGTGCAATTTTT
+TGTCGATAACATAGTTTCTATTTAAACAAAAAACATCGTGCGCCCACATT
+GAAGAAAATCCTATAATTGGGCGTGGCCTTAACTCTGAAAATTTACAGAA
+CGTGTCACCCATAGCATGATTGCCGATTGGCTCGAGCAGAATGGATATCC
+AATATCATCTCAAGTCTTGAAAACAGAAATGTCTGGAAACTACATGGAGA
+GTGCAGAAAAACACGTGGAAAATGGGGAAAAAATCGATAATCTATTGCGA
+AGTCAGCTGAAAATCGATATTCGCGATGGCACCGGTGACGATTTTGAACG
+AAAATCGATAAAATCGATTGGCGCCGGCCGCCCGTTTGCAAAAATTAATA
+TGGTCGATAAACAGCGAGCACCGTTGAAAATTACACCGCTTAGTGATGAG
+GAATTTCGAAAAACGATGCGGAAACGGATGGAAATGGAGAGGGAACGAGT
+GAGTTGCGTTAAATAATTTTTTTTTGAAATATTTAACAAAAGTCGACAAG
+GCGATTTTTTAAAATCGATGTTTCGCGACTTTTATTCAAAAGAAAAATTT
+CAATGCCCTAAATCACTCAAATGATGATTAAAAAAGTATTTGCGCGCGCG
+CGTAAAATTTAGTGCCAGCGTATGACACTATGTGGTGCAAACTTCACTCC
+GGGTCCGACACTTTTTGGATTTTGCGCATCGCTATAAAGATTTCAGATCG
+CGGCGTGAGAGCGGCGTTTGCGGCGCCGACATGAGAGTCCTACTTTCCTA
+CTTTTCTTGGCAAAAAAATCGATCGATTTTTCAGCTCGCACGTCTATCCA
+ACCAGGCAGAAGACGATTCCGACGATTCATCGTCCTCCTCCGACTCTTCC
+ACGTCATCCGCGTCGTCATCTTCCGAGGAGAAGTTGACTTTTTCGGATAT
+CTTGGGGAAACCCACAGCAGCTGGCGCGGAGAAAATGATCGAACTAAGCC
+AAATTCCCAACGCATGGGGTCCGTCAAAATCCGCGTTAGTCACTGATGAC
+GTGGCAAGCACTTCTGACCCACTTCCGGCGATTTTCAACGCACATCTTCC
+GCCGCTCTCCATGGGACGACCACCGCTGACAAAAAGCGCGAAAAGTCGGG
+AAATCGACGCCATTTTCGGCTCGGATAACGTGGATTATGATTTAGAGGAT
+TTCGAGCAGGATGGCGTGGCGAAGAAAAAGTCTATACTGCCTATGGAGAA
+AAAGAAGGAGGAAGCGAAACCAAAGGAACAGGAGCTAGTGGAGCCGTTGG
+TCTTGTCAGAAGGTAACTTTGAACTTGCACCATGCAAAAATTTCGAAAAA
+TTATGCACGTGGTCACTGGCTGTCCTTTTGCATAAGCTTGAAGCAAACGC
+GCCTCATTGAGAATTCACGTTTGCGCCAACTCTCGCTATCCATTGGGCGT
+GAGAGACGCAGATACTACTTTTTTCTCTGAACGTGAAAAACGCAAAGAAT
+AACCGTTTTGCCGTCTGCATCTCTTCTTTCACACGCTATTTTGGCTGTGG
+ACGAGGAATTCTCCTCTTCCAGGATTTTCTAGGCCATTTTCTCATATTTC
+TCAAGTTTTCTCGTCCGCGAGAAAACGTGAATTTTGAGACAGCCAGCGAG
+CACGTGATTATGCAACTCTCCTAAAAATCGATCATTGTTCCTGTAGCTTA
+TAATTTTAAAGGCGCATATTCCGCTTGCGGAGCAAAAGTAAAAAAAAAAC
+ATGCCTCTACATACAAATCGATGAATTTCCTGAAAAATCAATAATAAAAA
+ATTTTCAGGAGAATCAATCGACGAGCTTGAAGATTTCGACACCGGTCTAC
+TATCTTCCGGAGGATCCGATTATTCTTTTTAAAATTTTCTTCTTTTAAAA
+AATTTCTTTTGAAATAAATAAATTCTCACCTAGGAATTTCAACAATTCAA
+CTTGAAAAAAGTTCGCGCAAACTACGAACAAATGTGTGTCGAGCGGGCGG
+AGCCACTGAGAAAGAGGAGCAAAATGTACACAAAACCATATTTGAGTGTA
+ATTTTTCAAAGTTTGGCGCCGATTTTCTGTGAGAGATGAGTTTTCTCAAT
+TTATATTTGGTTATTTTTATTTTAGTTCTTACTGGTAAATTTCTGGGTAA
+GTCCTGATGACTTTGAAAACGAAAAAAACTCTTTCATTGATGCTAGTGCG
+ATTGCTAGGAAAGCAACTTTTCAGTTACCAAGAAAAAGTCCAAGGCCATA
+GGGATTAGCTGCGTGGCATAACAACTCATCCATCCTCGCAGATGCAAATC
+CGCTCTATTGGCAAATAACATGGAAGAGTATAAACATTTTCTCTTCCACA
+CGGAAACCTAGTCCCCTTGGGGAGCGGTAGTGCCCACAACCCCGCATGTT
+TACCAAACTACACAGACAGCGCTATTGTCTGCAAGTGGCAAAAAATGGCC
+GCCGAAAATTTTTACAATGTAAATAATTTTCAAAGTGTTACTATTTGCAC
+CTTTTTGGCAAAAATTCCATAAGTAAGAAATTTGATGGAAGAGATGCGAG
+GTGCGGGGAGTCTGAAAATGGCTGCATGGCCTGTATGTGACCTGTGTATG
+TGGCCTAAAGGTCTAGTTACCCCTAGAAATCAAAGTTCAGTTCAGCAAAG
+AGACTTTATTTTCAGCACTCCAACAAGAGGCAGAAACTCAACGGTACGAC
+GGATGGTACAACAACCTGGCGAACAGTGAATGGGGTTCTGCTGGTAGGTT
+TTTTTGGAAGAGAAATGACGTCACACTGACCTACTCCTTCAGGAAGTCGG
+CTGCATAGAGATGCACGTTCCTACTACTCAGACGGTGTATATTCAGTGAA
+TAACTCACTTCCGTCCGCCCGTGAACTCTCCGATATACTATTTAAAGGAG
+AGTCCGGTATTCCTAATACAAGAGGATGCACCACTTTATTGGCATTTTTC
+AGTTTGTATTTTTTTAATACTTATAGTAGCCAATGTTTGTAGGTCAAGTA
+GTTGCTTATGAAATAATGCAATCAAATGGAGTATCCTGTCCACTAGAGAC
+ACTTAAAATTCAAGTACCCCTATGTGATAATGTATTTGATAACGAATGCG
+AGGGGAAAACTACAATCCCATTTTACCGTGCAAAATACGACAAAGCAACT
+GGAAATGGTCTTAACTCGCCTCGAGAACAAATCAATGAACGGACTTCATG
+GATTGATGGATCATTCATCTATGGTACCACCCAGCCATGGGTGTCCGCAT
+TAAGATCTTTTAAACAAGGACGGTTAGCTGAAGGTGTACCTGGATATCCA
+CCACTTAACAACCCACATATTCCATTGAATAACCCCGCTCCGCCACAAGT
+ACATCGATTGATGAGTCCAGATAGATTATTTAGTGAGTTCATTGTTCTAT
+AGAAAAGTATAAATATTTAAAATTGAAGTGTTGGGAGACTCGCGTGTGAA
+TGAGAATCCTGGTCTTCTTTCATTTGGTCTGATCCTCTTCCGTTGGCATA
+ACTACAATGCAAATCAAATCTATCGAGAACATCCTGACTGGACAGACGAG
+CAAATCTTCCAGGCAGCACGTCGTTTGGTGATTGCATCTATGCAGAAGAT
+TATTGCATATGACTTTGTTCCAGGACTTCTAGGTTACTCAACTATCATTT
+AATAGCTTAAACTCAGTGTTTCTTTTAAGGTGAAGACGTTCGTTTGTCAA
+ACTACACCAAATACATGCCACATGTTCCACCTGGAATCTCGCATGCTTTT
+GGAGCAGCCGCCTTCAGGTTCCCTCACTCAATTGTGCCACCAGCAATGCT
+TCTGAGAAAACGAGGAAATAAATGTGAATTCCGGACGGAAGTTGGTGGAT
+ATCCTGCATTGAGATTGTGCCAGAATTGGTGGAATGCACAGGATATTGTG
+AAGGAGTACAGTGTGGATGAGATTATTCTTGGTTAGTTCATACTTGAGTG
+GTTATATAATAAAGATTGTAATTTCAGGAATGGCAAGCCAGATAGCTGAA
+CGAGATGATAACATAGTAGTCGAAGATCTTCGTGATTACATCTTCGGACC
+AATGCATTTCTCTCGTTTGGATGTTGTTGCTTCATCAATAATGAGAGGAA
+GGGACAATGGAGTACCACCGTATAATGAATTGAGAAGAACATTCGGACTT
+GCACCAAAGACATGGGAGACAATGAATGAAGATTTCTACAAGAAGCATAC
+TGCAAAAGTGGAAAAGTTGAAAGAGTTGTATGGAGGCAATATTTTATATC
+TGGATGCTTATGTTGGAGGGTAAGCGTTTTTTATAAATTAAGTTAGAGAT
+CCTCCAATATACCCTCATAACATATTGTATCAGTTTACTTCATCAATAAT
+TCAGCTTGAACCATTTAGAATGCTGGAAGGAGGTGAAAATGGGCCTGGAG
+AGATGTTCAAAGAAATCATAAAGGATCAGTTCACCCGTATTCGAGATGGA
+GATCGATTCTGGTTTGAGAATAAACTAAATAGATTATTCACTGATGAAGA
+AGTTCAAATGATTCATAGTATTACACTTCGTGATATTATCAAAGCAACAA
+CCGATATCGATGAGACGATGCTTCAGAAGGATGTGAGTTTATTGTAAACA
+CCCGTTGGTGATGATCGAGTAAGTTAATAGCATGTTTCATTCCAGTCATT
+GATTGATATTTTGTCATGAATTGTTATATAACAATATATGTATGTATTAT
+ATTACTCATGTCTCAATATTGCATTTAATTTCCAGGTATTTTTCTTCAAA
+GAAGGTGATCCATGCCCCCAGCCGTTCCAAGTGAATACCATTGGACTTGA
+GCCTTGTGCTCCACTTATTCAATCCACCTACTGGGATGATAACGATACTA
+CTTATATCTACACTCTAATTGGTTTGGCGTGTATTCCTTTAAGTCAGTCT
+TTATTTCAATCTAAATGACTACCGATAGAGACTCAGCGATTATAGAGTTG
+ATCAAGCTAAGAACTTTCAGTTTGCTATAGTATCGGTCATTATATGGTTG
+AACGACGTATCCGAATAGGTCATAACAGTGCTTGTGACAGCTTGACTACT
+GACTTTTCAACAGAAAGTCCCAAAGTTAATGTCTACAAAGTGAATGGTTC
+GTTATTTTTTCATACTTGATTTTTATTTAAATTATACGGTGAATCTGTTA
+CAGCTTTGGAATGGCTTCAAGAAGAGTACATACGGCAAGTTCGGATAGAA
+ATAGAGAATACCACGTTGACAGTGAAGAAGCCACGTGGTGGAATCCTTCG
+AAAAATTCGTTTTGAAACTGGACAGAAGATTGAGGTATTCCACTCTATAC
+CGAATCCATCAGCAATGCACGGACCATTTGTACTTTTGTCTCAAAAGAAT
+AATCATCATTTGGTGATAAGATTGTCGTCTGATAGAGATTTATCTAAATT
+TTTGGATCAAATTAGACAGGCGGCTAGTGGAATCAATGCAGAGGTTATCA
+TAAAGGATGAGGAGAATTCTGTGAGTTTACTTCAAGAAATACGTCGAATC
+TGGAAATTATTTCAGATTCTCTTGTCCCAAGCAATCACAAAAGAACGCCG
+TCAAGACCGACTGGACCTGTTCTTCCGTGAAGCCTACGCAAAAGCATTCA
+ATGATAGTGAACTTCAAGATTCGGAAACTTCATTTGACTCATCGAATGAT
+GATATATTAAATGAGACAATATCTCGTGAGGAATTGGCAAGTGCAATGGG
+AATGAAAGCTAATAATGAGTTTGTGAAGAGAATGTTCGCGATGACTGCAA
+AACATAATGAGGATTCGCTCAGTTTCAATGAGTTTTTGACAGTATTGAGG
+GAGTTTGTTAATGGTGAGTATGATTTACTAAAGTTCTGATCACAAAAACT
+ACACGTGAATGAATGTTCCAGTCCGTTTTACACTAGGTTCGGTAAATATG
+TATAATGTTATAGTGACTGTTACATGTTGAAGCAGTAGTCTTCTTTTCTT
+TGAATGGCAACAAAAAGGCTCCCTCATTATTTAAGCTGTATTTCACTGCG
+AATAACGGCTTAATGTGCTATTTAAACATTCGGGTCTATTAGTCTTTTAG
+TATATTGTCGCGCATACTAAGGCTCGCTTTAATAATCAGTTTGAAACGCG
+AATTTGATGGTGTTAAATACGATTTTAATTTGGGAATTGTTCACAATTAG
+ATGCTATCTTGACTAATAATAATTAAATACAGAAACAAAAAACTTTTAAT
+GGACAAAAATCACTCCGAAACTACCCAAATCGGCATTAGGTTAATGTCTT
+TGATTACTCACCTTCTTTCCTAATTTCCAGCTCCTCAAAAGCAAAAACTG
+CAAACTCTATTCAAAATGTGTGATTTGGAGGGAAAGAACAAGGTACTCCG
+AAAGGATCTCGCAGAACTCGTCAAGTCCCTCAATCAAACCGCCGGAGTTC
+ACATTACCGAAAGTGTGCAGCTTCGATTATTCAATGACGTGCTGCACAAG
+TCTGGTATACATCCCTGTTTAGTATGCCAAGTATTATAAGAAGTTTCAGG
+AGTAAGTGACGATGCGGAGTACTTGACTTGTAATAATTTCGACGCATTGT
+TCTCGGAGATCTCTGACGTCCAGCCGATCGGTCTGCCATTTAATAGGAAG
+AATTATAACTCACATATCAAGGAGTATGTTGTTGAATTCAAATCCGCAAG
+TAAATACAAACTTCAGGCCATCATGCCACACCTCATTCCCAATAGTGGAC
+CACTCTACTCCTGCTCCACTTTCTCTGATTCAGAGAATTTGTGCATTCCT
+GGAAACCTATCGCCAACACGTCTTCATCATCTTCTGCTTTGTCGCCATTA
+ACATTGTCCTTTTTTTCGAACTTTTCTGGCGTAAGTTTACTGTTTAGTTC
+GGTTTTCAAAAGCAATATTCAATTAAGATTCCCGCTACCTAAACGAAGAT
+CGAGACCTCCGTCGGGTGATGGGTGCCGGGATCGCTATCACTCTCTCTTC
+TGCGGGAGCCTTGTCATTTTGCATGGCGTTGATATTGCTCACAGTTTGTA
+GAAATATTATAACACTGCTTCGAGAGACAGTTATTGCGCAGTATATTCCA
+TTTGACTCGGCTATCGCGTTCCATAAGGTAAGAGCCTCTCTCTTGGCCTA
+GCGCTGTAAATAAAACTGCCAAATTTTTAAACTCCATCAATTTCAGATCG
+TCGCATTATTCACCCTATTCTGGTCTACCCTTCACACCATCGGCCATTGT
+GTTAACTTTTATCACGTTGGAACTCAAAGCGACCGTGGACTTGCTTGTCT
+CTTCCAGGAAACATTTTTCGGGTAAGCCCCACCTACTCGGTAGATCTCTC
+AGTAGATTGAACGTTGGCTTGCTTTCAGATCTGACGTCGTGCCTACCCTA
+AGCTATTGGTTCTATGGAACAATTACTGGGTTGACGGGAATTGGATTAGT
+TATTGTTATGAGTATCATTTATGTGTTCGCATTGCCAAAGTTCACTAGAA
+GAGCATATCACGCGTTCCGGCTGACTCATCTTTTGAATATTGGGTTTTAT
+GCACTCACTATTCTTCACGGACTTCCTTCACTTTTTGGGGTAAGGCTTAA
+TTTAATTTGATTCATTTACGCTCTTTTTACGCTCTTGACGTCAATATTTG
+TTACAGTCTCCCAAATTTGGCTACTACGTTGTTGGACCCATTGTCCTTTT
+TGTAATCGATCGTATAATTGGGTTGATGCAATATTACAAGTCGTTGGATA
+TTGCCCATGCAGAAATCCTTCCATCAGATATTATATACATCGAGTACCGT
+CGTCCAAGAGAATTTGAATATAAATCAGGACAATGGATTACTGTATCATC
+ACCATCTATATCATGTACCTTTAATGAATCTCACGCATTCTCGATTGCCT
+CAAGTCCACAGGATGAGAATATGAAGTTGTATATAAAAGCAGTTGGACCA
+TGGACATGGAAGTTGAGAAGTGAATTGATAAGATCATTGAATACAGGGTC
+ACCATTCCCATTAATTCATATGAAAGGACCATATGGTGATGGTAATCAGG
+AATGGATGAATTATGAAGTTGCAATAATGGTTGGAGCAGGAATCGGAGTG
+ACTCCATATGCATCCACGCTTGTTGATCTTGTACAAAAAACATCAAGTGA
+CTCGTTTCATAGAGTTCGATGTCGTAAAGTATATTTCCTATGGGTGTGTT
+CGAGTCACAAGAACTTTGAATGGTTTGTGGATATGCTGAAAAATGTTGAA
+AATCAAGCAAAGCCGGGAATCCTGGAGACACACATATTCGTCACTCAGAT
+GTTCCATAAGTTTGATTTAAGAACTACTATGCTTGTGAGTTTTTTATGCG
+TTTTTGGTTTTTTAGTGGTATAACTCTAAAACTAAATGTTTGGAGAAAAA
+GGCTTAACTAATAAAATGTTGCTCATAACTTTTTCTATGCAATAAAATAT
+GTTTCAAAATTTCATCCGAGATCTCACAAGTCCAAATTTGATTATTTTTC
+TTAAAACGAGTATATTTCAAGACCGAAAAGTTTTCTTGAAAAAATGGTAT
+ATTTTTTGCACATAATCATTTTTTCATAAAGTGCTCTGCAAATCAGAAAT
+TAAAGTTCGAACAGTCTTATAGTTAGTACCGTGACATTTATTGTAACTTA
+AAAAAAAAAATTACGCGACATAGAAACGCTCGATTATCTGAAAAACCAAA
+TTGGATTTTGATTCTAGTTAATTTATTTTCAAAAATAAACATATTTTGTG
+ATAATTGTAAACTAAAAACTATACCTGAATATTTTTATAAATTTTATGTG
+GTTTTTGGTTTCAGGATTAAAACAATGGTAAAATACTACCCTAACGGCTT
+ACCCAAGGCTCAGAAAATTGTAGTTAGTCTCAACAAATTAATACATATCA
+TTTCTTATTTGCAGTACATTTGCGAGAAGCACTTCCGTGCCACCAACTCA
+GGCATATCAATGTTCACTGGCCTACACGCTAAGAATCATTTCGGACGGCC
+CAACTTCAAAGCTTTCTTCCAATTTATTCAGAGTGAACATAAGGAGGTTA
+GTTTCATGGTTTTAACCTCTAAATAAAGCAAATTTGCAGCAATCCGAAAT
+TGGAGTGTTCAGTTGTGGACCTGTAAACTTAAATGAAAGTATAGCTGAAG
+GATGTGCAGATGCCAATCGACAACGAGATGCTCCGTCATTTGCACACCGC
+TTTGAAACTTTCTAATCTTTCTACTGTTACTTACTATGAAAATCATAAAA
+ATTAAGACGCTTCATGAATAAAACATTGAGAAAAAAAACCTGAAATAAAG
+AATTTTCACATTTGTCCAGGTAGTATATATCCCCAATACAAACATTTTGA
+GACGCGAACCTTCCCAAATAATCATCAGACATTGTTCTGTAATTAGGCAA
+AAAACCAGCCCCCTAGCCTCCTCCCTCACCACAAATAAAACCAATTCCCC
+CATTTCCCCCCAGTTCATTCACCAACAATGAGTTTGTTCAAAGTATACAC
+CTCGTTTTCTTTGTTTTTCTCCGTTCTATTCCTTCTCGTCGCTTTTATTG
+TGATCTATGACATTTTCGATGAAATTCGCGAATTTCAAGAAGTAATCGAA
+AAAGATGCCAGGAAGTTTGAGGTAAGGCAATATGTGGTGCAGCAATAATT
+TCCGCATTTTTCGTAGATCATACCGTTATGGGACAGTCTGACACCACGTG
+ATAAAATAGTATACTAAGTATTACAAGCAAGGTTGAAACGAAAATGAAAT
+TTCGTTTTCGAAAACGAAAACGAGAATTTTCGTTTTAAACGCGAAAAACG
+AAAACGAAAACGAAAATATCAGTTTTGTCCAATTTAATTGGTAAAATATA
+GATTTCATGAAATATTAGGTCCATTTTCGAATCAATAATAAACAAACAAT
+AGTTTTATTACAAAAAAAACAATAAAAATTAAATAAAGCAAAAGAACAAT
+AACAATAACACTTGCTGAACAACTATTCCATTAATCTAAACCAATTTTAA
+AGCCTAAAACTTTTTGATTTTGCTGTAAGAACACAGACTTGCTCAACGAC
+TTTGTAGACATCTTTCTTCTCAGCTTTGTAGAAACGCGGCCAGCTCCTGA
+AAAAACTCGTTCCGATTCAGCAGATGAAGCTGGAGTTGTCAGATATCTGT
+TCGCTATTTGAGAAAGCAATGGAAACTTAGATCGATTGAGCGGATTTTGC
+CAAAAAACAGCGGGGTCTGATTTTCTATTGTTATCGGTATCGTAGAAAAC
+TTCAACTTCTGCACTAGCACAGAGCATGGAATCTACAGGCGCTTTGTCTT
+TTCTTTTTCTGATCTTGGAATGCTTTTTCTCGTAAGCTTCAAACAGGTCG
+TCTATTCCCTCAAGAGTTTCATTTTCTGGCTCATCGACTGCTTCTTCCTC
+TTCTTTTGATAATCCTTGAGCTAAGCTCAAAACAAGCTCTTTTCCGTCAC
+AATATTTTCTTTTGTATCGTGGGTCAATGTTTGATGCAACAATCAGTTTG
+AATGTCACCAGTCGGTGCCCGCGCCGTAGGTGCGGTCAACGGCTGGTATG
+TATATAAAATATATTAGATTGAAAATATAACATTGAAAAAAAAAAACAAA
+CATTGAAACACAATAAAAATCAAAATATAGACGCTCTTTATTCTTGAATA
+AAAATAAGAATTACGAATTGTTCACTGGGAGTCAGCTTATTTCTTGTACA
+AAATAATGATTTTGACCAGTGTCAGCTCAAAAAAAATACGTTGACAGAGA
+GAGGTGGCATTTTCGTTTTTTCGAAAATTTTCGAAAACGAAAACGAAAAA
+ATCATTTTCGCCAAAAACCCGAAAATAACGAAAAAACGAAAATTCGAAAA
+CGAAAAAGTGACAAGCCTGATTACAAGGTCGGTATTTCATAATATGAATA
+TTGTAGAGAAAGGTTACTAGCGATGATTCCAAAAAAATTTAGATTCATCA
+GAGATGTACACCCAAATACCCAAGGCATAGGCCCTAATTATTGATTAGTC
+ACAACTTCTTACTTCCAACAAGCTTTTCCTATTTTTCCAGTTCTACTCCA
+CCGCCGCCTCACGTTCAATTGCCGGTCTCGACAAGCGGAGCCTATTCGGA
+GGAGCTGTTTCTTTTTAGTTGTATATACATCTATTCAAAATTAAAAGTCA
+TTGTTGTTGTTACCCATAAAACAGTGAATGAAAAAAAATGAAGTCTAGAC
+AGAAAATGTAAAGCTGGCACAGAATACTCAAAGAAGCATAAAATATGTAT
+AATAATGATGATATAGGGAAGGTTAGAACGTTTCAAAGCGATGTGCAAAT
+GAAGGAGCATCTCGTTGTCGGTTGGCATCTGCACATCCTTCAGCTATACT
+TTCATTCAAGTTTACAGGTCCACAACTGAACACTCCGATTTTGGATTGCT
+GCAAATTTGCTTTATTTAGAGGTTAAAAAGCATTTAACTAACCTCCTTAT
+GTTCACTCTGAATAAATTGGAAGAAAGCTTTGAAGTTGGGCCGTCCGAAA
+TGGTTCTTAGCGTGGAGACCAGTAAACATTGAAATTCCTGAGTTGGTGGC
+ACGGAAGTGCTTCTCGCAAATGTACTGCAAATAAGATGTTAAAGTTTAAA
+AGCTTCAGACCTTAAGATGCCACTGCGTTTAAATGCGTCCGCTTTAATCA
+GTTTATAACCAAACCTGACGTTTGATTTTGAAAATTATCTTCAATAAACT
+CACAAGCATAGTAGTTCTCAAATCAAACTTGTGGAACGTCTGAGTGACAA
+AGATATGTGTCTCCAAAATTCCCGACCTTGCTTGGTCTTCCACGTTCTTG
+AGCACATCCACAAACCATTCATAGTTCTTGTGAGTTGAGCACACCCATAG
+GAAATATACTTTACGGCAACGAACTCTGTGAAATGAGTCACTTGATGTTC
+GTTGTACAAGATCAACAAGTGTCGATGCATATGGAGTCACTCCGATTCCT
+GCTCCAACCATTATTGCAACTTCATAATCCATCCATTCTTGGTTACCATC
+ACCATATGGTCCTTTCATATGGATTAATGGAAATGGCGATCCTGTATTCA
+ATGATCTTATCAATTCGCTTCTCAACTTCCATGTCCATGGTCCAACTGCT
+TTTATATACAACTTCATATTCTCATCCTGTGGACTTGAGGCAATCGAGAA
+TGCGTGAGATTCATTAAAGGTACATGATATTGATGGTGATGATACAGTAA
+CCCATTGTCCTGATTTATATTTAAACTCTCTTGGACGACGGTACTCGATG
+TATATAATATCTGATGGAAGGATTTCTGCGTTTACAATTTCTAATTTTTT
+GTAATATTGCATCAAACCAATTATGCGATCAATTACAAATAACACGATGG
+GACCAACAACGTAGTAGCCAAATTTGGGAGACTGTAACAAATATTGAAGA
+AACTTCTTGAACCGAACAGTGGCAAAAACTCACATCCAACAACTTTGGAA
+GCCCATGAAGAAGAGTAAGTGCGTAAAAGGCAATATTGAGAAGATGTGTG
+AGCCGGAATGCGTGATAAGCTCTCTTAATGAAACATGGTAACGCGAAAAC
+ATAAATGATGCACATGACAGCGACCAATGCAATTCCTGTCAGACCTGTAA
+TTGTGCTGAAGAACCAGTAACTGATTGAAGGAAGGAAGTTGGATCTGAAA
+GTTATTTGATGAAAGTTGTTGACAGTCTTGAGGGAGTTTGTTAATGGTGC
+GTATTCTAGTAAGATTGAATGCAAAAATGAATTCAAGTAAAGTATTACCC
+AAAGAATGCTTCCTGAAAGAGACAAGCAAGACCTTCTTGACTTTGAGTTC
+CAACGTGATAGAAATTGACACAATGTCCAACGGTGTGAAGAGTGGCCCAG
+AAAGCCGCAAAGAGCGCAACGATCTAGAAATGTTCAGTTATTATAGAGTT
+TTTGATACTGGCGGTCATAATAAACAATACTTTGTCCGAAATATTAGTTT
+TCCCATTGTTTATCATAGTTTATTTTTTTATTCAAAAATCTGCCCTCTCT
+ACAGAACACTTATATGTAAAGTAGACTTAAAAACATCTGAGTTTTTTGAG
+CAACAAGAGACCCACACTCGTTCTAAAAAGAAATATATCTGGAGCACAGG
+AAAATCTAAACTTAGGAGACACTTTTTTGTCAACAGAACACTACACACAA
+TGAAGCAACACTGATCTAATGTTACCTTATCCTCACTTCTATTCATCATT
+TATTCTTGCCTTTTATACATCGATATTTGTGTTTTTTGCTTCTTCTCCAA
+TGTAGCCATTATTTTTTTTCTCATCTCTTTTTATTTTTGTTCCATTTTTA
+TTTATGTAACCACTTGTGATGGTTTGTATCTATTAATGTGTGTTTTTTTT
+CTACCTCACGATATCTTACTATCGTAATAAATTTAAAAAAATTAAACACT
+TACAAGTTTAGGATAACATCGCTATATCATAAGTTCACATCTGGCTGAGA
+AACACCATGTTCGATGCAAAGATCTTTCCTTTCATGCTTGTATTCTATTT
+TAAAAAATCTTTTCAAAACATTGGGTATGCACAGTACAGTTATCCTACTT
+GCATTAAACCTCCGCATTACTGTACAGATAATAAAATAACAAGTTTTCCC
+TTATATCTGAACATGCTAAATATTTTTAAAAACAACTGATTTGACAAAAT
+TTACTAATGCAATAATAATATTTAAAAAATGTGTTACACGCTGCCCTAAC
+GTTTCTCACCTTGTGGAACGCAATAGCCGAGTCAAATGGAATATACTGCG
+CAATGACTGTCTCTCGAAGAAGTGTGATTATGTTTCTACAAACTGTCAGC
+AATATCAACGCCATGCAAAATGACAAGGCTCCCGCGGCACCACGAGTAAT
+AGCGATTCCAGCTCCCATTACTCGTCGGAGATCCCTGTTTTCCGCCATGT
+AACGATAATCTGAAAACTAAATTAACATGAGCTCCCAATTATATGAACTT
+ACGCCAAAACCGTTCGAAGAAAAGAACAAGATTGATGGCAACAAAGCAGA
+AGACAATGAAAACGTGTTGGCGATAGGTCTCCAAGAACGCTGAAACTTTG
+TGGATCAAAGTTAGCGGTGCTGAACTGTTGATGGATCGATCCACGACGGC
+AAATGAGTTCAGAGAAGATGTTCTAAAAGTTATAATTGTTATACAGTCAG
+AGTCCTCCTGAATACTCACTCTCCAATACTTGGCTGATAGTTCTTTCGAT
+TGAACGGCAGTCCAACTGGTTGCTTGTCAGGTATATCCGAGAACAGAGCA
+TTGAAATCGTCGTAAGTCAGGTACTTGGCATCATTGCTCACTCCTGCATA
+GTGCAACACTTCATTGAATAATCGAAGCTGCACACTTTCAGTAATGTGAA
+CTCCAGCGGTTTGATTGAGGGACTTGACGAGTTCCGCGAGATCCTTTCGG
+AGTACCTTGTTCTTTCCCTCCAAATCACACATTTTGAATAGAGTTTGCAG
+TTTTTGCTTTTGAGGAGCTGGAAATTAAAGTAGGTGGTGCATAACATTTT
+TTAAAGGCAGTGTTGGTTTTTCTACTGTTCAGTAAAAGAAAATCTACAAT
+TGACTAAATTCTCAATACTTTGATGCCATATTAGTTGTGACCTCCCTGTC
+ACACGAGAACTTTCTACAGTGCTCGCAAATTCTATAGGACTCCCCCGAAT
+AAATTCAGATTCAGAATAAATAACCTTTAGAACTTTTACTATCTCGAAAT
+ATTGCCGACCATAGGACACCGAGTTTCACCTCACGGCTAATGAACCTACA
+AAATGTTAATCGGTCGCTAATCCCGGCCTAGTTTAAATTCAGATCAGAAG
+AAATAAATTTCTTTTCGCAGGAGACTTCGGCTCTCTTGAACCAAAACCTT
+TTATATGTAGTTTTGTACGTACAAAATCAAAGACAGTTCAAAACAACTTT
+ACCGCTACTGCTGTTACACGTAATTAAGCTGCATTAAGAAATTATATTTA
+TTCAATTAGAACTTATGTTAATGGGAAACACGCCGGAACATTCTAGAACG
+TAGTCTTTGTATCACAACAAATTTATGCTGAAATACTCACCATTAACAAA
+CTCTCTCAAGACTGTCAAAAACTCATTGAAACTGAGCGAATCCTCATTAT
+GTTTTGCAGTCATCGCGAACATTCTCTTCACAAACTCATTATTCGCTTTC
+ATTCCCATTGCACTTGCCAGTTCCTCACGAGATATTGTCTCATTTAATAT
+ATCATCATTTGATGAGTCAAATGAAGTTTCCGAATCTTGAAGTTCACTAT
+CATTGAATGCTTTTGCGTAGGCTTCACGGAAGAACAGGTCCAGTCGGTCT
+TGACGGCGTTCTTTTGTGATTGCTTGGGATAAGAGAATCTGAAATAATTT
+CCAGATTCAACGTATTTCTTGAAGTAAACTCACAGAATTCTCCTCATCCT
+TTATGATAACCTCTGCATTGATTCCACTAGCCGCCTGTCTAATTTGATCC
+AAAAATTTAGATAAATCTCTATCAGACGACAATCTTATCACCAAATGATG
+ATTATTCTTTTGAGACAGAAGTACAAATGGTCCGTGCATTGCTGATGGAT
+TCGGCATAGAGTGGAATAACTCAATCTTCTGTCCAGTTTCAAAACGAATT
+TTTCGAAGGATTCCACCGCGTGGCTTCTTTACTGCCAACGTGGTGTTTTC
+TATTTCTATCCTGACCTGTCGTATGTACTCTTCTTGAAGCCATTCCAAAG
+CATTTACACCATAAATATCTCCCTTCGCGCCACAATCATCATTTGCAAAG
+TCAGTAGTTAGGCTGTCACAAGCACTGTTGTGGCCAATAGCAATGCGACG
+ATTAACCAAGTATCGGCCAATTCCATAGCAAACTGAAAGCATTTTGGTTT
+GTATGGAACTAGATGCAATAGCTCACTTAATGGCACACATGCTAATCCAA
+TTAGGGTGAAAACATAAGTGGTGTCATTATCAGTCCAATAAGTTGATTGC
+ATAAATGGAACACATGGTTCAAGTCCAGTTGTGTTCACTTGGAATGGTTG
+CGGGCACGGGTCACCTTCCTTGAAGAAGAATACCTGGAGTGATAAATACA
+TTGCAATGCGGAATTCAAAAGAACATAATAATAAACCATTAAATTTGGAA
+AGTAACTTACATCCTTCTGAAGCATTGTCTCATCGATATCGGTGGTTGCT
+TTGATAATATCTCGAAGTGTAATACTATGAATCATTTGAACTTCTTCATC
+AGTGAATAATCCATTCAATTTATTCTCAAACCAGAATCTATCTCCATCAC
+GAATACGGGTGAATTGATCCTTTATGATTTCTTTGAACAACTCTCCAGGC
+CCATTTTCACCTCCTTCCAGCATTCTAAAATAATAACGTTTGATTAACGT
+AATCCAATATATGTGCACTGAGAAAGAAACAAGTATGCGTAATTTATTCT
+GCCTAGATTTGCAAAAAAAACTACCTTGCATGGGTAACGTTTGAAATACC
+GAAGGAATTGCACTATAAAACTGAGGTGACATACAACTTCCAGAGTTTAT
+GCCTGCTACAAATTTTAGAGTTTGACCAAAAGAAGCCGTTAGAAGTTTAC
+TCGTGAGAACTTTTTAACCCTTGAGAAGATTTAGTGAATATTCAAAATTC
+CACACTTCTTAAACCAATCAGTTATGTTAAAACGAATTGATTTTCATTGT
+TTTTGCTTGAAACTCTTCGAATTCACCGCATTTTAAGTTAAGCATTCCAC
+TTTAAACCCAAAACTAACCCTCCTACATAAGCATCCAAATATAAAATATT
+GCCTCCATACAACTCTTTCAACTTCTCCACCTTTGCAGTATGCTTCTTGT
+AAAAGTCTTCATTCATTGTCTCCCATGTCTTTGGCGCAAGTCCGAATGTT
+CTTCTCAATTCATTATACGGTGGTACTCCATTGTCCCTTCCTCTCATTAT
+TGATGAAGCAACAACATCCAAACGAGAGAAATGCATTGGTCCGAAGATGT
+AATCACGAAGATCTTCAACTACTATGTTATCATCTCGTTCAGCTATCTGG
+CTTGCCATTCCTGAAATTACAACCTTTATTATATAACCACTCAAGCATGA
+ACTAACCAAGAATAATCTCATCCACACTGTACTCCTTTACAATATCCTGC
+GCATTCCACCAATTCTGGCACAATCTCAATGCAGGATATCCACCAACTTC
+CGTCCGGAATTCACATTTATTTCCTCGTTTTCTCAGAAGCATTGCTGGTG
+GCACAATTGAGTGAGGGAACCTGAAGGCGGCTGCTCCAAAAGCATGCGAG
+ATTCCAGGTGGAACATGTGGCATGTATTTGGTGTAGTTTGACAAACGAAC
+GTCTTCACCTTAAAAGAAACACTGAGTTTAAGGTATTATAATATAGTTGA
+TTAACCTAACAGCCCTGGAACAAAGTCATATGCAATAATCTTCTGCATAG
+ATGCAATCACCAAACGACGTGCTGCCTGGAAGATTTGTTCGTCTGTCCAG
+TCAGGATGTTCTCGATGGATTTGATTTGCATTGTAGTTATGCCAACGGAA
+GAGGATCAGACCAAATGAGAGAAGACCTGGATTCTCATTCACACGCGAGT
+CTCCCAACACTTCAAGTTTAAATATTTATACTTTTCTATAAAACTATGAA
+CTCACTAAATAATCTATCTGGACTCATCAATCGATGTACTTGTGGCGGAG
+CGGGGTTATTCAATGGAATATGTGGGTTGTTAAGTGGTGGATATCCAGGT
+ACACCTTCAGCCAACCGCCCTTGTTTGAAAGATCTTAATGAGGACACCCA
+TGGCTGGGTGGTACCATAGATGAATGATCCATCAATCCATGAAGTCCGTT
+CATTGATTTGTTCTCGAGGTGAGTTGAGCCCATTTCCAGTTGCTTTATCG
+TATTTGGCACGTGTAAATGGGATTTCTGTCTTTCCCTCACATTCTTTATC
+AAATACATTATCACATAGGGGTACTTGAATTTTAAGTGTCTCTAGTGGAC
+AGGATACTCCATTTGATTGCATTATTTCATAAGCAACTACTTGACCTATA
+ATTATTATTACTAATTTTTGAGGTAGAGGGCAATAAAAACGAACTGAAAA
+ATGCCAATAAAGTCGTGCATCCTCTTGTATTAGGTATACCGGACTCTCCT
+TTGAATAGTATATCGGAGAGTTCACGGGCGGACGGAAGTGAGTTATTCAC
+TGAATATACACCGTCTGAGTAGTAGGAACGTGCATCTCTATGCAGCCGAC
+TTCCTGAAGGAGTAGGTCAATGTAACGTCATTTCTCTTCCGAAAAAACCT
+ACCAGCAGAACCCCATTCACTATTCGCCAGATTGTTGTACCATCCGTCGT
+ATCTTTGAAATTCCTCATTTTGTTGGATTCCTGAAAAGATAAATGTTACG
+AGTTTTTGATTTCCAGGCCACCAAAATCTATATGATGGCCTAGGTTCCTT
+ATTGAAATTTCTAGGTCACACATGCTCCCTTCACTACATTTTCACACCGA
+TTCGTGCATTTTCTCACTGAACGCGCAAATTTCCGGTCAGTAGCGGAGCA
+GAGCAAACATTTGCCCCGCCACCCGAAACAATTATTTTCGTATCATTTTC
+GCACCTATATTTATTCTGTTTGTTTGCCTATTTTTTGTACATTTTATCCT
+TTTTCTTGTATTGGGCGACGATGGCAAGGTCAGTAAAACAGGAAATTGTT
+CCTGATAACTCGGGAATTTCAGGAATTTTTCCAAAATTGGTTGGGAAACC
+ACCACTTTGTTGAAATTCGAAAGATACACATTTTGTTATTTAGGTGTAAA
+CATGAACACTTTCTTAGGTAAACTATGTGATTTTTATGAAAAAGAACACA
+GACACCGGGTGGCACACAGAGCTTATCAGTAAACAGCTATCAGTGATTTT
+GAAATTTTGGAGGGGCAGAAATGTTGCGGACAAGGAAAATTTTTGTTTGG
+AATTTGAAGTTTTGAAATACGCAATTTGAGAATTTTTGAACATTTTTTTG
+TAATTTTTATCCCATTCATTTTTAACCTAACATTTTGAAAATCTAGCACA
+GAAAATAGTACAGACACGTTCAATTGAGCTATTCCAAAAATTATCAATAT
+AGCGCACTTGGTGTCCATCTTCCTTAACTGTTTGCAATTAGTCTCTCTTT
+ACAAGAAATCAGCTACTATTTGAACAGATCTTGAACACATTTTCAAAGAT
+CGGCTCAAGATCAAAAGCCTCTTAAACATTTAAGATAGCAGGTCCGCTCT
+GTTGACAAATTTTCCACCCGGTCCTCCGAAAGGAATTTTTTTGGTCATCC
+AACAACCTAGACCATGACGGCACCGATCATGCAATTTGCCTGCTTATAAA
+AAACGATATTTCTAGGCCACCCATTTTTAAATATTTTTTTGCCTAGTCTT
+AGCTATGTGGAATAAATTCTAGGTCAGGAGGTTTTCTAGGCCACGTAATT
+CCACTCACCTTTCCCTCCAAAAATTGAACTGAACAGTATAGCTATGTACA
+GCACATGTTTTGAGCGCATTGCTCGTGCGCCTTAGAGTTTTAGTTGACCT
+GAAAATATTTGAATATTTAGAAATTGAAATTTTGAAACGCAATGATTAAA
+ACGGTCAAAAAAGATGTTATTTATACATACGCAACATTTCAAAATTGATA
+ACAAATATTTACAGGAACACTTTTTTCCAATAATACGGTGACTAAGGGGG
+AGTTTACTGATAGTAACAAATTGGAACGGTACAGGAAGAAAATTTAAAAC
+CGGCTCTACCCATTTTAGTGCTACCAGCCGACAACCAAAAAAATCAATCA
+GCCGCACACCCTGCTTGGAATGTGACAATCACAGAGTTTTGGAATTTTCC
+TAATTTCTAAAATTTAATTTTCTAAAAACTGGGGATTTTTTCTGTAATTT
+TTTTTTAATTTTAAATTATTTTTTAGGAACATTTTTTTGAAAATAACTTT
+TGTTTGAAAAATTGTTCGCTAAAAGAGTATAAATAAGATCAGGCTTCCGA
+AAATGTTTCAAAAAATATTTTTTCACGATTCTTGCAACAAAAAAAAACAA
+ATACTGAAAAAAAAATTGTAAGAAATTTATTTTGTTGAACTTTTCAAATC
+TACATTTACAACAAAAACAGTTCTTTATAATATTTTAAAATCCAAATAGA
+TTCCCAGTAGATTTTGTTTAAATATTCGGAAAACGACCAAACTTTCATTT
+TTTGAGTTCTTAAATTAAAAAAAAAATTTTAAATTAAAATTTTTGATTTT
+CAGTCTAAAAATTTCAAAAAAGAGCTTTTAGTTCTGTAACTTTTGGAATA
+AAAATTCAAAAAAAAATTGGGGGAGCCAAAAACTAACGCCTGCTTGAAAC
+CTGCCCGCGAGAACTTGCAAATATTCAATTTTCTCATTTTTATTAATTTG
+ATGAGAAAAATTTAGAAATAAAAAAAAATTTGCATAAGGCATCGATTGAG
+GCGAAAGGCAGGCGGAGGTAATTTTAAGGCCAGGCTGGCGTTTTAACTTA
+GGCTTCCATAGACCTAATATTTTCATACTTGTTGAAATTTCAGAGGTTTG
+AAAATTGAACAATTTAGGCCCAAAACCTTTGTTCCTACAGTACTACAAAA
+ATTCTTTGAAAAATTCCGGTAATAATAATTGGAGGAGGAGGAAAAATATA
+AAATGATTCTTCGTCAGACAGAAATAAATTGGTGAAGAGAAAAAAATGAA
+TTGAGAGAAAAAGAGAAAGAAAGACGGAGAGCGTCTTCGAAAGAAGGAAT
+CCTCCTGCGCGGGATCGAAAAAATAAGCAGCAGCCGGGAGTGAGAGAGTA
+CACTGCACTAGAAAAGATGCAGAGAGATTCACAGAAAATCGGGAGAGACC
+CCCCGTATGTCGGTCGAGACTGAACACCTAAGACCTACTTCATATTTCGA
+ACCGGTTCATTTTCATTGGCATTCGTATTATTATTAGTTTTGACAGGGGC
+AGTCGTCGTAGATGCTATTGTTGTCAGTTTGACGTGATGGCCGTGTCATG
+GGAAAAATTCGGCCATCAAAAATCGGGGGGTTCCTGCCACCCTTTGTCTT
+CTATGGTCGGAGAGGCGTTTTCTAGGCTACTTATTTTGGTAGAGTAGCTG
+TTAATTAAAAATTTCATCAATTTGGTAATAATGTGGCTGCAAATCATATT
+TAAATTTTCTATACAGTCAGTGCCACCCAATTAAAAATTTTCTGGCAGTG
+CCACCCAGAAAAAAAAAATATCCTAGGCCACCAATTTTTAAGATCATTAA
+TTTTTTGGCTATCAAATTAAGTAGACCACTAAAATGTTTCGTCATTAAAA
+TTTTCTAGGCCACCAATTTTGCTTGACTACTAACCTTCTTGGCCATCACA
+ATTTCTAGGCCACTAATTTTTTTTCTAGGCCACTAATTTTCTAGGCCACT
+AACAAACTGTTCAGGCCATAAAGTTTTCTAGGTCCCTATTTTTAGGTCTT
+CAATTTTTTCAGGCCACCAAAATTCTATTCCAACATTTCTCCGTCACCAA
+AGTTTCTAAGGCCTTTAATTTTATAGACGACTTCTTAATTGTAAGTCAAA
+TTGTTTCAAAACGATTATTTTCAATACATATCAAAAACCCAAAATTTTTC
+AAAAACTTAGTAAACTAAACTAAATTTCCAATACGTGCTTCATTTTTATA
+TGTAGGCGTTTAGACACCCCAGTGGGCAGCAGTAATTGTTAATTCTTATG
+ATTATCTCATTGGTACACTTTTCTTGTTCAACTTTAATTATTTATTTTTG
+AAAAGGATTATCATTGGCATTGGCAAATAAATAAAATTGTTAGTGACGTG
+GTGATATTGGACATTTTTTGATTTTAGTTTGCTTTTTGAAATTTCAATTT
+TCGGCACTTTGAAATGTTCAAAATGTTCATTTGTATAGCAAATTATTTTA
+TTAAAATTTTTTTCAAATTTATTACATTTTCAGTGAAAATTGCACAATTT
+TTTAAAACTTTCTAAAAACTGCAAAAAAATAATTAGGTTTAAATAATCAA
+ATCAATAATTTTTTAAAGGATTAAAATAAAATTATAGTTATTACAAATTA
+TTTAAAAGATGTATACTTAAAAACTACTATTTATGTTTTGATTTTTACTC
+GAAAATCCAGAAATTTTAAGTTTTCGAGAAAACTTTTTAAATTTGTTTTT
+AAAAGAGGTTTATATAAATATAATGAACCCAAACTTGAAAGTGCGAAAAT
+GTACTTAAAAGAGTCCAAAATAAGCAAATATCATCACGAAAAGCTCCGAA
+CGTTTTTAAGTTTTTCGAAATGTTCAGTTATAGTTTTGGTAAACTGCCAA
+CTTTACGAAAAATTCGGGTTTAATTTTCAATGTTTTTATACAAATATTTA
+AAACAGAGTAATAGTATAAAATTTGTAAAAAAAAATTTTTTGGTCGGTAT
+TTAAAAATGGTGATAGGTGATAGGGCCATTTTTGACAGTAAAAAAAACTT
+TTATAATTGTTTTACATTTTACCAACATAGGAGCTGCCTTAAAAAATATC
+TAAAGGCTTGGGGTTTTGCCCTACAGTCCCAAACTACCAAATATAAATGT
+AAAATTTTTATAAAAATGTTCAAAATTTTTAATGATTAAAAAAATTTGCG
+AAACTTAATCAAAATGCCGAATAATTGTTTCATTCCCGCGATTTTTTAAT
+AATAATTTTTTTGTATAATTTTTGCATTTAGTGGCGTCATTTGTTTACAT
+GTTGTGTTTTTCGGCAATATTAATAGAGGTTTTCAGAGATTTTCTAGTTT
+TTGAAGCACATTTTGCCTTGTTCCCGTAAAGAAAACTTGATAATTGGAAA
+GAAATTTGGCAAAACGGCGAAATTGACCAAATTGACCAAAAAAGTTAACA
+AACTGTATTTAAAAATAAATTATTAAGCAAAGTAAAAACAAAGAAAACCC
+ACATAAATGTCAAAAATGACGTCACTCATTTGAGCTGAAATTCAAAAAAG
+AATTCGGTCCTTCTTTTTTTTTTTCAAAACAAATTTTTCTTAAATCATAA
+AAAACATATTATAATTTTATGACTTTTCTGACAGTTATATTTGGAATAGT
+GGGACATTTACAAGGGAAGTCGAAAAACTGAACTCCGGACTTTGACATGC
+TATAGTTATTTTTCGATAAAAGAGTGAAAATAATGATCCCTCCAAAAAAT
+TTTGCTGCCGCGGACCAGGTTCAGCAAAGTTATGACGTTTTGAAAGTGCC
+GAAAAAAATTCCTTGACCAACCCAAGCAAAAAAAAACTTTCAAATTTTCA
+AAAAAAAAATTCTGAAAGTTGATAAAAACTATTGTAACTTATTCAAAAAT
+GTGAAAAACGTATATCATGCACGTTTTTTCTCCCCACGGACAAAAAACCA
+CATTGCTTGATCAAAATATCTTGAGCAAAATTCTAAAAATTACTTTTTCT
+TGTAGATTCATTTATTGGTTTTCTTCAGAGTTATGAGCTAAAACTTGCAT
+GGCATATGTTTTTCACTGTTTTGAATAATTTACAAATATTTTTTCCTCTT
+TTCAGAATTTTTTTTTTGAAATTTTTGAAATTTTTTAAAAGGGTGTTTCA
+GCCACTTTCAAAACGTCATAACTTTGCTGAAGCTGGCCCGCGGCAGCTAA
+ATTTTTTTGGAGAGATCGTTATTTTCACTCTTTTATTGAAAAATTACTAT
+GACATGTCAAAGTCCGGAGTTCAGTTTTTCGACTTCCCTTGTTAGGGCAA
+AAAATACCCACAGACGGTACTCCGCCTAAAATCAAAAAAGTTCCAGCAAC
+TCGAGATCACTTTTTTACCATCTCAAATCGTTCGGTTTGTTGGGGGGGGG
+GGGGGGGGGGCTTAAAGAAAAACGAAAAAATGAGACACTTGTTAATTTGA
+TGGTAACAAGTGAAATGGAGAGAGAAAGAGAGTGTAAATACAAGAAGGGA
+ACAAACACTTGAAAATCAAAATTGTCGGAAGGAACTAGGGGGAGGATAAA
+ATATTGGAAATTAGGTTTAATAGGATATGTATCTAATCCCGAAGAATATT
+ATTAAAATAATCGGTTCAAAGAATCTGAAAAAATCGATAAATGCGTTGTG
+TTGTCCTACTTCCGTCCTCTACACAACGTCGTCTTCTTCTTCAGGGCGCA
+TTCTTTTGTGTAACAGTGCCCCTTTTCTCTCTTGATGCCACAAAACACTT
+TGGCAGTTACGCAATCGAAAGGCGAGGAAAGCAAAACGGGTATCAGATGA
+TGATTAAGTGAAACTGGAACTGATAAGTGAGATGGATTGAAATACAGATA
+GCCGTAAACTTTTAATAACCTAGAATTTTAGTTATTAAAGGTGTTATGTA
+TGTTTCGAAATTTGAAAAGATTTTCTCAATTTTTGAATGAATTATGTTTG
+AAGTAATTTAAAATGCCGAATGAAGGGTTTCAATTTTTGTTTTTTTAAAA
+AGATTTTTCGTCCGGCCGATTTTTCGCAAAATGTTTTTTAAAATTTGGGT
+TTATGTTCTTCTCTTTTTTCATGCCTAAGCCTAAGCTAGGCTTAGGTTTA
+GGCTTACTAATCCTAATCCGAAGCATAAGCTTAATCCTAAGCCTAAACCT
+CTCCTACTCTTTTAAGCTTAATGAATGCCCTAGCTTCATTTTTTTCATTT
+TTCGCAGGTTTTTTTCTCAAAAACTCAAAAGCGATGCTACGAACACCAAA
+AATTGGTGGTTCAAAATGTGTGTTTCTATTTTTTTCAAAATTTATTTGAC
+TATACAAACCAGCTGACAATTTTCTTCAAAATTCCGTTTTTCTTATCAAA
+AATAGTCAATTTTTCATCTAGAAACTTCAAAAAACCGTTACCGTTTCCCT
+AAGTTTTGCTATCAGTTCCGTAAATCTTGTACCTTATGTCACATGGCATT
+AGAAATATTTCAATTGAACCAATCTTGTTCGCGTGGAGTACAAGTTAAAC
+ATTTATGATATGTGGATGGGTGCAATTGCGCTCTATTGAACAAACTATGT
+ATCAACAGAACGCGTTAACATTATTTGTACAGGTGGGGAAAAACAGGAAA
+AACGACTAGGCAAAACAAAAAGTATATAAGTTTTCTTCTACACGTCTCAT
+AAAGGAAATTCAAATTTTTTAGAAAAAGAGCGGGGGGGCGCGATTGCAAA
+GGTTTAGACGGCGTTAAGATCTTTGTCGACGAGTGGTTCAGCCGCTGAGA
+ATGTGATTGCCGCCGGAATATTGTCCTTCTCGTTGATTGAGTCTTTCGAG
+AAGAGCGCCAGAATGACGGGCAGAATGAAGAGACCGTGGAGGAGACCTGG
+GAGAATTTTAAAATTTTTGAGTTTCTAGGCCACGAGTGACGTCACTATTA
+TGTCCAAGAAGATATTCTAAGGACAAATTTGATGATTGTTCACTACTTTT
+TCACTAAAAATCAGCTTGAATCGTAGAAAACAAAGAACTTTCAGAAAATT
+TCAGCGCTCACCAATAGCAACGACCAAAAAAACGGTCTTAGCAAAGCACA
+CGATTGCATAAGTTGGCACAAAAATCAACGGAAGCATGCATAGGAATGTC
+GACAGTCCGGCTTCACACATTGGCATTGCCATTTCTGCCAGACTACTGTA
+GACACGTTCTTGTGGAGTGCCACGTGCACGAAAAAAGTTGTAGGCCACGT
+GAGCGGTGTAGTCGACCGAGAATCCCGTGGCGAGAAGGACGTCCACTTGG
+ATTACCGGGTCCAGGTCGGCACCCCAAAGGGAGAGACCACCGACGAGAAC
+TGTAAAAACGATTTTAAAAAAAAGTAACTTTTTCAGATTAAATCCAAGAA
+AAAAACATAATTAAAATTTGTTTCAATGGTTTTTTAAAGTGACAATTACT
+CATTTTCAGGTTTTAAAAACTTTAACTTGAAAAAAAAAAACATTTTGAGC
+TACTTTTGAAAAAGGTTCTATTTTGAATTTCCCATCCAAACTTTTTGAAA
+AAATACAAATGATAAAAATAATTGCTTTCTTAAAAAAAAATTGTTAGCAA
+CCCTACCGTTCGCTAAAGATCGTTGTCGTTTTTTCTCAGAAAATTTAAAT
+ATCCCGCCATATATATTTTCGGAGAATTTCAATTTCTCGAAAAATTGTTT
+TCTCTGAAAATTTGAATTTTCCGCCAATAATTTTTCTCAGAAAATTTGAA
+AAAAAGGATTAAAAACATGAATTTTCCGCAAAAAATGTTTTCTCAGAGAA
+TATGAATGTCCCGCCAAATATATTTTCAGATAATTTTAAAGTCTCGCCAA
+AACGTTTTCTTCGAACATTTTAGGATTATGTGTTGAATTTGTAGAATTTT
+GATCTTGATTTAAATTTTTTCAGTTTTCAATTGAAAAAAAACTAACCATA
+ACAGATACTTGCAATAACAGATGTAATCACAGCAACTGCATTAAAATTTG
+CAATAAACACAAAACAAACGATTGCCATACAGACTACCGTAACCGCAATC
+GATCCAATTAAGTCAGTGCCAACAGTCAGGATGATACTGAGAATTGCAGA
+GTCACAGTCAAAGAGTGTAGCGTTGAATTGACTTTCTTCATGAAGAATTG
+TTCGGATATGTTGCATTGCACGTGCTCTTTCTGCCCATTCAGACATTCCT
+TTACCGAGAAGTGTCAGACGGAACGCTGTGACAATTGTTCTGAAAATTTG
+GAAATTATTCGGATTGAAATTGAAAAGTGTATAGGAATTAAGTTTGAACT
+ATTTGAGAAGTTTGTATTTTAAATTTTGCGCTAAGTTGCCTGAAAAAAAA
+CTAATTTCGAACTATATACCTACAAATATTTTTCAAAGAGCTCAATATTT
+GAATTTCGCGCCTAAAATATTTCGAAAACTTAAAATTTGCGACAAAACTA
+TTTAAACTATTTGAGAAATTTGAACTTTTAATTAACATTTGAACTTTGCG
+CCAATTTTTTTTTGGAAAATATTAAACTTTTGAAATTCTAGTTGAAAGGA
+AATTCAGAAAAATTGAGGATGTAATTTTTTTATATGAAAAACTTTTAGAT
+TCGATTTCGCGTCGAAAATTTTTGAATTGTCAAAATTTAAATTTTGACTT
+TTGCAAAAAAATGGCGGGAAAGTGAAGTTTCATTAGGAAATTCAAATTTG
+ATAGGCGTTTGACTAACTTATTATCATCTCCCATGTGATATTTTACAAGT
+GGAGGGTTCCCGATCGCATCCATCCACGTCGGAAGATTATCATAAGATGG
+GCGGTATTTTTCTCCAACCAGAGTGGATAAAATATTCATCGTCTTATCAA
+AATTCACATATTGCGGAAGAAAAATCAGACTTCGATTGTCTCCACGAATA
+CCTGGCACGTGCTCGAGCCGATCCATCATATTGTTGAAAGAGTCGTACTG
+AAAATTGAATGGCCTAGTAAGTAAAAATTAGATCATGAACTTACCTCTGC
+TTTGATCTCGATATTTGGAGGGTTGTTCACTATTACTGTAATAGGAAAGT
+AACGGTTGAAGACTGGCCTGAAAAATGATAAATGCTCAAAAAATACAACT
+TTTTTCTTTTAATAACGTAAAAAGTTTTTTAAATCGATAAAATCAATAAA
+TCGGCATTTCAACTGTAAACCAAAAATAACAATTATTGATTTTTCTTACA
+AAGACCTTAAAAATAAAAAAAAATCAATAAAAATAGCGATTATCTTTCCA
+AAAATCTGAAAATCAATTCAAATAATTTTCTTGATCTTTTATGTTAACCT
+ATAAATACCAATTATTGATTGTCTGGAAAATCAGTAAAGATTATTGATTT
+TTTTGAGAACCTAAAAATCAATAAAACCCAATAAAAAAGTAATGTTTTTT
+CAAACGCTTTTTCAAACAAATTCTTGATTTTACTTTCAAAAAACCAACTT
+AATATTCGACAACGAATCCACCAGCTTCGAATTTGATGGGAATGCCTTTG
+CAGGTTCAAAGGTCGTTTTCATGGTGACTACTCCATAAGTTGTCAACGCA
+TACATCCCAAGGAGCACCATAATGCACGCTACACGCCCCTTCACGGAGCA
+CACGAAGCTCGAGTACTTGGAGAGCCACGTGTCGGCTCGGGAAATTTTTG
+GCTCCGTCTCATTGGCGATGGATTTGTAATCTGGGTCGTTGCAGAGGAAT
+ACAATTGGAGCTAGGATCGTATAGGTGAAGATGTAGTCGAGGAGCAAGGC
+GAGCGAGGCAGTTAGGCAGAACAAGGACATCTGGAAGAAGAGTTTTATTC
+AAGCTAGCCCACGTTTTCAAAAACTGGGCTACGTGCCAAAAAAGGTTACC
+TGAGGCGTTGGCGTCAAGAATCCGATTCCAAAAGCAATAATATTGGTAAG
+TGAGGTGATTGTAATCGATGGTCCAACATCGACAATCACTTGTTCCAAAC
+GGCGAGGTCTGAAAATTGCAATTTCACGATGCTTTTACAATACCCCTACA
+GTACTTTTGCAGTTTCTCTACAGCACCCCTGTACAACTACGGTACTTTTA
+TTTATTTATATATTTGTTCATCAGGCAACAATCATAATGATACAATTACA
+ACAAGGCAGTGAACTTTTACAATACAATGCCCCACCCTCTTTTTCCGTGA
+AAACTTACGTGTCAGTAATTGCAATATGATGTTTCCATCTGTGAAGTAGA
+ATAAAAGCATCATCAACTCCAATTCCAAGTACCAAAAACGGCGTAACACA
+TTGAATAGAGAACGACGGGAAGCCCATCCAACAAATTGCTCCAAACGAGG
+CGACAGTTGCAGCCATCGGAGTGAGCAATGATGTGGCAACCAGATAGAAT
+GCCATTTTGACAGATGACAGGCGGACAATGACAATGATGACCTGAGTCAG
+AAGTAGGAAGAATCCGATTGTCATTAGAGTGGTAGCTTCAATGGCTCCTC
+GAATCATTTCACGATTTGCTACTTGGTCACTGAAGATGGTGAACTGAACG
+TGCTCGAAGGCAGAGGAGTTTTTGGAAAGTTGGAAGAGCTCGTCGATTGC
+GTCCTGGGAAAAGTATAATTAGGAAATGCCGAGTGCTTGCCAGTTTTTTT
+TATTATGTAAATTTGCTTCCCAGAATCGCGAAAATTTGATTTCCCGCAGA
+AAAGACTGAAATTTAAATTTCTACTAAAAATTGTTCAGATGTTTGTTTTT
+AGAAATTTTCTTTAAAGACAAAGATTTGAATTTCCTATTGAAAATAGGTG
+AAAATTCAAATTTACTACAAAAAAATTGAGTTTTGTTAAAAACACACTGA
+AAAATTGAACTTCCTGATTAAAATTGATTGAAAAATTAGAGGCTCCTAAA
+AAATATTGAAAACTCGAAATGTAAATTCAAATTTCCCGTCCAAAAATTGA
+CAAAAATATTTGAACTTTCTGCCAGAAACAAGTTAAAAAATCAAAGGTTC
+CTCTAATAGTAAAACTGACTCAAAATTAATTGAAAATTGATCAAAAAGCC
+GTATGAGTCTTCTAGGCTATTCTCACCTTAAACGCCAATTTTCCTTCTGG
+AGTATCAGACCTCGAAAAATACCACAGCACCAAGGATTTGGAGCTGATCC
+TCTCGGTCGGTGGTTCTGAAAGTTTCAATATTTTTTCACATTTTTCCAGA
+ACTTTTTATAGTTAAAAAAATGAAATTTTAACTGGAAAGTGGCTAAATCA
+TAAAAACTATTTTTCAACTTTTCATTTAACATTTCAAAAAAAATCTTACC
+AAAATCCGCATTACTCAAGTGAAGTCCCAGGAAAATATCCAGTCCGCTAT
+ATGGCATATCCGGATAGGTGAATACACTTGTGGTACCATTGTTTCTCCGC
+GTCAAATTCTGAAAATTGCCATGTGGTCGTTGAAGAGTTTTCTAGTCCAC
+CACCACCACCACCAAGGGTTTCGGTTTTTCGACTTTTTAGAAAATCGAAA
+AATCGAACAATTTTTGAGAAAAACTTACAAAAAGCTGATAATGTTTTTAT
+TTTAACTTTTTTCTCCATCATTCATTTTAAGAATATAGATAAATGGGATA
+AGACCGTCCAGGTTTCTGTTCAGTTTTCCCTGTTGTTAAATTCATTAAGA
+TGTTTGGTCCCCAAAAAACAATGTTTCTTTCATTTTTCGATTTTCAATTT
+TTAGATTTTTCGATTTTCACTAAAAACATCGAATAATTGAAAAAATCGAA
+AAATGACACCCTAGACCACCACCTACCGCTAACAAGTGAAAGGGGCTGTT
+CAAGTCGCAGAGTGGATCGCAATTTTTTCGTCCATCCCCATCTTGGTAGC
+CAACTGCCGCCGATAGTCGATTGTCCACAGTATAAATCTGAAATTTTTTA
+AATTCCCGCCAGAAAAGTGGGCGTGACGGAGAATCAACTTACGTCTGCCA
+GTGCGCCTTCCTGGAGAATACTGGAATTTTCGCGCTTGGCGGTAAAAATA
+CAGAATGCTCGTTCCGGATAGATGTCGAGTCCGTAGTATTCCAGCCAGAC
+ACGGGTTTCACTGAAAAATGTAAAAAAATTTATAGAAATTTCCGCAAAAA
+GCATATATTTAAAATAGGAGTTTTAAAAAAATTAACAAAATAGTTACGAA
+CGAAATTTTCATTTGCTTTAAAGTTTTCTTTTTTTTCTTATTTATTTTTG
+ATCAAATATTTATTTTGGGTTTTTTAACTTCAAGTGGAATTCCAAAAAAA
+TTCAATTTTCTTCCCAGTCAACCAAACATTGACCAAATCACAATAAGAAA
+GGGAGAAAGGGAAATCGAATTAGAAAAAGAAAAACATTGCGAAAAAACGT
+GTTATTTCTGACTGGTGGAGGAAGGAGGCTTCAAGGTCAGTAGTCACTTA
+CTATCCAGCATCTGAATCATCCGGTGAAAAGGCTTTGCGAATATCTGGCT
+CTAAACGAATGTGCACAAGTCCTGAACTGAGAACTAGGATGGATAAGATG
+CTCACTGAAAATTGTCCAACTTGAAAAATTTCGATTTTTTATGTTTATTA
+AATTTTTTCTGGTGTAAAATAGCAGAAAATGCCAAAAAAAAATGTATCAG
+ACACAACTTTTTTTCAATTTTTCAAACTTTTCGTTGCAAGACCAAACATA
+CAATAACAATTGTCGTTCGAGCGCGTTTTGCCCATGCACCCTTAACGGAG
+ATTTTCATCGACTACTCTATAGAGCGCGTTGGTGATTTTGAAAATGAATT
+TTTCTTGGAAATTTAAAACTTTTAGAAAGGGATTTTTCTATTTTTTCCAA
+AAAATTATATTGAAAAATCAATAAATTAATTATTGATTTTTCAAAACTAT
+AGTGATTCTGATTTGAAAAATGAAAAACATTGCTTTTAAAATTATCTGAA
+CTCAGTTTTCACGAAAAATCAATAAATCGGTAATCGAAAAACATTCATTT
+TTCTATTTTTCTCAATTTTTCGATGTATTTTCCAAGAAAATCGATTAATT
+TATCGATTTTTTTTCCAGAATATCTGATCGATTTTTTTATTCATCGGAAA
+AGTTCAATTATTTTATTTTTAGGAAATTGTTTTCCAAACTTATATTGGTG
+GCCAAGTTTTCCCATTTCGACGACCATAAAGTTACAAAAAACTCACAAAG
+TATCGAATAAACCGGATAGGCGGCTAACAGCCGTGCCACGACGGCACTAA
+TCACATCCCATCCCATGTGCTGAAAAACTTCGAAATTTTTTTAATATTTC
+AGAATTTAAAGCAGCATGCAAACGCGCTCCAACAAAGAAAAATGTTTTTA
+AAAAATTGAAATTCAAAACACAAGCACGTGAAGCAGAGAATGCAGAAAAC
+AAGACCACTGTCACAAAATTGTAGAAGTGAGGGAGGGAGGGCTATTGCAG
+AGGTGACCAACGGGTTTCGGTTTCCAATTTTTCGGACACGGCGCAGAGGA
+TTTGAGTCATTATTATTGTGTTTAGAGAGTGTAAGAGAATTAGAGAATTA
+GGGATAGATGGGAAACTGTACGTACTTCTGCGAAATGGTGCACTTTTAGG
+ATCGGCGGCCTAGAAATTTACATGGTGCTCTAGAAGTCTAATAGATAGCC
+TAGATCTTTTTAAGTCCAGAAAATTACTTGGTGGTCTAGAAGTTTTTTTT
+GTGACCTAGAAATGCAGTTGGTGGACTATAAATTCACTTGGTGGCCTAGA
+AATTCATTTGGTAGCCTAGAAATGTACTTGGTGGCCTAGAAATTAACCTT
+GAAGCTTAGAAGTTTGTTTGAAAGCCCAGAAATTCACTTGATTGCCTATG
+AATTCACTTGGTGGTCGAGAAATGTTCGTGAAAGCCCAGATATTTACTTG
+GTGGTCTAAAACATTTTTCAGTTCAGAAATACATTGGAAAAAATTTCGAT
+TGAGAATTATGGCGTGGGATTTCAAGTGGTGACCTAGAAATTTGTCAAGG
+GACTGAGGAATTCATTTGGCGTCTGGAAATTTTTTTGGTGACCTAGAAAT
+TTATTTGGTGACCTGAAAATTCATTTCATGACCAGTGAATTTACTTGGTG
+GTCTAAAAAGTCTCATGGTGCCGGTCTTAAAGTCTCATGTGTTGCAAAAA
+TTATACTACAATATTTAACTTTGAAATAAAAATTCAGCGGGTCTAGATTT
+GCAAGAAAAATCTGTATTTTCTCAATTTTTTTCAGGTTTTTGATTAGTTA
+AAAAAAATCGAAATGATTGTTTAGAACTGCAGAGAAAAAACAATTTTGTA
+TCTCCGGAATGCGCTATTCTGGGGAGTCAGATTTACTGGATTTTACTTTT
+TTTCCTGCAATTCCAATGCAAAATAAGGTAAAAAAATGAGAAAACTGGCG
+GAACACGGCGGTACACACAGGGGCAACTTGAATGTAAGGCAGGTGTTTAG
+TAAGTGGACCGAGGGGACGGCAAAAGCTGGTATTTTTCCTGTGTCGATGG
+GGGACAGTAGTAGCACACAAGAAACAAGTATTTTGATGATAATACGAATA
+AGAAAAAGAAAAAGGCAGCAAAAAAGTGTGTGGCAGACCACCACCGTCCA
+TCGGATTAGGGAGCGGAGGCAAACTCGCTCTACCGAACAGAGGGGTGTCC
+GTTTCCCCCAAAATCCTCTGAATGTGACGTCATTGTTGGGGCGGCGGGGC
+GGCGTCCAAAAATTAGTGATTTTTTTTTTGGTATTTTGGAAAAAAAGGAA
+AAAATCGAGAAACATTTTTTTGTGTTTTTGGGGAGTTTGTCATGTGAAAT
+TTGAAAATGTTGGGTACAATCAAAAAATTGTTTTGGTTTTTATAATTTTA
+ATAGGAATTTTTAAAAATCTGAATCGTTTTTCTTTGAAAAATCAAAAAAC
+AACAAAACATCCGCTTTTTTTAAAAATTGTTTGTTAAAAAAATAGAAATC
+GGAAAACAAAATTTTCCGATCTTCTCGAAATTCACAAACTCATAAAAAAA
+TCGAAATCCCCTTGTACCCCACCCTAGTTCACTGAAGCGCGTTTGCTTTC
+TGGCCAAAGGCATGGAGGGAGGCGGGCACCTCCCTTTTGCAAAATTGACC
+TAAATAAAGGTGATATGCCAGTGATAAGGAACGGTTTAATGATCCGAAAC
+CGCCAAAAGTGCATAGTTTCTGCGTTAAAAAAAGTGACAACTGACATCAC
+ACGGAGGCTACAAAAGGGGACTCACAAGTTTGCCGGAGAGGAATGAAAAT
+TGGAAATTTGTACGGGTAAGGGGATCAATGTTCAGTGGTGGTCGCGAGGG
+AGGACGGAGGGAAAAAGTGGAATTAGAATTGAATGGGAAATTGGTGGCAA
+AACGGTAAACACTTCTTATTATCCAAATGCATGAGGGATGGAGAAAACTG
+GAAACCTTTGCAGAATTTTGGAGGGGGTGATGAAAAGTATTGGCAACACC
+TTGGTGGCCGAGAATTTTAAATTGATGATCTGGACTAAAAATTCAGATGA
+TGGCCGAGTTTTTCATATTCGCACCAATACAAATGATGGCCTAGAAAGTT
+TGGAGCGACCTAATTTTTCAAATTTACAAATAGATCTTTAATGTTTCATC
+GACAAGGGATGTGAACTAGAAATTAAGATGGTGGCCTAGAATTATATTTA
+TGGTTCGTCAAGAGGTGGCCTAACTCTTCAAATTCACGAAATATTCTAAA
+GTTTAAATTTCCTTTAATTAGTATTGTGGACTAAAAGTCGAGATAATGAC
+CGAACTTTTCATAAGCTCTCCACATCAATTGGTGGCCTTGAAATTCCGAC
+ATGGCCGAATTTTCGTAAGTCGACCCCAGTGGTGGCCGAGCCAAAAAACA
+TAATTCCGCAAACTCTTACATTTTAATATATGAGGGAAGCCAGAAGTGCG
+TGCCACATTATTTTTACATTTTTGACTATCGTGCCAAAATTCCAAAATCC
+TCAAAAATTTGAATTTCGCGGCACAATTTCGGGTTTTGAATATCTTTTTT
+TTAGTGTGATGTAGGGCGTACTTTCCAATTTGCATAAAATAAAAAATCAA
+CAAAAAGCCATACATAATGTCAAATGGTCAGTTGCAAAGAAAACAAACCT
+GCGGTCAGGATGGCCGAACCAGAAAAATCAATTCAAGCTTTCGATTTCGC
+CCGAAAAAAATGAGGATCAGAATAAGAAGGTGTCGCCTATTAGAGATTGG
+AGGATGTTGAGAAAAAGAGAATAGTGGAGGAAAATGATGAGGTAGAACGG
+AATTGAACATGCAAATAAAATGAATGTATTGGGTAGGAGAGGGAAGGTAA
+CACTGTGTGTTCTGTGTTTGGAAAAGGATTGAAGTGGTGGACAAAAGGAC
+TCTTGGTTTAATACTACTTGCCTGTTCTGATCAGGTTCAGAGGTATTTCA
+GCAATAGCTTTTGTATTTTGCATTTTGTCTTTTTAAGTACTATTATTTAT
+CAAATCCTTTTTTGTAACTTTGAATCTGATGTCAAACTTGTGGAAAGTTT
+GAACTCGAAGAAATTGCTCAAAAAGTAAAATTTGCGCCCAATTTTTCGAA
+TTTTTTTCGTTGTTTCTTTTTAATTTCAAAACACAAATCTTCGCCAAAAC
+ATTGTTACAAAATTAACATTTTAATTTTTAAACAGCTGCTAAAGCACTAC
+AAATGTGAAATTGATGCCTAAAATTGGAGAAAAATGGAGTTTTTCAAAAA
+AAATTGAAATAAGAAAGTTTGGAAACTAAATGTCTATATATGGGGAAAAT
+GCTATTTCGAATCTCGCGTTTTTTTAAGTTGGGCATCTCCAAAATATGAA
+AAAAATACAAAAAAAAACTCCAAAAGATAATGTTGAATTTTTTCAAAACC
+CTCACCAAGAAGTATGTTTTAATAAACAAAAATTTGAATTTCTTTTCGAA
+TTTTTTTCAAAATTCGTAATATAAGATACCTGTCACACTTATTTTCAAGC
+TAACAGGAAAAAATAAATGTTGAACTTTATTTAATGATAAAAATAGTTTG
+TAGAAAATTCGTAAATTTAAAAAAATTCAAATTCTACCAAAATATATTAG
+TTTTTCACCTGGAACTAAAAACATTTGAAGAATTTTTTTTAGCTTATATA
+ACACTACAACCGCAACACATTTTTGTGAGAACATGTCTAGCCTCTGTCAA
+ACAGTTTTCCGGTATCTTCGTGTGTGTGTTTGCTAGTGTTCAATAGATCT
+TCCTGTAAAAAATCGAAAATTTCCGATTATATGCTTTTTATGTGTTTGAT
+TCTATAAGCGTTTAGATTGTTATCAGATGATTTGACATTATTCGCAACAA
+TTTTTTTAAATCCGAATGTTTTTCGAATTTCTATTTTTTATAATTTTCCA
+GACAGTTTAAGAGCAAAGTTGAAGTTATTTTTTCCTATCAAAAAATGCAG
+GAATAAATACTACCTCAATTTTTGCAAGAAAAAAAATTTACAGTAGTTTT
+TTTGCTGGAAACTAAATTCCGCAGAATTTGAAAAATACTGAAAGGGTTTT
+TTTCCTTTTTTAATTTGTACTCCCTACAGTACCCCTTATTTTTGAATTAC
+AATTTGATGTTCGTACCTAAAATTGACACTTTTTCTCTAGTATATTTCCG
+AATTCAATTCATAATTATCAGTTGAAACTAGACCCCACCAAAATCACAAA
+TTGATAAGAAAACGTAGAAAGGGGAAAGCACGTGTAGCCTACAACAATAT
+TAACTGTTTTCAATTTATTATTTTTATTTTCCAAGGGTTTTATTCTTAAT
+TCTATTCACAATTTTTCGAAAAATATTCAGCAAAAAAGTATGCTTTCTGA
+CTATATTATCAGTATAAAGTGAGTTTTTTGTGAGCATTAAAAAAATCAAT
+TTTTTGTGGCCTAGCTTTGCATTTAGTGGCCTAAAAAATTAAATGCATTT
+CTTCCACGTTTTCCGTAAAAAAGACAGTGGAAGAGTTTTTATCCGTACTT
+GGGCAGGCTTAATATTTTGTGGCCAAATTTTTCGCGTGGTGCCTAGAAAC
+TTTTTTTACGTTTTTTCTCGGAAACTTATTTTTTTCCATGGCCGTGAACG
+AGTTTTGTTTAAATTTCAGGTCGCTTTCAATATTTTGATGACTAGTTTTT
+TAAAAAATATTTTCCTGCTTTTAGTAATGCTTGGCCAAACGTCTTCACGT
+GGTCGAGCTTTTCATTTGATGCCCTAGGATTTTTAACCTGTCGTTCTCTA
+GACAATAACTACCGTGGACTCGAAAGTTCTACGCCACGTTTTAAATATTT
+GTAGCCTAGAAATCAAAGTCACTTCCCGAGTGGCCTACGTTTCCCTGAGC
+ATAACTAGTCCTCGAGAAGTCCAGTCGACCGTTACTGTCTACAAGATTAT
+CGGCAAGATAATCCGTTTCGATTTCGATGTCCACTCATTCACTAGTCGTT
+TTGTCGTCGTTGCAACAATGTGGAAATTACTAAATTTTGGCATTTTTAAA
+GATTTTTAAACACATTTTTTCTGTCGGAAACTGAGAACCGCAGTTTGTAG
+AGAAAAAAATTGCATTTACTTTCCTGATTGAAAAATCTTTGTTAGCGTTC
+TTCCCCGCTGATTTATGTACCGTTTAAGTTTCAGCTGAGAGACAGCGTGG
+GATTGGGGGAGACGCAGACAGCGAGTGAGTTTGCGTCTCCCTCTCCCTCC
+CACTCTCTCATTTGCAAGTTTTGAGTTTTCATAACTCGGAGAGTGGAGCT
+ATCGAAAAATTCAAAAAAAAAAACAAAAAATTAAAATAAAAAAATTCTAC
+AAATTTTTAGTTGCTAATTTTTTGATAGCGCTGCTAGGTTTTGAGATAAT
+GACGTTTTTAACTCTACCTCGACTTTTTGTGTGTTACCAAGTTAGTATTC
+CTCTGACAAACCGCATGACCTCACCTCATTGTAGCCTCTTTCGAAATCTG
+TAAACTTTACAACTCATGTTTCCTAGTGATATCCGCCTCCATCTCAGCTG
+TTCTCTTTCCATCTTCTCCTAACTGTTTTCGTCTATTTTAAAAATGAGAT
+TATTCGGATTTCTTACTAGTTCCGCTCAAAAACCAATAAATTTATTTTGT
+AGAGCGAAAAATTCTACACATTTTTGTAGTCAACAAGTTTTTCAATGCAC
+CTCTCCTCGCTGAGTTTTTAAGATCTATAATTTGATAGTAAAAATATTTT
+TGACAGTAGCTTTTGTTTTAGAGATAATCAGGATTTCGCAAGCCACGGAC
+TTCAGTCTAGCCTCATTTCGAAAGTTGTGAACTCTGCAAGTCATGTTGAC
+TAATAGTATCCCTCTCCAGCTGTTCTTTCTCCTCCTTCACTCAAGTGGTG
+ATCGTTTTCTCACTTCTCTCGCTTTTTCGCCCCTCTCTGTAGTGTCCAGA
+GAGTATCAGTTATGTCTCCAGGACGCCGTGTGACGTCATCGCTGACAAGC
+CGTAGCCTACAGCGCCCGGCAGAAGACCTGTTTTGACATGCCATTCGTGA
+AAAATTTAGATTAGCCCTCTCACACTCTACATGTCTCCATGTTTTTTCAC
+ACAAACTATTTTTTTGAAGAAATATCTTTAAAACTTTGCTTTGTCTATAA
+TTGATAGCATAAAAGGTCCAATTTTTTCCGTAGCTCAGCAAATGGCGTAA
+CTAAATGGTGTGAAATGTTTGATAGGGGACCGGTTTTTGGCTGAAATCTC
+AGAAAAAATGGAGCCCTGCCTGCATAGAGACCCCTTTCGACTGATGACGT
+CACAGAGTAAGGTGTCACATCACACCATTCTTATTTCTCTATTTGAGGTC
+CAATTAGACTAGGGGGTCAGCGTGCTCTCGATTCCTAGCCGATGACGTCA
+CATATTTGCCATTCACAACTTTCTAAACTTCAAACATTTTTTAATTTTTC
+CCAAATTTCAGCCGATTCCTAATGGGAGGATTCCTCTCCAAACATCACCA
+CCTCACTGCAGTCCACGATGCCACGTGTGGCCCAATAAAAGGTGTCGGAT
+ATGAGCAAGTAGGTCATAAATTGAGCTCTCACTAAGTTAAGATGAAAGAA
+AATTATTTAGGAAGACGGTTCAGTGGTGGAGGGGTTCCTTGGAATCCCGT
+ACGCCGAGCCACCAATTGGAGCCTTGCGCTTTAAGAAGCCAGTTGCTCAT
+CGGAAATGGACGGAGCCGCTGGATTGTGTTAGGTTCGGGCCAAGGAGTCC
+GCAAAATGATGAGCTACTAGGGCAGGTGAGGCGCCTAAATCAGAGCAAAA
+CTCTGTCATTTTTATAATGTTCAGTTTGTGAACACAGTCGGGAAAAGTGA
+GGAGCACTGTCTCAGCCTGAACGTATTCACTCCAAAGTGGGAGTCAAATG
+AATGGCCCGACGGCTTCCCAGTGATGGTCTTCATCCATGGCGGAGGCTTC
+GCTGTTCACTCATCCAGCAACTACGGCTGCGCTTCCATCGCACGAAACCT
+TTGCACCAAGGACGTCGTCGTCGTGACCATTAACTACCGCCTCGGCGTCC
+TTGGATTCTTCACCACCGGCGACGAAGTGTGCCGTGGAAACCTTGGACTT
+TGGGATCAGACTGCCGCACTCGAGTGGGTTCAGGAGAACATTCAAAGCTT
+CCGAGGCGACCCTGATAATGTTACAATCTTTGGCCAAAGTGCAGGTGGAG
+CATCTGTGGATCTGCTTTGCCTATCGCCGCACTCGAGGGGATTGTTCAAT
+CGGGCGATTCCGATGGCAGGGAATGGAGAATGTGATTTTGCGATGCGGAC
+TAGTGAGCAGCAGGCTCAGTTGTCGAGGGAGTTTGCGAGATACCTTGGAT
+GGGAAGGAGATGGTAAGTGATTGAAATGTCGCTTAGTCGTAAGATGTTAG
+AAATTGCATTGTCATCAGAGTTGGATTGAGTTTGTTTAAGCGTAATTTTT
+ACTAAAGCCCATCGAAGCAGTTCCGTTGGCTACTTGGCCTACCACACTCA
+GCCTGGGAGCCCGTCATAGCAAGGCTCAAGACATTTCCTATGTAGTTATT
+TCTATTGCAAATTTAATACGGTGAATTTTCCAAAAATCTTGACGTATCCG
+AATGAAAAACCAGTGCAAACTTGTTGAGTAATATCCCTAATTACTTCATT
+CCAGACAACGACAGTGAAGACCTTCTCCAATTCATCGACCAGCAACCCCT
+TTACAAGATCGAGATGGGCATAAACCCGAAAAGAGGATTCAAGCATTCCC
+AGGCTGGAAGCTTGTATTTTGTGCCAAACTTTGACGGCGACTTCTTCCCG
+AAACCACTTAACCAGCTTAGAAAAGAAGCTCCAAAGATGCAAATAATGAC
+AGGAACCACCAAGTACGAGGGTCTATTTTTCAGTGAGTTTAAACTTCTGA
+AAATTTTCTGAAAATTTTCTATTATAGTCGCCCTCGGTGCCTTATCGAAA
+AATCCGGAAGGAATTAAAAAGTTCATGGGAAGAATCTTTAAAGAATGCGA
+CTATGGAGAGCGTGCTGACGATGTGCTGCAGATGGTCTACGACTTTTATT
+TCAAGGGGGTACATCCCAAGGATCATGAGAAGAATATGCATCAGATTGTG
+AAGGTAGGTGGCATAGAGCCTACAGGGCCATCAGCCAGTGTTTCAGTTCA
+TTGGAGACTATTCTATCAACTATGGTACATACCGTCTGGCTAACATTATG
+ACGGATCTTCAACACGATGTATACTTCTATCAGTTTGACTATCATAACTC
+TGCAGGATTCGGAGTGTTCCGGTGGCTTCTTCCGTTTTTGGGTGAGTTTA
+GGCAGGATGGGTCAGATTTTCTAAGCTCTGGGCCACATGCTTTTTGGTAG
+ATCAGTTTTAGAAATTCTAAGCTAGAAATGTATGAGTATGGTAAAACTTT
+TAAATCAGATTGAAAAGAAATTTTCCAAATTATAGGACTTTGTAAAAACT
+CCGATTGCTTAGGCTACTTCATCCGTACGACCGTAACCTGTCACTAACGA
+TTCTAATAGTGTACCTTATCTGAACAGTATTGCCGAACTAATTGAAATTA
+ATCCTGAGACTCCGAGATTACCTAGCGGTCCCTATCGCTGTGGCCCAGTG
+CCCATTTGGCTCAATATCCAATTTTCAGGCTCCACACATTGCACGGAAAT
+GAGATATGTGCTCGGCAAAGGAATAATCTCGAAATTCCGACCAAATGATA
+ATGATAAGAAGATGCTTCACGTTATGACAACTTATTTTACAAATTTTGCA
+AAATATGGGTACTTTTTTTGTGAACACTTTCGAAAAAAATTAAGCTGCTT
+TCAGAAACCCTAATGGAGAAAACCAGGAGACTGGAGAATGGCAAAAGCAC
+GACTCGGCACACCCGTTCCGCCATTTCAAGATTGATCTGGACGATTCTGA
+AATGGTTGAGGACTATCAGGAACGGAGAGCCGAGCTATGGGATAAACTGA
+GAGCATTAAATGTTAGCAGGGCTCAGATGTGAAATTGCTGTTATTTTTAC
+TTGATTGATTTTACGGGTTTATAAATATTTTTGATTTGTTATATATTTAT
+TTTTTCTGAGTTACATACATACATCAAGAAACATTTCAATATCTTGCAAT
+CTAACTGAATTTTATTTTATAATCAGTTATTTTTATTAATCCTGTACTAT
+GCCAAAAAATCTAACTTGTTTGAATCAATAACTCAACTACCAATCCTTAA
+CACAAAAACCAACACGGTTCTACCCAAACGATGTATAAGCTGGCACCATT
+ATAAATTATCCGCATACTTTTTCAAACAAAGGAAAAAGTCGGAAGCTTTC
+CATACATTCAACTCTATTATACTTTCCCCTTTCCATGGATGTGCTTTTTG
+TGTGAAACCAAAACTTAACCGCCAGAAAGCTTTTTACATAATCTATAACA
+GAGGTGGGCGGCAATTGCCGTTCGGCGAACATTCTGATTTTTTGGAAATT
+TTCATTTTTGGCAAATTGCCGATCTGCCGTTTGCCGGATATCAATTTGCC
+GGAAGTGTTTAGAGGGTTCTTTTTACGACGGAAACACTTAAAACTGTGCC
+TTTTTGAAAATATTTAATTTTTATTCTTTTTTTCGGCAAATTTGCCGGTT
+TGCCCAATTTGGCAATTCGCCGGAAATTTCAATTTCGGCAGTCTGCCAAT
+TTGCCAATTTTCAGAAAAAAAATTTCGACGCCCATCCCTGATGCATACCG
+TTTTTGACTCAATTTAAATAGTACACAACCTTCCACATTAATGTAGTAAC
+GGTAAGGTTGCCTAATTTGTTTGAACTTTGAAAGCCGCGCACAGCACCTA
+CAGTAATCAATCTCCTTAAAGAGTGTTTTCGCAATACCAAACATAGGAGT
+TTGTAGAAACATGAAACCGAAGGACAACACATTTTGAAACAGGTGTCACA
+TTTATGTATCTGCACTTGATAGCTATGCAGTCAATGAAGCATAACGAGAG
+ACATGTGTTCATTCCCGAATGGAGTCAATGAGTCATAAGGTTCTTCGTTC
+TCATTTTATTATTACAGGCTTGGGTCCCACATTGATTCATATTATACTTA
+CTTTTCAATTCATTGTTTTTTTGTGATTTTTTTTCATTAGAATAGTATTA
+TAATAATATTCTTCTAATAATGACAATCGAAATAGTTGCAAGTAGAATAA
+CGATTTGTACAGTGATGCCCATAATTGTGCATGTTTATAATGTTCTAATA
+TTTCAACGCAATCATGACACAAGCTCTATAGCATCTCGTGAGTTCATTTT
+TGGTGAGGTTTCAAAAAAAAAATCCTCTTGCTCAAGAGCCATACGTTTTC
+AGTTAAAAATTTCTTTAATAAAATATAATGCTCATTTCTCGAACGTTACC
+TGTTAATGTTAACTGCGCCTACCATGTCCGTTCAATCCCACTAGTCAGTT
+ATTCTTTGCAATTAAATGATAAACTTTAATGTCTAAATCTCTTCATGGAT
+ATCTCCATCTCAACCATCCATCGTTTTTTATCAACCATCATCATTCTCGT
+GTTCTCGTTCTCGGGGTCGCCTCCGCTTCTTCATCATCATCACCACGACC
+ATTCAAATCGTTCATCTTCCTAATCGACATATTCCCGCATTAAATTTCTC
+TGTTGGGTATCAATGACTACCCAAAAACGGTCGCATTTTCTGAAAAAATG
+GGAAAATTGATTCCTAATTTATTGGTTTTGACCGGTTGTAACTAACCCCC
+ACACACTGTTTTTTGATACTACCTACGTCTATTTTCGGCTAATTTTAAGA
+AGTCAATGATTCCTAATTGTCTTTTTTGTTATTTTCTGTGAAGTGAAGTA
+TCAAGATAAAATCAGTTTGCGTCTCGCTTCGATTTTCTCATTTTTCGAAT
+GCTATTCCCCCGTAGCAATATGGTTTTGTTATTACACATTTGCACTTTTT
+TGCTACCCTCCCAATTCTGACTCACACTTGCATTCCGGAGACTGCCTGAG
+AGTTAAAACTAAACATAATTGTTATATAATAAATGTCAAAGTTTTTCGCA
+AGCTGAAAATTTTTGCCAGCTGAATTATTCCTCCTTCAAAGGAGCATAAG
+TCTAAAAATGCTAGAGTTATTGGAAAGTTGCTAATTACAAGTTATAGAGT
+TTAAAATTTTGAGTAGTTTCTCGATTTACAATTTTTGAAGCTTTATTCCT
+TGCTCAAACTCGAGCAATGAGAGGCAGTGGGGACTCCCCCACTGGGGAGG
+GGAGAACCTTGTCAACCCACTAGGGAGGGGAGAACCTTGTCAACTTTAAA
+GCCACGTCCCTCTGCAGGGAAAAGATCTATCAAAAGGTTATCAACTAACA
+AAATGTGCAAAATTATACGCTCTACATTTTTGTAGTTAACCGTTTTCTGT
+TATCACAGTTAGTTTTTGTGAAACCATCAAATCTGTAGTTTCTCCATTAT
+TATTATCACCTAACAGTATTATTATCAGCTGATAAGTATCCTTTCTTTTT
+GGATAATCCCCTTGTAAAGGAATATACCATTGTCTTCATCTCCTTTTTCT
+GTGTCTACCCTTATCTTTGGGTCGCCATCTGCCTCTCCTCCCCGCATATC
+CCCTCTTATATCTTCAGAAATTCAGGTTCCAAGGAATATTCCGAAAAATT
+TTGTTTGGAAGGTGACATGTCCGATCAATCGCTGGTCCAGAAGGTTCCAC
+TACTTGGCTCGTGTTCTCAGGTGAGTATGCGCCTTTAAACATTGAGGGTA
+CTGTATGCACCATAACGCAAAATTGCAGATTTTATAGTGGGGCAGGTTTG
+TTCTACAGATAACCGTAAAATTTTTATGTCCCTTTAAAAGAAACTCGTCC
+GAAAAATTGATAATTTACGAGGAAAACAACTTTTAAAAATGTTTTTTTAC
+TTCAAACGATGCTCTATTGTGCCGAATCGCTTGTTGTTTAGCGGCGTTTC
+TAAATATTTATTTACTTATCGAAAATCTTTTTTTTCATATTTATAACTGT
+TTAAACAAAATCGATAATATTTATTTTTTCTGAAACTATTCTGAAAATTT
+TGAATTTCCCGCCAAAAAAATTTCGGAAAATTTTGATTTTTTTTGGCATA
+TTATTTTCTGATAGAATTTGAATTTTTGGCCAAAGAAATTCTGAAAGTTT
+TGAATTTCCCGCAAAAATTGTATTTCTGAGAGAATTTGAATTTCTTGCAA
+TTTTTCTGTGAAAAAACAATTGAAAATAAACGTGGTCGCCAATACGAGAA
+AACTCGGCCACCGATTTTTTTTTCGCAAATTTTGCATTCGTTGCTGCATG
+ACTGCCAAAAATTGGCGGCCGAGTTTTTTTATTCTACAGGGTTAAATTTC
+ACAGATGGCCGAGTTTTCTCAGTTTCACGGTCACAGGCTTCTAGTTTATT
+ATATTCATCTCCGCGGCGCGCGCACCGTACTTTCTCCTTCTCTACTCTCT
+CGTTGTTCAATCCCTCTCTCGGATCCAACCAACGCCCTCTGCGATTGTGT
+CATCATCGATTTGTTATCTCAAATTCCGTTTGGCTTTTCAATAACCGTGC
+CTTATTGTCTCAGGAATTTCAAATTTCCGGTCAACAATTCGGATTATTAA
+CCATTTCGAAAAAAATCCTTTAAATTATTTTTATTATAATGAAAAACGTG
+CGATTTTTTCTCGCTGGTGGGTCCTGGCACGACTGAAACTTTTCAGCTAC
+TGTACCCAGCATTGCTTTAGAATTTAAATTTTTGCCGGCAAATTAGAACT
+GCAAGATTTTTTTGTTAGTTTTTAATTATAATTGTTTGGGAAAAATTACA
+AACTTTAAAAAAACCTACCGTACTCCCAAGTACTGCAGCCAAGAAATAAT
+TTGTTTCGTGCCAAGACCCATTTTTCCTTTAAGAACTAGAAACCTCCCTT
+GTTTACAACTGTACTTAAAATCGAATTAGTTTGTTCGCTAAACATGTTTT
+TCGCGCGAAATTTCGCTTTACTTTCGAAAAATGTTTTTCTTCATTTTCGT
+CGGCATGCGCCTTTAAACTACTGTTTTTGAAACTTTCGAATGATAGAAAA
+AATTAGAAAATATTTTTAATTTTCGCTTTCGCCGGAATATTCGAAAATTC
+GAAAAAAAAACTAAATTTCATGGATTCTCAGTTAAAATTCACGGAAATTA
+AAACTTGCGTAGCGAGACCTCAACGATCACATTACCTATGCGCCTTTAAA
+GCTACCGTAACCCTATTTTTAATTAAAAAAAAAAGAATTTCCTTTTAAAA
+TCGCCGGATTTTCTCCGTCTCTTTTCCCATCTTTTTTCATCTTCGGTACC
+AATCATATGTAGGTGAGAATATCTCTGCACCCTCCAACGAACCCAACACT
+ATATCGCTGCGCACCGTCCTTCAACGATGTCATCTTCCTCCTACTTCGAC
+CCCCTCAATTTATTTCCGATTTCCTCTGATTTATTGATCTTTTTTCCTCT
+TTTTCATCATTTCTACGTTCTATAAAGCGAGGTTTATAGCCAAATGGACT
+CATTCAAACGATTACAATCCAAAGTTTTCACGTCAGTGAGCTCACTGCGA
+AAATCTGAAGAGAATGTGAGTAAAAAGCGGCGGAAGACGTAAAACATCTG
+AAATATTTTTAAAAAAATTTGTTAAAAGCCCCACATTTTCGAGATAAATC
+TAAATTTTCAAGTTTGTAGCAGCAAATTAAGCAAAGATATATATTTCAGG
+CCGACGAGCAGACATACAACACAAAACGATGCTTCATCCACGTCAATCAC
+TTATCGATCGCGATCGCCGTCGTCGAGCTCTCGATTTTAATTTATCAGGT
+AATTTGTTTGCCTGCAACTCAGACCAACGCTTAGTCGTCTAATTAGATTT
+CAACCATATTTGATTAGAAACTGAGCAAATATAATGGGGACATAATTAAT
+AGGCTTATGGATTTTATTTGATTTGACAATATGGATTTTCTAACCAAATA
+TGGTTAAAATCTAATCCAATATGGAGCAAATCTAATCAAATATGGCTGAG
+ATCGTGCCATATTGGATTAGATTTCGACCATATTGGATTAGATTTGTTTT
+CTAATGAAATATGGAGAAAATCTAATCTAACATGGATTTCTAATCTAATA
+TGGAGCAAATATAATGCAATATGGATTTTCTAAAAAATATGGTTGAAATC
+TCGTTGAATATGGTTGAAATCTAATTAGACGACTAAGCGTTTATCTGAGA
+AACTGGAAAAACCTAAAAAAAATCTGAAAATTTTCAGTTTTGTGTGGAAA
+AAATCAATGAAAAACTCAATCCTACAGTAATTTAAAAATTCTTTTTCACT
+AAAAAAATCAGTTCCCATTGAAAAAACAAACTGAAAATCAATTATTTCAG
+CTCTCAAATGGCAGTTGGGGCAATTCGGAGCACTCGACCGTCTTCACAAT
+CGCCGCCTTGCTCTTTCTGCTCGTCATTTTTCTGCTTTTCGTCGCGATTT
+TCTACCAAATCGGAAATCTTCTCATCCCGCACATCGTCATGCAGATTCTG
+CTCGTTTTGTGCTTCCTGGGACTCACATGTGCGACGCTTTATGCGCTTTT
+CCACGGTGCCACGTTTCAGTTGCTCGTCGTGGTTACAAATCCGCAAATCG
+CCGCTGATTCCATGGTAAGTGTGGTAAAAAATGAAATTTGTTTCCTTGGG
+AAATTCCTTCTTTTTCCTCAATTTTTCCTCATTTTTTTGCTTCCAAAAAA
+AAGACCCATTTTGCGAAAAAAATTTTTTTTTTTCATTAATATATGTATTT
+TAAATTTTCCAGACAATTCTCCCGGCGCCAATGATCACAACAAACGTGGT
+TTCCGGATTCCTAGTGGGCCTTCTCGTCATTTTCGCAGTCTCCTACTTGC
+TCATCGCTGTGCTGAATGTGAGCTTTTCCCATGGCGAGACCCATGTAACT
+TTAATTTTTGCAGACCTGGTGCATGTACGTCGTCATCGATAGTTACCAGC
+TTTTGAAGAGCCAGAAACTTCAATCTCGTACTCCGTCGGTCGAGGAGTAT
+TGTGCGCCGAAGACGATTCAACTCTCACTATACCCCAATCAAATCGTTCA
+GGCCACCGATTTTTAGTCTATATTTTAGACCATTTGTTGAATTTTTCTCG
+AAAAAATCCGGTAAATTTTTGTGTATATATGTCCCGAAATTCTTCACTTT
+TATCACATGTGTCAGGCTTTAATTTTTTCATACTTTATTTTCGAATTCTG
+TACAAAAATCTTTGATATATTCTATTTATTCTTCTCAATTAATAATCACA
+CGATCCATCTTTCCACCCGTCTCGCCACCTTTGCATCACATCTCGACACT
+CGAACTTTGGTTTTCCGGTTTTTTCGTTGACTTTATTGTGTAGCTGGCAC
+ATCCATAGCGCAAACGCCTCGCGGCTTTCCACTTTTGGCGGCGATTCTTT
+CAGATCTTTTCGGAGATCTTTGGCGCAGAAATCGCAGGGATATGTCTGAA
+AAATTTAGGCGTTTTTGTGGGAATCTTGAGCTTATTAGCTAACTTTTCCT
+AGAATAGACATGAAACTTCTGGCTCGATCCTTATCCTCGTCGGTAGGCTT
+TTCCGGGTAGTAAACCGACATTGTGTGTAGCAAATTCCACGTGGATCTGC
+CTGAAATTTGAAATTTTTGGTGGAAATTTGAATTAAAAGCGAACCGAGCT
+CATCCTTGTCTACTGGACATCCGTGCAACTTCGCTCCTGTGCTCGTGCTC
+GGCGTCGTCTCGGATTCTGCAAAGAACTAAAATAATTGAGATTTTTTGCT
+CTGGAAATCTAGGGAAATCACCTTTTTTCTTTATTTTTTCAGCCATTTCT
+CTGCCTTTTTTCATCATATCCTCTACACTGACGCATGCACGACACGGCTT
+TCCATCTGGACCGATTTCCATTCTGAAATTAATTTTTAAACTTGGTTTTC
+GTTTCGTCAGTTTTAGAAGCCGTTTTAGGGCGTAAACTTATGAAACTATA
+CATAGTCTACGACAAATCTATAGAAATGCATTAAAAATAGGTCAAAAATG
+TGAGAAATTGCGCAAAAAATGATGCAAAAACGAAAAAAAATTAACTAAAA
+ACAAGAAATGCAAGTGCGCTCCACTGACACGCGTTAGAGAGCGTAGACGC
+AGAGAAATCTCGAGATGAGGGAAATCGTGGCGCGCGGGAATCAAGCTTTT
+TTGAATTGTCTTGATTTTTAAAGCCCAAAAAATAGATTTTTGGCGGATTT
+TTGGTGGATTTTCTTGCTTTGCAATGTAAAAATTAATTATTTGTTGCATC
+TAATCACTTTTAACAGAGATTTACAATTTTTTTAGTGGTCTGAACCTGGG
+AAAATCCTTCAAAAATCAATTTTCCCTACAAAAATTCGTTATTTACCGCA
+TTTTCCGCCCAGCTGATCAAAAATTCTTCTATTTTCTCAATTTATTGATA
+ACACTCGCCCACCTCAAGCATTTTATCACCTGAAACTCGTCACACTTTAC
+AATTTGTTTGCAGAAATATGCGAAAATGAGCGTTACTCAGCTAAAAAATC
+TGAAACACGCGATAGCTCAGCTTCTGGAGTGGGATGGAACGAAAACGGCG
+AGAAAGGCAAGTTTTTGGTGGAATTTATCGAAAAAACCTGATTTGTTTTT
+TTGCAGAAAATCGTCGACGAGGTGGTTCTTCTCTATCACGCTCTGGGAGC
+GGAGGCATTAAGTGAGGATAACCAGGAGATATATGATTTGTATGATTTAT
+CTGCACGTATATTCAACTTAGCTAAGAAAGTTAGTTTTTTTTTTGTTAAA
+AAGTCGTAAACAACAAGTAAATTTAAAAATAAGCATTAAAAAATATTGAG
+GCTTATGAGAGCAAAAAATTCCAGGAAATCGAAGAAGCCAACCAACAATT
+CGAAAAAGAACGAAAAAAGGGCACAAGACGAAGCGAAAAACCAGTCCCAA
+CTCCACTTTTCGAGCTATCAATACAACATTTAAAACGTTGCTGTCAGCAG
+GGAATCGATCACAATCAGGTGCCATGGATAGCATATTGTCTGAAACTACT
+GGAATTTCCAATCACAATCACCGAAAAATCGATCGAAAACGAGATTTCCA
+ACGTGCTCCTATTGAGCTCCAACGCCTCACAGCTCCATTGGGCCGAGCAT
+GCTCATTTGAGCAGCTTATGGAAATGGATTTGGAGCCGTGTCGAGACCGC
+CGATATTGGGGCACTCGCCATGAGAAATTATATGGAATTGGCGGCGAACT
+TGCTGGAAAACGTGGATTACGTGGTTTTCGAGAAGTCGCCTATTGACCTG
+ATGGCGAAAGTGATGGGAACACTGAAGAAAAGTGTGGAAATGGGAAATCC
+CAAAGAATAGTGCGTGGAAAACGAGTTCTTGAAATAATGTTCAAAAAATT
+CAAATTGGCTTGGACTTAGGCTTAAGCTTAAGCTTAGATTTAGGCTTAGG
+CATAGGCTTACAAGGGAAGTATTTCAACTTATTCCCGGACTTCAGAATGA
+AACCTATGTCATTTCGAAGAAGACTCTTTAAGTAGGTCCCTACAAAAAAT
+TTAGCGGCAGAGGAGCACTTTGACCTGGAAAAAAGTCGCTCTGAAAACTT
+TTCAGTGCATTTTTTCACGGCTTTCAAGGCCCGTAAAATGGCTCCAAATG
+CGAATTTTTGTAGATTTTTGAAGATTTCTAGGATGCTCAGGGGCCGGAGA
+GCACTCGGAATTTTTTTTGGAATTTTTTAAAATTTTCGAAAAAATCTGAA
+ATTTTTTGAATAAGTCCATGGCAAAATTTTTCAGTGAATATATATATATA
+TTTTTTTTAAATTTCAGAAAAGTTGTCAGTTATTTAAGATCAAAATTGGG
+TGTTTTTACACAATGAAAATTTTTTTGAGATTTTTCGGAACTGCAAAAAC
+CAATTTTGGAAAAAAATCGGCACCCGGAGTCGAACCCCAGTCTTAAAAAA
+TATTAATCAAACTCGCTAACCACTCGGTCATTCAACGACAATTTTTCTTG
+TAAATGAAATGGATGACAAAAAAACGTGACTCTTTGATATCTACTTAAAT
+ATATAGGGACGTGAGAAATAGCTTTGGAAAAGGAGAGGACGCAGAGAAAA
+ATTTTCAGAGCGACTTTTTTCCAGTTCAAAGTGCTCCTCTGCCGCTAAAT
+TTTTTTGTAGGGGCCTACTTAAAGGGTCTTCTTCGAAATGACATAGGTTT
+CATTCAGAAATCCGGGATTAAGTTGAAATACTTCCCTTGTTAGGCTCACT
+AGGGAATGACCAGAATAAATGGAGCGATATTCAAAAAAAATATATTGTAT
+CGGAAAGCTGGCATTCTCTACTATAAGAATATGACTGAAATTTTTGCCCG
+TTCGGGCTGGAAATCTGAAATTTTTACGTCTGAAATTCTACACTGAAATC
+AGTGCATTTCCTATGGTTAACAGTGGATTTTTGTCTCTGGCGCCAACAGA
+AGTCTCACCACAATGGTGGAAGGGCGAAAACATCGGTTCGGTGGTCGAGT
+GGTGAACGCGTTCGCCTCTTGAGCAGAAGTTTGTGGGTTCGGTTCCCATA
+CATGGTTTAACTTTTGGCCTTTTTTATACAAAATTTTCAGAACGGGAAAC
+AAGTATTTAGAACATTTTTTTGAGGGTTTTACATAATTTTTTTGCTTTTT
+AATTGAACCATAATTACCCTGGAAACTTTTCAGAAATTTTAATTTTTTTC
+GAAAATTGTCACTTTTTTCTCCACCAAACCCATGAGAAAATTTGATCGAA
+AAATTTTTTTTTGAAATTTTTTTAAAAATGCATGAAATATTTTAGAGTGT
+CACAAATAACCTATTTTTCATTATTTTCAATGACCGAATCATTGATTCTG
+ATGCCTTATCAAGACGTTTTACCAAATCGATATTGGCAAAACATCTTGTT
+TTTGAGGCTCCATATCTCTGCAGGAAAAAATCGCACTAAAAAGTGATCAA
+CTAGAAACTTGTTAAACACAATGTGATCTAAAACATTTCAGTTGAACACT
+TTTTTGTAAAAAATTTCGTTGCCGAGTTGGAACCAATTGATTTGAGCTTC
+ATTATTTTTGAATATTCTAAATAGTTAAAGATCTATATCTTGGCAACGAA
+ATTTTTTACAAAAAAGTGTTCAACTGAAAAGTTTCAGATTACATTGTGTT
+TAACAAGTTTTCAGTTAATCACTTTTTAGTGCGATTTTTTCCTGCAGAGA
+TATGGAGCCTCAAAAACAAGATGTTTTGCCAATATCGATTTGGTAAAACT
+TTATTTTAATTTTTTTTTTTCATATTATTGTTTTTATATTGGGTCAAAAC
+GTATTTGCTCTGCTAAATAGTTAGCTGGCGCTAATTTTTAATTTTATTAT
+TTTCGTATTTTGATAAATTTCACTGAAATTGTCACTTTAATAGTTTACAT
+TCTATTGGTTTTCTTTTATTCAATGTCTTTTGATATCGGAAACGTGATGT
+TTGCCTTGCATCGTCATTTTCCCAATCCCCTCCCATCAAATCCCTCGATT
+TCGAGACATGAGCAGAAGGTGGCAGATCATTTGGCAAGCATTATAAAGGA
+ATCTTATTATGGAGATACCAGTGTGGAAGAATCCGAATATTTGGTTCAAG
+AAGAATATGGCGATTGGGAGCCAGAAGTTTTTGAGGTATGTTGGTTTCGA
+CACTATTAATTGTCATTTAAAAAACCTTTCAGCCGTATGACTGTGTGTTG
+CCGGATCAAGATGATGTATTGTTCGGTGAGAAAGCTGTATCAAGGGAAGA
+GTTGGATAAAGCGATCACCTTCTACCGTAGCGGAAAAATTGGAAGTAGGC
+CGATAACGACTATGCACCATAGTTATCGCTGGATACGAACCGATGCTCAT
+ATGAACAAACTGCGCAAGTACGAGAAAGATAAAAAAGCGTTCCAAGAAAG
+CGTGCGGGTTCGTTTGGCACAGCTTACACAACGGCTTTATGAGGAGGTCA
+AGGAGAAACTTGATAATGGTAACGAACATTAATATAACAAGTTTTAATAT
+AAATATTTCAGGAGTCAATTTGCATGATTCTGATTTGATGGCTATGGCAC
+TGGAAATCAACACCCGCGAAATGAAGTTGCAAAAACAAAACGAAATGAAG
+TTGCAAAAAGCGTCACAATCCTGGATAACCCGATGGAAGCAAAGCCACAG
+GTATGTAATAAATTGCGGAGTATGTTAGATATATATATATATATATATAT
+AATTTCAGAATCGTGAGTCGGAGAGTCACCAAGTTTGTCACACGGAAGTG
+CCTGATCAATAAAGACGCTATCAAAAAAAACGCGGATGATTTTGTCAAGA
+ATGCCAGAACAGAGATCTCCAACTATCACCCGTCGATGGTCTTCAATTGT
+GACCAAACCGGAATTCAAAAGGAGCTGTATCCAGCCCGGTCTTTAGCCTT
+TATGGGCGAAAAAACAGTCGAGAGGTTGGCGCAATCGAAATCGTCGCTGA
+CCCACTCGTTTACGTTTCTCCCGATGATTTTCCTCGATGGCTCAATGGGA
+CCCAAGGCGTTTATGGTAATCGCTGAACCAAAAGGCCAGTTTCCTCCGTC
+TCGTCCAATTCCAAACTGCCCAAATTTGGAAGTGCGGGCTGGATACAAGA
+CACACATCATGACGAAGCAATTGATGTGCGATTTTTTCGAAAGTTGTGTC
+TTCATTCCGTCTGTACCGAAAAAACTGTACATCATGCTGGACAGTTGGCC
+AGCGTTCAAGGACCATACAACGATCAAGAACTTGGTTCCCAATGGTCATG
+ATGTCGTCATTCGCAACATTCCAGAGCACACAACTGGAATGATCCAACCG
+TTGGATGTCTATTGGAATGCGCCATGGAAGGTATGAATTTAAATCTTTAT
+AACTTTTTGATAGTATTTTCCAGAGCTTGATCAAGAAGTTCACAGCATAT
+GCCCTTCGAACCCAGACGGATTACGTCATCGCACAGAGGAACAACGCAAT
+TTGCATGGTATCTGTGTTGTATCACCAGATCTCGGCAGAGCACTTCCGAC
+CGTTTTTACAGCATTGTTGGAAGAAAGCTGGATACGTGGGTGCTGCGAAT
+ACTTCATCAACACCATTTTTGACTCCAGCTCAATATTGCATTGATCATGG
+TGACACAGTGATTTGCTATCACACTGGATGTAACCATCTCGGATTCATCC
+GATGCGCAAGATGCAAGATGTTTGTTTGTTTTAATCATTTTGTTGTGTCA
+AAACAACATCTTTGTTCATCTCCTTGAATAATTAATAAATTCATGATTGC
+ATTACATTCAAGTTTCGCTATGAATAAAATTGTTTATATGAGGGGATCCA
+TGGTTGTAGTGGTCCATGGTTAAGTTTAAATTTTAGGGGAAAAGATGTTG
+AATGAATCATTATGGTGTTGGTCGACACATTGATCATGCTGATATCGATC
+AGAAAAATTAAAATTTGGGCTTTTATATAGTTTCGAAAAAACACGTTTAA
+ATTTTTGAAAAACTTTACGTTAGGGTGGAATTGAACCCCAGAGTCCCACC
+ATGCTTGTCATCCACTCTATCCACTCGGCCATCTCGCTGTTGCAGGCAGT
+ACTAATTGGGGATGGTGATAAGTAAAGCACGTCAAAACGAATAATTTCAG
+ACGTAAAAATTTCAGATTTCCAGCCCGAACGGGCAAAAATTTCAGTCATA
+TTCTTATAGTAGAGAATGTCAGCTTTCCGATACAATATTTTTTTTTTGAA
+TATCGCTCCATTTATTCTGGTCATTCCCTAGTCAGGATCAGCCTCAGGCC
+TAGGCTAAGCTTAGGATTAAGGGTAGGCTTTGGCTTAGGCTTATGCTCAC
+GCTTAGGCTTCGGCTTGAGCTCAATCATACATCTTGCTTAAGCACGCAGC
+TTAACAGCAAAGCTTAAGCACACAGATTGGGCTTAGGCTCAGGCTCAGGC
+TTAGAAAAAGTCGAAAAGTTAACTAAGTCAAAAAATTTTATTGTTAAAAA
+ATTGTTTAAAAAGTATTATGATTTTAATAGAAAATTGGAAAAAAACCGAA
+AAAAAATGAACATAAATCAAAAAAAAAATTTTTTTTTAAAGAAAACTTCT
+TTTTTTTGAAAAAAATGCAATTTTAAGGTTTTTCTGAAAAAAACTGGAAA
+ATACTTTGATTTTACTGTAAAGAGAATTTTTTCTGTTTTTTTCCAAGATT
+TCAACTTATTTCTGCGAGTTTTTTTTTTCAAATTTCCTCTTATTACAGTT
+GGTGTCATTACCGAAAATTCTCGGTCGTCCACATTCTCTCATATATCGTA
+CATCGTTGGGGTCTCGAAGCGAGAGATTTCATTCTTCGTGAGATTTTCGA
+GCTCACTGGTAGTTTGTCCAACTTGATATCAGTGGCTCATAAGGATGGAG
+AACAGTCCAAGGTTTGAGTTTTTTTTTCTGAGTTTGCAAACGCGCCCTAA
+TTATAAAAATTTGGAAAATTCCACGTGGAAAATAGTTTGGCGAAAGTTTT
+TATACAAATTTTTCGTGGAAATTAATTTTTTTTCGAAATTCTCTTTTAAA
+AAATTTAAAAATGTTTTATTGGCGTATTATTTTTCTAAATTTCAGTTTTT
+CGCAGATTTCACCAATAAAATATTTTTTTGAAAAATATCGCTTCGAGACC
+CAAAAAAATAATTATGATTTCAATGAAAAATTGAAAAAAGCCAATGAAAT
+CGAGAAATTATCGAAAATAATTCGAAAATTGGAACTTTTTAAAAATTTTA
+AATTTTTTTCAAAACAAAAATAGTTTCTCAACTTTTTGCTAAACAAGAAA
+TATATTTCGTGGCGAGACCCATTTCTACTAATTTTCTTTTTCAGAAATGC
+ATAATGCGTTTGATTGATGATCTCGTGAAGCTCGCCATGATCGAAACCGT
+ACACGGCCACCGTACCATGAACGAAGTGACACGTGGAAATATTCAAAAAC
+TCGTGAAAACCGGAATCCAAGAGTCTCTGAAATCGGCGCACCGAAATTTC
+TCAAGGAGTTCGACATTTTCGATTTCCGAAGAATGCGTGAGATATCTGAC
+GAGATGGTTGTTGGCCGAACGAAGACTTGAACAGCCGTCTGCGGCTATGA
+ATGAATCGTTTGAATTGACCGGTGATAGCAGTAGTAAGAAGAAGGACGAT
+GCCACGTTTGATAGTGCGTAAATGGAATTCTACCAAAAGGAGATCTACAA
+AAAGAAAATCTACGAAAATAGGATTTGGCACGGTGCCAGATCGATCTTTT
+TTCGGCTCAAAATTGGAAAAACCTGCAATTTTTATACATTTTTGGCTTCG
+AAAATCAGGGAACTCTGCAATTTTTGGCATTTTTCGCTAAAAAATTGGAA
+AAATCTGCAATTTTTATACATTTTTGGCTCACAAACTGGAAAAACTTCCA
+ATTTTCATCTCAAAAAATCGGGAATATCCGCAATTTTCCTCACATTTTTA
+GCTTAAATAATTGAAAAAATCTGCAATATTTTACATTTTTGGCTCAAAAA
+ATCGGGGAATTTTGCAATTTTTTACATTTTAAGTTTAAAAGTGGAAAATT
+GCAAAAATCGGCATAATTTTGAACGTTTTCTTTTTTCCGGTTTTCCGTTT
+TGTTACGATTTTCGTTTTGCATGGAAAATGCTTCGATTGATACCCTTCTT
+TCGGAAACGAGTTTCTCCTGAAATAGGCGTAGTCTCAAACCATTTTATGG
+GCGTGGTCTTTCTCTTATCTTGTTTTTATAAATGTTGTTCATTAAAACAT
+TTTCAGGCCTTATCGATCTCTCCTTTGGCTCGACGATTTCCGGAAAACAT
+AAATTGAACGCGTGGAATGGTGTAATGCAAATCCTGAATGAGCTCCTAAA
+AAGTCGACGACTCGAACTTCAAGTCACTGAAAAAATCGTGACAATCCTCT
+GGGAAAAGCGAAAATCCTACACAACGGAGCCACTCCGTACTGTGTTCTGC
+TCCATTCTCTCCACAGTCGTCTGCCAGGCCGATGTTCGATTCGGTCATCG
+GAAAGTGCCGACAATCGACTCGATTCTCAAATATTCGCTGTCTCTAATGC
+CAAATGTCGCATCTCTTCCCAGTGCCGCTGCGTTGACCGAAACGATTGTC
+AGATTCAGGACAGTATCACGAGAGGGTCTCCGTAACACGTGGGATACCGT
+ATCCCGAACTAGCTCCGGCTCATTTGAAGTTGTTCGGCTGATTTCGGCGT
+TGATCTCCGTTACGGAATTTGATGAGAATTCGAGATTCGCCAACGATGAG
+AGAGTTCGGAGTTGGAGGTAAGTCACTATGCCACGTGGATGGATTTCCTT
+TAAAAAGAGTTTTTGGAAAACAAATCAGATTTTGTATATCACTTCACCTT
+TAAAGCGAAATTCTTGTTTTTTTGCAGTTTTCGAAAAGACATAATCGAAT
+GGGTATTGCTGGATCCGAATGCACATAGTCACAAATTACTCTATCAGTTG
+TGCCAGTATCATCCAACGTATTGTTATGAATCAGAAGCTTCTTCTAGTGG
+TTAGTTTATTCCGTAGGGCTTCCATGGTAGGCAGGCGCGATTTCAGGGCC
+TGACGCCTGCCTGAAACCTGCTGACCTTTCGCCTCTTTTCTCTCATTGCT
+ATCAATTTGTTGAAAATCAAATTAAGAAATTAAAAAAAAAGTTCACGTAT
+GTTTTGTCGTGGATTGAGGCGAGGGGCAGGTGGTGGTGGTCTTAAGGTCA
+GGTAGGCAGGTGTTTTCACGCCTACATTGAAGCCATAGTACCCCATATGC
+CGAAAACGCTGAAGTTTTCTCATTTTTCCAGACGACTCCCTGCTTCAAAC
+TCTGAAACTATGTAAATTAGCTTGCTCTCCAGCTCCCCCATCGGCTCCAA
+AAGCCCTCCGACCACTCGAAGCTTCAATTGAAGAGATTGTGAGATATGTG
+CATGATAAGCTCAAGAGCATTCTCGGTGAGCATCGGCTGTCGTTTTTTTG
+ATTTTTGAATTTTTAAAAACATTTTCAGCGACTGAAATCACTCTGCCTGC
+ATTTGTGCTCTGCCACGAATTTGCTCTGAAGTATCCGGATAGATCTTATG
+AGTTTAATGTTGGTTTTTTTTTCTAATTTTCGAAAAATTTAAGAAATTTT
+AGGATATAAATAGAAATTGAAGAGAATTTGAATTTTTAAAAAATTTCGAA
+TTTATGGAAATTCAGTAAAGTTTGTCGGAGTTTTTAAACGAATTTTCAGA
+ATTTGTAATAAAAACTAAATTTTCTAATTTTTTTTCCACAATTTACAACA
+TCTAAAAAACTTTTTAGAAATGAATTGTTAGAAGTTAGAATTCCTGGAAA
+TTAAAAAAAAATTTGGATTTTTTTAGAATTCTTAAAAGTTTGATATTTTC
+AAATGATATGAAGTTAACACATTTTTTAAAATATTCAAAATAAGAACATT
+TTAATTTTTTTGAAGAAATGTTCAAAAAATTAACATTTTTTGGGACTTTC
+AGAAGTTTCTTCTTTTTTTTTGCGTCTTTCAAGATTTTTTGCAATTTGCG
+TAATTTTTATTAAGGGGACAGAAAATTCTGAGAATGCGGATTGCACAACA
+TATTTGACGCGCAAAATATCTCGGAGCGAAAACTACAGTAATTCTTTAAA
+TGACTACTGCTAAAATTGAGCATAAAAATAAAAATATATCGATGTATCTT
+GGATCCCGTAAATCGACACTAGCGCGCTACAGTAGTCTTTTGAAGAATTA
+CTGTAGTTTTCGCTACGAGATATTTTGCTCGTAAAGTGTGCACGAATTCT
+TATAATATTTTGTTCTCACAAAAGTTGGTCAATTTATGGGATTCTCAAAT
+TTTCGATGTTTTTTTTTTTGAAATTTAAGATTTTTAAAACATTTTTCAAA
+AAACTGATTTTTCTCTTAAATTGAAAAGGTTTTTTTTTCAGAAAATGTAC
+AAAAAGCTCTACCAAATCATGGAAGATCAAGAAGAAGACGAGTTTCTCCA
+ATCAGCTCGCCATTTCTCAAAATGGCCTCAAAATCTGACACTACCAATAC
+AAAAACAGACAATAAATTGCATGGCTGTCTTTTTCGAAGCGAATCTTGAC
+AATCAGCTCGTCGATCTCTGTCAGTGGAGTGACCGACGAAAAGTGCTTGT
+CGAGATGCTCGCCGAGCTGGCCGCCACAAGATCTGAAATTCGAGATAAAC
+TTCAAAAATCGATGCCGTTCAACAAATTCGTCAAGGAGTGTATAATGGAG
+AATCGCGGTGATTTGTATGAAATGACAAAGAGATTTGAGAAATATTCGTT
+TTTGCTCTCGATTCGGAATTTAATTGTTACTAGGATGATTATAACGTGAG
+TGTTTGTTTTGGGGATTGCCACGAAAAACTGGAAAAACGTTTCGAAAATT
+CAAAAAATATTTCTTCAACATTAGAAAGAATTTCCATTTTTTATATAATT
+TTGGAAAGTTTTTAGATTATTTTAGATAAAAAATCATTTCGAATTTACAA
+AAAAAAATTATGAAATTTTAAAAACAAGTTTGAAAATGTATTTTTAAAAA
+ATTTAAATATTAATAAAAAATCTTGTTTGAATTATTTAAATGTTTGCTAT
+TGTGTTTTAAAAAAGCTTAAATTAAAAATTTTTTTCAACAAATGACTAAA
+TTAACAATATATAACAAAAATTCAAAAAAAATTGTTTTCGAGAAAATTTT
+TTGCTTTTTTTAAAAATAAAATTATAAAAAGAAACAGAATAAAAATCGAA
+AAAAAAACAATTATTTTGAAATTTTCAAAAAAACTAGAAAAATGTAAAAA
+TTTTGAGGAAAAAAATTCAAACATCCCAATTTTTGCAGAAACGAAGCCGC
+CCGACTCCTAGGAGATGGTGAAACAATCAGTGAAACCGATATCTTCATAA
+TCGAAAAGCGTACTCTTTCCACGTGTATTCGTAATGTGTCCGAAGGAAAA
+GAGTTGAGCGGCTACACACTGGACCCCTATACGGTAGCTGCCAACGTGCA
+CAATGTGCATTTCGATCACATAAACGTCGAAATCTATCTGGAATTGCTGA
+AAAAGTCGCCATTTTTCGCTCAGAACATTGTACGCCACTTGTTACGGCAG
+AATGGAAAAGAAGCAGAAGAAGAGACGTGGCACTTGCATGCCACTGTGCT
+GAAAATTGTGATGAAAGATGAAAAGTTGCTGGCGGTAAGGAATTTTTTTG
+GAAAAACTTGAAAAAAAAGAATTTCATCGTATTTTTAAATAATTTTTTGA
+ATGAAAAATTCGGTACTTTTCCTTTTCTACCCCGCATTAAAAAAATATTC
+AAACTATTGACTTATTCGAATTTAATTCTCACGTGAATGTTTGTATTAAT
+ACTATTTTCATTTTTAGGCTTAGAAAACAACAGTACTAAGCCTTGAAATA
+CAGAAAAAGAAAAAGAGTTCACGTTTTTATCAATGAAAATATTCCTGAAA
+AAATGCGGGGTAAAAAAGGAAAAGTACCAAAAATCAAACTTTCAAAGTTA
+ACAATACGCAAGTTTTCAAGTTAATTTTAATAATGGATTGTTTAAATCCG
+GAATTAAAAAAGTGGTTCAAATTTTATTTTATTTGACTCTATTGTGGCGA
+TTTTCATGACAATTGAAACGATTTTTGAAACTTGTATTTATTGAAAAAAA
+AGTTGAAGCAGGTCGTAATTTTAATTTGAATATTTAAAAAAAACTTATAT
+GGGTGCTTCAATTTTGCAAAACATTGCAATTAAAAAAAAAATTTTCAAAA
+TGTGGTCGGCAAATCAGAGTGTTTGAAAAAAATCCTTCTAATTGTGTTTC
+CGGAATTTTTGGGATTTTTTCTTCGAAAATAGGAATGGTTTAAATTGAGT
+TAGAAATTTTTGCAAATAAAAATCGGTTTTTTAAAATCAATTTCTTGCAA
+TCAAAAAATTGAAATTTTCAGCAAAATAATAAAGTTTTCTCTAATTTTTC
+AATTTTCAGGTATGCGTGGCCACAATTCCAAATATGGTTCGATATCTCAA
+AGTCTATCAGATTCATTTCAGTCCGAAATCCAACGCGGCGAAGTTCTTGT
+AGGTTTTGTAACTGCGAATTTCAAAATTTTGCTCGTCTAATTTGACGCCT
+GCTCTGTTTTTTTTTACGCGCAAATCTTAGAAATCGGTGACTTTTTCGTT
+TAAAAACACCATTTTTCAGTAAAATCTGAGCAATTTTCGGTTTTTGCGCG
+TCAAATATGACTAATTGAGTCAAACTTGACGCGCAAAATTTTCAAAAAAA
+AAATTCAATATTTTTCCAGACACCTCGACATGGAATCGATTTCCCACTGC
+CAATCATATTTGCGAAAACCAACAAAATCATCCAATCTGATCACGGCCGC
+CAACTTTTTGACACTTTTCGGATGTGAAAAGCGCACGTGGAAGCGCCCGA
+TTCTCAGATTTTGGAGCATTTTCAAGCAGCAACCGGCTATGTGTTGCGAG
+AAATTGCTCATTTTTGTAAGCAATGATTTTTTGATAAGAAATTTCCCAAA
+AATTTTGAATTTTTGAATTATTTTTGTTAACTTCTTATTTTTAACTCAGT
+ATTTTTGCAAACTGAAAATTTCCAATTTTTGGGCTTAAAAAATCTCCATT
+TTTCAGGCTGAAGAATGTGTCGAACTTGGCCTGAACCACCGAATCGCTTG
+TCTTTTACGCGCACTGACAACCAGTGAATTCTGCCGAAAAGCTCTATGTG
+ATGAATATCTGAAAATCGCGTTTCAGCTGACTTATCGATCGATTTTTCTG
+ATTTTAAGCAAAAATGAGTGCAGGTTGGTGGAGAAGGATATGTGGAAAAA
+CAATATTTGAAAAATAAAAAAAAAACTAATTGATTTGAATTTTCAAAAAT
+TCCAAAAAAATAAAGAATTGTATTCCAATTTTCATGAAAATGGCAACAAA
+AAACTCAAAGTTTCATTGGAAAATTTTTGAAATTACAAAAAAATTAATTT
+TTGAGTTTCAATAAAGTTTCAAAAGTTTAGTTTGAGTAGTGTTGTCAACA
+AAAATTGAATGCCTATTAGAAATAGTTGAAAAAATTGGAATTTACAAAAA
+AAAACAATTTTTAAACTAATTTCTCGAATTTCAAAAAAAAAATCTTCTAA
+TTTTTGAAATTGAACAATTTGGAAATTTTTTGAATTTTCAAGAAAAATTT
+TCAATTTTTCGAATATTCAACAGTTCCAAAAAAAAATTTGTTGGATTTTT
+TTCCAATTTTAAACAAAAAATTTTCAAATTTCCACAGATTTTTTTTTAAT
+TTTTTAAATTTCAGAAAAAAATTAATTTTCATAAAAAATTGAAAATTTCC
+ATTCTTCAAAAATAAGTTTTCACATTTTTCAGACCAGAAATTGTGGAGCT
+CTGCGATGACATGAATCTTCGGTACGATCTTCTCCAGCACCAGATCAAAC
+ATGTCGCGGCTCACCATTTGGAGCACTTTGAGCGTTTCGAAACGAAAATC
+GCATTTTCTGTTGAGAAATTTCTGAAATCTGGAATTGATGGAATCGATTT
+TGAAGATTTAGGATTAGTCGAGTTTTATAAGCAGTTGAACGAAAATTTGA
+CAGAAGACGCGATCAGGAGCAATGAGGCGAGAAGTAAGGCCGTGGAATAT
+AAATTGGTGGCCGAGTTTTTTGTAAACTATGCCACCAAACTTGGTTTCTC
+CGTTCGTGGCCACAAAAATTTTGAATTTTTTGAGCTTCTCTTATAATGTT
+TAAAAGTGATTTCCTGGCAAAAATTCATTTCTTTAATTAGAAAATTCCAA
+AAAATTTGAAAAAAAAATGTAAACTCAATAAAAAGTCTAATTGTTTCAGA
+TTTATTCTGGTTTTTATTGAATTTTCAGATTTTTTCTTCAATTTTCAGTT
+TTTTTCGACTTTTCTAATTAAAAAAAACCAATTTTTGCCAGAACAAAAAC
+CATTAAAAATCGACAGTAGTCATCCCATTGGAGTACAAAAATTTTAATGT
+CCAAATTTTCATGACGAACGAAGAAACCTAGTTTGGTGGCCTAGTTTCCG
+AAAAAACTCTGTCACCAATTTCTTTCAAAATTCAACAAAATTTTAGTAAA
+TTCCAAAAAAACGAACATATTCGGCGAAAATTATTTCAAAAGCTTCCGAA
+CAAAATCTAAAAACGTTCAGAAAGTTCTGGGTAATTTTTTAAATATTAAA
+AAAATTCAACAAAAAAAGGGGGGCAGATAGCTCAGTCGGTAGTGGTGGCC
+GCTAGCAGTCTGGAGGTCACGAGTTCAAGTCCGGCCTCACCCCCTAGGTT
+CACCCAGCCTCTATTGGGAAGTGGAGCAATCCACGACTGGATTATCGGCC
+ACAGTCCCCGGCTAGGACGTGGCTTAAATTACAGCCCAGAGGGATCACCA
+CCAGGCAGTGTACCTGAATCCCAGATCCGCAGTGCATAGCACTTGAAGAA
+CGGATCGTCCTTTAATTCTTTCAAAACTAATTTTTTACTAAAAAAAATTT
+CCAGACATCTACATCGTCGACATTCTCTCAACAATTTGGCTCCAGCTCCC
+CTCAATTCGTCCTCAAATTCTACCGATTCTCGCCCGCTTCAAGCACATTT
+CCCCAGCGTGGACTAATTTCCCACAGCCGCCTCATATTTCGACAAACGAG
+AAATCATTTCTTCAACATCTACGATTTCATCTTTATCTAAAAATGATGAA
+TATCTCGAAATCCATGACGCAAGGCGAGTATGCCACGTGTATTATGATGC
+TCCTGACGAGCTACGACTCGAGCCATTTCGTTGCGGATTTGATAGAGAAA
+AAGCAGCTGGGAAAGCTGAAATTGCAGCAGAGAAGGAATGTTTTGTGCAT
+TTTGAGCCGACTTTTGAAAGATCAAGCTGTGATGGGTGATGAAGATGAGA
+CGATTATCGATCCGATTCTTTTTAAGGCAATCACCAAAGCTTCCGCCGTT
+TTTGTACGTTTTTATACGACGGAAATCACTGAATTTCATGTTTCTATGCC
+GAAAAATTATGAGCAATTAAATATACATCACAAGAAAGAAAATAGTTGCC
+GGTTTTTGAATTTTTCTGTCATATCGGCAATTTTGGCAACTGCCACTTTT
+TGAAGTTTTTAAAAATTTGGTAAATTTGGCAATTGCCAAAATTATCTCTG
+TTTCGATTTTTTTCATCAGAATCATAATATTTTAAATTTCGCGCTAATTT
+TTTTAGCAAATGATCTTCGAAAATTTAATGTCTCGCAGTTAAAAATACAT
+CTTTGCAGGAAGACACCGCCGCGTGCATCGTACCATTTTTGTTCAAAATT
+TGTGTGGATTTCAAGGGAAAATACGATAAATGTGTGATAAATTTGCTGGG
+ATGTCTTAAGGGAGTTAATGCAGGTATGATTTTTCGTCAGAAATGACTGG
+AACGAGTTTTTCGCATCAATTCAAATTTAATGTAATGGCATTTGGCATAT
+GACATCGAATGTCGAATGCTGGGAATGCCGAATAATATATTTTGGTCGAG
+TAGGAGAATAAACTAGACAAAGTTCAAATATATTCCCAACAGGGATGGCT
+TCACCCGTGACCCGTTTCACCCGTTCACCCATTTTTACAAGGGAAGGTTC
+TGAACTCGTTATCGGACTTCGTTACGCCACTATATACATTCGATAGAGAA
+TGGTTACAGATGATCACTCCAAAAAATTTAGCTGCTTCAGAGCAGGTTCG
+ACCAAGTTACGACACTTTGAAGATGCCGAAAAAAAAAATCATTGATGCAC
+CCCCTTTGAAAAAAATTGAAAATTTTCACTGAAAATTTTTTTTTTCTGAA
+AGTTGATAAAAATAGTTGTAATCGATTTAAATAGTAAAAAACATATATTA
+TACAAGTTTTAGCCCATCACTCTCAAAAAAACCCTTAAATTAATGTACAT
+ATCTTGAGAAAAATTCCAAAAAGTAGATGTTCATGTAGATCAATTTAAGG
+GAGAATTATGAACTGAAACTTGTATGGTATGATTTTTCCATCATTTGCAA
+CTATTTGAAAACATTTTATATCAACTTTTAGAAAAAAAATTTTTTTTTGA
+ATTTTTTGGAATTTTTAAAAAGGGGTATTTTGGCACTTTCAAAATGTCGT
+AACTTGGTCGAACCTGCTCTGAAGCAGCTAAATTTTTTGGAGTGATCATC
+TGTAACTAATCTCTAACGAATGTATATAGTGGCGTAACGAAGTCCGATAA
+CGAGTTCAGGGCCTTCCCTTGTTAGGCGTTTTTACGGGTGACGGGTGACC
+CGCTCGCCCGTTTTTTTTTTCGTTTTAGTTGTTTTCACGGGTGACGGGTG
+GCTCGCTCACCTGTTTTTCACCCGTTTTTGGAAGTTTTCACGGGTTATGG
+GTGATCCTTGGTTCCCAAGAGGCAGCCAGTTTAGGTCAATAGGTCGTAAA
+TATCGTTTTGGGCCACGTTTACAACTGGGCTGTGTGCAACTAGAGGTGCA
+CTTGGGTCGAAAAGGGTCGACCCGCTCCAACTTTAGGTAGCATTTGTAGC
+GACCCCGATAAATAAAATGTCGACCCCGAATGAAAATTTTAGCAAGGAGG
+CCATGCTCGTTTAATTTCCATTTTCAAAATTATGATCGGACTATTGGTTG
+AGCTACTGTGAAATAAGCGGGTCGACCCTGCTCGACCCATGAGCACCCCT
+AGTGGCAACCATGATTTTCGGCAACTGGCAATTGCCAGAGTTGCCGAACC
+CAATAAGTTTCGGCAACCGGCAATTGCCGAAGTTGCCGAACTCTAAAAAG
+TGCAACCGGCAACTTTTGCGCAGCCCTGGTTTACAACTACCTAACGACTT
+TTGGTAGACTAGAAATAACACATGTATTCGAATTCGACATATGCCGAATG
+CCGAAAAAAGTATTGAACGACATTAGGCACAGGGATGGGCGGATACCTTT
+TCGGATAACTTCACTAAATCAATTTATCAATAAGTATTGATTTAGTTATT
+CTGGAGATACTATACTAGAATAAAGAGTACCTATTGAGCAACATTTTCAT
+ATGACAAAAACTTTTAAAATTGTACGCATTTTCCTCGACAAGACCCTGAA
+ACTCGTTATCCGATCAAAATCGGCTAACAGATAACGGACTTGCATACTTT
+TTATACGGGAAACGTGTAGAATTTTAAAAAGTTTTGTGCCATGAAAATGT
+TGCTCACCAGTTTCAATTTTGTTCTGATGCACTTTTTCCAGAATTACTAC
+ATCAGCACGTATTGATAACTTGATTTAATGAAGTTACCCGAAAAAGTATC
+CACACCCCATAATCAGCATATTTCATATGTCAAATATCAAATTTCCTGAA
+TTCCGCACACCTCTGCTCTCCATACTCCAACTAATTTTAATTGCAGAAGA
+CGAAATAGTAGTCCGCTGCCTTGCCGAATGCGTCGACTCCATTGGACTCA
+ACGTGATTGCTCGTTACGAACGCCTGAACATTGAGACTCATTCGGAATTC
+GGTGTGAAATGGTTCTTCAAATTATCCCGTCTCTTTCTGAAACATGGATT
+TACTACGCATTCCTTCGCGATTGCGAATATATTATTTGACCGACTTTCGG
+CGAGAAAACGAAATACAATGATGATAGATCGTACGAGTTTAGACCGAATT
+GACAGATCACAGGAACTTATCAATCTTTTGGTGGAGATCTATGTGGCCGA
+GGGTAACTCGGTAGCGTTGTCCTCTCTGCCACCTGCGGTACAAAATAGAC
+CGGATGTTCGGCAGGTTATGAATAAGAGTTCAAAGGAATGGTTGAAATTG
+CTGTCTTCGAATCAAATGGACTCGTGGGAGTTGACTATTGTGCAGTGGAT
+GTGGTAATTGTTTATTTTGAAATTTTTCATTAGAATAGAAAGCAGTTTTC
+TGGAAATTTTCAGGAAAACGCATTAATTTTTTACCTATTCTGCATTTCTA
+GGTTCTTCAATTTTTTGAGAAAATATATATTCCTTCGAAAAAATCACTAA
+CTTCTTTTCGGAAATTTAAAAAAGTTACAGTCGACGACTTTAAAAAATTC
+AGTTAATAAAATTAGATTTCAAAAACAAATCGAATTTTTTAATTTGTACC
+GAAATCTGGAAAATATTTTTAAATGACTCCAAATTTTTCCCTGATTCCAA
+ATATCTATGAGATAAAATTCAAAAAATAATCCCTTTTTGATCTTGAAATC
+GCCGAATTTCATTTGTGCACTCATGAGATTTCGAAGTTTCGCGCCAGAGA
+CCCCATGTGTTGATTTACGAGATTTGTGTATATTTACGAACCCCTTAACC
+TTTATCGGTTGCTGATTTCCGTTTTTCAACGAGTTTTCTTCAGTTTCGTC
+GGTTTTTGTTAAAGTTTTTGTTTAAAACATTTTCAAAAAAACTTTGACAA
+AAATGAAGGGAACTCGTTGAAAAACGGCAATCAGCATCCGATAAAGGTTA
+AGGGGTTCGTAAATATACACAAATCTCGTAAATCGACACATGGAGTCTCT
+GGCGCCAAAATTCGAAATCTCATGAGTGCACAAATGAAATTCGCGATTTT
+AAGCTGAAATAAAGAACCAGGGAAAAACATTTTTTCACATAGATGTTCGG
+AATCAGGGTCAAATTTAGAGTGAAAAACTTTTAAATTTTTAAATTTTTTC
+AGTGGCATCCAATTCAATGCAATCACCGGCGATAAATACCTGAATTCAAT
+TCTTCGTTGCAATTTCAACGAGTACACCAAAAAAATCGATTCCCCATTAA
+AATTCGTCTATTTTCAACTATTCCATCTTTCGACGAGCACTCTGGAAATC
+GAAGAAGCCATTTCTAGCATGCCGTTGGCTCCAACAATCGATCAAATGCG
+GCTTATGATTATAGCCAACGCGACGGCAAGCTTCGAGCCACAATCCGTTG
+AAGAGCACGTTGTTCGAGCTGTTCGAGAGCTCCGAGAGACGTCAAATCGG
+CGAAAATCCGGTGGAAATGTGAAGGGAATTAATGAAAAAACAACGAGAAT
+GGTGAAACTGGCCGAGATGCTCACCGAGAATAAAGCATACGATGTACGGA
+GCAAAAAATAATGGAAAATTTGAATTTATTCAATTGTCAAAAAAAAGGAA
+ATTTCCTTAATTTTTCGGTTTTTTTTTTCGGAAAAATCTGAATTTTTTCT
+ATTTTGAGCAAAAAATTTAATTGAAAATCCGGAGAAAATCGTATACTTTT
+TCTGCGAACCATTTTGTGGGCGGAGCCTAACTAGTAACACTTTTCAATTT
+CCAAACAGAAAAGTGAGAAAAAATTCCTCTTTTTCTCAAAAATCTAAAAG
+AAAAAAAAATCGGAAATTTTTGAATTTTTCGGTTTTTTCTGAATTTTTCA
+ATTTTCATTCAAAGAAGGTCGAAAACTTTTCGATTTTCCGGTTTCCTTTT
+TGAAAAAAAATATTTTAAAAATGTGTAGTTTGTAGTTTGTAGTTTTTGTA
+GTTAATGTCTTCCACATTTTTAGGCGGCAATAAACCTGCTCGACACGTGG
+GAGCACGAGTGTCTCCAATGGACATCTGTCGCTGCCGAATCAATCGATAT
+CGATTTAATTCGAATCTGCAAACAACACGTGACGTGTCGGTCGGGAGATC
+CAAGAATGGCGGACATAAATCTACGAACAATGCATCCACGTGTCCCGGTG
+ATGAGTGACCTGGCGATTGCCGAATGGTCACTCGCGTTGAGCAAGATTAC
+AATTGAATATCGGAATGATATGGAAGAGGGTATTCGGATTTTGGAATTTG
+GATGCAAACATTTACAGAATAAGGATTCTGTAGAGACGAGGTTAAAGGTA
+CATGCGGTCGGGTCTTGCAGCGAAATAATGCATTTTTAAAAATTCGAGAA
+AAAAATTGTGAATTTTGCGCGTAAAACGTGATTCAATCTCGAATTGTTCT
+ATAGATTTTTCCGACAATTCGGAAAAATGCCGGAATTGAAAATTTCCGGC
+AAATCAGCAATTTGCCGTAATTCAAAATTTCCGGTAAATCGGCACATAGC
+CAAAAATTAAAAATTTCGGCAAGTCGGCAAATTGCCGGAATTCAAAATTT
+CCGGCAAATCGCCAAATTGTCGAAATTCAAAATTTCCCGAAAATCGGCTA
+ATTGCCGGAAGTGAAAGTTTTATTGATAGAGATAAATTTAGAACTATCAC
+TAGAATTTAAATGTAAAACAACTAGGAGTTATCATGTAAAACTTGTCATT
+TGAATTTAACACTAGGAGTCCAATAGATTTTCAGATTTTAAAAAATTAAT
+ATAAATTCAGGAAATTTTTTTTGAATTTATCCACATTAATATTCGGTATC
+AGGAGCATAAATAGGATCTATTGAGATATTTTAACAAATTTCCGAACAAA
+GTTTCAAATATTTTTTTCCAATTGATAGAATGTTCCATGAAACATTACAA
+AAAAATTATTCATCAGGTTCTCCTAAAACTCCATTCCGTCTGTATTGGCC
+AACTGTCGAAACTCGAAGAATATCGCGAAACGCGTACCTACCGTATGAAG
+CAGCAGGCGGTCACCGCATTCGAACAACAAATTCAAAATTCGTGTCGAAC
+CAGTCTGGCACGTGGCAATTCGGGTGACGAATGGACGAAAAAAACGGTGC
+AACGGGTGAGAAAAGAGCATCAGTTTGAGAAGAATGATTTGGAAAAAGTG
+GATAATTCGTTGAATTCGGCGGCCCGGAAAGCTGTATCGTCGGGTTTTGA
+TGCACTTTGTGAGCAATTTTTGAAGTTTTTATTGAAAATTCAAAACTTGC
+ACAAAAGGATTTTAAATTCGATTTTTCGCGATGTTTTAGCAATAAAATTT
+TGAAAAATGACAAATTTTTGAAATAATTTCAGAAAGAGTGTAAAGTTTCA
+GAAAAAAAAATTAAAATTAAAATTTATTTTAAAACTTAAAAAAACCGACT
+TTTAGCGAATTTTTTTACGAAAAACAAAGTATTTAATTTCATAAATTAAT
+TCAAAAAAAATATCTAAAATTTTTGTGAAAAACTGTTTTATACAGTTTCA
+GAAAAATTTAAGAAAAAATTTTTTTTCAGAAAAAACCGGATTTTCTGTTA
+ATTTGAAATTATGGAAAAAAAAACCCCAAAGGGTATTACGGAACTACAAA
+ATTCTGAGAATGCGTACCGCGCAAAATTTCTCGTGGCGAAAACTACAGTA
+ATTCTTTAAATGACTACTGTAGTGTTGGTGTCGATTTACGGGCTCGATTT
+TAAAATTGAGCAAAAAATTATCACATAATACGAAGAAACGAAGGAAAATG
+AAACTAAGTTATAAAAAAATTCGAAAATCGAGATCCCGTAAATCGACACG
+AGCGCTACAGTAGTCAAAAATTAAATTAAAATTAAAGGATTACTGTAGTT
+TTCGCTACGAAATATTTTGCGCGTCAAATGTGTTGCGCAATACGCAGAGA
+TCTCAAAATTCTATGCTCCCGTAATAGATTTAGAAAAATTTTCCGAAAAT
+TTACGTCTCGAAAAAGAAAAAAAAACTGGTGTAAAAAATTACACCAGTTT
+TAATATTTACTGAAAAAAATTGGTAAAATCTAAAAATTAATCAGCTGAAA
+TTGATATGTTTTGGGATAAAAAATTTTGGCGGGAAACTCAAGTTAAAAAA
+AAAAATTTCAGTATGCATCAGCCAACTGGAAGACGACGACGAAGCGATCC
+GCGCTTCATCTCTCATAATATTTCCATTAATCGATGTGATCTACAAATAC
+GAAACGGACGTCGGAGTGATCGCCTTGCTCAAAGAGCACACCAAATCGAA
+GCTCCCGTCGAAGCTGTGGATAAGTGCCACCTCACACATTGCCTCTAAGT
+GCTTCTCCATCGAAAAATCGCAAATCACGAGACACTTATCACAGATTCTG
+TGTCATCTCATCTATGACTACCCGTATCACGTTTTGCACACAATTTTGAT
+GTATGATGACGAGAAGAACGCTTCCAAGGTGAAAGGCTTCTTGAAAACGA
+TATTTGACGCGCGAGCTGACCAACGGGATTCGTCGAAGCTTAAGGAGATT
+GTGATTACTATTCGTGAGGCTCACCAGGCTTATAGGTACATACGGCGGCT
+AAATTTTTTTTGAAATTTCGAAAAAGACGAGAAATTCGATTTCTTATCAA
+GTTTACAAAAATCTTCGCTTTTTTCTGACAATTTTAGTGTCGTGGTATCC
+AATCAACGAAAAAAATTAGGTTCTTCTGGTTATTTTTGAGCATATTCAAT
+AATTTAAGCAAATACTCTTTTACTTCTAAACTTTCATCGGCGATACGTGA
+ACAATTTCCAAAATTATATATTATCTAACGCTACAGCATATAATTTTTAC
+CAATTTTCATTCATTTTGATGGAAAAAAGCATCTAGAACATGTAATATGT
+TCAATTGTTCGATTTCAATAAAAACCGACGGCATCCTTGGTTTGAATCGA
+AAGTTTAGAACAGTTTTTTTCAGAGAAATTGCAATGCTTGACGTGAGAGG
+AAACGTTCGGATACAACGTGTTGAAATAAACGGAAAAACGATGTACCGAT
+GGCCACATGATTTGAAGATTTTCAAGTGCAAATTGCGTCAATTGCCGATT
+CCCACCATTTCGCAAAAGGTTTGTTTTTATTTTATTAAAATAATTTAATG
+AATATGTATTTGATCATACAAAAAAAAAATGTTTTCTTCTAAATTCCAGA
+TTGGTTGCCCGGGTGACTACTCGACGACTGACCTAATCACGTGGAAACGA
+TGGAAAGATGTATTCACAATTGCCGACGGAATTTCCACTCCAAAAATCTG
+GGAAATTGAGGGTAGCGATGGAAAATGGTATAAAACTGTGTGGAAGAAGG
+ACGACGTACGACAGGATGTGCTTGTTGAGCAAATGTTTGATGTTACGAAT
+AATATGTTGGAGAAGGCGATGCTTCGGACGTATAATGTTGTCCCGTTAGA
+CACTGAATGTGGAGTTATAGAGTTTTGTGGTGGAACTGTTAGCTTAAGTT
+CGTTTTTTTTTCGTTTTTGAAAAAAACCAAAATAGTATTACGATAACACA
+ATATGCTGAGAATGCGTATTGTACAACATATTTGACGAGCAAAATATCTC
+ATAGCGAAAACTACAGTAATTTTTTAAATTACTACCGTAGCGCTTGTGTC
+GATTTACGGGCTCGATTGTCGAATATTACGGGGCCATGAGATCATGAGTA
+TGCCTATTTACTGGCGCGAAAATATTGGCAGGCCGCGGCAGCGAGAGAGC
+GTGTGGCGAAGAGAGACGCAGGTCCCTTCGCTACGAGATATTTCCCGCCA
+GAAAAGTAGCATTCTCATGATCTCATGGTCCCGTAATAGTGACAGCGATA
+TTCCATTTATTTCACTTCAAAAATCGAGATGCCGTAAATCAACACAAGCG
+CTACTGTCATTTAAAGAATTACTTTAGTTTTCGCTACGAGATATTTTTCC
+CGTCAAATATGTTGTGCAATACGCATTCTCAGAAGAAAAAAGAGGGGGGC
+AGATAGCTCAGTCGGTAGTGGTGGCCGCTAGCAGTCTGGAGGTCACGAGT
+TCAAGTCCGGCCTCACCCCCTAGGTTCACCCAGCCTCTATTGGGAAGTGG
+AGCAATCCACGACTGGATTATCGGCCACAGTCCCCGGCTAGGACGTGGCT
+TAAATTACAGCCCAGAGGGATCACCACCAGGCAGTGTACCTGAATCCCAG
+ATCCGCAGTGCATAGCACTTGAAGAACGGATCGTCCTTTAATCCTTTAAT
+CCTTTAAAAATGTAAAAAAATTTCATTGCAAAAATATCAAACTATGAGAT
+TTTTTCTATTATTTTTCAGAAGAAGTTATGTGTGGTGTGACACGAGAAGG
+CGGTCTCCACCGGGAGTTCAATTCAGAAGAAGTTTCGGCGAGTAAAGTGT
+CGTCAATGATGAGACAAGTACAGACAGAGTCCACAGAGACACGACGACAA
+GTTTTTGTGGAGATTTGTCAGCAGTATTCTCCAGTTTTTAGGTAATTTTT
+CTGAAAGTTGTCGAAGTTTTTTTTTTTGAAATTCAAAAAAATTCCCAAAC
+AATTGGCCTTTTTTCAAATTTTTCCAAAAAATAAAATTACAGACACTTCT
+TCTACACCAACTTTTCGACGGCGCAGATTTGGCGGCAAAAAATCATAAAT
+TACAGGCAGAGCTTGGCCACGTGGAGTATTGGTAGGTTTCGAACTAAAAA
+TGCTAAAAAATTTTCGAAGAATTCGAACATCTCAGATTTTTTCCGAAAAA
+TAATAAAAACGTTATTTTCCAATTTTCTGAAAATAAGAATTTATTAGTTT
+CTTGCGAAATGAAGAGTCTCAAAAAATCATATTTTTTTTAAAAATCAGAT
+TTTTAAATTCTTTTTTTAAAAGTTTTATCGTGAAATTGAACGTTTATGAA
+AAATGGCGAGAAAAACTTTTTTTTCGCTTTTTCAAATAATTCTCAAAATA
+AAAATTCCAGTGTGCTACATCGTTGGCCTCGGCGATCGACACGCGTCGAA
+TATTCTATTCGATCAGAAATTGTGCACATTTGTGCATATCGATTTGGGAA
+TGATTTTGGAGTATAGTAAACGAACGTTGCCAGTTCCCGAACAAGTTCCA
+TTCCGTATAACTCGAGATGTGCTCGACCCGATTCTGATTGAAGGAATCGA
+GAATGGACAGTTGGCTGAGGAATGTACGCAGATTATGGAGAAATTGAAGG
+AAAATGGAAAGGTACGGCGGTCTGGGGAAATTTATACGAAAAGAAAATTT
+TGGACTGACAAAATTTTGGACTTGTAAAGCTATTTAAAAAATTCAAATTT
+CCCGCCAAAAATATTTTTTCAAAGAATTTGAATTTTAGCTAAATTTTTAA
+ACAAAATCTGAAGTTACCGCCAAAAGTTTTCCAAAAAAAATCGAATTTCC
+CGCCTAAAATGTTTTTCAATAAATTCAAATTCCCGCCAATTTTTTTTACA
+CAAAATTTGAATTTCGCGTCAAAAATTTTCCAAAAAATATTCAAAATTCC
+CTGAATAGTTCAATTTCCCACCAAATATCAATTTTTCTGAATAAAATTTT
+AGAATTTCTCGCCAAATTTCTTTTTCAATTTTTTCAATTTCCAAAATTTC
+CAGGTAATCCTCGGTGTCGCCTCTGCTCTACTCCGCGAAACGATGACAAA
+TTTCCGAGAAGCCGAACAGGCTGCCGGCCGCCCGTCCTACATTTCTGAAA
+TGGCCATCGGACGGCTTCGAGAAAAGCTACGGGGCACCGATGACGGTGTG
+ACGGCCCAATCGTCGAATCTTCAAATTCGGCGACTTTTACGAGAAGCTAC
+GAGTGCTGACAATTTATCGCGAATGTTCTGCGGATGGATGCCGTTTTTGT
+AGAGAAATCAGAGAAAATTTTTCTCGAAAATTAAAATTTTTACTGTATTA
+TTGTTTTCTCGTATCAATTTTTCAGAATTTGCTTTGTTATTTTATTTTAC
+GCGCAAAATAATCTTTCTAATTTAGAAATTTTAAAATTATGGAAACTTTC
+TGAAATTTCTGCAAAATTCTAGAAAATCAAAAAATTTAGTTTTCCATCCT
+AATTTTTTTTTTCGTTGATTTTCCCCAGAAAATTCAAACTTTTACTGTAT
+TATTATTTTTTCATATCATGTAATGTTTTTTGTTCAACATTTACATGTTT
+TTCCTACCTCTTCTATGATTTCCCCTTCCCCCAGGTCTCATTTTTCTTCA
+CAATTTTTAAAATTGATTCACTGTTGAATGTGTTGTCTTTTTTCTATGCG
+AATTTTATTAATTTTATGAAAAAAATTTGTAATATTTTTGTGTAAATTTT
+GAGTCTTCTTACACTACAAAGTTAACCATTTCAGAGGAGTTTCAAAATAA
+ATAGTGAATTTTTACAAAAATTAGATTTTCTGATTTCAGCGTACATGAAT
+TGCCCGTTTTCAACAAAATAAGACAACTTTTTATTTTTGCCCAATTTTTT
+TTCAGCCATCTAATGACTGTCCTTTTTTTTTGGGCAAAAATAATAAATTT
+TCTAAAAGCGTTTAAAACTATTATATTTTGAAAAAAGACCATTTTTTAGG
+GCTTGGCAATTTTAAGTTCTCTAGCTACAAATTGAACCAATTTAGAGGTT
+TCAAAATTGTGAGTTTTTGCAAAAATTGCCAAATTTTGCCACTTTTTAAT
+GGTTTTTGATGGGTTAAACCTAGATTTTCTGAATTCTGCATATATGAATT
+ACCCGTTTTTAACAAAATTAGACAACTTTTTATTTTTGCCCAATTTTTTT
+TCAATGACTGTCCTTTTTTTTTGGGCAAGAAAAATAATTTTTTGGAATTT
+TTTTCTGAAAATGTTCGAAATTTTTGAAGTTTCTCTTGAAGCACTCCGAA
+AAACCAAACGACCAGCACTACTTGCAAAGTCCGAAAATTTAAGTTTAGAA
+AAATTTTGAAGTTTTAAAAGCTCCCAAACCAGAAACTCACGATATAGAAA
+TTATTTCCAAACATTTCCGAAAATTCCAAAAAATGAAAAATCAGAACAAT
+TTCGAAATTTTTTTCAAAACACTTCTGAAAAAAACCGAAACTGCAAAAAT
+TTGAAAATGTGCTAAACTCCAAACTGTACGATTTTCCACATTTCAGAAAT
+TCCAAAATTCGTAAATCTGCCAAATCCCTTCGGCGCAATAATCCCCCGGG
+GTACCCCCCCCCCCCGCCCTAAAACCTTTTGCCTCTATTGTCTCTGGCGC
+AGAAAATTGAAATTAAAAAATGAATCGATATTTTAAACTGTTATTCGTAG
+CCATCTTCTCCGGATGTATAATCGCCTACACGAATCTATTCAATCGATCG
+TTTTTCAACGGGTACTGTAGTAATAATGCTACGTGGCAACAGTCACAAGG
+CGAAAGCGACAGTCACGTGGCAAATTCGTTGGATTTGTGTCGTGGCGATG
+GTGTGAAGCAGTGTATTCCGCCGTTGATGAGGTTCAAACAGTTGTATCGG
+GTGAGAAAGATTATCGATTTTTAACACCCGTCTCGCCAATTTTTTTCTCA
+GAAATTGGAATTCCCGTCACAAAACTTTTACAGAATGTGAATTTTCGAAG
+AAATTGGAATGACACCCAAAAATTTTCTCAGAAATCTAAATTCTCGGCAA
+AAGTTTTCTCAGAAATTTGAATTCTCGTCAAAAATTTTCTCAGAAATTTG
+AATTCCCGCCAAAATTTAAATCAGAAATTTGAGTTACCACCCTTCTCTTC
+AAGTAACAGTATTCAACAATATACAATTAAATAGCTTTTCAAATTCCTAA
+AAAGTTTGCTGGAGTTATCAATTTTTGATTCAAAACTCGCTAAACCACTT
+GCCCATGTAGAATACATAATCAATTCTGAATAGAACGCTATTTTATCCTA
+TTTTCAGACATCAAAACCGAATAGCCTAATCGCATGTGTCATTGAAAAAT
+CATTTTCGACATTTCTTACTGCTATTATGTGCTTTTTACACGATCCACAA
+ACATTTAAAGACAGCAATCGAACACTGGATTCTGATATTTTTGGAGACAG
+GTTTGCGGCAAACGAACTCCGCTGCCGACTCTCGAATTATCAATTTTGCA
+GGCTTTGTAAGGATAAAAACGAATTTACCGAGTTGAAGAAGATCGGAAGC
+TGGCAGAAAATGTCGATTTTCACTGTGGTTCGGAATCCGATCGATCGGTT
+TGTATCAGGCTTCACGGATAAATGTTTAAGAGAAAATGTCTGGAAAAAGT
+TCAAAAATCGATGCGCCGGATGTAAGACTGTGCGTTTTATTTGCTAAAAT
+CTTTTACTTAAACAATTTTTTTGGAATCTTTTATTTTCGGGAGTTTCGAA
+AGTATATTGGAGTTTTTTAGAGAAAAAAATATCAATTGAAAAAGGTTTTT
+TGAAAGGGGGTAACATTTTTCTAGGCCACTAGGCTTTGTAAGGTGGCCTA
+GAAAATAATGTAAAAATCTAGGCCATAAGGGTTTATTGCGTGATGGCCTA
+TGAAAAAGCTAGGTCGCCATAACTTTTATCAGGGTTTAGGAAAGTTAAAA
+CTTCGGGCAGCAAGTTTCGCATAATGACCTAAAACTTTCTGGAGAACTAG
+GCTATAAAAATGTTCATGATGGTTTCAAAAAGCGGAACATTCGGTGACCA
+TAATCTTCTAGAATTTTTAGGAAAACTAGGCCATTAAGGTTTCTTCCGTG
+GTCTAGAAATTCTGGAATACTAGGCTGCCAGGGTTTCTAGGCCACATAAG
+AAAGGCCTAGATACAAAAATTTCAGAACGGTCTAGAAAAGTGGATAACTA
+GGCCACCAATTTTCTCTTCGGAGTTTCAAAAATATATGATTCATGATTTA
+CTTTTTTAAGAGTTTTTTTTTTCAAAAATTCTAAACTTTTGACACTAAAA
+TGCTTCTGAATTTTTGAAAACTTTGAAAATTAAATGTTTAAAAATAATTT
+TTTGAAAATCTCTCAATTTTTTTTCTTCGAAAAGCTCAAAAAAACGATAA
+ATTTCCACATTTTGGCCAGAATTTAACATGTTTCGTCGATAAAATGTACG
+ATCGGATGCATAGATTCGCGCGGAATCCGTATAAAGGAATCGATTTCGAC
+GACAGTCACTTTTTCCCACAATCTTGGTATCGGTAAACGCGCTCTATAGA
+TAAAGTCTCAATGGAGCGCATTTGCATTTTGAAATTTGATATATTTGTCG
+TTTCAGGAGATGCGAGTTCTCGTCTCATCTTGTCAAATACCAAATTTTTC
+AATTAGACGGTGCAAATTTCACAAATCAACTTCTTGGACTGCTGTCCGAG
+CGGGGAGTTGATGAGAATGGAATTAACTTTATTAGTGAGTCTTAATCAAG
+TTTGGGTCTCACCGCGAAAACCGTAATTGATTGGGGACAATGGGACCCAA
+GAGAGCCCAATGGAGCGGAATTGCAACTCCTATGAATTTTCCAGACGGAA
+GTCTCCATCACCGGACCCCACACAGCACAATGGATTCCGTGGAACGGGCG
+GCCGTCGAGGAAACTGTTCTGAGCAGTCCGTATTTGTTGCGAAAAATAAT
+TCAAATGTATTATTTTGACTTTTTGCTATTCGGGTATAAGCTTCCTGATA
+TTCCAGTTGGAAATTAGGAAAGTTCTTTATATGTATTTAATTGTTGTTAA
+ATAGTAAAAATCGATAAATTGCTTGAATTTTGATAAATTACGGCCACGTC
+AATTTTTAGATAATTAACGGGCAAAAAAAATCTAAAATTCTTACAAATTG
+AAAAAAAAAATTTCACAAAAAATAATAACATTTAGTCTAAATGTGTTATA
+GCTTAGGCTGAGGTTTAGGCTTGGGCAGGTTATTTTTTAATTTTCAAGGT
+TTCTCATTACATACTTTATTTCCGAAATACAAAAAAGAAGTCTCACAACG
+AGTCATCAGTGCGTGTTGGTGGGTGGGGTGGGAGATTCTGGTGGCGACCT
+ACAACTCACAAACAAAGATGACAACAGGGAAAATGTACACGTGGCAATAT
+GGTGAAGCTATATGTATATATAATGAATAATGATATGTAAATTTGCATAA
+TACAGGAACAGTACGTGATTGCTGGGGCGAGTAGAAATGTGGGTTATTAT
+CTATCGATTACCATTACACATGAATTACGCTGGATTACGGTTAGAATTTT
+GTGAAAAAAAATGAGTAAAACGCTGGGGCTATAAATCTATAATTGTCGAA
+GATGCTCAACGAGCCAGGAACGAGGGGAACATTGCGTCAAACTGGGCGGT
+CAATTCCATTAATGATGGTGCAGCTTGTGCATTGATTGCTGCAGCAGTAG
+GGACTCCATGCCTCATCACCGAATCGATAATCTTCTTTCCAGATGAGAAA
+CGCTCGAGACGGGAGGCGTGTTGGAGCACACGCTGCTTCATTTTCTCGTA
+CCATCCAGAGTAGAGAAGCAGAATAGCTGGTGGAAGTTGACGTTCTCTGG
+AAAAAAACAAGATTTTCTCTAGTTGCCTTAACACTTGGATTTACAGAATT
+AGTGAATATTTAAATCAGGGTGGGCGGCAATTTTTTTTCCGGCAAATTCA
+GCAAATTGCCGATTTGCCGGAAGTTTTTAAAAGGATTTTTAAAAGACGGA
+AACACTTAAAACTGTGCCTTTTTGAAATTTTCTCCCGATTTCTTTACATA
+TTTTCATAGATTTTACTGACTTTTCAAAATAAATGTAGGAACATTTATAG
+GATGCGTACAATTTTGCCGATTAAAATTGAAACTGTGAAATTTTCAGAAA
+AAATGTGCCGAATCACAATTTGCCGAAAATTTTAGTTCCGACAATTTGCC
+GTTTGCCGGAAAAAACCGTTTTCCAAGCCACGTGGATCATTTTTTGAAGA
+AAAAAATACGGCAAATTTACAGAAACTTTAGTACCATGTGGATTTTTTAA
+GAACTATTGCCAAAGTACGTGGAATGTTCAGAAATTTTTTTGCCTTTGTG
+AAATTTTGGATTTTTCTGGATTTTCGGAAAAAAATTCAAATTTTTCTATG
+AAGACGAATTTCTGATTTTTTTAAAAATTTTTCACGAACTCAAATAATAC
+TCAGACGCGAAATTTTACGTTTTCCGATCAAAACACGGTACCCGGGGTCT
+CGAATCGACATGCAGTATTTTTCTCGCTTTGTCATAGTTTCTCGATAAAA
+ATGGATTTTTTTGAATTCAAAATCCTTAAGTTTCTACCCAGGGGAGAAAA
+AGAAGACTATAAAAATTTGAAGTTAAAGTACTCTTTAAAGGCGCCCTTTT
+TTCGAACTTAACCAAAAATTGTCGTGTCGAGGCCTGGTACCGTATTGTGG
+TGCGAAAATCATTTAAAAAATTGCGTCGATTTTTGGTTTTTTGTTATTTT
+AAAAAATGTTCAATTTTTCAAAAATAGCTTTTAGATAAAAATAATAGGTT
+TTTCCTTCTTTTTTTCCGGCTAAATAATTTTAAGAATCCATTTGCCACGT
+TTCATCACAGAAAAAAAACTAACTCTGTGCCAATCAAAGCGGCGGTGCAA
+ATCGAAATCATTTGCTGAACGACATAGTTGCCATACTGGTGGAACAGAAG
+AATATCCAACGCATCACGATTCGACTCGACATCCTTCACATATCCACTGA
+AAATCTCCTCCATCATCTCGTGAAGCAACGCGGGCGGTGCAAACAAGAAC
+GCTCCCTCGATGACGTGCGACGCATACTTGTCCTGTGACATTGAGAGCAA
+GTTACGGAGCAGGCATTTATCGATGATAGTGTCTCTGTACATTTCCATGA
+TACCCGACGATTTGATGACGTATTGGATGACGTAGTTGGCGAACTCGTTG
+GAAGACAGCCGGTAGCAATTACGGACGATACACGTCATCAGAGAATGCAA
+CAATTGAATACGGAATTTGAAACACGGGAGCTTGGGATTCTCGGCGAGTC
+TATCGATGACCTGTTGCACGAGACGACATCCATACTTGTCCTGGCACACG
+GCCATCAGTGAATCTCCTGACGAGAGGAAATGCACGAAAAAGGTCCACAT
+GTCGACTGGAAGTTGCTTGACGACACGTTGAATCACGTGGATCGAGATTT
+GATCATCCAAGAGCTCAGCACATTGCCGCCAGGTCGAATGTGCTGAGCTC
+TTGGATGAGCTGGAAGACGTTGGAATGGTCGAATTTCTGAAATTAACAAA
+TTATTGATTTATTACACCTGGAAAGGCCTAAAAAGACCAAAAATAGCCCT
+AAAAATTTCGAAGAAATGGATTAATTTTTAGCTAAAACGTAATTTTTTGC
+CAACTTTTCTGTGTCGCGATTTTTTTAAACCAAAATCGAAAAATTTCGTT
+TTTCGATATTTTGAACAAATTTCAATTTTTTCGGGAGAATATCTTAAAAC
+TTAATTATTTTCCTCTAGGAGCCATTTTGTATGTTTTTTTCATCGACAAA
+AAATTTTCGTTAATGTGTGCACCTTTAAGTAGTACTGTAACTTTAAACTT
+TCATTGCTGCGGAATTTTTTAAAATTGATTTTCAATGTTTTTCTACAGTT
+GTCGTCCAATTTCATGCAATTTAGAAAAAAACAGAAGGAAAAAGTGAAAC
+ATCGATTTTAAAAAAATTCCGGAGCAATGAAAGTTCGGAGTTACAGTACT
+CTTTGAAGGCGCACACCTTTTTTGTTTTAACAAAAATTTGTCGTGATGAG
+ACTGGGGACAGTTTTTCGGCGGAAAAATCGCAAAATTTCGGCTAATATCG
+AAGAAAAATCAATTTCCGACCGCTGCGACACTTTAGCAAAAAATTGTGAT
+TTTAGCCAAAATTCAGTTATTTTTCGGAATTCCCGTGGCGAGACGTATTT
+CTCCCACCTGCAGAGCCAACTGCACAACTCGACATGCGAATTTATCCTTG
+CACATGGCCAAAAGCCCTCCGTCGATCATTTGACGAAGCAATTCCCGCTG
+CTCGGCCGGTGTTGCGAGCTCGACGAGCTTCTGAACGATGAAATTGCCAC
+TTCGACTGTGGCAGAGCCCCACGAAGAGCGTCGTGGATTCGGTGAGCTTC
+TCGAAGACGGCTTTACGAATCTGATCTTCGGAATCCAGTGGGTAGTTGGC
+CTCCAAGAACTTTACGCCCGATGGATCGATTGCGAAATCGATGAGCTGCC
+CGTTGAACAGCACATCTTCGAGCGAAATGAAAATCGGAGCAACTGGTGGT
+GGGGTCTCATCGTCGGAAGATCCCGATCCACTGTTGAAGATGTAGCTGTC
+CGAGTCGGAGGAGGTGGTGTTGCTTCCGTGGCGGTAGGGAAGAAGCTTGA
+CCGGCGGCTTTGGATTCTGGAAATTCGAATTTTAAATTTTTATTATATTT
+TCTATTTAAATTAGAAGTTTTTATGCAATATTCTACCTTGTTCTTGTGAG
+TTTTGTTCGACAAAAGCGAGAAATCCGGGTCGAAATCGAACGACGCGCCG
+AGCATGTTGTACGAGTCTGTGCTTCTACGATTCGGGGTCATTTAGACAGA
+AATGAATGAATACAGGTTAGTAGACGCTGAAAAATTTTGGGAATTAGGAT
+TTTCAACGGAAAAAAGAGTGAAAATGAGAGGAAAACATGTAAATTTCAAC
+GAAAATCGCGAAATTACCGCGCATCAAAATTCAAAATTGAATTTTTCGCG
+GTGGCCCGGGTTACGGTGATTTTTAAAGGCGCATGGTTGTTTTGAGTAAG
+GTCTTGACGCGAAATTTAAAATTATTGAACATTTTTATTTTATTTTTACA
+TTTTTAAAGAAAAAAATGATTAAAATTCGATTTTTTAGGAGAAATTAAAC
+ATTTTCACAAAAATTGCAAGAAATCGCTCGCCAAAATTCGAAAATGAAGA
+GTTTGGCGGTGCTCATGGATTACGGTGGATTTAAAGGCACATGGCTTTTT
+TGTATTAGGTTTCACCACGAAACTTGGAGTTTTGATAGTTTGCTTCCCAT
+TTTGGGATTTATTTTTTTAATTTTCGCTCGATTTTCACACATTTTCACTC
+ATTTGCACTCAATTTTTTTGCAGAAAAATGTCAATGGATATTGTTATGAA
+GTCAGATGAGCAGCCGTTCATCTCTGCGCCTGTATGCTTTAAGTAAGCTC
+CAATTTTTGTTATTCTGGCCTAAAATTATTTTTTTGATTTCCAGAACGTT
+CGCATTTTTCGCCAAAGCATCCGCAGAGGAATGCAAACTTCTCTTCGGGC
+TCCAACGCTCGAGAAAGTTTCCAGCAGGCCACGGGGCTCTCGGAGAAGAT
+CACGGAAGACATTTACCGCCAAATTGAGTAGGTTTTTCGATTTTTTTACC
+CTTAAAAACTACTATTTTTCTATTTTCCAGCGTCTCCCACATTTCGTCGA
+TGGTCTTCAACAGAGAAATGGACGGTGGCATCGAGAGAAATCGGCTCGGC
+TCGCAAGCGATTCTGCTCGACGAGAACTCCAGGCGCCGCAATCCACAGTT
+CAAATCGATCGCGCTCCGCTCTCCGCTACGATCACATCGATCATAGAGCG
+TTGGCAAGGAAATCGCCTCATCTGATGCCTCCGACTTTTATCAAAGAGGA
+AATTATGGATGATGAGCTCGACGAGGTGAAGGAAGAAGTGGTTTCCGTTG
+GAGAAGCCGCCTTGCCCACGCCAAAAGTCGAACTGAACATGGACCATCCG
+GAAAAGGACCTGATCATCAGCATTTCCGTGTATCTCGGCTACACCCGTAC
+CCTTCAATACCACGAGATTCGCCTCGGACGTTTGATGAAGATCACGGATC
+GGCTCGAGCTCACCGGAGATCACACGCTTCGCGATCTGAAAAACGCGTTC
+TCGTGCCCCATCGATTTCTCGTTTTCCGACGATTTTAGCGAGAAAAAGCC
+GTCGTTCAAGGATATGGCGAAAAATAAGTGGCCGTCGACGATGTTCTTCA
+TTCATGACACGTTTTATATATAACTGGAAATAATTTAATATTTTTCGAAC
+AAATTTGAAAACTATAAAACCATCTTATTTTGATAAAACTCCGCCGCTGC
+TCTCTGAAGCAATGAACTGCAATCAGACATCGAAGGGATCAGCCGATCAC
+GGAACCAACCTGCCATTGAGCTTCTGAAAATTAATATATTTGATTCAATT
+TATTGTACGAAATCGTTTTTACCCATATCTGTGAGCTAGCAAGCTAGCTA
+ATCGTGATTAATTGTTGGGTATTCCTTCGCGTTCTTCAGCTTCTCCACAA
+GCAAAATTCTTGTCTGCTCATCACAAATGATGTCATCAGCATCGCTCTGA
+TCTTGAAAATCCTGAAATTATAACATTCTAGAGGGTTTCTGATGAGAATA
+GTTACCTTACAACCAACACCAAATACGTTCTTCATTATGGCATCCGGCAG
+CTTTCCATAATCGCAGAAGAAGTGCTCGGCATCACGATCGGATGCTCTAT
+TTGGGAAACGACCGATGTAGACACGAACCATGTTGAGTGGCCGAGAGAGG
+GATCATCTGAAACATTTAAATGTTAACTAAACAGGAGTTTAGAAACTTTA
+AAACAACCTAACCTCCGTGATAACGTAGTTAGCTTCTCGAGTGAGCTTCT
+TCTTCAAAATAAAACAGAATGAAACAAGAATCAAGTGGGTAAAATTGTAA
+AATGAAGTATTTCAGACATTTTCGCTAATTTTGGCAGTAAAAACCTATAA
+TTTTGGTAAAAATCGCTTGTATTCTGAAAAAAGAACTCAATATTTAATTT
+TTTATAACTGATTTTAAAGAGAAACAAACGAAATATATGAAAAAATCGAA
+AAAATCCCTGAAAAAGGCCTCCGCAATATTGATTGTTAAAGGGACACCGA
+CTGTTCATCGAATGGGTCCCGCCGCGATTGTCCATTTCGAGCGCTTTTCG
+CGATTTTTTACTACTGTAAAAAAGTGTAGGAAAATGTCGAAAAATGTCGA
+AAAATGACGTCACAAATGTATTTAAATACATGTTTTTATTGTTACTTGAA
+TAAGGCAAAATATGTATTTAAATACACTTTAATTTTCCGACATTACTTGA
+ATAACCCCATAAAAAACCCCGAAAAAATTTTTTTTTTGTGAAAATAACCA
+GAAAAATACATGTTAAAACAATTTTGTGAACAAAAAACTAAAAAATATTT
+TTTTTGCAGAGATGAATCCCACGTGAACGTCGAATTTCCACGCCGCCTCG
+TCGAACGGAATTTCAGAAGAATCGCATGTGACACGTGCAAGGAGGCGTCG
+GCTCAGTGAGTACAGAAAAATCCATGGGGATTTTTTAGAAATTCGGAATT
+GATTCGATTCAATAAAATCGATTTTTATATTAAAAAAAAGGATTTTATTG
+GTTTTTAAAAAATTTAAGAAAAAATTACAAAAAATCTATAAAATCGATTT
+TTTATTTAAAAAATTGAAACTCAATAAAAGTTCTTTCTAATTTTAGAAAA
+ATCGATTAAAAAATAATGTTTTAAAAATCAGTAAGAATCGATTAAAAATT
+CAATTTCATCGATTTTATTTATTTTAAAAAAACTTAATTTTTATGAAAAT
+CGATCATATCGGAGTCCAAAAAATAATTGGGAAAAAACTAAATTTTCAAG
+AAAATAATCGAAAAATTTTAATTTTGTTCAAATAATTGATAAAAACTCAT
+TTTTTAGGTTTTTTTTCAAAAAAAATTTGAACAAAAAACACATATTTCTC
+GAGCTTTTTTTCACAAATTGACCCGATTTAAATTAAAAATTCATAAGCTA
+AAAACCTTCTTTTTTTAACCAAAAAAAAAACGAAATTCCCAAAAATCATC
+AATTAAATCCAATTTTTTCAGCTGGATGATCGTCGACCACGACAATCTGC
+TTCCCAACTCGCCAGGCTATCTGTGCTCTTCGTGCTACAAGGAATTCTGT
+TTCGACGTGAACGGCAACAAAGTGTGCCAGTTTAAGGCCGTACCGTATTG
+CGATCGAAAGGACATTGGCGACGGACGCCAATTCTTCACCGAGCTCGATC
+TTTAGAGAGCGAAATTTAAAATTCTGTATCATTTTTTGTTGTTTTTTTTT
+ATGTTTTTCGATTTGATTGTTTAATTATCAATTTTTGGCCTGTAACTGTG
+TATTTGTTGAAATTCCAAATTTCGTTTTTTTTTTAAATAAAATTTCTGTG
+TGCAAAAAAATTTATCCAATAAATAAACGGAATATATCGATGATATGGCA
+AGTAGGGGGAAACGGACGGGAAAATGATTATTTACAGAAAGGGCGCGCAC
+CAGAGGTTTCTCGGGGGAGCCCCGAGGCGGGTGGCGGAGCTTGGCTCAAA
+ATCTGTCGGAAAAATGGGTGAAATGAGAGAAGAGGTAACCTAGAAAATGA
+GATGAGAAATTCGGAAGTTTTGGGAAAAAAAAATCAACTTTTGAACAATT
+CAATTGAAAAATCGATAATATTGATTTTTTTAAAATTCTCTAAGATCGAT
+AAATCTGGTTTGGAAAAATCAATAAAATCGAATCTTAAATATCTTTTTAA
+AAAACTATTTTCAAAAATCAATAATATCGATTTTTGAACAATTTGAAAAA
+TCGATAATGTTGATTTTTAAAATTAAATTTTATTGATTTTTTGAAAATCG
+ATTATATTGTTGATTATTGATTTAAAAATCACCAGAATCGATAAATCTGA
+TTTGGAAAAACCAATAAAATTGATTTTTACAAAAATCAGCCAATAAAATA
+GATTTTTTATAATCAAAAAAATCTATTTTTAAAACCGAAAAAATCGATAT
+TTCAAAAATTGAAAAAAATCGATAAATCAATAAATCAATACATAGGTGAG
+CTCGTCTCGTCGATTTGTGTTTTTGTGATTGGTCCCGGCTGCTTTTGAGA
+TGGCCTAGGCGTTGTTCCGTATGACATTCTGGAATTTTTTTTTGTTGGGA
+ATTTGGCACGCCCACAAAATGGACGGTGGCGGAAATTTAATTATTTTAAA
+TACCTTTCTGGATAAAAAAAATCGATTTTTCCACTTTTTCGAGTGAATCG
+AAAATTAAAAAAAACATTCAAAATTGTTTAGGGTCTCGCCACGAAAAACT
+CACAAATGCACGTTATGCGGAGTGTCGTCGGATTCCGGTGTGTTGCTACG
+GATCGTGTCGTCCATGCTCAGCTTCATCGTCGATTGACGTCGCCGTTTTG
+TGGTGATCTGAGCGAGATTTATTGATTTTTAAAGGCGCATGGCCTAGAAA
+ACACAACACTTCGGCCACGGACTTTGGCGGCCGAGTTTTCTAGGCCATGC
+TGCGGCATTTAAAGGCACATACCATGATAATGAAGATCGCCAATCCGAAA
+ATGATGACCAATGCGAAAGTGATAATTACAATCATCGATGATAAGGAATA
+TGATGAAGTTTGCGTGGAAATCGAATCGATGTACGCTTGTGACGTCATTC
+CTGGAAATTATTGATTTTTTTTTGGAAAAAAATTAATAATTACTTACCGT
+CAACAGTAACACTCAACGAGTCAATTTTGTAATCCGAAATCATAGAGTTA
+TTGCGTGAAAATGCGGCTTCCAACCTGAATGTTAAAAAAAAATCTATAAT
+ATCGATTTTTTGAAAGTTTTTCGAAAAATTGATAAAATTGACGATTGATT
+GTTTGCCCATAGAAACAGATAAAAATCGATATAACTTAATATCGATTTTT
+TTTTGTGCACCTTTAAAGAGTACTGTAACTTCAAACTTTCATTGCTGCGG
+AATTTTTTTATCGGTTTTTACAATTTTTTGTACAGTTTCCGTCCAATTTT
+ACAGAATTGAACAACAACAGAAGGAAAAGTGAAAAATCGTAAAAAATGTC
+CGCAGCAATGAAAGTTTGAAGTTACAGTACTCTTTAAAGGCGCACACCTT
+TTTTGTTTTAACAAAAATTTGTCGTGGTAAGACTGGGGACCGTTTTTTCG
+GCGGAGAAGTCGCAAAATTTCGGCTAATATCGAAGAAAAATCAATTTCCA
+ACAGCAGCGACACATAAAAATTAGCAAAAAATTGTGATTTTAGCCAAAAT
+TCAGTTATTTTTCGGAATTCCCGTGGCGAGACCCATTTCTCCCACCTGTA
+GAGCCAACTGCACAACTCGACATGCGAGTTTATCCTTGCAGATGGCCAAA
+AGCCCTCCGTCGATCATTTGACGAAGCAATTCCCGCTGCTCGGCCGGTGT
+TGCGAGCTCGACGAGCTTCTGAACGATGAAATTGCCATTTCGACTGTGGC
+AGAGCCCACGAAGAGCGTCGTGGATTCGGTGAGCTTCTCGAAGACGGCTT
+TACGAATCTGATCTTCGGAATCCAGTGGGTAGTTGGCCTCCAAGAACTTT
+ACGCCCGATGGATCGATTGCGAAATCGATGAGCTGCCCGTTGAGCAGCAC
+ATCTTGGAGCGAGATGGTGATCGGAGCCACTGGTGGTGCAGTCTCATCGT
+CGGAAGATCCAGATCCGAAGGTGTAGCTGTCAGAGTCGGAGGAGGTGGTG
+TTGCTCCCGTGGCGGTAGGGAAGAAGCTTGACCGGCGGCTTTGGGTTCTG
+GAAATTCTATATTTGAATTTGAAAATCAACAAAATTCAATATTTTACCCT
+GCTCTTGTGAGTTTTGTTCGACAAAAGCGAAAAATCCGGGTCGAAATCGA
+ATGAAACGCCGAACATGGGGGCCATTTGGACAGAAATGAATGAATACAGG
+TTAGTAGACGCTGAAAAATTGGGAATTTCAATTAATTTAGGATTTTTTAA
+CGGAAAAATAAGTGAAAATGAGAGGCAAACATGCAAATTAAAATCGCGAA
+ATTACCGCGCTTTGAAAGGGACTCCACCGATCGGAGAGACGAGGGAAGTG
+GAGAGACGCAAATCGAAGAGACGCCTTTTCAGACATTTTTTCGTGATAAT
+TTTGCATGAATTGGCAAGTAGAGCTTACACGTGATGCGAATCATTGATAA
+AAACATCAATTGTTGTTTTTAGTGTACTGAAATTCCGGCACAATAGCTCT
+CGTAAATCGACACAAAAGTCACTCCGTGGAAAAGTGGAATTTGGATAATT
+TTGTTCTTTTTTTTAAATATGATTAACGTTTTTGAAGGCTTTTGTCTCAT
+AATTCATCAAATTCAAAACCGGAATTATCCAAATTCCACTTTTCCACGGA
+GTGACTTTTGTGTCGATTTACGAGAGCTATTGTGCTGGAATTTCAGTACA
+GTAGAAACAGAAAATGTTGTTTTTATCAACGATTCGCATCATGTGTAAGC
+TCTACTTGCCAATTCATGCAAAATTATCACGAAAAATGTCTGAAAAGGCG
+TCTCTCCGATTCGCGTCTCTCCACTTCCCTCGTCTCTCCGATCGGTGGAG
+TCTCTTTTGAAATTCGAAAATAAAAAGTTTCGCAGTGCGCCCGGGTTACG
+GTGAATTTTAAAAGCGCATCACGGTTTTGAGTGAGGTCTCGACGCGAAAT
+TAGCCGTTTTTGAAGATTTGTCGTTTATTTTGGCATTTTTGAAGGAAACA
+TAAGTGAAAATAAACAATTTTAATCTTAATTGAGAGAAACTTGAACATTT
+TTACAAAAATTGCAAGAAATTGCGCGTTAAAATTCAAAAATTAGAAGTAT
+CGCGGCGCTCAAGCCGTTGATAACAAGCCGTTATAAACTTATATAACTAT
+ATAATGTAACTCGATGATTTGTTGATGTGATCTTTAAAAAGGTTGAAACT
+GCCCCAGTCGATGTCCGCGCCAGAGGCGCTGTCAGCGGCTGGTTACTTAT
+ATATAAAAAATATCGGGAAAAACGCACTTCCGTTCCATTTGTTTCTTTGT
+TTTTGTGACGTCACTGAGAATTATGGGCGGGCCCGTCTGCCTTCGTGGTA
+AGACCCATCGTGGCGAGACATATCGTGGTGATATCCTTCGTGGCGAGACC
+CATCGTGGTGAGACCCATCGTGGCGAGACCCATCGTGGTGAGACCCATCG
+TGGTAAGACCCATCGTGGCGAGACCTTTCGAAAATTTGGTGGGAATTCAA
+ATTTTCTTAGAAACATTTTTTGGTGGGAATTCAAAATTTTCAAAGAAAAA
+CTTTGGCGGGAATTCAATTTTTCAATAAATAATTTTGGCGGGAATTCAAA
+TTTTCTAAGAATAATTTTGACGGGAAATTCAAATTTGTTGAGAAACTCGA
+GTAAATGCTGGAATGTTCTAGAACCTTCCTGGAGATTGGGGAAAATTTTA
+GTATGTTCTAGAACCATCGGCGAACTTAAGAAAATTCTGGAAAGTTCTAA
+AACCTTCTAGAAAATTCGTGAAAATTCTGGATTGTTCTAGAAATTTCTAG
+AAAATTCGAGAAAACTCTGGAACGTTCTATAGAACCTTCTAGAAAATTCG
+GGAAAATTCTGGAATGTTCTAGAAAATCTTGTTTGCCAAAAGCTCTCGGA
+AGGAACCGGAAAAGTTTCTTATGATTTGAAGAACGTCTAGAAACGTTCAA
+GAAATTTAGAAGTAGTTCCAGGAAACCTGGTATTTTTAAGTTGTAACTCT
+TGAAAACTTAGTTATATAATATTCATGTTGCGTTAAAAACTTCTGGAAAA
+CTGAGAAAAACGTTCCAAGGCTTAGAAATTTTAGAATTTCATCTTAATTT
+CGAGTACGCCAGTCGGAGCACGCGCATTGTGCGAACGGCTGGTATACAAA
+CAATAGTCAGTCAATCCCATGGATCAAATTTTGAATTTTTCTAAGACTGA
+ACTGTTCCTTTGATATGCAAAATTTTATAAAATTGTCTGTTATTGAAAGA
+CATGAAACAAACTTGAATTACAGTAATTCTGTAAATTCTGAACTTACTAT
+TAGAATCCTTAGTGAGCACACTTGAAAACGAATGAAATAAGGTATGTGAG
+AATACCGTATCAATCAGATACGTCTGACACTTCCCCAAAAAAAACTATCA
+GAATATGAGTACGATATGTTATTACTAGTGTGCATCTTTCCGCGCGACCA
+TCATGGCTCAGCAGGTAAGACTTCGGCGACGCCTCGAGACGACGAGGTAG
+TTGACGACTTTTTTCATTTTTTAGGCAGCGCCCAACTCTTGTCCGAGGTC
+TACAGGCTACATGGTTTGGACGGACAGAGTATTTGCTTTATTAGTAGTAA
+CAGAAATACACATAAAATCAATTAATAAGATCCATGAAATGCAATAAAAA
+TCCAGTTTTCACCCATCTACTATGTCTCTCATTGAAGAACTTTTTCAGAT
+AGCTTTTGGTATAGAATATATTAAAATTCATTCTTCGATTTTCTGTGGAA
+TTTCTTATTTGAAAGCTTTTTCCATACCAGACAGTCACTTCTCCAAATCC
+ATCCTTGAAATTTTCTTTGGGGATATTTAAAATATCATCGAGATACCAAC
+AATCTACTGGTTTTTCACCTACAAGACGTGCTCTTGAATTGAAAATGTCT
+GGGATATCCTCTGGAATATGTTTTTCTCCTTTGTCATGCTGATAGTATAA
+GTTGAATGTGACACTTCCATTTCTCTGGCTGTTTTGTTCAGTCAATCGGA
+TTAGCTTTGCTGTGACTCTGTCCATATTGTCCGGAGTAATGAGGAGATAC
+GTTTTAGGAAGTAGAACAGTCATACTCTTGGCTGGGAAGTTTCGTTGAAC
+ATTTGCAATCACATTGTCCATTGGTGAATAATAGTCGTTTTCCAGTTGTT
+CGTTCATTTCGAGTAACATATCCTCAGAGTATTGTAAATCGATCTCCACT
+TTTTCCAGAAGAACCCTCGAAACGGGTTGGGTGTTGAATGGTACATTGAA
+TACGGCATTTGAAAAGTCTTTAGACGTTTCCAAAATGAAATCCATATTTG
+AACTAAACATAGTATTAAAATGACCACTGTAAGCTTCGAACCGGAACTCC
+AGTCTGAAATCCTTAACATTCCACTTTGAAATAAGCTGGTATAAAAAGTC
+TCTTGGGATTGAAAGGAACTCTTTTCCCAGTATTAAAACGGTGAATGTGT
+GGCATGTTACCAATGAATTGAGGAAATAATTTGCTCGAGCACCAACTACG
+TACCGCCCTAGTTGCTTTTCGTATATGGTCCGATAAAACAACCTGTAAAA
+TGTAATCTTTATAATGTTCCTGAGCATATCATGTCAAGAGTGTCTGAGTT
+TTTCATCAACAAAAACAAAATTTGATTTTTTTGTTAATTTTCTAAACAAT
+CCGATTTTTGGTTTTCCGGAAAATTGAAACATCGAAATTTTCCGTTTTTC
+AATATCCAATTATTCGATTTTCCGATTTCCTCTCAGAAGAACGAAAAAAA
+CGAGAATAAAGTTTCCATGACATTGATCGCAGTGGGCTGTTTGTTTTTGG
+GATAACTTTAAGTGAAGGAATGGAGAGACTATCTAAGTATGAAAAACACG
+AGAATTCACTCTTTTGAGAACCTGTTACAATACGTGTACTGTTATAATAG
+AAAAACTAAAGCAGTGATTCAAACATCTGTTCGACGGTGTTCATTACAAA
+TGTATCAATTTACACTCACCAGTCTTTCATTTCCAGCGCTTTGTAATGAC
+GTGGAGATATCCTGATTTGATTTATGATTTCTATTATTTTTAATTCTCCA
+AATAGCTCTTCTCCCAATATTCGCAACTCATCAATTCCAAAATTGCTCAA
+TCGAAGATATGCGAATTTCCCGAATAGTTCGTTTAATCTGTCCATAAATC
+GATCATGCTCATCAACTCCAAAATTTTCCAACATCAAATTCAAAAACTGC
+TGCGGTATCGAATTTCCACCAAAATATTGAAGTTGAATACTATGAACTAT
+ACAGTTTTTATTTCTATGAATGTCTCGACATATTTGACAACCACAGCAAA
+AATCATTTTTATATTCTTCAACGAGTCCATCTAAAAATCATGAATGTCAA
+ATCAGTAGTTCAAAAGCCATATATTTTACTCAGAATTCTGAAAAACAGGC
+GCTCATGTCAAAAATTGACTTACAATCTACTCCAATCAAGCAATCGTGTA
+TGAGATCATTGAGTATAATTCGAGCATCCACTCCGCACGAAATTTCGTTT
+TTCTTAATCGGTTCGACATAAAGCTTGTAGACTTTCACATTTACCGTATT
+TTTTAAAAATCTGAAAATAATGTTACAGCTGAGTACAAAACATTAAAAAT
+TGGTTTAATTGATTGAAATTTTCACCACTTCTCATATTGTTTCCACGATC
+ACAAAAAAGCATAAAAAACTTCAACAGACTCAGAAAACACTTTTTAAAGG
+CAAGTTTTGAACCACCTATTTTGATGAAAAATTGTCTGAAACACTTCTCA
+GATCGACTTTTCCCTAGCTCAAAGTGATCCTCTGCCGCTAGCTCTTTTTT
+AGAGTGGTCATTCGAAAGTCCGGGTTTAAGTTGAAATATTTCCCTTACCG
+GTCAAAATTCTATCAACATCAAAATAAAATTGAATTTTTTGGTAGTTAAC
+AGAGGAAGCGGCGAGCAAAAAAACCAGGTTTTGAACAATTGATTTCAACT
+TACACGAATAAGTGTTTCACCTTGTTTTTGTTTATCTCCAGTGCATTTAT
+AAGAAACGAGCAAGTGCATCGACGAAGCTGTTTTAGCGGAAGTTCAGGAT
+CTACTTGATTGTTAATGAATATTGATCTTTTTCTTCAATTTTTACAAGTT
+TTGAAACTGTGAATTTGTATTTTTCGATGCTCATTTCGAATTTTGTGCAA
+AACTTCTTCGCTGAACAATTTATTTATCAGCTGAAAAAAGAGCGAATTAA
+AGTAAAATTGAACACAATTTTGATACCTGTCTATAATTAGGGATATCAGT
+CCGCTGTATTGATTTTTTTGTTTGAAAAACTGAGTTTTTGTTTATTTGCA
+GCGGCAAATTTTTATTAATTTTTTTTGATAAAAGTTCATCAATGCCATCA
+GTGTTGTGGCACCACGGAGTGGCGGAAGACCGAACCCTTTAAGCCTCAAG
+AGGAACCGAGCAACGAAGACTATGTCAGAGGTGCAGCATGGCATCGTCTA
+TTTGTATATGTATTGGAAAGAACAGAACACAGTTTCAATAAATATGTTTA
+TTACTCCAAAGGGGAGATAATCAACAGAGGGGGAGTGGGTCGTACACAAG
+AGAGAGGGAATTGTCTGGTGTGAGAATATCACGTCCTGCCACGCGGGTCT
+TTAGTCTGAAAAGGTCGAGTGTATGAATAGTCGGGGTCTTTGCAGACTCG
+TAGAATAATGTCTTTGGTCAACTACACTTTCCAAATAAAGGGAGGGAAAG
+GTAGGAAACGTCGGCAATTAGTCTGACTGGGAGCTGTCAATAACGGGGGG
+GGGGGGGAAGAGACCAGCAAAACCGAACCAAGAGTGGGGAGGAGAGTTCC
+TTTCCTGGTGCCACCGACGCTGCAGCTCGCTCCGTATCGTCGCTCATTGA
+GTCGCCGCGCAGCCAATCGTTGCTACGGGGCGCGAGTGTAACTCTCGTTA
+GAGAGCGTGTGGGAGCAAGAGACGCAGAAATACAGTAAACTTCTGCGACT
+CCTAACTGTATGGTAAGCTTAAGAGCTGGTCTTAAAAGGTCGAATTGAAT
+GTACCCCTCGCTCGGAGAACTGCTGAAGCAGTCGAGAGCGAGACATTGTG
+AAATGGGCGATACAGCAGAGCCCAGTTCACAACTCTCCGGGGGGCGGGAC
+TTGTAGGCTGGTTCACGTAGTGAACTTAAGGTTTGAAGCCTTCCTTTGCC
+TTTCTTGGAAGAGATTGGCGGAGTGGAAGGTCGTCTGAGCTCCTGGCTTC
+TTTTCGTGAGCGTTCAGCTTCTTTTGAAGATCTAGTATTAGGTGAGCTCG
+GAGCTTCTTTTCTAAATCTTGCTTCGTCTGAGCTTAAAGCTTCTTTCCTG
+GATTTAATAAATTTTAAAGATGGAAGCATAGGTAGTGAGGGTTCAGGAAA
+GTCGGAGTCCGTCTCTTCGTCTTTTTGTGGAATTTTGTCTTTATTGTCTA
+TGTCTTCCGCTGTAACCTCAAGAGGATACAGTTGATTTAGTGATCGTTCC
+AACGTGGAGTTATTGAAACGAACTCGTGCCGATTCAATGTTTCCTTCTTT
+ACTCGGAATGAGCTCCACAATTTTGCCCAGAGGCCATGTGTGTCTTGGCA
+ACATTTCTTGTCCGACGAGAACAATGTCTCCTTGTTTAGGATCTCGAGGA
+GCATCCCTTGTATTAGTCTTTTGTCTTTCTCTCAGAAACAGGAGATATGA
+TGTCGACCAGATTTGCCACAACTTTGCAACTGTTGTTTCAACTCTGGCTA
+AGTGTCTTCTCGTGATTTGCTCTGTTGATCGAGCTGTCTTTGGAGAATAT
+TCCATCGGTTCGTCTAGATCAACTTCATTCGGTGCATCTAGCTGAACTTT
+TGGTAGTAGAAAGTCGATTGGGCGGAGAGCCGTCAGATCATTGGGATCTG
+TGTTGTCTGGTGTAAGTGGACGGTTGTTAATCATCCCTTGCACCTGTCTT
+AACGTGCTGGACAGCTCGAAGAAGGTTAACTTTTTTTTGCCAATAGTCTT
+GCGAAGTTGGTGCTTCGCAATTCCAACAATCCTCTCGTACACTCCACCTT
+GCCAAGGGGCGAATGGAGTGATGTTGTGTACCTGAATTTCGTATTTGGCT
+AAAAAGCAAATCATTGAGTTGCTTGGTGCGTAAAGTCTGATGTCTTGGTT
+GACCATTTGGTGGCCGAGTGTAAATGTTGGTGCATTGTCACAGTAGATAT
+GGGGCGGAACACCACATGCACTGGAGATTGCTCTGAGTGCGAGCAAGTAG
+TTGGCTGTAGTAGCGTCTGGAATGAGTTCTAGAATGGTAGCTCTAGTCTT
+CAGACAAGTGTAGATAAGAGCATAGGCTTTACCTAGCTTGTCATCGTCTG
+TCTTGTATTGTATTGGACCCAAATAGTCGAGTCCTACATGGTCGAATGGT
+GCAGAAGGTACAGTTCTGCAGTTTGGTAGTCGTGTGTCGTAATTGTATTT
+AAAGGGTCGTGCTTTCACCTTTTTACAGTTCACGCACTGAGCAATTGTAG
+TTCTTGCAATTTTGCGATCATTTCTGATCCAAAAGTGCAGTCTTACCGTA
+GTTGCCAAATAGTGTAATGGTAAGTGGGTATTTCGTCTGTGGACATCTTC
+CACAATTAGACACAATCAGATGTGGAACCGGATTGGGTCCCACTATCCAA
+TGATGTTTGTTTCCGTCCTCGTCTACTGGGTTACGCAATGTGTCTTGCAA
+AGTGATTAAGTAACCGTCTGTAACAACTGGAGAAGTTGTGTCAAAAAATG
+TCTGAATCAGTATGATTTTGTCTCTGTCTTTGAATTCGAGAATTCGTATT
+GTCTTGCATTGACTGAGCATAAGAACAGTTTCCTGTTATATGACTCGGTG
+ACGAGCAAATCGTGCATCTACCATTGTTGATGCAGAAGCGTTTGACTTCA
+ATCGCACCCATTGTGCACGTTTGAAGTGGATGGTCTTTTTTGCAGGGAGG
+GCACGGATCTCCATCGAGAAATTCTTGCCAATTCTCCACGAGTCTGGAGG
+TAGTATTACCCGTCTTTTGTTGAATATGCAGGTTCAGGAGGTTTTCCTTT
+AGTTTTCTGTCCCGTTGGACATCAACCAAAGTACGTCGCCAATCTTCCGC
+GCAGTTGTCTTCAAGATGTTTTTTGAGGCTTACGATTGGATCGTCAGCCC
+GTCTGGGTCGTATAAAGTTACGCGGAGTCAGCTCGGTATAGTCAGCTTGA
+TAGTCTTGCATATAGTCTTTGAGATCTTTAATTATCATGTCTTTGGATTT
+AATCGTTGAAGGTTTCTGTTTAACAGTTTCCAACAAGTCTTTAATCGTCG
+ATAGTCTATGTCTCAAGTCACCAGAAATAACAATCATTTTCTGTCTGGCC
+AGATTAGTCGTGGATCGTATGATATCTGTTAAATTCAAAATTGGCGTACC
+TGTATCCTTTGCCTTCTCGGCGACGTCCTTGAACATCTCCTCGATGATAT
+CCGGCAATGAATTGGCTTCGACCAAGTATTGAGTCAGGTCTTTGTACCAT
+TTGTGAAGATCCTTGATGTAGTCCATATGCTGCTGCTTGTCACAATCGAT
+ATTGGCGTTAAGCCAGTCGGATGAAGACTTATCTTTGTGCTTCAAGTCTT
+CAGTCTTAAGTGCGATACGCGTCAGCAACAATGCTATGGATGATGAAGTG
+GAGAATGGGGTCCTGGATTCCCTTCCCAAGCTGCCACCACCGGAGTCGGG
+ATCAAGACTTCCACCTCCAAGATGAAAAGTCATTCTTCTTTGAAAACCGA
+GAAACTTGTTATCTAAAATCAATAATTGGTTAAGAAGAAAGACAAAATGT
+TTTGAGATTAAGTAAAAGACTTAATAAGAGATTAGGAAAGAAAGATGGGG
+ATGAAGACTCAATTTGAGTGATAAGAAAAAAAGGTATTTTAATATAAGAT
+TCTACAATAGGGATTGGGAAAGGTGTGCCGTGGCCTAATATAGGTTTGGT
+GGTACAATAAATAGGGGAAGTAATGACCCAATATGGGTGGGGGGATTATT
+AAATGTTACCTAATATGGGTGAATTATTAATTATTCCTTTGGCAGAGGAA
+TGTCGGTGAGGGCTAAGAGTTCCCTGTATTGTAGGTTGATTAGTCATGTA
+GGGGACTGGTGTAGAGTAATTTGGTGTAGAGTAATTTGGTGTAGAGTAGG
+TATTTGGTGTAGAGTAGGTTTTGGTGTAGAGTAGGTTTTGGTGTAGAGTA
+ATTTGGTGTAGAGTAATTGGTGTAGAGTAGGGATGGAGGGAATTCAACAC
+CGACTGGTCGTGAATCAGATCGGCCCTGAATTGGGGTAGGGGACAATAGA
+AAGAAACTACCGTGTGGCCAACTGCCCCCAGCAGGGACCTAGTTGGGATT
+GTTTTCACTTGAACACGAAAACAATGGGGGTTGGGAAAGTTAATAGGGAC
+AAAGGAGCAAAACGAAACGTCCATTCCCGCATCGAATTGCCTCATAGGCA
+CCGCACCCAAACTCTCCTGCCGCTGCAGCAGTCAGGGAATCCGACGCTCC
+ACGCTCTCCATCGCGACTGGAGACCAAGTTCTTCTTTCTTCTTATAGTCT
+TTTTTTTCTAGTGGCGCCGGTTAATTACTCCATTGCCAACTAGCTGTCGG
+GAAGTCAGAAGTCAAATGTCCTTGCGGACGTGGAATATAACATGTTTGAA
+ATTAGGGTGGTTTAAGTTTTTTGTGAGATCCCTATGGATAAATTTTGGTT
+AATTTTTAAATTTGAAAGGTTTTAAAAGATGTACAAATAATTTTTAATGA
+TGTATAATTTTTGGAGAAGGTACTAGTTGAAAGATATAAAGAATTTTTAA
+ATTGAAAGTTAAATTAAAATTTTGAGGGGAATTGGTGTAGAAAATTAGTT
+AAAATATATTTTTGGAATTTTTGAAATTTTATAATTTTTAAGGATTTTTT
+AAATTTTTTAGGAAGTTATAAAAGGGGGTAAATAAACTAACTGTTCGATC
+GCCGCGTCCTCCAACGAGCAAATCCTCCATCCATCCAGAGTTCTTGTCTA
+CCCGTCTTGTCGTCTATTCCTCCTTTTCTTCTTGTCTCTAGCACACAGGA
+GACTGTGCACTATTGTCTTTCCGTTGCAGTCAGCGAGCTGCCAGCAACTA
+GTCGCATCGTTAATGGCACCTTTGCCACTGTATTGAATGCTGTGAGCTGT
+TTTAAGTGCTATTACACTATAGTCTGTAGAAAACAAGAAATTTTGTAATC
+GTCTTTCGTCTTTCGTCTTGAACCATATTAACAGCCGAGATTTATTAAAT
+CAAGGAACAAATAACAGCTTCAACAATGTGGTATCAGATACCGGTGAGGA
+GTGGTGAGGGGGGAATTTCAAAAAATTTAAAAGATAAAAATTTAGTGATC
+GAATATCGAGATATTCGATGGGGATTGTCCTCGTGCCAATTTCTTGGCGA
+TCCTTGGTTGGTATCGGCGTCTGACCGGCTGGTGTTGTTGCTGCTGTTGC
+TGGAGTTGTGGTGGCGGTGGTCCAAATAGTTGTGGAGCAGGAACGCGAAG
+TGGTGGTGGGAACTCCTGTGCGGCTGGTACGAGTTGTGGTGGAGGTTGCT
+CTTCGGATGGTGGTGGCGTGTGAGCATTGAATCCTCCAGAGACTTCCATC
+GCGAGGGAGATCCTGTTGATCGCTGCGTGCACCACATCTATCTTGTCGTA
+CAGAACGACGTGATCCGCGGATTGGATCCACACTTCCTGGGAGCCAGAGC
+CTTGTGGAGCCGTCGCAGTCGTCGGGCCATTTGGGTCGCGGCCGGTCTGG
+GGGGCTGGGCCCGTACTTCCTGGGAAGTTGAGAAACCAGTCTTCGAAGAA
+CTCGGATGGAGATGTGTCGTCGGTGAGCGTCGGGTCGAACGGTCTGAGAA
+GATTTTAGAAAATTAATAATAGTATATGGAAAAATTGGATAAATTTTTAG
+AATTTTGAAAGAATTGATTGAAAATGTGTATAAATTGAATTTTTTAGAGA
+AAAATGATAAAATTTTTTAGAGAAAATAATAATTTTTAGATAATTTTTAA
+ATAAAATCGAAACTTCCTTTAGTCTGGCGCTTCGTGGATGGGTAGGCTCC
+ACTCAGCTGTCAACTTACGTACTACCAATGAAGAATTGCAGGATAATGTG
+CATATTAGATGCAAAACGACGAGAAATAGCGAATAATAAGTCGGGGAAAG
+TCGAAATTGTGCTCTGGGAGCATGAGTTTGCCAAACTCACGTCCCTCGGC
+GTCTGTGGGCTCGCGAGCCGCCCTTGTGTACGATTTTAGGGGTTTTTTAA
+TTTTGAATTTTTAGAATTTTAATTATTTTTAAAGAAAGTTTGGTAGAATA
+AAGGGACGGGGGATGTTTAAATAGATGTGTACCTGTCGTCTATCAAGTCT
+TCGACTATCGAAAACGTCGAGTCGTCGAAGTTCATATTGAATCGTCTCTT
+CACGGCCCGGCGGGGGGTACATGGACGAGAATTCTCTACCGTATTCCAAT
+TTGGCTGACTGCGTGCTCAACGTTGAATACTCAGTTTAAAGTTTCGTACA
+CCGTTGCGTACTGCACAGCGCGCATTTTAATTGACGAAATTTCGCGAAAA
+TTAACAGAAGATTTTTTTCGGAATTATAGAGCTGAAATTGAAAAAAAAAC
+TATCAAATTTTCATCGAATTTGTGAAAAATCGTAAGTATGAAGATCTTTT
+CTTCACTATATTCAAGGAAAATCGATATTTCGCTTTTCACAGACGAATGA
+TGTCTCATTTTACTCGATGAAAGTTTCTGATGAGCTGTTTTTATCGATTT
+TTGAGCGATAAAAATGCGATTTGTTGATAAAATGGATCAATTATATAAAG
+AAACAACATATATTGCTCTGAGATTACTTTTTGAGAATCAATTCTTTATT
+TTTCGGTCATTTTAAATTAAGCATTAAAATAAAAATATTAGAAATCATAA
+TAAAAAAAACAGAAAATCGATATATTACTTTTTCTTCGGAATTTCACGAC
+TTTTTTGGACGAATTTTATTCTGTAAACTTTCTTCTTCGAATTTGTGTCC
+ACGTGGCTTTCAGTCGAAGAAGATTCTGCAGCACTCCTTCTTGCTTGCCC
+ACAACTTACTCGAATTTTCTAAAATTTTTAACTTATTGAAATTGTCATTT
+CACCTTTACACTCACTTCAGCTAAACTATTACTGCATTTCGGAAGTTGAT
+AGGATACTGGTGGAGCAACAAGTGGATGGCTTCTAGTGATTGGCTGGCTT
+GTCGAGCAAGTTTGTGTGATTGCCTGAAATAATTTTTGATTTCAATTTTG
+AGTTGATTTAAAGCAGTGAACCTACCACCGGGTTCGGACGAGAAAGAGCA
+TTACTCGGTAGACCACGGAATCCAATTTTCGTTGAATTGCCTCCAAATGC
+AATAGAAGTTTGTACGTTTTGTGAGAAGTCGGGCTGAAAATTTTCAAAAT
+TTGAAACTTTTCGAGAAAAATAAAAATCTCACCACAGCATTTCGAGATTT
+TGTCGATTGTGGAAGCCTTTTCCTGGAGCGAAAATTGATTTTTTTTTTCG
+CTAAATTTTTTCTTTTTTGGGCAGCCGTGACGTCCCGAATAACTGCTTTT
+GGGTCCCGAAGATCATTTTGCGAAGAAATTGGCAGAACTGTTGCATCTTT
+TGGTACGATGGAAAGACCGGGAATGGACGTGTTCTGAAATAGTTGTGTTT
+TTAAGAATGCAGAAATGTTTTTCTGTACCAAAATTACCATAGTCATGTCA
+TTCATGATGTTACGACACATGAGCTCTCTCAGAACATGGATGTAACGCCT
+TTTCTTGTCCCGGTAATTGCAAAATCTCCTCTCAAGTGCATTGAAAATCG
+CGTGGACAGATTCAACTCCTTGTTCTGTGATCCTTCCAATGTTTCTCACA
+TCTTTTGCCATTTGTGGTGCATGGTAGACCAACAAGTGCAGCTTTAAAAT
+AATTGTTTCTTCGGGAACCGCTACTTTCAAATCCTCCACAAATCCGCGAA
+TCGAATTTTGAAGTATTAAGACGTCGGAATCATTTAAAAACTTGTTTCCC
+GAAAGTGACATAATAGTTGAAAGCTTTCCCATTGCTGATTTCAATCCGAG
+CAACATTGGGCATAAATTTGGGCCAAAAATGTTGAAAGTCTCCTCTACAA
+CAGCCGGCGTTAGCAGCAATTTCAAATGGTTTCCGCAAAATGATTGGAAC
+CAAGCCTGCTTGTCCGCTCCAAACTTAGCCCAACACTGTCCCATTTTTTC
+AAGTGTTCCTTCGGGAGTACCATTCACAATTGTATCGAGCAACAATTTTT
+CCGATTGAAGTGCTTTCAGTTCAGCATGCGACTCCAATTTCATCTTTCCG
+GTGGCTCCTTGATACTTTTCTTCCGCACTTTTAATTAGGTTAACAGCGTT
+TTTTAGAGTTGCTTTTCGTGTTTTCAGGATAGGAAAAGAAGTAGTGTTAT
+CCAAAGTATCAGAATATTTCCAGAGGGGATTGAAGATATATTTGTCAAAA
+ATACCCATGATAATGTGCAGAAGAGGAATCAAATAGAACATGATCGCAAC
+GTGTGGCAGAAGTGGAGTACATCCTTTGCGAACACCCAAGTCGCCATTTT
+CACAACAAGCTTTGTAAAGATCGATTGTTCGTGGGTGGAATGTTTCATCA
+ACATTCATATCCTTGATTTTCATCCTCTCTTCAGCTCCCCGTGGATTCTG
+TGCAAAACATTTGAAGCAGAAATTGTGGGATGAATGTCCTTGGTGTCCAA
+GAATATCAGATTGAAACTTGCAATCTCCAGTTGCAATTTGCACAATTTTT
+GCGGTTTTTTGAACTCCTTTGTCCAAATATCAAATTTTCGTTAGCTTGCC
+AAGCTGCTCAAGAACGTCCGGAATGAATTTTTTCAGAGACGAATAATTGT
+CGGATCCGTCATATACTGCAATTACCATAACGTGTCTCGAAGAATTCGGT
+CGAGATACGTTTCCGATTACCAATGCCAACTTTGTGCTTCCACCTCCAGC
+GTCACCAACGACTCCAATCTTGATTACTCCTTTCGTGTATCCGTCGTCCA
+CAAATTGATTTGAATTGCATAGAAGCTCTATTCGATAGGCTAAAACTTCT
+GCAATTTTCATGCACTGCACAATGGTAATCACTTTTCCTTTATTGTCGAA
+CGAAGTGGAAACTTTGAAACTGGAGATCATTGATAACTGGATTGACAAAT
+CTCTTGTGTTCTTTACCGATGGAAGCAAATCATAGCCAATGGCATTAGTC
+AAATAGTTTTTGATTTTTTCCATCTGACTTAGAGATAATCCGCATTTTGA
+TAAAAAGTCAACGGCCTCAAAGTTTGAAAGCTTGTTTTTGTAGCTTTGAT
+TCTCTTCTGAATTCAGGAATTTTGTGAATTTTCGAATAAATTGTCCGACG
+TCATCCTCGAGGCAGATTTCGTGTTGAAGCAAGTGAAGAGCTTTGCGAAA
+TCGATTTTTGATACAACTTTTGCTTCTTAGATTCGAAATATTAACTTTAA
+AAGCTGATTTTTTAAGGTTTTCAACTTCTTCGGCGTGTCTTTGTAGACTC
+AGAACCATAGCTTTGCCACTTTTCTTCACATCTGCACAGCTTCTCACCAA
+TCGACCTTCTATACCACTGACGATCGTTCGTATATTGCATACTTCCATTT
+GCAGCGAAGAATTAGATGCTCTTATAGTGATATTTTCATGGCGGACTATT
+TGCATTTCTTCCGAAAACACCGCAAACTCATCAATCCGCTTTTGTATTTC
+TTCTGATATTTCATTTTTTTCATTTTTCAGTCGTTCGATCGTTAGTCGGA
+GCATTTTGATCTGCGGAATTTGCTCAACATTGGAGATTATTCGAACCCTC
+GGTGTACTGAACGAGTTTCGTAAAGGTGTCGGTGGAAATACGGGATTGGA
+GAATCTCAGCAAAATCATATAATATTAGTTTTGAAATATTGAAAAAAATT
+ACATTGTGAGAAAAAGTCGGAATTTCGTCACTAAAATCCATTTCCACGTC
+TCTCGTCAGAATTCCTTCATCCATATTGAAACAATTTGACGACCTGCATG
+TAGTTGCGGAGCTACTGGAAGCAATGTCGGGATGGTGGGAGTTTCGATCT
+TCTGAACTGATTTCCTGATTAGCCTGTGGCGACGAGCTGCACGTCTGAAA
+ATCACGTTTTTGAAGTTAGAACAAACTACTCCAACTTAATTAAAGTTGAC
+AAAATTGAGCTGAACGAACCTCCACTTTCGAATTGTTCAGTTCTTCCTCT
+TCAGTTTGATCTTTTGAAACTCCATTAGCACTGTTCCTTGCTCTCTGGGC
+ATTTGCTAAAAGAAGGCCTGCACAAGATTTTTCTTTTCTTTTTTGTTTGA
+AGTATACTTTTGTCATCTGGAAATATTGCATGAATATTATAAGGGAAACA
+ATTTTTAAATATCGATTTTCACGAAATTTGAAAAAATCAATAATTTGGGC
+GCATGATATTGAGCTGAATGTTTCGAATTTAGAATCAGCATGCTTTTATT
+CATATTTTAGGATCTTTTTAAAAAATCTGGACCAACAGTTTTTGAAAAAA
+AAATACTTTTCGTTCAGAAATGTACTGATTTTCCACTGATTTTCACGAAA
+TTTGAAAAAATCAATAATTTAGGCGCATGATATTGAGCTGAATGTTTTGA
+ATTTAGAATCAGCATGCTTTTATTCATATTTTAGGATCTTTTTAAAAAAT
+CTGGACCAACAGTTTTCGAAAAAATTCAATTTTTGTTCAGAAATGTGAAT
+ATTCACTAAATCGAAAAAAATAATTGCAAAATCCGTCGGCTGAACATTCA
+AAACTTATCAATTTGAAATCAGCATATTTCAGTGTATAATTAAAAAAGGT
+TTCAAAAATTCTGAGACCAATTTTTGTTGAGAAAAATAATTTTTCGTTCG
+AATTATCGATTTTTCACGAAATGCCAAAAACAGTAAACTTGGGCCCATGC
+TAAAAGCCTGAATCTTTCAAATTAAAAACCAGCATGATTTTTTCTATATT
+CTAAGACGTTTAAAAAAAATCTGGACCAACAGTTCTTGAGGAAAGTAATT
+TTTTATACAAAAATGTGCTGATTTTTCACTAAATTCAAAAAAATAATCAA
+GTTGGGCCCATGCTATACACCTAAATCATTAAAATTCAGAACCGCCATGT
+ATGTATTTTTTCATACCATAGGCTCTTTAAAAAAAATCTGGACCAACAGT
+TTTTGAGATATGTCAAAAAAAACAACTCACTTTTTGACGTTTTTCGCCTT
+TTCGCGGATGATGCGGTCGATTTTTGCGGCGATTTGTGGTCTTTCGCTGA
+AAATATTATTTTTATTTCAATTTTTAACGAAGAAAACAAGAAAAAACGAC
+GAGAAAACATCAAAAAACACGAAAAAAACGTCGAAAAACTCCCGCAACCT
+CATGAAAAAAAATAAAGCACTGCAGCCGCGGGACTAGTTTTCGCAACTTT
+CTAGGCCATGTCCCGTTCGCCGTGCCGTGTCTTGTCGTGGTGGTGTGAAG
+TGTGTTGGTGTGAAGCGTGTGAGTACGGTAGGCTGCTGCAGATGTGGTGT
+GAGCTGTAAAAAATCGAAATAATTCAAGAATTACGACGATTTTCGTATTT
+TGAGAAGAAGAAAATTTTAAATCACGAAAATTCGAGAGAAAAAATGATCA
+AATTCAGTCTCAGAAGCGAAAAATGAACTTCTTTGTCTGGAAAACAGCGG
+TTGCTCGTGAGAAAAAATGTTTAAAATTGAAGAAGATCAACAAAAACAAA
+AAAAGACACGTAAATGCAACTTGTTTTTAAAGGTCGTGGCCGCGTCGCGG
+TCGCGCCGCGTGCGCACTTTTGTAGAAGACTCCGCCCCCTTTTTTCTTGG
+CGCCGTGCCAATTTTTAGAAGGAAGAGCGTTTTTGGTTGAAATAATCGAT
+TTTCGACGAGAAAATAGACTAAATCAAGTATGGTGAATCTGATTAAAGGC
+ATATTAACTTTGTAAACTGCACAATTAACTAGAAATCGTACTATAACCGA
+ATATAGTCAAAGGGTCGCTCAGTTCCCCCGGTCTAGAGTCCCAGGTTCAT
+CTTTCGAGCTGTTTCCTGAGAAATTGTACAGGATTTGTCTGAGTCGTGAA
+CTGAACACGCTTTTCAGGTAAACGTCGTCTGGATGTCCTGGAAATCAAAT
+GTTAGTCTTTGTATCGATGGAAAACATGGTTTTCTCAAGGAAATAGTCGG
+AAAGTCGGTCGATGCACCATGTTGTGGCACCACGGAGTGGCGGAAGACCG
+AACCCTTTAAGCCTCAAGAGGAACCGAGCAACGAAGACTATGTCAGAGGT
+GCAGCATGGCATCGTCTATTTGTATATGTATTGGAAAGAACAGAACACAG
+TTTTAATAAATATGTTTATTACTCCAAAGGGGAGATAATCAACAGAGGGG
+AGTGGGTCGTACACAAGAGAGAGGGAATTGTCTGGTGTGAGAATATCACG
+TCCTGCCACGCGGGTCTTTAGTCTGAAAAGGTCGAGTGTATGAATAGTCG
+GGGTCTTTGCAGACTCGTAGAATAATGTCTTTGGTCAACTACACTTTCCA
+AATAAAGGGAGGGAAAGGTAGGAAACGTCGGCAATTAGTCTGACTGGGAG
+CTGTCAATAACGGGGGGGGGGGGGGGGGGGGAAGAGACCAGCAAAACCGA
+ACCAAGAGTGGGGAGGAGAGTTCCTTTCCTGGTGCCACCGACGCTGCAGC
+TCGCTCCGTATCGTCGCTCATTGAGTCGCCGCGCAGCCAATCGTTGCTAC
+GGGGCGCGAGTGTAACTCTCGTTAGAGAGCGTGTGGGAGCAAGAGACGCA
+GAAATACAGTAAACTTCTCCTAACTGTATGGTAAGCTTAAGAGCTGGTCT
+TAAAAGGTCGAATTGAATGTACCCCTCGCTCGGAGAACTGCTGAAGCAGT
+CGAGAGCGAGACATTGTGAAATGGGCGATACAGCAGAGCCCAGTTCACAA
+CAATCAGACTAACTGGCACTTACGTATAAATAATATTATGGGTTTCGTCG
+CTCCCCCTCCAAATGTTTTAAAAACGATTTAAAACATAATTTATACTGTT
+TTTTTTTACTACTGACCAATGAAAGTTCATGGTTGATAACATAAATCCCC
+ACATTTTCAGAAAAATGGATAAGCAGAAAAAAAGTTATTAATGAACTCAT
+AATTTTCATCGAAATTAGCCAGCTTTAGTTTCGGTGTATTACCAGAAAAC
+AAATTTAAGTGATCTTACTCTCAACTCCAACAGAGTATCTAATTGATTAG
+ACACATTTTTTACAATCTTGCTGACAATTGTGCGATTTTTGAAGATTTTG
+TCAATAAGCACGTGATCCTGAAAATAAAAAAGTGAGTAATTTTACGCTCG
+CGAAATTGTGAGCCAGTGGCTGCCTAGATTTTCAATTTGTTACATTATTT
+TGCAGCCATACGTGGACCATAATTCTGGCGACCACTTTACGGCATTATAA
+TTTTTTGAACTGCAAACAAAACATGTAAATATACATATATGTATACTAGG
+AATTCGCACTAAAGTAAATTATTGAAATTCGTCAACTTTTATTTTCATTT
+CTTATATTTTGTCTAATTTTCAACGAATTATTGAAAATGAAAATTTTTAA
+TTCACGTCAAAATTAGTGAACGCGGTGAACGGCGACGGCGAAGGCGGGCC
+GGCGTGAGGCCGGCGTGAGGCCCGCGTTTCGCGCCTCACTTAGCTGGAAA
+CCCTAAGTTTCTCCAATTAAATTACAGGTGATATACATTTTTCCTCTTTA
+GGATAAGAAAAGATCATTTCCTAAGCCTGACAATACAAAAATGTGGTTCA
+CGTTTTTATTTTTCATAACTTAAAAAAATACTATTAAAATGAGGGCATGT
+AATACACAAATACCGGCAAACGGTGTTTCAAATCAAATATTGAAGAAAAA
+ACAAACAAAATATGATGAATTCTCTTTGTTCTTACCAAAATCGAAACCAT
+CATTTAAAATTTAGCAATTTTTTACAGTTATATTTGGTAATTACGGCCCA
+TTTTCTATAATATAAAGAAACAATTGAAACTGATCCACCCTGTCCGCCGA
+CTATTGGGCATCGACAGATGGTGTTCTCAAAATACCAAAAATGGGTGGAA
+CTCTCTCACGAGCGCTCTGCAGGTGTCGTTTTCCTTTGCAAAGGACTGCC
+CTTCCATTCATTTGTGTCTCTATACAACATCTCATCTGTCATGCAAACCG
+ACATTCCCAACATACTCGAAATCCCAATTGATGTAAGTTCTTGTTTCTTA
+AACTAAAATTAGCCAACTATTTTCTAGAAATATCAATCTAGACCGAAATA
+CCTTTTACTCTTGAATGATATCAAAAGTTTAAAAATGTTTTATCTGGTAA
+ATATATTATTCAGTCAATAATAACAGAGCAATAATTTCCTATTTGTAAGA
+CGGTTTGCCAGCCCTACTGATGTAAGCTAAAGGTCCTACAAAAAATCCCT
+GAATTTTGGGTCTCCTTTGCTAACTACAAATGGTAGGCAAAAGAACATAT
+TTGTGTACAAAAAAGTATGCAAGCAAAAGAGACAGCGTAGGCAGGCAAAA
+GATTCATAAAAGAGAGATAGCCCCCGCGGTCAAATCATTCTACTAGTGGC
+TTGAAGCCTCTGTTGATGTGATAAAAGTAACATTTTATATAGCATTGTGT
+TCGATTTTTCTAACAAATAAAATGCATATCATTACTTATACAGTGCGTGC
+ATGTTCTTTATGCCACCCCCAAAGTTTTTAATCATGGCAGTTTCTGTGTA
+ATTTGGTGAGCAAAAAGTATTGAAAACCTATTCACAATGAAAAACCTAAA
+CTCAAGAAATGTTGTGATTATATCTCGAAAATTGTGAAAAATAAGACAAT
+AAATCAAAAATTGGCCGTGCAACTTCTATATGCCACCTCGGATTTTTTTA
+TGATTTCTTATGATTTTAGACTATTAACTTATTATTCAAATAAAATTCGA
+TTCAATTCGTATACATTTCAGTGCTAAATAACTATTCCTGTAACTTCTCC
+CAAAGACGATACGATGATCAAAATATGGGGATATGTTCTAGATACTAATT
+AAACATAGTATGTGAATATTGGTTCACATTGGTGGATTTTTAGCGTCGCC
+AGAGGGACATATTTGGTGTCCCCAGCCGTTTTTGGTGAAAACACTATTTC
+TCTTTTTTTTCTCGGTGCCAATCAAGTTGAGAAATTTCAGGCATGCTCTC
+GAACCTTCAGGAAAGATCGAATACTGCAGAAAACCTGTAGACTAGGAAAA
+CAACTTGGAAGTTTCTTAAAAGTTTGGAATTTTACTAGAATTTTCTGAAA
+AATTTCAGAAAAAAAGAGACTTTCAAGAAACTTCTGAAAACTTCGAGAAA
+GTTCTGGAATGTTCCAGATTTTTCTAAAAAGTAACAAATTCCGTTCAGAA
+CAATGTTTTGAATATATGCCAGAATCTTACTCAAGTAAAATAATTTTTTT
+TAAATTCTGATACTCCAAAAATATTATGAAATTTCAAAAAAAATTAAATT
+TAATAGACGTTTGCAATACTATTGAAGACCTGAAAAAATGTTAGAAATTT
+AGAAATTGTTCATTTTGAAGTATTCGAAATACTGTTCGATTATTCATGAG
+ACTGATAATGTTATCAGTTTTTTTTATTTGAAAGCTTTCTAAGAATTTCA
+TATGATTAGAACATCGAAATAGTTTTACTTTAAAGAAAAAATTGCTCCTG
+GAAAATTTTAACTGCTGAAAACTTGGTTACAGAAATTTTATGATGCTCAA
+ACACTTCCTGGAAACTGAAAAAAAAAAACGTTTCATCTGCAAAGAAAAAC
+TTAGAACAAATTTCAATAATTTACTTTAGTGCAAATTCCTAGTATACATA
+TATGTATATTTACATGTTTTGTTTGCAGTTCAAAAAATTATAATGCCGTA
+AAATGGTCGCCAGAATTATGGTCCACGTATGGCTGCAAAATAATGTAAAA
+AATTGAAAATCTAGGCAGCCACTGGCTCACAATTTCGCGAGCGTAAAATT
+ACTCACTTTTTTATTTTCAGGATCACGTGCTTATTGACAAAATCTTCAAA
+AATCGCACAATTGTCAGCAAGATTGTAAAAAATGTGTCTAATCAATTAAA
+TACTCTGTTGGAGTTGAGAGTAAGATCACTTAAATTTGTTTTCTGGTAAT
+ACACCGAAACTAAAGCTGGCTAATTTCGATGAAAATTATGAGTTCATTAA
+TAACTTTTTTTCTGCTTATCCATTTTTCTGAAAATGTGGGGATTTATGTT
+ATCAACCATGAACTTTCATTGGTCAGTAGTAAAAAAAACAGTATAAATTA
+TGTTTTAAATCGTTTTTAAAACATTTGGAGGGGGAGCGACGAAACCCATA
+ATATTATTTATACGTAAGTGCCAGTTAGTCTGATGGCATTGATGAACTTT
+TATCAAAAAAAATTAATAAAAATTTGCCGCTGCAAATAAACAAAAACTTA
+GTTTTTCAAACAAAAAAAATCAATACAGCGGACTGATATCCCTAATTATA
+GACAGGTATCAAAATTGTGTTCAATTTTACTTTAATTCGCTCTTTTTTCA
+GCTGATAAATAAATTGTTCAGCGAAGAAGTTTTGCACAAAATTCGAAATG
+AGCATCGAAAAATACAAATTCACAGTTTCAAGACTTGTAAAAATTGAAGA
+AAAAGATCAATATTCATTAACAATCAAGTAGATCCTGAACTTCCGCTAAA
+ACAGCCTCGTCGATGCACTTGCTCGTTTCTTATAAATGCACTGGAGATAA
+ACAAGAACAAGGTGAAACACTTATTCGTGTAAGTTGAAATCAATTGTTCA
+AAACCTGGTTTTTTTGCTCGCCGCTTCCTCTGTTAACTACCAAAAAATTC
+AATTTTATTTTGATGTTGATAGAATTTTGACCGGTAAGGGAAATATTTCA
+ACTTAAACCCGGACTTTCGAATGACCACTCTAAAAAAGAGCTAGCGGCAG
+AGGATCAATTTGAGCTAGGGAAAAGTCGATCTGAGAAGTGTTTCAGACAA
+TTTTTCATCAAAATAGGTGGTTCAGAACTTGCCTTTAAAAAGTGTTTTCT
+GAGTCTGTTGAAGTTTTTTATGCTTTTTTGTGATCGTGGAAACAATATGA
+GAAGTGGTGAAAATTTCAATCAATTAAACCAATTTTTAATGTTTTGTACT
+CAGCTGTAACATTATTTTCAGATTTTTAAAAAATACGGTAAATGTGAAAG
+TCTACAAGCTTTATGTCGAACCGATTAAGAAAAACGAAATTTCGTGCGGA
+GTGGATGCTCGAATTATACTCAATGATCTCATACACGATTGCTTGATTGG
+AGTAGATTGTAAGTCAATTTTTGACATGAGCGCCTGTTTTTCAGAATTCT
+GAGTAAAATATATGGCTTTTGAACTACTGATTTGACATTCATGATTTTTA
+GATGGACTCGTTGAAGAATATAAAAATGATTTTTGCTGTGGTTGTCAAAT
+ATGTCGAGACATTCATAGAAATAAAAACTGTATAGTTCATAGTATTCAAC
+TTCAATATTTTGGTGGAAATTCGATACCGCAGCAGTTTTTGAATTTGATG
+TTGGAAAATTTTGGAGTTGATGAGCATGATCGATTTATGGACAGATTAAA
+CGAACTATTCGGGAAATTCGCATATCTTCGATTGAGCAATTTTGGAATTG
+ATGAGTTGCGAATATCGGGAGAAGAGCTATTTGGAGAATTAAAAATAATA
+GAAATCATAAATCAAATCAGGATATCTCCACATCATTACAAAGCGCTGGA
+AATGAAAGACTGGTGAGTGTAAATTGATACATTTGTAATGAACACCGTCG
+AACAGATGTTTGAATCACTGCTTTAGTTTTTCTATTATAACAGTACACGT
+ATTGTAACAGGTTCTCAAAAGAGTGAATTCTCGTGTTTTTCATACTTAGA
+TAGTCTCTCCATTCCTTCACTTAAAGTTATCCCAAAAACAAACAGCCCAC
+TGCGATCAATGTCATGGAAACTTTATTCTCGTTTTTTTCGTTCTTCTGAG
+AGGAAATCGGAAAATCGAATAATTGGATATTGAAAAACGGAAAATTTCGG
+TGTTTCAATTTTCCGGAAAACCAAAAATCGGATTGTTTAGAAAATTAACA
+AAAAAATCAAATTTTGTTTTTGTTGATGAAAAACTCAGACACTCTTGACA
+TGATATGCTCAGGAACATTATAAAGATTACATTTTACAGGTTGTTTTATC
+GGACCATATACGAAAAGCAACTAGGGCGGTACGTAGTTGGTGCTCGAGCA
+AATTATTTCCTCAATTCATTGGTAACATGCCACACATTCACCGTTTTAAT
+ACTGGGAAAAGAGTTCCTTTCAATCCCAAGAGACTTTTTATACCAGCTTA
+TTTCAAAGTGGAATGTTAAGGATTTCAGACTGGAGTTCCGGTTCGAAGCT
+TACAGTGGTCATTTTAATACTATGTTTAGTTCAAATATGGATTTCATTTT
+GGAAACGTCTAAAGACTTTTCAAATGCCGTATTCAATGTACCATTCAACA
+CCCAACCCGTTTCGAGGGTTCTTCTGGAAAAAGTGGAGATCGATTTACAA
+TACTCTGAGGATATGTTACTCGAAATGAACGAACAACTGGAAAACGACTA
+TTATTCACCAATGGACAATGTGATTGCAAATGTTCAACGAAACTTCCCAG
+CCAAGAGTATGACTGTTCTACTTCCTAAAACGTATCTCCTCATTACTCCG
+GACAATATGGACAGAGTCACAGCAAAGCTAATCCGATTGACTGAACAAAA
+CAGCCAGAGAAATGGAAGTGTCACATTCAACTTATACTATCAGCATGACA
+AAGGAGAAAAACATATTCCAGAGGATATCCCAGACATTTTCAATTCAAGA
+GCACGTCTTGTAGGTGAAAAACCAGTAGATTGTTGGTATCTCGATGATAT
+TTTAAATATCCCCAAAGAAAATTTCAAGGATGGATTTGGAGAAGTGACTG
+TCTGGTATGGAAAAAGCTTTCAAATAAGAAATTCCACAGAAAATCGAAGA
+ATGAATTTTAATATATTCTATACCAAAAGCTATCTGAAAAAGTTCTTCAA
+TGAGAGACATAGTAGATGGGTGAAAACTGGATTTTTATTGCATTTCATGG
+ATCTTATTAATTGATTTTATGTGTATTTCTGTTACTACTAATAAAGCAAA
+TACTCTGTCCGTCCAAACCATGTAGCCTGTAGACCTCGGACAAGAGTTGG
+GCGCTGCCTAAAAAATGAAAAAAGTCGTCAACTACCTCGTCGTCTCGAGG
+CGTCGCCGAAGTCTTACCTGCTGAGCCATGATGGTCGCGCGGAAAGATGC
+ACACTAGTAATAACATATCGTACTCATATTCTGATAGTTTTTTTTGGGGA
+AGTGTCAGACGTATCTGATTGATACGGTATTCTCACATACCTTATTTCAT
+TCGTTTTCAAGTGTGCTCACTAAGGATTCTAATAGTAAGTTCAGAATTTA
+CAGAATTACTGTAATTCAAGTTTGTTTCATGTCTTTCAATAACAGACAAT
+TTTATAAAATTTTGCATTTCAAAGGAACAGTTCAGTCTTAGAAAAATTCA
+AAATTTGATCCATGGGATTGACTGACTATTGTTTGTATACCAGCCGTTCG
+CACAATGCGAGTGCTCCGACTGGCGTACTCGAAATTAAGATGAAATTCTA
+AAATTTCTAAGCCTTGGAACGTTTTTCTCAGTCTTCCAGAAGTTTTTAAA
+GCAACATGAATATTATATAACTAAGTTTTCAAAAGTTACAGATGTTTTCG
+GCCGAAATTAGACTATTTTGCAATATTTTGCGACTTTTTGCTGAAAAATG
+GTACCCATCAGAGATGTGCGGCATGTGCCGAACGGCATGTGCCGATGTGC
+CGAAAATTATTCCACTCGGCACATCGGCATGTGCCGACCTTTTTTGTCGG
+CACATTTCGGCACATTTCGGCATATTCGGCACTGTCTGGAATATGTACCA
+AAATTTATTTTTTAATTTTAAAAATGCAAAGAAACTTCAAAAAATTGATT
+AAAATTTTCGGAATTTATCATTTCAACTTATAGTTTACTAACTTCAATAT
+TAAGACAAATGCACTGCATTTTTTATGGGGTTATCCAACTGAATGTTCCC
+GCTTTTTCCTCCTGTTTCCCCCCTCTAGTCGCGATCCAACTGGGAGGAAA
+AATGCATTTTCCCCTCGTTTTCGCATTTTTTAGCTGCGAAATTTCAGAAC
+TGAGCTTAGGGTGGGCATTTATAGACTTTTTTTAATTTTTTTTGACCAGA
+AAAAGTTAAATTTTTATAGTTATTTTACCAATTGGACCTTAAATTTGAGC
+TATGATATCTTTGTGGTAAGCCAGAGTCATGGTGAGTGATCAACTACAGA
+GTTGTAGCAAATTTTCTGTTTAAAATTTTGTTAGTTGATCAATTCTTGGT
+ATCATAGATTTTCACAGACTAACATAGCTGTGAAACTGGACAATTTCTTA
+ATGTAAATTGCGTACACGAGATTTCTCTATTTTCCGCGTGGAGTACTAAT
+ACCAAAAATTGATCAACTAACAAAATTTTAAACAGAAACCTTGCTACAAC
+TCTGTAGTTGATCACTTACCATGACTGTGGCTCACCACAAAGATATCATA
+GCTCAAAGTTAAGGTCCAATTCATTTTAAAAAAAACTATAAAAATTTAAC
+TATTTCTGGTCAAAGAAAGCTGGAACCGCATTAAAAATTATGTTATTTTA
+GTATTTCAACAAATGTCTAACTGTGAAAATTAAAAGTAAGTTTGAAAAAA
+TTTCTTTAAAACATTTTTTGATAATTTTTTCATGTCCTGTGCAGATTTCA
+AATTTTGAAACAATACTTTTAATTCTCATATATCTCCGTTGAAAAATTTT
+TTATGACAAAGTGATCAATTACAAAGTTGTACTTTGGATTAAGAAAAAAA
+AACTTTGTAGTTGATCACTTTGTCATATAAATTTTTTCCACGGAGATATA
+CGCATCCGAAGTGAATGAGTTTTCACTATCAATTCTACTAAACCCTATGT
+TTTTGTCTGAAATCGTGTTCAGAACATCCAAACTGAAAAAAACAACAAAC
+ATTGCAAGTAATTTTTTGTTATTTATTTAAATTGATGAACTTTTTGTTTT
+TTTTAAGAAGCTATATAGTATCTTTGCAAATGTGCCGAATGTGCCGATTT
+TTTTAGGTTCGGCATGTACCGAGTGCCGAGAAAAAATTAATTCGGCACAT
+CGGCATGTGCCGATGTGCCGAAATTTCAACAAGTGCCGCACATCTCTGGT
+ACCCATCGTCTCGTCACGACAAATTTTTGTTAAATTCGAGTATGTGTGCG
+CCTTTAAAGAGTACTGTAATTTGAAACTTTCGTTCCTATGGAATTTTCTT
+TGACTTTTCACTTTTTCCTCTGGTTTTTATCCAATATTCATAGAAAAAAA
+GAGAAAATTTTTCTAAAAATCGAAAGTTTGAAGTTACAGTACTCCTTAAA
+GGCGCATAACGTTTCGGAATAAACAAAAATTTGTCGTGGCGAGACCTGAG
+TATTATTACAGGAACGCAAAATTCGGAGAATGCGTTTTACACAACATATT
+TGACGCGCAAAATATCTCGTAGCGAAAACTACAGTCATTTTTTAAATGAC
+TACTGTAGCACTGGTGTCGATTTACGGGCTAGATTTTTATTAATTTCTGA
+AAATTGAGCACCCGTAAATCGACACTACTGTAGTTATTTGAACAGGATTA
+CTGTAGTTTTTCGCTACGAGATAATTTGCGCGTCAGATATTTTGTGCAAT
+ACGCATTATAAGGGACAAGTTCTCCAGTGAATTCTTCCAATTACATTGAA
+ATCCTTCTATTTTGAATACAAATTACTCAAAAGACAAAGTGTCGATTTAG
+CCTAAACATTGCGCATGCGTAATTTCTGAATCTTGTTCGTTCTTTACATC
+TGCACACTTGGGTAAGAAGTTGGGCAGCCTATGTTTTAGAGGGAAGTCAA
+CAATGTTATTTTCGCACTTGTGGCAACAGAGTTGAAACTACGGTACTGTA
+TATGGGTACACCTTTTAAAATTTTAAACAAAAATTTGTCTTGTTGAGACC
+GGAGCACATAGATATTCTCAGTGTGTATTTGTCTAAAAACCTGCCAATAT
+TTGAAAATCTTTCAAAACTTCAATATTTTGCTCCAAAAATTAAATTTTTC
+AAATAATCTACAAAAAGAATCCAATTTGACTGAAAACCTGCTAATATTTA
+AAAATCTTTCAAATGTATAATTTTTTTGCTCCAAAAACTGATTTTTTTCA
+AATAATCACAATTTCAATTTTAATTTCGATAAAGATACACAAAAAAAAAG
+AATAGCATTTAAGGATTTCCTTGTTAAGCTTCAACAGCGTAAGGGAAGGC
+CTCGTTGGCAATCATCATGCGTGTAAGTTCGGCGGCGCTGAAAATAAATT
+TTTGATGTTTAGCTTGCATGGTATGTATTACTGATCCCTCAACTCCGCCA
+TGGTCCGACCCTGACGAAGTGGTATCTCTCCAGCATGGTGAACTCTGACG
+TGATTCCAGTGCACAAGCCTTGTTGCAGTATACGACAGCCCACAGATACC
+GCAGTAATACGGATAGGGAAGGGTATGCAGATGGTAGACGTGGCGAGCCC
+TGAATGTTGAAACTGACTTTTTGAAATGACTGGAAAAATAATTACAAGTC
+AACTTGCTGTCCGAAATTCATCATTACAAATGGAGCATTGGAATTGTTGA
+GCATCAGGAGATTCCGAATTCCGATGGGTATCTTGAGGCTCTTCCATTTC
+CTGAAAATTGTAATTTTAGACTTTTTAGATAATATTCACAAAATCTGTTT
+AGGAAAAATTAACTACTAAAGTTACAGTAAGAATTTTGCTCTGAATTTGC
+TCATAAAGGAAATTTTTTTAAGCTTGCACCCTGATTTGTTTAAATTCTTC
+AATCTTTGGATTCCTCGCAAAAAATTCAATTCAGTCTCCTGGGCGTCGAA
+TTGCGATGGAGCGCGCTTGCCGTGCGTTGGCGCAGCCACGGTGGTTCAGT
+TGTAAGATGGGTGCAAACGCGCTCCACAGAGTTTTCGATCCCCAGGAGAC
+TGTGTCCAAGTAAACTGAGTGGTAGCTTTTTTGTTCAAAAAATGTGCCCC
+GCCCATTGGAAAAGCATGACCTTGTAATCGAAAATCCTTCAAATACGATT
+TCTATTCAAATTTACGAAACTGAAAAAAAATTAATTTTACGAACACTTTG
+ACGTCCATTCGGTGAGATTCTTTCAGGTGTGAATCGTTTTCTCTTGTTAC
+GAGCATCATTTGGCTCCGGCACCGCCATCTGACCGGCCTAAAATAAGAAT
+GTTTAAAAAAATATGCATTTAGGAAGTTTAATATTCAAAACAGAAGAGAC
+ACATTCCATATGAAAACAACTTACATTCTGAACGTTTCCAACGTCCGCCG
+ATTCCTTTACACCGTATCGATCGATTAAAAAATCGATCAGCTGACCGTTG
+AGCAGTACATCCTGGAGCGAGATGGTGATCGGAGCCACCGGTGGTGCAGT
+CTCATCGTCTGAAGATCCAGATCCGAAGGCATAGCTGTCCGAGTGGATGG
+TGTTGGAGTGGTCGAATTTCTGAAAATTGACCAATTTTTGATTTTTTAGA
+CTTGAAAAGGCCTAAAAAGGACAAAACGAGCCCCAAAAATTTGAACAAAA
+GGGTTGAAATTTCATATTTTGTTAATTTTTCTGTGTCACAATTTTGATTT
+TCAATCTATCGATATTTTGAATAAATTTCAATTTTTTCGGGAAAATATTG
+CAAAATTTAGTCATTTTTCCTCAAAATAAACCAAAATTTGATTTTAAAAG
+TTTGGAGAATGAATTGTTGAACTTGGAAACACCAAAATTAGCTCTAAAAT
+TTCGAAAAAATGGGTAATTTCAACTTTCCGTATCTTTTCAGTTTGTCGGA
+ATTTTTAAAAAATTTTATTACAGAAAACCACCAATAATTAAAATCTTGAC
+TTTTTTTTTAACCCTAAAAGATTTTTTTCGAGAAAATATCTTAAAATTTA
+GTCATTTTTCTTCTTTTTAGGAGCTATTTTTATGTTTTTTACTTTTTGTT
+CCGTCAAAAACAATTTTAATTGTAAAGGTTTTTTTACGATTTTTCCAGAA
+AAACCGGTAAATGACACTATTACGGGAACAAAAAATTTGGAAAATGCGTA
+CTGCACAACATATCTGACGCACAAAATATCTTGTAGCGAAAACTACAGTA
+ATCCTTTTCAAATGGCTACTGTAGTGTCGAATTACGGGGCTCGATGTTCA
+GAAATTAATTTTTTAATCGAGCCCCGTAAATCGACACTACAGTAGCCATT
+TGAAAAGTATTACTGTAGTTTTCGCTACGAGACCCTATTTTGCGCGTCGA
+ATATGTTGTACAGTACGCATTTTCAGAATTTTGTGTTCCTGTAATAATAC
+TAAGATCTCGCCACGACAAAGCGAAAAATTTTTATCGATTTTTCAGCAAT
+TTTTCTCTTGTTTTCATAAAAATTGGGCAAAAACCGGAGGAAAAAAGTGA
+CGAATTAATAAAAATTCCATGGCAACGAAAGTTTGAAGCTACAGTACTCT
+TTAAAGAAGTGCACCTTTTTGGATTAACAAAATTTTGTCGTGACGAGACC
+CTGGATACCATTTTTCCGGCGGAAAAGTCGCAAAATTAGCGATTTTGGGA
+ATTTTTCGCGGCGAGACAACTGCACAACTCGACATGCGAGTTTATCCTTG
+CAGATGGCCAAAAGCCCTCCGTCGATCATTTGACGAAGCAATTCCCTGGT
+GTTGCGAGCTCGACGAGCTTCTGAACGATGAAATTGCCATTTCGACTGTG
+GCAGAGCCCCACGAAGAGCGTCGTGGATTTGGTGAGCTTCTCGAACACGG
+CTTTACGAATCTGATCTTCGGAATTTAGTGGATAGTTGGCCTCCAAGAAC
+CTTACCCCCGATGGATAGATTGCGAAATCGATGAGCTGCCCGTTGAGCAG
+CACATCTTCGAGCGAAATGAAAATCGGAGCCACTGGTGGTGGGGTCTCAT
+CGTCGGATGATCCCGATCCACTGTTGAGGATAAAGCTGTCCGAGTCGGAG
+GAGGTGGTGTTGCTTCCGTGGCGGTAGGGGAGAAGCTTGACCGGCGGCTT
+TGGATTCTGGAAATTCGAATTTTAAACTTTTATTATATTTTTATTTAAAT
+TAGAAATTTTTATGCAATATTTTACCTTGTTCTTGTGAGTTTTTTTCGAC
+AAAAGCGAGAAATCCGGGTCGAAATCGAACGACGCGCCGAGCATGTTGTA
+CGAATCCGTGCTTTTACGATTCGGAGTCATTTAGACAGAAAAATGAATGA
+ATATAGGTTAGTAGACGCTGAAAAATTGGGAATTTTGGATTTTTTAACGG
+AAAAACGAGTGAAAATGAGAGAAAAACATGTAAATTTCAACGAAAATCGC
+GAAATTACCGCGCATCGAAATTCAAAATTGAATTTTTCGCGGTGGCCCGG
+GTTACGGTGATTTTTAAAGGCGCATGGTTGTTTTGAGTGAGGTATTGACG
+CGAAATTTAAAATTATTGAATATTTTTTTCTTATTTTTACATTTTTGAAG
+AAAAAAATGATTAAAATTCGATTTTTTAGGGAAAATTAAACATTTTCACA
+AAAATTGCAGGAAATCACTCGCCAAAATTCAAAAATGAAGAGTTTCGTGG
+TGCGCCGGGTTACGGTGGATTTTAAAGGCGCATGGCTGTTTTGTATTAGG
+TCTCACCACGAAACTTGGAGTTTTTGATAGTTTACTTCCTATTAGGGATT
+TATTTTTTTAATTTTCGCTCGATTTTCACACATTTTCACTCATATTCACT
+CAATTTTTTGCAGAAAAAATGTCAATGGACATTGTTATGAAGTCAGATGA
+GCAGCCGTTCATCTCTGCGCCTGTATGCTTTAAGTAAGCTCCAATTTTTG
+TTATTCTGGCCTAAAATTATTTTTTTGATTTCCAGAACGTTCGCATTTTT
+CGCCAAAGCATCCGCAGAGGAATGCAAACTTCTAGCTTCGGGCTCCAACG
+CTCGAGAAAGTTTCCAGCAGGCCACGGGGCTATCGGAGAAGATCACGGAA
+GACATTTACCGCCAAATTGAGTAGGTTTTTCGATTTTTTTACCCTTAAAA
+ACTACTATTTTTCTATTTTCCAGCGTCTCCCACATTTCATCGATGGTCTT
+CAACAGAGAAATGGACGGTGGCATCGAGAGAAATCGGCTCGGCTCGCAAG
+CGATTCTGCTCGACGAGAACTCCAGGCGCCGCAATCCACAGTTCAAATCG
+ATCGCGCTCCGCTCTCTCCGCTACGATCACATCGATCATAGAGCGTTGGC
+AAGGAAATCGCCTCATCTGATGCCTCCGACTTATATCAAAGAGGAAATTA
+TGGATGATGAGCTCGACGAGGTGAAGGAAGAAGTGGTTTCCGTTGGAGAA
+GCCGCCTTGCCCACGCCAAAAGTTGAACTGAACATGGACCATCCGGAAAA
+GGACCTGATCATCAGCATTTCCGTGTATCTCGGCTACACCCGTACCCTTC
+AATACCACGAGATTCGTCTCGGACGTTTGATGAAGGTCACGGATCGGCTC
+GAGCTCACCGGAGATCACACGCTTCGCGATCTGAAAAACGCGTTCTCGTG
+CCCCATCGATTTCTCGTTTTCCGACGATTTTAGCGAGAAAAAGCCGTCGT
+TCAAGGATATGGCGAAAAATAAGTGGCCGTCGTCGATGTTCTTCATTCAT
+GACACGTTTTATATCGACTCGAACACTGGCGACAAGTTTGTGGATCCGTC
+GATGTGAGCAAGGGTGCCGGCTAAAAGTTTTTCAGTGTTTTTTGAGCGAA
+AAGGAACAATTTTTTTCTGAAAATTATTGATTTTTCGTTAGTCTTCAGAA
+AAAATGATTTTTTACGCCGCAAAATCGGGAAAAAACAAAAGAAAACTGAA
+AATTAAGACATTTTCGTTGATAAAAACGAATTTTTTGGTTTTTTTTTTCA
+GAAATATATTATTTTTTGCTTTATTTCAACAAAAAAAACCCAAATTTTCA
+GCACAATCCGAAGTTGGGCCAAAAAGTTCGACTACATCGGTCCGATGCAC
+GTGAAACAGATGTCGGAGACGAGGATCGGGGATCTCATTTGTCGGCTCGG
+TCAGCCATACGTCTACATTCATCAAGGCGTCTGCGAGCACCTCATCGTCT
+TCAATGACTTGTGCCTGAGGTACGGAAATTCTGGAAAAATCGAAAATTTT
+GATTTAAAAAAACTCAAATATTTATGTGTTCTTTTTTTTACTAAAAATTT
+TTTTCAAATTGTTTATGAAAAAAACACTAAAAAATAAGTTTTTATCAATT
+ATTTAAACAAAATTTATATTTTCCGATTATCAAAATTGTTTTTTTTTTTC
+AAATAAAATACCCCGAAAAATATATATTTTTTAATTTTTTTTTTCTATTT
+TTTGCAGAGATGAATCCCACACAAACGTCGAATTTCCACGCCGCCTCGTC
+GAACGGAATTTCAGAAGAATTGCATGTGACACGTGCAAGGAGGCGTCGGC
+GCAGTGAGTAGTAGCATTTAGAAATTCGGAATTTTTTGTGAAACCCCCGA
+AAAATATAGTTTTTATCGGAGTTCGAATTTTCGAAAAAAAAATCCAAAGA
+GAATCGATTAAGGCAAAAATCATCAATTGAATCCAATTTTTTCAGCTGGA
+TGATCGTCGACCACGACAATCTGCTTCCCAACTCGCCAGGCTATCTGTGC
+TCTTCGTGCTACAAGGAGTTCTGTTTCGACGTGAACGGCAAAAAAGTGTG
+CCAGTTTAAGGCCGTACCGTATTGCGATCGAAAGGACATTGGCGACGGAC
+GCCAGTTCTTCACCGAGCTCGATCTTTAGAGAACGAGATTTAAAAGTCTG
+TATCATTTTTTGTTGTTTTTTTTTAAATGTTTTTCGATTTGATTGTTTAA
+TTACCGATTTTTGGCCTGTAACTATATTTGTTGAAATTTCAAATTTCTTT
+TTTTTTAAATAAAATTTTTGTTTGCAAAAAAATTTATCCAATAAATAAAC
+GGAATATATCGATGATATGGCAAGTAGGGGGAAACGGACGGGAAAATGAT
+TATTTACAGAAAGGGCGCGCACCAGAGGTTTCTCGGGGGAGCCCCGAGGC
+GGGTGGCGGAGCTTGGCTCAAAATCTGTCGGAAAAATGGGTTAAATGAGA
+GAAGAGGTAACCTAGAAAATGAGATGAGAAATTCGGAAGAATTTTGAACA
+ATTTGAAAAATCGATAATGTTGAATTTTAAAATTAAATTTTATTGATTTT
+TTGAAAATCGATTATATTGTTGATTATTGATTAAAAATCACTAGAATCAA
+TAAATCTGATTTGGAAAAATCAAAAAAATCGATTTTTTATAATCATAAAA
+ATCAATTTTTAAAATCCAAAAAAATCGATATTTAAGAAATTGAAAAAAAA
+TCGATAAATCAATACATAGGTGAGCTCGTCTCGTCGATTTGTGTTTTTGT
+GATTGGTCCCGGCTGCTTTTGAGATGGTCTAGGCGTTGTTCCGTATGACA
+TTCTGGAAATTTTTTTGTGAGGCAATGACACGCCCACAAAATGGACGGTG
+GCAGAAATTTAATAATTTTAAATAATTTTCTGGATAAAAAAATCGATTTT
+TCCACTTTTTCGAGTGAATCGAAAATTTAAAAAAAACATTCAAAATTGTT
+CAGGGTCTCGCCACGAAAAACTCACAAATGCACGTTATGCGGAGCGTCGT
+CGGATTCCGGTGTGTTGCTACGGATCGTGTCGTCCATGCTCAGCTTCATC
+GTCGATTGACGTCGCCGTTTTGTGGTGATCTGAGCGAGATTTATTGATTT
+TTAAAGACGCATGGCCTAGAAAACACAACACTTCGGCCACGGACTTTGGC
+GGCCGAGTTTTCTAGGCCATGCTGCGGCATTTAAAGGCACATACCATGAT
+AATGAAGATCGCCAATCCGAAAATGATGACCAATGCGAAAGTGATGATTA
+CAATCATCAGCGATGATAAGGAATATGATGAAGTTTGCGTGGAAATAGAA
+TCGATGTACGCTTGTGACGTCATTCCTGGAAATTATTGATTTTTTTGGAA
+AAAATCAATAATTACTTACCGTCAACAGTAACACTCAACGAATCAATCTT
+GTAATCCGAAATCATAGAGTTATTGCGTGAAAATGCGGCTTCGAACCTGA
+AATGTTAAAAAAATCAATTATCGATTTTTTTGAAAGTTTTTGAAAGTTTT
+TGAAAAATTGATACAATTAACTTGATATTCCCCCGGAAAACCTATAAATC
+AATGAAAAAGTTAATATCTAAATTTTTTCCAAAAATTGAACTAAAGTCGA
+TTATCGATTATCGATTTTACTAATCATTTTTCAAAAATCTATCATATAGA
+CGATTCCTACGGAAACCCCGAACAAATCAAAAATCGATAAAATTGACTAT
+CGATATTTTTTTCTAAATTTTACTTTTTTCGATAAAAGTCGATAGCGTTG
+ATAATCGATTTTTTAGAGTTTTCCTCAAAAAATGGTAATAAAATATTTCT
+AATCGGTAAGAACTCACAAATTAACAGCCATTTGAGCATCACCAAGTGAT
+TTTTTGGTGAGCACGTCGGCTCCGACAACCACTGATCCTTTGGTCAGTGA
+CTTGATTTCAACATTCACAAAATTGTCGTCTCCCGAAATGGAATTGATGA
+ATTCTCCGATCTGGAAAAAAATCAATAATTGTTTAAAATTGATTTTTTTC
+AGATCATTTTTAAAATAACTAGTCTAAATCTATATTGAAGTCTAACTCAA
+AATTTTCCACAAAGGCTTACTATTAGGCTTAGGCTTAGGCTTAGGCTTAA
+GCTCAGGCTTAGGCTTAGGCCACGCGAGATGAAAACAAAAGAGAAAATTT
+AGTGAAAACAAGAAAAATTTCTTTTAAAAAAAAGAAAAAAAAAAAAAAAA
+AAGAGCAACAGCCATGCAATTCTTAAATATAACAGGTTCAACTACTATCT
+TCAAAAATCAGTTTAATATCGATTTTTCCCAAATGTCAATAATCCATTAT
+CCATTTTTGACTCACCGCTGGCACCAAATCTTTCGCTAATCTCTTCGCAG
+GGCCACTCTGAATATCGTTGAATTCCTCTACAAATTCCAGTGAAATAATA
+CGAAAAACTATTGGTGTTCGAATGGATTTAGCCGGAAGGAATACTTTCGA
+TGAGTTTTGAAGTGCCACCGGCACAGTTGAAATATCTTCAAAAGTCGTGG
+ATTCCTCTGATGAGGTGGAGGTGGTCTCTTCGGAGGAGGTAGTGACGTCA
+GTGGAGAGGGTTGATGGCTCGGTTTCGGCCATGGTTGTGTCCATTGTGGT
+TTCCATAGTTTTTGTAGTTTCCATTGTTGAAGAGGATTTCATTCTGAAAA
+TTTTGAAGTTTTGAATTTTTTCCTGCAATATATGAACACTTCCGAACCAG
+CAAAACTCACTAGGTAGTGTTTTAACTATACGGTGCGATCGAGTAAAAGT
+GTCATGCGATAGCTGGCATCTTAGGCTTTCAGAATCTGTAATTTGTTCCG
+GCGGAAGACCTCTGTGAGTCTGGAAATTTTCATCTGAAAATTTAGTACTG
+AAATCTGCATTTCCTATGGTTAACAGTGGATTTTTGTCTCTGGCGCCAAC
+AGAAGTCTCACCACAATGGTGGAAGGGCGAAAACATCGCTTCGAAGCTGT
+TAACCATAGGAAATGCACTGATTTCAGTACTAAATTTTCAGATGAAAATT
+TCCAGACTCACAGAGGTCTTCCGCCGGAACAAATTACAGATTCTGAAAGC
+CTAAGATGCCAGCTATCGCATGACACGTTTACTTTTACTCGATCGCACCG
+TATAGTTAAAACACTCCCTAGTCAGATATGTGCTCTACACTTTTAAATTT
+TGCAATCAAAATACTTGAATATAAAATTAAGAGATTTTTGAATTTACTAG
+GCCACCTCGAAAATTTCTAGGCCACGGCAGGTTGGTAGGGTGAAGCTGCA
+GACCCCATAAAGCTGTGAGAACGGTTTTTTTGCAAATTTTTTAAAACAAA
+CATTTGTGAAGAATCTGAATATTATCAGAACAAAAAATAATTTCGACAAA
+AAATAATAAATTTTTTTATCAATATTCAAAATTTTTAACTTCCGAAAAAA
+CTCAAAAAAAAACTCACCCAGTCGTAGTGCTCTCGACCATCTGCTTCGTA
+GTTTTCGGGATATTCGACAAAATCTTTGGCTCTTCCTCAGACATTTTCAG
+AATTGGGAATGCGGGGCTCTGATCTGTGCTCAATGAGCTATCAATAACAC
+TTCCATCCTGCTCAAAAAGTCCTTCCAGTGCACTTTGATCAAATGGTGTT
+TCTCCGTCATCTCCAGCTTCTGATGGGTCACTTACTGCGACGGTGGATTG
+GGTTGTGGTCACTGTAAAATTGGAAATTTGGAAGAGAAAAACCTCGGCCA
+TTGGTGACGTCATACTTTTCGCCACTTCTTCGACCAGCTATAATGCCACG
+CTTTTAGCAAGTTTTATTTTTGGTAAACCAAAGAGCAACCAATTTTAAAA
+CTGTGTCTCCAGGTTTACCGCCAACTTAAGGGCGTGTCCGTACAGGGTTT
+GCCCGTTTTATGGGCGTCGCTTAATAAATCATTTTTCAAGTTTTCAGTTT
+CGTGGAAAATTAGCATCCGGGAAATTGAGTCATAAGTATGACGTCAGCAG
+CCGCGCGGCTTCCCATGACGTCACTCCATGCGCTCCCCCGACGTCCCTCT
+AAGACGTCACCACCTCTCACCTGGTTTAGTGGGTCGTGTCATCTCCTTCT
+CTTTCAAAACTCGTCTATCAGCGACCTCGTCAACCTCAATCGGAAGGGAG
+CTGAACGTAATCACCTCCAAGGGAGTGGTTGGCATCATTTCAGTCGTATT
+TTCAGCGGCGAGAGTTGTTTTCTCAGTGGATTCATCCTGATCCTCCATAC
+TATCATCTTCGATTGTTGCCTGGGAGAAGTTGAACATACCGCCGTCAAGC
+GGAGTTATTGGGGAGAAGACGGACGTTTTCTGGATTGGGTTCACTTCTAG
+GGAGGTGTCGTTCGGCGAGAGTTCGATCATTTCTGTACTTGTCTCGAAGG
+TATCTGATCTGAAAGTTATGACATTTTTTTGGTGGTGGCCTGGGAGAAAA
+CTAGGCCTCCTGGCCTAGAAATCTCAAACCTCGGCCTCCAGCTCTCACTA
+GCTGACCTAGGTTTACTAAACATCGGCAAGACCTCTTTTCGACTACTCCC
+TTACAAATTTTTAACAGTTTTTCATCACACAATTTTCCGATTCTTACCCC
+TCATTCATCATTTCTTCTTTCGGAACAGCCATCATCGGCATATCATCATT
+ATCAGGCATTACGGGTGTCGTTGTGTCTTTTGCCAGCGGTTTGTCGAACA
+CATCTTCAGAATTTTCGTCTTGCGCGAAGGAAACTGAAAAAGTTAAATTA
+CATTTTTTCTAGGCCACCAGGTTTTGCATTTTGGCCTAGAAAATGAAATG
+AGAAGCTAGACCATGTGGGTTTATTGCGAGGAAAAGCTATCCCACGAAAA
+CTTTTATAAGCGTCTAGAAAAGTAGAAACCTCGGCCACCAAGTTTTGCAC
+TGTGACCTAAACAATTTTGGTAAAATAGGCCAGCAAAATTTCCATGATGG
+CCTCAGGAAAACTAGGCCATTAAGGTTTCTTCCGTTACCTAGAAATTTTG
+TAAACCTAGGTCACCAGGGTTTCTAGGCCACACAAGAAAAGCTAAAAACC
+AACATTTCAGATCGGTCTGGAAAAGTGCAAAATTAAGCCACCAGGATTTG
+CATGGTGGTAAAAAATTGGTAAACGTGAACTAGAAGTTTATCGGTCATCA
+ACTTACGTGTCGTTGAAAATGCAATGAATAGAATAAAACCAAATGGTATG
+CGCATCGCTGAAAAATTGCAAAAATTAATTTATGTTTTGGAAAATCAGAA
+ATCGGAGTGTTCATTTTTTATGGGACAAGATAAAAAGAGATGGAGAAAAT
+TTATATGATATATCAGGTCAAAATGACCTTCGGAAATTGGGAATGAAAAA
+TCAAAATTAATTCGCGTGGAACTGGTTAAGATGATCGAAGATTGAAAAAT
+TTGACAGAAATTGCAACAATACTAATGCAAAAAGTTGGTAAAATATTTTT
+TTCAGTTTTCAGAAAAATCGATAGCAAAAGTCTTTTTTTTTAAATAAAAA
+TTTCTGAAATATTTTCGCTGCGAGACCTAAGGTGACAAATTGGATTAAAA
+ATTTTATGTGCCCATTAAGAGTTTTTCTGGAAACTGAAGAGAAAGTCGAA
+AAATTAATATACCCTACTTAAATTTAAAGGCGCACGGATGAATTTCCAGA
+AAACTAAAAAAAAACATCACAAAATTTGATACTCCAAGTTTAAAGATGCA
+TGGGTAATCTTTGAATGAGAATTTTGTTTTAAATTTTTGAACTGCCATTT
+CAGATATTATGAGAACACAAAATTCTAATAATGCGTATTGCGCAACATAT
+TTTGCGCTCAAAATATCTCGTAGCGAAAACTACAGTAATTCTTTAAATAA
+CTACTGTAACGCTTGTGTCGATTTACGCGCATCAAAATGAATTAAGATCA
+TACATTTACCGACAAAATATTAAAATTAGGCAAAAAATAATACGAATAAT
+GCATTTCGTAAATCGAGCACGTAAATCGACACAAGCGCTACAGTAGTCAT
+CAAGAAAAATTACTGTACTTCTCGTTACGAGATATTTTGCGCATAAAATA
+TGCTGCGCATTACGCATTCTCAGAATTTTGTGCGCCCGTAATAACCATTT
+GTTAAATGCTTAAAAAATTCAGATTTTATTGAAAAAAATTTTTGAGCAAA
+ATTTTTCGAAAAATAAATTTCGGCAATAAAATATTATTTTTCCATCGAAA
+AAGTATCGTATGGTGTGCTTGACATAATCTTGGTAAAAAGTGGCATATTT
+TGAAAACAAAAGGGGTTACCCCCTTCCTTCAGCCCGCCCGCCCGGGAAGC
+CTGGGCATGCGCGCAAGTGATTGTTTTGTCTGTTGTTGCTTATGTATATG
+CTTATTATTTACACATTTGTGTGTGTGTGAGTGACTACACTGCACACCTC
+TTGAAACGGATTATCCGGCCGTGGTCGAGGAGGGCCGCCGAATTATGCAC
+ATTCCTATGCTATGTATTGTGAATACTTCATTTCAATAACTTTATATATA
+TACAGTTAGCACATACGATTTTTGAAAATTGGGGTTGTGGAAGAGTTTTC
+ACACAAGTGGCCTAAAGTTTTTGAGTTTACTTTAATACTTCTAAATCACG
+TGGTGTCAGGCGGTCTCAATACAATTTGATCTACAAAAAATGCCGGCATT
+TTTTCCCAGAAAAATTGTGACGTCCGCACGCTCTCAACCATAAAAAATCA
+GATGAGATCTGCGTCTCAACTCCCGCATTTTTTGAAGATCAAAGCGAAAT
+GGGACTTTCTGACTCCACGTGCTAAATGAAATGTACGTTAAAAAATTATC
+TCTGGAAATTTGGAATTGCTCGGTGGAGCGCGTTTGCCGCTTAGTAGCTG
+AACCGTGATAGCTGCGCCGTGAAGAGAAGGGAAAAGTAAGGAAGTTATCA
+AAACCAACGACGCACTAATGAAAAGGAACACAAGAAAAAGTGAAAGTGTT
+TTTTTTTGGGTTTTTGTGATTTAGTTCGTGTGTGATAAAAGTTCAAATGG
+TTCGGCAGGACAATAGGAAGGAAACTGGAATTTTATATTTCATCTCTTGT
+TAAATTTACTTTTGTAGGTGTATGATTAGGTAGTGTTAATAGAAATCGGG
+ACTCGTGGCCTATCATTTTTTTGTGGCCGAGTAAAAAAATCTTCCACATT
+CGTCAACCATACGTGTGAATTTAAAGGTAATCTATAGGATATGATATTGG
+TAAACTTTCACAGAAATCCTAAAGCTAGGTTTTGAACTATGGAGCTTTGA
+AGTTTCTAGGCCCCTTTGGGAAACATAGGCCACCAACCTGAGAAAGGTAA
+GGGGAGGGCAGGGTACATAAAATACAACTTTTTCTCTGAAGTTTTTTTTA
+ATTAAGCGAAAAAGCCGACATAAATGTTTCAGTCATGGCCTAACTTGACA
+TTGGTGGCCGATTTTTTCGAAAAACTCTTCCACGATTTAGAACATGAACT
+TGGCAAAACTTCAAACAAATCCTAGAGATAGTTTTTGAATTATGAAGCTT
+TGAAACTTCTAGACACGTTGAAAAAGTTAGACCTCTTCCACTGTCATAAA
+CTTATAAATTCACAATTCAAAAATTATAGATTTCTTTCATATGTAGAATT
+AGCCCAATTTTTAAATCCATTGCACGGCTAGATTTGAAATCATAGCAATT
+TGAAAATTCTAGGCCACGCAAAAGAAAATTCTAGTTCATGGGAGTTGAAA
+GAGAGTCTCGGAAGCTAATTTTAAAAGCACAAGATAGAGGAAAACCAAAA
+ATTTATAAATTCATAAAAATCCAGTTTTTTAGCAGCTATGTGAAAAGGAT
+TAGAATTTCAACACGGCCACCACCGCCGGAGATACAATCATTTTGGGAAT
+ATATGTCGTTTTCGCGTATTTCTCACCAAAAAAAGATTCAAATCTTTTAA
+TACGAAAAAAAGTTGGAAAAGAATTAGAAAAATGCTGAGAAATTTTTTTT
+ATGAAAGCTTAGGCTTACAATTAGGCTTAGGCTTAGGCTTAGTTATTTTT
+TCAGTGTTTTCCAAGTGCAGAAAGGAAGAAACCGACGCTTCCTGACTTTC
+TATCACACACTGAGGGGAATTTCACCCAACCCCCCCCCCCCCCTCACTTC
+CCGCTACTACTTTTACTGTACACTTTCACCGAAAAGTTATTGTGTCATCA
+CGTCATTCGCCAAAAACGAATCGAACAAGGAGAAAAAATTGATGAGAAAA
+CGCAAGTGTTTCTTCCTACACTACATAGTGTTCAACACCCCTTCATGATA
+TGGCCGCGTGAAAACTCTTCCACGACCATAAAAGAAATTTACGGAACAAT
+CTAGCAAATTTTCATAAAAATCGGTTGGAAACTATAAAAGTTACAGGGGT
+TTGAATTTTCTAGGTCATGCGGAAAAAAACTCGGCCACGCAGGTTTTTAG
+GGTTAGGGAGGCGGTGTCTTCAAAAAAAAAGAAACCTCGCACCTAATGAT
+CCATGAATCTTCAAACAGAAAATGAGGTATAATCTTAGGTGGCCGAACTT
+TTGTTTCTGAAGAAAACTCGGCCAAGACCACGAAAAACGTATTTTTTTGT
+ATCGTTAATTGAAAAACTGAAAACAAGAAGTTTCTAGGCCATGTTGATAA
+ACCTTCAGTAAAAATTTTTCCTAAGCCATTAAATTACTACTGAACTGAAA
+ACCTAGGCCACGGCTTCAAAACATAGGCCACCAAAAACTGAAAGGGGGTC
+GTAGGACCGGAACCTGCTATTATGAAGCAAAGTTTTGTGCAATAAAAGTT
+TCAGAATTTCCAAGTTTTTAAACTATTTTTTGTCTGGAAATTATAAACCT
+GAAATTTCGGGTGCGAGACAAGATGGTCAAAGAAAAATAACGAGAATTCG
+GAGGGCAAAAAAATGAGAAGAATTTCCAGGAAAACAAGTGAAAGTGAGTA
+TGACTTTGACCTATACGCGTATTGTCTTTTTTGTTTTCTTCTTCTCGAGA
+AAAGAGAAACTGTCACAGCAGTAGTAGTTCTTCGATCACCTAATTACCTT
+ATTGCCCCCTTCCAGGAAGTCACAGTTTTTTTTAGGAAATGTGTGAAAAA
+TACACATTCCGCTAGGAAAAATTGAAATTGCGGTTATTGAGTTCCCTTGC
+CACGACAACGTGGCCTAGGATACCGCCATGCTCTAGAAATCCCGCTTGTA
+GCCTAGAATTTCCCATTGTGGCCTGGAGAAGTTTAGCGGGGCCTAAGACT
+TTTAATTGTGATCTGAGAGTTTTTTCACATGGCCTAAAATGCTATACGTG
+GTCTAAAATTCCTCATTGTTGAAATTTTTAGCGCGGCTTAGGATTTTCTA
+TTATGGCACTGGATTCTCGCCGTGACCTAGAATTTCGTAATGTGGCCTGA
+AAAGTTTAAGCGTGAAAAGTTTAAGTATTTTCAATCATAGCCTGGAGATT
+TTTTACAAGAATTCCTCATTGTGGCCTTGAATTTTCTATTATGGCCTAGA
+ATTTCGCATCGTGGCCTAGAAGAAATTTGCAGAGTGGTTTTGAAATTCGG
+TTTGTGACCTAGGGTGCTATATTGTGGCCTAAATTCTTCCATCATAACGT
+ATGATTTCACATTTTGACCTGAAAATTCTTTGCGTGGTCTAAGATTTCTC
+ATTATATTCTCGAATTTAACTTCGACACGTGAGAACAATTTTGATGGCCT
+AGAAATTGCTCCCGTGACCTAGGAAGTTTCAAATTTTTAAAGTTCAAATA
+AATTTCACCAGAAATTCATCAAAATTTACAATTACGGAAAAAGAATCATA
+TTAACCACTGCAACTTTTTTCGAACGAAGGACGAGGCAAAAAGGTTTCTA
+GGCCATGGCCGAGTCCCCGACAAATTTCAGCGGCCATTTATTTTGCTTTG
+TTTTTTGCGTGTTTTCTTTCGTTTTTCACCGATTTTTTCCGTTTTTTCTT
+ATCAAAACTAATAAATAAATATTTTTTGCAGATGCTAAAACAATTTCCAA
+GTGAAAAAATTGTGAATTCAGTCGGCAAGTAGCGGTAAAAGTGGTCAATG
+TAATATGATGGATTACGGGAATAAAAAACCCAAACTTTTTCCCAAACATG
+ATACATATGCTGTTTAGAAACACGGGAAAAATCGGTGAAAAACACAAGAA
+AACAAAGCAAGTACAAAATGTCGTAAAATGCGGTGTATTGTGTGCAAACA
+CCGATTTTTCGCATTTTTTCTCGGCCCTCGTTCGAAAAAAGTTGCAGTGT
+TAACGGCGGTGGAAGAGCTTTACCTTTACAAAAGGTGGCCACAAAAAAAA
+TAGAAGAAAGGATCCAAAAAGAGCAGGGAAGAGTTTTCTCAATTTGACGG
+CCACGTGTTCTATAGAAAAAGATAAATACAATAAATACGTTTTTTGAACA
+ATTAAAAAAACAAAAAATTTCAAGAAAAATTTAGAATATTTTTTCAGTTT
+TTTTCCTGAAATTCAAATAGAATAAATGGAAGTTCAACAAAAAAAGGTGA
+CCTAAATACTTATTAATTCACCTTCTTGACCTCTCGATTCTTCAGAAAAA
+AGAATAGGCTTCTCCTCCTCCCACCTCCCAGACACTTATCTACACTTTAC
+ATCATTCCTCCCGGCCCCCGGTTTTTTCACATTTTTCAACCTTGAAAATG
+ACGAAATAAACAAGTGTTTTAGATAAATGTTTCTGTGTATGTTATCTGAA
+ATCTTGGAAGGGTGTTGCAACAGAGCCCCGCGTGTAGCGTGGCCTAGAAA
+TCCAAAAAGTCTTCTTTTAGATCTTCAGCTTTCTCAGCAAGTTAGGTCTT
+AAGTCAAAAGGACTCTCCATGACCAAGTTATAACGATTTGTAGTTTCTAG
+GCCATGGAGTACTCTCCGAAGGGGAGACATTGACCCCCTGACGCCGGATT
+TGTAGGAATTTTCACGTGTTTATGCTACTGTAAGCGAGCTATATACGTTC
+TTCAAAAATATCCGTCAAATTGTGACCACCGTTTCAGCACTTTAAAATTT
+CTAGGCCACGCTGTCGCCATAATGGAATATTTTTCTCACGAGGAATAGAA
+ATTAAAAAAAAAACTCTTCAACTGGTCGATATTTGGAAAACCAAACTAAA
+ATGTTTCAGAATTATTAAAAGCTTAATTAAAACAAACAGCCACAAAAGTT
+ACCTAAACTGATGAAATAAAGACATAGGCATACAGATTTATAAATCCTAT
+AAGCATGGGTGTGTCACAGGTAAAGATTATGGAAAGTGAGGGAAAGTAGG
+AAGATATTACTGGAAAGTTCTGGGGGAGAACGGCTGAAATCAAAATGGAT
+TCGGTTGAACGCGTCGAATCACGGAGACTCGTTTGTAGGGCTTCCAGGTA
+GATAAAAAATGTTCTGCCTGAATTGGGCCAAAACACATGAATCTTCAAAA
+ACAAATTGACACAAGAAAATACATACTACTCCAAATTTTCAAAAATCAAA
+AAATAGGCGATAGGTTTTTAGATACTAAAGTATATTGAGCAATTAAACAA
+TTCACCCCCTACAACTGGCGGGCCCGCAGGGCCTGCTAGTCAGGCAAAAA
+ATATATGGCCCACACTCCCAGCGACAAGAAAAATTAGGGGATATTAGAGA
+CATTTACTCAAAAGGAGCATTACACAAATTTTAAAAATCTCAAAGCGGGA
+AATTTTTTTAATGCGTACTGAATAAGAAATCGACGTTTAATGAAACTCAA
+TTGCTACAACCCCGTAAACCTCCTTCACGTCCAATCAATAGTGACATGAA
+TCCTTCCGACCAACGTCATAAAGATTGGAGATGACGAAATTTAAGATGTA
+CCAAGTATGCTGGTACATACAATTTCTACGTCACAACATCTTGACAGTTT
+TTTCCCTCAAAGAGAGGTGAGCCTGTAGAAGAGATACAAACGCTGCGTCC
+TATCGTGGGTTCAGTTGTGGGGAAAAATTGTAAAAACTGTATGTACCAAC
+TATGCTGATGTGCCAACTACCAACCAGCATAGTTGGTGCATCTTCAATTT
+TGCCATCTCCAATCTTTATGACGTTGGTCGGAAGGACTTTTGTCACTATT
+GATTGGAGGCTTACGGGGTTGAAACAATCGTTCATTAAAAGTCGTATTCT
+TATTCAGTACGCATTTCAAAATGTTTCCCACTTTTTTTCGGCTTGATCTA
+CGTAGATCTTTAAAAAATGCGGGAGAAGATATGCAGTGTTCTCAACTAAT
+TTCGCATAGTTAAGAACGTGCTGACGTCACTTTTTTTTTGAGCAAAACAT
+TCCGGCATTTTTTGTAGATCAATCCGTAATTGGACAGCCTGGCACCACGT
+GTAAGAACACGATGCCTCTATTTTTGCCCGGGAGTGTGGGCCTTGAAAAG
+TTGTGAGCTGTAGAAAAATGGACAACAAGCATGTTGTCAGTTAGCAGCAT
+TTTATAAGTCAAGGACAAGTACAACCGAGATAAGTGAAAAGTTTGAAAAA
+TGGAAAACTTTCAAAAAACAGCGAAGGTTCTTTGATCGATGCAAGGGCAG
+AAAGTGAATAATGCATGTTTTTGAACTTAAAACAAATTGGCTAGACTTTG
+ACTGAAACTACCTTTTATAAAAATGAAGAAAATGAACCATTACGAAAATG
+TTAAATACACCTGAAAATTGGTGTGTTTTTATTGTCGTTCTGTAATTAAA
+TTTTGAATGATCGCTCTTCTGCAAAGAACAACCACAAAAAATAATTCGAT
+ATACTCAAGTATCGACACTTATGATTTGAATGCAAACATATAACAAATTA
+AAATTAAAATACGGTCATTATATTTTAGGAAAATTATGGAAATTTTTTAG
+GCTTATGATGTTTCAAAAACTTTCAGAACTCTAGTAAAAAACATTTTATA
+TGTAATAAAACACTCAGCGACTTTAAACTTTGCAAGACAATTTGGGACAT
+AATTTTGGGACATTGTAAGAACAGTTAATTGGAAAATAAAATAGTTATTC
+GAATGATCGTTCTTCAAACAACCTTACAAACAACAACACACCTACTCTGC
+TATAATAAGAAAATTTAAAATACTACTCAAGTTGTCACTTCAAGACCGCA
+TAAGTTTATACCACTCGAACAAAAAACAGTCTTCGTTCTTTCTTTCTTGA
+AAAGAGACATAATTGAAAATGAACTAATCAGCCGCTGCCCGGGATGGAAA
+AAAGAAAAGAAATTCCTATCATCTTTTGACCTTGTTATTTTTGCAAATCA
+TGTCTGAATAATACACTTTTTGATACATATAAATCAGGCGTGGGCGACAA
+ACAATTTTTCCGGCAAATCGGCAAATTGCTGGAATTGAAATTTCCGGCAA
+ATCGGCAAATCAAAAATGTTTGAAAATAGGAGAGTAAAAAGGTGGAAGTC
+AAGTGATGGTAAGTACCTATTTTGTTTCAATCAAATTAAATTTTACACCA
+TCTCTCTTTTTTTTCCTTATTTAACAGTCTTTGGTCTGTGTTCTGATGTT
+GAAAGATAAGGGAACATGGACGAGTTGTTTTTGGGAAAAAACATTCTTTT
+TGGATTATTTTAGTAAAAGAAAAATTTAAATTTATAAGCATATTCACTAA
+ATATTTTTGTGGGAATTTGAAAAAAAAAGAAATTAAAGAAGAAACTGATA
+AAAACTAGAAAATGTATAACTGGGAGAAAAAAGTTTCCAATTTTCAGAAC
+TTTTGAAAAATTGTAGAAAATAGTTCATGCTTTCAAAGTTGTAGGAAAAA
+ATAATATGTGGCCAATTTCCGAAAGAAAAAACTCTGCCACGACCAAAACT
+CAGAACTAGACTGAAATTTCAGTTGTAGCTGACAAAACCATCCAAAAGAT
+ATTGTAGGTTACAATATCTAGGCCGTGAAAATTAGAAAACTCGAATCAGA
+TATCCTTGGCCGGAATGCGAAAAAACAAAAATTAGAGTTTTCTAGGCCAC
+AAAAACTCGTCCACGTGTGCATGAACTGTCAAGTGGTCAACGTAAAAGGT
+GTGAAACCCTTCAGAGAAAAACACTAGAAATGAGATAAAGTAGGTGAGAC
+CTCCTGTCTCTGAGAAGCAACGTTCGAAATTCTTTTCCAATTCCATCTAT
+TATTATTATTATTATTATTATTAGGACGGTATGGCGCCAGGAACTGGTTG
+TTTATACTGACCACTGCCTCTTCCCGATTAGGATTCTGAATTTCGGATTT
+CGGGAAATTGAGAATGGCAGATGGATGTAATTTCATTAATCATGTTCCTC
+AATAAGTTAAGAAACAAAAGAAGGAAGATATAGTGAATCAGTGAGGAACA
+AGAACATAGCATATATGGAATTGGCGGTGTAAGACTGGTTTACATGGTTA
+CACGGAGGGAAAAAGATTTGAAAGTATTCGTCATCTTATCTAGGTAGTTG
+AGACACTTGATTAGTCATAGTTGAAAGAACAAATGGAAGAAGTTCATATG
+CTGAAAGCATCGCTAATAACATAATATTGGTTTTAAAGGTGGAGTACGGT
+CTGTGGGTTTTTAACCTAAATGACAGAATACAGTCCCAATATACCGAATA
+TAACTGTTAAAGATTTATAAAATTTATCTAAATTTTTTATGATTTTTAAA
+AAAGTTTTTTTTTTTTTAATTTAAAAATTTATTCAAAATTCCAAAAAAAT
+ATTTTATTCAAAACTAAAAACCCAAATTTTCTGAAACTTTACCATTTTAC
+TTATTTATGTCTTAACAATAATATACACATATTAACGAAATACCCACCGT
+TCAAAATTTGACTTAATCTCCAGTTTTAACTGCCAATGAGAATTTGTTCA
+AAATTCCAATCTCACACCCAATGTTTTTCTTTGTTTTTCATTTTAAAACA
+GTTCTATCCAGTTTAAAAATTTACCAAATAAAAATGTGTCTATTCCTCTC
+ACCTCCAATCCCGTGCATGTGTTCATGTTTACCTATTGAAACGTGTGTAT
+TACTATATAATACAGAACAAATATAAAATGGCCACTCTTGCACCTCCAGC
+GGAAAGAAAGCTTTTGAGGTGTTACGAACACTGCAACACTTTCCTATTTT
+ACTAGTTTTGAGCAATTTTCTGGTCCTTTTATTTATTTTTGTTTTGTCTG
+GAACAGGAAGTTGTTTGTGTTCTGTTTGGAAAATTAATCAGTTCTACCGT
+GAGATTTTTAAGTTATTTTTTGAATGGAATTTCAATTATTATTTCATTTC
+ATTTGTTTTTTTTTCTCACCGAAATCCACTTTTTTTAGAAACAATTTTTT
+TTTCTACATTTTTTTCCGATTTTTGTCATTCAATTTTTCAACTTCTCCAT
+TTTTTCTACAAAACACCGAAAACTACAAAATACCTAAAAATTGCAAATTA
+AAAAAATTTTTAAACATTTTTGCCCAAAAAATTGTTTTTTTTTTCAGAAC
+ATCTAAAACTCACTAAAAAATATGCTCAAAAATTTTTTTGAGAACACTTA
+ATTTTTCGAAAATCTTATTTTTGCAATATTAAATCCAGAGAAATTAGAAA
+AAAAAAACGGTTTTCTACAGTACTCCTACCCTCCCTCTCCAGTACTCTTA
+AAATATTCCTACAGTGTTCTTACAGTACTCTTACACCACTCCTACACTGT
+TCTTACAGTGATCCGATACTACTTTTATAAGACTCCCACAGACTCCTACT
+ATACCTATACCTTATCACTACAGTATCCCTGCCGTACCCCCCCCCCCCCC
+CCAGTACCTATACTTGCCACTACAGTATCCTACAGTATTTCTACAGTGCT
+CCTACACTACCTCTACAGTACTCCTACAGTACCATTACCAAAAATTTGAA
+TAGAAAAGTGAAATTATGAACATTTTTTCCTGTATACCAATTTTTAAAGT
+TTTAGTTTTGTAGTTGTTTTTGACAACGAAATCAATTTCAAAGTATTTTT
+CTTTAAACAATCGTACTTTTTGCGTACTGTTCTTGCACTTTTTGGGATCT
+TTTGGACTAAAAGTGCCCCCCGAAAAAAGCGCGGAATTAAAAGAACAAAA
+ACCGGATAGACTGAGGAGGTGTCGAACGATGGAATGAAAAAAGAAACAGA
+AATTAGATTTGGTTCAGTGAATTCTGTTTCTTTTATTTGGATTTTGGTTT
+TTTGGAGTCTTGGAAAAATGTTTTATTTTTGTTCTTTCCAAGAGTCCAAA
+CGTTTTTTTCCACCAAAACTCCAAAATTTTTAAAATTTGGAAATTTGATT
+CACTGCCAAAACTTCCAGAGAAATTAAATGTTCAGTTTCCCGTAAATAAC
+AGGGTTTCGTATCAAAAACTGTGAATTTTCCCGCCACCTATGTTTTTTAA
+AAATGATTATACTCTAATTTCCCGTCAACATTTTTTTATTTTGCGAAAAA
+TGATTATTTGAACATCCCAGAAAATTTTAAAAACGTCATGAGTTTTTTGA
+AAATTCAATTTTTCGTGTTCCTGTAATAAAAACCATAGAAACTGTTGACC
+TATAACCTGCCAGACGTTCTTCCTGTCTGTTTATACCCCCATCTGCTCTG
+CACACCAGACACCCCTCCTCCTAACTACACTTTAAACTGTTACCCCCCCC
+CCCCCCGTTTACCCCTCATTTGTTTTTTTTTCTAGTGCATCCCTTCCGTG
+TAACCTGACACTTTTTCCAAGAAGCTCGCATTTCTTAGGAGGAGCAGCAA
+TTTTTCGTTACTTAATTTTCCACACAGTAGGAAAGACAAAAAGAAAACGT
+CATAGAAATTAAAAATTCTGCGTTTAATTTTTTGTTCAGTTTCTGAAACT
+CAATTTTGTGGAACCGTTTTTTTCGATCTTTGTAAAATTGAATTTTTTTG
+ATTTTTGGAAAATTTGGATTTTTGCTGGAAAGTCAATTTTTGTGAGAAAA
+GGTTTGGCGGGAAATTTAAATTTATTGAGAAAAATTTTAGCGGGAAATTA
+AATTTTTTGATAGTGAGAAAAATTCAATTGAATACCTTTTTTGTGCGAAT
+TTTTCATAATATCTGAAACTCAAAAAATCTGAAAATTAACTCGAAAAAAT
+TTTCAAATTTGATATTTTGGCAATTCAAAAATTGCTTAAAGAAAATAACG
+GAACCTCGTTTTTTTTCTTTAAAAAAAGGTTTTAGTAACTTTTCCGGTAA
+CCAAGGTTACTCTTTCCCCATCAATCTCCCAAAAGCATGCCAGAAAAAAA
+AGAGAGAGAGAGAGAGATGCGTGTATGATTGTGTCATTTGACAGTGCGCA
+ACAGACACACATAAAACAGCTGACATCTTCTCTTTTTATTTCAACTGATT
+TTTAATTTCCCTCCTTGTGTTCTCTGAGTCTCTCTCATTTATTCAGTTTC
+TCGATTTTCTTCCAAATTCATTAATATTTTAATCTATGCGTAAAGTGGAG
+GAAGATTTCTTCTACGTTTTGATTTGCAATTTCTCGGGTTTTTCAAATTA
+TGGATTTTGAAAAAAAAAATTTCTGAAATTTATTTTTGATTCATGTCAGA
+AAATGAGTCTCCTGAATTTTTTTTGGAAAATATAAAACAAATTCTGAATT
+TTTTTTACTTTTTGATGTGTAAAACAAAAAAATTGATTAGAAAAATCTTT
+ATCTATTTTTTGAACTTTTCAATTTTAAAATCAAAATTAACTTCTAAGAA
+ATAAGATTTTTTTCGGAATTTTGAAAAAAAATGTTGTTTTTTTGAGATTT
+TAGTACATTCAATTTTCGTAAAATTCGAATTCATTTTTTTATTGTGCAAA
+TGTTTTCTGACTGACTATGAGAAAAATTTCAACATTTTGAAGAACCCCCC
+CCCCCCCCCCCCCCATTATTTGGACGGAGCCTGAATACGAAATGTGAGTT
+CTCAGAGAAGGAGGTGAACAATTTGATTGATGTGCATATGGAGATGCTCA
+TTGTGCATATCAGTTTGGAGCATCTATCTCAGAGTGAGCATGACATTTAC
+TTTTACCCATTTGCGTAGGCTCCGCCATTTCACGATTTTTTTTTTCCAAT
+TTTTGAACTAGTATAAAAATTTCTGAAATTTCTGTAATTTCTGCCATCTC
+CTCATAAATTCCATTGTATTCTTTGCACTATTGTTCCACAAAAGTGCAAA
+ATTTTCGAATTCGTAATGTGTCTTTCATATATATATCCATGCACTTTTGT
+CCCTTTTCCTGAATACTAATTTGGTGTGCTCCAAGAGGAAATTTTTTTGT
+TTTGTTGAAATTACTGCTCCTTTTCGGAATTTTTTAATTTCTGAGAAAAA
+TTCAATTCCTAAATGTATAATACTAAAGTCAAAATACTAAAGTGTAATGG
+TTTGTTTTTTGTTACAGTCTTTAGTTTGTAGCTTTTGTTTTGTGTAGTTT
+TCCAACTTTTTTTTTGCCAAAATGAAGGCTGAGAAACCGAAAAAAAAAAT
+TCAAAACATAGATTGGGCTGAAGCGGTATTATTGGTTTACTGTAGCATTA
+CTGGGTTACTCTAGTTTGGCCCATGTTTGGTGTACGTTAGTAGTAACAAC
+ATTTCGTTCATTTGTTTTTTGATTTGGTAACTTCTGGTGATTAAACTTTT
+AATGTACCTAAATCTTCTGTTGCATTATTGATTTGTTGTTTTCTTCTTTT
+TAAGTTAAACATGCTCAAATTAAATTCAAATTGAGTTGAAAATGCAAAAT
+TATTATCAACTTGAATACCCAAAATTTTGGACGGTATTTCAAAAAAATTG
+ATTTCCAGCCGCTTCGACCTTCGACACAACAAACGAATGCTAACTTTCCC
+AGGATTACACAAAATAGGTCAAAATCCCCTTTTCTCAATTTTTTGCACAT
+ACATCCTCATCATCATCATTGTAATGATCGTGACCATCCGGTCTTCTATT
+ATTAAATGAGAGAAGGAAAGAGTATACATATGTGTCTTTTATATTAAACT
+AATTATATTTCGACACATTCTGCGCATATCACTACTGCACTAGAATTACA
+TTTTAAGAATAAAATGTAACCAAAAGACCAAAAAGTTGTTTGCATTTATT
+GTTATAAACAGAATAGAATGAATGTTAGGAAACGTTATTAAAACTTGCAA
+AGTGACACAATTCGGTATATCGATTTCTCTGAAATTACTTAACTTAGTAG
+GCAGAGTTTTGATACTGATACGGATTTTACTAAATTTAATTTTTGTAAAT
+CAGTATTGCTTTTATAACCTATTAAGATTTTTTTGTTCCAGCGTGCAATT
+ATTTTTAATTCTATTTAGGATTTTAATAAATAGAAAAATACGTTTTGAAT
+TATTTTTTACGTTATAATATTCAATAGTAAAGAAGCACACATCAATTCCC
+CTATTCAGTTTCCATACTTTGCCTGATAAACATGAATAGTAAAATAGACA
+CTTTCATTTATACAGACACCCCCCCCCCCTTGCTTCCGGATTAAATCCCA
+ATAAAGGGTGTGGCAATAAGGCATTGTTGCAGTTTCATTGAATTTATTAA
+TCATTTGACAGCATGAAATTACAAAACTGGAGAATTTCTAGTTTAAACTT
+TTATACAATGAAGAAATCTTCCATAGAATCAATATTAAATTATCAATAAA
+TGAGTATTTACGTTTTTCAGCAACGGTATTATTTTTATACTTACTAGTTA
+TTAAGTTAGTAGTTAGTTACATTTTTAAATGCGATGCAGTCGAAATTTTT
+TTATAGACTAGAAATTGTCTTAGTTTCCAGCCACTGACAAGTCGGCCAAA
+TTTCAAACTTTCAGTAATTTTGCGTCATTTGTTGAGCCGCCATAACTCTT
+TTTTTGAGACGTTTTCAAGAAGTTGAAATTTGGTATTTTCAGACATTTGT
+ATCTTATTTAAAATATGAGTATTCACTCCTTTTACCTGCCAGTCGGCTGC
+CTCCTTATCTCCTATTTTTCTCTAATGAGCACACACCACTATCATCATTA
+TTATTACCACCTGTTCTTAATAATAAACATTTCCCGCACTTTATTTCCAT
+TTCGATGCATTTTATAGAAAATGTTCCCCCTTTTCGAGCTTTCCAATTAG
+ATTCACCCTTTGATTGCTCTTTCTTGGACGGAAGTGTTCCCCAATTCCCC
+TTCATCTTATTACATTTTTATGCAGATTTTATTGCATTTTAGTGCGCTAG
+ATTTTTCATGGGATTTTGCTAAATAATGCAATCACGCTCTAAATAAAATT
+CTCAGTTTATATTTTAATGTTAAAACTGTGTGTAAAATTTACAAACATAG
+TGAATACATTTTTCGAATAAAAGTATGAACATTTTTCGAGGGATCTATAG
+AAAATTGCCGGCTGTTCCTAAATGCCCTTTCACTGGTCACCAAGTTCCTG
+TTCATGCAATTCAAAAGAAATGTTCAGCCCCCCGCTCAATAGTCGCCCGC
+ACCACAAAATTGAAAAGCGAACATTTTACTAGTCGAACTTTTGAATTGAA
+CATTTTTGGAGTATTTTAAAGAAATGTTTTCAAGTCCACCAAAACATATG
+CCAGGCCACAAAAATTTCAATTTTCCGCCAATTTTTTTCTCACAAAAGTT
+GAATTTTCTCGAATTTCCGATAATTTTCGATTTATTTGAAAGTTATTGAA
+ATTTATATTTTCTAAAACACTTCCACAATAACAAATTAATAGATATAATA
+AAATTTGAAATTCCCATGCCACACCTCAAAAAGTGGCTCCCTTAACTCCT
+GAGTGCTCGCGGAGCCCTACCAAACTTGGAACATTCTTTTCCCAACGGAG
+TCATGAACATATGAGCATTAAATGAGTAGACGACATGTGTATACATAGGA
+CCACCACAGCTGTTCCTTCCTTTTTATGAGAAGACATGTCATACACACAA
+TGTCTCTTCTCCTTTCCGATTGGAAAATTAAAATTATAGGAGGGGGGGGG
+GGGGGGGGCGATTCTTGACATTTCAATTACCCCCCCCCCCCCCCCACATC
+CGTTATGTTGCATTTTGGTAGGCTTGGGGCCGAATAAGTCTCCCATGCAG
+GCGTCAAAACGTCTGCGGACCTACGCCTGCCTCACGCCGCGCCTGCTGTA
+CAGGAACCCGAAAAGTGTCGAACGCGGCTAAAGAACCACTTTTCGCACTA
+TGCGGTGTAAACACAAGGTTTTGATTTGTAGTCATAGTGCATATATGATG
+CGGGAGGCTGACAGGTAGGAGGCAAGCGTTCAACCGCGCATGCCCACCAT
+GGAAGCCCTAGAGCCTAGTTTTAGATGAGTTTCAGCATTTTTGATCTACA
+AGATTTTGAAAGTTTTACAAAAAAACCAAGATTTTTTGTAATTTATGAAG
+TGATTTTTCTACATTTCATCTAGAAACCAGCAGAGTTATTTTTTGGGTAA
+TTTATCAATAGAGCGCGTTCGCGTCATGAAAACAAAATGGCGGCCGAACT
+TTGAAAATCGATGGCTGAATTTTTCGGAACAAAAGTCCGTAGCTATAAAG
+CACAGGCCTACGTTTTTTTTGCTTTTAAATGACATAGTTTTCTAAAAAAA
+AGTCTGTGGCCGAATTTTTAAATTTTGAATAGGGGCTTATTTCAAAAAAA
+ATTTGAGGCCAACCTACTCTTCTCAATTATAACTTGCCATGGCAGAACTT
+TTGAACAACTATTACAACGTTTTCAAAAAACAAGTTAAAGCATTTTTTCG
+AATAAAGGTTAAATTGGTAGCCTAGTTTTCTCAAAACAAAATACTAAAAA
+AAATATCGATGACCGAAGTTTATATTTGAAAAAATATGTGACCTAGAACT
+TTTAACTACTCTTCCAATGTCTTCTAGCTTCTGAGAAAAAGTTCGTGGCC
+TAAGTGTACCACGATGGTCTAGTTATCTCGGAAATAGCCATAGCCTAGTT
+TTCTCAAAAAAATCGGTGGTCGAGTTTCCTGTATGTAGGCATGTAGGTAT
+GTAATTTTTATCTTCCAGGTATCTATTTGTACTTCCCGGTAGCCAGGAGC
+AATACTTTTGAATTCCTTTGCTCTCCCTATTCAGCTTCTCCCCTCACACT
+CGTTTTTGGTATTCTATTGTTCTCCTCCTCTTCCCATTCTACCCCCATTT
+CATTTTCCTCTTGGAGACCCCTGTCTCTCTCTCTTTGTATTGGCTCTTTT
+ACGTCTTCTAGTAGGCTTTTCCTTAATGAACTTGTGTGTGTGTGCTTGAA
+TCATCATCGCGTTCTCTCGTTCCATTTCCCTTTTGCAATTTTCTTTTCTT
+GGAGAAATTTGGAAAGTTTTGCTCAAAATTCCTACGTACACATGCCTCAA
+AATCTGGTTGTATATGGCCTAACATTCAATTTCTAGTGCACACAATAAAA
+TTTTCCGGGAAATTCAAATTTTCTGATAATGAGGAAGGACTTTGGCGGAA
+AATTCAAATTTTAAAAAAGTAGGCGGGAAATTCGAATTTCGAATTTTCTA
+AACTTTTTGGCCGGAATTTCAAATGTTCTGAAAAATAATTTTGGAGCGAA
+ATTCATATTTTCTCAGAAAAATCTCAGAAAATTTGAATCTCCCACTAATA
+TTCTTCTCAAAAAACTGTTACGTGACCTATTTATATCTTATTTATTGGTC
+CATTTATTACGTGGCCTAAAACATTTTTTCTTTTCCCCCGTTTACAGCGA
+TCATTTGAGATGGCCTAGAAAACGCACGTTAGGCCATCAGGTTTACGGGG
+TATAGTACAACCTCTTGCAGGGGACTGAGGTTCAGAAAACTACAAATTTA
+GCTAATTCCCTACCTACTCTTGCAAATCCAATAACTAACCCAATTTCCCG
+GGGAAATTTTTATTCTTAGAAAACAACTTGTATATCTCCGCAACTACATA
+TCCCTCCTTCAAAATAATAATAATGGGAAGCTTCTGCTTCTCTACACCTT
+CTTTTGACCAAAAACTTGTTGCCAGTGCCCTATTATGTACGGTCCGTTGA
+GTTTTGTTGTTGTTCACAATAATATGTGTAATTCGCGCATCTGAAGAGGG
+GAGGTGTAAATGTTGTGTCTAACCGTTATGTTGCTGTCACCTCCAAGTGG
+TACAGGTGGCCTAGAAATTTGCGAAAACTCTTCCACGATTATATTTCTCA
+AAAAATTACTTTTCTCAGAAAATTTGATTTTCTCACCAAAATATTTCTCA
+GATAATTTGAATTCCCGCCAAAATTGTTTAAAAAAATAGAATATCTCGTC
+AAAATTTTTATCAGAAAATTTGAATTCCCCACTAAAATTTTGCCAAAACA
+TTTTATTTTCCCACTTAAAAAAGTTTTTTTTTTAATTTGAAAGTGGAAAA
+GTTTTCTAGGTCACTTATACATTACCGGTGACCGAGGTCGAATTATTCCT
+AGGCCACAAATCTCCCAAAGGGGTATTCCCACACCTAATTGACACCTCCC
+CGGGCACCTTTGAGCACTAAGTAAGGACACCCACCCCTCTCAGCTTAATA
+GCTTTTAAAGGAGCACACCAGCCATATGTTTTCTCTAATTCTCTCACTCT
+CTCTCTCGGCTTCTAAATTCAATTTCCCCCCGTCACGCCTCTCGTTACGT
+GAGGAGTGTTCAACATGTTCCCATTCCCTTATCCGATAAGTTTTTGGTAG
+GCAGGAGCTTGTACTAGTAGAGGACATTTGTCGCTTCTTGGTCTTTCGCC
+TCCATTTTCCGTAATTTATACGTGACTTAGAAAATTAGAAAAAAACGCAT
+TCCACGAGTTTGTTGGACAACTTTTTTTACGTGGCCTAGAAAAAAATGAA
+ACTCGGCCACCGACTTTTCTTTCACTTTTGTGAAGATATGATCTCATTCT
+ATAATTCTGTCGAACCGATTAGGAGGGTGGCTGAGTTTGCACTTTTGCGT
+GTTCTATACCATTTACAGAAGCTAGTCCCCCCGTCATTCTTTTTCCTGCA
+AAATGTTTTTTTTTGCCCCCGGTGTCTCATCATACAGTACAGCAGCCAAT
+ATTATTTGTTTTTTGTTTCGTCTTTTCGTCTTTTCGGAGAAAAAACGCTC
+TATTCTATGACAAGGTGACGTCATTGGACTCGTGGCCTAGAAAGTTTGGC
+AAACTCTTCCACCATTCGATTTTACAGGAGCCTCAAAGCCCCACATGGGG
+CCTAGAAATCTTGACATTTCTAAAAAACATCCATTTTGAAATTTTTCGAA
+ATTGGTGCAACCTAGCAACCTCTAGAACTTCACGTGACCTAGAAAAAACA
+AAACCTCAAAATTTCATGTGGACTAGAAACTTTTAAAAACTCTTCCATCG
+ATTTTGTTTTGTGGCGGGGACTTTTTCCAGTTTCTTTTTCACATAAAAAC
+CAAAAAAAAACAAGACGTCAAGCTGTGAAAATGATTAGTCACAAAAAGAA
+GAAAAACAGTAGTGTCGTTCCTGCCAATTTCAGAGATTCCTTCTTCGCTT
+CTCACGACACGAGGGGGGGAGGGTCTAATTGGCACCCCCCCCCCCCCCTA
+CTGAGGTGAGAAGCTTGAGTTGACTCACACGTCGCTCTTGTTTTATTCAT
+TTTTGGCACAAAGTGAAGTGTGCGAAAATTGTAGTAGTCTGTGTGTGTGT
+GTGTGTATGAGCATTTCGAATTTTAAAATACTTTTTTAATGTACCGCAGG
+CCACGTGGTAAGTTTTTTTTCATAAATATAGGATTTGTTTTCTTGTAGAA
+AAGTTTTTCGAATTTTGAAATGAAAAGGATAACTGGGAACGGAGAAAAAT
+TAAGTTTTAATTTCTAGGCCACGTACCAATGAGGATGAGAAGTCGGTTTT
+CTAGATCACAAGGTCATCTAAACTTTTAGGAAATTTAAAAAGTTTGGTGA
+TTACGAGAATTTCTAGGCCACGTCGCAATACACCGGCGCGTTGGCGTTTT
+TACACTTTCTAGACTACTAAGATTTTCCTAGGCCACGTCCCAATCAGGGC
+TGTTGCAAAAAAAAATTTTCGACCAAAAAACAAAAAACAAAAAATTTTTT
+GGTCTAACTATGGACCAAAAAACAAAAAACAAAAAAACAAAAAACAAAAA
+AAAATTCAATGTTTGATATTGAACGGGACAAAACGGAATTTTTTCATGAA
+ATATTCTGGTGATTTTTTATAAAATATTGAAAATTGAACGAACAGAAGGT
+TTTTTGTTAGCTTTTTTGCTGAATCAGTGCTGTAATTTATTTTTTGGTTG
+TTTTTGGTTTTTTTTTTGGTCTCAAAAAACCAAAAAAACCAAAAAATCAA
+TTTTTCCCAAAAATACCAAAAAAAACCAAAAAAAAACAGCCCTGGTCCCA
+ATGTACAGGTGTTGTGGTGCTTTTTGTGAGCTCTTAGGCCAGCTGGAGTT
+TTCTAGGCCACTTGTAAATCAATGGTTTTTTTTCGGTGTTCTAGGCCACC
+TGTCACGCCTAGACCATTGACCTAGAAGTTTAATGTTTTTGAATAATAAG
+TACACGTACTCTCACATACCCGCAAATGCACATATCTATCTTCATTTCGT
+GATTCTCTTCATCTCATCTTATTTTCCATTTCGGTTTACCCTTTTTTTCT
+CTATGAATATATTTTCATGTACTTGCTCTTCTTCCCTGAAAAAGATTCTT
+TTACACTTTTTTCATTTCCTTAGGCAGTTGTAAAGAACTTGTCATTAGAA
+CTTTCAGAATGACATCAGAGTAGATGGCCGAACTTTTTCTAGGCCACGGC
+TTGGGAGCCAAACATGGCTAAACATTCTAACTTCCTGGGTCATCTAGAAG
+TTTCTAGGTCTTATGGGTGAAAATTGTCAAATGACAGAATTTTCTTAAGT
+TATAGTTGAATTTCCCGCCAAACCGATTTTTTTTTGAAAAATTTAAATTT
+CCCGCCAAAAATTTTTTGAAACGTTTAAATTTTATGCCAAACTTTTTCTG
+AGAGAATTTGGTTTCGCTCCCAATTTTATTCTCTGAAAATTTTAAATTCG
+CACCAAATTTTTCGAGAGCTTTTTGAAGTTCCCGGCAAAATTTGTTTTCG
+AAAAATTAGATCCCCGTCAACTATGATAGAGAAGTTACGTCATCTGGCTA
+CCCTGGCCGAATTTTCAATATATTTCTAGGCCACATATTGACCGCTAAAT
+CATGTTGTGGAAGAGTAGTGACGTCACTTGGCGACCGCGACCATCGAGCA
+GCGTGAGGGGCGAAGTATCCCCCTTCCCAACCCTAAAGACGTCGTTCATC
+GCTCCTTTTTTGTTGTTGTAGGAGTTCCGTTTTTTTGTGTCTCGATTCGT
+TTCCTCCTGTTTGTTGTCATTTCTGAACTCATCTCTACACTTCTCTCGTC
+TTCTCTGCGTCTCTCCATCCTGCACACTATTTTTGTTTACCTCGATGATC
+TTTCTTTTTGCGTGTGTGTCACTGACGAACGAACGGCTGACACAGACTAT
+TGTTTTAGTTTTGTTGTTTAGAAGTAGTTGTAGTATTCCAATAGTTTTTC
+ACACTTTGCATTATTTCAGATGGCTCAGGACGGAGACCGCCATCACATTT
+TTGTCAGTGCTCCGCCGCCGCCGCCACCTTCCTCGTCGATTCCAGCTCCA
+TCGCAGGTAAATTTAAGGTTGCAAGCGCGCTCTAATGACCTTTTTTGTGC
+CTCCGGCTCCTCTTTGGGTTATTGCCAACGCGCTCCAATTCGAATTATTC
+TTACTTTCAGCCAAATAGACTGGAAAAGGAGCCGCTCATCGATGAGGAAA
+CTGACATGATTGACGAATCCCGAGCCACGTATTGGAAGGGATGTGAATTC
+TTGAAAGCCTCTGGGTTGTACTCGAGTAAATGTGAGTTGGTCTAGAAAAT
+TTGTAAAGCTCTTCCACGAAGTAATTAATAAGGGATACTATTGCCGACAC
+CCAGGAACACGTATACCACGGAATTCAAATTTTAATTTTTTGAAAATATT
+TTGGCGGGAATTTAAAATTTTAATTTTTTGAAAATATTTTGGCGGGAATT
+TAAAATTTTAATTTTTTGAAAATATTTTGGCGGGAATTTAAAATTTTAAT
+TTTTTGAAAATATTTTGGCGGGAATTCAAATTTTAATTTTTTGAAAATAT
+TTTGGCGGGAATTTAAAATTTTAATTTTTTGAAAATATTTTGACGGGAAT
+TTAAAATTTTAATTTTCTGAAAATATTTTGGCGGGAATTCAAATTTTAAT
+TTTTTGAAAATATTTTGGCGGGAATTCAAATTTTAATTTTTTGAAAATAT
+TTTGGCGGGAATTTAAAATTTTAATTTTTTGAAAATATTTTGGCGGGAAT
+TTAAAATTTTAATTTTTTGAAAATATTTTGGCGGGAATTTAAAATTTTAA
+TTTTTTGAAAATATTTTGGCGGGAATTTAAAATTTTAATTTTTTGAAAAT
+ATTTTGGCGGGAATTTAAAATTTTAATTTTTTGAAAATATTTTGGCGGGA
+ATTTAAAATTTTAATTTTTTGAAAATATTTTGGCGGGAATTCAAATTTTA
+ATTTTTTGAAAATATTTTGGCGGGAATTTAAAATTTTAATTTTTTGAAAA
+TATTTTGGCGGGAATTTAAAATTTTAATTTTTTGAAAATATTTTGGCGGG
+AATTTAAAATTTTAATTTTTTGAAAATATTTTGGCGGGAATTTAAAATTT
+TAATTTTTTGAAAATATTTTGGCGGGAATTCAAATTTTAATTTTTTGAAA
+ATATTTTGGCGGGAATTTAAAATTTTAATTTTCTGAAAATATTTTGGCGG
+GAATTCAAATTTTAATTTTTTGAAAATATTTTGGCGGGAATTTAAAATTT
+TAATTTTTTGAAAATATTTTGGCTGGAATTTAAAATTTCTGAGAAAAAGA
+ACCTTCGTGTCGAGACCCATCGTGGTGAGACCCTTCGTGGTGAGACCCAT
+CGTGGTGACACCCATCGTGGTGAGACCCTTCGTAGTGAGACCCTTCGTGG
+TGAGACCTTTCGTGGTGAGACCCATCGTGGTGAGACCCATCGTGGTGAGA
+CTCATCGTGGTGAGACCCTTCGTGGTGATACCCATCGTGGTGAGACCTTT
+CGTGGTGAGACCCACCGTGGTGAGACCCATCGTGGTGAGACTCATCGTGG
+TGAGACCCTTCGTGGTGAGACCCATCGTGGTGAGACCTTTCGTGGTGAGA
+CCTTTCGTGGTGAGACCCATCGTGGTGAGACCTTTCGTGGTGAGACCTTT
+CGTGGTGAGACCTTTCGTGGTGAGACCCATCGTGGTGAGACCCTTCGTGG
+TGAGACCCATCGTGGTGAGACCTTTCGTGGTGAGACCCATCGTGGTGAGA
+CCCATCGTGGTGAGACCCATCGTGGTGAGACCCATCGTGGTGAGACCCTT
+CATGGTTAGACCCATCGTGGTGAGACCCTTCGTGCTGAGACCATTCATGG
+AGAGACCCATCGTGGTGAGACCCTTCGTGGTTAGACCCATCGTGGTGAGA
+TCTTTCGTGGTGAGACCCATCGTGGTGAGACTCATCGTGGTGAGACCCTT
+CGTGGGGAGACTCTTCGTGGTGAGACCCTTCGTGGTTAGACCCATCGTGG
+TTAGACCCATCGTGGTGAGATCTTTCGTGGTGAGCCCCATCGTGGTGAGA
+CCCATCGTGGTGAGACTTTTCGTGGTGAGACCCATCGTGGTGAGACTTTT
+CGTGGTGAGACCCATCGTGGTGAGACCTTTCGTGGTGAGACCCTTCGTGG
+GGAGACTCTTCGTGTTTGATATTATATTGGCGGGAGCTAAGGAGTTGGTG
+TGGGATAATGTCAAGGTACTCTAGGGGTATTGTGGATTTGCTGTAGGGTT
+ACTGTAGTTCAGAAAAATTGACTTTGTGCTTTTGAAGAGGTATTGGCTCG
+AGAGTTAGAGAGGCGGAAGCTTCTGTGATATTTTTTACATTCCAGAATGT
+TTGAAAAAGTAAAAGTTTCCACCTGTTTTCATGTGACATTGTTAAAAGAT
+TATATGGTGTTTTATGTGTCGAACAATTTAAATTTCGCCAGTCGTTGGCC
+GCGCCGTAGGCGCGGTCAGCGGCTGGTTTTTCCAGAAAAGGAATAAGAAA
+TAAATTATTTGGAAGTTACTAGGACCCTGAATAGAATTCTAGGCCATATC
+GAAAAAGGGGATGGGTGCACGTGGGAACCTTTTTTTGGATATTTTGGAAA
+GAAGTAAGAAGTAAGAAGTAAGAAGTTGACTTAAGAAGTTGACTTTTCTA
+GAGTAAGAAGTTGACTTTTCTAGAGATCATCTCCCCTCTATTATTCTCAG
+CGTGACCTAGTTATCCGGAAAACTCTTCCACCAAAAAATGAGTGTCTCCA
+ACTGAAAAATGCGTCATAAAACACACGGAAAAGGTACTTGTGTATTACAT
+GCCCTCATTTTAATAGTAGTTTTTTAAGCCATGAAAAATAAAAACGTGAA
+CCACAATTTGTATTTTTAGGCTTAGGAAATAACATTTTCTAAGCCTAAAG
+AGGAAAATGTGTAATACACAAGTACCACGGAAAATTTTTTGAAACCTTCC
+GAATTTGAAATAATTTAACTAAAAGTTTCTAGGCCACGATGAAAATAGAA
+ACAATGATGTCCCGATTTTGCTGAAAATTTCTGTCCATAGTTATTTAGAG
+TTCTGAAAAAAAAGATTTTCGAGAAATGATTTTCTAGGCCACCAGAAAAG
+TTTCTAGGCCATTATCCCTTCTTGATCCTTTATCATTATGATTATGATAT
+TTTTTAAACGATTTTTTAGGCCACCAGAGGGAATTCTAGTCCGTGTCAAA
+AAAAAAAGAAAGGGGGTATTCTTTCCACATAAAAATCCCGTTGGCCTTTT
+CAATCAAATTTCTTCAATTTTTCGCATAAAACTTACCTCCCGCTGTGACA
+AGCCTCCTCCCGTCTCCCAGTATTCTCAATTCATTAATCATCACCCCCAA
+TGCCCTCATCAACTACAGTATCCCTGCAATCCGCGTCTGCAAATATGTGC
+CGAATATGTCATACTTCTACGTCAACGCGGTCAAATCCGCTCATCTCACC
+GTGTCGATGCTCTGGAACACTGCTCTTTGTGCATAAGGCGTGTGTTGTGG
+TGAGCTCTTTTTTTGTAAAATTCAAAATAATAATTAAAAAATTTAAAAAA
+AAACCTTTTGTGGAATTTGCAATTTTTATAAAATCGTTAAAAACCAAATT
+CAATTTATACAAATTTCCACATTTTCCAAAATAAAAAGAAATAGCCATGC
+CCACAAAATGGGCGGCGCTTTCATAGCCACGTCCATTTTGTGGGCGGAGC
+CTCGGATCAAAGTTTTTTCAAAAACTTACTATAAGTTGAACACGGATTTC
+TGGCTTCCTTCATAAATCGAAATGGCAGAGTTTGCCGAACTAGGCCATTT
+TGGGTCGGAGAGATTTTGTGTAGATTTACGGCGTGTTGCGTGTCGCGTCG
+CGGCTCGTTTTTAGTTGTAAAACTGCTGTATTTGTCCGTGTGGAGTACAC
+GATTTTTTCCACGCGCTGTCCGGCAGGCGATTGTCAATGAGGAGCGAAAA
+TTCAATGCGAAAGGCCAGAAGCCCGTGGTTGAAGTGTGGTTTCAATATTA
+CAGAAATTTTAAAGAGGAATAAACATGCCTGCCTACAAAATGGGCGGAGC
+GTTGGAGGCGTGGTCTAAGAAGTCACGCCCTTTTTTTTAAATACTTGTTC
+TGATGTACAATAGAGCGCATTTACATCAAATTAATAATTTGTTTTTCAAT
+TTTTCCAGAGATGGCTGGAAATGTCGACTCGAAAAATGGTCCCATCACCA
+CGTTGCGAACTATGCGGCTACGATTATCGACGTGGAAATATATTTCAAAT
+GAAATCTTTACATGTTCCACACGTGGATCGATCATCTTGTCTGCTCAATG
+TGCTCTTTTTGATTACCGTATTAATTATGATATTTTGTGGATATTTTACG
+ATTCAATTCATTCAGGAGAATGCACTCTTAAAACGAAGGTGGGCGAAGTT
+TTCTGGTGATGACCTAGGAAATTAGAAAACTAGGCCACCCCGCAAATGTG
+GTGGCCTAGAATACCGAAATTTGACTAAGCTATGGCCTGCGGCCTAGAAA
+AATAAAAGTAGACTGTATAAAATTCTCATCAAGCCTTTTGGAGATGAACT
+GGAAACCCAAATTTTTTGGAAGAAAATATTGACCTCCTTTAAAACGGTGG
+CCTACTTTTTCTGATGGCCTAGGATTTTAGACAAAGAAGCCACACAGCTA
+CTATCCACATAGTTTCAGGAAAAAAAATAAGAAAAATAGGCTCCGCCCAC
+ATATTCTTTTGAATTAGAATATACACGAGCCATTTATTTTGCTAAGTTTT
+GAATGTTAGCTCCGCCCACATAATGATTTGAATTTCCCGCCCATTTTTCT
+CTCAAAAATTTGAATTCCCTGCCAAATTTTTTTTTGCGAAAAACTCAATA
+CTTTCAGGCTCTTCGCGCACAGTTCGACAAACACAGCGTACACGTGGAAA
+CGGCGTGGCTATTTCAGCGGAAACGGGAATGGAGACGGGGACGGTAGTTC
+GGATGGATATTTCTCGCGTACACCTGTCTCATCACTTTTTGACATAAAAG
+TGGTCTTGTGTGCCAGCATGTTCTTGGTCTCGTTCATTTTGGCCCTTTTT
+ACACAGTATAAGTGAGTTTTTTGACACGTGGCCTGGAAAATGAGAAAACT
+CGGCCACCGATTTTTTCAGCCGAATTTTTTTAGTTTAGCGGTCACACGGG
+CTTCTGGCCATTCTCTCTGCATTTTTCGCGCTCCATTGGCATTGGCTTGC
+CGGACAACGCGTGGGAAAGTCGTGTACTCCACACGGATAAATTTGTTCAG
+TTTTACATTGAAAACCGAGCCGTGACACGCCGTAAATCTACCCCGGCCGT
+GGCCGAGTCAAAATGGCATAGTTCGGCAAATTCTTGAATTTCAAAATATG
+ATGGAAGCCTGAAGCACGTGCGGTCATAAAAATCAATAAATTATCTTTTT
+TTTCCAGAGCCGAGTCCACGATATTCCGATGTATTTTCCGATTTTTTGTG
+ATCAATAAGAATTGGATGATCAAAAACTACGATATCAAGTGAGTGGGCGG
+AGTGTAATTTCGGCGGGAAATTCAAAATTTTTCAAATTTTTCAGAAAAAT
+TTCGCGCAAAGTTCAAAAACTCAAAACTTTCGGTAAATTTCGGCGCGAAA
+TTCAAAATGTTAAAAATTTTGGGGAAATTTTGGAGGGAAAATCAATTTTA
+AAAAACGTTTGTTTGAAATTTTTTTAATTTTCAGAAATGATCCCGAAATG
+GCTCACCGCCGCGGTCTCCAGAAGTCTTCACCTGTTCCGTTAACCTTATC
+AGCTTCTGATATGTGTATCCACGTGTCATCCTAGTCAACAATTCAACGAA
+AAAAACCATTCCAGTTACAATTTCTCATTTCTTTTCACCACTTTCGGGTT
+TTTTGCAAATTAAAAAAATTTCGATTTTTTTTTTGAAATTTTAATTTTCC
+AATTTTTATTTTTATTCCACAACTCAGGTTGCTCAACAGTGCCTAAAATA
+AATTTTATTTCTTTGATTTTTTATAAATTTACAAAAAAAATACAACAAAA
+AAATAATATTACACATTCGTGAAAAACGGAAAAAAAATTCAGCCTATTTA
+CATTAAAACACGTGGAATTTGAAATTTTAGCGATATATCGATTACCCTTT
+CTCGGAAAACTCGTAATAAATGTGAAAAAGGCGAGGAAATTGGAAGAAAT
+AAATGCGGGGGTTTCTAGAAAAAAAAATTGGGAGAAAGTTTAAAGAAAAA
+TTCAAAATAATGCTCCGGTGTCATCGTGTTCCACAGTGGTTAGATTCTGG
+TATTTTGTGCATGGTGTGCTCTGAAATTTAAAAAAAAAGTAAAAAATTGA
+AAAAAAAATTTCTTAAAAATTAAAAAAAATGAACTTTTTTTTAAAATTTA
+TATTCAAAAATAAAAATGTTTGGTATACCTAATTATTCATACTTTTATCA
+ATTTTCGAGAAACTTCAATTTTTCAACTGCTAACGTATACAACTCGCGTT
+ACTCGAAAAAGACCTGGGGACTAGTTTCCCACTTGGTGGCCTAGAAATCT
+CCAGTAAAAACATCGACGACCGAGATATGAGTTTCTAGGCCTCCATATGA
+AAAAAAAACTCGGTCGGGGACTAGGTTTCCACATGATGGCCTTGATAACT
+TCAAATTTTTTGGTGACCTAGATTTTTCAAAACTTGGATTACTAGGCCAC
+TAAAAGCTTTTCGGTGGCCTAGAAACCAAAATTGCGTGAATTTTTCATAA
+TTCTATATCAAAATTGACTAAACCGAAAAGAATGCGATGCTTTTGCAATA
+TTTCAGCAGTTGGTGTATCCCACGTGGCGACGGGATTTCGGGCGACCGTG
+CCATTGATTAGAGCCAACGGAAGATATTTTGAGCATTCGGCGGTGCTCTG
+CAAAAATTTTTTTTTTGCAAAAGTTAAAGACGCATGGTGGGTCTTGATCT
+ATGAAATTTCGTGATTATTCGAAAATTTTTTGTCCTTATTGACAATTTTT
+TTATCCACAAAAAAGGCGGATGTCCTAATTGCCAAAAATGTGGGTTTCTA
+GGCCACGAAAAATAATTTTTTGCTTCAAACATCCTGCTTTTTTTCCAAAA
+TTTAGCTTTAAAAAGTCGGTGGCCGAACTTTATTAAAAGTTCAATTTCTC
+GGCCACAGAAACTTTGTTTAAGTTTTCACATTTGGATTTCTAGCCCACCA
+ATAACGTTTTTATTTCATATTTTTATAAAAATCGAATTAAAAGTAGATGA
+TGACCTAGTTTTTTTTCAATAATTTGGGTTTCTAGGCCACCAACTTTTTT
+TAAAAATTTTCTTAATTTTCCATAACCAAAAAAAAAAAACAAAATCGATG
+GCCTAACTTTTTGGCTTCCTAGGCCACCAATAACTCTTTTATTACTAATT
+TTCCTCACTCTCTGATGTCGATAAACACTTTCTTGTCTCGAATATCGCTT
+CCCACACCCATCACACTCAAATGCTCCATTCGTCTCATGAGTGAGCAAGT
+GTTGATTGAGCCCATGCTTTTGCCGGAAAGTTTTCTCGCAGTCTCGACAT
+TTATAAGGTCCATTGTTGGGCTGGGCCTCGTGAGCCGACGACGGGGCCGC
+CCGTTTTTTCGCCCTTTTCCCCGATTTTTCCGGTGAAAAAGTGTCGAAAT
+ACGCGTTATTGTCATCTAATTTTGGTACATTCGCCAACATTGCTAGATTC
+TCCTGAGCCACCTGTTGTGACGTGTGAGGAATGTGATGGTGCTGATAGAG
+GTCTGGTGGTGGCTGAAAATGGGGAATATTCCCGGCGCCGAACATTTTCA
+GAAGTTCCAGGTCGAATCGTTGTTGAGCATCCGCGTCGACTACTTGATTG
+AGGGAGACGGTGAAGTCAGTTGAGGAGGTGGATGGCAGTTTTATAGAGAA
+ATCCTGCAAAAACTCAGGTTTTTGCTAAATTTTTCAATTTATCATTGTAA
+TTTCCGAAAAATTATAGCTTAATTTTTAGATTTTTCGCTTGATTCTCAAG
+TTTTTATGCGAAAATTTAGTTTTTTGTCAATTTTTTTTTGTTTTAAATGT
+AAAACTACGGTATTTAAAGGGAGGAGCACTAATTTATGCCGATGGGTCTC
+GCAGCGAAAACATTAAATGCCTTAATTTAGCCATGCGCCTGGAAGGTTAC
+TGTAGTTTTTATTGATTGATTTTTCATTCAATTTGTGGTTTTTGAAGGTT
+TTCAACTCATTTTGAAAGGCTTTTATAGATTTTTTTTTCTGAAAATCAAA
+TTTAAATGTTAAAATAATTTTTTTTTTTTTTCACACAAAAATAACAGAAA
+TTCCGAAAAATTGCAATTTAAACAGCTCTAAAATATGAAAATTAACGCGA
+TTTTTATCATTTTTTGCTTCAAATCGCTGACTTCTGGCAAAAAAAAGGAA
+AATTCAGCAAAAATCAATTTTTCAGAAAAATTTGATTGATTTTTGGAATT
+TTTCTTACCAATCCGTCGTCTTGCCGTAAATCCTGTAGCTTCATCTCCTT
+AGCCAGCAGATTTCTTACATCTAATTGCACGTGGCAATTGCAGTTCTGAA
+AAAAAAATGTTTTTGAGATTTTTAGAAAACTTATTTTGTAAATGTTCTAG
+GTGGGTTTTCAAATTTTTTTTTAAATTTAATTAAATCAAATTCTTCTCAC
+CGTCAGTTTCTCTTTGACAAAATCGCTCAAATTCTTCTGATTTTCCTGAA
+CTTTCTCCACTTTCACGGCCAAATCCTGCTGCTCACGCAAAAATTGTTTG
+ACAAGACACGTTAGCTGGTTCACATTTGATAGATTGTCCGGGATTTTTAT
+AATCTGAAATTTGAAATTAAGGATTTTAGCGGTTTTTTCGGCAAAACGTA
+AACTTTTAACGCTGAAAACTCACATTTTTCGAACTCCGCTCCAATAATCG
+TCTAGTGAATTCTTGAATAAATCCGGTTGCTTTCATAAAATTCTGAAATT
+CCTCATTTCCAATGAATTCGCCCATTTTCCGATGGAAGAAAAACCAATGG
+AAATACGGCAATATTTGCGCACAAAATCGATGCTGAAGTGTCGTCGGACG
+CAGTGTTTCGTGTGCAGTACACGCCTACGACAAATTGCGGACTTTTTTGT
+TATGGAGAGAGTAGAATAGAGAAGAAAAAAGAAGATAAAATGGATAAAAA
+TTGCGCGTTTTTCTCGTTTTTTCTCTGAATCTCTCAATTTTTAGGTTTTC
+GATCCATATACGTCCCGAGTGGAGATGAAGCCATAAATTTTTCTCTAAAA
+ATTGTTTCTTGCCCCTCCAAATCGCTTATTCGTTTTTAAAATTATGAAAA
+AAAAATGCTAAAAATGCTTACCAAACCGCAAATTTTTAATTGGAAAATAC
+CCAATATTTTGCAATTTATAGTTTAAATTCAAGAAGGTGCCAAAATTTCT
+GCAAAATTGCATATCTTCATATAAATTGTTACATTTTTTGTAAAAACTTG
+AAAACCCTGCTTTTCACATAATAGTACTGGAATTTTTCAATTTTCAACAA
+TTTCATAATTTTTGACCAATTTTTTATTGAAATTTTCAATAAAATATTTA
+AAAGATGTGGCTTTCCAAGCAGATTTTCCAATTTTTCCGAGTTTGAGTAA
+CTAAGTTTCAACCAAAATGATGTCACAAGTCAGAAAATTTCCCTAAATTT
+CAAAACACAGGTGAATAACTATAGGATTAGAATCTGCAAAGATTGAGTCT
+GGAGATAATTTCGGACATTTTTTCGGATAGTTTACGTTTCCTGTAGTTTC
+AAATAGGCAATTTTACTTTAAAGGTTGCTAATAAAATTAAGAAAAATCCT
+TATATAGTCTCCACCCACAGATTGGCTTTTTAGATATTTTCAAAATATCT
+TGTAACGAAAACTACAGTAATCTTTAAAATTAAAATTATTACTGTATTGC
+TTTTGTCCATTTACGGGCTCGATTTACGAAATTAAATTTAATAATCTTTA
+ATCTATAGAATATTAAAATTAAGCAAAAAATGAGAAAATAATACGAAGAA
+ATGAAGGAAAATGGAATATCGGTGTAACTATCCGAAAATAAATTCATTTA
+GAAAATCGAGCCCGTAAATCGACGTTACGAAGAATTACTGTAGTTTTCGC
+TACGAGATATTTTGCGCGTCAAATATGTTGAGCAATACGCATTTTAAGAA
+TTTACTGTTATCGTAATAGTTCAAATTTTTCGAGATAATAGTCTTCCAAA
+AAACTATTGTTTAAGGTTTTATTTTTTCCGTAATCTAAATTGATTATCAC
+TAGACACTGTTCATTAATCATTCAGAACTTGTATAATCCATCTCGGTTAA
+ATTGTTGGTGAGACAAAGTGTAATCTGTTCTAGTTGGGTCACACGATCCC
+TTTTCCACTCAATCGCTTACCCACTCAACACTATAGACTAGACACTCACA
+CAGGAAATAGTATTGTTTACCTGTTTTCTTTTGGACACTGTTTATAACTT
+TTCCCTCTCCGTTTCTCTACGTTTAAATTTGTCAAAAATTAATAATTTTC
+TTACTTCCACATTCAATACTCATTTAATGACCGGTATTTGAAAATATTTT
+AATTTTTTAATCTTTAGTTATTACAGGAACAGTAAACTCTGGGAATTCGT
+ATTGCACAACATATTTGACGCGCAAAATATCACGTTAGCTGGCATAATAT
+TAGGCATATATTGTTTCTACAATCTTGTAATGTATAACTGACTAACATCT
+TTGAAATAAGTTTGTAAAACTTGTGAGTTGGAAAACATTGTGCATGGATG
+TCGTGTTTCGCGCACGCGCTAGAGTAGTCATAAAAAGATTACTGTAGTTT
+TCGCTACGAGATATTTTGCGCGTCAAATATGTTGTGCAGTATGCATTCTC
+AGAATTTTGTGTTCACGTAATAAATTAAATTGTTAAAAGATATAATAAAA
+GTTAAAAGATATAACAGATTTTTTCTCACTTCCCTAATATGTTTAATAAT
+CAATCATTTTAAATTGTGCCGAAAATTTTCCGTTTTCCAATTGTTCGGAA
+TTTTTTCGGTTTTGCTCGAAAAAACCAAAAAGCAAATTTTTATAAATTTC
+CCTGGTGTTCAAAATTTTCCCGCAATTTTTACCTATTTTATTTTCAAAAT
+ATTTATTTATTTCAGTTCCCCCAAGTCAAACCGTTCGATGTTGTAGAAAT
+GGAGATAATTCCGCTGCATTACGGAGCACAAGTTGGGATTTATGACGAGG
+ATCATGAGGTTGGTAGATTTTAATTTGTTTTTTAAATCGTGGCCTAGCAC
+ATTCTAGGCCACAGGTAGTGACGTCACTCTGAACATTTTCAATATATGTA
+AATTTTAAATTCAAACTACTTAAAACTCGGAAATCACTTTTTCCGTCAGA
+TACACAGAAATAAACTAGTTTTACCTTTTAAAAAACTAAAACCATTGAAC
+TTTTCACAAATGTTCTTTGAAACTTGAGATAATCTGCAAATCCCAAACTA
+TTAAAAACTGAAAAAGGTAGCCTAGAAAATGAAAATTTTCAATAGTTTTT
+TCAAGTTCAAAGAAAAAAAATTGAATTTTTAAATTGTTTTTTTTCGCTAC
+AAGTCAAAATTATATTATATTTATTAGTTTTTTTCAATTTAAGAACATTA
+CTAAAATTAGTGCATATTTAAAAAAAATGTTTGTTTCGGAGAAAACAACT
+ATTAGTAATTGCACTGCAATCATCAGATTAGTGAGGAATTTAGTTCTATT
+TTTTTCTTTTTTTTCTGTTTCAAAGTCGTTTTTTCATGAAAAATAGACCT
+TCGAGCTACTGGTTTTTTGAGAAATATTATTTCAATTTTCAATTTCATGA
+TGAACAACATTTTTGGTAACACATTTAATTCTAGTAGAATATTATCCACT
+TTTTCTCTAATTTTTCAAAATTTATTCCTAAGTTTTTCTGATCAATGAAG
+AACTACCTTTTTACGACAATATTGCCTTCAATTTTTTCTCTCTGAAAATT
+CGAAATTTATCTGAATCAATGGTGCCGGTTTTCTTATTTCTGAATAACGA
+AATAGATTTTTTATTTATTTTTCAACAATTCCCGGAAATTTCTCTATTGT
+TAAAAACAAATGAAGTGAAAATCGATTTTTTTACTTCGAAAGTTTAACAT
+GAAATTCGATAAATTTAATCTATGATCTTTCAAGCTCCGCGAGTTTGAGG
+CGGGATGTTGATAATTAGAGATATGCCGGGGGAGAACACTACTCTCCAAT
+TATATTTCGGTTGCTCGAGAAATATTTTTAATGATAAATACTGGATACTA
+GATTCTATAGAAAACTAATTTATTTCAATAAATTTATTATTATTCAGGAG
+AATTATATTTTCTTGCTCGAAAGAAAATAAATAATCAAAAACCGACGCAT
+TTTCCTGAATTTATAGTTATTCAGAAGAATATAGATTTTTATTTTCAAAT
+TCTGAGAATTCAGAAAACATGGCTATTTGCCGGCCTAGAAAATAGAACAA
+CTAGGCCACCGATCATTTTTGTTTTGCCGTTGTCAGGCTTCTGGCCTAAC
+TTTCTCTATCTTAAAAGATTCCCAAATTCAAACTACTGGCTTTCCAAAAC
+CTTCAAATTGTGGAATGAACTTGTGATTCCAAAGATCTGATGTCAAGAAT
+TCAGTCCATAGTTCATATACTCCAACAACACTTTTGGAATTTTAAATCTT
+CATGGTTTTCAAAAAGAATCCACCAAATTATTTAGCAACGGGGTTTTCCC
+TTCTAAACAATTGTGTGACACAAATCATAATCTCCGTCACTTTGTACAAT
+TTTTCTAGTTTTGGTGATTTCCCCTCATGAGCTCAACGCGGCGGAGTAGA
+TCTTCCATGCAGGCGTTAAAACGCCTGCCTGCCTGACTTTAAGGCGGCCT
+CCGCCTGCCTAACGCTTCAGTCCTAGTCTTGTGCTAAACCATACATGAAC
+TATTTTTCTAATTCTTAATTTGGTTCTCATAAAATTGATAAAAATTAGGA
+AAATTTGAAATCTGAAATTTCAAGTAAAAATGGGCGGCAAACTTTGTATA
+AAAAAAAAAAGAAAGCTCGGCCACCAATTTTTCAAAGTTTCTTACCGCTC
+TCTGTCTTGCCTCGGGCAAGCCCTAAAACTTTAGAAAACATCCCCGAACA
+AAAAAGTAATAAATCCTTCAAATGTGGGAGATGCCCCGTGTATATGTCAC
+CTGTCGACTCGTCGAAAACGTTTGTGCCACCCGGCTCTTTACCTCGTCTC
+CTCTTACTCATCATTTTACTGCCCCCGTTGCTTTCCGGCTAATGAGGTTC
+TTAGGGCGTAGGACGCCATTGATTTGTGCTCTTTTCAGGCAAAATTTTAG
+ATTTTATTTCTCTGATTTCACTCAATTATCAGACAATCTAAGTTTTTTGA
+CATGTTCAATGCTGGAAGCAATTTTCGATTTTTTTATCGACCATGGCCTA
+AAATTACGGGTCAATTTCCTGAAACGGACGAACATTTTTGAAAGCAAAAC
+AGTTTGTAGAGTTTCGCTAAAATTTCTGATTTTTATCGAAAAAATCGGGC
+ACACCAAACAAAAGTTCGTTTGTGTCAGGACCTTGACGGTACGCAATTTT
+CGGACAAACCACGTGTGGCTGATTCAAAAATGTCAACTAAATTGACATCT
+TGAAAACATTTTTTTCACCTGAAAACCACTAACAGTGTCAGGTTAATCCG
+ATTCAAGCGCTATTTTTATGAACTTTCCTGAAAGTTTAATTCCACACGTT
+GTGAGGGAATTTGACACATTTTTAGAAAACCTGATCTCACGGTTAATTTT
+TAAACACTTCGAGGGCCCAGAAATCCTAGTTTTTTTTCTGGTTATTCATA
+GTTTTTCTAGAATTTAATTTCACATCTACATTTCTAAACAAAACTTTTGA
+AGGTCCTTGTAATTCTTCTCTAGTTTTTTATTGTCAAATTAAGTTTTCTC
+CAAATTAGGAAGAAGCGATAATTGCGGGTTTTGTGAGGGAAGTTTGTCGT
+CGGTCCATTTGTTTTGAAATGAGAATCGGAACGATTTCCTGTCTCCCGTA
+GAAACCAATTAAACGAAAACTTTTTTTTTTCATTTCGTTCATTTTGCATG
+CTTGCTAGCCTCGTCTATTGGAATTCTTTTGTACTATGATTCTATTCTAG
+TTGTGTCTGCATTAAAAAAATCGATTTTTTTGTTGAGTATATTTATTTTT
+CAAACAAGCCGAAAAAATAGATCAAAACTGAAAATTTTATAAGAAAAATT
+TCAGTTTAAATCTAGTTTTTTTTTCAATTGGCCAACTTATAATTTATATA
+TACTCTCAAAATCAAAAAAAAATGCACATTCTATATTACCCACAAACATC
+GAAAATCCGCTATTCCCTCAATTATAAAAAATGTGAGAAAATCCTCGATT
+CTTGGTTGCTATGAGACAGATTTCAGATTTTTCACCGGATAAACAAGACG
+TTATCATTACTTTTCAGTAATGCGCGTTTATTTTTCTATTCCATTTTTCG
+AATTTTGAGATGTTGTATTATTTAGAGAGCACGAAATTCTAAGAATGCGT
+ATTGCGCAACATATTTGAGGCACAAAATATCTCACAGCGAAAACTACAGT
+AATCCTTTAAATGGCTACTGTAGCGCTTGTGTCGATTTATGTAAATCATA
+TATTCGTCGATATAATATTGAGCGAAAATTAAGAAAATAATACGAAAAGC
+GAAAAATTAATATCGAAAATCGAGATTCCGTAAATCGACACAAGCGCTAC
+AGTAGTCATGTAAAGAATTACTGTAGTTTTTGCTACGAGATATTTTGCGC
+GTCTAATATGTTGTGCAATACGCATTCTTAGAGTTTTGTGCCTCCCGTAA
+TATTATGTACAATGCGTATTTCCTCTGCATGCAAGACTAATTTCCGATTG
+GTCTGTAGAGGTGCAGTTGGCTGGCTGACTTTTAATACTTATGTTCCTTT
+AAATTTTCAAGTACGATTAGGAACCCTTTCTCTCAGAATTTCACTAGTGT
+ACCTTAATGTTTGTCTTTTGCTACCTGAGACGATCATCAAGTCTTTTCTT
+TTGTTTGTATTAGATTTCGCAGTAAAATTGTGAAAAAAATTGCAAAAAAT
+TGAGAGCAAGAGCAGAAATGTGCACTTCTCGTTGTACCACGATTTTTCGT
+TTTCCCACTAAATACCTATACGTATAGGATTATCCAAAGATGATCCCGGG
+GATCACCAGTTCTTAGTTTCCTTATCAATTTTATATTACTCGTATGCCTT
+CCTCGTTTTTTTTTCTAAAGCCATGAAAATCATAGGTATCGCCTCAGCGG
+GTCGTAGAAGGAGCACAATGTACTCGAGCTCGTCACGAAGACCGTTTCGA
+CGGCTGGTTCCGCTTAAAATGGTTAGAGAACTGGGTCTTGATGCGATCCT
+AACAAATTTTTTGAATCTCTAAATAGTCCCTATAGATCATGTAATAATAT
+AGGTTGAACGTTTTACAGAATAAAGTTTTACAATAAACTTTATAGCATGG
+GTGTGTGGCAAATTTGCCGGACTTGCCGTTTTCCGAGATCGGCAAATTTG
+CCGAGTTTGCTGCACACATGAAAAATTTTTAATTAAGATTTTGTGCAAAA
+ACTAATGTAGCCCCTGGTTTACACCTTTTTACGATATTCTGAGTACATTC
+GAAAAGGATGTTTTAAATAGATTGAATATCAAATCAAAAAAGAAAGTTGC
+ATGAGTATTATATCTAAAAACTTTTAAAGAACACATTTTCAGGCACAAGG
+CCGAACGGCAACCGACTACGCGGGTCAGGACTACGATGAATGTTATGATA
+GGTTAGTTTCTTTTTCTATTATTTCATTCAGAATATTACGAATTAATGCT
+TAAAAAATTTTCAAATTAATTTTCAAATCAACCGCCTTAGCTCCACCCAG
+CTCTCTAGATCGCAACCCGCAATAAAGCCCATAAATCAGTGGGCAGCTGC
+TGCTGCTCCGTAGTGGATCAGTCTGTCGTCTCTCCGATCAGTGCGCTCTC
+GATGATACTCTCACATTTGACCTTTCTCGCTTTTTGTAAACTATGTGCTG
+GACACGTTGAAAGTAGTATCAATTGCACTTTTCTGGGTAGTTACCGATAA
+AATTGCCCAGATGGAAGAGTTTTCCATAACAATTTCTCTTCCATTTTCAT
+CTATCAGCTCTGTGGCCCCGCTCATTAGTGTTTCTCTAGCCGATGCTGTT
+CCAGGTTCCCATGGCAATGTGTACATGTGTGCCTAAAGTGAGCCAAAATG
+CTCTTTGAATTATTCATTCATCCTATGTTTTTTATTCGTCCTCACGTGAC
+CTGCACCACACTGCGCATTAAATATTAATTGGCACTGAAGAGAGCCGCCG
+CTCGGGCAAATGTTTAAATTTTAAATTTAATTGATTTATACATATTTGAA
+AAATGAGACACTATGTTATTTTCGCCGAATTCGTTCTCTGAGCATTGCGT
+TCATATCTTTGCACCTATATGAACAATTAAAATAATTTGTGTGTCCGGTA
+ACGAAAAACCCGAAATAAGTCTTGCCTATACAGGAGTTTGTGGAAAGTTT
+TCAAAATTTTTAATGCAAACAACGAAGGAAATTGGAGACGTAATACGATC
+ACTAGCAATCTGAATTTCTACTTTCAAAACGTTTTTTTCATAAGAAACTC
+CATTATCCAAAATCCGGCCACCTTGCTAATCCTGAGTCCATAATAGGCAT
+TGCTAAGGCAAATCTAGGGCTTTTGGCCGATAAAAGACTTTTTGATAATA
+ATTTCCAAGCTTAAACCTTATTCATATTACTTTTAGTAATCCTATAAGTT
+TTGTTTGCAGTGGTTCAGAATTGCCGAACATTCCAAGTTTTTTGATAAAG
+GTTTTACATATATGTTGAGCTTAAAAAATAAACTCAAAAAAATTAACAAT
+TAGTTCATACGTTATTAATTTCAACGAGTTTTAGTGTAAATATATATGTG
+GTCCTCTATATATTTTCCGTATTATTATTATTATTGATTCGCTCCAAAGC
+TTTAATTTCAGTCTCAAGACTATACTGCTCAACTGTGTTTATAGTAGTAT
+TTTCAAACGAACAAAAAGTGACAATACAGTATACTTTAAACTAAAAAAAA
+CTTTGTCGATGAAAGTCTATCGATCAAACTAGCGAAATCCGCCCGTTTAA
+TCCGTTTTCCCGCCACCATCACTTATTGTGTTTTCATAGAGCTTTATTTG
+ACGGAATTTCCTTTCTTCTGATTTTTCATATTTAACCAAAACTTACTTGA
+AAGAATCTTAAAAGGGATTTTTACAACTCTCTGGATCAGATTTTTCGAAT
+TGTTTCATTCGCAAAAGAAGAGCGACTCACTGCTATAAATGCAACATTCA
+CCACACTATCTCCACAATTTCATCTATTAATTCATACAATGACACTACAA
+TAATCCCCACTTGCTCAGAATTTGTCTCTCCCGCGGGGGACAAATTGGAA
+TCAATCATTCTGTCGGTCGACCATTGAACCACCACCACACAATATGGTTC
+AGCGGGGGGAGGTCCAGTTTTATTGTTATTACGTATACTGCTAGGGGAAC
+CCAATTTTCGGACCCCGCGCGGAATATTCAAATTGGAAAGAGTGTGTGTG
+CAAAAACTTTGTCCATCTTGTGTCCAGCAGACCAGCCAGCAGCTTCTCAA
+TTTCCGCTTCAACTTTCTCCACTTTCCCATGGGACAAACCTTTTGTCTTT
+CTTCTGGCTTCTCCTCTTACTTCTTATTCTTCTTCGTTGCCCAAATTGTG
+CTGGAAGAACTAGAGATGCTGAAAAGAAATAGGAAAAGAGCACGAAGACA
+ATATTTATGTTTTGTTTTCCATGGTTCGCCTCGAGTATTTGATTAGGCTT
+CTCCTTGTTGTCTTCACTCGACGTCGTGTTCTCTATTTTATGTCCACTCT
+TGAATTCCTGGAGTTTTCAGTGCACGCATTTGTTGAGCTGTAAGAAAGCT
+GCAGGAGTTTCCCAGAATTTGATCGATTTACGGAGCGGAGTGTCGTACTA
+CTTATTTCCGGATTATAAAATTCTGAGAATGCGTATTGCACACCATATTT
+GACGCGCAAATTATCTCATAGCGAAAACTACAGTAATTTTTACGTTTCGA
+GAATCGAGCCCCCCTAAATCTACACAAGAGCTACAGTAGTAATTTAAAGA
+ATTACATTTCCGAACCTTTCTCATTTTTCAACAATTTTTTAACTTGCCTA
+GCGTAGCCGAAAATTAGCGGTAATCGCTTCAAGACCCAAAACAAGCCAAT
+TTCATCAAATTTCAAGTAGAATTTTGTGAAAACAACCGTCACTACCATTC
+TGATGACCCTTTACTTCGACCGCCCAGTTCGTTAAACATTTTTGAATTTT
+GTTCACCTGTCTGCCACCACATATCTTTCTTCATCAAAATTCAACGTGCT
+GCGATCATCATCTTCATCTCTGTCTCTTCATCTCGCCCAAATTCATTTCC
+GTCACTGCGTCTCGTACTGATTTTTTTTCATTTGTCTCCAATCATTTAGA
+GGCCAAAAGACCTCCTCTCAATTTTTTTCTGTCTGTCATTGACCCCTCAG
+TTGCGAACCGATTCAGAGTTTACATAAACAAGCTCGCTTTGTATATAATG
+TTGAGTGAGCGAGAGAGTGAAAGAGAGAAGACGCAGGAAGCTAAGCGTTT
+CCTTTGTTTCAAGCTCTGTCAAATTGTCAATTTTCTAGCTAGAAGATTCT
+TATGAAGTTTTGAACATTCTAGATTTAGTTTGTTACCTACAACAGGTGAA
+TTTGTCTTTCTTGTCCAGAGATAAAACTTATCGTGGCCTTTTCCGAAATA
+GTATCAGATTTCCTTTGTACAAGGGCTTTCGTGAGGCGGTAAATCGCCTG
+CCTGACTTTAAGGTGACCTCCGCCTGCCTCTCGCCTCAATACGTTATGCT
+AAAACAAACGTGAACTTTTAAAAAAATTTAATTTTCAACAAATTGATAAA
+AATTTAAAAAATTTGAAATTTACCTGCCTACCATAGAAGCCCTACCTTGT
+TCCACTATTGATGCGATTCATTCTATTACAAATCAATGTAACGAACTCCG
+AAGTTTGATAGCCCGAGGCGTTTTCCTTGTTAATTTGATATCGATTATCA
+GTTTGACCAACCAAACACCATCGATTTGGCTTGATTTTCAAGGAATTTAT
+AGAATTTCGTAGAGTTTTGGACTATGTTTTGCATTTACGTTGAATGGAGA
+GAATTATATTTGAATAATTGAATAACTTGTTAATGGTTCAAGGATTACCC
+GTTCCGAAGTCTAGAAATGCCCTGGCGATGCTCCCGTCGAGAACTGTAAC
+CGATAATCAATCAATATTGCGGGTATTAATTGGCTAATATTCATAATCCT
+GAAAAGTTATTTGAATAACGGCAAACTCCCAAGAAACATACCATTTCCGA
+GGTGTATGAGAATTTTAACAAGACCTTAGGGTACATAAGCCTATCAGTTT
+GAAAAACAATGTCGGAATTTGTGCTTCCATGGTAGACAGGCGCGGTTTCA
+GGGTCTGAAGCTTGCCTGAAGGCCAGGCAGACAGGCGTTTTAATTCCTAC
+ATGGAAGCCCTAGAATACAGCATATACGGTACCTAAGCCAATTATCAAAT
+TTTACTTTTAAAAATTCATTCCACAGGTGTTCCTGTTCTGCTGCATCATC
+GTCACACAGACACTTACACGCGCCTTTTCACTTCTCATTTCCCACTTTTT
+CTTCGTTTTTCTCGCTTTTTCTTCTTCTCGACACGAAGAAGTAGGATAGA
+TCTAGAGACGTCGAAAGCCATAATTGTTTCCGTCGGCGTCTCCACGCGCA
+CTCGTACTGTCTACAAGTGCCACACACACACTTGAAGAAAATAGAGAGAG
+GTGCAGGAGGAAAAGGAGGGGACGACTTCTGAAAGTGTCGATAACTACCT
+CCTATTTGAGTAAAGAGTGCAAGAAATATATGTGCGTGTGTGTCTAATGA
+GAGGGTCTTGGAGCGATTTTTAAGCATGTACAGGCATGAATCAGGCGGCA
+GGTTCCAGCCAGGCTCTGAAACCGCGCCTGCATACCAGGGAAACCCAACG
+ATGGTTTTTCTTTGCCCGGTTGATCCCTTTCTTGGATAGTTTTAGTCTTC
+GTCCGTTTTTCATTCATACTCTTTTTGTAACTGTTCAAAAGTCTAGTTTC
+ATATAATCAGAAATTCGAGAAAAAGGATTTTTCGAGGCTCTGAAAAAAGA
+TCCCAGAAGATTGTGTCTAATTCTAATTCTCTACAGAAAATGCCCAAATC
+GAAAATTTTTCGACAGATCCTCGTATTTCGAAATTCTGGAACATTCGGCA
+AAGCTGAAAATGTCACAACTTGCCAAAATGAACATTTTCGGCAAATCGGC
+CAATAGCTGTATTTTTCAAACTTTCGGTAAACCGGCAGTTCGCCAAAAAA
+AATTCGGCCATGGTCTAGACTCTAGAGTTGGGCGGCAGACAATTATTTCG
+GGCAAACGCAAAAATTAAAAATGGAAATTGGTGTTCGGCAAATCGACAAT
+TCGCCGGAATTGAGAGTTTCCTGCAAATTCGGCAAACCGGCAATTTGCCG
+AAGGGCAACTTCTCCGAACTGACACCCCTTCCAAAAATCCGAAATTTTTT
+TAGCTTCACCCCCTTCCCTCCCTTCTCGTTTTCTAAAAACCGGACACACC
+TCTTACAATTATTACAAACACCACTACGTACGTATTAAACGTCTCTCGTA
+ATAAGTGGGGCGCCAAAATATAATGGTTTTTGTTGTGTTTAGTTAGCCTC
+CTCCTCTCTACTTCTCCACCATCATCAAATCTACCACCACAATAACATTA
+ATTCGATCATCAACTGACTACTTTTGTCTTTCAATGTGGATTTGTAGTTG
+TTGGTTATTTGAATTCTTAACTATATATCCATCCCTATGTTGAAAATTTG
+AAATTTTTGGTAAATTTGAAAGATACCAAGTTTATGTATATTATAATATA
+TTATAAAAATTTCCGGTAAATTGATATCCTGCAAACGGCAAACCGACAAT
+TTGCCGGAATTGAAAATTTCCGGCAAACCGCAATTTGCCGATAATAAATT
+TGCCTTTATTGATTCTAGGTTTCGAAAAATTACGTGTTCCGTTTTTTTTT
+TGAATATTAAAATAGGAATATCAGAATTTTTTATTTTTTATTCTGCAACT
+TTTCAAATTATGTTCAAATTTATTATAAAACTATCGTAAGTGTGAATTTG
+CAATTAATTTTCTTATTGCTAGGTATCAGTTTTACTAGGGCTGTCATGTA
+TGTACCAAAACGCCTACCGCGCCTTCTGTCTAGTGCGGTGCGGAACCCGA
+AAAGTGTCGGAATCATCTTTCGCAGTATGTGGTGCTGAAACCAAGCCTTT
+GAGTTCTCGCCATAGTGCGGCGAGAGGCCGGCATGAGGCGGGCAGGTAGG
+AGGCAGGCTTCAGGAACTGTGTCGCGTCTGCCTCCCAATCCCAGAATACT
+TTTTTTTTCAAAAAGTTGCAATGGAAATCAGATTTTCAAACGCAACCTGT
+CTTCCTCTTGTACTCAACTTTTACTTGATGATAGTCGATAAAGGTGTGAA
+CGCGGTGAGGTGTAACCGTGTGACAATACATCATTGTATTATTCTTTTTC
+GCAAAAAAAAAACATTCTTTTGGGTATTATATTCTACCAATGTATCTTTC
+ATTTTCTCGATTGATTTTTTCTCCGGCGAAAAGAAAACAAATTGAAAAAA
+AACGTCAAAACATAAACATTTGGAAAATATAAAGGTGGATATAAAAACGG
+TTTCTTTCTTCTGGAACATTCATTTTTAACCATTTTCCTACATATTTTCA
+CGCTAAGCCGGAGCAAAACAGAGACAGTCGAGACTGTCAAAACATGTAAA
+ATATACGTTTTTTGGTATACCTATTTATTAACAGGTGCTCCCTTTTCTCT
+AAAAGTTTAAATTTGTCGCGAAAAAATGCAAGAAATGTTTTTTTTCTAAA
+AACTAAAAACTCGATCAAAAATAATAATTGGGTATTTAAATATTCCGGAA
+TCTCCATTTTCTTCCCGTTCCTGCCCTTCCATTTTTTTCTTCCTGCACTT
+ACTCGAGTATTCATCCTCTTCTACTGCTGCCATAAAAGGTCTTCCGCTTC
+ACTGAAGCCTTCTGCACAGCAGCGTATCCTCCCGCTTCATATCTCGTTGC
+TGAACTCCATATAGCTTGTTATAGCTCAGTTTTAGACGGATTTAGGTTCG
+AATTTCTGTAGGGTCTCTAGGAGTACTGTAATAAGTGATGTGTCAAAAAT
+TTGGCCTAAACTGTCATTGCTATAGATTACGGTGATAGAAATTTGAATAT
+GTATGAAATAGTGAAAAATCAGTAGACTGAGCCTTACTCAAATTCACATC
+CGTTCGAGATATTTCTGAGTTCTGAATTTCTGTTGATTGCAATTGCCGTA
+ACTTATAGCAAGGAAAGAACAATTTGAAGCCGAATTTACGGCACAAAATT
+AGTTTTGGTGCTTCTAGAGCCTATTTTATAAAATATATACTTGACACGTG
+GCTTTTCAATATCACCATCTCAAGAAATTACCACAATCGTTTCAGGTGCG
+AACAAGAGTGTGGCGAGGAGGCGTGGCGAATCGCGTGCTGCTCACGAGTC
+GGGAAGATCGCCATCCTTGTCATGTCAATCATTGTATTATATCTTATCAT
+ATCAGGTTGGTTTAAATACATATTATTCAAATTTATCTGAGTTTACACAA
+TGAATTTTCAGCATTAACGCCCTCCGAAAGCACACACAAGACGGACCTCA
+ACGAGCCGCGGCCTGGTATTAATTTAACAAGGTGAGAATGTTGGGAACAT
+ATTACTATTGTAGGAAATTGCTCGATAATTCCACACTTATTGAGTTCACA
+ATTAATTTCTACTATATTAACTGTGTTTTTGGTAAAGAAGTATCACTTTT
+TCCCCTCCCAACTCCGATAATTCGGCATTCCTAGAGTTTTAACACAATGT
+TTTACGACATACTTATGAAGAGTTGATGCAAATCGCAAAAAAAAAACAGA
+AAAATAACTATTTTATGAATAGTATCATTATCGTATGGTGTCGTCAAAAT
+GTTTTGTTGTTTTAGTTTTTTTTTACTCGAAATTTTCTGAAAACACCGAA
+TTTCATATTGAATCAAATTTCTTGATAATTTATTAGACATTTCGATTTTA
+CAGAGCCAATCAAGTACTCACCGGATTATGTGATGCCTATGAGCGAGGAG
+ACGTTTCCGGAGACTCTTGTAATCGACTTTGCTATGATCGAAACTGGCTT
+GTCACTGACTTTTACGAAGGGCACAAGACTGTGGTCATAGTGAAAGATGG
+CGGACAGATTGCTGTCTATAAAAGCACAAAACCGTTTATGGATCAATTCG
+ACGAGCCGAAAGACCATCTGACGGATGCAGAGTTCTCGGATCGAGTAGTC
+GATATGGTGAATGATGAGCTGAGACTCGGATGGCCGAAACACTATCGACG
+GCATTTAATGGAGACTGTGTGGCCGACACTGTTACGGACCAAGGGAGAAG
+CCATGTCGAAAGCGGATCGACGATCCTTGTGGGCTTTGTTAAAGCAGCCT
+GAATTCATCCTGTTCCGAGTGTTACCGTTGACACGTGTCACGCCGAAGCT
+CATTGGGACGTGTGGACATATGTATCAGACTGAGTCACTGGTGGCGTTCA
+AGATGAAAGGGTATTATACGAATTTGAAGGTGGGGATTTTTTTTTAACTT
+GATTTTAAAAAAAAAATTTTCTCAATCCAAATTTACAGGCAAAAATCTTG
+GTGCATGTCATGGGAACCCTGAAGCTCTTATACGAATTTCTCGACGAACC
+CCTTCAATGGTGTGATGTTCGATTTGATAATCTCGGGTTATCAGCAGATT
+ATCCGAAAAGGTAGGTCTGCCTGTTTTTTTATTTGATTTTTTTTTCCGAA
+AAAATCTACATTTTCAATTATTCGAAACGTAATTCGAATAAAAGTTATTA
+ATGATTTTTTAAACAAAAAAATTGATGATAATCCAACCGGAAACTCAAAT
+TTTGAAAACCCCTAAAAATCCAAATTTCTCAATTTTTCTGCAGATTCGCT
+CTAATGGACGGTGACATGGTGTACACGAAATCGAAATTGGATTCTCTCCT
+AAAAGGACGTCCGTGTGAAAGTGATAATGATTGTAAAATTGGAGACTGTG
+AGGCGAGATGCACTTCTAATATGGTGTGCTCGTCGAGGAGTAACGGGAAT
+TTGGAGGTAAGCTTGAAAGTTGAAAAAGTTTGGAAAAATTGTGAAAAATC
+AATAAAATCGGCAAAAAACGAGCTTTTTTCCAGATGGCCGAATTTTTCAT
+AGTTTGCAAAAGTTCGTCCACCTGTGAAAAATTGCTAAAAAAGCAACAGC
+ATTGATGAATATTCATAAAAAACCAATAAATTCGACAAAAACCTTTTTGA
+TTTTTCCAAAAATCGAAAATCACATTCTGATGTTCAAATTGAATTTTCAA
+AAAAAATATAGAAATTTCCTAAAAGTTTTAATTCTCAAAAAACGAACGAC
+TGACAAAAAATTTTTAAAAAAGTGAATTTTCCGAATTTTTTCTAAAGAAA
+AACTGAAAATTTGAGAATTTTCAGTCAGAAATGTGATTTTTTTTTTGATT
+GAAAGGAGTTTATTTTGTAGAATTTAACTTCCACTATCAGAAAAAAATTT
+ACCTATTTACTTTGTAATAGGAAAAAAGTTGTGAAATTGTTAGGAAAATT
+TTTTTCAACTTTACAATTTCCCGGACAGGCCTGTAGTTCCTTTTTTTCAA
+AACGTAAAAGAAAAAATTAATTAAAAAGTTCAAACTCCTAGAATTTATAC
+ATTTATTTTGCATTCTAAAAAACAAAGTTTTTCTTGATTTTTTTGTGTAA
+AAATTGAAAAAAAATCCAAATTTTGTAGGTCTTCTGCGATAAACTGGTCA
+ACAAACTGTTCGCAAATCAATGGTCCAAAAATAATAAATATTTGGTCGCA
+TGCCGGGATACAGGACGAAATATCACAACTCGACTCAACGAATTACGGTT
+AACATGGTCATGGAATCTGCCGGATGTTTAAAGGAATCTAGCTCAATTCT
+TTCTTTTTTTTTCTTCTACTCCATGTGTCAAAAAATCCCCGTGTCTTATA
+ATTTTCTGGTGCTTTTTTCCATATTTTCCTTTTTTTGTGTTCTGGCTCAT
+TTTTCCATGGCTCACAGAGCCCGAAAGCTTAGGATTTTGAAATTTTATTC
+GTTTTTTTCTCATAATTCTGTCATCATTTTTTGCTCTGCATCATCATCAT
+CATCGTCAACATCATCGCGTTTTATTATGGGTTCATGTATTATTACACTT
+TCCTCGAAAAAAAATTTTGACGAACGTGTAATATGTTTCACCTTGTCTCA
+TTTGTACCTCGTTCATTGTTACGGGTTTGAAGTTTTAAAACTCTGAATTT
+ATATGAAGAATTTTAATTTAAAAAAAAACTTTGTTTCCTTTTTTGAATTT
+TTACAGACAAATTTTTGGCTTGAAAACTGAAAAACCCTGACTAAACTTAC
+TATTTATGTGTTGGGTATCAACGTGTATTGACCCACGACGTGGCTAAGAA
+GATCGTACAACGTGAACTCTATGAACTAACTTATTTATTCCTTAGTTTAG
+TAATGTAATAAACTACTCGTCTTCTCCTCCTCGTCTCGCCTTCGAATACA
+CAACATTATGAAAAGAGTTTTTCTTAAGATAAAAAATGTTCTAAAAAATC
+GATGGCCGAGTTTCCTATTTACGCGGCCACAAGACCAGTAAAAAAGTGTT
+AACACAAGTGCGAAAACTAGAACATTTATTTTCAAATTTCACCCGATTTC
+TACAAAAAATCAACAAAAAAGTCACAAAATTTAAAATATGAACATAATAA
+TCAATATCCCGCTGGCGCTGACTCCTCCCCTTTTCGGAAATCACTGTTCG
+CATAGATTTGGCCGTCGGAAAGTCGTTCGGCGGCGGTGACAACTGTCAAA
+TTGTTCACTGCCTTCATTACGTGACCACGATCGATCAGGGATTTCACGTA
+GGCTTTCGGGAAGTTTGGCTCGTACCACGTGTAATTTGGCTAAAAAATAA
+GGAAATTGGGAAAGGTTTTGATTTTATTGATTGAAAAATATTTCATGTGA
+AAGTCGAAAATTGATTGAAAATTAAATTCAGAAGTTTTTTTTCTGAAAAT
+TATTGATTTTTATTTTTAAAAAATCAACTTTTTGACAATTATCGATTTTT
+CCAACAAAAAAAAAATCAAATTTCGCGTGTAATTCTCTACCTGTAACTGA
+TTGTGCATCCTTGGAGCATCAACAGCTTGTTTAACATCTGCTTTCAGCCA
+TAACGCATGCAGTGCAACTCCAGCAACACCCGAAATAATGGTGGATCCAC
+CGGCTCCGCCGACCGCCATAAGCTCCGCCCCTTTTGTGTTAAAGATCACT
+AATGGACTTTGACTACTCATGGGGCGTTTTCCAGGGCGAATGAAATTGGC
+GGGAGACGGTGGGAAACCGAAGAAATTCGGATGACCGGGAGTGGAAAAGT
+CGTCCATTTCGTTATTCCAGAGAATTCCCGTCGATTCGGAGGATACTAGG
+GCACCCAGGCTGGAAGAATTTGAGATGGTGGAAGAGTTTTTTTGGCGGTG
+GCCTAGAAAATGTCTTCATATCCGAAAAAGTCAAAGTGATGGCCTAGAAA
+TTTAAGTTTGTGGCCTATAAACTTGAACTGATGGCCTAAAAATTGAACGT
+CGTCCTAAAAATGTTTTTAACTGATGGCCTAGAATTGAAAGGTGATGGCC
+TCCAAATTTCAGGTGGGCGTATATAAACTTTGGTTGATGGTCTAGAAATT
+ATACACGTGGCCCAGATTATGAAATCACTTCGGTATAAAATCCAGGTGGT
+AAACAATTTACTATTAAGACTGCCTAAAATCATCCCCTGGCCTAATTAGT
+TTAAAATTTTTGGTGACGACCTCGAACTTGTTCATTTTTATCAACTGCAG
+TTGCTTGTCGACTGAGGACTAACTTCTCACTTGCTGGCCGAGTTTTCGAA
+GTTCGGCCACCAAAAATTTCCTTTAAAAAAGCCAAACTCACTATAAGTTA
+ATGGTAGACGTAACCGAAACTGCATTGCCGTCTGCATCGATAATCGATAC
+ATGAGTTGTTCCATGATCCTGCGGTGGTGCTTCAAACGATCCTCCATAGT
+AATCATCAGGATGCGTCGTGTCTGTGATCTTCGACCTAACCCAATCCGCC
+CACTCTTTTGACGTAATATTTTTGGCGATTTCCGTGGCGTTTGCCACGAA
+TTGCGGGTCGCCAAGCCAGCTTCTAGCCGCATAACTAAATTTGCTAGATT
+CCAGAAAATGATGGTATAACGTTGCGATTTCGTTGAACGACTTCATGTTA
+TATTCGAAGCCATCCATCACGTTAAGTATTGCCTGAGCCACCGCTGAGCC
+CGAGGGAGGCGGCGGGCCGCAGACTCCGCGCCCGTTTTTCAGCTTTGTGT
+AGATCACATTTTTTGAGTCGTGGACTATTGATTTGTAATTTTTAAAGTCC
+TGAAGCCGGATGATCCCACCGTTGGCTTCGAACTCTTTGGCGAGTTGCTC
+GGCGAGCCGACCTGTATAAAAGTCGGCGATGGGATCTGTGGAGTTTGCGA
+GTAGCCGGAATGTTTCTAGAAGGTTTTGGCGGGTTTTTATCTGCTCTCCT
+GGTTGGAAGACACGCTGAGTTTCGGGGTTGATGAAGTTTTTCATGGTGGG
+CTCCGCGCGGATTTGGTGCTCGTTTTGGTTGAGAGCTTTTGCAAGGGCAT
+GGGACGTTGGGTAGCCTGGAATTTTTTAGGATGGCCTAGAAACATGAACC
+GATAACATAGTTACTTATTTTGTGACCTCGAAATTTTCATGATGGCTTAG
+AAATTTTTATGATGGCCTAGAATTTTTATGGTGACCTAGAAATTTTTTGA
+TGGTCTAGAAATTTTTAGTAATGTAATAAACTACTCGTCTTCTCCTCCTG
+AAAAAATTTGGGCCCGTCTCCCTTCGTGGTGAGACCCATCGTGGCGAGAC
+CCATCGTGGCGAGACCCATCGTGACGAGACCCATCGTGACGAGGCCTATC
+GTGGTGAGACCCATCGTGGCGAGACCCTCCGTTGAGAGACCCATCGTGAT
+GAGACCCATCGTGGTGAGACACGCCGTGGTGAGACTTATTGTGATACCCA
+TCTTAACGTACACAGTAATTGGAGAAACTTTTAAACTGATTTTTACAAAA
+AGTTCAACATTTAACTTACCAAGAGCTCAATATTCCGTTGCCTCGCTTTT
+TGTTGCCCTCAGGGATTATTGTTCTGTTGCCTCCATTTCCGTTACCCCTG
+TTGTGTTGCCTTCGAGCAGCGTTGAATCCGTTGCCCCCCCCCTTTTTCGT
+TGTCCCCGGGGAATATTAAATCCGTTGCCCCCGTTATCCGTTACCCCTAG
+GGATTGTTGGCCGGTCTAAAAACGGCCACCAGAAAAGTTTTTGAGCATCA
+AAAATGTTCTACGCCGTTAGGAGTTTTTTAGGCCAACAGAAATATTCTAG
+GCTCGCAGAAAAAGTGCCCACCTTCAGCCAACAAATCAATAGTTGGTTTC
+AACAACTGTCTCCACTCGACTTTTCCACTTCCGAATCTCTCGAATTCAGT
+CCGGAGGCCGTGAAGCTCTCCGGGCACCGCAATCGCCTTCCATCCGATTC
+TCGACTGATTCCATTTGTCACGGTACATTTCCTCTGTTGCGGCGAGCGGA
+GCAATCTCCCGAGCATCGATTACCGTACACTCTTTTGTCGTTCTGGAAGA
+ATTTTAGAGGTTTCTAAGTCATTGAAAATATTTTTAGGCCACGGCAGAAG
+TTTAAAGGCCACACGCGCTTCTGGCTTTCCTCATATTTTGAAATGGAAGA
+GTTTGCCGAGTTAGCCCGTTTGGACTAGGCCACGACCGGGGTAAATTTAC
+GGAGCGTCGTGTAGACGATTGTCAATGGAGCGCGAGAAAAACGCTTTGAC
+GAAGGCCAGAAACCAGTGAGGCCACAATGTGATGTTTGCAAAAATGTTTT
+TAATGGCCTAGGAAAATCATTCTTTCTTCCAAAATTTTTCTTCTTTGTTT
+TCCTTTTCGATTATTGATTTTTAGTTGAAAAATCAATATTAATAATTATC
+TTTTTTTTTAATTATTGATGTTCCGCTCCAATTCGTGGCGAGACCAACAA
+CTCACGCATTATAAATAGTCATAAAATGTCCGCCGCCAATTCCGGCCGAA
+TGTGTATCCATTACACCGATACAGAAAAGTGCGGCGATTGCCGAATCCAC
+CGCATTTCCGCCTTTCAGCAAAATATTCCGACCGATTTCTGAGCAAATTT
+CGTTGTCGGCGGCGACGGCGGCTTTCGAATATTTTCCGAGTGGAGAAAGT
+GATGGTCCAGGCCAACGGGGTAGGCGGGCATTGTTCTGGAAACCTTGCCG
+AGTTTTATTTTTATCGGCCACGTAGCAAATCGGCCAGCCATGAACCGACT
+GCGGACTAGTTTTCACCCTCGTGGCCTAGCTTTCTAACAAACCTGCATTA
+GTAAATGAAAATACAATGAAGCGAATGCGACCGTTGAGATTAACAACGTG
+AATACGAGAACCGTTAAGCCGACCGCCGCGACTAAAGTACGGATTTTCAT
+GGGTTGCTCGGCCTCGATAAGCGGCTCAACTTCATCAAATGGTCCATATT
+CTGGCGGTAAATTATCATCGTCCGGAAACGTGTTATAGTATTGAACAGGA
+GGTGGGTTACTGCTGAAAAGTCGAGTTTTGCGCGTCAAATTTGATGTATT
+GAGTGGCATGATCACTATTATTACAAGACCGCGAAATTTTGAGAATGCGT
+ATTGCACAACATTTTTGACGCGCAGAATATCTCGTAGCGAAAACTACAGT
+AACTCTTTAAATCACTACGGTAAAGCTTGTGTCGATTTACGGGGTTTCGG
+TTTTTTCATTTTTTTTGTGTTTTTTAAAAAACAATTTATCGACTAATGAA
+TGATTTCCGTAAATCGACACAAACACTACAGTAGTCATTTAAAGAATTAT
+TGTAGTTTTTGCTACGAGATATTTTGCGCGTCGAATATGTTGCGCAATAC
+GCATTCTCAGAATTTTGTGTTGCCGTAATAATTCTGATTTAAAAATGGAA
+TTTTCAAAAATCAGAGGTTTCCCAAAAATTTGAATATTCCACAAAAAAGA
+TGAATCTGAAGAGTATTTTCAATTTTTTGAGAAAATAATCGATTTTCTGG
+ATTAAAAAATTTGAATTTATAGATTTCTAGATTCTAAAATTTGAATTTGT
+GCAATTTCAAACAAAAATGTATCGATTTTTATCGACTTTTCATAAAATTT
+AATTTAATTTTCGAAATTCCGAAAATATTGCCCGTTTTTCATATACCAAA
+AAAGTTGTATCAATTTTTTCAAAAAATTAAATTTTCATCGATAGTTGTTT
+TCAAAGCATCATGATTTTTTTGAAAGAATTTGCAAATGTGAGAACTACAG
+TACTCCCTTAAAGGCGCACGCTTGTTTTTATTTTTAAAAAATTGGTCGTT
+TCGAGACCTGGTACCGTATTTTCGCATTTGGGTAATATTTCCAGCATTAT
+AAATTTAAAAACAATGCACTTTTTAAATCTTGAATCCATATATATATTTT
+TTTCAGAAACTCATGCCGCCTCGTTTGGGTCTCGATTCGAATTTTTTTCA
+CAAACGTATAATATTTTCTCGAAAAACCCGCGAATTTTTAACATTATCGA
+TTTTTCTCTCACCTCGTCGATTGCCCTTCAGGAGTCATTATTCAGAATTG
+AGTATGAATTAAAAAATCATAGAAAAAGTCAAAGCGCTGTCAATTGGAAA
+TTTAGGACGAGAATGTCAAAATTGCAACTTTTCACGATAACGGAATTCTA
+TCGCAAAACTAGATAAGAGCTACAGTTTGCTGCGTGTAAGCGCGCTCCAA
+TGACAAACGAGAAGAGAAGAGAAGAGGGGGTAACCGCCAATAGCTCTCTT
+TATCGAGGATAGTCTTCAAGTGACAGAAGAGATATTCTGTGGTGGGAGAG
+AGTTGGGTGGAAGGGGGAACAATGAGGACTACGGAAGAATGACTTTTAGA
+TTTGGAGTATAGGAGAAAGTGGAGGTTTTGGCTGAAATTATTTTCAAAAA
+CTTTAACTGTAACAACTAACGAGTAGATTTGAAAATGAGGATAATATTCA
+ACACAACAGAAAAAAAGTCGATAGGTAACTAATAAAAATTAGAGAAAATG
+TGGCATCGGGGAGAAGTGGTGGAACAAAAGAAGAAACTGATGATGATGAT
+AGGAGGATAGCCGCGAAACAAGCGATTAACAGTGAACAAGATTCATTTCG
+GTGAAGATGGAGAAGATAACAGCAAAAAAAAAAACACAACAAAAGTCCTT
+ATTATTGCCCATTGAGAGTTTGTTGAAGGACACTGGTAAGGTGCTCGTCG
+ATTCCATCTTGCTGCGCGAATTGTGGGAACGATGCGTAGATTTGCTTCAG
+GATTGTGACAATTCTTTGCTTGGTTTGGTTGCCGCTATCGTCGTCGTTGA
+AAGCATCGTTGGCGATTGAGAGCAAGCCTGAAAAATACAAATAAAAATAA
+AATAAGTTACGGATTTTTTTAGATTAGAACTTACAAACAAGGAAGATTCT
+CGGAAGATTCTGATTTTCTGGTCCAAAAAGTGCGGCGTCTTGTTTATCAA
+ACAATTCGGCGAGACACGTGTAAATGTAGGGGCTTTCCTCGGTGTCTGAA
+TATGTTGGCAACCAGCTCAGGAACATCTCGACGACCTGGAAATAATATGG
+AACTTTTTTCTTGAAAAACTGAATTCTAAAACCAACCTTTCCGTAGGCTT
+CAGCAGGAAGTGGCACATTGCCGATGATTTTGGCAAATGCAGAAATCGCG
+TTTTCCGTGGCAACAGTGCTCTCCTCGGTGGCTCGGGCGTCCTCTCGTTG
+AATCATGGCGGCCAGTGGCTCCAAACAGCTCAAAATCTCGTTTCGGTAGT
+CGCTGATCTGGTGGTAGTTGATGGCCATAACTCCGAAACCGTAGCTCGCT
+GCTTGTCTCACTTCAGGATACTCATCTCCCAACAACTTGTACATTATTGG
+AATAAGCTTCGGGAAGCGAGTTGGCATATGTCCGACACCGAACTCGATGG
+CGTCATCGAGAAGGCACATTCCCCATTGTCTCTCGAAGTATTGTTTGGAT
+CCCTCGATGAGTTGAATGGCACAGTTGAACACGTTGATCATTCCCTCGAA
+GATAGTTCCCTTGAACTCCTTCATAAGAGAGTGAGTCAAATCAGAGATGG
+CTCCAAGGCATGAGGCCTCCAATTCCATGAAATAATCGAGCTCCTCCTTA
+GCTTCAGCATCATCGTCATCTTCATCTTCAACTGGACGATCGCTCATTCT
+CTTTCCGTAGTTTTCAAGTTGCTTGAGAAGCACCGAAATGATGAGTTGAA
+CCTCTTCCTCGGCGATTCCCTCGGTTTTCATAACCTCAATGCACGATCCG
+ATGGTCGTCATGAACGAGGCGAGAATCTCGACATCGTCCTCCTCCTCCAT
+AGAGGTCGTCAATGCCTTCAAGAACTCGCACCACAAACGACGCTTGTCAG
+CCAATCCTTGCTTCTCAACACAGGTCAACAAGCATGGCATGATTTCAGCG
+GAAGCCGTACGAACTCCGTCGTGAAGTCCGAAATCGAGATTCTTGATGGC
+GAGCTCGTAGACGTCGACGACGTATGGCATGAAAGCCTCCTTCATCTCCT
+TGGCGAACGCGACAAGCATATCGCAAGCAGTTGCCTTCTCCTCAAGACCG
+CTGGTGCGGATTCCGACAGTCTTTTCTCCTCCGATTCCGTGGTATTCAAC
+TCCTTCCTCGTTTTCGTGAACATCTTCGTCTGAAATTTATATATTTTTTT
+AACACGTAAAACTAAAAAACACTCACTGTTGAAGATATTGAAGTCTGGGC
+GGTAACGAGCGGCACGAAGAACTGGATCCATGACAACTGGGAGGAATGGT
+GCGAAATCGGCTCCAAGAATAGAGCAGAAACGAGTCCATGAGCTGATCAT
+GTAGCTGTATTGTGGATCATCGATAGCCAAATCCTTCATTCCGTCTCCGA
+GAAGGTTCAGGATCTCGATTGCAGTAGCGTGGAATTGTTCCTTTCCGACA
+GCATATCCGATGAGAGAGATGCATTCGATGGTCTTTCCTCTCAACTCCTT
+GAGCTCTCCGACGTTTTGAAGAATGTGAACGAGGTTCGGGATGAGGCGAG
+CATGATGTTCCTTGAAGAGCTCCTCGGCGGCTTCAGCGACGGAGGCGATG
+GCGGTGACGATGTTCTCAACGACAACCTGGTATCTCTTGTCTCCGAGACG
+ATTGAACACAGCGGAAAGCACATTTTCGAGTTTCTGAAGAATGAATGGAA
+GATATTGTCCAATGATGCTCTTTGGGCACTCCTCGGCAAAGTTGACAAGA
+GCCGAAGCGGCATGAGCACAGACACGTGGAACATCGGTTCTGTCAAGAGA
+CTCGAGAAGAGCTGGTATGACGGCGGCGTGGCACTTCTTCTGAAGAGTTG
+GAGCGAAGTCAGAAGACATTTGTCCGATGGCGTTGCAAGCCGCGTATTGA
+ACTCTTGGATGAGCATCATTGACGTAATTGGTGATATGAGCCATAATTTG
+CTCTATGTGTGGTTCCATAGATCTTTGGCACCCTTCACCGACGGCGGAGA
+ACGCGCGAAGAGCCGCGTGCTTCATCTTCCAGTCTTCGCTGGTCAAAAGC
+TTCTCGACAAGTGGAAGGAACACTGGGAGCATCACTTTTCCGTTGATGCA
+GCAAGCAACACGGTCGATGGCGCTTTCGGCGATGATTGGGATACTGAAAA
+ATAATTTAATTGAAGAAAAACTAAAAATTTATCCTTACTCTTCATAGTCT
+TCTTCCTCTTCGATCTCGTTGAGCCACTCATTGAGCACATCGTCATCCAT
+TTCGGTCATGCATGAAAGAAGAGTCTCGAGAATTGGTCCAAGAGCTCCTG
+GTGCGTATTTCTTGAGTCCTTTTGGTGCGGATTCCATGTACGAGCAAATA
+ACTTCGATGGCGTTCTGACGGACCATCTCGTTCTTTTCCTTGTTTCCAGC
+AATCTGAAATTTGAAAAAATGAAATTTTTAAATTGGGCCATTTAAATTAC
+TTACAGCAAGAGTGACTTGAAGAACCTGAGACATATGAGTGTTAAGGCAT
+TTTGGCAGAGAAGAGGCGAGCTCGGCGAACTCTCCGAGTGGTCCATCTGA
+ATCATCCTCGTCGCTGGTTTCATTGCAAACTTGAAGAACATTTGGAACAA
+GAGAGGTCATAAGCCTGACAACATCCTTCTCCTCATCATTATCAACAGCG
+AAAGCGATAACAGCACGGACGGCGGTGGCCTTGATTTGCAAATCCGGTGT
+AGCCATGCACTTTTCCAAGACAACTTTGAGGGTTGGAAGGAAGTGGGCCA
+GCCTGTTTCCAAAAATTATTGGGCATCCGCGAAGAATAAGCAGGGCTATG
+TAGTTTCCGGTAAGATCCTCGCTCTTCAAACAATGATCCATCAGCTCGAG
+GACTCCTCCCCATGTCATATCTCCAGAATCGTCGATGAGGTTTGAAGCGA
+TTTCAGAGATCAAATCAGCAATCTTCTTCTTAATCGAGAGTTCGGTCTCG
+TGAACTATCATCTCGAGAACTTTGGCGAGAATGCGCTGTTTGTTCTCCTC
+GTTCAGCGTTTCCCAAATCGCATCCCAGTCTCTGGCGAGAACTCGTCGCA
+GAAACACCAAAACTGTGGATCTGGCCTGAAAATCGAAAATTCATGGAATA
+TATAGGAATTTGAGTGAACTAACATCAGAATTATTCGTGTGGTGTGTGTA
+GGCCTCGAAAAGTGCAGCTACTTTGGTTGGTCCTTCAATCTTTTCATAGA
+CTTCTTCAGCTTGTTTTCGGATATCATTGTCTGCTGACTGCAGTTTTGTG
+ATGAGCTCAGTGAATTGATTGACGTCCATTGTAGGGAACCCTGAAAATCA
+GAATATGTGCTAAAAATTTCAAAATTGAGAAGGAAAAAGATGAAAGCGAG
+TCGGTTTTGCAGATAAACGCCTGGGGAATACGCGGAATCGCTGAGGAAAA
+TAGATTTTTAGTATAAAAATTGGCATTTTCAACAAAAAACCTATCGGAAA
+ATGTGAAAAATAGGCCAACAAATATTGAATTTTGGGACAAAAACGCCTCG
+AGTGCACGATTCTCAACGGAGCGCACTTGCTGCGTCACACGCACTTTAAA
+CTGTACACGGCGGGAAGTTCAAATTTTAAAAGGATTCACGTGATTTTCAC
+GACATTTACTGGTTTTTTCAGCGAGTTTTCGCAACTTTTCGGCGACAACC
+GATGATGATTTATGTTTGGAATATGATGATGGTAGCGTGTTGCGAAATAA
+AAAATCGATGGAATGAGTCAGCGAGAAACTAATATTTGCATAGAGAACTG
+TTTGCAATTTTGGCATTACATTGGCCAGTGCACTGACAAAAAAAGAAAAA
+AATAAACGGCAAAATCTCTAATACCTATTCCAGGCAACCAGTGTCTGGCG
+ACGATGGAGAGTAATTCTGAAAGAGACGCAGTTGAAAAGAGTGTGTTTTT
+CGCTTTTTTTTTCAGACAGAAGAGTAAAAAGAGTAAATACGTATCAGTAG
+TAAAAACAATGTGCGAGCTGGGAAATCAGTAATAATTAACTACTTGTGAT
+ACAAATTCCTCAAGGAATGAAGGAGAAAGTGTACTTTTTTTGAGACCCGA
+AGAACTCGGGGGATGTCCAATTGGGGGGATTACCAACTCGGGGGATTGGC
+CCCGCCCACAGAACCGTGGCTTGCAATACGCCCATTTCTGCAACTGCCGC
+ACGGTTTTAAAACTGTATTTTTCTCAATAGAGCGAGAATTAACAAGAAAA
+AATAATTTTAAAACCGTGCGGCAGTTGCAGAAATGGGCGTATTGCAAGCC
+ACGGTTCTGTGGGCGGGGCCAAACTCCCGAGTTGGTAATCCCCCCAATTG
+GACATCCCCCGAGTTCTTCGGGTCTCCTTTTTTTTAATTTTGAATTGAAA
+AATTGTCCGAAAAGTGCAAACGTAGAACATCAAAACCAGTGGAGGGGCGA
+AATTTGATAGATCGCATGTTGCAAGAATGAGCATTCTACGAGTTTCGCGC
+CATTTCTGCGTAGCGCGCACAATATTGTGCAATAAATCTCGGTATTTGCG
+TACATGCATCATATCTTACGCGCAAATCATATTGGAAATTTCCCCGAAAC
+ACGGGGAGGCAAAGCTAACGTGGCTGAAGAAATTTCTACAGTAGTCCCAT
+TTGGCTGACTGAATATTCAACGCGAATAAGTTTTGTACACTATTGCGTAC
+TTTGCGTACGCGCATTTTATTTGACGACAATTCGTCAATATCAGCTCTGG
+CTAAAAGCGCTTTTCTCATTATTTAAGCGAATAAAAGTCGAAAAAAAATG
+TTTTGTGATAGAGAATAGTAATTTAAAAAATAAAAAAGTGCATATTTTAT
+GTTTCTCATTATGTTTCCACTGATTTTCTGAGAAAAACCGAAAATTTCCT
+CTTTTTTCGATGAATTTCAGCTGAATAGTTTGTTTTTATCTAGTTTTTCT
+TCCGATTGACTGAATAACACATTTAATAACATCAATATAACGTTTAAAAC
+ATTCATTGTCTCGAAAACCAATATAAAACTCGTCAGAGAGGGATACTTAG
+TAGATATGCTGAACAAGGAAAAGAGAGAGAAGAACATTAACCGAATGGGG
+AGGGGGGAATAAGAAATCTGAACAGGAACGAAATATAAAGAACATTATTA
+GAAAGAACAAGCATGGCTTGATCTTCTTGGCAGTCGTCTCCTTATCCTAT
+CACTTCTTCTCGGCGTCCTTCTGATCATGCTACCGAGCAACGTGGCACGA
+TCGAAGAGTTTCACAACGGTTTGATACTTTCGCTCCACGAGGGGGCTCCC
+AATTCAGCGAGGGTCCTCTCACGAAGTTTAATTTTTTAAAATTAAAAAAT
+AAGTAACACCTCAAGAATTCCATCGAAGTTGTGCTCCTTTGCAATAAGAC
+GAAATTTTTTTTTACGGAATTGAACAGGATCATTGAGGTACGGCATGAAA
+ACGGCTTCCTCGTTGAACGATGTTGAAGCTCCTTCACCATTGCACCTGAA
+AATCAACTTCTAAATTTTCCAATTTAAAGAAAATCCACATACTTATCCTC
+GGAAACGAATCCAATATTCTGGTTGCTGAGTGGAATTGCTTCAAAGATTT
+TGATCAGATTTTTTTTTGAAATTTTCGATCACACATCTTGTATCCACCAA
+ATCGCCGAGTGCTTCATGAACTTCAGACTCGTGCTTTCCAACCTCTTCCA
+TGAGCTTCACTTCTTCTGCTTGGAACTTTTGATTGCCTTCGGACCGATCT
+GACTTGTAGTTTCTTCTTAAATAGTGGCTGATTGAGCAGTCGACCTTGCA
+GTCCTACCTTCTTTGGCTTCTTCTGCGGCACTTGAGCCCTTGTAAGAGCA
+CTTATTGCTGCTTAACCTTCCTTATTAATACTTCGAACAGCTTCTTCTTG
+TTCGCATCTATTTCGAATTTTGTCTTGAAATCTTCCAATGCAGCGACAAC
+GTAATATCTGGAAATTATAAAAACATTAAGAGAAAATATTTTGAAAAAAA
+ATCGAAAATTGCACTGAATTCCTAAATTTTTTATTAAAATCGAAAAAAAA
+AAATGAAATACGTGAGATTGAGTTTCGAGACTTTTTTATTCAGAATCAGC
+ATATATTTCTCCATATTTGAGTAGGTTTTCAGAAATATTGTACCATAATT
+TTTGGAAAAATGTAATTTTTAATTCGAAATTGCACTGAATTTCTCGAATT
+TTTCACTAAAATCGAGAAAATAAATATGAAATACGCGAGATTGAGGTTCA
+AGACTTTTTAATTCGGAATCAGCATATATTTTTCCATATTTGAGTAGATT
+TTCAGAAATATTGTACCATAATTTTTCGAGATATTTTGAATAATAACTTA
+CTTTTCGACGTTTTTTGCCTTTGTCCGGTTTAATCCATCGAATTTCGAAG
+CGGTTTGCGTAGATTAGCTGAAAACATTATGCTTATTCCACGTAGTAACA
+AGAAAAAACAAGAAAAAATAAGAAAAAACGAAGAAAAATAAGCATATAAG
+TCAAATTAAAAATGTTTATTCGATCAAAATTCTTAACCATAGGAGGCGGT
+GGCTAGCCGGCGCACTCTCGCGGCCACGTTAGCTTTGCCTCCCCGTGGAA
+AGGAGCCATGATATTACGGAAACACTATTTGAATTCTGAGAACGCGAAAT
+ATCTCGTAGCGAAAACTACAGTAACCCTTTAAATGACTACTGTAGCGCTG
+GTGTCGATTTACGGGTTCGATTTTTAAAATTATTTTTTTTGTTTTTTGTG
+TGCGTCATCGATTACTAAATTATAAATTATTTCCGTAAATCGACATACAA
+TCGCTACAGTATTCATTTAAAGAATTACTGTAGTTTTCGCTACGAGATAT
+TTTGCGCGTCACTCCTTCAGGCACCACATCTTACACTCAAAATCGAGGTG
+AATTTCTGTGTATTTGACAGCAAAAATGTCGTGAAAAACAATTAAATAAG
+GCAATTTGAAGAGGAAAAAACTGGGGCAGATGTGAGATAAGAAGAAGAAG
+AAGCGGGGCTTCGACAACCGTAAACTAATCAGAGATGGAAAGTGAGAAAT
+TTGAAATTTAAGACAAAAAAGTTAACAACGGGGGATTTTTTTTAGAGAGA
+AAGAGCGAGTAATCGGGCAGCAGCAGAGAAAAAAAAAGATAATAAACAAT
+TGAAAAAATATAAATATCGGGGAAATTATTGCTGAATAGACTGCAAATAG
+GTGACAATCTCGGGCGGTACAGAACGAAGTGTCTCTGGACAATTTCCGGG
+TCCACGGACAAGAACGGCCTGCGCAAAGTAGGCCTTGTGGTTGGCGATGT
+TGGCGGCGACGGGCGGTTGCTTGGGAGCGTAACTCAGACGACAGAATGGG
+TTCACAAATTCTCCCTCGGCGTTGTACATTGAAGCTTGCTCTTCTTCTGG
+TGATAGGACGGCTCGATCGGAGGCTGAAGCAGCTTCCAGCAGCATTGCCA
+CCTCGTATGACAGAATTCCGTATTGACCACTGCAAAAAAAATTTATATGA
+GAAATTGAATTTAAAATGATTTTATTTGTAATTTTGTTTTTGTTAATTGT
+CGTTAATTGTTTTTTTTTTGAGAAAAAACCGAAAAAAAAATTAAAATCTT
+CATTTTTGATTTAATTTTTTTGTTGAAAAATCGGCAGTTTTCGATTTTGT
+TTTTTTGAAAAAATAGGGAAAAGTCGGTAATTGTCGATTTTTCAAAAAAC
+TGAAAATTCCAGATTTTGTCAGGAAAAAAAACGAAGAAATCGACAAAATT
+TCAATTTTATTTTTTTAAATTTGTGTTTTTCAAATTTTTTTTTGATATGT
+GATTTTTAACTTTTCTCTGGAAAAAAACCGAAAATTTGCAATTTTTCAAT
+TTTTTCCAAAAAAATCTTTAAAAAATAGAAAATTTTCGTTTTTTTTTCTG
+AAATATTTAAAAATTGTAACTTTCTATTTTTTTTAAACCCGTATTAAAGT
+TTAAAAAAAAAATCGGAGAAAAAAAAACTGAATCGAAAATATGTGATTTT
+CAATTTCCTTTGAAAAAAATATAAAAAATCGAAAATTTTCGTTTTTCGAT
+ATTTTTTCTGGAAAAAAGCCTAAATTTTCATTACTAACACAAGCTGCTGC
+GTGACATCGGCTAGCAAATTGCCCATTCCAATGGCAATAATCCGTTTCTC
+AGGCCCCGTTGTCGTTTGTTTCAGACCTGGCAAATCAATGCATACGACCT
+TCTCGATGAGCATTCCGAACATGCCAGTCTGAATATTCTCACACGATTGA
+ACAAGATCCTGTGCACTCCGGGCGATCGTAAATCGACACAAGAACACGAT
+GAATAGCTTCATAAACTTGGGTGTCTTCGACGATTGAACTCTTCGAAACA
+TTGTATTGAGCACAAATGTCATCGCGGAACCCTCGAAGTGCTCAATCGAC
+GGAAGAATCGTCGCCGCCAACTGGAAACCGTATTGATCCAAGGTTTTCGA
+GCCCAAAAGCCGCGCCAAATGGCTCAAGATCAACCCAGAATTCTCCGAGA
+CGACTCGCTGAGCATTCACGGAAAGGATCACTTCGAGAACCGAAAGTGCC
+GCTGGAACATTCGCTGATCTCGCCCAAAGACGTTCGGATAGCAGAAACGG
+AAGGAACGGTGAGAATTGATCGATCGATGAGTTTCTAGCGATACATGAGG
+AGACGAGAACTCCCGTGATTTGGAGAGCATATGGGATGAGATCTTCCAAA
+TCCTCGCGGAAGATCACTTCGATCAGTGGAAGGAGTTGAGCATCCAGTGA
+GGCGCCGATTGTTCGGGTCTGGAACAGGAAATTCGTTAAAAAATATAAAA
+TGTTCTTAAAATTGCTATCACTTTTTTTTTGAATAAGAAAAAAAATCACA
+AAAAGGAAAACACGAAAAAGCAGACAAATGTTTCGATTTTGCAATTTTTA
+ATTTTTTTTTTTCAGAAAAAAATTATCGATTTCTTCTTTAAAAAAAGAAG
+ATTCTTTTCGATTTTTTCGGAAAAAAACATCGAAAAATTGAAAAACAAAA
+AGTTTTGATTTTTTTTTCAGTGAAAATCGTTCAATTTTTCGGGGTTTGTT
+TCGACAAAAATAATTAAAAACTAAAATTTTTCAGTTTTTAGGTTTCTTAT
+CAGAAAAATTGAATTTTTTCGATTTTCCGAAAAATTAAAAAAAGGTATAT
+TTTTTGAAAACACGAAAACGGAAAAGTGTTGGTTTTTTGTAAATTTTTGC
+GTTTTCCAGCAAAATTGCCAATTTTTCCGAAAATTTTCAGATCGAAAGTT
+AAATTATCGATGTCTATTCCAATTTCCGAGTTTCAGCGAATTTTTTTTTG
+CAGAAAAATTTCAGAAAATTTGACAAGTTATGTTCCAATTTATGAAAAAA
+AATTTGAGACCAAAGTGCGGCACGGAAAAATGGGCGGAGTTTAGAGTGGT
+ATTTTTCTCTCAAACTACTCCTTACCTTGGTGATCAACACACAAATCGTC
+TCAAACAAAAAGTGCGTGTGCACCGAATCCGCCGGATTTTTCGTCGCCGA
+CTCGACCAACTGTGCGAGCTTGACCGCAATCGCGTCCGCATGCCGAATCG
+TGTCGTCATCGAGAATCACAATGATCCTCAAAATCGCCTTGATCAGATAC
+GGCGAGTTTTGCGCTTTGGCATCCTTGTCGAACGCGGTGACAAGGTTCTG
+AAGGATCGAGGAGACTGGAAGATTTTGAGCCGAGAAGATTTTGTTGGAAT
+CAGCGAGAAGGATCTTTTCAATAGCGTAAGCTGCGTACTTGTGCAGAATC
+GGAGTATTCGAGCTGAGAAGAGCGTCCGCCGACTTGATCGCAGTCATAAG
+GTGCTCTGGAGCCAGCTGTTTCCTGAAAGTGACCGCAAACTTCAGTGCAT
+CAGCTTTAAGGATCGGAGTTTGATTGACATCGGCGTTGAGATGTGTGGCC
+ACTTGTGTGATGAAGAAGTCGTTGATGTCCACCAGCGGGTTCGTCGCCGT
+TACTCCACTCTTAGCAGTCTCCGTCTTCACCGCGATCGCCGTGATCAGCG
+AGTAGACAATGTCGATCTTGATCCAATCACCACTTCCCAGCAGGTTCTGC
+ACGATCTCCCCCAGACATGGAAGCATTTGCGCCTCGAATCTTCGGCAGAG
+ACCTCGCGCAAGATCGATGGCTCCACGGCGTCGAGTTCCTACATCGGTAC
+CCTCGATGTCTCGCTTCATATAATCCAGTGGCTCATCCTCGAACAGTTCC
+ATATCCTGTTGACGAAGCAGAAGGTTCTGAACGCACACGTTCTCGGCGAG
+AGTCTTCAGAACGCCTTCACCAGTGAAGTGTCCCTCGTAGTACTGTCGCT
+GGCTGACCATCGACAGAAATTCCAGCGCGGCGCACACCATCGTATCGTAT
+CGAGTGTCGGGGCCGGTAGACTTGAGCAGATTCCAGACGGCAAGGATGAT
+GTCGGGCACGAACTCGGAGATCTCCTCCTCGTAGCGTTGCGAGTAGAGCG
+TGAAGATCTCACAGATCTCGTGCTTAAGCTCGTCCAGAGTTGTAGGTTCT
+CCCGAGTTGGAGGTCTGCGTCGGCGCGTCGATTTGCACGAGATGCAAGAA
+GTGTGGCATCCAGTCCTTGAGATGATCCTCGAAGTATTCCGGAATCTCCT
+GTGAGCACAGAGAATGGTAGACTTTTGCAATGAGAAGTAAGACTCGGAGC
+CATTGGGCGATCTCGTCGGCTCCGAGTTGATCCTTCCGCTGTCCCACCTC
+CATCATGTTCCGTAGCAACAGAGTTAGAGGCTCTTGGGTCTGAAAAATCG
+GTTCTTTTTATTTGTAACTGAAAAATCTGGGGAGAAAACAGTTTTTCGGT
+CCAAATTCGAGACTGACATTCAGATTTCTTCAATTTTTTGGCTCAAAAAT
+TTTGAAAATTTGTCCATTTTTATAGGAAAATTATCAATTTTCGCCAAAAA
+TTCCTCATTTTTGCTTTAGTTAAAATTTTTGACTAAAAAATCATAAAATG
+TTGAATTTTTCACGATTTTTCGGAAAACAAGGCCAGCTTTAGCTAGCTTA
+AATGTCTAATTTTGGTCATTTTTTAGGGTCAAAGCGGACAAAAATTCAAC
+TTCCGACGGCTGCGACGTAAAAAAGTGGCCAAAATTGGGGATTTTAGCTG
+AAATTAGCCAAATTTTGAGCCAAAACGCAACTCACGCTCAGTAGACACTT
+CTTCAGCTCTTTCCAAAGCTCTGCTGACTTGGATTCGAATCGGAATTTGC
+GGAAAATCTGCTCCATCGACGCCAGCGAGGCCACCAGGTGATTGAGATCC
+GCTCCGTTCAGGAATTTCGACAAATATGGAACCAAATCTGGCCATTTTTC
+GGGAAAATCTCTCTGAGCGATGAGATACAGAGCATTGGACAGGATTTCCT
+GAACATTTGATTTTGTATTGAACATCGCTTCGAGAAGCATGCTTCTGAAC
+TGCTCCTCGTCTTCCTGGCCCATTTCTACCTCTGGTGCCGGGCCCTGAAA
+CAATTTAAATATAAAATTCACGCATTTATTCAAATTTTCCAACCCAATTT
+CTCTTCACAAAATTTTTCAAAGCGACAGCCGCGGCGATTCGGATCTGCGG
+AGCAATTTGTTGCTGTTCGTTGACCACCAGTTGAAGAATTTGAATGATAT
+AGCCTGGATTTGATTGCAGCGAGCGGAGCGCTTCTTCTCCACGCTTGCGA
+ATCGCAGCATCCGGCTCCAGAGTCTGCTGGAGAGCTGCTCCGATTTGCTC
+CATCTGAAAATAGGGAAAAATAGCTGTTTTGGGGGTGAAATAGGGAAGAA
+TTAGGTGAAAGGACAAAGATAGTTTAGCTTAAAACTTGAAATCTAAAATT
+TCCGGTCAAAATATTAAAGTTTTACGCAATTTTTCGCAGGCCCGCGGGGA
+ATAAACTCGCAAAAATTCGCAAAAATAAAAAAAAAATTTCAAAAGTGTGA
+AGTGTTTGCGTACAGCGCACCCGACCCGACGCGCAAATTTTTTTCATTAT
+GTTCTCTGTTTTCACTGATTTTTACTGATTTTTCCTAGTTTTCCCTTGAT
+TTTCTTCAAATTTTCCACTTTTTCAGCAAAACGTGCATAAAAAAATAAAT
+TAAAACATTTCAATTTTCAAAACTTTGCAAAATAAAGGCGTCGTTGCGTA
+CAATGCGCACGACTTGACGCGCAAACTTCCCAATTTTTATTCTTAAATTT
+TCCTGGATACCCCTGGTTTTTTCTCTGTTTCCCCCCTAATTTTTCGCATT
+TTCAGCAAACATGGGTGTTGATAAAAAGCAAAAGCAACGAAAAACCAATC
+CATTCGAGCTAAAATTCAACAAATCCAAGCATGACGTGAGTTTTTCAGAG
+TTTTGAAGAAAAAATCGATTTTCTCGCAGATTCTCGGCCGGAAAAAGGGC
+GCACAAGTTGGAGCACCGACTGCGTCACGAAAACGAGCTCACGAGCAACG
+TGAACAGACGCTAGGCGTAGAATATGACCGGAAAAATAAGATTAGCAAAA
+TTGTCGACAAACGGCTCGGCGAAAAGGACGGAAAAAGCGAGGAGGAGAAG
+GGCGCGATGAGATTCACAGAGGAAAGAGTCAAAAATTATAAAAGAGCATC
+GAAATTCAACTTGACAGATGATGGAGATGAGGAGGAAGAAGGTTTATTCC
+GAAATAAATTGAGAAAAATTTTAATAAAGTAAATTTCAGTACTTACTCAC
+AAGGGAAAAGCGCTCTCGGACATTGAAAAATACGACAAATCGATGATTTC
+CGACTCGGATGACGATGAAGAGCCGGGAAATTTGGGCTCAAATATGGTAA
+AAGTGGCTCATTTCGGTGGTGGAGAGAAGACCGCCGAGGAGCACGTCCGC
+GAAAAAATCAGCCGAGAGGATATGATTTCGAATTTGATTGCGAAAACGAA
+GCTGGCGCGTCACGAGAAGCAACAGCAGAAGGATGAGCTCGAGCTGATGA
+CAGAGTCGTTGGATTCCAAGTATCAGGCTTTGATGGGCAAAATGAAGGCT
+TCATTTAGGCCGACCGGGCGCCAGCCGCTGGAAAAAGATGATTACGACAA
+ATTGGTACGGGAAACATCCCGGTTTTCTCCAAATTTTTAAGATAAAAGAT
+AATTATAAATTTAGAGTGAAAATCGATTTTTTTCACAATTTTTTAGTGGA
+AAACCTAAAACCCAAAAAACTTGATCTGAAAATGCTAATTTTTAACCATT
+TTTGCTATGGAAATTGGAAATTTTCATTAATTTTGCTGTAAAAGTTGAAG
+AAATCCAAGTTTTAGCTTTGTAATCAGAGAAAACACTGTAAAATTATTTC
+GGAATTTGTGCAATTTGAAGTGAAAAATAAAACATTTAACTTCTTATCGC
+GAAAGAAATTGAGCTGAACTGAGAATTTTTTTGACGAAAAATCATTAAAA
+AGTCAATTTTTTTGACAAAAATTCGAGAAAAGTCGGTTTTTCTTTTGACA
+AAAATGACGAAAAAGGCAATTTTTAATTTAAAAAAATAAATTTTTCGCCG
+AAAAATAACTTTAAAAAAGTCGTTTTTTTACAAAATAAAACAATTTAAAA
+TAACTATTTTTCGACAAAAAAATTAAGAAAAAGCCAATTTTTTTGTTTAA
+AAAATGATAGAAAAAGGCTTTTTTTTTGTTTCTTCGCCTAAAAAATCAAG
+AAAAATAGGTTTTATTCCATTTTTTATCCAAAAATTATTATTTTTCCAGA
+CAATCACCTTGAAAACCGAAGCCGACGCTCGTGCCACCCCAGCAGATCGT
+AAGCTATCCGAAGAAGAAGAAGCTCTGAAAGAAAAAGAACGTCTGGAAAC
+TCTCGAGGCCGCCCGTATCTCGAAAAATAATGCATTTTTCAACGCAAAAT
+CTCATTTATCAGCCGATGCCGACGTTGATATCGATGCTGGATCGAAGGCC
+GACGCCAGAAAAGTTCAGGCGAAAAATTCGAGATTTGAGGTCAAATTTGA
+CGATGAAGGTGGCCTGATCGATGAGGATACGGTGGAAAAATCCAGGATTT
+TAAAGAAAAATCTGGATGGTTCTGATGAATCTGACGATGACGAGGATCTA
+GAAGATGAGGAAGAGGATCTGGATGATCTACTGGAAGATGAGGATGAGCT
+GGAAGAAGATTCCGATGATGAGGAAGCTCAGGAAGCCCAAAAAGTCGTCA
+AAAAAGCGAAAAAATCTGCTCCAGAACCCGCTGAAACTCTGCCATTCGTA
+TTCGAAATGCCGAAAAACTATAAAAAATTCTGTGCTCTTCTGGAAAAACA
+CTCGGAATCGATGGATTTAGTGCTGGAACGACTCGTGAAATGTCATCATC
+CGAGCCTTAAAGAAGGAAATAAGAAGCGTCTGAATAAGCTTTTCCTCTTG
+TGTTTAAGATGGTTTGATGATATGTCGAAGGAGGAATTGACAGCGGAAAG
+TGTGAAGGAAATGAATTTAGCGCAGGAAACTATGCATGCGTTGATGAAGG
+TAGCGATTGGATGGAAAAGCTGAAAAATTACCGCACTTTTTAATCTGAAA
+ATTGAAAAAATTCGAGAATTTTTGACCTAAAATTTTGAAAAATTCCCGAT
+TTTTATACCCCAAAAATTGCAAAAAAGTCCCGATTTTTTACCAAAAAATG
+TTTTAAAATCCCCGAATTTTTTACCTAAAAATTGCAAAAAAGTTTCGATA
+TTTAGACCCAAAAATTGCAAAAAAGTCCCGATATTTTTACCAAAAAATGT
+TTTATAATCCCCGAATTTTTGACCTAAAAATTGCAAAAAAGTCTCGATTT
+TTAGACCCAAAAATTGCAAAAAAGTCCCGAATTTTTTACCAAAAAATGTT
+TTAAAATCCCCGAATTTTTGACCTAAAAATTGCAAAAAAGCCGGTTTTTT
+TACAAAAAAATGTTTTAAAATCCCCGAATTTTTGACCGAAAAATTGCAAA
+AAAGTCTCGATTTTTAGACCCAAAAATTGCAAAAAAGTCCCGAATTTTTT
+ACCAAAAAATGTTTTAAAATCCCCGAATTTTTTGACCTAAAAATTGCAAT
+AAATTCCAAAAACTTTGGCCAAAAAATTAAAAAAAATACCCGAATGTTTG
+ACCCAAAAATTGCAAAAAAGCCCCGATTTTTTGAGAAAAATCATGTGAAA
+TTAAAACCTTTTTTTTTTGAAAATCAGTCTCGAAAAAAAAAAGAAAAACC
+AGGAAAATCATGAAAATTTAAGAAAAAAATCATTAAAAATAGGAAACGAT
+CATGGAAATATTTTTAAAGAAACATTATATAAAAAATCATTAAAATTTCA
+GAAAAAAAATATGGAAAATCCTGAAAATAAAGAAAATAATATTAAAAATT
+CAGATTAAAAAACGCAAAAAATTCAACAATTGAAAAAAATTTCAAATTGT
+TTTTTGCAGTTCGACATTCAATACGGAGTCCGATGTGTGCGTGCTCTAAT
+CCGTCAACACTGGAAAGGCCGCCAGGATAAACAGAAGAGTAGCCCAGTGT
+CATTTGGATTAATCTCTGCAATTCGTCTTGTTTCCGGCCTCTTCCCAGTT
+GCCGATTCCTGGCATCCTGTAGTGGTTCCGGCTCTTTTTTTGGCAACTGA
+AGCACTTTGCTCGGCGAAATGTGCCAATTTGAATGCGTTGGCTAAACAAA
+TTCAATTGGCTAATGCTATTGTTGAATATGTGTCTGAATCCAAGAGGTAA
+TACTTGGAAACGAACATTTAAATAGGCAAATTTTGAAAAAAATACTGAAA
+GCTTTGATATAAAATAGGAAAAGTAACGAAAAAAAAAGCCAAAACCACCA
+AAAATATTATTTTCAAAAGCTAACTCAAAAAATTTAAAATTCAGAATTGT
+CGCTTAAAAAAATCTATTTTTTTCGATATCGAAAAAAGATTACTATAAAA
+ATTCAAAAAAGCAATTTTTTAAAATATAACTTGATTTTTTTTTCTGAAGT
+TCATTTTTTAACAAATAATTGCATTAATTTTCCATTTTAATGTTAAAAAA
+AAGCGAATTTTTCAAAAATTGATATAAATTTTGTTTTGGCAATTTTTAGA
+TCAGAAAACATTGAAAAAATACAAAAATCCCGTTTTTTTTTAAATTAATT
+TTTTAGAAAAAATTGCAATTTTTCAAAAATCTTCCGGTCATTTCTCTATT
+TTTAAAAAATCTCTCGTCTCTTTTAAAAAAATTTAAAAAACCGAATTATC
+GAAGCGTATCAAAATTTTGAAATTAAAAAAAAAACCGAACTCCATTTTTA
+CGAAAAATCCGAAAGTTGAAAATTGTTTTCAATAAAATAAATTTCAGATA
+CGTCCCCGAGCTGGTCGCATTTGCTCGAAGTGCTCTTCTGCTTGCAGTTA
+CAGAGAAAAGTGAGAAATTCGCGACAAATGGATTCCCGATTTCCAAGCCA
+CACACGGAAATGTTATGCTTTGAGGAGAAGGTAAATTTATAAAATTTGTT
+TTTTTGAGCAAAAAATTGGTTTTTTTTTTTGGTTTTCTCTTTAAAAAAAT
+TTGCTTAAAAACGCTCAATATTTAAAAAAAAAACTGGCAAAATCGAATTT
+TATAATATAAATTAAAAATTTTGTTCAAATAAAAATGATTTTTTTTTGAA
+AATTTAGTTTTGAAAAATTTAAAATTAAATTTTAAATTTTCACAAAATTG
+CCAATGATAAAATGTTCACTTTTTCTTGTATAAAACTGCTTGAAATTTTT
+TAAAAGCAATTTTCCGAAAAATAATTTTTTAATAGATTTCTGAAAAACCG
+AAAAACCACCGATTGAAAAACGAAAATCAAGTTTTTTTCCGAATTTTCTA
+TTTTTAACAAATTAAATATCAATTTTGCACATACAAAACGGTTAAAAAAA
+AACAAAAAAAATTGCCGAGAGCCAAAAAAATTTAAGTTTCAGCGATTTTG
+AAATTTTTTTTTTAGGAAACACGGTCTCCTCGGGTGGAAACGAAGGGGGA
+GGGAGATTGCTTGCGCGTTTCACCGATGCGCCTTTCGCGTGCTGGCGCAC
+TTCTGAATATTGAATTATTTTTGCGGAAAAAATTCATTTCTTCTATGAAA
+TTTTCTTGAGAAAGCAAAGGAAAGATGATGAAATGAATTTTTAAAATAGT
+TTTCTCAGTTAAAAAGAGAATACCTTGCTGCAAAAGGTTAAATTTATTGA
+AAAATTGAGAAAATAAGAAGTTTATCTTTGTTTTCACTACATAAAGTGGG
+GAAATCTCAAAAAAATTTGAAGACAATTAAGAAATATAATTAAATATATA
+GCCTGAAAGTCAAATAAGAAATGAAGGTTTGGTCACAAACAATTTTATTT
+TTGAATTGAAGTTTTGAGAAATGATCATGTGCCAGAATCACTAAATCTGA
+GACATTCAGCCCAATTTCTTTAATTTTCTGTGATTTTATCATGGAAGTGT
+GGCTTTTTCTGTGATCTTGCCAGTTTTAACAAGTTGAAATTGGAAAATCG
+TGAAGTGGGAAACTAGCAGTGAAGCTTCCAAAAATTTCAAGCCTTACTGA
+AAGGAAAGTATTGGAAACTAAAAACGAAAGCTTAAGAAGATACCGTTTTT
+ATATATTTGAGTTTTGAAAAGCCTTAATAGGTTTTAAATACAGTTTTCTC
+AAGAATTCAAACTTGTAACGATTAAGTTGAGGCACAGAATAAGATGGTAA
+TACTAAGTTATGTTGAAAAAAGCCAAGAAAGACTGAAAACATTGCTTTCA
+ATCTGATTTTTTGTAAGTAATGTAATGTTGAAACATTATTCTTCATAGTT
+CAGCACTTTGTATGGCTTATTTGAGCCCAAACGTACAGTAGTATGTGGCA
+AGAAATAAAATATTGTGCCAACAAAATTGGAGCCGAAAAACCCATGATAA
+AATGTTTAATACGTGTATTGCTCTAATAAAATACCAAATATTAATTAGAT
+TCACTGTCTCGACTCTTTTTAATTCAGATTAATAACTTTTAGCTCCTCTT
+TTTAACGAAAAATTATAACTGGATTTCACAAAAAGAGTTCGATCTGAGTT
+CTTTCAACAGGTACATAGACGAATTATATCTTAAAATGACGAGAAAAGTT
+TGCTCTATAAACGTTATCATTGCAGGTTATGAGAAAAACAAATAAAAATT
+TAATTTTAAAAAATCCGAAAATTCAGTTGTTATTTTCAAACAGTTCGTTA
+TGCATTTCCACCGAACGGTTTCCGATAATTTTTGTTTCTCCACTTTCGGT
+TCAGTCTACTTTATAATTGTTATCATTTTGAAATAGAAAAATCGACGAAA
+AACTAATAAAAATCGAGGGAAATCACTCTTCAACGGTGAAATCTCGGTGG
+ACGCAATGAAGCTGCAGCATTTCAAAAAAATTTTAGAAGCAATTTTGGTC
+ATTTCAGCTTCAAAAAGCTTTAAAACTTAAAAAAATTAAAATTCATTTCA
+AAAAATTTGAAATTAGTCATTTAAAATATAAAAATTAGAAAAATTCTAAT
+TTTCAGCGAATTTTCAAATTTATTTTTATTTCAGAAAAATTCAAATTTTG
+GCTTTCAAAAAAGCTTACAAAATATTAATTTTTAAAAAATCTAACTTTCC
+CAATTTTTCAGTACACTGGCCCCGCACTCCAGCCAATCTCCCTGACCACA
+ATCTTCAACAATTCCCCATCCGATCCATCTCTAAAGCTTCACGTTCTTCG
+TGCTCTGCTCTCCCTCATCCAACATCTCCGTGTAATCTACTCCAACCAAA
+ATGAGACCTATTCTATCGTTTTCAAGCCATTCCTCCGGATTTTGGAATCA
+ATTCAAGCCAAAAATCTTCCAGCCGAGGTCCAGGAAGAGCTGGAGACTCT
+GTGCGCCTCAATGAAGGCTGAAATTGGAGCCAAGTGCCGTCTGGTGCACC
+TGTCGCTGGTGAAAACCGAAAAGAGCATGCTGAAAATGCTGGAACCCCGT
+TTCGAGTGGGATTTCGATCCGGAACGCCCACATCACGGACCCAAAGACGA
+GAAGAAGAAGCTGACGAAGAATCTGAGGAACGAAAGACGCGGAGCCATCA
+AGGAGCTCAGAAAGGATACGGCATTCTTGGCCAGGAAGCAATTGTCGAGT
+GTCAAGACGAAGGATCGTGCGAGAATTGCGGCCACGAAACGTGTCATGGG
+CGGTCTTATGCAGCAGCAGGGTGAATGGAATAAGGAGAAGCGTACGGCGG
+ATGTTGAGAAGAAGAAGGACAAGAAATAATTTAAATTTTCCTATTTTTTG
+TTTGTTGAAAATGACTTTATTTGGCAAAAAAAACCCCTAAATTTCAGTTT
+TTCTCGATTTGTTGAAAAATAGTCAAAAAACTGATTTCTATGTTATTTTT
+GGTCAAAATTTGCCTTTTTCAAACATTTTTTTTGCCATTTTTCCTCCATT
+TTTTGTTATTTTTTTTTTTCGTTTTGTTATGAGATATGTTTCTGTTTTGT
+TGACATTTTTTATTATTGAAAATTAAACGAGTTTTCTGAATTTTTTTGTT
+CAATTTTTTTGAAATTTTCCGTTTCACATACGTTTGTCAATATCTCGATT
+AATTTTTGAAGTTTTCCAATTGACTCGCGCATTTTCTAAAAAGTTTTTAA
+ACTTTACATTGAAAATACCCCTCTAACTCGAATATCTGATTTTATTGGAA
+TTTTGAGTTTTTTTAGGTTAAAAAATTCTTGTGCTAAAATCATCCATTAT
+AGTTCGTAAGTCAGCAAATTTTGGCTCAAACTTAGAGCGATTTCCAATTT
+ATGGAGTTTTTTGTTCAGAATTCTCGAAATTTTCTCATTTCTGGAAATTT
+TGAGTCTACGAGTCACACAGTTGTTCCGTAATTAGCTTCACTTACATCTC
+CTCAACTCTGCAAACTCTCAAACTTTCGGGAAAGGGTCTCGCCACGAAAT
+CACGGGTGGGCGGCAATTGCAGTTCGGCAAATTGCCGGTTTGCCGGAAAT
+TTTCAATCCCGGCAAAATTCCGTTTGCCGGAAGTTTTTAAACGGGATCTT
+TTATAAGACGGAAACACTTAAAACTGCCATTTTTAATTTTTTGCCCGTTT
+TCTCTAAATATTTTCATAGAATTTACTGACTTTTTAGGATAGATGTTTTC
+ATGGGATGTGCACATGTTGTTCCGGCAAATCGGTAATTGCCGAAAATTTG
+AAAAACGACAATTTGCCAAAAAAATCGTTTGCCGTTCACCCCTGTATTGT
+ACCATTTTTGGCGAAAATGCGCGTAAATTAATATGCTTGCGTGTGTAATA
+TTTCGTTCATATATTCTAAATATACGCACCTTTTGAAATATTCATAATAT
+ATGCATTTACGTACGTTCGAGAATATTTTGGGAATACACATTTATCATCA
+TTCCCACCCGTTGCCATAGTATCCTCATCCCCGCCCCGCCCCGCCCCTTT
+CTCTCATTTCCTCTTCCAAATCCTTAATGGCTCATCCGGTCATTGGAGAG
+ATATGGCAGATGTGGCGGTTTTGACGAATGTTCTGGAGAACTCGAATTTT
+ATATAACTATTAGACAATTTCGATATTAAAAACATTTATATGTAAAATTT
+TCAATTTTTTGAATTTGCTCGCCGAATTTTGACTTTCTGACAATTGTGTG
+TCGATTTACGAGGGTTATGTATATTTACGATATGTTTTTAATCATTATCG
+AATGCTGATTTCCGTTTTTCTACGAGTTGTCTTCATTTTCGTTGGTTTTT
+TTTTGTTTTTTTTTTTTGAAAGTGTATTTTTTAAGGTCAAAAAACTAGAA
+AAATATTCAGTTTTCAGTCAGGAAAACCATTTATTTGGTTTTTTCAATAT
+TAAAAAAATTATTGGGAAAAATGAATGAAACTCGTCGAAAAACGAAAATC
+ATCATTCGATAAAGATTAAATATTTCGTAAATCGACACACATGTCTCCGC
+CGCGAAAAATCGAAATTTCATAGAGGCATAAAAATTCACAATATTTTAGT
+TTTTTTATTTTTTATTTTAATCCAAATCCCTATTCATGCTTAGATTTTTA
+GGTGTTTTTCTGTAAAAAATCAAAAAATTGTATATTACTCATAAATTTTT
+CCAATTTTCTCAAACCTTGGATCTCGCCACGACATTATTAAAAAATTCCC
+GTTTTCTGCAGAAATGACGACAACGGAAGAAGCTCCCAAATCGCCGCTTT
+TCGAGGCAATCGACAAAAATGACACTGAAGCAGCGCTGGCACTGCTGAAA
+ACGAAGGAACAAGCCGCTCAACGGGATCCCAGTGGAATGAGTGTGCTGGC
+AGCTGCCGCGTATAGGTATGCACCTTTAAAGCGGCGACGGTTACTGTATC
+CTCGCAGATTGTTTAAAGGTACATACCGTAATCCGTTGAATTTCAGAGGA
+AATCTTACGTTGGTCGAGAAAGCGATTGAGCTGAAATGTGATGTGAATGA
+TAAAACCGATGGAACTCTGTACACTCCACTCATGTTTGCCGCCTTATCAG
+GTAGGGCAAAAATTTTTTAAAAAAATTTTTTGCGTCAAATTTGATGCAAA
+TTCTGGTTTTTTACCGTTGAAAAGTAAAAAAAAATTCCGAAAAAATCGAT
+TTTTATGCTAACAACAAACTTTTAAGTGAAAAATCGTGGAAAATTAGACC
+CAAATCACGTATTTTTGATCTGAAATTCAATTTAGCGAAAAGTCATCGAA
+ATTTTATGGTTTTCGCGGTGAGACCCAATATTCGCAATTTTTTTTTGCAC
+CAAATACAACACATTTGACGCGCAAATTCAAATTTTTGAAACTTTTTTCC
+GTTTTTACAATATTTTTAGGCTGAACCCCAATATTTGAAAAAAAAAAAAC
+CAATACACTATATTTTACGCGCAAATGTTAAATTTTTATTTAAAATCCTC
+GTAAAGTTCTATTTTCTTTTTTTGATCGTTTTCAAGCTCAAAAATTCAAA
+TTTCAATTCGAAATATTACCGGAACACAAAATTCTGAAAATGCGTACTGG
+TCAACATATTTGACGCGCAAAATATCTCGTAGCGAAAACTACAGTAATTC
+ATTAAATGACTACGGTAACGCTTGTGTCGATTTACGGGCTCGTTATTAAA
+AATCATTAATTTCAAAAAAATCGAGCCCGTAAATCACCACAAGCGCTACC
+GTAGTCATTTAATGAATTACTGTAGTTTTCGCTACGAGATATTTTGCGCG
+TCAAATATGCTCAATACACATTCTCAGAATTTTGCGTTAACGTATTACTA
+CTTTCTTAGTTTTTCCAAAAAAAAAATTCGAATACACCATATTTGACGCG
+CAAACTTTTTTTTTCAAAGCAAAATTGTCAAACGTTTGCAGGAAAACAGG
+ACGTATGCCGCCTGCTAATGGACTCCGGAGCCCGTATGTATTTGGTGAAT
+GGAATCGGAAAAACCGCCTCTGAACTGGCGGCATTTGTGGGTCATCACGA
+GTGTGTGGCAATTATCAATAATCATATAACAATTGATGTGATCGAAGATC
+TTTTGCGGCCAAAAGTGAATGGAAAATATGAAGGAGCTGAGGAATATCCG
+GATGAGCTGGCTGTATTTATTCATTCATTGTGTGGATCACATGAGATTCA
+TCCTGTTAAGATTATTTTTCGATTCAGTAAATATCCCGATTCGTTGAAGT
+ATAAGAAAAAGGTACATAGCTGTGTAGTTTGGAAAAAAAACGAAAAATCT
+GAAAATTTGAGAAATTTCCTTAAGCTTTTTCAAGATGCGCATTTTTGTTC
+ATTCTTATTTTCAAAAAAATCCAAAAAGTTTTTTAAAAAATTTAATAAAG
+CATTCTTTTTAATTTCAAAACAAAAAAGTTATACCAAATAAAAACTTTTA
+GTAATCAAAATTTTTCACTTTTTCTCGGTTTTTCTCATCGTTTTTCAAAT
+TTGAGATCTCTTCCTGAATTTTGCCTAAAAATTGATTTTTTCAAAATATT
+TTCAGAAATGATTCTTTCTGTGAAAAAATGTTTGAAAATGCGAAAATATT
+CGAAACTAAAAAAACTTTTATTAAAATAAATTTTTGAAATTTTTCAGAAT
+TTAAAAATTGAATCGAATTAGGTATCAGTAGTTTTCAGATCGATTTTTTC
+GAATTTCTGAATTTGTTAAAAACTAGAAATTAAAAAAAAAACTTTTGATG
+TTAAATGTTTTTCGAGATTAAAATAAACCGAAAACCCAAAAAAAATGTAA
+AAATTGTGTTCTTTTTGTTATAATAAACCAGAATTTTCTCGAAATTTTCA
+GAAGGTTCTAGAATATTTCAGAATTTTCTCGAAATTTCCAAAAGGTTCTA
+GAACATTTCAGAATTTTCTCGAAATTTTCAGAAGGTTCTAGAACATTCCA
+GAATTTTCTCGAAATTTTCAGAAGGTTCTAGAATAGTTCAGAATTTTCTC
+GAAATTTCCAAAAGGTTCTAGAACATTACATAATTTTCTCGAAATTTCCA
+GAAGGTTCTAGAACATTCCAGAATTTTCTCGAAATTTTCAGAAGGTTCTA
+GAATATTTCAGAATTTTCTCGAAATTTCCAAAAGGTTCTAGAACATTTCA
+GAATTTTCTCGAAATTTTCAGAAGGTTCTAGAATATTTCAGAATTTTCTC
+GAAATTTCCAAAAGGTTCTAGAACATTACAGAATTTTCTCGAAATTTCCA
+AAAGGTTCTAGAACATTACAGAATTTTCTCGAAATTTTCAGAAGGTTCTA
+GAATATTTCAGAATTTTCTCGAAATTTCCAAAAGGTTCTAGAACAATCCA
+GAATAATGTTTTCAAAAAATTCAAATTTGAATTCCCGCCAAAATGTTTTC
+AAAAAATTAAAATTCGAATTTCCCGCCAAAATATGTACAGTACTCCTACA
+GTACCTCTACAGTACTACTACAGTACCCCGACCATATCCCACTACTAACC
+CCAAACCTATATCTCTTCAAAAGACTAAAACACAATTTTTCCTAAACTAC
+AGTAATCCTACCGTACTCCTACAGTACTACTACAGTACCCCCACCATATC
+CCACTACTAACCCCAAACCTATATCTCTTCAAAAGACTAAAACACAATTT
+TTCCTAAACTACAGTAATCCTACCGTACTCCTACAGTACTCCTACAGTAC
+TACTACAGTACCCCGACCATATCCCACTACTAAGCCCAAACTAATATCCC
+TCCATCAGCCGAAAACGCCTTGCCTTTGTAAACTATGACGTCACTACTTA
+ACAAACGGACACTATTTTTTTATATTTTTTTTTCAAAGCAAAAACCACCC
+ATTTTCCAGATCCTCTACGTCATCGATCGTGTCTTCGAGAAACAGCTTCG
+ATGTAAGGAAAGCAATGAAATAATGTCGCTCAAGCTTTGGCTAATTCTAT
+TTTCAATGCGTGAAACCTCGAAATTCGTGGAGTCGAACAAGGAAAAGTCG
+CCAGAAGAAGCGTCTCTACAGTACGCAAAACTGATTTCCACGTGGCAAGA
+GGGCGATGAAACTAGGCGAGCACTTGACGTGATGCTGAGAAATGCGGTTG
+CTTCGTTCCCGTATAAACATTCATTACTTCATGATACTCTACAAAAAGCA
+CTGCAAAAAAGTCAAATTGGTGAACGACCAAGTGCCTATGAATACATTGT
+TCAGGCACTTTTCGGACAACGAATCGCTGCGGTCTGCCAGTTTTGCTCGG
+TTTGCGGACATCCTGGAGCCAAGAAACGGTGCACACAGTGCAAAGTATGG
+AGTTTTTAGGGTTAAAAATAATTATTTAATAATTTAATAAAGCTCGAATT
+TGGGAAATAATCAATTCCAAATTTTAAAAATATGGAAAAAATTTTATTCC
+GTTACATTTTATGAATTTTCCCACAAACTCGGCATTTGGCTCTAGCTTCT
+TGCCCAAGTTTAGCCCAAAAAATATTAACTTGAAGCTGTCTAAACTTGGG
+CAAAAGTTAGACAAAACTTTGGCAAAACTTGGATTCAAGCTTTACCAAGG
+TCTAACCCAAGTTTCACCCAACTCTTGCCAAACTTTGGCCCAAACTTTTC
+TTATTTCGTTTCAAATTTGGGCCAAAGTTTGGCAAGAGTTGGGTGAAACT
+TGGGTTAGACTTTGGTAAAGCTTGAATCCAAGTTTTGCCAAAGTCTTGCC
+TAACTTTTGCCCAAGTTTAGACAGCTTCTGATCCAAGTTAACATTTTTTG
+GGCTAAACTTGGGCAAGAAGCAAGAGCCAAATGCCGAGAAACTCGAATAA
+AAATTGAAAGTTTTCAAAATTTCAGTTCGTTTTTAATTTACAAAATTTGG
+CAGCTCTAACAATTCTTTAAAGATTCTTTAAATTAAAAAAAAGAATTATT
+AAAACTTTTTAAAAAAATTCATTCTGTAGAAAATTCCCGTAAAATACTCT
+TTGAAAATCCGGGAAAAAACTTCAAAAAACAAAAATAAATTCTAGACATT
+CTGTAAATATCGAAAAAAGAACATTTTGTCTGTAAATGTATTAGTCAAAA
+TTAATTTCTGATACTTTTTCCAATTTTTCAAAATTTTAAGTGTCGAGGTT
+CAATTTTTTTGAATTTCCTGTTTTTCCTTTATTAAAAAAAGTTTTCTATA
+ATATGCTGTATTTGAAAATTAAAAACTATATCTGAAAATATCGAGGCACA
+ACGTTTTCAAGATCTGGTGAAATTCCGGATCTACGTTTTCCGGATCTACC
+ATTTCCGGATCTACGTTTTCCGGATCTGGCACCGTGCCAACGCACAAAAC
+GCTTTTTTGTTCACTCGACGCACGTTGTTTTTTGAAAATTTCTTCTAGAA
+GAAACGCTTAACAACACGCGACGCGTAACAACGGAGCATCGTTATCACGT
+TTTTCTCCGAGAAAAATAGCGTTTTAAGAGTTGGCACGGTGCCAGATCCG
+GAAATGGTAGATCCGGAAAACGGAGATCCGGAATTCCGCCAGATCTTGAA
+AATGTGGTGCCTCAAAATATCGATTAAAGAATTTTTTCTGAAAAATATCC
+AATTTTTCAACAACAGAATAGCTAAAAAGTGAAAAAAAACTCAATTCTCA
+TTATAAATTGCAAACAATTTCCAAATTTTGATAAAATGGAAAAGAGTTTA
+AAAATTTCAGGCAACACATTTTTTAACTCTAGTAAACGTTTTTTAAATTC
+CAACAATTTTTACAGCTCGCCTACTGTTCCCAAGAATGCCAAAAATTCGA
+CTGGCCAATTCACAAAAAAGTGTGCTCATTTCTGAAAACGCGACAAGAAG
+TGTCGCCCACCGACGAGACCGCCATGTCGCTGGACGATATTCAGGCTCAA
+ATCGCCAAAATCGACGTGTAGAAGTGCCGATATTTCGATCTCAATATACT
+TTTTTTCTGGAATTTATTTATTTTTAATGTATATTTCGGCTTCATCTCAT
+TGCACGAACTTTTAATTTCATTTTCATAAATTCATTTTTGAAGTCATTCC
+TTGAACAAAAATTCACTAAAACATGCATTAAGAAATATGGAATCCAAAAA
+TTAATCTAAAAACCTTTTCAAAAAACCACTTCGTCAAAAACTGATGATGG
+AAAACTCGTTGAAAAACGGAAAGAGTATCCAATAAAGATTAAAAATTTCG
+ACATTTCGTAAATCGACACAAATCTCGTAAATCGACAAAAATGAAAAAAT
+CAGGAACCCAAGAAATTCAATATTCTCATTTGTAAAGACAACTGGTAAAA
+CATTTTCAAATCAAAAAATTATTTTTTTTGCCCTCAAAATTGATCTCCGA
+ATACTATAAAAAAGAAAACTATAAAAAGTGGCGAAAATTCGAAATTTTTT
+AACCCCTCTAAAATGGTTCATTTTAGTTGTCTAATGATACAACAAAGTAG
+ACATAGTTCTACAATATCTGATAAATACTTGAAAAGTCTAAAAACAAAAG
+TTTTTTCGTTTTTTTAACGGATTTTTAAAATCCAGAAGAACGAAAAAAAA
+TTTTTTTAAGAGAATAGAGTAAACTAATCATGTTCGAGCAAAAAAATCCG
+ACTTAGAATATGAACGGACCCAAGTGTATCATAATTATTTTAATTTCTGT
+GTATCAGAATTATTTTAGTTTCCTTAGTGTGATTCCCAAACTGCTTAAAT
+TCTAGGAAATATTTCTTTACTGGAACACTCTTAGCCACTGTACGCTGCCG
+AACGAATAATAAGAGAATACAGAACACCAATTATGCCCGAGAAAAAGATC
+CTACTCAGAATATAAACATAGTCAAATTTATCGGATGTATAAAGATTCCC
+GAAGACACTTTCCAATTACCCAAATTGTTCATATTCTAAATCAAATTCTC
+TTACTAGAACGCTCTTGGCCAATGTACGCAGCCGAACGTATCATAAGTGA
+ATACAGAACACCAATTATGCCCGAGAAAAAGATCCTACTCAGAATATAAA
+CATAGTCAAATTTATCGGATGTATAAAGATTCCCGAAGACACTTTCCAAT
+TACCCAAATTGTTCATATTCTAAATGAAATTCTTTTACTAGAACACTCTT
+GGCCAATGTACGCAGCCGAACGTATCATAAGTGAATACAGAACACCAATT
+ATGCCCGAGAAAAAGATCCTACTCAGAATATAAACATAGTTAAATTTATT
+GGATGTATAAAGATTCCCGAAGACACTTTCCAATTACCCAAATTGTTCAT
+ATTCTAAATGAAATTCTCTTACTAGAACACTCTTGGCCAATGTACGCAGC
+CGAACGTATCATAAGTGAATACAGAACACCAATTATGCCCGAGAAAAAGA
+TCCTACTCAGAATATAAACATAGTCGAATTTATCGGATGTATAAAGATTC
+CCGAAGACACTTTCCAATTACCCAAATTGTTCATATTCTAAATGAAATTC
+TCTTACTAGAACACTCTTGGCCAATGTACGCAGCCGAACGTATCATAAGT
+GAATACAGAACACCAATTATGCCCGAGAAAAAGATCCTACTCAGAATATA
+AACATAGTTAAATTTATTGGATGTATAAAGATTCCCGAAGACACTTTCCA
+ATTACCCAAATTGTTCATATTCTAAATGAAATTCTCTTACTAGAACACTC
+TTGGCCAATGTACGCAGCCGAACGTATCATAAGTGAATACAGAACACCAA
+TTATGCCCGAGAAAAAGATCCTACTCAGAATATAAACATAGTCGAATTTA
+TCGGATGTATAAAGATTCCCGAAGACACTTTCCAATTACCCAAATTGTTC
+ATATTCTAAATGAAATTCTCTTACTAGAACACTCTTGGCCAATGTACGCA
+GCCGAACGTATCATAAGTGAATACAGAACACCAATTATGCCCGAGAAAAA
+GATCCTACTCAGAATATAAACATATTCGAATTTAACGGATGTATAAAGAT
+TCCCGAAGACACTTTCCAATTACCCAAATTGTTCATATTCTAAATGAAAT
+TCTCTTACTAGAACACTCTTGGCCAATGTACGCAGCCGAACGTATCATAA
+GTGAATACAGAACACCAATTATGCCCGGGAAAAAGATCCTACTCAGAATA
+TAAACATATTCGAATTTATCGGATGTATAAAGATTCCCGAAGACACTTTC
+CAATTACCCAAATTGTTCATATTCTAAATGAAATTCTCTTACTAGAACAC
+TCTTGGCCAATGTACGCAGCCGAACGTATCATAAGTGAATACAGAACACC
+AATTATGCCCGAGAAAAAGATCCTACTCAGAATATAAACATAGTCAAATT
+TATCGGATGTATAAAGATTCCCGAAGACACTTTCCAATTACCCAAATTGT
+TCATATTCTAAATGAAATTCTCTTACTAGAACACTCTTGGCCAATGTACG
+CAGCCTAACGTATCATAAGTGAATACAGAACACCAATTATGCCCGAGAAA
+AAGATCCAACTCAGAATAAAAACATATTCGAATTTACCGGATGTATAAAG
+ATTCCCGAAGACACTTTCCAATTACCCAAATTGTTCATATTCTGAATGAA
+ATTCTCTTACTAGAACACTCTTGGCCAATGTACGCAGCCGAACGTATCAT
+AAGTGAATACAGAACACCAATTATGCCCGAGAAAAAGATCCTACTCAGAA
+TATAAACATAGTCGAATTTATCGAATGTATAAAGATTCCCGAAGACACTT
+TCCAATTACCCAAATTGTTCATATTCTAAATGAAATTCTCTTACTAGAAC
+ACTCTTGGCCAATGTACGCAGCCGAACGTATCATAAGTGAATACAGAACA
+CCAATTATGCCCGAGAAAAAGATCCTACTCAGAATATAAACATATTCGAA
+TTTAACGGATGTATAAAGATTCCCGAAGACACTTTCCAATTACCCAAATT
+GTTCATATTCTAAATGAAATTCTCTTACTAGAACACTCTTGGCCAATGTA
+CGCAGCCGAACGTATCATAAGTGAATACAGAACACCAATTATGCCCGGGA
+AAAAGATCCTACTCAGAATATAAACATATTCGAATTTATCGGATGTATAA
+AGATTCCCGAAGACACTTTCCAATTACCCAAATTGTTCATATTCTAAATG
+AAATTCTCTTACTAGAACACTCTTGGCCAATGTACGCAGCCGAACGTATC
+ATAAGTGAATACAGAACACCAATTATGCCCGAGAAAAAGATCCAACTCAG
+AATATAAACATATTCGAATTTATCGGATGTATAAAGATTCCCGAAGACAC
+TTTCCAATTACCCAAATTGTTCATATTCTAAATGAAATTCTCTTACTAGA
+ACACTCTTGGCCAATGTACGCAGCCGAACGTATCATAAGTGAATACAGAA
+CACCAATCATGATCGAGCAAAAAGATCCGATTCAGAATATAAACATATTC
+GAATTTATCGGATGTATAAAGATTCCCTATTGGGAAGTGGAGCAATCCAC
+GACTGGTTTATCGGCCACAGTCCCCGGCTAGGACATGGCTTATATTATTG
+GGCCAAGGGGAGCACCACCAGGCAGTGTACCTGACTCCCAGATCAGCAGT
+ACATAGCACTTGAAGAATGGATCGTCCTTTAATCTTTTAATCTTTTAAAA
+AGAATCGAAGGAACTCTCATCGGGTCATGTGGTTGTGGGGACAAAGAGGG
+AGGCTTACATCAATACCAAATACCTGTGGTAGATCACAATACCTGTGGTA
+GATCACACCCTATCCACAAAGAAAATCTGTGGACGTCCTCAAAGGAGGCC
+GCCCGCGCCCTTGAGCTGGCCAACAAACCCTTCGAGCTGGGTGGAGGAAT
+ACTCCAGCCGAGCGACTGAAAACGGCGGTAACGCCACGTTGTCGCACAAT
+AACAACAAAAAAGCCCGCGGGCCCCAAGAAGCTCAAGAAGCCCACGGCTT
+AATTTTCAAATCAATTACCTTACTATGAATCTCCTTTTTGCTCTACGAGT
+CGTCGTTGATGTCATCCTTCCGTCCAACCTCCGTCAAACAGTCCATCTGA
+CCATCCGTCCAACCAACATGTGGTGGAGTGTCCAACGCATCTGAAATTGA
+AAAATATTTATATCTGATTTTTTAAATGGAACCATTTACAAAAAACATAA
+ACGGAAAACGCTTAGCAAAAAAACAAACAATTAGTATTTAGAAAAACGGA
+GACAAATGCTCTCGCGATCTTATTTATATTAATTTTCCAGTCGATTGCAA
+GGCATCTGCTCCCACGGGTTTATATAAAATTGTGTAACTAATTTTAAACT
+TCTCTTGAAACCTTTCAACCAGTACTTTTCAAGAGTTTTTGGTAATTTTT
+CGATTTTTCAGAAATTTCAAAAAAACGGCGAAATTCCACTCAGAACCCTC
+ATTAATATTTCACTAGTCCAGCACACTAACCCAAAAAATTATTTTTTTTT
+TGAACTACAGTAATCCTACAAAATTGCTACAGTACTATTACGGGACCATA
+ACAAAATTTTGATAATGCGTATTGCGCAACATATATGACGCGCAGAATAT
+CTTGTAACGAAAACTACAGTAATAATTTGAATGACTACTGTAGCGTTTGT
+GTCGATTTACGGGCTCAATTTTCGTAATGTTACACGACACATTTTTTTGA
+CAAATGCAAAAAAGTGTGCGCCTTCAAATTAAAAAAAAATTTGATTTTTG
+TTGCCGGCTTTTAACACATCGAAAAAATAAAAGAAACGAAAGTTTGTAAT
+TACAGTACTCCTCTTAAACGCGAACACCTTTTCGCTTTTCAGAAAAACTT
+GCGCCGTTTCGAAACCGGGTACTATACTTTTATATTAAAATCGATTAAAA
+ATCGCGAAATTTTGCGGTGGAGCATATGTCAAATTGCAACTCGAAAAGAA
+AAAATCTGAAAATGCATGCTGTGAAAAAAAAAGCAGCAGTACTCCAAGTC
+ACCCATTGGAAAGAATGACTGAAAATTGAAAACAATTCTTCACTTTGAGC
+GAAAAAATGCCGCGTTGAATGAGAGAGGGACGAATCGAAATTTAAAAGGA
+GAAGATCAAAAAAAAATGTTTGTGGTAGGTCTGGAATCTTGCAAATTATC
+GTTTTAAAATCAATTTTTAACACTTTTATATCATAAAAATAGTTTTTCAT
+CAATCAATCGATTAAAATACCAACTCTCGAAAATTAACAGCTTTAACAGC
+GCCGTCTACTGATTTGAAATTGCAGTCGCTGCCGCTCAATTAAATGTTTT
+GCGCGTCAATTAAAATGCCTTGTACGCAGATGCGCGTCTCCTAAAAAATA
+AAAAGTTGTCCAATTTTATTGAAAACGGGTATTTAATTCATGTAAATATG
+CTGAATTTAGAAAATCTAGGTTTAACCTATCAAAAACTATAAAAAAGTGG
+CAAAAATGGGCAATTTATGGCAAAAATTCACAATTTTGAAACTCCTCTAA
+AATGGTTCATTTTATTGGTAGAAGAGGACTAAAAATTGATATCCGAACCC
+TAAAAAAATTGTCCTTTTTCAATATTCAGAAGAAAATTATGAAGTTATTT
+ACTTCCATTTTTCGATTGTACGGTAAATCAAAACTAAAGGTGGGCACGGT
+ATCTGATAAAGTTACGATCGTTCCAGGATCACGAAAATCGAATAATTACA
+CAGCCAGAGTTACATGAAACAGTGTTTGGGAAATTTAAAAATCAGTACAA
+GAAAACCTCAAAAAAAAAACAAAATTACAGGAAAAAACGGAAATTTTCAG
+TAAAAAATTATAGGGTATGTAAAATCGATAAAATATTTAAAATTCAATCG
+TATTCTCCGTTTTCGGCGTTCGGATCGTTCACTGGAAGTACGGGATGTCG
+AAGTTTGAAATTGAAGAATTCGCACCAACCGGCTGGAAGTAGATCGTGGG
+AGCTGCAAAAAATGTTCGTGGCCGCGAAAAAAATCGGTGGCCGATTTTTG
+TTTTTTCGCGGCCACGTTGTGACTAGACGGCGAAATAAAAATTTGTTTTT
+TGGTTTTTAGTGTTCAAAACTGTTGTTCTTGTTGAAAAACAATTTTTTCG
+AATTTTTTTTGTTTTTTCAACTAATTTTTTTTTCTGAAAATGCTTTTAGA
+ACAGTTCATTTTGTTTTTTTTTCAATTTTTTTCAGACACCCCTTACTCCA
+TATCATAAAGCTCGGAAAATTCGGAATCCCATCCCTGAAACTCGATGAGC
+ACCGTTCTACCGTGTACTTCTTCGACGGAGGCCGGTGATATCCAGTAGGT
+CTCGTTTTGGCCGACGGCTTCAAGGACACGACCGAACTGAAAAATATTGT
+TTTTTTTTTCAAAACCATTTTTTTTAGGAAAAAATTTTTATTGAAACGTT
+TTTTTTTTAATTTTAAAATTCCAAAAAAACGCAAAAGTGCAAAAAAACTT
+GAAAAAAATGTTCTCAATATTTTTTCCGACTCACAATCAAAGAAAATTTG
+AATCGAAAAAAATTAATTGTTTTCTTTTAAAATTTAAGGAAATTATTTTT
+CTAATTATTTCTTCCAAAAAAAAGTTTAAAAATAATAATTTTTCAAGTGT
+TTTTCAAGAGAAAATTAAAAAATTTCAAATTTCAAATTTTAATATACTTT
+TTATTTTAAAAACTTGTATAAATCTCCGAATTATATGGATTTTTTTGAAA
+AATAAAAAATTTTTTTATTGGAAAAAGAAATCTGATTTTTATAGTTTTTT
+TTTTTAATTTGAAAAATACGAATTCTATCACGGCAACTCAAAATTCTGAG
+AATGCGTACTGCCCAATATATTTGACGCGCAAAATATCTCGTAGCGAAAC
+TACAGTAATTCTTTAGATGACTACTGTAGCGCTTGTGTCGATTTACGGGT
+TCAGTTATTTAAATGACTTTATTTTTCGTATTATTTTCTTCATTTCAATT
+AATTTTAAAAATTGAGCCCATAAATCGACGGTACCGTAGTCATTTCAGGA
+ATTACTGTAGTTTTCGCTACGAGATACTTTGCGCGTCAAATATGTTGTGT
+AGTACGCATTTTCAGAATTTTGAGCTGCCGTGATAGAATTCGTATTTTTC
+AAATTAAAAAAAAACTATAAAAATCAGATTTATTTTTCCAATAAAATTCG
+TCTAATTTATAAAAAAAAATAAAAATAAAAATTGAACAACGCTGAAAAAT
+CCCAGATTTTTTTTTCTTATTTTTTGAAAAAAAAAACTTTTTTTGGAATT
+TTAAATTACATAATTTTTTTGGTTCAATCAATTTTTTGGTTAAAAAGCGT
+TTTTTTTTCCTTCAAAAAAGCACCTCAAACATGTGCCTTCTCTCCTTGCT
+CGGCAACGGCCTAAGCATCTCATCAGGAATTTTTTCCGCCTGCTTCTCCT
+TCAAATACCCTTCCCACTTGAATTTCCCGGGCTCAGTGCCTGCAAGCCGA
+TCCAGCTTGATTCCGAACTTCTCAGCATAGCCGACAGGATGCATAAAATG
+ATTATCAATATGAATTGGGAAGGATTCATCGTCCGATTCTGTCTCATCAG
+GTGAAATAATTAAAAATCCAGGCGTTTTGCATATTTTTCGAATTGTTGCG
+ACGCAAAATGACTGGCGTAGGTCGCTGAGTGGATCCAAAAGTTCAAATTT
+TTGGCCGACTTTTAATAAATTTAATTTTTCAGCTGAAATGTCAGGTTTCC
+CAGCAAAAAGTTGCTCGAAAGTGACGTCATCTTTATGATAACTTCCAGAA
+CCTTCTGCGATCCGTCTGGAATGTTCCAAATAACCTTCCGTAGCCTTAGT
+CCGTAATCCATTAATCATTGCAAATCCGACTGGAAACAGGAAGAAGCTCG
+ACTCATCCACCCAAAACTCGACGTTTTCATGCTGAACCTGCCGATCTTTG
+GCCTCTACGGAAGGAAGATCTTCGGGATAATCCTGAGCGGTGACCATGAC
+CATCAGACGGCGGCCAAGGATCCTGAGGATCCGTGCGACACGGATTTCTG
+TTGGCTCCAAGTAGTTGAGTAGCTCGACGCGTTGATTCAGCCGGAAACGA
+GATGGGCGGTGGGCAAGGTGGCGGAGTTGGTCGAAGATTTTTGGCTCAGA
+GATTCGATTTTCGTGCAGCTCGGCTTGAAATTCCTGCAGGAAAATTTTTT
+TAGGAAATGGGAAAATCAGAAGGGTTTTTTGGAGTTTTTTTTCAGTATTA
+TTTTTTTTGTTGTTTTTTTGAGGCTTTGTTAAAGTTTTTAGGTGAATTTT
+TTTTGTTGATATTTTTGGTTTGTTTAAGAATAAATCATTTTTTGAAAAAA
+ATTCGTTTTTATATTTTCGGTTTTTTGCTGGTTTAGTTAAAAGTTTTTTT
+TTCGGATTTTCAGGTTTTTTGACAAAAATTGATTTTTTTTTTGGTGTATT
+TCTTAGGTTTTCGGGTTTTTTTTTTGGTTTTTGACGAAAAATTTATTTTA
+AAAAAAACGGACTTTTTTGCAAAAAATATGGGGTTTCTTAAAAAAAAAAA
+TTTCAATTTTTTTTGTTGGATAAAATTAAAGTTTCTTTTATGGTTGATTT
+TTCGCCTTTTTTCACATTCTCCACCAGAAAAAACATGAAAAAAACCAGAA
+ATGAGTAGTTTTGAGCAATTTTCAGGCAGTTTTTCCGCTCAGAAAATAAT
+TTTGGCCGGATTTTCATGGTTTCTCACATCCAGAATCTCCTCTGTTGGCC
+GTGGTACGGGCGGTGCAGGCGTAGATCCACGTCGCCAAAATTTCGGGCAT
+TGCATCGGTTTCAGCAAGCTCAGTGGCCTGTATTGAAGCCATTTCATCGC
+TGGATCCTGCTTGAGACCGCTGAAATTTCGCGTTTTTTTTTGGAAATTTT
+GTTGAAAAATAACCTTCCAATATCGAAAATATCCTCTGAAAGCATATGAA
+ACCAGCAGGGTCTTCTATTAAGTTCCCCCACAAATTTAATTGCCACGTAG
+AAGCCGCAGACAGCAGTCACCTCGCCGAACCAGCGGATTTCTGGAGATTT
+AGTGGTTATAGAAGGATCCAGAGACGGTCGGACGACTACTTCTAGCTGAA
+AACATTAAGATTATGGCTTTAAAGTTTTTTAAAAGAAAAACCAACTCGAA
+ATCCAGGTTTTAGGTGCTGATTTAGCTTTTCCAGCGGCAAACAACCCTCC
+AGCGCCTCGACAGGTAAAAATTGAGTATTTCCATCATAATTACATCGGAG
+TTCATCTGACCATGTGAATGTTCCTTCAATTTGTGGCTTTGGAATCCGCT
+GGGCGATTTTCTCAACTGGATTTCTTCGACGATAGAATAGCCGTTCTTCG
+GTGAAATATCGGTATTCTGCTTCTTCAAGTTTGTAATTATATTGACGCTG
+AAAGTAATAAATTATGTTTTTCGATAAAAATGCTTTTAAAATTACCTTTT
+TATTCGAAAAATTCATTGATTTTAATTAAAAATCTATTTAAATTGTTTAA
+ATTAAAAAGTTCCAAGCTTCTGTAGTTATCGCGTCGAGACCCAACACACT
+AATTACCACATGCGCCTTTATATAAATTTTAAGAAAATCAACATTTTAAA
+AGATTTTTACAGTTTTTTTGTCGTTAAATTTTTCGAAAAAATGATTTAAA
+CTCACAGTAAACTTGTTTGAAACTTGAATATTAAAATTTCACAGTCAATG
+GGTTAAATTTCAAGACTTTCCCACTGATGATACGGTAGGCGCGAAGTACG
+GTAGTTTGTTTTGTTTTTTTTTATTTTGCCGCCGAGTGATTCAAATTTGA
+ATTTATATCATCCGATTTTTTGATTTTTTCCTCAATATTTCTCGATTTTT
+CAGCTTTCAGTGTGATTTTCCAAGAGCCGTAGCTCGACCAGACGACGGAG
+AGCCTGAGGCTGGTCGCCAGAAGCACTATGAAGTGTGGGTTTTTTTTAAA
+GCATAATTTGCATTAATCTTCTAATATTTTAGCCACCCCACACCGTCCAC
+GAACAAACTCCGAATCGAAGCTCGGGGCTCGCGAGCAGCTTCTCCGGGAC
+TCTATACGAGTGGGTTTAAGTTCTTAATTTCAAATTTCACTCATTTAAAA
+ATTTTATTTTTTAGCTTCAAGTAGCTTCGGAGCCGTACGTCCACATGACA
+AAGGAATCCACGTGGGACGAGGCGAAAAAACTGGCGATCAGTCTTGAAAA
+GAAGCCGGACATTGTCCGTAAAGCGATATACAATCGTCGTCGCTTCGTCA
+ATGAAAAGATAAAAAGTGCGCTGGTCAAGCGCGAAATCATCGACCCAAGA
+AGCCCGGCAATCCATGAAATAGCAGTGGCGGCGGAGGTATTTTAAAAGAA
+AATCAGACAAATTTAATATCTAATTATTCCCCATTTTCTTGCAGACAATC
+GCCATAAACGTTGTGCACTTCTTGGAGACTCATCACGCAAAAATACTCGC
+TGAAATCAAAGCGGCCGCCGCTGGAGCCGGCGCCCAGCTCCGAACTGCAT
+GAATTAATTCAAATTAATATTTTTAAACTCATTTTTCACACAAATAATCA
+TTCATGTGTCCATTTTTCACTCTCGAAACCCATATACCCTCACTCTAAAT
+ATCAATATAATGCACATTTCTCATAGTTTTAATCTGCCCTTACCAATTAA
+ATCTTACCAATTTTCCGCCATGATCCCTTTTTCCATTTTGAATAAAATTC
+GACGACGATTTTTCCATTAAAACAAGAAATATATAAATAGATTCAAAAGT
+GGCGCTTGTGTCGCTCAGCGGTCTCCTCCACTTGCACACTATCTCACCGC
+GGCCTTCCAATTACTCGTCCATTTTCCAGCTGTAAAAAGTTTATAAAAAC
+TGAAATAAATGCAATTTTCAGCAGAAAATCGCTGAAAATGCGGCAAATCG
+TCGAGCTAAAGTCACTTTTGACTTCGGAGCCAATTAAAGCCATCGAGCTC
+TTCGATAGGCTCGTTGGACAAGGTTTGAGCCGAAAATCTAAACTTTTAAG
+CTGAGATTTCTTTTAAAAATCCCTTCCAGATGCCGACACAATCACCCAAG
+AAGCCTGTGGAACCCTCGCCAACTATATCCGGCATTCCAGTGTTTTTAAG
+CGACGGCTTCTGTTCACGGAGCTCCAAAAATGCTCGTTTTTTGCGAAATT
+GTGCATTTCGTTTCAATTTCACAGCTTTGAAGACACAGTTTTTCCGCGAA
+AATTGATTTTCGAACGATTCAGCGTGTTTTGCGGTGAACTGGAAAAGGAC
+AAGCCACGTGGGTTTTCATTTATTGAAAATTGAAAAGATTTTTGCAAAAA
+ATCATAAAATTTAATGTAAAACTGAACAAAACTCGATTTTTAACCGAACC
+TTTTTGTTTTTTCCGTGAAAAAATCGGTTTTCCAAGTTTTTCGAACATTT
+TCCGAAAAAAAATTACGCAAAAAAAACGATTTTCAAGTAACAAATCCGGA
+AAAATCAAACTTAAATATTTTCGGAAAATTTCATAATTTTCTTCAAATCT
+CTGTAAAAAGTAGATTCGATTTCTGGGAAATTTGAATTTATGTCATTTCT
+TTAAAAGCGCATGCTCTTTTGTAGGGTCTCGCAACGAATTATTCAATTTA
+AACTTTGAAATTCGCGCCGAAATTTGGGTCTCGGCGCGATTTTTCGAAAA
+ATAAATGAAAAATATGTACTATTAATTTTTTCTTGAAAATTATTGATTTT
+TCAGATCACCGGCACCACGTCACCGCTGTCGGATCGAATCGTTTCTTCAA
+TTTGGGACTACTTTCCGATGGAAGCCCCGTCTCAGAACCCCGACTGGTCC
+CCGTGCCACGTGTAATTCAAATCGAGATGACAAATACACACACAATATTT
+TTGACTGCTGAAAATCAGATTTACGGCTGCGGAAAAGCTTCATCTTTTTT
+GCCGGATAAAACGGAGGAGACGGACGGTGGTTATGTGGCACTGCCCACTT
+TGGTAGAAATTCCAAAAGTTACTGGATACGTGGCAGCTGTGAAGGTGTTC
+GATGGAGGATCACAGTTTTTGATTGGCGGCAAAGTACGGTTCTAGAAAAT
+TGGTGGCCGAGTATTTTTTCGCGGCCACATGGCGATTTTCTACACGAAAA
+GTTGTGTAAAAGACAAAAAGGTGTGCGCCTTCAGGGATTACTGTAGCTGA
+AGTTTTTCATAGATTTTTTTTTTGGCTTTAAAAAAATCCTTAAAGGTGCA
+TTTTCGTGTCGAGACCTTGTTGTATTATTTTGCTAATTTTGCTTAAAAAG
+TACAGTACCAGGTCTCGACACGAATAGTTTTGATAAATGCAAAAATGTGT
+GCGCCTTTAAGGATTACTGTAGTAAAAAATAAGAATCCCTTTTGGAAAAT
+TTGATAATTTTGTGAAGAAAAATAGATAATTCTTTGAAAATGAATAATTT
+TTTGGAAAAATCTTTTTTTCTTATTTTTCTAGACGTACACCTTTATTTCA
+TTAAAAAATTGTCGCGCCGAGACCTGATACCGTATTTTTGAGCGCAAAAT
+CGTGCCGAGACCCAAATTCGTGAATTCAAATTTTCAGTGGTATTGTGTTG
+GAAAATGTTCGATTTCCGGAGAAACGCGACGAATTTCGTCGAATTGTTTT
+GTTCTGGTAGAGGAGGAAAACGAGGAGAAATTGGAGAAAATGACGAAAAA
+TATCGATTTTTACGTGGCAAATGTGCCGATTGAGGAAAGGATTGTGAAGG
+TGGATTTTTTTTTTCAAAAATTTGAAAACAAAAAAACTAAAAAAAAAAAT
+TTTAATCTTAGTTTCTAGAATTCAAGCCAGTTATAATAATTTTTAAACTA
+AAAATTGCATCTTCCGAATTTTCAAGATTTTTTTTTCTGAAAATCGTTTA
+AAAAAATATCTTGAAAAATCAAAATTTCAAAAAAAACAAAACTTGAAAAA
+AAAAACGTCTTTAGCGGTATTTTTTCTATAATTTTTCAATTTTTTTCAGC
+TTAAAAATCATAGAAAATCGTAATTTTTTGACATTTCTTCCAGGTATATC
+TAAAAATGGACCAAAACGAGATTCTGTGGGATAGAACGAGCGATTTCTCA
+GCGGAAAAGCCGATTTCCTTCATAATCAATGGATTTCCACAAATGGCAAT
+TTTCGAATCATTTCAACTTTTAAATGATGGAACTATTTATGCTGCGAGAA
+ATTCACTTTTCAAAGGAAAATTGGAGCTATGGAAGAACAAAGATGACGGG
+TTTAAAGTGAAAAGCGGGACTGTTTTGGAGCATTTTGACACGAAATATAC
+ACTTATTGCACTGATGGAAGAGGTTCCCGGTACTATTGGAACAGAGTTTT
+TCAAAGTTTCACCAGATGGGCAGAATTTGATTATGAAGGTTCATTTTGTT
+TGGAATTTGAAGGAATTCGACCTTAAAAATATAAAAAATTGCACTGATGA
+TGTTATGGATTTTTTTTTCAGAAAAAAAAAAACGAAAAATTGAATGCTAA
+ATGACAGAAAATATGCCCCTGTAACATTTTTTTTTTGAATTTTCTAAATT
+TTAAATTATTTTTTTCAGTTTTGCGCAAATCAAAGAAACGGCCGAATTAA
+ATTTGAATTCCCGCGCAAAAGAGTGACGTCATTTTTTTTTTCCCGTTTTC
+CGGATGTATTATTAGGTTTTTATTTTAAACACAGTTTGTCAATTTTTCAG
+ACATTTTTTTTTAAACTTGATAACCCGAAAAAAGTGGCCTAGAAATCGGC
+TTTACAATTTTTTTTTTAAATCGACAAACTGTGTTTCAAATTATGAAACA
+AGGAAAAAACGAAGAAAAACTTATAGCCGGAAAACGCGAAAATGTCGAAA
+ATGACGTCACTAAATTGCGCGGGAAAAAATATAGAATTTTTTTTTAATTA
+ACAGCTATATTGAATCATTAGGGCTTGTTCTCCGTCAAAAAATTTCTCGA
+AAAAATTGATTTTTCGTTTTTTTTTGGAAAATCGAAAAATTTTGTTTCTC
+AAAAAAAACAAAATTGGAATTTTTATTAAAAAATTATTTTAATCCAACAA
+AAAAAACTAAAATTTTTTGCAAAATTTAAAAATTCATAAAACATTTAAAA
+AAATTTTTTAAAAGTTATATTGGGACTGTATTCTAATACTTGGACTAAAA
+AAACCCACATTTGACAAAAAATTCAATTTAAAATGAATATTTTCAGATGG
+GCTACCAAAACGAACAGAAAACCGAGAAATTCGAATTCGAGTCTCCCAAA
+ATTCACAAAATCATCAAAAATCGTGAAGTACAATGTGATCCAGTTGATAT
+TCCGTTAGACTCGACTATTCATTTTCATCAAAATTATAATCAAGAAGTAT
+TGAAATTTCAATCGAATCGATTATTATTTCAATGGATTTATCCGAATTAT
+TTGTTTCAAAACGATGGAGATGTACATTTTTCAATTGAACAATTGGAGAC
+TGTATTTGCTGTGGATTTGGAGAATTTGGAATTGTGAGGGTTTCTTTTAT
+TAATTAAAATTTTTTTAAGTGGAAAAATTTTGGTTTTCTTTTCAGAAATT
+ATTGTAATGTTGTAACTAAATATTACGGGAACACGAAATTCTAAGAATGC
+GTATTGCACAACACATTTGACGCGCAAAATATCTCGTAGCGAAAACTACA
+GTACTTCCTTTAATGACTACTGTAGCGCTCGTGTCGTTTTACAAGCTCAA
+TTTTTTAATACTTTAAATTAAAACTTTTACTTTAAATTTTAAAAAAATTC
+GTCTTATTTTTTAATTTTTGCTTTATTCCAATATTCTGTCGATAAATAAA
+TCATTTTAATAAATTTAGAAAATTGAGCCCGTAAATCGACATGCGCTACA
+GTATCCATTTAAAGAATTACTGTAGTTTTCGCTACGAGATACTTTGCGCG
+TCAAATATGTTGCGCCGTACGCATTCTCAGAGTTTTGTGTTCCCGTAATA
+TAGAAAATTAGAAGTATGTTAAAATTTTTAAAAAGTATTTTTTTTGGACT
+TTTACCCAAAGATTTTTTTTTGCAAATTTTTAGTGAAAATTATTATTTTT
+TTCAATTCACGCTAAAATTTATTAAAAATTTAAATAATTTTAGACTGTAT
+TCTATACAATCAAAAAACAACAAACATCAATAAAATTTTCAATGAGTTTA
+AAATTTTTTTGAATTTTTTAAAACTTTTCTTCGTTGACAAAACGTTCACA
+AAACTTGAAAAAATATATTTCAAATTAATACTTAAAAATTCAAACAAAAA
+ATTTTTAAAATTTTTCAGCCCGAAATACCAACCTATATCACCAGAAGAAT
+TCGTTCCCACCGACACTTCTCCCTCCGATATCTGGTATTTAAAATCCAGT
+GAAAAATTGAAAATCCCTTGTCACAAGTACCTTCTCCTACTACATTCACG
+TCAAATTGGCGCGATGCAGAGATTTCATTCAAATTATGGGAATTTCGGCG
+ATTTTAAGGATGGTAAATCTGAAAATGAAGTGGAAATTGAAGCGAATGCT
+AGTGTTGAAACTGTGAAAAATGCGCTGAGAGGGATGATCAATATTCGAAC
+TCTTTTCAAAATTAAGACTATTGAGGTAATTGGATTTTTGGTGAAATTTG
+AAATGAAAAAATATTTATAAAAATTGAATTTTTTTTCAAATTTTTTTTTC
+AGTCACCATAAGTCAATTTTCCATTAGATAAAAATCGATACTTTTTCTAA
+ATGCGATAAAAATTGGAAATTCTATAAATTCCGGAAAAATCGATTGATTT
+CAAAAAATCGATAATTTCCGGAAAATTGATAAATTCCAGAAAATCGGTAA
+TTTCCGGAAAAATCGATAATTACCGGGAAAACCAATTAATTTCCAGAAAA
+ATCGGTAATTTCCGGAAAAATCGATTGATTAAAAAAGTCAATAATTTCCG
+GAAAATTGATAATATCTAGAAAAATCATTAAATTCAGGAAAAATCGATAA
+ATTCCAAAAAAAAATCGATAATATCCTGAAAAGTGAATAAATTCCTAAAA
+ATCGATGAATTTCATCAATTCCGGGAATATTTTTTAAATTTAAACTTTAA
+AAAATATTTTTTTAAATCTTTAATCCTTATCTATTTTATTCAAAAAAAAA
+CTGATCAAAAAAATTTTTTTTTTTCAAAAATTCAATATTTTTGCAGTTAA
+TCGAATGCATCAACTTCTACGATTATCATTTAATGGATGAAATGTTCAAT
+GATTCAATGCATATTCTAATGGAAACAATCACTGAATTCACACTTCCATT
+TCTCTACGAATTATTCTATTCGTTTGAGGAAAAAGTGTTGGAGGGACTTT
+TGCAGAGGAAATATTTGATTTCTAACTCAATTTCCAGTGTTTTACCGCCA
+AAGGAGCTTCTTGTACGGTAAGTGAGTTAAGAAATGGAAAAAAACACATT
+TTTGCTACTGTTGGAATTTTTTTTATTTCACAAATATATTTTTTTTCATT
+TTAAAGTTAAGTAGGAGTTTATCAACTTTTCTGGATTTCATCAATTTTTC
+CGAAATATTTTGATTTTCCCGGAATTTCTGTGTTTTTCAGGAAAAAAACC
+CCAGAAAACTAACAAAAAGAATTAGCAAAAATGACCTAAAAACCGTAAAA
+CTATGTATCCCAACTTGTCCACGTGTAGTACAAAAAACCGATGTGCACCA
+ACAAGAATTTTTGCAAAAGCTATTTTTCCATTCAAAACTGCGCCCCAAAC
+AGTTGAAATTTTATAGAAAATTTTCGAAATTCGCTTCTCCGAAAATAAAA
+ATCTCAGATCCGCCCATTTCTTGGCTCTTCCAGATTCGCTGAAAAACTGG
+ACACCGATTGCCGCCGACACCACACATTAAAAGTTCCGTCGAAATTCAAA
+AATCTAGAAAATCTGAGCACCTATGAGCCCGAGTACATTGTCAAATATTT
+TCTGAATCTCGACCAAGATTCGGAGGATGTGACGTGGCGATCGATACGTC
+ACGAATTCCACGACACACTTGACACGTGGCACGCGGAAGCTGTGAAGAAG
+AGAGATGAGAGACGTATGCACGGAGCAACACGGAGCAGAACGAGTAGTAT
+TCGGAAGGAGAGCTTTACGAAAATTCAAAATGTTTCGATGACGTCATCGC
+CGGTAGGAATATCGATTTTTATGTATCGAATTTACTGGAAAACTATCAAA
+AGTTTAGGAAAAATATCGATTTTCCTGAAATTTATCGATTTTCCTGAAAT
+TTATCGATTTTCCTGAAATTTATCGATTTTCCTGAAATTTATCGATTTTT
+CTGGAATTTATCGATTTTTCTGGAATTTATCGATTTTCCTGAAATTTATC
+AATTTTTCTGGAATTTATCGATTTTTCTGGAATTTATCGATTTTTCTGGA
+ATTTATCGATTTTTCTGGAATTTATCGATTTTTCTGGAATTTATCGATTT
+TTCTGGAATATATCGATTTTTCTGGAATTTATCGATTTTTCTGGAATTTA
+TCGATTTTTCTGGAATTTATCGATTTTTCTGGAATATATCGATTTTCCTG
+AAATTTATCGATTTTTCTGGAATTTATCGATTTTCCTGAAATTTATCAAT
+TTTTCTGGAATTTATCGATTTTTCTGGAATTTATCGATTTTTCTGGAATT
+TATCGATTTTTCTGGAATTTATCGATTTTTCTGGAATATATCGATTTTTC
+TGGAATTCATCGATTTTTCTGGAATTCATCGAGTTTTCCGAGATTTATCG
+ATTTTTCTGGAAATTTTACTCCCCAAAAATTTAACAATATATCGTGCCGA
+GACACGAAAAACTCTAAAAATTACAGATTCCAATCGGAGGCGGCCGCTCG
+AAACCCGAAAGTTTCTCAAAATCAATCAATAGTCCTGTCATTCAATCGCC
+ACTCTCTCCCTCACCAATCAAAGGAATGCCAAAGGTAATCGTGTCGAGAC
+CCACCACGCCACCTGCGCCTTTAAATTCCACGTTTTGTAGTCCCGCCACG
+ATAGTATTTCCAATTCACTGGACGATTTTCCTGAAATGAGCATTTCACCG
+TCCCCCTCGACACCGAAATCCTCTTCCGGTGGCGGTCGCTTCGCACCAAA
+AGGAACTCGATTTAAAAAGGATTTCGAAATTCTCGTGAAACCTTCCCAGT
+CACCACAGAATCCGTGGAAAATGGGCGGAGCTTCCGCGTCGATTCGCGAA
+GAAATTGATCCGCAGGAGATCCGATTCGACGAAGTTGTGAAGAAGGAACA
+GAAATTGCAGACTAATATACGTGCGTCACTTGAAATTTTGGAAAAATCGA
+TAATTTTCAAAAAAATCGACCTTTTTTTGGAAATTATCGATTATTCTTGA
+AAATTATCGATTATTTTAAAAAATTATCGAATTTTCTGAAAAGGATCGAT
+TTTTTCGGAAAAAGTTTCGATTTTCTCGAAAAATAACGACTTTTTTTTTG
+AAAATTATCGATTTTTAAAGAAATTATCTATTTTTTTGGAATTTATCGAT
+TTTTTTTAGGAAATTATCGATTTTTTTAAGGAAATTATCGATTTTTTTAA
+GGAAATTATCGATTTTTTTGGAATTTATCGATTTTTTTTAGGAAAAAGTT
+TCGATTTTTCTCGAAAAATAACGACTTTTTAAAAAAAATTATCGATTTTT
+AAAGAAATTATCTATTTTTTTGGAAATTATCGATTTTTTTTGAAAATCAT
+CGATTTTTAAGGAAATTATCGATTTTTTTGGAATTTATCGATTTTTTTAG
+GAAATTATCGATTTTTTTGAAATTTATCGATTTTTTTAGGAAATTATAGA
+TTTTTTCTGAAAAATTATCGATTTCTCAAAGGAAAAGTATCGATTTTTGG
+AAATTATCGATTTTTAAGGAAATTATCGATTTTTCAAAAGAAGAGTATGG
+ATTTTTTGAAACTATCCATTTTTCTTTTAATTATTGATTTTTTTCCTGAA
+AAATTATCGATTTCTCGATGGAAAAATATCGATTTTTCTGAAAATTATCG
+ATATTCTTTTGGAAATTATCGATTATTCTAAAAAAAATTATCGATTTTGC
+AGGAAATTCTCGATTTTTAAAATAAAAACAGCGATTTTTTTTTTGAAAAT
+CATCGATTTTTAGGGAAATTATCGATTTTTCTGAAAATTATCGATTATTT
+CTTCAAAATTATCGATTTTTCGAAGAAAAGTATGGATTTTTGGAAACAAT
+CTATTTTTCTTCAAATTATTGATTTTTTTACCTGAAAAATTATCGATTTT
+TCTGAAAAAATATATAATACCACACATTAATTTCAGGAACCGGATTCAAA
+AAAGTGCAGCTTCTACCACACGTGGAGACGGAAGAGCTCGCCGGAGCTCA
+AATTTTGGAGGTTTTTCGACGAGAACTTCACGATGAGGCGCTCATATGTG
+TAGGAATTTGTGATGGTTTTTTTCTCAAAAATTTGAAATTTTTCAGGTGG
+AACTGGTGATGAGCGACGATTTGGAGGTGGAAAACGAGCAGATCATCTGG
+GGAAACATGCCGGGACTTGTTCGGCGTTAAATTTTAAATTTTTGATTTTT
+TTTTTTCTTGTAACTTGCATTTTTTGTTTAATTTAGTGTTTTCGGTGTTT
+TTTGTTGAAATTTTCGGGTTTTTAATATTCAAAAATTAATTAAATTATTA
+TAAAATAAATGCATTTAGAAATGCGGTATAAATTGAAAATTTTCAAAAAC
+CATCTCCCCGAATCCAGTGGTTTAGGATGAAAATCGTGGAAATCGAGCCG
+AACGAGAGAATTCCGAGTTGCCACGTGGGTCTGAAAATTGAGTGTATTTA
+ATTTTGGAAAATTTTGGAGATCTCTTACATTTTCTCAAAAATCCATAGCT
+TTTTCCCATTTTTTTGTTGCTGGATCATTTTCAGCTCTTCGGTTATATCG
+CAGACTTTGAAGCAAGGGTCTTCCGGGAGAATTTCCTGAACATTTGAAGT
+TTTTGGGTGAAAAAAAAGCTTTTTTAAAAGATTTTTTGGTATTTTCAAAT
+AATATCGGAAATTTGCGTTTAAATTTTTTTTTTCAAAAAAGTGAATTTTT
+TCAAATTTTTCGAAAAATCGAAAAAAAAATTTTCGGGTTTCTGGAAATTT
+TAATTAAATGTGTTTATGATGATGAGAAAATATAGTTGACAAAATAATTT
+TTTCCGATTTGTCAATTTTTCAAAAAATTTGAAAACAATTTTTTCCATTT
+TTATTCCTGAACATAAAAAATTCGAAAAATTTTCGTTTTTAATAATATTT
+CGGAAAAATTTTGAATTTACCGTAGTTGTGTCATTTTTAAAGAAACTCAC
+AATATTTCTAATCGAAGTATGCATATTTTTTAAATGAATTTTTGGAAAAA
+TTTCAAACTTGTTTTTTGTTGAATTTTTCGATTTTCTTTCGTTTTTTTAA
+ACAGAACAAATTTTTCATCATCTTTTCTACAAACAAAACAAAAAAAACAA
+TTTTTGTTTTTAGAAAAGCGAGAAAAATTTCGAAAAATTATTTTAAAAGT
+TAGAAAAATATCAATTTTGAACGGAATTTTTTCAAAATTCGATTTTTTTG
+TTTATTTTTCTAATATGTTCAGTTTTTGGCCATTTTTTTTTTTAAAAAGT
+TTGCTTTCAAAAAATTTTAAATGAGAATTTAGATTTTTTAACGAGAAATG
+TTGAAATTGAGAAGAAAAAAAAAATCAATTTTAAATAGAAAAATTTTCTT
+TTTCTAACATTTTCAGTTTTCTCAAAATTCCAAAAACTCGTACATCCTCC
+TGACAAGTACAGTAATCCATTGGATCCAGATTCTCCTCTCCAACACTCGT
+TTCCCGAATTTTTTCGAACCAATTGTTCATTTTCATAAGAACCGAGCTCA
+TCGCAATCAATTTCCCGATATTTCCATCGTATTCCTCCGAAAATTGCTGA
+AGCCGATTCAAATTTCCAATATCATGCTGGTGGAGAGAATACGGAGTGTT
+CAATAGATCCGTAATTGATTTAACTTTAAAATTTGGTTTTTTCATTGTAA
+TAATCATGCTAATCGTCTTGACATGATCTGTTAAATTCTCTCGTTTCGGC
+GGAGAATATAATCGATATTCCAGTGGCACGAGGTTGTCGAGAAATCTATT
+GAAATTCTGATAAATATCGTTCCAATCACTTCGAAGCTCGTCAGTTTCGG
+CTCCAGCTCCGCTTTTGAAGCCAGTCGTTTTTAGATTGTGCTCCAGCGTG
+TCTATTGAGCTCTGAAAATTTGATTTCAAAAATTTTGAGTAACTCAGACA
+ACCCCATTTTTCATCTAATTCGAAATTAGCCACATCTTATAAGAAATTAA
+CCACATCTAATTAGAAAAAACTTTTCTAATTAGAAAGGATGCATATCTAA
+TTAGAAAAGCTGCACACCACATCTAATTAGAAGGGATGCTCGTCGAATTA
+GAAATGAGGCACATCGAATTAGAAAGGGGGCGCGTTGAATTAGAAGTTAT
+GCGCATCTAATTAGAAAGGAGGCACATATAATTAGAAACACATTGCGCAC
+CACATCTAATTAGAAGGGATGCTCGTCGAATAGTACTACCTTTTAATGTA
+TGTACTACCTTTTAATGTATGTACTACCTTTTAATGTATGTACTACCTTT
+TAATGTAAGTACTACCTTTTAATGTATGTACTACCTTTTAATGTATGTAC
+TACCTTTTAATGTATGTACTACCTTTTAATGTATGTACTACCTTTTAATG
+TATTACCTTTTGGCTCTTAATGTTGAAAATAAATCGAATCAAATTAGAAA
+CAATGCGCGTCGAATTAGAAAAAAAGCATGCCGAACTGGTGCGCGTTAGT
+TGACCCTATTTTTCTAATTAGATGAGAGGAATAGGGTTGTCTGAGTAAGA
+CTGCAAATTATCAAAATTTTTTGGTTCAATTTGTTTTTGGAGAAAAAAGT
+GAAATTTCCTGGCAATTTTCAGTATTACGTAGACGTCGAAATATGAGATT
+TTTCACCATTTCTTATGGGTCTCGCCACGCCGACAATCAATTATTGTAGT
+TCATGTCGATTTACGGCGCCACTGTTGCATTAATATTCCAAATGACAAAT
+TTGCCGCCGAGTTTAAAAAATTCAATAAAAGCCCGTAAATCGACATGAAC
+TACAGTAGTTGGTTGTCGGCGTGACGAGACCCAATTCTCATCTTTCGACG
+TCCACGTAATATAGAAATTTTTTTTTTGAAAAAATCAAACGATTTTGCCT
+CAAAAAATTCAAAACTGTAAATTCAAAAAATACCACAAAAAAAAAGCGAA
+AAAAATCGCGGAAGACAGTGGCGCCAGGCTGTCTCAATACAGTTTGATCT
+ACAAAAAATGCGGGAATTTTTTCACAGAAAAATTGTGACGTCAGCACGTT
+CTTAATCATACGAAATCAGATGAGATTTCTGCGTCTGCCATCCCGCATTT
+TTCCAAGATCAAAGTGGAACTGGGACTTTCTGAATAGGACTTTCTGATTC
+CACGTGGGAAGGATGACAAATCCAAAATTGCGATATTTCACTAATTTCAC
+TGCTTGAATTTCCTTGGAACCAATCAGCGTCTTCAAACTCCGCCCACTCC
+ATCTGATTGGTTGAAAAATGGGCGGAGCAAATCGCTGATTGGTCGCAGTT
+CTCATTTTTAGCCAAAGTTAAAAATCTCGATTTTTCAAGGTTTTTTGACC
+ACCTCCAATTCCAAGCTTCTTCCTTACCTTCAAATCGTAGAATATTGCCA
+ATTCTCTGATTGCATCGAGTCCTTCCTTCAAAACCACAACATCTTGCAAC
+TCGAACCCCGAAAGCTGATATTTCTCGTTTAACTTGAATTCTCCTAGAAT
+ATCCTTCGCACGTAGCAACTCTCCAACGATTCCTTCAGTTGGTAGAAACT
+CTTGTAGAGTGTACACTGCCTCCCAGATCTTCTCAAGATCCCCGTAATTC
+CAGACATCTTCCGAGCTAGCCACAAGAAATTGCATATGTTGGTGTTTTTC
+GTTTCGAGCAACACATTCCAATGAGGATACGAAGTTAGACTCGTTGATTT
+TTGTTAAAACGTTTATCATGCTGGCGTAGATTTCCTCGAATTTGGTTTTT
+CTTTCTTGAAATTTTTTGTATAGTTTTGAGGGTACCATACAAAAATTCTC
+GGGAAACTTTTCGATATCATCTATCATCATCGTCAGGTTATCGAAATCTA
+TATACTACAGTGTTTTTTGAAGAGTTTCCACGATATTTTGATCGGTTTGA
+TGTTTGAATGCTTCGAGAATACGCTCGTCTCCGCAACGTCTTAACGTAAT
+GCAAGGCTGTGCGGTGTGTACAAGTGTCTTGTTTAGCTCTTCAAAACCGG
+AGCGATACATAGAAATGGTTTCATGCGCAGCGTCCAGCTGCTCAGGGCTC
+TTGAAAGTTTTCAAACATTCCGAGAAGCTCTCAACAATGCTGTTGAGGTT
+ATCCTTTGGCAGATTTTCCCGAATTTGATTAACTTCTGATAGATATTTAT
+CGATATATTCGATATTTTTATGATATTTTTCCGTGTTGTTTAGGATTTTT
+TGCATCGCAAATTCGAATTCCACATAGTATTCCAAAAACTTATTCAATGG
+ATGCAGGAATTGAATTGATCCTTTGCCAGAAACGCTTTTTATCCAATAAT
+TGCTCTGCTCTTTTATGGACTCTCGAATACTTTCTTCTCGTTTAGGGAGA
+CCTAAAGCTCCACGATCAATTCGTTTTTTGAAAGAAATAATTCAAAAATA
+CCCAAAAGAAAATTGCCTGATGGCCTGGAAGAATGCGTATCCGAGGATTG
+AATACTACGAATAACGTCCCTGACCTTTCGCACCCAATTTGAAAGCCCCA
+GTGTCGTATTGGTGTCGCGAATCATTTCTAAATCACTCAACGCCGCTTCG
+AAATTGTTCAGTCTTCCCACTGACAAGAAGTCTCGAACACTTTTACTTTC
+ATTTTTCATTATAGTCGTAGCGAGTTTGAAGAGATAAAATGGATCTTGAT
+GGAGCAATGCGAATTCTTTCTTGGCTCGTTCCGGAAAGAAATTTCTGTAG
+TAGGCGCCAACCTCTTCGACCGTTTCATAGTTCCGTTCTGTACGATCTTA
+AAAGGTGGAGTACCGAAATCTGGGGAATATTTCTAAATAACTCCAAATTT
+GCTCCTGATTTCAATTATCCATGTGAAAAAATTCAAAAAATCCCTGATTT
+TGTATTTCGGCTTGAAATTGCCGAATTCCATTTGTGCACACATGCAAATT
+TTTCAAACGCGCGCCCAAAGAAATTATCATTGGAGCGCGTTTGCCTCATT
+TGATTCTCTCCGGAGCACGGTAGCACAGAAACTAGATGGATTGGTTCATG
+ATACTCAGTCTGGAAACCTATATTGGCTACTATCTCGAAAACCATCATAA
+AATCGATTTTGCGATGCAAATAAGAAATGACCGCAATGAAATTATCTATC
+TCCATTCGTGATGAATTTTCGATTTTGTACTTCCTGGCCAAGTTATGCAC
+GTTTGTTCGGTGGAGCGCGTTTTCACCCATCTAGCAACTGACACGGTGGT
+TCAGTAGCCAATATAGGTTTCCAGACTGAGTATCATGAACCAATCCATCT
+AGTTTCTGTGCTACCGTGCTGAACCACCGTGCTCCATCTACCGTATTTCT
+TCCATTAATATGGCTGCAATACTATTTTTCGATGGTCTTCCCGCTTGCAA
+TACTAATAGGGAGTGCAATACTAATTTTCAGAATATTTTTCTGCCTTTGA
+GCTTACTAGTTTTTTTCTGAAAAAGCTCGAATTTTATGTAAAAATTCAGA
+AAATTGGTTTTAATTGTAACCTATAAGTTTCAAAAATTCAATCTCGTAGA
+AATTTTTTTGAAAAATTGTTGCAAAATAGGCAAAAAATATTGTAGAAGTC
+CTGAAATTAGCGAGACGGGATTGCAATAAAAAAAAGTAAACGCAAGACTA
+TTAGGGAGTGCAAGACTAATAGGGAGTGCCATACTAATTTTCGGAAGGTC
+TCCGAGGGGCAATACTAATAGGGAGTGCAAATCTAATAGGGAGGCCATAC
+TAATAGAAGAAATACGGTATTTTTAGTTCCTTTATTTTTTCAACGAGAAA
+ATCAAATGAGGCAAACGCGCTGCAATGAAAATTTAAATTTATTTGTGCGC
+GCATTTGAAAAAACTCATTCGGACGCAAATAATATTCACGAATTTAAGCT
+GAAATATAATATCAGGGAAATTTTTTTGTTTTTTTTTCATACAGATATTC
+TGAATCAGAGGAATTTTTTTTAGTTATTTGAAAATATTTCCTAGATTTCG
+GAAATCAAAACAGCAGCTTTTGTACAACAGCTTTTTTTTAAATGTAAAAC
+TTGTTTAAAAGTCAAACCACGTCCATTTTAAAAATTAATTTTTTAACTTA
+TAAAATAAAAACATGTGGAATGCTTTTGCATGTACATTTATACAAGTTTT
+TTGAGAAAAATACATTTAAATTTGAAAAATGTGTTTACTAAAATTCTGAT
+CAATTTTTTTGTTATTATATATTAATAGCTGAACTTTACTTTAAGACAAA
+AATTCCTCTAATTAAAATCTACCTTCAAACCATTTTTTCAGTTTTTGCAA
+ATTCTCCTCGGAAATCGCAGTAGGACTGGGAGCTAGATCATTGAGTGGCG
+AGAGAAAATCACGGAAATTTTTCAGGCGATTTTTCAGGCCCCATGTTGCC
+TCCCATCCGTATTTTGGTTTCATGAGAGATTGGAGATCATGAAATAAATG
+CAAAAAAGCATCCAGCGAGGTGGTGATCTTTTTCAGTGATTCTCGCTGTA
+GTTGAAGATGTGGGAGCTTCTTAAGTAAATTTACAGCTTCTTCTCTATCC
+TTATAAACTTTAGTGTTCTTCCTTTTCCCGACAATCTCCTCGAAAGCTCT
+CTGCTCATCCCATCCGCCAATAGATTTTGTTTTGTAGAAACTTGAAATCC
+TATCAAAATCGATATCCCGATCTAATAGCTGATTCGTCAGATCCGTAGAA
+GCGATTTCGCCGCTGAGAAGCCCATCGACGATAAGATAGCAGTTAAGGAG
+CGGTGGTAGTGAGCTCATCCAGTGAATCCACAGGTTTATGGAGTCCTTTC
+CGTAGACTGAAATTATTTTTAATATTAAAGTAGAAAAAAATTATTATATA
+AACTAACTATACGCAGGAAAACTCGCATTAAGTTCCAGATTTCGATCGAA
+GAATTGTGGATGTCCAGCTGGAAATTTTTATTTAAATTTAGTAAATTTAG
+TGAAGAAATTTAATTTAAAAATACCTGTCAAGCGCTGACCCTTAATCTGC
+TCCAACATTTGAATACCTTGCCGCTCCCTTTCCGAAATTTCGAGATCTCC
+GCAGTGTTTACCCGGTAGAAAAACAAGAAGAAAGGGAATTATCGTTATAA
+TCATCGTTATCTGGAAAAAAATTAATTTTCATGGAATATATTTCAAATTT
+TCGACAACCAAACGCTGAAAATTCACATTTTTTTCAGGAAATTTGGTTGA
+AAAATCTGTTTTTCATAATATTTTGAGAAAAAAACAAGCGTAAAGGTATT
+CAAGGCGCATGCAATTCACTTAAGCCAGGGTCTCGAAGCGAACAGAAAAC
+ATACGGTATTTGAAAATATTCTTGTTTTCCGCGGAAAGTCGCAGAATTTA
+ATTTGATTTTTTTAACTTAAAAAAACAGAAAATTAACCGTTATACCTTTT
+GAGCAAAAAATTCTACAAGATAATAATTTAAAACAATTAAAAATTGAATA
+AACATTGAAAATTAAATGCTTAAATTTCAAGGCGCGTGCATCAAACTTTT
+GTTTGGGTCTCACACCGAATGTAACAAGTACGGTAAGAGTGCGCGCTTAT
+TTTCATTTTTCGAATTTGTGCGACCAGTTCTCATGTTTTTTAAACGATTT
+TTGCGGTAATTTTGGCCATTTTTTCTAGTTCCCACCGACAAATTGCATTA
+TTTCCGTATTTTCAACGAAAATTTTGTTAAAAAACCAACAAAAATTTAGA
+AAATTGCATCATTTTGCAGGGATGAATGGTCAAGCGGATCGCTGCGACCG
+AACCGCCTACGTTTCGGGTCTTCAGCCGACAATCTCCGACATAGAACTGT
+TCGAGGTGTTCAATCGTGTCGCTCACGTCGAGAAGGTCATCGTTCGCAAT
+GGAGCCGCCCGTCACGCGCTCATTGTTTTCAAGTTGGCATTTTTTTTCCA
+TTTTTCCTCATCTAAATCTCTAATTTTCCTATTTTCAGAACTGTTCAAGG
+CCTGTATCAGGTGCTCGTAAACTTTCAAGGAACAACTCTTCACGGCCGTC
+AGCTGCACATTCGTCCACTGCGAGAAAGTTCGCACGCGAACAGCGAGGCC
+ATCTCAACGATGTTCGAGAAGGTCAAACATCAGGGAAATTCCGGGAATTC
+TTCGTATCGTCAAGAGCACTCGTTCCCCGAGTACCGAAACCAGAACCCAC
+AGGCTTCATCATACCTTCCACCGAATCCACGTGGTCATCGAAACTCGACG
+GGCTGTTTCAATGGTGGCGGCGGGGGCTATGGACGCCGACGTTCCGCCGG
+TGGATACAATCAGTACAATCAGAACAAGTATCCGAACGAAACGTACCCGG
+GAATGACTCTGTTCGATAATCATCCAGTGCAGCAGTATTCGGGCTTCAAT
+CCCATCGATTTTCGCTTTGATGACTATGTGGAAGGAGCCAAAAGGTGCAA
+AATTCGCCAAATTTCGCTAAAAAATCTGAAATTTCGCCGACTTTTCCCGT
+AGCGCAGCAGTTTTTTCTTGATTTAGGCACATTTCAGGCAATTATTTTCG
+GCAAATCAATATTTTTCCACCATATATGTTCTAGAATGTTTTAGATGTAC
+TAGATTTTATTTTCAGACGAATCAAGTGATTTTCTATATTTTTACACTAT
+TTTTTGTTGAAATATGACCAGAATATGCAACAAAGTGTTCCAGCTGCTGC
+GAAAAGGAAAAATCGGCGAAATTTCGAATTTCAGTCTATTTTAATCTGTT
+TAAGCAAAAAGAAAACTAATTTTTAAAATTCAGATTCGACAACCTTGCCA
+ACCTGATTCGCTCGAGCACCCCCACGGATCCGTTCGCTAATTATCAAAAG
+TATTTTTGAATTATTTTGAAAATCAATAAATTGGTTTTTTTTTCAGACCT
+TGTGAATCCACAAGCACATCTCGTTCTCGTACGAATTCAGCAAAAGATCA
+AAAGCATGGCCCGCCAACGTGGAAAATGGAGCTGCAGATTAAGAAAGATG
+ACCACCACCACGCCGGCGGCGGAGCAGCAACCACAGGACAGAAGCTGTCC
+CCACAACAGTTTTTGGCTCAGATAGCTCAGAGACAACAATCGGAGCAAAA
+CGCGGATGAGGTGGCCAAGAAGAAGCGTCCGAACCTTTCGGTTATCAATC
+CATCGCTTTTCTATGAGCAATACCCGAGAACATCGTCGCCAGTTGTTTAT
+GCTTCAAAATCTAGTAATATTTTTTGGAGATTTTGGGAAAAAAACAAATT
+TTCTCGAAAATACGCCCGAAATAGTGTTTCACGCGAAAATTGGCGATATT
+TCAATTTTTCTGAAAAATTGCTATAATTTTTTCGATTTTCACGTGAAATT
+GCAAGTTTTTGGATATTTTTCTCGAAAAACGTCAATTCATCGATTTACGC
+AGCTAGTATACTCAGCAATTGACCATTTTTTTGCAGACAATTTGGTATTT
+TTTACTTAAAATTCTTGATTTTCGACTTCTCGTGTGCTAATCACTTTTTC
+AAATGCGCGCCCGAAGAATTTCTCATTGGAGCGTGCTTGCTTCGTGTAGA
+TTTACGAGAGCTTTCCATTTATTTAACTTCTTTCGTGCTTTTTCAGTTTT
+CCAGCGAGTTTCTGGCTCGACCCCTCGGTGTATTTTGTGCAAACACCGTC
+ACGCGCAAATGCATGCACTTTTTCAACGCGCTGCGTGAAAATTCCTCTTG
+CGATTTCAAATATTTTTTCCCGCCATTTTCCAAAATTTTCGAGAGGGGGG
+GGGTCGAGCCAGAACACCTTGGTTTTCCAGCGAGCTTCCTTCATTTACGT
+CGATTTTTTTTTTAATCTTCGTTAAAGTTCTAAAAAAAAACGACTTAAAT
+CATTTTAAATTTTCCAAAATTCGGTTTTCCTTCTGCAAAAAAAATCAATT
+TCCAGAACCATCCGGCCACTACGACGACAAAATCGCATCTCCACACGATC
+CGGCAGTTCTCGCTTACAGTCGCCTTCGTGTACCTCAATCGGCCTTCGAC
+AGTCTCTCACCAATCGACACCGACAATTGCTCATTCATCACAAAACACTT
+GGGACCAACAACCGGTGTGAAGCGTGATTTGACGAACGACGAGTTGTCGG
+ATATGATTGTATCAACTGGAAATCTCCGAATCAATCCAACCAACATCGAT
+CATCATGACGAACCGGCACCATGGTCTCCGCTGAAACGTCTTCGCGCCGA
+AAGTGGATCCCTATCAACTGCACAAGTCGCGTCGCCCGAGTTCTCACCGA
+TCAAACCAAAGACAATGGAGTTCCACGAGACTGAGGATGATGTTTTTGAA
+ACTGGACCACCACCAACCTACTTATCCGAAGGAAACGAAAACGCGGAGAA
+GAAATGTGTTGAGCAGCCGAAAATCAACTACGACGACATTAATAATAGTC
+GTCTTCCGTCGAATTCTCATTCGGCAGCACCGAATTCCGAGAAGAAGCAT
+TTCGTTTTTCCGGTACGGGGGCTTTTTTTTGAATTACCGAAAAAATTCCC
+AACTTTTTAAAGTTCAAAAAAGTCAAAATTTTTGTCCATTTTCTGGGCGT
+GACTGCTTATGCCCCGCCCCCCTTTTTCGAAGTTTCTGCTTCTCGGAAAA
+TGTATTCCCAAAGTGCCAGTTTTGAGGCCCCACGAAAAGGGAGCAGAACG
+AAAGAGGCACCACGGATTCAAGATCTGGTGCGATTCCGGATCTGGCACCG
+TGCCAACAACTTGAAAACGTGGTGCCTCTGAAAATTTGCTGCCAAGGTTG
+AAATATCGAATGCATTACCCGTAAATCGACACGAGCTACAGTAACCTGTT
+ATCCGCGTGGCGAGACCCATGCGCGTCAGATGTGGCGAAAATTATACTAA
+AACCTGTTTAACTTGCAGAAAAACTTAATTTTTTTTGTTGAAAAAATTGA
+GCCAAAAGACTCAAAAATTTCATAAAGCGAAACTTTAAAAAAATATATAA
+TTTGTTAAAAATTTCACGAAATATTTATGAATTAATTAATTTTTCCAGGA
+ATACCCAATGTGCCGTCACTCGTCAGTTCCATCGATTGCTCACTTGGTCG
+GTGATCTGTCGGACTTTTGCCCACACGCTACAGCCGACGAGAAGATGCTG
+CTCGACGAGGCGTCTTCAATCATCGAAAATACAACTCCAGCAGTGTCTAC
+TGCTCCGGCTGCTGCTCCAGGAGCTACAATGCTCCAAATATAGGAGAAGA
+TCACATATACAATAATATAATCTTATTGCATTTTCGCAATTCTCGTTCTC
+TCCACACACATACACACATCATCCCAAGTATTCCTGTGCTGAATCTCAGT
+TTGAATGATGTTTCATACCGTTTTTATCCCACTATTGCCTTATCGTTTCC
+TGTTTTATTATATTTTTCATTTTTTATATTGCCACCACCACCACCAACAC
+CACCCTCTCTATCTTTTTTTGTTCTTTTGCCTCCAGCAACATCATCACCT
+AGTTTTCTGTGAATTTTGAATTTTGTGTTCCCCCGAGTCCCCTCTGATAG
+GAATGATAGGAAAAACAATGAAAATGCGAGTTTTTTCAAAAAAAAAAATA
+CAAACTAGGAAACTATAGAAACAAAAAAAAAACATTTGAGGCGCAGTACC
+GAAATCTCTCCAAATTTGGCCCGAAAAATTCAAAAGAAAATATTTATTTT
+TCTAAATTATTATTTTTCCGCCACTCCAGCCTCATTCTCATTGGAGCGCG
+CAAAGTCATGTCGATTTACGAGATTAAGATTTTCAACGAGTTTCATCATT
+GTTATCGATTTTCGTGTAAAGTTAACTAATTTTTTTGAAAATTTTCGCAA
+AAAATTTTGGATAATAAAATGTTCAATTGGCACGAAAATGCAGATCTTCA
+GCAAAAAAACCGACAGAAATGTGTAAAACTGAATCTCGTAAATCCACATG
+GCATAACGCGCTCCAATGAGAATGTTTTTAGCGAAAAGTTTGAACAAAGG
+AATATCAAATCAGGGCCAAATTTGGAGCAATTTCTAAAATATTTTCTCAA
+TTCTTTCGGTATTCCACATTCAAACAATTATTCGGCCGTTCCCATGAGCC
+TCTGAATCTCGATGGGATCCCTTGGCACTGCAGCAGTCAACAGCTCAATC
+CCTCCAGCTTCACTAGTCGCCACGTCATCCTCGATACGGTATCCAATGCC
+ACGAAACTCTTTGACAGGCCAATCCATCGGAACATACACTCCCGGCTCAA
+TGGTAAATGGCACATTCGGTGGTAGATCAATGTCTCGGGATACTGTCGGA
+CAATCGTGAACATCCATTCCGAGATAATGACTGACGTGGTGGGGACACAG
+CTTCTCCGCCTGATGAATCATCTCCTTGTGATCCGTAGATCGAATCAGGC
+CGAGTTCGGTGAAACTTGCCGCGAGAAGTTCGTTCATTCGGCGGAACAGG
+GCGCTTAGGCGGACTTTTTCCATTGAGTGGGCGTAGGTGAGCAGTTCTTC
+GTGAACGTAGAGAAGCGCTTCGTAGAGGGATAGTTGGGCGTCTGACCAGC
+TGCAAAAACGAATTTTTTTTTGGGAAGGTTTTTTGAAACGATTTTTCAAA
+TTTCGTTCGAATTATATTAAACTTTATATAAAACGATTATCCACGGATTT
+CTGGCTTCCCTCATAAATTGGAATGGAAGAGTTTACCGAACTAGGCCATT
+TTGGCTCGGCCATATCTGGTGCCGCGTCGCGGCTCGATTTTAGTTGTAAA
+ACTAAATGCATTTGTACGTGTGGAGTACACGACTTTCCCACGCGTTGTCC
+GGCGGGCGATTGTCAATGGAGCGCAAAAAATTCACTGAGGAAGGGGAGAA
+CTCCGTGATTAGCACCGCCTATTTCTCTCACGAATCTATTTCTTCGAAAT
+CTTCTATTTTTTAAAAATCAATTCCTGAATTCTGAAATTCATTATAGCGT
+AATTTTTTGGGAATTTCACCCTGAATTCCATTTCTACGGAACAACATTTT
+TTTCTCGAATTTGTGGTGACTCAAATTAGAATTTTCAAAATCTCCAGAAA
+AAAAATCATTTTTCCTGAATTTTCTGGAGATTTTTAAAGGAATAAAGTGC
+AAAAAAGACTCTTTTTGAGGCACCACCGAAAGGAGAAAGGAGAACACAAA
+CCACGCCCATTTTTCCGTGCCGCGCGCAAGTTTTTCTGCAAATTTTTATT
+TTCAAACGAGACAGCGAAACTCCGAAATAACGCATATCGTGTTCTTTATC
+ATCAACGTGTTATTTCGGAGCTTCGTTGTCTCGTTTGAAAATAAAAATTT
+GCAGAAAAACTTGCGCGCGGCACGGAAAAAATGGGCGTGGTTTCTGTTCT
+CCTTTTTCACCTGTTCTCCTTTCGGTGGTGCCTCTTCTTTTTTTTTTCTA
+TGTTTAGCGTAATTTTTTAGCCATCTTGGAATAGCCCCGCCCATTTCTCC
+CACAAATCCATATCTACGAAATCTCGCATTCCAGAATGATTTGTGGTGTC
+TCAAACGGGAATATTCAAAATTTCTAGAAAAACCCCATTTTTCTTGAATT
+TTGGCCGAACTTCTGTAATTTCTGAAATTCTGAGAAAAATTTTCATTTGA
+GTCACCACAAATACTGGAATGCAAGATTTCGTAGAAATAGACTTGTGGGC
+GAAATCAGCAAAAAATGGGAAAACATTCAATTTTTTTTAATTTTTTGGGG
+TTTTATCACTAATTTTTAGCACTTACAATCCAGAAATCGGAAAGCAACGT
+GTCACATCTGACACATAACCATTCAAATCACACCCAGCATCCACGAGAAC
+ACATTCCCGGGGATTTAGGTCATTATTTGCGTCCAAATAGTGAATAGTGT
+TGGCACGAACACCACCGGCAATCACTGGTGGATATGCTTGCATTTCTGAT
+CCACGACGACGTCCTTCAAACTCCAAGAGCCCGCAAATCGCGTTCTCGTT
+GTGTAGATCACGTGATCCCGATATCATTGAGCTCATTGTCTGGGCTCCCA
+CGTTGCACACGTCACGCATTGAGCTCATTTCGGATGGAGATTTTATTACT
+CGGCGACGTTCGATCTGCAAGGAAAACTTGAAAATTGGCAAAAAAATAAT
+TTTTTTTTTGAAATTTTAAAACGATTTTTCGGGTGTTCAGAAAAATTTTT
+TTTAGGAAAAAATTGGAATTTTCCAAAAGTTTCAAAAAAATAATTTCTAG
+AACTTTTTCCTAAAAAAAAAATGAATATTGAAAGCTTCGAAAACAGTAAA
+AATTGGGAAAATTTTTTTACCGTTAAAAAATTTTTTTTTTTCGAAAAAAA
+AATTTTCAGTTTAAAATTTGGAGCGTTTTCAATTTTATTGATAATTGGTG
+AAACAAAATAAAAAGTAAATAAAAAATTTTTTTTTTGAAAAATTTGAAAA
+ATTAGATTAAAAATGTTTATTCTGGGATGAAAAAAACCTCCTAAAACCAT
+TTTCTGGAAAATTTAAACTTCCTATTTTGTTCAGACAATTCTTTTTTTTC
+AAGAAAAAATCAAATTTTCCACTAGAAAATCGAAAAAAATTGACCTCGTT
+TAAAAATTGGACAAAATTTGAATTTTTACTTTGAAATCCTCGAAAATCGG
+ATTTTTTTTTCAAAGCTTGAACAATTTTCTGCAAATTCTATATATCTCTA
+AACTCACAAAATGATTAATTTCCCGAACAGAATTAGCTTTAGCCTGTACA
+AACTTATAGAGTAAATCATCAGAAGTCGAATCAAAAAACACTGCAGTTCC
+CTTATCGCAAACTTTTTCCAAAGTCTGTAGAATCCGGCTAGTCGGCACAC
+ATTCCGTGAATTTTGCAGTCTTTTCCCATTCGGATTCAGTTGGTAGGGCG
+CCTTCCCATAGCTCATCATAGGCACTACGACGGTCAGCAAAAAGAATATT
+TGTTTCTTTTGAAGATTCGGATATTCCTGATTGCATTATGTAATAACAAT
+CTGGTGTGGTGATTCCGTTTAGGTATCTGCAAAAAAAAAAAATTTTTCAA
+ATTTTTTTCTGTTAAAAATTTAATTTATTTTTTTTATCAAACAATTTTGA
+ATTTTTCCCAAAAAAAATCCGAAAATTGTGAACAAATCTATTATTTTCGT
+TGAACAAAAAAAAAACAAATTCAATTTTTAAATAATTTAATTTTCGTTCA
+GAAAAAGAAATTTGTCGATTTTCGGCGGCAATGATTTTTTTTAACGAAAT
+TTTCCTGAAAAATTCAATATTTCAATAATTCCTGATTTTCTAGTTTTTTT
+TTTAAAGAAGAACATGTTAAATTTCTACTAATTTTATAACAAAAAATTTC
+GGGAAAATCTAGAATTAAAAAAAAATGTTTTCAGAAAAATTCTACTAATA
+TATTAATTTTAGCTTAAATTTCGATAATTTTAGGTTATTTTTCAATTTTT
+TTAGGGCGAAATTTTGATTTTCAAAACAAAAATATTTTCTGACAAAAAAA
+TTAATTTTCATTCTTTTTTAGATTTTTTGAAAAATTTTCAATTTTTTTCT
+GAAGAATTTGGTACTTGTGTATTACATGCCCTCATTTTTAAATTAAATTA
+AATGTTCATTAATTTCTCCATTTAAATTAAACGTGATATACATTTTCTCT
+TTTTAGGCTTAGAAATTGCTATTTTGCTACTTAAAAAATTACTATTAAAA
+TGAGGGCATGTAATACACAAGTACCAAGAATTTCAATCAATTCTTGTTTT
+TGAAATTTTTTTTGGGAAAAATTCCAATTTTCGATTGTTTCTTCGATTTT
+TTCAGAAAAAAAATTTTCTAAAATTTATTTATTTGTTTGAAAATTGGATC
+TAAAAAAATTTCTCTAGTTTTTATTTTTTTTCTGGAAAAAGCTTTTTTTA
+ACTTAAAAAGTTAATCTGTGGCCGAGTTTTCTCTCATCATTTTCACGGCC
+ACGGCCATCAAAACCGAACCTGAAATGGCTTTTCTGTCGGAACGCGTGTG
+GAACATCCGGTGCAATATATGATTTCCGTGCTCCTTTCATCACAACGACC
+ACTTGCTTTTCTGAAACTTTGAGAGGTCATGGCCTAACTTTTAAATGGTT
+TTCTAGGCCACCATGGTGATTTTATTACGGTACCGGGTCTCGACACGATG
+AATTTTGTAGAATAAATTTTTCTGAAAAATTTCGTTTTTTTTTTTAGAAA
+AATCAAATTTTCAAGAAAAATGGGAAAACATTTTTCAGGAAAAATTTAAT
+TTTATAGAGAAAAATAGAATTTTTCCTTTAAAAAAATCTGAAAATTCGGA
+TTTTTGAGAATTCTCTTTATTTGGATTTTAAAATCCAAATTTTCAAAAAA
+AAATTTAAAAATCGGAAAATTCCAAATTTTTGAGAGTAAACTCGCCTTAA
+TTTTTTTTTTCAATTAAAAAAATTAATTTTTTAAAAGAAAATTGGAATTT
+TTACCCAAAAATTGGCAATTATTCGAGTTTTCAACGGAAAAATCTGAAAA
+ATCCGAATTTTTGAAAAAAAAATCTTTAAAAATCCCAATATTCAATTAAA
+AACCGCGAAATTTCGGATTTTTGAGAAAATTTTAATTTAAAAAAGTCCTA
+TTTGTACTGCAAATCCTCATTTCCAAATGATGGCCTAACTTTTTCAGAAT
+TCTAGGCCACCAGGCCATTTCTCTGCCTCTTACCCCCAGTTTTGACCTCT
+TTTTTGAGTAAATTCATCAAATTCGTCCTTCTCATCGCATATTCCTCATT
+TGGAATTCGCGATGGCCACATTGGTAGGCTCCGCCCACTTCTGAGCATTT
+TTTTTTTGGATCTGATCTGTGTGGGAGGGAAATTCGAATTTTTTTAGAAA
+TGAATAAAACTGAAAAAAATAGATTTTTTGGGAAACAGGGAACCTGAATT
+TTCGAGAGAAAAAAGGAGGTAAAACAAAAAATTCGATTTTATATTGAGCA
+AAAATTAATAGAAAAAATAAACTTAACAATTATGAACAGAAAAACCTACT
+AAAAAAGTCTAAAAAATGAATGAAAAATTGCAAAAAAAATCTACAATCGA
+TACGAGACTCCTCCTCCAACAATGCAGTTCTCGCCGGTGATGTACCTGAA
+AAAAAGTGATTTTTTTTTGAATTTTTAGAAAACAAAATTATGAAAAAAAC
+CAAAAAATTTCCGAATAATCGAAATTTTTCGGAAGTTTTAGGTTAAAAAA
+ATTTTTTTTTGATGAAAAGTTTTTTTTCAACAATTCTGAAAACTAAAAGT
+ACCAAAAAATTTTAGTTTTTTCGATTGTTTCAATATGATAATTTTTTTTA
+AATGTTTAAAATTGTATTTTTTCAAAAAATATTATCAATTTTCCAATTTT
+ATGGTAATTTTGGATGTGAGATTTTTTTCTTCAAATTTTCGAAACGTTTC
+TCGATAAAAAAATTTTTCAACTGAAAAACTACAAAAAATCCTCTTATTTT
+GAAGAAAAATCGATATTTTCTCAAATTGTTCAGATTTTTTCTGTTTTTAC
+CAAAAGTGACCAAATTTTGAGACTTTTCGATCCAATGTTTAAAATTTTTT
+TCCCGTTTTTTCGATATTTGCGGTTTAAATTTTTTTTAAATTTTTTGATT
+CAATTTTAATAAGTTTGAGTGTTTTTCGATTTTTTGTCCAAATTTTTTCA
+AATTTTTTTCCAGAAAATTGGTAGAAGCCAAAAAGTGCGATTTTTTTCCT
+TAAAAAAGATAATTATTCAGTTTTTCGACTGTTTTCTTCTTGCTTCCAGA
+TTTTTTCTCGAATTTTTTTTATATTTGAATTGTATTTTTAAATATTATAC
+TCCTAATCGATAAAAATTAGTTTTTTTTTCAATTTAAATTGGAAAAGAAC
+GTTCTTTTTCGTAAATTTTAGTGATTTTTGATTCCAAATTTTTGGATTTT
+TTCAAAAAATTTCCCAGAAAATTTTACCTGGCTTTGGTAGAAGCCAGAAA
+TTCGATTAAATAAGCTTTTTTGGGTTTTTCGACAATTTGTCAAGTTAGGA
+ATTAAACTTTTAAAATTTTTTTCAAAAATTTTAAAAAACTAAAAGTATTT
+CTGAGAATTTTTCTGAAATTAATTATTCAGTTTTTCGACTGATTTCTGCT
+TGCTTCCAGATTTTTTCTCGAAGTTTTTATATTTGATTTTTTTAAAAAAT
+ACTCTTAATCGAAAAAAATTCATTTTTTGAATTTTTTCGGGACTTTTTTT
+TTCGAAATTTTCGTAAGTGTTAGTGTTTTTCGATTTTTGATTCTAAATTA
+TTGGATTTCTTCAAAAAATTTTTTCAGAAAATTCTACCTGGCTCTGGTAG
+AAGCCAGAAATTCGATTGAAGAAGCTTTTTTTTCGGTTTTTTGGACAATT
+TTCCAAGTTTTAGTTAGGAGTTAAACTTTTTCAAATTTTTTTTGAATTTT
+TTTCAAAAACTTTAAAAACTAAAAGTATTTCTGAGAATTTTTGAGAAAAG
+CATTTTTTTTCTCGAATATTTGAACTTTTTAAATTTTTAAAGCTTTTTAT
+TTTTAAATATCAATTCGAATATTTTACTCTTAATCAATGAAAAATCGATT
+TTTTTGATAATTTTTTTCAAAAAAAAATTCGAATTTGAAATTTTTTTCAT
+TCAGAAAAGGGAATTTGACTATTTGAAAACAATTTTTTGTTGAATTTTTC
+GTAAATTTGAGTGATTTTCGATTTTTGATTCCAAATTTTTGGATTTTTTT
+TTGACAATTTTCCAAGTTTTGGTTAGGAGTTAGATTTCTTGGAATTTTTT
+TTTGAATTTTTTTCAAAAATTTTAAAAACTAAAAGAATTTCTGAGATTTT
+TTCCTTAAAAAAGAGGAATTTTTTAGTTTTTCGACAGATTTCTGCTTGCT
+TCCAGATTTTTTCTCCAAGTTTTTATATTTAAATCTTTAAAATTTATATT
+TTTAAATAATATTTCAGATATTATACTCCTAATCGATAAAAATTCGTTTT
+TTTTTCAAATTTTAATTGAAAAAAATCGATTTTTTCGATAATTTTTTAAT
+TTTTTTAAAATTCGAATTTGAAACTTTTTCATTCAGAAAAGAGAATTTGA
+TTATTTGAAAACAATTTTTAATTTAATTTTTTAATCCTTTAAATTTTCGT
+AAATTTGAGTGTTTTTTGATTTTTGATTCCAAATTTTTGGATTTTTTTCC
+AAATTCTCCAAATTCTTATTTTTGCAGAAAATTCTACCTGGCTTTGGTAG
+AAGCCAAAAATTCGATTTAAGAAGCTTTTTTTTGGTTTTTTTTGACAATT
+TTCCAAGTTTTAGTTAGGAGTTAAACTTTTTTCAATTTTTTTTTTTGACT
+TTAAAAAAAAATTTAAAAACTAAAAGTATTTCTTAGTTTTTTCCTTAAAA
+AAGAGGAATTTTTTAGTTTTTCGACTGACTTCGTTTTTGAATTTTTAAAA
+ATTCAAAAATTGTATTTTTTAAAATTCTAATCGATAAAAATTCGTATTTC
+GATTTTTGATTTCAAATTTTTGGATTTTTTTCAAACATTTTTCCAGAAAT
+TTTTACCTGGCTCTGCTAGAAGCCGAAAAGTGAGATTTTTTTCCAAAAAA
+AGATAATTATTTAGTTTTTTTTCTCGAACGTTTTATTATTTGAACTTTAA
+AATTGTATTTTTAAATAATATTAAAAATTTAAATAATAATATAGAATTTT
+TTTGAAAATTCCTGAATTTTCTGATTAAAAAAACATTTTCTGATGCATTT
+TAGAAACTGAAATTTTTTGAAATCTTTTTGGAATTTTGGAAAATTTCGAA
+TTTGTTGATTATACTCTTAATCGATAAAAATTCGTTTTTTTCCAATTTTA
+TTTGAAAAAAATGATTTTTTCGATAATTTTTTTGATTTATTTTCGGGAAT
+TGACTATTTGAAAACAAAAACTTTAAAAAAAAATCAAACTTTTTTTTTGA
+AATTTTCGTATTTAAATTTGAGTGTTTTTCGATTTTTGATTCTAAATTTT
+TGGATTTTTTCCAAATTCTCCAAATTCTTATTTTCAGAAAATTCTACCTA
+GCTCTGGTAGAAGCCAAACATTCGATTTAAGAATCTTTTTTTTTTTTTGG
+ATTTTTTTTTGACAATTTTCCAAGTTTTGGTTAGGAGTTAGATTTCTTGG
+AATTTTTTTTTGAATTTTTTTCAAAAATTTTAAAAACTAAAAGAATTTCT
+GAGATTTTTTCCTTAAAAAAGAGGAATTTTTTAGTTTTTCGACAGATTTC
+TGCTTGCTTCCAGATTTTTTCTCCAAGTTTTTATATTTAAATCTTTAAAA
+TTTATATTTTTAAATAATATTTCAGATATTATACTCCTAATCGATAAAAA
+TTCGTTTTTTTTTTCAAATTTTAATTGAAAAAAATCGATTTTTTCGATAA
+TTTTTGAATTTTTTTTTTACAAATTCGAATTTGAAATTTTTTTCATTCAG
+AAAAGAGAATTTGATTATTTGAAAACAATTTTTAATTTAATTTTTTAATC
+CTTTAAATTTTCGTAAATTTGAGTGTTTTTTGATTTTTGATTCCAAATTT
+TTGGATTTTTTTCCAAATTCTCCAAATTCTTATTTTGCAGAAAATTCTAC
+CTGGCTTTGGTAGAAGCCAAAAATTCGACATAAGAAGCAACATCAGACGG
+TCTTCCAAGTCTTCCCAACGGAATCATCGATTCCAAGTGTTGTTTAATCT
+GACGAGCTTCTTCTCCAGAAGCATGATCCCATACAGCACCAGTTCCGTCT
+CCTTCAATCATTCCAGACACCACACTATTCACGCGGACTCCTTGTTTCGC
+GGCACTCTGAGCTACGGATTTTGTAAGTGATAGGACACTGCTAGATGCAA
+CTGAGTAGAGACCCATATCGATTGATGGAGTGAAGCCGAAACATGACGTT
+AGGTAGATGATACTGCCGTTTCTGGAAAAAATCGATTTTTTTTGGACGGG
+AAATTTTGCCTGCCTACGTGCCTACCTGCCGGCCTATTTTAGCCTATTTT
+TCATTTTTTTTTTGTTGTTCTATTTTTTTGCCGTTTTTTGGGAATTTCAT
+GATTTCTAGGGTAGGCACGACTTCATGCCTACGTGCCTATCTACCGGCCT
+AACATTTGATATTTTTTTAGAATTCCATGATTTCTAGGTAGGCAGGTAGG
+CACGAATACATGCCTGCCTACCGCCTGTTTTTTTGAAATTTTTTTGTGTG
+AAAAATTAAAATTCATGGGAATGCTTTTTTTTTCAAAATTCAATGATTTT
+TAATGCAGACCGCGCCTATCTGCCTACCGCCTATTTTTGGCATTTTTTGT
+GTGCAAAACAAAATCAAATTAGCTTTTTTCTTTTCGTTTTTCTACGATTT
+TTTCCAAATTTCAAGATTTTTCGGATAGGCACGACTTCCCACCTACTGTG
+CCTACCTACCTACCGCCTATTTTCGGCATTTTTTGTGAGCAAAAAGAGAT
+CAAATTAGCTTTTTCTCCTGTTTTCTACGATTTTTTTGGGTAGGCACGAC
+TCCATGCCTACCGTACCTACCTACCTACCTCCTATTTTCGGCATTTTTTC
+TCGTGCAAAAAATCATATTTATGAAAACACTATTATTTTTGTTTTCTGAA
+TTTTTTTTCCAAATTTTGTGATTTCTAGGGTAGGCACCGACTTCATGCCT
+ACGTGCCTACCTACCTACCGCCTATTCTCGGCATTTTTGTGAGCAAAAAA
+TTAACATTCTTGAAAATCCTTTTTTTGTTTTACTACAATTTTTTCAAGTT
+GCATGATCTCTAGGGTAGGCACGATTTCATGCCTACTTGCCTATCTACCT
+ATTTTTCCCTTTTTTCGTGGTTTAGGTAGGCAGGCATGAGTCAGGCACGA
+AAATCTAGAAACATAATTTTGATTCTATCGGTAAAATAGGCTTTCAAGAC
+AGTTTGAATTTTTCGAATTTCTACCAGCAAAAAATAATATCTGAAATTTT
+CGCGGCGAGACCCAAAAACTGACTGAGATTTGGCGAGCGTCGACATAGCG
+GCTTGCGAAAGACGGAACGGTGTTGTCAGATTGTTGGCGAAAAGCTGAAA
+TTGGTTTTTCGAGGTCAATTTTCCACGTGGAATTCAAATTTCAGCACTCT
+CGAACCTTATCAAAATCCTCGCCGGATGTCTCAATAATCTCGCCGAGCAC
+CTCATTCTGTGGTGGAACTATAATTAAAGTGTCCAGACCGCCGAGCTTCT
+CAGCCACTTTCGTGATCAGCTCCTTCCTGTGCTCGGCATTTGCCACGTCT
+AATGAGAAAGCTGTGACGTCACCTCCAACCTGAATTTATTCCCGAATTTC
+TCTTTGTCAAGTTCTGAAAATCTGCCTAAACCTTTATATTGTCCTCTGCA
+ACCTTTCCCACACTATTCGGACAGTCTGCGGCGGCGGCGACCTTGTAGCC
+GGTGAACGCGAGTCTTCTCACGACGGCTTTACCCAGTGTGGACGTTGCCC
+CGATTACAAGTGCACATGACATTACGCTGAAAGCCCGATGAGGAGGCATA
+TTTATAGATACACCTAGACATCAGGTACATTTATTTGGAAATCCGTAGAA
+AATAAAGAACATGTGAAAATAAAACAGATCATTTTATTATTTAGAGGGGA
+GAGGGAGGGGGAGCAAAGTCGCTGACTGAGAACTTTCGAAAACCGGTTAG
+TTACTCCAGTTGTACGGCTTATTCATGCCATATTTTCCAAGATTTCCACC
+ATTGTGTTGGTATTGAGAATGTTGATTCTGCTGAGCTGCCGGCTTCGATC
+CAGACATCTTGTCGTAACTCTTGCGCTCGTCATCCTGTCCGTAGAGTTGA
+CGACCTCCAGCGCTGCTTCCAACATTGGGCATCATGTTCATGAATGGAGT
+AAACTGGTGTGGAGCAGGTGAGTACTGCTGCATGAACAACGACGACAAGT
+TTGGCTGCTGCATGTAGTTCGTCGCCTGGAACCCTGGTGGTGGTCCAACA
+TTCGACGCCTGCTGTGGCTGCTGATCCCGAGAGCTTTGAGATCCGAACTT
+ATTGAAGTCCATAAGTCCATGAGTCTCTCGTTGTTGACCAGATTGCACTT
+GTTGCGCAGAAGCAGCCTGTGACAGAGGAGCAGTTGGAAGCAAGCTTGTA
+AGATCAACTCCCATTCCGTATTGCATAAGAGCAGCAGTATATTGCTCATC
+TCGAACTCCTGGCATTGGATTGTACATGTTCATGTAGTTGTTCATGTATG
+GTGCATATGGGAGTTGTTGAGTGAACATCATATGTGGATGCTGTTGTGGA
+TGTCCAGTCGGTTGTGATTGAGCTGGTGGAGTTTGTTGCTGCTGCTGCAC
+TGGCTGTTGTGGGGCTTGTTGCTGCTGCTGCTGTGGCTGGTGCTGCTGAG
+CAGATTGCTGTGTTGGAAGTGGTCCAGAATTGTTGAACTTGTTCGGCGCC
+ATCCTGTCCGTTGGTTGATATGAAGCGGACGAAGTGTCATAGGACAATCC
+TCTGTTAGATTGACCATATGACAATGGAGGTGAAGTCGATTTTAAGTTGT
+AATCGCCGTTAGGAATTGACGTCCTTTCTGGCTGAAAAATAATCGAGAAT
+TAGAATAAATCGTCTTTGCAACAAATTTAACTCACCTCAACTTGTTTCGG
+CATAATACGAGAAGAGTTAAATATATTTTCACTGGCATTTGAGATCGAGG
+CAGCGGAGGATTCAGTAGAAGGAAGCTGTGGGCTTGGAGCAGCCTCAACA
+AATCCAAATGAGTAGTCATGAATGTTCGTTGGTGCAGTTGTGCCAACAAA
+TTCCACTCCAGGATCAGGAATAATCTGGACTGGTGCTGCACTTGGAATTG
+GAGATAATCCTAGTCCTGGTGCTTCACTCAATCCTATTCCAAGATCCGTC
+TTCAGTTGAGTGGTCCATGCTTGATTTGGTTCTGGGGTGCTTTGTACATT
+TTCATCGTGATGAGTCGACACATTAGGCGTCTGCTCCTCAGCCAAAACTG
+ATGATTCACTGAAAATTAAATTTTTAATAATCTAAATACAGGGACAGAAC
+AACTTACTTTTGGAAGAAACCATCTTCTTTCTCCGGCTGATGCGAAGTTT
+CTGGCTCGAAAAATACTGGCGCTGCTGCTGGCTCTTCTTTAACTGGTGCA
+ACTGACGGAAGTGGAGGTTGTGGGGAGAGACTCCTCCTTGGCGGAGCTGC
+TGGTTGAGGATTCTGTGCCTGGTGCTTTCGGAGTGCTTCTTTGCGATGGG
+CAGCTGCTGCTACTGCAGCAAATGAGATCGGTGCCGGCGCAGAAGATGTG
+GGAACAGTGGCGGTGACGGATTCCTCTACTGGTGGTTGAACTTCGGTGAC
+TGTGGTATCCACTTTAGTCTGATTCTGAAAAAAAAACACGTTTCGTCATT
+TTCCTTCTTCAAAAAATTCTTACCTCATCAAGATCAGCAGTGAACGCATC
+TGGCTCAAGTGCTGATGATGGAGCAACAGCTCGAGAATATCCACCTCTGG
+CGCCACCTCTTCCACCTCGTCCAACATACGGTTTTTCAAATCCTCCTCGA
+GTCGAGCGTGGTGCTGCTCCTTCCTTATTATCACGGTTATCCCGATTATT
+ATCTCGGCTTTCTCTTGGAGCTCCATTGGATCGCCCGCGGCCTCCTCGAT
+CGACGAAACCGGTGCCTCCACCTGAAAAAAACATATCAATATTTGATCTA
+TTTCAATCAAGCACGAACCTCTGCCTCTTGCTACAAATCCTCTGTTGTTA
+TAACTGCCCTCTTCCGGCTTCTTCTTTTCCTTTTTGGCTCCTTTCTGTTC
+AGTCCACGAGTCAAGTTTATCTCCAGCATCCAGAATGTGATCGATTGCGC
+CGTAAAGATTGTTGTCAGTATCCAATAGCGCTATCTCAGCTTGTGCTTGT
+GTACATCCGGTGGTTTCGATAATCTGAAAATGAAAAAGACATGAGCAGTG
+AAAAAACCCCTCTTGGGAATGCGCGAACACTTTAATTAGCCCAAATGAGT
+AGGACATCTGGGTACTCTTACTCTCGCTGCACCATCTCAAGCGCGGACAC
+CTGCTTTTGTCCTTTTATTTGCCATCTGGCCCCGTCTTATCGATTCGAAA
+TTCCTATTGACACTGAAAGCGGACACTAGAGAAGTTCAAAACAACAAAGT
+CACGTGCGTCATCATGTCGGTGTGTGGCGAGCGTTCGCGTGATGCAAAGA
+TCACTATTTTCAGGAAAGCGTCATTTCCAGCTTGGAGACTTACCGTCTTG
+ATCATAAACTGTATGTCCTCCTCATTTCCGGAATTTCCTTCCAGTGTGAG
+TCGTGCAAGTCGCGCTTGATCGCTGGTAGCTTTTTTGTCGCCTTTAATAC
+CCATTCTGAAAACAAATTATAAATAAAAAGGGTCAGTCATGTGAACGCAA
+GAATGGAATGAGAATCACGAGAATACAACTATCAAAGGAAGGTTGAATGA
+AAGGAAGGTCAAATAGATGACAAAAGTAGGAAAAGAACGAAATATGGAAC
+CTTCCAGATCAAAAAAACATTATCAAAAGAAAAGCCTCGCACAGAAGACT
+CTAACGAACATGTTAGGATGAAGAAATATTTCAGCAATACATCACGTTGA
+ACTTTGGAGGATATTCTAGAGAAGAAAACCCCTACATTTTACAATAATTT
+TGAAATGGAATTCGAATGAACTGCTATACAATGGAGAATCCTATTTAGCG
+ATGATAAAGTGTAGGCTTGTTACTAGATTGAATAAAAATTTCGAAATGTA
+ACAATACATTGACTGAAAATTTGGGTATTTCAGAGTGTGATATCACAAAA
+ATCAATATTTCCACTAAACTCAAAAGTTCTTACGCTGAAAAATCATTAAA
+AAATTGAAAAATCACCGCAAGCTAGACTAGAATCGCGTTCAAATCTCGCA
+AATTCCCGCAGTTGAAAATGCGGGCGACCGCGACGCGAGCCGCAACGCAC
+CCCTCCAAACATGCGGCATGGGTCTCGCCACGACCGAAAGTACGGTCACT
+CTTGGCAGTATAAAAGGCGACCATTTTCCGCTATTTTCCGGTAAATTTTC
+AAATGAAACTGTGTTGCGGAGGGGGTTTTCCGCTAATTTTGCGGAAATTT
+AGCTATTTAATGTGAAAATGTGAATAAAACAAAAGAAAGTGGGGAGGAAT
+AGCAAGGAAACACACTGTTGAACCCTGGGAATTATCGATTTTGTATGAAC
+TCTTCTTTTATGGCGTCGAAATTATCGACACGAAAACTCAAAACCTTGTC
+ACATTTCTGAGAGAGAAATATCATTTTCAGCACACATGAGTCTTCCCAGA
+TTTCGACTCGTTCAGGGAAAGGCGATCGGCGAGCGATCAACGCCAGGAGT
+CAGCACACCAGAGCCGGTAATTGTTTTTTTTTATTTCAAAATTTCTACAA
+CAACAAAAAGAACTAACAATAATTTATTCCTTTGATTCCAGGCCCCTCCG
+CAAATAAAGCAGGAAGTCGACTACCAAGATGCTCATCAAATGGCTCCGGA
+ACCCGTGGAAGCACCCCGTAAATATTTAAAAATTTAAAAAAGTTAGAAAA
+AAAATTTGAATCCCAATTTTCAGAGGCTCAAAACCATCAAATGCAGCCGC
+CTCGTCAACCTATACAACAGCAGATGCAGCATTTTCAGTCACCATCGCCA
+ATGGCTCCACAAGGGCCGCCCGGGACTCCACAAAACTCTGCAGCGGCGGC
+CGCCGCTGCTTCAGATGACAAAAACGTGACAAAATGCGTCCGCTTTCTGA
+AAACTTTAATTAATCTGTCGAATAACGATGATCCAGAAATGCCGGACAAG
+GCCGCCCGTGTCAAAGAGCTAATTCGAGTGAGGAATTGAGCGAAAAACGC
+GATAAAAACCGGACAAATTCGGATATTTCAGGGCGTAATTTATCTGGAAA
+CGACGGCTGAAGAGTTTACACGAAATCTGCAACAAGTGCTCAAATCTCAG
+GCTCAACCGCATCTTTTACCATTCCTTCAGAATACTCTTCCGGCATTGAG
+GAATGCTGTTCGAAATGGTTCGGTTTTATGTGCAAAAAAATTAAAATCGA
+CAAAAAAAAAATCATCGAAAAACAGGAAAATTTGAGTTGAAAAGCAGCGA
+AAAACTTGAATTTAACATAAAAAATTGCAAAAAATCCGTTGAATTACATT
+TTTCAAGAAATTGTGTAGAAATTCCATGAAAAAAATTCAAAATTTCCAAA
+TTTTTTGGCTATTTCTAGTCAATTTCTTTAAAATTCCATTTTTGATAGCG
+AAAATTATCAAGTTTCTAACAATTTCAAGCTGTTTTTGGTGATTTTTTCA
+ATTTTTCGGCTTTGAAATTCCATTTTCCGGAGTATATTGTCATAATATAT
+CCGAGTTCCACAAAATTGAGCAAAAAAAATTAAAAATTTCCCTTTATTTA
+AAAATATTTTCAGCTGTCAGTAATATATGGATTTTCCGCAATTTTTCTCA
+CAATTTTGAGCAAATTCCTGATTTTCAGCCAATTTATAAGGATTTTCACC
+CATTTTCATAATTTAGGGCTATTTTCAGCTGAAAAATTGTAATTTAAAGT
+TTTTAAAATTTTTATAGATTTTCTCAAATTTCAGCTCAAAAATTCGATTT
+TCAAGCGCATTTCCAGGCAATTTATTAAGATTTTCACCAATTTTTTTAGC
+TTAAAATTTAAAATTTCCACATTTTTTGTCTATTTCCAGTAAATTTCTTT
+AAAATTCTATTTTTGAAAGCAAAAATTATCAAGTTTATCGCACTTTTTCA
+ATTTTTCCGGAGTATATTTTGGTAATTTATCCGAGTTCCACGAAATTGAG
+CAAAACAATTATTTAAAAACTTCCCTTTATTTAGAGCTATTTCCGCAAAT
+TTTCTCGCAATTTTCACGCAATTTTCATAATTCAGGGCTATTTTCAGCTG
+AAAAATTGCAATTTAAAGTTTTTAAAATGTTTATAGATTTTCTCAACATT
+CAGCTCAAAAATTCGATTTTGAGGCGCATTTCCAGGCAATTTATGAGGAT
+TTTTACCTATTTTCTAGATTAAAAATCTTTTTTTTTCCTCAATTTTGGAC
+TATTTTCCCTAATTTTCAAATTTCCAGGCACTGCATCAGTTGAAGGCGTA
+AATCCACCGCCTGGCTACGTTTTCAACAATGGAAGAACCCCAGGACCCCC
+TCAGCCACCTCCACCTCAACAACAATCCCAGCAGCAGCCACCACTAGAAA
+TGCGTCAAATTCCGAATCCGAATCAAATACCCCCACAAATGGTTCAAGGG
+GGTCCCCATATGGTATCTGTAGGCGCCCGGCCAATGATCAGGCCTATGGG
+CCCCGGCGGCCCAAGCCCAATGGGCCTACAAGGCCCCGTACGAGGGCCGA
+TGGGACATCAGATGGTCCAGATGCATCCTCCTCCCCCACCACAGCAGATT
+CAACAGCAGCACCCGGCTCCCCCTGTAGAAATGGAGGTGGAAGAGAATTT
+ACAGCCTACCGCGGCGGCCACGGCCACGAGGCAATATCCTGAAGGATCGC
+TGAAATCGTCGATTCTGAAGCCGGATGAGGTGCTGAATAGGATCACGAAA
+CGAATGATGTCATCGTGTTCGGTGGAAGAGGAGGCGCTTGTCGCGATTTC
+AGATGCTGTTGAGTCGCATTTAAGGGAACTTATTACACTGATGGCCGGAG
+TTGCAGAACATCGGGTGGAGAGTTTGAGGTATTGAGGAGAATTGATTTTG
+CTTCAAAATACGGCAGCGAAAAAAAAATTAAGCAAAAATAAGGAAATTAT
+TGAAGAAAAATCGTCTTAAAAACAATTTTACATTAAAAAAAAAGATTTTT
+AAATTTCAAAGGTTCCGAACTATTTATTAAAAAAACATCTAGATTTTGTT
+TTAAAATCCAAACAAAAAACATTGCTGAAACGCGGTAATTTTTTTTCAAA
+AAAATATAAAAATCTGAGAAATATTTTCAAAAATATCTCCAATTTTCCCC
+TGATTCCGAATATCTATTCGAAAAAATTCAAAAAAAAAATTTCCCTTTAT
+ATTTCAGCTTGAAATCGCTTTGTGCATGCACACCATGAGATTTTTCAAAT
+GCGCGCCCAGATAAATTCTCATTGGGGCGCACTTGCTTCGTGTCGATTTA
+CGGGAGCTCTTCATTTTTAAATTTCTTTTAAGCTTTTTTTTTCAGTTTTT
+CAACGAGTTTCCTTGATCTTCGTCGATTTTTTGTCATTTTTTTTCCTGAA
+ATTTTGTTTTGTGTCAATTTGAAAATTTTTTAGGTCAAAACTCCTGTGTT
+CGTCGAGATCTGACGTAAAAATATAAAATTCCGGGAGTTTTGAGATATAA
+AAAAAATATTTTAAAAATTTCAGAAAAAAAACTGACAAAAAAGCGACAAA
+ATAAAAGAAACGCGCAAAAAAAAAAAAAAAAAACTTAAAAAAGCACGAAT
+AAATTTTTTTAAAAAATGGAGAGCTGCCGTAAATCGACACGAAGCAAGCA
+TAAAAAAATGGCTTTTTTCCTAACAATTTTTTGTGAAAAATCCGAATTTT
+CCATCCTAAACACTACAAAAGATTCCAGAATTCCGGAGAACTACGTGGCA
+ATTGATGACGTCAAACGGCAACTTCGATTCCTTGAAGATTTGGATCGTCA
+AGAGGAAGAATTAAGGGAAAGTCGAGAAAAAGAGTCGCTAATTCGAATGA
+GCAAGAATAAGAATAGTGGAAAAGAGACGATTGAAAAAGCGAAAGAAATG
+CAACGACAAGATGCTGAAGCGAAAAGGAATCGAGATGCGAATGCGGCTGC
+AATTGCAGCACTTTCCAGTAATAAAACTGTCAAGAATAAGTTCGTTTTTA
+GCGTGAAATTTGCAGAAAAATTATTTTTAAAAAATAGATTTAAAAAAAAC
+AATTTCCTGACCAAGGGTGTCATTTTTCGATTTTTCGGTTTTCAAAAATT
+CGAAAAATGAAAGTTTCGTTTTTCGATTAAAAAACTGAAAAACCGACACC
+TTTGTTTCTGAGATTTGGATTTAGAAATAAGCAAAAAAAAATTATTCAGA
+AAAAATTGTTTTACAATGCTGCAAAATCGATGAAAAAATAAAATAAATCA
+ATAACTAATTTCTAAAAAATGGAAAAAAATTTCGTTTTTTTCGAATTTGT
+ATTTCACAAAAAAAAATTTTTAGAATAAAAATTTTCAATTAAAAAATTAC
+TATTTAAAATCACTGAAAAAAAATGAAAAAAATAGAAAATTCAGAAAAAT
+AGCGAAAAAAAAGTTTTTTTCCAGAAATTTCGTTAAAACGATCAAGATTT
+TAACCCTAAAATTTAGATAAAATCAATTTCTTGTGGTTCTTAATTTAAAA
+AAAAAAACAGTACTTTCCAGTAATAAAACTTTCAAGAATAAATTCGTTTT
+TAGTGCGAAATTCGCAAAAAAAATTACGAAAAAGTGAAAATAGAAGCTGA
+AAGGAAAAATGTTTAAAAAATAAGAATATTTTCGACATTAATTGGTTTTT
+ATATATATTTTTTTGTAGAAGTTTAAAAAAATTACTAAAATCACTGAAAA
+AATTGAAAAAAATTTTAAAATCTGGAAAAAAAGCAACAAAAAATTAATTT
+TTCCAGAAATTTCGTTGAACTATTCGGTATTTTAAGCCTAAAATCAAGAT
+ACAATCAATTTGAACAAAATTTGCTTTAAAAATACTAAAAATTCGAAAGA
+AATAGAAAAAAAAAGAAATTTTCGAAATTTGGATTTATTGTTAGAGAAAA
+GCTGAACACTTACAAAAAATTAATTTTTTACGTTTTGAGAAAAATTTTTG
+AAAAAAAAAATCGATTTTTAAATAATTTTTAGAATTTTTTAGAACTATAA
+TTTTTGAATTTCAGTGACTTATAATCACAGAAAAAAATGAACGAAAAACA
+AATGAACATCTTTTCGGCAAAAAAACGTATTTTAAAAAAAAATTTAAATT
+TCTAGTGACTTTGAAAAAAAAACCACATTTTCCAATAATTTCCAGGAATA
+AACTAAATTTCTTTGGAGAAATTTGAAATTTATTTCACATTTCGAAAAAA
+TTTATATAGAAATAAAAATTTATATGAAAATAAAAAATTTGCAGCTCCTT
+CCAGTAATGAAACTGTCATTTGTTGAAAATTAGTTTTTTTTTAATTTAGA
+AATTCTCTTTTCGAAAAAAAAGGTTTTTTTAAAACTTGATTAAAAATTAA
+TTCATTTTTTTCCAAAATTAGGGAAAAAATAATTTCTAAAAAATTAGACA
+AATACACTTTTTTGTTGAAAAAAACAACATTTTCCAATAATTTTCTTTTT
+TTTTAAATTGCTTCCACTAAATTCACTTTTTGAAGAAATTTTTTGAAATT
+TTTACTGAAAATTGTTGGAAAATTATTAAATGTGCATTTTTTTGCAATTT
+CCAGTTGATAAACTAATTTCGGTTCAATTTAAAATAAATTTCGAAAACCA
+ATTTCAAAAAATTCATTTTTTACAATTTGTTTTTGTTGATAAAACGAGCT
+AGTTTCTACCAAAATACCGCTTTTTTACATTGAAAATTTAAATTTCAGAT
+GGGAAAACACGGGCGCCGCAACGACAGCACCTCGTCCACGAACAGTACGT
+GTAACAACTCGTGATCTACATCTTTTAGTCAATCAGGATAGCCGATTCAC
+AGGGTAGCGATTTTTTTTGTTTAAAAAATTTTTTTAAAAAACACCGTATT
+AAACATTGATTTTTATTGGAAAAAACTGATTTAAAAATTTTTCAAAAAAC
+TTTCAAACGAATGGTAGTTTTTAATATTTTAATTTTAAAAAATTCCAATA
+AAAATCAATTTTTATACGATTTAAAAAAATTTTGAAAAGTTATCCAATTT
+TCTCCTAAAAAAACTCATTTTTTTTCCAGAACATTCATCCGTGAAAAGAT
+GTCATACGGTGGTCCGGCAGTCGATACAACTATCTGAACTAAAGAAATCT
+CATGGAAAAAGGAGCGAAAATTCTGCTTTTCTCGTTTTCTTTTTTTAAAT
+TTAATTTTATTTTTCCACAAATTAAAACAATCACTTTTTTCCAGTCAAAT
+AATAATTATTTCTCATTTTTAAACGAAATGCTAGACATAAAAAAAAGCTT
+CTTTTTCAGCTTTTCAGCCAAAAATTTCAGATTTTTCAGAAAAAATTCAA
+CAACAAAAAATTGGCAAAGTGCAAAAAAACCAGAATTAGATATTAAAAAT
+ACAGGAAAAATCGAGAAAAATGAGTTACAATTCAGAAAATTAGGCAATTT
+TTTTTTCAAAATTTCTCAAAAACACTGAAATTTCGGTATTTTTTTCTCTA
+CTTGAGCACAACCTCGTGTTGCACCAATCGAACATAGTCTTTGAGCGTCG
+GTGGAAGTGGAAGCTCATCGATTATTCGCTGATAGACACCGTCGGCACCG
+GCGATTTCCAGATTTCTACGTTGGCGAAGGTGGATGGCGCGCTGGAAAAA
+TTTCTAATTTCGAGCTGAAAACTCTTTTATGAAAGCAAAATTTCATAGTT
+TCAATTCAAAGTTCGAATTCCTCGCAAAATTTCAGTCGGAAAACCGAAAA
+CTAGAAGTTTCTTGCTCGAATTTGAAATTTCGAGGGGTACGGTATCCTCG
+AAAGTACGCAAACACCGAATTTTGTTTTTTTGAAGTTTTGGCGCCAAAAA
+TACAATACCCGGGGTCTCGACACGACAAATTTTTAAAATTTTTTTGAGTA
+CTGTAATTTCAAACAAAAAGTTTTTTTTCGAATAAACTCGAATAATACGA
+TAAAAAACATATTTTAATAAAAACCGTGGCAACGAAAGTTTGAAAGTACA
+GTACTCTCTTCAAAGGCGCACACCTTTTACGCATTTAACTTTCGTGGCGA
+GACCCCGGGGATACCGTAATTTTTGACTCAAAATTTAAACAATAAATCCG
+TTAAAATATTAAAAAATTTTTAGATATTTTTCAAAAAGACTGTCGAAAAA
+TTGTTTTTTTATAATTTTTAGAATATTAACAAACAGTTTAAAAATTCCAA
+CAAATTTTGTTTTTCATACCGAAAAGAAGAAAAATGGACAAAATAGTAAG
+CTATTTTTGTGTGTCAAAGTGTCTTATTTCGGCTTGATCTACGTAGATCT
+ACAAAAAATGCGGGAGAAGAGACTCAGAGTTCTCAACTGATTTCGCATGG
+TTAAGAACGTGCTGACGTCACATTATTTTAAGGCGAAAAAATCCCGCCTT
+TTTTTGTAGACCAAACCGTAATGGGACAGCTTGGCACCACGTGACACCCC
+CCGATTCTCACCTGTTCGTGATTTTGGCGAACTGCCATTTCTTTCAAATA
+ATCGTCTAGCGGGGGACTCGATGCTGAAAAAAAAGTTTGATTCGTTAGAG
+GAGCACAAAATTCTGAAAATGCGTATTGCACAACATATTTGACGCGCAAA
+ATATCTCGCAGCGAAAACTACAGTAATTCTTTTTAAATGACTACTGTAGC
+GCTTGTGTCGATTTACGGGCATCGATAGAATATTTTTAAAAAAGAAGAAA
+AAAGAGGGAATAATACGAAGAAAAAAAGGAAAAAAATAAATTCATTTCAG
+AAATCGAGTTCGTAAATCGACACAAGCGCTACTGTAGTCATTTAAAGAGA
+TACTGTAGTTTTCGCTACGAGATATTTTGCGCGTCAAATATGTTGTGCAA
+TACGCATTTTAAGAATTTCCAGTTTTTTCAAACCTTTAAACTTACATTTT
+CGCGGTTTTTTGGCGCTCTCGGATTTCGGGGAACGTATACGTCGGCGACG
+TGACGTGGTTGAAGCAGGGTCCGTCGAACAACATGGCTCTTCGTCTTCCG
+ATACTTGGGATTCTGTTGATGTTGACGGTGATTCCTGAGGTTCCTCTAGA
+GCATCTGAAAGCTCTTGCTCATCTTCTGATAAATCTCCATTGGGACGTTC
+AACCAGGCCGGTGGTGGAAGGATCATTGATGTTCGGAATCATTACAATCT
+CCATTCTCGGAGTATTTGGAGTTTCTGGTCGAGCTATCGAGGAAAGTATG
+CGATGATGGCGGGGTCTATCATGATTAATCGTCCATTCGAGCACATATGC
+TGGTGCTGGAAGGATTGAAAATTGTAAAAACTAAGATTTTTTGGCCAAAA
+AAATAATATTTTCTCAAAAATTTTGAAATTCTCGACAAATATTTTTTACT
+ACTGCCGGTACAGAGAATGTAGATAGTTGAAGAGACACAGACATCCCGGG
+ACCCAAGGGACGGGGCGCGGGATGTCTGTGTCTCTTCAACTACCTGCACT
+CTGTGCTGGTAATATACTTTTTCCAAAAAAAAAACCTACATTTCGGAAGT
+AAAAATGGAAAATTTCGGAGTCTACACAATTGGAAATTTTAATTTTTAAA
+AAATTAAAAATTGTTTTAATTCGGAGTTTTAGACGGAAAAAATTATTAAA
+CTCTAAAATTTTTAAAAATCGAAAAAAAACAAGTCTGAGAGTGAAAAAAA
+TTAATAAATTTTGAACTGAACATTAGATATTTCGATTTTTTTTTGAAAAT
+CATAAATGTTTTCTCGCAAAATTCGGATTTTTTTTACCTGCTCGATTTTC
+AGTAGCCGGAGCTGTATTTCTGAGATTGGCACCATCCAAATGTGCTCGGG
+GCGCTGCAAATTTGATATGAAATTTCACTAAAAAATTAGGAACTTATACA
+AATTTTCTAAAAGAAATACTAATGTTAAGATAATCGAAAGTTTGGAGTGA
+CAGAAAAAATTGTTTCAGCTTCTAGAAATATTTTAATTTAGAAAAAAACT
+TCCAGAAAATTAAAATTTTTTTTTAGAACTTTTGAACATTTTTCCTGATT
+TTTCTTTTTTTTCCATTTTTTGGAATTGCTGGGAATTTCTCTTTTTTCCT
+TCATCCCACAGCTTCGCTTCAGCCTAGGCCTAAGCCTGAGCCTGAGCCTA
+TGCATAAATCTAAGCCTAAGCCTGAGCCTAACCCTATGCCTAAAACAAAG
+CCTGGACCTAGGCCCAAGTCTAAGTCTAAGCCCACGCTCAAATTTAAATC
+GACTCAAGTAACTACTTTAAAGTTGGCAGAAATATTTGAATTCAAAAAAA
+TTTTTAACCAAAAAAAAAATAATTTAAAAGAAATTGTTTTTTTTAAATAA
+AATCAACAATTCACCTGTAAAACCTTGCATTTCTCTCCAATTCAACATTT
+CTTGAAGAACGTCAGTTCTTGTTTCATTCCATCGACGAACATGATCTGCT
+ATAGTATTTCGAATATTTTGTTCATTGTTTTCTTGTTCTCTGGGATTATT
+ATTACGACCCAAATATTGATCCATGACGTCATCCAAGTGATTACGGGTTC
+TTTGATCTGCTGGGAATATTTATAAGCACTTTTTTAATTTAAAACATATT
+TTTTAGTGATTTTTTTTCGAACTTTTGAATTTTGAATTAAAAAAAAAAAA
+ATTAAAAAGTTAAATCCTGAGGGGAGCCAAGAAGTGGGCGTGTTTTAGGA
+CATACTCTTCACTTACGCTTTGGTCTACAAAAAATGCGGAAAACTTTTGC
+CCAAAAAATGTGACGTCAGCACGTTTTTAATCATGCAAAATCATTTGAGA
+GTTCTGCGTCTCTTCTCCCGCATTTCTTGTAGATCTACGTAGATCAAGCC
+TAAATGAGACACTCTGACACCACGTGGAAAATAAAAATCGAACATTTTCA
+AAAAAATTACTCAATTGATTGTCTGCTGGAGTTAGTTGGTCGATTCTGAA
+AAATATTAAAGTACTAAAAATTTTCCTTAGCAACATAGCGCGTTTGCATC
+AAGAAAGGCGGGATTTTTCTAAGCCCGCCCTTTAATGGATCATCAATTTC
+TAGGAAAAATCGATATTTTACACTAAAAGTGATCCAAGAAAATCAATAAA
+TCGGAAAATTTTCCGATTTTCCGTGCTTTTTTGCGAAGATTTATCGAAAA
+TGATTTCCATTAGAGCACGCTTGCAATTTTTTTCACCAATAGCTTTCAAA
+TTTCTTACGGTCTTGGATCAAAAAGTTGTCGACGCCGATTCAACTCTTCG
+AATTGTTCAGCTTGATGCCTTTGAACATGATCCATATACGTATTTCCACC
+TTTCATCACCATTATTGATCCGCAAATCTGACGATTGACACGTGGATTGT
+AGGCGTGTCGGCGAATGTCGCGGCGGAGTGCCTGACGCGCCAAGTAGGTC
+AACGTGCGGGGACCACTAAAAAATCCGGGTTATTGTGATTTCGTGGTGAG
+ACCCGAAAATAGTAGAATTTCCTCGTACATCCTGTGCCTAAGCAGGTTTT
+CAGTTTTTGATGGGTTGTTACCTTCATACACCTACCTGCCTTTGTGACTG
+CCTCCCTGCCTGCCTAAATGTGTGTATGCCTACCTACAGTCTGTTTATCT
+GCCTCAACGCCTTCATACCTACTTGCCTACCTTGCTTACATACCTGCCTA
+CGCGACTACCTATCGGCCTACCGGTTGGCAAGTAGGAAGGCTAACAGGTA
+GGTAAGCTGGCAGGCCTGAAATTTGCAATTTTTGCGAAAAACCGAATTAC
+CTTTCGAAAGGCGTAGGCGTTGAGATCCGTTCCTCCTTCGGAAGCCTGAT
+CATTGGAGAAAATGTCATTCTTCCAGGGACGTCATACACAGTACGATGCT
+TGGAAACTCTTCTGTATCGGCAAACCTGAAAACCTTTAAATGTGGAGGAG
+CCAAGAACTAGACGGAGCCTGTGTAAGGAATATTGTTTCCGGAAACACGG
+ATTTTCAAATTTTAGGCTCCACCCACTCACCACGCAAAATTTCATTTTTG
+GCCCAAAAAGTAAATGTGCAGAAATTGTATTTCAAATTGTAGAAAAACCA
+AGAAATGGGTGGAGCCTGCCTGCCTGCCGGGCTCCGCCCACTTCTTGCCA
+AACCATACCCCCTGTATACGTGGCATGACGAGTTGTCCTCCAACATTCAA
+CATTCCAAGCATTCGTTTCAACAACTGAGAATCATCGGCAACGAATCCGA
+CAAAAATTCGATCATATCGATTTTGATGAGCTTCAAGAAATTTGACATCG
+GTGATGTCGCACACTTTGAGCTCCGGCCGAGCCCAGCCGACAGAGCTCGC
+TTCGGGTGTAGTTATCCATTGATCAATGCATGTTTCCGAGTAGGTGACGA
+GATTCTCGTAGAGTTCGATCCCATGATTTATACCAGTTTCACCTTAAAAA
+TAGGGTTGTCAGGCCACGCCCATTTTTAAAAAATGAATTAAAATTTTCTG
+AGAAAAAATTTCAAACTTTGGTGGGGCATTAAATTTTTTCACATAAATTT
+TTTCGGCGGTAAATTCAAATTTTTTAAAAAATTTCTTTTTTTTTTGGCGG
+GAAATGTGCCGCAAATCAGAAAAACTGAAATTTCTACAAAAAAAGTTGGT
+GGCCGAGTTTTCTCATTTTGTGGTCAGAAAACTCGGCCACCGATTTCTTT
+TGCGGCCCTGTGATTACTTAAAAAAATCGGTGGCCGAGGATTTTTATTTT
+CGCGGCCACAAGTAATGAAGATTGCACAAAATTGATAATAGGGAAAACGC
+GGCCACGAAGTCTAACATGTGCCACGTGGCCGTTAAAAAAAAGCCGGTGG
+CCGAGTTTTATTATTTTTCTAGGCCACGTAACCAGAACTCACCCAATAAA
+ATGCCAGCAATCGTACTTAAATACCCTGAACCAGTTCCAATATGAAGAAA
+CGAGTGTCCTTTACGCAAATCCAAATAATCGAATAATTTCGCATAAATAT
+CAATTGCTCCAACACGAAGTGCTCCCGGATAGAATGGACCGCCCGGTTCT
+GTGGAGGTCAACGACGGAAGACGTGTAAATTTCCGTTCACTAATCGGAAG
+AAAATCGGATCGATCGACAAGTCGAAAGGCTCGTTCGATGTTTCGACGAC
+GGATTGTGTCGTTTTTTACGAGAAAATCGATAAGATCGTCGTTTTGGCTT
+TCACTATTGCCCATTTCTGGAAAATCGATTTTTTAAAATTTTAGATTTAT
+TTATTGATTTTAAATAAATAATTAGAGAGCAGTCATGTGTTTTTCCTTGT
+ATATTTACGAGAGAAATCTCAAAAAATTATTCAAATAGGAAATTTTACGC
+CAACAATAAAATGTAGAGTGGTGTGCGCCTTTAAAAAGTACTGTAATTTC
+AAACTTTTTGGCGCAAAATTTTAGAGTAGTTTTCTTTAAATTAAAAATTC
+AAAAAAAAAACAAATCAAGATAAATACAAAAGTTTGAAATTACAGTACTC
+TTTAAAGGATCACACCATTTTGCATTTAAAAAAATTTGTCATGTCGAGAC
+CGTAATTTTAACGCAAAAAACGTGAATTTTCGCGTCTGTGTAAAAGAAGT
+TAGTTAAGGAGAAAAAACAATTGAAAAATCAACAAAAATTGAACTTTCAA
+CGGAAAATCAAAAATCGTTGCGAGTCAATAATTTTTTAGCTTTGAGGAAA
+ATAACCCTTAAACTCAAAAAACAATTAATCGACTCAACATCAAAATTTCG
+TTACAAGACCCAAATTAAAATTTTTTATTTTGGGATAATTGCTCCTAAAA
+TTAATAAATTCCAGAGAAACGAGTAAATCGTGGCGAGACCCACTAGCGTG
+TACCTTTAATTTCGAAATTATTTTGGGCTGTTCATCACGAACACACGTGT
+TGCCTAGCTACCAAATTCAAAAAACGAAAAACAAAAAAAACAGGTTTCTT
+TGAAATGAAAAATCGATAATCAGCAACGTGGCAAGATGTCTCAAATTATT
+GGAAAAAAAAAACGTTGAAATTCTCAGAAAACGGACCGTTCTGTGGCAGA
+ATTGTGAACGGCGTGCAAGGCCACGACCCGTGGAGAGCGCGTGAGAGTGC
+AGAAAAAAGGAGGCGAGAGAAAACGGCTGACCCGTGGATAGACTTTGTGG
+ATTCAGGAGACGCAGAGCGACCGTGAGAGACCCAGAAATATATGCAGAAA
+GTTAAGGCGTGCAATAGTGTTGGAAATTATAATAAATGGGTACGGTAGGT
+ATGACCTTTCGGGATCTTTGTGGGTCTCGCCGCGACGAGTTTTCAAGGTG
+CATAAGGTTTTTGCGATGGGTCTCGTCACATAATTGTAGATTAAAATTGT
+TGATTCGAGATAAATGGAAATTCGAAGCGTCTAAAACAGTTAGAACTTTT
+AGTTTACATTAGGTTGAGCTCAACTGTCCAACCCCGTCAAACTTTTTCCA
+CTTTTTTTTTACTTTTGCCTTTATGTCCTTTTCGGCCGTTTTCCTGGGGG
+TTTTTACCAGACTACGAAATATCCTAACTTGGTAAGCCTCAGCCTAAGCC
+GAAGCCTAAACCTTGGCTTTCAACTATACATACACATTTCCTCCTTTTTA
+AACGATATTAATTAATTTACAAAACACCAAAAAAATATACAAAAAATGAT
+TTGAATTTATGAGTTTCCCGCTAAATACCTACCGAGACCCAACTTTTGGC
+CGTGGAGCGCGCTTGCACTTAAACTTCAATTTTTCACATCCCCATAATAA
+CTTCCTTGTTTTAAATTGTTTTTCCCTATATTATTATTATCCTTATCACG
+AGATGCCCTTGCAAAACACATTGTAAAAATAGTATTCTCAACTGATAATA
+ATATTTTGTGTACCCCACGATAGTCCTTCTGGACCATAAAAATATTGATA
+ATTACTGATAAGCTTTCTCTGTGGTTTCTGTAGTTTTGGTGATATTTTGG
+GCAACAAATTTATATTATGGAAACACGGAATTCTGAAAATGCGTATTGCG
+CAACATATTTGACGCGCAAAATATCTCGTGGCGAAAACTACAGTAATTCT
+TTAAATGACTACTGTATCGCTTGTGTCGATTTACGGGCTTGATGTTGGAA
+ATTAATTTATTTTCGAATTGTGACAGCGATATTCAGTTTTCCTTTGTTTT
+TTTTTTTCGTATTATTTTGTTATTTTTATGCTTTCTTTTAATATTTTATC
+AATTAATGAATGATTTCCGTAAATCGACACAAGCACTACAGTAGTCATTT
+AAACAATTACTGTAGTTTTCGCTTCGAGATATTTTGCGCGTCAAATATGT
+TGTGTAATACGTAAAGAAAGTTTGAAATAATTGTTTTTAAATAATTTCTT
+ATTCATTCACTGTCAATTCTCACCGAAAAAAAAAATCCAAGTTCCTCCCG
+CCAACTTGGCACGATGCCAAAAGGTTCTCAGGCCCATTCATGTCATTCAA
+TCCATTCAAATGAACGACTTTTCGTTCAGTTTAGGCTTCTTCTTTTTCCG
+GTTTAGTACTTTTTCAAACCGAAAAAAAAAATCCCAAATTGAATGCAAAT
+GTGCTCTATTTGGAATAGACTTCACCCTATTTCGGAATTTTTTCCGATTT
+TCTGAAAATCTTTAACACTTTTCTAACTGTTGCATTAATGACATTTTTCT
+AGAAATTCTACTGCAAACGCGCTCAGTTGCGAAAGTTTTTGGGTCTCACA
+ACGATTTCGGAAGAAAAACGTTTTATTCGTTGCGAGACCCGGAAGAGCCC
+GGTGGAGCGCGTTTGCAATTTTTTTGGTTTGAAAATTTTGCGCAACGATG
+CTCCAAAATAACACCTCGCGAATTTTATCGTTTTTTTAAATTATGACTTT
+TCCGGTCCCAGAACGAATTACAAAAGCAATTTTTATGAAAAATCGTTACA
+AGACCACAAAAAAAAGCGCAATAGAGCGCGTTTGCACCTTTTTTTCTTGG
+AAAAGTCTCGTTTTTTTCTCGGTAAATTCACTGTGACATTGACCTTTCTC
+GAAAAACGAAAAGTGTAATGGAAAGTGAACAAAAGTGACAATAATCTGGT
+GAATTGCGTTTTGTTGTAATATTTTTGTATCTTCTTTTCTTTTTTTAATC
+TGCGAAAAATAGAAAAGTTTTGGAGAGAAAGTGATTTTCGACGAAATTTT
+CCTGATTTTGCTAAAATTGAACAAAAATTGTCATCATTTTCTGTGGGGTT
+TCTCAAATGTTTTCTTAAAATTTATGCGCCTTTAAATTTGGGGGATTACT
+GTAATGTTTGTATTTTTCAATTTTGTTTCGGGAACACAAAATTCTGAGAA
+TGCGTACTGCACAATATATTTGACGCGTAAAATATCTCGTAGCGAAAACT
+ACAATGGATTAAAATTTAATGAAATATCGTTATCACTATTCGAAAAGAAT
+TTCATTATGAAGCCCGTAAATCGACACAAACTCTACTGTAGTCATTTAAA
+GAATTACTGTAGTTTTCGTTACGAGATATTTTGCGCGTTGTCCCCGTAAT
+AGTTTAACTTTTACCACGTGGCCGCCAGAAGAAAAACTTCTGCTACCGGA
+TTTCATTTCCTCGGCCACAAACCCTTTTGACCCCCGAAAAAGTACATAAA
+AACAATTCCGGGGACTGGGTCTCCAATCTCTCGCCCCCACTCACTAACAA
+GGGGGACACCCTCAGAAACGAATGCCGTCTAACCGTCTGCACCCTCTCTC
+TCGTCGCTCCAAATTCTTGGATCAATGCCAACTAACACGCAGTGTCCCCC
+CTCCTCCTTCATCCACCCAAATGTTTCATCACTTCCCGGCCACCGCAGGC
+TTCTCTCTCTTTCTCTAAATCTCTCATAAACTACTGTCTCTCTCTCTCTG
+CTTCTTTTGCTCAATTGTTCTTCTTCATCACTACTATTTGCTCAATTTTC
+GTAAATATTTTATTTTAAAATATCCCTTTTTCCTCCCCCCGCCTCTCTGC
+TTCTCGCTTGACGCGCCACATACACTAAAAAAACCGGTTTTTTCTATCTC
+TCTCCGCCCGATCATTGAATAGATAGTGTGTGCTGTACATCAAATTTCCA
+TGGAAAAATCGCGCCGAAATTCCAGAAAATTCCACTTTTTCTAGAATTTT
+CAGCGATTTTTTTCGGTTTTTGAATTTAATACAAAGCGAAATTCCGTGAA
+AAATTAATTTTTCCTCAATTTTTGACGAATAAAAAATATTAGTATTGTTT
+TTTTTTCAAGAAAGTGTGATTTTTTCACAATTTTCTATGGTTTTTACGGA
+GAAAATCTTGAAATTCCACAGAAAAACTTGACAAGTCTTTGAAAATTAAT
+AAAATTTCACCGTATCTGCCGATCGTTGCAAGACACACTCCACAAAAGAA
+GTCGTGCGCCTTTAAACTGTGTACGGTAACTATATTGATTTAATTTTTTT
+TTTCGATTTTGCGTCTATTTTTCCAATTTTTCTCTGATTTCGAACGATTT
+TTTGCATTTTACCTCAAAAAAATTAATTTATTTAGATGATAAAGTGGAAA
+TTGCTGATTTTTTACAAAAAAACACTTAAAAAACGAGTTTTCTCATCAAT
+TTCAGTTGTTTCTGGCATGGCTCATTGTTTATCGACACCTGCTTGTTTTT
+CTCCTCCTCTCCCATCAATTTTATGAGTTTTTCTTCGAAATTTCTCCATT
+TTTCCCGTTCAAAAACCGCCAAAATTCGCTTTTTTTTTTCCAGAATTCGC
+CTACTATAGCACTACTAGATGTGTTAATTTGGAATTATTTTTCAAAAAGA
+AATGTATCCGGACGGGCTAACTGAAAATGAGAAGCTCAAAGTGAAGGAGC
+TGTGCACTATGGTCAATATATCCGATGAGGATGCGATTAAATTGTTAAAA
+GGTGGATAATTAAGCTGAAAAGTGGAAAAAAAAATGCATTTTTTACCTAA
+AATTTACCTAAAAATTGGACCAAAACGTCATAAAAATACTGAAAAGTCAG
+AAAATTGTCTAAAAAAACTAATTTTCGCTAAATAATTCCAGAAAACGACT
+GGGACATTGCAATTTCATCGCGAAGAGTGTCGAAACAAGAGGATAAAACA
+TTGGTTCCGGGCACTTCGAGAGGTAAATTTTTGAAAATTTTCAGAATCAA
+ACTGAAAAATAGATATATTGTGTGAAAAAATCCATTTTCGCCGTAAGAAA
+AGTGAATTTTGAGCGGTTTTTCAAATTTTAAACTGAAAAAAAAAATCAAT
+TTATCTGAAATTTTGCTCTTTTCGGCGGGTTTTTTCTCAAAATTTGATGA
+AAAAGTTCTAGAAAAACGACAAAAAAGCCTTTAAATGTACTTTTTTCTGC
+GATTTTTTATCTTAAATTTAAAATTTTGCGCGTCAAATCTGGTGTTTTGA
+CTCCGCCCACTAAATTTAAACTTTTCGTGAAAAAAAAATGTTTTTCTCCG
+ATTTTTAATTGTTAATTTAGGCAAAAAAATACAAAATTTGCCCAATTCAC
+CTATTTTTTCCAAAAAATCACAAACTTTGCGCGTAAAATCGGGTGTTTAT
+GCTCCGCCCACAAAAATTTCTTAGAATTCGATTTTCGGCGGATTTTTTCT
+CAAAATTTGATGAAAAATCTGAGAAAAACTACAAAAAATCTTTGAGCTTT
+ACTTTTTCTCTGCGATTTTTATCTAAAATTTGAAGTTTTGCGCGTCAAAT
+CTGGTGCCTTGGCTCCGCCCACAAAATTTGAAGTTTTCGTTTAAAAAAAT
+GTTTTCACCACTTTTTCGCCGCTTTTTCGCCTGAAAAATCCCAATTTTTT
+TGCAGAAGAAATCGATTTGGATCGATTATCGAGTCGTCTACGTGTTCACG
+GATTAGCCTTCTATCTTCCAGATTTTGGAGGTTTTCCTAATGAATTTCGA
+ACGTTTTTGGAGAAGGATTTGATAGAGACGCAGACACAGAAGAGACTGGA
+GGCGTCCAGTAAGTTGTTTTCTGGAAAAATTGAAAAAAAAATTGAATAAA
+AAAAATGATTTTTTTAATCGAAAAAAAAAGTTTTCAAAAATAAAATTGGA
+AAAGGTGAAAAAAATTGAACAATTAAAAAAGAGCGACAAATGAATAAAAA
+AAAACTTTTTTTTTTTCGAAAAAAAAGAAAACAAATGTTTTTTAATCGAA
+AAAATAAAAAACGAAAAAAAAAGGAAATTTTTTTTACAATTAGAAAAAAA
+AAATTAAAAATGTATTAAAAATTTTTTTTTTTGACATTTTCTTTCGCTTT
+TTAATAAGTTTTGACTAGCGGGCCCTGCGGGCCCGCCAGTTGCAGGGGGT
+GTAGGGCGAGTCCCCCAGTCGGGCGTAGGTTCTCGGCTTCGCCTCGAACC
+TGTCAGAGGATTCGCGACAATTGCAGTGAGTCAATGGGAGGAGGGGAGAC
+CCACTCATATTTTATAAAATCGAACATTTCTATTTGAATCCCGAGCACTC
+ACAAAAAAACGAAAAAGTTTGTCAGTTGGGGGAATCGAGCAAAAGAGCAA
+ATTATTCACAGCCATACGCACTAACCACTCGGCCATGCGGGAGAGACCTG
+TCACAGAAATGTAGGGAAGGAAAATTTCTGGGGGGGGGGGGGGGGGGGGG
+AGTTGTCTTTCGATTCCGTTTTATTCAATAATGACAATTTGGGGAAAGAC
+GTTTGAAAACCGTTTATCACTGATAAGTCAGCAGGAAAACAATTTTTTGA
+AATTTTTTTATAGCATTGTACTCATTATTTAATTCCCGAAAGAGAGCCGA
+AAAGTTGAAGGTGTTATCTTGTAAATTGGTTTATTTGAAGAAAAAACAAG
+TTTTGGCCTGAAAATTTTGAAAAAATAATATCTCTTGGCAGAGCATTGCT
+AATGCGACGAAACTCCAGCTTCCATTAGATAAAATCAAAAACTATGAATC
+AGAAATACATTCCGCAAAACTTTAGTGGAAAAAATGTTCAGGAGACCCAG
+GAAACCACTCCCCCCAGTACTAAATTTTTGAATTATTTTTTCTTGAAAAA
+TTTTCCCACTGAACTTTTTACAAATTTTATATGTCTCGATGCGTCTTGAT
+GAGACCTACACGTCAATTTTTGGAAAACTAAGAAAACTTGAAAACTGACC
+GAGTTATGATTGAAAAAGTAGATTAGCAAAGATGGGAAAGTGTGCAAAAT
+TTGGCACTTATTCGTCTTGCTCGGCCGACTCATAGTACTTTTTCCAATTC
+TGAGTTAAAAATCGTGTTCAGCGTACTTTTGTACGTGGGATAAAGAAAAA
+AAATATCAAAAAAGATGAAGTAGAACTTGAGATAAAGACGAAAAACTACT
+TTTTCGGAAAAAATTTTTTTTTGGCAAAATGGCATTTTTTGGCCTTTTGT
+TTTATCACAACTTTTTGCCTTTTGCACTTATGAACTCAAACTTTCTTTCA
+AAAAATCCACCTCTCTGAGTAGTATCTTGCACATAAATTTGGAACAAAAC
+CGAGCAAAACCCGAATTTTAATTCAATTAAAACATGGTTTTTTGGGGGTA
+AAAAAAGCAACAAAAAATTTTTTCAAACTGGGGAAAGCCGCCCTGAGCTC
+AGTTTTGCTCCAAACTTTGTGCAGTTTTTTGCTCCCCCGTGGGGTGAAAT
+ATTTCTAGTAAGCTGTCAAATATTACAAAATTCAGTCAAACGGCTCTGGA
+GTTATTAATGAAAACGCAGTGTGACATTTTTTCGCAAGCCAAAAAAAACG
+CGAAAAAACGCGAAAAAGGGGCGGAGTCTGTACACTCGGCATTTATTAGA
+GGCTGCTTGGCAGATTTTGAAATATCGGAAAAACTTTAAAAGTTCTTTTT
+TTTCCAGGACACCTAAACTGGTGGCATCAATTCGGCCAAAAACTCTACCC
+GCTATCAACTACTGGAGACGGAAATTGCCTTCTTCACGCCGCATCGTTAG
+GTAAATGGTTTTTCAGAGCGAAAAATCGGAAAATCGCTAAAAACTTACTA
+TTTCCACTGAAAAAATTGTAGAGATCGCTCAAAATTTCACTATTTTCTGA
+ACATTTTGATAAAAAACGACAAAACTATTTCAAAACGAGCCCCGAAAATT
+GTTTTTTTACTAAATTTTTTTTGGAGAAGTGCAAAAATTTAAATTTTTGA
+ATTAAATCTTTAAATCTTCAACAAAATTTAATCGTAAATTTTCAGGTATG
+TGGGGAGTACATGATCGTCAGCTATCACTTCGTGAAACTCTCTACGAACT
+TCTTACAAATGGCGCCAGAAAAGAAGCAATCCGACGGCGATGGAAATGGG
+TTGAGAATCATATGAATCAGGTAATTGGCGAGAGAAGAATCTGTGAAAAA
+TTTCTTAAAATTCGGTGAAAAATGATCAAAAATGAGCTGAAAACCGGTCA
+CGTAGTTGAAATCCGCGGAATATGAAATTCCCAGAGGAAACAATTTTCGT
+GGATTTCAACTTCGCGAATTTTTCTCAAAAAGCTTGAGTAAAAACTCACG
+GAGTTGAAATCCGCAGAATTCGAAATTCCCAGAGGAAACAATTTTCGTGG
+ATTTCAACTTCGCGAATTTTTCTCAAAAAGCTTGAGTAAAAACTCACGGA
+GTTGAAATCCGCGGAATTCGAAATTCCCAGAGAAAACAATTTTCGTAGAT
+TTCAACTTCGCGAATTTTTCTCAAAAAGCTTGAGTAAAAACTCACGGAGT
+TGAAATTCGCGGAATTCGAAATTCCCAGAGAAAACAATTTTCGTAGATTT
+CAACTTTTCTAGATTTTTTGCCAATTTTTTATTACATGTTACAAAAAAAC
+GGCTGTAAATACTCACGGAGTTGAAATCCGCGGAATTCGATTTTTGTAGA
+TTTCATCTTTTCCAGAATTTTCCAACAAAAAAAACCGGAAAAAATTATCC
+GACACTCCATGGAATCTAGTTTTCGGAGATTTCAACATCGAGAACTTTTT
+TCGCACATTTTTTTGCATTTTTAAAAAATTTCACCAATTTTCCAATTAAA
+ATTTTTTAAATTTCCAGAGTAACGGTCTCGCATTGACCCTCTCGGAAAAT
+GAATGCTTGAGTAAAAACTCACGGAGTTGAAATCCGCGGAATTTGAAATT
+CCCAGAGAAAACAATTTTCGTAGATTTCAACTTCGCGGAGTTTTCTGTCA
+ATTTTTTGAGATTTTTTCTCAAAAAGCTTGAGTAAATACTCACGTAGTTG
+AAATCCGCGGAATTCGAGATTCCAGGAAATTCGATTTTCGTAAATTTCAT
+CTTTCCCAGAATTTTCCAATTAAAAAAAAACGGAAAAAATTATCCGACAC
+TCCATGGAATTTAGTTTTCGGAGATTTCAACATCGAGAACTTTTCTCGTA
+GATTTTTTTGCATTTTTTAAAAATTTCACCAATTTTTCAATTAAAATTTT
+TTTAAAAAATTTTCAGAGTAACGGTCTCGCATTGACCCTGTCGGAAAATG
+AATGGGAACTCGAATGGGATGTTGTACTCGGATTATCATCTCCATTACCC
+CGTAAACAAGAGGATAATGGCTCAAATTCCACAGATCAAATCTACGAGAG
+TCTTGAGGCAATCCACGTGTTCGCGTTGGCTCATGTGCTCAAAAGACCAG
+TTGTGGTTGTATCGGATACGGTAGGGAATTTTAAAATTTTTTAATTCTTC
+AAAAATTTATTGAAGAGAACAGTAACAAAAAATTTGGTTACTTGTGAATT
+TTACAGAAATATAGAAAATTTTAATTTAAAAAAATTTCGAGATTGGTGAG
+AATCAAGGGTGTCAAGTCCCGTGTCCCGTTTGTCCCGTTGTCCCGTTTTT
+TGAGTGTTTTTACGGGAACGGGACGTCTTTTGTCCCGTTTTTGAGCGTTT
+TCACGGGAACGGGATGTCCCGTTGTCCCGTTTTTTGGGTGTTTTCGCGGG
+AACGGGACGTCCCGTTGTCCCGTTTTTAAAATTTTCACGGGAACGGGACA
+TCCCGTTGTCCCGTTTTTGTCATTTTTACGGAACATTGACACCCTTGGTG
+AGAATAAAAAATCAATAATACACATAATTTTTGGAAGAAAAATCGATTTT
+AAAAATGAAGCTTAACATTTTTTTTCGAAAGAAAAAAAGTGTAAGAAGTT
+TATCAAAAAAAAAAACATTGAAAAAAATATCTTCAAAAATGTTCAATTTT
+GTTTTAAGGTGCAACTATTACAAGAGCACACAATTCTTAGAATACGTATT
+GCGCAACCTATTTGACGCGCGAAAACTACAGTAATACTTTAATTGTCTAC
+TGTAGTGCTTGTGTCTCGATTTACGAGCTCGATTGATAGAATATTCAAAT
+AATTTATTTATCGATTTAATATTCAAATTAGGCAAAAAATGAGAAAAAAT
+ATACATGTGAAAAAATTAATTTTAAAAATAGAGCCCGTAAATCGACACAG
+TAGTCATTTAAAGGATTACTGTAGTTTTCGCTGCGAGATATTTTGCGCGT
+CAAATTTGTTGCTTAATACGCATTCTTAGAATTTTGTGTTCACATAATAC
+GGTTTTTCAAAAATTTTAAATCTTCATAAAATTCATCAATAATAACTAAA
+ACTTAATCAAAAAAAAATTTAATTTTAGTGTAGTCATCAGAAAAAGTCCA
+TCAAAAAAAGTCCATCAAAAAACCATCAAAAAAAGAAAATTGAAAAATTT
+GAATTAAAACATTTTTTTCGAATTTTTGAAAATAAAAGTGTTTGAATATT
+AAACGTAATTAAAAAAAAAGATTTTCCTTTTTTAGAAAAATCTATTCATA
+TTAGAACAGTCGATTTTATAAAAGTATCGATTTTTTTATTAATTGGATTT
+TTTGTAAAATAATAATCGATTTTGAAAATAAATTGCTTAAAATATTGTAT
+TTTTTGACAGAAAAAATGTAAAAAATTTATCAAAAATAAATAAAATTGCA
+AATAATTTTACCTACAAATTAATTGTTTATTAAATAAAGTTTAAATAAAT
+TAGAACAGGAGTAAAACGAGTTTTCAAAATTATTCTTTAAAATCTCGGGT
+TCTTTTAATTCAAAAATTCTTTTAAAAAAAACTCAATAATTACGGATTTT
+TCAAAAATTCGAAAAATTCAGAAATTCAGAATTTGGATAACATAATTCTA
+GTTGACTTCCAAAAAAATGATATGTGACTTACTTAAGGTACAACTAACAT
+TAATTTTCCAAAATTCTTATGGCTGCTTTAAAACACGCCAATGGGGTCAT
+AATGACCGAATATTATGTTTAAAAAAATCAAAAAAAATTTTCTGATTTTA
+TATGATTTTTTGAAAATTGGAAAAATCACAGTTTTAACCTAATTATTTTT
+GAATTTCTGCCAATTGGATTTGTTCGGTGCAGCGCGCTTGCATTATTTTT
+ATTTATTTATTTTATTTATTCTCGTTATTTCACTGATTTTCTTCATTTTC
+TATGTTTTTTTTTCTCGGAAAATGAAAGAAATAAACAAGACAAATGCGAA
+ATGTTTGTTAAAAAGTAATTGAAAATGCGTAAAACTGTGATATTCTGAGT
+TCCGACGACGAAGAGCCTGAAATTAGTATATTTTTCAGTTTCACTCATTT
+TCAATTACTTTTAAACAAACATTTCGCATTTTTCTTGTTTATTTCTTCCA
+TTTTCTGAAGAAAAAACATAGAAAATGAAGAAAATCAGTGAAATAACGAG
+AAAAATATATATAATTCATTAAATAAAAATAATGCAAGCGCGCTCCACCG
+AACAAATCCAATTGGCAGAAATTCAAAAATAATTAGGTGAAAACTGTGAT
+TTTTCCAATTTTCAAAAAATCATATAAAATCTAGAAAATTTTTTTGAATT
+TTTTTATCATAATATTCGGTTATTGTGGCCCCATGGGCGTGTTTTAAAAC
+AATTTCCCCACTGAGCGTAGTCCACCTTTGAAATGTTCTCAAAAAATGAA
+AAAAAAACGAGTTATAAAAATTATTTTTTAAAAATCCAATATTTTAAATT
+AATTTTTTTTTGCAGATTCTGCGAAACGCGAAAGGCGAAGAACTGTCTCC
+AGTGGCTTTTGGTGGAATATATCTTCCATTAGAATGCCCACCATCACAAT
+GTCATCGTTCACCACTTGTTTTATGCTATGATTCTGCTCATTTCTCACCA
+CTTGTACTCATGAGAACAGAGACTAACAATAAACGTAAGCAATTTTTTTT
+TTGAGAAAAAATATTTTCAAAATCATTTTTTAACTGAATTTTCAAATTTC
+CCCCCCCCGTCCCCCCCATTTTTTTCGAAAAGTGAATTGGAATTTTCCTG
+AAATTTGCACAAATTTTTTTTTGAAAATTCAAATGTTCGTCAAATAATTA
+TTTTATTCGAAAAATCGACATTTTTCCAAATTGTAATATTTTTATTCTAA
+AAATCCAAAATTTGATTTGGTAAAATTTCTGTCAACAATCAATTAAAAAT
+CCAAAATTTTCAAAAAAATTGTGATTTTATTCGGGAAATTCGAAATTTCC
+TATTTAAAATTGGATAAATCTAAAAGTTTTCGATTTTATAATTTTTAGGA
+AAACAAGTTTTCAAATTTTTTTAATTATTAAAGTTTTTTTTTGCAATTTC
+ACTAAATGAGCCAAATTTTAAAAGTGGAGCACCGAAATTTGAGACTTTGC
+TTTTTTAGACTCAAATTGGTCCAAAACTACCGAATTTTGTAATGATACAT
+TCTGAAAATTTCTCAAAAAAAAGTTATGGCTGTTTAAAGTTCGGCAAAAT
+AAGGCCCATTTTCAGCTAAAATCAAAATTTTTTCCAACTTCTAGGTGTCG
+CAACGTCTGGACCCTAATTTTTATTTATTCATCACTTTTTAATAAATATT
+GTGGCCTTTGATTGGGCGTTTAATCGTTGTTTTAAGTACATTTATGATCT
+TTGGAGTACAAATAAACGTTACATTTTGTACCCCAAAGACCATAAATGTA
+TTTAAATCAACGATTAAACGCCCAATCAAAGACCACAATATTTATTAAAA
+AGTGTTGAATAAATAAAAATTAGGTTCCAGACGTTGCGACACCTAGAAGT
+TGGAAAAAATTTTGATTTTAGCTGAAAATGGGCCTTATTTTGCCGAACTT
+TGAACAGCCATAACTTTTTTTTGAAAAATTTTCAGAACGTTTCATTACGA
+AATTCGGTAGTTTTGGGCCAGTTGGGTCTAAAACAGCAAAGTCTCAAATT
+TCGGTACTCCACCTTTAAAGAATTCATATAATTTTCTAAAACAACATATT
+CTGATTTACAGAAATACATTTAATATCAATATGAATTATTTGAAAAATCA
+AAAAATTTATATTTATTTTCAGAAATAATTCCGATAATCGATGTGAACCG
+TAACCTGCTGCCTGTCCATTTTGCAGTTGATCCAGGAGAGTCATTCGATT
+GGTCCAAATTAGAAACAAATAGTAATACACAGACAACTACTGATATGTCA
+CAAATTGATAAGCTTGCGTTGATTAGTCAATATATGGATATTATTAGGTA
+AGAAAATGAGAAAAAGGATTTTTTCAATTTTTTTTTCTAAAAAAAATATT
+CAAAATATCGTTAAAAAGCCAAAAATGTGTACGTTTTAATTTAAAAAATA
+TTAAAATTTTTTTGTCCCAAAATTAAAATATCGAAATCAAAATGTTTCCG
+ACATTTATATAGAAATTCTGGAAATTTTTTTAAAATCGAAATCATATTTT
+GAATGAAACTACAGAAAACAGCGCCAAAAAAGAAAAAAAATCGTTTTTTT
+TTTTCGAATCTTTCATTACAAATATTTGAAAAAACGATACAATTATGTTT
+CGCGAAAATTTTTTAAAAAAACTTTAAAAAATTATTAAAATCAGCTATTT
+AATCACAAATGAGAAATATATCGGAAATCTGGAAAAAATTAAAAAAATTT
+TTTGCGTATTTGTCTGAATTTATTTTACAAATACCAAAAAAAAATCAATT
+ATTGTTGGAAAAAATTGAAATACAACGGAAATCGAATTATTTTTATTTAA
+AAAGAACGAAAAAAAATCCAGAAACCATCACAAAATTATTGGAAAACGAG
+AAAGCTGATTTTTCGCTAAAGTTCAAAAAAATTTACAAAAAAAGAAAAGT
+ATTAAAATCGGTAATTTTCCCAGCTTGAAAAACTGAAAAATTCGAGTTTT
+CTAAAAAAAATTAAAAAAAAAAATCAAAATATTCCTCAATTTTGGAAAAT
+TACGGAAAAAGTAGTTTTCTTTAGCTTTCGGCCAAAATTTTATCATAAAA
+ATTTCCGGAATGCATAGTTTTAGAGAATAATTTTAAATTGAAACACTAAA
+TTTTTTAAAAAACTTTTTTTTTTGAAAATCCCGGATTTAAAAAAAAATAA
+AATTTGAATTTCATATAAATATTTTGTTAGGAAAAATAGTTTCTAAACAA
+AAATTTGAAAAAAAAAATATTTTTTTTTTCATATTCTTTGAATAAAAAAA
+ATCTGAATTTCGAAACATTTCAGATTAGACGTTCGTCGTGGCTCAATCCG
+TAGCTCGCGGAGAGTTCGAAGTGCTCACGCGCAACTTCTCACCGAATCTC
+GTGGTGAAAATGGGCAAAATTTGCCCCAAAAATCAATTAAACCAAGAGAT
+TTAAGTGCACATTCTAGTGATGAACAACCATCAAATAATGCAAAAGGAAT
+GACATTAGCATCAAGTGGAATTGGTTCTGGAAGACATGAGAAATGGAGAT
+TAATCAATGAAATTCGGTAAGCATTTTTTTTTTGGATTTTTGGCCTGGAA
+AAAATTTTTCCAACAAAAACTTGAACAGAATTTTTGAAAAAAATGTTGGA
+AAATTAAAAAAAAATTTTTTAAAGTAATCAATTTTAATTTTAAAAATTAG
+AAACTTTTCAAATAAAACATTTTTATTTTTTCAAAAATTTTGAATTTCAT
+TTTCAGAATAATCATTAATGAAAATTCAAAAAATTCAAACTACAATACTA
+CGATAACAAAAAAAAATCAGAATGCGTACTACGCAACATATTTGACGCGC
+AAAATATCTCGTAGCGAAAACTACAGTAATCCTTTAAATGACTACTGTGT
+CGATTTACGGGCCTTGTTCTATTTTTGAAATTAATTCATTTTCGAATAGT
+GACAGCCATATTACATTTTTCTTCGCTTTTTTGTATTATTTTCTCTTTTT
+TTTTGCCTAATTTGAACATTCTATCAATCGAGCCCGTAAATCGACACAAG
+CGCTATAGTAGTCATTTAATGAATTACTGTAGTTTTCGCTACGAGATATT
+TTGCGCGTCAAGTATGTTGCGTAGTACGCATTCTCAAAATTTTGTGTTCC
+CGTAATATGGTAGTTTGAATTTTTTTAATTTTCATTAATGATTATTCTGA
+AAATGAAATTCTAAAGTTTTGAATAAATAAAAATGTTAAAAAATTTTTAT
+TTGAAAAGTTCCTCATTTTTTCAAATTAAAATGGATTACTTTTAATTTCC
+AAAATTTGTTTACAAAAAATTCGTTTAAAAAAAAATTAAACTGTTAAATG
+TTAAACTTTTCAAAAAAAAAGTTCAAAATTTTTCTGTAAATTTTTAAAAT
+GATACATGTAATTTAGATTATAATTTAAAAAAAAGACAAACATTTTTTGA
+CGAAAAATATTAAAATTTTGTTAAAAAATGAAAGTTTTTAAAGCCTAAGC
+CTTAGCCTCAGCCTAAGCCCAAGCCAAAGCCCAAGCCTAAGCCTAAGTTT
+GGTACTGCAGTATTTAAAAAAAAAGTTTTTCCCCAAATTTCTTCTGTTTT
+CTTAAAATTCAAAACTGTTATTTGCAAAAAAAAATGTTTTTGCAAAATTT
+GAAATTTATTGAACTGAAAAAAATGTGAATTTTTTAATTGCCTTTGTCGC
+AGCGGCTGGAAACAATTTTTTTTTTGAAATCAATTTTAAGAATAAAAATT
+GATTATCTTGCGTTTTAAACTTGATTAGGGTATTTAAAAATCGATGGACG
+GCGAGTTTTGGTTCAAAAAAATTAAAAATCTCGCCGTCCATCGATTTTTA
+AATACCCTAATCAAGTTTAAAACGCAAAGTAATTAACTTGTATACTCGAA
+ATTTGACGATGATTTCAAAAAAAAATTGTTTCCAGCCGCTGCGACATTGA
+TAAGTTGGTCAAATTTCCGATTTTAACTAATTTTAGGCCATTTTTTGAGC
+CGTCATAACTTTTTTCTGAAAAGTTTTCAAGAAGTTTCATTATAAAATTC
+GGTGTTTTCAGACAATTTTGAGTCTAAGAAGCCAATAAAAAATTCGACTA
+CACCACCTTTAAAGCTCAAAATAACGTCCAAAAATTCAATTTCCAGAACC
+CACGTGCTTCGAACTTTTCGTATTTCCTCATCAACACGTGGCAAAGAGAA
+ACTAATCGATACGGACGATTGTATTGCAAGAATGAATTCGACGTGCGTTC
+TCGCATCGGAATTATTGCCAACTCATCACCAATACATGGACAAAATAATC
+AATGAATACATGAAAAGTGCGAAACAACGATTCCAACAGAATCAGCGAAC
+ACAATCGGATAGTCGGAAACGGATTAGTCGAAGTTTCAGTGCAAGCTCAC
+TTATGCTCACGTGTATCGGTTGTGATTCGGTACGAGACCCACTTTTTGAT
+GGAATTTCGAGAAAAAAGTTGAAAAAACGGAGAATTTGGCACAAGTAGCC
+TCAATATTTGAAAAAAAAAACCGAAAAAATGGATGAGGGGAAGCCAAAAT
+ACCAGAATTTACACCCAATTTTCAAAGTTTTATTGATTTTTTACAAAAAT
+TTTCTCAGTTTTTCAGTAAATTTGCCAGATCTGACCATTTTTTAGGAAAA
+CTGAAAATTTTCGGTGTTTTGCCAGAATAGCAACTTCCTGAAAATTTAGA
+ACTAATTAATTTTTAATTTTTTGGGGGAATCATTTATTTCCTAACAGAAT
+TTGATTTGAATTTCGAAAAAAACCGATTCTAAGCTTAAAAATTGACAAAA
+ATAGCAATGAATGTCAAAAAAATTGCTAATACATAAAAATTGTTTGAAAA
+AATACAAAAATAACAATTTTTATTTAAACTTTAAAAATTTTTCAAATTTT
+AAAAATTGAAAAAATTAAAAAATTTTTAAATTAAAATTAAAACATTTTTT
+GTTAAAATTTGAAAAAAATTCAAAAAAAAAATTTACATTAAATTTTTTTT
+TTCAGGAATTCAAGCCGGCATCTCAAGTGACAAATATCATGTGTGATCAA
+TGTTTTGCTTGGCAAAAAATGAGTGTTCTCACGTCGAATTGCGACCAATT
+TATGGGAAATTCTGGGCCACCGTGCAAAAGTTCAACACTTCCGTCATTTG
+GTAGTAATGATAGTAATCAGAATGATAAGGAAAATATTGTGGAGGTACTT
+AATGTGGTGCCTAAAGATGGAGCCAAGACACTTACCAGGTATGGTTGAAA
+TTTTGAAAAAATTAGAATTTTCAACGAAAACAGAAATTATTTTAAAAATT
+TATTTTTAATTGAAAAATAAAAATTTCTCCCAAAAAATTTTCCCAAAAAA
+AGTGTTTATGTTATTTTTGAAAATTATAATTGAATTGATTTTAAAAATTA
+CGAGAACACAAAATTTGGAGAATGCGTATTGCGCTACATATTTGACGCGC
+AAAATATCTCGTAGCGAAAACTACAGAAATTCTTTAAATGGCTACTGTAG
+CGCGCTAGTGTCGATTTACGGGCTCTATTAACGAAATGAATTAAAATCAT
+TTAGTTATCGAATAATACAAAAATCATTTCATTTCGAAAATCAAGCTCGT
+AAATCGACACAAAAGCTACAGTAGTCCTTTAAAGGATTACTGTAGTTTTC
+GATCCGAGATATTTTGCGCGTAAAATATGTTGCGCAATACGCATTCTTTG
+AATTTTGGCTTCTCGTAATATACGAAGGTTGAAAATTTCAGATTTTTAAC
+ACAAAAACTTATGAAAATAAAATTTATGAAAAGTATAAAAAGTTGAGAAA
+ACAGAAATTTTAATTTTTGCGAAATCTAGATGTCAATTTCTTCACAAAAT
+TTTTCAAAAATCGATTTTTCTTTCGAAAATTTTTTTTTGTAATTATTTTA
+AATCAAAATTTGGCGATTTTCAAAATGTTTATTTTATATTTAATTTCTAA
+AATTAATTATTTTGATTAAAAAATATATAAATTCAATTTTCAGATTGTAA
+AATGAATTTTTTTGAGTTTGCCGTTGAAAAATAGAAAACAAATTATTTTT
+AATAACTGAAATAACTGAAAATGTTGTTTGAAAAATTACATTTTTCCAAA
+AAATCGAACATTTTTGACGCGCAAAAAAATTTGTAAAAAAAAATTTTCAA
+CAGAAAAAACTGTAAAATAGGAAAAAAATTTACCTAAAAAGCGTATGTGC
+CTTTAAAATGTACAGTAACCCCAAAAAAATCGATTTTTTGCAGTATGCGA
+GCTGTGGAGGACGAAAACGGTGTGGTTCACTATTATATGGACGATGAAGT
+AGCGGATTCGTGATTCTATTATACTCATTTCTTTTTTTGAAAATATATTT
+ACTAGAGACCAGTTTTCATTTGATTTTTATCGATTTTTTTTGGATTCCAA
+ATTTTTGTTTTTTTTTTGTTGCTTTTTGTGTGTTTTTTGCCGTCTATCCT
+TCTTTCCTGCCAACGGGATTTTCTCTTCTTTTTTTTTTTTGAAAAACTCA
+ATTTTCCCGCCTAGTATTGCTTTTTTCGAGATTTTTTCTTCCATTTTTCA
+TATCCGCGCCAGCTTTTTCTCTCCCCTCCTTTTTTCACCCATATTTTCGA
+GCTTTTTTCTGTGATTTTTTTTTCACCCCCAAAATTTTTTGTACCAAAAA
+ATTGATGCTTCTTTTTTTTCTCTTTATTTCCAACAAAATGCTTGGCCAAA
+GAAATAAACTCTTTTATAATTTATCATTCAAAAAATTTGAGACCAAATTG
+AAATCCACATCCAGCAACTGCAAAGTGTCATTTGACAATGCACAAATCGC
+ATGGCACGCCCCGTTTTCGTCGATCACCCGGGAACGCGTATTCTGGGACC
+AAATGAGGAGGCGGTGGCGATCGGAGAAAATGAAGTATGGACCACATCTG
+GAAGACACACCTGATTTTACGCGCAAAAATTTAGAAATGTATCGATTTTT
+CGGTCAAAAATCAATATTTATCGATTTTCGGAGGGCACATGGGCTTCTGG
+CCTTCCTCATTGAATATTCGCGCTCCATTTACACTCGCCTGCCGGACAAC
+GCGTGGAAAAGTGTGGTGTACTCCACACGGACAAATACATCAGTTTTACA
+ACTAAAATCGAGCCGTGACGCGACACGCAACGCGCCGTAAATCTACACAA
+AATCTCTCCGACCCAAAATGGCCTAGTTCGGCAAACTCTGCCATTTCGAT
+TTATGAGGGAAGCCAGAAATCCGTGAGGGCAAAGATTGAACAATCTGAGT
+TAAATCGTTTCCATACAAAATTTTTTGAAAATTTTATTCTGAAACTGTCT
+AAAACTCGAAAAGTTATCAATTTTCTGGTTAATTTCTGAGGAAATTCAAA
+AATTGATATTTTCGAAAAAAAAAATCGGAGCCAATACACATCATTTGACG
+CGCAAATGTTGAATTTTCAAATTTACGAGAACCCACGGGATTCTGGCTTC
+CCTCATAAATCGAAATGGCAGAGTTTGCCGAACTAGGCCATTTTGTGTCG
+GAGAGATTTTGTGTAGATTTACGGCGCGTTGTGTGTCACGTCGCGGCTCG
+TTTTCAGTTGTAAAATTGATGTATTTGCCCGTGTGGAGTACACGGCACTT
+TTCCACGCGTTGTCCGGCATTTGTCAATGGAGCGCGAAAATTCAATGAGA
+AAGGCCAGAACCCCGTGAGAATCCTAAAATTCTGAGAATGCGTATTGTGC
+ATCATATCTGACGCGCAAAATATCTCAAAGCGAAAACTAGAGTAATTCAA
+TAAATCACTACTGTAGTGCTTGTGTCGATTTACGGGCTTTCGAAGAAGTT
+ACTTTTTTAGTTTCTTCGTATTATTTTTTTTCATTTTTTGTCTAATTTTA
+ATATTCTATCGATAAATGAATGGGTTTTTATTTATTTTTATTATCGAGCC
+CGTAAATCGACACCAGTGCTACAGTAGTTTTCACTACGAGATATTTTGCG
+CAATATATTTATAAAAGTTGACTAGCGGGCCCTGCGGGCCCGCCAGTTGT
+AGGGGTGTAAGGCGAGTCCCCTTGCCGGGCGTAGGTTCTCGACTTCGCCT
+CGAACCTGTTAGAGGGTTTGTGAAAATTTCAGTAGGTCAATGGGAGTCTT
+CTTGTTTTTTGAGTTCGGTTTGACCAAAAACAGATGCACCCGATGAATCA
+GTTAAAGCTGAGTTTTGATTGATTGAAGTTTGAGGAGGCTTTATATTAGG
+GGAGACGTACCCATATTTTGTATAAAATTGAGTATTTCTATTCGAATCCC
+GATTACTCACAAAAAAACAAAAAAAATTGACACTTGGTAGAATTGAACCA
+ACTACCAAAATTTCTGCAGTCATACGCACTAACCACACGGCCATGCGGGA
+GACACCTCAAACTGGGATGTAGGGAAGAAAATTTTCTGGAGGAAGTCGTC
+TTTCGATTCCGCTTTCTTCAATTATTACTATTTGGGGAAGACGTTCGAAA
+ACCGTTTATCACTGATAAGTCAGCGGAAAACCTAATTTTTGAAAATTTTA
+TCACAGGATTGTACTCATTATTGAATTCCCGAAAAGGAGACGTACAGTTG
+AGGGTTATATCTTGTACACAGACAGATGTATAGAATAAAACAAGTTTTGG
+CCTGAAAATTAAAAAAAATAATATCTCTTGGCAGAGCATTGCTAACGCGA
+CGAAACTTCATCTTCCATTAAATAAAATCAAAAACTATGAATTAAAAATA
+CATTCCGCGAAACTTTAGTGGAAAAAATGTTCAGGGGACCCAGGAAACCA
+CTCCCCCCAGTAAAAAATTTTTGAATTATTTTTTTCTTGAAAAATTTTCC
+CACTGAACTTTTTACAAATTTTATATGTCTCGATGCGTCTTGATGAGACC
+TACACGTCATTTTTTAGAAAACTAAGAAAACTTGAAAACTGACCGAGTTA
+TGATTGAAAAAGTAGATTAGCAAAGATGGGAAAGTGTGCAAAATTTGGCA
+CTTATTCGTCTTGCTCGGCCGACTCATAGTACTTTTTCCAATTCTGAGTT
+AAAAATCGTGTTCAGCGTACTTTTGTACGTGGGATAAAGAAAAAAAATAT
+CAAAAAAGATGAAGTAGAACTTGAGATAAAGACGAAAAACTACTTTTTCG
+GAAAAAAAAATTTTTTGGCAAAATGTCATTTTTTGGCCTTTTGTTTTATC
+ACAACTTTTTTCCATTTGCACTTATGAACTCAAACTTTTTTTCAAAAAAT
+CAGTCTCTCTGAGTAGTATCTTGCACATGAGTTTGAAACAAAACAGAGCA
+AAACCCAAATTTTAATTCAATTAAAACATGCTTTTTTGGGGGTAAAAAGA
+GCAACAAAAAATTTTTTCAAACTGGGGAAAGCCGTCCTGGGCTCAATTTT
+GCTCCGAACTTAGTGCCGTTTTCTGCTCCACTGTGGGGCAAAATATTTCT
+AGTAGGATTTCAAATATTAGAGCATGAAGTCACACGGTTCAGGAGTTGTG
+AATGAAAACGAAGTGGGACATTTTTTCGCAAGCCAAAAAAAACGCGAAAA
+AACGCGAAAAAGGGGCGGAGTCTGTACACTCGGCATTTATTAGAGGCTGC
+TTGGCAGAAAATTATCAATTATGTATATGTATAAGAATTATATTCGAATT
+TCACGCGTAAGTTCCAAATTTAGCAGCATAGCCGCCTGAAGTTCGAAATT
+TAAAATAAAAAAACCGAAAAGTACCTGACAGCCAACGTGGCAACAAATGG
+AATCTCATCGACAAGTCCTTCAGAATTGAATACTGCAGCATTTGACGTAT
+GATAAATGACTGCCACGAATTGATTTTCAAATAATATTTTATTGATTGAC
+GTGGCAGTTTGGTGGCTGAGCGGTTTGTAGTCCAATGTTGGTAGAGTTAA
+TAGGTAAAGACCACCCGTCTCGGTTGCCACACACGCTTCTTCGCCGCTTC
+TGGAAAATTTGGTTTTGAATTTCTAGGCCATTGGGTTAGGCTTCGTTTTT
+GAAATGGGTTAGAAATGTAGAAAATGGAAATTCTAGGCCATCAATTTTCC
+TTTTGCATGTGTGTAGGAAATTGGCTAACATTCTAGAAAATCGATAATTT
+TATAGAAAGTGAAATTTTCGCAAAATCAATAATTCGATAAAAATCGATAA
+ACTTTGATAGAATTTTGTTCATCAAAAACCGATAATGTCCGAAAAATTTC
+AGAAAATTAGATTTTTTTAACAGTCCGTTCATTTCGTGGCCTAGAAACTT
+ATTTCTAGGCCATGGAAGAGTTTTTCCAAGATTCACGGCCACACGTACAC
+TTGCATGCTAACAATTGCGACAGGCTTATTAGAAGTCGAAGATCTTCGAA
+TTTTTCGCGACAGATCCGACACTGTGAGCTTTGTCCCGCCGAGTTTTTCG
+AGTCCTGATGTTCCGATTTGCCATAAAATTATATTACCATCGTCGGAGCC
+TGATAAGAGCCCGTGACGACACATTTCTAGGCAAGTTACTGCTCCGTCGG
+TTATCTGGAATAGAGAACATTTGGAACTTGTCGATTTTCAGAAACATTTT
+ACTGTACTTTTTTATGGGCAAAACATTGTTTTTTTTAATTAAACAAAACT
+ACTGATAATTGTAAAAAGATCAATTTTTTAGTGTTTGAAGATCATTTTTG
+AGTTCTCTAGCTACAAAATAAACAATTTTAGAGGAGTTGCAAAATTGTGA
+ATTTTAAAAATAAATTGCACAATTTTGCCACTTTTTAATGGTTTTTGATG
+GATTAAACCTAGATTTTCTGAATTCAGCATACATGAATTACCGCTTTTTG
+ACAAAATTAGACAACTTTTTATTTTTGTCCAATTTTTTTCAGCCATCTAA
+TGACTGTCCTTTTTTTTGGGCAAAAAAATAAATTTCCTAAAAGCGTTCGA
+AACTACTATATTTTGAAATATTTTGAAATAGGACATTTTTTTAGGGCTCG
+GAGATCAATTTTAAGTTCTCTAGCTACAAAATGCGGAAAAAAATGTAAAA
+AAGTTTGGTACTTGTGTATTATACCCCCGCCATTTTAAAAATTAATAAAA
+TTTCCATCAATTTATTTATTTAAATTAAACGTGATACCATTTTTCCTTGT
+TAGGCTTAGGAATGGTTTTTTCCTAAGCCTGAAATTCCACACGTTTTTAT
+TTAATGAGTTAAAAAATTAACTTTTAAAATGGCGGGGGTGTAATACACAA
+GTACCAAAAGTTTCTAGGCCCCATTTGCTGGGCCACAATTTATAGGCTAC
+AGTTTCTAGGACACATTTTCCTGGGAACATTTTCTAGGCCACATTTTTTA
+GGCCACATTTTCTTAGCCAAAAATGTACTCACAAACTTAGCAACGTGGCA
+ACAATTTCAAAAAAAACCTCATACCTTCTTCTCGAAAATTATTTTATCTT
+TCGAACACATTGAGATATTTCCAGAAACGTCGCCGAGAATAAATTGGGTC
+GATGAGTAGAAAACTGCAGAAATTGCACAAACCGGTAGAGGAATCGAGAA
+GCTCTGAAATTATTCTTCATTAATTTTTTCATGCAATTTTAATCTCGGAC
+CAATCAGCGTTTTGCCACGTCTTTTTTTTTTCGAACCAATCAGAGGAGTG
+GGCGTGGCTAGATGCTGATTGGTCAGTTTCAAATTTTTTACAAAATATGA
+CCTACCGTAGAAGAAGAGCACAAAAGTGCTCTCGCCTGATGGGAACAGAA
+AGTTTCATGAGAGATACCGCCGAACAGAATTAACGTTTTTCGTGAAGAGC
+TTGAAATCATTAGAATGATATTTTCATTTCGGGTCTGAAATAATTCAATT
+TTAAAGGTACACGCCACCACCGTATCCTACTTCCACATGGTACTTCTGCA
+CAGTTTCCAGCGCAACTTTATCGAATTTGTGAAATTCCAAAAGCCTGTCG
+TAGTTCACCTTAGAATCGTCACGCACGAAATCGTAAAGGAGGTTCAGAAC
+CTAAAAGTTTGAAAAATATGTCCTAGGAAATCAAACTGTGAATTTCTAGG
+CCACATGATGGAAATTCGTATGAAAATTGCGACGAGCCCTAACATGTGGC
+CTATTAATTGTGGCCTAGAATCTGCTGCCTACAAGTTGTGGCCTAGAAAA
+AATGTTTCCTAGAAATTGTGACCATGGCCTAGAAATTTTGGCCTAAAACA
+TCCGACATAGAAATTGTATGGCCTAGAAAGTGTGGGGGCAAAAGTTTTTA
+ATTTTCAATTCGGTTTTTTTTTTCACAAAATGGAGAATTTTTTGATTTTT
+ATGTCTGAAATTGAATGGGAAACGTGGAAATATTGCTAATAACCAACCTC
+TTTGCTAATTGTAATATCCTTTTTCACATTCTCGCCGACACCATTATCCA
+CAGAATCCGTCTGAACTTCTTTATTTTCTTGAAAATTTGCCACGCATTCC
+ACGTCTTTTTTATTTGTCTCTATCGTCTGCGTCTCCGACGTCTTATACAC
+TATTTCTCCCTGAAGGCGGATAGGTTTTCTCCACGTGAACTGGAATAGTG
+TGACGTCTTCCATTATTAGCTGAAAATTTGAGTTAAAACTGCTCTATCAC
+ACTAAACACGACGACACTCGTGGCCGCGGAAATTAGAAAACTCGGCCACG
+TAACTTGGTTAAATTAATGAAAATATTATAAAAAACTTTCGAAAATTTGA
+AACATTTTAACTTTTTTTAAAAAAAAACACATGCAAATGTTCCTAAACTG
+GCTAAATAAACAACGCACATCCCCGGCGGAGCTCTGGTTTTCCATGGCAA
+CCGAGAATGCGTGCGGGCCAACGGGGAGAATGTGGAGTACGTAGAGACGC
+AGACAGTTGTATAAAAGGGGCGGCAACTTGAAAAAATAAATTTCTAGAGA
+TTAATCCGTGCAAAGTTGTTTTTAATTACCGATGACCGAGTATGTGATTT
+TTCTAGGCCACGGAACCAAATTACGGCGGAGTTCCGTTGAAAATATCGCT
+TAATTGTTTTGTTTTTTCTACCAAATTAACTGACTGAAAATCCAGTTTTT
+TTTTTCTGAAATTAGGTTCTTTCAAAAATCACCTGAGTGTTCCTTGATTT
+GTTTTCGTAACTTTTTTCTCTCCAACTATTACACTACGGGTGTTTTGACA
+ACACAATGGAAAACATGTCTGTTCAGTTTAAAGACTGACAAGAGTCTCGT
+AGTCTCTCGCGGACTAGCTTACGGCCCTTGTGGTCTAGAATATTGAAAAA
+CTTAGTTTCAGTATTGTGGCCGCGAAATTTGAAAACTCGGCCATCGATTT
+TTTTTCCCACACCATGGGGCAATATTCACTAGACCATTCATTGTAACAAA
+TATTTCAAAACTAAGAATTAAAAAAACTCCTACGCAATTTCCCCAGTCAC
+TTGGCGGCTCTCACGCTCCCTATTTCAGATGTTAACCTCATTTGAATAAA
+TTGCTTCTCCCATGTGTTTTTGGATGGGATACTCCATCTTTTTCAACCAA
+TTTTTTCTCCTTACTTTTGTTTTTAACGGCTTTTTTTCATATTTCTGATT
+GAGAATAGGTCAAGTGATGACGTAATAGAGCGCGTGGAAGAGGAGTGACG
+TCACACGTGGCCTAGGAATCTCTGCGACCACCACATGAAAAACGTTTTAT
+TTTCTAGGCATCCCTACCTACCCGTGTTTTGTCTCTATTTTGACAATTTT
+TTGCAAGTAAATTCCCGGCTGAAACAAGGTCACCGCAACACAAAATAGGT
+GAAGGGATGATCTCTTTTTTTCCAGAGTCAGTCAACATACATAAATTATG
+TGTGTCTCTTCCATTTTCCTGTCGTCAATTTGTTCACTATTCGCTTCACT
+AATTCCTGCTTTGCATTTTAATGTCCGTGCCCTCTCACTGGAACTGACAT
+TTCACACAATGTTTTTTTCGGTGGAAAAAAGTTTTCTAGATTTTGATATT
+TGCTGGAAATTTGGAAAATTTAGCGACTTGACCGTGCAAAAATTTTGGTG
+GCCGAGTTTTCTCTTTGCGCGGCCACGTTGTAATAGTTGCCAGGTGTCGC
+AAGTTTTTAAAATGACCGAGTTTTCTCTATTCACGACCAGATCTCTCATT
+ATAGCCGACTTCCGACTTGCGTAAAAGTGCGACGTGGCCGAGAAAAATTT
+CAGTGGCCGAGTTTTCACGCGAAATCACATTTTTTTAGTTTTTTGGTACG
+TGGCCTAGTTTTTTAAAACCATTGTTTATCTCCACCCAATCTAAAAAAAT
+TTCTGCGGATTTTTAAACCATGGCCGTAAAAAAAAGCCACTCTCATATAT
+TTTTTCGACACCTTTCGGTTTTAGAAATATATTTTTAAAAATAAAATAAA
+TGGCTTTGAAATCCAAATAGAAATAATTTTCCAAAAAAAGTGGAAAATTT
+TCTAGGCCACTTGAAATTTTTTCCGAGATCTTTTTTGGGAAAGGAATTTG
+TGGCCTAAAAAACAAAAACTCGGCCACTATTTTTTGACCATTTTTTCCAT
+GTGACGTCACTTGTGACTTACAATTCCTTTTCTCAATTTCTTATGAGAAA
+TCGCTTTTTTTAAGACTTTTTGTGATTTTGTTGCATTTTCTCCCAGTCGG
+AGATTACGCCACGTGGAAATAGTAAACTCGGCCACACTCTTATAATTTTT
+TGGCGTCTTTTGGGAAAAGTAACAAGTTCAAACAATGTAAATTACATAGC
+CTAGACTTAGCTGACCAAGGCTTGTTTGAAATATTTTTGTGGCCTAGAAA
+AATAAATATTCGGCCATTACTTTTTCTTCTCATTTTTGTCAGAAGACGTC
+ACTGAAAACCTAGAAATCTCTCTTCCAGGGCTGCAAATGAGTATATCCTC
+CATACCTTCGTCACCGTCAATATCGGGATCTTCCACGTCATCGACCGCGC
+CGAACATTTCATTTTGCTATACATGGACCACTAAGGTAAGCGGCCTAGAA
+AAATAGAAAGTTCGGCCAGCTCTTAAAAAATCGATTAATGATAATTTTCA
+GTTAAAAACGCGAAAAACTGCGGACGGCGAGGCGACGATTTTATCGATTT
+CTCCGAAATTCGCGACAGTCCACCAACTTATTTCGTTTCAATGGAATATT
+CGAATTCATGCCACTTCTGAAATGGTAAGGCTTGTTTTTTTTTGAGGTAG
+GCAGGCACGAAAGCGTCTGCTTGCTTTTCGAAAACACGTGGCCGCGGACT
+GAAAAACTCGGCCACCAAAAATCTGAAACTGTGAGTCGCCCTGACAGAAT
+TTTTTATTTTCTCGGCCAAACAGCAAAAGCCGACAAGTGAAGTTAAAAAG
+GGAGGAGCATTTTTTTAAATAAAAAACTAGACTCCTAATGACCTCAAAAA
+TATCATATTTTTAAATGTAAGAGTCGGCCACGTCCGCGGTCGATTTACAC
+AGTGTCGCGGCTCGGTTTTCATTAATTGAGCACTGAGAAGTTTCACTTCT
+CCAATTTCAATTTTCAGAACGAAGAAGACGAAGAAGTGGACTACGTGGCA
+GTTGACCTTTACCTGGTAGATGGTCCTGTAAATGAGGTGAACGTTATGGC
+CGAGGTGGGGGCTCTAGAGAAAACATCCACAGCAACGTTGGGAAGCCTTC
+CCGCAGGTCAGAAAGAAGCAAAGACTATAAAAATGCAAAAGGGCTCTGGT
+TGTGAGATAACGGATGCAGATCGAGAATGTGTGTCGAAGTATTTGAAAGA
+GAACGTGGAGAATATCATCAAAATCTCCATAATTATAAATATGGAGACAC
+GACTTTTCGAACCATCAACCTATTTGGATGCAATATCTCCAACTCCTCGA
+GCATCATTTCTAACGGCAAATTACAATGCGAGAGTTAACAGTAAGGTATG
+GAAAAGGCGATCACGGAAAAGGAATGGAAGAATCGAGCGAAGAGTGTTAA
+GTGATAAAGAGAAGACGAAGTATGAGAGTAAAGTACAAATGATATTGGAT
+GAGGAACGGGAGAAGCTGTGTGATAAACGAGAGATGTTGAAGGAGGATGA
+TGGTGGATCGAGAAGAGCTTCGTTGATTTCTCAGTTCAGGGAGAATCAAC
+ATGAATCTGTGTTGGATGATCATATGTTCAAGAGGGTAAGGTTTTTATTT
+TTAATGCCTAAAACTTTGAGATTGAGGCAGTTCAATAGGCTATATACATA
+TAAGTGTGGACCCAACAAGTTTGTTACATGAAGTATTTTTTCCAGATCCT
+CGTTAGCTGCTGTGAATCTTGCGAGCAACGTCGTCTATCGTTCATGTGTG
+ACAGTCGAACCGAGGATGATTCTGAAGGGGAAGATTGTGAAGACAATGAA
+GAAGATGATGGAGAAGGTGGCTCCGATGATGAGGAAGACGATGGAGAGGA
+GCCTCATTTTGAATGTGATAAGAGTGATAAGGAGCATGTCCACGATGTAG
+GTCTCCTTTAAAATATCGTCCATAAAAGCTTAATTTTTTAGATGCTAGCA
+AATCTATACTTCAACAAAGTAGTCCTTCCCGAAATGGAATATGTCGAGGA
+TTTTGTGGATTTCCTGATTGATGCGGAGCTCAATGACTTGCCAGTTCTCA
+AAAGAGCTTGTGAGAGGTATTTGTGCAGTGAGCTGAATTCGGTAGGCTTC
+TGTTCAAAAAAATATAAAAATCTAATCGAAATATTTTCTAGAAAAAAGAC
+ATTGGAACTTGTCTCCTGTTGGATTTGCTTTTCAACTCGATTGTATTCAA
+CTTGCCTGTTATGAAGTCGATGACCTTGACGGAGTTGGCGAATCGAACGC
+ACGAGTTTGTGGATGCTGACACACTTTTGGATCAGGAAGAGTTTAAGTGA
+GTAGGGTGTGCGGCAAATTTGCCGAATTTGCCGAGCACGGCAAATTTCAA
+AAAAGTAGATTTGCCGAATTAGCCGAGCTCGGCAAATTTCGAAAAACTTA
+TTCATAAACCAGCAGTGTGTAAAGAATTCAGTAGTTTTGGTGCTCCAAAA
+ACATTAAAAAATATCAAATTTTTTCGAGTTTGTCAAGCACGGCAAATTTG
+CCGAATTTGTCGTGTTCGGCAAATATTGGAAAAATAGATTTGCCGAATTT
+GCCGAGTTCGGCAAATTTTGAGATTTGCCGCACACCCCTGGTGTGCACCG
+TTAAAAATTCTTTTTTTCCAAAAATCTAAAACTTGAGGTTAATAATGTGA
+CCGAAAAACTGAAAAAAAAAAGAATTTGCCGCTGCAAAACCATAATCCGC
+CAAAAGTTTTCTTTGTTTTTTTTTCGAATTGCAGGGTTTCCGAATCTGTC
+AAAATTGGAAACACGACAGTTTGCCGAAAAAATTTAATTTTTGAGTGAAC
+TGTTGATGCGAAATTCATTAAATACGATTTCAAAAAGCTCGGTCACGTAT
+TTGTAATTTTAGAGTGGGATTAGCTATTTAAAAATTACATTTGTAATTTC
+CAGAAACCTGGATAAAAGAATGCGAACGCTTGCCGATCGGAATCTCGTGG
+AGCTCATCGAGCAATGTGTTACGTTTCGTGACCAAAAAGCAAGAGTTCGC
+GTTTTGCCGACCGCCGAATCATTTGATATTTCGTTCGACTTAACTAATCA
+ATAATATTATCGTGTTACTTTTTTCCTCTGTTTTCTTTCTCATTTTTAAA
+AATGAATGCTTTTTTCTTTTTTTTTACCCGATTTTCCACACGACTAACTC
+CAAAATCAGCCGCGCCTTTTTGTCTTTTATCCCTGCTTTTCCACACATTT
+ATCAAATAAAGAGTGCAACGAAGTGCAAAATGGGAAGTAGTAGTGCTGCA
+ATCTCATTTAGAGTACACTTTTGGAGCTCTTTTCTCCAGATATATTATAT
+GCTGTAGATGGAAACTTTTCCAGTTTATATATAATATTTTTCATTTTCCA
+TATTGCCCTTCACTGCTCATCATCCAATGGGGTGCATCTAATTACGGCAA
+AGCTTCGCGGATGGGGCGAGTAATGAGCAAAAGAGCACAAGGATGGGGCT
+CTTTTGTTCCTCATTTTCATTGCTTTTTGATTTCATTTCCTTTTCAACAT
+GTTTCCATTTTCGAAATTAATCGGCTTTTCTGACCCAGGACTCACGGGAG
+ATGAAAATTAATCTTTAAGAATTGTGCTTTGAAAAACAATATCATACACT
+TTTCAAACTTCATTTCTCCGTTGTTCCCAGTAAATTCCAAGCTGTCATCC
+ATCAACTCTCTGATAAAAAATAATCATTTGGTCCGTCCGTCGCGAAAATG
+AAGTGAAAAAAGTTAATCCCGGCATGTTGAAATACACATTTCGTCGCGTG
+GAGTATAGTTATGCTTCGATTTCTCAAGAGGATTCTTCTTTCCCCCTTTT
+CATATTTTTTCGGGCAAAGAAGAAATCTCTGTCACCCCCCGACTAAAAAA
+CGCTAAAAATTCAGCGTTCATTGTTCGGTTTTCCGTTTCAAAAAGAAAAA
+AGTGTGTCAAAAACTCAAAAAGTCACCGCCTAAAGTTAGTTAGCACCTTT
+TTCCATTGTGAAGATTTTCTTTCCTTCAATACAACTACTACAGTTTGTTT
+CCTGTGTGTCGTCCTATTGTTGTGGGTGTAATTGTTCGATAGAGCGCGCT
+TTACAAAATCTCTCGAATTAATTGAAAGTAGTGTGTTGTAGAGACCTTGA
+CTCCTTTGTCAACACTGTAATTAGGAAGGAGTACACCGCCGGGCGGGTGA
+GAACAGTTATTATAACGATAGTGGTTTGTTATTGTTTGTTATTAATAGGT
+TAGTTGTCTACTTTAAACGTTTTTTGTTTGAAAAATTTCTGTTAATTAAA
+AAATACATAATTTATAAAAATGATGAGTTTTTTTTTCAAATTTCTCAAAA
+ACCGAACCCATGGGGTTTTTTGAGAAAAAATAAGAAAATTTTTCTAGTTA
+TTCAAAAAATCTATACATTTTAATATCTGTAAATTGTAAATTTGGAAGAC
+AAAATTTTGACAATGCGTATTGAATTTGAGTTTATTTAACTTAAAGAAGA
+GAAATAGACAAATAAATAATTATATATATTGCGCAACATATTTGAATAAT
+ACATTTATTTTTCGTAATATTTATTTTGAAAAATGATTGAAAATAAAACT
+CGAAGAAAACTATATTTAAAAATGTCGGTGCTTTTTTTACATTTTTTAAA
+CGAAAAAAAATGCGAAAAAAACCAATTTTCCGAGTTTTTTCTTCAAAATA
+TTCGTCCCTGTTCATGAAAAATGTTCTCACTTATGTAAGTAGTTGTCACG
+CAATGCAGTTGTTGACCAAAAATTATTTTCCGAGTAAACCCTATAATTTC
+CAAATTCTCTTCTTCTGAAATTTTGAACTTTCCATCGGGAAAATGTCATT
+TCAACTCGAATTCACACTAATTATACATCTGTATAATTATTTAGATTCGT
+ACTTTTTCCTCCTTTTGAAAAAGTGCACAGACACCGCCGTTATCTTTACA
+ACCGTCTGGCAGGACCGGTGTTGTAGGCTTTAAATAAATATTTTTCCATA
+AATTTCTTAATTTTTAGCTGAAACGATTTTCCAACAAAAAAAAACGCACA
+TTTAAAATGGTTACCGTATTTCTTCTATCAATATGGCTGCAATACTATTT
+TTCGATGGTCTTCCCGCTTGCAATACTAATAGGGAGTGCAAGACTATTAG
+GGAGTGCAATACTAATTTTCAGAACATTTTTCTGACTGTGAGCTTACTAT
+TTTTTTTTCTGAAAAAACTCGAACCTTGTGTGAAAATTCAGAAAATTTGA
+TTGTAATTGCAACAAAAAGGTGTAATTACTTCAATTTCATAGAAATTTTT
+CCAAAAATTGTTGCACAGTAGGCAAAAAATGTTGTTAAAATCTCAAAATT
+AGTGAGGTGATTTTGTACCAAAAAAAAAGTAGACGCAAGACTATTAGGGA
+GTGCAACACTAATTGGGAGTGCAATACTAATTTTCGGAGGGTGTTCAAGG
+AGCAATACTAATAGGGAGTGCAAGTCTAATAGGGAGGTCATATTAATAGA
+AGAAATACGGTAAATTTTATATTTTTCGGTGCATTTTCATTTTAAAAACA
+ATTTGTTTGAAAATAATTATTTTTAAAAATCGTTTTCTTCAAATTTTTTG
+TAATTATAAGAAACCAAAAAACCTTTATTTAATTTTCAACAAGTGTATTT
+TCTAATTAAAACAATTATGAAAATTCACAATAAAAGTTCAGGACTGAATC
+CAAAAAAACTTTTATTTCAAAAACGAAACACCTTGTTTGCCAAAAACCTG
+GAAAAGCCTGGAAACCTGGAAAATCGAATAACATCAAATTTTGCAAATTT
+TAAGCGTTTTCTCGAAAAAGTTGACCTGAAAAAATAGGATTTTTCAGTTT
+ATTTTATAAAAAAGCGAAAAAAAGCAAATTTTTTGAGAAAAAAATTGCCT
+AAATTTTCGAAAAATCATTTTCAAAACTATTCACGATTAAAATTCGTTTA
+TCCATTTCTCCTTCAATTCTTCCAGATTCGAATGAAAACTTGCTCAGAAA
+AAATGCTAAATTTGCTCTTTTTCGTATCCACTACTACTGCTACTACTAGT
+AGAAGTTCTTCATTCGGTGGCCGGACTACTTTGAATCAAATCACATTTGT
+CGGGAAGAAGGAGGTCGTGCCTTTGCACTTCTGGTCACTCCAGAAATTGA
+AGAAATTGAGCAGCTCGAGTTTTGGAGTATTCCAGGCAACTCGGTCGTTT
+TTGAAAACCTATTCTATGAAAACTGCAAACTATGTGGCTTCATCTGGTCT
+GGCTGGAATTTTTTGTTTCAAATTTTGACCCAGTACCTTGAGAATCAACC
+AGTTTTCCACGTATGCTAAAATCCGAAAAAGTGACTCACACGAGAAAGTT
+TCAATTTCCGTGATGACGTTCGCCTGGCTCTTCAGCTCATTCTTTTGTCT
+CCAGAGCTCTGGGGAGCTGCAAATGAGTTGAGAGCAAGCACATTGCGTGA
+GCAAGATAGCTCCAAAAGATATGAAGAGAGCAGGCGGGAGATGAAATTGG
+ACGATGAAAAGTCGCCAGAAGCATAATTTTGGTGCGGCGACACCCGAATA
+ATGAGACATTTACGACTTTTTGGAACATCTTCTACGGCCAGAATGTTTCG
+TAACATTTTGGTAATTTGAGTTGTAGTTTTGAGGGGCTTTTTTCGATTTT
+TAAATTTGTATTGACTCTTATTCGCAAAAAAAGAGAACTGCTATAGCACG
+TGTAGTCAAAATGTCTTTTTGATCTTCAAAAAATGCGGGAGTTAAGACGC
+AGACATCTCATCTGATTCGCATGGCTAAGAGCGTGCTGACGTCACAATTT
+TCTGGAAAAATATTCCCGCATTTTTTGTAGATCAGGCTATGATGTGTGTG
+TTCAATGAGACAGCCTGACACGACGTGATGTAGTTCACATTTTTCGGCAG
+TTTTTTTCCTGAAAAATGTGGATTTTCGTTTTTTCTTAAGTTGTCAAATT
+ATCGAAAGCTACTAAGCTTGAGTAACTTAGGAAAAGTAGGATTTTAAATT
+GTTTTCACGGGCCTCGCAACGAAAGATCTCACTACTATCACCAGAAATCC
+AAAAAAACGAAAATATTTGTCGTGCCGAGCCCAGGCTCCGTATTTTTGAA
+GCGAAATTCCTAAACTCCCTAACCGCTGAAAATTTCTGAGTTGATTTTCC
+ATCACCTTCTATATACAGTCTTTCGACCCGAAAACGATTTGAATTCGGCT
+TTCTCCTCAAATCCTCTGTATTGCATCCTCTTTCTTAGTTGATTTATTTG
+TAGCGGATTCTTCCCCTTCCCATCCGTGGCGTTATTGTTCGGTTACGATA
+CGCTTCTTGTGAAGGTTATATGCAAACGACTACTTGCCATTCGATTCTTT
+CTCCAAAAACGGGTTATTCCATTTCCTTCAACTAAGGAGCTGTTTTTTTC
+TTGGTTTTTTGTAGAAAACCTACATTCAAAGTCGAAGTAGTGAAAGTCAA
+AAATTACCAAATTTCGCAATTTAATTTTTAATAAAATGTCGCCCGAATTA
+ACGATAAGTTAATAAGAACAAAATTCAGTTAGTCCGAGAGTCGTGATTTG
+CCGATTTAGAACAGCATTTAGCTGAAAAAAACGATTTTTTTCCAAAGTTT
+GAACTGCCACTACATTTTTCTCAAGTATTGAGAGTTTTGAATTTCCATCA
+TTTAGTTGTAACCACACTTTTCTTCCGATTCCCATAGCAAGCGAAAGTTG
+TCTTGTTTCCGAATATCTGACCTAACTTGGTTTTTTTACGACTGATGCCG
+AATTTTGAAAAGTTTATTAGAAACTTTCCACGCTCTCCCCTTTCCAACCT
+CGCAAACCCTTTTGTCTGTAGTTGGGATCTGTTGCTTTTTTGGGCAATTT
+TTTGCCAGCTTGATCTACATATCATTGCTTGATCTACATATCTTGAGCAA
+AATTCCAAAAAGTACGTTTTCTTGTAGATTAATTTGTGGGTTTTTTTTGA
+GAGTTTTGAGCTAAAACTTGCATGGCATATTTTTTTCACTGTTTTAAATC
+ATTTACAAATTATTTTTTCCTCTTTTTAGAAAAAAAAAATGTTTGTTAAA
+ATTTTGGAAAAATTTCAAAAAGGTGTTTTATCCACTTCCAAAACGTCATA
+ACTTTGCTGAAACTGGACCGGGGCAGCTAAATTTTTCGGAGTGATCATTA
+TTTTCACTCTTTTATCGAAAAATTACTATGGCATGCCAAGCCCGGGGACC
+CATTTTTTCACTTCCCTTGTAAGCCGAAGCCTTAGTCTAAGTCTAAGCCT
+ACGACTGAGCATAAGCCTCAGCCTAAGCCTAAGCGTAAGCCTCAGCCTAA
+GCCGAAGCCTAAGAATAACGGGAAACTTTTTTTGTTGCTTTTTTTTGTTT
+TTTTTCAAATGCCGAAAAATAATTGCGGCATTTGAATTATGACTTTGTTG
+TTCCTAGAGATTCTGGTTTTCAAAATAGGCAAAAATGCCATGAACCTTAA
+CGATGTTCTTTCTCCCCGCCCTTTGAACACTCTGAAGTTTCCCGCCATGT
+CAACCTTTTTTGATCGTTCGGCACGATAACGTTCTGAGTGCCGCGGTGCC
+CGTTAATTTCCATCGAATCGTTAGGTTTTCTCCTTCGATTCCTAACGATC
+AAGCCATAATTTATCCGCAAAATGGGATTTTCTCCCTTTTGTGATGATGA
+TGATGATGGCCTCCCTCTTCTCTGCGATGACAGTCGAGTGATGAATGTCT
+TCCTTCACACTTGTCCGTTTATCATTTATCACTCTGTGCTGAAAACCGGT
+CTCTCTCTTCCCCTGACCTCTTCGGCTTTGTGAAACAGTGAAAGAGAAAC
+GGAAAACAGGCGGTGTCAGATGGTTGACACGTTGATGTCGTAATCCATTT
+AGTATTAATGCTACTATGTACGCCATTTGCTATATATGCCCATATTTTCA
+ATGGCTTTGAGCACAAGCTTTCAGAATTGGCAATCAATTTCTAAAATTTT
+AAAATTTTGAAAACCAATATATGGGTGGAGCCTATTTCTTAACTGTTCCG
+TAGTTACCGAAAAAGTCGGAAAGCGCCGATTATCTAATACTTTCGAATTC
+GGCAAAACTGAAATTTCTTCAGATTTTTATGATTTTGAGAGAAAAAATTA
+TATTTCTTTGCCAAAAAACATGTATTACTTAAAATTTGTTTGTTTTATTA
+TTTGAGCTCAATAACTATCAAATTGACAAACAATTCATTGGCAAAAATGC
+CGAATATCGTAAATTTGAAAAAATCGGCAATTCCCGAATTGCTGCACACA
+TCTTGGTTTTTTGAGCTAATTAATTGAATTTTTAAGAACTTTTATTTTGG
+TAATCTAAATTTTAGTTACTGAATTCATTGCGAAAAAAATTTCTTCAGAA
+TAGGGCTTCCATGTAGGCGTCAAAAAGCTTGCCAAACCTTAAGACGACCT
+CCGCCTGCCTACCTCAATCTATGTGCTGAAACATATGCGAACTTTTTTTG
+CAATTCTTGATTTGGTTTTCATCAAATTGATAGAAATGAGAAAATTTAAA
+ATTGAAAATTTACGCACAAGTACAAAAAAGGATTCAGGCAGGCGTCAGGC
+CGTGAAACCCCGCCTGCTTACCATGGAAGCCCTACTGCAGAAAATGAGAA
+ATCTGATGTTCAAAAAAAAAAAGAAACCAGCCGTGTTTTTCCTTGAAATT
+CGAAAAGTTCCCCGATTTTCCCCTCATTTCCGGACCGTTTGTTCCCATGG
+TGGACCGGTATTTTCACCACTCCGTCAAAGGCGATTATCGGGTCTGTCTG
+TCGTCGACGACCCATCACACCAAATCGGTTGAATTGTCGCACCCCTTTTT
+TAATCGGCAATATATTTACTTTTTATTTGTAACTAAGTAGTAAACAGTAA
+TAGTTTTTGCAAGAATATGCATAACACCTTATTTCACTTGGTAAAGTAAT
+TGAACTGTTGTAATTGAGCTGAACATGATTCACCTACGAAAAAATGCCTG
+TGACCTAGGGCTTGCATGTATGCGTTAAAATGGCTGCCTGCCTGACCTGA
+AGGCAGCCTCCGCCTGCCTTTTGCCGGTTTATGCTAAAAACACGGTTTAT
+GCTACGTGAAATTATTTTTTCATTTTTAATTTGATTTTCAACTTTTGAAA
+TTTGAAAATTCACGTCAAAATGCAGAAAAGAAGGTGAGGCAGGCAGGTTT
+CAGGCAGGCGTCAGGCCCTGAATCGGCGCCTGCCTATCATGAAAACCCTA
+CTCTGAACTCGATTTCGCCCTCCAAACATCAATTTCCGTCATTCTCCTTC
+CGTCCTTTTTACCCACTTTTTTAATGAATTTGAAATGAGTAGTCGAGGGA
+AATTTAGTGAACCTACTAGAAGTCGCCACGGTTTTCAGCAGCAAATTTTT
+TAATTTCGTAGAAATATGTGCTTCTGTGTTAAAATTAATAATAGCTAAAC
+TATTGGATAATGTACTTTAAGACGTGCAATGTCACTCCATATTTTATAAA
+ATGTTGAAAATTTTGGAAGGGATCGAGGAAGTTTTGATACTTTTTAGAAA
+TCGAAAATTTTCAATTTCCGATTCCCTTCAACATTATATACCTCAACAGT
+TTAATAAGATACAAAAAATCTTCAGAGAGTCATCTGTTCGCACACAGTTT
+TACCCCTATCAAATTACAGATGTGTTGCCTTGCACATCTGTGAGAACTTC
+ACACTATTCTGCTACAACAGATTTTCGGAACAGAAGGTGTGATGTTTCTA
+CCTGACTATGAAGATTCACGTGGGCGGCAATCCAAATTTTTTGAAATTTG
+GAGATTTTCGAGTTATCCATAAAAGATTCCGTTAAAGAGAGATCACAATT
+TTTTTTGTAGATTGACAAGAAAATTACCCCAACAATACTCAAAACAATTG
+TAATTACAATTGAATTATTACTTTTCAATTCTTAATTTTTTAAGTGCTGA
+AACTTTTCTATTGACGTTAACCCCTGCAAAAATGCAAAATTGATCAACAT
+CTAGTAAATCTACTAACAAGGGAAGTCTTTGAGGGGGTCCGTAGATTTGG
+GGTTTTCATGCTAAAATTCCTACAGAAGAGTGTTAGTTATGATCTCTCCA
+AACATTTTTGCGCATTTTTAAAGTGATTTTATTCTTATTCGGGAACCTAG
+AATCATTGTCCGCACTTTTTGGAAATTTTTATTTTTTTCATTTTTGCTCA
+AAATTTCTTGATCAACTCCAAGCAAAAAAATCAAAGTTTTTCAACAAACA
+TTTTGTTAGTTGATCATTTTTCAAAATAATTTATCTCAACGAAGTTATGC
+AACTTCAAAGTTGGTTAAATATTTTGCACAAAGTTCGTGAGATGTAGATC
+ATTTCGACGGTTTACTTGCGAATAGAGAGTTAAAACTTGTGTAATGTACG
+TTTCATACATTTCTGAACAATAAAATAGCAATTTCATACATTTTTACAAA
+AATAAAAAATTTCCTATTTTTGCTTGGAGTTGATCAAGAAATTTTGAGAA
+AAAAATGAAAAAAATAAAAATTTCCAAAAAGTGCGGACAATGATTCTAGG
+TTCCCGAATAAGAATAAAATCACTTTAAAAATGCGCAAAAATGTTTGAAT
+GAGTTGTTTAAAACTTTATTCAACTTACAAAAATATTTCAAAAATAGAAG
+GAATCGAACCAAACCTTAAATATTATCAGACGCGCGCACTCCCAACTCGG
+CCACCGAGGACAATTTTCAACTCAATGTGGTGGGTGTCACATTTTCGGTG
+GTCACGCAAGCTGAGATTTGCGTGGACTGCATGGTAAGACAGTGGATTTC
+AATGGTGTTTTTAACTTTCAAAACGTCATAACTTTGCTGAAACTTGACCG
+GGGCAGCTAAATTTTTTGGAGAGATCATAACTAACACTCTTCTGTAGGAA
+TTTTAGCATGAGAACCCCAAATTTACGGACCCCCTCAAAGACTTCCCTTG
+TAAGTCAAACAAAAATTCTGTATTTTTCAGAGTACTATACATAGTATATA
+TTTCTGAAATTCTCTCAACAAAATCCTTTCCCCTTCCTCATTTTCCCACG
+TAAAGTAAAGTCAAAATACATTTTAATTACCATTAATACCTAAATGAACC
+AAACAGGTCGGTCTTGCCCTCAATTCTACCATTTAGTCTCACGGCTTTTG
+TACTTGTTCACCCACTTCCCCCATTCTATAATCCAACCACACAACTTTTG
+GCAACAAAGTGTTCAATCGAAATGGGACACTATTTGCTATTCCTATAATT
+GACAGGCTGGTGGAAGGAGGAAAGCAGCACACGACGAAAGGCATAAAACA
+ACTTGGCGTTGTGTTAATCCCACCCGTATTGCATTCTATATTAGGTCGAC
+AAACAGTTCATTCATGTCGATTTTCGATCATTTCTCAGAGTTTTGCTTCG
+AATTGTAGGTTCATGGAGTTAGCCATTCTGTCTATTTTTTCCGCTGAATT
+TTAAGATGTTTAATACTTATTTGCCACCTTTTCGACGGAATGACATGTAC
+CGGTCAAATCTTGGAATCGATCTAAGAGATGACAATTTTGAATGTATATA
+CTCAAAATGGGCTCAAATGAACGAATTTCGTAATGAATTTTTTAAAAACT
+TTTTTCAAAATTTTTTATGGTGGTTCAAAGTTTCGAAAAAATTGACCGGT
+ACATGTCATTCCGTAAAAAAAAACGCGCTTCTATCTGAAACAACAATTTT
+TTTGATAAAAACTTTCAACTACAAACTTGTTCTTTACAAAAAGATCAACA
+ATTTATTAGTTGAGCACTTTTCTGTACAAAAAATTATCCGCGCAGATATG
+ATCTACCAAAGTGAATTTGGAAAATTGGCCCGTCAATGCTTCGTTGCAGT
+GCTATTTTAGGATCTTTGAGAGCTCGCCGTGAGCTTGGCTCTGGAGATTC
+GCAGCTAAAAAGGAGTAACCGTTTCTTTAGGAGTAACCGTTTCAAGACAT
+GGGCTATCGAATGGCATAGGTCTCATATGCAAGTCCGATGGGCACCTTCT
+GACGGTTCCCTAGTCAGATAGAAGCCAAAATTTGGGCGAGGTATGCCCAT
+TGTCATTCTAACTGTCGAAAAAGTGGCCTCCGCCAAGACGTGATAACTAT
+TTCTCTCAATTACTCTGCACTCCCAATAAATCCTACACACCGTTTGAATT
+GAGTCATTCAAGTGTCAGTTGTTCAGTTTCTAGCAGTTGATACGTGTGTG
+TGTGTGGTGGTGGTCAACCAACTGTCGCCCTTTTGAACACACACACACAC
+ACATACTTTTCCTGCCATATTCCTCCCCAAGAAAGAGAGAAAAATAAGTT
+GCATCTTTTCTTTTCTATATCTCTATCCACTAACACACCCTGTTATTCGC
+ATGTTCTCTCCATTCTCCAAACAACGCAATCAGTGTCCGCCTAAATCTAC
+ATAATCGATTCAGGGGGAATTAACTGTGTAGTTTTGTAATACTTTTCCTT
+AAGGTTCTTGAAATTTTATATTTATAACCGACCGATTATGCCTAATTATA
+ATTATAATTTAGAGAATTTTTCAATTTAACAACTATTGCGATGTTTTGAA
+TTTTTGATAAAACCGGAGTATTTTTTCAAGAAATTCTGTTTAAATTAGCT
+GAAAAATTTTGATTTACTAGTTTTTGGTTTGCCTCAAAAAAAATCGGTAA
+AAATTTTTTGGGGCTTTTTTCTCAAAAAAAAAAAAAGAACGATTCAGGAG
+ATTTTTCATAACTTCGAAACTTAGTGCAAAATCTTTTACGGGGTGTCGAT
+TTTTTGATATTCGAAAAATCGGGTTATTGCTCTATTAAGAAAAATTATTT
+CCTGGACATATTTTCTGAAGAATTCCTCGTCTTTTCCCATTTTTCTACAA
+TTTTTCCTGATTTTTCATAAAATTGAAACTTTCGCTGTTCAGTTTTCCCT
+TCAAAATGAATTTTTTCGACGACGAATGTTCAGAAAGTTAACAAATAATT
+TTAAGATTTTGTCAAATTTTCACACACGTACTTTTCCACCAAAATTGACA
+AAAAACCCTAAAATTTAATTTCTAAAATTTTCAAAAAATCGTGATCCATT
+CTTCCTTATCATGTTATGTCTTGCAAGCGTTGCCTCAAAGTCATCAATCA
+GCTAGTTGTCATCAATTCAGCGATACTTAGAGATTGAAAGAATGAGTAAT
+TCATCCTTGTTTCTTCTTCATCTCCTCACTTCACTTCCAATTTTCCATCT
+GTTACCAATCAATTTGGCCTGGCGATTAGTCATCTATTTGTTCGTCAAAT
+TTGGTGCAAATTGGCTCGTGTCACTGATAAGTGGTTATTTTTTCTTTTTG
+GTTGATAAGGTTACCTGATAAGGTCATTTCCTTTTTGCGCCTTTTTTCCA
+GTAGTAATTCCTCTAATGTTCGTTTTGAAGTTACTAATCGAAGTTGTTAA
+AGTATTAGATTTTTTTAAAATCAATAGGAATGTTTTTTTAATACAGTGTT
+AACAAAATTTTATGTTTTAAAAAGTTAAAATAAATTTTAAAAAATCTCTG
+AGTTGAATTGTTAATTTTTAAAACTATAAACAGCATTGGCATTCATAAAA
+AACAAATTTCGACAAAAAATTCGTAAAAATTGCTGAAATCGCACTAAAAA
+TACTCAAAACACTGAATTTTTTGCTCATAAAATCTGGAAAATCAAGTCGT
+TTTACTTGATATTGCCATAGGAAATTACAAAAAAAAAGTGATTTTATTAA
+AGGCTGGTCAAAATTTCATATTTGAACAACGTTTTATAAAACCGCTGTCA
+GAGTAGAACAATATAGGTGTAAAATGTAGTTAAAAACTATTCTTCGATTT
+TCCTACATTTTTTTTTCTGTAAATTGAAGTTTTCTCGTAGAACAAGAAAA
+TTTAAATTTAAACCAAGTTTTTAAATTTTCAATTAAAAAAAACTACAATT
+TTCGATTTTTAATAAAACATTTTAAATCCCAATTTTTCTTTCAAACATAT
+TTTCCAATGCTGATTCTGAATCCATGAAGTCTTAACACTTCAATTTCAAC
+ATTCTGTTGCAACAAGTCGTCCCATCTGACCAATAACAAGGGCTCATCAA
+TCACTGACGAGGGCCCCCGGGCGCCGCCATCATTTTCCTCTCTTTCTCTC
+TCTCTCTCTCTCTCTCTCTCTCTCTTTGTTTCTAAAAAGAAGGAAAATGA
+GCTGCAATTTATCAAATCCACGGTCTTTTTCCCTCAAATTCTCTGCCTCT
+CTAGTCTTCTCCCTCATGGTCATTGTCGCCACATTTGTGACTCACAAAAT
+GGGCCGTATTATACAAAAATAATTAAAGTTCAATGCGTATGCGTGTGTGT
+ATTTGTTGCTGGGTGAGGGCAAATGCACATTAGCCACCCACAACAAACTT
+ACGTTTTTTTTTTTGTATTTTGCCTTTTTCTTCTTGAAGAATGGTGTCAC
+ATCACATTACGACCTTTTCTTTGTTACGGAGAAAAGAAGATTGGAGCGGA
+ACTGACTGAGGTGTGAATACTTTGTTGGTTTTTTTGGCTATACCTATTAG
+TTACCTTATTTTTGAGAAAAAAAAATTTGAAGCATGTTATTTTTCGAGTT
+GTTGGTAGGATGTTGATAATTACTGTTATCGTGATTTTCTTATTAGAAAT
+TAATTTTTATTTATTTAGTAGAATTGGGGATTTTTATTCAAATGATCCAA
+AATAATCTTTCGACACTGAAATCACGACCATTTTTGAGCCAATCAACGTT
+TTCAAACTCCGCCTACTCTGTCTGATTGGTAGGAAAAGTGGGCGGAGCAA
+ATTGCTGATTGGTTTCGAAGTTCTCGACTTAGAAATACCAGAGTTCATCA
+AAACTGAAATATTGCGTTTTTAAAGGATATATTATTATTATTATTATTTT
+CTCTCGATTTTTTTATTCTGTGGTTGCTCTGAATTTCAGATTATTCGAGA
+TAGTTTTCGATAAAGCGACAGATTGTTCAGTTTCTGAATTTTCCATAATT
+TATCCTCTAAAAGTGAAAGTCAAGGTTTCGTTCTTTGCAAAAAACTCATT
+TTTTTGAGAGTTTTCGGAATTTTGGCTCGCATCACGCTCCAATAAATTAA
+TTCAAAATTTCGGAAATTATTAACTTCTTCCATTTTATCAATACTGTGTT
+AATCTCACTTTTCTAATTTGAAACAAAAATTGAATTTTCATCGATTTCCA
+AAATACTTTACATGCTTGGCAATTGAAAATTAGTTTTGTTTTTCAAATTC
+TCAGTTTCCAGCCACTGAAAACATTGCGAGCCTCCATTGGGTCCGCTCCT
+TCCTTCCGAAACACATTTCCCAGTACTCTTTCCAATCTGGTCAACATTTG
+AAAGGCTGTTGGGGGGTCGAAAGGCAATAAACAACCGAAAAATAGTTTAT
+TCCAATGTCATCGAATCCTCCCTGGCTTCTCATATTGTTGCCAAAAATGA
+TGATGGAAATTGTTTTTCGTTTGTATACACACACATCATCCTGTGCCACA
+CCTTTTCCCCACTCTTTTTCCCGACGAGCTTTTTCATTCGGAAGGCGACA
+CAGATAGCAATTACCGACATATGGAACCAATCGTACTCTCTCCGCTGACT
+GCGACTACCTAATTAACCTTTTATTGAAAAAATGAGAGAGAGAGAGAGAG
+AGGATATGAACGGAAGAAGAAAAAGAGGCAAAGCAATTGTTTACTTGTTT
+TTCGAAACAATTCAAAATTTTGTTTGGGCTGTGCGCCTTTAAAGATGGAA
+AAAAAACGGAAATTTTCCAGCAATTCGTTAATTTTTTTGTCGGCAAATTT
+GGCAAATCGGCGAATTACCGGTTCGCCGATTTGCCAGAAATTTTCATTTT
+CGGCAACTTGCCGGTTCGCCGATTTGCCAGAATTTTTCATTTTCGGCAAT
+TTGCCGGTTTGCCGTTGCCGGAAGTGTTTAGAGGAATTGTTTATGAGACG
+GAAGCACTGTGCCTGTTTGCCAATTAAAATTGAAATTCTGAAATTTCCAA
+AAAAATGTGCACAAGCACCATTTGCCAAAAACTTTTTCAGTTGCCGGTTT
+GCCGATTCGCCGGAAAATTTAAAATCCGGCAATTTGCTAATTTGCCGGAA
+AAAATCGTCTACCGCCCACCCCTCCACCGAATTCGGAAATTTTGTAAAAA
+ATAACTTTATTTTTGGGCCAATACGATACTACTTTTCCTAAAAAGAAGCT
+GTTACAGTAATCAATGTATCATCTTTTCCATCTCGAATGGTACCTGTGTT
+TACCTTAACTGTCACATAACTGTGAAGAGTACTTGAGATGACAAGTAGTC
+TTATCAGAAAACCTCCCCGCTTACTGCTTCTCGGGTGTCGGGTTACCGTG
+TTTGCTGAACGGTTTTTCGTAGGGATTACTGTAGAGAATTGGATGAGTAG
+TTGGGATTAGGCGATTAGGGGGAAATTGGAAAACATGTCTGTGCACTCCA
+TATGTTTCTAATAAGAATCCTTGGAAATTTGCATATAACTCAAGAATGGT
+ACTGGTCCAGTTTCGTTTTGTTATCTTGATTCTTCGAAATGGTGCTCACT
+CAACTTGATTCCATCCCCAGGACGCTAGTTATTTTCGTAATCTCCGCGTT
+CGATCTCGAGCTCCTCCTCTATGGAAATGTTAATTTGTGAGGGCTATCGC
+GTCCACAGATTTATAGCGTCCGTCGTGCGGTTTCGCTGGGTTCTCGCAGC
+CACCCCCCCCCCCCCCCACTCATCAATCGCGTAAACTTTTTGTGAGCACG
+CAGCACACAATGTGCTCAGGAGGCTTCTGTCTCTTCGGAGATCCAACATG
+TGGCACCTCCTCAAAGTGTTCACTGGCCTCCTCGGCTCGGCAGTCAAATT
+TATTCATCTCTTTGGAGATTGGCTCACAATTTTTTTGATTTGAATTCAGT
+GACTATTTATCGATTTCTAGGGCTTCTATGTAGGTTGCCTGTGTGCCTGT
+CGTCTGACGTTAAGGCGGCCTCCGCCTGCCTCTCGCCTCAATCCGTGCCT
+TGTGCCAAAACATACGAATTAATTCGATTTTTATCAAATTGATAAAAATG
+AGAAAATTAAAAATTTGTAAATTCAGACAGGCCTGAGGCAGGCAGATTTC
+AGGCAGGCATCAGGCTCAGAAACCGCGCCTGTCTACCATGGAAGCCCTAC
+TGCTATGTAACGTTTGAGATATTCGGTTCAGATAAAATAAGTTGAAGTTA
+CGCGAAGAAATTCTGAATTTTGAATATTTTCCAATAGTTTCTAATAGTAT
+TTAGATGTTGTATTTAGATACTGTTGCTACAAAATTTTTAGAAAATTCCG
+TGGTAAAGTTCAAAAGACTACTCTTTCTCTGAATATTGGTTAATAATATG
+AATCCGTTCTGCTTTTTTTCCGTATTCCAATTCTTGACGACTTGATATGA
+AGCCAGCTCAAATAATAGGCCTCCCACGTAGTGTCAGGCTGTCCCAATAC
+GGTTTGATCGACAAAAAATGCTGGAGTGTTATGCCCTTCAAAATGTGACG
+TAAGCGCGCTCTTAACCATGCAAAATCAGTTGAGAACTCTGCGTCTCAAC
+TCCCGCATTTTTTGTAGATCTACGTAGATCAAGCCGAAAGGATACACTCT
+GTCACCACGTGGCCTCCTAAGGACTATTTTGCAAGGACCTAATTTTCTGA
+ACCTTCACAAATTGATCTGCACCGTTTGAGATCGATTGAAAAGTTCTAAA
+ATTTTCTGTCCTGTATACTTTTTTCTGTACATAAGTCCTACCGAAAGGGT
+CCCCCGCGGTAATAATTACCCGTCAAAACAATGTGTACTACTAGCCGAGA
+TATGAGTTGTTATTGTTGTCATAATACAACAAGATTTGGATCACCGCCCA
+ATTTTCTTGTCAAAAAGTTCCGCTTATCTCGTTTTCTGCTAATTAGAGAA
+TACTCTATGGGAATTGGTTGATCCACTCCATTAGTGAATGTTCCCCCAAT
+AACCATGGAGCTGTTAGAACAAAGACGAAAACCCGCCAGAAGACACACCT
+TCTTGAGAGCAGGTATTAGAAAAATGAATGAAAGGAATTGGGAGGGGAAC
+CCGCGGTGGCCGAGACTTCCCACTTGACCCGATTTGTGCACATACGCAAT
+ATCGATGAGGAGTGGTGGTCCATTCGATACAGTCTTGCACCATGTTTGTC
+GAAATGCTATTTGGTTGGCTGGCAGATGTTTTTGGTCCAATTTTCTTGTC
+AAATTTTGTCTTGATCTGACAGATTTTAGGATTCTTGGAATTCGACTCTT
+CACCGAAAAAATATAATTTTTCGGAGTTTGTTCAATTTTTCAGTATCCTG
+ATTGGAACATTTTAATGTTTTACAAAATTCGATTCTAAATTTTAAAGCAC
+ATTTTGACCTAGTAGGACTTTCGGAATTTTGTAGCCTTTATAAAAAATCG
+GTGGCCAAGTTTTCTATAATTTTTTTACGTTTTGAAATTGCCTTTTTATG
+AATTTTAAAATGTGGAACATTTTTTGAATGACTTAGTTTTTCAAATTCCA
+CGTAGTGTCAGAGTGTCCCATACCAGTTTAATCGACGTTGATCTACAAAA
+ATCGCGGGAACTCTGACGCAGAGCTCGCAACTGATTTTGCAGGGTTAAGA
+CTTGCTGACGGCACATTTTTTGGGAAAATTTTCCGCATTTTTTTGTAGAT
+CAAACAAATTTCATATTGCCTCGATTTGTTCGCTATAGTTGTCTAGTTTT
+GAAATCGTTGGAATTTCTTGAAATTCGAGTTCTTGAAACATTTAGGTTTT
+CACCTAGTTTTCTCTGCGTGTTTTTTGTGTTGAAAAAACGGTTCTCAGAA
+ATTTGACTGCTTTGAAAATTTCGAATTTCATCTCCAAAAAAAAGTGAACA
+ATTCGTATTTTTCTAGAATTTTTGGAAATCTCTTTAAAATGAGTTTTTCT
+GAAACATTTTAATCTTGAAATAGTCAGAGTTACGTCAAATTCTATTTTTT
+GAGGAATTTATTTTTTGTGAGAAGAAAACAACAAATCCGCAATTTTTTTC
+CGAATAATTAACCAATCCAAGATCCCCCCTCAAACCGGATGGCATTTATT
+CGGATCCCGGCAGGTGTTCGAATGAGATATGTATCCATTAACACATTGTG
+CATACACATAGACACATTGTCAACGTATGCCGTACACAACAAAACAACTG
+CGCTCGTTCGCACCTCAATCCTTTGATGTTCTCCGCCGGGGGCTCCTGTA
+AGGTCAGGAGTTTTCTAAAAATGTTGCCTTCTTCTCCGTCTTCTTCCTCT
+TCATCATCGAATATTCCAGAGGGGGGCCGACACGCTTCACTTGATTTTCG
+ATGGCAATTTGTTTGAAGAATTCAAGAATTCGAAGAATTTATTTGGAAAC
+TCACTACTCTCTTTTTTACGTTTACATCCAACTTTTGGCACTTAGGCGCC
+TCCAACTGCAACCATATGGTGCTCAATGAGCCGAGAGGGATCATCTGTGA
+ATTTGGTGTTTTTTTCTCAATTGGTTGCCTATTTGATTGGAGAGAGATTA
+ATTTGCATACAATTACCTCTATTTGGCTCAGGGGTGGACGGATATTGCCG
+TTCGGCATTTTTTGCCGACAAGTACGGCAAATCGGCAATTCGCCGATTTG
+CCGGATTGCCGGAAATCTTGATTTTCGGCAAACCGGCAAACATCAGCGTA
+CTATTTTACTATTCAAAATAAATGTAGGAACATTCATAGGATGCGTACAA
+TTTTGCCGATAAAATTTAAATTCTGAAGCTTCAAAAAAAATGTGCAAAAC
+CACAATTTGCCGAAAATTCTAGCCGATTTCAATTCCGGCAATTTTTTGCC
+GAAAAAAATTGCCGCCCACCCCTGATTTATATTCAGTCTGTTACCGATTC
+TAGTGAGGGGTTTCCAGCCTTTGCATGAATAGGTGTCTGCTACATTAATT
+GCGCAATCCACATTGATACAGAGCAACCTCAATTGTTGTTTTTTCTGTGG
+CCCGTTCTGCTCGTTACACCTATAAAAAGGTGGTCAAACAAGTCGTAAAA
+TTTGGGTCATGAGATGGTCCCTGGGTTAATTGGAGAAGTGCCGTCATTGA
+GAGAGAGAGAGCCAATTACGTATGAGGTCTGCTCTGCTCTCGGGAAGACT
+CTATAACCCTTCGTTTTTGGCGGGAGATATGAGATATTTTGCTGTAATTA
+TCGCACTTGTTTTGGGTATTCTCTTTTTGTATGATTTACCTAAAATTTTT
+GAGCAGTTGTGATTATCCTATTTTGTTTCGAGAACCTAGAAATGTTTCCT
+ATCATAGTAACCGTTTAACTCTGTGAGTATAGTTTTACTTTAAGTTGCTC
+CGTTTTTTATTTGACTAGCACAGCTTTTTTACATTGCTCCGGTTTTGGCC
+AAAGGTTTTCTGTTTTTTTTTTGCAGTTCTGACTTATTCTGGCCTGCTTT
+ACCCAGCTAAGCCTAGGCCCGGTTACAGTCCATAAGACAACATTTTTGAA
+CTCAATAATTGCCGAATTGCCAAAATGCCAAATTTTCGATTGCTGCCCGT
+CTGAGTAAGTCTGAAACAGTTTGTGTGAAATTGAGCCGGAAACTACTCGG
+AGTGATGTGGCCACTTCCCTATTTAGTTTCTCGGTTGATTTTCACACTTC
+CCGCCGAGAGCCCGAAGCATCTGCCAGCTGAACGGTTTCCGTCGTTTTTC
+ATGTCTATCGCTAAAATGTGCGCGTTACACACACATAAACATCACTTCTC
+TCATAAAGTGATGGATAATTCGAGTGGATTGCATCTGACACCACACTTCC
+GATAATCGCTTCGTCGTCTTGTCATCATCGTCGTTTTCTTCGTCTTGTTG
+TCGTCCGGTCCCCACACACACATCAAAACGGCTACTTCCGACGTGTCGGT
+GGTTTGTGTGTGTGTCAAACGGCACCACCACAAGTGGTTGCCCTCGCCCG
+TGTGCTAATTCGCATTTTGTCTTGTTAATCACGCAATAGTGATAACAATC
+GCTTCCGGACCATTGCTAATATAATATATTGGCTACCGCGGGCATGTCTT
+GGCAATAACCTTGATGTCAAGTTTTATCGTTAAAATGTGAAGCTGTATGA
+TTGCGAAAAATTTGAAGTTTTCCCATTCAAATTGTAGGCATATTTGAAAA
+ATTTCTGAAGATTTATATCTGTCGTAAGTGGAACGGTTTATTTGGTTTCT
+TGGGTCTCGTCGCGAAAAGCTTTCACTATGGTTTGAAGCACGACTGGGCG
+ACAATCGAAGTCGAAGTTCGGCAATTCGATAATTCGGCAATTATCGAGTT
+CAAGATTTTCGAAAGAAAAACTCAAAAAATAATTTTGAAATCTATTTATT
+AGTTCTGGACACGCGGAGTCAGAAAGTCCCATTTCGCTTTGATCTACGAA
+AAATGCGGGAGTTGAGACGCAGACATCTCAACTGATTTCGCATGGTTAAG
+AGTGTGCTGACGTCACAATTGTTCTGGAAAAAAATTCCCGCATTTTTTGT
+AGATCAAACCGTAATGGGATAGCCTGGACGTAGAACTCGCCAAATCGTAG
+ATATATGCATAATGAAAACTCTAGAGTTAACTCTGCCACCCTCATAAAGT
+GAGTTAGAAACATTTCTGCTCTGAGGAACTATAGAACCCCCTTTCAAGTC
+GATCGTCAGCAAATTCTAGAAAGATCTGACAGTGGCCGATTTTTTAATGT
+TTCTAGGCCACGTAAAAAAGCTGATGTCTTGTTACTTTTCAATTCGAAAA
+TCCCTTTTTTTAATTTTTCGGCAGCACCCGGTCCGAGCCAACATCTTCCT
+AAACACTTCAAAACCCCGCCCCCTTCTGCCCTCCCGGGTGTCTCCGTGTT
+GTTCAGGGTGTTGTCCACCCCCTAGACACCCAACTGACCATTCACCCGTC
+TCCTCCTCCCCCTCTACAACAACCACCACCACCTGATCCATTCCATTATA
+ATGATATTCCGCATACTTGTCATACAGAGAATACCCGGTTTGCTGCTGCC
+AAACGGTTTTCATTTATTCCATTTCTCACTCCTTGATTGTTGTCAATTCT
+TCGATTCGATGCGGCAAAACTAGCGCCAGTGGGGAAATTGCTTTAATAGT
+AAACAATTTTTTTTTAAATTTCCTATATTTTTTGTATAAGATTTTCTTTT
+TTAATTGCAAATCCCATGGGAAAGTCTCAAATTGCATAAAATTCCAATTT
+GAATTCCCTCCAAGATTTCAATGTTCGATGGAGCGCACTTGAATTATTAT
+AATTTTTATCAATGAATTTTTTTATCATCTCTGACTGATTTTTCACGATT
+TTTTGTGTAGTTTTAGAGGAAATTTACTGAAAAATCCAAGTTAAATGTAA
+ATTTCCGATTTTTATACAATTTTTGGACTACTTTCCCCGCCGCCACCGCT
+AAAAATCCCAATTTCCTGCAAGTTTTCACCTGCTCTGACTCATTTCCGCG
+AGCGCGCGCGCTCGTACTTTTTATCTTTTACTATTTATTTATCTCCTCCA
+AAAAAAAATCCCGTTAATTTTTTTTCCCTTACAATTTCTCATAATTTACT
+CATTTAGTTTGGCTTAAAAAATGCTAAATTAAATTTTTTTTTCATTTCCA
+GATCACATGACACAACGAAAATGAGGAGAAAAATGAAGTTATTCCTATTT
+TTATTATTAGTAATTAATATATGTCGGTCGGCCGCTGCTAACGGTGACGA
+ATGCCCGAAATTGTGAGTTTTTCGCTTAAAAATCAGATTTTTTTCGAATT
+TACTGTGAAAAAGCGGGGGTTTTGCCTGAATTTTCACTTAAAACTGCTTT
+TTTTTGCTAAAATCCCGAATTTTTCAGAGAAAAATAATTCAAACTCCATT
+TTTCAGCTGTAAATGTGCTCCGGATCCGGTGCAGCCGACGTCTAAACTCC
+TATTATGCGACTATTCTTCGAAAAACACGACAATTACACCTATTGCGTCG
+TCGAATTATGATCAGGTTGCTAATATTCGGTGAGGTTTTTTGATTTTTGA
+ATGAAAAATTTGAGAAATTTTTAAAAATGGGAAAAAATGTGATTTTTAAA
+TCAAGATATCGGAAAATACGAAAAAATTTCCAAGAAAATGGTGGTTTTTA
+TCGAAAAAATGTTAAAAATGCATAGAAAATTTGGATTTTCGAGTTCGAAA
+TTTTCTGAAAACAAAAAAAAAAGTTTTTTTTTACACTAAAACATTAAAAT
+TGGATTTTTTTTTCCGAAAAACATAATTTTTCAATTTCTAACAGTAAAAA
+GCTCACAAAATTCCTTGAAAATTGACAAATTTAGTATTTTTTACACGAAA
+AATGCATTAAAATTGAATTTTTAAAACAATTTAAACTTAAAATAAAATTT
+TCATTTATTCTACACGGTAAATGTATTAAAATAATTAAAACTTCGAAATT
+TTAAATTAGAAAAAATCAAATTTCCTCCTTATTCTCAATTTTTTTTTACA
+GCAAAATTTCAGTTGAATTTTCCCATAATTTTGAATTAAAAATGTGTTTT
+ATTCCAAAAAAAAACTATTTTACAACAAAAAACTAGATTTTTTCCCAATT
+TTCTATGAAAAATTTAATTTACCAATAACTTATTTTCTTTTTCCAGATCA
+CTATTCATATCTTGTGATAATAATAATTTCCAATTTCCGGATGCCTACTT
+CAAGTCGTTAACCGCGTTGCATCATCTGCGGATAGTGGTGAGTTTATTAT
+ATTATCAGCTGTTCTCTACAGAACATCTGCTTTTTGCGTGTAAATTTAGA
+GGTCAATTTTCGGAAAAATTGGAAAAATTGGCCTAAATCTCAATTTGAAG
+TAGATTTTCACGTGTTCAAAAATGTTCAAAAAATTCAATCAAAAATTCGA
+TTTTTGGAATACTTCAAAAAAATTTAATTTTCTTCGAGAAAACCGGTAAA
+TTACAAAAAAAATTCGTTGGCGATTTTTTTCTGTAGTTTTCCAGAAAAAC
+AAACGAAAATTTTAATTTTTAATTTTTAAATTTTCCAAAAAAAATTTTTA
+AAAATTCATAAATATGTCCATTTTAATTTTAAAAATATCGGAAAATATTC
+AAAAAATGAACTTTTCTATCGAAAATTTAACAAGAAAAAATTACGAAAAG
+TTCATTCAAAAAATTAAAATTCTTCTATATCTGAGGAAGGCTAACAGTAA
+TTTTTTCCCATTTTTTGACTCTTTGAGCAAATAACCGTATCACTAATTAC
+CTTAACCATCAAAAAAGAAAGGTGTGCCTGTCTTCTATTCATCCTCCTCT
+CGACACCAAATTCTTAAGAAGAGCCCCCCACTCGGATGTCTCTAATTAGG
+CACAAATGTTACGTCATTTTGTCATTTGTACGGCCACAGATGACCTCCGG
+TGTGCTTGGAGGACTGCGAGAGAGGAGGATTAAGGGGATTTTTATGTCCT
+ACAATTGATTTTTTTAGGTCAAAAGTAGGGATTTTAAGGCCAAAAATAGA
+GATTTTTTAGGTCAAAAGTAGGGATTTTAAAGCAAAAAAAAAAAATTTTC
+GGCCAAAACAGTGGTTTTTAAGGCCAAAAAATTTAATTTTTCCGTTTATG
+ACACCTAAAATTGGGGTGAAATTTTTTTTTCGGATAGAAATCTAAAATTG
+CAATTGTTAATTATTCCAACATTTTTTTTTGCATTAAACGTTATTGTAAA
+AACATTGAAAATCACTTGATTTATCCGAAAATTTCATTTATTTCAGATAA
+ATATTGTTTAATAAAAAATGTGTTAAAAAACATGGTGCATAGATATATAG
+ATAATTTTGTAGAATAATTGAAAATTGCAATTTTTAACTTCCTACCCGAG
+TAAACAGAATTTAAATCCAATTTTAGGTGTCATAAACGGAAAAATCCCAA
+TTTTTGGCCTTAAAAAATCCCAATTTTTCGGCCTAAAACTCCCTAATTTT
+GGCCTAAATCACCCTATTTTTAGCCTAAAAAAGTCCCCTGTTTTTCCATT
+TTCCCCAGGAACTCGTAGAAGAACATGTGTTAGGCGTGAAGAGGTTAAGC
+CGATTAGCCATGTAATATTCAATACTTGAGTATAGAAGGGCCAGAAGCAG
+CAGCAGCAGGGGGTGCTCCAAGAGCACCACCTCAACAGATGTATAAAGTG
+GTTTTCGAGTAGATTTGTGGTTTTGCACACGGTGGAAGAAATCTGAAATT
+TGAATTTTTTAAAGCCATTTTTGTGCTGAAAAATGTACAGAATAACCGAA
+ATTTCACCACCCTTTAAGGTACGGGAAATCTCCGGGAAAAAGGCTCAAAA
+ATTGCATAAAAATGGAGATTTTAAAGCTAAAAATAGCTATTTTAACAAGT
+TTTTTTGCAGGGATGCGAGACCACACATTTCTCTGTGAAATTGTTCGAAG
+ATTTGGCCGCTTTGAGAAGATTGGAACTCGATCAGGTACATTTTTCTTGG
+AAAATCTAGAAAATTTTGCTGAAATTGGCTCAGAAATGTCCTAAATAGTA
+GAATTTTTCATTAAAAAGCCTCTCAAAACGGCTTAAAATTAAGTAAAAAT
+CGACATTTTTTCACAGATCTCCACCGCCTCAACCTCTTTCGAAATGACCG
+AAGACGTCCTAATGCCGTTGGCTCGTCTCGAAAAGTTTTCCCTCACGAGA
+TCACGGAATATCGAGCTTCCACAGCGACTTTTGTGCTCTCTGCCGCATTT
+ACAGGTATATTTTTGGGTAATTGATAATTCGCCAAAAAGAACAGCAGCCG
+AAAACTCAAATTTTTCACGAAATTTGCCGAAAAACTAGATTTGTAAAATA
+AAAAGAATGCAAGAATTTTTAGCTTAAAAATCTCAATTTTGAACGATTTT
+TAAAGCAATTTCAGTATGAAAAATCCAGATATTTTTTGGGTAAAAATTTG
+GTGAAAACGCGTTAAAATCTGCATTTTTGAACGAAATTCGCCAAAAATCA
+AGACTTTTGTAGTGCATTTTACTGTAAAAATGTATACCTATTTTCTATTT
+TTATGCGTACTGCGCAATATATTTGACGCGCAAAATACCTCGCAGCGAAA
+ACTACTCTTCAAATGACTACTGTAGCGCTTGTGTCGATTTACGGGATCGA
+TTGATAGAATATCAAAATTAGAAATAAATGGGAAACTACTGCGAAAACAA
+AAATTTATTTCAAAAATTGAGTCCGTAAATCGACACTACAGTAGCCATCT
+AAAGAATTACTGTAGTTTTCGCTACGAGATATTTTGCGCGTCAAATGTGT
+TGCGCAGTATGCATTCCCATCTTGTTCTCTACATTCAATTACCACCACAT
+CTCACAGAGAAGGAATTAGTTGTTTATTAGTACGTGGGGGGGGGGGGGCT
+TTAAAGCTTACTACTTCTTCTTTCTTTCCACTTTCTGACGTTCAACCATC
+TGGTATTCCTGGCGGCGGGGCAATTGAAAATGAGAACAAAAGGACATCGA
+TGGAGGGAGGAGGATTGAGAGTTTGGAAATTGTGAAGAATGCGCGCGGAA
+GGAGGAGGTCAAATATCACAAGCGCCGGAAGTTGTTGTCAGCCAGAAGCA
+ATAAAGGCCTAATTATGATGATGATGAAGAACCTCCCTGAAAGAGAATAG
+CGAAAATGTGAAGTTTCCATCTCAAGGGAGCGATTTTTTAGTGATCATGG
+AGTCTTGAAGTGTGCACATAGTCTACGTGCCCCACAAGAGCCTATGCCTG
+CCTTATGCCTACTCACATGCTCACAGCCAAACTCTTTCGAAATCAGAATT
+CTACATTGTAGAATCTACAACACTGAAGTTTCTGCCATAACGTTGAAAAT
+AGGCACCTACGCCTGAATACGTGCCTGATCAACATGGATGCCATATAGTC
+CAGGCTGTATAGTCGTAAAACAGGGATTTTTTAGGCTCATGGGTTTTTGT
+CGGAAAAAATCGAACATTGAGAAAACCAGAAATTTTTCAAATTTTCGTAT
+ACTATTCCACGAATCGTTTCTCCCGTTTATCGAATCTCCACGTCGCACTG
+TAATTTTTCAAGTATCGTTAGTCCATTCGCCCGAGAAACTCCACAGTTAC
+AAATGCTTTGCAAGCATTTTCAAGAAACCATGGTTCCTGGCATGTTTTGG
+CGCATTCAATAATGCCGCTAATAATAATAATAATGCCTCCTATTATGATG
+TCGCGTTGTCATCGTTTGCTGCTGCTCCGTCAGATACTTTATGGGGTTGT
+TGTTTTCTCCCTCCGCATCAAACGACGTTCCTCTCTTCAAAATGATGATG
+GATATACATATATCTATGTTTATAGAAGAATTGAACCCCACACTTTACAT
+ATGAATAGATGGGGACCTTGTTACCTTGACTATCGGGAAGAGATTGAAGG
+TTCCAAAGACGGCTGGCTGTGGCTCATTAGGCTAAATGATGCGTGATATT
+ATTCGCTCTACGGCACCTCTATGATCCAGGAATAGCAGTCACTGTCAACA
+AGAGTCACCTCACGGCAACAATACTCCGCTAATTACGGTTTGCGGCAAAT
+CCCAGAATTTATTTGAAATTCTAACTGGGTGTTGCAGATGGGTCGAGGAA
+ATATGATAGCAATAATTATTGTTACGTGGCAATTGTAATCCGTCAGATAT
+CGTTTCGAGACCTGCTGACTCAAGAATGTGAAAATGGACAAATTTGGAAA
+ATAGGTAGCGGAAAATTTTCGCAAGTTTTGAAAATTTCGGTCATGATACG
+ATACGAACTCCTTGATTTTCACAGCCCGACAAGCCGTACGCGTACGCAAT
+TTGTCTACCGTATACCTGAACGTTCAGGCTCGTCTATCTCGAAAACAGTT
+GGTCCAGCCTTTTTGTGGGGCATATAAAAAAGGTCAGAACATAAATTCTA
+AAATTTTTTGGACCATAGCTTGTTTCGTTATCACGCGCCCAAACCTGATC
+TACACTCAAATTATCAGTAGAGCGCATTTGCATGGATGTACCACTTGCCG
+GGCCGTGATTTTGAATGGAATATTAAATTCCACGTCACTCTAGTGAATCT
+CCGCTTCTCAATATGCTTCATAATTCATCAAATTCAATTCATTTTCGGAT
+AAGCCAGTTGTAAACAGTTGTGTGTGTGTGAGTGAGCTCATCCTTCATAA
+AATGAATAGAGATAGAACACTGACACTCTCTCAAAGACAAGAGGAATTAA
+TAAATATGAGAGCTCATTAGCTGCTCTTCTCGTGACTACTAATTAGGAGG
+GTGGTACATGAAACAGTGTATGTGTAAAGGGATCCCCGCCGCCGCCGCCG
+CCAATGTCTTTCGGTGTATGGCAATATCCGAGTGGTGTTCTCATTTTGAA
+GAGAGTATTAGGATGTAACGTATCAACTGGAGAGAGATAGTTCAAAGATT
+GGGGATTTGAGATATTTTAGGTGTCGAAATGGATGAAATATAAGCATAGG
+GAGGAAATAAATAGAAAACGATATACTTAAATAGCAATAGTTATTTGAGT
+TCTTACTGTAGTTTTCGCTAAGAGATATCGCGCGTCAAATAAAATGCTCT
+ACGTACGCATTCTCATGATTTATTGTTCCCGTAATATAAACATAGCAAAC
+ATTTTTAATGTTTAAATATTCCTCAATGCTATTGAAATTCAAATTAGTAC
+AAAGAAAGCAATTTTTCGATTTTTTTAACGAGAAAACTAAGTTTTCATCA
+AAAAATATGTAGATTTTGATGAAAATAATATGACAATTTATTTAAACCTA
+TATATTTTTTTGTCCAAAACAACTTTACGAAAAAAATTTTTTTTTAAATA
+AAATTATTGGATTTTTCGTCAACTTTACGATAAATTCCGAAAAATTAACA
+ATAAATATAGGAGAAAAAAATCCGAAATTAACGAAATCCCCTGTTCCAGG
+TTCTGAATATCTCGTCAAATGAGCTTCCATCACTGCGAAGAGAGGAATCG
+TGTGTCGCTCAGCAGCTTCTGATCGTCGATTTGTCTAGAAATCGGCTCAC
+CAACATCGAGTAAGGGATTTTCCGGATATTTTATAATTTTGATCTTTAAA
+AATTTCAAAGTTTGTGAAAATGTGAAAATCTAAAAATGTGGAACAAATAT
+TGGTTTTATCTATTTAATACCCCAAAACTTTGAGATTTTTCCGTTGAAAA
+ATCGAAAATTCGAAAATTATCTCAAAAATTTCAGGCAATTCCTACGTGGC
+ATCCCGGCAATCCGGCAAATTTCGGTGGCTTACAACTCGATCGCCGAGCT
+CGATTTATCGCTGGCAACTCCATTTCTACAACAACTCGATGCTGAAGCCA
+ATCGAATCGTCGACTTGACGTCACTTCCAGGCACTGTTGTACACGTGAAT
+TTGGCTGGAAACGCGCTGAAAAGGGTGCCGGATGCGGTAGCCGAGTTGGC
+GAGTCTTGTGGCGTTAAATGTGTCGAGAAATGAGATTGAAGCCGGAAATT
+CGTCGGTTTTTTGTGGGTTTTCGGATTTTTTTTTGGAAATTTGAAATTCG
+GAAAAAATTCAATTTTTACATACAATTTTGCGTATTTTGATCATATTTGT
+TTTAAAAATCGAGAAATTTAAAAAAAATCAAATTTCGCTTATTTTCATTG
+GAGAATACATGAGAAAAATATTTTTGTTTCGAAAAAGAAAAATAGCCAAA
+ATTTAATGCTATTTTTTCGAAAAATTTCGATTTTAATTTTTGAAAAAGTA
+TTGAATAATTTCATCAAATTTGTTTTATTTTGATGAGAAAATACGTGAAA
+AATGGAAAAAAAATATGAAAATCTTTAAAACAAAAAAATAATCAGATAAT
+TATGCAATTTGGCCTGAATTTTCAAAAAAAAAACTTGGATTTTCGAAAAT
+TTCATCAAATTTTGTGTATTTTCATGCAAAAAAAGATAGGAATTTCCAAT
+TTTTGACCTTAATTGCAAAGAAAAATTCCTAAAAAATTGTAACGTTTCAA
+AATCTCGATTTTCTTCTGAAATTCTCAAAATCTTCATATTTTTCCAGCTT
+CCCCAGAACTCGAAATGCTCGACGCCTCTTACAACAAATTGGACAGTCTG
+CCCGTCGAATGGCTTCAAAAATGCGAAAAACGCATTGCTCACCTCCATTT
+GGAGCACAATTCGATTGAGCAGTTGACTGGTGGAGTGCTGGCGAATGCGA
+CTAATTTACAGACGGTTCGTAGACTTGTTTTTTTTTTTTTTTGAAAAAAA
+ACACGCTGAAAAAATCTAATAAAACCCAAAAATTTGCATTTTTGTTTAAA
+AAATATGAAAAATTGTTCAAATTCCTAGTTTTCAATATTTTCAACAAAAA
+AAAATTCTAGAGCTTCCATGGTAGGCAGGCGCGGTTTCAGGGCCTGACGC
+CGACCTTTCGCCTCTTTTTTGCATTTTTACGGGAATTTTCAAATTTCTAA
+TTTTCCCCATTTCTATCAAATTATTGAAAATCAAATTAAAAACGCGAATC
+GCGTATTGAGGCGAGAGGCACGCAGAGGTTGCCTTAAGGTCAGACAGGCA
+AGCTTTTTAACGCCTAACGTAATTTTAAAACCTGAAACATTAGAAACTTC
+CACACGTTTGTAATTTCACTGAATTTTACTGCACCTCTTCATAAATTCAA
+TGTATTTAGATAGTGTAATTTTTAAAGGTGGAGTGCCGAAATTAAAGACT
+TTGCTTTTTTAGACCAAAATTGGTCCTAAATAACCGAATTTCGTAATGAG
+ACTTTCTGAAAATTTCTCAAAAAAAAGTTATGGCGGTTCAAAGTTCGGGA
+AAATAAGGTCAATTTTCAGCTAAAATCAAAATTTTTAAAATTTTTTATTT
+ATCACTTTTTGATAAATATTGTGGTCTTTGATTAGGCGGGGCACCAATAA
+AAGTTACATTTTGTGCCCCACTGACCATGAATGTATTTAAATCAACGAAT
+AAACGCCTAATCAAAGTATTTATTAAAAAGTGATAAATATAAAATTTAAA
+AATTTTGATTTTAGCAGAAAATGGGCTTTTTTTTCTCAAACTTTGAACCG
+CCATAACTTTTTTTTTGAGAAATGTTCATTACGAAATTCGGTAGTTTTGG
+ACCAATTTTGGTCTAAAAAAGCAAAGTCTCAAACTTCGGTACTCCACCTT
+TAAAGAACAGTGTAATTTTTTTCTATTTTCCAATCAGTGCAACTCTAATA
+GCAACTCTAAACTTATTTCAATAAACTCTAGGCACAGTATTTTGAATAGG
+CGATCGCGTGACAGTTTTAACCAAACATAGTCATGATGACCTTTTGTCCT
+TACAGAATCTTCTCAAGTTCATGCACACACAGGTGTCATTTACTCTGTCA
+AGTATTGTATAAGTGTGATCCCGAGAGTATTATAAATGGTAGTTAGACCA
+CCCTTATGGTTAAGTTGTTCGTATAATTGTAGGGGTGGGGATCTTACCAC
+ATTTATACGGCCCCCCTCCTATTGTATTGTATTGTTGCCACCAGTCGTCT
+TGAGAATCTCTTTCAATCCGGGGTGACAGAAGGTGTCATATTGTCGGAAT
+GTGTAATAGGTGGGTCTCGAATGGATATCACTAACAGCTGTGAAGGGATC
+CGAGAAGGGTTTTCGGTCTTTCTAGGGGTTTAACTTTCCGCTGTCAATAT
+TATTAATCTTACAAGGAAAGGGTTTTAGTTTACCGTCAGACTTTAAAACG
+AGACATGTGTCATTTGAAAGTGTTCCATAAGTGTATGTCACTCCAAAATT
+TCAAGCGGCAAAGCTCCAGTCTCAAACCCTCTAGCATCGATCTGAAAACG
+TTTCAGTGCATTTTTCACTACTTTGAGGCAAGTAGAATTTCTCCAAAATG
+TTTTTTTTGCAAATCTTCAATGTTTTTCAGAACGTTTAAAAGAAGGAAAA
+CAATCTGGAAAATTTTTGGAAAATTTTAAATTTTTTGAAAAAAATCTGAA
+ATTTCTTGGACCTGGTGGCGTGAAGAAATGTTCAGATTTTTTTCAAAAAG
+CTTAAAAATTTTCCAAAAATCTCCCAGATTGTTTTCCTACTTTTAAATGT
+TCTGAAAAACATTGAAATTTTGCATGTTAGTACGATTTGATAATCGTGTT
+ATAATTACATTACACATACATAATAATCAATTGAAATATACAATTCTTAA
+TTATAACCTGAAATTGAGATTAGATACCTTAGACAATACAACAAATAAGA
+ATGTGATCGATTCAGCAGACCCCTATTTGTGAAAAATGCCTTCTAAATTT
+TATTTTACACTTCTCCTAGTAGATGAACAGCACCTGCCAATAATTTCATT
+GACAGCCGGATGGTTTTTGGCTCCTCTAAGACAGTATAATCCCGTCTCCC
+CCGGGGGGAAGTGGTGTCAAATTGCTTTGCGGAGCAGGTGCTTTTTTCTG
+AATCGAATTGGCTTATTGGTGACGGAAAAACCCCTAATAGAATTGATACA
+ATTTGGTTTTCAAGAGGATTTGGGGAAGGGTTTAGAGGGTAATTGAAACT
+GAGTAGATCTTCGTCTGTCGTGGAGATCAGAAGATTGAGGGAAGTACTGG
+GTTTAAGGGGGTCAAGGAGTACTGTAGCGCATTTCGAATACTACTTTAGA
+TAGTTTAGGTATTATATCAATAGGATAATATATTATCAAGTTGCACCAAA
+ATTGGAGATTCTAGTAGTGCATTTTCTTTATATGCTAGGTATGTATAAGT
+TTCTAATAAGTGTATATACCTACCATGTACCTAGGGGGAGTAGAGTTTGT
+GGGTATTTTGCTTAAATAGACTAAAACGTGTCCAAAACCACCGAATTTCA
+AAATGAGACTTCACAAAAAATTTCCAAAATTTTTTTTATGGAAAAAAGAG
+CAAAATTTAACTAAAATCCGAAATTTCGCACAGTTTTCTTTGTCACAGCC
+GCTGGATTTGAATTTTTCTGAAATTATCACCCTTTAATCCTTATTTTAAT
+AATTTATCTCGCGGAAATTCGTTGATTGAGACAACTTTTAGGCCGATAGG
+CATCCCATCTTGATCATTTTTGGATGCCTATCGGCCTAAAAGTTTTTTAA
+TTTCAGAAAAACTAAAATCCAGCTGCTGTGACAAAGAAAAGTGTGCGAAA
+TTCCAGATTTTAGCAAAATTTGACTCTTTTTTTTCTCGAAATTTTGACTC
+GCCATAAAAATTTTTGGAAATTTTTTGTGAAGTCTCATTATTAAATTCGG
+TGGTTTTGTACCAGTTTTAGTCTATTTAAGCAAAATACCCACAAACTATT
+ACACTTTACTTTAACAAGACACACAATAATTCACAAATGGTGTAGTATCA
+TGCCGGAATTTATATAGGATTGATTCTTGAAGAACGAAATTTTAAATAGA
+TTATTGCAGACTATGTAACACTATTTGTATAAACAATTAACATAGTGTAT
+TGAATAATGACTTTATTGAAATTAATACAGTTTTTGATATACCCATCTTC
+TATTAGTATATCATGCAATACTAATAGGTAATATGCAATATCACTTTAAT
+TGTTATTTCCCATGCGTCGTGTTTATACAAATGCTTTATATACTCGAATA
+GTCTATAATAATCCAATTAAACTCGAGAATCCCAATACAGAATATAGTGT
+TTACCAAAAACACTTGTGTTATTATTCTAATATACATGCACACACACACC
+CACACACAGGTTTGACACCAGTTCTACTAATATTTGCATAATACCATTGA
+GATACCTGAAGTACCCTATAGATATGCACGGGATTCGTTTCGGGCACTGC
+CACGGAAAATATTGAAAAAGTGTGGTAAATTTACGAAAAACAACAAAAAA
+AATGCGATTTTCCAGAGAAATACGAAAAAAAAGAAAAAAATATTTAGAAA
+ATTAACAACAAAAAAAAAAATTTTTTTTTATTAAATAATAAAATGTGTTC
+ATTCTGTTTTTCCCCTTTCAGTTAAACTAGGGCTTCCATGGTAGGCAGGC
+GCGATTTCAGGGCCTGCCTGAAACCTGCCTGCTTCACGCCGGCCTCAGGT
+CGCCTTAAGACGGCTGCTAAAAATTTGAAAAAAAAATTTCAAAATTTGAA
+TTTCCGCGCTTTTTTCGAATTCCTAGAACGCTTTTTTTTAATTAAAAAAA
+AATTTCAGTTGGACCTTTCATCGAATCAACTTCGAGTTTTTCGAGACGAA
+GTACTTCCGGAGAATTCGAAAATTGGAAATTTGAGACTTTCCAACAACTC
+TTTGGAGCTCCTCGAGCCGTCGAGCCTGAGCGGCTTGAAATTGGGTAATC
+TAAATTTATATGAATTTTGCAAATTCTAAAAATCCTAATTTTTTCTAGAA
+TCCCTTGATCTGAGTCATAATAAGCTGACAGAAGTGCCCGCCGCAATTGG
+AAAAGTCGAGCAGCTGAAAAAAGTGGATTTGAGCCATAATAGAATTGCGA
+AGGTTTATCAATATGTGCTCAATAAGATTAAGCAATTGCATACTGTTGAT
+TTGTCGAATAATCAGTTGCAAAGTGTGAGTTTTTTGTTGATAAAAATTTA
+AAATTTGAATTTTTTCTTTTTTTTTAATTATTAATTCTGAAAAATTCAAC
+GAAATTTCCGAAAATTACTTGAAATTTAAATTTTTATCCAGAATTTAGTC
+TATAAAAACGAAAAAATACGAATTTTCGATTAAAAAAATTAATTTATTTA
+AAAACACACTTTCGAAAAAAATTTTGAATTAAAAAAAATTTAAAGTTCCT
+TAAAAAACTATTTCCTCAATTTTTTTTCTGAAATTTCACTCTTTCATTTT
+TTAATTCATTTTTTAAGTCTATAAATACGAAAAAACACGAATTTTCGATA
+AAAACACATTTTTCAAGTTTTTAAAAATAATTTTAAATTGGAATTTTTCT
+TTAAAAAATTGTTTTTTATAAAAAAACACATTAATGCATTTTTTAAAAAA
+TAATTTCTTGAAATCTTCCAAAATCGGTTGTAATTTTAGCGAAAATAACT
+ATTTTTTCCAGTTTTTATTTAAAAAATCCCTCGAAATTTGAATTTATCCA
+GAATTTAGTCAATAAATGCGAAAAAATACGAATTTTCGATTAAAAAAATT
+AATTTATTTAAAAAACACTTTCGAAAAAAAAATTTTCAATAAAGAAACTA
+GTTCTTAAAATTTTTTTTCTGAAATTTCACTTTTTCATTTTTTAATTCAA
+AAAATTTGAATTTATCTACAATTTACTCTATAAATACGAAAAAAATACAA
+ATTTTCGATGAAAAAACACAATTTTCAAATTAATAAAAATATAATAAAAA
+ACATATTACTAAATTTTTAAAAAATAATTTCTTGCAATTTTCCAAAACCG
+GTTTTAATTTTAGCGAAAATAACGATTTTTCCAGTTTTTATTTTAAAAAT
+TCCCTTGAAATTTGAATTTCTCCAAATTTTTTCTTGAAGTTTTTAAAAGT
+TCCATCATTTTCTACTGGAACTTTCAAAAAATGTTCCTTAAAAAATCTCT
+AATTTCCGCTAATTTCTACGTAAAATTTCAGCAAAAAAACAACGACATTT
+CATGTTTTTTTGTTAAAAAAATAATTTTCTTGAAAATTTCTTTGGAATTC
+GATTTTTTTTGAGTTTTAACCCAATAAAATGTATAATTTAAAAATATAAA
+AATTCCAGATCGGCCCCTACATCTTCTCCGACAGTTCTGAACTTCATTCC
+CTGGACGTGTCGAATAATGAGATTTCACTGCTGTTCAAGGACGCTTTTGC
+GAGATGCCCAAAGCTGAGGAAAATTTCGATGAAAATGAATAAAATTAGTG
+AGTTGAAGCACGAAAAACTGCCCAAAAATTAAAATTTTGAAATTTTTGTG
+TTTAAAAACCTAGAAAATCGAGATAAAGTAGGCTTAAAGTTGCTCAAAAT
+CCGCAGATTTTTTGAAATCGATTTTGAAAAGTGCACATGGAGCTAAATCA
+GACTTCAAAATTCTCAAATTAATTGCATTTTCACTCGAAAACCTCTGAAA
+ACTGCCTTCTTCCTATATTAAATCAAATTTTCTTTCAGAATCCCTCGACG
+AAGGTCTCACAGAAGCTTCCGGCCTCCGACGTCTCGACGTATCTCATAAC
+GAGATCCTCGTGCTGAAATGGTCGGCTTTACCTGAAAACTTGGAGATTCT
+CAACGCTGATAACAATGATATCAATCTCCTGACCGCCGCCTCAATGTCCC
+CAAGCACCGCAAACTTGAAGTCCGTTTCGCTTTCCAACAACGGCATCACC
+ATAATGAATGCGGACCAGATTCCGAATTCGCTCGAGTCGCTGGACGTGTC
+GAATAATCGACTTGCAAAGCTCGGGAAGACAGCGTTGGCCGCGAAATCTC
+AGTTGAGAAGGCTCAACTTGAAGGGCAATCTGCTTACCGTAGTGGCCACC
+GAGTCGATGAAAGTCGTAGAGGCTGTGCATCCGTTGAAAGTGGAAATCTC
+GGAGAATCCTCTGATCTGTGATTGTCAGATGGGATGGATGATTGGTGGAG
+CGAAGCCAAAGGTTCTCATTCAGGACTCTGAAACCGCAAGCTGTTCCCAT
+GCCGTTGATGGGCATCAGATCCAGATTCAAAGTCTCAGCAAGAAGGATCT
+ACTGTGCCCATACAAAAGTGTATGTGAGCCGGAATGTATCTGCTGTCAAT
+ACGGAAATTGCGATTGCAAATCCGTATGCCCCGCCAATTGCCGATGCTTC
+AGAGATGATCAGTTTAATATCAACATTGTCAGATGCCACGGGAACTCATC
+AATGGTGCCCAAAAGAGAATTCGTGGTCTCCGAGCTCCCGGTCTCTGCGA
+CAGAGATCATTCTGAGCGGAGTCACCCTTCCACAGCTCCGAACTCACAGC
+TTCATCGGAAGACTTCGTCTCCAGAGGCTTCATATCAATGGAACCGGGCT
+CCGATCCATCCAACCGAAGGCTTTCCATACTCTTCCAGCACTGAAGACGC
+TGGATTTGTCGGATAACTCGTTGATCTCGCTGAGCGGGGAGGAATTTCTA
+AAGTGTGGAGAAGTCTCGCAGCTTTTCCTCAATGGAAATCGATTTTCCAC
+GCTATCCCGTGGAATCTTCGAGAAGCTTCCGAACTTGAAATATCTGACAC
+TTCATAACAACTCCCTCGAAGACATCCCTCAGGTTCTTCACTCGACGGCG
+CTCTCCAAGATCTCCCTGTCATCGAACCCCTTGAGATGCGACTGCTCGGG
+AGGATCCCAACAGCACCTTCACCATCGTCGTGACCCAAAAGCTCATCCAT
+TCTGGGAGCATAATGCGGCCGAGTGGTTCTCGTTGCATCGGCATCTTGTC
+GTTGATTTCCCCAAGGTTGAATGCTGGGAGAACGTGACGAAGGCCTTCCT
+GACGAACGATACGACAGTGCTGAGCGCCTATCCACCTAATATGGGAAATG
+ACGTCTTTGTGATGCCTATTGAAGGTTGGTTTAAAATTTTTAAAAAAACG
+CGCGTCAAATATTTTAAAGTCTTTTGTTCGAAAAATAACCATTTTACAAT
+ATGTAGGATATATCTATAACAGCTACTGTAAAAACTCCAGATGTTTGAAT
+TTTTTTAAAAATGCGACGTGGTAAATATTATATTGATTACATATTATTAT
+TACAGTGTATTTTTTTCCACTTCTACGACTTTAAAGGGGGGCGCATTTAC
+GCGCGATGGTCCCAGCATTGGTCTCGCCACGCACCCCAAAAATCAATGGG
+TGGCGCGTGTCGAGACCATCGCGCGTAAATGCGCCCCCCTTTAAAGTCGT
+AGAAGTGGAAAAAAATTCACTGTATAATTATTAGTCAAATGATACTTATT
+ATGATATTAGAAATTAAAAAATTAGGTTTGAACATTTTTTTTCCTCGATT
+TTTTTACGGTATTTCACCATGTATGCGTTATAAATACAAATATGATCCCT
+ACCTTTTTATAACTTTAAAATAACTTTTAAAAAGGAATATAATACATGCA
+CAAGCACCATAAAATTTCAACGTTTGCTTTTTCTGGTCCGAAGAATTTTT
+TCAATACGTTTACTTTATATATCACATATACAAACAATATACTGAGAATG
+CGTATTGCGCATTATATTTGACGCGCAAAATATCTCGGAGCAAAAACTAC
+AGTAGTCCTATAAATTCCTACTGTACTGCTTGTGTCGATAGAATATTAAA
+ATTGCAAAAAAAATTTAAAAAAACGAAAAAAAAACAAAGTATAAGGGAAT
+ATATAGCTATTCCAAAATAAATCAATTTCAAAAATCGAGCCCGTAAAAGA
+GAAGGACTTACTGTAGTTTTCCCTACGAGATATTTTGCGCGTCAAATATG
+TTGTGAAATACGCATTCTGAAGATGTAGTGTACTCGTAATATATATTTTT
+TAACAATTCAAACATTTCCAGAATTCCTGCGCGACTACAACTCAACAATC
+TGTGTTCCATTCTCATCTGGATTCTTTGGACAAGACCCTCAGAATAGTAT
+ACTCTTTGTAATAATAACTATATCGATTGCTGTTCTCCTCTGTGTCCTCG
+TTATTCTCGCAATTTCATTTATTCGAAAATCTCACGACGCAATCAATCAA
+CGAAGATACAAAGCATCATCTCTAAATTGTTCAACATCAGCCGGCTCGTC
+GCCTCTTCCGGTTCCGCTGTTGAGTTATCACGCATTTGTGAGCTATTCGA
+AGAAGGACGAGAAAATGGTGATTGATCAATTGTGTCGACCGCTGGAAGAT
+GAAGATTATCAGTTGTGCCTGTTGCATCGGGATGGGCCGACTTATTGCTC
+GAATTTGCACGCGATATCTGATGAACTCATAGCTCAGATGGACTCGTCGC
+AATGCTTGATTCTTGTGTTGACTAAACACTTTTTGGAGAACGAGTGGAAA
+ACGCTGCAGATTAAGGTAACAAATTCAAACTTTCAGTTTAAAATTGATAT
+ATTCGTAAAAATAAGATGTTCTTAAAAATTCTGAGAATGCGTGTTGCGCA
+AAATATCTCGTAGCAAAAGCTACTGTAATTATTTTATATGACTATTGTAC
+CGTTCAAAATTACTATCCAAATATTTGATTTTTTGTTTTAAAAAATTATT
+TGGAATTTACTCAAATATTGAAAACAATATTATCGAAATTCCAGAAAATT
+TGGTGGAAATTCCGAAAATTTCAATTTTTTCGCTAATTTTCGAGAAAAAA
+AAAATTAAAATTTGGATTATATGAAATAAATTTCCAAACATTAAATTAAA
+AATTTTTTTTTTTTGGATTTTCCAATCTCGAACCTTCAAAAATTGAATTT
+TTTTGAAATTTTTTTTCGGAAAAAGTAAAAAATGCTCGAAATATCGACAA
+AAAGTTGAAGTATTTTTTTTTGTAAAATTGGAGATTTTTGAGATAAAAAA
+TCTGAATTTTCATTCAAATCTTGAACATCAAAATCAGCAAAAAAAATTGC
+TATAAATTTATTTAAATAAGATTTAAAAAGAGTAATTCGCTATGATTTCA
+AATTTTCAAAAAAAAAAATTTTTTTTTCAAGTTTTAATTTTTGAACACTA
+TCAAAAAATTTATTTTTAAACCAAAAAAATTCCGAATTTTCTGTAAAATC
+TCAAAAAAAAAACATTCCTAGAAATTTAATCGAATATGATTTAATAATAC
+TATTTTTAAATCATATTCAATTACATTTCTAGGAATTATTTTTGCTAGAT
+TTCAAAAAGTGTATGAAAAATTAAAACTTTTTGAAAAAAAAACTGTTCTA
+AATATAATTTATAACACCAGAAATTCACTAATAACACTCCACATTTTTCC
+AGACCTCCCACCAACTATTCGCCAAAAACCGTGCAAAACGAGTGATCGCC
+GTGCTCGGCGACGGTGTGGACGCGAATCTGCTGGACGATGAGCTCGGACA
+GATTCTACGGAAGCACACGAGAATCGAGATGCGGAGCCATTTATTCTGGA
+CACTTTTGCACTCATCACTTCCATCACGACTTCCATTACCATCGAATAGT
+GGCGATGATTCGTCTCAACTATATTCGGATATCTATGGAATTGTGCCTTC
+CGATGTTGTTTAGCTTACAGTTTTCCCGTTTAGGTCACAGTTTTTAGTAT
+TTTTTTTCCTCTTCCAAATGTACGAGTTTCCATTATTCACGAGGTTTCTT
+TTTCACCCCCAATTCTTCTGTGCACAATTTGCCATTTTTTGAATTTTTAC
+AACAATACCGGTACTATATTTTTCGATTTTCTTTCTTTTTCTATGAATCT
+TGCCATCATTCTCTAATAATTGACCAGCGATTATATTTTTGATTTAATAA
+TTGAATATTCTCGTTTTTCAGTTCAAATTATTGCTTTTTTCTGTCACCAC
+AAATTCAAATTCTCGTCCTACCCTGTGTGATCTTCTGTAATATATATATA
+TTAATAATCGTCGTTTCTTCTTGTTGTCATTTGCGGATGCTTATGAAGCT
+TGTATTTTAATTTTTTGTTTTGTTTTTTTTCCTGTTTCAGCTGCAAAAAA
+TTCGGTAGAAATTCTTGAAAACACGCAAAAAATGAATAAAAAAAATAGTA
+TATTAGCTTGTTCGAGAGGAGTTCACAAGCGGGTGGCCTAACATCTCCGC
+GGCCGCCCAGTGGTGTACTCCTCTCGGGTGAAAGAATTCCCATTTTATCA
+TCAGTTTTTCGGCCTATTTTTTCAGTTTTTCTCAACTAAATAGTCAATTA
+TCTCTTAAATAATGTCGAAATTAATTTAATTTACACATTTTTCCAATAAA
+ATTCCAATTTTCGGTCATTAAATTACCCCTTTCGAATTTTGCTCTCAAAA
+ATTAAATTTTCATCGATTTTTAATTCTCAAAATTCTTGAATTTTCAGCGA
+AGATGGGCAAATTCAGCAATCAGAAGAAAAATCGTGTCAAGAACAAGGTG
+GCGGTGACAGTAAAAAAAGCGCAACGCATGAAGGCAGACGCTAAAAATGC
+CAAAAAAGACGGTGAAGTGGATGTTGAGATGAAGGAGGAGGTGGTGAGAG
+TCAGAGGACTCGCCGTATCGTCGCTGGTGAGAAAAAAAAGGAAAAACTCG
+GCGAAATTCTTGATTTTGATTTTTTTTTTCAGAAAAAATTGGCCTCCGGT
+GAGCTGCAAAACGTGCCAAAAGTGAACGAGAAGAAGATTATCCGCAAGAC
+AGAGCTTCCAGTTCGAGAGAAGTAGGATTTTCTCGATCTCTCCAAACAAA
+AAAATTGTTTTTTTCAATTTCAGCAAAAAGATCCTGGACGCTCCGACTGG
+AAAACGTGGCACCACTGCTCAATACATCACAAAAAAGAAGGCAAAGAAGA
+TGTACAAGAAGATGACACACGACGCACGCGACAAATATCGAAAAATTCAG
+GCGGAACTGGCCGGAGACGGTGAAGATGACGAGGAGGGTGAAGCCGAGGT
+GATGGAGCAGTGATTTTGGATTTTTCCGCGGCATTTTTAAAATTGTTTTT
+TTTTGTTGATTTTGTTACTGTTTTTCATTTTCCACATAAAATAATCGAAA
+ATTTATTTATCACAAAAACTTTTGCACAATTTGCTCAGCTGAGTGAGCCA
+ACTGTTTGCCACGTGTCACGATTCGATGCATCCATCCATTGGGCTCCTCG
+AGCTCCGCTTTCGGAGCCTGTAGCTGCTTTAGAATTATTGTCCAGAGCTC
+AGAAATGTTCATCGAGTACTGCGCGGAAACTTCGACGAAATTGCACTTGT
+GTACTTTGGCCAGGCAGGCTCCTTCTGGAAAAATCAATTTAAAAATCGAT
+AATTTGAAGTTCCACGTGGAGCCGCGACGCGGCACGCGTTGCATCGTTTT
+TTTTGGTTGAAAAACATGGTGCATCGAAGAATTTTCCTTTGACGATTTTA
+TACGCAATGCATCACATTTGACGAACAAAAATTCAAAATACTTTACTTTG
+CAAACGCGCTCCATTGATAAACTTATGAAAAATCGATAATGCTCAAATTT
+CACAAAATTTTCCTCCATTTGAAATTATATAATTGTTAAACAAAATTAAT
+AAAACCAAACATTACGCGCAGTTTCCGATAAATTTCGATTTTTTCAAAAT
+GCAAGCGCGCTCCATTGCTAAACCTTGAAAAACCCACCCATTTTCGACAC
+CACCGTATTCCGTTTCAAATCGATTTTATTGCCAATCAGTATAATATTGG
+CTCCGCGAGCAATTTTTCGATTCAAAAGCCGACTGAGCAGGTCTGTGGCA
+CACACGAATGATTCTCGATTGTCAACGTTGTACACTATTGCGTACATTGT
+CAGTGATGACGCGAATGGAGAATTCTGGAAAAAAACAAGAGTTTAAAGGC
+GCAGGTGGGTCTCGCCACGATCCATGTTTTTTTGCGGGAATAGTGGAAAT
+TTGGAGTTAGTAAAAAAATCAAATTTGTGTAATTTTTAATAAAATCGGTT
+CGCAAATGCGCTAGTACATCAGATTTCACGAGCAAATTTCATTTTGTGAG
+ATTTGCACCAAAGATATGGGCATTTGAACTGATTTTTTAATGGTAAACAC
+GCGAAAAAAAATACATATCCAAAAATTGAAAAAATTTTAGGTTTCACAGT
+CTCCTCGGCATCGAAAGCGCAGTAGTAGGGGTGGCGATAGGGCGCCCTGC
+TAAATTTTCTATTTTTATGGTCTTTCTTTTCGTTTTGTGCTAATGAACAA
+AAGTTAAGTTCGAAATCTGCGAAAAAAATCGTTTCAACGCTAAGAAACGA
+AGAATTGTATTTCTCAACGGTAAAAAGATTCACTCCTGCGCCAAGGTGAC
+AGCAAGTGCGCCCCAGCCCAATTCGACGCTGAAGAGACTGTGGGTTTAAA
+AATTTAGAGAAGTCGCAAATTTTTTGTTCAAGATATCAGCCTAAGCTACG
+GTTTAAAGGCGCACAAGCACGTGGTGTCAAAGTGTCCCGTTTCGGTGTGA
+TCTACCAAAAATGCGGGAATTTAGACGCAGACTTCTCAGCAGATTTCGTA
+TGGTTAAGAGTGTGCTGACGTCACATTTTTTTCTGCAACAAATTCCCGCA
+TTTTTTGTAGATCACACCAAAATGGGACTGTTTGACAGCACGTGCACAAG
+CAGATCACAAGTGGGTCTTCGAGTTATCCTCCCCAAATCCTGTCCAGTAG
+AGCGCACTTACCTCCAACGTGGCTTCCAGCAACATTTCCAACTCGATTTG
+CTCGTTATTCAACAGGAAATTCATCGTTTTCGATGAAGTGTCATCTCCCT
+CATTTGACTCATTATTGTATTGGGTGACGAGCCGCGTGGCAAATTGGTTA
+ATTGCTGACAGCAATGTTTTCTTCCCGCTATTCCTTGATCCATAGACACG
+TAGAACCACATGTTGCATTGGAACATTCGACGTTTCTTGGAATAGCCAGA
+CTTCTGGACACGTGGCTCGGCGATCTTCTGAAAATTTTTAAATTTTCAAA
+AATTTGGTTAAAAATTTCAAAGGAAAATCAATAACAAAGCTACTCCAAAA
+TTTTCAGCCTGATTGGTTGGAAAATGAGCAAGTTACAGCGCTTCAAGAAT
+TCTAGGCCACGGTCACCAGGGAGTGGTGGCGGTGACCCTCTATTTCATTT
+TTAGATTTTTTAAATGGGAAACTCGAATTTAAATGTGAAACATCTGGAAC
+ATTCCAAGAAAAATTCAAAAAAACTCTCTAAGGAGTCGATAACCCTCCCC
+CAATTCCTGAGATGTGACGTCATCAGGGGGAGCCCGTGACCTCATAGCTT
+CAAATTTGAATTTTTCAACGAAAAGTGTGAAATTAGATGTAAAATTACTA
+GGAAATTAGAAGAAAGATTAGAAAAGAAATTTCGGGGGTGTCGCTCACCA
+CCCCCCCCCCCCATTTTTATAGTGTGACGTCATAGAAAGTGGGTCCCCGC
+TACCTTCCATTTTCAAAGTTTTTTTATTTTTCCGATGATTGTATTACTGT
+ACTCACTGTAATTATGTGCAACAACTGGTTGTCCAGTGGAGCACGTTTGC
+TTATACCCATTGTCCGTCACAAATCCATTCTTAATTCCAAAACTTCGAAG
+ACTTCCCTCCGGTCGTTTTTCGACGTCTTCGATGTTGTTTTGGTGCATTT
+GTAGAGAGTATTGGTATCTGGAATATTAAGGGGAAAATGGTGAAAAAATT
+CAGAAATGTACAGGTAATCGAGAAAAAAAGTTAAAACTTTTTTTGAACTA
+AATTTTTTTTTCAAAATTTCAAAAAAAAAATTTTATTTGAAGAACTTTTT
+TATAATGTTAATTTTTCTGAAATTACTTAACTTTTTCTCTCAAAACTTGC
+TCACTGAGTTTTTAAATAGATTTCTGAAATTGTCCACGTGAAGTACACTC
+CCAATATATCAAAGGAGCGCATTTGCGAACTAATTTTATTAAAAATTTCA
+CAAATTTATTTTTTTTAATAACCTAAAATTTCCGCTATTTTATCGTATTT
+TCTAAAATAAATAAAAAATTGTCCAGGAGGAGTACATGGCCAATTTATCA
+ATAGAGCTCATATGCACACTTGTTAAAAAACAAAAAAAAAACTTATTCAC
+CTTGGCGGTGGGTACCGCTTTTTCACACGACGAGGCGAGTTTTCCGAGCT
+GAAAAATGATACTTTTGGCTGGGAAGTTTTAGAATTTTGGGGAAAATAAG
+CATTTCCGGTGAAAAAAATTGTTTTTTATTGGAATAGTTTTTAATATTCT
+AGGCCATGTCGTAAAGAATTGAGTCAAAATTTAAATTTTTGAGGTACGAG
+CTTCCAGTTCCCCCCACAATTCCCCCTATGGCCTAGAATTTCAGAAAACT
+CTACCATCGATTCAAACTCTGTTACTTTTGAGGATAAGGGGTTCCGGACG
+CCCCAAACTTCCGCCCGTGGCCTAGAACTCCCAACTTCTTCCACCGACCT
+GGACGTGGTGCTCGTACTGGCAAAATGCTCATCAACATCTGGCAGTAAAT
+TGTTCAACCGTCTTGGGGACACGGTACGCGGGGTCGACGGTAGACTTCGG
+CGACTGATCGGCGATGTAGGAAGACTTCTGAAAAAAAATCAATCAATAAA
+ACAACGACACTCTGCTCGTGAGGATCCGCCCATTCCGCTTGTTGTTTACC
+AATTTCTTTTAAAAAAATTCTACAATGCGCAAAATTAATAGAACTACCTT
+CTTATAATTTTTTTTTAACTCAAAATTTTCAAAAAAACAACGACACTCCG
+CTTGTAGACTCCGCCCACTTTCCAAAAAGGACAATTCGGAGTGTCGTTTG
+AAAAATATCCTAAAATTTGAAAAATTCATTTTTAGTCTCAAATTTTAATG
+AAAATTACGTGAAAATCTATAACAACTACGACACTTTTGGCTCCGCCCAA
+AAACGTCTTTTGGCTCCGCCCGAAAACGGGGCGGAGCCTGGCACTAATAT
+TACAGTTTTTATTTCCATAAGTGATTAAAAAATCAACAAAAAAATTATTT
+AGAAAGTATCTCAATTATTGAATGAAATTTTATAAAATCTACGACACTCC
+GCTTGGAACCCCCTCCCCCTGCCAAGAATGGGGCGGAGCCTAGAACAAAC
+GGAGTTTTTGCAAGAAAAATATTGCTTGAAATTTTAAAGACATTAATAAA
+AATCCGAGTTTTTAGAAAAAATTGGGCCAAATCGAATAATAAAAAATACG
+TTACTCCGCTAATAAAACCAGCTCATTACCAAGAAAGGGGCGGAGCGTAT
+ACAAACGGAGCGTCGTTTGAAAAAATATTTTTTGGAAAACTAAAATGTTC
+CAGCGGGAGGAAGCTTCTGCAAAGGCAATCTAATTTTTTTCCGGAAATTC
+AATTTCCTCAGGGTTCTCTCTGCAAATTTGTTCACGAAAAAACTCGTGGT
+GCTGTGCAAATGCGCTCTATTGATAATTTCATCTAGAGAGCGCAATTACA
+TCAAATTAGCAATGGAGCGTTGTTGCATACCTTCTCGTTGCAGCGGGAGA
+CGCTGGTGACGGAGGTGATAGCCGTGATGAAAATTGTTGGGGTATCGCCA
+GCGCAACTGGAAGGGAAACACGACGATTCGACATTTTTCTGTAAAAAAAT
+CCATGATAAAACTAAAATTTAAAGAAAAAATAATGTAAATAAAAGTGGGG
+AAGTGGCTAAGCGGGGACACAAATACGCGGGAAATCCGCTTATTTTTGCT
+GGATTTGACGTAAAAATCCGAATCAACTGGCACTCGACGCGTTTTCCAAC
+AAGAAAAAACTAAAATTTCATATATTGGTGGCCTAGAAAATTCGAAAACT
+GTTCAAGCTTACGTAAAGTGTGTATTTTCCATATTAGAGAATAAGATTGG
+AAGAAAAATAAAATATTGTAATTTCTAGGCCACCGCAAAACTTCTAAGTC
+ACCTATGAAATTTCTAGGCTACCGTGAAAATTCTAGGCCATCATAAAAAT
+AAAATTTATATATTTTTGTCCTGAAACTAAGTCCACTTCCGCCAGAAATA
+ATAAAAGCAACAAAAAAGACAACACAAAAAATTGAGAACTCTTAAGAACA
+AAAGAAATCCGACCCGAAATCGAATACCCCACGAAAATTTTCGGAATTTA
+GAAAGAAAAACTATTTTTAGACACTTTTTTTCCTTCAAAAGGAGGAACTT
+TGTTGCGCGGCCTAAAAAATAGAAAACTCGGCCACCGATTTGTTTGCGGC
+CACGGGACACTCCGCAGTTGCAAAGGCTACAGATGCAAATACTGGAAAAC
+TAGGTCACCAAGTGGAAACCTTGGTCATCGCGTGGAAAAAAACTTTGACA
+AAAAATTTTTGAAAATTTTATAAATTTATTCTAGGCCACCACCTGTAAAC
+CTAGGTCACCATGTGGAAGGCTAGATCACCAAGTGGAGCCTAGACCAGCA
+CATAGGCCTCTAGGCCACCACGTAGGAAATTAGGTCACCAACTGGAAAGC
+TAGGCCTCCACATGATAAATAATATTTTTTGGAATTTCGTTTTGACCAAA
+GAAACTTGTTTTTACCAAAATATTTGAAAATCGTTTTCAAGGCCGTCCGG
+TGAAAACTGTGTAAACCTAGGCCACCAAATAGAAAGTCAGGCTGCGACAT
+CTAAACTTAGGCCACCAAGTAGAAAGCTAGGCCATCAAGTAAAAACCTAG
+ACCACTATGCCAAAATAGATGCCTTCTAAAAGTTTCAGGGAAAAAATGTT
+TTTCAACAAAAATTTTTAAAATCGTGGCCGAGTGGACTTTAATAAAATTT
+ACTTTTTCAGCCACGTGGCAGAGGGATATCGGAGCATCGTTTGAATTTTC
+TAATTTCTGAAAGAAAACCGGAACACATTGCAAAAATACGAAAAATATAA
+CTGAAGCTGACATATGAAATGAGTTCTATGCTCCCCGCCGCCTATTCTTC
+TCATTTTTCTGCTTATTTTTGTCGTTGGGGGGATGCTGGTATCATATTCT
+TCGTCCCCTCTTCTTTCATTGCCAGTCTATTCAGTATTATAATTAGCGTG
+TATTCCCTATTGGATTCTGCTCCCCGTCGTTTTTTTTTCTATGCGAAAAA
+AATAGAAAATACGAGGTGAACGGGAATTTTTATGAAAACGAACGAAGAAT
+TTGAGTTTTCTAGGCCACCAAATTGAAACATAGGCCAGCAAACGGATCTC
+TAGTAAAAACCTAAACCACAATACGAAAAACTAGGCCACCAACGAAAAAT
+GGGAGATTCCGCTTGTGTGTTCAAGCATTTTGTAAAATTCTAGATTGTTT
+TAAAAACTTAATTTTTCCAGTACAAAAATCGATTTAAAAACAATAAATAT
+GTCAAACTCGTGACGTTTGTCAATAGAGCGCGTTTGCATGTCAAACAAAA
+CATATTCGGTGTAGATTTACGGGGACACTTTACAAAACAAAAAACCTTCA
+CAAGGCTCCAAATAAGAGCTAGAAAATGGAACAAATTTCCGTTTTTTTTT
+TGTTGGTGAGTGTCTTGTGAGGAGGGGACCGCCCGTGTCTCTTCCAAAAA
+CATTATTAAATTAGTGTGACGTCATCACATTGAAAAACAACAAATATAGT
+TCGAGTTTTGAAGAAAAATTTCGGAATTTTTCTGGTGAAAAAATTTCAAA
+AATTTCAATTTTTTTTTAAATCTTAAAAAATTTTTTTATATATTTTTAAA
+TTCAATGTTTGATCTGAAAACCAAATTTTCACACAAAAAATCTGGTTTTT
+GACGTCTAAATTTGCTTTTTTTCACCCAATTACGAGGTTCTCCGTGGGAA
+GGTGTGTCTAGACACTTGAACTTTTGCTTTTTTATTTTTTTTCTAATTGA
+AAATGATTAAGCTAGATATATTTTCTCTCTTTTCTTAATCAGAATTGTTT
+TTGAAGATTTTAAATTTTTACACTCCCGTGCAGCAAATGCGCTCCGATGA
+GAAGTATGGAAAATTACAACTGGAGATTTTCAAAATGTTCAATTAAATTT
+TGCGTTTTTCTTTTAAAGGTTCAAGAGTCTAGAAAACTACGAAAAGGTGC
+TGTGACCTTATCGATGACGTCATCACAATTCTTGAAAAACTGGGAAAATG
+AGACGATGTGGAAAGAGGGGATTATTTATGCTTAAATAAACTTTTTGCAC
+TAATTAATTCATATAGTTGTAGTGCTTCTTTATATTTTAAGAGAAATTGC
+AAATTTTGCACCCAAAAAAGTAGACGGCCGAGTTATGGGAAAACTCTTCC
+ACGGACACAAGACGTGGAAAACTAAAAGTTTCCGTTGTTTTTTATACGCC
+CGCATGGCACATCCCCGCCCCAACAAAATTTTCAGGTTTTCAGGGTGAAA
+ACATTTTTTCAGCTGCTGGGCGGCTTCTCGTGCAGCTGGAAATGTATTTC
+CAGACGGGTTGGAACCGGGATTTGTCATTCAATTGTTGCAATTACGCTCT
+ACCGCTAAACCTCGTTTGGACTCCACGTGGACAACACGGTGCCTTATTGT
+AAATTTCTCTTCCATCTCCATAATTTCAGAACAAACCGTCGCTTTTATTC
+TCCATAATATTATAATTTTATTTAAAAAAATCTGGAAACATTTATCGATT
+TTTGTGAAAATCTATGTGAGATTATTGACAGAAATACAAGAAAATCGATG
+CAAACATGCTCTATTGCTAAATAGTTCGTGTACTCTACGTCGACGACACG
+ATTTCAAGAGTTTTTCGTTTTTTGAACAAATCATCTGTTATTATTGCAAA
+ATTCGGTACATTACTCAAAAAAAAACAATAATTGATAAACATGTAGAAAC
+ATACATGCAAACACGCTCCGATGCAAATTATTGATTCTCCAACTTTTATT
+GTTAAGTTATCTTGAAAAAAAAACTGATAAAACGAGAAGTCCTTGGTGGT
+ATCGGTCGCCTAGAAACAGATGAAAGAATGGAAAAACAAGTATTACGGGC
+GGCTCCGTTTCGTATTATGGGGGGTGGGCCGCAGATGATCCTTTAGAATA
+AGAAAAATGTCTAGTATTTTGTGATACTTGTGAAATATAACCCTAAACTT
+AAAAAATAAATTAGGGCTCAAAAATGGTATTTTTCTAATGTAAGCCTACA
+AGCACAAAGGTATTCAATTTTTTTTCAATAGCTAAAAAATTAATTTTTAA
+ATTGTGATATCATAATACTTACACAAGTACCAATTTTGTTTTAAACGATA
+GAATATTCCATAACTTTTGGGTAGGATTTTCTGCACTCGAAAAAAACGGG
+ATTTTCAACAAAAATAGTGGACTTTTTAAAAACAACGAAAAAGTTTTGCT
+TGGGACCAAGTCTAGCAGATTACAAAAACTGATTCTTCCAGTCAAAGATT
+TTATATATCACTTAACAATTGTTTTGCCTACCTAGCAAATTCCGAAGTCA
+GAAAAGTTGAATTTCCCTCCAACAATTTTTTTTCATAGTCAGCCAATTTG
+CATTTCCCGCGAAAAAATTTACGGATTCACCACAATGGGTCTCCCACCAA
+TAAAATTAATTATTCATTTATCTTCTTAAAAGGTCACACGAGATGCCAGC
+GACACAGGGCAAGTGCGACCACTATCCCGAAAAAGACACCGACAGAACCT
+AACGAAGGCTTCCAAAAATAGCATAGAAATACAAGAGACACAGAATATCC
+CATGATGTTCTGTCACTTTCAACATCATTCTGCCTTTTTTGTTCCCTTGT
+GTATGGTGACTATAATTTGATTGTTCTGAATAATCTGATGTCTACTTGTG
+TTGTGGACCACTATTGATTTTTGCTGCTTTGGTTAATTTGAGGTAATACT
+TTAACAAATTTGTTTTAAATATCATAGTCATTTTACAAATTTCAACAGTT
+TTCCTATTAATCCGCTAAACCGCAACTAAAAATGAAAAATTAAAACTTTT
+CTCAAAACTGTATGGGAAAGTTCAGTGACGGTTATGATAATTACAACATC
+GTTAATGCAAATTTAACAGGTTTCGCAAAATTATATTCAAAAAATTTTTT
+AAATCGTTTATTACGGTAACAAGAAATGTTGAGAATGCGTATTACACAAC
+ATATTTGACGGGCAAAATATCTCAGAGCGAAAACTACAGTAACTCTTTGA
+ATGAATTCTGTAGCGTTTGTATCGATTTACGGGCTCGATTTTCGAAATTA
+ATTTATATTTGTAAAGTGAAAGCTATATTCAATTTTTCTTCGATTATTTG
+TTGTTTTGTTTTATTGTGTTTTTGTTTTATTTTAATATATTTGTCACTTT
+TCAAATAGAAATTAATATCGAAAATCGAGCCCGTAAATGGACACAAACGC
+TACAGTAGTCATTCAAAGAGTTACTGTAGTTTTCGCTCTGAGATATTTTG
+CCCGTCAAATATGTTGTGCAATACGCATTCTCAACATTTCTTGTTACCGT
+GATAAACGATTTAAAATTTTTTTTAAAACTATTTTTTTAAGTAGAACAAA
+ATTCAGAAAACAACTCGATAAAAATGTCCTAGTCATCCGATTAAAATAAT
+TTTTTGAAATAAATAATATGAAAATTAAATTTTAAATATTAAAAATGTTA
+TTGTTGCTTTAAAAAACGTTATTGGACTTTTCAAGGCGGCAAAAAAATGA
+AAATAAAAATCGATTATTTTTTGAATTGTTGACTTTTCGGTTTTTAAATG
+TTGTTGAAAAGAAACGAATTGTATATACGAATTTCAATTAAAAAGTTTAA
+AATGTTTTTTAAAATGTTTTATTTTTTTCAGATAGATCAACTGAACTTCA
+TAACTTTAAAAAGCCAGTCTGGGATGTATCTATACCACTCTATCAGACTA
+CTCTTAGCACTAATCACAATGTACGACCCCGTGAGAGATTGTTGTCTGTA
+CTGGATACTACACGAGTGGTAGAATATAAAGAAGTGTGGTGACAAGTTTG
+GGATCTGAGTCCAGTAGAAAAAAATCATTCTACCGAAACTCGAAACTATG
+AGCGACTGGTCAAAACTATGCATTTGACGACGTCTACCTGTTTTAAGTTA
+TTGGTGGTGAGTGTGCCTTTGAAGAAGTCGCTCGAGCCTCGACCTTCTCC
+GACTGGCTTGAACTGAAAGATCCTCGGGAATCATTTTTAGAATTTAGAGG
+TGGAGTACCGTCTGTGGATTTTTTTTTGCTCGAAACGATAGAATACAGCC
+CCAATATTCCGAACAGGGGTGCGCGGCAATTGCCGTGTGGCAATAGAATT
+TTCGGCAATTTCGGCAATTGCGGCAACTTAGGCAATTGCCAAAATTGCCG
+AAAATTCACAAAACCGGCAATTGCCGAAATTGCCGATTGCCGGAAATCCG
+AATTGGAAATATAAATTTGATTTTTTTTTGTAGTTTTAAGAGCTTGAACA
+TGCATTTTACTAAACAATTTTCTCTTTTTAAGCTCAAAATGGTTTAATCC
+TTTGAAGATTGACCGTTTTCTTTTAGAAAATTACTGACAGAATATTAAAA
+AACAATGTGACATTTTTCAATTTTCGATATACATTTAGGTTTGAAAATTG
+CCGAAAATGCCCTGCAATCGGAATTTCGGCGATTTCGGCAATTGCCGAAA
+TTGCCGATTGCCGGAAATTTTGAAAACCGGCAATTGCCGAAATTGCCGCG
+CACCCCTGATACCGAATATAACTGTAAAAAATGTATTAATTTTTTTGTTG
+ATTTTTTGAAAATTTTCATAAAAGTAAAGAAAGGGCCAAATTATGTTTGA
+ACTACTAGTAGTCTGTGACTTCATTTTTGGCATTTTTCCGTTTTTCAGCA
+ATAATGATTGGTTTTCTTTGTTCTCTAATTTTAAACATATTTCTTCACAA
+ATGTCTCAAAAATTAACAACTTCAGTTTAAAGTAATAAAACAAAAAAAAA
+AGAAAAATAAAGAAAAACCAGTCAGTTTTTTCAAAAATAATTCAAAAATA
+ATTCGGTCCTTATTTTTTTTTTTTTGCAAAAAAAAACAAAACAAACTCCC
+CTATAAAAATTTTCCAAAAAAAAATTGGAAGGTTTTTTTTATTTCAGCCT
+ATTTTTGGAAGTTGTCGAACTCGATCAAAACATTTTTTCATTGGTTTAAG
+TTTTATTATGCTTGAAATATTCAAATTCCAACATACCAGGCATTGAAAAA
+TCAGTTTTCGTCGCTTTTTGACTCGAAATAAAAAAAACCAAAAATTTTTG
+AAAAGTTTTATTATGATAGAGTCATTCAATTATATTCCCAGTACTTTTAA
+ATAATCAAACAATTTTTTAGAATGGCTAGTTTCAAAATCGGCGGCTTTGT
+CGTTACATATGAAAACATGCACAACAATATGAAAAATAGGTATGTCTTCA
+AAAATATTAAAAACAATATTTTTTTAATTTTACAGATGTTAGCAGTTCGA
+CGAAGCAATGCAGGAACTACAGTTATACAATCAAATTCACGCTTTTTATA
+TATTAATTTTTAAAATCATAAAAATTACAATTTTCATCAACGTTGATCAG
+CTAGACGAATGCATTAAGAAAAGGGAAAACATAGGGCTTCCCAAAACGTC
+TGCCTCGCCCGCCTTGTGGCGACCTGCGCCTGCCTCGTGCAGGCCGCGTC
+TCCAGTCAGTGCAGTGCAGAAATTTTTATTTCAAAATTGTACAAAAACAT
+GGAAAAATAGAGAAGGATAATTTTTTAGGCCTCGGAAATCAATTTTAAGT
+CCTCTAGCTACAAAATGAACCATTTTAGAGGAGTTTCAAAATTGTGAATT
+TTTACAAAAATTACCCAATTTTGCCACTTTTTAATGGTTTTTGATGGGTT
+AAACCTAGATCTTCTGGATAATTCCGCATATATGAATTACCGTATTTCCT
+ATATTAGTTTTGCATGCAAGACTAATTTTCAATTGGTCTGTAGGGGTGCA
+AGACTAATAGAGACTGCAAGACTATTAGAGGCTGCAAGACTAATTTTCGA
+ATGCTATAAAACTCCGAAACGTGACCAATTTTTGATTGTAAACTCAACTT
+GATATCGTTTAAACAACAAAAAATACATCCTTTTCCAATATTTAATCAAT
+TATTTGAACGCTTTTAATCAAAAACTCGAGTTCAATTTGCCCAGAAATGG
+GCCAATTTATTAACGTTGCAGCATCTATGCAAGATATTGCTGGACTGGAA
+AAAAGTCGGGTGCAAGACTTTTAGAGACTGCAATACTAATAGAGGCTGCA
+AGACTAATTTTCGATTTGCCCGTAGGGGTGCAAGGCTAATAGGGATGCAA
+GACTATTAGAGGAAATACGGTACCTGTTTTTGACAAAATTAGACAACTTT
+TTATTTTTGCTCAATTTTTTTTCAGCCATCTAATTACTGTCCTTTTTTTT
+TGGACAATAAAAATAAATTTTCTAAAAGCGTTTGAAACCACTATATTTTG
+CAAAAGGACAATTTTTTAGGGATTGGAGATCAATTTTATGTCCTCTAGCT
+ACAAAATAAACAATTTTAGAGGAGTGTCAAAATTGTGAATTTTTACAAAA
+ATTGCCCAATTTCGCCACTTTTTATTTTGGTGGGTTATACCTAGATTTTT
+TAAATTCAGCATATATGAATTACCCGTTTTCAACAAAATTAGACAACTTT
+TGATTTTTGCCCAATTTTTTTTTCAGCCATCTAATGACTGTTCTTTTTTT
+GGGCAAAAAAAATAAATTTTTCTGCAAACGTACAAAACCATTAGAAATTG
+AAAAAAGGCAATTTTTTAGGGTTCCGATATCAATTTTGAGTCCTCTAACT
+TCAAAAATGACTATTTTAGAAGAGTTTCAAAATTGTGATTTTTCTGCCAT
+AAATTGCCCATTTTTGCCACTTTTAATGGTTTTTGGTGGGGTATACCTAG
+ATTTTCTGAATTCTGCATATATGAATTACCGTTTTCGACAAATTTAGACA
+ACTTTTTATTTAAAAAATTAAAAAGGATTAAAGGACGATCCGTTCTTCAA
+GTGCTATGCACTGCGGATCTGGGATTCAGGTACACTGCCTGGTGGTGATC
+CCTCTGGGCTGTAATTTAAGCCACGTCCTAGCCGAGGACTGTGGCCGATA
+ATCCAGTCGTGGATTGCTCCACTTCCCAATAGAGGCAGGGTGAACCTAGG
+GGGTGAGGCCGGACTTTTATCTCGTGACCTCCAGACTGCTAGCGGCCACC
+ACTACCGACTGAGCTATCTGCCCCCCTTGGGGAAAAAAATAATTTTTTTT
+TTTTTTGGGCAAAAAAATAATTTTTTGGAAATTGTACAAACCAAATATTA
+TATATTAAAAAATATTATCCAAATATTCCAAATATTCCAAATATTCCAAA
+TATTCCAAATTCCAAATATTCCAAATATTCCAAATTTATTCCAAATATTA
+TGAAAAAGGCCATTTTGTTAGGGCTGGGAAGTTTGAATTTTTACAAATAT
+TGCCCAATTTTGCCGCTTTTTAATGGTTTTTGATGGGTTAAACCTAGATT
+TTCTGAATTCTGCATGTATAACTTACTTGTTTTCAACTAATTCAGACAAC
+TTTTTATTGTTTTTTTTTCAAATTTTTTCAGCCAATTAATGACTGTCCTT
+TTTTGGGCAATTTTTTTTTTGAAACAAAAAAAAATTAAATTAAATTGCCC
+AATTTTGCCACTTTTTAATAGTTTTTGATGGGTCCCGGAAACCTAGGAAA
+CCTAGTCCCGGAAAATCGAAAAATCGAAAAAAAATTTTTTGAAAATTTAC
+CAATGAAAAAAAAAAGACTCAATTTTCTTCCAAAATAAAAAAGTGGGCAA
+AATTTTAAATATTTTTCGAAAAAAAAACATAACTTTTCAAAAAATTTTTC
+GATTTTCCAACAAAAAAGTGAAATAAGAAGACATGCAGGTTACTGTAGCT
+GATAAAGCTTCAAGCGTACCAGGACCCGAAAACCGCCGCCCGCGTAAATC
+GACATATTTAATGTACCATCAATTTGATCCTCCTCTTCCTCCTTCTTTCA
+ATGACACCACACAACTTCCTGTTATGAAGGTCTCAATTCCCCTTCATAAC
+ATTCTTTGTAATTAATGCACCCTAAACAAACTGTGCAAACACACTTAGAC
+ACCCCCCTCCTACACGGTCTTTGGAGTTCCCCCGCTCAACTCTAATGGAC
+CTGGTAATCCCTTGCGCGGTGGGATTTTTCGGGTCTCGCCGCGATTTTTA
+TCCGAATTCCGGAATACCGGAAATGGCGTGGAAATCGATATTGCAACAAA
+GAAAACTGTTTTATTTTCAAAAATCCGCTCACTTTTTTTAAAAGTGATCT
+TTCAATCATTTTTAAAGTTTTTTTTTTTGAAAGCACGCGTTTCTGGCTTC
+CCACATATTTTGGAATGTAAGAGATTGCCGAGTTAGGCCATTTGGACTCG
+GCCACGGCCGGGGTCGATTCACGTAGCGGCTCGGTTTCTGTAGAAAACTA
+AATGTATTTGTCCGTATGGAGTACACAAGCTTTTCCAGGCGTTATCCGGC
+AGGCGATAGAAGCCGCGACGCAACACGCAACGCGCCGTAAGTCTACCCCG
+GCCGTGGCTGAGTTATGATGGCCTAACTCGGCAAACTCTTGCATTTGAAA
+ATATGAGCGAAGCCAGAAGCAGGTGAACATGGATTTCTGGCTTCCCTCAT
+AAATTGAAAAGGGAGAGTTTACCGAACTAGGCCATTTTGGCTCGGCCATA
+TCTGGGGCAGATTTACGGCGCGTTGCGTGTCGCGTCGCGGCTCGTTTTTA
+GTTGTAAAACTGAATGTATTTGTCCGTGTGGAGCACACGACTTCCCCACG
+CGTTGTCCGCTAGGCAATTGTTAATGGAGCGCGAAAAATTCAATGAGGAA
+GGCCAGAACCCCGTGTGTGATTTTTGCAACTACAGCCCAAAATTTGAACG
+GGATTAATACAAATTTAATTTGAAATTTGGATTTCGCAATTCAAAATTTG
+CGAAATTAAAATTTCGAAAACCCGAATCTCATCGAAATTAAATTCCAAAG
+TTTTCATTCAAATTTCAATGAGGTCTCTATTGAGCCGAATTCCCGCGCAC
+GGGAGGTAGTGGACCCCTTTTGTATGTTTAGGGGTACAAAGACCCCCTAC
+CACCCCTTGTATATGCACAATAGAGAACACTCAAGACCCGCCCACCCTAG
+GCCCCTCATCCAAAACATATCCGAATATACCCTCTACTGTACTTTATTTA
+CTTGCTCCGTTTACCCGGGTACCAGGGTACTCCCTAAACTAACTGAATTT
+CCAAGGTGGTGGCCTAGAAAAAGCTCTTCCACTGGTTTTTTTGTGGAAAG
+AAATGATGAAGGTTCTTGTTGTTTTATTGCTTATGGTAGGTTTTTTTTGC
+CACGTGTCCGGAATTTTTAAAACTATTTTTCTATTTTTTAAAGGCCCAAA
+ACTTTGTTTTTTTTAATGTTATCGTTTTTTCGTGAAAAAAATTATTTCAG
+AAAACGGGGGTTTTAGGTTTAGGCTAAAGCGTAGGCTTAGGTTTAGGCCT
+AGGCTTAGGCTTAGGCTAAGGCTTAGGCTTAGGCGTAGGCTTAGGCATAG
+GCGTAGGCTTTAGGTTTAGGCTAAAGCGTAGGCTTAGGTTTAGGCCTAGG
+CTTAGGCTTAGGCTAAGGCTTAGGCTTAGGCGTAGGCTTAGGCGTAGGCG
+TAGGCTTAGGCCTAGGTGTAGACTTCGGCTCAAACATAAGCTCAGGGGCA
+AAAAAAGGAGAAACTCCCACAAATTCCTAAAAATCCTGAAAATTTTTTTA
+AATCTTAAAATAGTCAATTTTCAGTGGAAATCACAGTGAGCATTTTGAAA
+ATCCAATAATTTTCAGGTAAATTCGACATTTTCGTTCGGATTGGACAATG
+AAATAATCGGTGAACCAAAGTTACAATGCAATCCGGAAAGTATTACATTC
+TCCTTCAACACACGGAATCCGTTTATGTTAGTCTTGGGGTCTCGACACGA
+ATTTTTCCCGCAAAATTAGTTTTCCACGCGTGAGTACACCGCAAGTAGAG
+CGCTTATCAATAAATTATAAATTATCAATAGAGCGCACTTGCCCCCGGTG
+AATTTCAAAATTTTCAGAGGAAACGTATATATTCGTGGCTTCTACCGAAC
+ACCCGGCTGTCGTCGGCAATTCCTCGCACCGAATCAGGCTGGCGGCTCAT
+TTACGGTACGGCTCGGCGATTGCGGGATGCGGCGGTCCCGACAAATCAGT
+GGACATTCGCCACGTGGCGTCAATCAGCACATCACTTTTGTTGCGAACTT
+TCATCCGAATCTCGCGACGAAAGAGGAACGATCATTCAATATTCGATGCT
+TTTATGCGCACAGTGAATCTGTTGTCAAAGCTGATCTGGATGTCAGGTAG
+GGATGCAAATCGATAAATTCCCCGAAAATCGATACATTTTCCAAAAATCA
+ATAAATACCCAAAAAATCAAACAATTCCCAGGAAACTGGAAGAAAATTCT
+CAGAAAATCAATAAATGTATTTGTTTTGCAGCTCAATGCCGGAGGAATCG
+TTCGAACAGGGTGTGACAATCGTGCCCCAATGCACATATTCCCTTCGTGA
+AGGGACATTTGAGGGCCCAAAAGTGTCGAATACACGTGTCGGAATGACAA
+TTGTTCATCGATGGGACTGTGATACATCGGGGAACTATGGAATACTGCTA
+CGTGGATGCACCATACTCGATTCACGTGGTGTTGAATCTTTTCCATTGCT
+TGATGAGAATGGGTAAGAGTAGGGAAGTGTCGGCCGCTAGAAAAGAAAAA
+TATATCACTAGAGCACGTTTTCTAAGCATTTTTCTCAATAGAGCGCGCTT
+GCTCAATTCCCTAAAATAAATTATGGTGCATCGAAACGTGTTTACGTACT
+GATAGAGCTGTAGTACTCGAGGAAGCTGAAAAAAATAATGAAGAAAGTGA
+AAAAAATCAAAAGTGTGAACACAGCAGCCTTGTCAGATAAATTTCAAAAA
+TCTGTGCATTTGGTCGTAAGTTATGGCGCATCAAAAGTTTTTTGAAATTC
+TCAATAGAGCACATTTCAAAAAAGAGCGATTTTCGCAAAGCCCCTTTCTT
+CGTTGTTTGATTTAAAAACAATGCAATTTCGTTTATTTCGCAAATTTTTG
+AAAAATGAGTTAAATTTGCAACAGAGCGCGATTGCACACACACACACACA
+CACATCAAACGTCAGAGACCCCACTGATTTTGGAGATTAAATTACGGTAG
+ATAGAGAATCACAAGGAAAACATCACGAACTTTGTTCCGTCAATTCCCGT
+GGTGCTTGTTATCATCAGAATGCAAAATTTGAAAGTCTGAAATTAAGCCG
+TTTCCGCTAAAACGTAGCGAATCTCATTCCACCGAGTCTATTTTCGTGAG
+GTCTCCAATTTTTCAAGTCTCTGCTCGTTATGGTGCATCGAAGGGTAATT
+CAAAATTTCAAATAATTTTTAGACACTTTTCGACCAGTTTCAAATTTTTT
+TTATGGTGCATCGAAAGAATTTTGCGTAATTTTCAATAGAGCGCGATTAC
+TACTCACCTCTAAATTTCTGCAAATTCTTTTTCCAGATGCTCAGTGTCCC
+GTGACTTCCCACAAGTGGTATATCTCCCATCACTGACGTCAGCCTACATG
+GCAATCGAAGCCATCTCATTTCCTGACCAACCATCGATTTCTTTCTCGTG
+TCAAATTAAGTTGTGTGATAAGGGAAGTGATGAGTGTCGGGGTATGAGTC
+CCCCCGCGTGTACCCCATTGACACAGGTCCCCATCACGGGACAAGTACCA
+ATGCCATTTGATAATACAATTGGAAATACGTTTGGTGAGTTATTTACGGC
+CGAGAAAACCTGCAAAAATAAAAGTTCAGCCACCGAACTTTTTGACATTT
+TTGCGCAACTGTATGCCGCACAAAACTTTACGTCAGAAGTGGGCGTGTCC
+GCCTGCAGGCCCCGATGTTTTAGATGTAAAAAATTAGATGTTTTAGATGT
+AAAAAATTGAAATTTGAATACAAAAAAAAATTCGGCCACCGATTTTTTTT
+GCTTTCACGTTTTGTCAATGCATTTCCAATTTTTTTCGTGAAACGTTTTT
+GTCAGAATTGGGCGTGTCTTGTAAAGTCCCGCCCAATTTATGGGCGTGGC
+TTGTTTCGACCAAAAATACTGTTTTTTTAACTCACAAAAACAGAGCTATA
+AACTTTTTGAAAAAAACATCCCTGTCCTCTCCTTTCTCCATTCTAAAATT
+TGAATTAGATGGCCGTGAAAAACCCCGGCCGCGGTCTTCAATTACAGTGA
+AGAATTTGGCGGCAGAGCGCGTTTTCACAGTCTTTTTTTGTCGTCACTGA
+GCAAACTTCAACTGCTTCCAGCCAGAAATTTACAAGCAAATTCAAATTTT
+CAGACGGAATCCCACTGGAGCCGTGGATGAAAGAGCCCTCTCCTCCCACT
+GATGACGTGGCAAACATCACCTCAGAAGGCGAGCCAATGCCTCGGCTCAT
+CACCGAAGAGGAACAATATCAAATCGAGTCGAACCATGTTGAGGCGCGAG
+AAAAACGATTTGCTCATCGATTATTCAATATCACATCGGAAGATCTCTAT
+GTTGAGCCAACCGTCGAGCCAATGGAAGTAGAGATGCCTGGAGCACCGAG
+AGAAACTGCTCGGAGGGTGTCTGAGCCATGTGTCTCGGTTGAAACTTTCT
+ATATTTCGGCGCTTGCTGTACTTTTCGTTTTTGTCGTTTCGATTGGGATG
+GTCTGTTTCTTCGGAAGTCATATGCTTAAAAAGTTGGTTTTTTATTGATT
+TTCCTCCCACAGGGTTCTGACCTTCCTCATTGATTTTTTTGCGCTCCATT
+GACAATCGCTTGTCGGAAAACGCATGGGAAAGTCGTGTACACGGACAAAT
+ACATTTGGTTTTACAACTAAAATCGAGCCGCGCCGCAACACGCAACGCGC
+CGTAAACCTACCCCAGCTATGGCCGAGTCAAAATGGCCTAGTTCGGCAAG
+CTCTTTCATTTCAAAATATGAGGGAAGCCAGAAATCCATTTCCCCAAATT
+GCAAGATATTTGTGGCGTGGCCGAAGTTTTCTAGTTTCTCGGCCACGTTG
+TCAAAATTATTTTAAAAAATCGCTGGAAACACTAAATTTAGATATCTCCT
+GTAGATTGTGATTCGCGGAAAAATTCCATGAATCTCGTTCTCCCAGTTTT
+TTTTTTGTAAATTCAACAAATCAAATGAGCGCCAAAACCTCACAAATCTC
+ATACTCCCAAAATTTGCGTTCCTCTTTTTCTTGAGGCCTCCTCTTTTCAC
+TGTAAAATTTAAAAAACTCGTAACTTTTTCTTCAGAGCGCGATTGTACGC
+ACAGAAAGTCTTTAAAGTCTGAAAATATTTTAAAGTTCCCCAAAATCCCA
+CAAGTCTCATTCCACCGAGAGGTCATTTTCCGTGAGGTCTCTTTCTTGGG
+TCTCGACGCGAAAATACTGTAATTTTATTAATTTTTTCAGAACTCAAGAC
+TGTGAAATGCCGATTCCAGTCCCAGAAGGATATTATCTAAGCAAACACTG
+AAACTCTTGTTTAAAAGTATTCGTTTCCCATCCACGTGCCATAATTCTTG
+CATTTTCTTTTTTTTTCCCTATTTTTATTCAATTTATTTACAATTTGTTC
+AATAAATAATCAATAAATAATAATTAAAAATAACATTAAAAGTCACATTT
+TCCGAAGGAACCACGCGTGGAATGTAACGGTGCCGTTGTCGAATGGTTCC
+GGCTGAAAATTGATTAGTTATCATTGGAGCGCAATTGCATTTTTCTCGAA
+AAATCGATGTTTTCGTGTGATGCAGAATTATCGATTTTTTTTAACTTGGT
+GGCCGAGAAAATGGAAAACTCAGTCATCGACTTTTATTTACCTGGAACGA
+AAAAATTTAAAGTATGATCACGCGCTAAAGCCTCAATTATGCAAAATGCT
+TTAAAAACGGGTTTTGGAATTTTCTAGACCACTGGTGACGTCACTCCTTT
+TCCATTTATTATTCTAACTGTTTTCTAGGCCACTGATGTCGATATTTTTC
+CACTGCTGGGTTTCTAGATCGCCTGCGACGTCATTTCTCTTCCATACCCT
+GCTCTAGCGGGTTTCTAGGCCACTGGAGAAATTATTTTTCTTCCAAAAAA
+AAATCTAGGCCATTAATGACGTCATCATTTTTTCTTTTCTTTAGGATTAC
+CTCAGGTTCCTCATATTTCAGATCCATCCTCGCCAATCGTTCATTCTCAT
+GAACTTTTTCCACTTTTTCACTGCTCGTACTCTTCTCATCTACTGTATCC
+GCCACCACAACGTCCGGAGCAACAACTTGCTCATCAATATGCTGATATTC
+GGGCTCCTGGCGGTCCCAACGTGGTGTCTCTGGTGCAGTTTCATATTGAT
+TTTGCTGCTTCTCCAGGAGGTTCTGTATTGAACTGATCGCTGAGGAGGAT
+CCAACGATCGGAGGCATCGGAGGCGGCAGAGGAGCCATAGATGGAGTCTG
+AGAAGCCATCATTTGGAGTTGGGGGTAATTCCTTTGTTGGGACATCTGTG
+GGGACATTTGTGGGGACATTTGAGGGGACGGGGACATTTGGAATACCATC
+GGAGGCATTGGAGGTGGTGGGGGTGCCGGAGCCATTCGTATCATTGGAGC
+CATCACGTAAGATGGTGGAGATGGTGGGAGACTGGAATTTTTTTTTTGAA
+TTTTTTTTCATAACACGGGCTTCTGGCCTTCCTCATTGCACTTTTCGCGC
+TCCGATGATAATCGCCTGCCGGACGACGCGTGGAAAAGTGGTGTACTCCC
+CACGGACAAATACATTTAGTTTTCAACTGAAAACCGAGCCGCGACGCGAC
+ACGCTACGCTCCGTAAATGGCCTAATTTCTTTTTTTTAATCTTGAGTTAA
+AGTTTAATTTTAATTATTTCTACAGAATTGAATGGCTGGGAATGTGCCAC
+GTGGCCGAGAATTCTCCTGCGTGGCCTAGAAAATTCAAAAAAATATTTTT
+TGGTGGTTTTGATTACAAAATAAAGGATTTATACGGATAAAAACCTATTT
+TAAAAGCCGTGAAAAAAATCATATCAACCACTGCCTAAAAGATTGAAATT
+TTTATGATGGCCGAGAATTCTCAAGTGTGGCCTAGGAAAAATCAAGGCTT
+TTGAAAATTTGCTCATTTCGAAAATTAAAAAAAACAACTCAATTGATAGT
+AAATTTTAAAATTAAAAATTATTTTTCTGGTTTTTTTTTCTCAATTTTTG
+CAAAATCAAAATTATAATCAATTTTTAATCCAGAATTCGTCAAGTGGCCT
+AGAATTCTACTGCGTGGCCTAGAAAATTCCACCAAAATTTAAATTTTCCA
+AATTGTAAAAATGCTCCAAAAAGTTGAATGGTGGCCGAGGTTTTTCGTTT
+TTCACTTTTCACAGCTACGGAAAAAAACTCGGCCACCAATAGTTTTTCCT
+AGGCCATGTTTCAAATGCCCTATTTCTATGTTAATTACAGTATTTTCTAG
+ACAAGATTTTAAAAAAACTCACGAATAGCACATGGAGCTCTGACACTTGC
+TCCCACCAATACAAAATTCCGAATTTTTTACAAAAAACTGCAAAACTATA
+AGAATTTGTGGTAGAAATTGGGGCATTTACGTAATAATAATAATAGAAAA
+ATGTCCGCAAATTTTTTTTCATAAATTTCATAGGGAGGAGGTAAGCTTCA
+GCTAGAAGCCATTCAATTTTATTGGGGCGCCGAAAATCTTCGGAACACTT
+TTACAATTTATACAGTAGTGTACAACTTTTACAACTTAATAATATCTTCA
+ATACTTCCAGAATATTCTTCTTTTTCCTCCTCAATTGCCACGTCATCATC
+TTGTAATCTGGTCCATTTTGCTGGCGAGGCGTCGGCAAACAGGCAGAATA
+TAGTATTTACGAAGAGAAGTAAGCCCGCATGCGCCAGGAAACAATTACGC
+CAGTCTGTGAATCTGAAAAAAATAATCTTGTCTTTTAGGGGACCTACGCC
+TGCCTGCCTACGTCTGCCTTGCAGGGGACCTTTGCCTACCTACTTGACTA
+CCTTCAAGTGAGACCTATGCTGGTTTGCCTGCATTTTTGTCAGTGCCTTC
+TAGGCCTATGCCTACCTTACAAACTATGTAGGTCAACTGCCTGCTTTCAA
+GGTGGCCTAGGTCAGCCTACATGCTATCTACGTCTACCCCAATGTACCCT
+GTGCCTATCTACCTGCTTTTAATGCTATCTGCCTTTTCGATAGTCTTTTA
+GGGAATCTACGCCGGTCCAGCTCACATAGGTTATCTATGCCTATGCCTTC
+CTGCCTGCCTCCAAAGTGACCTACGCTTACCGTGTTTTTTTTTCTAGACC
+GTATATACCTACATGCCTGCCTTTAAGTTTACCTATGCCTGCCTGCATTC
+CTCATGCCTGCGTGCCTACATGAATACCCTAAAAACTCACGTATCATCAG
+TAACAATCATATTGACGAAAAACGGTTCGATGAATATCGTGCAAGCCCAG
+ATGTTCATGATCTGGAAGAGAAATCGTTGGCCTAAAAATTTTCTCGGCCA
+CCCCCTTACCTGCTGCATTGCGAAATAGGCGTACTGCTGGGAGTGCAACG
+TGGCACACTTGTTGAATCCCGCCGTATTGCACCCCATCACACTTTCGGCG
+CAAATCTGGAATGATGGAAGAGAATAGGAAAACTAGGCCATGGATGTATG
+TGCGCTATGTTGATAATCGGTTATTTTCAACGTGGATTATCAATTGAGCG
+CACTTGTCCCACTGGAAGAGTTTTCCTATCTAGGCCACCACCACCACCCA
+CTCACCATTATAATAATAGCCAGCAAGTGTTTTTCCTGTGGAATAAATGC
+TAGAACGATGAAAAAAACGGCGGCCACGGCCAGAGCGATTGTGTTGAAAA
+TTTTAGTTTTCAGAGTTTCTGAGATGAATCTGGAATATTGATTTTTGGTG
+GCCGTAGAGAGGAAAAACTCGGCCACTGATTTTTTTCACAATTATAAAAT
+TATTTTTCCAGGAAAAACCCCCGAAAAACTCACTTAATATAATCACTAAT
+AATTCCCGACGATAATTTCGTAAAAAATTGAAAAATAATGGGTAAGGCGG
+CCAAAAAACCGGACGAAAGTACGTCATAGTTCAAATAATTTTTCATATAT
+TGCGGATTGAATTGGGATACCAATTGAACTGTTATCAAATCTCCAAACGA
+TGCGATCCAACAAGCCCACAGGCTTAAACTTGTCAGAATATGACGGAATG
+GAAGATTTTTTGGCCGGGATACCTGCAAAACGAAAAAGTAACGGGCTTCG
+AATTTCCCCCCCCATGTTTTCAAATGGAAGAGGTGGCCGTGAATAAAGCT
+AACCTCGACCGGGGGTCGCGACTCGCGACAAACGGGAAAACTCAAAGAAA
+TTTCGTACTGTCGCTACTTTTTTTGAGTTTTCCTGTTTGTCGCAGGTCGC
+GACCCCCGGTCGAGGTTCGCTTTTTTCACGGCCACCTCTTCCATTTGAAA
+ACATGGGGGAAATTCGAAGCCCGTGAAAAGTTAGGCCATGCAATGCGATG
+TGGTGGCCGAGGTTTTGAAAACTCGGTTACTCTCATGTAAAAAATCTTGA
+AGTTGAAGCAAATTTGCGTACATGAAACCCATTTACCTTGCTAGCAGTTT
+TAGAAAAATTTGGGATTTTCTCATACTAATGAGGGAACGTCTTAATTGTC
+GACAAATTGCGTACCCCGAGGAACCCACTAATTCAGTCCTAGGTTTAGGC
+ATAGGCTAAGGCATAGGCTTAGGCGTAGGCCTAGGCTTAGGCTTAGGCTT
+ACACGTGGTGTCAGAGTGCCTCATTTCGGCTTGATCTACGTAGATCTACA
+AAAAATGCGGGGGAAGAGCCGCAGAGTTTTCTACTGATTTCGCATGGTTA
+AGAGTGTGCTGACGTCACATTTTTTGGGGCAAAAATTCCCGCATTTTTGG
+TAGATCAAACCGTAATAGCACAGCCAGGCACCACGTGCGCTTAGGCTTGG
+GCTTTCCGTAGTCCTTCGGGCGCGTTTTTCTCAAAAATGATACGTGGTAC
+AATTTCAGGTTTTTTTCCGCTCCAAAATCTAGTTATAATTTGTGTCCGGT
+AGAGCGCGTTTGCACTCACTTTCTTTCCCGATTTCCCTTCTCGAATCCTC
+TCCAATTCCTTCTCGCCAACCCAACTGTGCTCACTCGGCGAGCACTTGAA
+AAATAGGAAAAACAGCGAAAAAGTGACCAACGATACACCGGCGTGCACAT
+AGTAAACCGACGTCCATCCACCAGACGAAGAGCATAACCATCCCGAAACT
+GGCATTGTAAATATATTTGAAAGTTGTGTATTTCCGGTTAATAGGCCAAT
+GAATACTCCGTGCTCGTATGGGGTCGCCCAATTTGCTGTAATTGAGCCAG
+CGAGGGGAAATGTGGCTGAAAATGCCATTCCTTGACAAATACGGGCGGCC
+ACAAACCATCCGTAGCCAATGGTACTTGCCAACGGGATAAGGGCTGTTGA
+AACTGGAAAAATTGAGTGCAATACATCATATTTGACGCGCAATTTTAAAA
+TTTAAAAAATGGAAACGCGCTCTAATGATGCTTGGTGTACTCCTCTCGGA
+CAATAAATGTCAATAATTTTTGAAAAATCGATAATTTTTTTTTAATTTCA
+GAAAAATTCGTGAAATCTGTTTTATTTTGCGCGTAAAATATGATTCTTAA
+ATACTTAATTCAGTATTTTACGCACGTGGTATCAGAGTGTCTCATTTAGG
+CTTGATCTACGTAGATCTACAAAAAATGCGGGAGAAGAGACGCAGAGTTC
+TCAACTGATTTCGTATGGTTAAGAACGTGCTGACGTCACATATTTTCGGG
+CAAATAATTCCCGCATTTTTTGTAGATCAAACCGTGATGGGACAGCCTGA
+CACCACGTGCTTACGCGGAATTTTTCACAATTTTTTGTGCTTCATGCACC
+ATGTTTTTGTTTCGAAAAATCAGATTATTGTTTTGCGCGTCAAATTCAAC
+GCCCACTGTGCAATACACCATATTTGACGATCAATTTCAAAAATTTTGTA
+TGCTTTCGATGCATGCTTTTTGGGGTACTGTAGCTTTGAAAATACGCATG
+CACTGGATCTGACGACAAAATGCACAGTTTTTATAAAATTAGTCTATAGA
+AATTAGTCAGTTTTCTCGAAACAAATAAAAACTACAGAAAACTCGGCCAC
+CGATATTTTTTTTTTTCGCGGCCACGATTGACGTCATACCTCCCGAAATA
+ATTCCGGCGACAATGAAGACAGGTTTATGCGGCAAATGTTGAAAAGAAAT
+GGAAAATGGAATCGAGGCGGCAAGACTTCCAATAGCCACACACGATTGAA
+GAAAATTCGACTCTGATTTGGTATAGTTCACTGAAAAAATCAACTATTTT
+GGCGGCCGCCAATGGAAAAACTCGGCCACCGAATTAAAAAAAAAACCTTT
+TGAAGTTGAAGTACTATTATCATCTTGCATACAAATTTTTGTAAAATTAT
+AAGTATTCATATTTGAAAGAATCGAGGTCAAACACAGTGTGGCACATATT
+AAAATCTGCAAAAAAATCGTGAAAATTCAATTTTCCGGGGGTTTTGAGTT
+CAAAAAGTACCAGAAATCGGACAGGAACCGGCGAGTTGACCATGGTGCAT
+CAGAAACCGGAATTTTAAATAAGTAAAAAAATTTATGATGCTCGTGGTGA
+TAACGAAAAGTGCAGTGATCAATTTAAGGGAAATACTGCTGGGGGATTAA
+ACGTTGACACTGTCAACTTGATAGTGTTAATTTGATCAATGCTTTGTACT
+TGTTTTTTGCAGGAAAAATTCTTTGAAAATTGCAAGACTATAGTATAGTC
+TGAAAATTTGATGAAATCTAAAACTTTAATAAATACCGTTAATTATCATT
+ATTTTTATGAAATTTTAATATAATCTACTTAAAATTTAATTTTCTAGGCA
+TCTGTGAGCTTAAATTTTCGATTATCCCTCGCCAAATTAAAGATTTGCAG
+ACTTTTAAGCTTATAAGCTTATTTCAGTGAGAGAGAGCATTGTGAGAAGA
+GAAACGCAGACGAGGCTGGCGCGTTTCTCGTGCTCTGACGCGAGTCTCGA
+TTTGCTTGCGCATTTCTCGTGCGCGCGACGTTCATTTTATTTTTCCGATT
+TTTTTTCAGTTTTTCTGAACTTTTCTTCTTGAATTTGTGATTTTTTATTT
+ATTTTTCACGTCTTGTTGCAAAATAACTGATTTTTCACACAAAATATTCG
+AATTTTCAGGTCGGCAACATGGGATTCTTGTGGAAAACTGCAAAACTCGG
+AATTAAAGTTGGACTCGTCGCCGGCGCCGTCAAACTGTCAATCGATAACG
+ATATTTGGTCGACTAACAATGTTAAAGTATTAGTTTTCCCCCGTTTTTCC
+ACGAAAATTTTCATTTTCAGGGCAGCGAACTGTATCAAAAGCTTAAAAAG
+TACATTCTTCCCGGCACCGTCGTCTTTCCAGAGCAGGTTTTATCGATTTT
+TTCTCTGAAAATGCAATTTTTTTCTTATTTTCAGCTCCCAACAGTCGAAG
+ATGTGCAGCTGAAGGCCGGTGGAAAGTGGAACAGTGCTGTTGACTCGGTA
+GGCTGCATTTTTGAGAGGAAACACGGAAAAATTGCTGCGAAAGTTGGAAA
+AAAGTCCTGGAAAATGGAGATTTGGCGCCGAACGTTCAAGAAATTCCATA
+ATTTCAAAAATCTATCTGAAAAATTGAAAAATATAAATTTTCAGTCATTT
+TTAGTCAAATTTCAGAGCTAAACGTCGAAAAAAGTGCCTAAAACTAGGAA
+AAATATGACAAAAAGACACAAATTTTGGAGAAAATTGCTGAAAATAATGC
+AAAACACTTTTTTTCACAAAAAGCGAAATTCAAAAAAAATTCCACGTCAA
+AAATTAACCAAATGCAAGTACGCTCCATCGCACTTTTTTCCAATTTCTGA
+CTCGAAAAGTCTTAAACTTCTGGTTTTGTAGGAAAGATAATGCAAAACGC
+AATTTTTAGTCCAAAATTCAGAGAAAATTCTGAAATTGTTTTTAAAAAAA
+ATGCAAGCACACTCCATGGCACTTTTTTTTCAAAATTTCGCGTAGAAAAT
+TACAGACATTAGCAAAATTCCGACGATTTCGCTGCGAGACCAGAAATATT
+GTAGGAAATTCAAACATTATCCGAAAATAATGCAAACGCGCTCTATCGCA
+CTTTTCTCCAAGTTCCCACTCAAAAAGCATAGAAAATACCTGAAATTGCC
+GTTTTTTTTCACCGGAATTTCAAATTTACGCGATTTCGCTGCGAGACCCA
+AGCTAGTGCAGTGGAGCGCATTTCCAACAATTTCAAACTCAATTTTTTTC
+AGGTATTCACCACAATCGAGAACGTCCCATCAAGCGTGAACACAGTGGCC
+AATCGACTCATCAATAATAAATAAATTCCCCATAAAAATTATCGATTTAT
+CGATTTTCCCCCCGAATCCTCGTGTATTCCTTCGTTAGAATGTACTTTTT
+CCCTCCTCATTTTCTAGAAGTATTTGTGTGTGTGCTCTATGAAAAAATTT
+GCAATTTTTGACTTTAAACGGACGGTGCATTATATTATTTTATCAGTTCC
+CATCGTTGATCAATTTTCTCCACTGATTATCAATTCACTGATAAGCTCAC
+ACTGCCTGCCCAACTCAATTCATCGCAACTTCTTCTCCCTGCTTTTTTTT
+GCCATGAATTCGACGGTGGCTTCCCGTTTCTCATGGGGACTCATTCTGGC
+GTCGATCGATTTTTTGGCGTGCCTACTGTTCGCCTGCCTGCATGATGGAA
+CTTTCAAATTCGCGAATTTTACTTCGCAATTTGGCGATTTTTCGTTTTTT
+ACGAGGTTCGATTGATTGGTGGCCGAGTTAATTTTAGGCCACGAAAAATG
+AAAATTGAAGCCGAGTGTCATTTTCGCTGGAATTCTAATTTTCAGTGTGT
+AAAAATATAGAAAACTGCAAAAAATTTTGAATTCCCGCCAAAAACTAACG
+TTACGAGACCCAAGTACAGTGGAGCGCAGTTGCAAAAAAAAATTTTTAAT
+GATTTTTTGCAACTACGCTCCACAGTCCTTGGGTCTCACAACGTTGAAAC
+TAAAATTTTGGAATTTCTCCCATAACTTCTTATAATAACGATATTCGGTG
+GTCTCGACACGACATATTTTCATTAAATAAAACGGGTGTGCGCCTTTAAA
+GAGTACTGCAGTTTCAAACTTTAGTTGCTAAGCGTATTTTCAACAAAGCA
+ACGAAAATTTGAACTTACAGTACTCTTTAAAGGCGCACGCCCGTTTTTAT
+TAAAACAAAAACTTGTCGTGTCGAGACCGGGCACCGTAGTTTTGACGCTA
+AAAATAAGATTTATGAAAAAGCGGGTTTCCAGAAAATTTCACTTTTCAAA
+CTTTGATGAAAATTTGAAGTTTCCAGCCAAAATCGCTGCGAGACAGTGGA
+ACGAGTGCAGTAGAGCGAAATTGCTGTAAAATTTTGAAAAAAAAGTGAGA
+AATTTAAAAACACGGATTTCTGGCCTCCCCCGTAAATTGAAATGGAAGAG
+TTTGCCGAACTAGGCCACTTTGGCTCGCCCATATCTGGGGTAGATTTACG
+GCGCGTTGCGTGTCGCGACGCGATTTTAGTTGGAAAACTAAATGTTTTTG
+CCCGTGTGGAGTACACGACTTTCCCACGTGTTGTCCTCTAGGTGATTGTC
+AATGGAGCGCAAAAAATCCAATGAGGAAGGCCAGAACCCCGTGAAAAAGT
+ACGCGTTTTTGAAGCAATTCATCGAAAGAAGACAGTAAAAAAAAAGTCAA
+AAATTCAAATTTCCAATAGAAAAACCACCAAACCCAACAATTTTTCCAGC
+ACAATCGACCTATTCTTGCTGCAATTTTTCCGTTTTGCACTATGGATGGT
+GCCGGCGGCAATCCACGTGGCCAACAAGGCGGACACGTTGACAATGTGGA
+AAGAGGTCGGTGGCCGCGTGGCCTAGAAATCCCGAAAATTTCAAATTTTC
+AGCCAATTTTCTGCTCGGCACTGCTCATCTGCGCGGCGAGCCCCACAAAA
+TTGCTCCTCCTCACAGAAAAGCTGAAGCCCGATGAGTTCCTCACTTTCGG
+CGACACTGCCTTCCTTGTCTGGAATTTCATTTCCGCGATCATTTTGAACT
+CCTCGTGGACAAGATACTTCTCGCGAACTCCGTCTTCATATATAATTCTG
+GAGGATGAGGATGTAAGTGCGCTCCGCTGAGAAAATGTTTTGATCACCCC
+CACGATTTTCAGCTCGAGGTGGCTCCAAAACAAACGTTTGAGCTTATTTT
+CCGCCTGCTCCAATACTGCAAACGTGAATGGCTCTGGCATATTTCCGGAT
+TCTCGTGGCTCTTTATTTATTCGATCAGTAAGAGAATATCCATCGGGGGT
+TTTTTGTTTCGAATTTAAAAAAAAACACAAGTGGAAGAGTTTTTAAGATT
+TCTAGGCCACGCACCCACTCCAAAACCCCAATTTTCAGCCCGTATCTTCG
+TTCCCTATTACACGGGACAAGTCATCGCTACCGTGGTCGCCACAAAATCG
+TACCCAGCCCTCTCCAACGCTGTCTACATCATGACAATCATCTCGTTGGT
+GAGCGCTGTCGCCGCCGGATTCCGTGGAGGATCCTTCGAGTACGCCTACG
+CAAGGATCCAGAGGGCAATCCGCTACGATTTGTTCCACGGACTCGTGAAA
+CAGGATGTCGCTTTCTATGATGCTCACAAGACCGGAGAGGTGACTTCTCG
+TCTGGCTGCTGATTGTCAGACTATGTCGGATACAGTTGCGTTGAATGTTA
+ACGTTTTCCTCAGGTAGGTGTGGGTCCGTGACCGAAGTTCCCAGATCACA
+TGACCTAATTTTCCCAAATTCTTCCAGAAACTGCGTTATGCTCCTTGGAT
+CGATGATCTTCATGATGAAGCTTTCGTGGCGCCTCTCCCTCGTCACATTC
+ATCCTCGTCCCAATTATCTTCGTCGCCTCCAAAATCTTCGGAACATATTA
+TGATGTAAGTGCGCTCCAGCGAAAACGTTTTTCTAAAGTTTTGACCCCAA
+AATTCTGTCAAAGTGCCCCATTTTGGTTTGATCTTCGGAAAATGCGGGAG
+AAGAGGCGCAGGCTTTGCAACTGATATCACATGGTTAAGATTGTGCTGAC
+GGCACATGGAAAAATTCCCACATTTTTTTGTAGATCAAACCGCACCTGAC
+ACCACGTGAAATTTTTGACAAGTCAAGAAAAATTTCGGCAATTGTGAAAT
+AATCGAATTACCGCCGCACGTGGTGCCAGGCTGTCCCATTACGGCTTGAT
+CTACAAAAAGTGCGGGATGTTTTTGCCCAACAAATTTGACGTCAGCACGT
+TCTTAGTCATGCGAAATTAGTTGAGAACTCTGCGTCTCTTCTCCCTCATT
+TCTTGTTGTTCTACGTAGATCAAGTCGAAATGACCCACTCTGACATCACG
+TGCCGCCTCCCACCCCTGCTCCGACCAGGAATCAGCGGATCTACTTAGTC
+TCAACTTGTTTTATTTCAGCTCCTCTCCGAAAGAACACAGGACACAATTG
+CCGAGTCCAATGACGTTGCCGAGGAAGTTCTCTCCACAATGCGTACAGTC
+CGATCCTTTTCCTGCGAGAACGTCGAAGCCGATCGCTTCTACGGGAAGCT
+CACCCACACACTTGATGTCACCAGAACCAAGGCGATCGCCTATATCGGAT
+TCCTCTGGGTCTCCGAACTTTTCCAGTCGTTCATCATTGTGTCAGTCCTC
+TGGTATGGAGGCCATCTAGTGCTCACCCAGAAAATGAAGGGAGATCTTCT
+AGTGTCATTTTTGTTGTATCAAATGCAACTCGGAGATAATCTTCGTCAAA
+TGGGAGAAGTCTGGACAGGATTGATGCAATCTGTTGGAGCAAGTCGTAAA
+GTGTTCGAGTACATTGATCGAGAGCCCCAGATTCAGCACAACGGGGAGTA
+TATGCCGGAGAATGTTGTTGGAAAGATCGAGTTCAGAAATGTTCACTTCA
+GTTATCCAACTCGTTCCGATCAGCCAATCCTTAAGGATCTCTCGTTTACC
+GTTGAACCAGGAGAGACTGTCGCATTGGTTGGACCATCTGGCTCTGGAAA
+GTCTTCGTGCATTTCTTTGCTTGAGAACTTCTACGTCCCGAATGCTGGAC
+AGGTTTTGGTGGATGGAGTTCCGTTGGAAGAATTCGAGCATCATTATATT
+CATAAGAAGGTACGTTGGCGTCAATTTCGGTTCGACAAATCGTTTGCCGG
+TTTGCCGGCAATTTTAATTTTTGGCAAATTGCCGATTTGCCGGAAGTGTT
+TAGAGTGCTTTTTTATAAGACGGAAACACTTGAAACTGTGTCCGTTTTTA
+AATTTTTGTGCCGGTTGGCGATTTGCATGATATTTTCAATTCCGGCAATT
+TGCCGATTTGCCGGAAATTTTCCATTATGGCAAGTTGCCGATATGCCGGA
+AATTTTGATTTCGAAAAATTGCCGATATGCCGGAAGTTTCAATTCCGGCA
+ACTCGCCGATTTGCCGGAAATTTCAATTCCGGTAATTTGCCGATTGGCAG
+GAACAAATCGTTTGCTCGCAGTCTATTCGGATAAAAATTGCGCCAACTGT
+TCATCCGTTTGCACAGAAAAAGCATTTCCGCGCTTCGCTATTGGCCAATT
+TCAAAATAGTGGGCGTGACCAACCAATCACGGGTGTTTCTTGCTTTCCAT
+TGCTGAAACTGTGATTGGTTGGTCACGCCCAATTTTTTGAAATTGACCAA
+TTGCGAAGCGATGACTTTGGACGCAAGAAACTTCCGTTTTCTCCTTTAGC
+TGTCGATCGAGATTCTCTCCTTTAAAAACACATTGCCGATCTTTTCAAAG
+CCCCTGTTTCAAACGACACAGCTAGTAACAACAAAAAACCTCGAAAACTT
+CCAATTTTTCAGATCGCCCTTGTCGGCCAGGAGCCCGTCCTGTTCGCTCG
+TTCTGTGATGGAAAATGTCAGATACGGTGTCGAAGTGGCGGATACGGTAA
+GCACGATTAAATGCACCATGAGCCAAACAAAAAAACTTGTTCAGGAAATC
+ATTCGCTCTTGTGAAATGGCGAATGCTCACGGATTCATTATGCAAACCAC
+GTTGAAATACGAAACAAACGTCGGAGAGAAGGGAACACAAATGTCCGGTG
+GTCAGAAGCAACGTATCGCAATTGCTCGTGCTCTTGTTCGTGAGCCAGCG
+ATTCTCTTGTTGGATGAAGCCACGTCGGCGTTGGACACCGAGTCCGAACA
+TCTTGTTCAGGAAGCGATTTATAAGAATTTGGATGGAAAGAGTGTCATTT
+TGATTGCACATCGATTATCGACTGTTGAGAAGGCTGATAAGATTGTGGTT
+ATTAATAAGGTGAGTTGCAATTGCGCTCGACCGAGATTTGGTCGCAAACC
+TGACACGGGGTTCTGGCCTTCCTCATTGAAATTTCCGCGCTCTATTGACA
+ATCGCCTGCCGGACAACGCGTGGGAAAGTCGTGTACTCCACACGGACAAA
+TACATTTAGTTTTACAACTAAAATCGAACCGCGACGCGACACGCAACGCG
+CCGTAAATCTACCCCAGATATGACAGAGCCAAAATGGCCTAGTTCAGCAA
+AAACTCTTCCATTTCAATTTATGAGGGAATCCAGAAATCCGTGCGCCCGT
+GGTGTATTACTCGTGGATAACTGCTCATATTTCAGAATTGAGAATTTCGC
+TAAAAACTGTAGAATCGCGTTAAAAATGAGACCTCACCAAAACAGGATTC
+ACGAAACAAGAATTCACAGAAATAGTATTCAGTGGGCGCAGTGTGCGCAG
+TGTGCGCGGGGGTTGCGAAAGCACACTTTTCGGTCCCGCCCCCTAAATCG
+TGTTTTTCGTGAATACTGAATCTGGGAAATTTGAAAACTCGGCGAGTTTT
+TCTGTGCGGCACACCCACGTGGTGTCAGGCTGTCTCATGGCCCGACAAAG
+GGTACATCAGTGTAAATGCGCTCTACCGAACAGAACGCATAACCCACGTG
+GTGCCAGGCTGTCCCATTACGGCTTGATCTACAAAAAGTGCGGGATGTTT
+TTGCCCAACAAATTTGACGTCAGCACGTTCTTAGTCATGCGAAATCAGTT
+GAGAACTCTATGTCTCTTCTCCCGCATTTTTTGTTGATCTACGTAGATCA
+AGCCAAAATGAGACACTCTGACATCACGTGATAACCTGGTTGATACTACG
+CGTACGGCTTGCCGGGCCGTGTTTCTCATTGCGGTTTGATCTACAAAAAT
+GCGGGAATTTTTCCCCCAGGAAAGTGTGACGTCAGCACACTCAGTCTGCG
+TCTCTTCTCCCGCATTTTTCGAAGATCAAACCAAAATGAGACATTTTGAC
+ACCAACACACACACACACACACACACACACACACACACACACACACACAC
+ACACACACACACACACACACACACACACACACACACACACACATCATATT
+TGACGAGCAAAATCGGCCCCATAATTACAGGGAAGAGTCGAACAAATCGG
+AAATCACGAAACCCTACTGAAGGACACCAACGGAACCTACGCGAAGCTCG
+TTCAACGCCAAATGATGGGAGATCAGAAGCCACGTAAACGGCCGGCGGTC
+GCCAGATCGGGACCTCAGCCAGCCGCGTCAATCAACGTGGCAGGACCATC
+GCAGGGTAATGCAATGTCCCTGTTGTCGACGTCTTTCAGCCAATCTGCCA
+GTAGTGTTACTTCTCATTAATTGTTTTTTCTTCTTGTTAATTGGCAAAAT
+ATTATGATGAACTTGTTGGGTTGATTAATTTGTAAGAATAAAGTATACAA
+TTATTCATTCATTATTAAAATTTGGGCACATAGAAAAAATTGTGGAAAAA
+CTGTAAAAAATCTGCAAAAACGTGGAAATTATTCAAATCAACTCCAGGTA
+GTCGTTGTCGACATCGTCTCGCTGCCGCATCGTGTTCTGAAAATCCATTT
+TTCACTTTTTTTAAAGCAGATTCCCAGCTAACCGTCGACCGGATCGTGTT
+GTTCCATCCGCGGATTTGAGAGTAGGAGCTTACGGTGCCACGTGTCTCGT
+TGGCAGCTTGCCAATTATTCACAGACAGCCTGTACGAGTCGCTCAACAGT
+GGACCGGCGTTTAGAGTCTGAAAATATATAACGGGAACACTAAAATTTTA
+GAATGCGTATTGTGCAACACATTTGACGCGCAAAATATCCAGTAGCGAAA
+ACTACAGTAATCCTTTAAGTGACTGCTGCACGTGGTGCCCAGCAGGGCTG
+GGAATTTTTTGGTTTTTTGGTTTTTTTGGTTTTTTGGGACCAAAAATCCA
+AAAAATCAAAAAAAAAAACAAGTTACCGTGTCTAGTCTCGACTCGAGACT
+ATTCTGTATTAAAATACATCGAAACATGTATTTTAACACAGTTGTGACGT
+CATAATGTAATACATTTGGCAACATTACTTGAATAACCCCATTAAAAATC
+ACCTAAAGCATAAAACATTTTTTGGTTTTTTTTTGGTTTTTTTGGTTTTT
+CCAAAATTTCAATTTTTTTGTTTTTTGGTTTTTTTGGTTTTTCAAAAACT
+TCAAATTTTTGTTTTTTGGTTTTTTGGTCCAAAATTTTTTTTTGGTCCCA
+GCCCTGGTGCCCAGCTGTCCCATTACGGTTTGATCTACAAAAAATGCGGA
+AATTTTTTGCCCGAAAACATGTGACGTCAGCACGTTTTTAACCATGCAAA
+ATCCATGCTTCTCCCGTATTGTTTGTAGATCAACGTAGATCAAGCCGAAA
+TGAGACACACTGTGACCGCGTGCTACTGTAGTGCTCGTGTCGATTTACGG
+GATCAATTTTCGAAATGATTATACATATAATTATCGATAGAATAATAAAA
+TTAAGCAAAAAAAAATCGGAAAATAATACGAAAAAACAAAGGAAAATTGA
+AAATCGCTGTCAAAATTCGAAAAAAATTAATTTCGAAAATTGAGTTCCCG
+TAAATCGACACAAGCGCTACAGTAGTCATTTAAAAAGGATTACTGTAGTT
+TTCGCTACGAGATATTTTGCGCGTCAAATATGTTGCGCAATACGCATTCT
+CAAAATTTTGAACTCTCCGCCTCTCACAGCTGGGTCTCGTTAGGTATGGG
+GGCGGATCCTTTTCAATTGGCGGTGGAGCGCGATTGAAAAAATTTTCGAT
+TTTTTTTCGATTTTTCAGAAAAAATATCGATTTTTTCCGATTTTTCAGAA
+AAAAAATTCGATTTTTTTTTGATTTTTCACAAAAATTATCGATTTTTTAG
+ATTTTTCAGAAAAAATATCGATTTTTTTTTCAGATTTTCAGAAATTATTT
+TGATTTTTTTTTAATGTTTTGTCCCTTTTTCTGAAATTCTACCTCATAAT
+GATTGCTTCTTCCACTTCCGCCTCGCTGCCCGTAGTTCAGTGTCGAGTAA
+TTCGCATTCGATACTGTGTAAATCGACAGTGGAATAACCGGGTAGATCAT
+AATGTAGTACAATGTGGCAAAGTGGATCACTAACTGAAAATTATTGGATT
+TTTCTAATAATAAGGTGGGGAAATCCGAAATATGTGAAAAATATTTTTAA
+TAAACAAATTTTCCCCTGATTCCGAATATCTATATGAAAAAATTCAAAAA
+AAAATTTTCCAGATTTTATATTTAAGCTTGAAATCGCTTGAGCCCGCATC
+ACTATTTTCAAATGCTTGCCCAAAGAAATTTGCATTAGAGCGCGCTTGCA
+TAGTTTGATTTTCTTCATTCAAATATTGTATTTATTACCGCCAAATTCAA
+TTTTTTAACCGGTTTCATTCATTTTTGTCGAAAAAATATATTTTTCAGAA
+AAAAACCGGTGAAAAAAAACCAAAATCGACAAAAACTAATGAAGCTGGCT
+GATAAAAATTGAATTCGGCGAAAATAAATAAAATATTTAAATGAAGAAAA
+TTCTTAGGCGCAAACGAAATTCGCCATTTCAAGCTTAAATATAAAATCAG
+GGATTTTTTATTTATTTTTTTTTCACATTGATTTTCGAAATCAGGGAAAA
+ATTTGGGGTTAATTATAAATATTTCCCAGATTTCGGTAAGAAAAATATGA
+TTATTTTTTTACTAAAAAATAACCCCCACCAGTAAAGCGTAGAAAATTGA
+GATGATAAATGCGAAAATGATGAACGCGGAAGAAAAAAAGTCGGGATTCT
+TTTGGGCAGTGCTGGAGTAGTTGAAGATCGAGATGATTGTAGAATAGTAG
+GACAGGAATGAAACAATCATCTGTAATTTATTTTTTTAAAGCTTCCAGGT
+CAATACACGTGGTGTCAGAGTGTCTCATTTCGGTTTGATCTACTGTGTAG
+ATCTACAAAAAATGCGGGAGAAGAGACGCAGAGTTCTCAACTGATTTCGC
+ATGGTTAAGAACGTGCTGACGTCACATTTTACTGGGAGAAAAATTTCCGC
+ATTTTTTGTAGATCAAGCTGTGATGGGACAGCCTGGCACCATGTGGGTGC
+CGAGGGTATTGCTTTTTGGTATTTTTTGGAATTTCGAAAAAAACTTTCCG
+ATTTTTTTGAAAATAGCTCTTTTTATAGAAGAAAATAGTTTTTTCTCATC
+AACACAAATTTTAGAACAATTTTTTCGATTATCCGGAAAATTGAAAACTT
+TCGTTTTTCTATGTTCCATTTTCGATTTTATAAATTTGGGAAAACCTAAA
+ATTTCGATTTTTTTTGAAAAAAAAACGAGTATTCAATAATTTATATATTA
+TAGGCATTCTTTTTCTCTAATTTCTTCTGAAAAACATTAAAAAAAAATTT
+TTTTTTTTTTAAACCAATTTTCAGTAATTTTTTTCTGTAAAAAATACGAT
+TTTTTTCCAATAAATTTCTAGTTTTTTCTCTCTTTTCGTACATTTGGACT
+GTTTCTAATTTTTGCTTGCTTTTTTCTATATTTTTTCTGCGATTTCCTAT
+GAAAAGTACCAAAAAATCGGAAATTGTTTTTTTTTTTCGATTTTTTAGGA
+AAAAAAACGATATTTCCTATAAATGTTTTTTTCATAAGTAAATACTTTTC
+TCCTTTTCCTTTTGATCTACAATATTTCGAATTTATTTTGAAAAAAATTT
+TTTAAACGTTTTTTTCTGAAACAAAGACCCAAATTTTCAATAATTCAATA
+ATTTTTCTGGATTGTTCAACCGAAATATACACATTTTTCAATAAATTTAT
+AGTGTTCTCCTCTATTTTTGTTGATTTTTACTACTATAATTTTTTCAAAA
+TTTTCGAAAAAAAAAATTTTTTTTTTGGAAAATTTTAATTTCAATTCGAT
+TTAAAAAATATAAATGTTCATATTTTTTCATCGAAATATATATTTTTTGA
+TTTTTCAACCTTTAAATTGTTTCATTTTCTCTGAAAAAATCGGAAAAATC
+AACAGAAAAATCGAATTTTTTAAAAATATTTTCCGATTCCGACCGTAATT
+TTTATGAAAAAAAATCGGTTTTCTCGTTATTTTCTACAACAAAACCTCAA
+AAAACATGCTGGGCAACGTCAAAATCGCTCGATATCGAATCTTCAGCTCA
+GTCTCATGTTTCACCAAATACACCGCATACAGAAACATCGTGCAGCTGAT
+GAAGAAGAAAATGAGCAGATATGCACACTTTTCCACGAAAAATTCGCCCG
+AAATCATGAAACGTGGCAAATTGAGCACAATTCGATGGAGCCAATAGCAG
+GTCGATGAGCTGCAGCGGAAGCTTTCATTGGGATCTGTGCAGTACGTTGG
+AACCGATAAATGTTCCTGCATTGATCGGATACAGTAGACGAGCAGGCAAA
+TGTATTTTACAAGTGAGATATTCTGAAAATTTTTGAATTTTTTTTCCGAA
+TTTAAAATTTTAGTTTCTCGATTGTTTTGAAGTAAAAAAATTGATTTTTT
+AGAAAATTATATGTTTTGTTTAATTTATTTAAAAATCTTTAAAGGTGGAG
+TAGCGCTAGTGGGGAAATTGCTTTAAAACATGCCTATGATACCACAATGA
+CCGAATATCATGATAAAAAAATTCAAAAAAATTTTCTAAATTTTATAGGT
+TTTTTTTTGAAAATTGAAAAATCTCAGTTTTTGCCTAATTCCAATTTGAA
+TTACCGCTAATTGGATTTGTTCGGTGGAGCGCGCTTGCACGTTTTTAAAT
+TTTTTTATTTTATTTTATGTTATTTTCCACCGATTTTTAATGTTTTCGGT
+GTATTTTTGCTCGAATTTTAGAGAAAAAGTCAAGATAAATGCAAATTTTC
+AATTAAAAAGCACGCTTACAGGCGTAAAAATGACAAAGTACCGATTTTAA
+ACGATTTCCAACCTGAATTAATTAATTTCACTGATTTACGCCTGTAATCG
+TCTTTTTTAATTGAAAATTTGCATTTATCTTGGCTTTTTCTCTAAAATTC
+GAGCAAAAATACACCGAAAACATTAAAAATCGGTGGAAAATAACAAAAAA
+TAAAATAAATAAATTTAAAAACGTGCAAGCGCGCTCCATCGAACAAATCC
+AATTGGCGGTAATTCAAATAGTAATTAACAAAAACTGAGATTTTTTTCAA
+TTTTCAAAAAAATCGTATAAAATTTAGAAAATTTTTAAAAAATTTTTTTA
+TCATGATATTCGGTCATTGTGGTACCGTGTTTTAAAGCAATTTCCCCACT
+AGCGCTACTCCACCTTTAAAGTGCTAATGTAAACTTTTTGTACACGTGGT
+GTCAGAAAGTCCCATTTCGGTTTGATCTACAAAAAATGCGGGAGAAGAGA
+CGCAGATTTCTCAACTGATTTCGCATGGTTAAGAACGTGCTGACGTCACA
+TTTTTTTGGGAGAAAAATTCCCGCATTTTTTGTAGATCAAACCGTAATGG
+GACAGCCTGGCACCACGTGTTTGTACAATTACACATTATCCTGGAACTTT
+CCAGAAAATTTGAATTTCCCGCCAAAACTTATGGGTCTCATCACGATGAG
+TCACTAACCTCAAACCGATATATTTTCTAAAAACAAAAACTCAAATTTTC
+TCAAACTACAGTAATCCTACAGTAATCCTACAGTACCCCTACAGTACTAC
+TACAGTACCTTGGCATTGTCCCCCACCAATATACAACCCAATATACCTTC
+AAAAAACAAACACGTAATTTTTCCCAAACTACAGTAATCCTACAGTACTC
+CCACAGTACCCCTGCAGTACTACTACAGTACCTTTTTAGAACATTTTTCT
+GTTTTTCGATTTTTTCGCAAAAAAAATTCAGTTTTTTCAGCAAAAAAATT
+GATTTAAAAATATTTCAAGTTACTTTTTAAAAGCTTTTCAAAAGTTTTTC
+AATCCGTAAAAATAAAATTTTACGAATTCTTGTATTTTTTAAATTATCTG
+AAATTTTTTTTTCTCAAAAAAAAAACTTTTTTTTTCAAGTTTTCAATTAA
+TTTCGGCAAATTTCAAAAATTTTAGGTTTAAAAAAATTCAATTTTTATGC
+TTAACATTTTATCGACATAAAAATCATTAACAACTACGAACAATTTGTGG
+AAAACGTTTTTGGCAGTGGAGCGCACTTGCGCCTCGTATTCAAAAAGCCA
+CACAAAATGGTGAAATATTCCCAAAAATCAAATAATTGTTTCGCTACGAG
+ACCCAAAATACCGCAAAATAGTAATTTTTACCATAGTAATTTTCAAAAGT
+GGCACGTAGACCTGATGAAACGTGTCGTTCACCTCCTCCGAGCTTCTGCC
+ACGTGAGCTGGTGCTCCGGCATGGCTGATACATTTGTGAAGTTCGCTAAA
+ACAGAAAAATATTATAAATAAGCGGAAAATTTCGTGGTCTCGACACGACA
+AAAAATAATAAAAATTATTCGTGGTGAGACCCGAGTTGTTTTGGAGCAAA
+ATTCTCAAAATTGGGGTATCACGTGGTGTCAGAGAGTCCCATTTCGGTTT
+GATCTACAAAAAATGCGGGAGAAGAGATGCAGAGTTTGCTGACGTCACAT
+TAAAAAAAAATTCCCGCATTTTTTGTAGATCAAACCATAATAGGACAGCC
+TGGCACCACGTGCGGGGATTAAAACCCGCGCCGCACAGAAAAAAGGCGGA
+GTGTTATTTCGCAACACCGCGGCACGGTTTTTTGTTGATCTTTTTCAATA
+GTCTTGATATTACTTGCGATTTTTGCAAATTCAAAAAATCAACAATAAAC
+CGACCGTGCCGCAGGGTTGCAAACTCCGCCTCTTTTTCTGTGCGATGCTG
+ATTTTTTGCGAAATTCACGAATCAAAAAGCACACGTGGTGTCAGTGTCTC
+TCATTTCGGCTTGATCTACGTAGATCTACAAAAAATGCGGGAGAAGAGAC
+GCAGAGGTCTCAACTGATTTCGCATGGCGCCACACATTTTTGGACAAAAA
+ATTCCCGCATTTTTTGTAGATCAAACCATAATGGGACAGCCTGGCGGGGA
+TTAGAAACCGCGCCGCACAGAAAAAAGGCGGACCGTAGTTTCGCAACACC
+GCGGAACGGTTTTTGATATTACTTGCGATTTTTGCAAATTCAAAAAATCA
+ACAAAAAACCGTGCCGCAGGGTTGCGAATTTACGCTCCGCCTCTTTTTCT
+GTGCGATGCTGCTTTTTTTGCGAAATTCACGAAAAAAAAAAAGAAAATAA
+AAGTACATTTACCGATAAAAGTGACGATAGACCGCCGATATACATGGAGA
+GAATAGAGAGAGAAATGTGAAGTTTATTAGAAAACAATTTTGTAAAATTA
+TGATGATGATGAAGATTTGCGGAATCTGGTAATCGGTTTTAATTGCCTTT
+TCTATTATATTATATTAATCACTTGATGATGTACGGCTTTGCGCTTCCTC
+GTCCACGGTCTCCAGATGACGGAATCCACGTGGCGATACTGATCGATTGT
+GTTTTGGAGTGGTGGTGCTGCTGGTGCTGGTGGAGGGAATTGAGGTGGTT
+GCAGTGGATATTACGCTGAAAAATTGAAAGGATTGGTGGAGGAAATGAGA
+GAAATTTGAGAGCATAAATTTTTAAAAATCGAAAAAAAATTTTTTTTTGC
+TATTTTTGGGCAGAAAATGGCGAAAACGGTGTTTTTTTGGGTAAAAAATA
+ATAAAAATTTACAATTTTTTTTGACAGAAAAATGCGGAAAAGCTGTTTTT
+AGGGTTGAAAAATCAAAAAAAAAATTTTTTTTTGCTATTTTTGGGCAGAA
+AATGGCGAAAAACGGTTTTTTCAAGTTTAAAACATCAAAACAATTTTTTT
+GCAATTTTTTTACAGAAAAATGAGGATAAGCGGTTTTAAAGGTTTAAAAA
+ATTTTTTAAAATTTTTTTTGCGAATGGAAATTTTCTGAAAAATCGTGCAA
+ATGCCTAATTTGTGCAAAAATCTTATCTGGTCAATGATTTTTAAGAGAAA
+ACACCGGTTTTAGAAGGGAAAAAGGCAAAAAACTGGATTTCCAGTGAATT
+TTATACTAAAAATGGAAAAAATTCAGAAATTTTTTAAGGAAAAATCAGAA
+TTTTCGCAATTTCTACACGAAATATATAGAAATTGAGGAGAACCTCGGAT
+TTTTTGCGGAGTTTAAACAATAATTTTTCGGCTAAAATTAACGATTTTCA
+GAGAAAAAACTTAAAAAAAACAGAATTTCAGTGAATTTTACACGAAAAAC
+GTAGCAAAAAGAGGTTTTTAGGGAATTTCCAAGTCAAATTTCCGAAATTC
+TTGCGATTTCAACCCTGAAAAATAGCGAAATTGAGGAAAATCTCGGATTT
+TTGCAGATAAATAATATTTTTTCCAATGATTTCCGTCTCCAAAACACAGA
+ATAATTTACCAATTCGACGATGGTGAGGAGGGAGAGCCCAGCTCGTTGGT
+GACAGCCGTGAGATCCGAGAACAAATTGACGCTGGCTGAAAAAATGGAAT
+AAACGCTAAATTGATGATTTCCGCTATTAAAGTGCATATAGAAATACGAA
+AAAGCAAAAAAAAAAATTTTTTTTAACCTTTTCCCTGGAATCGAAGAGCA
+GTTTGCTTGCGGATTGGACGTCGAAAAGGGCCTAAAATTCTCATTTTTCG
+GCCTGAAATTCCTCGAAAAACCCACTATTATTGGTAGTCGGAGATGGCTG
+ATCGCCTCGTCGCTGGTAATATAGCACGCCTAGCCAGAATCCGTAGAGAA
+AATAAATATAGACTGCCCACACTAGGATGATGGGAAGAAACGACAATCGG
+CAGGCGTCTGGAGTGAAGAAATCAAGATTTTTCAGATTAAAAATTAAAAA
+TCTTTAAAGGTGGACTACACCCTTGTTGGGAAATGGCTTTCAAACATGCC
+TATGGTACCACAATGACCAAATATCATGATTAAAAAATTCAAAAAATTTT
+TCTAGATTTTATATGATTTTTTGAAAATCGAAAAAATCTCAGTTTTTGCC
+TAATTCCTATTTGAATTACCGCCAATTGGATTTGTTCGATGGAGCGCGCT
+TGCACGTTTTTAAATTTATTTATTTTATTTATTGTTATTTTCCACCGATT
+TTCAATGTTTTCGGTGTATTTTTGCTTGAATTTTAGAGAAAAAGTTAAAA
+TAAATGCAAATTTCCGATTAAAAAATCACTGAAAATGCGTAAAACTGAAA
+AATATGCTAGTTTCAGGTTTGTTGTCGTCGGAACTCATTATTTTACAGTT
+TTACGTATTTTTCACATTTTTAAACACTTTTTAGCAAACATTCTGCATTA
+ATCTTGCTTTTTTACTTCTCTTTCCGATAAAAATACACAACTAATGAAGA
+AAATCAGTGACATAATAATAATAATAATAATAATAATAATAATAATAATT
+TATTACGCTCGCTGGGAGACGTGAAGGAATACAGAATACAAAAGTTATCA
+TTGTTCGCTTGAACTAGAATTGGTGCAGTCGGGCAATCGTTTCCATTCCA
+TTAAAATGTTGTCCTTGTCCTTGCGTTGTCCTTGCGTAGACTCCCCCATA
+GTGGGCGAGCGATTCCCGAGTGAAAATAATCACGGAATGAAAAAATAGAA
+GAAAAATAGAATAAATTAATAAAAAAAATAATGCAAGCGCGCTCCAACGA
+ACGAGTTCAATTGGCGGTAATTCAAATAGGAATTAGGCAAAAACTTTTTC
+AGATTTTTTCAATTTTCAAAAAATCATATAAAATTTATAAATTTTTTTTG
+AAGTTTTTTAACGTGATATTTGGTCATTGTGGTACCATAGGCGTGTTTTA
+AAGCAATTTCCCCACAGGGTGTAGTCCACATTTAAAAATTAAAAATTAAA
+AATTCTACCTAACAAAATCGAAAATTTCAGATTCTCCTTGATTAAAAGCT
+TTATTATTGAGTAAAGAGTCCGCAGCGTCCACACGGAGAGCGGGTACAAG
+ATGGAAATCTGAAAATATTTAGGATTTTCAAGGGAAAATATCGATTTTTT
+TTAGCAAAATACCACAGAAATTGCGGATGGAATGAGTAGAAGAGCCGGGT
+TGACTTTCCGGGGAAAGTTTCGACGTGTGATGCTCGTCTCGGAGAGCCTC
+ATTCCCAAGAATCCGGTTGCGATGCTGAAGAAAATCGATGGAAAAAGTCT
+AAAATATCCCCTGAAACCCTACCTAAAAATCAGAAAATACGAGAAAATAT
+TGATTAAATTCCGAGCCGGCACATAATTCGGGCGGATCAGCACTCCATTG
+AAGTTTCGAAACGTTTCGCCGTTCCACTGAAGTCCATCGAAGCCGGGAAC
+GGATGGCGGCTCGAAATGCTCGTCGACACTCATTTGACTGGCCCTGTAGA
+GCCCGATGATGGCAATGGCGAGCATTCCCACTTCCACATGGAATATCAGG
+CTCTGAAAATTAAAATTTAGCTTTTAGACGGAAAAAATCGATTACTTTGA
+CATGAACTTGATCGAAAAGCCAGCGATACGGGTATTTTCGGTGCAGGCGG
+CCTGATTCCGGACGTGCTCCTCGAGATATATTGGAATTTGTCGAGCGGAT
+ACTAATATCTGCCATTTTTTCGCTGAAAAATCAGAAAAAATAAGTTTTAA
+AACAGAATTTTAATGGAAAAATAAACGGAAAAATTCGAAACTTTTTTTTC
+CGCCATTGAACACCAATGTGCCTTTAAGGTACGGTAGCTCTTCGTGGTGA
+GACCACTGCGCCGCGCATCTGATTTCTCGTGGGAAATTTGTTTCGAATCC
+TACGTTTTTTACAGATTTTTCTTTTTTTTCGTTTCGCTCATCATTTTTTT
+GTTGCAAAAAATCCAATTTTCAGACAAAAATGTCAGAACGCCAATCCAAA
+TATTTTGACTATCAAGGTATCGTCATTTCCTCCACTGGACAAGATAACCA
+AGATTCGGAGACGGACCTCGTTTATCTCATTCAAGCTCATGTACGTGAAT
+TCCCTCCGTTTTCATATTTAAAATAATAAGCTCGTTTTCAGGGAAAAGCG
+GCCCCGAAGAACATCATGTACGGTGTCTCCAAGTGCGCATTTGTTCCAAC
+AAACTTGGAGAGGAATTTCGATAATATCGAAGAGGCAAAAAATCTTGAGT
+CAGTATTTATTTGATTTGAGCCCATTTTTAATCTGTTAACACTTGAATTT
+TTAGACGTCGATCCAAAATCCCGCTAAAGTTCGGTGAAGTCATCCTATGG
+AACGAATCGGACTGTGATCACGATAAGAGGATAATCCTTCATATCAAACG
+AGAAAAACCAATTTATGAAGCGTCTTCCAGCAGAAATGGACTTATTTTGA
+AAGTCGGTGGCGTCATCCAGCCCACCTCAACGACCTCGTTCTGGACGCCA
+TTATGCACCGTCACCATGCGTATGTTTCTTCTTGATTTTCGTCTCTCTAA
+CCATATATTTATTTCAGCAGAGACAGAGGCGACCCGTGCGGAGCCAGACG
+TTTGGCTATACGCCTGGATTCGATTCGAAACTACCATGAAGAGTGGTCTA
+GATCCTTTCAATATGACTGCAACATTCGAATCGTTTGACAGTTGCGATCC
+ATCCGACCAAGCACGCGTCTGTGAAGCGGTATTTGCTTTTTAAAAATTTT
+TTACGGGATTTTGAACAAATAACTTTCAGCCATGGAACGCAGGCTCTCCT
+GACTCTAAATTCGGTGTTTGGCGCCCGGATCCAAAGCCTGCTGATAGCGA
+CGACGAAATTGATATCGAGCCGAGAGAAGGCTGGCACTTGCCAGAAGACA
+AATGGGCCGAGGTTAAGGTTGCTTTGTGGATTCTCGTTGACAATTTGATT
+TTGCAGGTCATCAAGATGCAGCTTGGCCTGTATGTCGGCGAACGCCTACT
+GATTTGCAAAGAACTCTCGCAGTTCGACTTTATTATCCCACTGCAGAAGC
+CATTTTCCCGAGGAACGGACAAGACTTTGATCTACCCAGCCGTCGGAGAA
+TACTTTCATTTCAGTGCTATTTGGTCGATGCAGCACAACGGTTTTCTGAT
+CTATGAGCTTCAGCCAGTTCCACTTCTCAGACAGCATGTAACCTCTGTCA
+ACGGAAATGTAAGTTATAATATTGATTTTTTTGTCCAGAACATAATTTTT
+ATTTCAGCTCCTTACCCGCGTCGTTCCTGCCAGTATCAGAGGTCTCTTCG
+TTGACAAGGAGGGCACTCTTGGATTGATTGATGACCCACACCATCTTCTT
+TCATTCTTCGAGTTTCATCCAGCTGGTTATGAATTCTTGAAGGCTATGGT
+AATCATGAGTGGGTCTTATTTTGAAACAAACGCTTTCAATTTTCAGGCCG
+AAGTTCGTGCTGTTCGAACTTCAGAAAACAAATCTGTCCGTTACCGCATT
+GTTCGTACATCGGGAATGTCCATTTTTGAAAACTGGCTTCGTGATACTCA
+GGTCTCTAAAGTTAAATTAAACTCGTCCTTTTCACCCCTGAATTTTTCAG
+TTCGTTGTTGGTCCAGTCAAAGGAATTCGAATCAATGAAGACACTGTCAT
+TTGTGCCAAACATCCGAATGTCTACTTCAAAATCCCCAATAACTTGAAGG
+AAGGAATCCCCATTGGCGGAGGAGTTCAATTCGTTGGAAAGCGACAAGCT
+GGAGTCGACAGTGAAATTATGATCACCGAATGTTCTCCATGTCCAGCGTT
+CACTTGTAAAAATTACTCGGTCTCTGGTGATACGGTTAGTCTTCAATTAT
+TTAATAGTTTTTATTCTATGAGGAAAATATTCAGCGCTTGTTCCAAGTGT
+ACTTGAAGCCAAATTGCGATCATGAGCAGTTGGCGGAGAGTGATTCGATG
+GGATTTGTGGATTTCAGAGAGTTGGAGACTCCATGTAGAGGAAAGTGAGT
+GTGTCAGGATTTGTAAAAATAATTGTAACTGAATTTTAAGGTTCCTGGCA
+TGGGTCCGTGAATCCATTACTGTCAATGATTGTCGCCGTGCTGCTACCAT
+CATGGAAGTATGCTCGACAGCCATCTGTCCTCCGTTGATTGCAATGAGCG
+CGAATTCGAGCAGAGCAACATCGGCCAGAACTACGCCAGCTGGAAGTTCC
+ATTGGATCCAGATCATCAATTCAATCAAGAGCATCTGCAGCTACTTCAGT
+GAGCTCAAACGTAAGTTTATTTTTAAGGTTGGAAGATGATAAAAACAAGT
+TTTTCAGCGATTCGTTGGCCCTTCAAGCCGCAGAACTCCATCTGGTACTC
+CACAAAGCTCAACATCTTCCAGGGTCTAATTAAATATATACGCATCCCGT
+TTTCCCCCGTATTTGTGTTTCAAATGTTCTGCTCATTTTTAATCTACCCG
+TTATCCAACCAAACATTTATTTATTTAAACTTCAAGTTCCACCACCATCC
+CATTCCGCACAACTTGTCTCTCGTAATTTTCTCGTGCTCTAATGAAGTTG
+TGGTAGGTTATTCTAGTGAATACACCCATGTTAAGCAGCGAATACATCCA
+GAAAAGTCCCAACAAGCCGGCAGCGAGATACTCCCCCCAAAATGATGGTT
+GATCGGTACATCCAAGATAGGGTAGCATCGCGATAGACGTGAGCAAGTTC
+GTTATGCACTTGAAAAACTGAAATTTCAGAAAAGATTAGGTGTATCAGAA
+GGTTAAAAACAAACAAATGACATATAGATGAACGAAGCCAGTGATGGAAT
+CGGATTCCGAATACGAGAAGCCATTCCCGGAGATACTGTGATAAGAATCT
+GTGTGATCGAGAACACAATGAGCACACCCACCGGGAACATGAATTCCATG
+GAAACACGGAGGCAAAGGTCACAGTACTGCAAAAAATGCGAAATTTTGGC
+GATTTTTGCTCTAAAAAATGCACTGGCCGGGTCTCACCACGACAAATTTT
+TGTTGTCAGTTGAATGCCAATAGAGTGTGCGCCTTTAAGGAGTACTGTAG
+TTTCAAACTTTTGTTGCAATCGATTTTACAGTTTTCCCGAGAAACAAAAG
+TTTGAAACTACAGTACTCCTTAAAGGCGCACACACTCTTTCCGCATTCAA
+CTTAACAAAAGGTTGTCGTGTCGAGACCCGGCCACTGCATTTTTGTAGCA
+AAAAAAATTTGAAATTTTCAAGTCTGGATAATAATATATAATATTTTTAC
+CTCAACTATGGGAATTTGCATTTCCAAACTATCCAAACAATCGCTGAACC
+CGAAAGCATCACAAATAATCGATCGATATTGTCGCGGAATGTCACGTATC
+GATTGGTAGATCATGAATATGTTGCCAAGTAACGCGAAAATCTTGAAAAA
+TGGAGGATTTTGCTTTTAAAAAATCCAAAAAAAAAAACTTAAATTCGACA
+ATTTCCTGTTTGAATTCCCTCCAAAATGAGAACTGCAGGACCCATCAGCG
+ATTTGAGTGGGCGGAGTCCGAGGGCGCTGATTGGTCGTGCAGTTCTAATT
+TTGGAGGGAATTCAGCCAAATTTGAAAAATCTCGTTTTTTTTGCAATTCT
+TTTGTGGTATTTTCGACATGGGGTTCTTTCTGGCTTTCCTCATCAAGGGT
+GTCAATGTCCCGTAAAAATTTCGAAAACGGGACAACGGGACGTCCCGTTT
+TTTTGAAAACACTCAAAAAACGGGACAAACTGGGCGGTTAAAAAAAAGAG
+TGCATAGTTGGCGTAAATTTTAGTGTATTCGAGGCAAATTATAAAAAAAA
+CTGCATGTAAGTCATTAATCTGCATGAATTTAAGTCTTGAAACAAAACTC
+AAAAACAGAACTTTAAAATGTGCAACAAAATCATGAGAGAAATTGTCCCG
+TTCCCGTGATAATTTTGAAAACGGGACAGCGGGACGTCCCGTTCCCGTGA
+AAACACTCAAAAAACGGGACAACGGGACAAACGGGACACGGGACTTGACA
+CCCTTGTTCCTCATTAAAATTTTCGCGCTCCATTGATAATCGCCCTGGGA
+AAGTCGTGTACTCCACACGGACAAATCACATTTAGTTTTACAACTAAAAT
+CGAGAAAATTGGGAGAGTTTTTGCCGCGAACCTGGCCTAGTTCGCGGCAA
+AAACTCTTCCATTTCAAAATATGGGCGAAGCCAGAAATCCGTGATATTTT
+CAGCATATTTTTTTGATTCGAAGCAAATCTCAGTTTCTCACCACAACGAA
+CAACTTCACATTCGGATGCCGCCCGTCTTCGAAACGTGGAATTCCAACTG
+AATTCACCGATTCGACACTTGAACCGGGTGACATCATCATATTTTCAACC
+AGCTCATACTCGAACTCCGGAATATCCGGCACCACATCAATCGGTGCTGG
+TTCTGGCGGTGGCGGCTCAACTGACACTTTTCCTTGATCTAAAATTTGTT
+TTTTTCTGAAAATTTGTCACTGTACCAAATCAAAAAAAAAACCTTACCAG
+AACTCATAATTTTTGGATTTTAATTTGTAAATTGCAAAACAGAAAATGAA
+TTGGAATTTTTTCACTTTTTATTTATGGGAGGGGGAAATTCTTTGTTGTT
+GCAATAAAGTAAAACAATCACAGTAAATGCCAGTACAATAGTTTTTCACG
+TGTAATATATTAACCAATTACTATATTCAATAACTCTGTCGTCTAAATAC
+ATAGGGTAGGGGGGAAGGTGAGGGAAAATGGAAATAATAAAGTGAAATGT
+TTTGTGTACTTGCGATAAAACAATCAATAAATGGGAACAAGCCGATGATA
+AACTGATAAACCGAACGTGAATATCGAGAGAGGGAGGAAGAAAGCGTATA
+CCCGTTAATGAAATCAAGTTAATGGAATTATTTGGATTGAAACAAAACAA
+CGAAAATATCAATGTTTGAGCATAAGGAATGAGGGAATGGCACTGGTGGT
+GGTGGATAAATGAATCGGGGGGAACGGAATCTATGGAAGTTTCGAATACA
+TCGCATCGAGTTGCTTCGAGTAGTGAGCCTTCAGCTTCGGACGCTTGCTC
+TTCAACGTTGGCGTGAGAAGATCATTCTCGACGCTGAATTGCTCGGCGGA
+GAGACTGATATCGCGCACTTGCTCGAACGAGAAGAGCCCGGCTTTCTTGC
+CAACAGCGACCATGTCATCGAGGATCGCCTTTTTGACGGCGTCGTTGTTG
+CACAGCTCTTCGAATGTTCCCTTGATTCCTTGGTCGGCCATCGCTGGGAC
+GAGAACCTAGAAAAATTGAAAATTACATATATATATATATATATACACGC
+TCTCCTCAAAGCCGAATAATTATTAGAGCGCGCTTACTGCGCTTCGCGTT
+TCTGCATCCGCGGCATTTTGACTTTACACTGAAAAAAGCAGATATTTCAG
+ATTTATCGAATTTTTAGCTTTTAAAATTTTTTTCTGCATTTTTCGAACAA
+ACCTTTTGTTAAACAGTGAAAATTGAATTTAAAATGACTAAAATGAACTT
+TTTTCGTTCACTGGTTGTGAAATGGTTTGAATTTGAAGAAATCAAAGGGA
+TTTTTCTGAATTTTTTAATAATTTTCTATTAAAAATCGGTTTTAAACCAT
+TTTTTGACCCTAATGTTAAGTCACAAATGTATTGAAACCGGTTTTTAATA
+GAAAATATTTAGAAAATAAGAAAAATCCCGTTGATTTCTTCAAATTCAAA
+CCATTTCACAACCAGTGGACGAAAAAAGTTCATTTTAGTCATTTTAAATT
+CGATTTTCACAGTTTAACAAAACGTTTGTTCGAAAAATGCAGAAAAAAAA
+TTTTAAAAGCTAAAAAATCGATAAATCTGAAATATCTGCTTTTTTCAGTG
+GAAAGTCAAAATACCGAGGATGCAGAAATGCGAAGCGCAGCAAGCGCGCT
+CTAATAATTATTCGGCTTTGAGGAGAGCGTGATATATATATATTTTTTTT
+AATTTTGAAAATATTTAAAACCAAAAAACCAACCTCAGCATCAGGTACAA
+CAATAGCAATGAGACACGTCTTCAGTGATTCTCCATGAACAAATGATTGA
+GCGACATATTTCGAGCGGACATAGATGTTCTCAATCTTCTCCGGTGCCAC
+GTATTCTCCCTGCGAGAGCTTGAAAATGTGCTTCTTGCGATCCACAATTT
+TCAGCGTTCCCTCAGGAGTCCATCGTCCAATGTCTCCAGTGTGCAACCAT
+CCATCCTCATCGATCGTCTCCTTCGTTTGTTGCTCATTCTTATAGTATCC
+CTTGAAGATGATGTGTCCCTTGACACACACCTCGCCGGCTTGATCCTTCG
+CGTAATAGTTCAACTCGGGCACGTCGACCAACTTGATCTGACACGATGGG
+ATCACCATTCCGACGTGTCCGGCTAGCGAATCTCCTTCCATCGAGACAGT
+GCAAGCGGCGACACATTCCGTTTGACCGTAACCCTCGACGACGACACATC
+CCATAGCGGCACGAACGAAGGTGAGCACATTCGTCGAAAGTGGAGCCGAT
+CCGGTGATCATCAGACGCACACGCCCTCCGAATCCTTCGCGAATCTTTTT
+GAATACCAAATTGTCGAAGAATCCGTCATTTCTGATATTGAAGCTGGAAA
+AAAAAAGAAGATATTAAATACTATCAAATCATTCAGACCACTCACTTTGC
+CATATCTCTGGCCTTGTATGAGATAGCGAAATCAAACAACATCTTCTTCA
+AAGTCGACTTGTTCACTTCAGACATCACTTTATCGTAAAGCCGATTCAAG
+ACACGTGGCACCACTGGCACCACAGTCGGCTTCAACTCTTTGATATCCTC
+GGCCAACACACGTATGTCACCACGATAGAATCCGACTTTCGCGCCGACAC
+AGAAGCACACACTCTCGATGACTCTCTCGAGCATGTGAGCCAACGGAAGG
+AAGCTGATCATCGAATCGGTCGCCGCGATGCCACTGTGCTTGAAGAAGTC
+CATACAGACACCGTCGGCGATCACGTTCGCGTGAGTGAGCATCACACCTT
+TCGGTGTTCCAGTCGTTCCTGACGTGTAGCATATGGTCGCAAGATCCTCT
+GGTGTTGGTGGAATGTGTGCTGGACGAGTCTTGGCGTTCTTTCCAATCTT
+CTCGAGATCCTCGAACGTGAGCACCTCGACTCCGAGCGATGACGCAGTCG
+TTTTGAGCTCATCGGTGACTGGTTCCATCACAACAAGTGTGCTCAAACTT
+GGGCATTGCTCCTTGAACTTTAAGAGACCTGAAATCAAATTTCCTTTTGT
+TTTTAATAATATTCCTTATCAAACTCACCAGTGGCCTTTGAAATATCATC
+ACAGACAACAATCTTGATCTCTGCCTGATTCAAAATGAATATCGACGCTT
+CTGATCCAAGGGTCTCGTAGATCGGCACAATCACATTCGAATAGTTGTAG
+GTGGCGAATTCGGTGATGATCCATTCGGCGCGATTCTTCGAGTAGATCCC
+AATGTTCTCCGCGTTGCCAGTCGGAACGCCGAGCTCACGGAACGCGACGG
+ACACGTTGTCGGCTCGCTCGAGAATCGTATTGTACGACTCCCACACGTAC
+GGGATTGAACCATCCGACTGTTTGACTCGACGTCCGAGCATCGGCCCGTT
+GTTCGAGAGACGGGCTCCACGGCGAACACCCTGGTAGAGGGTGCGCGCGT
+CTTCGAACAGGAAAGCCTGGAGTTCGTCGTCCTTCAGGTAGGCGCTGATG
+CGGGAACCATCCTGGAAATTAACATTTTAGTCGGGGGGTTTTTTTGGAAT
+TTTTTTTTCGCTCGTTTTCTATTGTAAACCGAGCCACGACGCGACACGCC
+GTAAATCGACAAGCCCAAATGGCCTAATTCGGCAAAATCTTACATTTAAA
+AATATGAGGGAAGACAGAACTCCGTGATTGGAGAAAATTAAAGGAGGACT
+AACGGTTCGGACGATTTTGAACGTATAGACCCAAAATGAGCTCAAATGAA
+TGAATTTCGTAATGAAACTGCTCAAAAATTTTTATGGCGGTTCAAAATGT
+TGAAAAAATTACACTGATTTTGGCTAAAATCACGAATTTTCCCATTTTTC
+CGTGTCACATCTGTTCGAAGTTGGATTTTTTGGAATTATCGTTTTTTATT
+ACATATATTGGTAGTTTATCTCATTTAATTTCGTCGATTAAAGTACATTT
+AAAGCCGATAGGTAACCAATTTCGATAATTTTTGGTCACCTATCGGCTTT
+AAATGTACTTTAATCGACGAAATTAAATGAGATTAATTACCAATATATGT
+AATAAAGGACGATAATTTCAAAAAATCCAATTTCGAACAGATGTGACACG
+GAAAAATGAGAAAAATTCGTGATTTTCGCCAAAAACAGTGTAATTTTTTC
+AAAATTTTGAACCGCCATAAAAAATTTTTGAAAATTTTTTGAGCAGCTTC
+ATTACGAAATTCGTTCATTTGAGCTCATTTTTGGTCTATACGTTCAAAAT
+CGTCCGAACCGTTAGTCCTCCTTTAAGTTTAAAAAAAAAACGGCATATTT
+TGCCCAGTTTCTCTCCAAAACTCACCGGCAAAATGCGACTCTGATTCATC
+GGATCCACCAGTGGCTTGACATTTCCCGAATAGGTGACCCCACTGAACGA
+GTAGGATCCCGACGTCGATGACGAGCTCTTCGACAAGTAGTATCCGAGGC
+CCATGGTGACTGCGGCGGCGGCTCCGATTTGAACGTACGGTGGAAGGGAA
+GAGTTCGAGTTTGGTGCCGAAATGAAATCGACAATACTTCTGTAACAATT
+GAAATTATATATAGAGAGGACGGGTGATGATGATGAGTCATCCAGGTTGT
+TGTTGTCGCGCGCGCGCGCCCGCACTGTTCCCCACAAAACAAACAACTTA
+TTTGAAATTATGAAATCGAAGTTTCTTTGTTATTTTATTTTATTTCACAA
+GATGGTTTTCATGTTTTATATACCATTCGCAAAAACAATACCTAGTTTTT
+GCTCGTTTGGACTCAGAAATTTTGAGACTTTTCTGAAAAGTTTAATGGCA
+GATCAAAATTTCGGAAAAAGGTGAATTTTAGCGAAAATTCGCCGTGGTTT
+TTCGAAATTTTGATCTGCCATTAAAGGTGGTGTAGTCGAATTTTTTTATT
+GCTTTATTAGACTCAAAATTGTCTGAAAACACCGAATTTCATAATAAAAC
+TTAAATGGCCTAAAATTAGCTAAAATTTGAAATTTGACCGACTTGTCAAG
+CGGCTGGAAACGTTTTTTTTTTGAAATAACCGTCAAATTTTGAATATACA
+GTGCAATTATCTTGCGTTTTCAACTTTATTTAGGTACTTTAAAGTCGATG
+AACGGCGAGATTTGTTTTTAATTTTTCACGAAATCTCGCCGTCCATCGAC
+TGTAAAATACCTAAATGAAGTTGAAAACGCAAGATAATTGCACAGTATAC
+TCAAAATTCGACGGTGTTTTCAAAAAAAAAAAAACTGTTTCCAGCTGCGA
+CGTCGGTCAAATTTCAAATTTTAACTAATTTTAGGCCATTTTTTGAGCCG
+TCATAACTTTTTTTGAGGAGTTTTCAAGAAGTTTTATTATGAAATTCGGT
+GTTTTCAGACAATTTTGAGTCTAATAAAGCAATAAAAAAATTCGACTACA
+CCACCTGTAATGGCAGATCAAAATTTCGAAAAACCACGGCGAATTTTCGC
+TAAAATTCACTTTTTTTCCGAAATTTTGATCTGCCATTAAACTTTTCGGA
+AAAGTCTCAAACATTTTGAGTATAAACGAGCAAAAACTAGTCATTGTTTT
+TGCCAATGGTATATAAAACATGAAAACCATCCTGTGAAAAAAAAACAACA
+AAAACACTTGAAATTCGTAATTTCAAAGTTCTCCAAAAAAAACATACACA
+CACCTCGATTGAGACTGTACCCACGCAGCCGTGTCTGTGATAACCATTCT
+GTGTGTTTCTGTGTTTAAGTGGCCTATTTATAGTCTTCTGCCAAAAGACG
+AAACCGCTTCTAAAATGAGATTAAATTGAGGTGGAAACGACGACGACGAA
+GAGGTGGAAGAAGTGAGGGTGAAAATCGAAAAAACAAAGAAGAGATCAAA
+GTTATTCCATCTTTAGAACTTTCTCCACTGCCAGCAATTGATAATAATAA
+TAAGATTTTTATGTTGATAACTCTTTCGGTATCAATACAAAAAGGGGTGA
+AAACCCGCCTCGACAAGCCTTTCGATCAGGCCATATATTTCTTTATCACA
+CTCTCCGCACATTTCGGAACAACTTTGACCTCCCCGGCAAGGGGGCAAAA
+GTTTCGAGAAGTTGTGTTGCGCGCGAAGGAGATGGAGAAGATGGAGAAGA
+TAGGCAAACACGTACACCTCCTCAAACAGTAGTAGTAGTGATAATTGATT
+TGATTAGTGATTCGGGTGGGCAAAACGAGAGAGATAGAAAGAGAAAAAGC
+GAAGAGGACAACGAACACGTGTAATCAACCGTGTGCCAAAGTTCTCGCCC
+TTTGGACTAATTGCAGTTTTTTTGGAGGAAATTCAATTAACACTGAAAAC
+TAGTTCGTTTAAGTGTTTACGCTGAATGGGCCAGGTTTTGAGGGAAAACG
+ATTTTCGAAGAACTTTAAATGTGGGGTACCGAAATCTGAAAAATATTTTA
+AATTGACTCCAAATTTTCCCCTGACTCCGAATATCGATGCGAAAAAATTC
+AAAAAAAATTTTCCTGATTTTATATTTAAGCTTGAAATCGCCGAATTTCA
+TTTAGAAATTCGCATTGGAGCGCGCTTGCATCGTTCGATTTTTTTTTCGT
+TTATTTTATTTATTTTCGCCGAATTCAATGTTTTTAAAGCCAGTTTCATT
+CATTTTTGTCGAGTTCTCATCGAAAATTTTTTTGACAAAAATTAATGAAA
+CTGATTAAAAAATTAAATTCGGCGAAAATAAGTAAAATAAACGAAGAAAA
+TCAAACGATGCAAGCGCGCTCCAATGCGAATTTCTTTGGGCGCGAAGTTG
+AAAAAATGGCCCGGGGCACAAATGAAATTCGGCGATTTCAAGCTTATATA
+TAAAATCAGGGAAATTTTTTTGAATTCTTTCGCATCGATATTCGGAACCA
+GGGAAAAATTTGGAGTCAATTAAAAATATTTTTCAGGTTTCGGTACCCCG
+CCTTTAACGGATTTTTTGGCTTAAAATTGGAAACTCTTGGTATAAAACTT
+GTAGAAACACCGAGTAAACTGTACACGTTTTAGACGATAATTCAAAAGTA
+TCGAGGGAAGTATCCAGAAGTTGAAAAATTGCGAAAAACAGGTAAAATAA
+GGAATTCAACGCGTGAATTTTGCATTTTTAGACTGAAAATAGTGTGGTAT
+TTCTTCAAATATAGACGAAAATATCGACTCGCACTGGTTTTCGATCGATA
+TTTATAGGTCGAGTTCATTGCTATGCACAACATTCCGGGAAAACACGAGA
+TTTGAGGAATTTCTGAGCAACTTCTGAGTAAAGCCAACAAAACATTTTGT
+ACAATTTTCTTGTTGGTCTTGCTCAGAAAATTTTCAATCAAAAACCAATT
+GGAAATCGATATTTTCTGCTAGTTTTGAAAAAACACATGATTTTTAATCA
+AAAATTGTTAAATTCATGCAATTTTCCAAAGTTTTACACGATTTTTTCTC
+TGGAATTCACATGCTTTTTAAAGCAAACGGCCGTTTCTCGTTGTTGGCTT
+CCACGCGATTCCATAGAAACACTGGGGCACCAGAGAAACCGGGGTCGAAG
+CAAATGACCAACAAACAACAAACGGATGTGTGCTTTTTCTTCGTTTTCGT
+CTTCACGAGGAACCACCACGCAAAATGGAACTACAACTACGATTGATAAC
+GAAAAAAAAAAAGAAGAGATGATGATAGTTTTTGCAGCAATAAAAAGAGT
+GATAACAAGATACACTCTATCTCACCCACACCTTTCCGTTCAAAGATAAG
+GAAATAAGATTCGGGGGGTTCAAAGTGTTGGAGCCAAAAACGGAAAACGG
+AGGGAGCAATTGTTCGTTGAACGAACAATAAAAAACCATCATCTGCGTCT
+CAAAAATACACGTGTAAGTGAGCGAGTGAGTGAGTGAGTGCCGGGGAATA
+AAACGAGTTATATGACCAACACAACGAGCGACGTTGCTGCTGCGTTTCCT
+CACTCTCTCCTAGTGAGCGTGTGTGCGCACCACACTCACATGAGCGCATG
+CAAGGGTGTATGCGCAAGTGGTACATCGACTCGGTATGAGAAGGACAGAG
+CAGTAGTAAGGAGCACACGTTATGTTGCTCCACTACTCACTGTTGCGTAC
+CGTGTAGCCTCTGCGGGCCACCGCGGTGCAAAGTACAGTGGAAGGAGGAG
+AGTTGAAAAATTGGTGTTTATTTTACTTTTAAACTCGTTTTCCTCCGGAT
+TTTGAAGAGAATTGGTTGACTTTTTGAATTTTAGGCGAAAAGCGCGGGAA
+AAATCGAAAAAAGATGTGAAAACGAGTGAATTTTAGGGCAAAAGTGAACC
+GACAATTGTTATGAGCAATCGGGCTTCTCGGTCGGAAAACAGATCACAGA
+AAAATCGGAAAATCCAGCAAAATACTCGAAAATTATGCAATTTTCTAGAA
+TTCCAAGCGAAATTTTCTAGAATTTGAGGCAAAATGATACGGAAACCAAC
+GAGAAATCCAGAAAAAAAAACTATTTTCATCGAATTCTAGGTGAAAAGCT
+CTGAATTATTCGATTCTCCGTCGGGGTAGACTCAAAAATTATGCAATTTT
+ATAGAATTCTAGGCCAAACATCGCAGGATCGCCTACACAATTTCCGGAGA
+ACGATGAAAATCGGCAAATCTGAAGCAAATAGGAGTGAAGGAAGAGGCTT
+CGGATCAGTTTTTCTGAAGAAAATACAAAACTTTCGCTTTCGCAAAACTT
+TCGGGAAAATTCTCAGAAAAGGCGTCAAAAGCTCAAAAAATCGACGTTGC
+ACGATTTTCGACGGAAAAATAGAGTAAAATATCCGAATTTCTGCTTTAAA
+ACTCGAAAAATTGCCCAAAAATCCGTTTGTTTTCGCCAAATTTCTCCTAT
+TTGGGGGTCACAAGGCGAGCGGGAGCCGCCGACGACGAGATGAAGAGCTC
+CACAGAGCCCCTGAGCCAACAACACAACACTCACCCAAAAATATTGGAAT
+TCTCCGGAAGGAAATCGTCGTACGACGACGGCGGCGGCGACGGTGCCATT
+TTTCATGGGGAAAATTAGAACCTTGTTCGAATTTGTGATTTATTATCGAT
+TTTCTATGTGCCACGTGTGCCCTATTGCGTGACCCACCTGATTAGTTGCG
+CGAGTATTTTGTCAGTGCGGTCGACGATCACCCGAAGAATGGAGAAATTG
+TCTGAAAAATGCGAAAATTGGCTATAAAACGACGGAAAAAGAAATAAAAA
+CAAGTGAAATGAGGCCGAGAGGCAGGTGAATTGTTTATGCAATTTTAGAA
+ATGTGATATTTTGGCGGTGTAGATCGAAAAAAATGCGAAAAACACGAAAA
+CAGGTCGAGAAATTCGCAAATTTTCGACGACTAAAATTCAAATGCACAAC
+GTTCGCGCGCGCGCCGAAGTACGGTAGGTCCCGCATTTTTGCGCGCGCGA
+AATTCAAATTTTAATTTTAATATTTTTTCTTTCTTCTTTTCTTTGATTTT
+TTAAGAATATTGTGCAAAAAATTCGTTCATTTTTCGAATAAAATTGTTAA
+AAAAGACGAAAAAAAAAAGAAAAAATAAGACAATTTCTCGGTGGCATACA
+AATAAATACAAGTTATTGTTCGGGAAAAAAATCACAATTTTACATTAAAT
+CCAGGTTTGTAATAAAATCAATTATTATTTTATTTTCTTCCAAATCCGGC
+ACATGGATTTGGGCATCCGCTGGTCATGCAGCAGCCACCTCCACTCCCTC
+CGAGACACGCCAACGACTCGCCGGTTGAGATGGCGAGAAGCACGAAGCAA
+ACGACCATGACCTGGAAGAAAATGTGTGAATGTTAAGGTCTCTTAATATT
+CCAATAAAATTATTTGGTTTTTTTTTACCGGTGTTCTTGCCAGAAAAGTG
+CAAAAATTAATTAAAACTCTAATCGTGGCGAGACCCATCTTAGAAACGAG
+AGTATGCGCCTTTAAAATTGGGCTACCGTAATAATCGAATTTTTGCAATC
+TTGCAATTGTTGATTTCCGAAGAGCGTTAACAAGAAAACATTTGATAGAA
+ATGACACATGAATTAGGTAAAATTTGGTTTTTTTTTAGATTCTTATAATT
+CAGATTTCTATTTTGGACACGGAGTTCTGGCCTTCCTCATTGAATTTTTC
+GCGCTCCATTGACAATCGCCTGCCGGACAACGAGTGGGAAAGTTGTGTAC
+TCCACACGGACAAATACATTTAGTTTAACAACAAAAATCGAGACGCGACG
+CGACACGCAACGCGCCGTAAATCTACCACAGATATGGCCGAGCCATAATG
+GCCTAGTTCGGCAAACTCTTCCATTTCAATTTATCGATGTCAGAGTGTCC
+CATTTCAGCTTGATCTACCTAGATCTACAAAAAATGCGGGAATAATACGT
+AGAGTTCTCAACTGATTTCGCATGGTTAAGTACGTGCTGACGTCACATTT
+TTTGGGCTAAAAATTCCCGATTTTTTTGTAGATCAAAAAACTGTGATGGG
+ACAACCTGACACCACGTGATTTATGAGGAAAGCCAGAAATCCGTGATTTG
+GAGAGCACAACAAAAAAAGAAATTCGGCCACTGATTCGCGGCCACGAGCC
+ACTGTGCCTTCTCAAGATATTAGTTAATAATTGACGCTGTGAGACCCACA
+GTTAAAGGCGCATGCTCAGCATGACTGGCCAATCTAATAGCATCTACAAT
+GATAATTGAAAAAAAAACTCACAGTTTGGCAAAGTTTAGCGACGAGTGAC
+ATAATTCTCCGAAAGCTTCAGCTGAACAATTTCAGGGATTACTTGCTGTT
+TCCCATCGCTTCACCGTCTTATATAGTGCCATCGCCGATTGGCAGAATGG
+GATACACCTGCCCCCAACTGCGCAGTTGAATACGATCCGTGTCTCTCTGC
+GTCTAGCGGTTCTCCACGATGTTTCTTTGGCGGCGGTGAAGCCGTGTGTG
+TGTGTGTGGCTCCTCCATTCTGATTGAATGTGTAACACTGCGGGCAACCG
+ATTGGTTTTGGCGGCGGCGGGAAAACGAATCCGGATATACTACATACACA
+AACACACACTCACACACACCGAAGGAACTTTTCAGAGAAACCTGAACTGG
+CTTTTTATGATTTAAGTGCTTCTGCTGCCAGCATGATGTGGTGGTTGTGT
+GTTGTCAATAGGATTTATGCTAATTCCTGACACATTCAAGAGATGAAACA
+TCAAACCGGGTAGGAACTTAGTCCACCCAACACTGTGAGAGATTAATAGA
+ACCTTTAAAAGTGGCACTTCTAGGCAGAATTCAATAGAATGGTGGGCGCC
+TTGGAGCCTAGTCGACCTGCGATGTGAGTGGCAAGGTTGGCAGAGCTAGG
+ATAAGCTTCTGGAACTGTAGGACTGTAACAAGCAAGGATCCCGCTCTGGT
+ACTGTAGTGAACTTTGAGATCAAATTAGGTTTTTCAATATTTAACTAGCA
+CTGTTTCCGGCCCTGATCTTAGAAAGAAAAGAAAAAAAGGATGTGAACCA
+GGCGTGGGCGGCAAACGATTTTTTTCCGGCAAATCGGCAAATCACTAAGT
+TGCCGGAATTTAAAATTTCCGGGAAATCGGCAAACTGACACTTTGCCAAT
+TTGCCGAACGGCAATTGCCGCCCACACCTGATGTATACATATATATGCTT
+TCACTCATGTGGTGCCAGAATGTCTCACTGCGGTTTGATCTACGAAAAAT
+GCGGGAATATTTTTCCAGAAAAATTGCGGCGTCAGCACGCTCCTAACCAT
+GCAAAATCAGATGAGATGTATGCGTCTCTTCTCCCGCATTTTTCGAAGAT
+CACAGCAAAATAGAACTTTCTAACTCCACGTGTCTACTGAGAAAAGAGCC
+GAAAGCTTATTTTCCACGTATCAGGGATCGGAATCCCACCTAGCTAGTTC
+ATCCTATTGCATCATTGAAGCATCTTCCGGATTCTCCACTTTGTTTGCTT
+TTCGAAATCGTTTCAAACTGAAAGCCGCGCTTTCAAGGCCGTCTTCTTCC
+GATTTTCCGATCTACCTTTTGTTGATCATCACGTGCCTGGCGATCACAAC
+ACTGTTCAACCGGAATATCTGAAGATGTTCCACCAAATGGATCGTTTTTC
+TCAGGACGGAAGAATACTAATTTGCAAAAAGTCTGTTCTGTTCTAAAAGT
+TCTGAATCTTCTGAAAAAATTTCAGACTTAGATCCTGTCATTACATGGGC
+AAGCAGTGGAGTCGGAGATTTTTTATCAAAATATATGGATAGGTAATCAG
+GGAGAGACTGGCTCCTTTGTTACAATATATTAGGTTTTGTTCTTTAAAAT
+GTTCAAATGAAGCTGAAGAGTTCCGGCTAAAAGTATATGATTTTTCAATG
+ATTTTTCAAAAATTTCAAGGTATAACTCTGAAACTAAAATTTAAAAAAGA
+AACTAAATTGGATTTTAATGTTAGTTAGTTTATTAACAGAAAGAGCAGTA
+TTTTTTGATAATTGTAACCTGAAAACTCTATTTTTCTAGTTTCGTGAAGT
+AAAAATGTTTTATTATGTGACATTTATTGAAATTTAATTATAATACACTG
+TTAGAAATATTTTATTATCTAAAAAAGTAAATTGGATTATAATGTTAATT
+ATTTTACTATCAAAAAGATCAGTATTTTGTGATAGTTTTAACCTAAAAAC
+ATTTCTGAAGATCGTTTTTTGTGAGAAAAAATTATTTTAATATGTGTCAT
+TTAAAGCAACTTTTAAAAAATTGCGGTTTAGAAATGTTCAGCTATCAAAA
+AAAAGTACATTGGATTTTGGTGCCAGTCAATTTATCAACAGAAAAAGTGG
+TCCTAAAATAATTTCCAAACTTATTAATGGTGGTAGCATTAAAAAACACT
+TTTTTTTGGATTTTTTGAAATGAATAGTGTATTTACAGAGACAATGGTAG
+ATCAACCTAAAAGAACAAAAAATTTGCAATTTTTCCAGGTAGGACACTTT
+TTTGCTACTCGAATATAACTAACCTAAAATAATTTCCAAAAGTTTCAATG
+GTGGTAGCACAAAAAAAAACAATTTTTTTGATTTTTGAAATGAATAGTGT
+AGTTACAAAGACGGTGGTACATTGACCTAAAAAAACGAAAAATTTACTAC
+TTTTTCAGGTAGGACACTTTTTTGCTACTCGAATATAACTAACCTAAAAT
+AATTTCCAAACGTTTTAATGGTGGTAGAATGTAAAATAACTTGTTTTTTT
+TTGGTTTTTTGAAATGAATAGTGTAGTTACAGAGACAATGGTACATTGGC
+CTGAAAGAACAAAAAATTTGCTATTTTTCCATTTTGACCAAAACTATTGG
+TTTTGTCCCCAAAAAATTAGTAAAATGACCCACAATCCAGTTATTTTGCT
+GTTTAAGCAGACACACTACACGGAATTATTTTCAGAAACCAGATGTATGT
+TAAGATTTTAGTAGTTTCGGTGCTGCAAAAACCATCAAAAAATACCAAAT
+TTTTCGGCGTTTGTGAAGCACGGCAATTTTTGAGATTTGCCGCACACCCC
+AGGTACAGAGACAATTTTATATCGACGTGAACGAACAAAAAATTTGCTAT
+TTTCTCAGGTAGGCCACTTTTTTGCTGCTCTAATTTCACACACCTAAAAT
+AATTTTCAAATGTTCATCCTACCCTTATATGTAGTAAGAAGATTTCAAAT
+TCAAATTTTCATGCATCAACTCGTCCCCACCGTTTTTGTTTCCCTGGCTG
+ACTCATCTGACCTTGTCACCCCACGTGTGTTTGTCTTTGTGCCCCCTCTC
+GTGCTCACCTTGTTCCAAATTCTGTGAAAACTCATCTCGAAGGCCATTTT
+CTTCGTTTATGAGTTTTGAAAAAAAAACGTTCAGACAACTGCAAATGACC
+TCCCCGGCGTCGAGAATCGGTGATAACCTTGTACTTCTTAGATGAGACCA
+GATACAAAGTGCACCAAAAAATTCAAATTCGCTTGAGAAGCGCTGGCGAG
+AGATTCGAAGCGAAAACGAGTTGATTGACAATCGGAACATATACACACAC
+CAGAAGACAAAGTGGGGGAAGAAAGGAAACAAAAAAGATAGAGAGGAAGG
+AGATTTTGAAAAACGACAATCTCTCTGTGTGTGTGGGTGACAGGTGAAAA
+AGTGAGAGTGAGAAAAACGTGGTGGGTACTGTATTGATGAACGATCAGAC
+CAAGTTGCATTCAAATTTCTTTGATTGGATTGTTTCCTGATCGGTTTGGT
+AGAAGGTGAAGTTGGATTTTGTTCACTGAAGTTATTGGATTTCGAGACAT
+GAGCAAGCTAGGTTCAGGATGACTGTAGTGGCCGGCTAACTTTCCGTACA
+CCTTTGGCCGACTAGTGAGTGCAACCAGGGCTAGTAAGGAGGTACATCCT
+GGTTACCGTAAGCTTATTAAAATTCTGAAAACACCCTACAAAAACTGATA
+TTTGTAAAGTTCTCCAAAACAGGTGCTAAAACTTCTGAGGCAAGAGTAGG
+CACTTGGAGTCAGAATGTCTTATTTCGATTTGATCTACAAAAAACGCGGG
+AGTTGAGACGCAGAAATCTCATCTGATTTCGCATGTTTAAGAGCGTGCTG
+ACGTCACAATTTTTCTGGAAAAATATTCCCGCATTGTTTGTAGATCAAAC
+TGTAATGAGACAGCCTGGCACCACGTGGGTAGGTGTCGGGATGCACGTGG
+TGTCAGAGTGTCTCATTTCAGCTTGATCTACGTAGATCAACAAAAAAAAA
+TGCGGGAGAAGAGACGCAGAGTTCTCAACTGATTTTGCATAGTTAAGCTC
+GCGCTGACGTCACATTTTTTTTGCAAAAAATTCCCGCATTTTTTGTAGAT
+CAAACCGTAATGGGACACCCTGGCACCACGTGGGGATGCATTAGTATGAT
+TACTGTAGATAAACCTTGAACAATATATATACATTAATTTCGTAATGCTT
+GAAACTTGGACCCAAAAACTATCTGTAACTAGAAAATCTGCAAAAATGAG
+TTTGCGACTTAAAGCTGGAAGTATACAAGTTGCGCAAAGACCTTTCCAGT
+GGCTTCAGCTAGCAACAAAAAAATTTGTAAATTTGCCGGTCCCCACACCA
+CATCAAACGTGCAAGACGGGCAACTTGGTACATCCAGTTCACCTGCACTC
+CAACTACTTCCCAGAACGCCACATAGTTGAATTATTACCCAACTTGGTAC
+ATTATTTTGTCGACTCGACACACCATCACCCCACCATAAACCCCTGCAAA
+TAAGGAAGCCGATCGCTATCTACTCATCTTTAGGGACCTTTTTTGCCGCT
+TTTTATTGATTTGAACAAAATCTCAGCAGAGCAGTCAAAAATTGCCAATA
+TTCCAATTTTTCAGTTGCCAAAGATTTTAGAGTTTCAATACCTACTAAAT
+CCTCCCGTTCCAGCCATCCGTTCTTGATATTCTCTCCATAAATTTTCGCT
+TATCTCCTCTCTTGTAAAACTAACGTTCACTTATCCACATAATAAATACA
+ATAAATGTATTATATACATATATATTATATATATATATATATATATATAT
+ATATATATATATATATATATATATATATATGTATATATATATCTCAAAAA
+ATCAAACAGGATCTCTCTTTTCCTCCAGGAGAAAAAGAAGATGCCGTTTT
+GCAGCCAACAATACTCTCACTCTCAATACACGACGCGACGACGTGGCATC
+CCTCCCCCCATCCTGCCTTTCTTCCCCGTTTCTCCTGTGTCATCGAAATT
+TCTAGGGCAGCAGCACACCGGATTGGTTGGCATGTGAAGCCGACGTGGAT
+CGTGATGGTGATGATGTGGCGGATTGTGATAGATCGTGTTTTTTATCCGG
+CGATTACTGCGAGAATTGTCTGAAAGAGTGGCAGGGCCTGGCGCCTGTCT
+TTCGGCTCTTTTCAGCATTTTGACGTGAATTTCCAAATTTCTAATTTTCT
+CATTTCTATAAATTTGCTGAAAATCAATCAAAGAAATAAAAAAAAAGTTC
+ACTCATGTTTTAGCATACGGCGCGAGAGGCAGGCGGAAATCGCCTTAAGG
+TCAGGCAGGCAGGCAGGCGTTTAACGCCTACATGGAAGCCCTATAGCACA
+CATCTATCTGAAACTGGGAATGTTGTTCCGAAGTGCATTGGAGTGCCTGA
+AATTATACAATGTTTGTTCTAATTTATCATTTACTGTATATAAAGCGCTT
+ATTCCGTGTGTCCATAGTTGGTAGTCTATGTAGTCTGAAGTTTTGGCTTC
+TGGAAGGATAGTGAGTTGGGGTTAGTGTAGGGATATGGTCGGGGAACTGT
+AGTGGTACAATAGCGGTACGGTAGCAGTACTGTAAGATTATGGTACTTTC
+AGAAAAAAAAGTTTTCAGCCCCAGAAGTCGGGGTCCGTGCCGGAGGAGCG
+GACAACGGCTGGTTATCAATAAAGAATACCAACATTTTATCACAGATCCG
+GTTACCGCTAGACAAGAAGGTAAAAATTCGCATTCTGAGAAGGACTACTG
+TAGCAGGTGTTTAGCGTGTGTCCGAGTAGATGTGGCGACTCTTAATTTAA
+GTTGTAGTTTCCTGGTGTCCCCTAATCGCGAACTTCACGATAATTGTAAA
+TATTTTAGTGTGGCCTATGTTTACAGGTTTTACGGACAGCCTAGCCCGAG
+AAAAACTCTGGAAAAAAATCCCAAAGCTCTTATCCAAAACTACCAAAGTA
+TTCTATGCAATTCCCTTTTTGCATTTCCTCACCCCGCCTAATAAGGCATG
+TTGTTTACCGCCGACTTTCCGCAATAATCTATTCTCGCAATCATGTGATT
+TACCTGACGAATCGAAAGTATACGGTAACCTTCACATTTGGAAGAGGAGA
+AAGGAATTCGTTGGAGCCTTGACCCATTCTCCCCACAGGCATAATTCAAA
+AAAATATTCACATCAAGAATGCGGATTTGCCACAACCCAACGGGTTCTCC
+CATCCAGCATCTCTACCTTTGCCGAGGCAGAAACTGAGGACCGATCTCGA
+TCTGCCGCCGCGTTCCGACAAATGTAATAGCAGCCCCCCGCGCGATAGCT
+TTTCACTTTTTCTTCTCTTTCTGGCTACTGCTGCTGCCTCCTCCTGCGCA
+AGGATGATGCTGCTAGGATGATACCCTACGAGATTACGGAACTATCCGAT
+AAATTAGCTTGATGGAGACTAGAGAGATAGTCCCGAAGCTCTGAAGGAAC
+CTGATCTTGTTACAGTCTTGGAACCGAACAGCTGATTGCGTCGTCGTATT
+ATCGTTATTCATTTCGTAAATAGATTTTCTCTAGGATTGATTCCCGGTTG
+AGCCACGTCACTGTCCGAGAACATTCCGGAATGTTATGCATATGTTCTTG
+TAAATAACCTTTCTCCTTCCTCCGGCCGGCCAACTACTTTCATTTCTTGA
+TGCGTCGAGATACGATATCCAAGGCCATCTTTCAAAATCGCAAGTTATCC
+ATCTTTTTTCGCTGATGACTCTCTCTCTCTCTACTCCTTCGCCCATCTCG
+TCTTCAGAATCACCTACCGCAAAACAATTGAATAAGTGAGTGTGGAAGTC
+ACGTCATGAGCGCGACGAAAAGAGAGAAAGAGAGAGAGAGAGAGAGAAGT
+GCCGAAGACGTCGGAAGAGAAAAGCTGGAGGAACCAGCGGCTGGATCGTC
+GTTTGTTGATGATGCCTCCTGCCTGCCATTGTTATTCGATATTCCGATAT
+TCGATTCTTTTTTGCCGCCGCCGCCCAAGAGGAGAGGAGAATCAGAGAAG
+CTTGCGCGCTCCCTATCAAAAAAAAAAGATTATCAAATTTGAAGCAGCAG
+AAGCTGGGAAATGGAAATAATAGCGGATAAACAAAGAGAGCGAAATGTTT
+TGGGCAATAAATTTGTAGTTTGATGATAAGAGTGGCATTTTGATATGAGG
+AAGCTTGCAGAATCTAGTGGTGAACAGGAAGCTTTCGCTATGGAGCAAAA
+TGGATTCCGTCATTTTTCTTAAAGAATCGGAGTCGAGATGAAACACCCAG
+CCGGAGCTGAAAAATTATTCTGCTGAAAAATCGAGGTGCTTGAAGTACCA
+GGGCGTTATACAAAAGATCCAGGGATCCTAGTTCTGCAAAAAAAATTTCT
+GCATAATGAAATGGAGAACAGGGCGGTGCGGCAACCAAGATTTTCGGCAA
+CCGGCATTTGCCGAAGTTGCGGAACCCAAAACATTTTGGTAACCGGCAAT
+TGCCGAAGTTGCCGAATTCAAAAAATTTCGGCAACCGGCATTTGCCGAAG
+TTTCCGAATTCAAAAAATTTCGGTAACCGGTTGCCGCACAGCTCTGATGG
+AGAACCCGGTGGTCAGCTCAGAGTTTGGATCACCACAACCCAGAAATACC
+ATCTTTCAGTGCCTCATACGTAGAAACACTCTAGCTCAAAGTGCCCCTGA
+GGCCCTGGGATCTATCCTTACCTGGAAAACTGTGTAAAATTTCGAATATT
+CACAGATCCTAGGTTCGTAGTTTCACAAAATGTTCCCACTCTGCCTTCGG
+ATCCCCAGGACGCATTGCTACAATATTTTGCACTTGGTACAGTACTCAGC
+TTTCCCTTTTTGCACCAAAAAACATTATTGATCCTTACGATTAGCGTCCT
+AGATAGGCTACAAGGCCATCGAGATCTCAAATATGCAAATTCTTAGGAAA
+GAAAGTGATGTTTCATCATCTTCTTGGATTAAAAATTTCCGAGGAAAAAC
+ATGGCAAAAATCAGGTTGATCGTGAAACTCGTCGGGGGCTCCTCTCACTT
+CTTCCCCATCTTCATCTCTCCTTCTCTTTCCCGATCCGATCTTTTTTCCT
+TTCTTCCATTTTTTCTCGTTTTTCCTTTCCATTTTTTCTTCTCCTTCTTG
+TGTTTGATTATCCATCCTCCTTGCCCTTTCTCCTTGTTTCATTTTTCTTT
+ATTCATTCGGATGGAATAGAGATATGGTTCCGTAAATTCATTCCAATACT
+AGAAGAATTAGTAAGACATTCGTAGGGGGGAAAATTCCGCGCAGAAAGCG
+ACAGGAGGTTCGGGATTGGGTAATCGTCGGAAAAATGAAAAATCGCGCGC
+GCCCGCCCGCGCAGATGGGATATATACTAAATCACATGGGCAGCGACATG
+ATATACGATGGATTGCGTGATCGATAGGCTTTTCAAGGAGGTACATTAGC
+ACTGGTGGGCGTCGGGATCCTTGAAGGAACAACGATCTTTGAAGGAGATG
+ACGAGGATGTTGTGAAATTTAATTGTGATATCATTCTATTATGTAATCCC
+TGGCCTAGAATATACATCATCTTTTAGAATTCTGGTCGGCTAGATGTTTT
+CGGGAAGTGCTTCTAAAGGATCGGCGCTGCCATGTATGTAGGAAGTGCTT
+ATGCCAACCCCAATCATCTTCTCAATCTACTCCTCAGAAGTTCAGTTCTG
+CCAATCCGCACGCTCCACCTTCGTCGCCTATCCGTTTCTCATGCGAGTCT
+CGGGTCAAGGCAAGTGTGCGTGTCCTTCAGTCGTGAAGTCCTATTCATTT
+ATTTTTGCTGCCAAAGTCCGAACAGTTTTTTCTAGCCGTGTCGGCAAAAG
+GGTTCTTATTGCGAATTCACCTCCTCCCCACTCGAGAAATCGCCCCCCCG
+CCGTCCTTGGTAAAACTGACCTAGAAAAATAAAAACAACACAAAGCGCCT
+CCCGCATCATCACGCGTATATATGTATATATATAAGATGGTAGGCGGGAA
+GAGGAATCGACGCAATATCGACTGAAGGTTGCGCAATCGAGATGGCTCTT
+CCCGGCACGGATACCTCCTCCTCGCGTACCAGGCACCCGCATATAGCTAA
+AGTTCTCCGCCCATTTCGTTACTTTTTTGTGCTTCCCATATCATCGCAGC
+AGCGCTTATGCCATTGCGCCCGACCCGATCCAACTTCTTATTCTTGTTCC
+TTAGCCTTCTCCCCCTCCCATGTCCTCCCGATATCCAAAAAGTGGGAGGA
+GCATGCCATAGTGAGAGGGCGGGGCCGGGACACACACAAGGCTGGCCCCG
+AGAAAACGAACAACACTTATGCCGAGGACAGTCTCGACAGTTGGTGGTCA
+CCCCACCTGCGCCTTGATTACCCCGCCCGTCCGCGCCCGCCGGGCTAAAG
+TATTTTGTTTGCCATTCATGTTCCTCATTCGACGTTCATCATGCTTCTGT
+TATGCTTCTTGGTGTTGGTCCGGTTCCTTTCTCTCTCTCTCTCTTTCTTC
+CTTGTGGATCAGATGCCATTCCGCCTTTTTGCTAGATAAGCGCATATTCA
+TCTCACTCTTCTTTGTTTTCAATTCAGCATTCTTTATATATCCAATATCC
+TACATCCTATATCCTCGTTCTCTCCTCATTTTCATTCATATGCCGATCCA
+TTTGGTACTGGTGGTGTCGTTCTTCTTAGTTTCGCTTTCCAATTCTTTTC
+TAGACAATTCCTTCTATTTCCAGAAACTTTTTTCTACACAATGCTCCCAG
+ACAGCCCATCCCCACGCGCTGCCCTTGCTCTCTCCGATCTTCAGCCACAA
+ACCGGCGCCTCAACGTTCTCAATTGGCAGTGGATCAGGCAACTGGTAAGT
+CGAGTTCTTATGTAACTAGTAGGATGGTAGACATCGAGATTAACGATGTC
+TGGCATTCGTTACGTAACGAACGGGTTCTCCCGCCGACCATCGAAGCGCT
+TAAGCGCCGAGATTCTCGGCTTCATCGCACCCCGGTCTAGCAAGTTTTCC
+AATCCATCCCAAATTACAGGTCGACAAGAGGTGTTGGTGGAGTTAATGGT
+GATTACATGGACAAATCCGGCGGAGGAATGTTCGGAAACAGCAGAAACAA
+CGTGAGTTATAAAAATATCTGGGGGGGGGGGGGGGGGGGGAAGTGTTGTT
+CTAGGCCAGGGACATTGAGAACCGCGTGATGAAGAGTACTTTTATCCGAA
+TTAAATCATAGGCAACGAAAACAAGAATCAGGTTCTTGTGCTTTGCACAC
+CATGTCGGAATATCCGTCTCAATCAAAACGAAAAAAGCCTAAGCTGGACC
+AAGTGTTAAATGCTTAAATGCCAAAAATGAACAATCTTTCAAATCACTTT
+CATCTTCCTGTAAATCAGAGAATCCTGAAGCGCTGGCGCGCACACTTACG
+AAAAGTGAAAGCCGATATATCAAGTTTATCACCTAGCGGGACTTCCATTG
+TCTCATTGTCTCTTGGCTATCCGCCCCACTTTCCCCCCGGATCATCCGCC
+CCCTTTAATCCAAGACTCTCGAACAGTTTCGCTTCATTCCAGGACCGATT
+CGCATTCGGCAACAACAGCTCGTCGTCCTCATCAGCAGGCTGCTTTTCAT
+CGAACAATTCGTCAGGCGGACTTTTTTCCAGTAAATAAGTTAATATGTGA
+GTTTTTTTTGTGTACATTTTCTTCTTTTCAAGATCCATTAACATTTCAGA
+ATGCGATCGGCAGCCGGTATTCTTATTCTAATCTCAATAATTATTCCCAG
+TGTATATAGTGAACCGAAGTTGCCCGATTGCGAGCAAATACCAAAAGTCT
+TGTGCTGTACCCAACGTGTCTTAGATAAATGTATGTCTGGTTGTATCGAT
+TATGTCACTGAGAAATGCCCCCACAAATTGGAAAAATACGAGACGATCGA
+TGAAGAGCCATCGACGAGAGCTCCAAAGAAGCAGGTGAAGCCAGCTAAGG
+CAACTAGCAACAGAGTTGTCGGAGCAGTTGAAGTAGACCATGAAGCCAAG
+GAGCAGTTCATCGACTCCAAGGATATCAGAAGAGCACCACGAGTCGGTGA
+TGCCAAGCTTCTCAGCCAGGAGTACCCGATCACCGAGGTCACCGACGCCG
+ATCTCTCCTCCGAGTGCGGAACCGAGAAGTCTCAGCCACCATTCTCACCA
+TGCTTGTCCCGCAAGTCGGCCGACGACGTCTTCCTCTCCTGCTGTCGCCA
+ACAGGTTCCATCCAACTGTCACAGCCTCTGCACCTACGAGCATCGTGAGC
+ATGTCGCCGCTGAAACTCTGATCCAGGCGATCCAGCAAGAGCACTGCGAT
+ATGAAGGTAAGAATAGTTCAATCTTCCTATTGAGTTTTTTTTTTGAGTTT
+TTCCAAAATTCATTCTTTCAGTACTTCTCCAAACTGCTCTACTGTGCCAA
+CCAAAACCGCGACAACCGCGCGTGCTGCTCCAACCTCGGCATGTCAAACG
+CGGAACTCGGCGTCGGCGATCGTTGCCTACGTATGTGCAACATCTCCCCG
+TCGGGAGACCGTGTAAGCTCTATGGAGAAGGAGGATCTCGTCTGCCTGTC
+CAACTGGAACGTCATCATGTACTGTGCCAGAGGTGGTCTTCGTACCATCA
+ACTAGACCATCATCCCCGTTCTCTTCTCCCGTAATAAGCTGGCTCAGGTT
+GTTAATAATAATTCGCCGCTCGTCTTAATAATTTTCCATTTTCCAATCTC
+GTCCCCCCTTTTCAACACTACCACATTTCTCAGTGATATTCATCTGAACC
+GCCCGACATACATCAGTTCCTCATAGTACCTAACAGGGTTCAACAAACCC
+ATCCACACACCGTCCCCCCACGTAACACCCCCCCCCCCCCCACTTAAGGA
+CCAAGTCCTAGTTACTGAATGTGCAACATTATGGCCAGAATGCAATACTT
+GTCCCATCTGAATCCATGTTATTTGATAATCTATGACAGTATTATACAAC
+CCTTTTTTTTCAAAACACAAGCCCCCTTGAAAACGAACTCATTGTATGTC
+AAACGGTATCCCTTATTACACGATTAATTGTGGAGTTTGAAGCGAATAAA
+TCAATCAATTTCTCGTTGGGTCCCACAGCGAAATGACTATTACCGGTACA
+GAGAGTGTGGATAGTTAGAGAGTGACAGACATCCGGGACCCAATGGGGCG
+GGGCGCGCGGAAGAGACGATTTGTGTCGATTTACGAAATGATGACAACGA
+GGAAAATTTCGTAAATCGACACAAATCGTCTCTTCCGCGCGCCCCGCCCC
+ATCGGGTCCCGGATGTCTGTCGCTCTCTAACTATCTACACTCTCTGTACC
+GGTAATACTATTGCAGTAATCGCAGGTTATTTCATAGCGATTTTTCATAG
+CTTCACGGATTTCTGGATTCCCTCATAAATTGAAATGGAAGAGTTTTTGC
+TGAACTAGGCCATTTTGGCTCTGTCATATCTGGGGTAGATTTACGGCGCG
+TTGCGGTTCGATTTTAGTTGTAAAACTAAATGTATTTGTCCGTGTGGAGT
+ACACGACTTTCTCACGCGTGGTCCGGCAGGCGATTATCAATAGAGCGCGA
+AAAATTCAATGAGGAAGGCCAGAACTCCGTGCAGCTTTACTCGCGAATTC
+AGGTGTGTGTTTTAATTGTCTTTATTCAGTTTTCTGATAATGAATATACT
+TTTTTACAGAAAAACTGGAAAACTGATAAAAAAGTCCCCAGAAACTAGAT
+ATTGAAATTACAGTACACTTTAAAGGCGCACACATTTTCACAGTAAACAA
+AAAATTTGTCGTGCCGAGATATTTCATCCAGATTATCAGTTGTTAAAATT
+TGACAACACTCATTTTGAATATTTAATGAATTCGAATGGAAAATAGAAGA
+AAGCTGCCAAAAAGTGAAATTAAATTCTCAAAAACTTGATTTCCAGACTT
+TTTTGGCGATTTTCGACCAATTTCAGCAGAATTTTTAGCAGAATTTTACA
+AATTTTTTTATTTTAAAGCTTATTTTAATAATTTTTCTCTGAAATATATG
+AATATCTTTGCTTTCGATGGATCTTCCTCAAAAGTAGACACACATTTTTA
+TTTTTCTACAAAACTGTGCAAAGTTACGTCGTGGTGTTTGCGTACCTCGG
+CGGGAATTTAAAGAGAAATGGCATTTTTCACTTTTCTCGCAGTTTTTCTG
+ATTTTTTTTTCGTTTTTTCGTAGTTTCCTAATAAAAAATCGTTCCAATTG
+TTTCCAGGTAATGGCTGGATTTGAAATTCAAAGAGTCGAGTCCAAATTCT
+TCGACTTGGACGACATAATCGCCAAGTCAGACTCCACGTCTTGCACATTT
+GAGATTGGAGATTTGAATCCAGGTCTGAAATCGCATCGAAAACCTAAAAA
+TTCTAGTGATTTTTGTTCAGATTTCTTCCAGGAAATGCTGGGAGTTTCGA
+AGCCAACTCAAAATGCAGACGGATACGGCGTTGATGCTCCATACTGGCTG
+CTGGAATCCGTTAGAAGTTCATTTTCCGTGAGAATTTAGTTAGATTTGCC
+CCGAATTTTAATTGAGAATTCCAGATTCAACTGCCAAAAGCTTATAGTGT
+GAACATGCAAAATGTGCTGAACGCTGACAGCAAGAAATTGAATCTCTCCG
+GCTTGCAGCAACACTTTTACGGCAACGGGATGCAGTTATGCCGTCTGATG
+AAGGGCGAAAATCCGGACGGCGCGCTGAGCCTCGCACGATGCCTTGTCTC
+CACACTTACACAGCGATTAGGAGGTATTAATTAATATAATAAAGCACTTA
+TAAAATACAATTTCTGGTTTTTTTTTGTTGCAGAAATTGTGTCAACTGCA
+ACCCATCTGCAAAGCAAAGGCGAGAAATTTGACAGCCTCGAGACAAAAGT
+GTTCCTGGAGGGTAAACGGTGCAAAGAAGACATTGATACTTGGCTGAGAC
+AAGACAATAAGTGCTCGAGCAAGAAGCGTAAGAGACTTTCGTTATAAACT
+TCAAATTTCTTATGCTTGAATCTAATTTTATTTTTTTTAATTCGTCTGTA
+AATATAATTCAAACCCACCATTCTGTAATAATATTTTATTTTCTATTTTT
+TCACACTCATTTTTGTGTTTTATTGGTGTAATAAACCTGGTTTCATGACT
+TTTTTGCAAGGAATTTTGTTGAAAAGGCTGCTGCAAAAACTTTGCCAGCA
+AAAAATTTTGTGCAAGCACGCTCCATCGCACAGTTTGAACGTCGCGGGTC
+GAAGTTAGATGTGCAGGTCATATAGCAAAAAGAGAAACACCCCTTTTTTT
+CTCGAGAAGTTTCACCAATTTTGCGCGATTTTTCAACTATTTTTTTGCTT
+TTTTGGCTTAATTTTGGCTCAGATTTTCCTCAAAAACATGAAAATCCAAT
+CTAGAATAAGTAGTAATGGGTATATTCTAAGATTGTGCAAAAGTTAGCTT
+GAATTTCCTCGATTAAAGCTTTCCTACCAAGAAAAATGTGTGGATATTTT
+GAATTTACAAGTTTTTCATCTTTTTTTTGTAATATTCTCTTTGAAACTCC
+TGTTTCTCTCAAATTTGTAAACTTTCATAAACGTTTTTTTCAGGGTTACC
+ACATTAAACAATGACCGGAAGCACCGAAACTCGCCAGAAGGAAGTCAAGG
+AGGTTGGTTGTTCAAAGTGACGTCTAAAATATTTAAATTTCTATATTTCA
+GCCACAAGTTGACGTTTCGGATGATTCCGACAACGAGGCCGTCGAGCAAG
+AGCTCACCGAGGAGCAAAGACGTGTGGCCGAGGCTGCTGGACTTGGAGAT
+CACATCGACAAGCAGGCCAAGCAAAGCCGCTCCGAGAAGAAGGCCCGCAA
+GCTCTTCTCCAAGCTCGGACTCAAGCAAGTGACTGGTGTCTCCCGTGTCT
+GCATTCGCAAGTCGAAGAACATCCTCTTCGTCATAAACAAGCCAGACGTG
+TTCAAGAGCCCAGGATCTGACACCTACATCATCTTCGGAGAAGCCAAGAT
+CGAGGATCTCACCCAACACGCCCAGATGTCTGCTATTGAGAACTTGAAGC
+CAACTCGTGAGGCCCCACAACTCAAGACTGTCGAAGAGGACGAGAATGAG
+GATGTTGAGGTAATTCAGTAACTTAATCGGATTTATTACATTAATTGTAC
+GGTTTAAGGAGGATTCCACCGGCATTGAGGAGAAGGACATCGAGCTTGTC
+ATTTCCCAAGCCAACACCACCCGCAACAAGGCCATCAGGGCGCTTAAGGA
+AGCTGACAATGACATCGTCAATGCCATCATGAGCCTTACCATGTAGCTTG
+TTTCCTGATGACCTTGCAGATACTCTTGTTATCGTTGTATCTCTTGCTTA
+TCCCGTTTTCCGTTCCAAGTAAACGTTTATCAGTCTTTTTTAACTTTTTT
+GTTATGTTTAAAAAACAATTGCATCTTCGAATTGACCTACCTTTTACAGA
+AAAGAACAATTAAATCACTGTTTGTGTAAAACACCCCTCTATTGATCGAG
+AACTTTCACTTCTTCCAATTCTTTACTCGTATGACTGTGATTCATTTCAC
+CTGCTATCACTTTATCATGACATTCCAGTTTATATCAACAGCAAATACCA
+ATTGTGTGTATGTGAAAAATGCTATTGAATAGCAAGCGCGCCCCAACAAA
+CACGTTTGAATGCGCGGGCGAAACGGCGTTAGATGTGCAGGTCATATGAC
+AAAACGCATCGACCAGCAGCCAATGGCAAGTTACTGCGAGCTGTTATAGA
+TTTTTTCACATGGTTTCCAGTGTTATCAGTTGGAAATCGATCGATAATAC
+TGACTAGTAGTACTTAACATCTTCATTCCCACCGTTTCGCTGTCATTTGT
+GATACGTGGATTTATTTTTCCTTTCTCGCCGACTTTTCATTTCTAAATCT
+TTTCTGGAATTGCGAAATTTTCAGCCAGTTTCATGATCGAATGGCTCGTA
+ATGAACCATCATCTCAGCAGCCGAGTAGTTCCGGGAGTAATGGAACTCCA
+GCACAACAAAACGGGTCGGCAAAACCATCAAAAGTCACAGTAAAAGGTAA
+CAATTCGTAGATTTTTTGCATCTGTTCTAATAATATTTCCCCCTCTTAAT
+CATAGTCGTCAACGCGTCGTTCACCAAGGCAGCCGACTGCTATGTCGAAA
+TCACGAGTGACACGTCATCGGCGGCGCCAAAAAAGACGACTGTAAAGAAG
+AAGACGATGGCGCCCGAGTGGAATGAACATCTCAACGTTCATGCAAATGA
+ATCTTCGACAATTTCGTTTCGTCTATTGCAAAAAGCCAAGCTATTCGATG
+ACACGTGTCTAGGGATGGCGAAGCTGAAGCTTTCGAGTCTCACAAGAAAT
+GAGAATGGAGAGTGTAAGTGGTTTTATTGAAATTTTCTCAAAAAATCTAT
+TATTTCAGTCAAAAACGACATCAACAATATATCTTTGCTGGCCAAAGACT
+CCTCGAAAATCGGAACTCTCAACATAATTTTCTCCGGATATCCAGAGCGG
+AAACGAAGAAGCGCAGGAGTACGAGCTGAAACCGCCGCGTCTGCAAGTTC
+AGAGGCATCCACGTCAAATGGCGTTGCCACGTCATCCTCGGCGCGGAGAC
+CGGCGACAGCGAAGCGTGACACTTTGGCGGCTCCAACGGTAATCGTGACG
+AGACCCATTTTGAATTATTTAATTATTCATGAAACGCTCTACTGGAGTGT
+TCATAATTATTAGAGCGCGCTCGCGCGGCACCTCACGAACTCCAGAATTC
+GCGAGGACAGCAGTTTTTGGCTATTTTGGCTTCTATGGAAATTATTTTTA
+ATTTTTTGATTTAAAATATTGTTGAGAAGCATCATCCAAATTGAAAATGT
+GTAAAATTATGAAATTTGACCGAAAACTGAAGGTTTTACAGAGAGGAGTC
+ACCACGGCTTTCTTTAAAAAGTATCAGTACCGTCAGTATTTCGATTTCAG
+AGTCGTAAAATATGTCATTTTGTAGAGAAACGTCTGTTTCACAAAAATCC
+ATGTTTGATATTTTAATTGTTTAATTTCTAATATAAAAATATTCAAAAAA
+TCAACAAGTTTACGTTAAAATCGAATTTTTCAATCGTTCAGTTTTTAATA
+AGAACAATTTCATAATTTCAAACATGGATTTTTTTGAAACAGACTTTTCT
+CTACAAAATGACATATTTTACGACTCTGAAATCGAAAAAACTGACGGTAC
+TGATACATTTTAAAGAAAGTCGTGGTGACTCCTCTCTGTAAACCTTCAGT
+TTTCGTTAAAAATAATTTCCATAGAAGCCAAAAATAGCCAAAAACTGCTG
+TCCCCGCGAAACGAAATCCCGCGAATTCTGGAGTTCGTGAGGTGCCGCGC
+GAGCGCGCTCTAATAATTATGAACACTAGAGGAGAGCGTGAATGAGCGTT
+TTTTATTCTTTTCTCTGCATTTTTAATGCTACAGAATCATACACAAAATG
+TTGTCAAATACATGCATTACTCTACTACTCTTAATGTTTACTTTTCATTT
+GCAGAGTACCGCAGCGGCGGCAGCAGCAGCAACAGCAGGCGGCACCCCGG
+CCGCCGGAGCAGAAGAACAGCTTCCCGATGGATGGGAGATGCGTTTCGAT
+CAATACGGACGCAAGTACTACGTGGATCACACCACCAAGAGCACCACGTG
+GGAACGCCCGTCTACTCAGCCATTGCCACAGGGATGGGAAATGCGAAGAG
+ATCCGAGAGGAAGAGTGAGTTTTCCGGCGGAAAAAGCAGATTTAGCACGA
+GAAAAGCGTTTCTGATTATATTTTTGATGCGAAAATCATCAAAATTAAAA
+ATATCTACCGTAGCCGCGGATACCTGGACCAAAATGCCGAAAAAAGTGAC
+CTGATAAATTATTTTAAGGCTAAAATCTTGATTTTTACATAATTAGTGTC
+TTATTTTTGTTGATTTCTTGTCAAATTTTTGTAATTGCATCGAAATAGGC
+CAAAAATAAAGTAAAAATCAACTTCCAACACAGAAAAACTGACAAAATTG
+AAGATTTTTGCTGAATTCAGGCAATTTTTCGTAATTTTGATCCTCCATAA
+TTTTTTTTTTCGAGAAAATTTTGAAATTTTTTCTTTAAATACGGCCTGAA
+AATTAGGAAATTATAACGACGGATAAAAAATTCTGATTTTCTTTATTTTA
+ACCAAGGTCTCCAATTATTTGATAATCGAAAAAAAAAAAACTTTCCAGTG
+ATTTTTACTTGAAAAATGTCTAAAAATTCACGCCAGGTGCACAATCCATT
+TTCAGGTGTATTACGTGGATCACAACACGCGCACGACCACCTGGCAACGA
+CCGACAGCCGATATGCTTGAAGCACACGAACAATGGCAATCGGGAAGAGA
+TCAGGCGATGCTTCAATGGGAACAACGTTTCCTTCTCCAGCAGAACAACT
+TTAGCGCCGACGATCCACTCGGACCATTGCCCGAAGGATGGGAGAAGCGT
+CAGGATCCGAATACGTCGAGAATGTACTTTGTGAATCATGTAAATAGAAC
+GACACAATGGGAAGATCCGAGAACACAGGGGTATGTGAAAATTTTCAATT
+TTCCAATAATATTTCTATCAAAAATCACAGTTTTAATGTTTTAAAAGTTT
+CAGAGGCTCCGACCAACCTCTTCCGGATGGTTGGGAAATGCGATTCACCG
+AGCAAGGCGTTCCATTCTTCATCGATCACCAGTCTAAAACCACCACCTAT
+AATGATCCAAGAACCGGAAAACCCGTCGGCCCGCTCGGCGTCGTCGGTGT
+TCAAATGGCCATGGAGAAGAGTTTCCGGTGGAAAATTGCACAATTCAGAT
+ATTTATGCTTGGTAAGGGAGGGCGAGAAATTCTTTGATTTTAGCTATAAA
+TTGATGTAAATTTCAGTCAAACAGTGTGCCTAATCATGTCAAAATCACAG
+TATCCCGTAATAACGTGTTCGAAGACTCATTCCAAGAAATTATGCGTAAA
+AATGCAGTCGATCTACGCCGGCGGCTGTACATTCAATTCCGAGGCGAAGA
+GGGTCTCGACTATGGAGGTGTCGCCAGAGAATGGTTCTTCCTGCTGTCGC
+ACGAAGTGTTGAATCCAATGTATTGCCTATTCATGTATGCTGGTAATAAC
+AATTATAGTCTTCAAATCAATCCAGCTTCATTTGTTAACCCGGATCATCT
+TAAGTATTTCGAGTATATTGGACGATTCATTGCCATGGTGAGTGTTTTTT
+TTTAATTGAAAATCAGTTGAAAATTGGATGAAAAATTGCGAAATCGAGAG
+AAAATCGAGTTTTCCGCTTTTTACAATTGAATTTTAAAATTTTAAACGTT
+AAATTTTGCAGAAAATTCCAAAAAAAAGCACTTGGATCTAAAATTTTTGT
+TTTTTGATGAAGGAAATCCTTAAATATCGATTTTTTTTATTTTCAGCTCA
+AAAAACCTGGAAATTTCGATGATCTCAAATTTTCAGATCAATATATTTCA
+TTTTCTCCTAAAAATGTTATTTTTATTTAAACAAATAGTTTTTCTTAGAA
+AATTCCTTTATTTTCAAATTTCCAGGCGCTATTCCACGGGAAATTCATCT
+ACAGCGGTTTCACGATGCCATTCTACAAAAAGATGCTCAACAAGAAGATT
+GTTTTAAAGGACATTGAACAAGTCGATTCGGAAATTTATAATTCATTGAT
+GTGGATCAAGGATAACAATATCGATGAATGCGATATGGAGCTCTATTTTG
+TTGCCGATTACGAGCTGCTCGGCGAGCTCAAGACTTATGAGCTTAAGGAG
+GGCGGTACAGAGATTGCTGTTACCGAGGAGAATAAGGTGAGATTTTGGAT
+TAGCTAGAGCTTATAAAAATAATTTTTAAATAAAATAATTTAATTTAAAA
+AATCCCAATTTTCCAGCTTGAATACATCGAACTGCTCGTTGAGTGGCGCT
+TCAATCGCGGTGTCGAACAACAGACAAAAGCCTTCTTCACCGGCTTCAAC
+TCGGTCTTCCCGTTGGAATGGATGCAGTATTTCGATGAAAGAGAGCTCGA
+GCTGTTGCTCTGCGGAATGCAGGACGTTGATGTGGACGATTGGCAGAGAA
+ATACTGTCTACAGACATTATGCTCCACAGAGCAAGCAGGTAGGGGAGAAC
+ATTTGATTAAAACTTCTTTTTTTTTAATTAAAAAATACATTTATAGGTAA
+CCTGGTTCTGGCAATGGGTTCGAAGTCTGGACCAAGAAAAACGTGCCCGG
+CTCCTACAATTCGTCACAGGAACGTGCCGTGTGCCAGTCGGTGGATTTTC
+CGAGCTGATGGGCTCGACGGGACCACAACTATTCTGTATCGAGCGTGTCG
+GCAAGGAGAACTGGCTCCCACGGTCGCATACGTGCTTCAATCGACTCGAC
+TTGCCGCCATACAGAAGCTACGATCAGCTCGTCGAGAAGTTGAGCATGGC
+GATCGAGATGACGGAAGGATTTGGAAACGAGTAGTCTCCCGTTGTTTTTT
+TTTGGTTTTGCTGGCCGCCTAATTATTGTATAACCCTCATATTTCTTCTC
+ACCCACACCCCATTGATTTTCCTTTTTTTTCTCTCCATCAATTAATGTTT
+CTTTTTTTCGAATTTGTGTGATAATTTTCGTGTTGTGATACCACTTGCTT
+AGGTTCTCTCTCTCTCTTTCCTTTCCTTCTGGGTATGTACCTATATTTAG
+AATATAGACAAAGCATCTAGTTTTTTTGGATTTAATTTCCAAATTTCCCG
+TTTAATTCCAACAACAAAAAAACAATTCCACCACTTTTCAAATATTTTTT
+TTGTGTCCATTGCTTCATTGCTTTTCTTCTTCTCAACCATTTCAACCACC
+ACCACCCAATCTGCGCCTTATTCTTACTTGGTCCTTGTCATTCTTAGTTC
+CAGTTTTTTTCACGGAAGCAGCTCTCGATTATTAATTCAAATGCATCCCC
+CCAACCAATCCGTCACCCCCCGATTAGAACAATTTCTACTTTTTTTTTTG
+AAAACAAAAAAAAACACAATTCCTCGATTTGGTTGTAATGAATTTAATTT
+TTTAAATTTTGAGCCTTTTTTGTTGTTTTAGGTTTTCTTAACTTTCAGAA
+TTTCCATGCGGAACACACGGAGAGCAGAAGATCAATATTTTGAACCCTGC
+AGGAGAAGGACGGGACCCTTTGGTCACTCATGTCTCGGCTGTCTGCGTCT
+CTCCTCTCTCTCTGCACCAGCGGAGAGGATGGATAGCCTCATTCGTTTTA
+TTTCGGACTTTCGATTTTTCTTATTGCTCCACGTTTTAGCTTTTATCAGA
+TTCGGGGAGCTCTTGCTTTTTTCTTGATTTTTTCGTAAAGTGTTCTTGGG
+TCCCGCAGCGAAAATTAACTTTAAAATGATTTTTTAAAAACTTTCTAAAA
+ATTCATTTTTTTTTCCATTTTACGACTAGAAATTTCGAAATTTGAAAAAA
+AAAACCGTGTTGCAAATGCGCTCCAGCGTACAAAACAAAACCGCCACCAA
+AAAATTTAAATTACTGAAAAAAACGATGAAATTTTGAATTTGTTTTGCCA
+TTTTCCGGCAATGATTTTTTAAATAAAAAAAACTGTACAACAAATGCGCT
+CCAGCGAACTAACCTTCAAATTACCGAAAAAAATTATAAAAATTTGAATA
+TTTCCGATTAACCCAAGAAAAGAAAAATTCAATGATTTTCTTGAAAAAAG
+TTATTTTTTTCTCAATTTTTCGTCAATAATACTCAAAATTTGAAGAAAAA
+TTGTGTAGCAAGCGCGCTCTAGCGAACCAAACAAAATGTCTCCATTGAAG
+CGTTTCACGAGGTTCTGGCCTACCTCATTGAATTTTTCGCGCTCCATTGA
+CAATCGCCCGCCGATAACGCGTGGGAAAGTCGTGTACTCCACACGGACAA
+ATACATTTAGTTTTACTACAAATATCGAGCCGCGACGCGACACGCAACGC
+GCCGTAAATCTACCCCAGATATGGCCGAGCCAAAATGGCCTAGTTCGGCA
+AAAACTCTTCCATTTCAATTCATGAGGGAAGCCAGAAATCCGTGATCCAA
+GTAAAAAAAATCCCAAAAATTTCAATTTGCAAGGGCGCTCCATTGAAAAC
+TGTGGCGCCGATCGCAACTCACGGTCGAATTTGAATTTTTAGTTGAAAAA
+AAAACACCAATTTGAACTGAAAATTTGAATTTTCAATTTTTTCCCTAAAA
+TAAATTGTTCAGAGTTTCGCTGTCGAATTGTTGATACCCGCTCGTCAGAA
+TTGGAAATTGAGAAATTGAGAGAGAATTAGAGAAGGAGAGGAAGAGGAAC
+TGCTCACTGGTCCCCTCACTCCATCCGAAATTAGGCACTTTTTGCTCCGG
+CGGCACTAGAAGACGAAGAAAAAACGACGAGCAGAACACAATCAATTTCG
+TCTTCTTTTTTATTTTTTTTTGGTTTTTTCTTGTTGGTACCACGGATTTC
+TGGCTTCCCTCATAAATTGAAATGGAAGAGTTTTTGCCGAAATAGGCCAT
+TTTGGCTCGGCCATATCTGGGGTAGACTAACGGCGCGTTGCGTGTCGCGT
+CGCGGCTCGATTTTAGTTGTAAAACTAAATGTGATTTGTCCGTGTGGAGT
+ACACGACTTTCCCACGCGTTGTCCGGCGGCCGATTGTCAAAGGAGCGCGA
+AAAATTAAATGAGGAAGGCCAGAACCCCGTGGTAAAACATGGTGCATCAA
+CGCAAAAATTTTTCATTTTTTGGAAAAACTCAATTGTTTTTTTTTCGCGT
+CGGGACCACCAAACCAGAGCTCGTTTACTAAATTGAATTTCCAAAAAAAA
+AAAAATTTCGCTCTGTTCAAAATTCGAAATTCAGTTTTCTTTCCCTAAAA
+CCTAATAAAATGATCTTGGCACAATGCTCACTGTGAGCTTTGGGTCTAGA
+ACGATGGCCTAGAAATGTTGAGATTTCCTCTTCCAGCGCCCTTGCCAATA
+TGACCTAGAAATTTCAAATTAGTATAACTCGGCCATTTTCCATCCGTTTT
+CGCCAAAACTACACCATTATAACATTTAAAACTTACTTTTCAATATGATG
+ATAATACTTTTCCAGTGGAAGAGTTTTCCGCATTTCTAAGCCACCAAAAC
+CTCTCCTCCCGACGTTTTATCAAACAAATGATATCACTGTGATTTGTGTT
+GTAAGTTGCGCGCATGATTGCACTTGCGCAATTAATTAAGACAATTACTC
+AAAATTTTGATCGAATTAACCCCATGTACATATAAAATACAAGATTTTTG
+TGTATTGTTCTTCAAAGTTTTTTGTCGTATTTATATAGAAGCAGTGTACA
+CCTAAATTTGGCTTATTACGACCTTTTTTTCCAAGGAAAATACTCATTTT
+TAGGGTTATAAACCCCTTGATTGATACGTGGCCTAGAAAACTGCAAGCGC
+TTTTTCCTGGAAGTTTTAGGCCACCAGTTAGAGTCTTGCAAAGACGGACT
+AGTTCTCACATGACCCAGAAAGTCTTAGTCCATCACGTATTTCTTACGAC
+GCCTAGAAATGCAAATCTTCGGCCACCAATTTTCATAGACATTCTAGGCC
+ACCCTTTTTGACGTGGCCTAGAATCTTTAACAAAATTTGTAATGAAAATC
+CTAGGCCACCATTCAGTTAGCTCTCATTTTTGATACTTCGCCTAGATTTT
+TAACACGTGGCCTAGATTTCTATTTTAACACGGGGCTTAGATTTTTATTT
+TAACAAGTGGCCTAGGTTTTTGCTACTAGGCCTAGATTTTTTACATGTGA
+CCTAGATTTTTATTATAGCACCTGACCTAGATTGTTGGCATTTGGCCTAG
+ATTTCTGTCATGTGACCTAGATTTTTTAATGCACCAAAAATTCTCCATAC
+AAATTTAACTCCTACACTCTAATTTGTAATCAGAACCTTCGATAAGAAGA
+ACATGGAGCTACTGCGGTGCTCAAATTCCGAACAAAAAACGGCTGAAAAA
+CTGAGGTATACGTGGTTTTTTTTCGAAACTGATAAAAGTCAGCATAAATC
+ACGATAAACTGAACGTCCTTTGGCCAAGTTTAGAGAAACCTAGGCCACGG
+GTAGTGGTGGCCGAATTTTAAAAAAACTGGGCCACGAGGTTTACGTGGTG
+TCAAATTGCCCCATTTTGGTTTGATCTTCGAAAAATGCGGGAGACGAGAC
+GCAGACTTTTCAACTGATTTCGCATGGTTAAGAACGTGCTGATGTCATTT
+TTTTCCGTGGAAAAATTCCCGCATTTTTTGTATATCAAACCACAACGAGA
+CACTCTAACACCACCGTCCGGCCGTTCAAACGAAAATTTAGGCCACGGCC
+ACTAGGGTGAAGTGGAATGCCCTACCCTTCTCTACAAAATTCATTGGAGA
+AACCTAGGCCATGCTCAAAGAAACAGTGGCCGAGAAAGGAAAAACTAGGC
+CGCGTTCGCTTTGTACCTCTCTTATAAAACACTGTCTGTTAGTTCATAAA
+TCAGAGTCTGCCCCCTATCACTACTCTCTCATTTACCTGCCCCTCTTAAC
+AAACAATCAACCCCCCCCCCCCCTCTAAATCGACTACTTGTTCCCCGTTG
+TACCTGTCTGCGTCTAGCTATTTCTGTTAAATTTTTGGAACGAAAAAGTG
+GTATGTGAATGTACGAAACAAAAATAATAATCAATTGAATACAATTTTTG
+CCCCCCCCCCCCCCCCCCCTCCACCCCGCTTGCCTGTCTCTAACCGGTTT
+CCCCTTTTTCACCTCAATCAGCCCCCCCCCCCCCCCCCCCCCCCCAATTT
+CATTTGACTGTACATTTTCCTTTACCTATCTGCGTATCTACACAATTTTT
+GTATTTTTTCCTTTTATTTTTCTAATTATAAACCCTGCAATTTGCAAGAA
+AAAATCTCTAAAACGCTTGGCCCCTTACCCGGAGTGCGACCGTGGCCTAG
+AAATTTATATTTCTTATAAGACCCCCCGGCTCTTCCAATTTTTCATTTTT
+TTTCTTTGAAAGCCTAAATTTTCATTTTTTCTTAGAGATCAATATATTAT
+GGGTTAGTAAAAAATTTCAAAAACAAGCTCCCCGTGGGCGTGGAAGAGTT
+TTCCAAATTTCTAGGCCATACTTTTCGAAGGCGTTGGGGTACGCTCGCAC
+CCTAGTACTAAAAATTGTAAATTATAAAATTATCATAAAATTGGCTCAAA
+GCATTTGAAAATAATAAAAAAAATTTTAGAAAAAAAAACACGAAAAAAAC
+CCCTATTTTGAACATGGTTCATCGACCGGGACCTATATACTTTGAAAGCT
+TATATCTCGCTTCATGTTTGTTTTATCAAAAATTTTTCAACCAACAAAGT
+GTTTATTATTTCTTTTTCTATATTTTTGTAATTAAAAACTTTTTGATAGC
+TTCAAAAGTAACTGAGATACATGTTGTCAAACAGAGCAAACTTATAGCTT
+AGCCCAATTATTTATTTTTTGCTGTGTAACATTTCTTGTATAAACTTTTA
+AAGTTTACGGTTTTTTTAAATTTCTAAAAAAAATTATTGACACTTTAAAG
+GGAGGTCATGTGGAGATAGCCTGTACAAATAAAACTGATGAACTAGGACG
+AACCGAAATTCATAAACCATTATTTACACAGGTGATTCTTGCCTTTTTTG
+GAGGGTTAAAAAGGTTAAAAATTATTTAAAGCTTGGAATGAGCATTTGTG
+CGGCCGAGTTTTTATTTTCTAGGCCATAATTTTTAAAACAATGGCCTAGA
+AGCACAAATTTCTAAGTAATTTGAATTTCCCGCCAAAAATTTTTTTTTCC
+ATAAAATTTAAATTTCCCGTCGAAAATTTTTTTCGGAAAATTTGTATTTC
+CCGCCAAAAGATTTTTTGTCTCAAAAAATTTGAATTTCCCGCCAAAATGT
+TTTCTCAGAAAATTTAAATTTCCCGCCAAAATATTTTTTGTCTCAAAAAA
+TTTGAATTTCCCACCAAAAATTTTATCCCAAATTTTATCGAACATTTGGT
+GGCCGAATTTCCATTTTCTAGGCCACCCTCAGTTAAATCGTCAAATAAGT
+TGACCTAATTAAATTAAAAATTAACAATTTGTAATGTCTCCGACCAAAGT
+TTCATAATTGTATAGATCATCATGGTGGGAGGCGGGGTAGCACTTATGAG
+TGAACTTACCGGTTGACCGCCCGTCTATACATAGTAGCCAACACCCGACC
+ATTTTCTGCCAAATACCTATAATATCGCTTCGAGACCCAACTATTGCACA
+GTTGTGGTTTATTTCGGTTGAAGACCCAATATTAATTTACCTACAGCTGC
+TAAAGCGTTTTAAGACCTAAAAAATTAAGCAAGGCCCAAAAATCCAAACT
+TAATACTATAGTACTTCTCGTTTCGAGACCCAAAATCCAAAGCTAGGCCA
+TATTCTTGGTGAGACCCACCTGTAATAAATATCACTTGAGTGAAAGTGAA
+CTCTTACTTTTTTCTTTCGACAGCCAAAAAAAATTGAGTCAATTAGCAAA
+TAATTCACGTCTCCCCCTTTCAATGTTTACATACACATTACGAACGAGAA
+AAAAAAACGAGAGAAAAATTGAGTGAAATGGAATCAAAATGTGTTCATTT
+TTACTTTTTATGAAAATTTGGATAAGCACATGGCGTCAGAGTGTCCCATT
+TCGGCTTGATCTACGTAGATCTACAAAAAATGCGGGTGAAGAGACGCAGA
+GTTTTCAACTGATTTCGCTTTTTTTTGGGCGAAAATTTCCGCATTTCTTG
+TAGATCAAACCGCAACAGTGGATAAGCGCGCTCTATCGACAAACCCGGTG
+TGTACTACTCGCGGACAACCAGTATAGTTTTTTTTTTGAATTTTTGTTCG
+AAATTGAAATTGAAATAAGATGCCAAATTTAAATTTAAAAAATAACAATT
+TTTGAAATTAAATTTTTAAAAAAATTCCCCGTAAATCTACACTTAGTCGC
+GTAAATCGACAAGGCTATTTTTTTCAATTTTTGCCCATCGCACTTTTTTT
+GCCCAATCAATCATCGTCAATTGATCCATTGATCTTCTTCTTCTTCTCTT
+TCTCTTTTCTCACCACCGAAAATTTCATTTTATTTTTTGACACTGTCTGC
+GTCTCTCTGTACCCCCTATCTCTCGCCTCTCAAGGACTATTACAACGAAA
+AATTTGGGGAGAAGCCGTGATTTTCATTTTAATTTTGATGAAAAATTTTA
+ATGAAAATGAAAAAAAAAATTGTTTTTCAAAAAACAATCCCCTCGTAAAT
+CCACACCAAATTCAATATTCACCTTATTACAAATTGATTATTTTTCCCAA
+AAAACACACGACATCGGGCGCCCATCTATTGTTTTTTATTCCAAAAAATT
+TCTGCAACTGTCTGGGTCTCCGGTTAACACTGAGAAACAACAAATTTCAT
+TTTTCGATTCATTACATTCATTTTGAAGGTTTTTGGTTACAAATTCGACA
+CGGATTTCTGGCTTCCCTCATAAATTGAAATGGAAGAGTTTGCTGAACTA
+GGCCAACTTGGCTCGGCCATATTTGGCATAGATTTACGGCGCGTTGCGTG
+CCGCGTCGCGCCTCGATTTTAGTTGTAAAACTAAATGTGAAGTGTCCGTG
+TGGAGTACACGACTTTCCCACGCGTTGCCCGGTGAGAGATTATCAATGGA
+GCGCGAAAAATTCAATGAGGTAGGTCAGAACCCCTTGAAAATTGAGAAAA
+AAAAATCTCACAACGATACTCCGCAAAGTGTGCGTGTTGTTTATTAAATG
+ATAAATTCAAAAGCAAATAGCGATTTTGTTTCAAAAATATGCCGAAAAAA
+AAGAAAAAAAATTAAAACAAAAGTTCAGCCACCAATTTTATTTCTCGGCC
+ATGGTTGTGTCGTTGTTTATTTTTTTGCGATCGTATTTTTTCTATAATAA
+GACTTAAAATGAAAAAACATTAATAAAAATCAGTTTTCCATGGCCACTGT
+CAAAAGTCGCAACGACACTCCCCTTCCAGGCTCCTCCCCCCCGCGTGTAT
+TTTAGCATGTAGTGTAAATTACGCGATTTTGTGTATAAAACCCTAATTTT
+TTAGAAGATTTGAGAAAAAAAACTTTTAAAAAATGGGAAAAAATCCCCTT
+TCCCTTTTTTGAAATACTTTCCGACAAAGTTTAGCCAAAAGTCCAAAAAA
+AACCAATATGGCCTAGAAAAAATCAAAAACTCGGCCATCCAAAAAACTAG
+GCTACACGTTCTTTCGACCTCTGCTCCCCACACCTATGCTGCCCATATCA
+AATGTCTCCCGGACCCCTCATTCCGTCACACATTTCTCAAAAAAATGTCT
+CTTTTTCTCAAATTCTCTGTCGAAAATCCCATATCTCTTCAGTGTTCAGA
+ACTGACTGTTTTATTTCAATTCTCATGATCTCATGTCTCCCGTATGACTC
+ATTCCTTCGATATATTTTTCTTTTTTCAAAAATCATTTTTCCTATATATA
+GACTTTGTTCGGTGGGAATTTCTCATTTCAAAATATTTATTGAGGTCGCT
+TGTTCCCTTTTTATATGGTCGTGGCCTAGGTTTCTAAAACTCGGCTACCA
+TTTCCAAGTTGTAGCTTCGAGCTCTTTGTCTCGGAGTAGAAAAAATTCAC
+GAAATAAATAAAAGTTCACGTGGCCGTGGCCTAGATTTCCAAAACTCGGC
+CACCAATTTTTTTTCTCTTATCAGTAAACCACGTAGAACTCCTTTTTTTC
+TAGCCATTTTTTAACTGAATTTCCAACATATTCGGTGGCTCCATCAATTT
+TACTGATAGTAATTTCCAATAAAAAAAGGTATTTCTGTCGATAGGAACCC
+ATTTTCATCTACTTTTTGTTTCTACTTTATGGGTTTTGCCACTTTCCCGC
+ATGCCTACGTGCCTACCTATCTGCCGACCTAATATACCTCGTAGGCAGAC
+CTCGGCCGCCTTGTGGTGAGATGCCAGTCGCTTTGTAGGCAGGCGTAGTT
+TGTCTTGCTGGTATGAGTAGGCCTGTCAGCCGCCCAGTAGGCAAGCGTAG
+GCATGATGCAGGCGTAGCAGGCTTCTTAACTAGGCATCGGCTGCCTTGTA
+AGCCGGCGCAGGTAAGTGAAGGTTTCTTCGTGGCTGGCATCCTTGCAGTC
+AGGCACAAGTCGTCGGCTTGAAGGCAGGCAGATGCCGCCTAGTAGGCAGG
+CATATTTTACTTATAGGCAGGTATTAATGATCCTCTAGGCTTGCGTTGGT
+CGGTTTGTAAGCTGTCGTAGGCTGCCTTGTAGGCAAATTGAACTCTCAAA
+CCAAACAACACAAAAATTCCAATATTTTTTGTACCTTCTGATTTTGATCT
+CTGACTCATGATCTCTTTATCAATCTCATATCTTCCATTTTTAGAAATAA
+ACAATTTTTCCCTTCTATTCATTGACTTTAATCCCTTTCAATATTCATTC
+AATACACCTATAATACGAAAAACTCTTATCTTTTTTCATTTTATCACACA
+TGGTGCATAATATTATAGTTAGTGGCTATTGAAAAAGCACATCATTTTAT
+CACTTTTTGTCACTTTTCCACGATTCTCAACGTCTTTTTTTTAAACACAA
+AACGTTTCCCGTCATTTTCTACAGTACTCCCGCATTTTCATTTTCCAGGT
+GAGACCTGAGATGGAGGGCGACGAGTTGGTTCATCGTCCGACGGTCCTCT
+CGACGACGGCTTCTGCCACGTCACGGCCGCGACACAAGACTTTTGAGCTG
+TTGGGTCCGGTGAATAATATCTCGTTGGCTGATATGTATAAAGTGTGCGG
+GAAGATAATTGGCAGGTTCCCGATTGCATTTATTATTGCGACGGTGATCA
+TGTGCAGTGGTGGATGTTAGTTTTTTTTGACGTAAAAAATACAGTTTGAG
+AAAATCTTTTTTTAGATCAAAAAAGAAGAAAAATATGGAAAAAACAACAT
+TAAAATATTTTTTAGAAATCAAAAAATGTAAAAACTGTATGATTTTACTT
+AGGGCCTCCATGGTAGACAGGCACGGTTTTAGGGCCTGACGCCTGCCTGA
+AACCCACGTGGAGTCAGAAAGTCCCATTTCGCTTTGATCTTCAAAAAATG
+CGGGAGAAGAGACGCAGATATCTCATCTATTTCGCATGGTTAAGAGCGTG
+CTGACGTCACAATTTTTCTGGAAAAATAATCCCGCATTTTTCGTAGATCA
+AACCGCAATGAGACAGCCTGACACTATTAAGCCGCAAAGGCAAAAGTGTT
+TGCCGTCTGAATTTTGAAACAAAAGGTTTAACCGGTGAAAATTGAAAAAA
+AGTATAATAATAATAATAATAAAAGTAGAACTATTTTCAGTATACTAAGG
+CAAAATGATTGTTTTATAAAAAAACTTAATTTTAAAATTAGATCTCCTAA
+ATGTTTCAAGCAGCACAACTTTCATGTGATGTCAGGCTGTCTCATTACAG
+TTTGATCTACAGAAAACGCGGGAATTTTTCTCCCAGGAAAATGTGACGTC
+AGCACACAATGCATAATCAGATGAGATTTCAGCGCCTCAACTCCCGCATT
+TTTTGTAGATCAAACTAAAACAAGACTCTCTGACACCACGTGAATTTTCC
+AACCATCAAACTATCACAAAAAAATTGGCGCCAAAAAAACTTCTTTAAAA
+ACTTCTCATTTCCAGTAGGAACAATCGGTCTCGAACTGAAGGATAATGTG
+CGCGACGGGTACACGCCGAAAAACTCGCTATCCCGACTGGAAAATCGCCT
+TTATCGAGAGTTCCTGAGTTCCGAAGGTGATCCGGTGATGACTACAGTTC
+TCATGACTGCCAAAGACGGAGGATCCATGCATCGGATCAAGTATTTGGAA
+GAAGCACAGAGGGTGAGTGGCATAACATATCGGATACCGTATTTCCTCTA
+TTAGTAAGGCATGCAAAACTGATTTTCGGACACCTAATTTGATGCAAAAC
+TAATAGAGGGTGCAAAACTAATTTTCGAACAGGTTTTTTCTCATTAAGTT
+ATATTATAATATCATCAATTTCAATAACAACTTCTGAACCAAAATGGGCG
+AATTTTACGACTGATACGCAAAAATTGTCCGAGTTGTACTCATATTTTGC
+CAGTTTTGACTTGTTATACCAAGTCTGTAAGAGTTTTCCTAATTTTCAGA
+ACGATTTTATAATGCAAATTTTGAATTCCTAAACATAGGGAACAAATTAA
+GGGGTGCAAAACTATTAGAGGTGCAAAACTAATAGAGAGTGGAAAACTAA
+TTTTCGATTAGTGATTTTTGATGCAAAACTAATGGAGGTGCAAAACTAAT
+AGAGGTGCCTAACTAATAGAGGAAATACGGTATATTTTTTTGAATAAAAA
+ATTTCAGCAATGGCTCTACATCTCCAAAAACCTATCCGCAGACGTTGGAA
+ACGGCGAGTTCATGAAATTCGGAGATTTCTGTGGCCACTACTGCCAAGCC
+AACGACATCATAGGATACTTCCTGGACGCCTACAAAACCAAGTCAGCTGA
+CCCAAAAATGGATGGCTACCAACTCAATTACCCAATTACCACAGTAATGG
+GTTATCAGCTTCATCTCGAGCGTAACTTTTTCGGGGTTACTGTGAATCAG
+TCGGATCCGGTCACTAATATTCAGAGTATGAAGGTTCTGACGCTTCCTGT
+GTTGTCAGAGGTACGGACGTTTGAGGATACGGATAAGCTGAACAAGTGGG
+AGCTGGCGGTTTATAACTATGCTACAGGATACTCTGCACTCGAGGGTGAC
+GATCATTTGGTGGAGATTAATGTGAGTGAATAAATTGGACCATTTCAAAA
+ATATTGGGCCAGCCCTAAAAAGACAGCGGGCCGGCCCATATCGACCCACT
+TAACAGGCTCAAAAAAGTTTAGTTCAGTTGTGTGCCGCAAATTTTGAAAT
+TTGCCGAGCTCGGCAAAATCGGCAAATTTGGTAAATCGCATAATTTTCGA
+GCTCGGCAAATTCGACAAGGCTAAATGTTTGAATTTTGCCGTTTTCGGCA
+AACGGCAAATTTGGCAAATTTGCCTTACACCCCTGGTTTAGGGGTTTCGT
+GTTTAATTTTCAAAGCTTAGATAAACCTCTTTTCCAGGTGATCGGTGCTG
+AAGTCGTCGACACCGAAATGAACAAGGACGCTCAGAAAATGGTGCCCTAC
+TTCATCGTCGGAATCGTCTCGATGATCATCTTTATCTTCTGCACCGTATC
+CATCTCTGCCTCCTACTACGGATACTTCTCCTGGCGAATCGGACTCATCG
+CCCTCGCCTGCCTCTTGGTTCCGATTCTCGCAATTCTCACTGCATTCGGA
+ATCAATAATATGCTGGGAAATCGAACGAACTCTCCGATGATGATCATGCC
+GTTCTTGATCAATGGAATCGGAGTCAACGATGCGTTTTTGACACTTCAGA
+ATTGGTTGCAGCATAGCCCGGATCTTCCGTCAGGGAAGCGGTTGGGGTAT
+ATGTTGGCTGAAGCTGGTCCATCGATCACTACGACCACTTTGACAAATGT
+CATTGTTTTTTTGATCGGGTGGATGAACCCAACGGAAGGTAAGGTTCAGT
+GGTGGACGGCAAACTACTTTTTCCGGCAAATCGGTAAATCGGTAAATTGC
+CGGAATTGAAATTTCTGGCAAATCGGAAAACCGGCAATTTGTCGATTTGC
+CGAATTTGCCGGAAAAAAAATTGCCGAACGGCAACTGCGCCCTGGTAAGG
+TGCATAGCTTTGGCCTCTAACATAAAAAAATTTGTCTATTCATCCTTTAT
+TCCAAAACGACATGTATTCCAGAGATGTCAATCTTCTGCCTTGGATGTGC
+AATCTCCCTACTCCTCGCCTACGTCTACACCCTCACGTTCTTCTGTCCGG
+TGCTAGTTCTTCTGCTTAGCGAACGCGTCAATGAGCCCAGCAAGCTCGAG
+GGCACTTTCAACAAGGTTCTCGGATTCTACGCAAAAATCATATGCAGCCG
+ATGGACATTTGCACTTCTCATCATCGGAAGTCTTGTCTACTGGGGTTTCG
+GTATCTATGGAACACTGGGGATCCGTGCCGTGTTGAACACTGCAAAGATC
+CTTCCCCTGGAGACGCCGATCCGCAAACCGAACAGGATTATCGAGGAGAC
+CGTGTGGAAAGAGTTCTACCCAGTCACCGTGATTGTGAACAGCCCAGTTG
+ATATAAGCAATGCAAATGCACTTCGAGCATTTGACAACCTCGTTCACGAC
+TTTGAATCGATGGAAAAGTGCCGGGGATCCGAGTACACCATATCTCCAAT
+CAGAGACTATCAGACCTATTTTTACGGTGTAGGAGCCGAGGACTTTGATT
+ATGAGGAAGAAACCGTGAAGAACACCTCACATTCTTTAGATTTCAGTGTA
+AGTTAGCAGTCCACGCGTTCCTATTAAAATCTACATATATGCCTATAACG
+TGTTTATCCACAGAAGAGAAAAATCGCCATATCTGCCGCGCAAATGAATC
+CGCGGGAAGAGACAAAACTACTGTAGTTTTTAACCAATTTGTGTAGATTT
+ACGAGCTATTGCGTCATCGTTGTATTTAATTTTGAGCCGCAATTTTTAAT
+TTTCAGGCGTTTCACACGTTTTTATATTGAAATTTATCTATTTATTGAAT
+AAATCTTAAAAGAAAACACAAAAAAATTAGAAAAATTCCGAAAAACGCCT
+GAAAATTAAAAATTGCGGCTCAAAATTAAATTCAACGATGACGCAACAGC
+TCGTAAATCTACACAAATTGGTTAAAAACTACAGTAGTTTTGTCTCTTCC
+CGCGGTTTCATTTGCGCGGCAGATATGGCGATTTTTCTCATCTCTGGATA
+AACACGTAATACCTACATATTTTGTGTGCCTAAAAACATGCCTAGCAGTG
+AAAGTAGACAAATGTAAGCACACAAACGTGAGTAGGGCTTAAATGGTATG
+CAGGCACTGTTTTAGGGCCTGACGCCTGTCCAGGCCTGTCTTGTACGTTT
+CATCAATTCAAGCCGTATATTTCCAGAAGCTCACCGGATTCCTTGCCAAC
+CCTATCTACAAGCATCACAAGGGAGGACTAAAACTTAACTTTTCAAATCC
+GTTAGTTCCTATCTGCCACCTTACCCTAAATCGAGTACCATTTTCAGTGT
+TCCAATCCGAAAAGTGCAACTGATATTCGCTTATGAAAACGTAACCTCGT
+GGGATGAACGGATTCAGATTATGCAGGACTGGCGGACCATCGCAAGTTCC
+CACGTGGCCCTAAATGTTTCAGTGTGGAATGTGAACGCAATGTTCGTAGA
+TCAAATGCTGAGCCTGAAGGGATTGGCGATCTCGGTAAGATCTCAATGGT
+TCCAGCGCCCTATAAATACCGCTTATTCTTTCAGAATGCCCTAGTCACCT
+TGGGATGTATGGCTGCCGTCTGTGTAGTCTTCATCCGCAACCCCCTCTCA
+GTTGGCCTAGCGACCGCTTCGATTTTATCCATCTCCATTGGAGTAACTGG
+ATACCTGTGCTTCTGGGACTTGGATCTGGACCCTGTGACCCTGTGCGCAG
+TAATTGTTTCAATTGGAATGTCCGTTGACTTTGTTGCCCATGTGGCCTGT
+CACTATCAGGTCAGGTATAAAGAGTTCGAGGAGAAAGGAGTATTGAAGAG
+GATTGAGATGAAAACTCCCGAATCTCGAGTCGTCAACTCGCTGTCCAATG
+TGCTCTGGCCAATGGTCCAGTCGGCTTCTTCAACTCTTCTATGTGTACTT
+CCACTTGGTATTCTACAGGTACCTACCAATACCTATACTTTACCGATAAC
+CCTACCCCTCAAACATTCCAGAACTACCTCCCAATGGTTTTCGTGAAAAC
+CATCCTGCTCGTCGTGATCTGGGGAATGTTCCACGGTCTTGTGCTGCTCC
+CGTGCATTCTTGCACAGTTTCCCCTGTCTGTGTTCAACAAGACGTTCGCC
+GACTTGTTGTTCGGCAGAACATCCTCTTCGTCTTGCTCTTCGGAGTCCGA
+TTCGGAAACCGACACCGGTGATGCTCAGGAGATGGTTCCGCTCGCTGGAA
+CCGAGAAGGCTTAAGATCTGAAATTAGTTGTTGTTTGTTATTATGTACAG
+TTGGGATACAAAGTGTATTATGTAGTCTGTAGTGTCGCAGTGCTACAAAC
+TACAAATTCAAAGCTACAAACTATAAACTCATTGAGATCTGGCAGAGCTT
+TATAGTTTGTAGTTTTATGTAGCAGCTACAAACTACAAATTTCGATTGTT
+GTAGTTTGTAGTATGGCGCACAAACTACAATGTACATTTTGCAAGTTTTC
+TAGATTTTTTTCTCACTCACACACACACACACACACCGTTTTGCTACGTG
+GCTGCGAAAATGGAAAACTCGGCCACGTCGCAATTCACACATCGCCAGAA
+ACTTCTAGCTTTACCAGTAGCTTTTCATGATCTACTCTTCTTTTTTTTCC
+CCCCTCAATTTCTATTTGAAATTTCAGAATTCCCTCAATTAGTCTTCTGT
+CACCGTGTCCTCCTCTTTTCCGCAAGCGGGTCCCCTTTTCCCCCCACAGA
+TCGGCTTCTCAGGGTTCCTATAGCACTTTTTTCTTCGATTCTTGTCACAC
+AAAAAATTGTACTTCCATCGCTCGACGTGTCCATTTTTTCTTGTATTTTT
+TAAATGCATTTTTTGATAAATTTGATTTTTTTTATCATCCAGAAAATGGT
+CAAAAATTCAGATTTTCTTGCTGGGATTTTGCTGGAATTTTTTCAAGCAT
+CAGACATGCAAAAACTTATGCAAAACTACACAACACTATCGATGGGGACT
+GTTCGACTCTTCACCCCAGTCAAACTTTTTTTCACTATTTTTTTTAACTT
+CTGTTTTTTTGGTACTTTTCTGGCCGTTTTTATGGAATTTTTTAACCCGA
+CATTGGAGTTTACCTTTTTTTGTTCAGGATTTTAGGAATTTCTGCGACCT
+TCTCACTCATGTCCTCCAGCCCCGCCTAAGCCTATGCCTTAACTCAAGCC
+TAAGCCTAAGCCTAAGCCTAACCTAAATCGCGTCAGAGATAACGTTCGCC
+ACTGACGCCAAGCCTCAACCTAAGCCTAAGCCTAAGCCTAACACTAAGCC
+TAAGTATAAGCCTAAATCTAGGCCTCAGCCTAATACTAAGCCTAAGCCTA
+AGCCTAAACCCAAGCCATAAGAAGACACTCTAAAAATGTTCAGATTATTA
+AAAAATTACATTCAAAGTTTTCTTCAAAATTTTGCTTTCGACTTTCCAAG
+TAATCAATACCATGTAGAATTCCAAAATCTTCATACAAATCCCTCCCCTC
+TTCACATCTTTCCCGACAGCTTGTACTATTTCTCCTCCACCCACTAGGCC
+AGGTCAACGCTGCGTCTCTCGTGTTTCATATGCTATCTCCCTTTTGTGGA
+ATCCGTTCATCGTTTCGGATCGCTTACTTCTTCCGCGCGCGTCGCATTTC
+ACTTTGAAATAAACTTCAGTTTTCCTTTCCAAAATTTAATTGGTGGAAGC
+GTTTGAACATGCGAAATTTGTTAATTATCGTGTGTATTCATTTAATATTA
+CTACTTGTACATTTTACCGATGCATGTAAGTTTTGGATGTATCAAAAAAT
+TAAATAAATTTCTTAAAGGTGGAGTAGCGCTAGTGGGGAAATTGCTTTAA
+AACATGCCTATAGTACCACAATGACCGAATATCATGATAAAAAAATTCAA
+AAAATTTTTTAAAATTTTATATGATTTTTTGAAAATTGGAAAAATCTCAG
+TTTTTGCCTAATTCCAATTTGAATTACCGCTAATTGGATTTGTTCGATGG
+AGCGCGCTTGCACGTTTTTAAATTTATTTATTTTATTTTTTGTTATTTTC
+CACCGATTTTTAATGTTTTCGGTGTATTTTTGCTCTAATTTTAGAGAAAA
+AGTCAAGATGAATGCAGATTTTCGATTAAAAAGCACGCTCACAGGCGTAA
+AAATGACAAAGTAACGATTTTAAACGGTTTCGAACCTGAATTAATTAATT
+TCACTGATTTACGACTGTAAGCGTGCTTTTTAATCGAAAATTTGCATTCA
+TCTTGACTTTTTCTCTAAAATTCGAGCAAAAATACACCGAAAACATTAAA
+AATTGGTGGAAAATAACAAAAAATAAAATAAATAAATTTAAAAACGTGCA
+AGCGCGCTCCATCGAACAAATCCAATTAGCGGTAATTCAAATTGGAATTA
+GGCAAAAACTGAGATTTTTCCATTTTTCAAAAAATCATATAAAATTTAGA
+ATTTTTTAAAGAATTTTTTTATCATGATATTCGGTCATTGTGGTACTATA
+GGCATGTTTTAAAGCAATTTCCCCACTGGCGCTACTCCTCCTTTAAAGTT
+TGAAGTTTTAGTAAAAAAAGAGTGTCGGTTTTTTAGTTAATAATATTAAT
+TTCCAGTCGCCGGAACAGTTCGACCATTTTTCACCACTCTTCCAGTACCT
+GGAAGAAATGTTCCTATTATGAGATTATTCGAGAACTATGCTGCATCGTG
+CCGACCAAAAAGTAAAAAGGACTTCAATGTTGATCAGCTGGCAAATGTAG
+GTTTTTTCCCGCAAAAAGTCGTATTTCGTGCAAAACCGGCAAAAGCAAAA
+ATTTTGAATACCGGCAATTGTCGGAGTTGCCGATTGCCGGAAATCAAAAT
+TGCGGGAAATAAAATTTTGATACTTTTTTGTAGATTTAGGAGCCTAAAAA
+TGCATTTTAATGAACAATTTTTAATTTTCAAGCTCAAAATGATTTAATCC
+TTTAAGGATTGACCGTTTTCTTTAAAAAAGACTAACCGAATACTATAAAA
+AAAGGTGAAATTTTTTCAATTTCCAAAATATAATTAATTTTGGCAACTGC
+CGATTGCCGGAAATTGCCGATTGCCGGAACTTCACAATACCGGCAATTGC
+CGAAATTGCCGATTGCCGGAAATTTCCAAAACCGGTAATTGCCGGAATTG
+CCGATCGCCGGAAATTCCCGATTGCCGCGCACCCTTGTATTAAAGGATAC
+GGCAAACGATTTTTTCCGGCAAGCGGCAATATCGGCAATTGCCGAAATAA
+AATATTTTCGGCAAACGGCAAACGGCAGTCAGCAACATGCCACTTCTCCA
+ATTTTCGGCAATTTCGGCAAACGGTCAATTTGCCAGAAATCATCGGAAAA
+TTGTGATCTTGCACATTTTTTCTGGAAATTTCAGAATTTCAATTTTAAAC
+AACAACATTGTACACATCCTATGAATGACACATATCTTAAAAAGCCAGTA
+AATTCTATAAAAAATATCTAGAGAAACTGGCAAAATAATTAAAAAAGGCA
+CGGATTCATGTGATTTTGATTATTGAAAATATCTTTGAAAACTTTCGGAA
+AATTGATATCCGGCAAATCGGCAAATCGGCAACTTGCCGATTTCCCGAAT
+TTGCCGAGCAATGAACTACACTGTTCCAAATCGAATTCGTAACCGATATT
+ATACTTAGGAATGATATTTGTAACTCGTATAAATATTAAATAATATATAT
+ATATTCCAGCTTCTCCAATCTCTCCAAATGGATGAAGTAGCCACAAAAGC
+CTACAACTCCCTATTCTTCTCAATGGCTGATATGCAAATCGAAAAGTTCA
+TGGGTAAATGGTACACAGTTGTTGATTCGAAAGAAGTTCATAAAGAGGAT
+TGTTCAATTTTCTATTGTAAGTTTATTTTCATTCTGAAAATGAGATGCAA
+ATTTTCAGTCGATATGGTACTTCAAACTCCATACACCGCAACATTCACCT
+CAAAGCAGTACGGAGTGATTAATAATGATGTCGTCACCAATGAGGGGTAC
+GGTAGTATGGTTGGTCCAGAGCCCGGAGCCGTTCTTATTACAACTGGTAG
+TGAAAGGGATCAGTGTCCATGTAAGTATTTTAAATAACTTTGGTCCGGTG
+ATATTAAGATACAAGTTTAAATACTTCCCGTTTCAAAAACTTCGAATTTC
+CCGCCAAAACTTTTCTCTGAAAATTTTAATTTCTTTCCAAATTTTTTTCT
+TTGAAAATTTGAACTTCCCGCCAAAATTTTGTAGTCAAAAAATTTGAATT
+TCTCTCCAAGAATGTTTTCTCAGAAAATTTGAATTTCCCGCCAAATTGTT
+AATGTCAGAAATTTTGAATTTCTCGCCAAAATTTATTTTCTGAAAATTTG
+GATTTCCCGCCAAAATTTTTTTCTCAATAAATTTAAATTTCCCGCCAAAA
+TTTTTCTCTGAAAATTTTAATTTCTTTCCAAATTTTTTTCTTTGAAAATT
+TGAATTTCCCGCTAAAATTTTATTGTCAAAAAATTTGAATTTCTCTCCAA
+GACTGTTTTCTCAGAAAATTTGAATTTCCCGCCAAATTGTTAATGTCAGA
+AAATTTTAATTTCTCGCCAAAATTTATTTTCTGAAAATTTGGATTTCCCG
+CCAAAATTTTTTTCTCAATAAATTTAAATTTCCCGCCAAAATTTTGTTAT
+CAAAAAATTTGGATTTCTCGCCAAAATTTTATTGTCAGAAAACTTGAATT
+TCTCGCCAAAGTTTTTTCTCAAAAAATTTGAATTTCCTGTCAAAACTTTG
+TAATCAAAAAATTTGAATTTCCCGCCAATTTTTTTTCTCCGAAAATTTAA
+ATTTCCCGCCAAAACTTTGTTATCAAAAATTTGAATTTCTCGCCGAAATT
+TTATTGTCAGAAAATTTGAATTTCCCGAAATCTCTATGAATAAAACATTT
+GCAGTTTTCCCTGTACGAATCGGTGGCTTGAGTGACGAAGGAGAATATCA
+ATACATGATCTTAAGTACACCACTGAAGTATCCAACGATGGTCTTGACAA
+GGTAAGTTTGCCTTAAAATTTGTTTTCTAATTATTCCAATCTAATATTCA
+TGTGATGTTGAAAAATGCAAACATGTATTTTAATACATTTTCCCCCTATT
+GATGCGTACCGAAAAATGTAGAAAAATGGAATCATTTTTTTGCATTTTTC
+GACATTTTCGACATTTTTGACATTTTCCGACATTTTTCGACGTTATTCGA
+CATTTTCACGCATTTTTCAGAGTTTGCCGAACTAGGCCATTTTGGCTCGG
+CCATATCTGGGGTAGATTTACGGCGCGTTGCGTGTCGCGTCGCGGCTTGA
+TTTTAGTTGTAAAACTAAATGTATTTGTCCGTGTGGAGTACACGACTTTC
+CCAGGCAATTGTCAATGGAGCGCGAAAAATTCAATGAGGAAGGACAGAAC
+CCCGTGTCCACAGGAAGAATTTTCTCTGCGTCTCTTGTCTTTAGCATTTA
+AAGTGGGGCGACGCCGATGTAGAAAAATGCTGAAAAATTTCGAAAAATGT
+CGAAAAATGCACAAAATGATGGCATTTTTCTACATTTTTCTGCATTTTTC
+GGCACGCAAAAAACATCACATGAATAACCCCATAAAAACTCCAATTTTTC
+CAGAGACCTAACCCTATTCGAAACGAAATGGAAGCGAGAAGTGTATGATT
+TTGTTGAGAAGAATGGTTTCATGAGTCCAATGGCAGCATTGAACACTCGT
+CTCCATTTCACAGATGTCGATGTTTGCAGAAAAGTGAATAAGTTATATGA
+GAATGGAAATGTTTGAGTTGAAGATTATCTTTTTTCTGATGATACGGCAG
+AGTTTTTGACGGGTTGTGCAGTGTTTATTTTTAACCTTCATGTGTATTTA
+AAAATAAAGATTAATTTAATTGAATCTGTGTTTAATATGAACTTTTAAAA
+CACAAAATTTCAGATTTTGGTTTAAAAACTGTAGACACTTGATACTTTGT
+TGAGTGTACCTAATTTGAATTTCGCGAAAAAATGACTGTCATATGATTCT
+TGACCGTGTACACCTCTCGGGCAATACATTAATATTTTAATATTATGGAT
+TATAAGCATTTTCAGTAGACTTTCCATATTTTCTCATGATTATTACTCAT
+TTTTATGACGAAAAGCATTGTTTGGAACTCAAAATTATCAACTTTAAATG
+TTAAAAAATATTCAGGAAAACATAATATTTGCCTATTAAAAAATTTCCCA
+TTAATTTTCCACAAAAAAGTTTCTTTTTTCTTTTTTTAATTTTTTCTCAG
+AAAAATCAAATCTCCCAACAAAGTTTTTCTCAGAAATTTTGAATCCACCG
+CCAAAAATTTTTCTCAAAAAATTTGAATTTCCCACCAAAAAAATTTTTCT
+CACAACTTGAAAATTTGAATTTCCCACCAAAAATGTTGTCTCAAAAATAG
+TAAGTTTCCCGCCAAAACTTTTTTTAAAAGAAAATTTGAATTTACCGCCA
+AAAATTACTTACCAGAAAATTTCAATTTCCCGCCAAAAATGTTTTCTCAG
+AAATTTTTAATTTTTGGTCAAAATTAAAATACTACTACGGTACCTTAATC
+CTACACCTCCACCCAAAAAATCATTTTTCAAAAACTACTACAGTACTACT
+CCTACAGTACTCCTACCGTACTCCTAAAGTACTCCTACCGTACTCCTACA
+GTACTCCGACCGTACTCCTACAGTATCACTACAGTACTCAAACCATATCC
+ACCACTAACACCAATCCAATATCCCTTCAAACGACAATAACTTTTTTATT
+CAAAAATACAGTAATCTTACTGTAGACAATCTTTTAAATTATAGTCTTCA
+TCCAAAACTATAACGGACTCCATCCCATAAAAAGTAAACGACAAGTCATA
+AAAATTGGAATTCGCGTAGTTTGCTCTTCCGTGAAGGCAAACACACGTGC
+TCAGCTATATTGATAAGAGATGAAAAACGAGAGGAATCAGTCGAGGTGTC
+TGATCTACTTCCAGGATGGTGACCGCTCTTCTACTCCTATTGGCTCTTGC
+AGCCACCTCTTTGGCGGCTCTTCCAGATTTGGGATATCCCGGATGGCAGT
+GCGATGCATCGCTTTATCAGAAGTAGGTGGCTTACTTTAATTACTAAAGT
+TTGAAATTTTCCTCGCTTTCAGGAGCAAAAATACCCCGACTTCTGCCCAC
+TCCGTCCGATTCACCGACATAAAAGTTTTGGGAGCTCTCGGAGACTCCTT
+GACCGCCGCCAATGGAGCCGGAGCACCAAAGGGAGACCCTCTGGCTGTGA
+TCCTTCAGTACAGAGGACTAGCCTTCCAGTGTGGAGGTGACCACTCTCTC
+GACGAGCATGTCACTGTTGCAAGTAAGCCATTTTTCTGGGGAATTGAGAA
+AACTGAGTTGTTGTAGATGTGCTGAAAAAGTTCAGCCCTAACCTAATGGG
+ATACTCCACTGGAATCGGAAGTGCCAACGTTTGGGAGGTCTCAAAACTGA
+ACCAAGCAGTTCCAGGAGCTGAAGCAATCGATATCATCACTCAGGCCAGA
+GCTCTGGTGCAAATTATCCAAAGCCACAAGGAGGTAGCCAAGTCCAAACT
+AAACATCAATTCCGATGCATTTCCAGATTGATTACAAAACTGATTGGAAG
+CTTATCAACGTATTCATTGGAGCAAACGACATGTGCGCCTATTGCAACGA
+CCGAGAAAATGTAAGATAGTCAAAGATCATTCCACACCCGTTTTATTGCA
+TTTTTATAGGGCCCACACTCAAAAGCAATCTGGAAGCAAAATGTGATCAC
+TGCCATTCAAATTTTAAAGGATAACTTACCAAGGTAGGTAAACTATAGGG
+ACATGACATTCTAAAGTAAATAACTATAATATTATGAAATTGTCACATAC
+CTATACCTACCTATAAATACCTACATGGTCCAGAGCTGTGTGGCAAATTT
+TGAAACCAGCAAATTCGGCAAATTTTCCGGGGTCGTCATACTTGGTAAAT
+CGCAACATTTTTTGGAGCTCAAAAAGTGCCAAAATTAACAGAAAATCTAA
+GTTGTTAAACATTTGTGGCAAATTCCAAATTTGTCCAAATTTTTGAAATT
+TGCCTTGCTCGGGCAAATTCGGCAAATTTGCCGTGGTTGTCGGACTCGGT
+AAAGCGCATCATTTTTTGGTGCTCAAAAAGTACCGAGTTGATGGAAAAAC
+TAAGTTGTTAAACATTTGTGGCAAATTACAAATTATGTCCAAATTTTTGA
+AATTTGCCTTGCTCGGAAACCGGCAAATTCGGGAAATTTGGCACACCCTT
+GATCCCATAGCAGTGGCGCAAAAAAATCTTTAAAATTGTGGCCGTTTCCG
+TGCCAATTATAAATTAAAGTTAAACATATTATCGAAAAAATACGATCGCA
+AATTTTTCTCGTAACTTATTTTTGATCTACCTTGTTGACTAGGCTCCTCC
+CCTTCCTTCGACAAGACAGCCACAACAAAATAACAACGGCAACAAGATTA
+TGGGCAAACACGTGGTGCCAGGCTGTCCCATTACAGTTTGATCTACAATA
+AATGCGGGAATTTTTCGCCCAAAAAAAAAGTGACGTCGGCACGTTCTTAA
+CCATACAAAATCAGTTGAGAACTCTGCGTCTCTTCTCCCGCATTTTTTGT
+AGATCAACGTAATTCAAGCCAAAATGAGACACTCTGACACCACGTGGGCA
+GAGTCAACTTCCAAAGGTAGATCAAAAATTAATTATGAAAAAAATTTGCG
+ATCGTATTTTTCGATAATAAGAGCCAACATTTTTCGGCTTTTTATGGAAA
+TTTTTTTTTCAAAAAGAGGAGTATGGTCCATAACTATGCCATCAATACCA
+AGTCCTTCCAGAACCATCGTATCCATGACCGGAATGTTCGACATGGCCAT
+GCTTCGCCAAATCGACCACGACAAGTATTTCTGCGACGGCCTCCATGTGT
+TCGAGTGCCCATGCGAGAAGAACAAGGACTTCCCGAATACCGACATCTCG
+GCTGCCTGCCATCTTTACATGGATGCTCAGCAGGAGATTCAAGACTCGGG
+AATCTTCGACTCAACAGATGACTTTACATTTGTCGTTCAACCATTCTTCA
+ATGGAATCACAGTTCCACCACTCAAGCCCGACGGAGAAGTCAATCTGGAT
+TGGTTTGCACCGGATTGCTTCCATTTCTCAAAACTAGGCCACGCCAATGT
+TGCCAAGCACTTGTGGAACAATATCGTTCAACCAGTCGGATCCAAGAACC
+ATCAAGTCAATCTGTCAGATCCTACCATTCCACTAAACTGCCCAGACACC
+AAGTGCCCATTCTTCAGAACAACTAAGAACAGTGTTGACTGCTCGAAATA
+TATGACTGCCTAGACTGTAGGAAATTGTGTTTGTGTGTGTAATTTGACGT
+ACTTATCGGGTCTGCAATAAAATGTTTTATCGTGTAATCTTTAATTTTTA
+ACGTGTGAGACATAAAAGAAAGAGCACCCTCAATAAAAATATCCACGTGG
+AGTACACAATATAGCTATCAATAGAGCGAGTAAATATTTTTGCAATAATT
+ATTTATTAGAAGAATGGAGATCAAGGTAAAGGAAGAGATCTTGATTTTGA
+AAAAAAGATACTGGAAATACTAATTGTTCACGGGATTTCATAGAAGGGGA
+TATATCACGACTTTTTCTTTGAAAAATAAAAACAACATAAAATTATTGCG
+GCTTCACAATCTGATCATCCGGTATTTCTCCAGATCTTTCCTTTTCCGAT
+TCGATCTTCTTCCACTTGGTACGCCGGTTTTGGAACCAGATTTTCACCTG
+GAATTTGAGAAATTTCAGCTATGCGTTGAGTGCCGCGTTACGTGCTGCGT
+TGCGTGCTGCGTTGCGTGCCGCGTTGCGTGCCGCGTTGCGTGCTGCGTTG
+CGGGCTGCGTTGCGTGCCGCGTTGCGTGCCGCGCTGCGTGCCTACCTGCG
+TCTCCGTGACATCCAATCGTTTTGCAAGCTCACTTCTGTCACTACTTGAC
+AAATACTTTTTCGCCTCAAACTGCTTCTCCAGTTCGAATACTTGTTTCCC
+GGAAAATGTCGTCCGCGCCTTCTTTCTCTTTGTTTTTTGACATTTTTCTA
+TAGGAGACTCTTTGGCTTGGTCGAGGCTGGATTCTGAAAAAATATTCTTA
+ACGGCTGATTATTTTTCTACGTGTAGCATTTTTCCGAAATTCATTGAACA
+AAATTAGTAAATTTCCAAAAAATTTTTTTTCCAAAATTTCGAAAACATTT
+TAATTTTTTTCAGATTTTCTAATATTTTAAAACAAAAATTGAGAGTAAAG
+GAAATAAAAATTGTGTCTTGTAATTTTTGTAATTTTTACTCAAAAAAAGG
+CCAGTGAAATACTATTACAGAAAATACGAATCGATGCACCATGTCAAAAA
+GAATAGTATTTCACCTCAAATGCACCATGCCCAAAACTAGTCTATTTTTC
+AACTACAAAACTTCATACACCTAATCCAAAGAAATCAACTTACTGCATCT
+TCCAAATTCATCAATTTCTCCATTAACAGTTGGTAAGTCAAGTATATCCT
+TTATCAGGTGACTAGTTCTTCTCTGAGGCTTCACATCAGACGTCAACAGT
+GCAAAATAGGGTTGAAGTAGTTGGAAGAGCAAGTCAGTTTCCATTTTGCA
+CGAATGAAAAGAACTTCTGAGAGACTTCTCTATACAGTAGGTCTCGAGGT
+CCCCGCCTTCTCTTCAATCAAATAATTGAAATTCTGGACTCTCGGGGGAC
+TTTTGACGGTTGACGACGACGACAATTTGCCAAAGTGGTCGACAATGATT
+GCGCAATTGGTGTGGAAAGAAGAAGAAGATGGGTGAGTTCTGAGATGATG
+ACAAAAAGAGCATGAGCCAGCAAATTGAATAAGAGACCGGATTTCGAGAA
+GGAGGAGGGGGAGAGGAGGATTGGTGGTAAGGGATGATACTTGATGCAAT
+TGAGGGAATGAGTTTCTCATACTTGACTATTAAATACTTTTCTTGAACTT
+AAATATTTGAATTGAAATTTTGGAGTAGCGGAGGCACATGTGATATTATT
+GTGCTAATTTGTAATACTTGGACTTTCAAATATAACCTCAATTATTTGAA
+AAAAACCTTTTGAATAGACCAGCAAGGTTGATCTACAATTTTTCATGGAA
+ATCGAATTAATTTTGTAAGGATGTCTACTGAGTATAAGCTTATTGTTAGG
+CTTAGGCTTAGGTCTAGACTTAAGGCTACACTTAAATTTAGGCCTAGGCT
+TAGGCTTAGGCTTAGGCTTAGGCTGAGGCTTAGGCTGAGGCTTAGGCTTA
+TGCTCAGACTTAGGCTTAGGCTTACGCTTAGGCTTAGGCTTAGGCTTAGG
+TGTTGGCTTCAGAATAAGCTCAGGCGGGGGTGAGGGAAGGGTAGAAAAAA
+AAGAAAGAGAAATTTCCAGAAATTCACAAAATCCAGAAAAAAACATATCT
+TTCACAAGTTTATATTTTTATAGCCTAAAAAATTACTTTTAAAATGAGGA
+TATGCAACCCGCACGCAAAAAAACCTTTTTTTTTTTGAGCAATTTCACGG
+CTCTTTTTTTTTTAATTTAAAAATACAATAAAAAAACCAAAAAAATTTTC
+CGAGCCCAAATTGCTCCCAAATGCTCTAAATTTCTTTTGAAGTTTGATAT
+ATTCCTATTAGAACTTGAGGAAAATGTAAAACTAGAGAAACATAATACTA
+CGCATGTTAAATGTAAATTACTTACTTTTAAAAAGTCGTACGTTATTTTG
+GAAAGTTTGAGGTTTTTGCATTTTTTCCGTAATATCACTGAACACTTTTA
+TTTAAATATCATCAATTATCGGAAGTTTATAGGTTGCAGGAGAAAAAATA
+TATTCTAGCGGGAAAATGAAATGAGACGGGGGGACATTTTTAACCAAAAA
+AAAATCAGAAAACAGTTGGTAATAAAATTATTCCAAGAAAGTATAAATTC
+ATGACTTCCATCTTGGGAACATTCTTAAAAAATGTCAACGAATAAATCTT
+TGTGGCAAACAAACTTTTTCCATAAATGTTTCAGACCTTATATAGCGGAC
+ATGAAAGTTGATTGCTTATTTGATATGTCTTGAGTTTATTTTTTTTTATT
+TCAAGCGAGGGGAGATTTATTTGCCTAGATATATATATAATTATTACTGG
+AACGAACTGGAAAAAAACTTGGGATCAAAAAAATCAAAAATTCAAATTCA
+AAAATTCAATTTTTCGAAACTTTTTCTACAGCTTTGTCGAGAAGCAACAG
+ACAAATACTTATAGCTAAAATTTTATTAATATTCTAGTTTTAGTCATGGT
+GAATCGAGAATTTGTCAATTTCCATGTGGTATCTTAAAAATAAACCGATA
+CACGTGGTGTCAGGCTGTCTCATTGCGGTTTGATCTACGAAAAATGCGGG
+AATATTTTTCCAGAAAAATTGTGACGTCAGCACGCAAAAATTAATAAGGG
+TCTAACCAAAAAAACTTGAATCTTGGAAATATTTTTAATTCACCCTAAAT
+TTTCCCCTGATTCCGAATATCTATGTGAAAAAATTCAAAAAAAATTTCCT
+GAATTTATATTTAAGCTTGAAATCTTTCATAAAAATTTTTTTTTTTTAAA
+TTTCATTTGTACTCGCATCACTTTTTTCAAACTCGCGCCCAAATAAATTA
+GCGCGCGCGTGCATCGTTTGACTTTTTTTCGTTTAGTTTTTTTTATTTTA
+GCCGAATTCAATTTTTTTAAAACCAGTTTCATTCATTTTTGTCGGTTTTT
+TTTTTCTGAAAAAAATGTAAAAAAACGAAAAAAAATCAAACAATGCAAGC
+GCGCTCCAATGCTAATTTATTTGAGCGCGTATTTAAAAAAGAGACCGGGA
+TACAAATGAAATTCGGCGATTTCAAGCTTAAATATAAAATCTGGCAAACT
+TGTTTTGAATTTTGAATTTTTTCACATAGATACTCGGAATCAGGGGAAAA
+TTAGGATTCATTCAAAAATATTTCCCAGATTTCGGTACCCCACCTTAAAA
+ATTTTTTTTTGGGAAAACAAGGAAAATTTCTAGCTTGAACTTATTTTATC
+AATACCTAAAATGCTGAACATTAAAACACACACACCCGTATGAGTATTAT
+ATACTTCCAAGGAAACATTTGAAAAATAAAGAGTTCTCCGCTTTGATTAT
+ACACTTGTGATATTCTCACGCCTGGCACTTGGCACCAGCTCAAAGTGCTC
+ATTTTGGCTATAATTGTTTGAAGGTATATGAAAAAGTGGAAATTGGGAGG
+AAAAATGGCATGTTTTGGCTTTCTCTACCTGGCCTATGTGTTAGAAAACT
+CTTCTATGAAAATTCAGTTTAATTTTTTAATTTTTCTTAATTTTTAAAAT
+TCTAAAAATGGCTAAACTTTCAAAAATATAATTTTTAAAAAGCCAAATAC
+TATAAAATTTCTTTGTTAATTTCTTTATAACCAAAATTAACGATTTTCAA
+AAGTCAAATTTTTCAAAATTACAAAAAATTTAAAATTACTGTAAGATGCG
+CAAAAATTACAGAGTTTTCAAAATATAAAACACTCTTGTGGCCGAAAACT
+TCCAAAGTTCAGGAAATAAAAATTCCAAAAAAAAATCAAGAAAAAAATGT
+ATCTCGAAAAATTACCGCTATTAGAAAATCGCCTTCTCTAAAATTTCCCA
+AATTTTGAAATTATGGAAATTCCCAGATTTTTCAAAAGCGATCTAGTCGG
+AGTTGTCAGAAAAAAAGTTCAAGAAAACTTTCTCTAGAAACTCAAAAGTT
+GGCCTGATCAGAACTTGTTGGATTTTTTCAATTTCCCAAAAAATTTTCAA
+AGTTGCCGAAAATTACCGAAACTCCAGGGCTCACTTTTAGACCTTAAAAT
+GAAACTTTTGCCATTTGAAAGAGGCTCTTTGAAAAAGGTCTCTGCAAAAA
+ATTTAGCGGCAGACGAGCACTTTGAACTAGAAAAATGTCGCTTTGAAATT
+GCTATCATTGAAATTTTTCACTACTATAGAGGCCGGTAAAATTGCTCCAA
+ATCATAATTTAAAATATTTTTTCATGATTTTTTTTTATTTTTTCATGATT
+TTCGAGGTAGGCAAATATTCTGGGAGCTTTTTTGGATATATTTATTTTTT
+TGGAAAAAAAAATCTGAAAAATCCCACATTTCCAATAAAAAAATTCCAAA
+AAGCTTTCAGAATACTTGTCTACCTCGAAATATCCTAAAATTCATAACAA
+TTTCAAAAAAAATATAATTTGGAGCAAATTAACGGGCTATTTCAAAGTCT
+AAAAGTGAGCTATAATGCATACATTCCAGAAAATGGAATAAAAAATAAAC
+TGAAGTCAATTTAATCTAATCTCATGATACCTCCTCCTCCTTCCCCCAAC
+AAATAATGCTCAATAGCCCCCAATCAACTCGTTCCAATTTGAATAGTGTA
+TTATTTAACAAGCTTCATCATCTCTTCCTCCTATTTTTTTTTGTCATTTT
+TATCGTCCCCTCGGCCGTTTGTATTATCCTCTCTTCCTTCTTCTTCTTCT
+TCTTGAAAACGAATTGAATTTCTTCATCCAATTCACTCAAATCACATCCT
+CCACGGACACATTCAATTAATCCAAACGTCCTTTTCAATTGAACACAACA
+ACAATCACTATTTCATAAAAATTGTTTTAAATGTACATATATCAAAAATT
+GCGACGGCTGGAAAAATTAAATTTTTACACCAGAAGAAAATTTGTAACCA
+TAGTTATGGTAGCTATAACTCAAAAAAGTAGGAAAATTATGTGACATGTT
+CTCAGGACTGCAGTGATCGCAATAAAAATAAATTCTGCTGATCCAATACT
+CTTGAAATAATAAATCGTTTCTGATTGATTCCATCATTCTCAGACAAATG
+GAGCTTGGTTGAGTGCTCAATTGGTCAATGTCGCTGTCATGGCACCAGGG
+TTGTGCGGCATCCGGATTTTCTGGCAATCGGAAATTGCCTTTTGCCGAAC
+TCTAATTTTTTTTCGGCGATCGGCATTTGACGGTTGCCGAAAAACTCGTT
+TTTTCGTTTTTTCGCCATTTTTCGGCATTTTTCGGCGTGCTTAAACTCTT
+TGAGGTTTTTTTTTTATTTTTTCTTGTATTTTATAAATCTAAATAATTCA
+ATTCCAAAGTTTGATAAGGAGTGTCTTGGTTTAAATTTTCTAGCACAGAT
+CAATTTCATTTATTAACGATCAGACTGGTAGGATAGTCAACGACCCCAGA
+GGCAAGAATGATTCAAAATAATTGCACACATGGACAGCAATAGACAAAAT
+CTTTGAGAGTTTTATGGTGGGGTGGCGATGTGTCGACCAAAAGAGTATAT
+CCACTATATGGCTAATAATTCAAATATGTTGTATTTTGGAAAGTGTTAGA
+ACACAAGTGACTTGAGTGTTTTCGGATACAAGAGACACAGAGATGTCCCT
+TGATTGTTCACAGAAAGCGATTTTTAAGGGTTTGACTACAATATTTGCGG
+ATTTATGTTTCAACGAATAAATGTAAAAAACTCGAATATCATTTACTATA
+TATAAAGCGCTTATTCCGTTTTTCCATAGTTTGTAGTCTATGTAGTCTTT
+GTAGTTTGCGTAGTTTTAGCTTCTGGAGGGATAGTGAGTTGGGGTTAGTG
+TAGGGATATAGTCGGCGTACTGTAGTGGTACAATGGTGGTACGGTAGGAG
+TACTGTATGATTACGGTAGTCTCAGAAAAATTGGTTTTCAGCTCCAGAAG
+TCGGGGACCGCGCCGGAGGTGCGGTCCACGGCTGGTATATACATATGTAT
+ATGTATGTATATATGTATACATATATTCAATTAAATTTAATTTAAAAAAT
+AAAAAAAACATTTCTCACAAATGCCGAAAACACCGAAAAATGGCGAACAT
+TTTTAGGCATTCGCCGATATTTTGACCAACTATTTTTTTTTGGCGAACGG
+CATTCGCCGTTTGCCGCACAGTCCTGCATGGCACCCCGACCGGTTTCGTG
+ACAATAGTTTTGACCTGAACGCACTAGGAGTCAGGAAGTTATAGGGGTCA
+TGGGTGCTTTAATGACCCCCTGTAAAAAGCACATATATTGACAACAAAAT
+TTGCTCGCTGTTTTTTGTATTAATTTTTTGTCTCCCCTCGATGCGCATTT
+CTAGTAATGATGCACATATTTATTTTTTTTCATGTACATATCTAACAAAA
+TCATAAAACTGAAAATTGCGCTTTTGTTCAAGTTAGCAAGACAACCATTA
+TAAAGCTTTCCAAATAGCAAATTAGCAAAATAAAGTGAGAAGCTAGAAGA
+TAATGGGGAGTCCCTATAATCTTTCGGGCACACCTTCAGACTTTGTGACT
+ATAATAGCCCAAACCCACAGTTTACTGAAAACTAGGGCTTCATTTGCTAT
+ATGGTACCCCTAAACTCTTTCAGTAATCGAATCCCAAGAAACCTTCACAT
+CTGTAACCTGGACAAAAAACACACAATTTCAAAAATATAGAATTCTTTAT
+TCAAGAATCATCATCATCATTTTTTTCAATTTGTACAGACAAATGCCGAC
+CATATTTTTTGTCAGGGGAATGGCAACGGCGGGAACCCAAGAAAATCAAA
+CAAAAATATGGAGAGAAAAATGAGCCAGAGAGCCTGAGCAACCATGCATA
+AATAATGAGGAGTTGGTGAGATGAAGAAAAAACAGATAAGTTACGACGCG
+AGGAACTATTTGAAAAATAAACTGCTAAATACTATGTGCTTAATCCTCCC
+AGGTAAGCGAGTGACGGTTCTCGTATCTCAGCTGGCAGTTTCTCTTTCCG
+TACCAGTTGACGTAGGCGAACTCGGCGTCGGAGACGATGGCGTTGAAGCG
+TCCTCCGAACTTGGCCGAGGCGTCTCCCTCGATCTTTCTGGCGGCCTCGA
+GGTTGTCCTGGAAGGTATCAGTGATTGGATTTGATTTATAGTTCTTCTTT
+TTTTTCTTTAATTTCTTGCTTGTAATTCTAAAGCAACTAGAAAAAAAAGT
+TTCGGAACGCATCTATCATGCCAATTTACATAACCGGTATGGGTTTGCGC
+GCGCGGGGGGCTTGCAACATTTTCTTAAATGACATTAAGGTATGAGAGGG
+GGGGGGGGTGTTGTAAATAGGTATCCAGTTCTTGTCTGTCCCCGTTATCA
+AGTTTCTCTGGTGACGCAACGCAAGAAGGCAGAAAACAAACCTTCTCGTT
+CTTCAAAGCGGCCTCAACGATGGCGCGGAGCTCTGGATCGTCGCAGTTTC
+CCTCGTCTCCTTCCTCATCGGCGTACTCGACAGCTTCGTTGGTCTCCTGG
+AAATTTAGAAATTAGATTTTTCTCGAAATTTGGCCGAATATTAAAAAAGT
+AATACTAAGAATTTCCCCACGAAAGGCTGAAAAATTGAGGTTTCCTGGGA
+AAAGTGAAATCCCGGTCTCAAAATTTTTTTTGATTTTTGAGCTCCGTTGA
+ATACCGACAACAAAAATGGCTCTGGAATTTGAAAATTACGGGGAACTGAA
+ACGCAACTTCTACTGCTGCCAGTATGTCTCTCCCGCATTTTTCGGAGGCT
+CAATCGTAGATCAAAGTTTTCCGAATAAGTTACTATTAGGTTTTTATCGA
+GAATTGGTACTAGACTATGTTGACAAATACCAAATATCAAATATTTACCC
+AGATGCAAGTTATGGTGCTTTGAACTAGAATTCCTGGGAACTGATTGTAA
+GTGTCAAAACCTCAGCCAACCGACCTAAGCCTAAGCCTAAAAAGGTGTAT
+CGAACTTAAATTTCGACATGGCATGGCATTCAAATGGGTATACCGATGAT
+TTTGTTTCAGCAAAATTTTTAGGGTCGAATTTTTAAGGTAGAGCAAAATT
+GGGATAATTTTAAAGACTATTAATTGTCCAAAAATCCAACAAATCCAACT
+TCAAATGAGCTTAAACTTTAGATCACCTTCCCAAAAACCCACCTCAACAG
+TATCAACTTGCTCGGTGGCGGTCTCGGTGGCGGTGGATGGCTGCTCCTCA
+ACAATATCATCATAGGTGCTCTCCTCCTTGGCAGCGGCAACTGGAGCCTG
+AGTCTCCTCGACAACTGGAGCTGGAGTCTCTTCAACGACAACTGGCGCCT
+CGGTCTCCTCGATCACAACTGGAGCCTCGGTCTCAACGACGGCTGGGGCT
+TCGGTCTCTGCAACGACGACTGGTGCTTCAGTCTCAGCGACGATTTCTGG
+AACGATTTCCTCTTGGACAGTCTCGACTACGGTTGGCTCTGGTGCTTGCT
+GTGGTTCTGGTGCTTGTTCTGGTTCTGGTGCTTGCTGTGGCTCGACAACA
+GTCTCGACGACCTGCTCGACTGGTGTTGGGACTGGCCCCTGGGTGTATGT
+GGCGACTGGTGCGACTTGCTCGACAACTGAAGTGTGGGTGAGGGTGAATG
+TGTGGGTGGGAGTGGTGCGAATCTGACTAAAAACTGTAAAAACTAACCTT
+GAACAGCCTGGTGCTCTGGTGGAGCTTGGTAGTTTCCTCCCTGAGAGACT
+TGGGTCACCTGGATAGAGCTGACTGGTCCCGATTGGTATCCTCCTTGTTG
+AACTTGCTCGACTGGGGCAGATGGTCCGGCGTTGTAGCCTCCTTGTGGGG
+CGACTGGGGCTGGTTGGGAAGCTCCAGCGTATGAGGGTCCTCCTCCGATT
+GGTCCTTGGGATCTAGCGTATGAGGATGCTCCGACAGCTTGGGAAGCTCC
+AGCGTATGATGGTCCAGCTTGCGATCCAGCGTGCGAAGATGCTCCTCCTC
+CGATTGGTCCTGGACCAGCTTGGTAGGCACCTCCACCGACTTGTCCTCCG
+AATCCTTGTGGTCCCTGGGAGTACGAGGCTCCTCCGACTGGTCCAGGTCC
+TCCGAATGGAGCGGCATATCCGGCTCCTCCACCGATTGGTGCCGGTGGTG
+GTGGTGGTGGGGGTGGAAGGGCAGGCGCGGCGGCATAGCTTCCGCCTCCG
+CCTCCGGTTGCGTAACTGTAAATGAACACATTGGGAATAGTATGGAAGAG
+GTGGCTAAAGGGGGAAGCAGGTTTTAGTTTTGGCGGCCAGCAGCAGGAAA
+AAGGACATTTTGCATGAATGGGGTGGCAAGTAGAATGGACTTTGTCGCTC
+CTTAAGGAAGACATCAAAAGAACTTCAGAAAGAAAGAAATTATTTTTGGA
+ATCAGGAAAAAGCATTTGAATAGCAGTAGAAAAAATATAACAATATAGTC
+ACAAAAATACAAAAAAAAAGGCAAAATCTTACCTCGAGCTAGAGCATGGT
+GGAGCTCCTCCTCCGCACGATGGCTGGGATGGTGGGCAACATCCACCGGC
+GCTTCCGGCACCTCCGATACACGCTAACGCAGGCGACACGGCCAATAAGA
+CGGCTACCAAGACTCTCATCGTTTTTGAGAAGGCAGAAATCGCAATGGAA
+TGCTGAGTAACTGTCGTCGAATGGCAACGTAGGACGTGCCTTTTCTACCT
+GCCACCCCAAACTAACTCCGCCCATGGCCGTCTGGAGGGGGCACGCGCGC
+GCACGAAGCCTTCCGAAAGACGCCCGATCGCGTTTTATCGATGATGATGA
+TGATGATGATGAGATGAAGCCTCTCTCTCTCCGTCGGAGGGCACCTTGCG
+ACATTCACCTTGTGTGCGTGTGTGTGTTGCAGAATAGGGGGAAGAAGAAG
+CGATCGCGTACAAATGGGGTTCGTGTTCATTTCCGAATGATCCAATGATC
+AGCTGGAATATTCCTATTAATGTGACTCGTGCCACGTCATTGTTAATGAT
+CTACTATGTTTGAGTGATTGGATATGTGTTGTTTCCTTTTCTAGTTAGAT
+TCCTGAACAGTTCACCTTTACCTAATCCGTGATCGATGTTCCAATGCTTC
+TTCCTTTCACTTCCACTGCGGCACCTAATCAGGCGGAATAACATGCTTTC
+ACTCTGCCGGTAAAGTGTGAAAATCCTAAAGTTTTAGATTTCAAAGATTT
+CAAAAACGATCGTTGATCCTACCGCGCTTCCGCATCAACTGATATCAGGT
+TTTTTTTAATGATAAGATTGTGGAGGAATGAACTGGTGAACTTTTAGGCT
+GATTTAGAGCCACGTGGAAACTTCCAGCTTTTACCTAGGTGACTACAAAC
+TACGGAAGATCAAATTACATACATTTTGTAAAAACATACATCACTTTCAA
+AAATTTCGGTTTAGTTCAAAAAATCACATTTTTACTGTTTTGAGATTTTT
+TTTTTCCCAAAAATGTCGATGCAATTTTGATGTCGATGCACCACGGGCGA
+TTTAAAGGAAATTATCAGTTTTCTGAATATTTTTGTTTTGTATGTCTTGA
+TTATGGGTTTTGTAGGCTTCGATGGCAGGCAGGCGAGGTTTCGGGTCCTG
+GCGCCCGTCTGAAACCTGCCCGCTTCACGCCGGCCTTTTGCCTCTTTTTT
+GCATTTTTACGTGGTGCCAGGCTGTCCCATCGCAGTTTGATCTACAAAAA
+ATACGGGAATTTTTCGCCCAAAAATATGTGACGTCAGCACGTCTTTAACC
+ATACGAAATCAGTTGAGTCTCTTCTCCCGCATTTTTTAGTAGATCTGTGT
+AGATCAAGCCGAAATGAAACACGCTGACACCACGTGTGTTTCTCATTGGA
+AATTGGAGGCCTAGAAAATCAAAAGTTAGGCCATCAACAGATTTTTGTTT
+CAGCAAAAGGCGCGGATTGAGGCGAGGTCGCTTTAAAGTCAGGCAGGCAG
+GCGGTTAACGCCTACAGGAAAACTTTAGGTTTTAGGTTATCTGTATGTTT
+CCCTTTTGTGTGTTTTTTAGACGTCCAAAGAATCGTATCAAAATGAATAG
+GTATTTTCTCGTTTTATGCAGATAGGTAAAGGTCTGTAACCTGAAAATCC
+AGAGCCTTATAATCCACACCTACATAATCATCAATTAAAATATTCAGATA
+ACTGATAATTTCCTGAAAATAAGATATCTGTAAATTGAATCAACGCCAAT
+TTTAGACATGGTGCATCAAATGCAACATTGTATTGATATATAAACTTTGG
+CAGTCAATACATGTTTTCTTATGCATTGTTCTCAGTGCACCTTGATCAAT
+TGAGTAGACTTCATCTATTCTTGTCCACTTCCTAAACATGAAATCAATCA
+CGGCACCCCATCAAAAAGCACTAAAAAAGTACATTTAAAAGAGTACATTA
+TTATTGCCCGTTCAATCCTCGTAATGTATCTTTGCAAGTTCCTTCTTCCT
+CTGACATTTCCCGTTCCAATTCTCCGCCATACCTGATATGCTCGACTTTT
+TCGATCATAGACGCGAATTGCGCAACGCGCGAAAATATCTTGCGCAATGA
+ACAAGGAGAAGAAGAAGAAGAAGAAGTAGGAGAAGCCAAATAAAAGATAG
+GTGATAACCGAGATGTTAAGCCAAAGAGAAGGAGTGTAATAGCTGAACAA
+GGCCTATTTTTGTGTAACTCCCCCCTCTGACAGCTTCTTCACTTTCCCTC
+CAACCGTTTTTACTCTGTATGGTAATTGTTGATGGATCGCCATGGAAAAG
+CCCTAATGGTCATGAATAAGCTGTAAAGCAGCGGGGGTGAGCTTGAAGGA
+CGATCGGACAAATGAGATATGAAGCGTGAAAAACGGAAAGCATGCTTAGA
+GGGGGAGATATATGTAGATTTGGGGAAAAGCTACAAGGTCGATTTTTATC
+CGGTGTCAGGATTATAGAGGTGTTTTGAAGTAGAAGCAAGGCACTGAAAT
+TCACCACTTCCTCTATTAGAATTGCACATTTTTTAAAACTATGTACCTGT
+TTTCTTAAGAATTGCTTGAAAAGTTGAATTTGAACTAGTAGTTCTTGCAA
+AAAGGCCAATTGAACTATCTGGTTTAGTTGCGTCCTTATTAATATTGCAC
+TTTTTAATTCCGGCAAAACGCCGGTTTACCGATTTGCCGGGGATTTTCAT
+TTTTGGCAAATCGCCGATTTGCCGTTTGCCGAAAAAATTTTTAACAGACG
+GAAAAACTTAAAACTGTGTCATTTTGAATTTATTACCGTTTTCTTTAGAT
+ATTTTCATAGAATTTGCTAACTTTTGAAAATAGATGAAGGAACATTTATA
+TTATTTGAAATTGAAATTCTGAAACTTCCAAAAAAATAAGTTGCAAAACC
+ACAATTTGCCGAAATGCCGTTTTCCCGGCAAATTCGGCAAATCGGCAATT
+CGCCGATTTGCCGAAAATTTCAATTCCGGCAATTTGCCGACAAAGCAATG
+TTTCATAATACATAAAATGTTTCTAATTTTTAAGAATGATTTTTTTAATT
+TTGACAAAGTTTTTTTATAAAAGAGCCGAATTATTTTAAATTCCCGCGCA
+AATAAGTGACGCCATTTTTTACATTATTTGTATTTTCTGGCTAAATTAAT
+TGGTTTATGTATGTTTTTTCTTTAGTTTATAACTTGAGTAAAATTCACAG
+TAAAAATTAATTTTGAAAAATCGATTTTTAGTTTAATTTCAATTTCAGAG
+TTTCGGCAAATGTATTCTCAATTAACAAGTTTTCCAAACGGAAAAAAATC
+TGAAAATTGACAAACCACGGTGTAGATCAAGCCGAAATGAGACACCCTGA
+CACCACGTGTGTTTCCCCTTGGAGGCCTAGAAAATCAAAAGTTGGGCCAC
+CATCAGGTTTTTGTTCGACTCAATTGGTAAACTTTGCAGACTAGGCTGAA
+ACGTGGTATTTGCAAAAATACAATTTTACACATTTATTTTCCACAAACCG
+AATAAAATCCTTATCTCAACAGTGTTATATAATTTTTTTTTTCAGATCAC
+TATCACGACATTTTAAAATATATTACAGCACTCTCTTCTTTAGGTTTTGA
+ACGTTGATGCTTCGAGGATAAACATGAAAACCAGATCAGCTTTTCCGTGA
+CCTCACATACTCATTTTCTCAAATTCTCAAAAATGTTCTGCCTTCTCCAA
+CGGTCTCTAAAAAAGCTTGGAAAACCCACAAAAGGTGTCTTGGGACACTT
+CTGTCTCTCTCTTTATCGATGACCGGATCGCCCGGATAAACGGGTTTTGC
+GGACTGACACCAGCAGGTGGAAATGGGCACACTTGTAAAATAAAACGAAA
+AATAATAATAAAAATAACACGGAATGCGGAGAGAAGTGGCAAGATCGGAA
+GAATGGTGGGGGGGGGGGGGGGGGGGATTACATAAAGATGGCGGCATAAA
+GTGCGTTTCATTAGGGGGATATTGGGGTTTTTATAGGGGGAAACTTTGAT
+TTTTTTGAAAAAAAAATTAAGAAAGAAGCGACAACAACCAACAACAAGGT
+CATTTTTAAAAGGAAAATTTGGCATGAAATTTACATTTTGGGATGAATTA
+TGAGGATATACTCATATAACCTAATTTTGTCACAAAAAAAACGTCGAAAT
+TTTTAAAAATGACTACATTCTGCAATTTTGAAAAATTTGGTGGTCCTACC
+ACGAAAAATCCATGGTTTTTTGGTATTTTGACGAAAAACTGATTTTTTGT
+GTTTTTTTTCTGGTATTTTGAAGCCGCTGTACTTCAAACCCTTTTCATAT
+TCTAAAAATATCTTTTTGCAAAATTCGGTTTTTTCTAAAGTTCAAAATAA
+ACCACTATTTTCAATTTTTAACGGAAAATCTGCAAATAAAATTTCGGAAA
+ATTCCGGCAATTTGCCGATTTGCCATAAATTTCAAGTTCCGGCAACTTGC
+CGATTTGCCGATTTGCCGTAAATTTCAAATTCCGGCAAATTTGCGAATTG
+CCGTCCTACCATGAAAAATCCTTTTTTTTTCTGGTATTTTGAGACCGCCG
+TACTTCAAACAATTTTCATATTTTACAAATATCTTTGAGCGAGCGGTTTT
+TTTTGAATTTCAAAATAAACCAAAAGTCTACTTTTTTTGGTTTGTTTTTG
+TAATTTTTTTTTTAGAAATTTCAATTTTTATCGGCAAATTGGCAATTTGC
+CGGTTTGCCGGAAAATTTCAAATCTGGCGATTTGCTGCTTTGCCGATTTG
+CAGGAAATACCTATCCCTGATGTAAATTACCAGAATTAGAAGTTTGGTAC
+ACGATTGGCACACAATTTTTTGGTACAAAACACGCTAAAAATTAAATGTT
+TTTGAAAAAAAAAATTCTTTTGAAATTGTTTTAGTGTGAATTTCCATGTA
+TTCAATTTTTATCATTTTTAGCCTGTTGCTCCAAACTAGGTTTTCTCCCA
+CGTGGCATCTCTCATTACACATAAAAATACCTGCTAACTCAAAACATTAA
+TCAGAGATCCATATCCATGTCTTCCTCACTTTCCAACTTTTTCCCTCTTA
+GCTTATCTAGATATATGTAGGTATATCTATATCTACAAACAACTTTCTCT
+TTTCAAACATCCAGTTTATCTTCTGACCTTTGCAACATTTTTCCTTTATT
+CCAAACTTCCGCCAGATTGCATCTTATTCAATTATTACATTCAAAGAGTG
+TCTAAAGTTTTGCTTAGAAGAAACAAAAGGTAAAATGTCAGATATGTTTA
+GAGAAGGTTGTAAAATTTGGCAATTTATTGTAAAAATTCGCAATTTTGAA
+ACTCCTTTAAAATGGTTAATTTTGTAGTTAGAGGACTCAAAATTAATGCC
+CGAGAACTAAAAAGTTGTCATTTTTCATTTATCAATGATTTTACTTAATT
+TCAAAAAAAAAATTTTGCCCAAAAAAGGACAGTCATTAGAAAAAAAAACG
+GAAAAATGATATGGAGTGATTCTTTTTTATTTTATAAAATTAATCAGCAT
+AGTCAAATGTACCAGAAAAAAGCAAATAAAATGTACTAGATTGACCGGAA
+GATTATTTGAAAAATTGCAGAAAATGCACCAAAAGCTGCTTTTTTCAAAA
+ATTCAAAAGTACGGTAAAATCATACGGAGCTATTCTTTTTTATTTCATAA
+AACTCTTCAGCATAGTCAATAATACCAGAATATGTCAATCAAAGTATAAT
+AGCTTGTACGGAAGTATCTTTTTAAAAATTGATAAAAATATATAAAAGCT
+GTTTTTTTCAAAAATTCAAAAGTATGGGAAAATCATAAGGAGTCATTCTT
+TTTTATTTCATAAAACTCTTCAGCATAGTCAAAAATACCAAAATATGTCA
+ATCAAAGTATAATAGCTTGTACGGAAGTATTTTTTTAAAAATTGATAAAA
+ATATATAAAAGCTGTTTTTTTCAAAAATTCAAAAGTATGGGAAAATCATA
+TGGAGTCATTCTTTTTTATTTCATAAAACTCTTCAGCATAGTCAAAAATA
+CCAGAATATATCAATCAAAGTATAATAGCTTGTACGGAAGTATTTTTTTA
+AAAATTGATAAAAATATATAAAAGCTGATTTTTTCAAAAATTCAAAAGTA
+CGGGAAAATCATAAGGAGTCATTCTTTTTTATTTCATAAAACTCTTCAGC
+ATAGTCAAAAATACCAGAATATGTCAATCAAAGTATTATAGCTTGTACGG
+AAGTATTTTTTTAAAAATTGATAAAAACAAATAAAAGCTGATTTTTTCAA
+AAATTCAAAAATTCAAAAGTATAGGAAAATCATATGGAGTCATTCTTTTT
+CATTTTATAAAATTCTTTAGCATAGTCAAAAATACCAGAATATGCCAATC
+AAAAGATAATAGCTTGTACGGAAGTATTTTTTTTTTAATTGATAAAATAT
+ATAAAAGCTGATTTTTTCAAAAATTCAAAAGTACGGAAAACTATATGGAG
+CGATTCTTTTTTCTGTTATAAAACTGTTCATCATTGCCACGTATACCTGA
+AACTACCAGAAAAAGTATGCTAGCATGTACGGAAGATTATTTGAAAAATT
+GCAGAAAATGCACCAAAAGCTACTTTTTTCAAAAATTCAAAAGTATGGAA
+AAATCATATGGAGCGATTCTTTTTTCTTTTATAAAACTGTTCAGCATAGT
+AAAATGTACCAGAAAATACCAAAAAAAAGTATGCTAGATGTTCGAAAAAT
+TGTTTTTATAATTTTTGAGAGGAGTTTCAAAATTGTGAATATTTACAAAA
+AATGGACATTCTTGCCACTTTTTACTAATTTTTGATGGGCTAAACCTAGA
+TTTTCTAAATTTTACATTTATGAATTACCCGTTTTCGACGAATTCAGGCA
+AATTTTTATTTTTTCCTATTTTTTTCAGCCATTTAATCAGCCATAATAAT
+GAATGTCCTTTTTTTTTGGGCAAAAAAAAATTTTTTAAGGCTCGAAGACC
+AATTTTAAGTTCTCTAGCTACAAAATGAACCATTTTAGAGGAGTTTCAAA
+ATTGTGAATTTTTACAAAAATTGCCCAAATTTGCCACTTTGTAATGGTTT
+TTGGTGGGTTAAACCTAGATTTTCTGTATTCTGCATATATGAATTACCCG
+TTTTCAACAAATTTTGACAAATTTGTATTTTTTCCAAAATTTTTTTTCAG
+CCATCTATTCCTTTTTTTTGTCTGTTTTTTTTTCGGGCAAAAAAACCTTT
+CCCCACTGGTGCTATACCACCTTTAACGGTAAATTTTACTGGTCTAAAAA
+TCGGCGAAAAAATGAAACTTCAAGTAATATAATGGTAATTGAGTTTTTTT
+TTCTATTTTCTTTGTTCAAAATATCAATTATGACAAAAAACGAGAAAATT
+ATATTGACACAGTTAAGCGGATATAAATAATAAAACATCACAAGCACATT
+TAATTTTTCAAACCCCCTCAGGAGTCATGAAGAAATCCTTCTCTGCACAT
+CTACCTTTCTCCACATCCAACTCCTGATTTATTTTCTCCGCAAACTCCGT
+GTAACTTTTAATTGCAACATTCAAAAGTTTTGTATGATGCTTCAAGTGAC
+CCAAGTCGATTACACAATCCCCGCAAAGAGCTTCGCTGCGAATTTTGTCA
+ATTCCCTCTTCTAAATTCACTTGTTCTCCAAACTTCACTGATTTCCTTAG
+GATCCCAGTGCTCAGGCAACAGTTTGTGCAAATTCTCAAGGTTTTTGATT
+TCAGTTGGCAAGCGGTGCAGATAGGGCTCTGGAATTTTAAATTATTGATT
+TTTTTAAAAATTATTAACTCACCTCGTCGCTTTCATGTGCTCTTCTTGGA
+TTATGGTCATATGGAACTAAGAATCTCGAAAGTTGTATTAAATCCCACAA
+AGATCGATTCACATTTTTCCTTTCAAACGCATTTTCTCGTTTACAGTGTG
+GACATCTCTTGTTCAGTAGTTGGAGTCGGCATCTGTCGCAGATAGTGTGA
+CCGCAAGTGCCTATACAAGGGATTTGGGTATCATGATCTGGAAAATTTGG
+TGTGTAGGGCTTCCATGGTAGGCAGGCGCGGGGCCTGGCCCGCCTCACAC
+CGGTGAATTTACAAATTTTTGATTTTCTCGTTTTTGTCATTTTGATGAAA
+AACATTGAGGCAGGCGGAGGTCGCCTCAAGTTCACTCGGCGTTTGCCGCC
+AGCTTCCTACCCAAAGCTTTGCAACTTCTTACCCAAGCCTTGCCCAAAAA
+ATAAAAAGCTTAAATATCAAAATTACTCAATTTTGTGTCATTCTACTAAT
+TTTCTGAGAAAATTTGAATTCCCGCCAAAAATTTTATTGGAAAATTTGAA
+CTACTGGCCAAAATTTTTTTTGGCTGCGCCAAAGATGATCTTAGAAATTT
+GAATTCTCGCCAAAATTTTTCCCAGAAATTTGAACTTCTTGCCAAAAATT
+TTTGTTGGATAATTTGAATTTCCGGCAAAAATTATCTTATAGTGAGGACA
+CAATCAATAGTTTTGGTCAAAATTGTATTGTCAAATTTTTGATGTGTGTT
+GGCAATTTTGGCAAATTTGCCGAGCTCGGCAAATTCGGCAAATTTGCCGA
+GCTCGGCAAATTCGGCAAATCTACTTTTTGAAATTCGCCAAATTTGGCAA
+ACGGCAGAAAAAAGTACAATTGAGATTTGAGGTACACAAGACTTACATCG
+AAATTAATCTAATTAAAAGAATATCACTTACCATATTCATCATAGCATAT
+ACTGCATTCAGTAACCTTCATCGCAAAAATAGTCTAGACACTGACCAAAC
+ACTACACACTTGATGCTATTTATATACTTTCTATGCTGAGCAATACAGAA
+CATGCGATGTGAGGAATCTTAGGTAGCAGAAGTACAAAAAGATTGACATG
+TGATTAAATTCCTAATTTGTTCCTTATCACATTTCCCATATGTCAATTAA
+TTCGTAGATAGATGCTATTGATAAAAGTTTTTCGAGAATTTGTAAGATAT
+GAAAATAATATTCCTCATTTTTAATTTAATGATACAGTACTTTGAAAATT
+TCAACAATTTCAACAATTTTTAACACCTATGTTATCATTCATATACAACA
+ATTTGTTTAATACAGTAATACATTTCCACCCACGTGGTATTAATACAGTG
+TTAAGCTTGTTATTTTTTAAGGAAAAATTTAGAAAATTTTTCTTCCTCAT
+TTTGCTTACTTTTCAAAAAAGCGTGCAACTCCCTCATTTAAAAAAGAAGT
+GTCGTCGCTGAGGAAAATGTTAAAAATTTCTCTCATGGTGCTAAAATTAC
+TAACTAAAAACAGTAAGTATCGTAGCGAAACATTTCAAAAATTTTCAAAA
+TTTTTTATTTATAGTCAACAGTTTTGGAAGTCAATTAAAAACATTTTTTA
+CTATTTTTAATATTTAAAAACGTTTCAGTTGCTTGTAACTTTATAAGTTT
+GCCTACCGTACATTTACCGTAAAACAACCTTAAAAATGTAAGCTTTTCTC
+CCGATAAAAATCTTTACTCAGGAGTTCGCGACTCTTCTCTTACATTAATT
+TTTTCTCTAATATATTGAGCTCAAACCTAGCTGTAAAATTGAACATACAT
+ATAACTTTGAGTGCAATTTAAATTTCAGAAAACTTTCACAAACCCAAAAA
+TTGAGAATGCTCAGGACAGTTTGACCTTTCAAGAAAATTGCTTCGAGAAA
+ATTCCAAGCTTCACAAAATTGCTCATTGCCAAGTTATTTCCTTTAGTTTG
+TGGCCAACGCCTTAAAAAATACAAATTAAAAAAAAAACTCTGACACCACG
+TGATGATGCAATCAGACTCACGAACTCACGGGGTTCTGCCCTTCCTCATT
+GAATTTTTCGCGCTCCATTGACAATCACCCGCCGTACAACACGTGGGAAA
+GTCGTGCACTCCACAAGGACAAATACATTTAGTTTTACAACTAAAATCGA
+GCCGCGACGCAACACGCAACGCGCCGTAAATCTACCCCAGATATGGCCAA
+GCCGAAATGGCCTAGTTCGACAAACTCTTCCATTTCAATTTATGAGGGAA
+GCCAGAAATCCGTGCGAACTGCGAGCCTAACGCTCTTTTTCAAAATATCG
+TATAACTCGGAAAACAAGCCATATTCCCAGTTCCTGTTTTATTTCGAAAA
+ACAGATAATACAAAAGAAATATCTGAAAATTAAGAATAACATGTTTTTAT
+TAAATACTTCTTTGTCTATATTCCATATAAAAAGAACCCCATGCGAATGA
+AACACTCACTATACATTCAAAATGAATTTCGCCATCTACCTTCTCGCTTT
+CATCGCCTGTCTCGCTAACTTTGGATTTTCACAGGGTAATCCAGGACTCT
+CATTTGATCCAGAAGAAGATTCAGTAAATATTGTAAGTTTTCGGATTAAT
+GGTTACAACATCTATAAGATTGTTTAGAATGGCAAAGTGCCAGTGGGAGC
+AGTGAAGACGTTGGTTAATGATCTTGTGAGCCCTACTATTGCAATTGTGG
+AGAAAACATTATCCTCATTGTCAGTTTAAGGAGCTACGGGAGGGCTCCAT
+CCATCTCAAATGTTTCAAATAACTCATATTGTTCTTTTATCTGGGAGTAA
+ATAAATTACATATTGGGAATCCTTTTCTTTTTGTTGTTAACCAAGTTGCC
+GGTTGCCAAATTTTTTTGGGTTCGGCAACTTCGGCAACTGCCGGTATCAA
+TGTCAAACATTTTGAAGCTTAGAAAAAAGCATTCAGAGAGCCTGAAAAAT
+TCTATAATTTCACTTTAAACGAAAAAAATACCATACTTTTTTACCAAAAC
+GCTCAAAAATATAATTTCAACAAAAAAACATTGAAACCTGGTTGCCGAAT
+TTTTTTGGGTTCGGCAATTGCCGGTTGCCGTTAACCTCGGTTGCCGCACA
+GCCCTGATGTGGAACTCTGCAGGCCTAGCGGCATCCATGTGAAGGAAGCG
+TATTGTATTTATTTTTAAACATAAATTAAAAAATCGATAAAACCTTCATA
+TATATAAATTGTTTAGACCGGTGAATAAAATGAGACGATGCCACGCGAGT
+TGGCGAACGCTTTTCTCCGAAGATCCAAGTCAGGACGTCGTCGATGGGCG
+GGACCCGGTGGGCGGAGCTTAGTCGGATAGCGCAGCAGACAAAATACGGG
+CGGTGCGTCGAGATCAAGTGCGTACTCCTCGACGGAAAGGGAGCTTGACG
+CGTGGATTGCGTTCTCGTCGGATGAGGAAAGATCTTCTGAGGAGGCGACC
+GGAGCCAGTGGTGGGAGCTCTTGTAAAAGGCGTTCTCTGAAACAAATAGT
+GGTGTTAAGGGGAAATGCGATGGGAAATCCGAGTAGTTGATGTCCGCGGA
+ATTAATTTTCTCGGGGTTTCATGGAAATTTAATTCCGCGGATTTCAACTT
+GCCGAGTTTTTATTCGATTTTATGAAAAAAATTACACGAGAAATTGTTTT
+TTTTAATTAAAGTATCCGAAATCCCCGGAAACAGATTTCCATAGAGAGAG
+GTCACTAGAGGTTTCATGGAAATATGTATTCAAGGTCTTAAACTACCCAA
+TTTTTTTACCTCGATTTTAACAAATTTCAAGTAAATTTGAATAATTCTAA
+CCAGTTTTGTTGTTTTACACAAAAATTCGGGTTCTTTAATCCGCGGAAGT
+AGCTTTCCAGAGGTTTCATGGAAATATGTTTCCGGAGATTTCAACTACCC
+GAGTTTTTTATCTCGATTTCACACATAATCGGCATAAGAAACTACAATTA
+TTTGTTTTCGGGGAAACTTTAAAAAACCCCAGAAAGTTGAATTTCTAGAA
+ATTAGCTTTCCCGAGGTTTCATGGAAATTTGTTTTCGCGGATTTCAACTA
+CCCGAGTGTTTTACATCAATTTCATCATAATTGACATAAGAAACTACAAT
+TATTTGTTTTGGGCGAAAGCTAAAAAATCCCCGGAAATCTGGATTTCTAG
+AAACTAGCTTTCCCGAGGTTCATGGAAATTTGTTTCCGCGGATTTCAACT
+ACCCGAAATTTTAATTCAATCTTTAAAAAACATCCAGTTTTTGTGACATG
+TTCTTCAGTTAAAAAAAATCAGAGTGTTGGAATCCTAAATTTCTAAATTT
+TCATAGTTTCCGCGGATCGAATTTCTAGAAATTACCTTTCCCGAGGTTTC
+ATGGAAATTAGTTTCCGCGGATTTCAACTTCCTGAAGTCTTCATTGGATT
+TCAATATAATTCGCACAATAAAAAAAGCCAAAACGCGAGGATCCCTGGTA
+GTTGAAATCCGCAAGAATAGTTTTCTCTAGTTTGAAAAATTTACTGAAAC
+CCTTACTTTTGCTTTCCCAAGAATTCGAGTTGTTCCTCGAACAATTGCTT
+TGCAGTCCCAATATTCGGCGAAAATTTCGATGGTTCACTATTCCGACGGT
+GCTCTTCAATTTTTCGCAAGTTTGCTGATACCTGAAAAATCGATATTTCA
+GACTATCTGTGCCAAAAACTAATTTATTAATTTACCTTCTGACTAGCATC
+CTCCAGCTCAACAATGTTATGAATGGTGGCTTTATACTGTTTCAGCTTCT
+CCTCAATTAAAGTCTGAACACAACCCGTTTGCCGTGCCACGTCATTCAAC
+TGCTCCTGAGCATGAGCACTATCTTGTCGGCGGAGCACACATGGCCCGAA
+GATCAGAGCCAAGTTGTTGCAGCCCATTTTGTTGACGGCTTCCTGGTCGG
+CGACACGTGCCAAATGATACATTAGGCGATCGAGCACGGCGCGGTTCGGT
+TTTGGGAGAAGCTCGATCATTACGGAAAGACAACGGACACGTTCACCCAT
+ATCCTCCACTTCTGTAATTTTTTTTTTTGGACGAAAAAAAACAACAAAAA
+ATATCATTTTGACAAAATGTTAACTTTCAGAAAATTTGAAAATTGATTTA
+TTTTTTTTGTTTCAATTTTTAGGTTTATGAATGAATCCGATTTTTTTTTG
+TCGAAATTTTTAATAAGAGCCCTAGTAGGCATGTGGTGTGTGTGTGTCTC
+ACTTCGGCTTGATCTACGTAGATCTACAAAAAAATGCGGGAGAAGAGACT
+CAGAGTTCTTAATGGATTTCGCATGGTTAACAATATGCTGACGTCACTTT
+TCTGGGGAAACAATTTCCGCAATTTTTTGTAGATCAAACCGTATTGAGAC
+AGCATCTCTGCCTGGCTGCGGACGCCTCGTTTTTCCCTTGGAATTTTTTT
+GGCGCGAAATTCAACTTTTCAAGTAAGTGCGAATATTTTCAAGTGAGACT
+GTTCAAAATTATTTTGCTGCCAAATTTGAGTTTGCAAATAAATTATTGAG
+CAAAATTCAAATGTTCAAATATTTTCTTTCGAAACGTAATGAAAAAACTC
+AAAGTTACAAATAATTTGGCGCGAAATTTGAGTTTTCAAATATTTCTAGT
+GCAAAATTTGAATTTTTCGAATAATTCTGGTCCAGAATTCAAAAATTAAA
+AAAAAATTAGTTTGAAGCGATGCTCAGGTTTTCATAGAGCTTCCATGTAG
+GCGTTAAAACGCCTGCCTGCCTGCCTTATGCCGCGCCTAATGCTTGAATA
+TACGTAAACTTTTTTTCATTTCTTAATTTGATTTTCAACAAGTTGATAGA
+ATTGAGAAAATTATAAATTTGTAAATTTACTTAAAAATGCAAAAAAATAG
+GCAGGGTTCAGGCAGGTGCCAGGCCCTGAAACAGCGCCTGCCTACCATGA
+AAGCCTATCGTAAAAAATCCAAATTTAATTTTTAATTTTACTAAAATTTC
+GATGGCTCGTTTTTTTTCAAACATCACAAACCTGAAACATTCAAAAAATT
+TTCATAGAGATCAAAAATGATAATTGGTTCGGCGAGTTCTCGGAAGAACG
+CCTTGACAAGTGTAGTTAGCACATGAACTCCAATATCCTCAAGATTCACA
+GAATCCGCATCTGAAACTCCGAATTTGATTTTTTTTTTTTCAATTTTTCT
+GCAGTTCAACAATTACCTGCAGTCGATTCAATCACTTTTCTGATACTTCG
+AACTTGGGGTAGAGATCCACTTTTTCTGAAATTACGGGCGCAAAAATTTC
+AATTTCAAAGACCTTCAGGTATTTCCGTACCTATAAACTCCTTCCACAAA
+CAGGGCACGTGTCTCAATTGCAAAAAAGAGTCGGTCCAAGAGTGTTGGCA
+CAGTATGATCATCATCGACAATTGATACTAAAGAGGCGCCAAAGAATCTT
+CCACCATTTGTCTGAAATTCAATATTTATAATAGCATTATAATAGCATAT
+TTGGCTGTAGTTTGTAGCAGGGGTCAGGCAAATTGCCGATGTTGCAAATT
+TCCGGCAAATCGGTAAACCGGCAAACTGCCGGTTTGCCGAATTTGCCTAA
+AAATTTTTGGCAACTTTTTTTTGGAATTTTCAGAATTTCCATTTTAATCG
+GCAAAATTTTACGCATCGTATGAATTTTCTTACATTTATTTTGAAAAGTA
+AGCAAATTCTATGAAAACATCTGAAGTAAACGAGAAAAAAAAATTCAAAA
+AGGCACAGTTTTAAGTGTTTCCGTCTTATAAAAAATCCCTCTAAACATTT
+CCGGCAAATCTGATATCCGGCAAATTGCCGGAATTGAAAATTTCCGGCAA
+ATTTTGATTCTGAATTTTTCAAAAAAACTGTTGGCAAAATACAAATTTTA
+TTTTATTTTCAAATATGTTTTTTTTTTCAGAAAAGTAAATTTTTTGCCGG
+GAATCAAATAATTCTTGAAAATGTTTCAAGATTTTTTTGCCACGAAATCA
+GACGTTTTCAGAACAGTTTTAGCGGAAAGTTAAAAAAAAATTTCAAAATT
+TTTGGCAGGAAGTAAATATTTTTCAGAACATTTATCCGAACAGTTTTGGC
+TGTAAATTCAAATGTTTAGTTTTCAACAACTCTTAGCGGAGAATCCAATA
+TTTTTCAGAATTTTGGAAATTAAAAATTTATCGAAAATTAATTGCAATTT
+CTAAGAAAGCAGTTGTAATTTTTTTTTTCAAAAAGCTACCGAAAAAATCT
+GGCAAATTTGGCAAATTTGCCGAGCTGAGCAAACCCGGAAAAACGCAATC
+ATTTTCTATACTTTTTGGATCATCAAAATTACTGAATTCCTACAATTAGT
+ACACGTCAGATTTTTCTATAAGCTCCGTTTGGTCTACTTGTATAAAGCTC
+GAAATATCTCAATGTTATGTTATTTTACTAGATTTTTTTGGAACAAAATC
+AATAATTTCGGTTAAATTATATTGTTCATTTTGTGGTGTGTGCGTGAAAT
+TTCAAAATTTGCCGAGCTCGGCAAATTCGGCAAATTGCCGCACACCCCTG
+TATTACTCACCTTCGGATCAATCGCCTTTCCAGTCATCTGACACGGATGT
+GTGACCTTCGGCTGACACTTTTTATGACACGATATCCGGCACGCAACACA
+AGTGTACAGCTTCTCATGGTGCCATATTAACTGATTACACACTTCACAAT
+AAGTCGGCACATGGACTGCTTCGGCACGGAATCGGTGACCAGCATGTACC
+TGGAATATTGGAATTGCGTGGGCAGGGGAAACTAGTTTCATTGAAAATTT
+TTTTTTAACTGCTGAAATTAGTCCAAAATGACATGTTATATGTACTTTTC
+TCAAAATGTGTGAAAATTGCACACTGAATTAATAAATAATATTATTTTTG
+TAAAAACATAAAAAGGGGAAAAGTCAGCGGTAAAAAAGTAAAAACACTCA
+GAGTTAGATCTTTTGACCTCCAAAATCCATGAAAATTTGCTTCATTTTTT
+TCATAGCTGTGACGTCGTGGGCGGCAATTTCCGTTCGGTAAATTTATTTT
+CGGCAAATACGGCAAATTGCCGATTTGCAGTTTGCCGGATATCAATTTGC
+CGGAAGTTTTAAAAGGGATTTTTTAAAAATTCCAAAACACTTAAAACTAT
+ACTTTTTTGAAATGTATTTTTACTATTTTCTCTAGATATTTTCATAGAAT
+TTACTTACTGTTCAAGCCCACAGCTTGCCGAAAATTTCCGGCAAACTGTC
+GGTTTGCCAAAATTGCCGAAAATTTAAGAAACGGCAATTTGTCGGTTTTG
+CCGTTTTCTAAAAAAATTTAAATTTCGGCAATTACTGTATTTGCCGTTTG
+CCGAAAAACTAAATTTGCCGCCCATCGTCACACAATACAAAAAAATTGCG
+CGGCTTCTGGAGATCAAATCTGACAGCTTACTGTATTTATAACTACAAAT
+TCACGCTGTGTTTTTCTCTAATTCACGTGGTGTCAGGGTGTCTCACTTCG
+GCTTGATCTACGTATATCTACAAAAAATGCGGGTGAAGAGACGCAAGAAT
+GTGCTAACGTCACTTTTTTTTTGAAAAAAAAAAAATTCCCGCATTTTTTG
+TAGATCAAACCGAACCGTAATGGGACATCCTGGCGCCACGTGCTAATAGT
+AAGTCACTACATTCTTACCGCCGCTACATCTGATTTTACACGCTTCTTTC
+CAACTTTCTGAATACCAATATTTTACACAATTTTCTCGGATTTTGATATA
+TAATACTTTCGCGGGCTTCTGGCTTCCCTCATATTTTCAAATGTAAGAGT
+TTACCGAATTAGGTCATTTGGGCTAGGCTACGGCGCGTTGCGGCTCGGTT
+TTCATTGCAAAACTAAATGTATCTGTCCGATTGTCATTGGAGCGCGAAAG
+GAAAGCTAGAAGCCCATGTATTAAAAAATCGACTTACCTTTATCATTGAT
+GACTTCTCCTTCCCGCGCTTCTTTTTCGATTGCACATGAACGTATTCGTT
+CAGGAAACCTCTGGAATTGAAAAAAATTGTTTTGTTACAAACGCGCCCTA
+ATAACAATTGATCGTGTATTCCACGTTGGAAATTATACAAAATACAATGG
+AGCACTTTTGCTCGAAGCCTAACATTTTCTAAATGTTTTCTCACCTAAAA
+GCGTTAACGCCAAGTGTTGTCGGAAAGGACACACTCTCCTCGAGACAGAC
+TTTCGTTAAAAGTCCCTCGAACATTGTGATGACGTCACGGTATTTAAGCA
+CGGATTGCTCGACCTGAAATGATATGTTGCTAATTACACTTGCGTGGCCG
+TGAACCCCAAAAACTAGGCCACCTTTTGCGCCCAATTACCGATAAAACCG
+CCTCATATCCCAACAGCTCCATATGGAAAGCTCTTAGCGACTTTTTGAAG
+ACCGCATCCACTACAGTATCCCTTTTGGCATTACTCTCGTTTAGATGACG
+TGTCTTGTTGAAAATAAAAATACTGAATTGTCGGAGATCGTCGGTGGATT
+CTACAAGCATGTTTCCAGGGTCGATCTGTAAGTATTGTTTAAGTACAAAG
+TACTACTGCTTCAGTAAGCATTGTAGTTTATAGTTTGTGGTTTGTGTTTT
+GTAGTTTGTGGAGTTTTTAGTATGTAGTGTGAAGCTTGATATTCATTTTG
+CAGTACATTGACTTGGATTGGGGTGTGCTAAGATATAATATCAAAGTACA
+AACAACGAGTGACAAATTAAACATCTCAATCCGAAAACTACAAACTAAAC
+CCTACAGACTACAAACTACAAACTATATCCTACAGACTACAAACTACAAA
+CTACAAATCACAAACTACAACCACGCAAAAGAACGTTACCTACCTGTTGC
+TTGGTTTTTGTTAAACTGAACGTGCCGGTCGATGGAATTGGTGAGGAGGA
+TTGCCGCTGCTTGTGGGGCCTGGAGTTTCAATTTTTTTTTGTTTCAATTA
+AGATTTTCCTCAAATGTTCCTTACATCAAATCCCATGGCCGTTTCGGTGA
+ATGCAGCCGAGTTGGTGATCGAACTGGTGACGTGGGATTGCACGGGATGG
+AGGAGGCGAAGACGAAGCATTCCTTGTGCAGGCACATTTTGCATCCTGGA
+AGAGTTCAAATTACGGCTTCTAGGTCATGGTGGCCGTGGCCGAGGCTTGA
+AGGGATGCTAGGTCAAGTCTGACGTCACATGTGGTTTTTCTAGGACACGT
+TACAAAGATTTCGAAGCGCCCAATTTTCGGAGAGGTTTCTAGGCCATGAA
+AATGTTCTAAATTTCAGGTTTCTAGGCCAGTAGAGAATTTTGAGGTTTCT
+AGGCCAGTAGAGAATTTTAGGCCATATCTGACGTCACACTTTTTGGGACG
+CGCCTAATAACGATGGTGGACCTCTATTCTAGGAGGAGCAACACATTTTT
+TACGAATTTCTAGAAGATGCAACTTCTGCTACTAGGCCACTCATGTGGTG
+CGAGGCTGTCCCATTACGGTTTGATCTACAAAAATGCGGGAACTTTTTGC
+CCAAAAAAATGTGACGCCGGCACGTTCTTAAACTTGCAAAATCAGTTGAA
+AACTCTGCGTCTCTTCTCCCGCATTTTTTGTAGATACGTAGATCAAACCA
+AAATGGGACCACACACACACACAAAACCCACTCTGACACTTGTGCGCCTG
+TGAGATGAAGTTCGTCAGGTGCCGATTGCAAAGAGCACATATCTCCTGCC
+GATGAAGTCGTGACATCTTGAATTGATGGTCTTTTGCGACGAACACGTCC
+GGCGTCAGTTCACTGGCAAAACTTGGTCCCGGAGACGGTTCATCCTCGTC
+CTCGTTCCTGCCAAAAAGTGCCTTCAAATTCTTTTTTGCCTTCTGGAATC
+CCAACTTTCCAGCGCCTCCTTTCTTTTTGGAATGTGTTGGGCTTAGCTGA
+AAATTCAAAAGTTTTTAATATTATAAGTAGAACCCTTACCGTGAACGAGT
+CATCACATCTTGACATTGAGAAATTGTTGGATTCGGTACTATTAGCCCTC
+CGTAACATTTTTAATTTGGTGGTTGAAGCCGTAGGGGCCAGAGATTGCCG
+TCTATGATGGGATAGATCAGCTCCTTCAATGAGCTTCAACTTTGTGTCTT
+CCAGGATAAATGTGGCGTCCACGTCGACGGCGTCATCGCTGAAAAAAGGT
+TTGCGTGTTACGGTAAGCGAGAATTATGGCAGAGGTGGGCGGAAATTGCC
+GTTCGGGAAATTTTTTGTCGAAAAATTGCCGGTTTGCCGAAAATTTGAAT
+TCCGACACTTTGTCGGTTTGCCAGAAATTTTCAATTCCGGCAATCTGCCG
+ATTTGCCGGAAAATTTCAATTTCAGCAAGTTGTCGATTTACCGGAAATTT
+AAATTCCGACAATTTGCCAATTTGCCGGAAATTTCAATTCAGGCCATTTG
+CCGATTTGTCGGAAATTTCAATTCCGGCAATTTGCCGATTTTCCGGAAAT
+TTCATATCCGGCAATTTGCCGATTTGCTTGGAAAATATCAATTCCGGCAA
+TTTGCGAATTTTCCAGAAAATTTCAATTCCGGCAATTTGCAGATTTGCCT
+GGAAATTTTCAATTCCGGCAATTTGCCGATTTACCGAAAATTTCAATTCG
+GCAATTTGTGAATTTTCCAGAAAATTTCAATTCCGGCAATTTGCCGATTT
+GCCTGGAAAATTTCAATTCCGGCAATTTACCGATTTACCGAAAATTTCAA
+TTCGGCAATTTGCGAATTTTCCAGAAAATTTCAATTCCGGCAATTTGCAG
+ATTTGCCTGGAAATTTTCAATTCCGGCAATTTGCCGATTTACCGAAAATT
+TCAATTCGGCAATTTGTGAATTTTCCAGAAAATTTCAATTCCGGCAATTT
+GCCGATTTGCCTGGAAAATTTCAATTCCGGCAATTTGCCGATTTACCGGA
+AATCTCAATCCGGCAATTTGCGAATTTTCCAGAAAATTTCAATTCCGGCA
+ATTTGCCGATTTACAGGAAATTTCAATTAAGGCAATTTGCCGCTTTACCG
+GAAATTTCAATCCGGCAATTTGTGAATTTTCCAGAAAATTTCAATTCCGG
+CAATTTGCCGATTTGCCTGGAAAATTTCAATTCCGGCAATTTGCCGATTT
+GCCTGGAAAATTTAAATTCCGGCAATTTGCCGATTTGCCGAAAAATTGCA
+ATTCTGGTACATTGCCGATTTCCCAGAAAATTTCAATTCCGGCAATTTGC
+CGCTTTACCGGAAATTTAAATTCCAACAATTCTGGCACATTGCCGATTTG
+CCAGAAAATTTCAATTCTGGCAATTTGCCGCTTTACCGGAAATTTAAATT
+CCGGCCATTTGCCGATTTGCCAGAAAATTTCAATTCTGGCAATTTGCCGC
+TTTACCGGAAATTTAAATTTCGGCAATTTGCCGATTTGCCGAAAATTTAA
+ATTCCTAAGAAACAGTGGCCGAGATCAGTTTTGACGTCACTTCTCTTCCA
+GAAAATGCACTAAAGTGATGTGACGTCATGACTGAGTTTCTAGGCCACGT
+TTCGTTTGATAAAATTGGCGGAGGACCTAATTTCCAATGGAAAATAAATT
+CAATTTTTTTAAATTTCATAATTTTCTGAAAAACTCACTCCTGAAAAGCA
+TCACTCTCTTCCGAAATATCATCATCAAGCCCATCCTGCGTAGACTTATC
+ACTATCCGAATCATCATCCGAAAGAGCAAAAGCCGCCAGAGAGCTCGGAT
+CACTCAAGTCGAACTTTGTAAGATTCACAGCATGAACCTTCCGAACTCTA
+AACGGTGACTTCTTAACGTTCAAGGCTCCATTGCCCTTTGGAATCTCGCC
+GACTCGCTTGCGAACCGATGCTCCGCGATACGCAGACTGCAGAGCTATCA
+CCGATTCTCTTATCGATAAATATTTCTGTCGTTGCTTGTACTTCTTCCAA
+TTACACTGTATCGTTTGAGCTGCTAAGGCTTTTTTCCGAACTTCGGCTCT
+TGCAAATGATCCTCGAATCAATGCTTGGATCTTGATAATACCCTCTTTCA
+TTCTCAAATATCGCTTTCTAGCCAACATTGTCCTGAACCATCGTTGAAGT
+GTATCGATTGATTGCATAATTGTCCGATGCAAATGATCATCGAGTATCAA
+CTTTTCAGCGTCTCTCATAAAAATCTTATTGGTTCCATATTGAATATTAT
+CATTATCAATCGATGCATGGGAATGTATGTACTCTTTCACATCGTCCACA
+GTACTATCCCTTCCGTTTCGCAAAAGAATTCGGTATTGCTGGACAAAGCT
+TGGATACTCAATTCTCACAGAGTACCCGGCTCTCCGAATTCGAACGGTCT
+CGAGCATTCCGGTGTAGCGGAGCTGGCGGAGGATTATGTTGTCGTCGAAG
+TGGTTGGCGATCTATAAAATTTTAGGTGAGTGGTTTTTGTCAATAATTTC
+TACTTATATTCAGTCATATAAATAAAAACACATATAAGAAAAGTACCAAA
+AATTTCGATCACCTAATTTTTTTAATTTTTTCTATACTCTTACTAGTATG
+AAAGAGCAGGATACAAAAATAACTCCACAAGTGATAAACCACCTTTAATT
+GGATTAGTGTGTATCACTTTGAGTAAGCTAATATTGAAGGTTTAAATGTG
+GACTACCTAGCCTAGCAAGAGAGGTCCTGTAAGTAGACTTCAAAAATATA
+GATTATCTTATGAACATATGAACTTATAAACAAACGTTGGTCAAAAAGTA
+GGTGTTCAAAGATTCCACCAAAGTTTACAAACTCACCTTATCATTATTAC
+TCTTAATACACCTTATAAAATACGGCGTCGCGTTGGCCAGTGTGCTCATC
+AACCTCGTCAACGAGTACTCGAACTGCTTTGAAACCGACGATGGCTTCTT
+GGCAAGCCTCCGTCCTCCGATAGCCTCCTTCAGAATTTGCAGCGATTTCA
+GCAAGCTCATTTTGTCGTCAGACTTTCCCGCCGGGGTACGCCGTGCTTGA
+TTTCTAATCGTGTTGAACATGCTGGTATCACAAAAGTCTGGAACTTCACA
+GCGAAGTTCGCCACGTAGAAATGCGGAGAGAGCAGAGTCCGAGCCACGAC
+GGGGAGACGTTACGATGGAGTCCATTACTCGGAGATGGCCGGCGGATTCT
+GGAAATGTTGAATAATTATATTAAGGGCAGGATAGCTCAGTCGGTAGTGG
+TGGCCGCTAGCAATCTGGAGGTCACGAGTTCAAGTCCGCCTTCAACCCCT
+AGGTTCACCAAGCCTCTATTGGAAAATGGAGCAATCCACGACTGGATTAT
+AAGCCACAGCCTTCGGCTAGGACGTGGCTTAAATTGTAGCCCAGTGGGAG
+CACCACCAGGTAGTGTACCTGACTCCCAGATCCGCAGATACACTCAAAAT
+AAAAAAACTGCGTGGCGTGTACTGCAGAAAACCTAATATTTAGGCCCCGC
+CTTTTTCTCGTCCACTCACGGAGAAAAGGCAACAATTTTGAACCCAACCA
+ATATCAGGCCGCCGACATCTCACGGGTTCCGCGCGCCGCTGCGTTTAACT
+CGCTGTGGGCGTGGCGAGCTGTCTCCGCTTGCTGCGAGTTAAACATTGCG
+GCGCGCGGAACCCGTGAGATGTCGGCGGCCTGATATTGGTTGTGGTCAAA
+ATTTTTTGCCTTTTTTCCGTGAGTGGACGAGAAAAAGGCGGTGCCTAAAT
+ATTAGGTTTTCTGCAGTACACGCCACGCAGTTTTATTATTTTGAGTGTAC
+TTGAAGAACGGATCGTCCTTTAATCCTTTAATTATACATTGCATTTTTTT
+TCCACTTCTACGACTTCGAAGGGGCGCATTTACGCGCGATGGTCCCGCCA
+CCCACCCCAAAAATCAATGGGTGGCGCGTGCCGAGACCATCGCTCGTAAA
+TGCGCCCTCCTTTAAAGTCGTAGAAGTGGAAAAAATGCACTGTAGAAATG
+AAGAATACCATACTTTTTGTGTTAATTTTTTCTATAATATCGTAGTTGTC
+CATTTATTTAAATCTTCCCACTTATTTAACTAAGGACTTCTAACGCTTAT
+TCCAGTTATTGGTTCCGATTAAATCTACGAAAACTTGCCACTTTTCTGCA
+GTTTCCTTGTCGATTGCTTGAACGCGTTCATCGCCCGAAACACACTTCTC
+AGCACATTCCACCTGTGCACCGCCACCGGATCGATTCCCAGCAGGGTCTT
+CATCACTGAGCTCGTACTGGACTTCAGAGCGTTCAACACATCCTGTCTCA
+TTAGGTCCTTATTCTTTTCTCGGAAACCCTGAAATTTAGTTTTGACGTGA
+TGATGGAAGACGTTTTTTTTGGAAGTTGTGTGTTTACCGTAATTTGATAC
+TTGACTTTTCCAGCATAATGAGCCACGATGAATGCCGGCTCCTTCTTCTG
+TGGGGTCTCATAGTATTCGTTGTTCTGGAAATTTAATCATGGAACTAGTC
+ATGTAAAAACATTTGAAGGAGTTAAGGTATGTCCCGGAGGAGTGAACATC
+TTAAGCCTGACCTAGAAGTTGATCCAAGTGGCAAGCCGACTGGCCTGAAT
+CCTATTAACAGGCCTACATGTGAATATTAAAGGTGGATTAGCGCCAGTGG
+GAATTTTGTCTAAATACACTTATAACGATGCCAAACGATCGAATATCATA
+ATAAAACACTCCAAAAACTTTTAGATTTTTCATAATTTCCGGTCAAAGTT
+TTGGAACATTGACAAAATTTTGACAAATTTGAGCTTTTGAGGACATCAAA
+ATCAATGTAACATTTTTTTGGACCCCTACAATGTCTTTTTACGAAAAATT
+AAAACAAAATTATAGTATAACAAATAGAGAAAAAAATTTTTTTTAGTCGA
+ATTTGTGTCACTTTTTGACTGTAAATAAAAAAATTTTGAAAAATTTTTGA
+AAAGTTTTATCATGAGATTTGGTCATTTTGGGAGCATAGGAGTGGTTTTT
+AACAATTTCCACCACCGGCGCTACTCCACCTTTAATCGATAATCGATTGC
+AATTTTTTCATACCTTCAAAAACTGATTTAACTTCGCCAGCATTGAGTCA
+TCTGTTCCATTATTGATATTACTCTCCTCATCGACTAGCCTGAGAATTCC
+ATATGGTTTACTCTGAAAATTCATCGGAATTTATATATATGGATATATAT
+ATATATATATATATATATATATATATATATGTATATATATACATGTATAT
+ATATATATATATACAGTGTGGGAAAGTTCTATAGGACCCCCCCTAATTTG
+AAGGTTTGAGGAACTTCCGAAAATTTTTTTGAAAAACTGCTAATGCCATT
+CGTTTTTAAATTGAAAAAAACCTATATACATTTTTTTCCAGAAGTTTATC
+TCAAAAACTGAGGTCGCGCTGGAAAAAACGTCAAAATCCAGTGTGAAACT
+TCTATAGGACCCCCCGTTTTTTTTCACGATTTTTACTAAAATCAACAGAT
+TTTGGAATTTTTGACAAAGCTCAAATCAAGTTTGAGTTAGAAATGAGTTC
+AGATAAGCAGTTTTGACTTTAAAAAATTAATACGAAATGTTCTCGTGGGA
+TCTCCAGACTGGTTCTGATTCTTCCGAACTTTGATGTTCAAGTCTGTTTC
+AAGCTTCCTGGTGCTCTCGGTAATGCCAAAACTTGATAAACTCTCTTTAA
+CAAGTTCCTACTAAAATTCCTAGCACACACACCATAAAAATTTTTACGCC
+ATCCCCAAGAAACCAGTCAGAAACAGCGTATTAACAAGTTGCAGTTATTT
+TTGATCAACAACAGAACATTCATATACTAAAATCAAGAAAGGATCAATAG
+TTAATCGGGTTTCCTTGTGTGCGGATGATCTCAAACAGTCTGTCCTCCAT
+TGATCTGACCAAACTTTTCAGCTGGTTGTCCGGAATAGACTTCCAAGCGT
+CGAGAATTCCTTGCTTCAACGATGCAACTGTTGGGTAAGTCTTGTTCTGA
+GCATACACGATACGGACAAGAATCCCCCACAAATTTTCGATTGGATTGAG
+ATCAGGACTTCGAGCTGGCCAATCAAGAAGGTTGATCTTCTTGAGCTTGA
+AATAGTCGCGGGTTGAGTTGCTCACATGGATTGTCGCATTATCCTGCTGA
+AATCTAAAGTCTTTTCTGGAGTAGTGACGAAGATATTTGGAGAGCTCCAG
+TTCCAAGACGTTCTGATAGTCAGTGCTGTTCATCTTGCTACTGACGAACT
+GTATCTCAAGCTTCTTCTTCTCCGTGAACGCTCCCCAAACCATCACCGTT
+CCTCCTCCAAAATTACGTCTCGAAAAAACCATTGGTTCCTTGCGCAAATC
+GCGCCAATAGTAGCGGCAACCGTCAGGCCCATCGAGATTGAATTTCTTTT
+CATCGGAGAAGACAACCTAAAACAATGATCCTAATTATTCACTCTTGCTT
+TTTTAAATTCTCACTTTACTCCAATTCGTTCCCATATTGTTCTTAGCAAA
+TTCCAATCGCTTGAGTTTATGGTCTGCAGAGAGTAACGGAGCAGGGCGAA
+GTTTCTGACGAACGATTACACCAGATCGTTTGATGACATTGAGGATGGTC
+CTTTTTGAAGCAGACAATTGAAGCTCATTGCGAATATCTCTTGCCGTCTT
+ACAGGAGTTGGAGGCAGCACGAATCACATTTCGTTCGTCACGCACGGAGA
+GAGCTTTGCGACGAGGAGCTCTTTTAGATGTACCGTAGCTCACCGGATCC
+TTCAGATACTCGCGAATACAGTGTCGAGAACGGGAAATTTTCCTACTCAT
+TTCATGCAGGGACACATTGAGCAATTTCATAACATCCAGCTGAGCGCGTT
+CAGTGTCCGAAAGGGCAGATCCTCGAGGCATTGCAAGTTAGACTGCTTTC
+GAAGTAAGCTTTCCAGCCTCTATATGTGTGCCACAACACATGCCACAATT
+CCACATTTAATAATTCACGCAAAAAATAGTAAATAACATCTGTGAGGGAC
+AATTTAACTTGAAATATTGGTCCCATGGAACCTTGTAATCAAAGAAAAAC
+GATTTGATTCCTGATAAGCCTTCCATTGTTTCCTGCTGCATATTTTGCCA
+AATCAGCTTGACTACACAGTCGAAACATCTAAAGTGCGTGCTAGGAATTT
+TAGTAGGAACTTGTTAAAGAGAGTTTATCAAGTTTTGGCATTACCGAGAG
+CACCAGGAAGCTTGAAACAGACTTGAACATCAAAGATCGGAAGAATCAGA
+ACCAGTCTGGAGATCCCACGAGAACATTTCGTATTAATTTTTTAAAGTCA
+AAACTGCTTATCTGAACTCATTTCTAACTCAAACTTGATTTGAGCTTTGT
+CAAAAATTCCAAAATCTGTTGATTTTAGTAAAAATCGTGAAAAAAAACGG
+GGGGTCCTATAGAAGTTTCACACTGGATTTTGACGTTTTTTCCAGCGCGA
+CCTCAGTTTTTGAGATAAACTTCTGGAAAAAAATGTATATAGGTTTTTTT
+CAATTTAAAAACGAATGGCATTAGCAGTTTTTCAAAAAAATTTTCGGAAG
+TTCCTCAAACCTTCAAATTAGGGGGGGTCCTATAGAACTTTCCCACACTG
+TATATATATATATATATATATATATATATATATATATACATTTGAAACCC
+AAAAAGGACTTATTGGACTTACCTGAAACAGCTGCACACACTCCGTATTA
+TCAGTATACTCGATATTGGTCCAAGAAATGCCCTCCTTCAAGTACTCCTC
+TTGTTCAAATTGGAAAATATGTTGATTGAAATAGGACTGAAGTTTCTCAT
+TGGCATAGTTGATACATAACTGTTCAAAGCTGTTGCATTGAGACCCAACG
+TCTTCAAATCCGAATATATCCAAGATACCTGAAAATTACTTCAATTTTTA
+ACAATTGATAATTAATCTAACCTATATAATATCCCTTCCCAGCTGAGAAG
+TCCTTCTTCAGCAATGCCTGATTAATCCTGAGGACTATATAGTGAAACAA
+AGAGTTGTATATGCACTTTGCCATGGCATCTCGGGTGTTGGTGGCCTGAA
+ATTAATTTTTTTATCTTAAATTCTTAATTTCACTTCTGTATATATATATA
+TATTACCTCAGAGACACTATATCGCAAAACTACAGTTTCTGTCTTCATAA
+CATGTCGTTTCATAGTGAGAGCCTGCATGAGAGTGTCGGTTTTGATGTGA
+AGCAGATTTGCGACTAAATCCACGACTTCTTCATTTTCAATATACCCACT
+TTCATCGCTATGGTAGCCATGTCTCTGGAAAATTATAGGAAAAATAAAAA
+AAATTTGATGATGTTATTATATTAGGAATCCTCTAAACAAGGGTTTTCAG
+GTTTTTTGGTTTTACGATTATTCAAATTTTTATGGAAATTATTATAATTC
+AAATAATTTTCGTCACTATTATAGCCATGTTGTTGAAATAATATGCTATT
+TTTAAAGGTGGAGCACCGAAATCTGGAAACTATTTTTAAATGAGTCCAAA
+TTTTCCCCTGATTCCGAATATCTATGCGAAAAAATTTTAAAAAATTCATT
+TATCAAATTTTTCAAATTTTTCAAACGCCGAATTTTCGCGCCAGAAACGC
+CGTGTGCACGTGGTATCAGAGTGTCTCATTTTGGCTTGATCTACGCAGAT
+CTACAAAAAATGCGGGAGAAGAGACGCAGAGTTCTCAACTGAGTTCGCAT
+GGTTAAAAATGTGCTGACATCACATTTTTTTGGCATTTTTTGTAGATCAA
+ACCGTATTGGGAGAGCCTGGCACCACGTGAGTAGGCAGGCATTTTTTGCC
+TGACTGCTTGCGGGTGCCTCGTTTTTTCCTCAGAATTTTTTGGCGCGAAA
+TTCAAATTTTCAAATAATTTTGAATATTTTCGAGTGAAGCTTTAAAAAAT
+TGTTTGTGCCAAATTTGAGTTTGCAAATAAATTATCAAAAAATGTGCTGA
+CGTCACGTTTTTGAGCAAAAAAATCCCGCATTGTTTGTAGATCAAACCGT
+AATAGGACAGCCTGGCACCACGTGCGTGTGTCGATTTACGAGATTTGTGT
+ATATTTACGAAATTTTTTATCTTTATCAGACTCTGATTTCCGTTTCTCAA
+CGAGTTTTCTTCATTTTTGTATGTGATTTTTTTAAGGTCCATTAAATATT
+TTATCATCAAAACCCTAGCAAAATTTTTGGTTTTCAGTCGGTAAAATCAT
+ATAGGTAATTGGATTTTCCGTCAAGTTGTGACCTAATAGTAAGCATTGGA
+AATTTTGCCAGTTTTAAATAATTAATTGACCCTAAAACACACATTTCAAA
+AAAAAACCGATAAAAATTAAAAATTCCGTAAATATACACAAATCTCGTAA
+ATCGACACATGGCTCTAGCGCGAAAATTCAAAAACTCTTGGGTGTACAAA
+TAGCGATTTCAAGCTCAAATATAAAATCGTGGAAATTTTTTAAAAATTTT
+TTTCACATAGGTATTCGGAGTCAGGGGAAATTTGGAGTCAATTAAAAATA
+TTTTCCGGATTTCGGTGCTCCGTAGAACTCTCTGAATAAAATTTTAAAAC
+TATGGCAATAGGCAATTATTCGGTAGTTAACTTCTGAGTTGTATTTCTTT
+TTGAATCTAAACCGTCCCAATCATTTACCTTGATATATGTGATATTGCCA
+AGAAGCAACACTGCCGAAATAATCCCGAAGATGGTCTGCTGGGTCTTTGC
+ACAAAATCCGACGGAGCTCATTGCATGCCTCAACCTATCAAACTCATTCC
+GCTCGTTCACACCTTCCAGTGCAAATGGCTCGTTCTGGAAATTTTTAATT
+TTTTTTTAATTTTTTAAAAAATCGCTTTGAGGTCAGCGAATGTATCCCAT
+ATTCGCTCCAAACTTTTCCCAGCTCACCTGATTCAAATACTTATAATCAT
+GTGGCTTCAACAAGAAATATTTCTTCCTTTCTTCCTCGTCTGCACCCTCC
+AGAAGGTAGTAGAATACGTGGTAGTTTCTGAAAAAAATATTAAAGTCCAA
+GTGAGACACCAAGGGAGTTTATGTACCGTTCTCCTTTAGTTTGAAATATG
+ATGCGTGATTTTTCCAGCAGGTAGATCTCCACGTTTGCTCTGAAAAGTAC
+AAGTATAAGGCATTTTTTGTGGTATAGACATCAGGAGAAGGCTTCAAATT
+TTACGTTCAGGTCAATTTAGGTCATAGTGCCTAGTAAGTATGGTACCTAT
+AAGCTTGATTACTGCCAAAGTAAAAATTTTCCAATTCCGGCAATTTGCCG
+ATTTGCCAGGCATTCCAATTCCGGCAATTTGCCGATTTGCCAGGCATTCC
+AATTCCGGCAATTTGCCGGTTTGCCGGATTGCCGGAAATTTAAATTCCGG
+CAATTTGCCAAATTTTTTTTCATTTTCGGCAATATACTGGATTGCCAAAA
+TGTTACGGCAACTTGCCAATTTGCAGGAACTTTTCATTTTCGGCAAATTG
+CCGGTTTGCCGATATCCCAGAAATTTTCAGGTCCGGCAAGTTGTTGATTT
+GCCGATTTTCCCCGGAAATTTCAGTTCCGGCAACTTGCCGATTTGCCGGA
+AATTTTCAAATCCGGCAATCGCGGGAAATTTCAATTCCGTCAAATTACCA
+ACATGCCGGATATTCCAATTCCGGCAATTTGCCAATTTGCCGAGCATTTA
+AATTCCGGCAATTTGCCGAATTGCTGAAAATATCAATTCTGTCAAATTGG
+CAATTCGCCGGACATTCCATATCCGACAATTTGCCGATTTGCCGATTTCC
+CAGAAGTTTTCAATTCCGTCAAATTTCTAATTTGCCGGAAATTTCAATTT
+TACTAAGTCGCCTGCTAGCCTCCTAATCTCACCCGGAAACCATTCCATTC
+TCCCGATAGTTGATTTTGATGAATTTTCCAAATCTGCTACTATTATTGTT
+CGTTAATGTGACAGCATTTCCAAAAGCCTCTAGAACAGGACCAGCTGACA
+GAAGTGTCTGCTCAGTACTGCAGCCTGTTGAACCTTTCTGTGATAGCGAT
+ATCAAATGGGACATCAGATGATTCGTGGATTCCGTTTTTCCCGAACCACT
+TTCCCCGGAGATTACCACGCATTGATTTTCCTTGATACGGAGCATGCTGA
+AAAAATTGTTTTTTTAAAAATTAGTAGTGACATTTAGTTAATCCAGCATC
+AGAATGTATATCTCTGAAATTTTTTTTTTTTGAAATCAAAAGTGCTTTGA
+GGGTCTTGAAACGAACACATAACTGCAAAAAAATTGGTGGCCGAGTTTAT
+AATCGGCCACTTGGCAAATATACAAGCCAATACACAAAGTGAGCACCTAC
+GTGGCCGAGTGAAGAGAAAACTCGGCCACCGATTTTTTTTGGTCACTTGA
+AATTTCAAAAAATAGTAACTGGGTTCCGGTAAGAACTTAGAACTCACTTG
+TGGTAACAGACATCGGCGATTGCAAAAATGTGCGGTGGTAGTGAGCCGAG
+CCGCTTACTTTGAAAGTATAGCCTAGCATATTTTGGGTTGTAGATCGGAA
+AAAAGCAAAACGGGTTCACGGCTACTAGAATTGGACCGATGTACGTGTAA
+ATGTGCCCATTCGCGAATCTTTCCCGCAAATTGTCCAAGAGGGTTTGCTC
+CGTGAGCTCTGGCAAGTTACAGAGATCGGCGTACTCGCGGTCCTGAAAAA
+TTTTAAGGTTTAAAATTTTTTTAAATATAAAAATATTTAAAGGTGGAGTA
+CAGGAAATCTTTTTTAATTACTCCAAATTTTCCACTGATTCCGAATATCT
+AAGTAAAAAATTTTGAAAAAATTTCCCTGATTTTGTATTTAAGCTTGAAA
+TTACGATTTTCATTTGTGCCCGCACCACTTTTTTCAAATACGCCCAAAGA
+AATTCGCATTGGAGCGCGTTTGCATCGTTTGATTTTCGTCGTTTATTTTA
+TTTATTTTCCACGGGGTTCTGGCCTTCTTCATTGAATTTTCGCGCTTCAT
+TGACAATCGCCTGCCGGACAACACATGGAAAAGTGTCGTGTACTCCACAC
+GGACAAATACATCAGTTTTACAACTAAAGACAAGCCGCGACGCGACACGC
+AATGCGCCGTAAGTCTACACAAAATCTCTCCGACCCAAAATGGCCTAGTT
+CGGCAAACTCTGCCATTTCGATTTATGAGGGAAGCCAGAATTTCGTGATT
+TTCGCCGAATTCAATTTTCTTGAACCAGTTTCAATCATTTTTGTCGAGTT
+TTTGCTAGTTTTTTTTTTGACAAAAAGGAATGAAACTGGTTAAAAAAACT
+GAATTTGGCAAAAAATAAATAAAATCTTTAAATGAAGGAAATCAAAGCGC
+GCTCCAATGCGAATTTATTTGGGTGCGCATTTGACAAAAACACGTGGTGT
+CAGGCAAGGGTGTCAATGTCCCGTAAAAATTTCGAAAACGGGACAACGGG
+AATTCCCGTTCCCGTGAAAATTTTAAAAACGGGAAAACGGGAATTCCCGT
+TCCCGTGAAAACTTCAAAAACGGGACAACGGGAATTCCCGTTTTTTTGAA
+AACACTCAAAAAACGGGACAAACTGGGCGGTTTAAAAAAAAGAGTGCATA
+GTTGGCGTAAATTTTAGTGTATTCGAGGCAAATTATAAAAAAAAACTGCA
+TTATAAACATTTTTATCGATTTTTTCAATATTAAACAGATATTTAAAAAG
+CCAAAAAATGAGGGAAAATGTCCCGTTCCCGTGAAAATTTTAAAAACGGG
+ACAACGGGAATTCCCGTTCCCGTGAAAACACCCCAAAAACGGGACAACGG
+GAAAAACGGGAAACGGGAATTGACACCCTTGGTGTCAGGCTGTCTTATTT
+CATTTTTATCTACAAAAACAGCGGGAATAGTTTTCCAGAAAAATTCTAAC
+GTCTCTTAACCAGGCGAAATAAAATGAGAAGTCTGCGTCTCTTCACCCGC
+ATTTTTTGAAAATCAAAAAAAGAGACCGGGCACAAATTAAAATCAGGGAA
+AATTTTTTTAATTTTTTCACATCTAAATTCGTAATCGGGGGGCAAATTTG
+GAGTGATTTAAAAATATTTCCCAGATTTCGGTACCCCACCTCAAAAAAAA
+ATAATTAAAGAATTGCCTTACCTGTGGCTGAACCAAGAATTTCGTAAGAA
+AAGCGTCAATCGATGAGGCGACCTCTGCACTTCCAAACCGAGTGCCGCCG
+GTTGCCGCCCGATAACCGCGGTGTCGAAAAACAAATCGATTTTTTGGAGT
+GGCACTGTCCACCACTACAGGCAGTCTTGACCAGATGGCCTGTACCGCGA
+CTGGGTATTCCCCGGGGTCTAGGCGGCGTTCTTTATAGGTTTGACCGTCG
+GGGGTGCCCATCATTTCGAAGAGGTCAAAGTCTTGTACCGACTGGCCTTC
+TAGTTCTGGAAATTTTGACTTTAGAAAAGAAATCATTTTTTTCCTTTTTT
+TTTTAAATTAGCCCGTGGCTTTTTTCAAAATTAAAAGAAAATTTGAAAAA
+ACATTGCATTAGAGCGCGTTTGCATTCACTCCATGCAGTCCAATTTTGCT
+GGGAGCTTGAGTGTCTCATTCGACTTGATCTACACAGATCTACTAAAAAT
+GCGGGAGAATAAAATCCACTGATATTGTATGTTTAAGAATGTGCTGACGT
+CACATATTTTTGTGCAAAAAATTCCCGCATTTTTTGTAGATCAAACCATG
+ATGGGACAGCCTGGCACCACGTGAGATTGTGTCGACAAATTTTTGTTGAA
+GATGTATGGCCAAAAACGGCACATTTAAGTAATTTATCAGTAGAGCGCGT
+TTGAAATTTTTTTAAAAATTCTTTTTAAAAAGAGTTCCCACTACCCCAAG
+TCCTCCGATTTTTCTAAAAACTAAGAGAAGGGAATCTACGACCCTGAGCC
+TTTAAAACCTTACCAGCTCTCCCGGCGAGCACTTTTTCGATGAGCTCCTC
+CGTCGTGCACCGCTTATGAACCTCCAAGTGTACCGTATCATTTTCACAGT
+CGGGATTGAAGCTGTGCATATAGACGGCTACCGTATGTGTGTGTGCATCG
+TCTGTCGCGTTGATTGTGTGAGCACGTCGGGGAAAACATCCCGTCGCTCC
+AGCTGATATTGAGTCAAATGACATTTAGTTAATCCAGCATCGGGATGTAT
+ACGTCTGTAAAAAAAAATTTTTTTTGAAAGTAAAAGTGCCTGGAGGATCA
+TGCAACGAACACAAAAATTTCACAAGACCGCGAAAAAAATTGGTGGCCGA
+GTTTTCTCTTTCGCGGTCACTTAGGAAATACTAAAATCGCACGGATTTCT
+GGCTTCTCTCATAAATTGAAATGGAAGAGTTTGCCGAACTAGGCCAGTAT
+AGCTCGGCCATATCTGGGGTATGTTTACGACTTTCCCACGCGTTGGGCGA
+TTGTCAATGGAGCGCGAAAAACTCAATGAGAAAGGCCTGAACCCCGTGAG
+ATCGAAATGAAAATTTGCTAAATGGCCGAAAATTGAAAACTCGGCCGCCA
+ATTTTTCCACACGGCCACAGGAAAAATCGTAACAAAAATTGAGAGAAATT
+TATTAGAAAAAATCTGAAAGTAATTTTTATTGCACCGTGGCCGCAAAATG
+TAAAAACACGGCCACCGATTTTTTTAATGTGGGGAAAAAGTTGGTGGCCG
+AGTTTTATATTTTGCGGCCACTTAGAAAATATTTAGATCGAAGGGAAATT
+TTGTTGAAAATACGTTTAACGAAAACCAGTCAATTTTTGTTACATGACCG
+AAAATTGAAAACTCGACCACGGATTTGTTATGCTTTATAAATTTTTGAAA
+CTATTATTTTTTGATTCAGAAATTTTTGGAATTGAAAAAAACTCGGCCAC
+ATTTTTTTTCTCACGGTCACAATTTTCTTTGTGATCGTAAAAATGGAAGC
+TCGGCCATGGTGGCCGAGTTTTTTTCGCTGCCACTGGTAACACGTGGTTG
+GGTGAAGAGAAAACTCGACCACCGGTTTTTTTTGGCCACTGAAATTTTTA
+AATTTCAAAATATTTTAAATTTTGCTGCAATCTTTCACCACAACCGCGAA
+AAAATGAAAACTCGGCCACCAATTTATTTATTTTCACTGGGAGAAAAAAT
+ATTGTTAGCCAAGTTTTCTTTTAGGCAACAGAAAATCAAAAAATGAGCGA
+TTTTTGTTACGTGGCCGTGAAAAGAGAAAACTCGGCCACCAATTATTTTT
+AATTTGAGGCACTGTTGTAAAATCTTATAAAAAAACAGGTTTAGTACATT
+GAACTCAAAAATAAGGAAGATTTTTGGAAAAACAAAAATTGCTGGCCGAC
+AGCTGGAAAAAACTCGGCCACCAACTTTTTCCGGTCACACAGCAAAATCT
+CTCGATTTTCGATGTTTGAATATTGAAATCTGGGTTGGATTTTTTAGTAT
+CATTTCATTTCCGGTGGAGAAACGAGGGAGAGAAAAAGAGAAAAAAGATT
+TGTAGTGTCCCGGGAAGCTCTCTTTCTCATGTGGGAAGAAAGTGGAAGAA
+GCTTCTGCAGCAGCAGCAGCAGTGGTTCACGAAAGAGAGAGAGAGACATG
+TTGGACATGAAAATGATGAAAAATAAGAAGATGAAGAAGAGAATTACACA
+CTACCACCACAACACAGATTATTTTTATCACGTTTTGAGGGGGCGCTTCA
+CACAATTTTCATGGCCTAGAAATTTAAATTTGGTGGCCTAGAAAATACTA
+TATTAATTATATTAATTATTCTACGAAATTTCAATAATTTAAACGGGAAA
+ATTTATTTTAAAAAAGCCTAGAAGAGGTTTTGAAATTGGTGGACTAGGAA
+ATGAAAAATTGTGTTTTTGGAATTTTCTAGGCCATTTGAACTTCCTGACG
+TCCACAATTTTCATGACTTCGAAATTTGAATTTGGTGGCCTAGAAAATCA
+TAAAAACTAAGAAATCGAGAAAAAAGCATGGATGAAATTTTGAATTTTAT
+AGGTCATTTGAAATTTGTGGCCTAAAAAATGAAAAATGATTTTTTTTTTT
+TTGAATTTTCTAGGCCACTTGAATTTCCTGACGTCCACAATTTTCATAGC
+CTAGAAATTTAAATGTGGTGGCCTAGAAAATAATTAAAACTAAGAAATCG
+AGAAGAAAAGCGTGGAAGAAGTTTTGTATTTTCTAGGCCATTTGAATTTG
+GTGGCCTAGGAAATGAAAAAAAGATTTTTTAGGAAATTTCTAGGCCACTT
+GAAGTTGGTGGCCTAGGAAATTAAAATTTGTGTTTTTGGCATTTTCTAGG
+CCATTTGGATTAGGTGGCCTAGGAATTGAAAAGTAGTTGTTTTGGAATTT
+TCTAGGCCATTTGAATTTGGTGGCCTAGGAAATGAAAAAATATTTTTTAA
+AGGAAATTTCTAGGCCATTGAAGTAGATGGCTTAGGAAATAAAAAAAGGT
+TTTTTAAAGGAAATTTCTAGGCCATTGAATTAGGTGGCCTAGGAAATGAA
+AAATGATTTTCTTAAAATTTTTTAAGCCACTTGAATTTGACGGCCTAGGA
+AATGAAAAATGGTTTTTTGGTAATTTCTAGGCCACTTGAATTTGGTGACC
+TGGGAAATGAAAAATGATTTTCTTGGAATTTTTTAGGCCACTTGAATTTG
+ACGGCCTAGGAAATGAAAAATAGTTTTTTGGTAATTTCTAGGCCACTTGA
+ATTTGGTGGCCTGGGAAATGAAAAATGATTTTCTTGGAATTTTTTAGGCC
+ACTTGAATTTGACGGCCTAGGAAATGAAAAACAGTTGTTTTGGAATTTTT
+TAGGCCACTTGAATTTGACGGCCTAGGAAATGAAAAATAGTTTTTTGGTA
+ATTTCGAGGCCACTTGAATTTGGTGGCCTGGGAAATGAAAAATGATTTTC
+TTGGAATTTCTAGGCCATTGAATTAGGTGGCCTAGGAAATGAAAAATGAT
+TTTCTTAAAATTTTTTAAGCCACTTGAATTTGACGGCCTAGGAAATGAAA
+AATGGTTTTTTGGTAATTTCTAGGCCACTTGAATTTGGTGACCTGGGAAA
+TGAAAAATGATTTTCTTGGAATTTTTTAAGCCACTTGAATTTGACGGCCT
+AGGAAATGAAAAATAGTTTTTTGGTAATTTCGAGGCCACTTGAATTTGGT
+GGCCTGGGAAATGAAAAATGATTTTCTTGGAATTTTTTAGGCCACTTGAA
+TTTGACGGCCTAGGAAATGAAAAACAGTTGTTTTGGAATTTTTTAGGCCA
+CTTGAATTTGACGGCCTAGGAAATGAAAAATAGTTTTTTGGTAATTTCGA
+GGCCACTTGAATTTGGTGGCCTGGGAAATGAAAAATGATTTTCTTGGAAT
+TTTTTAGGCCACTTGAATTTGACGGCCTAGGAAATGAAAAATAGTTTTTT
+GGTAATTTCGAGGCCACTTGAATTTGGTGGCCTGGGAAATGAAAAATGAT
+TTTCTTGGAATTTTTTAGGCCACTTGAATTTGACGGCCTAGGAAATGAAA
+AATAGTTTTTTGGTAATTTCGAGGCCACTTGAATTTGGTGGCCTGGGAAA
+TGAAAAATGATTTTCTTGGAATTTTTTAGACCACTTGAATTTGACGGCCT
+AGGAAATGAAAAATAGTTTTTTGGTAATTTCTAGACCACTTGAATTTGAC
+GGCCTAGGAAATGAAAAATAGTTTTTTGGTAATTTCTAGGCCACTTGAAT
+TTGACGGCCTAGGAAATGAAAAATAGTTTTTTGGTAATTTCTAGGCCACT
+TGAATTTGGTGGCCTGGGAAATGAAAAATGATTTTCTTGGAATTTTTTAG
+GCCACTTGAATTTGACGGCCTAGGAAATGAAAAATAGTTGTTTTGGAATT
+TTTTAGGCCACTTGAATTTGGTGGCCTAGGAAATGAAAAATGATTTTCTT
+GGAATTTTCTAGGCCACTTCAATTTGGTGGTCTGGGAAATGAAAAATGAT
+TTTCTTGGAATTTTTTAGGCCGCTTGATTTAAGTGGCCTAAGAAGTTAAA
+AATAGTTGTTACGGAATTTTCTAGGACATTTGAACTTGGTGGCCAAGGAA
+ATGAAAAACTTTTTTTTTTGGAATTTTCTAGGTTTCTGTAATATTAATTT
+ATTCATTTAAAAAATTAAAAAACATTAAATTTTTTTTAAATTTCGTGTTT
+CAAAAAAAAAATCAAATTTGCCCAAAACTTCAAAAATAAGCTAAAAAATT
+GTAAAACGATACAGAACGGCTAATAAAACTTGAAAATAATAAGCGTGATG
+AGTCGGAAAGAGCCGCCGGCTGGGACCTTCTTTTTCTCTTTTTTTCTCCT
+CTCCCATCCCGAGCAGGAGCAACACAACGAGAGAGCACAACAAGAAGAAA
+AAGCAGATAGATATATAGATATATGTTGTCTTCTCTTCATATTCTTTCTT
+TTATCTTTTCATTCGAAACAACACTTGGTTCATTTCTCCCGTTGGACGGG
+GGGGGGGGGGGGGTGACGCGGGAGACGAAAAAAAAAAGAAAAATTGGGAT
+GGGAGTTGGAGAATGTTTGGAAAAAGATTGATTGATCAATCAATTTGCCA
+GCCGAGTCTCGGCTATTTTCGGAAATCGGGGCTATGCAAATGCGCCCTAC
+TGATAAAATGGGACGTGTCATTTAAACTCCTTGGTTTTTTAAAAAGAAAC
+GCAAAATCGGCAAATTTCCAGTTTGCCGATTTGCCAGAAATTTTCAGGTA
+CAGCAATTTTCCGATTTGCCGATTTGGCGGAAATTTCAATTTCGACAAAT
+TGCCGGCTTGCCGAAATGCCAAAAATGTCCAGGTCCGGCAATTTGCCAAT
+GTTGATTTTTGGCAAGTTGCTGGTTTGCCGGAAGTTTTCATTTTCGGCAA
+ATTACCGATTTGCCAAAACGCCAGAAATGCTCAGGTTCTCTAAACCGCTG
+GTTTTCCGGAAATTTTTCATTTTCGGCAAATTGCCGGCTTGCCAAAATGC
+CGGAATTTTTCAGGTCCGGCAATTTGCTGATTTGCCGGAATTTTTCATTT
+TCGACAAATAGCCGGTTTGCCGAAACGCAAGAAATGCTCAGGACCGGCAA
+TTTGCCGATTTGCCGGATATTTTCATTTTCGGCAAATTGCCGGTTTGCCG
+ATATGCCAGAAATGTTCAGGACCGGCAATTTGCCGAATCGCCGGAATTTT
+TTATTTTTGGCAAATTGCCGATTTGCCGAAAGGCCAGAAATGTTGCGGTC
+CGGCAATTTGCCGAAATGCCATAAATGTTCAATTTCGGCAATTTGCTGAT
+ATGCCGGAGTTATAAATTTCGGCAAATTGCCGGCTGGTCGATATGCCGGA
+AATTTTCAGGTCCTGCAATTTGATGATTTGCCGAAAAATTTATTTAAAAA
+AAAAATTAATTTTCGCCAGACAGGAAGTCTCTAAAATCTCATTTAATAAG
+AAGAAACAAAAGAAACAAATAATGGCCTAACAAGTTTCGAGTTACAGAAA
+CCTAGGCCACTTTGAACACCGGCGTGGCCTAGAAACCCAGTTCCACAAAA
+ATAAGAAAAAATTAAAACTCGGCCACATAATCTAGGCCAGGAGCATACAA
+ACACTCCACGAATATTAAAGACTCTTTCTAGGTTAGTGGCCGTTAACGAT
+GGAAAACTCGGCCATCTGCCAATTTTGTTGCTTAAAATTGGAAAAATAAA
+GTTTTTTTAACTTCAAAAAAAAAAGATCAAAAAGTGAAAAGCGGGGATTT
+TTCTCACACAATTTAATAAATCTGTAGCCGAGTAGCGGAGAGCTCTCGGA
+GCTCAACGTGAATTTCTATTTGGACGGTAAACATACTCAGCCACCCCACC
+CCAGCCCACCGTTACTGTCTTTTTTTTTCTTTTTTATTATCAACCAGCAC
+TTATCACCTTTATCTTTGTGTGATCCCGCGCCGCGCAAGAACGAGAGAGA
+GAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGA
+GAGAGAGAGAGAGAGAGAGAGAGAGAGGGATATTGGTGAGACGCAGACAA
+TTAGAGTCACTCGTGGGCTCTTTCACACATGTGATATTGAACGAGAAATT
+GCGCACCTAGGCCACAAAAAAAACAGTGTATTCGATTTCATGATAGGGGA
+GAAGCTGGCACGGTGCCAAGTTTCAGAAAAAATATGGAATTTTTGCTTGA
+AGCATGGTGAATCAGACGTGCTTACGTCACAATTTTTCGGGATAAATATT
+CCCGCATTTTTTGTAGATCAAACCGCAATGAGACATCCTGATACCACGTG
+AGGTTAATTAAAAGTATTGATCGGGATTTTGAGCGTCAAATATGGTGTAT
+TTACCGGCAACCCTGATGCGCCAGATTTGACGCGCAAATCCTTCATTTTA
+ATAAAGTTGGGCGTCAAATGTGATGCCTGAATTTTCAATTTTTTGAAATG
+TTTTGATTTCGTGAAAAATAACGGCGAATTTCAGAAAATTTATAGAAAAT
+TTTCATTTGTTGCGACCAAAAAATCTTAAAAACGACCAAAATTCTCAGGA
+AATTCACATTTTTCGCCGAAAAAACCATTTTGCGCGTAAATTCTGATGTA
+TTTTGCCGTAGGCTATGTGTGAAAACACTGCCGGTAATACGTCATATTTG
+ACGCGCAAACCACAAAAATCCTCGAAATTATTCCGGGTGCACAAAATTCT
+GAGAATGCGTACAGCGCAACATATCTGACGCGCAAAATATCTCGAAGTGA
+AAAATACAGTAATCCTTTTCAAATGACTACTGTAGCGCTTGTGTCGATTT
+ACGGGATCTCGACTTTCGAAATGGATTAAAATATATTATTTATCAATAGA
+ATATTACAAAAAGAAGTTAATTTCGTAAATCGAGCCCGTAAATCGACACA
+AGTGCTATAGTAGTAATTTTAAGAATTACTGTAGTTTTCGCTACGAGATA
+TTTTGCGCGTCAAATATGTTGTGCAGTACGCATTCCCAGAATTTTTCGTT
+CCCTTTCACAAAAATCTTCAAACTTGCGCGTAAAATTTGGTGCATTGGTG
+CCTGTGAGGGGTTCACCTATACAAGTGGTGCCAGGGGCTGTCCCATTACG
+GGTTGATCTACAAAAAATGCGGGATTTTTTTGCCCAAACCATGCGAAATC
+AGTTGAGAACTCTGCGTCTCTTCTCCCGCATATTTTGTAGATCAACGTAG
+ATCAAACACTCTGACACCACGTGGGCCGATGATGTAAGTGCACCAGATTA
+CACGCGCAAAAACTGAAAATCTGAAAAAAAAAAAAGCGAAAACTGTCAAA
+TTTGAGCGAGTTTTTTATTCCACGAATCACAAGAAAAATCAATAAAAAAT
+CGATAATTAAAAAGTGAGTATCATATTATTCGACAACAGAATTTCCAGTT
+TCATCAGTGAGCATTGTAAGTATACGATGAGCCATCGACGGTCCAACACG
+TCTCCCGTTCTCTGCCACAAGTTCGCCAATCTCTTGAATAGCGAGCGAGT
+AGTCCATTTTCGAGTATTTATCGATTGCGGCAATCGGATCAGGGATTAGT
+TCGAGAATTGCACGTCGCTGAGCATCCGACAGCCGATCGATTGTTGTGAG
+CATTTTCGACCACCAATCCGTGACGATTTCCGAGCGACTTCCGATCACAA
+TTCCCTGGAAAAAAATCATCGGGGTTTCATGCTTTTGATCTATTTGATCT
+ACAAAAAATGCGGGAATTTTTTGCCCAAAAATATGTGACATCGTCAGCAC
+GTTTTTAACCATGTGAAATCAGTTGAGAACTCTGCGTCTCTTCTCCCGCA
+TTTTTTGTAGATCTACGTAGATCAAGCCGAAATGAGACATTCTGAGTCTT
+GACACGACAAATTCCCGTTAATTACATACGGATGTGAGCCTTTGTTGGAT
+GTGAGAGAGTTTCCAGGTTTTTCTCGAAAGCTTTTCTTAAAATTTCATTT
+AAAAAATAATTTTTTAACGAAAAACTACAAAAAATCATCCGAAAAACCTG
+GAAAATCGATGAAAAACTCTGTGACAAATACAGTACTGTTTAAAGGCGCA
+CGCCAGTTTGTGTTCTGAGAATGCGTATTGCACAACATATTTGACGCGCA
+AAATATCTAAACTACAGTAATTCTTCAAATGACTACTGTAGCGCGCTAGT
+GTCGATTTACGGGTTCGGCTTTCGACAAATTTCGAAAATCGAGCTCGTAA
+ATCGACACAACCGCTACAGTAGTAATTTAAAGAATTACTGTAGTTTAGAT
+ATTTTGCGCGTCAAATTTGTTGTGCAGTACGCATTCTCAGAACTTTGCGT
+TTTCGTGATTTTTTTTTTCAAATTTTAACTGCAGTAAAAAAATAAAACAA
+CATAAATTTCATTTAAAAAAAACGATTTTAGCGCTCTTTAAAGGCGCACA
+CCCGTTTGTGTTTTAAAAAAAAAAAATGTCGCGTCGAGACCAGATTTCTG
+CAGATTTCGCGCCAAGACCCAACCTTATCCCCCTGATACTGTAATTTGTG
+GCCTCCTGCCCCTCCTGCACCACCACCACCGCCCCCATCACTTCCAGCGT
+CGAGCTTCTTCTTCTCCTGTCTCGCCAAACTTCTCAAGTACTGAGCAGTG
+AATAGTGCCAGCTCGGCGATCGTTTCGATTTGCACAATTTGTGCACGATG
+TTGCTCGTAGATTTGCAGCGATAAATTGTGCAATTTCTTCTTTTTCGCAA
+TTTCTGCCCTGCCGAATGAGACGATGAGCATTGTGCAGCGGCCACCGTTT
+TGAAATCCGGATTTTTGCTGGAAAAATAAAATTTAAATGAGATTTTTTTT
+AGGTCTCGCAGCGATTTCTCTGGCTGTTTCAATTACGGTTTGATCTACAA
+AAAATGCGGGAATTATAAAAAATGTTTGCCCGGTAAAATGTGACGTCAGC
+AAAGTTTCTTAACGCTGCGAAATCAGTTGAGAACTCTGCGTCTTTTCTCC
+CGCATTTTTTGTAGATCTACGTAGATCAAGCTGAAATGAGACACACTGTG
+TGTGCAAACACTATCCACAATACATCATATTTGACGCGCAAACTCTAATT
+TTTTTTTCGCTGCGAGACCTAAAAAATCTCAAACTTTCCAGTGAAAATCC
+GGATTTTCTTCATTTTAAAAAAGTTGCGCGTCAAATGTGATGTGCCTGAA
+TTTTCGCTTTTTTGAAATTTTTTATTTCGTTAAAAATGACGACGAATTTC
+TGAACATTTATAGAAATTTTAAAAATTTTCATTTTTTGGGTTAAAAAAAT
+CTTAAAAACAACCATAATTCTCAGGAAACTCAAATTTTTCGCCGAAAAAC
+CCATTTTGCGCGTGAAATCTGGTGTATTTTACCGTGCCTAGGCTGTGTGA
+GAACACTGCCGGTCATACATTATATTTGACGCGCAAACTGCAAAAATCGT
+CGGAATTATTTCGGGAACACAAAATTCTGAAAATGCGTATCGCGCAACAT
+ATTTGACGCGCAAAATATCTCGTAGCGAAAACTACAGTAATTATGTAAAT
+GACTACTGTAGCGCTTGTGTGTCGATTTAAGGGCTCAATTTTCAAAAAAT
+CGAGATCCCGTAAATCGACATAAGTGCTATAGTTGTTATTTAAAGAATTA
+CTGTAGTTTTCGCTACGAGATATTTTGCGCGTCAAATATGTTGTGCAATG
+CGCATTTTCAGAATTTTGTGTTCCCGGAATAATTCCGACGATTTTTGCAG
+TTTGCGCGTCAAATATGATGTATGACCGGCAGTGTTTGCCCACATCGCCT
+AAGCACGGTAAAATACACCAGATTTTTCGCGCAAAATGGGATTTTCGGCG
+AAAAATTCGAATTTCCTGAGAATTTTGGTCGTTTTTACTATTTTTTAATC
+CAAAAAAAAATGAAAATTTTTAAATTTTCTATAAATTTTCTGAAATTCAC
+CGTCGTTTTTCACGAAATAAAAAAATTTCAAAAAATTGAAAATTCCGCCA
+CATCACATTTGACGCGCAACTTTTTTAAAATGAAGAAAATCCGGATTTTT
+CTGGGAAATTTGAGATTTATTTAGGTCTCGCAGTGAAAAAAAAATTAGAG
+TTTGCGCGTCAAATATGATGTATGACCGGCAGTGTTTGCCCACATCGCCT
+AAGCACGGTAAAATACACCAGATTTTTCGCGCAAAATGGGATTTTCGGCG
+AAAAATTCGAATTTCCTGAGAATTTTGGTCGTTTTTACTATTTTTTAATC
+CAAAAAAAAATGAAAATTTTTAAATTTTCTATAAATTTTCTGAAATTCAC
+CGTCGTTTTTCACGAAATAAAAAAATTGATAAAATACACGATAAAATACA
+TCAGATTTTACGCGCAAACTGGCAAAAAAATTGATTTTTTGGCTTTTTCG
+GACTAAACATTAGAAAAAAGACTATACTCCAACAATTTTTTTCAGTTTTT
+TTTTTGAAATTTTTTTTTTTTCAGTTTAAAATGTTTTCATCGCTTTGTTC
+GTTTATTTTTGTCTGTTTATTGTGATTTTGTGCGAAATTAATGTAAAAAT
+TTCCATATCCAACACTGTTGTGTGATTAATTCGGATAGATAAAAAATGTT
+CAGCATGTTGAGTTTAGTTTTCGTCGTCCAATTTAGCTTTTTTTTGATTT
+TCAGTCAAGATTTTCTTTCGCCTTCCGCTTTTTGACTTTTCTATGCAGTA
+ATGACCAGTCTTGATTTCTAGCTTTTAGTGTTTGGTTTACCATTCTGCTA
+TTACATGAGTCACACCTTATCACTAATATAAATGCAGCATAATTTCAGAG
+TGAGCAAGCCGCGAGTATTAAACCAGCGCTGTTTTAAACTGATAATGATT
+GCAGTTTCCTTCATTCTCACCGAATATCAATTTTTATTCATTCCAGAGTC
+TCTCGAACTATGGAAAAACAACTAAAAGCTATGTCCGTCTCGGACAAACC
+TGCTGCCCCAGCTGCCCAAAAGCTTGGTACCGCTCCGCTCGCTGCAAAAA
+AGACGAGAAATGAGGAGTGGGGAACCAAGGTCAATATCGATACCAACATT
+CGCAAATTGAGTAAGTTTTTATTTTACAATTACCAGTCGTTCGAGCTTAT
+ATATCAATATTTTTTAGCGATCAAACCGAATCAGCCAATTTACAAGTACG
+CTGTGCAAGTGAACTACGTCTTCCGGAAACCTGATGGAACTGAGGCGACA
+ATCGAAATGTCCAAATCAGCCAAAAAGGGAACGGAGCACGACAACGACAA
+AACACGCTGCCAGAACGTTTACAATGAGGCGATCAAGCGTTACGATGAGC
+TGAAAACCGGAGGACCGTTTTTCTACGATCGTCAAGCCTCTTTGTACACT
+CTGACCAAATTGAAGAATGAGGTGAATTCGATTTTTTGCTTAAAGTTTAA
+TATTTTGCGTTTCAGAGCATCTCTTTCGTTGTTACTGACAAGATTTGCAA
+GCGACAAAACTTCAAAGAGGCACAGTTTGTTCTCAAAAAGGTGGATCAAT
+CGTTCCAGTCAACATCGAATGACGTCATCAAGACAACCAACTCGTGCCCA
+GCCAATGCCGACAAAACTTTGCTTGAGGCAATGAACATCATTGTCTCGGG
+ACCAGCGTTCGAAAAGTATGCCGCTTTCAGAGATAATCAAGCTATTTCAT
+CTCGTTTTCAGCAAAAATGTTATCACCGTTGGAGCATGCGTTCATTACCT
+CATCGACCCAACTGGAGTCGAGTAAGAAACTTTAAGAAATTATCATATTA
+GTATTTAATTGTTTTTTCCAGCGTCGCGTACAAGGAATACCCTGAAGGAC
+AACTCTACTCAGGAGTTGGTGTTTCAAAGTCGGTGAAGACATTGGAAGGA
+ACGGACAAGAAAGTTCCATCACTCTTCATGACAACTGAAAGTTAGTTTTT
+CAGAAAATCTAGATTTTTTTCAAAATGTTATAAAATTGTTAATTTTCAGT
+GAAGACAACATTGTTCCATCCGGATTATGCCCCACTTGTGGAACTTTTGC
+AAACGTTCAGAGGTTTCAGCACAACTCTCAAAGCGAATTCTCCAGCCGCG
+CAGAGAATTGAGAAAGCCTTTGTTGGACTGGATGTTGTCTTGAATTACGG
+TGTGCACAAGGGTCTCGGAGAGGATGGTGTCGTTATGAAGATCCGTCGAT
+TCCACACGTCAGCTAAGGAGACATGTTTTGAAGTTGAGAAGTCAACTCGT
+GAATTCACGAACGTCTTTGACTACTTCAAAAAGAAGTATGGAATCACTTT
+GAAGTATCCCGATTTATTCACCATTGAAGCGAAAGGGAAACAAGGAAAAA
+TTCATTTCCCTGCGGAAGTTCTCCTTCTCTGTCCGAACCAGACGGTCACG
+AATGATCAAATGATCAACAATGAGCAGGCGGACATGATTAAGGTAATTTT
+ATATTTTAAAATCTGAATAATATCCCGAATCCTTTTTCAGATGTCAGCCG
+CACAACCACATATCAGAAAGACGACAACTGATACTATCGTGAGAAACGTC
+GGATTGGCTTCCAACAATATCTATGGCTTCATCAAAGTTGAAGACCCAGT
+CAACCTTGAAGGAATGGTTCTTCCAAAACCTAAGATTGCGTTTGCCGGTA
+ACCGACTCGCTGATTTGGCAAATCCGAAGTCTAGATTCCCCACCGACTTC
+AATCGTGCTGGACAATATTACGATGCCAAGGAATTGACGAAATGGGAACT
+GGTCTTTGTTCAAAACGAAGAAGTCCAGTAAGTTTCAGTTTGTAATTTTT
+CATTTTATTGACTCAATTTCAGAGGACTTGCTAAGCAGCTCGCCGATGAA
+ATGGTGAATAATGGTATGAAATGCAGCAACCCAACGATGAGTTTCATCAT
+TAGAGGTGATTTGGAACCAATCTTCAAGAAAGCGAAGGCTGCTGGAACGC
+AACTTCTCTTCTTCGTTGTCAAATCTCGTTACAACTATCATCAGCAAATC
+AAGGCGTTGGAGCAAAAGTATGACGTGCTCACTCAGGAGATTCGCGCTGA
+AACCGCCGAGAAAGTCTTCCGTCAACCACAAACTCGTCTTAACATTATCA
+ATAAGACGAACATGAAACTCGGAGGACTGAACTATGCTATTGGGAGTGAA
+GCGTTCAACAAGCCAAATAGATTGATCGTTGGATTTGTTACTTCTCAACG
+AGTTGGTGGAAATCCAGATGTGAGTCATGTGTTACAGCTGCATAATCATA
+TTTCATTTTTTCCAGTATCCAATATCAGTTGGATTTGCTGCAAATATGCT
+CAAGCATCATCAAAAGTTTGCTGGTGGATACGTGTATGTTCATCGCGATA
+GGGATGTTTTCGGATCCATCATCAAGGATACTCTCTTGACAATCTTCAAA
+ACATGCACTGAGCAGCGCGGAAGACCAGATGATATCCTTTTGTATTTCAA
+TGGAGTTTCCGAAGGTCAATTCTCAATGATCAACGAGGAATTCAGTGCCC
+GAGTGAAGGAGGCGTGCATGGCATTCCAAAAGGAGGGAACCCCGCCATTC
+AGACCACACATCACCATCATCGCCTCATCAAAGGCTCACAACGAGCGTCT
+GTACAAATCCGACAAGGGACGTATTGTTAATTTGGAGCCGGGTACGGTCG
+TGGACCATACCATTGTGAGCAATGTCTACACTGAGTGGTATCATGCCTCA
+GCTGTTGCTCGCCAAGGAACTGCAAAGGCTACCAAGTTCACTCTCATCTT
+CACCACTAAAGCAGGCCCACAAGCTGAGCCATTGTGGCATCTCGAGCAAT
+TGACCAATGATCTTTGCTACGATCATCAGATTGTCTTCCATCCGGTCGGA
+CTTCCCGTCCCACTGTACATTGCTGATCGTTACAGTCAACGTGGAGCAAT
+GGTTCTTGCCGCCAATCAAGGGTAAGTGACAGTAAAATGTATACGACATC
+TCATTTATTATTTTCAGTCCAATCTACAATGAAGGACAAATCGATCTCGC
+GGCTACCAACAGTGCATATGGCTACGGAGAGAAGAAGCTCTTCACCACTC
+GTTTCAATGCATAATTATCTGTACTCCTCCGTTTCTTTTACTTGGCTGTA
+TAATGTTTTATTTCCGTCAACCCAGAATACTTTCGCTATGATTGTATATT
+TTTTAGCATTTGGTCATTGTAATTTGTAATTATTGTCGGAATGGATAAAA
+TGATTTAAGAATCAAATGCATCGCTTCTTGGACAATTCCTGTTGATAATC
+TCATTCTGATATTTTCAAAAGTTGTGGTATTGATTTTAAAAATTAAAATA
+TTTGCAGCTGCCGCTGTGACTGGAGAAGTTGATGTTTTATTTCTTCCAAT
+TCAGCTGTTTGTACCTGTTTTGTAATGTTATTACTTTCTTTCGAACAAAA
+TGTCATTCTTTTTCTGGCAGAAAATTCCGCTTTTTAAAAATTATTTTTAC
+AACATTACAGATGGATCCTTCTGTTGTGTCTCGATTGGAGAATGTTGCGA
+ATCGAATGGAGAATATATTGCTGAAATATGACTCGAACAAAAAAGGCAAT
+TAAATAATTGTTCTCGAAATTATAAATTTCAAAAAAATCGCTTTTTAGAA
+ACTCCGGTCGGCGCGACGCCTCAAATCATTAATCTTTATGACGATGCGAT
+CTGTGAGAATCTCGTCTCGTTTTATGATTTATCTGCAAAAATTGGAGGAG
+ATTTGAATCGCCTTGGATGCATGGTAAGGAAATATATAATATTTAATTCA
+AATTTTATCGAAAATTATGTTTCAGACTAAGAATCTATTTTTCACGCTTT
+TTTCGATGTTTTTTGTGGATTGCGTGTGGGCGCAAAAAAGCGGACAACGA
+CGAGTTCGCGACTCTTGTGAACGATTTGACGACGGAAATTGTTGCATTTT
+CCGATTTCAAGGAGAAAAATCGAAAATCCGAATTCTATAATCATATTTGT
+GGACTTGAAGCTGCGGTTGGAGGTGAAAATTTGCCCCTGATTCCGAATAT
+CTATGTGAAAAACTCTTCATTATTTTATATATTTCAGCTTGAAATCGCTT
+GTTCATCCATTACTTTTTTCAAGCACACGCCATATTCTCATTGGAGCGCG
+CCGTGTTGTGTCGATTTACGAAATTTTCCAATTTTTTCAATTTCAGTTTT
+TAAACGAGTTTTTATTTTTGTGGGCTTTATTTTTGTGGGTTTTGCTTTTT
+GGGTTAAAAAAAATCTTAAAAACAATCATAATTCTCAGGAAACTCAAATT
+TTTCGCCGAAAAACCTATTTTGCGCGTGAAATCTGGTGTATTTTACCGTG
+CCTAGACTATGTGTGAGAACACTGCCGGTCATACATCATATTTGACGCGC
+AAACTGCAAAAATCGTCGGAATTATTTCGGGAACACAAAATTCTGAAAAT
+GCGTATCGCGCAACATATTTGACGCGCAAAATATCTCGTAGCGAAAACTA
+CAGTAATTATGTAAATGACTACTGTAGCGCTTGTGTGTCGATTTAAGGGC
+TCAATTTTCAAAAAATCGAGATCCCGTAAATCGACACAAGTGCTATAGTT
+GTTATTTGAAGAATTACTGTAGTTTTCGCTACGAGATATTTTGCGCGTCA
+AATATGTTGTGCAATGCGCATTTTCAGAATTTTGTGTAAAAATTTTTGTG
+TTTAGTGATTTTTGCAGTTTGCGCGTCAAATATGATGTATGACCGGCAGT
+GTTTGCCCACATCGCCTAAGCACGGTAAAATACACCAGATTTTTCGCGCA
+AAATGGGATTTTCGGCGAAAAATTCGAATTTCCTGAGAATTTTGGTCGTT
+TTTACTATTTTTTAATGCAAAAAATGAAAATTTTTAAATTTTCTGAAATT
+CACCGTCGTTTTTCACGAAATAAAAAAATTTCAAAAAATTGAAAATTCCG
+CCACATCACATTTGACGCTCAACTTTTTTTAAATGAACAAAATCCGGATT
+TTTCTGGGAAATTTGAGATTTATTTAGGTCTCGCAGCGAAAAAAAAATTA
+GAGTTTGCGCGTCAAATATGATGTATGACCGGCAGTGTTTGCACACACAT
+AGCCTAGACACGATAAAATACATCAGATTTTACGCGCAAACTGGCAAAAA
+AATTGATTTTTTGGCTTTTTCGGACTAAACATTAGAAAAAAAGACTATAC
+TCCAACAATTTTTTTCAGTTTTTTTTTGAAAAATTCCATATTTTCTGAAG
+TTCAAATAAATATATATTTTTTTAAAGTTCAAAAAATTCAAATTAGCGCG
+TTAAAAACGACGTATTCAGGCATCACATTTGACGCGCAATTTTTTTTTTA
+AAGAAGGATTTGCGCGTCAAATCTGGCGAATTAGGTTTGTCGGCGGAATA
+CACCGAATTTCACGCGCAAAATTTCAAACCTCAATGATAAAATCGGAGAG
+CGTATTCGAGGAAATTACGTCTTTCAACGTCTCCGCCGGAACCACGACAG
+CGAACAAGTTTTGTGTTGACTGAAAAAAAAATTAAATTTTTCGACAAAAA
+AAATTAAATTTTTCAACGAAAAAAAATTAAATTTTTCAACGAAAAAAATT
+AAATTTTTCAACAAAAAAAAATTAAATTTTTCAACAAAAAAAAATTAAAT
+TTTTCAACAAAAAAAAATTTAATTTTTCAACAAAAAAAAATTAAATTTTT
+CAACGAAAAAAAATTAAATTTTTCAACGAAAAAAATTAAATTTTTCAACA
+AAAAAAAATTAAATTTTTCAACAAAAAAAAATTAAATTTTTCAACAAAAA
+AAAATTTAATTTTTCAACAAAAAAAAATTAAATTTTCCAACAAAAAAAAA
+TTAAATTTTTCAACAAAAAAAAATTAAATTTTTCAACAAAAAAAAATTAA
+ATTTTTCAACAAAAAAAATTAAATTTTTCAACAAAAAAAAATTAAAATTT
+TCAACGAAAAAAAAATAAATTTTTCATCAAAAAAAAATTCAAATTTCCGC
+GGAAAGTGCAAAAAATTTACAGAATATTCAAATCGTTCACTTCTCCCGCT
+ATCATCTTCACGCAATTCGACACATTTTCGTCGCCATTCGATGCGGGTTC
+CCAGTGATGTATCGATTTTCAGTTGATTATCGATTTTTCGCTCCACGTAC
+AGTACACTGAGTTCCGCTTCGAGGCCATCTGAAATTTTTTTTTTAATTTT
+TTTAACGATTTTTTTTTCAGAAAATCAATAAATCTATTCAGCTGTTTTTT
+TTTAACTTTTACACAATTTTCCGTTTGAAAATGTCAAAAAAATGTGTTTT
+TGAGCCACATTTTATTCAAAAAATTTTGAAAAATTCCCTGCATTTTCGCT
+GTGGGACCCAAGAAGTGCGTGTGCCTTTAAGAATATTTCAATTTTTTTAA
+AACTTAAAACAAAGATTTAAAAAATTCTGCTTTCTAAAAATAAATAATTA
+TTTATTTTTTTGTGTATTTGTTTGGAAAAAATCAATATTTATCGATTTTT
+GTGAATTTTTTTGAAAAAAATCAATATTTATCGATTTTTGTGAAATTTTT
+TGGGAAAAATCAATTATTATCGATTTGTGTGAATTTTTAAGAAAAAAATC
+AATAATTATCGATTTTTTGTGATTTTTTCGCAAAAAAATCAATAATAATC
+GATTTTTGTAAATTTTTTAATCGAAATTCGGCTTTTTCCGGTAAAAACAT
+CAAAATTTCGCAAAATTAATCTGATTTTTTCTGCGAAAAATTTAAATTTC
+TCATAAAACTTTCGAAAAATCGAATATTTTAAAAATCAATAATTTCGATT
+TTTGGTTAATTTTTTTGGAAAAAATCAATAATTATCGACTTTTTGCGATT
+TTTTTTTTGAAAAAAATCAATAATTATCGTTTTTTTTTAATTTATTGGAA
+AAAATCAATAATTATCGAATTTCAGTGAAATTTTTGGAAAAATCAATAAT
+AATCGTTTTTGTGTGATTTTTTTCGGAAAAAATTAAAAATTATCGTTTTT
+TGTGAATTTTTTGAAAAAATTAATAATTATCGACTTTTTTTGAATTTTTT
+TTTGGAAAAAATCAATAATCATCGATTTTTTTGTGAATTTCTTGGAAAAA
+AATCAATAATTATCGATTTTTCCGATTTTTTCCAAAAAAATCGATAAATC
+AATAAATTTTCCTTACGCCACGTGTCAATTACAGTCTTCCCCACGTGGCA
+AAACGTGTAGAGCTCGCATTTCGAATTGGTTGCCGCCGAAATTTCGCGTT
+CGATTTTTCGAGTTTCCTTGTCTTTCTGAAATTTTTTTTTTCTAAATTTT
+CTGAAAAATGTTCTTCTGTAAAACCTCTTTTTCCTCTCTTCTCCGCGCCA
+TTTCGCTCTTTTTTTTATCCTTTTCCAGCGTTTTTCTCTCTTTTTCAGCT
+TCCCGAGCTCGTTTCGCATTTTCTCGGAGTTCCTGAATAAGTTTTAAATT
+TTTAAGGGGAAATTTGCTATTTGGAGAGTAAATATTTTCGCTGTGAGACC
+CGTGGACCTGAAAATTTTGATTTTCCGCTTAAAATCAACTGAATTTCGCT
+TAATTGTGATGTTTTAAGCTGAAAAAGCTGAATTTTGATTTTAAAAAATT
+GAAAAAAATTAATATTTTTAAAGGCGCATTTATTGATTTTTTTTCCAAAA
+AAAATTTACAAAAAAATTGATAATTATTGATTTTTTCCAAAAAAATTAAC
+AAAAATCGATAATTTTTTTTCCAAAAAATTCACTGAAAAATCGATGATTA
+TTGATTTTTCCAAAAAAAATTCACTGAAAAATCGATAATTATTGATTTTT
+CCAAAAAAAAAAATCACAAAAGTCGATAATTACTGATTTTTTCCAAGAAA
+ATTTTAAAAAAAAACGACAATTATTGATTTTTTCCGAAAAAATTACAAAA
+AAATCGACAAGTACTGATTTTTTCTGAAAAAATTACAAAAAATCGATAAT
+TATTGATATTTTACAAAAAATCGATAATTATTGATTTTTTACAAAAAATT
+CACAAAAAAATCGATAATTTTTAATTTTTTTCAAAAAAAAAATCACAAAA
+AATCGATAATTATTGATTTTTACCAAAAAAAATCACAAAAATCGATAAAT
+ATTGATTTTTTCCAAAAAAATTAACAAAAATCGATAATTATTGATTTTCC
+CAGAAAAAATTCACTGAAAAATCGATAATTATTGATTTTTTCCGAAAAAA
+TTCACAAAAAAATTGATAATTTTTTAATTTAAAAAAAAATCACAAAAAAT
+CGATAATTATTGATATTTTACAAAAAAAAATTACAAAAAATCGATAATTA
+TTGATTTTTTACAAAAAATTCACAAAAAATCGATAATTTTTAATTTTTTT
+CAAAAAAAAAATCACAAAAATCGATAATTATTGATTTTTTCCAAAAAAAA
+TCACAAAAATCGATAATTATTGATTTTTAGGCGGAAAAGCCGAATTTTTA
+TCAATTTTTCAAAAAAACAATCGATAGTTTTAAAGGCGCATGCGCTCTCC
+TGGGTCTCACAGCGAAAAGTGGATTTTTCAAATTTTTTGGATAAAATTTC
+GCTGAAAAACGTATTTTTTTGACAGTTTTAAAGGGAAAATTGTCTAAAAT
+CAAAAAAAAATTGTTTTTTCAACAATTTTTTCAGTTTTCGTAAAAATTTC
+AGTTTTTTTTTCGCGAGAAAAAAACCAATTCTCGATTGAAAAATCAGAAA
+AAATATTTTGGTATAAAAATATTTTTGGTATTACGATATTTTGGGTCCCA
+CCTCGAAAATTTAGAGGATTTTTCAAATTTTTAAGATTTTCTTCAACTTT
+TAACAATTTTTTTCGGAATAAAAATCGATTTTCGCTGCGAGACCCAAAAA
+AAATAGATTTTCTCGAATTTTGCGATGGAACTTTTGATTTTTCGGTGAAA
+TTTTCCAAAAAAATCGCAAAATGTATCAAAAAATCAATACTTTCTGCGTC
+TCCTTCTCATCGTCGGTTAGTTTCCGTTTTTCGGGTCTCGCCACGACATT
+TATGTCAGTATTCTCTTGTGAGCTTGAGCACAACGAGTATGAGCTCGTCT
+GATTCTGACGGATCATTTCGTCAAGATTGAGCATTCCCTCATCCAGCCAT
+GTTTTTGCCGCAGCTGGAATTGCATCCTTATTCACTGCGTCGACGATGGA
+AAAGCTCGCGGAGTACCTGGAAATTATCGATTTTTTATTGATTTTTTATC
+GGTTTTTATCGATTTTTTTGATGGGGAAAAATCGGAAAAATCGATAAATT
+TCGATTGGAAAATTCAAAAAACTTCGGGTCTCACAACGAAAATTGATTTT
+TTTTCTTGGATTTTCAAATTTTTAAACTTTTGTTGTAACAACAGTGGAAA
+TTTTTCGAAAAAAAATCAATAATTATCGATTTTTTGAAAAAAGGCAATAA
+TTTTCGATTTTTTGAAAAAAAAAATCAATAATTATCGATTTTTTGTGAAT
+TTTTGAAAAAAATCAATAATTTTCGATTTTTTGTGATTTTTTTTCGAAAA
+AATCAAAAATTATCGATTTTTTGTGGATTTTTTGAAAAAAATCAATAATT
+ATCGATTTTTTGTGGATTTTTTGTAAAAAATCAATAGTTTTCGATTTTTT
+TTGGAAAAAATCAATAATTATCGATTTTTTGTGGATTTTTTGAAAAAAAT
+CAATAATTATCGATTTTTTTTTGAATTTTTTGAAAAAAATCAATAATTTT
+CGATTTTTTGTGATTTTTTTTCGGAAAAATCAAAAATTATCGATTTTTTG
+TGAATTTTTTTTTGGAAAAATCAATAATTATCGATTTTTGTGATTTTTTG
+TAAAATATCAATAATTATCGATTTTTTGTGATTTTTTTCGGAAAAATCAA
+AAATTATCAATTTTTTGTGATTTTTTTTTTGGAAAAATCAATAATTATCG
+ATTTTTGTGATTTTTTTTGGAAAAAATCAATAATTATCGATTTTTGTGAA
+TTTTTTGTAAAATATCAATAATTATCGATTTTTTTGTAATTTTTTCGGAA
+AAAATCAATAATTTTCGATTTTTTGTGAATTGATTTTTTTTGGATTTTCA
+AAATTTTAAACTTTTAAAATAAATTTTTCCATAGTTTTTTGTTGAAAAAT
+TCCTGAAATTTTGAAATTCAATTAATTTTTTCTTTAAAAAAATCGTTGAA
+AAATTAGTTTTTTGGAAAAAAAATCAGCGAAAATAGATTTCGCTGTGAGA
+CCCAATTGGGCTCCTCAAAGTCCCTGCGCCTTTAAAATATCGTTTTTTTT
+TTGTTAAATTTTCCCGCGAAATTAATCAGATTTTTTCTGCGAAAAAGTGA
+AATTTCTCAAAGAAACTTTTGAAAAATCAATTTTTTTAAAAAGAAAACCC
+CTAATTTTTCCGTTTTTCCCGCTAAAAAAACATCTAAAAAATTTGAAAAA
+TCCACAGAATTATCGCTGTGGGACCCAAAGTGCATGCGCCTTTAAGATTA
+TCGATTTTTTTCAAATTTTTCAATCGAAATCAGGTTTTTTTTTTCAGCAA
+AAATCATAATTTTGCGAAATTAATCTGATTTTTTGTGCAAAAAATTCAAA
+TTTCTCTTTTTTTACGTTTTTTCGCCAAAAAAACCATCTAAAAAATTCGA
+AAAATCCAGAGCATTTTCGCTGTGAGACCCAAGTCCGTGTGGCTTTAAAA
+ATATCGATTTTTTGTTAAATTTTCCAATCGAAATTTGGCTTTTTTTCCGG
+TAAAAAATCATAATTTTGCGAAATTAGTCTGATTTTTTGTGCGAAAAAGC
+GAAATTTCTCATAAAACTTTTGAAAAATTGATTTTTTTTTTCTGGAAAAA
+CCTATTTTTGTCGTTTTTTCGCTAAAAAACATCTAAAAAATTCGAAAAAT
+CCCCAAAATTTTCGCTGTGAGACCCAAGGCTCCTGAAAGTCCCTGCGCCT
+TTAAAAATATCGATTTTTTGTTAAATTTTTAATCGAAATTCGGCTTTTTC
+CGGTAAAAACATCAAAATTTCGCAAAATTAATCTGATTTTTTCTGCGAAA
+AATTCAAATTTCTCATAAAACTTTCGAAAAATCGATTATTTTCCGCTAAA
+AAATCATCTAAAAACTCGAAAAATCCAGACAACTTTCGCTGCGAGACCCA
+AGTCCATGCGCCTTTAAAAATATCGATTTTCTGTGAAATTTCTCACAATT
+TCTCCAAATTTCCCGCCGTCACATTCGTCGTTTCCTCAATCATAATACAG
+TCCTCATCATCATCATCATCCGAGAGGACTACAATCGCCTCGTCCATCTG
+AATAGTGGGAAAATATCGATTTTTTGTAGAAAATCATATATTTAAATTGA
+TTTTTTTACAATAAAAAAAATTTTGGGGATTTTTTTGGAAATTTCGGGTA
+AATCGTGTAAATCGTGTAATTTAAATTCATTTTTGTTTCAAAAAGTCAGG
+GGGGGGGGGGGAAAGAAAAAATTTTTGACAAAGCGTGGAGCGAAAAAAGG
+AGTAAATATACAGTCGCGAAAGAACGATCGCTCCGCCAATTTTGCATGCG
+GCAAAGGGGCGTGGTTTATTGGGGGCGGGATTCCGGCGCAACCCTGCGGC
+ACGCTTTTTTCTCGCTTTTTTCGTGCGGTAATTTTCAGTTATTTTTATTC
+GTTTTCTGTTCGAAATTTCACGATTTCGCTCGATTTTGTTCGTTTTTTCG
+GATAAAAAAGTGTCCAACTATTTTTTAAATGAAAAATAACCAAGTTTTCA
+CAGATTTTACCCGAAAAATGCTTTGTTGGTCTCTCTTTCTGTAAATTACG
+ATTGTTAAGAGAGAAAATGGGGGAAAAAAAGGAAAATGTGAAGAGAAAGC
+GTTTTTTTAACGTTTTGCTTCGTATATTACAGAAAAAGAGACAAACGAAG
+CATTTTTTCAAGTAAAAACTGATAAAACTTGGTTATTTTTCATTTAAAAA
+TAGACACTTTTTTATCCGAAAAAACGAACAAAATCGAGCGAAATCGTGAA
+ATTTCGAACAGAAAACGAATAAAAATAACTGAAAATTACCGCATGAAAAA
+AGCGAGAAAAAAGCGTGCCGCAGGGTTGCGCCGGAATCCCGCCCCCAATA
+AACCACGCCCCTTTGCCGCATGCAAAATTGGCGGAGCGATCGTTCTGTCG
+CGACAGTATGTAACATGTAAGGTAACAAGGTGGGTTGGTTTTCATGAGAA
+AAGGGGGATTTTTTTCCGATTTTTCAGGTGCAGAGCCCACGCTCTCCTCA
+AAGCCGAATAATTATTAGAGCGCGCTTGCAGCGACTCGCGTTTCTGCATC
+CGCGGTATTTTGACTTTCCACTGAAGAAAGCAGATATTTCAGATTTATCG
+AATTTTTAGGTTTAAAATTTTTTTTTTCTGTATTTTTCGAACAAACCTTT
+TGTCAAACAGTAAAAATCGAAATTAAAATGACTAAAATGAACTTTTTTTG
+TCCACTGGTTGTGAAATGGTTTGAATTTGAAGAAATCAACGGGGTTTTTC
+GTATTTTCTGAATATTGTTCTATTAAAAATTGGTTTTAATACATTTTTGA
+CTTAACATTAGGGTCAAAAAATGGTTTAAAACCGATTTTTAATAGAAAAA
+TATTCAGAAAATACGAAAAATCCCGCTGATTTCTTCAAATTCGAACCATT
+TCGCAACCAGTGGACGAAAAAAGTTCATTTTAGTCATTTTAATTTCGATT
+TTTACTGTTTAACAAAAGGTTTGTTCGAAAAAAACAGAAAAAAAAATTTA
+AAAGCTAAAAATTCGATAAATCTAAAAAAGCTGCTCATTTCAGTGGAAAG
+GCAAAATACCGCGGATGCAGAAACGCGAGACGCTGCAAGCGCGCTCTAAT
+AATTATTCGGCTTTGAGGAGAGCGTGGTGCAGAGCCCCAATTTTAAACAA
+AAAATAGCGGAAAAAAATATTTAAAAAAACGAGGATTAAATAAAAATTAA
+ATAATGTCAGCAATGTTCATTGGCATCTCGTCGATTTGTGTCGAGTAGTA
+CTGCTCAATGTCGCGGAGAATTCGTACGTCGTCCTGTTTGACGAAATTGA
+TGGCGACTCCCTTGCGGCCGAAACGTCCCGAACGGCCGATACGATGGATG
+TAGAGCTCACGGTTGTTCGGCAAATCGTAGTTGATTACCTGGAAAATTTT
+TTGATGAAAAGCTGATTTTTGCGATTTTCGCCATTTTTTGACCTAAAAAA
+TTGGCGAAATTCGGAATTTTTAAACAAATTTTGACGTAAAGTAGGTTAAA
+ATTCCAAAATTTTACGGTAAATAGCCTGAAATGCTTTAAATTGATCCTTT
+TTTGCACAATTTTAACAATGAAAACCTGTATTTTTCGCTACTTTTAGTTG
+AAAAAAGCTTCCAAAACGAGTAAAATTGGCAAATTTTATCGATTTTCGCA
+AATTTTTCACCTAAAAATTGAAGAAATCGGTATTTTTAAACAAATTTTGG
+CATAAAGTAGGTTAAAATACCAAAATTTTACGGTTTTTAGCAATTTTTGA
+GTCAATTTTCAAAATGTTCCAGTATTTTTGCAACTATTTGGTTTTTATTC
+ATCTATGTTCTTTGAAAATTCTTTTTTTTAAGGTGAATTAGGTTAGAAAG
+GGGTCGATTTTGCAGAATTTTGACAGATTTCGCATGAAAATTTGAATTTT
+CAGGCGAAAATCATCAAAAATATGATTTTTTGCTACTTTTAGTTGAAAAA
+AGTGTACAAAACGAGTAAAATTGACAAATTTTTATCGATTTTCGCCATTT
+TTTCACCTAAAATTTAATTTTTTTTTTCTAGTGAAATAAGTTAAATTCAG
+TGTTAAAATGTATCTATTTTCGCTCAAAATTTGAAAATTTTCAATTTTTC
+ACTGAAATCCATGAGAAACCAGTGAAAAAATTTTTTCAATTTGAAAATTT
+GCAGTGAATTTTATTTTTTCTGCTAATTTTTCGGTGAAAAATGCACTTTT
+TCACGAGAATTAGCGGGATTTTTGTATTTTCAAAGTTTTTAGGTCAATTT
+TCAAAATGTTTCTCGCTGAAAATTGATTTTTTGTCAATTTTTCACATATT
+TTCTATGAAAAATTCCACCTTTTTGCAGAATTTTGACTAAGAAATACGAT
+TGTCGCCTAAAAGTTTGAATTTTTCAATTTTTTTTTGCTGAAAATCATCA
+AAAATACGATTTTCAACAGAAAATGATGAAATTTTCGCTATTTTTCGCGG
+AAAATCATTGATAACCTGATTTTTTCGCTACTTTTAGTTGAAAATAGTTT
+ACAAAACGAGTGAAATTGGCAAATTTTATCGATTTTCGCAAGTTTTTAAC
+CTAAAATTTAGTTTTTTTCTAGTAAAGTAGGGAAATTCAGTGAGATTTTT
+TAATTTTTCACTGAAATCCATGAGAAATTAGTGAAAAAAAAATGTTTTTG
+GCCAACTTTTCACATATTTGATATGAAAAATGCCGTTCTGAACAAAAAAA
+GCTGTGGAAATTCAACTTATTGTCAATTTTCCGCTGAAAAATTCATTTTT
+TTTTCTCAAGAATTCGCATTAAAACTGCGGAATTTCTTGTATTTTCAGCA
+GAAAATGATGAAATTTTCGCTATTCTTCGCGGAAAATCATTGAAAACCTG
+ATTTTTTCGCTACTTATAGTTTAAAATAGTTTACAAAACGAGTGAAATTG
+GCAAATTTTATCGATTTTCGCAAGTTTTTAACCTAAAATTTAGTTTTTTT
+TTCTAGTAAAGTAGGGAAATTCAGTGTCAAAATTTACTTATTGGGTAAAT
+GGAAATTGTGAATTTCCATTGTAAAAATTTCTGCTGGGAAATTCATTTTT
+CCCAAATTTTTCATATAATTAGGCTGAAAAATGCAATTTTTCACAAGAAT
+TCGCATTAAAACAGCGGGATTTTTTTTGTATTTTCAACGGAAAATGCTAT
+TTTTTGCGGAAAATCACTGCAACTTTTTCCTCACGAGGGCCAAGGAAAAG
+TGGTTTCTAGGCCATGGCCGAGGGGCCGACAAGTTTCAGCGGCCATTTAT
+CTTGCTTTGTTTTTCGCCTGTTTTCTTTCGTTTTTCACAGCTTTTTCCCG
+TTTTTTCTTATTAAAACTGATAAATAAATATTTTTTGCAGATGCTAAAAC
+AATTTCCAAGTAAAAAAAATTATGTATTCAGTCGGCAAGCAGCGGTGAAA
+GTGGGCAATGTAAAATGATGGATTACGGGAATACAAAACCTGAAATTTTT
+CTGAAACATGATACATATGCTGCTTAGATGCTGATACTACCTGATTTTCA
+TAACGAGACCGCTGAAAAGTTTTGAGGTTTCCACAATTCAACTTTTTTGG
+TGAAAAAATCGAGATTTTCGCACAAAAAGTTGAATTTTGAAAACCTCAAA
+ACTTTTTCAGCGGTCTTGATATGAAAATCAGGTAATTTCAGCATCGAAGC
+ATCATATGTATCATGTTTCAGAAAAAGTTTAGGTTTTGTATTCCCGTAAT
+CCATCATATTGCATTGACCACTTTCACCGCTGCTTGCCGACTGAATACAT
+AATTTTTTTACTTGGAAATTGTTTTAGCATCTGCAAAAAATATTTATTTA
+TCAGTTTTAATGAGAAAAAACGGGAAAAAGCTGTGAAAAACGAAAGAAAA
+CAGGCGGAAAACAAAGCAAGATAAATGGCCGCTGAAACTTGTCGGCCCCT
+CGGCCATGGCCTAGAAACCACTTTTCCTCGTCCCTTGTGAGGAAAAAGTT
+GCAGTGGGAAAATGCTATTTTTCGCGGAAAATCGAAAATGTACCAAGGAC
+ACTTGCGGAACATCAAGTCCTCTCGCCCAAACATCAGTAGAAATGAGGAC
+ACGAGTGGTTCCAGCTCTAAACTCCTTCATAACCTCATCACGATCCTTCT
+GCTCCATATCTCCATGCATCGATGAGACGGTAAAGTTGGCCTCCTTCATC
+TTATCAGTCAACCAGTCCACCTTTCTACGTGTATTACAGAACAACACCGC
+CTGAGTGATGGTTAAGGTGTCGTAGAGATCGATAAGCGTGTCGAACTTCC
+ACTCCTCCCGATCAACTGCGACGAAGAACTGCTTGATGCCTTCCAGTGTC
+AACTCGTCACGCTTCACAAGGATCCGAATCGGATCCGTCATGAATTTACT
+CGTCATCTCCAGAATCTCATGAGGAAGCGTCGCGGAGAGCAGCACCACCT
+GGGCTCCGGGCGGTAGATAGCGATAGATATCGTAAAGCTGCTCCTTGAAC
+CCCTTGTTGAGCATCTCGTCGGCTTCATCGAGCACGAGAAGCTTGATGGC
+GCGGGTGCGCAGGTTTCGACGGCGAATCATGTCGAAAACGCGTCCCGGAG
+TACCGGAAACCACGTGCTGGCCGTAGTCGAGCTTTCGGATGTCCTCGCCG
+AGATTGGTGCCTCCGATACAGGCGTGGCACTGGACATTCATATAGTCGCC
+GAGCGCCAGCACGACTTTTTGAATTTGAACTGCCAGCTCTCGTGTCGGCG
+AGAGAATCAGAGCTTGGGTCTCGCGGACCTGGGTGTCTAGCGATTGGAGT
+ACGGAGATCGAGAATGTCGCCGTTTTTCCTGTTCCGGATTGAGCTTGAGC
+GATGACGTCACGAGCCTTGAGAATTGCGGGGATGGCGCGTTGCTGGATGG
+CAGATGGCTTTTCGAAGCCGTACGCGTAGATTCCACGAAGCAAGTCTTCT
+CTGGAAATCGAAAAAAATTTTGAATTTAGTTTTATATTTAAAGGTGGTGT
+AGTCGAATTATTTATTTCTTTATTAGACTCAAAATTGTCTGAAAAAAAAG
+TGTACAAAACGAGTAAAATTGGCGACTTTTATCAATTTTCGCCATTTTTC
+ATCTAAAAAAATCGACGAAATTCGGAATTTTAAACAAATTTTGACGTAAA
+GTAGGTTAAAATTCCAAAATTTTACGGTTTTTAACAATTTTTCCACCTTA
+AAGTTGGTGTAGTCGAATTATTTTTTTCTTTATTAGACTCAAAATTGTCT
+GAAAACACCGAATTTCATAATGAAACTTCTTGAAAACTGAAAACTTTTCA
+AAAAAAAGTTAAGGCCTCTTGAAAAAAGGCCTAAAATTAGTGAAAATTTG
+AAATTTGACCAACTTGTCTGTCAAGCGGCTGGAAACAATTTTCTTTGAAA
+TTGTCGTCTAATTTTGGGTATACAGGTCGATTACCTTGCGTTTTCAGCTT
+TATTTAGGTATTTAAAAGTCGATGGACGAAGAGATTTGTCAAATTTTTTT
+CACCAACTATCTTCGTCCATCGACTTTTAATACCTTAATAAAGCTGAAAA
+CGCAAGATACGACCTGTATACCCAAAATTAGACGACAATTTCAAAAAAAA
+TTGTTTCCAGCCGCTTGACAGACAAGTTGGTCAAATTTCAAATTTTCACT
+AATTATAGGCCATTTTTCGAGCCGCCATAACTTTTTTTTGAAAATTTTTC
+AAGAAGTTTCATTATGAAATTCGGTGTTTTCAGACAATTTTGAGTCTAAA
+AAAGCAATAAAAAAAATTCGACTACACCAACTTTAAGGTGGAAAATTTTT
+TAAAAACCGTAAAATTCTGGAATTTTAACCTACTTTACGTCAAAATTTGT
+TTAAAATTCCGAATTTCGTCAATATTTTAGATGAAAAAATGGCGAAAATC
+GATAAAATTTGCCAATTTTACTCGTTTTGTACACTTTTTTCAACTAAAAG
+TAGCGAAAAATCATGTTTTTGATGATTTTCAGCTGAAAATTCAAATTTCA
+GGCAAAATTCTGCAAAAAAAGGGTAATTTTTCAGAGAAAATATGGGAAGA
+ATTGAAAAAAAAAACTGTTTTCAGCAAGAAAAATGTTTGAAAATTTACCT
+TTAAATTTTTAAAAACCGTAAAATTTTGGAATTTTAACCTACTTTACGTC
+AAAATTTGTTTAAAATTCCGAATTCCGTCGATTTTTTTAGATGGAAAAAT
+GGCGAAAATCGATAAAAGTCGCCAATTTTACTCGTTTTGTACACTTTTTT
+CAACTAAAAGTAGCAAAAAAATAATGTTTTGAGGCGAAAATTTGTTTTCA
+GCGACAAAATTCTGCAGAAAAAGTTCAATTTGAAGCTTTTCTGGTTATTT
+ATAGAGAATTTTCCGTTAAAATCGATAATTCAATACCTCAAGCCCATTTT
+GTCAAAAGTTGGGATAATTGAGACCTCCTCAGACGACTCGAACTCCACAG
+TCGCCATATCGTCGTTTTTCTTTTTATTTTCCGCCATTTTTGAAGGAAGA
+ACTCTGTAAAATCGATAAAAATGAATATTTTCGAGCATTTTTGCAGAGAA
+ATTCAGCATTTTTAGGTGGAAATTATCAAAATCAATGAATTTACATCGAA
+AAAATCAAGAAAAACGTGTAAAAACGATAAAATTGATTATTTTCGGGCAT
+TTTGCAGAGAAATTCAAGATTTTTAGGAGGAAATTAACAAAATAAGTGAA
+TTTACATCGAAAAAATTAAGAAAAACCTGTAAAATCGATAAAAAACTAGT
+AAAAGAGCAAGATTTCGAATGTTTTCGAAAATACCCTGTTTTTCGAGCAT
+TTTTGCAGAGAAATTCAGCATTTTCAGGTGGAAATTTACAAAATAAACGA
+ATTTACATCGAAAAAATCAAGAAAAATGGTGATTTATCGGCTATTTTCGC
+TCATAATTCGTAGGATTCGATTCGAAACTAAAATTCGAAATTCGAAAAAC
+ATGGCCGTGGCCTAGCGTTCCCCTCCTAGTCCACGGCCGCGCACGATTTA
+CGGAGAGCACGATTATTGATCGATGACACATGGTTTCCGACTGTTTTTCC
+TGTTAAATTTACCCTTAAATCACAATTTTCCATAGAAAATGGGTGGAATT
+TTCTCGAAAAAAGAGAAATCACCAAAATCGGCGCCGGTTTCCGATCAGGA
+TAATGCGATTTTGGTTTGTTTAATGAGGTTTTTCACATGGAAATTATTAT
+TTTTTTGGTAATTCCAGGCGCTCAAAACACAACGGGACAAAATGAAGCAA
+ATGATCAAGCGAAAAGAGAATTGTTTGGAGAAGGAACGACAATTGGCAAA
+GCAGCTTATAAAGGATGGCCGGAAAGAGTAAGAAATTTCAGAAAATTCAG
+TTTTTTTTATTAAAAAAAAAAAATATATATATAAATTTTTAACTAATTTC
+AGCCGTGCTTTACTGCTTCTGAAGAAGAAACGCTACCAAGAGAAGATTAT
+CGATCAAACCTTGAACCATCTTAGCAAAATCGAGCAAATGGTATTGAAAA
+ATCAGAAAAAAATAAAAATTTTCCAGCAAAAAAATCAATAAATTTCCAGG
+TAAATGACCTAGAATTCGCAGAAGTTCAACAGCGAGTAACCGATGGCCTT
+CGACAGGGAAATGAAGCGCTGAAAAAGATGAATCAACTATTCGATATCGA
+TGAAATCGACAGGATTATGGAAGAAACCAAAGAGGCGGCGGAATATCAGG
+AAGAAATCTCGAATATGCTGTCCGGCCAGCTTTCCAACACGGATGTCTCG
+GACGTTGAGAAGGAATTGGAGGATCTGTTGGCGGCGGAATGGGGCACAGT
+TCAACTTCCAGAGGCTCCGAGCCATGAGCTGCCTGAAGCAGAGCGGGAAC
+GGCAAAAAGGTTGAGATTTGCCGAGAAAATTCCTAAATTTTCCCTAAATA
+AATAATTTTTTTTCAGAAAAAGAGAAGCCACGTCGCGAGAAGATTGCTCT
+GGAAGCCTAAATATTGCTTGTTACTGTGAATAAAATAAATTCATTATATT
+ATTATATTTTTTATACAATTTTGTCTTACTGGCGTTGTTCTGAACGAAAA
+ATTCGTTTAAATAACGCTGTAACAAAAAATCTCATTTTGCGCGTAAAATA
+AAATGCCAGTGACGCAATCACCACGACGAAAAATCGCACAGTTTTGGAAA
+ATTGCGGTTTTTCAAACTTTTTTTCGCTTTTTTCGGATGCTATTCAAGCG
+GCTATAGACTGTTCAAATAGAGATAGAACGGTCAGAAAATGAGAGACATA
+GACAAATAAAGAGACAATTTATTGACTTTTTAGGCTATTCTTTGTTGGAA
+ACCAACAAATTTTGTGTTCCCAGGCTTTTCTTTGCAAATTCTGAAGGGTT
+CTTCTTTGCAGATGCGTCGACGTGTAGCTCTGGACAATGACGAGCATGAT
+GGTAAGTTAAAAAATTGGAAAAAAAAACTTTGGTTTCTATTAAATTTTAT
+TATACTTATTCCCTTTTTATAATTAAAGGCGTCTAGCTCATTCAAGCTCA
+TTCACGACGTTAGTTGACGCATTCCTCCTTGCACGCATGGCCTAGTGGGT
+TAAGGCGCTGAACATCACTCAGAAGTCCACAAGTTCAAACCCAACGAGGC
+TCCCCCGCTTTTCTAACCCTAGCTTGAGCAATCAAATCGGAACGCGTCGG
+AGCTGTCTCGGAGCCAGAAGCCTCATCAAATATTTTGATTGCTTCCAAAC
+AATCTATCGCACGTTTGTGCTCCTCATTTCCGTAATGACGTGTGCATGCG
+TAAGCTTGATCTTTCCAGTTTTCTAGGTGACTCATTAGAGCAATCGAGTG
+AGCAACTCGTTCATTCGGTATTTCATGAGCCAATTGCTATGCGGGACGCG
+GGGCTTCTGGAAAAAAATTAAACAAATATTTTTCGTTTTTTTTTCCACAT
+GTGTGGATCTCAATTTATTTCTTCTTTTTTTGTTTACCTCATTTTATAAA
+ATTCTCCTTTTTTTCTCATTAATTTTTCTGTGGCTTTTTCAAAGATCTTT
+TTCAGATTTTCATCTATTTGTTTTAATGTGGAGCAAAATTGAAATTTGTC
+TGGTAGATACGGTAGCTTTAAAGGCGCATACTAAATTTAAAGTGACAAAA
+TAAATATTTAGTTCCATATGGAATTTCAATTTTTGCTGCCAGGCTGTCCC
+ATTACGGTTTGATCTACAAAAAATGCGGGATTTTTTTTGGCCCAAATAAT
+GTGACGTCAGTGCGTTCTTAACCATGCGAAATCAGATGAGAACTCTGCGT
+CTCAACTCCCGCATTTTTTGTAGATCTACGTAGATCAAACCAAAATGGGA
+CATTCTGACACCAGGTATTCGCCGCGGAACCAGTTTTATACCGTATTTCG
+TATGCGCCTTTAATTCTACCGTACCCGCTTCTGGAAGTTTGGAAGTTTGA
+AAAACTATTAAATAGAATTTATTAATTTTTGCATATTACTTTGTGCAGAA
+TACCTCTAAAAATATTAAAATCCAGATAAACATGGTTTTTAAAATGTTTT
+GCACAAAAAGCGATGATTTCGCTTCGAAGCCACTTTTATAAAACGCCTTG
+TGCGCCTTTAATTCCACCGTACTCGCCAAAATTAAACTGAATGAGCGAGT
+TTTGAACTAATTTTTACGAAAAAATCACGTTCTGATCGGTTCTGGTCTTC
+CTCTAAAATCGGTTCTGGTCTTCCTCTTTGAATTTTCGCGCTCCATTGAC
+AATCGCCTGCCGGACTGGGAAAGCCGTGTACTCCACACGGACAAGTACAT
+TTAGTTTTACAACTAAAATCGAGCCGCGACGCGACACGCAACGCGCCGTA
+AATCTACACCAGATATGACCGAGCCAAAATGGCCTAGTTCGGCAAATTCT
+TCCATTTCAATTTATGAGGGAAGCCAGAAATTCGTGTATTTTTACAAAGA
+AATGTGAAAAAGAAGCTAAAATTTCAATGAAATAGAGATTTTTCCCGGAA
+TCTCACAGTTTCGCAAAATACTATGGATTAAAAAACGCTGAAACCCAAAT
+TTGCGCGTAAAATTCAATGTATAGCGAACATTCACGGATTTCTGGCTTTT
+CTCATATATTGAGATGGAAGAGTTTGCCGAACTAGGCCATATCTGGGGTA
+GATTTACGGCGCGTTGCGTGTCGCGTCACGGCTCGATTTTAGTTGTGAAA
+CTAAATGCATTTGTCCGTGTGGAGTACACGCGTTGTCCGGCGGGCGATTG
+TCAATGGAGCGCGAAAAATTCAATATGGAAGGCCAGCACCCCGTGTTAAC
+ATTTAAAAATTACAAGATTTGCCCCCTCAAACATCCCTGGAAAAACTAGA
+AAAACCTCGTGTGCTTGCCTGACAACAGCTGTTCACCGACAAAAAGATGA
+CGGGGAGGGCTTCAACAGAGCTTGTGTTTCCTCGTCAACTCTTTCGAGAA
+CTGACAGCACTTTTCATATAACTCATCACTAACTTTCGCTGCTCGTGGCG
+GTTTTTTTTAGTTCCCCAGTAATGAGTCAATTTTGTCTGTTGCTCAGAAC
+TCTCAATTACCGATGCTATTAGCGGAAGGACTTTTGGAGCGCCGGAGCCA
+GAGCAAAATTCATTTTTATTTGAAAAATGAGTGATGAGTTTTTCTCTCTG
+TTTTTCCATGTTTTTCTCGTTATTAGGCTGTAACTTTCCACATACACTTG
+GTGTCAGAGAGTCCCATCACGGTTTGATCTACAATAAAAGTGTGACGTCA
+GCACGTTCTTAACCTTGTGACAATAGTTGAAAAATCTGCGTCTCGTTTCC
+CGCATTTTTGTAGATCACACCGTGATGGGACTCTCTAACACCACGTACAC
+ATGAAAATTTCGCTGAGAACAAATTTTTGCGCGTCAAATCTGATGTATCC
+GGACTGTACCGATATCAATACATCGAATTTGACGCGCAAACTCCGTTTTC
+ATGGGGAATTGTTGAAAAAATTGTTTAACTTCCGGAAAATTAACATTTTT
+CAGAGAAAATCAAAATTTTTCTGTTTTTCCTTAAATTTCTAGGAAAATTG
+TAGCAGATTTTGTTGAAAAAATTCAAATTTCCACTGAAAAAAGTGAAAAA
+AGAAGACGATGTGTAAGCCTAAGCCTAAGCCTAAGACTAGGTCTAAGCCT
+AAGCCTGAGCCTATGCCTCAGCCTGAGAATAAGCGTGAGCCTAAGCGTGA
+GCCTAAGTCTAAACCTAAGCCTAAGCCTAAGCCTGATCCCAAGCCCACAT
+GGTGCCAGGCTGACCCATAACGGTTTGATCTACAAAAAATGCGCGAAATT
+TTTTGCCCAAAAAATTTGACGTCAGCGCTTTCTTAACCATGCGAAATCAG
+TTGAGAACTCTGCGTCTCTTCTCCCGCATTTTTTGTAGGTCTACGTAGAT
+CAAGCCTAAATGGGACACTCTGACACCACGTGAAGCCTAATCCTGAGTCT
+AAGCCTTATCCAATTTCCGAAAAATCAATAAAAATGCAAATAACATAGAT
+ATTCCCGCCTAAAGTTCAATAAATTATTTTTTTTTTGAAACTTTTTTCAA
+AACTTGCGAATGCATAGTACCAAAAAACGCCATATTTGACACGCAATTTT
+TGGATTGACTTTTTTTTGAATTGATATGTCATGAGCATCACTCAAGTGGT
+TCCAAAAAGGCGTCAAGTACTTGAGCCCTCCCTGAGCCACCACCGTCTCC
+AGAGAGCAGCCGAAACCAAAAACAAATAGGGGGAAAATGAACAGTTCTCT
+CTGTTTCAAAATCTATATATTCCTGTTCTTTGTATTATCTTCCGTGCGGC
+TTCAGCCCTCTACTGCTGCTCCAATTCTTTTCCATGTTATTTACCGTACC
+GATTAGACGAATGAACAGGACCCCCTTTTACCGTTCAACCGATGAGCCAA
+TGTGCTCTTTGTTGGCTAATTTGGGTGTTTTGCTCATTTGGAGGAACACT
+AACTTCCCTCTCTAACTACACACTACGTGGAAGAGTTTTTTCAGATTTCT
+AGGCCTCGCAACTTTCCTTGGTGGCCCAGAAAAACGCTTAAAACTTCAAG
+GTCAAAACGTTCATTTTTGTTGAAAAAAATCGGTTTTTACTTGAATTTTT
+GTAAGTGGAAGAGTTTCCTAAATTTCTAGGCCATGTGCTTTTTCCTGCTT
+ATCTGAAAATTTTGTTCAAATTTTCTTTTTTCACTTAAATATTCCCCGAA
+AATCTTGTCCACAAAAAGAAATTTTTGAACATTCAGATCATTTTTTTAGA
+ATGGAAGAGTTTTCCAGATTTCTAGGCCACATGGCTTTTCCTGGTGGCCT
+AGAAAATTTTCTGTTGGAAGAATCAGGTTTTTACTTGAATTTTCGTAAGT
+GGAAGAGTTTTTTACATTTCTAGGCCACGTGATTTTTTCCTGATGGTCTA
+GGAAACTTGTTTTCTCTAATTTTCCCCGATTTTGGATAATATTTGTTTAG
+TGGAAGAGTTTTCAGAAATTCTAGGCCACGTGGTTTTTTTTGGAAAAGAA
+ATATTTAGATCACATTAACATGTACTTTTATCAGATTTTTTGCCAAAATA
+CCAATTTTACAAGCTATTTTTTTGTTATATGTAAATTTTGTGGAAGAGTT
+TTTAAAATTTCTAGGCCACCTCTAGATGCACGTGGTGTCAGAGTGTCTCA
+TTTCGGTTTGATCTACGTGGATCTACAAAAAATGCGGGAGACGAGACGCA
+GAGTTCTCACCTGATTTTACATGGTTAAAAACGTGATGACGTCACATTTT
+TTGGGCAAAAAATGCCCGCATTTTTTGTAGATCAAACCGTAATGGGACAG
+CCTGACACTACGTGTACGTGCAGATGGCCTAGAAATGCTAAAATCTGTTT
+TTTAAATGTAACTTTGAAAGTGAAAGAAACAATTAGAAACAAGTTGGCTG
+TCGCCCCCAAAAAGTCTGTTCTGGCTATGTGGTCGCGAAAAGAGAAAACT
+CGGCCACCAATTTTTTTCCACGGCCAGATCTATGACGCTATGACGTCACA
+TTATCAGCTTGTTTCCGATTTACACACACATACACGTACACTTTCTCCGT
+ATCACTTTCACTGATAGCTTGAAACGAGATTAATCATCATTCCAGCTATT
+CTTTTTTATTTATTAGGTTAATGCCACTACTACTATTATTTTTTCATATT
+AAAAATACAATGAACTATGTAGACATAAATTCAAATGAGATGCCAAAAAG
+TGAGTTCGAACTTGTGGAAAATGTGTGTTTTTTAATAAATTTTTCAAAAA
+TATAGTAAATTTCTGAGAAATTTTGATTTGAATTCCCGCCAAGCATTTTT
+TTGAAAATTTTGAATTTCCGCCAACCATTTTTCCTTTTTTTTCAGAAAAT
+GTGAAAAAATTTTCTAAGCAAATTTGAATTCCCGCCAAGATTTTTTTTGA
+AAAAATTTCGAACTCGCGCTAAAGTATTTTCTAATAGCAGGATTATTGGA
+ATCCCCGCCAAAACATATTCTCAGAAAATTTGAATTTCCGCCAAAACTTT
+TTCTGATAAAATTTAAATTCCCGCCAACCATTTTTTCCTGAGAAAATTGG
+AAGAACATATTTTCAGTGAGAAAATTTGAAAATATTTTTTTCAGAAAGTT
+TGAATTCCTGCCAAAACATTTTCTAAGAAAATTTGAATTCCCGGCAAAAC
+TTTTTCTGATAATTTTTTGAAATTCCCCGCAAAAATTATAGTAAATGAAG
+ATGATTTGAGCAAAGTTATGACGTGGCCGCGGAAAAAATTGATGGCCTAG
+TTTTCTCTTTTCGCGGCCACGTAGCCAGAACAGACTTTTGGGACCGTACA
+ACCAACAAATATTTCTTCCCCTTTCAAAAATACATAAAAACCAGATTTTG
+ACATTTCTAGGCCATCTAGAGGTGCCTCGTGGCCTAGAAATTTGAAAAAC
+TCTTCCAGAAAATTTGTTCTGTATTTCTTGAAAGTGCTCCAACAAATCTG
+TGCAAATTTTAAAAACGTTTCAAAATATTTATTGAATAAATTCTTTTGTT
+GCACAAAGAGGTATCAAATCAGACCACCAGATTCGACCGTTGATCATTGT
+TTCAGTTGATAGGTAGGCAGGCGTGGTTGCCTGAAACCTGCCGGCCTCAC
+GCTGGGCAAGAGGCAGGCCGCCTTAATGTCAGGCAGGCAATGCCTACATG
+CAAGCCCTACTTCTACGATTATCTCGAAATTTAGCGAGTTTTTATTTGTC
+CAAAAAAAATCGCAACTGAACAACATGAAAAAGCCGCCAAAAACTTTCAT
+AAAATTCTGTCCGTAGTTTGCCGTTTCTTGCGTCTCATGCTTAATCCCTA
+CTGTAATTATGCTGAGATTTTCGATCTTTTTCACTTTTTGAAAATTTTTG
+GCAATTCTTTTTAAGTTTGTTGAGATTGTAACTTATGACAAACAGTAACT
+AAAAAGCGTGGCCGCCAAATTTTCTAGGCCATCAATATCAGTTGCGTCAT
+TTCTTCACCATACTGGACCGAGAAATATTCTAGGACATGTGTTTGCGTCA
+TTCCTCTTCCATTCCTAGTCCCAAAAATTCCAAGACCACTGGTAAGTTTG
+GCCGAGAAATATTCTAGGCCATCGATGTTAATGACGCCATTTCATACCCG
+AATTGGCCACTAAAATTCTTAGGTCATCAGTGACGTCACACCTCTTCCAA
+GCCTTGGAATGAGCATTTCTAGGCCCTCTAATCTAGGCTTGGCCGTCAAA
+TTTCCTAGGCCAGGTGACGCCATCCCTCTTCCATGCTCGACCACTAGGTC
+AAATGACGTCACTTCTCTTCCACCTACCGCACTTTGATTTCCTAGGCCAC
+CATGTGACGTCACTTCTCTTCCATCTAGGTTTCCCATGCCCTTCTCCTCT
+CACGTGGTATCAGAGTGTCTCATTTTGGCTTGAATACGTTGATCTACAAA
+AAATGCGGGAGAAGAGACGCAGAGTTCTCAACTGATTTCGCTTGGTTACG
+CACGTGCTGCCGTCACATGTTTTTGGGCAAAAAATTCCCGCATATTTTGT
+AGATCATACCGTAATGGGGTGTCCTCTTGTTAAATATCGAAATTTCACTC
+AAAAATTTTGAACGTTGAGCTTTTTGTCTCTGGTCAATTGGTCAGCCGCG
+CAGTGTTCCGGTGTTTGTGCTCATGTTTTCGTGTGCACATTTGTGCTGCT
+GCTAAGGCGTATTTTGTTCCGGGCGGGGACAGGGGGGAGAAGCAAAAATG
+TGTCAAATTTTGTTTGTTTTGCCATTGATATTGTCCTTCTGCTCAGAGGA
+TTTCCTCATTTTACGCCGTATGTGCAAAAGCATAATCACCACAATAATTT
+TGAATATAAGTTTGCAAACGCGCCCTATTGATAATCCTCGCCCGTGTAGT
+CTGCGTGCACGTGGTGTCAAAGTGTCCCATTTTGGTTTGATCTCCGAGAA
+ATGCGGGAGAAGAGGTGCAGACTTTTCAACTGATTTTGCATGGTTAAGAG
+TGTGCTGGCGTCACGTTTTTCTGGGGGCAAAAATTCCCGCATTTTTTGTA
+GATCAAATTGCAAAGCGCCCTATTGATAATCTTAGCCCGTGTAGTCTCTT
+GTTTAATTTTCAATTTTTCTGGTTCGGCACCTAAACTGTAACTACGACAC
+TCGGCAAAGTTAGACTGTTAAACTCCGCCCACTTAATGGCACCTTTTTTG
+CAGAAATGTACCCAACCGACAAAGAGCAGACACGGACCACATTTGAGACG
+AGAAGTCGGCGGAAACGGCTGGCGCAGGTCGCCGCCACAATTGCTAGCGT
+GATATTACTCTTGTTGGCAGGTAAGTAAAAAACTACGACACTCCGAGACC
+AAGAAAAAAATCGATAATCGAAATATTGAAAATTGCAAAATTTATTTCGC
+CGGATCATTTTCCATATCGATTTTCTGAATGGTATGGTGATAGCAATCCT
+CATCGTAGGCACATCCCTGGTGAACCACGTACTCTTGACCTGAAAAATAG
+GTTTCGTTCGGTGGAGCACATTTGCATACACTGACCTTTAATCGGGTGGC
+GACACGCTTTACACTTGAAACATGCCATATGCCAGTGGACATTGAACGCC
+GACACGCATCTCTCAAAAGTCGGCAATTTGCACGCGTGGCATTTTGGTGA
+CTTGGCCGCCCGGTGACAGTCCGCGCAACGGAGCGCGTTACCGTACGGCG
+CGGGCATTGGATAACACGGAGTCATGCCAATGACTGTCTGGAATTTTGGA
+GAAATTTATTGATTTTTTGACGGAATTTAATGAAATAAGGAAAAATCAAT
+AATCGACATATTTATTTCGCAAAAAAAAAAAAACATTATTGATTTTCACG
+GATTTCTGTCTTCCTCATAAATTGAAATGGAAGAGTTTGCCAAACTAGGC
+CATTTTGGCTCGGCCATATCTGGGGTAGATTTACGGTGCGTTGCGTGTCG
+CGTCGCGGCTCGGTTTTTGTAGTAAAACTAAATGTATTTGTCCGTGCATG
+GAATTCTGGCTTCCCTCATAAATCGAAATGGCAGAGTTTGCCGAACTAGG
+CCATTTTGGGTCGGAGAGATTTTGTGTAGATTTACGGCGCGTTGCGTGTC
+GCGTCGCGGCTCGTTTTCAATTGTAAAACTGCTGTATTTGTCCGTGTGGC
+GTACACAACACTTTTCCACGCGCTGTCCGGCAGGCAATTGTCAGTGGAGC
+GCAAAAATTTAATTAGGAAGGCCAGAACCCCGTGTCCGTGTGGAGTGCAC
+GACTTTCCCGCGCGTTGTCCGGCGGGCGATTGTCAATGGAGCGCGAAAAA
+TTCAATGAGGAATGCTTTTTGCAAAAACAAATTACATAGGCTTCTGGCCT
+TCCTTATTGCATTTTTCGCGCTCCATTGACAATCGCCTTAAAGCAGGGGA
+GTGTGTGTGTGTGTACTCCACACGGACAACTTAAAATGAAAACCGAGCCG
+CGACGCGACACGCAACGCGCCGTAAATCTACTCCGGCCGTGGCCGAGTCA
+AAATGGCTTAATTCGGCAAATTCTTACATTTCAAAATATGAGGGAAGCCA
+GAAACGTGTGTCACATGTTATAAAATTAATTTTGAAAAAAAATTATTAAA
+TTTCGCAAAAATAAATTATCGCTTTTTGTAAGAATTTATCGAATGAATTG
+ATTAAAAATTTATCGAATTTTAGCGAATCAGAAAATATCGATTTTCACTA
+AGAATTTATCGAATTTTTCGATTTTCGCTAAAATTATCGATTATTGCAAT
+GTTTTACCTGACAAACCGAGCATTTCAGGCATGAAATATGATACATCTCG
+TCTTGAATTTTGATCACTTTTCCCTGCAAAAATCGATATTTTCAATTGAA
+TATATTTCCAAAAATGTGCTCACAGTTTGAGCTTCTTGACGAGTCAGCGT
+TGTTGTGCAGCCTTTGCAATGGATATTATATGGAAGAACAATCTTTTGGA
+GACGTTTATTGTTCGACGAGAACAACATTTTTCGAATTTTTGAAATGATT
+AATTTAAAAATTTAAAAAGGAGAAAATTGAAGAGAAACGTGGGAAAACGT
+ATTGATTTTTCAAAATTTTATTGATTTTATAATCACGGGGTTCTGGTCTT
+CCTCATTGAACTTTTCGCGCTCCATTGACAATCGCCTTCCGGACAACACG
+TGGGAAAGTCGTGCACTCCACACGGATAAATACATTTAGTTTTACAACTA
+AAATCGAGCCGCGACGCGACACGCAACGCGCCGTAAATTTACCCCAGATA
+TGGCCGAGCCAAAATGGCCTAGTTCGGCAAACTCTTCCATATGAGGGAAG
+CCATAAATCCGTGTATAATCAAACGCGCAATTTAAAAAAATCGGTAGTTG
+AAATTTATCGATTTTCCCTCGATCTTATCGATTTTTTAAAAGACTTATCG
+ATTTTTATCCAAATTTATTATTTGAAAAATCAACGTTTATTGATTTTTGT
+CATGATTTATCGATTTTCTCAAGAGATTATCGATTTTTGCTGTCGATGCA
+CCATGTGCAAACTTCGCCACGTTTTTTCGCGGCGAGACCCAAATTTTTTG
+AATTTTCAGTTCTCGGTCTGGTATACGGTAGCTTCTACCTCTACCGTCGA
+TATGTGACAGATGCAAATGATAAACGGGATAATGATGAATATTTGCGAAA
+ACTCGTTCGTCAAGTCAATGACTCGCCGGAGACCACGTGGAAAGCCAAAT
+TCAATAAGTTTGGTGTCAAAAATCGATCTTACGGATTCAAATATACGAGA
+AATCAGACGGCGGTCGAGGAATACGTGGAACAAATTCGAAAATTTTTCGA
+GTCTGATGCGATGAAGCGGCATTTGGAGTGAGTTAACTCAAATTTGAGCG
+GGAAACAACGATGCTCCGCGCTCTCGCCGCATGTAGTTTAGCGCGTAAGC
+TGTGATGCATACGATAGTCCTGCAATGCATCATATTTTACACGCAAATGC
+AGAAATTACCAAATTTCGAGAAAAATCTATATTTTCCTTTTAAAAATTAT
+CGATTTTTTAAACAAAACTTCTGAATAATTGGATTTTTCCAGAAGTTTTA
+AAAAGTTTTGGGTACAATTTTAAAAAGACAGCAAAATGTTCGTAAAACAC
+CAGGAAAGAATTTTGCGCTTAATATCTGATGCTTCGTAAACTCCACGGGC
+TTCCGGCCTTAAAGCCGAGCTACGCGCCGTAAATCTACCCCGGCCGCAAC
+GCGCCGTAAATCTACCCCGGCCGTGGCCGAGCTCAAGTGGCCTAGTTCGG
+CAAAATCTTCCATTTCAAAATATGAGTGAAGCCAGAGGCGCGTGAATGAT
+GACTTCCACACGGTTCGGTAGAGCGCATTTACACTTATGTACCCTTTGCC
+GGGCTGCGTTCAAAACCTAAAAATTTGAAATTTTGCGCGTAAGATCTGGT
+GCATTGGGTTCTGAATTATTTCGACAAAACATGGTGCATCATCCCAAAAA
+TTGCAATTTTGCAGTGAACTTGAGAACTTTAACAGCTCCGATGTTCCGAA
+AAACTTCGACGCTCGTCAGAAATGGCCGAATTGCCCGTCAATCTCGAATG
+TTCCAAATCAGGGAGGATGCGGGAGTTGCTTCGCGGTCGCCGCCGCCGGT
+GTCGCCTCCGACCGTGCCTGTATTCACTCGAATGGAACTTTTAAGTCACT
+TTTGTCCGAGGAGGATATTATTGGATGCTGCTCGGTGTGCGGAAATTGTT
+ACGGCGGAGATCCACTGAAGGCCTTGACCTATTGGGTTAATCAGGGACTT
+GTTACAGGTAAGCGGTGACGTCATAGGTGGCCTAGGAACCTTTGATCTAC
+AATGTGATTGAATTTTATATCACGCAATTTGTAATAATTTCTAAAAAAAA
+TTATCGATTTTTCTGAAAATTAACTTGTTCCAAATTTTGAACGAATTTTC
+TAGAAGATTTTTGCAATTTATCGATTTTTGCAAGCTATCGATTTTTCCCG
+CAAACTATCGATTTTTCTAGAAAATTATCGATTTTTCTAGAAAATTATTG
+ATTTTTCTAGAAAATTAACGATTTTTCTAGAAAATTTTCGATTTTTCTAA
+AAAAAATTATCGACTTTTTTCTCAAAAGTATCGATTTTTGCAATTTATCG
+ATTTTTTGAAATTTATCGATTTTCCCTGCAAATTATCGACTTTTTTGAAA
+ATAAGCTTTCCCCAAAAATTTGAACGAATTTTCTAGAAATTATCAACTTT
+TGCAATTTATCGATTTTTTTTTTGCAATTTATCGATTTTTTGCAAATTAT
+CGATTTTTTGCAAATTATCGATTTTTCCAAACAATAACGATTCTTCTAAG
+CCCGTGGAAGAGTTTTTCGAAAACCTAGGCCATCTCTATTTCCAGGTGGC
+CGTGACGGTTGCCGTCCCTACTCGTTTGACCTGTCGTGTGGAGTCCCGTG
+CTCGCCGGCCACGTTCTTTGAGGCCGAGGAGAAGCGAACATGTATGAAGA
+GGTGTCAGAATATCTATTACCAGCAGAAATATGAGGAGGATAAACATTTT
+GGTTAGAGATATTTTTTTTTAGAAAAATAGAGAAAAATTTCTGGGATCTA
+TTCAAAAATGGCAAACTTTTTGGAAATTATCGATTTTTTCCGGTAAATAA
+TTATCAATTTTTTTCTCGGAAAATATCGATTTTTTCGGAAATTGACAATT
+TTTTCGAAAATTATCGATTTTTTCCGTTAATGATCGATTTATTCGGAAAT
+TATTGATTTTTCCGATAATTATCGATTTTTCGGATAATTATCGATTTTTT
+CCGATAATTATCGATTTTCCGGTAATTATCGATTTTTTCCGATAATTATC
+GATTTTTCGGATAATTATCGATTTTTTCCGATAATTATCGATTTTCCCGA
+TAATTATCGATTTTTCCGGTAATTATCGATTTTTTCCGATAATTATCGAT
+TTTTCCGATAATAATCGACTTTTCCGATAGTTATCGATTTTTCCGATAAT
+TATCGATTTTTTTTCGATAATTATCGACTTTTCGGGTAATTATCGATTTT
+CCCGATAATTATCGATTTTTCCGGTAATTATCGATTTTTTCCGATAATTA
+TCGATTTTTCCGATAATAATCGACTTTTCCGATAGTTATCGATTTTTCCG
+ATAATTATCGATTTTTTTCGATAATTATCGACTTTTCGGGTAATTATCGA
+TTTTTTTCCGGAAATCATGAATTTTTCCAATAATTATCAATTTTTTCCGA
+TAATTATCAATTTTTCCGATAATTATCGATTTTTCGGATAATTATCGATT
+TTTTCCGATAATTATCGATTTTCCCGATAATTATCGATTTTTCCGGTAAT
+TATCGATTTTTTCCGATAATTATCGATTTTTCCGATAATAATCGACTTTT
+CCGATAGTTATCGATTTTTCCGATAATTATCGATTTTTTTTCGATAATTA
+TCGACTTTTCGGGTAATTATCGATTTTCCCGATAATTATCGATTTTTCCG
+GTAATTATCGATTTTTTCCGATAATTATCGATTTTTCCGATAATAATCGA
+CTTTTCCGATAGTTATCGATTTTTCCGATAATTATCGATTTTTTTCGATA
+ATTATCGACTTTTCGGGTAATTATCGATTTTTTCCGATAATTATCGATTT
+TTCCGATAATAATCGACTTTTCCGATAGTTATCGATTTTTCCGATAATTA
+TCGATTTTTTTTCGATAATTATCGACTTTTCGGGTAATTATCGATTTTCC
+CGATAATTATCGATTTTTCCGGTAATTATCGATTTTTTCCGATAATTATC
+GATTTTTCCGATAATAATCGACTTTTCCGATAGTTATCGATTTTTCCGAT
+AATTATCGATTTTTTTCGATAATTATCGACTTTTCGGGTAATTATCGATT
+TTTTTCCGGAAATCATGAATTTTTCCAATAATTATCAATTTTTTCCGATA
+ATTATCAATTTTTCCGATAATTATCGATTTTTCGGATAATTATCGATTTT
+TTCCGATAATTATCGATTTTCCCGATAATTATCGATTTTTCCGGTAATTA
+TCGATTTTTTCCGATAATTATCGATTTTTCCGATAATAATCGACTTTTCC
+GATAGTTATCGATTTTTCCGATAATTATCGATTTTTTTTCGATAATTATC
+GACTTTTCGGGTAATTATCGATTTTCCCGATAATTATCGATTTTTCCGGT
+AATTATCGATTTTTTCCGATAATTATCGATTTTTCCGATAATAATCGACT
+TTTCCGATAGTTATCGATTTTTCCGATAATTATCGATTTTTTTCGATAAT
+TATCGACTTTTCGGGTAATTATCGATTTTTTTCCGGAAATCATGAATTTT
+TCCAATAATTATCAATTTTTTCCGATAATTATCAATTTTTCCGATAATTA
+TCGTTTTTCCCGATAATTATCGATTTTTCCGATAATTATCGATTTTTCGG
+ATAATTATCGATTTTTCCGATAATTATCGATTTTTCCGATAATTATCGAT
+TTTTCCGATATTTTTTTTCGGAAATGGCTGCCCCATCGCGGTTTGATCTA
+CAAAAAATGCGGGAATTTTTAGCCCAAAAACATGTGACGTCAGCACGTTC
+TTAACCATACGAAATCAGTTGAGAACTCTGCCGCATTTTTTGTAGATCTA
+CGTAGATCAAGCCGCAATGAGACACTCTGGCACCAAGTGTCTGTAATTGA
+CTTCACGGAAGAAAATATATTTTTATTTAATGCGCAAAACTAAAATTCAA
+AATTTCGTTTCGACCAATACACCATATTTTAAGCGCAAATTTCAATTCAA
+ATTTTTGCAGCAACCTTTGCCTATTCAATGTATCCCCGCTCAATGACAGT
+ATCCCCCGATGGAAAGGAACGAGTAAAGGTGCCAACAATCATCGGTCACT
+TCAACGATAAGAAAACCGAGAAGCTGAACGTGACCGAGTACCGTGACATC
+ATCAAAAAAGAAATTCTACTTTATGGTCCCACCACGATGGCGTTCCCAGT
+TCCCGAAGAATTCCTTCATTATTCGAGCGGAGTGTTCCGCCCGTATCCAA
+CTGATGGTTTCGACGATCGAATTGTGTATTGGCACGTGGTTCGATTGATC
+GGATGGGGAGAATCAGATGATGGAACACATTATTGGTTGGCTGTTAATAG
+TTTTGGTAACCATTGGGGTGATAATGGTGAGTTTTCGTGCAAATTGCGCA
+CGGCCCGGCAAATGGTACATCCATACAAATGCGCTCCACTGATAATTTGA
+GTTTAGCCAGGTTTGGGCGCGTTTTAAGGAAAACGCCTTGGTCCAAAAAA
+TTTAGAATTTGATTTCGGACATTTTTTATATGCATCACAAAAATGTTGGA
+CGAGCCGTTTTTGAGAAAAAGCCCAGGTATACGGTAAACAAATTGCGTAC
+AGGTGCCACTTCCCGGGCCGTGATGCGCGTTAAATATAGTGCTTTTTAAG
+AATGCGTGTTGCGCAACATATTTGACGCGCAAAATATCTCGTAGCGAAAA
+CTACAGTAATTTTTCAAATGACTACTGCAGCGTTTATGTCGATTTACGGG
+CTCGAAAAAAAAGTTACAGCGATATTCCATTTTTTCTCATTTTTTGCTTA
+TTTTTATTTAGTATTCTCACGGTGTGTCATTCTGTCCCATAACGGTTTGA
+TCTACAAAAAATGCGGGAATTTTTCGCCCAGAAAAATGTGACGTCAGCAC
+GCCCCTAACCATACGAAATTTGTTGAGAAATCTGCGTATAAATTCCCGCA
+TTTTTTGTAGATCACGCCGAAGTGAGACACTTTGACACCACGTGTATTCT
+ATCTAAAAATAAATTATTTCAAAAATAGAGCCCGAAAAAAAAAATCGACA
+AAAGCGCTACAGTAGTCATTTAAAGAATTACTGTAGTTTTCGCTACGAGA
+TATATTGATATTTTGCGCGTCAAATATGTTGCGCAGTACGCATTCTTAGA
+ATTTTGTGTTGCCGTAAATAAATTTGGACGTCAAATACAGTGCATATTGC
+GGTCGATCGGCTACAATATATTTTGCGAGCAAATTTGGAAGTTTTGCGCG
+TCAAATATGATGTAGCCGATCGGTCATGTTACAAAACACCATATTTGACG
+CGCAAAACTTTAATTTTGGACAAAAAGTCAGAGAATTAGTATTGCGTAAA
+AAACTGGCAATTTTTTTCAGAACATTTCTGAAATTTTCAATATATTTTCA
+AACTTTTCGCGTCAAATATGGTGCATCAAGTCGCGAACCAAATACACTCT
+AACACGTAGTGCCAGGCTGTCCCATTATAGTTTGACCTACAAAAACGCGG
+GAATTTTTCGCCCAAAAAAATGTGACGTCAGCACGTTCTTAACCATGCAA
+AATCAGTTGAGAACTCTGCGTCTCCTCTTCTCCCGCATTTTTTGTAGATC
+AACGTGATTCAGGCCGAAATGTGACACTCTGACACCACGTGGCCCTAATT
+AACTCGTAAAAATCACCGTTTTTTTTCCAGGACTCTTCAAAATCAACACA
+GATGACATGGAAAAATATGGTCTAGAGTATGAAACAGCAGTCGTCTAATT
+ATAATTCGGCAAAAATTTTTTGTAAATAGTTAAATATTGTCCACCTATTT
+CATCCCCACCCGATTGCATCTCAACTTGTCCCATTTCCGAGAAAAATCAA
+TTATTTATTTTTATTCGGCCATCATTTATTAGCTCCCTCATTCCATAGTT
+TTTTTTTAATTAGATTTTTTTTGGATGCTAAAATTTGCCATTCTCATAGA
+CATTTTCAATATTTGTGTAAAATAAATCATTTTTCTGGTCTTCAATTGAT
+GGAAAAAAACAAAAAAACAATGCGCGTCAGGTTTGGTGTATTGTGTGCAA
+ACACCGAGCGCATATTTTGAAATTTATTTTTTTTTCGAATTTATTAAAGT
+TGCTGATTTTCTTTAATTTCAGGCTTAAAAATGTCGGATTTTGTGCCAGA
+AACCGAGGAAAATGAAGAAGAATCTCAAAAAATCGATGAAATCCATGAAA
+TCCCAGCTCAAGCAATTATCATCGACCAAAGTGAGGAAAATGCTGACTTT
+ATCAATTTTCAATTACTTTTTGCATTTTTTCTAGGTTTTTCTCGACGATT
+TCTCAACAATAAATGGTACGGAAAGTACGGCGAAGATGGGGATCTTCTGG
+AGCACATCGACGAGGACTGGGAGCCCGTAGGCCTCGACGAAGTGGAATTT
+CTGAGCCAACTGTGGTTTGAGCAGGAGGATCAGGAGAAAAAAGCTCATAG
+GCACTATGATTGGGATGAAGAAAAGAAGGAATGGGTGCCGAAGGCCAAGC
+AGGAGGAGGTCAATGAGGATTTTATCGCAGAATATCAAGCGAATTACGGG
+GTTCAGTATGATGATATTTATAAAAAAATGGACGAAGAATTGCAAGAAAA
+AGCGGCAAAAGCTCAAAAAGAAGATGAAGAGAAGAAGGAGAAGAAGCGGA
+AGAAAAAAGTTGGCTTGGGAGCCGGGGAAGACGCTAAAGAGGGCTGGCTT
+GACCTAGGAGATAAGGTTCATGCGGTTTATGTGTCAAATCTTCCGGAAGA
+TATTACAGACGAGGAATTCCAGAAATTTATGTCAAAATGTGGAGTTATTC
+AGCCGGATATTCGAACGAATAAGCCGAAATGCAAGCTTTACCGGGAGGAA
+AACGGCAAACTCAAAGGCGACGGAAGATGTTGTTATATTAAGAAGGAATC
+TGTCGAGCTTGCCTGTAACATTCTCGATGGAGCGAACTTAAACGGGCGGG
+AAGTGAAGGTTGAGGAAGCTCGATTTGAGATGAAGGGCGATTTTGATCCG
+GCGAGGAAGCGGCGGAAATTGACTGCGGCGCAGAAAAAACGATATATGGA
+GCAGCAGAATAAGTAATAAAAAATATTTGGTGAAATTTGAAATAGCTCGT
+AAATCGACATTAAGCTGAAAAAATGAAAAAAAACCAAAAAAAATCGTATT
+ACGGGAACACAAAATCCTGAGAATGCGTACTGCACAACATTTTTTTTTTT
+TTTGACGCGCAAAATATCTCGTAGCGAAAACTAAGACTACTGTAGCACTT
+GTGTCGATTTACGGGCTGCTCGATTTTCGAAATGAATTAAAAGAATTTAT
+TTATGTGATATTGAAATTGGGCAAAAAATAGGAAAATAATACAAAAAAAT
+CTAAAAAATTTATTTCAATAATCGAGCCCCCGTAAATCGACACAAGCGCT
+ACAGTAGTCATTTAAAGAGTAGTTTTCGCTACGAGATATTTTGCGCGTCA
+AATATGTTGTGCAATACGCATTCTCAGAATATTGTGTTCCCATAATATAT
+CGACGAAAAAATTGGCCCAAATCGTGGATTTTTGTCCGAATTTGATGACA
+AATGGCTTTGAAAATCACAAAATTTCAGAGAAAAATTTCGATTTTTGGTT
+TAAAAAAACAAAAATTGAAACCCAACAAAATTGTTAACTTGAAAACCTGC
+TGAAAATCTTAGAATTTTCAGATTTCACCCAAAAAATACCAGATTTAACT
+CGAAAATTGCGAATTTTAGGCCAAATTCCTTGCATTTTTCATAGAAAAGA
+TAAACTAACGACACAAAATCAAATGAAATTGACTAAAAAACTATTGAATT
+TTGTAGAAAAATCCCGATTTTTGCCTAAATTTGCAAAAAAAATATTTTAT
+TTTAGCATTTATTTTTCTTAATTTTCACACTAAAAATTACGAAAAAAGAC
+AAAAAAAATTTTTTTCATTCAACAATTTTTTGGGCTAAAATGTGTAATTT
+TTGCGGGAAGAATTCGAAAAATTATTAAAAATCGTAGAGACTAACTGAAA
+ATCAATTTTTTAGGGACCAAAAAGCCAACTTTTGCCGATTTTACTCAAAT
+TTTTCCGTGAAAAATCCGGAATTTTTAAATATTATTTAATTGCGAAATTT
+TACAATTTTTACACCTAAAATAAGGGTAATATGGTAGCTGGTCTCGACAC
+GACAATTTTTTTGTTAAATTCTAAAAAAGGTGTGCGCCTTTAAAGAGTAC
+TGTAATTTCAAACTTTATGGAATTTTTTTTTGATTTTTCAAATAAACTAC
+GAAAAATCGAAGAAAATTCCACAAAGTTTGAAATTACAGTACTATTTAAA
+GGCGCATACCTTCTAGAATTTTACAAAAAATTTGTCGTGTCGTGACCGGC
+GACCGTATTACCCTAATTTTTGGTGTAAAAATCGTAAACTGTCCGGATTT
+TTCACTACGAAATTCAAATTCGAGGAAAATCGAAAAAAATTGGTTGTTTT
+GGTTCCTAAAAAATATATTTTCAGTTATTTTCTACCATTTTTTAATAATT
+TCTCGAATTTTTCCCTCAAAAATTACAAATTTCAACCAAAAATTCTGATT
+TTTCCTTTCCAGAATCTTCGAATGGACGCCCGATAAGCCACGTAACTACC
+GTCCAAAGTCGGACTGTACGGTTATTGTCAAAAATCTGTTCACTCAGGAA
+ATGATGAACAAGAATGCGGCGTTGATGTTGGATTTGAAAGAGGAAATGAC
+ACAAAGTTGTCAGAAATATGGAATTGTTAAGAAAGTCGTCGTTTATGCGG
+TTGGTATTGAGGAAATTTGTGGAAATTTCGATTTTTGTAAAAAAAATTTA
+TTCTAAAAAAATAAATTAAAAAAAAAAGATTTAAAAAATTTAAAGCTAAT
+TTTCGAAAAATTGAAGCTAATTTTGGAAAAAAAACCGAAAATTTTTTTTT
+TTAGAAATGTCGATATTCATAAAAAAATATTCTAAAAACGGGATCAAAAA
+TTTTTGAAGCTATTTGTCGGAAAAATTTTTAAAAATGTAAAGCTAATTTT
+CGAAAAAAAACCCAAAATTATTGGATTTAACAAATTTTCAAAAAAATTGT
+TCTAAAAAAGATAACCTTTAACATTAAAAAAATTATGGCTATTTTTCGAA
+AAATTAAAAAAAAACAATTTTTAGCTAATTTTCGAAAAAAAACCGAAAAT
+TTGTGGAAATTTCGATTTTCAAAAAAAATTTATTCTAAAAAAAAATAAAT
+TTTTAACATTAAAAAATGGCTATTTTTCGAAAAAACCGAAAATTTTTGGA
+AATTTCGATTTTCGAAAAAAAAGTATTTTAAAAAAACAATGAGAAATGGT
+TATAAATTGTTCTTTCAAAAATTTTTTACAGCTTTTTTTTTCGAGAAATT
+TAAAAAAAAAACAATTTTTAGCTAATTTTAAAAAAAGTAAAGCTAATTTT
+CAAAAAGAACCCCAAAATTGATGCATTTATCGATTTTTAAAATAAATTGT
+TCAAAAAAAGATAAATTTAAAAAAAAAGTTATTGGATTTTTTAAAGTTAT
+TGGATTTTTCAATTTTCAAAAAAAAATCATCAAAATGTATAAATAAATAA
+AAACTATGGATTTCGAAAAATTAAAAAAAACAATTTTTAGCTAATTTACG
+GAATTAAAACAACAAAAAATTTCGGAAAATCGAAAATTGTTGGTTTTTTT
+TTTCGATTAAAAAAATTCAAAATCTTCTGAAAGACATTTTTAAAATTTCC
+AAAAAAAAATTATGAGTATTTTTCAAAAAACAAATCGAATTTTGATTAAC
+TTCCGATTTTTTTGACATTTTTTGAAATTTGAAAATCATTAATTCAAAAA
+TTTTTATTGAAATAATTCAAAAATTTTTATTGAAAAAAAACGAAAATTTT
+TGATTTTCGCTTGAATATTTCGGAAAAAACAATCGATTAAAAAAAAAATA
+GGCTTCTAGTTATTTTTCAAGAATGCTTTTTTTTTGACAAACTGCTGATT
+TTTTGTCAGTTTCGTCGATTTTCGTTGTAAAAAATCAAAAATTCAAAATT
+TCTTCTATTACGAGTGCACAAAATGCTGAGAATGCGTATTGCACAACATA
+TTTGACGCGCAAAATATCTCGTAGTGAAAACTACAGTAATTCTTTAAGTG
+TCTACTGTAGCGTTTTCGGAAAAATTCCACTTTTTTTATTTAAAAAAAAA
+AACGAAATATTTTGATTTTTTTTTATTAAAAAAAACGAAAAATTTTGATT
+TTTTATTAAAAAAAACGAAATATTTTGATTTTTTATTTAAAAATGAAAAA
+TTTTGATTTTCCAAAAAAAAAGGCTCCTAATTAAAAAAAAAAAATTTTTT
+TGAAAAAGTGCAGATTTTTGTCTTAAAATTTAAATCAAAAATTTTTAAAT
+AGACTTTTTCCATCAAATTTCCCCAATTTTCAGAACCACCCGGACGGCGT
+CGTATCGGTAACCTTTCCAACGACAGAAGAATCGGATATGGCTGTAAAAT
+ATCTTCACGGACGAGTAGTTGACGGTCGGAAATTGACAGCCGAGCTCTGG
+GATGGCCGGACAAAGTTTAAGGTCGAGGAGACGGAAGAGGATGAGGAGAA
+GCGTCGGAAAGAGTACGAGAAGTATATTGAGGGTGGAAGTAGTGAGACGA
+AGGAGGAGAGCGACGACGATGATGACGATGAAGCTGAAGATAATTGATTG
+ATCTAAATTTTTTCTGAAAAATTATTTTTAGTTTATACATTTTTCCGAGA
+GGAGCAACCGATCAATTTTTACCAAAACTATGTTCAAAATCGCCCAAAAA
+TATCAAATTTAGTGAATTTTCGTTTTCATGGATTTTTCGAAAATTAGCTT
+TAAAAATGTTTGCCAAATTTTTCGACGATATCGCGATATTTTAAAAATTT
+CGAACAAAAATTGCCTAATTTCAATTAAAATCCCTTTTTTCGAAATTTTC
+TAATTTTCTGGGCCAATTGGGTCGTTTAAAAAGAAAAATGGCCAAAATTT
+GAGAGTTTTAAAAAAATTCTAAAATTTCAATCCTACGATTTTCCGGGAAA
+AAAATTTTCTTGGAAAATTGCTTTTTTTTTGAAAAATTATTTTTAGTTTA
+TACATTTTTTTTCCGAAAATAGGAACAACCTATCAATTGAAATTTTCAAA
+AAAAAATTAATTAAATTTGGAAGCATTTTCCGAAAAATTGCATGTTTTCG
+GTTTTCTAGAAAAAAAAAACTAAAAGAACGAAAAATTTCACCAAAAATCA
+AATATGAAAATACTTTCCTAAAAATCTGAAAAAACCAGAAATTTTCAATT
+TTCCCTATTCAAAAAAATTCAAAAAAAAAACCAAATTTCAGTTAAAATCC
+CTTTTTTCGAAAATTTTAAAATTTTCTGCGCCATTGTGTCGTTGATTTGA
+AATTTTTTTCTAAAAATCCGTGAATTTTTGAAATTAAACAAAAAATTTGA
+AAAATCAAAAATTATCGATTTTTCAACGAAAAAAATTCAAAAATTTCAAT
+CTTACGATTTTCCTAACTAAAAAAAAATTTGAAGTAACGAAAATGTTCAA
+TTTTTTCGAAAATTTTCGAGGTCATTTAGAGTTTTTTCTGTGAAAATTGC
+ATTTTATATACTCATTTAAATTAATTTTTATATATTCCTTTCCCGAAAAC
+TTCAAAAAAAAAACCCAGTGATACAATTAAAATCGAGATAATCACAGACA
+AAGTAGGCAGTAGGCAGGCAAAAAACAGGCACATATTAAGGTAATACAAA
+ATTCTGATAATGCGTACATCGCAACACATTTGACGCGCAAAATATCTCGT
+AGCGAAAACTACAGTAATTCGTTAAATGGATACTGTAGCGCGCTAGTGTC
+GATTTACGGGAATCTTAAAGAACCTAAAGAATTGTAGGAAAAATGGAGAT
+CCCGTAAATCGACACTAGCACGCTACAGTATCCATTTAAAGAATTACTGT
+AGTTTTCGCTACGAGATATTTTGCGCGTCAAATATGTTGTTCAATACGCA
+ATTTTAAAATTTCGTGGTCTCATAATAATACACAATTAACTAGTAAATCT
+ACAAAATCTACAAAATTCTCTTCATCAACTCTTCCACAGCTCGATCGACC
+TGTGCATGAGTCTCCTCGTACGCCCACAGAGAGCACAACGCCACGTTGCT
+ATTGTCGAGACGTTCCTTATTCGAAATCTGTGACGACATGCGATCCTTGG
+CCTGATCTTCAGTCAGGTTATCCCTCGCAACGACTCGACGGACGGCTTCA
+TCTGCTGGCACGAAGACGGTCCACGTTTCGGCGAGCGTTTTGTGCCATCC
+GGCTTCGATTAGTGCGGCCGCTTCGATGACTGAATGAATTTTTTTTTCAA
+CTTTTGCAGAAAAAATTATGATTTTGCAAAATTAACGGGGAAAATTGGCT
+GTTTAAAAAATATTTATTATTTTCGCGTTTTTTTAAAATAAAAATCGATG
+AAAATTCTGCAAAGTTTGAAGCTTCAGTACCCTTCAAAGGTGCACACGTT
+TTAGAATTTAGCAAAAAATTGGCGTGTTCACGATTTTTTGGTTAAATTCA
+AGAAAGTGTGCGCCTTTAAGGAGTACTGTAATTTCAAACTTGCTGAATTT
+TCATCGATTTTTCACTTTTTTTCCACGATTAGTAAAATTTGTGTTATTGT
+AGATTTTTTAAATTTAATACCAAATTTTCCAAAAAATCGAAAAAAAAAAG
+AAAAAATGTAATTTCGTTATTTTCAAAAAAATAAATTGAAAAATTGAAAA
+AAAATCCAAATATTCGATTATATTTTTTCAGAAAATAAAAATGAAAATTG
+GAAAAAAACATATTTTTGGGTTTTTCGATTTTCCAAAAAATTTAAACATT
+TAAAAAATCTAAATTTTCGATTTTTTTCAAAAAAAAAAAATTAAAAATCG
+CACAAAAACCAAAAAAAAACATTTTTGGCCGATTTTCCAAAAAAAAAAAG
+AAAAATAAACAAAAAACAAATATTTCAAAAAAAAAAACAATTTTTTCCGA
+TTTTCCAGAAAAACAACTGAAAATCGGAACAATAATTTGTTTTTTCTATT
+TTTCAAAAAATATTGAAAAATAAAAGAAAAAACGGAAATTTTCGATTTTT
+TTCCGATTTTCCAAAAAAAAAAAATTCAAAATCTCACAAAAACCAAAAAA
+AAAATGAAAAATCAAAGAAAAACGAAAATTTCGTTATTTTCAAAAAAATA
+TCGAAAAAACTTTTTTTTCTTCCGATTTTTCTGAAAAACACTGAAAATTG
+TGGAACAATAATTTTTTTCTATTTTTTTGGTCTCCACGATTTTTCGCGAA
+AAATTTCAAAAATTAAAATTTTTTTTTAAATCCAAATTTTCACTTCCCCC
+CCCCCCCCCCCCTCACCAACAACTTTCGCCGTCGACTTCTTCACAATCTC
+CATAGCTTTCTCTTTCACCTCCGGCCAAACAAGCTCACTCAGCTCGCGGA
+GCTTCACCTTATCCGAAAACACAATCGTTCCAAGCTTCCGGCGGTCTACA
+ACTCCATCGACAACGACATCCCCTCCAAAATGTTCGCCGATTTTTCGATT
+CAACGAGCTTCCCCGTTCATAGCACGTGTGTGCGAGCTTATCACAATCGA
+TAACATCGAAATTATGCGTTTCACGGAGATATTTCCCGATATGACTTTTT
+CCCGACGCAATTCCTCCGGCGAGCCCAATGATGTACGGGGCGCCCGTTTC
+TCTTGGAACCGCCCGAGCTGGACGGAGCAAGTGACCCAGATCCTCTCGTC
+GTCTGGAGCTTGAGCTGATCTTTGTCTCTTTCAGGATCTCATCGGATCCT
+TCCACCAGCTCGACAATTATCACATCCAGCTGCGACATTCCTTGCTCATT
+TCTCTTTTTGTTCACCGCATCGGCACCTTTAATGGTCTCCCGGGACACTA
+CTATCGCTTCGAGGTCTTTTATTCGTGTTGAAGGACCGAATGGGTCGATT
+ATTGGCTCCGCGAGACATTTTGCCTGGAAAATTATGGGGGTTCTATTGAG
+CAAAAATGACCATTTTTGGAAAATTAGAAAATCGGAAAAAAAAATTTCCC
+GAAATTTTTTATTTAGAAAAGTTTTTAAAAAACAGAAATTATATATTTTT
+TGAGTTTTCCAAAACAAAAAATCGAAAAAAAATATTTCGATTTTTCGGAT
+TTTCCAAAAGAAAAAATTTAAAATATCGAAGTTTTTAGATTTGCAATAGA
+AAAATTGAAAAAAAAAACGGAAATTGTATTACGGGAACAGAAAATTCTGA
+GAATGCGTATTGTACAGCATATTTGACGCGCAAAATATCTCGTAGCGAAA
+ACTACAGTAATTCTTTAAATGACTACTGTATCGATCAAGCCCGTAAAGCG
+CTACAGTAGTAATTTAAAGAATAACTGTAGTTTTCGCTACGAGATATTTT
+GCGCGTCAAATATGTTGTGCAATACGCATTCTCAGAATTTTGTGTTGCCT
+TAATGCAATTTCCGTTTTTTTTTCAATTTTTTCTTTTGAAAATCTGAAAA
+TTTCGATTTTTTCCAATATTTTCTTTTGGAAAATCCGAAAAATCGAAACA
+AAAATTTTTTTCTATTTTTTAAATTTTTTTTTTTGGAAAATCGGAAAAAA
+ACCAAAATTTTAGTTTTTTAAAATATTTTATGGACCAAAAATATCGATTT
+TTCCTAAAGTTTTATAGAAAACTGAAAAATTTAAATATTTATTGTTTTTA
+ATTTTTAAATTTTTATGGAAAAATTTCGATTTTTTTTTTTGAAAAAAAAG
+CTTTTTTTAAATTTTTCTTTATTTTTGGAAAATCGAACATTTGCTATTTT
+TTTCGATTTATTAATTTTTTTGTTGGAATTTCTAAAAATCGATGTTTTTT
+TTTCAAAAATCAGCGGTTTTTCCGAAAAATGGCAAAAATTTTTTTAAAAA
+ACATTTATTTCTTTTCCTATTTTTCGAAAAATAAATAATTTTTTCTGGCA
+ATTTTTAATGAATTTTTGATCGGTAAACTCTTACAGTCCCGGAAATATCC
+TCTACAAAATCGACAACTTTCTTAATCCGAAACTCCACAGGCTCAATCAT
+CTCGAATAATGATTTTTCTGGAAAAAAACCAATTTGTTAAAAGTTTTATT
+TCCAAGCTATAATCTAACTAATAATCATATCCTTATCGGTGACCCCCACG
+ACAATAACATCAGAAGCGAGCTCGGCAGCCTTGTTGAGCAACACTTTGTG
+CCCATTGTGAAGCCGATCGAATGTGCCGCCCAACACGACTTTTTTGTACT
+TTTTCGCCGCCGCCAATTTTTCCGCGTTCTCCAGCAGCTTTTCCTCGCCG
+ATTAGCACATAATTCTCGGGATTTCCGCGGATTTCCGACACAACTAGACG
+GACGTCGAGCTTCGGGCATGAGCTCGCCGATGTTAGGTAGATTTTCGAGA
+CTAGCTCGTCGGTTCGCGGCTCGTCCGGGTTTAATCTGCAAGGAATCCTT
+GTTAACCTTGATTTTCGAGCCGGGAAAAAGCCCAAAGCACTTTACCTCAC
+ATAAAGCTTCGAGCTTAACGCGGCGGCCGCAGACGTGAGCAATTGCTTCA
+GTTTTTGCACATTTTTGCTATTTAACACGAGAAGTCCGTATTTCGAGCTC
+ATTGAGAATGATGAGAAATATCAGGGAATATTCCTCAAATTTTAAATAGA
+AAAATTCGCTGCCACGTTCGCTGCTCTTATCGGCTGCGCGTCTCTATTTC
+ACACACTGTCTCATCTCTCGTCTCGCGTCTCTCGTCTCTAACGCGTGACG
+GTGGAGCGCACTTCCCTCCTTTTTGCTGTAAAATCTTTCAGACATGCCGG
+AAACAAGAAAAACAAGAAATTATTGAACTGAAAATAATGTAAACGTACTC
+ATCGTATTTTTAGCTTCAAAATAAGATATCTTAGAGCATATAATATTGCT
+TCTAAACGAAAACCAAAACATCGCTGAAAATGTTGTGAATTTTATGAAAA
+TCTAGGATCATTTTTCCCATTTTTATGAAAAACAACAATAAAATGAGAAA
+AATTACATGGGAAAACCGAAGAAACTTAAATTTCGCGGTCAAAATTCGAA
+TAGAATTACTGTATTTTTCGCTCAGAGATATTTTGCGCGTCAAATATGCT
+GCGCGTGCGCATTTTCAGCGTTTTTTATTTAATAAAACAGTAATAAAATG
+ATTAAATGCATTTTGTGTGATTTTCAGCCCAAAATGTTTGAAATAAATTG
+TTGTTGTTCAAGCCAGCATTTTTAAAAACTTAAATATATGGGAAAACCAT
+AAAAATAACACAAAAGTTTGGCAAAATTTTGGAACTACAGTACTCTTTAA
+AGGCGCAAGCCCTTTAAGACAAATTTGTCGTGTCGAGACCGGACAAATAT
+TCTAAATTTCTTTTATACATACGCAGATTTAAAGTACAGAAGAGCGCATT
+TGCACATTGCGCAATTTCTAAATTTTTTCTAACAATAAAAATTAAAACCA
+AAATACTTTATTCAATACCACAAATACCACAAGTTCATTTATCTTATTCA
+ACCTCTTCCGCCGACGTCGTCTTGTTGTTGCTCTTCCCCTTCTTCTTAGA
+CTTCTGAAATTTTCTCATATATGCAAACGCGCTCCGATCTAACAAAAAAC
+CTTCTTCTTCTTTTTCTTCTTGTCTACATCTTCCTTCTTTGGCTGCTCTC
+CAGATTCTCCCCCGGCTCCCGGATCGCTCTTCCCAAAGTCCATCTCCGGC
+TTCAGCCCAACCTCAGGCGGCGCGATCATCAGTACCTGCTGGTATCCAGG
+ACCCTTGTAATCCGTCATACAATCCCAATCTGGTGGCTCCTGGGTATTTG
+ACTTAGACTTCTCAAACAGCTTCTGGATCCCATCAGCGATACGATCGTAC
+TCCACAAACTCAGCGACATCCTTGGGCTCACGGATGATGGTCAGAAGATC
+AAAGAACCCAGCAGTGGTCTCCGGAGTGGTTCTCCAAACCGACGCGACCA
+TCGGTGCAGTGATGCGACGTTTCAAGTGGAGCACGTCCTGTTCGCTTTCC
+TTGTTGAGCAGTGCCCATGGGAGAGCTCCGAGGAAGAACTCGAGCACCAT
+GTACCACCAGGACTCCATGTCGTCCTTGTAGCCGAGATTTTTCTGGGAAG
+AAAAAAGTTGTTTTAAAGAAATTGTGAACGGTAAGGTTACCCCCTGGTGA
+GCATGAACGCTCGCGTACTTGACGACTCCTCTGTAGTGAATCGCATTCTT
+TCTCATCTGCTCCTCAGCTTCGTCGTTCTTCTTGACGAATCTTAATTTTA
+AAAAAAGTTTTCGGGGTAGATTTACGACGCGTTGCGTGTCGCGTCGCGGT
+TCGATTTTAGTTGTAAAACTAAATGTATTTGTCCGTGTGGAGTACGCGAC
+TTTCCCACTCAAAATAGGATGGAATTGAATTCGGAGGTGTCACTGTTGCA
+AATTCGGATTGTCTGAATAAATATAAAGTGAGATTTTGAATTTTGCTCCA
+TTGATAATGGTGTTTTTTTTTGAAATTCTGCAAACATTAATTTCTAGAAA
+ATTTGAGTTTCCTCCAAAATTTTTCACAGAAAATTTGAATTCCCGCCAAA
+ATTTTTTCTCTGAAAATTTGAATTCCCGCCAAAATTTTTTCTCTGAAAAT
+TTGAATTCCCGCCAAAATTTTTTTCAGAAAATTTTGAACCCCGCTTAAAT
+TTTTCTGAACTAGGCTATTTTGTCTCGGCCATATCTGGGGTTGTGGTTTA
+CGGCGCGTTGCGTGTCGCGTCGCGGTTCGATTTTAGTTGTAAAACTAAAT
+GTATTTGTCCGTGTGGAGTACGCGACTTTCCCACGCGTTGTTCGTCAGGC
+AATTGTCAATGGAGCGCAAAAACTGCCGACCGCTCCAAATAACTACTTTT
+TGCACTTCATTGCATACACACAGCAGCTCGCGGCGTCGGCATGAGGCCCG
+CATTTCGCGCCTCACTGGAAGCCCCAGATGCCAAAAAATCTACCTCGGTC
+TCTTGCACAACCCGAAATCCAACAGGTAAACCTGATGGTGCTGTCCGTCA
+ATCTCTCTTCCAATACAGAAATGCGATGGCTTGATGTCGCGATGAATGAA
+TCCATTCCGGTGGAGGTCACGAATCGCGGCCAGCGTCTGCTCGGCCAAGT
+GAAGACCCGTCGCCATGCTGAACTTGCGATCCTTGTTCGTGTTCATCATC
+AGCTCGTATAGGTTCTCGCCATACTGAAATATGGAATTTGGCTGAAGTTA
+GGCAACGAAAAATGGTACCAATGGCATCACAATGAAGAGGAAGCGATTTG
+GAACCGTGCCACGTTCCTCGATATTCGTGAAGAATGGAGATGGGTGGTGG
+ATCGACGCGAGGACAACTGACATTTGACGAAGAAGCTGGAATTTTTTTTG
+CTCTCTAGAAACGGTTTTCACGGCGGCCGACAATTTCCGAGTTTGGAAAC
+TCACTGCACTTAGTCATGTAATTTTATAATGAGTGGCTAAACTCGGAAAT
+TGTCGGCCGCCGTTAAACCACAAGACAGTTGGTTCCTTCGCCGCGACCGA
+CACTTTCCGGGTTCCGCGCCGCACTATACAGAAGGCTGGCTGCGCGAGGC
+AGGCTAGACCGCGGCAGGTGTTTTGGCGCCTACATGGACTTGCTAGCTTG
+TCAACAAGGCAGCCTAAGCGTGCCTGCAAAAGGTAGGCAGGCACGCTTCT
+AAAACCGTGCCAACACACCATAAATAACTCACCGAGCTCTTCATGTTCAA
+CGCCTCGCATTTGACCGCAAAAAACTTCCCATCACTCTCGCGTTTTACCT
+TGTAAATCGAGCCGAACGTGCCCGTCGCCAGCGGTTTCGTGACTTCATAG
+GTGCCGTTTTGTGCTCGAATGAGCTCCTTTTGCGGTTGTCCAGGTCCGAC
+TGACGTCATTGATTTAACACCGAAATGTCACGATTATTCGGAAGTGAATC
+GATAATCGAAAATCGGAGACTCGAAACTTTTCGAAATAGATTTTATTATC
+TTTGTAGGGTTTTTGGAGTTTATGATGATAATGAGGAGGGGGGATTTTAT
+GTGGATTAAGAGGCTACGAGGAAAATATTTATTTTTTAAATATTTTATTG
+TCATTCTTTTCTTTTCTAGATTTTCACGTTTCTTATTATTAAAAAAAAGT
+TTTTCAGAATTTATTTCAAAATCCCGAACATAATCTGAAATTCAGAAATA
+CTACAAAAGAAAAACGAAAAAAAAACTGAGAAAAATGGTCCAGATTCTCC
+AGTATTGTTAGGCGTACCCCCCCCCCCCCCCTACCTACCTACCTTCCTTC
+CTCGCCTACATGCATACCTGCCTACCTACACGCCTGAGTGCCTGCCTACC
+TTCCTGCCTACGTTTATGTCTACATTTTTTGCCAGCCTTTTGCCAGTATA
+CTTTACGTGTGTTCTTAATTACGTGCCTATCTACTTACCTTTCTTCCTCG
+CCTACATGTATACCTGCCTACCTACACGCCTGCGTGCCCGCCTCCTGCCT
+ACCGACTCACCTACCTGTTTGCATACATGCCTGCCTACCTTCTTGACCAT
+GCCGAGGCGCCTATCTTACTACTTGCCTACCTACACGCCTGTCTATTGCC
+TACCTGTTTGGTTACATGTGCCTGTGCCGTACCTGTGCCTCAAAAACATC
+TTTATTTTGTAATAAATAATTTTAATAAAACTTTATAAAACAAAAAAAAT
+ACAAAATTGAAAATAACCTAACAAAAAGTCTTTTCAAACCCCTTCGAACT
+GCTCAACTGATAAAAATTCGTGTTATACTTCAACAATTTGAACTGCAAAT
+CCGATTTGACACAGCTAAACTTGTATTTTGTCGCTTTATTCCTGCACAAA
+TGTGCTCCTGGGCAATTGAGACTATTCGAATCGGTGTAGTAGGTGGTGAA
+GCTCTTTGAGCATCTTATTGTAGAGTGATCTTCTCGAAGACGGCCCAGAA
+TTGCGGTGATTGAGGGATTTGTGATGGTTCTGGGGATTTGATGTAATAAA
+TTTAAATTGTGTGGTTTAGATGCAGAAAAAAAAACTAAGAATTCAGACTA
+AGACTTGAAAAAGAGCCAAGAAAAGGGCGGAGCCTATTATCGATTTTTCC
+ACTTGCCGTTTATGAAGTTTATCTACACTTATATAGTCTATTATCAATAC
+TAAGTTAAACAGTATATGGTATAATAAATACTATGACTGCAAGAAAAATC
+AATAATAGGCTCCGCCTCTATATTTGTTTTTTCTCGTTTTAAATCCAAAC
+TTATTCTACGCCGAACCTATATTCTTTTATATTTTTTGAAATTATATATC
+CTTCTATTTATAAGATTTTTCCAGCCAAATTTTTTTTTCTCAGAAAAATT
+GAGTTTCCCGCCAAAATGGGTTTCTCAAAAAATTTGAATTTCCCGCCAAA
+ATTTTTTTTCTCAGAAATTTAAAATTTTCCGCAAAATTTTTCTCAGAAAA
+TTTGTATTCCCCGCCAAAAATGTTTTCTCATAAAACATGAATTTCCGTCA
+AAACTTTCTCATAAAATTTGAATTTCCCGCCAAAATTTTACGAGAAAATT
+TGAATTTCCAGCCAATCTTTTAATGAGAAAGTTTGAATTCCCACCAAAAT
+GTTTTTTTTTCTCAGAAAATTTGAATATTCCGCAAAAATGTTCTGAGGAA
+AATTGAATCTCTAGCCAATTTTTTCTCATAAAATTTGAATTTCCGGTCAG
+CTTTTTTCTGAAAAAGTTTGAATTTCGCGCAAATTTTTTTTCTCAGAAAT
+TTTAAACCTCTGGCTTTATTTTTCTCAAAAAAATTAAAATGTCCTGCCAT
+TTTTTTAAAAAAAAAATTCACAGAAAATTTGAATTTTTAATTTTAAAATT
+CACAGAAACTGACTTCCTTATCGACATGCCAATTGTCACACGATCCGCTG
+ATTTCAGAGCTTCACCGCCCGTAAAATTGCCACGTATCATTGAATCCACG
+TCAGCAGAGTCGGGAATTTCAAAAATTTTACTATCATCCATTTGTTTGCT
+GGAAGCGTTAATTATCGATTTTTATTTTTTTATTCGTTATATTAATTTTA
+TTCATATTTTTTGAAAAATAAAATCAATTTCACTCTCGGATTTCTGGCTT
+CCCTCATAAAATGAAATGAAAGAGTTTGCCGAACTAGGCCATTTTGGCTC
+GGACATATCTGGGGCAGATTTACGGCGCGTTGCGTCGCGGCTCGTTAAAA
+ATAGATTTATTTGTCCGTGTGGAGTACACGACCTTCTCACGCGTTGTCCG
+GCAGGCAATTGTCAATGGAGCGCGAAAAATTCAATGAGGAAGGCCAGAAT
+CCCGTGTTCACTGATTTTTTGAATTTACAATTTTTAAAGTATCGAATAAA
+AATTTTAATTGAAAAAATCGATTTTCAAAAAGTTTTAAAATTTTTTTAAA
+ATTTGAATTTAAAAATCGATTTTAAAAATTATTGATTTTCGAGCAAACCT
+TTTCAATTTGTACGGATGTTCCACGGGCTCATTGAGCCAAACACTATCGA
+TTAAAGATGGGCGTGTCACCACTTTTGCCACGCCCCTTTCATTCCGATAT
+TCCAATAACCCGACGAATATCTCTGATTCGTAATAGTTGGCGAACTCGGA
+AAAATAGGAATCGAACGATTTCGGCACGAGAAGATCAGACCACTCGAGAA
+ATGTGATGAAGCTCCCCGAGCTCTGAAAGTTTGGATAAATAGAGTTGTGA
+GCCTAGTGCAAGTTGAAAAAATCGATAAATTATCGATTTTCTGATTGTAC
+GAATTTAGGCGGGAATTCAAATTTTCTGAGAAAAATTTAGGCGAGAATTC
+AAATTTTCTGAGAAAAATTTAGGCGAGAATTCAAATTTTCAGAGAAAAAA
+TTTTGGCGGGAATTCAAATATTCTGAAAAAAAATTTGCCGGGAATTCAAA
+ATTTCTGAAAATAAATTTAGGCGAGAATTCAAATTTTCAGAGAAAAATTT
+TGGCGGGAATTCAAATTTTCTGAAAAAAATTTAGGCGAGAATTCAAATTT
+TCTGAGAAAAATTTAGGCGAGAATTCAAATTTTCAGAGAAAAAATTTTGG
+CGGGAATTCAAATTTTCTAAGAAAAATTTTGGCGGGAATTCACATTTTCT
+GAGTAAAACTTTGGCGGGAATTCAAATTTTCTGAGAAAAATTTAGGCGAG
+AATTCAAATTTTCAGAGAAAAAATTTTGGCGGGAATTCAAATATTCTGAA
+AAAAAATTTGCCGGGAATTCAAAATTTCTGAAAATAAATTTAGGCGAGAA
+TTCAAATTTTCAGAGAAAAATTTTGGCGGGAATTCAAATTTTCTAAGAAA
+AATTTTGGCGGGAATTCAAATTTTCTGAGTAAAACTCTCTGGCGGGAATT
+CAAATTTTCTGAGAAAAATTTAGGCGAGAATTCAAATTTTCAGAGAAAAA
+TTTTGGCGGGAATTCAAATTTTCAGAGAAAAAATTTTGGCGGGAATTCAA
+ATTTTCTGAAAAAAAATTTCGGCGGGAATTCAAATTTTCAGAAAAAAAAT
+TTTGGCGGGAATCCAAATTTTCTGAAAAAAAATTGGCCGGGAATTCAAAA
+TTTTTGAAAAACATTTTCGGCGAGACTTCAGGGGTTCTCATAAGAATTCA
+AATTTTCTGCAAAAAATTTTGGCGGGAATTCAAAATTTCTGAAAAAAAAT
+TTGCCGGGAATTCAAAATTTCTGAAAATAAATTTTGGCGGGAATTCAAAT
+TTTCTGCAAAAAATTTTGGCGGGAATTCAAATTTTCTGCAAAAAATTTTG
+GCGGGAATTCAAATTTTCTGAGAAAAATTTTGGCGGGAATTCAAATTTTC
+TGAGAAAAATTTTGGCGGGAATTCAAATTTTCTGAGAAAAATTTAGGCGA
+GAATTCAAATTTTCAGAGAAAAAATTTTGGCGGGAATTCAAATATTCTGA
+AAAAAAATTTAGGCGAGAATTCAAATTTTCTGAGAAAAATTTAGGCGAGA
+ATTCAAATTTTCAGAGAAAAATTTTTGGCGGGAATTCAAATATTCTGAAA
+AAAAATTTTGGCGAGAATTCAAATTTTCAGAGAAAAATTCTGGCGGGAAT
+TCAAATTTTCTAAGAAAAATTTTGGCGGGAATTCAAATTTTCTGAGTAAA
+ACTTTGGCGGGAATTCAAATTTTCTGAGAAAAATTTAGGCGAGAATTCAA
+ATTTTCAGAGAAAAAATTTTGGCGGGAATTCAAATATTCTGAAAAAAAAT
+TTGCCGGGAATTCAAAATTTCTGAAAATAAATTTAGGCGAGAATTCAAAT
+TTTCAGAGAAAAATTTTGGCGGGAATTCAAATTTTCTAAGAAAAATTTTG
+GCGGGAATTCACATTTTCTGAGAAAAATTTTGGCGGGAATTCAAATTTTC
+TGAGAAAAATTTAGGCGAGAATTCAAATTTTCTGAGAAAAATTTTGGCGG
+GAATTCAAAATTTCTGAAAATAAATTTTGGCGGGAATTCAAATTTTCTGC
+AAAAAATTTTGGCGGGAATTCAAAATTTCTGAAAAAAAATTTGCCGGGAA
+TTCAAAATTTCTGAAAATAAATTTTGGCGGGAATTCAAATTTTCTGCAAA
+AAATTTTGGCGGGAATTCAAATTTTCTGCAAAAAATTTTGGCGGGAATTC
+AAATTTTCTGAGAAAAATTTTGGCGGGAATTCAAATTTTCTGAGAAAAAT
+TTTGGCGGGAATTCTAATTTTCTGAGAACATTTTTGGCGGAAATTCAAAT
+TTTCTGAGAACATTTTTGGCGGGAATTCAAATTTTCTGAGAAAAATTGTG
+GCGGGAATTCAAATTTTCTGAGAAAAATTTAGGCGAGAATTCAAATTTTC
+AGAGAAAAAATTTTGGCGGGAATTCAAATTTTCTAGAAATCAATTTTTTC
+AGAATTTCAGAAAACACCACCCCGGCTATCAATGGAGCGCATTTTCAAAG
+TCTCACTTTATATTTATTCAGGCAATCCGAATTTGCAACAGTGACACCTC
+CGAATTCAATTCCATCCAATTTTGATTTCCCATAAAAATCTGGAAACGAG
+TCAACTGATATTCCTTTGAGACGCTTCAACTCTTCTAGAAATTCGAAAAA
+CGGGCGACTTGTAGTTGCCACGTATGTTTGGAGATGGCCGCCGAAACTGG
+AAAAAAAATTTAAAATAAACTGACAAGTCTATATATTTTTTCTTTAAATT
+TTTTTAATCGAAAAGCACCCCTATTATATAAATTCTTTTTTAACCTACCA
+TTTTTAATAATTGATGGCCGAGTTTTCTTTTTTAGGCCATGTTCAAAAAG
+CCGGTCGGTACCGGTTTTTGGTGACCGAATTTTCAAATTTTCTAGGCCAC
+GTAGAAAAACCAGGTCTTCTTTTCACACATTGATTGTTTAATTTTCTCAA
+AGAACCCCCTCTCCTATAAAATCACGGTTAATAATGGGCGATAAGTCGAT
+GGCCGAGTTTTTTTTATATATTTCTAGGCCATGTAGCAAAAACTGACCCT
+TTTTAACCCCAGAATGTTCTCAAAAATCGTATTTTTTAATTGTGGAAAAG
+CCCAGAAAATTATGTATGCTGCAAAATCACAAGTCGGCGGCCGAGTTTTC
+TCTCTTCCTAGGCCACGCTGCAAAAACTAACCTTCCGTTTACATATTGAC
+TTTTTCAAATAATTTCAAATAAAAATTATTCACTTATAAAATCATTTACT
+TCATGATTGAAAGCTTTTGCAATTGGTTAAAACCGGAAATAAGTCGATGG
+CCGAGTTTTCTCTTTTCTAGGCCACGTACCAAAAGTGTCCCTTTTTTACC
+CCAGAATGTTGTCAAAAATCGTACTTTTTATTTGTGGAAAAGCTCGGAAA
+ATTATGTTGTAAAAAATGAGTCAAGTCGGTGGCCGAGTTTTCTCGTTTTC
+TAGGCCACGCTGCTTAAACTGACCTTCCATTTACATTTTGGCTTTTAAAT
+TCAAATAAAAATTATTCCCTCATAAAATCGTTTACTGTCATTGTGAGAGC
+GGTTAAAAACAGGAAAAAAAATGGTGGCCGAGTTTTTTTTTCTAGGCCAC
+ATAGCAAAAAACTCACCTAGTATACACATGAGCAGCTAACAACACATTCT
+GCCATCTAACATTATTATAAATAGGCGGAGTACATACAACCAAATCCTTC
+GGCTTATTATCCGCCGGCAAATATCGAATTTTCGCGGTATGCCCATTCAC
+AAGAAGCTCCAGCTCCGTGAGCTCTTCCTCAAGCACTATAGTACCCACAA
+GTGTCACGTATTTGCATAAATTATGCGGAGTTGCTCTGTGAATTTGAAGT
+GGTTCGAGTACGGTTTTTGTGTCGTCACTTCGGATTGCGATAATCTTACG
+ACGTTCCCAATGTGCATCCCGAGGCGCGATAAAGGTTAGTGTTACTTGGT
+TTTTGTAGAGACTGAAAAATTTCAAAAAACTTAAAAACTAACGTAGTTTA
+AAACATTATTCTTCTTTTTTTATTCTGAGATATTTTGATTTTGAAAAAAA
+AAAATTTTTTTTACGAAAAAAAAATTGGCAAAATACCTCAAAAACTGTGA
+GTTTGTTGAAATTTAGTTTTTACAACCACGGGAATTAATTTTTTAAATTA
+AAAATATTTTACGTGTAGTCCTCTCGAATAATTTTGAAAAATATATGAAG
+TGTTGAATTCTGCCGAGTTTTTTTGTCCGAGTGGACTACAAAAGTGCAAA
+GAATTTGGAATTTTTCAAACTTTATATTTAACAGCAATCATCAACAACTT
+AAAAAAATTTAGATTAAAAAATTTTTTTTGGAAGTTTTCGAAAAAAATTT
+TGGAAAAATTTTTAATTTTCAGAAAAAAAAACCAGTTTGATTTTTTTCTT
+AAATTCTTTTTTGAAAATTTGTTGAAACTTTTTTTTAAATGCTAGACTTT
+TTTTTTGAATTTTCACGCGGTTCTGGTTTCCCTCATATTTTGAGATAGAA
+GAGTTTGCCGAACTAGGCCATTTTGGCTCGGCCATATCTGGGGTAGATTT
+ACGGCGCGTTGCTTGTCGCGTCGCGGCTCGATTTTAGTTGTAAAACTAAA
+TGTATTTGTCCGTGTGGAGTACACGACTTTCCCACGCGTTAGGCGATTAT
+CAATGGAGCGCGAAAAATGCAATGAGGAAGGCCAGAACCCCGTGAAAAAT
+ACATTTTAAAAAATACTTGAAAAATGTTTAAATTTTCTTTTTAATTTTAA
+ATTTGAAATTTTGTAACTTTACAAAAAAATAATTTTTCGAAATTTTTTTC
+AAATATTTTTTTTCGAATTCTTTTTGTTGAAATTTCAATTCTCTGTTCTA
+AAAATCAATATTCCTTACCTGTATCCCACTCCATAATAGTACGCAGAAAC
+AAAAAATAGGTCTTTCTCGTCGTTATCCAATTCTTTAATCTTATTAGTGT
+ATGAATTTCGAACACGTCTTAATGCAGGCAAGGGATGTATTGAAATATGT
+ACAAATGCTAATAATATTACAAATAGATATAGGGTCCTGCAACGAATTAT
+CAACTGCTCGTAGAGTACGGAATAGGGTTTGAATTGAAAATTGTTCAGTT
+TCGTGTCGGAATTCATTTTTATTATGGGGAGGAAAACAATCTAGTGTGGT
+GGTAGTGGTAATGACAATCGCTATTTGAAATCATGTTGAATAGCTGCGAT
+AAGTATCGGGCGCCAGCGTGGCCTAGGATTTGGGAAAACTCTTCCACCAG
+AAGCTAGTCGTGGCCCAGGCTTTGAAATTTGATTATTTGATCAAGAAATT
+TACAACTAAATTTAAAATCAACAGTTAAGACATTTTTCATAGACTTTTCG
+AAAAATTTCTGATTTTTCCATATCAAATAACCTCGGTACGCATCTAACCG
+TCAGTTGCCTCGTGGCCTAGAACTTTTGAAAACTCTTCCACGAGAAGATC
+ACCGTAGCCTAGAAAGTTTTGAAACTTGTGTAGTTCGCTTGGAATTTTTT
+TTTGGTTTTTTTGTCAACTAACTAGGTTCAATAGCTATTAAAAAGTTGCA
+AAATTGGGCAATTTTTGTAAAAATTCACAATTTTGAAACTTCTCTAAAAT
+TATTAATTTTGTAGTAAGAGGACTCAAAATTGATCTTCAAACACTAAAAA
+ATAGCCCCTTTTTAGAATATAGTGGTTTCGAATATTTTTTGAAAAATTAT
+TTTTTTTTACCCAAAAAAAAGGACAGTCATGGCTGAAAAAAAATTTGGAA
+AAAATAAAAAAATTGTCTAAATTTGTTGAAAACGGGTAATTCATGCATTC
+TGAATTCAGAAAATCTAGGTTTAACCCATCAAAAACCATTAAAAGCGGCA
+AAAATGGGTATTTCATTGTAAAAATAATGCATATACAATAAACAATGTAG
+AGGAATGTTCAAAATCTGTAGTTTTTTTGAAATTTTTTTTTTATTTTTTG
+GTTATTTTTTTTGCAAATTTTCTCGTATATTTAATTAGTTAGTTTGCATG
+TTACATGCTAATGAAAAGGTTTTTTTTGCATCCTGATACATATAAAAACC
+GAGAAATTCACAATTTCACAATCAGTAAGGTATTTAATTTTTGTTAACTT
+TAGTCTTCTGCTCCTCTAAAGCTTCTGGAAGAGGACACTTTCTAAATTTT
+CAAAATATTTTTTGCGCCACTTTCCTGTCAAATTTCTGGCATTATTACAT
+CCAAAACCCAATAAAAATCGGAATTCCATAGCTACGACAACGTCAGCAAA
+AGCGGAAAGAAATTTTGTTTGCCTGTCTAACGAGTCACAAAGCATACACT
+GACGTTTCTATCAGAAAAGACAGGATTTCGTATCAAAACAAAAATTGGGT
+GCGATTGCTCGATGCACCATGTGATATTTTGCTTTTTTTAAAAATTATTT
+TGCTCGTAATGTATGGTGCACTTATTCCGTGGCTGCAGAATTTGCACGCG
+GTGTCATAATGCCCATTTCGACTTGATCTACGTAGATCTACAAAAAAATG
+CGGGAGTTGAGACGCAGAGGTAGGGCTCAACTGATTTCGTTTGGTTAAGA
+GCGTGCTGACGTCACATTTTTATGGGCAAAAAATTCCCGCATTTTTTATA
+GATCAAACCGTAATGGGACAGCCTGACACCATGTGAATGCAAACTTTACG
+CGAAAATTTTTAGATTTTTAATAATCTTAGAATTAGCTATGGTTTTATAG
+AATAATATCAAAATTATCCAAAAAAAAAAACACATTTTTTCAAAATTTTA
+GATTTCCAGTTTCTATTTGAACTTTAAAAGACTAATCCAAATTTTGTTTT
+GTTTCAACGATTTTTCATTGATCTCTCCAAAGAATTCATTGAAACACATC
+ATTCACAAAACTAAAAACTCCCCGACTTGGCTTTCATTCCGAGATGACAA
+ACTTTTTGGTGGCAAAGGTTCTTTGGGGGCATAGTATCCAAGGAGACAAA
+GTATCCAGTAGACAAACTGGGGTGTATCTTGGGGGGCATATCTTTGGTGA
+CAACCTTTTTTTCGACTAGATTTTTATATGTATTTTTCAACTAATTTTTG
+TTCACATTTTTCTGGAATAAGTTTTTTAATGCAATTTTCAATCGATTATC
+GGTTATAATTCCCTCACAATTGAATGTATGAACGATGGTCTTTTGGGAAA
+AGCTGTAAAACGTCCAACTAACTTGGAATATCGTGAGGCTCTTCCTGATG
+GTCTGATCCTTCAGCTCCGAAGGATCACATGGGTACCTTCTGATGTTCTG
+ATCCTTCAGATAAGAAGGATCGTAAGGGTACCTCCTGATGGTCTGATCCT
+TCAGATCCAAAGGATCACGAGGCTCTTCCTGATGTTCTGATCCTTCAGCT
+CCGAAGGATCACATGGGCACCTTCTGATGATCTGATCCTTCAGATAAGAA
+GGATCGTAAGGGTACCACTTGATGGTCTGATCCTTCAGCTCCAAAGGATC
+ACGAGGCTCTTCCTGATGTTCTGATCCTTCAGCTTCGACAGATCATATGG
+ATTTTTGACAAAATTTGAAAAAAAAAATTTTGAAAAAAAACTCGAAATTT
+TTTTTTGTTATTCTTCATTCTTTAAAGAATAGTTCAAATTTATCATGATA
+GGACCGAAAACTTTCAAGAAACAGTATAACTATACATGATAATCAGCTTC
+TACCAAATAATGATAAATTCTCCGCGATGACAAACTTTTCGGTGACAAAG
+TATCTTGGTGGACAAACAAAAATTACCGAAAACTGATGTAAGGAATAGTG
+AAATAGAGTCCTATGGACTATTAAACATGTTCAGTAGGTGTATTCAGGAC
+TGTCCGTCAAAATAAAAAAAAGTTTGTCAGACGAAGTTCGAACCTGGGAC
+CTGTAGGATGCAAAGTGCGCTCACTACCACTACACCAGCTATGCGAAAGT
+CGGCGAGCCTCATCGAAGGCTATTATAAAACTTAGTTCGCACGAGTATGA
+TCGACATTCAACAAACAGTAATATCTCTCAACAAGAATTTCTTCATGGAA
+TTGAGGTCATTTGACTATTTTTATCGGTTTTTCAAGTTGAGCATAGGGTC
+TTTTAATTTTTTGAGCATAGAAAATCATGAAAGCTGCCTGTTCCTTGTAT
+CCTGGATCGAAATAGACGTATCTGGCCTAAAATATTTCCTGAACAGTGAT
+CATTTCATGTCCATTGTGTGTTTCTCTGTATTTTGAACCAGAAAGTTGAA
+CAAAAATGATAATATTATATCGAAAAATGGAACAAATACAAATAATTTTT
+AGGCCTAATCAAATTTCCTCCGGATATTGTTTTTTTTGTCATGATTATAT
+GTGTCTAAATTTTTTATAATGTGTTTTATAACAAAATTCGTCATTATTTC
+CTTCATTTCAAGCAAAATTTAACAGTTCGAGCTTAAAAATAGATGTTGCA
+AAAAATTTAATTCGTTTCGATGAATACGGTATACGGTCGGTGTTTGCGTA
+CTTTGGCGTTTGCGTATGAAGCATCCTATTTGACGCACGAAACTTTCAAT
+GAAATTTAATGCAAATTCTGCATCGAAAAGGACATTACGATGGAAATAAT
+GACGAATTTAATTATAAAACACATTATAAAAAATTTAAAAACATATAATC
+ATGACAAAAAAAACAATGTCCGGAAAAAATTTGATTAGGCCTAAAATTTA
+TTTTTTATTTTTTTCCATTTATCGATTCAATATCAACATTTTTGTTCGAC
+TTTCTAGCTCAAAATTCATAGAAACTCACGATGGACATGAAATGATCACT
+TTTCAGGAAATATTTTAGGCCAGATACGTCTATTTCGATCCAGGATACAA
+GGAACAGGCAGCTTTCATGATTTTCTATGATCAAAAAATTAAAAGACCCT
+ATGCTCAACTTGAAAAACCGATAAAAATAGTCAAATGACCTCAATTCCAT
+GAAGAAATTCTTGTTGAGAGATATTACTGTTTGTTGAATGTCGATCATAC
+TCGTGCGAACTAAGTTTTATAATAGCCTTCGATGAGGCTCGCCGACTTTC
+GCATAGCTGGTGTAGTGGTAGTGAGCACACTTTGCATCCTACAGGTCCCA
+GGTTCGAACTTCGTCTGACAAACTTTTTTTTATTTTGACGGACAGTCCTG
+AATACACCTACTGAACATGTTTAATAGTCCATAGGACTCTATTTCACTAT
+TCCTTACATCAGTTTTCGGTAATTTTTGTTTGTCCACCAAGATACTTTGT
+CACCGAAAAGTTTGTCATCGCGGAGAATTTATCATTATTTGGTAGAAGCT
+GATTATCATGTATAGTTATACTGTTTCTTGAAAGTTTTCGGTCCTATCAT
+GATAAATTTGAACTATTCTTTAAAGAATGAAGAATAACAAAAAAAAATTT
+CGAGTTTTTTTTCAAAATTTTTTTTTTCAAATTTTGTCAAAAATCCATAT
+GATCCGTCGAAGCTGAAGGATCAGAACATCAGGAGGTACCCATGTGATCA
+TTCGGCTCTGAAAGATCAGATCATCAGGCAGAGCCTCATGTTCTTTTGGA
+GCTGAAGGATCAGAACATCAGGAAGAGCCTCATGATCCTTTGGATCTGAA
+GGATCAGACCATCAGGAGGTACCCTTACGATCCTTCTTATCTGAAAGATC
+AGATCATCAGAAGGTACCATGTGATCCTTCGGATCGGAAGGATCAGATCA
+TCAGGCAGAGCCTCATGTTCTTTTGGAGCTGAAGGATCAGAACATCAGGA
+AGAGCCTCGTGATCCTTTGGAGCTAAAGGATCAGACCATCAGGAGGTACC
+CTTACGATCCTTCTTATCTGAAGGATCAGAACATCAGAAGGTACCCATGT
+GATCCTTCGGAGCTGAAGGATCAGACCATCAGGAAGAGCCTCACGATATT
+CCAAGTTAGTTGGACGTTTTACAGCTTTTCCCAAAAGACCATCGTTCATA
+CATTCAATTGTGAGGGAATTATAACCGAAAATCGATTGAAAATTGCATTA
+AAAAACTTATTCCAGAAAAATGTGAACAAAAATTAGTTGAAAAATACATA
+TAAAAATCTAGTTGAAAAAAAGGTTGTCACCAAAGATATGCCCCCCAAGA
+TACACCCCAGTTTGTCTACTGGATACTTTGTCTCCTTGGATACTATGCCC
+CCAAAGAACCTTTGCCACCAAAAAGTTTGTCATCTCGGAAAGAAGGCCCC
+CCGACTTTGCGCGTAAGATATGGTGAGACCCTAATACATCATATTTGACG
+CGCAAAATATCTCGTAGCGAAAACTACAGTAATTTTTTAACCGTCTACTG
+TAGCGCTTTTGTAGATTTACGGGATCTCGATTTTTTTAATGATTAAAATT
+AAACAAAAAATGAGAAAAGAACACGAAGAAACGAAGAAAAATGAAATATC
+GATGTCACTTTTCGGAAAAAAAATTAATTTCAAAAATTGAGCCCGTAAAT
+TTACACATGCGCTACGGTAGGCATTTAAAGAATTACTGTAGTTTTCGCTA
+CGAGAAATTTTGCGCGTCAAATATATCGCACAATACGCATTCTCAGAATT
+TTGTGTTCCCGGAATAATTTATTTATTGGTTTTTTTGGTTGTATTGGTCC
+CAAAAATCAACAAAAAAAAATTTTTATGAAAAATTTCTGTTTTCTTCCGT
+TTAAAATCAAAAGTTGGTTTTTTTTGTTGCTTTTTTTGATAAATTTTTGC
+AACCACCCTGATTTATATTCCCATAAATATTTAATGTCCCGCTTATGATA
+TCTACTGCTTCTTTGCAAAATTCCTACCTGCGGACCAAATACACCATACT
+TGACGCGCACTTTTTTTTTGATTTTCAGCTGGACAAACACATTTTCAGCA
+TGATTCTGACTTATTTATTTAACTCTTATCACTCTTATCGTTAAAAAACG
+CCCTTATAATCATCAACCTATTTTCATTGTCATTCAAAAAAAAAAACTAT
+TTCGTACTCGTCGATCGTACTAATTTGTCATCGTTCCGTTCCGTCGAGCA
+AAAATCAATGTAGTTTTACGTTTTCCGTTGAAAAAAAATCCAAAAAAAAA
+TCCAAAAAAAATCCAAAAAAAAATTCCTTGTTAATTAAAACCGTGAATAA
+AAAATTCAAATAAAAAGTTCAAACGTTTCGTTATAAAAATGTACACCGGT
+AAGCTCAAAAATATACATTTCAGATTCTAACAATGTGCGACGATACGCTC
+GCATTTTGTAGTCCAGCTCCATTCAGTGATGATGTAGAGGTTATTAAACA
+ACGTGAGGCGATCGATTATTCCACACAAATCACTCTGGAAGATGCGATTT
+CTGGGAACGGTAAGTGCGCTCCGTTGTACTCATAGTTCGCTGAATGAAGG
+CATGTATAAGTTCTCAAATTTTCAAATGAAAATTGCCAAAAAAGGTTTTT
+AGTTAAAATTTAAAAAATTATCGATTTTTAAATTTATGAAAATTTTTTCG
+AAAAATTTGTGTTTTTTGTTTTTGTTTTATTGATTTATTGATTTTTTGGC
+GAAAATGTGAAAAATCGAAAAATTATGGATTTTTTCTTGGAATTAAAAAA
+AAAAAACTTTATCGGCTAAGCGAAACTTGCTTTTTCGGTTTATTGATTTA
+TTGATTTACTTGAAAAAGTACTTGAAAAAATCAATACTTTTATCACGGGG
+ATCTGGTCTTCCACATTAAACTTTTCGCGCTCCATTGAGAATCGCCCGCC
+GGACAACGCATGGGAAAGCCGTGTACTCCACACGGACAAATACAATTAGT
+TTTACAACTAAAATCGAGCCGCGACGCGACACGCAACGCGCCGTAAATCT
+ACCCCAGATATGGTCTGGTCTAGTTCGGCAAAAACTCTTCCATTTCAATT
+TATGAGGGAAGCCAGAAATCTTTGTTTTTATTTTATTTTGAAATCTCTAA
+ATTATCGATTTTTTGGAAAAAAAGTTGTTTGAAAATTCGATAATTTTTTA
+ATGATTTTTTGGAAAAATTAAAATTTTCGCTTTTCAAAAAAATCAAAAAT
+TATTGATTTTTGAAAAAAAAAACACGGCATGCAATTCCTAGACCACCAAT
+CAAAAACCTCTTCCAGTGACTCGTCCGGTCCGTGTCTACGCTGACGGTGT
+CTACGATATGTTCCACTACGGCCACGCGAATCAATTCCTGCAGATCAAAC
+AAACTCTTCCGAATGTCTACCTTATTGTTGGCGGTGAGTTCGGCCCGCGA
+AATTCAAAATTTTTAATTTAAAAAAAAAACGATTTTTTCCAGTATGTTCC
+GACGAAGAGACTATGAAGAATAAGGGGAGAACTGTGCAGGGCGAAGAAGA
+GCGGTACGAGGCGATTCGGCATTGCCGGTACGTCGACGAGGTGTATAAGG
+CGTCGCCGTGGACATGTCCGATACCGTTTTTGAAGGAGTTGAAGGTAAAT
+TGCGCGTGAGATTCGGTGTTTGCACAGTTTTATCTCCAAAAACGAAGGAA
+ATTTTATACCTAAATTTCGGAAAAAAATCAATAAATTATTGCCTTTTTTA
+AACGTCACAAAATCGATAATAATTTGAAAATCACAATTTTTTTTTTATTT
+TCAAAATTTCGTTGTTCTATCACGGGAACGCAAATTTCTGAGAATGCGTA
+CTACACAACACATTTGACGCGCAAAATATCTCGTAGCGAAAACTACAGTA
+ATTTGTTAAATGACTACTGTAGCGCGCTAGTGTCGATTTACGGGCTCTAT
+TTTAAGCTCAATTTTAATTTCTATCGATAAATATATGATACAAAATATTG
+ATCCCGTAAACCGACACTAGCGCGCTACAGTAGTCATTTAATGAGTCACT
+GTAGTTTTCGCTACAAGATATTTTGCGCGTCAGATATGTTGCGCAATACG
+CATTCTCAGAATTTTGTGTACCCCGTAATAAAAATTCGAGTTTTTCTAAA
+CAAAAAGTTTAATTTAAAAAACCTCTAATATTCGAGATATTCGATTGGCG
+ATTTATTGATCTATTGATTTTTCGATAAATATTGATTTTTCAATTTTTAC
+AATATTCGAAACAATTATCGAAATTTCAAAAAACTAACAAAAAATATTTG
+CGGAGGAAAATCGATAACTTTTCAATGTATATTTTCTGAAATTCCATAAA
+ATTGATTTTTCTAAATTTAATTTGTTCGATTTTCGGGTTCTCGGTTTTCC
+TAATTTCTGTAATTTTGAGTCGATAATTTTTTGTTTTTTTTTTTCAATTG
+AAACTTTTATTGATCAAGGATTTCTGGCTTCCCTCATAAATTGAAATAAG
+AAGAGTTTGCCGAACTAGGCCATTCTGGCTCGGCCATATCTGGGGTAGAA
+TTACGGCGCGTTTCGTGTCGCGTCGCGCCTCGATTTTAGTTGTAAAACTA
+AATGTATTTGTCCGTGTGGAGTACACGACTTTCCCACGCGTTGTCCGGCA
+GGTGATTGTCAATGGAGCGCGAAAAATGCAATGAGGAAAGCCAGAACCCC
+GTGATTGATTATTGAGTTTTGGAAAACTATTTTAAAAAACCTGATTTGAA
+AGAAAATATCGGTAATTTTTCGGATTTTTAACAAGAAAAAGGTTTTTATT
+TCCGGAAACTTTCATTTAATAATTATTTATTTATTGATTTCTCGGAAAAA
+TTTGCCGAAATCTATCGAACTATAGTCGAACAATTGGACGAAAAGTCGAA
+AAAAAAATTCTAGGCCACGAATTTCCTCTTCCAGGTTGACTTTATGTCAC
+ACGACGCTCTGCCATACCAAGGTCCCGCCGGAGAAGACATCTACGAGAAG
+CACCGCACTGCTGGCATGTTCCTGGAGACGCAGAGAACCGAAGGAATATC
+GACGAGCGATTCGATTTGTCGAATTATCCGCGACTACGACACGTATGTCA
+GAAGAAATTTGCAGAGAGGATATTCGGCCACCGATTTGAACGTTGGCTTT
+TTTACAGTGAGCCTGGCCTAGAAAGGGGTGGCCTAGAAAGAGGTGGCCTA
+GAAAAACAAAACTCTTCCATTTTTTTCAGACCAGCAAATATCGTCTGCAA
+GACACCGTAGTGGGAATAAAAGAAATGGGCCGTGGCCTGCTGCAAACGTG
+GAAAACGAATGCGGATTACTTGATTGAAGGATTCTTGACGACATTTGCCA
+TCAGTGATCCGAAACCGTTGCCGAACAACAAAAGTGCCGATGAAAATGTG
+GAAAATAGGGAGAATATTGAGAATTTTTAGAAAAAATTCGTGTAAATTAT
+GGGAATAAAAATTTGAATACTCGTGAATGTTTACTGAATTTATGCAATTT
+ATTTTTTGAAATTTTCAATTTTTTTGGAAAATTTTTTTTTCTTAGGCTTA
+GGCTTAGTCTTTGGCTTTGTTTTAGGATTAGGCTCAGGCTTAGGCTTAGG
+CTTAGACAAAAACTTAAGCTTAGGCTTAGGCTTTTGATTAGGCTTAGGAT
+TAGTCTGTCTTTCACTTAGGTTTGGCGTCATTGGCGAGCGTTAGCTCGCT
+ATTTAGGCTTGGGTTAATTAGGCTTAGGCTTAGGCCTAGCTTTAAACTTA
+GGCTTAGGCTTAGGCTTAGAATCAGGCGGGCTAGGGAAAAAAAGAGAAAT
+TCCAAAAATTCCAGAAAAAAGGAAAAAAGGTACATCCCGAAGTCGGGTCA
+AAAAATAAAGTGAAGAAATGAAATTTTCACGAAAATGAATGAATATTTTT
+GAGTCTCGCGGATTTATTTTCATAATCATATTCTGAACGTATTATTGACT
+CGTCGTGTGGGACATTTCAATGGATTTTCCGTAAAAATCTCTGTAGAATT
+CCGCATCGGTCAACGATTCTTCACAAGAGCCAAACTCGGCGAGTCGGTCA
+AACAAATGTTTGAGCTCCTGAAGAGTAGTTCAAAATTATATATGAATTGA
+TTTATCTTGCAAACCTTTCTCCGTTTGTCGGTAAAAAGTCCTTCGGGGCA
+GATTTCCGTATCAATCAGACGATTTGCAATGTATACAATCCACATGAGAT
+TTGTTCGCCTTGAGAATTTCTCCCAGTTGCCCCTGGAACGTTAATTTTTC
+TGAATTTCTAGAAAGGATATAGAAATAGCAACAAAAAAAAAAATTTATCC
+AAATAATGAGCTATTTAATGTAGTTTATATTACTACAAATACTTTTCTCA
+TAAGAACGTCTTGTTCTTGATAAATGTGTGCTTTAAGAAAAAAAAAAGTC
+AAAAATAGAGTCCTGAGATGTCGGGCGTTGTACCTATTAGGGGTGTCAAT
+AAGTTCCGGGTCAAAATTCATAACTTTTTTCGTAGCAAATCGATTTTCTT
+GAAAATGTGGGAATTTATGTTATCAAACATGGTCTTTCATTTGACGGCAC
+TTTCAAAAAGTTTTGACCACTCCATGTACCCTAGCTCGGATCCACTTTTT
+TCAGGCGTATGCCCGATCTCGCTTCTTTGTAACTTTCAATTGAGACTTAT
+GTGCGGATTTTGATTTATTAAGTATACAATGTAAGAATACAATAAAAATT
+TGAGAAAAAATTCGTTCAAAAAAACAATTTTTTTGATCGGCAAAAAACCC
+TCGAAAAAAATTTTGTCGAAAACTCTTGATTTTTTGTACAGGAATGATGC
+AACCAATTCTGAACAATTTTTTAACACATAAAAGTTTTGAATTTAAGGCG
+TCACACACAAGCGGCAATGGAAAAAATGATTTTTTAGTGAATTTTTTGAA
+ATTTTTGAGAAATTCTCGAAATCTAAATATTAAATTCAAATGTTTTGTGT
+GTTGAAAAATTGTTCAGAATTGGTTGCATCACTCCTGTACAAAAAATCCA
+GAATTTCCGACAAAAATTTTTCCGAGGATTTTTTTGACGAACCAAAAAAA
+TTTGTTTTTTTGAAGGAATTTTTTCTCAAATTTTTATTGTATTCTTACAT
+TGTATACTTAATAATTCAAAATCCGCACATAAGTATCAATTTAAAGTTTC
+AAAGAAGCAAGATCGGGCATACGCCTGAAAAAAGTAGATCCGAGCTAGGG
+TACATGGAGTGGTCAAAACTTTTTGAAAGTGCCGTCAAATGAAAGACCAT
+GTTTGATAACATAAATTCCCACACTTTTAGAAAAATCGATCAGCCACGAA
+AAAAGTTATGAATTTTGACCGGTAACTTATTGTGCTACATGCTTGTTGCG
+AAATATACCTATTTACCTATACCTATACCTATACCTGCAATTTTCTCTCA
+TCTCTCGATATACTTCAAATTGTGGAGCATCTGGTCCTTCAAAAATCGTC
+GTATCCTCTTCCAAATCCCAGTAGATAGTTGTCGAATCTAAAATTATATA
+TTTTTAATTATAAATTGTATATTTTTTTAATTTAAAAAATAACAAACCTT
+TCGAAATGCGGCTAAGTGTGAAATCAATAATATTGACCTTAATTCCATGG
+GTCCTCAGTGGAATTTTCTGCCCATGCACAGTGTAGGAGAGCTCTTCCAC
+TCCGTTCCGATCGATCAGCACATTACTAAGATTTAAGTCCCTGTGCTCGA
+ATTCAAGAGCTGCTTCAGCTGCAACCATTGAGAGAACGAGCTGGTGAATG
+ATGGAAAATAGTTCATCTTCACTTTCAAGGACAAAATCTGCCAGCGAGAT
+TCCACCATTTGCCGAGACGAAAAGGATAAAGTTTTGATGTTCTGAAGAAT
+AAACATCTGGCCTCAAATGTTCGGATTCATTGAGCTTATCGTAGGCATCC
+CAAGCTCTCAGTAATCCCTTAGGATATTCCCCCATGACTATTTGGGCTGA
+AATCATTTCGATAAAATTCGGCGTAGAATTCCAAGAATTTGGGTCTCTCA
+ACGCCGACAGTTCCTTCATCACAATCACCTCTGACAAAACGGCGTGGGTT
+GTTGGAATTTCCACGGATTGATTTCCATAGAAACATCCGTTGTTTTCGAA
+TGGCAAAACTTTGATAGCAACCGGTCTACCATTCCAGACAGTTGAGAAGA
+CTTCACCGTACGCTCCTTCGCCGAGCTTCTTCACTTTTCGAGCATCTAGC
+GCCGACGTTGGTAGGCTACCCCATGGTTTTGCTTCTTTTTGGCCAACAAC
+ACGGAGAAGTTGTGCCATGGACGGATCTTTATTGTGAAATGTGATACTGC
+CAATGGGGATATTTCTAGAATCAGGATGAGCTGACCGAGCACTTGGAGCT
+CTTTTGTTCAGTTCAGCAAGCATGCACAGTTCGAAAGCATGCACAGTGCG
+AAAATGACTTTTCTGAAATTGTCATCAAAAGTTCATTTTGAAAATTCGTT
+TCGGCAAAAAATGCAAATGCATTTCTGAAACTCACCAGTTGTCTCTGAAA
+TCGTCGTTCGTTGGTCATGTCGAGTGCAAGAACGGTGGTGGTGACCACTG
+CCGTCTTCGTGAACCGCATCCAAGACATGTTTCGGGAGATAACTATAGAA
+ATGAAGTTTTGAAAAAAAAACTCAAGACCACAATTATTGAAACACGTTAT
+TAGGCCAATAACTTCACACGTGAATTAATACATTATTCATGTATTTTTCT
+TTGACTGTTATCACGGGTTTCTGGCTCACGGTAGTTCAGCCACGGTAGCA
+CAGAAAATAGATGACCACGTTCATGATAATCAGTCTGAAACCTATATTGG
+CTGCTATCTCGAAAACTCTCTAAAAACGCGTTTTGAGAAATTATTGATTT
+TTTGGAGAAAATCAGAAATTATTGATTTTTTGGAGAAAATGGGAAATTTT
+TCATTTTTATTGGGGAAAATCAGAAATTATTGATTTTTGGAGAAAATCAA
+AAATTATTGGTAATTTGAAGCAGGGGTGGGCAGCAATTGCCGTTCGGCAA
+ATACGCAAATTACCGGTGTGCCGATTTTCCGGGAATTTTCATTTTCGGCA
+GTTTGCCGGTTTGCCGATTTGCCCGACATTTTTCAATTTCGGCAATTTGC
+CGGTTTGGCGATTTGCCCGAAATTTTTCAATTTCGGCAATTTGCCGGTTT
+GCCGATTTGCCCGACATTTTTCATTTTCGGCAATTTGCCGGTTTGCCGAT
+TTGCCCGAAATTTTTCAATTTCGGCAATTTGCCGGTGTGCCGATTTGCCA
+AAAATTTTCATTTTCGGCAATTTGCCGGTTTGCCGATTTGCCGGAAATTT
+TCATTTTCGGCAATTCGCCGGTTTGCCGATTTGCCCGAAATTTTTCAATT
+TCGGCAATTTGCCGGTTTGCCGATTTGCCGGAATATTTCATTTTCGGCAA
+TTTGCCGGTTTGCCGATTTGCCCGAAGTTTTTCAATTTCGGCAATTTGCC
+GGTTTGCCGATTTGTCGAAATTTTTCATTTTCGGCAGTTTGCCGGTTTGC
+CGATTTGCCCGAAATTTTTCAATTTCGGCAGTTTGCCGGTTTGCCGATTA
+GCCCGAAATTTTTAAATTTCGGCAATTTGCCGGTTTGCTGATTTGCCAGA
+AATTTTTCAATTTCAGCAATTTGTCGATTTGCCATTTGCCGGAAGTGTTC
+AGAAGGATTTTTTTATAATAAGGAACCACTTAAAACTGTGCCGTTTTGAA
+ACTTTTCCCCGTTTTTTTAAGATGATTTCATAGAATTTGCTTACTTGGTT
+TGCCGAATTGCCAGAAGTTTTTCAATTCCTACAAGTTGCCAATTTGCCGG
+AAACTTTTTAATTATGGCAATTTGCCGGTTTGCCGATTTGCCAGAAATTT
+TTCAAATTCGGCAATTTGCCGGTTTTCCGATTTGCCGGAAATTTTTCAAT
+TTCGGCAATTTGTCGATTTGCCGGAAAATTTTTATTTATGGCAATTTGCC
+GATTTGCCGGAAAAAAAATCGTTTCCCGCCCACCCATCAGTTGATGAGTT
+CATCTTTTTTTTGTGTCTCTCCCATCAATCTTAAACTCGACCCGGACTGG
+CAAACGCATATCTACAGTTTTCTCTTCTTAAAATGGTGGTCTTAAGTTTC
+GAAGACTATGCGTAATTTCTAGCGAAGTGGCGAATTTATGATGATTTTGC
+AATTTATCAATGAAAAAAACAAAAAAAGCATTTCCGCGTGGCAAATTATC
+ACTGTTGTGCCGCGAATAGTACTGATATAATTTTTTTTTAAATTGAATCA
+GTTTGGAATTTCGAATTTTTGAAACAACCGCCGGCAAAATGAATAATATA
+CTGTGAGTTTTCAAAGATTGTTCCCCGGTTTTCTTGTAGATTTTTGTGCA
+ATTTCAAAATTTCGACTTTCAGCGGAAACAAAAATACAAAAAGGTCGAAG
+AAGAAGGACGGAAAGTTTACGAGCAACACTGCTACTGATCTTGTTGAGGC
+CCCAAAACCAGGTGGAGCAAAAGGATCCAAAAAACCAAAACCATCGAAAG
+GAAATGACGACAGGGGACGCGGCGAACCGGAAATGACTGCACAATCCAAA
+AAAACCAAGAAAGCAAAAAAAGTGAGACAGAAGAGAGATACAAAGGCACC
+GGTGAGTTCAATTTTATAGTTTTATAGATATAATTGTATCAGGGGTGGGC
+GGCAATTGCCGTTCGGCAAATTGATTTGCCGCCAAATTCGGCAAATCGGC
+AAATTGCCGGTTTGTCGATTTGCCGGAAATTTTCAATTCCGGCAATTTGC
+CGGTTTGCCGATTTGCCGGAAATTTTCATTTTCGGCAAATCAGTTTTGCC
+GGAAATTATAAGACGGAAACACTGTCTTTTTGAATTGTTCCCGTTTTTTC
+TACATATTTTCATAGAAATTCATAGAGACAATTTGCCGAAATTTTTCGGC
+AAATTGCCGTTTTTCCGGCAATTTACCGATTTGCCGGAAATTTCCATTCC
+GACAATTTGCCGATATGCCAATTTGCCGGAAAAAATCGTTTGCCGCCCAC
+CCCTGAATTGTATCCCTTTTTAGTCTCCTGCAATGTCACCTCGATCACGT
+GAAATGCTGTCAGACAACAAAAAGACGACCGTTGAGGATGATCCAGCAGT
+TCCAATAACAACAAGTGTCGCTGGAGCAGTCACTTCTACGATTCCTGCTC
+TCATGTCCACTGAAAACGCGTTTCAGCCACCCAAAGACCTTATCTCGGGA
+AGAAAGCCAAAAGGTGCTCCGAACTTGTCTGGCAGCGTTCCACTTTCACA
+CAAGAGCTCACTGACTGGAGGTGCAGATAAGTGGGTTGGAGAAGCCGTGG
+CAAAGAATTGGATGGATTCGATCGGTTAGCATCCTTTTTTTTTTGATTGG
+AGGCCCCGGCGGCGTAAAAATCGTGCCAGAGTTGCAAGAGTGGGCGTTTT
+TTTTTGTTTTTCTGTTGTTGGTGGGGCCTTATTATTATTTGGTCGATGGT
+GATTTTACTTTACTGGTGGAAATCCGCTAATAAAACTAAAAACATCGGGA
+TATAAATAAAAACCCAACTTTAAAAAGCGAACCAATCAGCAGTTTGCTCC
+GCCCACTATTCAACCAATCCAATGATTGGTTCGAAATTGGGTACTCATTT
+TAGAGGGAATTCAAACGGAAGATTAGCAAGTTCGGTTATTGTTTCATTAG
+AATATCATTGCTTATATATATATTTAAAAAATAGTGTACGTCATCAATGG
+GCGGAGCCTCTCCCATCGTGGTGAGACCCATCGTGGTGAGACACATCGTG
+GTGAGACCCATCGTGGTGAGACCCTTCGTGGTGAGACCCTTCGTGGTGAG
+ACCCATAGTGGTGAGACCCATCGAGGTGAGACCCTTCGTGGTGAGACCCA
+TCGTGGTGAGACCCATCGAGGTGAGACCCTTCGTGGTGAGACCCATCGTG
+GTGAGACCCCCATTAATTTTGGCGTGAAATTCAAATTTTCTAAGAACAAT
+TTTTTGGCTTTTTTTTTAAAGAAAAATCTGGAAAATTCTAGCATTTTTTT
+AGAATAATCTGGAAATTTCTTGAACTTTCTAGCTAAATCTGGAAACTTCT
+AGAATTTCCTAAAATAATCTGGAGACTTCTAAAAAAGATCAGGAAATTTC
+TAGAACTTTTTTAGAATCTTCTGAAAACATCTTTCTAGAGTATACTAAAA
+ACTTCTAGAATTTTCATAAAATTCCGCGAAGCTCGAGGAAGAGATTTGTT
+CAAACAATTTAATGTGGAGCCAGTCGGAGCACGCGCTTTGCGCGTGCGAA
+CGGCTGGTTTTAGATATTTTGTAGTATTTTTCAAATCTTAAATTTTCAGA
+CACAGCAGAGGTGAAAAAGGAATACGATAAACTGCAATCACAGAAAATCG
+ATGTGGAGAAGGACTGTAAAACCTGGAAATCCAACCCAAAATTTAACCAA
+TCGGAAGACTTTCCTGCCTTGGACTCCAATCTCGTGAAACTTGGCAAAGA
+CTATGTGAACATCAGTCTTGTAGATGTTCCATTGGGAAGAAATGTTCATC
+TCGGTCAAGCTCCGGTCACGAATACGGAAGAAACATTCTGGAAAGCTGTG
+TTCGACAAGCGAATCACTCACATTGATCTACTCGTCGGCGATGAAACCAT
+CGAATTCTTCCCTAAAAAGGCAGAAGATTATACAAATTATGGTCAGATGT
+GGATCAATAACCGCCGTGTCGAGTATGTCAATGACGATGTGTACCGATTT
+GCAATTGAAGTAGTGCCCCACGGATGCTCCAACTCGATCATCTGCAATGT
+GACTGTTATCAGCAATTGGAAAGTGGACACTGTGCCTTTGAAACAAGCAA
+TCGCCATCAAAGAGGCACTTGGTCTAAACTACTTCTTGCTGAAAGCACCC
+GCTGACGAGCATGCGATGATCGTCTCACCACGTGGAGCTGGACGAGCTGG
+CTACTTTTTGGCACTTGCGGTTGCAGTCAACACAATTGATACAAAGCTTG
+CCGAACCATGTATTGCGGATATTGTCAAATCGATTCGCTCCCAGAGACCA
+AGAGCCGTGGATTCATTTTGTCAGTACTGCTCCCTGTACATTTCGTTGCT
+CTACTTCATCAAGGTATTGGTTTTTGAATTCTTGTAAAATGAGAGAATAA
+TTCTCAAATTTACAGAAGAAAGTGACAAAACCAGCAGAAGGGGATAAAAA
+GCCAACACTGAGCAACAAATACATCTACAAGAAGTCGGTTGAGTTGACCA
+AGCAATTCACCGTTCTCCTTCTCGAAGCGAGTCAGCAAAGTGTGATGGGA
+CCTGGATAGTTCTTCTCCATTTTGAATATGGAAAAGCATTTGAAGTGATC
+TGGGTTTGAAAATGAAGAATTTTATAAACCCTGGATTATTTCCGAAATCT
+TGCTTCCTGCCTGCTGTCTCATTGCGGCTTGATCTGCAAAAAAAGCGGTA
+ATATCTCCCCCAGGAAAATGTGACGTCAGCACACTCTTAACCATGCGAAC
+TTAGTTGAAACGTCTGCGTCTCTTCTCCCGCATTTTTCGAAGATCACACC
+AAAATGGGATACTTTGACAACACGTGCCTGCCATCGCTTCCTGACCGGGG
+ATTTTGTTAGAAAATTCGTGGAAAATAGGAAGAAACATTTCGAGAAAATG
+GAATTATTGATTTTCTGATTTTCTCAAACAAAAAAAAATTAAAATCGATT
+GATTTCTGGCTTACCTTACCTAAATTGAAATGGAAGAGTTTGCCGAACTA
+GGCCATTTTGGCTCGGCTATATCTGGGGTATATTTACGGCGCGTTGCGTG
+TCGCGTCGCGGCTCGATTTTAGTTGTAAAACTAAATGTGATTTGTCCGTG
+TGGAGTACACGACTTTCACATGCGTTGTGCGGCGGGCGATTGTCAATGGA
+GCGCGAAAAATACAATGAGGAAGGCCAAAACCCCGTGTATTGATTTTTCG
+AAAATTTCGGAAAAATCTCTTTGTTTTATTCATTATATTTCTCCTAATTT
+CTTTGAAATGTTCAAAAAATCTGATTTTCTTTTTTTTCCCGAATTTTTGA
+AAAATCGATATTTGCTATCCATATTTCTCGAAAAGAAAATCGATTTATTA
+ATTTTTTTCCGGTTTCCTGGAAGCTAATCAATTCAGAAAAAAGAATTAAG
+CTATGAATATATACTTATAAAAGTCGTAAAAGGTATGGAAATATAAATTA
+TTTTAAAACAGCGATTTCTGACTGAAGCATCTCAACTACCAGGGCCTCAA
+GTTCTTCTTATCCGACAAATGAGACGAGTCGGAGCTATAATTGTGCCGAT
+ATTTTCCGGGCGCCGTCTCTTCGAACTCGGATACGGTAGCCTGCCCGACG
+TATTTGAAATCGCCCATTAGCACTTCGTGGCAAGCGCCGATTGATGCTCC
+GTGGCCGACGAGTAGGAGGTTTCCTGAAAGAAAATCGATAATTTGCGGCG
+TGTTTTTATTGATTTTTATGTGAAAATTGGCAAATTATTGATTTTTCGGC
+TGAAATCATAAATTACTGATTTTCTGTTAAAATCAGTAATTTATTGATTT
+CTTCGGCTAAAATCAGAAATTATCGATTTTTCTGTGAAAATCTGAAATTA
+TTGATTTTTCTGCGAAAATCAGAAATTTACGTAGTTTCGCAAAAATTACC
+TTCATATTTCTCGAAAATCGCCCGCAGGGTCTTTCCGACACGTGGCACAC
+ACGCGTCATCTCCACATCCTTCGCGGGGTAGTGTGTACTGAAAAAAAAGT
+TCGGTAATTTTTCTAGGTCTCGCAGCGATTGCCGCCACCGGTATATTTTC
+ATTTTTCCAACTATAGCGCCAGCACCGGCGCCGGCATCTTTTTATTTTTC
+CACGTAGCACGTCGGCGCCGGCAGCCGCGCAAACTATTTTCGCCGCCGCC
+GGCATCTTTTTATTTTCCACATAGCGTGCCAGCGGCGCCGCCGGCATATT
+TTTATTTTTCCACGTAGCACGTCGGCGCCGGCAGCCGCGCAAACTATTTT
+CGCCGCCGCCGGCATTTTTTACTTTTCCACGTAGCGCGCCAGCGGCGCCG
+CCGGCATGTTTTTATTTTTCCACGTAGCGCGCTAGCGCCGCCCCCGGCAT
+CTTTTCATTTTTCCACGTAGCGCGCCAGCGCCGGCAGCCGCGCAAACTAT
+TTTTCGCCGCCGCCGGCATCTTTTTATTTTCCACATAGCGTGCCAGCGGC
+GCCGCCGGCATATTTTTATTTTTCCACGTAGCGCGCTAGCGCCGCCGCCG
+GAATTCATTCATTTTTCCACATAGCGTGCCAGCGGCGCCGCCGGCATCTT
+TTTATTTTTCCACGTAGGGCTCTAGCGCCGGCGGCATTTTTCATCTTTTC
+ATGCAGTGCGCCAGCGCCGCCGCCGGCATCTTCTCATTTTCCACGTAGCG
+CGCTAGCGCCGGCGGCAGCGCAAACCATTTTTCGCCGCCGCCGGCGCCTT
+TTCATTTTTTAATTAGTGCGCCAGCGCCGCCGCCGGCATCTTTTGATTTT
+TCCACGCAGTGCGCCAGCGCCGGCAACGGCGCAATTCTAATCTCGGTCTT
+TTTTGAGCGATACCTTCGAGAAAACAGGAATATAGTCCAAATCAACAAGC
+GGAAATTTCTCAGCTAGTTTGTCGGTTTCCCAGAATCCAGGAGGCTTATC
+ACAAAGATAAAGTGCCTCACAAAGGCCACCGTCCGCCTTCACTTTCATTC
+CTTTATCCTCAATAATCGTCGAAGCTGTCTCAATTGTCCGATCGAACGGC
+GAGGCAAACGTATGCGAGATTTGTGCATTTTCGAACCGATTTTTGCACTC
+TTTCGCCTGTTGCCGACCGCGCACGCTGAGCATCGAATTGTCCGACGTGA
+GACCGTCGGCTCCGTCGAGTTTACGCCAATTTCGATTGATATTGTCCTCG
+CTGCAATGCAAAAAATCAATAATTTCTGATTTTCACCGTAAAATCAATAA
+TTTCTGATTTTTGTTGAAAAATCATTACTACCGATTTTAACTGAAAAATC
+AATAAATTCAGATTTTCATTTTTTTTTTCGAAAAGTCGATAATTTCCAGA
+TTTTCATCGAAAAATCAATAATTTGTGATTTTCACAAAAAATCAATAATT
+TCAGATTTTTACCGAAAAATTGATAATTTCAGATTTTCACCGAAAAATCA
+GAAATTATTGACTTTGGATAAAAATCAATAATTTACTGATTTTCATCGAA
+AAATCAATAATTTCAACCTTTCGCAGAAAAATCGATAATTTTTAATTTTC
+ACCGTAAAATCAATAATTTCTGATTTTCACCAAAAATTAATAATTTTAAT
+TTTTTTTTCGAAAAATCAATATTTTCTAATTTTTATCGGAAAATCAATAA
+TTTCCGATTTTCACCAAAAAATCAATAATTTCAGATTTTTATCGAAAAGT
+CAATAATTTACGAATTTGACAAGAAAAAATCAATAATTTGCTGATTTTAA
+CAGAAAATCAATAATTTTTGTTTTTCATTGTTTTTTTTTTCGAAAAATCA
+GTACTTTTTTAATTTCCCCAAAAAATCAATAATTTTTGATTTTATTTTTC
+GAAAAATCAATAATTTCAGATTTTAACCGAAAAAATCAATAAATTCAAAA
+AATTTCATTTTTTTTTTGAATTCTTAAAAGTACCGTTCCGCGTGTCGAAC
+AATCCAAATTTTCCGTGGATAAGTGATCGGCATCCTATCGAGATCGGTTT
+TAGCTGAAAAAAAACCTTAAAAAATTGGAAAATTGTGTACTCCTCTCGGA
+CACGTGGTGTCAGGCTCTCCCATTACGGCTTGATCTACAAAAAATGCGGG
+ATTTTTCGTTCTTAACCATACGAAATAAGTTGAGAACTCTGCGTCTCTTT
+TCCCGCATTTTTTGTAGATCAACGTAGATCAGACCAAAATGAGGCACACT
+GAATGAAGACACCAGGATTTTTCGAAAAACTCTAAAGAAATTCTGCAAAA
+AGTGACGTCATGAGGTATATAGGTATGAAATCGAATACTTGGTATCAAAT
+GACGGAAAAATAAACGAAAGTTGCAAAATTTTTTGATGGAATTTATTAGA
+CTTTGGCGGGAAAACAGATCAAATTTACATTAAAAAATACGGGAAAAATA
+CGGGGAAAAAAACCAAATTATTGCCTAAAAAATTCAGGATTAAATTGCGA
+GTTGTACTTTTTCTTCTTTCCACGCTTCTCCTCCGAATCCTCGGCGGCTT
+TTCGTTTCTGCAGCAGCTCAATTTCCTCGGGATGTAGCAAAGCATGGGCT
+CTCGCTTTCTCGACTCGTTCCCGTTTCAGACGCTCGTCTCGCATGCTCGC
+CAGCTTCTGCCGTCGTTCTCGATCGTATTCCTCTTCGAGTTGACGTTCTT
+CAGAGCTATCACGGTGGCGGTGCTTTTCTGGAAGAAAAATTGGGGGGTTT
+TTTTGTAGTTTGTAGTGGTGAGCACCCTATATTGGAGGCGCGAAAAAAGA
+GATTTTTCGAATTTTTTTGTAGATCAACGTATGGTTAAGAACGTACTGAC
+GTCATATAATTTTGGGCGAAAAATTCCCGCATTTTTGGTAGATCAAACCG
+TAGTTGGACAAAAAGCAGATTTTTCGAAAAAAAATTACGAATTTCTGGCT
+TTCCTCATAAATTGAAATGGAAGAGTTTTTGCCGAACTAGGCCATTTTGG
+CTCGGCCATATCTGGGGTAGATTTACGGCGCGTTGCGTGTCGCGTCGCGG
+CTCGATTTTAGTTGTAAAACTAAATGTGATTTGTCCGTGTGGAGTACACG
+ACTTTCCCACGCGTTGTCCGGCAGGCGATTGTCAATGGAGCGCGAAAAAT
+TCAATGAGGAAGGCCAGAACCCCGTGGTGGTTCGATGCACAAAACTGATT
+TTTTTTTTGAATTTTTGGGATTGCGCAAGAAATTTCGCCGAAAAAGTCGA
+TAACTCAAAAAATTCTAAAAAATTTGGATAATCTGGAGAAAAAACCCAAA
+ATTTGCTGAAAATTTCGAAAAATTTAGCTTTAAATTTTTGCGCATGGCCG
+CCGGAAAAGAAAAAAACTCGGCCACCAATTTTTTGGCGGCCATGATGCAA
+GACACCATATTTGACGCGCAAAAAAAGGTGTTTTTGGATGTTTTTTTCTT
+TTTCCGCCAGAATTTTTAATAAATTTCCAGGGACAAAAAATCATAACCTG
+TTGCAAAAATGTTTTTTTTTTCGAAAAATTCAATTTTGCGCGTCAAATGT
+GATGCTTTAAGCTCTGTGGCCGCCGAAAAAGAGAAAACTCGGCCACCAAT
+TTTTCACTCTCCATTGACAATAGCCTGCTGGACAACGCGTGGAAAAGTGT
+CGTGTACTCCACACGGACAAATACATTTAGTTTTACAACTAAAATCGAGC
+CGCGACGCGACACGCAACGCGCCGTAAATCTACCCCAGATATGGCCTGGC
+CTAGTTCGGCAGAAACTCTTCCATTTCAATTTATGAGGGAAGCCAGAAAT
+CCGTGGCCGAAAAAGAGAAAACTCGTCCACCGATTTTTTTTTCTGACGGC
+CATGACAAGTTTGCGCGTCTATAATACATCATATTTGACGGGCAAAAAAT
+TTTTTAAAGTTTTTTCGAATTTTTGTGATTTTCGAGCAGAAAAAAAAATT
+GTCTGAAAATTTATGTGGCCGCGGTAAACTTCGGCCACCGATTTTCGACG
+ATTTTGCCCGTGTTTTTGACGGAAAAAGCACCATATTTGACGCGCAAATT
+TTCAAAAAAAAAAAAGCCCAAAAATCGCACTTTTCTTCTTCTTCTTGTCT
+TTTTTATGCCGTTTCTTCGCCTTTTCTTCACTATCACTATCCTCTCGTTT
+CCGCTTCCTCTCCTCTTCCAGCTCTTTCCGCTTCAAACACGGCAGAGCAT
+CGCGCGCTTTTCGTCGATCAAGTGGCTCGGCGGCTCTTCGCAGCGGCAGC
+TCCTCGTACCACTCTTTTTTCTTGTTTAAATCGTTCGTATTATCCGCGAA
+ATACACCTGAATTCCCATTTTCGACTCCCATTCCTTCTTCTCGGCAGCTT
+TTTCCGCTTCGTAGTCGCGGTTTCCGGATCCATAGTTTTTTCGTTCTTCA
+CGTTCGAGATCCTGCAAAATATCGATTTTTTTTGGAGAAAAATATAGTTT
+TTTTTTGGAGAAAATTATCGATTTTTTGGAAAAAATTATCGATTTTTCGG
+GGAAAATTAACGATTATTTTAATAGAAAATTATCGATTTTATTTGGGAAA
+AAAATCACTGATTTTTTGGAAAAAATTATCGATTTTTTTCGGAGAAAAAA
+TATTAAATTTTTTGCAGAAAATTATCGTTTTTTTTTTTGAAAAAAATTAC
+CGATTTTTCAGAGAAAAATATCGATTTTTTAGAATAAAATTATGGATTTT
+TAAATATAAAATTATCGATTTTTAGGGAGAAAATTATCGATTTTTTTTGG
+AGAAAAATATTGTTTTTTTTTGGAGAAAAATATAGATTTTTTTGAAGACA
+TTTATCGATTTTTTGTTGATAAAATTATCGATTCTTCGGGGAAAAATATA
+GCTTTTTTTGGATGAAATTATCGATTTTTTGGGAGAAAAAATACCGATTT
+TTTTGGATAAAATTATCGATTTTTTTGAAGAAAAAGTATCAAATTTTTTG
+AAGAAAATTGTCAATTTTTTTGGAAATAAATATAGTTGTTTTGGATAAAA
+TTATCGATTTTTCAGCTAAAAATATAGATTTTTTTAGATAAAATTATTGA
+ATTTTAAAAAGAAAATTATCGATTTTATGGGTAAAAAATAACGATTTTTT
+TGGAGAAAATTATTGATTTCTTCGGGGATAAATATTGATTTTTTCGGGGA
+AAATTATCGATTTTTGGATAAAATTATCGATTTTTTGGAAAAAATTATGG
+ATTTTTTTTGAAGAAAAATATTGATTTTATTGGAGAATAATATCGAATTT
+TTTCGGGAAAATATCGATTTTTTGGAGAAAATTATCGATTTTTTTTGAGA
+AAATTATCGATCTTTTGGGTAAAATTATCGATTTTTTGAAGCAATTCTGA
+GCCAAATTTTGAATTTTCGAGCGGCAATTTTTGCACAAAGCATCATATTT
+GACGCACAAAATTCGAATTTTTCAGAATTAGTTTCACAAAAAATCCATCT
+ATCACCTGAAACAAGTTCACATGTCCCGTTTCATCTGAAATGCTGACATC
+TTTTGCTGCTCCAGCTGAGCTCGAACCAGCTCCTCCACTAAACATCGTCT
+CCATTCGTTGATCGGCTCGGGCTCTCAACTGCATCAGGCGCCGCTCGTTT
+TCCGCCTGAATTTGCCTGTCGAGCACACGCTGCTCATCTTCGGCGGCTTT
+TCGCTCGTCTCGGCGAACCCGTTCCATGTTGGATTTTGTCCGAACGTGCC
+ATGATTTGTGATGGAGAATGTTCATCTGGAAGCGGAAATTATAGAGAAAA
+AATTGATAATTGTGCTCGAAATTTGGCTCTGGAAGAAGCGCAAAAAATCA
+ATAATTTCGTCCAAAAATCTATTTTTTTCAGAAAAACCAAAAAGCGTTTT
+TTTTTCCAAAAATAAAGATAATTTTCGTCCAAAAATCGATAATTTACTTC
+TAAAAGTCTCAATTTTTCCAACAAAAAAAACAATTTTCGTCGAAAAACCG
+ATGTTTTCAGAAAAATCAAAAATCAAAAAAAAAATTAAAAAATTAAAAAA
+AAATCAATAATTTTTTCTAAAATCTTGCAATTTTTTTCTAAAAATCGTTT
+AATTTTCTTCTAAAATCGATATTTTTCCGGATTTTTTCGTGAAAAAAATC
+GTCAATTTTATTGAAAATTTTGCTAAATTTCGAAAAAAAATCTTGAAATT
+TCGATGCACCATGATTTTGAAAATTCTGCTCCGGATCAATTTTTCGAGAA
+AAATTATCGATTTTTGGAAACTATCATACAAAAATCGATAATTGTGCTCG
+AAATTTGGCTCTGGAAGGAGGAAAAATCAATAATTTTCTTCTAAAAATCG
+ATTTTTTTTCCAAAAAATCAATAATTTCGTCGAAAAACCGATGTTTTCAG
+AATAATCAAAAAAAAAATTAAAAAATTAAAAAAAAATCAATAATTTTTTC
+TAAAATTTTGCAATTTTTTTCTAAAAATCGTTTAATTTTCTTCTAAAATC
+GATATTTTTCCGGATTTTTTCGTGAAAAAAATCGTCAATTTTATTGAAAA
+TTTTGCTAAATTTCGAAAAAAAATCTTGAAATTTCGATGCACCATGATTT
+TGAAAATTCTGCTCCGGATCAATTTTTCGAGAAAAATTATCGATTTTTGG
+AAACTATCATACAAAAATCGATAATTGTGCTCGAAATTTGGCTCTGGAAG
+GAGGAAAAATCAATAATTTTTTTCTAAAAATCGATTTTTTTTCCAAAAAA
+TCAATAATTTCGTCGAAAAACCGATGTTTTCAGAATAATCAAAACAAATT
+TCAAAAATAATAAAAAAATCAATAATTTTTTCTAAAATTTTGCAATTTTT
+TTCTAAAAATCGTTTAATTTTCTTCTAAAATCGATATTTTTCCGGATTTT
+TTCGTGAAAAAAATCGTCAATTTTATTGAAAATTTTGCTAAATTTCGAAA
+AAAAATCTTGAAATTTCGATGCACCATGATTTTGAAAATTCTGCTCCGGA
+TCAATTTTTCGAGAAAAATTATCGATTTTTGGAAACTATCATACAAAAAT
+CGATAATTGTGCTCGAAATTTGGCTCTGGAAGGAGGAAAAATCAATAATT
+TTTTTCTAAAAATCGATTTTTTTTCCAAAAAATCAATAATTTCGTCGAAA
+AACCGATGTTTTCAGAATAATCAAAACAAATTTCAAAAATAATAAAAAAA
+TCAATAATTTTTTCTAAAATTTTGCAATTCTTTTTTCTAAAAATCGATAT
+TTTTCCGGATTTTTTTCGTGAAAAAAATCATCAATTTTATTGAAAATTTT
+GCTAAATTTCGATAAAAAAACGATTATTTTGAAATTTCGATGCACCATGA
+TTTCGAAAATTCTGCTCCGGATCAATTTTTCTAAGAAAATTATCGATTTT
+TGGAAATCATCACACAAAAACCGATAATTTTGTGAAAAAATTCGATTTCG
+ACGCACCATGATTTCGAAAATTCTCAGAATTTTAGAAAATTTATCGATTT
+TGTGTAGAAAAAATTCGAATTCCAGTGGAAAAATTTTCTTTTCTCAAAAA
+ATGTTTGATTTAAAAAAAATCGATTTTTTCAGAAATTCAGGCATTTTTTT
+GCAAAGTAAATTGGCAAAAATCGATGATTTCACTGTGAGAATGGGAATTT
+TTGTCAAGAAAAATATAAAAAATTGCCTTAAACAATTAAAGTGGTTGTCA
+AAAAATTGAAATTTTGGAAAAAAAAATATATTTACAGATGAATTTATTAG
+AAAAATTCCACAAAAAAAGAGGTTCCATCTAATATTATTATGTCGCATTG
+GGGGTTATATCACATAATTTTTTTTTGTTTCGGTTGCCGTGGAGAAGGGG
+GAAAATATCACATTTTTCAGAGGAAAATCACAATAAATATAAGGAAAATT
+TACAAAAAAAGGCGCGGGGGGAAATTTCTTCACAAAATTATCGATTTTTG
+GGTGATAATTTCCAAAAATCGATAATTTTTATAGCAAAATTGATCCGGAG
+CAGACTTGGGATAAAGCAATTTTTGGAGGGGGAAAATGAACAAATTAATA
+AAATATAATATATTCGGGGCAAAAAATGGGAAATAATTAAATTGTCGGAA
+CATATAAATGATTAATTGATTGAGCCAATGGCATTGGTTTCATGTGAGCC
+AACGCTTCATTACAGAACACTTCCTCCCGATGACGTAGCGGACGAGAATG
+CTCGACACGAGCAAGACGGTAGGCTCTAGAGGCGTTTATCTGGAAATTTT
+TAGTGAAAAAATGAAGAAAAAAAGCTTTTTTCGCTGAAAATTCCAAGATT
+TTCGGTTTTTTTTTTGCTAATTTTTTTTAAATTTGCCTTGAAATAAATTT
+CCAGATGTTCAGTAGTTTTTTTTTCCTTCAAAAATCGATTTTTCAATTAA
+TCAAACATTTTTCAGAGTATTAATAATTATTTTTCCACCAGAATTTGAAT
+ATTTTATCCAAATTCTGAGAACCGGCTCACAGAGCGGCTTTTACTACGTG
+GCCTAGAAAAATCAAAAACTCGGCCAATGATTTATCTGGGATTTTTGACG
+TGGGATGTTTCTGAAACTTGACGAGAATGTTCTCGAATGGGGGTTCTATA
+GTTCCACCGTGGCGATTTTTGAGAAAATGTTCCGTATCCATGTTATGAAG
+GTGGCCGAGTTTTCTTATTTTACGGCCACGTAATAAAAACCGCTCTGTGG
+GCTCCTGAGCAGAATTTTCGAAATCATGGTGCATCGAAATTTCAAAATTA
+TCGATTTTTTTTTTGAAATTTAGCAAAATTTTCAATAAAATAAGAAATCA
+TGGTGCATCGACAAACCAATTTTTTCCATTTTTTCGGAATTTAAAATAAA
+ATTTAAAAAAAAGTAAAATTCTGGAATTTTACTTTTTAAAAATATTTTTT
+TCAAATTCTGGCAGTTTTAAAATAATAAAAAAACGTTTTTTTTCCATTTT
+TTTCAAAAATTTTTTTCTGAAATTTAGTACTACAAATGTAAAATTTACAG
+GGTTTTCACAGGAATTTTCAATTTTTTTGATTCGCTTTTCTTCAAAAATT
+CTAAATTTTCAGGTTTTTTTTTCCAATAATTTTTAATTTTTGTGAAAAAA
+AAATGTTTTTAATTTTTTCAGACTTAAAAAATTGTGACAACTTTTTTCAA
+TTTTTTCCGCAAAAATAAATTTTCGGAAATTTCAAATTTCCTACAAAAAA
+CCCCTTACCACAGTAAGCCTAACCAACTGTGAGAGCTCGCTCATCGTGAC
+TAGGGCTCCGTCGAAAAGCGGCCCAAACTCCAGAGCCGACGCCGTATCGA
+CGCGCACTCGAACCATCTGAAAAACCAAATAATGGAAGAGTTTTTTTTCG
+GCCAAGCCAGGCTGCCCCATTTGATCTACGTAGATCTACAAAAATTGCGG
+GAGAAGAAAAAAGAGACGCAGAGTTCTCAACTGATTTCGCATGATTAGGA
+GTGTGTTGACGTCACATTCGCAAAAAATTCCCGCATTTTTTGTAGATCAA
+ACTGTAATGGGACAGCCTGGGACCACGTGCAGTGTTAGGCTGTACCATTA
+CGGTTTGATCTACAAAAAATGCGGGAATTTTTTGCAAATGTGACGTCAAC
+ACACTCCTAATCATGCGAAATCAGTTGAGAACTCTGCGTCTCTTTTTCTT
+CTCCTGCATTTTTGTAGATCAACGTAGATCAAGCCTCTCTCTCTCTCTCA
+CCTTATCACCGACTTGCTCCAACACAATCAGAACATCACAAAACTTGGTG
+GCAATCGTTTCGCGGGTGTACACTTTCCGTGTGTTCTCAGTCCACACCAC
+ATGCACCTCATCGTTTCCGATATGCTTCCACTTCTGCTGCACATCGCCGT
+TGAGCATCGTGCTCACATGGAATATCACCTCAGCCTCGGCGTCTGCAAAG
+TACGGAGCCCGTGTCTCTACGGGCAGGCCACCGGTGTAACCATCGTGTCC
+TCGACCCACTTTGACCTCCCATCCGAGCTCCGACGTGAAGCTGTCAAATT
+GCGCGGAGGCGGAGGCGGTGGTGTTGGACAGGATCGATGCTCGATCTTCC
+TGCGATTCTCCTACATAGATCACAGCGACTTTGTGGACTTCACGAGAAGA
+AGTCTGATCTAAATGCTTCAAGTCACGCGGGAAATTCGCGTGAACCTGAG
+ACACAAGTGGGACGAATCCCAGGGAAGCCGACAGCGATCTCCATTCGAGA
+AGCTTCGCGTTCGGAGTGAACGCTGGCAAATGATCGTGAGCCGCCGACGA
+TGTGCCAAGTGGCTGTGGCTGCCGTCTAGACGTCTCAATCATCGATGTAA
+ACTGTGCGGCACCATCGACAGGCGACGGGCTCCCACGTGACGGGGGGTAG
+TCCGGTAGATCATCGAACGGATCATCCATCGCTCCGAGGATCCCCTGGCT
+TTCCCGACCGGGACGTTTTCCCTTGAGAGCCTCTTTGCGTAGCCAATTGG
+TCACGTTGGTGGCAGGCTTGCGGACATCCTCATGGGTATCTAGATCCCAG
+ATATGCCGGCCAACTACCGTTCGGGAAGTGATTTCGCAGGGGGATTTGGC
+GTGGAAATCCTTTCGGGACACCGAGATAATCGCCGATTGCCGATTAATAT
+ACACGGTTTTATCCTCTCCTTGTAGTGGCGGTGCTCCTGCAGAGCTCCAT
+CTCTGAACCTCAAAACCTCGCACCGGATACTGACCACCGAGCGTGACAAG
+CTCTCCATGGAGCACCATATGCCTATCGGCCAAGATACCGCGAATGACGA
+GTGGCATTTGAGGTTGTGGCCATTGCATACAAAGCTTCACCATCTGCCAC
+TCGATCTCGGTTCTCGTACGCTCATCGCGTAGGAGCGAGGCGGCACGGAG
+CAGCGCCTGGAGCAGTGTGGTGCTCGAGAACTGGGCGAGCGAGGCGATCG
+ACGAGCAGAAGAGCGGAATGAGCCGCATCGCGAACTGATGGGTTTCGATG
+GTTTTCAACGCGGTGAGCACCAAGTCGATTTGGGCTTTTTGCACGATGAG
+GATGGCTAGCGAGTTCACGATTACTACGGCGTTCTCCGATACGTCTGTAT
+TGACAAGCTGATCGAGAAGGATTTGCTCGGCTCCAGGATACGATGAAGCT
+AGCATTGAGAACAACTTCAACGAGTTCGAGGACACCTTCGTGTCCTTCGA
+GCTCTTCGCCGCCTGCAACATTTTCGGCAAATGCTCCAGAGCTCGCGGAG
+CAACAATTGATAGTTCGTGTGCAGAGAGCCCACAAATCGCCGGAACCACT
+AGTTGCTCCTTGGATTGCATAAGACGGATGAAGCAGAGAAGAATGTTGGC
+CGAGAGCAGTGGCGGTGGCCGACGGATCGTTGATTCGTTGAGAATTGCAC
+TTAGAGCCGGAACACAGCGGGGCAGCAGGATTGGGGGTACGGTAACGAGG
+CGGCACGCGAGCCAGTGGGCCAGTGGGTGCAGGTTTACCTGGAAAGCAAA
+ATTTTTTTTGGCTTTTTTTCAACTCGAATTTTTTTTCTAAATTTTTTTGT
+AAATTTTCTAAAAAATAATTGTTCGATTTCAGAGTGCCTCATTTCGTGCG
+TGATCTACGTTGATCAACAAAAAATGCGGGACTGATTCTGCATGGTTAAG
+AACGTGCCGACGTCCTATTTTTTGGGCAAAAAATTCCCGCATTTTTTGTA
+GATCAAACCGTAATGAGACAGCCTCACGTCGTGCCAGAAAGTCCCATTTC
+GTGCTTGATCTACGCTGATCTACAAAAAATGAGGGGCTGATTGTGCATGA
+TTAAGAACGTGCTGACGTCACATTTCGTTTGGCAAAAATTCCCCCATTTT
+TTGTAGATCAAACCGTAATGGGACAGCCTGACACCACGTGATCTTCAAAT
+TCCCGCCAGCCTGAAACCCACCAAAAGCAAGTTCTCAATCGTCAATGACA
+TGCAATCGATTGCCACGTGGGCACTCGAGTTGGTATACGGATCCACGAGT
+GAGATGACACGACGCCACGTTTGAAGCCACGCCAATTTGTCGCCAGACCA
+AGACTGAAAAAGGGAAAAAGTGTGATATGCGCCTTTAAGAAAGGGTTACT
+ATAGTTGTCAACAACAGAAAAAAATGCTGAAAAGGCATTTTTCAGGGTCT
+ATTTTCACAATGAGTTTGGGTATAAATTGGAGAGTTTTCCATAGATAATG
+CGTACTGCGCAACTAATTTGACGCGCAAAATATCTCGTAGCGAAAACTAC
+AGTAATTTTTTAAATTACTACTGTAGCGCGCTGGTGTCGATTTACGGAAA
+TTAATTAAAATAATTGATAAACAAAACAGAAACTATGTTCAAAAATCGAG
+ATCCCGTAAATCGACACAATCGCTACAGTAGTAATTTAAAAATTACTGTA
+GTTTTCGCTACGAGATATTTTGCGCGTCAAGTATGCTAAAAAATATGTAG
+TTGTGGGAGCCTTGTGAATTTTTAGAAGGTTTTTTGAAAAATAACTCGCC
+ACTATTAAAAAAAATATATATTTTGAGGCATTTTCAAAGGGTTAAAGTAA
+TTTTTTACTTTTAAAATCGTTTTTTTTTATAAAATAAATTTTAAGCGTTT
+TTAGTACAATTTTCGTAAGTTTTTCGTTTTTTTTTTGGTCATATTTTGTA
+GTTTTTTACACTATTTTCCAGAAATCGTCAGAAAAAGCACTTAGAAACGG
+GCTAGAAAAACGGGGTTTCGGCTTGCTGCGAAACTTTTTTTTTTGAAATT
+ACCGCGCAAAAATAAATTGTCATTCAAGTAATGTTGCAAAATGTATTAAA
+ATATAGGTTTTTAAAAATGTATTTTAATACAGTTGTGACGTAATTTTTCT
+ATTTCAATTTTTGCAAAATAAGAAAAAAAATGAATGTAAAAAAGTTAGAA
+AGTTTTTAAAACACATTTTATACAGGTCATTACGCTCTATTTTCTGCCAT
+TTAAAGCGAGAATGTTTTTTGACACTACATATATAATATTAGGTCTCCAA
+ATAAGATCCGGGTCAAAAATCATAACTTTGTTCGCTGTGTATCGATTTTT
+ATGAAATTGTGGGAATTTGTGTTATCAACCATGATCTTTCATTTGACAAT
+AGTCACAAAATTTTTTGGCCGTCCGAAGTGCCCGTACTCGGAGCCAATTT
+TTTCAGACATTTTTCAGATCTCGCTTCTTTTCAGGTTTCAACTGAGGTTT
+GTGTGCGGATATTGCTTAGTTTAGTACACAATGTAAGAAAACAAAAAAGT
+TTGGAAAAAAATCCGTCCAAAAAAAATTTTTTTGTCGCTCGTCAAAAAAT
+CTACAAAAAAAATTTTGTCGAAAATTCTTGAATTTTTATACAAAAATGAT
+GTAACCGTGTGCAAACTAATTTTAAACATACAAAACATTTGAGTATGAAA
+TTTGGATCTCGAGAAATACTCCAAAAACTCGAAAATAGTTCGAAAAAGCT
+GTGTTTTTTGTTATTTTTTTTAGTGTGACGCACCAAATTGAAATTTTTTG
+TATGTGTAAAAATAGTTTGCACATGGTTACATCATTTTTGTATAAAAAAT
+CGAGAATTTTCGAAAAAAAATTTTTTTGAAGATTTTTTGACAACCGACAA
+AAAAAATTTTGTTTGGACGGATTTTTTTCCAAACTTTTTTGTTTTCTTAC
+ATTGTGTACTAAACTAAGCACAATCCGCACACAAAGCTCAATTGAAAACT
+GAAAAGAAGCGAGATCTGAAAAATGACTGAAAAAACTGGCTCCGAGTTAG
+GGCACTTCGGACGGCCAAAAAATTTTGTGACTATTGTCAAATGAAAGATC
+ATGGTTGATAACATAAATTCCCAAAGTTTCATAAAAATCGATACACAGCG
+AACAAAGTTATGATTTTTGACCCGGATCCTATTTGGAGACCTAATATATA
+TATATATATAAAGATACCTACCGTAACCGCATTTGTAATATCATCAGTGT
+CATGAAAAACGTTATCCTCTGCAATTGTGTTCGACGATGACATACTATCT
+CCAGTCTCTGACGAATCATTTCTCGGGTCTTCCATCATTGCCGATTCGAT
+TGCCTGTCGTCGACTGTTCTGTGAGACTTCTGTCGCTTTTCGGAGAGCTT
+CTTCACGGGAGAATATGTCGATATGGGCGAGATGGAGGATTAATGCTCGC
+GTTACACTGTTCACAATCTGAAGATTTCGTTTTATTTTTTTGATTTTGGC
+TGGAATTTCATAAAGCTATGCTTTTGTTGAAATTTTAGTTTAAAAAAATA
+AGGTTTTTGAACTGAAAATTGGGATAAGAATTAGAAAAAAATTTGTTTTT
+TCTCTAAAACTGCTGCATTTTATTCAATTTTGTAAGATTTTCTGTACAAA
+ACATAATAATTTTTGAATTTTTTTTCCAAATTTTTTGAAATTTCAGCAAG
+AACTGGACAAAAAGCACTACTTTTACTAAAATTGGCAGCATTTAGGAATT
+TCTGAAAAAAACAATTAATTTTCATTATTATTGTCATATTACAGGAACAC
+ACTATTCTGAGAATGCGTATTACACAACATATTTGACGCGCAAAATATCT
+CGTAGCGAAAATTACAGTAATTCTTTAAAAATGACTACTGTAGCGATTGT
+GTCGATTTGCGGGCACGATTTTTTGAAATGAATTTTAATCATATTTTGAG
+CAAAAAATGGGTCAAAAATCAAGCCCGTAAATCGACACAATCGCTACAGT
+AGTAATTTAAAGAATTACTGTAGTTTTCGCTACGAGATATTTTGCGCGTC
+AAATATGTTGTGTAATACGCATTCTCAGAATTTTGTGACTTTTCAAAAAA
+AAAAATCGTGATCAAAAAAAATTTTTAATTGTTTTTTAAGATGAAATTAC
+GATTTTTTTCGTTCTCTATAAATTTTGATCAAATTTATTTCAAAAAAAAA
+AAAAATTCTTTCTATATTTTTTTTTTCGAGTTTTTTTTTCTATCTTCTGT
+ACAAAACACAGCAATTTAAAAAAAAGGCAAAATTTTAAGATTTTTCTAAA
+TCTAGATTTCTAATTTTCCTCGGGGTTCTGGCCATCATCCTCATAAACAG
+AAATGGAAGAGTTTTTGCCGAACTAGGCCATTTTGAAACTCTTCCATTTC
+AATTTATGAGGAAGGCCAGAGCCTCGTGGAAAATTAGAAATTAGATTTCG
+AAAAATCTTAAAAGTTTGCCAATTTCTTATTAGATTGATGTGTTTTGTAC
+AGGAAATTGAGAAAAAAATCGGCAATTTTATACAATTTAATTTTAAAAAA
+TATAGTTAAAAATAGAAAAATTCAATGAAACTGGAAAAAAATGTTTACTT
+TGAAAAGTTAAAAAAAATGAAAAAAAAACTCAAAAATTGAATAAAATGCG
+GCAATTTTTGAAAAAAAAGCTTTTTTCCATAGTTTCTGTCAATTTTCGGC
+TAAGATTAATTTTTTTTCATCAAAATTTCGATTTTCATACTCTCTTACCG
+AAGCCCATTGCTCAGCCATCGGTATCCAAACACCCTTCTTCATGACGTCA
+TGCACCTCATCCCACACCTCATCGTCAATTTCGATGCGTCTGACAGCCTT
+AATCACGACGACATTCGAGATGAGTGTCGACGTAAAAGCAGCCGACACAT
+TCTGGGAAAACGCGTCCGATTGGCGACAGATTTTCGAGGCGCATGTGCAG
+AGTCCCGCCATTAATTCTGACCAGAATTTTTGGGGAAGCGGTTTTGGGAG
+TTGAATTCGATGGGAAACCAGCTGCTTGCACGATGTTAGAATCGCAAATG
+CTATGGAGATTGCCGAGGAGTGACTGGAAAAATATTTTTTTTTAATTTTT
+AAAGGGATTTTGGGAAATCGAAAAATTTAAAAACTCGGATTTATGAAGTT
+TTTGGCAAACCGGCAACTTCTGGTTTTTGGAATTTCGCCACTTTTTAACA
+ACCGGCAATTTGGCGATTTGCAAATTTTTGGAAAACCGGCAATTTATGGT
+TTTTTTTTCGGAATTTTGCTAATATTTTTAAAACCGGCAATTTGCCGATT
+TGCAAATTTTTGGAAAACCGGCAATTTGTGGTTTTTGGAACTTGGCCACT
+TTTTATAAACCTACAATTTGCCGATTTGCAAATTTTTGGAAAACCGGCAA
+TTTCTGGTTTTTTTTTGGAATTTTTCTAAAATTTTAATAAACCGGCAATT
+TGCCGATTTGCAAATTTTTGGCAAACCGGCAATTTGTGGTTTTTTTGGAA
+TTTTTCTAAAATTTTAATAAACCGGCAATTTGGCGATTTGCAAATTTTTG
+GAAAACCGGCAATTTTTGATTTTTGGAATTTTGCTAAAATTTTTAAAAAC
+CGGCAATTTGCAAATTTTTGGAAAACCGGCAATTTGTGGTTTTTGGAATT
+TTGCCACTTTTTATAAACCGACAATTTGCCGATTTTCAAATTTTTCGGCA
+AATTGCAGGTTAATAAAAAGTGGCAAAATTCCAAAAAAAAACCAGAAATT
+GCCGGTTTTCCAAAAATTTGAATATCGGCAAATTGTAGGTTTATAAAAAG
+TGGCAAAATTCCAAAAAACCACAAAATGCCGGTTTTCCAACTCTTTCAAC
+GAGAGTATCCAATTTTTTAAATAGAAAAATTGCCGTATTCCCTACCGTTC
+TCCACACATTTGCCGATTTTCAAATTTTTGGAAAACCGGCAATTTTTGAT
+TTTTGGAAGTTTGTAAAAATTTTTTAAAGCGGCAATTAGTGGTTTTTGGA
+TTTCTGTCACTTTTTATAAACTTACAACTTGCCGATTTCAAATTTTTGGA
+AAACCGGCAATTTGTGGTTTTCAAGTTTTCTGCTAATTGGCAAACTGGCA
+AAATGCCTTATTTTGGAAGTTTAGGTAAATTCTCAGAACACCGGAATTTT
+GACATTTTTCAAAATTCCAAAAACCACAAATTGCCGGTTCGCCAAAAATT
+TGCAAATCGGCAAATTGCCGGTTTTTAAAAATTTTTGCAAAATTCCAAAA
+AACCACAAATTGGCGGTTTGCCAAATTTGCGAAATTCCTAAAACTGGAAA
+TTGACGGTTTTCAAAAAAAAAAAAAGAAGGGAAATCGGCAAATTACAGAC
+TTACAAAAAGTGGCAAAGTTGCAAAAGCCAGAAATTGCCGGTGTGCCAAA
+TTTGCGAACATTTGAAAATACCACAAATCAAATTGCCGGTTTGCCGAAAA
+TGTGCAAATCGGCAAATTGCCGGTTTTTGAAAATTTTTGCAAAACTCCCA
+AATTTACAGAAAAAATTCCAAAAATCAAAAATCCGAATTATTCCAGAATT
+TTTTCTTCGGAAAAATTAAAAATTGTTCAATTTTCCAACATTTTCAACAA
+GCGTATTATCGAAAAAATACAATCGCACAAATTTCTCGTAATTTATTTTT
+GATCTACCTTGTTGACTAGGCTCCGCCCCTAATCTTGTTGCTGTTGTTAT
+TGTTGTTGTGGCTGTCTAGTTGAAGGAAGGGGCGGAGCCTATTCAACGAG
+GTAGATCAAAAATAAATTATGAGAAATTTGTGCGATTGTATTTTTTTTCG
+ATAAAATCCAATTTTTTAATGGAAAATTGCCAATTCCCTACCGTTCTCCA
+CATTGAGCCAAATACGGACTGTGAAAGAAGCCCAACAAGATATTCGAGAG
+CAACAGCGAGCATCGTTCAATCGATACTTCTCCAGACGCTACGAATGGTG
+GAATTTCGTACTGCAAAAGCCATGCGGAGAGCACATTTACCACTTTATGA
+GTGACATTTGAGCATGCCAATGGGAGTTTCATTGCTTCACGCATTAGTGT
+TAATGCTACGTTTGTTGCCTGGAAAAGGACAAAAAAAACTATTTTTTTAA
+ATGTAAGTAATTAATTTATTTTTTGAAATCTCTTTAAATGTGGTGTAGTC
+GAATATTTTTTCAATTGCTTAATTACCCTCAAAATTGTCTGAAAACACCG
+AATTTCATAATGAACTTCTTGAAAACTTCTCAGAAAAAAGTTATGACGCC
+TCAAAAAATGGCCTAAAATTGGTTAAAATTTGAAATTTGACCTACTTGCC
+AAGCGGCTGGAAACTAGCTTTTTTTTGAAATCACTGTCAAATTTTGAGTA
+TTCAATTTAATTATCTTGCGTTTTCAACTCGATTCAGGTATTTTAAAATC
+GATAAACGAAGAGATTTTTAAAAATTATTTACCAAATCTCTTCTTCCATC
+GATTTAAAAATACATAAATTTAGTTGAAAACGCAAAATAATTAAATTGAA
+TACCCAAAACTTGACTGTGATTTCAAAAAAAAGTTAGTTTCCAGCCGCTT
+GACAAGTCGGTCAAATTTCAAATTTTAACTAATTTTAGGCCATTTTTTAA
+GCCGTCATAACTTTTTTTTTTTGAGAAGTTTTTCAGGAAGTTTCATTATG
+AAATTCGGGTGTTTTCAGATAATTTTTAGTATAATAAAGCAATAAAAAAA
+ATTCGACTACACCAACTTCAAAAATGTAAGCAATTTTATTTTGAAGGCGG
+TTTTCTTTTACTTTTCTAAAAAAAAAATTTATTCAATTTTACGATTTTTT
+GCGTAAAAAAACACGGTCAAATTTTTGTTAAATTCGAAAAGGCGTGTCCA
+TTACGGTTTGATCTACAAAGAATGCGTGAATTTTTAGCCCAAAAAGTGTG
+ACGTCAGCACGAAAATTCTGCGTCTCTTCTCCCGCATTTTTTGTAGACCT
+ACGTAGATCAAGCCGAAATGGGAGAGCCTGACACCACGCGCGTGTGCGCC
+TTTAAAGTGAGTACTGTAATTTCAAAAATTCCACAACATCGAGAGTTTGA
+AACTACAGTACTACTATTTAAAGGCGCACACACTTTTTCGAATTTAACAA
+TAAATTGTCGTGTTGAGACCGTATTTAGGGCTCAAAAAAAAAATAATTAT
+CTCGTTAGAATATTCGGGAAAGTTGCAGTTTCACTGAAAATTTGAATTTC
+CCGCCAAAACGAATTTTCTCCGAAAAATTTGAATTTCCGCCAAAAAATTT
+TTTTAAATCAGAAATTTGAATTTCCCGCCAAAATCGTATTTCTCAGAAAA
+TTTGAATTTTCGCCAAAAATAAAAAAAAAAATTTTGGCGCGAAATTCAAA
+TTTTCTGAAAAAAAAATATTTCGGCGGGAAATTCAAATTTTCTGAGAAAA
+TATTTTTTGGCGCAATTTTTCATAGAAATTTAGTTCTTTTGATGTGTAAA
+TTTCCAAAAATTTCAACAAAAAATCGCATTTTTCTTATTTTTTCCCCAAA
+ATTTTCAAATTTTCTCCTCCAAAACCACGGAACTTTATGCGACGAAAAAA
+GCGCATTTCGATACAAAATCAACGATGCATGTGTAGTTTGTAGTGTTGGT
+TGTCCTCCAGCCGTTGTGTGAGTTGTTGCCGATGCAATATTATTAATCCA
+TCGAATTAGCCAATATCTTGCAATTACCACCGGATCAGCTGTATCCAATG
+GTTCACCATTCTCATCGGCTCCTTCCCAGCCACCGAATACATCGACTCCG
+TTCGTTTCCAGATCGGTGAAGCATTCGCCCATGTATAGCTTTATTACTCT
+GAAAATTGAAGAGTTTTGTACTCCTCTCGGACAATTGGAGGTGATTTTTT
+TTTTCGAATTCTTTAAAACAAAAATTTCCCGAAATTGAGCTTTTAAAATT
+TTAAAATTTCAAAATTTCAAAATCAAAAAAAAAAAAAAAAACTTTTGTAC
+AAAATTTAAAGTGGAGAATTTTTGTATTTTAGACAAATTTTTTAAACATT
+TCTAGCAGAGTTGAAAATTTCAGGCAAATCGGCAATTCGCCGAAATTGAA
+AATTTCTCATAAATCGGAAATTGCCGAAAATGAAAAATTCCGGCAAGTCG
+GCATATTGCCGGAATTGAAAATTCCTTACAAATCGGCAATTTGCCGGAAT
+TGAAAATATCCGGCAAATCGGCAATTTGCCGGAGTTGAAAATTTCCGCCA
+AATCGGGAATTTGCCGAAATTGAAAATTTCGTATAAATCGCCGATTTGCC
+GGAGTTGAAAAATTCTGGCAAATTTGAAAATCGGCAATTTGCCAAAGTTG
+AAAAATTCCCGGCAAATCGCCAATTTGCAGATTTTTCGACCGAAATTTGC
+CTACCGGCAATTCCTGCCGACCCCTTTTTTCCGAGAAGAATTAACTTTCC
+ATTTCTAAAAAATCTGTAATTTGCCGGAGTTGAAAATTTCCGGCAAATGG
+GCATTATGCCGAAAATGAAACATTCCGGTAAATCGGCAAATTGCCGAAAA
+TGAAAAATTCCGGCAAATCGGCAATTTGCCGAAGTTGATAATTTCCGCCA
+AATCGGGAATTTGCCGAAATTGAAAATTTCGTATAAATCGCCGATTTGCC
+GGAGTTGAAAAATTCTGGCAAATTTGCAAATCGGCAATTTGCCAAAGTTG
+AAAAATTCCCGGCAAATCGCCAATTTTTTGCCTGTTGTGCATATTATTTT
+CACGACTAAAAATCGTAATAAATTAAATTAAATTAAATTTGCCGATTTTT
+CGACCGAAATTTGCCTACCGGCAATTCCTGCCGACTCCTTTTTGCCGAGA
+AGAATTAAAATTTCCATTTCTAAAAAATCTGTAATTTGCCGGAGTTGAAA
+ATTTCTGGCAAATTTGCAAATCGGTACTTTGCCGGAGTTGAAAAATTCTG
+GAAACCGGCAACCCGGCAAACCGCCAATTTGCCGATTTTTCGACCGAAAT
+TTTTTTTTCCTGTCGACCCCTTTTTCCGAGAACAGTTAAATTTCCAAAAT
+TCTCTAAAAACCACAAACTTCTCAATAATAAAATTCGCACACTCCTGTCG
+CTTCCCCTCATCATTCCACTCAATCCGCACAGTTTCTCGAGTACAGTACT
+CCAAAAACTTGTCCAAATAAACTTGGAGCATTTGAGCCCGTTCTTTCGAA
+GTCTGCGACGCCGACGCTGTCGACTTAATCGGCCCATTCCTCAGTCGTTC
+ACACCAATCACCGGCTCCCGACGATTGACAGTACTCGTTGAGCACATCTT
+CCGCATTTTCACCACTGGTAAGCGGGAAGAATGGTAGAAGACACTGAAAG
+ACACGATCCAGGTCTGGTGTCGCTTTTCCGTACACTCCGAGACATTGATA
+GAACACTAGGAACAAGCGAATCGCAATTTTTCGCACTGCCATCAAATTTT
+TCGGGTAGACTGCTTTTTTGAGAAGCGATTCGATTGCATGACGTTGCCAG
+CCTGAGAGAAATTGGGAAAATTTTTAATTTTTATTTAAAGGTGGGGTAGC
+GCTAGTGGGGAAATTGCTTTAAAACATGCCTATGGTACCACAATGACCGA
+ATATCATGATATAACAATTCAAAAAAATTTTCTAAATTTTATATGATTTT
+TTGAAAATTGAAAAAATCTCAGTTTTTGTCTAATTCCAATTTGAATTACC
+GCCAATTGAATTTGTTCTATGGAGCGCGCTTGCACGTTTTTAAATTTATC
+TATTTTATTTTTTGTTATTTTTTGTTATTTTTCCACCAATTTTTAATGTT
+TTCGGTGTATTTTTGCTCGAATTTTAGAGAAAAAGTCAAAATAAATGCAA
+ATTTTCGATTAAAAAGCACGCTTACAGTCGTAAATCAGTGAAATTAATTA
+ATTCAGGTTTGAAATCGTTTAAAATCGTTACTTTGTCATTTTTACGCCTG
+TAAGCGTGCTTTTTAATTGAAAATTTGCATTTATCTTGACTTTTTCTCTA
+AAATTCGAGCAAAAATACACCGAAAACATTAAAACTCGGTGGAAAAAACA
+ACAAAAAATAAAATAAAATAAATTAAAAAACGTGCAAGCGCGCTCCATCG
+AACAAATTCAGTTGGCGGTAATTCCAATAGAAATTAGGGGGGAAAACTGA
+GATTTTTTCAATTTTCAAAAAATCATATAAAATCAGGAAAATTTTTTTGG
+ATTTTTTATCATGATATTGGGTCATTGTGGTACCATAGGCGTGTTTTAAA
+GCAATTTCCCCACTGGCGCTACTCCACCTTTAATTTCTGACGGTTTTTTT
+TCGGTTTTCCTTGAAAAATCCTCTAAAAATCGATAATTTGTAAAAATTGC
+GTTGTTTTTCCGGGATTTTTTTCGGTTTTCCCACGGGGTTCTGGCCTTCC
+TCACTGAATTTTTCGCGCTCCATTGACAATCGCCCGTGTACTCCACACGG
+ACAAATCACATTTAGTTTTACAACTAAAATCGAGCCGAGACGCGGCAGCC
+AACGCGCCGTAAATCTACCCCAGATATGGCCTGGCCTAGTTCGGCGAAAA
+CTCTTCCATTTCAATGTATGAGGGAAGCCAGAAATCCGTGTTTTCCTCAA
+AAAAATCCTCTAAAAATCGATAGTTTGTAAAAATTGCGTTGTTTCTTCGG
+TTTTTTTTGCAATTTGAGGGTTTTTTGTCGATTTAACACGGATTTTTGGC
+TTCCCTCATATATTGAAATGGAAGAGTTTCTGCCGAACTAGGCCAGGCCA
+TAACTGGGGTAGATTTACGGCGCGTTGCGTGTCGCGTCGCGGCTCGATTT
+TAGTTGTAAAACTAAATGGACTTTGTCCGTGTGGAGTACACGGGCGATTG
+TCAATGGAGCGCGAAAAATGCAATGAGGAAGGCCAGAAGCCCGTGCGGAA
+AGACGGGGAATCTCCGAAAAACGGGGAAAATCTACAAAAAAATGAGTTTA
+AAAAAGACTTCCTCAAAAAAATTCAAAAATTGTGGTTTTTTTTTTAATTT
+TTTGTATTTTGATAAATTTTTTGCGACATCAAAAAATGGAAGAACTTTTT
+TTTTTCGATTTTTGAATTTTTTGTTGGTGAAAAAGAAGAAAATTTCGAAA
+ATTCGTTAGGGAATGGATAAATTTTAATCAAAAATCGATTTTTTAAAATT
+ATTTTTTGCAGTTTTGCATAAAAAATCCAGATTTTTTCGCATTTCGCGCG
+TAATTTTCATTTTTGTCGTTTTTTTTTTCTGAATTTTCCGAAATTTCTGG
+AAATTTTTTCTTTTCTTGTTCTGAAGCTTATGCCTAAGCCTAAGCCTAAG
+CCTGAGCCTAAACTCCAAAAACGCACCACTTCCAACAAGCTCCGGAGCCA
+AACAGAGCACCTGCTCCAGTGTCCAAAGCCCGGATTCAGCCTCAATTGCA
+CTATCGATTTGACTGCTGACATCGTTGACGAGCAGAAGCTCGTCAACGAG
+ATGAAACGTCTCGAAACTGTGCTCATCGAGCAGTTGACGCTTTTCCTGAA
+GAAATGTTGTGGTCGAATTAATGCGAAATATGGGAAAATTCGGGTTAAAA
+TCGATGAAAAATCGTGGAAAAACGAACATTTGTGGTTAATGTGTCGAGCA
+GAATCTTCAAATGTTTCACACGGCTCACACAATCCCTGTTCAAGTCGGTG
+AATCTTGAAATGCTCGCCTGCACATCTGACGATTTGCCCTTTCGGGCAAA
+CATTTTCCTGTGATTTTAGGCGATTTTCTGCAAATTTTCGCTGTTCAAAC
+GTTTAAAATCGACGGAAAATGCGTATATTTTACTAAATATGCGAGAAATA
+GTGATTTAATTCGAAAAAATCAATATAAAAATGGAAAAAAACTACAGTAG
+TAATTTAAAGGCGCATACCTCGAAAGTTAAAATCGTGCCAGGACCCGCCG
+CAATTTAGAATCGATTTTTAGATGAAAACTTTTTTTTTCTTACTAAAAAT
+TAAAATTTTTCACTGAAAATTTCGGTTAAACTCTGACTTTTAACACGAAT
+CTTATCAAAACTATGACAATTTCTAGTGAAAATCGCCAATTTTGTGTGTA
+AAATCAATTTTTTCAGTGAAAAATGTTTTTTTTTGAGTTAAAACTAAATT
+TCGAGCTTGAAACTAGAAAATGTCAAGTAAAAAATTCATTTTTAAGCGAA
+AAATTAACGTTTTTTTCCAAATTTTCGCCTATAATTCACACAAAAAATAC
+TGAGTCAGCAAACAATGTGGGAGCATCCCGAAAATGGTGCAGAATGGTAG
+AGCAAAAACGAAAAATCGATGAATTATTGTGGAGAGAGAGGAAATTTTAT
+TCAATTTTTGAGGAATGGAGGTTAAAAAAAAGAGTAGAAACATTGAAAAG
+TGGCAAAGAAATCCAGCTTGAAACCGGAAAAACTCCCAGAAAACGAAGCA
+AATAAGAAAATCCCACAAAAAATCCGAATTTAATTGCAGTTTTCGACCGA
+AATTCAGCCAACCAGTGAGTGGTTCAATTATTAAAAAGCACATATATACA
+TATAACTTTATTCAAAGGACATAATCCATATAAAGTCTGTCAAAACGGAA
+AAGGTTCTTTCCAAACACACAATTGGCCCCCTCTGTCCAAAAGAGAGAGC
+ATGGGAATCGGAGAGGGCGGTGAGAGAGACGCAGACATCGAGATGACACT
+TTTTGACAGCAACACTGTGTGTGTGTGTGTGTGTGTGTGAGTCTCTGTGA
+TTGAGTGAAAGCACTTTTGGGAATATATACTGGTAGAAATTTAATTTAAA
+ATGATAAAAAATTTCTTGGGATTTTTTTTTTTGAGTACTGTAGCCACAAA
+AGTACGTAATTTTCTTGAAAATGCGCCCATGGGGTCCCAATGACGTAATA
+TCATGATAAAAAATTTTTGAAAATTGGAAAAATCTCAGTTTCCCCTCCCC
+CCCCCCCCTAATTCCAATTTGAATTTCCGCCAATTGAATTCGTTCGGCGG
+AGCGCGCTTGCATTATTTTTATTAATTTATTTAATTTTCTCTGTTGTTAT
+TTCACTGATTTTCTTCATTTTTTGGGGATTTTTAATTGGGAAAAGAGAGA
+AAAATGCAAGATAAATGCAAATTGTTCATTAAAAAATCACTGAAAATGGG
+TAAAACTGTGAAATATGCTAATTTCAGGCTTGGTGTCGTCGGAACTCATA
+ATTTCGCAGTTTTACCCATTGTCTATGATTTTTTAATGAACATTCTGCAT
+TTATCTTTTTTTTTTAAATTCAATTTCTATTAAAAATCCCCAAAAAATGA
+AGAAAATCAGTGAAATAATTAGAAAAAATAAAATAAATTTATAAAAATAA
+TGCAAGTGCGCTCCACCGAACGAATCCAATTGGCGGGAGTTCAAATAGGA
+ATTAGAGGGAAAACTGAGATTTTTTTCAATTTTCAAAACAAAAAATCATA
+AAAAATAAGCATTTTAGCTTAAAAACTCGAAAAATCATACAAAAATTAAT
+TTCAAGTTGTCCACGAGTAGTACGCGACGCCTGGTTGCAAAAATGGCGTA
+GATTTCGATTATTAAAAGCTTAAAAATCATTTTTTTTTACCAATTTCCAA
+TTAAATATCCTAATTTTAATCTCAATTTTCTTGAAAGACGTGCAAATATA
+GATACATCTAACATAAAAATTCTTCGCTGCGAGACCCAGGACCCCATAAA
+TCGCCTGCGCCTTTAAATTTATATTTATTTTCTCTCTCAAACAGCGATGA
+AAATCACGTTTTTGAACCAAATTTTCCAAAAAATAAGACAAATTTCTATT
+TTAAAAACCACTTTATTCGGTCATTGGTCGCTAAATAGCAAATTTTGAGG
+CAAAAAAAAAACGAACAGACAACGGAAAATCGAGTGAAAACAAGTGAGAA
+CACAGCAAAACTAGTCCTAATTAATTAAAGGCGCATCACGTGGAAAAGAA
+AACTGTTGTGGAAGAATAAAAAATGGAACATGAGGGGAAATATTACAAAA
+ATAGTAAAAGATGCATCAAGATTAAGATTATTTTTCGAAAATCGAGTCCT
+CCGCCCAGGAATTCATCATAATTTTCGACTTTTTTTCGGAGATTGCTGCA
+CATTGTCGGCTGCTCCGGTGGTTTTTGGAAGGTTTTGAGAGCTGAAAGAT
+TTGAATTTTTTGGAATTTCGAGAAATTTCTTTTTTTTTACCCGAAGCGCT
+TTGAATCTGGCGAGCTGCATTTCCAGCTTGCATTGTGCGTTCAGTGACTT
+TGATTCCTTGAAGTTTTCTGAAAAAAAAACACGAGTTTTGACTTGAATTT
+TCTGAATTTTTAACACGGATTTCTGGTTTCCCTCAAAGAATTGAAATGGA
+AGAGTTTTTGCCGAACTAGGCCAGGCCATATCTGGGGTAGATTTACGGCG
+CGTTGCGTGTCGCGTCGCGGCTCGATTTTAGTTGTAAAACTAAATGTGAT
+TTGTCCGTGTGGAGTACACGACTTTCCCACGCGTTGTCCGGCAGGCGATT
+GTCAATGGAGCGCGAAAAATTCAATGAGGAAGGCCAGAACTCCGTGATTT
+TTCTTTTACTCGGCGTAGATTTCGCAGTTTCAGACTGTTTTTCAGGTCTA
+ATCAGCGGAATTTTCGTTGATCCCGCCAATCTCGGTGATTTTCTGAGCCT
+TTTTCGCTCAGGTTCTGGGATTTCAGCTTTTAGAGCAATCTTTGAAATTT
+CGACAAGTTTCTTGAAGTCCAACGCAATTTTTTCAGTAGAATTCGCAGTT
+TCCGGCAATTTTTCTGAGCAAATCTTCGAAATTTCGACAAGTTTTCTGAT
+TTTCGGCGTAGATTTCGCAAATTCTGACGGTTTTTCTGCAAATCCCGGTG
+ATTTTCGGCTCGGGGAGCTCCCAGCTGCTCTATTGTTCAGCATTGTCTGC
+TCAGTAGCGGGGGCGTCTTGATTTTCAGTAGAATTCGCAGTTTTCGGCAA
+TTTTTCTGAGCAAATCTTCGAAATTTTGACAAGTTTTCTGATTTTCGGCG
+TAGATTTCGCAATTTCTGACGGTTTTTCTGCAAATCTCGGTGATTTTGGG
+CTCGGGGAGCTTCCAGCTGCTCTATTGTTCAGAATTGTCTGCTCAGTAGC
+GGGGGCGTCTTGATTTTCAGTAGAATTCGCAGTTTCCGGCAATTTTTCTG
+AGCTAATCTTTGGAATTTCGACAGGTTTTCTGACTTTTGGCGTAGATTTT
+GCAGTTTCTGGTGATTTTCGGCACGATGAGCTCCCAGCTTCTTCATTATT
+CAGCCTTTTCAGCTGGGCTTCTTGAGAGCCTGTAATCACGTCGCCGTCGT
+CATCCTCTGAATCATCATCCGACCAAATTTCGATTATTTCCTGAAAAAAT
+CGATTTTTTTTGCTTTTTTTTGCTCTTTTCTCATTGTCAGCTTTTCCCAC
+TTTCCAGCAATTTCTCCACGGCGTCGGAACGTATCCTGGTCGCCGATCGA
+ACTGGATAACTGGCCGGCTGGCGATAAATCGGCGAAGATCTGCTACTATC
+TCGTCTGAAAACGTTTTTCTGCTAAAACCTGCTAAAAATCTGGCTAAAAT
+CACCTGATAACATTACAATATCATCATTTCCGGGCATTTTTGACGAAAAA
+AAAGCGGAAAATATTTAGAATTTCGAAAATGAAGAGAAGCGTTACGGTAC
+TAAAGGCACATGGCGTAAAATATTCCGCAGGACTCGCCGCGATTTATGAT
+TTTCACTATTTTTTTTGGGCAAAAGTTGACATTTTTCAGAATAAAATTCA
+AAATTGTGTTGATAAATTGTTTATTTGATTTTTTTTTCAAATTTAAATAA
+ACTGTAAATTTTAAATTTTCCCCCAAATATTCGCAAATTCCCTTCAAACC
+AAGTTTTAATAGCACAGTAATCCCCGAGCAATCGCGCTCCACCGGACTAA
+CCTACACACCGCGAATTTTGAATTACATCCCTCATAATTAATTGTTTTTG
+CCATTTTTTCGCTATTTCCAGTGGATTTTAATGAGTAAAAGCCTACAAAC
+CGACGAAAATGGCGGTGTCAGTGAAAGTCCATCAAATTGCACATATTGCT
+ACACGCTGGAATGCTCTCTACGCATCGAATCCACCTCATCAATCAAGAAA
+AAGACTCCAATCTCCTCGAAAAGCGCTATAATGACTGTCGGCAGAAATGC
+GCAGAGGTTTTAGTCGAATAAATGCCTGTTTTAAGAGCAAGAAATTCCAG
+AAAAATTCACCTTCAAATCGAGCTAAAGACCACCGCTACCGGACAGCCCG
+CTGTAGTGTGCTATGACGTCACAGATGCAGTTGTACACTTGCAAAGCGTT
+GCAAATGGGAAGTGTACTGTAGAAATTCCTTCGCTGTAAGACCTAAAAGA
+CCAGAAAAATGGAAAATATCTGAAAACCCCAATTTCAGCTCGTTAATGTT
+CCAAATGTTCAATTGCGCGCCGCGAAAGCTCAACGTCTTCATGAAATCTC
+TCCAAGCAAAGTTGGATATTATGAAAATGGAGAAAAGCCCAATTTCAGCA
+GTGTAAAATCGATAAATTATCGAAAAATCAATAAAAATCCCTTCAGACCC
+CGGCAATTCTCACGTCCGCCGGCAGTTTTCAGCGTTCTGAGCCCGCTGAC
+GATCAGCGAAATGCGAAAAGTGAAGAAGCTACGCGAACCGTCGGCGCTGG
+CGAGACCTTCGAAAGAGGCGACCACACCGAAGCGGCGGTAATTTGAAATT
+TTCACATTAAAAAAAAATCGCGAATTTCAGCACTTCCTCAATGAATTTGC
+TCGCCGGCGGCTTGGAAAATCGAATTATGAATCGATCGATTGGGCTGAAA
+AGGACGACCAGTTTTGCTAGAGATGATCGTGAAAAAGCCGAGGTTCTGCA
+GCTAAAAATCCGTCAAAAATCGATAAAATTTCGTTTTTTTTCCGTGAAAT
+TCCAGGTTTTTTAGTCCAAAAGCACGGATTTCTGGCTTCCCTCATAAATT
+GTAATGGAAGAGTTTTTGCCGAACTAGGCCAGGCCATATCTGGGGTAGAT
+TTACCGCGCGTTGCGGCTCGATTTTAGTTGTAAAACTAAATGTATTTGTC
+CGTGTGAAGTACACCACTTTCCCATTGCCCGGCGGGTGATTGTCAATGGA
+GCGCGAAAAATGCAATTAGGAAGCCCAGAAACCCGTGAAAAAGTGTCACG
+CGGTTTTCAAAGTAGAGGTGCAAGCGCGCTCCACCGCTCCACGGTGCTTG
+GCGGCAAAACCAGAATTTTCGCTGATTTCAAGCATTTTCCGTCGTTTTTC
+ATGATTTTTCATGTCGAAATAGTGTTTAAAAATGTCTTTAATGCTGAAAA
+GTGAATATTTCAAAAATTTTGACATGAAAAACTGAAAAAATTATCGGAAA
+AGTGTATTTTTTGAGTTTTTACTTATTTTTCGGTTTTTAAAAAAATTATT
+TCTACATAAAAATTGATGAAAACAGCATATGAAGTGCAAAAAATAAAGAA
+GACTTACATAAATTTTGACAAAAAATCACGAAAAACAATAAAAAAAGTCG
+AAAAATGATTGGAAACGGAGAAATTTTCCCTTTTTATGTAGAAATTTTGA
+ATTTTTTCAAAATTTTCTCAATTTTGAAACACAAAACATGAAAAATGATT
+GAAAATATTTGAATTTTTAGTTTTCGCGCCAATACCTAACGAGACCCATC
+GGTGTGACCATGGAGCGCGCTTGCATCTCGATTTTAAAATTCGTATGAAT
+TTTTCGCGCTCCATTGACAATCGCCTGCCGGACAACGCGTGGGAAAGTGT
+CGTGTACTCCACCCGGACAAATCACATTTAGTTTTACAACTAAAATCGAG
+CCGCGACGCGACACGCAACGCGCCGTAAGTCTACTGAGCCAAAATGGCCT
+AGTTCGGCAAAAACTCTTCCATTTCAATTCATGAGGGAAGCCAGAAATCC
+GTGTTTTAACCTAGAAAATCAAGAATTTTTTTGGGAAAAAATGCCAAAAA
+TCCCAGATTTTCCCTAATTTTCAGCTAATTTTTCCCCGAAACAGACAATT
+TTCAGACCCTTGTCTCCCTGAAATCATTCAAAGATGCTCCTGCAATTTCC
+GAACGGATTCAGCTGTCAGATGAGCAAAAATCGGTTGTCCGATGTGTGAT
+AAATGTAATTTTTCGTTCGAAAAAAAAAATTATCGAAAATTTGCAGTCTC
+GAACGAGTGTCTTCTTCACGGGATCCGCTGGAACCGGAAAATCTGTGATT
+CTTCGGAGAATCATTGAAATGTTGCCCGCCGGGAACACCTATATCACCGC
+AGCGACAGGTAGAGGATCACTTTGAAATATTTGCAAAAAATCGTGTCAAG
+ACCTCCCCCAAAAAATTTTCATGTACCTTTAAAAAATAGAACCGACTTTT
+TTTAATTAAAAAATCATTAAAAATTAGAGGAAAATTTGGGAAAAAAAATC
+ATTAAAAATTCTTTAAATAATAATTGTTTATTTGTCACAAGAAATAGCTA
+CACCGGAAGATAAAGAAAAAAAGTAAATAAAAAAGATGTGTGGACAAATA
+AGTAAAATGACCAATTGGACCAGCTATAGCCCGGGAGGTTAAGTTGGGGG
+GAAGAGGGTGTCAAATGGGATAGAGTCTAGGCGCGACGCAAATGCATTTG
+GAGTTAACAGTTTAGGGAAACGTTTTGCTATTCGATTCCACAACGACAAG
+TTAACATGTAGAAAACATTTAGACGGAACACCACAGACAACAAGTAGATA
+GGGGTGACGAGTAGAGCGTGAAGCTCGAACGAACGATGATAAGGACGGGA
+AGTGATACTCGCTTGAAATAATTTTATGGAAGGTTCGGAGGATTTGAAGA
+ACCCGTCTATGGTGGGTAGACAATAAATTAAATTGGGAAAGCCTACTACT
+GTATGACGAGTAAGATAAATTGCACCTTTGAAAGACACACTTTGAGAAAA
+ACCGGAGGGGAGATTCTAGTTTTTTGGCAAGTTCGGTGGAGTTGGGCGGG
+AAGAGCTCGCAGCCATATTCGAGTACGGGGCGGATGTAAACATTGAACAG
+TTTAAAATAGAATTCGGGACTTTTAGAGCGGAATGAACGAAGGATTTGGC
+GACACTTAAGGAGGGCACTATTAGAAGTCTGATTAATATGATTAACAAAT
+GATAATTTGGTATCGACAATGATTCCAAGATCTCTGATAGAATCACGCGG
+TTTAATTTCAACACTATTTACAAAGTATTTATGACGGGGGTTCTTTTTTC
+CAAAATGTAATACGGCAGTTTTGTGCTCAGCAAGATTTAGACGCCATTTT
+TTACACCAATCAGCGACAATATTGATGCTTGTTTGGATAGAGGTGGGGTC
+CGATCCGAGTAATTTTAGATCGTCGGCAAAGGCTGTAACATGGACATCAG
+GGGGGAACAAATCTAATAAGCCATTAATATACAAAAGAAAGAGGAATGGT
+AAAATTGTGGAAAAAACCGTAAAAAATCAACAAATTTCGAAAAAAAATCG
+TAAAAAATTGAGACATTTGAAAAAAAAAATCTAGCAAAATTTGAAAAAAA
+AATCGTTTAAAATTCAGCAAATTTATTTTAAAAAATCATTAAAAATTCAG
+CAAATTTGGAAAAAAAAACAAATAAATCTGTAAAATTAAAAAAAAAACCA
+GTAGAATTTGAAAAAAAATTGTTTAAAAAATTCAGCAAATTTCTAAAAAA
+AAATCATAATTAATTGATAAAAATTTTTTAAAAACGTAAAAAAATATTTA
+AAATTCTGCAAAATTTGAAAAAAATCGTTTAAAATTCAGCCAAATTTCGA
+AAAAAAAAGCATTAAAAAAGAGAAAAATTGGAAAAATTCTGCACAATTTT
+TTAAAAATTATTATTCTGAAAAAATTTAAAAATTCATGGAAAAATCTGCA
+AAATTATTTTTTAAAAATCGTTAAAAATTCAGCAAAAATTGGAAAAAAAT
+CGTTTAAAAATCAGCAAATTTCGAAAAAATAAAACATTAAAAATTCAACA
+AAATTAAAATTAGAAAATCATTAAAAAATACAGCCAAACCGTAAAAAATC
+AGCAAATTTCGAAAAAAATTCGTTAAAACTTCAGCAAACTTCTAAAAAAA
+ATCATTTAAAAATGCAGGAAATACGAAAAAGAAACATCAAAAATTGAGAC
+AATTGGAAAAAAAATTCGTTAAAAATTAACCCAAATAAATTTGCTGAATT
+TTTTAGATTTTTTTTTTTATAAATTTGCTGAATTTTTGAAAAAAATTCAG
+CAAATTTATTTTAAAAAAATCTAAAAAATTCAGCAAATTTCTTTTTTAAA
+AATCGTTAAAAATTCGGGAAAACTTGGAAAAATTGTGCAAAATTCAGAAC
+AAAAAAATTTCAAAATTTTCCCAATTTTTAAGTTTTTATTTAGTTTTCAG
+AATTGTTTAATAGTGAAAAAATCATAAAAAATTCAACAAAATTTAAAATT
+CAAAATTTTCCAGAATTTTCATGGGTCCCGCCACGATCCACTCCAACCTT
+CAAAAAATCATGTAATTTCCAGGCGTTGCGGCTTCCCAAATCGGCGGAAT
+CACACTTCACGCGTTTTGCGGTTTTCGCTACGAAAATTCGACGCCTGAAC
+AGTGCCTAAAACAGGTTTTACGCCAAAATCACATGGTCCGACAGTGGAAA
+CAATGCTCACACTTGATAATTGACGAGATTTCCATGATTGATCGCGACTT
+TTTTGAAGCTCTCGAATATGTGAGCTCATTGCGTTTTGATCTACAAAAAA
+TGCGGGAGTTTTCCCAGCATTGCTCATTTGATCTACAAAAAATGCGGGAA
+TTTTCCCAGCATTGCTCATTTGATCTACAAAAAATGCGGGAATTTTCCCA
+GCATTGCTCATTTGATCTACAAAAAATGCGGGAATTCTCCCAGCATTGCT
+CATTTGATCTACAAAAAATGCGGGAATTTTTCAAGTGTGACGTCAGCACA
+CTCATGCGAAATCTGCTGAAAAGTCTGCGTCTCTTCTCCCGCATTTTTCG
+GAGATCAAACCAAAATGGGACCCGAAAATTCCAAAAAAAAATCGATAATT
+TCCCGTCCCAGGTCGCCCGTACCGTCCGTAATAACGATAAGCCGTTCGGT
+GGAATTCAGCTCATTATCACTGGAGATTTCTTTCAATTACCGCCCGTCTC
+GAAGGATGAACCAGTTTTTTGTTTTGAGGTGTGCGGAATTTCGGAGCATC
+GTTTGGACCGTCTAACTCTTAAAAAAATTTTTTTGCAGAGCGAAGCCTGG
+AGCCGATGTATCCAAAAAACGATTGTCCTGAAAAATGTGAAACGACAAAA
+TGACAATGTTTTTGTGAAAATTTTGAATAACGTTAGAGTTGGAAAGTACG
+TAAACTACTGGAAAAATTTAAAAATTTCGAATTTTTCAGGGTTTTTTACT
+AGAAATTTTGATTTTTTTCAGTGAAATTCCAATAAAAGCTGGAAATTTTC
+AGAAAAAAGGAAAAAATATGAAAATTTGTAATTAATTTCGAAAAATGCTG
+AAAATCTCCAAAACCTTCCAGAAAAGCTGGAAATTTCATAAAAATTTGGG
+AAAATCTGAAATTTTCAGAAAATTCAAAAAAAGCAAAAAATCTCGAAAAC
+CTTCCAGAGAAGCTGGAAAATTTCAGAAATTTCCAAAAAAATAAATTCTG
+AAAATTTCATAAAAATCACTGATTTCTGTCTTCCCTCATAAGTTGAAATG
+GAAGAGTTTTTGCCGAACTAGGCCATTTTGGTTCGGCCAGATCTTGGGTA
+GATTTACGGCGCGTTGCGTGTCGCGTCGCGGCTCGATTTTAGTTGTAAAA
+TTAAATGTATTAGTCCGTGTGGAGTACACGACACTTTCCCACGTGTTGTC
+CGGCAGGTGATTGTCAATGGAGCGCGAAAAATTCAACGAGGAAGGCCAGA
+ACCCCGTGATAGACCGGCCAACACGGGGTTCTGGCCTTCCTCATTTCATT
+TTTCGCGCTCCATTGACAATCACCTGCCGGACAACACGTGGGAAAGTGTC
+GTGTACTCCACACGGACAAATACATTTAGTTTTACAACTACTAATTGAGC
+CGCGACGCGACACGCAACGCGCCGTAAATCTACCCCAGAAATGGCCGAGC
+CAAAATGGCCTAGTTCGGCAAAAACTCTTCCATTTCAATTTATGAGGGAA
+GCCAGAAATCCGTGTGAAATTTCCAAAAAGAAGCTCCAAAAAAAAATTCC
+AAAAAAATCTCGATAGCCTTCCAGAAACGCTGGAAATTTCAGAAAATCTC
+CTGAAATTGATAAAAATTCGAAAAAAATCTCAAAATTGTTAGAAAATCAG
+TGAAAATTTGGAAAATTCAGAAATTAAAAAAAAAATTTTTTTTTGGAATT
+TAGAATTTAGAATTCTTCAAATTGTCGAAAAATGCTCCAGAAAACTTGTA
+AAAATTTAATTTTTTTTTTTTTGAAATTTCCAAAAAATTTATTTATTTTT
+CAGATGCGACTTCAAATCAGCGGATATTCTAAAGGAATCCTCGAAAAATC
+AATTCCCATCCAGCGTAATTCCAACCAAACTGTGCACACATTCAGATGAC
+GCCGATCGAATTAACAGCTCAAGCATCGAGACAACACAAGGCGACGCGAA
+AACCTTCCACGCCTACGATGACGAGAGTTTTGACACGCACGCCAAGGCCC
+GAACGTTGGCACAGAAGAAGCTTGTGCTGAAAGTTGGAGCTCAGGTGATG
+CTCATCAAGAATATCGATGTGATCAAGGGACTTTGTAATGGGTCACGTGG
+ATTTGTGGAGAAATTCTCTGAAAACGGGAATCCTATGATTCGATTTGTAT
+CGCAAGCCGATGCTTCCATTGAGGCACGTTTTACAGAAATGACCATTTTA
+TGGGCGTGGCTTTTTTTTTGGAAAATTTTTTTTTTCCAAAATTTCTGGAT
+TTTTCTCTAAAATGGAAAAAACCCACGAAAATTGTAAAAAATTTGAAATT
+TTTTAAATCGGAAAAAAATAAAATTTTCTTTCTTAAAATTAGGCTTAGGC
+TTAAGCTTAGGCCTGGGCTTAGTCTTAGGTTTATGCTTAAATTTGAAAAA
+AAAAATTTCTAATTTTTTCCAGATTTTTCCGTTTTTTTTTTCAGAGAAAA
+TCTAAAATTTTCGATTTCTACCTGTTTTTCAAAAAAAGTTAAAAAAAACA
+TTTTCGCAAATTTTGTAGAAATTTTTCTTTTTTTTTTCTTAAAATTAGGC
+TTAGGCTTAGGCTTATGCTTAGGCTTAGGCTTAGGCTTATTCGTAGGACT
+ATGCTTTGGCTTAGACTTAGACTTAAGCCTAAGCCTAAGCCTAACCCTCT
+TAAAAAGTTACAAGAAGGTTTTTCCTTGCGCTTGGAGCGCAAAAGAAAAG
+AAAAAGAGCTATTCAGACTTAGGGTGCCCAACTGGAATAAAACATTGGAA
+ATCCTTATGACACACTTAAGCCTAAAGGCCCGAAAAACATACTAGGATGC
+CCAACTGGAATAAAATATTGGAAATCCTTATGACACACCGGCGGTATGGC
+GCGGCTTAAGCCTAAATAGCCACTTTTATCAAAATACATTTGAGCTCGTC
+TTGCGTTTTACTTTGACTTCTCAGGCAACTCAAAAGTAATCTGTGGATAT
+TTTTCAGTAATCTAAATGAAGACTATAGATTACTAAGAAACTTGGAGATT
+TCATAATATTTGGGGGGATGCGAGCATCCATTGGAGATTTGCCATTTGAT
+AGAACTTTTAGCGGCAAAAGTCCAAAACAAAGCTCACAGTGGGCTCTCAA
+AGATCATAAAATAGCACTGTAACGAAGAACTTTAACGATCTAACGAAGCA
+ATTTTACAAATTCACTTTGGTAGCTCATATCTCCGTGGATAAAATTTTTA
+CAGAAAAGTCATCAACTGATAAGTTGTTGATATTGTTGTAAAGAACAAGT
+TTGTAGTTGAAAGTTTTTTTTACCAAAAAATTTTTGTTTGAGAGAAAAGC
+ATTAGAAACGGAATAGCATCATAAAAATAACAACAGCAGTTGCCGCACTT
+CACGCGGTTCTATCTCAAACAAAAGCGGAGATATGAGCTACCAAAGTGAA
+ATTGGAAAATTGGCCCTCCAATGCTTCGTTAAAGTGCTATTTTCAGGATC
+TTTGAGAGCCCGCCGTGAGCTTGGTTCTGGAGTTATATTGATCAAATTGA
+CCCTCCAGTAAAGGAGGACCTTTGATGAATATAATCACTCTGATGGTATT
+TAATTCCGATGAGTAATCCATTTTTCTTTTTCTCACATTTGTGAACCAAA
+AATAAGTTTTAAATTAAGGCGGGATATTCTAAGGTGTGATAACATATGTT
+ATTTATTTTTAAATTTAAATAAAGTTTTTTTTTAATTTTTGCTAAAAAAC
+GAATAGTTTACAACCGCCTCGCTCAAATGTATTTTGATAAAAGTGGCTAT
+TTAGGCTTAAGCCGCGCCATACCGCCGGTGTGTCATAAGGATTTCCAATA
+TTTTATTCCAGTTGGGCATCCTAGTATGTTTTTCGGGCCTTTAGGCTTAA
+GTGTGTCATAAGGATTTCCAATATTTTATTCCAGTTGGGCATCCTAGTTT
+TTTTTTTTCGGGCCCTTAGGCTTAAGTGTGTCATAAGGATTTCCAATGTT
+TTATTCCAGTTGGGCACCCTAAGTCTAAATAGCTCTTTTTCTTTTCTTTT
+GCGCTCCAAGCGCAAGGAAAAACCTTCATGTAACTTTTTAAGAGGGTTTC
+ATATATTTTATTAAAATCGGGGCGAAGCCCTGATTTTAAATCCATATTGT
+TTTTGTTTTTGTCTTCCACTATCCCTGCAAATAGGAAAGAGAATGTGTTC
+TTTCTGATGAAGTAAAAATCATCATAAAATCTTGAAAACTGAGAGCAGGA
+GGTAATATTTGAATATATTGGGTTGTAAATGTGTGTCTCCCTGTGGGTGG
+GGTGGCGATGTGTTGGCAGCCAATCCTTCAACGAACTGTATCTCCCGCCT
+GTATCTCCCTTCAAAGTGAGAATTGGGTTACAAAAATTTGAGGGAATATG
+AAAAAAGGTGTGAGGATTTCAAAAATATTATTGTTGAAACACCAGACCAA
+ACCACTTTTTCTGGGCAAGAGACAGAAAATTAATTTTTTGAAAAATTTCA
+AACTGGCACAAAATTTTTTCAAAAACAAATTTTCACAAATTGTTAAAAGA
+TGCCATTTTTAATCAATATTGTTCATTGAACACAGAAAAGAAAACGAAGA
+TTCATCAAAAAATGAGTGAAAAATCGCAAAAATTCGAAAAAATCCGTGCT
+GAAAAACTCGAGTTTTTGGCGGTGCTGAAAAAAATTTTCACTAAAATTTT
+TTTGAAACTTAGTTTTTCGGATTTAGCGTCAAATTTTGAATCTATATAAA
+AAAAAAAATTAAAATTGATCTCAGATTGAGTGAATAATAAACGCTCAAAG
+TTGAAAAATGAACAACGCAAAAACGGCAGTAACTTGCTTCAAGGTCGGTT
+GTCTCAGTGAGTTTTCACTCAATTTTCGAAATTTTTTTGCTCTATCGCTT
+TAGAAATATTTGTAATTTCATTTTTTTTCCTCAAAATCAAAATATCTCAA
+ACGACCGCCATCCTACGAGAAGGGAAAAAAAAAGTTTTTGGAAAAAAAAT
+CAAAAATTTTTTTTCTGCCTCGATTTTCAAAATGAAAAAATCACTTTTTC
+GGAATAAACTTTTTCACAAATGTATTTTGATAAAAGTGGCTATTTAGGCT
+TAAGCCGCGCCATACCGCCGGTGTGTCATAAGGATTTCCAATATTTTATT
+CCAGTTGGGCATCCTAGTATGTTTTTCGGGCCTTTAGGCTTAAGTGTGTC
+ATAAGGATTTCCAATATTTTATTCCAGTTGGGCATCCTAGTTTTTTTTTC
+GGGCCCTTAGGCTTAAGTGTGTCATAAGGATTTCCAATGTTTTATTCCAG
+TTGGGCACCCTAAGTCTGAATAGCTCTTTTTCTTTTCTTTTGCGCTCCAA
+GCGCAAGGAAAAACCTTCTTGTAACTTTTTAAGAGGGTTAGGCTTATGCT
+TAAGCTTAGGGTTAGGGTTAGGGTTAGGCGTAGGCGTAGGCTTAGGTTTA
+GGCTTCGGCTTCAGGAATATTTAAAAAAAAAATCGAAAAATAGATTTTGC
+GAAAAAAAATCGTGATAAAGCCTGCTAAAATTTTCAAAAAAATTAAATTT
+TTCAAATTTTTCAAATTCCCAAGATTTTGGTCTCGCAGCGAAAACATCCA
+ACTACAGTAACCCTCGCCCTCTCCAATTTTCAGATCCGCCGCTCCAAGTT
+CTCAGTCCGCATTCCCGGGAGTGATGCTCCGTTGATTCGCCGTCAACTCC
+CACTCCAACTCGCCTGGGCCATCTCCATTCACAAATCGCAGGGAATGACG
+CTCGACTGTGCGGAAATTTCGTTGGAGCGCGTTTTCGCCGACGGACAGGC
+GTATGTGGCGTTGTCGCGCGCACGATCACTGGCGGCAATTCGAATTATCG
+GCTTCGACGCGTCGTGTGTCCGAGCGAATTCAAAGGTGAACAGGGGATTT
+TCGAGATGGAAATCTATGAAAAATGGATGGATGGTGTTAGATATCTCCTT
+TTCGTGGGTTCTCTCACGTGGTGTCAGAGTGCCTCATTTCGGCTTGATCT
+ACTGTGTAGATCTACAAAAAATGCGGGAGATGAGGAGACTCAGACTTCTC
+AACTGGTTTCGCATGGTTTAGAACGTGCTGACGTCACTTTTCTCTGGGCA
+TAAAATTCCCGCATTTTTTGTAGATCAACCGGTAAGGGATCTCTCAGCTA
+CGTGGAAAATTATCGATTTTTTATCGAATTTTTTGCAGGTTATCGATTTT
+TACAAATCCATCGAGGCAGAATGCGACGACGAACAGGACTGGGAAGCCCC
+TGCTGCTGGACCAAGGCTCAAGCGAGTTCGATCGATTTAATTTTTTTTTT
+TAAATTTTTTTGTGATCTCCAAATGTTCTGTCTTTCTGTCTTCCCCCCCC
+CCCCGCCAAAATTCATTAACTGTTTTATTTCACAACACTCTGTATCATCA
+TAATTTTCACATAAAATTGGCTATTTCAATGTTGACGTCGAATTTTTAGT
+CCTATCAGCGTCATCGGATCTGAAAAAATGGAAAACTTGAACAAAAAAGC
+AGGGGGTGGCCTAGAAAGCACAAAAAAAACTCGGACACAGTTCAACGGAG
+GCAGTTTTTGGAAAAAAAAAAACGTCATTTTCGTATAGCCACACTGAAAT
+TGAAAGAATTCTGGCCGAGTTTTCCAAATTCTAGGCCACCATGCAAACCG
+ACATTTTGGGCGGAAAAGTGCCGGTGGCCGTGGAAGAAGGAAAAACTCGG
+CCACTCTTCTATGTACTCCTCTCGGAGAATTGTGTTTTCCATGGCCGAGT
+TTTTGTGTTTTCTAGGTCATGTCGGCATTTTTCTTAGTCAGTTTCAAAGG
+AAATACGATACCTGGTCTCGACGCGAAAATTTTTTAATTAAATCCAAAAA
+GACGTGCGCCTTTAAAAAGTACTGTAATTCCAAACTTTCGTTGTTGGGAA
+ATTTTTATCGATTTTTCGTAGTTTTCAAAAAAAATAATCAAATGTACACA
+GGGTTCTGTTCTTCCTTATTGATTTTTTCGCGCTCCATTGACAATCGCCC
+GCAGGATAACGCGTGGGAAAGTCGTGTACTCCACACGGACATCGAGACGC
+GACGCGACACGCAACGCGCCGTGAATCTACCCCAAATATGGCCGAGCCAA
+AATGGCCTAGTTCGGCAAACTCTTCCATTTCGATTTATGAGGGAAACCAG
+AAATCCGTGAGTAGTGAGAAAAACAACGAAAAAATCGATAAAATTTCCCA
+ACAACGAAAGTTTGAGATTACAGTAGTCTTTAAAGGCGCACACTTTTTCG
+CATTTAACATAAATTTGTCGTGGAGAGAGTATTTTTGGCGCAAAACTTCG
+CATTCGGGTAATGATAATAGAAGAATTGAAACTCACAAATTCTCCGCCGT
+CTCCTCAAGCAGCAGCGGCACAATAAACATGAAATACACGGCCAACACGA
+AATGAATCGGCACCATCGACACAATGAACAACGACATTCGGAGCATGTGC
+TCCAAAACTGTCGGCCGCAACTTTTTCGACGGATTCTCAAAGACGAGATA
+CACTTGCATCGGGCTGTGCACATCTTGAACCGACTTCTTCTTCATTACAG
+CGCTCCCTTCTCTGGGCAGCAGGTAGCGTGTCCACGTGGTGTAGGGTGAC
+TCAGTGGTTGTGTGATTTATCGGCGTGAGCTGGAGCATTTTTGCAGAGTC
+GCAGGCCAAGGTAGCGGAGGTGTTGGCTCTGAAAGTAGATTTCATACAGG
+ATGGTAATTTCGGGGAGTACTGTAGTGGTGTTATAGTGGTACTGTAGGAG
+TACACTGTAGGGGAACTGTAGGGGTGCTGTAGCAGTACTGAGGGGGGTAC
+TGTAGGAGTACTGTAAGGGTGCTGTGGGGGTACTGTAGGAGTAATGTGGG
+GGTACTGTAGGAGTACTGTAGGAGCACTGTAGGGGAACTGTAAGGATACT
+GTAGGAGTAATGTAGATGTACTGTAAGGGTACTGTAGGGGTGCGCTAGTG
+ATACTGTAGGGATCATGTAGGAGTACTGTAGAAGTCCTGTAAGGGTACTG
+TAAGGGTACTGTAGAGGTGCGCTAGTTGTACTGTAAGGGTACTGTAGGGG
+TACTGTAGGTGTACTGTAGGAGTAAAGTAGATTAACTGTAAGGGTACTAT
+AGGGGTACGCTAGTGGTACTGTAGGAGCACTGTAGGCGTACTGTAAGGGT
+ACTGTAGATGTACTGAAGTAGTTCTGTAAAAGGTACTGTAGGGGTACTGT
+AAGAGCACTCTAGGGGCATTGTAGGGGTACTGTAGGTGTACTGTAAGGCT
+ACTGTAGATGTACTGTAAGGGTACTGTAGTTGTTCTGTAAAGGGTACTGT
+TGGGGTACTGTAGGTTTACTGTAAGGGTACTGCAGGGGTGCTGTAGGGAT
+ACTGTAGGAGTACTGTAGTGGTTCTATAGGAAGACAAACTTTTTTTTGAA
+TTTACTCATCGGAGAATCTAATATTTTTCACCAAATCGATACACCATAAA
+AATTTTAGGACCCAAAGCTAAAAAAAAAAACCAACTTCTCCAATATCATC
+TCCATCAATTCCAGTTGTTCTGTGCAGTTCGCCATCCCTTCCTTCTTCAA
+TTCCTTCGCCCGATTCTCCAAATCGTCCACCATCTTCACACCCCGCCGAC
+ACGCCGTCTCCACATACCGTTCCGTACCAGCTTCCGCAATTTTCATAAGC
+TTCTCGACAGACTCGTTAAACTTGCGTGTTGGCTTGAACAAATGGGAACC
+TCGAATCGCCTCGGGAACCGGATTTCCACCTCCTTCCACCAGGAGGCTGA
+ACAGTGTCGTTTTCTGCCTGACGGCCTTAGCCAGGACGTGCCCATAGTTG
+ATCATGTAGATTTGCCCGTTTTCAGATATGTTGAATGTTTCAGCAGATGA
+GAACATTTGAAAATTATTTGATTGTGCGTGTTCATGCACCACAGTAATGA
+ATGCGAGGCGGCAAATTAAAACTCTGAAAGTTTAGATAATTGTACTTTAG
+TTGAAATCTACTTTGGTTGACAGGTGCATCGACTAGACTAAAAAAAAAAG
+CAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTA
+GGTAGGTAGGTAAGTAGGTAAAGCGAGACACGGTGCATCGATCTGACTTT
+AAAAATCTCAATCTCGTATCTTAAGCGTCTTTGGTTCTGTCAGGGAAGCA
+GGTAGGGGGGAGGTAGGTGTGATCAGGCAGAGCACCGGAGTTAATATCTG
+GTGGATTGTGGGCTGCTAATAGGTAGGTAGGCAGGTAAGCAAGCAAGCAA
+GCAGGCAGGTAGGTAGGTAGGTAGGTAGGCAGGCAGGTATCAGTTGACAA
+CTTTTTGATGAAACTAAACGGAGCCGAGTTATAAGGTGCCAAAGTTGCAC
+TAGACATGGTGCATCGACCTAACTTGAACAACTCGTATCTCAAGTGTCTT
+TGGTTCTATTTGGGAGGCAGGTAGGTAGGCAGGTAGGTAGGTATATCTTA
+GGTTGTTTCAAAACTATTATACATTAAAAATCAATAAAAATATTTTGCAC
+GAATTTTATCAGTTGACAACTTTTTGATAAAACTAAAAAGAGCCGAGATA
+TTGTAAGTTGCAAAAGTTGAACGAGACATGGTGCATGGAAGGTAGGTAGG
+TAGGTAGGTATTTAAGTAGGTAGGTAGGTAGGTAAGCATTCCGTATTTCT
+CTCTACTTTGACAGCTTATATCCTGGTTGTTTTGTGTTGTATCAAAAAAT
+GTTTAACAAAGATAACATAGAAAAATATTTAGCACGTAGCAAATTTAAAA
+AACTAGGTTGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGAAAG
+GCAGGCATGTAAGTAGTAGGTAGGTAAAAGTACTCACGTGGAGAACATCA
+AGCAGAAGATCGCTGAGCAAATTGAAAGTGGTACTGGAAGTTGAGCAAGT
+ATTTTGGAGTATTTTTCTGGAAAAAAATAAGTATTCAAAGTAACTAAAAT
+AAAATACCAACTCCGAAACTCAAACTTCATAATAAACAAAATCGTCAGAA
+TCCCACTGGAGAGGACTGCAAAAGTCACTGTCGTGTTGGCAGACGTCTGA
+TAAAAATCGAGGGTGTGTCCGGATGGTAGGAGAAGCACATTATCGTGATA
+CTTTGACACAAATTCCTCAATAGACGCCAACGCTTTTCCGAAAACTGGAA
+TCGAAATGTTCAAAGCATTGAGAATTATTTTCTGGTACTCTTCCACCAGG
+ATGTTGTACTCCGAGTTTAGATCCGCTGAAAAATTTAAATTTGTATTAAA
+TTGGGCAATACTCGTACTTGCCTACCTGCCTACTGGTAGGTAAGCAGCCT
+ACTTATTTTCAACTTACAAAACTCCATATACTTTGTAACGTTTTCCAATT
+TCGCAAAAATCGATTTCTCGAAATATTTGCACTTCCCCTCGACAAATGAT
+TTCTTGGCGGGAATCTTCAGGAACAGCTGAAAATTTTTTTTTCCGGTGGC
+CGAGTTTTTTCACGGCCACGACGTACCTTATTAAACATGGTGAAGTTGGC
+GTAGTCATGCAAGAACCAATTTATTCGGCGGCGTTCGTTTTCGGTGACGG
+CGAAGTCTCGTTTGAACAAGCACGGTATGTAGGACAGCTTACGGTGGAGA
+CGCTCTTTGATGGCTGGAAGTTATGACGTCATGAATAATAAGGGATGAGA
+TTTCTAGGCCACGTGTGACGTCACAGCAATCCCCGAAACCTTTTTGGATG
+GCCGAGTTTTACCGATTTCTAGGTCATCGAGCGAAACTTTTGTGATACTT
+TGGCAATGGTCATCAGGTAGACAAACAACGTGATAATTTCTAGGCCACGC
+TTGACGTCACGTGGCCGAGATTTCGCGCCAGGACCTAGAACTAGACATGG
+TGCATCGACCTAACTTAAACAACTCGTATCTCAGGTGCCAGGTAGGTAGG
+TAGGCAGTCAAGCAGATAGGTAGGTAGGCAGGTATTTTAATTTCATTTCT
+GCGGCTACAACACAATTTCTCTTCCAATCAAGGACGTAAATTTCTAGGCC
+ACACATGCAGAGTGCGGACTAATAATTAAAGTGTTTTACGACATGGCCGA
+GAAAAGAGAAACCTAGGCCATGGTAGTTAGGTGTGACGTAACGCCACTAT
+AAAACTATAAAACTCACGCATAAAACTGTGATCATTGGCGGTTTCGAGCA
+TCGTCCTTCCATAGACCGCATCCTGAGTACACTCTCGTAAATTGGCGGCC
+AAAATTGTTAGACCAAGGATACAAAATATGGGGATAATGGTGAATCCGGA
+GCGATTATCATCCAACCAATACACGATTACTTCGATAACCTCGAAGAGCA
+GCAATTTCCAGACGACGAGGAATATCAGCAGAGCTGTGATCAGGCAGAGC
+ACCGAGATTATTATCTGGCGGATTGTGGGCTGAAAATAGGTAGGTAGGTA
+GGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAGGTAAG
+TAGGTGGTAGGTAGGGAGGCAGGTATCAGCTGCCAACTTTTCGATAAATA
+TTAAACGGAGCCGAAATATAAGTTGCCAAAGTTGTACTAGACATGGTGCA
+TCGACCTTACTTAAACAACTAGGTAGGTAGGTAGGTAGGCAGGCAGCTAG
+GCAAGTAGGTAAACTCACCAAATGCCTGAAAACAATTGCAAGAACATCGG
+AATAACCCGAGCTCCTCCCGTTCAACGTCGCGACCACAAGCGCGTGCACA
+CTTTTCCGCAGCTTCTCATCATCGCGATCAGCGCAAAAATCCTCGATTAT
+CTCGAATCGATGGCTCTTTTTTGTGTGCGCCGGGTCTAATTTATAGCTGA
+TCGGCTCGGGAAACCAATCGTCACACTGCAGCTTCGCATCCTCCAAGCTG
+AAGCCGTGAGAAAACTGTGCACTGCATAGGAATAGAAGTAATTTCAGTTT
+CATTTTGTTCTGGAAGAAGGCATTTTTATGGATGGAGTTTGAAAATAATA
+ATTAAAAAAAAAACTTACAGCTGGAACTTTGTGAAATCGATAATGAAACA
+ATAAATCTAAAAAAAGCTCAAAAAATTTTTGACAAAATTTAAAACTGTAA
+CGTGTATGAAGGTCACGTGAAAACTGAAAACTCACCAAAAATGTCGAAAA
+ATAGCAAGAAACTAGGCACACGTAGACTTATGGTAGGCAGGAAGGCGTAG
+GCGTTGATCCAGGCAGGGTCACGTCTTGAAGGCAGACTGTTAGGTATAGG
+TAGGCATAGGTAGCCATGTAGGCGTAAAGGCAGGAAGGCATCTCTAGATC
+CTTTTTGTGGCAGATTGGCCGCTTTGCAGGCAGGCAGGTGTGGGTGGCCT
+AGTAGACCGAAAAACAAGCAGGTAAAGTTCCTATAGTAGTAGGTAGGCGA
+GCCAAACCTTTTTTGTAGATGATGAAGTAGGTGTAGGCCGTCTTTTGAAG
+GCAGTGAGGCAGACAAGGTTAGGTCGTCGCAAAGGTTGGCTGGAAGGTAG
+GCACGTGGGTCAGCAGATAAGCGTAGGCAGGCATAGGCAGGAAGGCATAG
+GCAGGTAGACGTAGGCAAGTAGACGTAGACAGGATAAGATTCAAATATGA
+AAATCGTGAAAAGGGGAAAATTTCTTATTCTTCGAGTGCGCGACAGTATG
+CGTAGGCAGGTAGGCGTTGGCAGGTAGGCGTAGATAGGTAGGCGTATGCA
+GGTAGGCGTAGGCAGGTAGGCGTAGTCAGGTAGATAAGCAGGTAGTCGTA
+GACCGGGTAGGCGTAGGCAGGTAGGCGCATGCAGATAGTCCTAGGCAGGT
+AGGCGTAGGTACGTATGCGTTGGCAGGTAGGTGTTGGCAGGTAGGCGCAG
+GCAGGTAGACGTAAGCAGGTAGGCGTAGGCAGGTAGGCGTAGGTAGCTAG
+GCGAAGGCACGTAGGCGTAGGTAGGCAGGCATAGGCAGGTAGGAGTAGGC
+GTAGACATGCGCACATGAAAACCTTATAAATGTTTCAACCCCATCATCAT
+CATCCCATTTTTCTCTCGATCAAAACGAAAAAATGTGCGCAAACACAAAT
+TGCATCCATTTCTCTCTCTTTTTTACTCACTTATATATCTCTCATCACTT
+TATCCCCCGTTTTTCAATCCCTTCCAAACACTTCCAAAACTCTCCAGAAC
+TCCTAGAGAGTAACACGAGAGAAAATATTTGAACTTTTGTCTCGACCAAG
+TTTTTTTTTTTGGGATTTTTTCTTTGGATTTCTACAAATTTGATGTATTT
+TTTCCATTTTTCGTGCAAAATATGGTAATGGACTAGGTTTTTGCTACGTG
+GCCTAGAAAAATCTCGGCCACCGATTCTGAGCTGTTGCAGCGGCCGCGGC
+CGAGGGTTTTTCTCTTCAATCGATACCAATCCCTCTTTTACGCAAGGAAT
+CACGTGGAGTCAGAGTGTCTCATTTCGTCTTGATCTACGTAGATCTACAA
+AAAATGCGGGAACTGATTTCGTATCGTTAAGAACATGCTGACGTCACATT
+TTTTTATCATAAAATTCCCGCATTTTTTGTAGATCAAACCGTAATGGGAC
+AGCCTGGCACCACGTGCTCTTCCAACCTTTATATTTTTTTTGACAAAATC
+TTGAGAATTTCTAGAATTTCAACGAAAATCCAATTTTATACCTAAACTTA
+AAAAAAAATTGCTAAATTGTGTTCGACTAGCAAAAAATGCACCCAGTTTT
+ACAAAAAATCTTTTTTTCTGAAAAAAAATTCAGTGGAAAATGTCTATAAT
+TTTCAGTAATTCATACTAAAAAAAATCCAATTTTTACAACAAGTTTTTGT
+GGCCGCGGCCGAGGTTTTTCCTCTTCCACGTGGTGTCAGAGTGTCTCATT
+TCGGCTTGATCTACTTAGATCTACAAAAAACGCGGAAACTGATTTCTCAT
+GGTTAAGAACGCGCTGACGTCACATTTTTTTGATCGTAAAATTCCCGCAT
+TTTTTGTAGATCAAACCGTGATGGGACAGCCTGGCATTACGTGAAAACAA
+ACAATGCAAGCGCGCTCTAATGCGAATTTATTTGCTCTACCACCAGATAA
+ATTCCACTTCTTCACAATAAACCTAAATATTTTTTGTGTCAAAATCTTGA
+GAATTCTTAGAATTCCAGAATTTCAGCGAAAACCTAATTTCCGATTTTGT
+TATTGTTCAGGGGAACAAGTGAGCCACACAGCTTCCGCTTCTGCTCCGAA
+TTCGATTCCCCTGAGGCATTTTTGTTCGAAAAAAGCCTCATTTGTCATAC
+TTGTCGGCAACTTTCTTCGAAGTTTTTGTTCTTGTTTCAAATAATTTTTC
+TTCAATACTTGTTCCTTCCGTCCCAGCAGATGTTCTTTTGCGGGGGGGGG
+GGGGGAGGGGAGAAAAAAAATAAGAGAAGAAGCAGAAACTCGACACTTTT
+GTGTCCGCATTTCTCGTAAAGTTTTCAGATTTTTGAGCTTTTCAAGCTAT
+AGCTGAACCACCTAGCAAATTTCGCCGCAGAGTTGATTTCTCCGGGAGTG
+GGCTTTCTACTGGAGACCTCACTTTTTTTGCCTTTTACTAGAGCTTTTTA
+ATTTTTTAATAATTTATTGCAGCTCTATGGATTTTCCAAAAAAAACCACC
+GAAAAGCCCGAAAAATCAAAATTTTCGTTTTTAAAACCCTAAATTCCATA
+CTCCGTCCAAAGAACACTCACATAAAAATGAAGAGATTTCGCAAAAAAAG
+TGAAATCCAATTCAATTTATTTCAATTTTGAAGAGTGCGTTCGTCAGCTT
+TTTTTTCGACAAAAAAAAAAGAAAATGTGTAGTGTAGTTTTCAACAGATT
+TATTGTTTTATTAATATAATAGAAATCAAACCTTCTTTCTGCCTACCTAC
+ATGGCTACCTACATGCCTACTTGCAAGTAGACCTGTCTATCTAGGTACTT
+ATCTCACACCTCTTTACCTACATACCTACCTTCCTACTCACCTGCCTACT
+CATGTAGACATAAGTGATCGTCAAAAAAGAAGCTGATGGATCAAAAGTTT
+TTGGAAATTTATTTCGATTTTCAGGTTTTAAAAATTGCGGAAGATGTTTA
+ATTTTTGACGATTAGTTTAGAATTTTTTTTAATTAAGAAAAAAAAATTAT
+TATTTTATTTTTAAATTACTCCAAATTTTCTTCTGATTCCGAATATCTAT
+GTGAAACTTTTTTTAATTCCTTGGTTTTATATCTAAGCTTAAAATCGCTA
+ATTTCATTTGTGCACCCAAGAGATTTCGAATTTTCACGGGGTTCTGGCCT
+TCCTCCTTGAATTTTTCGCGCTCCATATAATATTGACAACCGGGCAACGC
+GTGGGAAAGTCGTGTACTCCACACGGACAAATACATTTAGTTTTACAACT
+AAAATCGAGCCGCAACGCGACACGCAACGCGCCGTAAATCTACCCCAGAT
+ATGGCCGAGCCAAAATGGCCTAGTTCGGCCAAAACTCTTCCATTTCAATT
+TATGAGGGAAGCCAGAAATCCCGTGTAATTTTCGCGCCAGAGACGCCATG
+TGTCGATTTACGAGATTGGTGTATATTTACAAAATGCGTAATATTTATAG
+AATGCTGATTTCCGTTTTTTTTTTTTGAAAAATGTCATGTGTGCACAAAT
+TAAATTCGGCGATTTTAAGCTTAAATATAAAATCAGGGAAATTTTTTAAA
+TTTTTTTCACGTAGATATCCGGAATCAGGGGAAAATTTGGAGGCAATTAA
+AAATGTCTCCCTGATCATTTAAATTCTTTAAAAGTACTCTTCAGAATCCT
+TTTTTCCTAACCAAATAAAATAATTTCTGACGCCTTTTTTTTCTCTTTTC
+AATAAGAAGCAAAAAACAGACGAACCTATTCCAATTTCCCACCACACCAA
+TTCGTTCTTTCCGCATTCTTTTTCTTCCATTATTTATCTCCCTTTTCCTC
+CATTCTCTGTGCTCTTATATATATCCATCATCCCATTTTCTTTCTTGTTG
+TGTGGTATGCTCTTTTTCATCCATTATTCGAAAATTCTCATTTTCCAAAG
+TTTTTTGTCAAATACATTTTAAAAATTTTTTAAACCAAATCTCGCCGTCC
+ATCGATTTTAAAATACCTTTTTTGAGAAGTTTTCAAGAAATTTCATTATG
+AAATTCGGTGTTTTCAGACAATTTTGAGTCTAATAAAACAATTTAAAATT
+TTGACTACATCACCTTTAACTTGTAGAATGCCGTTTAAACACACTTATCA
+CTTTTTCAGAATCCCATATGCAATGGTATCACTTGCTCCTGCTAATTCTC
+ATGATCCTGGTCCTAATCCCATGTTTCTGGCAAGCTTGGCTACGATTTTC
+CCGTCGATTCTCCGATTCCTATGATCTATCAAGAAATGCGCAAAAGCGTG
+ATGAGATTTCAAAGGAGTTTTATGTATAGCTTACTGACAGGATTTCAAAA
+AACAGTTACGGTAAGATTTTTCGAAAAATTTCACGGATTTCTGGCTTCTT
+GCCGAACTAGGCCATTTTGGCTCGGCCATATCTGGGGTAGATTTACGGCG
+CGTCGCGTGTCGCGTCGCGGCTCGATTTTATTTGTAAAACTAAAGGTATT
+TGTCCGTGTGGAGTACACGACTTTCCCACGCGTTGTCCGGCAGGCGATTG
+TCAATGGAGCGCGAAAAATTCAATGAGGAAGGCCAGAACCCCGTGCCTGT
+ATAGGATATTTTGAATCTCAAAAGAATTTGAAGATTTGAGTTTTTTGAGT
+TTGAGGTGGAAAAAATCGTAAAAAATTCCTTTCCGATAAATTTTCGGATG
+CAAAAATGTGATCCATGCTGTAAAAAATCCAAGAAAGCCAAGAAATGTGC
+GGAGCCTATTTTCCGATTTTATATTACTTTTTATTTCAAAACTTGATTCA
+AAAATATCAAATTCGGAAAAAAAACCGCAACTTGGTAAAATTTCCTCGAA
+AAATATTCTCCGCTTAGGCTCCGCCCCTCTCTTGGCATTTCGAATTTTTT
+CGTTAAATTTTTGGAAACTGAAATTAAGTCCAAAAAGAACCAAGAAACGG
+GCGGAGCCTATTATGGGATTGAAAAGACATGGTGCATCGATATGGAAACG
+GCTTTTAATTTGGTTTTTTTTAAATAAGAAACTAGTAAAATTCAAGTGGC
+CTAGCTTTCAACTCTTCCATAATTCCAGGGTACATTCCAACTGGTCATTG
+CTCATTGCTCTCTCTTTATGCTTCTCATCACCAACGAATCCACTCAATTT
+TCACTCAAGCTGTCATCTCCAGCAGTGTCTCTCAATTTAATTATGCTTGA
+AATTGTTTTATAAAATGAAACAACACATACTCTGTAAAAGCAATTTATTA
+TTAAAAAGTATATATATACACGTATTCCTGGGTGGGTATTGAGACTAACG
+GAAGCGACATGGAGGAGAATTTGAATTTCATTAAAAAAAAAAAACAAAGA
+GGTAGGTTACTGTAGCATCCAATCTGGAGGCTGCACAAAGAAGACTCCAC
+CGTCAGTGGCGCAATATGTTGGACACACCTGGAACGTTGAAACATTATTT
+ATTTCTTTAAAATTTTCTTTGTCTAAGCCTGAGCCTAAGCCTGAGCCTAA
+GCCTAAGTCTAAGCCTAAGCCTAAGACTAAGCCTAAGCCTGAACCTAACC
+CTAGGCCTAAGCCTAAGAAAAAGCCTAAGCTTGAGCCTAAGCCTAAGCCT
+AAGCTAAAGCCAAAACCTAAGCCTAAGCCTAAGCCTAAACCTAAACCTAA
+ACCTAAGCCCGAGCTTAAACCTGAGCCGATACCTAAGCCTAAGCCTAAGC
+CTATTCCTAAGCTTAAATATAAACCTAAACCTAAGCCTAAGCCTAAGCCA
+AGCGCTGAGCGTAACTTAGAGCCTAAGCTGAGCCTGAGCCTAAAACTAAG
+CCTAAGCCTAAGCTTGATCTTAAGCTTAAACCTAAGCCCTGAAAATTTTT
+TTTTGAACTCCACAACAAAATTTGTAGAATGTTTTTAAAAATTGGGATTC
+TGAAATTCCCCGCCAAAAAGTTTAAAAACTTCACATTTTAATTTATCTGT
+AAAATTTATATAAATCCCTCTTAGATTTTGAATTTCGCGGCAAAACTTGT
+AGAACATTTCAAAAATTTACTTTCGCGCCAAAGATTGTCGCGCGAAATTT
+ACAATTTTTCTATAAAAAATGTATTTCATAGAATTTCAAAAAATCGAAAA
+TCGCGCCAAAAATTTTTAAAAATTTTTTTCAGTATTGTGACGTCATAGAC
+TACAAACTAACCCCTCTATTGCCTTCCTCCCCGTGCTCTCCAATGAGTCC
+TTCGGCTCCAGCGGCTCCATCATTCCCTGGGAACCCGGGCTTTCCTTTTT
+TTCCTCGTGGGCCTTGTGCACCAATCGGGCCGTCGATACCAGGCATACCA
+GACGGTCCTGGCGGCCCGAATTCTCCTTCCTCTCCGATCGGACCTGCTGG
+TCCCGGGATGAACGGTTTCGGGGTGGCGTCCGCACCCGGGTCGCCCATTT
+CTCCATCCAGTCCTGGGATTCCCTGAGGGCCTTGTAGGCCTTTTGGTCCC
+ATTTTTCCATTTTCCGCGCGAAGTCCATTCTTTCCGGGTAGTCCTGGCTT
+ACCAGTGTCTCCTTTCACTCCCTGAAAATTTAGTTTAGTGGTATAGGCCT
+ATCAAATAGGCTTACCGTAATCCCAGTGGTTCCTTGTACTCCTCTCGGAC
+ACGGATCCGCACACAAAGACTTATAATTCACAGGAGGCTCACATGGTAGG
+CGCGCTGGAAGTCCAGGCGCACCTTCCGATCCTTTCGTTCCAGGAAGACC
+GTCTCTTCCAGGGATCCCCGGGGGTCCTTGTGGATGACGGCACTCACATA
+CTCGGGATCTTGCGGTTTGGCCGGTTTCGTGTAGGAAATCGTCGATTTCA
+TCTCTTTTCTGGCGGGTTATGTTTTGGAAATCGTTGGCGACATCGGATAG
+CATGCTTTTCATCTCGAGGGCGCTTTCCTGGAAATTTAAATTTGCTTGAA
+ATTTTCAAACTTGTTATATTATAATTTACAAAATACTGACTGCCTTTGTA
+AGTTTTTTATTACAGGAACACAAAATTCTAAGAATGCGTACTGCACACTA
+TATTTGACGTGCAAGATATCTCGTAGCAAAATCTACAGTAACTCTTAAAA
+TGACTACTGTAGCGCTTGTGTCGATTTACGGGCTCGATTTTCGCAACTTT
+TTTTCTTTCGGATTTCCTTCGTTTCCTCGTATTGTTTTCTAACTTTTTAT
+TTCAAAATTTCAATATTCTATCGATAAATAAATCATTTTAATTTATTTCG
+AAAATCGAGCCCGTAAATCGACACAAGCGCTACACGAGTCATTTAAAGGA
+TTACTGTAGTTTTCGCTACGAGATATTTTGCGCGTCAAACATGTTGTGCA
+ATACGCATTCTCAGAATTTTGTGTTTCTCTAATACTGTGTTTTTAGGATT
+TTGAATGAAAGGAAAAGCCCGAAACTTTTAAACAAATTTTTCGGTGCATT
+CTGTATCAAAAAAGCTGAATAAAATTGTACAAAAAAATGCCACATTTTAT
+TGAAAAATTGATAATAAAATAATTTGTTTTCAAATAATTTTTGAATTTCT
+CAATTTTTTGGAATTTTTGGATTTTTTCGGGCCAGAAAGTAGGCATTCTC
+ATGAACTGATGTTTTCTTCATAATAATATATTCAAAAAAACGGTCTCCCA
+CAAAAAAAGGTCCGAGAGGCGAACAAGGTTGTAAAACGTTGCTATTGTTT
+ATTTACAACCGCCATTATACCCCTATAGGGGTTGTAACACCACATAACAA
+TTTGATAAGATGCACACAGTAGGGAGAGGGACCTAATTTAAAAATATAAG
+AATTTTCTCATTAAATACAATTTTTCTCTATTTCTTTCAGGAATATCGAG
+AGGAAAATCAGCGAAATTTTTGGAAATTTTTGGTTTTTTTCTAACGAAAC
+AAAAAAAATTTGAAAAATTTCAAGAAATTCTGTGTATTTATCGATAAAAT
+TTCAGAAATCAAGGGGGTCGTATAGAAGTTAGACGGTCGGTTTTTCGACT
+TTCAGCTAACTTTATGAAATTTCATTTGTTCAGGTTTTCTGACATTTAAA
+ATCAAATGGCATTAGCAGTTTTTCATGAAAAGTTTCAGAAAGTCTCAAAA
+CTCCAAATTTTAGGAGGGTCGTATAGAAGTTGGACGCACTAAAAAAAAAG
+GAAAAATGTGGTTCTAATTATTACGGAAACACTAAATTCTGAGAATGCGT
+ATTGCACAAAATATTTGATGCGCAAAACATCTCGTAGCGAAGACTACAGT
+AATTCTTTAAATGTCTACTATTGTAGCGATTGTGTCGACACGTGGTGCCA
+GATTGTCTCATTTCGGCTTGATCTACGTAGATCTACAAAAAATGCGGGAG
+AAGAGACGCAGACTTCTCAACTGATTTCTCATGGTTAGGAACGTGCTGAC
+GTCACATGTTTTCGGGCCGAAATTTCCCGCATTTTTTGTAGATCAAACCG
+TGATGGGACAGCCTGGCACTATGTGTGTCGATTTACGGGTTTGATTTTTG
+AAATTGATTAAAATAATTTAGTTATCGATATTATATTGGAATTAAACAAA
+AAGTGAGAAAATAAATCGAGCCCGTAAATCGACACTACAATAGTCATTTA
+AAGAATTACTGTAGTTTTCGCCACGAAATATGTTTGCGCGTCAAATATAT
+TGCGCAGTACGCATTCTCAGAATCCGTAATCCTCAAACTTCTCACCTGAC
+AGTACTCGGCATCGTTGACAGTATTCTGAATAGCCGGTCGAAGTATTGAG
+GCAAGGGGTCCTACAGAAACAATAAACGACGACATCGTGGATAGCGAGAT
+AAATAGTGAAACTATGATTAACGTGGCGTATGCCGTTTCTCGAGCATTCT
+CGTTCATTTTCCAGGAGAAGCCTCCAAGAGAAGCCTATGGAGGATCCAAC
+GAAAAGTGAGTAAAGAAATGATGCGCTGGCGCGGAAAAACGAGAGCGATT
+ATGTATGGGAGTGACCCAAAAACACGGAAAAGTAACGGATAACAAGAAGA
+AGAAGGGGGCAACTTTCTCTTTCTTATCATCATCACCATCATCATTATCT
+CCTTTCTCGGGATTCCGTCATGAGAATGAATCCATTTACTCGTTTTTTTT
+GTGTCCATTTAAGTTTGTCTATAAATATGGCTAATTTCAACTTTAAAATC
+AAATAATGAAACTAGTAATTCTACTCATCTCTCACGCAATTCCTTTCTTT
+TATGTGATATATAACTTTTATTCCATATTTAAAGAAATTTCAAGTTTAGA
+GTCTAACTTGAAAATTGCCAGTGATGAATATAAAATTAGAATGAAGAATA
+TTTCCAGAGAAGTTGGAAGTGTAGTCTTGGAGGAGAAGAGAGGAAAGAGG
+TGAGGAAAAATTACGTTTTTTTGAAGTTTTTTCTTTAATTTTCGAAGGAT
+TAGGCTTAGGCTTGGGCTTAAGTTTAGGCTTAGGCTTAGGTATAGGCTTA
+GGCTTAGGTTCAGGCTTAGGCTTAGGCTTAGGCTTAGGCTCAGGCTTTTG
+TTCAGGCTTAGGTTTAGGCTTAGGCTTAGGCTTAAGCTTATGCTTAGGTC
+AAAGTATAGGCTAAGAGGCCTAGGCTTAGACTTAGGCATAGGCTTAGGCT
+TAGGCTTAGGCTTAATCTTAGGCTTAGGATTAGGCTTAGGCTTAGGCTCA
+GGCTGAGGCGTAGGCTTAGACCAAGGCGTAGGCTTAGGCTTAATCTAAGG
+CTTAGGTGTCGGCTTAGGCTTTAGCTTAGGCTTAGTCTTAGGCTTAGGTT
+AATCTTAGGCTTAGGATTAGGCTCAGGCTTAGGCTGCGGCCTGGGTTTCG
+GCTTAGGTATAGGCTTAGACTGAAGCTTAGACTTAGGTTTGGGCCTAGAA
+TTAGGCTTAGGCTTAGGCTTAGGCTTGGGCGGGGCTGGGCGGATGAGAAA
+AAGAGAAAAATTCCAGGAAAATCCAAATAAAATCCAGAAAAAATAATAAA
+AAAAAGGAAAAAACGGGAAAAATGGGGCATTCCGCGTCTGCCGCGTCAAA
+AACTTTTCCTTAAAAAACGGACAGAGAAGGACCAAAAAAGACAAAAGTTT
+AACAAAAAATAGTTAAACATTTTTTTTGACGGGGTTGAGCTCACCCAGCT
+GAGCTCACTCCATAATTGCACACAAAATTCTCAAAAAATTAATTTTAGAG
+ACTACACAGAGGCTAGCAAATGCACATGCTCTTCAACGATTTCTCAGAAA
+TGCCCGCCAGGCTCCAAAGGTGCTCCAGGAGCCGATGGTCTGGACGGGAT
+CCCCGGCTCCAGAGGTCTGAATGGTATGGATGGAGAGGCTGGGCACAGTA
+ATATGGATGTTTGTGAGTTGCCCAAGATCTTTTATTTTTTGTAAATTCAT
+ATTCCAGTCATGTCACCAACAGGATGCATCCGTTGCCCAGCGGGTCCTCC
+AGGTTCTCCTGGTGATCATGGTTCTCCTGGTGAACCAGGGTACCCGGGAC
+CTTCAGGACCTCCAGGGGAACCCGGTTACGCAACAATTGGGCTTATCGGG
+CCACCTGGACTCGCAGGCCAAGATGGTCTAGATGGAGCTCCTGGCGAGCC
+GGGAGTAGGTGGAATGGATGCAGTGAAGATTGTTTCAGTTGATGGAAAAA
+TTGGAAGAAGAGGAGAAGCGGGGAACAAAGGAAGCAAAGGATCTCGAGGA
+GGAGTTGGAAAAGCTGGAGGGCCTGGGGTGGCTGGAGAAATGGGAGAAAA
+AGGAGCAAGAGGTGAAGATGGAAAGCCTGGAGAGTCTGGAAAGGTGAATT
+CTCAGAAGTTGATCGATGCACCAGGGCGACAAATTAAGCGAATCGGCAAA
+TTGCCGATTTGCCGATTTGCCGGAAACTTTCAATTCCGGCAATTTGCCGG
+TTTGCCGATTTGTCGGATATCAAATTTGCCGGAAATGTTTAGAGGGATTT
+TTTAAAAGACGAAAACACTTAAAACTGTGTCTTTTTGAATTTTTTCCCGT
+TTTCCTAACTAGGGAATATTGTTAATAGGGGAATTGCTAGGAAGAAAAAA
+CAAACTTTAAATGACAGATGAGGTCTTTGGCTACAAAAATCATTTTTTTC
+ATTATTTTCATTTTCATAGAATTTGCTCACTTTTCAAAATAGACGTAGGA
+ACATTCATAGGATGCGTTTAATTTTGCCATTTGAAATTTAAATTCTGAAA
+TTTCCAAAAAAAATCGGCAATTTGCCGGTTTGCAGATTTGCCGGAAATTT
+TCCATTCTGGCAATTTGCCGATTTGCCGATTTGCCGATTTGCCGGAAACT
+TTCAATTCCTGCAATTTGCCGGTTTGCCGATTTTCCGGAAATTTTAATTC
+CGGCAATTTGCGGATTGGCCGATTTGCCGGAAATTTCAATTCTGGCAATT
+TGCCGGTTTGCCGATTTGCCGGAAATTTCAATTCCGGCAATTTGCCGGTT
+TGCCGATTTGCCAAAAATTTTAATTCCGGCAATTTGCCGGTTTGCCGATT
+TGCCAAAAATTTTAATTCCGGCAATTTGTCGATTTGCCGATTTGCCGGAA
+ATTTCAATTCCGGAAATTTGCCGATTTGCCGGAAATTTAAAATCCGGCAA
+TTTTCCAAAACTGTATAATTTTTCAGCCCGGCGCACCTGGAATCCCTGGA
+AAAGATGGTACATACTGCCGATGTCCCGATCGAAATCGTTACGATATTTA
+TCCATATAAATCGAAAATCTGATAATAGTAATAAAGATAATAATACAATA
+AATACAGACAGGAAACGAAAAGCGAGCACTGACGATTGTATGATACCCGA
+AACATTAAGGAGGAGCACAAAAAACACAATGAAAAGACACAGAAAAATTG
+AAATTTGAAAAACTGGTAACGAGACTAGAATCGTCATGATGATCTTGTTG
+AAAAAATTGGAAAAAAATTAAGAATCTAGAAATTGATTAGGCGCAGACTT
+GACACGATCTTGGGCACCGAATCCGCATTTCAGGCCAATTTTCGCATGCT
+CCGCCTTGAGCCCATGACGGGCAGAGGGAGTCATGATCGATGCATCTGAA
+ATGGGGAATATTATTTTTTATTTTAAGCTTCAGGTTTAGGCCTATCGACT
+TTGGATCTCAGGCTCAGGTCCTTAAATTGTGTATCTCAAGCTTAGGCTCT
+CTCGCTCAAGCCTTTAGATTTCAAATCTTAGCCTTAAGCTCTCCGACTGA
+TTTAGGATATCAGACTAAGGGCCTAGGACTTTGGGCCTGAGGCTTAGGCT
+AGTATTCAATCTCAAGCTTAGGATCTCACGCTTAAGCTCTCTGACTCAGG
+CCCTTAGATTGCAAAAACCTTTGCCTTAGGCTCCCCGACTGATTTAGGAT
+ATCAGACTTAGGGCCTAGGACTTCGGGCCTGAAGCTTAGGCTCTCAGATT
+CAGGCCCTCAGACTTTGAGTCTAAGGCCGTTAGACTACGATTTTCAAGCT
+TACAATTAGGCTTTTAGGCTTAAAATCAAAATCCAATTTAGTTTTTTAAA
+AATAATCAAACATTTCTAAACCGCAATTTTTTAAAAATTACCCTAAATAT
+TTCAAATTTTAGGCTTAGACTGTCAGACTTAAACCTTTAAACTTTTGGTC
+TCAAATTTAGCCTACAAGTCTGTGGACCTAAGACTTTGGACCTCGAACTG
+CGGCCCTTAGATCTCATGCTTGGGCTCTAATATCCTGGCCCTCTAGTCCT
+AAATCTTTTGATCGTAGTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCT
+TTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTT
+CAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCA
+GGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGG
+CTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAAGCTTTCAGGGT
+TTCAGGGTTTCAGGCTTTTAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTT
+CAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCA
+GGCTTTCAGGCTTTCAAACTTTCAGGCTTTCAGGCTTTCAGACTTTCAGG
+CTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGGCT
+TTCAGGCTTTCAGGCTTTCAAGCTTTCAGGCTTTCAGGCTTTCAGGCTTT
+CAGGCTTTCAGGCTTTCAGGCTTTCAAACTTTCAGGCTTTCAAACTTTCA
+GGCTTTCAGGCTTTCAGACTTTCAGGCTTTCAGGCTTTCAGGCTTTCAGG
+CTTTCAGACCACAACTAGACCGGCAACACACGTGTTGTCTAATTACTCAC
+CTCTTTGCCGGCGCTCTATGCATATTTGATGGTAACTCGATTGTCTTTGA
+AGCTATCACTTTCACAGCTTCCCAAGTTTCCCGAGCTGTTGGAATGATCT
+GAAACATCAAAAATCATCATCAAAAATCGTGGTGAGACCCAAAATTACCT
+GATTCTCAGCCAGCAAGAATCCATCCCAAACTTGCTCTTCGGGTCTCAAC
+TCGAACAGGAATGAGTACTTGACGTGGGCTTTTCCCTTTGCCCAATCTTC
+TGAGCCACCGGATGCGGGGTCTGGAAATATTTTGAAATTTTATACATAGG
+AGCCTTAAGAAATAAGAGCTTACAAAGTGTATCTGCACCGGTTCCAACTT
+TGTACTGCGTGTTGTAGACACTATTCAAAGCCTGAGCTGCTGAGAGGGCA
+GTGGATCTCTGAAATGTTTAGAAAATATGACCATGACTTGGGCAAACAAT
+TCCCGCATTTTTGTAGATCACACCGTAATGGGATAGCAAAACACGTGGTG
+CCAGAGTGTCGCATTTCGTTTTGATCTACGTAGATCTACAAAAAATGCGG
+GAACTGATTTCTCATGGTTAAGAACGTGCTGACGACAAATTTTTTTGAGC
+GAAAAATTCCCGCATTTTTTTGTAGATCAAACCGTAATGGGACAGCCAGG
+TACCAAGTAAAAAATTTACTCACCAAATCATTCAAATCATTTGAATAAGT
+TCTGACTTGATGGCCGAACGGATACATCAAAATTTGAGAGTACGAGTGGA
+AGGTGAGGAATGTCGAAATACGGTGTCGCTGCACGAAATCTCTAACCGCC
+GCAGTCTCGGGCTCCGAGAAGGCGTAGGCTCCCTGATAGATTTCCGAGCA
+AGGATCAGTTGATGAGCCGACTTGTCCGAAGAACCAGTCAAAGTTTCGAT
+TGAGGTCGACACCTTGACAGCAGGTTGTTGTGGGAGGTTGGAAGAGTCCT
+GAAAGGTTTTTATTTTTGAGATTTTTAACTTTCACGGAGAATTGCCAAAA
+TCTTAGTTTTCATAGCCTGTGTGACATTATTTGGGCGTAACTAAAGTCCA
+GAAAGCTTATGCCTTGTGCTGATGAATTTTTGCAAAAATTGTGCCCAGTT
+TTGCCACTTTTTAGTGGTTTTTGATGGGTTAAACCTAAATTTTCTGAATT
+CAAGTTTTTATTTTTTCCAAATGTTTTTTCAGCCATCGAATGGCTGTCCT
+TTTTTTCGGGCAAAAAAATAATTTTTCTGAAACTATTTGAAACAATTATA
+TTCTAAAAAAAAGGCAATTTTTTAAATTTTTTCTAGTAAATTTTGAGTCC
+TCTAGCTACAAAATAAACCATTTTAGATGAGTTTCAAAAATGTGCATTTC
+TACAAAAATTGCCCAATTTTTGCCACTTTTTGGTGGTTTTTGATGGGTTA
+AACCTAGATTTTCTGAATTCTGCGTATATAAATTACACGTTTTCAACAAA
+TTTAGACATTTTTTTTATTTTTGCCCAATTTTTTTCCAGCCATCTAATGA
+ATATCCTTGTTTTTAAGCAAAAAAAAATTTCTGAAACACAATTATTATGA
+TCCAAAACAGGGGTGTGCGGCAAATCTCAAAATTTGCCGAGCACGGCGAA
+TTTGGCAAACGGCAAATTTGGCAAATTCAGCAAATTTGCTGAGCTTTACA
+AACTCCGCAAAAATTTGATACTTTTTGAAGCACCTAAACTACTAATTTCT
+GAACAAAAGTTCAAAATAACTTGATTTTGTGCCATTTTTCTAAATTTTTG
+GAAATCAATAATTTTGTCAATAATTTTGGTTAAAATTGTATTGTCAAATT
+TTTGACGCGGGCGGCAAATTTCAAAAATTTCTGAGCTCGGCAAACGGCAA
+ATTCGGCAAATTTGTCAAATTTGCCGCACATTTTTTTTTGGTTCAAAACA
+TAATAAAACACTCCAAAACATTTTAGATTTTTCATAATTTCCGGTCGAAG
+TTTTTGCAAATTGCTAAAATTTTGAAAAATATGAGTATTTGAGGAAATCC
+AAAGCAATGCCGCATGTTCCGACCCCTACAATGTTTTAATACAAATGATT
+AAAACAAAATTACAGTAGACAAAATGTAGAAAAAAAATTATTTTTGGTCG
+ACTTCCAAAATTATGAGTGGCAAAAACTTTGTAATTGTCACTTTTTGACA
+GTAAATAAAAAATTTTAAGAATTTTTTTGAAAAGTTTTATTATGATATTC
+GGTCATTTTGGGACCAAATGAGTGGTTTTTAACAATTCCGGCACTGGCGC
+TAGTCCAGCAATTGCCGTAATCTTAGTTTTCATAGCCGACATTATGCGGG
+CCTAACTGAAGCCCAGAAAGCTTGTTTACAAAAATGAGCAAGCAGAAAAA
+GATCAATCTCCCCAACAAACCTGTTGCCTGTTGAATACACTTTGGTGGTG
+ATCGATTCTTTCTCCACAGTCTGATCTCCGGATCATTGCTACTTCTACTG
+TACTCATAACCATCCGGATTCAGCAGTGGAACAATATACCATTCGAGTTG
+ATCTACGAATTGCTTGATTTGAACATCTTTGTCGTACTGGGTGACCAGTT
+GGTGAATGAAATAGAGTACTGTCGATGGTGACACCCATTCACGAGCATGG
+ATTCCTCCGTCCACCCAGATGCCACGTTTCGTACCTCCGTTACGCTTGTT
+GGTGATCTGGAATTGAGGAAAATTGGGGTGAGATGGGATCACTAAATTCT
+GAATCTAGTTTCTGTGCTACTGTGTGTTACGTTTTTTGCGCTCCATTGGC
+AATCGCCTGCCCATCAAAAACCGTCAAAAAGTGGCAAAACTGGGCAATTT
+TTGTAAAAATTCACAATTTTGAAACTCCTCTAAAATGGTTTAGTTCGTAG
+CTAGAGGACTTAAAACTGATTTTTGAACCCTAAAAATTGTCTAAATTTGT
+TGAAAACGGGTAATTCTTGTATGCTGAATTCAGAAAATCTAGGTTTAACC
+CATCAAAAACCATCAAAAAGTGGCAAAAGTGGGCAATTTTTGTAAAAATT
+CACAATTTTGAAACTCCTCTAAAATGGGCAATTTTGTAGCTAGAGGACTC
+AAAATTAACTTCCAAACTCTAAAGAATTGTCCTTTTTCAGAATATAGTGG
+TTTCAATAATTTTCGAACAGAATTTTTTTTGCCCAAAAAAGGATGGCTGA
+AAAAAATTTTGGCCGAAAAAAAAACAGTTTTACACTGAAAGCCAAACCGC
+GACGCGACACGCAAAGCTCGGTAAATCGACCCCAGCCGTGGCCGAGTTCA
+AATAGCCAAATTCGGCAAACTCTCACATTTCAAGCTATGTATTTCAAGCC
+AGAAGCGCGTGCGATTTCTCAAAAACCGGCAGCTCAGTTGCAGGAGGACT
+TTACGAAAATTTTGAAAATTCCAAGGTATAATTGGTAGGTTTTTCGGCAT
+GTTGCATGGTACTTAAAATGTTTTTTTAACTTTCAAAAGTGGCTTTTATT
+TTGGTTCTTATTGCAAGCCTAATAATAAAAATACTATCCACGTTTTAAAT
+GCTTCCATGGTAGGCAGGCGCGGTTTCAGGGCCGACATGGAAGCCCTACA
+TGTCACGGATTTCTGGCTTTCCTCAGAAATTGAAATGGACTAGTTTTTGC
+CGAACTAGGCCAGGCCATATCTGGGGTAGATTTACGGCGCGTTGCATGTC
+GCGTCGCGGCTCGATTTTAGTTGAACAACTAAATGCATTTGTCCGAGTGG
+AGTACACGACTTTCCCACGCGGGCGATTGCCAATGGAGCGCGAAAAATTC
+AATGAGGAGGGCCAGAATCCCGTGATCGTCCGAAGCAAAGTTAAAACAAC
+AAACCTTAATCAACGGGATCTGCCGTCCTTCGTGAGTCGTTCCGATTGGC
+TGCACAGACACAAGCTCCGGATAAGTGATGGCTAATGAGTTCAGGTAGTT
+GATAACATCAGCAAACGAGTGATATTGTGCAAGGTTAAATTGAACCTGCA
+ATAAGTTATCATTGAACTATGTATCATTGAACGTGGTGTCAGAGTGCCTC
+ATTTTGGATTGATCTACGCTGATCTACAAAAAATGCGGGAGAAGAGACTG
+ATTTCGAATGGTTAAAAACGTGCTGACGTCACATTCTTTTGGGCTAAAAA
+TTCCCGCATTTTTTGTAGATCAAACCCTAATGTGACAGCCTGACACCACA
+TGTATTCACTCACTTTCTGCTCCCTCCAATCATGCAGTCGAACTTGTTTC
+CGAAGCTTATCCCGCTTCTCCTTCTGCTCGACAATCACTCTGAAATCGAT
+GAAAAGATTGTAAGTTGGGCTTAATAGTGTCCCCCCACGACACCCATCAC
+GCGTAACGAGCCGTGACGCGTTTGAATAAAGAGGGTATTTGGACTTGTGA
+TCCCCGCGAAAACCTGTATCGCACGTGATGCCAGGGTGTCTCATCACGGG
+TTGATCTACAAAAAATGCGGGAATTTTTTGCCCAAAAATGTGACGTCAGC
+ACGTTCTTAACCATGCCGAATCAGTTCCCGCATTTTTTGTAGATCTACGT
+AGATCAAGCCGAAATGACACACTCTAACACCACGTGGTATCGCCGAAAAA
+CTCACTTCTGAACGTCATCAATCATAACGGAATGCTTAATCGAATGATCA
+TCGAGCTCTTTCATAAACTGCTGAGTTTTCTCATCGGATATCATCACATG
+AACCTCCTTGCCAGCTTCCGACGGGGATTTCCAAAAATCTAGCTGAAAAT
+TTTAGTGTGTCTGAAGCACCCTTATCAGTTCATATTATATTTCAAAATTT
+TTCTCTAACCCCTCAAAACCGTACTCTACATCGCCGTTCTGGCCGAGTGG
+TCTAAGGCGCTGCGTTCAGGTCGCAGTCCTCTCCGGAGGGCGCAGGTTCG
+AATCCTGCGGACGGCAGATTTCTTTTTTGAATACTACTCTTCAAACAATG
+CATGATGAAGAAGAAGAAGAAAAAGAGAAGAACGTATTGGCTTTTCCTTT
+TACACTTTTGAAATCCCTAGGAACAGGTTATAAACAGCGATGTAACATGA
+AAAGCAGCAGTGAGAGTGATCGAAAACGAGCTGATTATGATTTGTTCAAT
+TATATGACACCGCTATTGTAATGGTTGGTTTGTTGCGTGGAACATCATAC
+CTTTACATCGTTTAAATACAAATTATGAAGAATGTCTACTTGATCTTGGG
+TCGTCGGCTGCACCCTCCATACTGTGAATTTTCTGAAAAATCGAGAGTTT
+ACCGGCTTTTGGGGGAGATTTTACCATTGACTTTTGACTTTTTGGAGAGA
+TCTAAATCTAGTAGATCATGCGGCGGTTAGGTCTATTTGAAATAAAAAAT
+AATTGATCTAGATATGAAACATGGAGATCTAAGGGTTTTGGTAAAGTTGA
+GTAGAATTTTTAATTATTTTTTTGAAAATTTGTTTGCAACATTTTACAAA
+AAAAGACGAATAAATATTGACCAAAAAAATTTTTTTCAATAAAAAATGTT
+TAAAAATTAACCACCTTTTAGCTTTTAAAGGTGGAGTAGCGCCAGTGTGG
+ATTTTGTCTAAATACACTTATTATGAACCAAAATGGTCAAATATCATAAT
+AAAACACTTCAAAAAATTTCTTTATTTCAGATTTTTCATAATTTCTGGCC
+AAACTTTTTGCAAATTTCCAAAATTTTGAATGTCGCAGTTTCCGACCCCT
+ACAATGTTTTAATACAAATAATTGAAACAAAATTACAGAATAAAAAATGT
+AGAAAAAAAATTTTTTTTTTGGTCGACTTCCAAAATTATGAGTGGCAAAA
+ACTTTGTAATTGTCACTTTTTGACAGTAAATAAAAAATTTTAAGAATTTT
+TTTGAAAAGTTTTATTATGATATTCGGTCATTTTGGGACCAAATGAGTGG
+TTTTTAACAATTTTCCCACTGGCGCTACTCCCCGTTTAAAGTTCTATGCT
+TTTTAAAACTCACGTTTTTTTTTATGAAGTCTATTTTAAAAAATCTGGAC
+TCTCAGTGGACAGTTCAGCATTTTTCGAAATTTCAGAAATTTAAAACATA
+AGTCGGAAGTGGTCCTAAAACTTCAAAAAAATTCTCACAATATGTTTTTT
+TGATGAAAACAAACTTATATAGTGCCAAAATGACCAAAATTTTTTTAAAA
+ATAATATTGAAAAATCTTTAAAAAATCTCTTCTGGTTTTTATTTATTTTT
+AAAAAATTCATATTGAAATATTATAGTGCTTTAGATTGCTCGGAAAAAAT
+TCCACAAATTTTTTAATTTTTCATAAGTTTTATAATGATATTTGGTCATT
+TTAGCTCTCTCGGGTAATATTGCAAACCCACGTGGTGCCAGGATTTCCCA
+TTAAGGTTTGATCTACAAAAAATGCGGGACTTTTGCTTAAAAAGATGTGA
+CGTCAGCTCATTTTTAACCATGCGAAATCAGTTGAAAACTCTGCCGCATT
+TTTTGTAGATCTACGTAGATCAAACCGAAATGAGACATTCTGACACCGTG
+TCCACCTTCAAAGTTAGTAATTGCATGAACAAAAAATTCTGAGAATGCGT
+ATTGCACAACATATTTGACGCGCAAAATATCTCGTTGCGAAAACTACAGT
+AATTCTTTAAATTACTACTGTAGGTCGATTTGCAGGCTGGATTTTTTGAA
+AAAAAAATGAATTAAAATTTAATGGAATATTTCTATCTCTATGTATTAGA
+AAATAAGGCCCGTAATGAGACGAGCGGGCCTGCCTACCTGCCTGACTATA
+GAAGGCCGCCTTAAAATCAGGCAGGTAGGTTTTAACGCCTAGCCTACAAT
+AAACATAAAGAGAAATGCCTAAAATAACAATAACTTTCCATTATCCTTTC
+TTATCGTCCTCCCCGGCGATCGCCTAAGATCATAGATAACAACTAGCCGC
+TTTCGGTCATGCAATTATTATATTATAATTGATGGATGGATGGGGGATAA
+TCCAGAGAAAGGGGAAAAAGAAACTTAGAATCCTAGAAAACAGGTTCCCC
+TGACTCAAACAAAAAAACCTACTTTTGATGTGCCAACACGGATGGCACGA
+CGAGACCGATGAGGACGATGATGTTCATCATCATCATCTTCATCGTAGTA
+AAACTTGGGGGGTGATGAGGGGCAAAAGGATGCCCTCCGCGCGTCAAGTG
+TTCGTTGAACAATCCGACGCAGACGGTTAAACAAAGCAACACAGTGGTGT
+CTCCGCCCAACTTCCGCGCGTCCGCCGCCGCCCTGTGTACTGTCTTGTCC
+TATCCTATCTCTCTTTTCTCCACCCCGGCTTGTGTGTGAGATTCTTCTCA
+TTACTAGAAGAAGGTCTCTAGTAGAAGAAGAAGAAGAAGAAGAAGACGAC
+GATGGAGAAGAAGCTGAAGGCACGACGCACTGTTTGCGCAACGATGTTTG
+TTTTTGCGCGCGCGAGCGCCGCATTTAAAACGTGTAAATCGGTTTCAAAA
+GCGCGCGCGCGCGGTCTTCTTTCTCCGCTTGCGCGCACGCATTGACAAAA
+AACCGAAAGGTGCAAAAGTGAAGAGGCCAACTACTTTCGTCCTCTTTGAG
+CACCTAATTGTGGAAAGCTTTTGCTCTGATGTGAAATGAAGTTGGGTAAG
+CTATTCCTGTCTGGGTGATGTTTTCAACTTCCGGGGGCATTGTTGGGAAA
+GTGAGGACCAAAATAGGCCATAAAAAATGAAGATATACATGCTTAGGCTT
+AGGCTTAGGCTAGGCTTAGGCTCAGATTCAGGCTTAGGCTTAGGCTTAGG
+CTTAGGCTTGGAATTAGGCTTGGCGTCAGTGGCGAGCGTGAGCTCGCCAC
+TGACGCTATTTAAGCTTGGGTTTATAGCGTTTTTTTAATTTTTCAAAGGG
+TTCCCGTCTGCCGATCAAAGCGAAATTTAACAGAGAGTCGTATAGGCCGC
+CAAGAAGCTGAAGTTTCAAATTGATTTCATTAAAACTCGCTTAGGCTTAG
+GCTTAGGCTTAGGCTTAGGCTTACGTTTTAGCCATATGCTAGCTGATCCG
+GAACATATTTTTAAAAATTGCAATATTTGACCAAAAGCTGTATTTTTCAA
+AAATTCAAAAGTACGGTGAAATCATATGAAGTGCTTCTTTTTCTTTCATT
+AAACTGTTCAGAATTGTCATTTTTACTAGAAAATACCAAAAAAATATGCT
+AGCTTGACCGGAACATATTTTAAAAAATTAGAATTTTTGACCAAAAGCTG
+TTTTTTCAAAAATTGAAAAGTACTGGAAAATCATATGAAGTGCTTCTTTT
+TTCTTTCGTAAAACTGTTCAGAATTGTCATTTATACCAGAATATATTAAA
+CAAAGTATGCTACCTAATCCGGAACATTTGTTTCCAAAATATTTTAAAAA
+AAAGATTTAGCGGCTCTGACTAAATTGTTTGTTCGTTTTTTCTGGACCCT
+TTTTTCCCCTTTTTTTGGGTGAAAAATTTTGTAAAAAATTTGACCGAGGT
+GTAGAGTTGAATTCATCAATTTTTGACATTTTTTGAGTACGGGCACATGA
+AAACGAAATTTCCAAAAACGCTTATTTCTCGGGATATAGTTCAATTCTAC
+CAAATTTTTCTTTGCAAATCTGCTAATTCTACAAATCTACTAACCGAGGT
+GTAGAGTTGAACTCATTTCCAAAAAGAAGTAGCAGTCCTGAAAATGTTTT
+AGTGAGTCTTCTCATTACTCTAGAGCCCGAGCCAGTAAAATTGCTCCAGA
+AGTAGTAATTTATAAATTTTTGATGATTTTATGCTGTCCAATGATAGAGA
+AATTGTTAAAATTTTCAGATCAAATTGGAATTTTCACAGCCAAATATTTT
+GGAAAATTTTCCACAAAAAATTGGGCGGAAAATTGGAATATTAATTCGAT
+TTAATTCGATTTGGAGCAGTGTATAAATTCAAAGTTTCCTCCCTTAACAG
+CCATTCAAATGCACTTTTTTCTTCGTTTAGTTTTTCTTATATATGGCCTC
+CAGGCTCTCACCAAGTTCCGTTTTACCGGAGAGTTTAAGTGCAAACATAA
+ATTCCTGAGATCCCATGTTGTAGTTTATGAAGACGATGAGGTGTTGTGAG
+TAGAAATGAAAAATGAGAAATGTTGTATTTAATATTATAAATTGTTTCAG
+CGACAACGTTATCAGTAAACACCATTACGTGTTCCATACAAATGCACCAC
+ATATGTATCTCGTTGAGGCTGAAGATACCAATGACGGATTGCCAAAGTTT
+TTGGATGTATTACTTTTTAATTTCCCGCTTTTTCTCTAGTATTTCTCAGA
+AAATTTGAATTTCCCGCCAAAATTTTTTATCAGAAAATTTGAATTTCCCA
+CCAAAATTTTTTATCAGAAGATTTGAATTTCCCACCAAAATTTTTTCTCA
+GAAAATTTGAATTTCCCACCAAAATTTTTTCTCAGAAAACTTGAAATTCC
+CGCCAAAAACTTTTTCTCAGAATTTTGAAATTCCCGCTAAAAAATGTTTC
+TCAGAAAATTTGAAATTCCCGCTAAAAAATTTTTCTCAGAAAATTAAAAA
+TCCCCGCCAAAACTTTTTCTCAGAGAATTTGAATTTGCCGCCAAAAAATT
+GTTTTCTCATAAAATCTGAATTTCCCACCAAAATTTTTTCTCAGAAAATT
+TGAAATTCCCGCTAAAAAATTTTTCTCAGAAAATTTGAATTTCCCGCCAA
+AAAATTGTTTTCTCATAAAATCTGAATTTCCCACCAAAATTTTTTCTCAG
+AAAATTTGAAATTCCCGCCAAAAAGTGAACATTCTAGGAGTTTGGCAGTT
+TACCAAAACCTTGACTGACCATTTTGGAAAATCGAATAACCTCTTAAATA
+AAAACTCTAACTTGTAAAAATTTAAAAATTTAAATATATAGCTTTGCAGT
+CCTATTTCGAGTTATACATGATCATCGTCCACGATTGCACGGATAATGGG
+AAATACAAGTTGTTGACAGTTGACTTGGGATCTTATTATATCAAGGATGG
+GTAGGTACTTTCTACAGGGCAGGCTAGGGCTTCCATGGGAAGCAGGAGCG
+GTTTGCCGGCTTCTCGCCTGATTCCTGCACTTTGGCAAAAAGTCAAAGCC
+TCGATGCTCACACATAGGGCTGGCATATTGGACGTCCGGTTTTTTGAAAT
+TTTAAATTTTTCCGAGAGGTAGTTTTTTTTGTACGGCGGCCGACAATTTC
+CGAGTTTGGCCACTCATGATAAAATTATATGATTAAGTATAGTGAGTGGC
+CAAACTCGGAAGTTGTCGGCCGCCGTAAAAAAAACTACCTCTCGGAAAAT
+TTTAACATTTCAAAAAACCGGACGACCGGACGCCCAATATGTCAGCCCTA
+CTCACACCAAATAGTACTATAAGCGGTTTTTTTTGCCGCAGCCGACACTT
+TACGGTTTCCACGCCGCACTGTACAGAAGGCGCGGCCCGAGGCAGTTGTC
+AGGCGTTTTGGCGCCTATATGCAAGCTCTAGGGCAGGCATTTCTGTTTTC
+AAAAAAATGAATATTTTCAGGCAGTACGATGAAACACGCAACATTGATCT
+GAACAATGCCGGTGAATGGACAAACGAAGTAATCGGAACAAAGGCGATGG
+TGATGTCCAAGATATTTATTTTCAATGTTTGATAAAATTGTTCATCAATA
+TTCGAGCCTACCTGCCTACCTGCCTACAAGGTAGCCTACATATATTATTT
+TTCCTAATTAACAAAAATATAATTAAAACATGATTAAGATTTTCTGAAAA
+TGAGCAAAAAGTGTTTTTAACTTCCACTTTTTGCCCAACAGGTTTAAGAT
+AGGCATGTGACAAAGCCTACATTCAAGGCAACCTACGCCTGCCTCGGTAC
+ATGGTGCATCGACCAATATTTACCTCTTAGCTTCGAGAGCTTATATCTCG
+GTTACATTTTGCTCTATCAAAAAATGGCCAACTGAAAAACTGTTCTCCAA
+TGCTTTTTCTACAATTTTGTGGTTAAAATTTTTTTAATATCTTGAAAACT
+AGCGAAAATATAAGCCACCAAGTCGCGCGCCGCCCCCCGAGAAAGCAATT
+CCAACCCAAGTTTATTGCAATAAAAACCAGTAGAAACGAAAGAAATGAGG
+TTGATTTTGGAGACTTTTCAGGTGACACGGGGAGCTTTTACATTGTTGGC
+ATTATTCAGATTCGATTGAGAAGGAGAAGTCGTGGGGAGGCTGAAAAATG
+TTCTAAAGTTGTTGAAAAAAAAAACAAATCTGCATTTTTTAAAAACCTGA
+TTCTTAGACTTCCATCCATTGCCATAAGTGCACAGAACAGTCTGTTGCTC
+TTGCTCTTTGTGCTCCGTGTCCTCGGAGCCATCATCAACCTTGTCTGGAA
+CTGTCGGTGTTGGCTCAGTTGACGGAGCAAATGAGGAGGATGGTGTCGCA
+GATTCTTCAGTTGGTTTGGGAGATGATGGCGGAGCTGGCTGAGGTGGAAT
+TGGAGATGCTCTTTTTTTTGGGGTTACTGCAGACTGTTTGCTCTTCAAAC
+TCTTGCTCCGCGATTTTGTGCTCTTTTTTGTTTTCTTCTTTGGCTGCTTT
+TGTTGCTTCTTGCTTTTTATCTGAAAATTAGAGTTTCTAGGCAATCAAGC
+GATTTTCTAGGCCACCAGACATATATTTAGCCATGTCGGAATTTTCTAGG
+CCATCACAGACAGTTCTAGGCCATATAGAAATTTTCCTAGGCCACCTAAA
+ACTTTTCTAGGCCACCAACAGTTTTCTATGACCGCGATTTTTGCTAGGCC
+ACCAACAAAAGCAAATAACACATTTTCTAGGCCACCAACAGAATTTCAAA
+TTTTTCTAGGCCTTTAACTCACATATTTCACAATGGAAGCGGCGGCGAAC
+ACGATGAAGGCTACAATGAGAATGCCAATAATTATGAATATCACTACTTT
+GGTCCATGGCGTCGATGATGCTGCAAAAATGGAGGTACAAATATGCAAAC
+GCGCTCTACCGCACTACCAGTGCGGTAGAGCGCGTTTCAAACTAACAGCC
+AGAAGTTGGCGCCGGTGGTCGCTGAGTGGAGGTGGACATTATCAGGAAAT
+GAATGAGAAAATGGAGAAATTTGGGAAAATTGATTAGAGACGTGGGATTT
+TTTTTTAATTTTTATAATATTTTTGAGTAGGGGGAAGGGGTGAGGGTCAC
+GGAAAATACCAAAAATTTGTGATTTTTCCATTAAATTGGAGCAAAATTGA
+CACCATACCTCGTGGCCTAGAAAACTGCAGAATTTCTAGGCCACACACGT
+TACGTCATAATTTACCTGTTAAACCAGGTAACCAACAATCAAATCAAGAG
+TAATTAATCATCTCCTATCTTCTTTTATTTCTCCGTTCCTACTCCCAATG
+TTTTTTTTTTGTAATTTGTGATCACAAATTGTTGCATTTTGTAGTACGCC
+ATGTACGTCTGTGTACTACTTTTTTCTGAAAAGAATACAAAAATGTTCGC
+TTTCAGGAAAAAATAGTGAGAGGTAGAAGAAAATTACGGGGACTAGAAAT
+ATGTAAAAGTTCGACAACGTAGGCAGGTAGGCAGGTAGGCAAGTAGGCAG
+TTAGGCAGGTAGGCAGGTAGGTAGGCAGGATAGTAGGCTGCCAGGCATAA
+TAAAGATGCAGGCACGTAGGCGGATGTTGCAGGCATGAGAAGTCACGGGG
+GTAGGCAGGCATGTGGGTATGTAAGCAGATGTAGGTATGTTGCAGTCATG
+ATGAAGGCACGTGGGTAGGTAGGTAACTAGTTAGGCTGGTAGGGAGGTAG
+ACAGGTAGGCAGGCAGGCAGACGCGTAGGAAGAGTTAGCCAGGATGCAGG
+CACGTAGGCAGATGTAGGTATGTTGCAGGCATGCTGAAGTCACGTGGGTA
+GGCAGATTGGTAGATGTGTACGCAGAGTAGGTATGTTGCGGGTATTATGA
+AGGCACGTGAGTAGGTAAGCAGGCAGGTAGGTAGGCAGGCAGGTAGGTAG
+ACATGTAAATATGCAGGCATATACGTAGGGAGAACAAGCCATAATTCAGG
+CACGTAGGCAGATTTAGGTATGTTGTAGGCATGATGACGTAACGTGGGTA
+GGCAGATAGGCAGGTAGGCAGGCTCGTAAGCTGGCAGGCATAATAAAGAC
+ACATAAGCAGGCATGTAAATCTGCAGGCAGATACGTAGGAAGAGCAAGCC
+AGGATGCAGGCACGTAGGCAGATGTAGGTATGTTACAGGCATGATGAAGG
+CACGTGGGTAGGCAGGTAGGTAGGCAGCCAGGCAGGATCGGAGGTTGGTA
+AGCATAAAAAAGACAGGTAGGCGGGTAGGCAAGCATGTAAATGTGCAGGC
+AGATACGTAGAAAGAGCAAGCCAGGATGCAGGCACGTAGGCAGATGTAGG
+CATGTTGCAGGCATGATGAAGGCACGTGAGTAGGTATGCAGGGAGGTAGG
+TAGGCAGGCATGCAGGCACATAGGCAGATGTAGGTATGATTCAGGTAGGC
+AGGCAGGTAGGAAGACTGAATGCAGGCGTGTTGCTAGGCAATAGCGCCCT
+TTCCTTGTTATGACAATCTCGATAATCTAATAATAAGCTATTCAATCATA
+TCACTGCGCCGATACACAAACTACCTGTTTTTTTGAGTATGCGTCTCGTC
+CCGTCTGCCCAAAAGCTTCTACAGAGTGATTAGACGGTATAAGGGGGAGA
+GATAGGATAGATTTCAATCATTCTCACTTTTTTCGTCCCTTTCTCTGTCT
+TCCTTCTCCCTTTTTTTACAGGGCGCTTTTCCCTTTTTCGTGTGTGTGAA
+GAGAGAGAGTGCATACAGGTGTAGAGGACGCCCAGACATCGAGACGGAAC
+AGGATTCTTCATCGTCTTCAGCTATTTGGAAGAAGGAGTAGAAGGTGACG
+GTGTGTGTTTGGAGACGTGTAATCATCATGTCTTATAACACTTCCTTGCT
+CATTTTTCTCTGCTTCTCTGCCGTCTCTCTATCCACACAGTCTTTCGCCG
+TTTATCGATTATTACCCAAATCACAGACGGATTTTCAAGCTATACAGAGG
+TTATACAAAAATGCGACGGATCATGATGTGAGTTTTGTTTTCGCATTTTT
+GAGCAGATACAATTTCTAGGCCACGAAAAATTTTTCTAGGCCGTTGAAAA
+AATCACTAAGTTTTCTAGGTCACAATTTTGAGCAAGTTCTAGGTTATTAG
+ATTATTACGCCATGGTGCATTTTTCTAGGCCATCAGGAAATTTTGCAGGC
+CACCATGAGTTTTTGATGCAGTTGAACTAAGTTAGTGGCCTAGAAAAACC
+TTTGTTAGCCTAGAAATATTTTCGCCGGCCTAAACACATTTTTGGTGGCC
+TAGAAACACTAACTTTTGGTAGCCTAAAAATTTTCTGTGACCTGGAAACA
+TTGTTGGTGGCCTGAAAACATTTTTGGAGGCTTAGAAATATTCTTGGCAA
+TTTGAAAACATTTTTGGTGGCCTAGAAATATTTCTGATGGCCTAGAATGT
+TTTTGTGGTCTATAAATAATTTTGGCGGCCTAAAAAAATTTGGAATGGCT
+TAGCAAAATTTTTTTGGTGGTCTACAGCCATTTTTAACGACCAAGAAACA
+TTTTTGGTGGCCTGAAAACATTTTTGGTGGCCTAGAAACATTCTTGGTGG
+CCTGAAAAAACATTTTCGGTGGCCTAGAACCATTTTTGGAGACCTGGAAA
+TGTTTTGGTGGCCTAGAATATTTTTGGTGGCCTAGAATATTTTTGTTGGT
+CTAGAAATATTTCTGATGGTCTAGAATGTTTTTGTGGTCTATAAATAATT
+TTGGTGGCCTAGAAATATTCTTGGAGACCTGATAACATTTTTGGTGACCT
+ATAAATATTTTTGACAGCCTAAAAATTTTCGGTGGCCTAGAAATATTTCT
+GATGGCCTATAATGTTTTTGTGGTCTATAAATATTTTTAATGACCTAGAA
+ACATTTTTGGTGGCCTTGAAACATTCTTGGTGGCCTAGAAATGTTTTTGG
+TTTCCTAGAAACATTCTTGGAGACCTGAAAACATTTTTGGTGGCCTAGAG
+ACATTTTTAATGGCCTAGACACATTTTTGGTGGCCTAGAAATGTTGCTGA
+TGGCCTATAATGTTTTTGTGGTCTATAAGTATTTTCGGTGGCCTAAAATA
+TTTTTGGTGACCTAAAACATTTTTGGAGACCTGGAAATGTTTTGATGGCC
+TAGAAATATTTGTGCTGTGCTGAAACATTGTCGGTGGCCTAGAAATATTC
+TTGGAGACCTGAAAACATTTTTGGTGGCCTAGAAAAATTTTTAGTGACCT
+AAAAACTTTGGGAATTACCTGGAACCAATTTTGGCGACCTAGAAAAATTT
+TCCGTGGCCTAAAAATTCCCAATAATTAACAAATTTTTAGTTAAACTTCT
+GGAAAACGGGCAAGGACAAGCACGGGTTTTGGGATGTGATGGTGGATATG
+AAGAATTCGAAATATTTTTTGGACTTTCTACAAGTAAATGATATTTCTTA
+CATAAAGACGATTGATGACGTGGAGGGGTGAGCTTTTTCTGAAATTTTGA
+AAATTACATAAAGAATATGTGCTCTATTGATAAACTGTTAGGATCACCGT
+AAATCGACAAGAATCTCCGTAAATCCACAACGGCCCCATCTCAAAAATTC
+CTAGGCCACACGTGTGACGTCATTTTTCTTCCAGATTAATAACAAAGCAC
+GAGAACAACAAGACCCTCTCGAACATGTTCCCCCGTCTGTGGGATGACTC
+CTCGTCTGCTCACTATGACTTCCACACCTATGGATCCTATCAGCGAATGA
+CTGATTGGATGAAGCAGCTGGTGGTGAAGTATCCAAAGATGGTTCAGTAT
+ATATCGATTGGAAAAACTACGGAGGGCAGGAATATCGATGGAGTTGAGGT
+AGGTCTAGAAGGCTGCCTTAGGTCTAGGTCTAAGTCTAGGTTTAGGTCTA
+GGTCTAAGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGG
+TCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTC
+TAGGTCTAGGTCTAGGTCTAGGTTTAGGTCTAGGTCTAGGTCTAGGTCTA
+GGTCTAGGTCTAGGTCTAGGTCTAGGTCTATGTCTAGGTCTAGGTCTAGG
+TCTAGGTCTAGGTCTAGGTCTAGGTCTAGATCTAGGTCTAGGTCTAGGTC
+TAGGTCTAGGTCTAGGTCTATGTCTAGGTCTAGGTCTAGGTCTAGGTCTA
+GGTCTAGGCCGATTTCGATTTCTATGTGTATGGCCTATAGTGATTTTCAG
+ATCGGCGGAGACTCCCGCACCAAAAAGATTTTCTGGATCGATGGAGGTAT
+TCATGCTCGAGAATGGGCGGCCCCGCACACGGCTCTCTTTTTCATCCATC
+AGGTATGTGATCCCGCCCCGTCAGAAAAAAGTGTGTTCCGATTAGTTCCG
+CTTGGATTACACAAATGTTGGCAGAGACAGAAAAAGGGAAAACTTGATAA
+CAAATGGGTTGGAAAAAACGTAATCGGATGATGCAATCGCGCTCTATTGC
+ACTACCTCAACAAAACATTTTTTTGCAGCTTACCTCCCGCGCAAACGAGC
+CCGGAATCAAGAAATTGCTGAACGAGATCACATTTGTAGTGGTTCCCTGC
+TTGAATCCAGATGGCTATGAGTTCACGAGATCCTCCACAAATCCACATGT
+AGGTTGGGGTAAGGTTACTGTACCCCCCCCCCCCCCCCTCCCCAACTCAA
+AGGCGCAAGCACTCCCAAATTTTTTGCAGGTTCGTCTGTGGCGTAAGAAT
+CGCTCGAAAATGCAATGCCGTAAGGACATTTGGGGACGCAATCGCTGCTG
+TCGCGGTGTCGATTTGAATCGTAATTTCGATTTCCACTTCAGAGGTGAGA
+GAGAGAGGGTGAAGTGGTTTTTCTCAAAGTGGACTTGAAAATTAAGGGTC
+AAAGTTTTAAAAGAAAACTTTGAAAAAAACTTGGGAATTTGTTCACGAAT
+ATACGAAGTTGCTGAAAATTTGTAAAACGTTTTGGAACATTCTAAAACTA
+TTTGAATTTAAATAATTTTTTAAACATACCAAAAAATCATGGATGTTCTC
+AAAATTCACGAAAGTTTCGAAAATTCCCTACAGTACTCCTGAACTAGCCC
+TACAGTATCCTTAAAGTACCCTACAGTACCTATACAGAACTCCTGTAGTA
+CCCTTACAGTATCCCTAAAGTATCCCTACAGTACCCCTACAGTTTCCCTA
+TAGTACCCCTACAGTACTCTCGCAGTATCCATACAGTAGCCCTACAGTAT
+CCCTACAGTACCCCTACAGTATTCCTACAGTACCCCTACAGTAGCCCTAC
+AGTACCCCAGTAGCACCCTTACAGCATCCCTAAATTATCCCTAAATTATC
+CCTACAGTACCCCTACAGTACCCCTACAGTACCCCTACAGCATCTCCATA
+GTACCCCTATAGTAGCCCTACAGTATCCCTACAGTTCCCACACAGCCCTT
+ATAGTGCCTATACAGAACCCCTATAATACCCCATACAATACACCTACAGT
+ACCCCTACAGTATCCGTAAATTACCCCTATAGTACCCCTACAGTACCCTG
+ACGGTACTCCTACAGCACCCCTACAGGACCCCTATAACATCCCTACAGTA
+CCCCTGCAGTACCCATACGGTTTCCTTACAGTATCCCGTGAGTATCCCAA
+CAATACTCTCACAGTACTGCTACAGTACCCCAAAAGTACCCCTACAAAAC
+CCCTACAGTACCCCTACAGAACCCTCACGGTACCCTACCGTATCCCTACA
+GTACCTGAAGCTCCAAAAATTTCCCCCACTTCCAGAAAGCGGTACAAGCG
+ACGACCCGTGCTCCGAGATCTACCAGGGACCCTCTCCATTCAGTGAGCCC
+GAGGCAAAAGCCGTACGGGACGCGTTGTTGTCGCAGAGATATAAGGGAAG
+AACCGACGCCTATATCACACTACACACTTATTCACAGGTACTGTTAAGCA
+GTTGAAAACTTTTTCTCGGCCACCGATATTTTCTCGGCCATCGATATTTT
+CTCGGCCATCGTTATTTTCTCGGCCACCGAAATTTTTCGCGGTCATCGAT
+ATACTCTCGTTCACGGATATTTTTCCCAGCAACAGATTTTTTTCTCGGTC
+ACCGATATTCTCTCGGCCACCAAAATTTTGTTTTTCGTGGCCATCTATAT
+TTTCATCGGCCATCTATATTTTCTAGGCCACCAATTTTTTCTCGGTCTCC
+GATACTTTCTCGGCTACCAACTTTTTCTCGGCCACCAACTTTTTCTCGGC
+CACAGATTTTTTTCTCGGCCATTAATTTTTGACGGCCACCGAAATTTTTT
+CGGTCACCGATATTTTTCACGGCCATCGATATTTTTTGAAAATTTGATTT
+GAGCAAAATATTTTCAGATTTGGATTCATCCATATGGTCACAAGAAGGAT
+GCATATCCAGGAGATATTAAGGATTTGGTGAGTGATGACGTCATTCTTCT
+TGAAACGTTGAAACTCAAATTTCCAGTACGAAGTTGGCAAAAAAGCTGCT
+CAGGCTCTGAAACGGGTTTACGGCACAAAATACGTAGTCGGAAGCGGTGC
+GGACACGCTCTACCCGGCGTCTGGAGGATCTGAAGATTGGGCAAAGCACG
+AGGCGAAGGTCAAATTTGTGTACCTTCTAGAATTGAGGCCCGACGAGAAA
+AGTAAAAAAAAAACGTTCAAAGTTGCTGAAAAAAGTTGGGCGATAATTTC
+AGACTGGGATGGGTTCATACTGGACGAGAAGGAGCTGATCCCGACGGCTC
+GGGAAACTTGGGAAGGTGTCCGAGTTGTGGCGGAAGCTGTGCTCGATCGG
+ATAGTTGCCGGCAAGTCGACGGCTCCAAGAGGTAGGCAAACTTTGATGTG
+CCTGCCTGCCTTGTGCCTACAGTTTTATTACGAGTAGGCACGGAGGTAGG
+CAAGTAGGCAGGCAGAAATGTGGACCGATAGGCGTAAGGTTAAGGGCTTG
+CGAAGCTTTTGCGTAGGATTGCGAAGAAAAAGAAAAATTTTTAAATTACA
+GTGCGCACGGCCTAAAGGAGATGGCTTCTGAGGTAGTCACTACGATGCTC
+CGCTTGCTCTGACCACGCCCCTTTCCTGGTTTCTCGATTTTTGTTTTAGA
+AATTACACTTGTTTATTTTATGATTGTTGATAAATGTTTTTTTAAACATA
+ATTTTTCTTGAAAAAACAACTTACAATTAGAGAAAATAGCAGCGAGCGGT
+CGTGGCCGCGAAATGAAAAACTCGGCCACCAGCTATAAAATTAAAACGTA
+TAATAATTTGGTGGTTCAGTTTTGCAGAAAAAAAATGGCTGGCCGAGTTT
+TCACGTTTCTAGGCCATCTAGCAAAGTTGCTCTGAAGCGCTTTCGCGAAT
+TCGTTTCCGAAAAAACTGTAGGTGAAAACTCGACCACGCTTTCTTAAAGC
+CACGAAATTTTGAAATAATTTCTCGGTCACCAATTTTTTCTCGGCCACCG
+ATATTTTCTCGGCCACCGATATTTTCTCGGCCATCAAAATTTTTCTAGGC
+CACCAACTTTTTCTCGGCCATCTATATTTTCCCGGCCTCCGACATTTTTT
+CTCGGCCACCGATATTTTTCGCAGCCGTCTATATTTTCTTGGCTACCAAT
+TTTTTCTCGGTCTCCGATACTTTCTCGGCTACCAACTTTTTCTCGGTCAT
+AGATATTTTTCGCAGTCATCTATATTTTCTCGGTCAGCGATATTTTCTTG
+ACAACCCATGTTTTTCTCGGCCACCGATATTTTTCTCGACCATCTATATT
+TTCTCGGCCACCAAAATTCATTCTCGGCCACTTATATTTTTCTCGGCCAC
+CAATATTTTTCTCGGCCACCTATATTTTCTCGGCCACAGATTTTTTTCTC
+GGCCATTAATTTTTGACGGCCACCGACATTTTTTTCGGTCACCGATTTTT
+TCTCCGCCATCTATATTATCTCGGTCACCAATTTTTTTCGGTCATTGATA
+TTTTCTCGGCCACCAATATTCTTCTCAGCCATCAATATTTTATCGTCCAC
+CGATATTTTATCGGCCACCGAAATTTTTCGCGGTCATCGATATACTCTCG
+TTCACGGATATTTTTCCCAGCAACAGATTTTTTTCTCGGTCACCGATATT
+CTCTCGGCCACCAAAATTTTTCTCGGCCACCGATTTTTTTTCCTGGCCAC
+AGATATTTTTCTCGGCCTCCGATATTTTTCTCGGCCACCGATATTTTTTC
+TCGGCCACCAATTTTTTTCTCGGCCTCCGAAGTTTTTCGTGGCCATCTAT
+ATTTTCATCGGCCATCTATATTTTCTAGGCCACCAATTTTTTCTCGGTCT
+CCGATACTTTCTCGGCTACCAACTTTTTCTCGGCCACCAACTTTTTCTCG
+GCCACAGATTTTTTTCTCGGCCATTAATTTTTGACGGCCACCGAAATTTT
+TTCGGTCACCGATATTTTTCACGGCCATTGATATTTTTTTCGGTCACCGA
+TACTTTCTCGGCCACAAATATTTTCTCGGCCACCGAAATTTTTCGCGGTC
+ATCTATATTTTCTCGGCCTCAGCCATCGATATTTTTCTGGACCGTCTAGT
+TTTTTTTTGGCGGCCGTGACCTCCAAATAGAATTACAAAAATAAACGATA
+CATCTCATATTTCTGTGCAAATCCTCAAGTACCCCCCCCCCCCCCCCTAT
+ATTTATTGTTCCAGAAGCCCCAAAAGCTCGCGGATTCCGATTCGGCGACG
+GCACCGAAGGATCATGTTTCGATGTCCGACACGCGTGCAAACGATGGGTT
+CAGGAACGGGAGGAGCTGTGCAGGACGGTGCCAATTTTCATGCGCGAGAA
+CTGTGCCTACTCTTGCAATTTCTGTTGATTTTTTTGGTGTGCCACTTCTT
+TTTTTCTGTACATATATCCATTTTGTCTTCTACATACATATATATATGTA
+TATGAAATGTTTAAAAACCTAAAACCTAAAAAAAAACCAACCTAATACAG
+TGTTCACGAGCGCCCCCCGCCGCCGGCGGCTCCTTATTTGCCTTGTGCTC
+ACCGTGAGGTGGCTCCGCGCGGGAGCCCCAGTGATGAGCATCTCTTTTGT
+CCACACGAATAATACAATAACACGGGCTCCTCTTCAAATATGACAAAATG
+TCAAATTTTGGCGTCTCTCCTGACTTGGAGCTTCTGGGTCTTCAGACACG
+TTCTTGTGTGTGAGGCGAGATGCGATTACCCTCTATATTATTGATTTTTG
+GAGCATTTTTTGGTTTTCTAGGGGCTATTCATAATACAGATGATAATGCC
+GGCTATCATAAGTAAGTCCCCAAAATACCCATATGGCCTAGAAATTCGGA
+AAACTCTTCCATTTCACTTTTGGTAGGGACATTTGGTTTCTGTGCTAGCT
+TTTATGCTGAACATGGTAATTTAAATTTCCTAGGCCAGTGTATATGTTTT
+TCTAGGCTACGACATACAATTTTTTAGGCCACAAAATATTTTTTTTTAAT
+TGCGGCTTATAAAAATGTTCCATAAATTATCTATTTTTGAATTACAGTCT
+GAAAATTTCCATTTTTCAAGGGCACCTTTCTAGGTCACAAAAACGGATTT
+TTTCAACATAGGCATTTTTCAACTTTTTCTAGGCCACGACAGATGGAAGA
+GCTTTTCGTAAAAAAAGCTCGGCCACCACCCCACCTAACCAAAAAACTTC
+CAGCTTCAAACTAATCCGAATCAATCCGGAAACTGAAGGAAGTGTGAAAT
+ATCTTCGAAGTCTGTACGAGGATCCCTCTCCGTACGAGCTGGATTTCTGG
+CAGCCTCCTACGAATATCGGTTAGTGTGACTTACCCACGTGATGTTAGCG
+TGCTCCATTTTAGTTTGATCTACGTAGATCTACCAAAAATGCGGGAGAAG
+AGACGCAAAGTTCTCAACTGATTCTGCATGGTTAAGAACGCACTGACGTC
+ACATTTTTTGGGAAAAAAATTTCCGCATTTTTTGTAGATCAAACCGTGAT
+GGGACAGTTTGCCACCACGTGCTTACCCAGGAAAATCTGAAATTTTTCGA
+ATTTTCAGGAGCTATCGTAGACTTGACAGTTGCTCCGGCGGATGCTCCAA
+GATTTGTGAAGGATTTGGAATCGAAGAAGATCAGCTACATCGTGGCGGTT
+AATGATTTGTCAAAGTTCGTTTTTTTTTCTAGGCCACGGCCATCTGTGAC
+GTCACTAAACTAGTTTCCAGAGCAATCGAAAACGAGCGCGGAAGCGACAA
+ATTCTACAACCCGGTCGCTGGTTTTGCATACGACAAGTACAACAGTTTGG
+AGGAGATTCAAACAGAAATGAAGCGGCTTAAGAAGGAATACCCGACCATG
+ATCACGCTTATCGATATCGGACAAAGTCACGAGAATCGTACGCTTTTGGT
+GATGAAGGTAAGAGCGAACGCGCTCTATTGAGTGGGCGTGGTCACGTCCA
+CGTTTTGCAAAGTGGGCGCACGGTTCCTTTACAGCGGTCCCAGCTTTTGA
+AGTTTTGAGTAATTTTTATATGGGAATTGCTAAAATTCATTTAAAAAAAA
+CCCAAAAATACTTTTAAAGTCGTAACGAAAAAAAACAACCGTGCGCACGT
+CTTGCAAAAAGTGGGCGTCCCAAAATTTAAAAACGACGGAATTTCATTAT
+TTCAAACGCTCCAAACTCATTTTCACTACAAAGACATCACGCGCCTCCTG
+GGAAAGCCCTTACTCATTTGCTGGATATATGACGTCACTAAATTAGTAGA
+TGTGTGAAACCGCGCTCCATTGTACTACGCAACACCGATCCCACGTGGTG
+TCAAAGTGTCCCATTTCGGTGTGATCTACCATAAATGCGGAAATATTGAC
+GCGGATTTCTAAACAGATTTCGCATGGTTAAGAGCGTGCTGACGTCACAA
+ACTTTTCTCTGCAAGAAATTCCCACATTTTTTGTAGATCACACTAAAATG
+GGACCGTTTGACGCCACCTGCGCTCTCACTTTCAACACTCCCATTAAGCA
+TTTCATGTACGCGCCAAAACGCACGGATTTCTGGCTCCCCTCATAAATTG
+AAATGGAGTTTGAAAAAGAGTTTGCCGAACTAGGTCATTTTGGCTCGGCC
+ATATTTGGGGTAGATTTTCGCCGCGTTGCGTGTCGCGTCGCGGCTCAATT
+TAAGTTGTAAATCTAAATGTGTTTGTCCGTGTGGAGTACCCGACTTTTCC
+ACGCGTTGCCCGGAATGCTATTGTCGATGGAGCGCGAAAAATTCAATAAG
+GAAGGCCAGAACCCCGTGAAAACGCCTGCCGCGCCCCCGCCTGCCTTGCA
+GCGCGGAACCCAAAAAGTGTCGGCCGCGGCGAAAGGCCCTCGCACTATGT
+GGTGTTAATACCTAGCTATTGACTTATCGCCATAGTGTAAAAAAACCCAA
+ACTCCCAAATTTTCAGATAACCGGAAAACGAAACCCCCTCGGCTCGAAAA
+TCTCCATGTGGATTGACGCTGGAATTCATGCTCGAGAATGGATTGCTCCG
+GCGACCGCAATGTACATTGCTCATGAGCTTCTCCTCGGGTATGAAAACGA
+CGCGACGGTGGCTAAGCTGATGGACCATATCGATTTTTATATTCTACCTG
+TGATGAATCCAGATGGATATGAGTATTCCAGAGAAAAGGTTGGTTTTTGA
+ACCTTAAAAAAGCCTTAAAACTAGTGCTCTATTTCAGAACCGCATGTGGA
+GGAAAAACCGGAGCCCCGCAAAATGCGCCCGGCAAACTTTCAGTACGGTC
+TGCTGCTCTGGAGTCGACCTCAACAGGAACTTCGATTGGTTCTGGGCCTG
+TAAGTCACGTGGTGTGAGAAAGTCTCATTGAAGTTTGATCTACAAAAAAT
+GCGGGAATTTTTTGTAGATCAAAGCGAACTGGGACTTTCTGACTCTACGT
+AGTTAGCTCAATATTAGACCTTAAAAAATAACTTAATCTTAAAAATTTCC
+AGCCACCGGTTCGTCTTCGGATCCGTGCCACGACACGTATCACGGCTCGG
+CGGCCTTCTCGGAGCCTGAATCACAAGCTGTCAGGGATTTCCTGGAGCAA
+AACACACCCGAGGCGTTCATCTCGCTGCATTCCTACTCCCAAATGTGGTT
+GATACCATATGGACACAGAAAACAGAGTTATCCACAGGACTACCATACTG
+GACTGCGGCCATTGGCTCTGCGAGCAACTAAGGCGTTGTATGAGTTGTAT
+GGGACGAAATATCAAGTCGGGACCGGCGCTGATTTGATGTGTAAGTTAAT
+ATCCTTTTTTTCGAATTTTTAAATTTCTAAGGATTTCAAGAAATTTTAAA
+ATTTTGAAAATTAAAAAAACAATTTTTTTCGGAATGTTTAAAAATTAAAA
+AAAAAATTTTTTTAATAGATTTTTTAAAGCTTTTTTTTGGAAAATTTTGG
+ATTTCTGAATAATTTTTTTTTCAGAACTGGAATTTTTGAGTTTATTAAAG
+ATTTTTTTAGGACTTTTTAATTTAGACATTTCCTGAAAAATTTTTAAATT
+ATTAAAATTTCGAACTTTTTCGATATTTTCGGATTTTTTTGCAACCTGAA
+TTTTATTTTTTTTTTGGATTTATTGGAATCAGGGGTGGGCAGCAAGATTT
+TTTCCGGCAAATCGGCAAATCGGCAATTTGCCGGAATTGAAAATTTCCGC
+CAAATCGACAATTGCCGGAATTGAAAATTTCTGGCAAAACGGCAAATCGG
+CAAACTGCCGGAATTGAAAATTTCTGGCAAACCGGCAAACAGGCTAATTG
+CCGATTTGCCGAATTTATCGATAAATCAGTTTGCCAAACGGCAATTTCCC
+CCACCCCTGATTGGGATCTTTGAAATAAAACAGGAAGAAATTTTAAATTG
+TTGGAAATTTTGTAATTTTCCGGAATTTTAATAAAAAAATGCTGAAAATT
+CTAAAAGTTTTGGAACTATGTAAAATTATTTGTGATTTAAAAAAAAACAT
+TTTTTGGACTTTTCTGAAATTTCACGGATTTCTGGCTTCTCTCATAAATT
+GAAATGGAAGAGTTTTTGCCGAACTTGGCCATTTTGGCTCTGCCATATCT
+GGGATGGATTTACGGCGCGCTTCATGTCGCGTCGCGGCTCGTAAAACTAA
+ATGCACTTGTCCGTGTGGAGTGAGGAGAAAATTCAATGAGGAAGGCCAGA
+ACCCCGGATTTTTGAAATTTTGAAGTTCTGAGAAACCTGTGACTTCTACA
+CTAACCCTGAAGAATTTCAGACGAAGCTTCTGGAGGATCACATGATTGGG
+CTAAGGGGCAGCTTAAGGTCCCCTATGCCTACCTGATTGAGCTCCGACCA
+AAGAACACCATGATGGGGTAAGCAGGACGATGGATCCTATCAAAATTAAA
+ATTTCATTCCAGCCACGGCTTCCTTCTCCCCGAACGAGAAATTGTGCCCA
+CTGGACTGGAAACCTTCGAATCCATCAAAGTGGTTGCCGACGAGCTTGTG
+GCGCAATTTGTGGAACCTGTGATTCGAGCCAAGCTGACCACAACCACAAA
+GCCCGCAATCCCACCGTATCGGCGTGGGTACTCTATAATCGACACCACAA
+CTATGGAGCCGGTCGATGAGATTACACAGAAGCCTACAGAAGCTCCAACC
+ACAGAGGAGCCCACCACCACTACTACGGAGGAACCTACAACTACCACAAC
+GACCGAGGAGCCTACCGAAGCCCCAACAGAACCCAGTCCGACTACTGTCG
+AGGCCACCGAGGCTTCTACAACACCAGAAGCTTCCACATCCTCTGAGACA
+AGTACCACAGAGAATTCTGAACCCAACCAGAAGACATCCACACCAGTGGC
+ACCTGAAGCAAGCACCGTTGAGGAGGTTGGTTTTTGGCTTAGTCTCAGGC
+TTAGGCCTAGGCTTAGGCTTAAACTTAGCCTTAGTCTTAGACTGAGGTTT
+AGGCTTAAGCTTAGGCTTCAGCTTAGGCTTAAACTTAGTTTTATCTTAGG
+CTGTGGCTTAGTCTTAGACTTAGTTTTAGGCTTAAGCTTAGGCTCAGACT
+TCGGCTTAGGCTTAGGCTTAGAATTAGGCTTAGTTTTAGGCTTAGACTTA
+GTCTTGGGCTTAAGCTTCGGCTTAGGCTTAGTCTTAAGCTTAGGCTTAGG
+CTTGCACTTGGGCTTGGCGTCAGTGGCGAGCGTGAGCTATTTAGGGTTTT
+ATGCTTAGCTTTAGACTTAGGCTGAGGTTTAGGCTTAGGCTTCGGCTTAA
+GCTTAGGCTTATGCTTAAGCTTAGGCTTGGACTTAGGCTCATACTTAGGC
+TTAGGCTTAGGCTTGCACTTGGGCTTAGGCTTAGGCTTATGCTTAGTTTT
+AGGCTTAGATTTAGGTTCAGGCTTAGGCTTATACCTAAGCAAATACATTT
+TTGGAACTATTTGGATATTTGCCAGCGACCTATTTTATCAACTTCGAATT
+TCCCAAACCATTCCAGGAAACAATCACACCGATCAAATGCGTCGACTACG
+GTGACTACTGTCGTCTTTGGGGAGTCTTACAGCTCTGCTATCGGGATCAG
+GTCTCCAAGTTGTGCCCCAAGACTTGCGACTCGAGGTGCTCTTTTTCGGT
+GTGAGGCGCACGCTGGAAACTATCGTATGACAAATTGTCAGCTTATGTAT
+GTATAAATGATTTCAAACTTTTGTAATTGTGGACTAAAAACTACATTTTT
+CATGCCTGACTGACTGCCTGGCAGCGTGTCAGCGCCCGACATTTTCTGAG
+TTCCACGACGGGATCCTGGCAGGCGTAGGCGTGCAATTTTTAACTCATCA
+AATTGCTTGGAATAATTAAGCACTGCTACAAATGATGTCACTAGCTACAA
+ACTACAAACTAGGAATTTCACACTACAAACTACAAACTACAATCTTAGCT
+CTTCAAGCTATGAAATACAAACTAAGAAATTTTTATTTTTCAATATTTTT
+TAAACGAGGTGTAATTATGGGCGTATATAGTAAAAACTGGAACGACAAAA
+TGCAAATCACAAACTACAAACTAGAAACTAAAAACTAGAAACTGCAAACC
+ACAAACTACAAACCACAAACTACAAACTACAAACTACAAACTACAAATTA
+CAAACTACAAGCTACAAACTACTGAACTCTGAATAAATTTGAACGTGTAA
+ATTTTGCGTTTTTGTGCAATGATTGGACGTATGAATTGCGAAACCATAAG
+TGTTTAATCACATACTACAAACTACAAACTACAAACTACAAACTACAACC
+TAGAAACTACAAACTACAAACTACAAAATATAAATTACAACCTTCAAGAA
+ATTTGTATTTTTCAATATTTGTCGAACAAGTTTTAATTATTCGACGAATA
+AAGTCAAAGCTGAAATCATAAAATGCTAACCACAAACTACAAACTACAAA
+CTACAAACGGCAAACTACAAGCTACAAATTACTGAACTCTAATAAAATTT
+GAAAGTGTACTCATGGTTTTGTGCAATTACTGGACGTATGAATTACGAAA
+CCATAAGTTTTTAGTCACACACTACAAACTATAAATTACAAACTACAAAC
+TACAAATGAAAACTACAAACTACAAACTGGAAACTACAACAGCAAACTAC
+AAACTACAAACTACAAGCTACAAACGCTTATATAATTCGATTTTAGTTAT
+TTTCTGTTTTTTATTTTTCCAAATTCTCAAACCTGAAATAAAATTACCTA
+CACACAAATGTTTCTCATTATGCATCGAATGACTAATATTTTCCAATAAA
+CGTTTTGAAAAAGTATGGAAGAAACAAAAAATGGAAAACAAAGGCGGAAA
+TATGCATTTTTCTTCTCATTTTCTTGAAATTCGTGTGATTGTACTTATTG
+ATTTTTTGTTGTTGTTAAAAACGTGGTAGGCAGGCATTCATGCCTACGTG
+CCTGCCTACCAGTCGAATTCGAACCCGCAAGATGTCGGCCGCTCCCTTCG
+ATTTTGGAAGTTTTTACTTATTTTCCTCTTCTGCTAACACATTAGACAAT
+TATTATTCAACCCGTGTACACAATAGGGCGGCTAATAATTAGGTTGGCAG
+GTAGAGGTGTACAGGAAACGTTTATAAGCTCTTTATTTACTACTGAGCTA
+CCACTTATTTGGAGCCAATGCATTTTGTTTCTCAACAAGTTGGAGATTCC
+AGAACAACCAAGATTTGGGCGGGGCTTATTTTGAGGCAATTTTTCAACTG
+TACAGTAGATTCATATAATTTAAGTTTTGAAAACATTTAGGCGGGAATTC
+AAACATTTATTTTTAAAACCATCTTGGCGGGAATTCAAATTCTAGTTTTT
+CGAAAACACTTTGGCGGGAATTCAAAATGTTATTTCTTAACAACTTCCTG
+AAATGCTCTAGAACCTTCTGGAATATTTGAGAAAACTCTAGAATGTTCTA
+GAACCTTCTGAAAAATTCGAAAAAAGTCTAGAATGTTCTAGAGCCTTTTG
+GAAAATTCGAAAAAAATCTGGAATATTCTAGAACCTTTTGGAAATTTTGA
+GAAAATTCTGGAATGTTTTGGAACCTTCTGGAAAATTCGAGAAAATTCTG
+GAATGTTCTAGAACCTTCTGAAAAATTTGAGAAAATTCTGGAATGTTCTA
+GACCCTTCTGGAAATCCGAGAAAATTCTGGAATGTTCTGGAACCTTCTGG
+GAAATTTTTAGAAAAATCCTGGAATTCTCTAGGACCTTCTGGAAAATTTG
+AGAAAATTCTTGTCGCCAAAGTTTTGTGAAAAAATTTAGCTGGAAACTAA
+ATAATTTTGTGAGAATTCAAACTTTAATTTTTCCAATTTTTTCGGATTTT
+TTTTTTAGCTTTTAAGCTTTTTACATTTTCTATAAATTTTAGATTTCAAA
+AAAAAATTGGCGAAAAATTTTGACCAAATTTTTTGGCTTTATAGCATAAT
+TTCAAAAAGTTTAAAAAGTCCAAACTTTGCTCCAGTCCCCAAAAAAAAAT
+TTGGTGGAAAATTCAAATCATGTTTTTTTTTCAAAAAATTTCATGGCCTA
+GAAATTTCAGCAAAGCAGTAAGGCCGCCTACCTCCCTTCAATCCGAAAAA
+TACCTAAAAATCAATCCCAAGCAATTAGTCTCATCAAGAAAGAAAAGAGC
+TCTGCTTGTGCCCACTCCTCATCTCTTCTCATGTATTTGCTTTCAATTAA
+ACATCTTACTCAGACAGCATAACGAAGGAAACAAAAAACGAAAGAATAAC
+GAAATGAGCATATTTCCTTTATTTATTCCTTATTTATGTATTCAGGTAGA
+ACAAAAAACCGGCTCGGCGGGTTTATTTGTCTGTAAATCTTATGCCTACA
+CGCCTACCTACAGCGGCCCTGACTGCCTATTTGCCTAGTGTTTTTTGTCC
+TTTTCGGTTGGTTTTTTTGAAAATTTTTCCTGATTTTTTTTGTCGTTTTT
+TTTCCATTTTTCTGAATTTTTAGGAATTTATGGAAGTTTCTCTTTTTTCT
+CCCCCCCTCGAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCC
+TAAGCCTAAGCCTAAGCCTAAGCTTAAGCCTAAGCCTAAGCCTAAGCCTA
+AGCCTAGGCCTAAGCCTAAGTCTAAGCCTAAGCCTGAGCTTAAGCTTAAG
+CCAAAGCCTAAGCCTAAGCCTACTCCTATGCCTGAGCCTAAGCCTAAGCT
+TAAGCCTAGGCCTAGGCTAAAATAAGCTCGGCCCCTTTCTGGGCCAAAAT
+TTCATGTACCTCCTAAAATTGTTTCATCCTAAATAGCCAAAAAACTTGGA
+AAAATCTATTTTTCAAATTTTGTAAAAATGTCAAAGAAAAATTCTCAGAA
+GTGCGGGAAAGTTTGACCCAGAAAGGGGCGGAGCCTATTTTTGGATAGGC
+TCCACCTCTTTCTAGGTTTTTTAAAATCAAATTTAGGTGTTTCCTGGTAA
+GTTTTAGTGGTTTCATTTTTTGTATTCATCACATTTCTTTTTCATTTTTT
+ACATTTTTCTCATAATTAATTTTTGATCTACCTGTTGAACTTGACCCCGC
+CCCCCAATCTTGGTGCCTCAAAGGAATCGGAGGAGTCTAGTCAACAAGGT
+AGATCAAAAATAGAATATGAGAAAAATTTGCCATCGTGTTTTTCGATAAT
+ACTACAGTTTCATACAATAATCCCACAACTTAAAATTCAGCAAATAACCA
+GGAAATGGGCGTGGCTTAGATTTTCAAGGTTTCGTTGTTTTTTCCAGGTT
+GTACTTCTGATCTGAACGGGCTCCGACAAAAAATGCACAAAATTCGTAGT
+AGTGATGTGTGACGTCTGTTCTGATGACTCGAATTCATATTATAAAAGTC
+GAAAAATTCCTTCCGAACGAACCCCCCATCATCCTAACATCATCCAGATT
+TCTGCACCCGCCCGCTCATATAATCTGCTTTTCTTCACCCATAATCTTTT
+TGCTTATTTCTCAATCTCCGTCTTTCTTGCGTTTTTAATTAATTCAAGAA
+ATCAAGCAGTTGTGGTTAATGGCGTTCTACGAATTGCTTTTTTCTTGTAT
+TATGATATTTTAATTAATTTTATTTATTTAGTATCTAGGCATGTACATGT
+GCAAGTTGAGTTGAATAACCTGAAAATTTTGTGCCAAGTTATGGGCGGGG
+TCTTTCATACATTTTTTAAATTGTTTTTTGGCTAAATTTGTATGTATTTG
+CTTTGAAAGTTGTGTTTTTTTTCAATTTTCTTTAAAAAAAAACCAAAAAA
+AAAAATTGGTATGTAGTAACGTAGGTAGGCAAGAAGTAGGTGTGTAGGTA
+GGGACTTGAAAATAGCAGCTATGAATAGGTGCGGTATTTGAAGTTTAGGC
+AGGTTCGTAGGCAGATAGGTGAGTAGAAAAATCATTCAGAAGACATTCAG
+GTAGGCTCACTGGTAAACAGGCATAATGTAGGTACGTAGGTTAACACTTA
+CGTACGAGGCAGTAGGCATCAGGGCTTTGTGGCAACCGGCAACCGGCAAC
+CAAAAACCAGGTTGCCGGTTACCGAAAAATTGCCGAAATTTCAGCAACCA
+AAAGTCGCCAGAATTTTCTCGAATTTTCCAAAAGGTTCTAGAACATTCCA
+GAATTTTCTCGAATTTTCCAAAAAGTTCTAGAACATTCCAAACTTTTCTC
+AAAGTTTCCAAAAGACTCTAGAACATTCCAGAATATTCTCGAATTTTTCA
+GAAGGTTCTAGAACATTCCTGAATTTTCTCGAATTTTCCAAAAGGTTCTA
+GAACATTTCAGAATTTTCTCAAATTTTCCAAAAGGTTCTAGAACATTCCA
+GAATTTTCTCGAATTTCCCAAAAGATTCTAGAACATTCCAGAATATTCTC
+GAATTTTTCAGAAGGCTCTAGAACATTCCAGAATTTTCTCGAATTTTCCA
+AAAAGTTCTAGAACAAGTTGCAGAAATTTTCAGCGTACGGCAACTTCAGC
+AATTGCGGGTTGGCATGTAGGCAGGCAGGCATGTTAGTAGGCAGTTTTGA
+CAGTTTTGAAGTTAACAATCCTACCTGATGCACAAGAAAATGCGCGGCAA
+TTGCGGACCGGCAATTCTACAAAATGAGACGGTTGGGCATGTTCTTCCGA
+TATTTTTTATAAAAATTTAATGATAAAGTATAGAAAAATATTTGTTTTAT
+TTGAAAATAAGTTTTATTTGGCTAGGAACAACCGAAAAAGTGCTCAAAAA
+TTGTCGGAATCTTGAAAATTGCCGTGAAAATTTCCAACATTTCGACTATT
+TCTGGAGATTTTTACAATTTTGTCTATTAAAAAAAAACAGTTACTTTCAA
+ATAAAGCAAATATTTTTCTATATTGTGTCATAAAATTTTAATGAAAAATA
+TCGGGGGAACATGCCCAACCGTCTCATTTTGTAGAATTGCCGCGCACCTT
+GTTAGTTTATCCCCGTAAACCTCCAATCAATAATTGGCAGGAGTCCTTCC
+GTCCGTCCAAAACGTCATAAAAACTGGAGATGGCAAAATTGGAGATGTGC
+CAAGTTTGCTGGAGAGGTGGGGGGAAGGAGACAATCATGTTGTCTGCGTA
+TCTCCAGACTCGTCTGCTATCTCTCTTACCCGGCAAATGGGACCTCCCCA
+GAACGGTGATTTTGTCCTTTCAACACCTTTTTTGTGTTTTTGTTTGTTTG
+ACACCTTTTTTTCACTACTTTGCGGGAATTTAGACTGATTTCTCATGGTT
+AGAAACGTGCTGACGTCACATTTTTCGCGGGAAAAAAAACCCGCATTTTT
+TGTAGATCAAACCGTAATGGGATAGCCATTCTAACAATTCACTGTTTTTT
+TTCTGAACAAGTCTGAAGTTTTGAGTTCAGCACCCGCAATTCTGTCTCTG
+ATAAGTTTGAAAGTTTCAAATTGAAACCTCTCAATTGTCGGACCAGCGCG
+CTACTTCATCATACCCCGCAAATTGAACTGCTCGCGGCAAAATTTAAAAA
+TTGATGCTTCTCCAGAAACATCCCACCAGAAACTACCTAAGACTGAACTT
+CATTAACTTCTTTTAAACTTAAACAACGATCATAATACCTTAAAAAAAAC
+GTTTGTACGTGGTGTCAGAGTGTCTCATTTCATTTTGATCTACATAGATC
+TACAAAAAATGCGGGAGAAGAGACGCAGAGTTTTCAACTAATTTCGCATG
+GTTAAGAACGTGCTGACGTCACATTTTTTAAGACAAAAAATTCCCGCATT
+TTTTGTAGATCAAACCAGCCTGGCACCACGTGCGTTTGTAATCGTTCAGT
+AGGTAGGTAGACACAGGTCAGTAGGCATAGGCAGGCGGTAGGTCTGAGGT
+AGGTGTTGTTGACCACCACGTAGCAAAACATGCTTGACGACTAGCCTCAA
+ACGGATAATCACAAAGTTCTACGTAGTTATGATTTCAAGCCGCCCAATGA
+GCACATTACGCTGACTAAGCCACAGCTATAAGACCCTCCTCCGAGTATAT
+TCATCACCAAACATCCAGTTTCCAGTTTTGCAGTCTTTTTTTCTGTTGGA
+AAATAAAGAGAGTACATCTCATTAGACATTAATGAACAATTTCAAGTTCA
+AAACTATAAATATAAATAAAGCTAGTAATTGAGCCAGTCCAACCAAATTT
+CCCACAAGTTCATTATAAACCTTCCAATTTCCCAATCCCATGTACTCCTA
+CTAATCAGTTTCTTTCCTTCCGCCCTACTTTCCAAATTCATTTATCCGCT
+TTGCATACTTTTCGGTAATCTTGACGATTTTCAGAGGTTTCTAGAATTTT
+TTATTTTTTCAAATTATGCAAAAATAAATTTTTTTTTGTATTCTCAAAAA
+ATTGCTAAAATTGTCCAACTTCCCATTTCTCGGAAATTGACGTAATTGCA
+GTTTTTTGAATTTTTTTGAAATTACTGATTATCAAATTTTGTTGGAAAGT
+TTCCTTTCACCTACACACCTACCATATGCCTATCTGCCTAGGTGCTTACC
+TACACGCCTGCTTCGTGCCTACCCGCCTACCTGCCTGGTTTATTTTCAAA
+AAGTGCAAAGAGCCAAAAGTTTCGAATTGTCAAAATTGCTCGGAAATTTT
+TTGAAATTTTGGAAAATGCCAAAGTTATCAAATTCCGCATAATTCCAAAA
+TTGGCAGCCCGACATCATGCCTGCCTACATTCCTGTCTGCATATAGGCCT
+GACAAAATGTCCATCAATGTATGTACCTATTTCATACCTATCTACCTGTA
+TAAACATAGTTCATCTCTACCTCAAACAGCATGTTACAGGCTTTCTTCTT
+ACCTACCTACTTCATTAACTGCTGTTTATTGACCTGTCTACGTGCCTACC
+TCATGCCTGGCATGCCTACATACCTACCTCATTTATCAGATCCTCATGAA
+GCCTATTTACAAGCCTACTTCCAGCCTACCTATTGTGTTGATTACGATCA
+CCGTCTCTAGGTTGCCTAACCTGCCTAATTGTGTCTACCTACTTAGCTAT
+CTCATGCCTGCCTACTAACCTGCTCAAGTACCTACTTCATGCCTACCGGC
+CTACGTTCCTACCAACGTGCCTACCTGCCTGCTCACTAGCCTAAGTGTCT
+GCCTACATAAATTGTCCGTTAGCACATCAAACTTTTCATATATACAAAAA
+ATTGCATAAAAAGAAGATAATCATTAATAACAAGTGGGTAACTCAAAAAG
+GAAATTGGTTTATCTCCCGGCTCCGAGAGCACCAGCACTTTGCTTTTCCG
+TCACTACAACCTCTAATTTTGTTTTGTTCGAAGGACTTTTTCCGATACAT
+ACTAATTTTTTCGGATCCGGTTGGCTCTGGATTTCAAGTTTTATAATAAC
+TTGGGCTCCCAGTGACGTCACCAAAGGTGCAATTAGCCTTTAGTAACTAA
+ACAGCTTGCTCCTAGTTTACTGCTCCGTCTTCTCAAATGAAACAGAGAGA
+GAGAGACCCCTCATCGAAAATTCAATTAAACGCTAAAACGTAGGTAGGAA
+AGAGAGAGAGAGGGAGACTCCTCCCAAAAAAAAAAGACAGGGGGGCTCTC
+TCTCTCTCTCTCTCTCTTCGAGCGGCAAATCGGCTTCCGAATTCATTCAA
+AAACAAATTATGTGCTCAACCACCACCACTACCACCGGCTCCAGGCGGGT
+AATTACACTTGAAAACCAAGTACTAGGTTTCGTGGCCGGGCAAACTTTTT
+CTTATTAGACCCCGGTGGAATTTTGTAGGTCTATTTAAAATTGCAATTGC
+GCTATTTTGTACTGTTTTTTTTTTGACAAACTTTGAAGCTTGATGTCAAG
+CTGGAAAAGCGCTCTAATGACAATTTTGACTGCAAACTCGCTCTGTTGAT
+AAATGGTCCGTGTACTCCACGGGGGCAATTAAACTGGATTTTTTTCGATT
+AAATAATATCTTGATTTTTTGCAGTTTTGGCTTAGGCTTAGGCGTAGGCT
+TAGGTTTAGTCTCGGGCTTAGGCTTATGGTCAGGGTCAGGCTTAGGCATA
+GGCTTGGGCTTAGGCTTCGGCTTAGACTTAGGCTTAGGCTTAGGCTTATG
+CTTAGGCTTAGGCTTAGGCTTAGGCTTAGGCTTAGGCTTAGGCTTAGGCT
+TAGCCTAAGGCTTAGGTTTAGGTTTAGACTTGGGTTTAAACAGGCTCAGG
+CTTAGGCTTAGGCTTAGGCTCATGCTCAGGCTTAGGCTCAGACTTAGGCT
+TAGACTTAGGCTTAGGTTTTGGCTTAGTCTTAGGTTTGGACTTAGTCTTA
+GGCTTAGTCTCGGACTTAGGCTTAGGCTTAGGCTTAAGTTCAGGCTTAGG
+TTTAGGCTTAGTCTGAATATTTGGCTTAGCCTTGGGCTTAGGTTTAGGGC
+TTAGGCTTAGGATTAGGCTTTGGCTTGCCGGCCACCTGGGATATTGTGGT
+TTGACAGGGGTAGGCTATCCAAATTTTAAAAAAATCGGCTACAAAATTAA
+TATTTAGATGGGCCTATAAACCATTTCTCTAGGCCATCCTGCAAAATTTC
+CAAGACAAAAAATTTCAGCCGTGAATAAAGTTTCCGTTTTCCTAGGCCAC
+CTCCAAATTTTCCACGTCATATGTAAGGTATCGGAGGGTACTGTAGAAAA
+TTATCAAAAATCAGCAAAGAATAATAAGCATTAAGAAAGTTTTTTGTGTG
+TGTGTGTTTTTTGTGGGAGAAAACATTTCCCCTCTCCTTTTTTCCTGCCT
+GCTCATTTGGATACCACCGCTAACCCAACTTGACTTTGATTACCCATTTC
+CGTCCCCCTTCTTCGTCTTCTTCTACTCCGGGATAGAGAGAGAGCTCTAT
+ATAATTACTTTCGTCTTCTTGATCCGTTACCGCCCATTGGCAATTGGTTT
+GAGCTGCCGCCGGAGAATATATACATGCATGTCTAATTTTTTACTGGAAA
+ATCTAGGAATTTTTACGTTGAAAATTTGGTTAAAAGCGTACAGATCGGCC
+CATGCTGGTGATTGTACGAAATTTTAATTTCAAAGTATCTGCAGAGGAAG
+CTAGGCCACAAGCCCCTACGTGGCCGTCAAAATTGAAAACTAGGCCACCG
+ATTTTTTCTCGGACTTTTTATCTACTTTTGCTATTAGGCCCTGTCTTCTT
+TTTTGCAACGTTTTTCTACTAGGTCACCAAATTTTTCCTAGGCCAAGCTG
+CCTAAAACTCGGCCACCGATTTTTATTTGCGTCGGTCTGTAACATTCAGG
+CTCCGACCAGCTCGACTTTTGCTACGTGGTCGCCAATTTTTCCTAAGCCA
+CATCGAAAATGACTCGCTGTGACATTTGTACTTTTTTTCACACGGCCTAG
+AAATTTTGAAAAAAACTCGGCCACTGATTTTATCGGCCTTGGAATCCTAT
+GTAACTTTGTGGCATGATTTTTTATTTATTGTCCATCCAGTTTTTCGTCT
+GAAAATTACAAAATGTTTTAGTGACCGTTGGAGAAAACTCGGCCACCAAT
+TTTTTTCTCGGCCAAGTTACCAAATTACGGGATACCGTGTTCTCTATCAT
+ATTTCTGGCTCAAAACATACTCTACTTCCGTGCTGCCTACGTGGCCGCTC
+AATTAGAAAACTCGGCCATCATTTATTTTCTAGGCCATGTCGAAAATAGG
+TAATGTAAATAGGCAAAGAAATGCGGTGGTTCAAGTAATTTTGGGAAATG
+GATTTTAAAAAGTTGAAAAAATAAATCAAATGAATAAGTCTGAAACACGC
+AAACCTTAAAGCTAGGCCATCAATTTTTTTCTCGGCCAGGTTGCCAATCT
+ACGGGAAACCGTCATGTTTCTTGCTCAAAATTACACCCTATTCTCGAAAA
+ATTTTTTTTACGTTGAGTATGCTCTCCTGCCTAGGTGGCCGCCCAATTAG
+AAAACTCGGCCACCCATTTTTTCTAGGTCATGTCGAAAATAGGCGATGTA
+ATGGGGTAGTTCAAGGAATTTTGCGTAATGAATAACCCCAAAAATGTTTT
+CAATATATGGCCGCCAAAAAAGAGAAAACTCGGCCACCAATTTTTTCTCG
+GCCAGGTAGGCTACCAATCTACGGGATACCGTGCGCTCCATCCTATCTCA
+GGCTCAAAATTACGCCTTTTTTCTCGAAAAATTTTTGCATACTCTCCTCC
+CGTGCGGTTCTTAATTAATGAAAGACGTTTTTTTTTCTCCTTGTCTAACG
+AGTGTATATGCAGAATTCAGGATATGCGTCTTCTTTTCCGAGTTCTTGTC
+TTCAAAGCGAAAAAAAAAGTGTGTGTGTGTGTGGACATAGGAAGACTCGT
+CTTCGAAGAAGACGCTCATTAGCTCATTTCATCCACTCGCTAATTTCATT
+AATTTTGTGCTTCTTCGCCTGCCTTCCGACGTGTTTACCCACACCACCAC
+CACCACCACTCAGTACCTCCTCACTCACCGTGGAGAAAGATGTTCTGGAT
+TTTTTTAAGCTTTTGAGTTTTGTGTCCTACCTCACTTTTTAGGCTCCACC
+CACTTCTTGGCCTGTTATTTCGGTTTATTAGAATTTGTGTGGTGTACTAC
+AAATTTCGATCCGAAAAATGGCAAAAAAAATTCAGCTGACTGAATTTTTT
+TGAACTTTCAAAGGTTCAGTTTTTGCAACCTAAACCTCTCTTAACTTTAA
+CTTTTCAAACCCCGCCCATATCTTGGCTTTTCCAGAAATCCGAGTAATTT
+TTTGGGAAATTTATGGTACAACTAGCTATCAGAACAATTTTTACGGAAGT
+TTTTTTAATTTTATTTTAATTTAAGTCTACTGAAATTGACCTAAAATATA
+TTTTGAAAAATGCTTTGATCCCGAAATTGGCCAAAAAACGTTGATCGAAT
+TTTTTTGAACTTTCAAAGGTTCCGTTTTTGCAACCTTTAAGCCCCGCCCA
+TTTCTTGGCTGTATTGTATTCAAAGTTAAAAGTTGTTCATGTTGTACTAA
+AATATGCAAGTATCATAAAAAATTAACTTTTTAAGCTCCACCCATTTCTT
+GGTTTTTCTGGAAATCCGAGTAATTTTCTGGGACTGTTATGGTACAATTA
+GGTATCAGAAAAAAAATCAAGGAAATTTTTTACTTGGATTTATGTCCACT
+GAAATTGACCTGAAAATGTTTTGAGATTTTAAAAAACTTAAATATTTTGA
+TAAAGGTAGAATTTGAATTCCCCGCCCATTTCTTGGCTGCAGTTCCCAAC
+TGTCCAACTTTTTGAATATTTTCTCAAACTTCATGGCCTAAAATTCCAAT
+TCTAGGCGATCTACCTTGATAAGAACTTACTCCTGAGTTATGTTTGAAAA
+ACATAGTCCATCCGTGGCCTAGAAATCCAAAACTAGGCCATCAGATTTTA
+GGTTCCTAGGCCCAATCACAAAGCCAGCAGTTTTAAGTTGTCAAATTTCA
+GTGGCATAACCTCATAATTTAGACCTATTCTATTAGGTCAGCCTATTACA
+GTTTCTGGCCTAGAAATTTTCCTTGAGTTTGAGCCCACTACCCCCACACC
+CACATGGCCTAGAAACCCAAGCCTAGGCCATGTGTCCCCGCATTCTCACT
+CACTTTTAATTTCTTAATCCACTTACACAATTCTCTCCCCCTTTTCCAAT
+TTCACATCGAACCCGGGAAAGCTCATTAGCTCATTTGTTGTGTGTGTGTG
+AGTTGAAGAAGCGGGGGGAAGGGGAGCCCCCCTTTTGAGTGGACGGGGAG
+CTAGAATGGAAAAAGAGAGAAGGAGGAGAGCCATTTTGAATGGGTATGCA
+ATTAGCAATCGATGCAAATTAATTAAACAAACAACGAAATGAAAGGGGGG
+GGGAGGGCAATCGCCTGCCTTCACTCACATGTCCCCTGCTGGAAATGTGG
+AAATGTAAATTAAAATTAGAAAACTAGCAAAAAAGTGCGTTTTTTATTCC
+TACTTGTTAATTAGTTTAAATTTCTATATATGTATGGCTTTGACATGCCA
+ATTTTGGCGTCTAAGGGTAGGTATAGGTGGGCGATGCACCATGTTAAATG
+GTCGATGCATCATGCCAAATAGTAAATGCACCATTACACATTGAAAATTT
+AGCATTATACACTCCATATAACTGAAATTCGGGGCCCAATCAATATCATG
+CCGCCGACATCTCACGGACTCCGCGCGCCGCTATGTTTAACTCGCAGCGG
+GCGGAGACAGCTGGCCGCGCCCACAACGAGTTAAACACAGCGGCGCGCGG
+AACTCGTCAGATGTCGGCGGCCTGATATTGGTTGGGTCCCGAATTTCAGT
+TTTATTATTTGGAGTGTATAATGCTAAATTTTCAGTGCACCGTGTTAAAT
+GGTCGATGCACCATGATAATGCTAAATAGTCCATGCACCTTGTCTAGAAA
+ACTCGTTGAGTACTGTACTTATGAAACAGTTTAGCAAAAAAAAATGTCAG
+CCTGTTTGGCTCCGCCCCGAAAGTGGGCGGAGTCTAATTTCTTGAATTTT
+TTTTTTTCAAAAATTGTTTTAAAAATAGCTCTGTGAATTCCACCTCAAGC
+AACTATTTTTAGTGGAAAGCAAATTTTTTCAAAATTTTGCGCAAATGGTT
+CTGAGGCTCCGCCTTGAAATTGGATGCTCTTAATTAAGAAAGAAGTGTTA
+GTCCCGCCCCTTTATTGGAGGAACTCAAAACTGGGAGGAGCTTAAGAAGG
+TTATAAAATTTTGCTAATTAAAACACCCAGCTCCGCCCACTTATATATTA
+GTTGACTCCGCCCCACCCATTAAAAGTGGGCGGAGCTTAAAAATATTGAC
+CACGCCCCTTTCTTGGGTAGTTTTAGCGTTTTTCATAGAGTCAATTTTCA
+CGGCGGACCCCGGATCGATGCACCATGATTTGACGCGCAACCCAGGTAGT
+ATGACGTCACTCGTGGCCGAACTCGCGGGGGAAATTTGTACTTACAGCAA
+TAAATTTCGGTGTCTCACGGAGCACCTGCACACGTACCGATCATGAGTGA
+TGCTTCCCACCACAAGACATACACATACACACACAAACCTACTAATTAAG
+ACAAATTATAGAACAAGTGGGGGGAGAAGGGTAGAAATAAAAGTGAGCAG
+TGCGAGAGAACGCGTTAGACGGAGAAGCTGCTCTGGGAGACGTGTGAGAG
+GCATATAAGTTGGATTAGTTTACTGCTCTTTTCATGGGAAAATCAAGTGA
+GCTCCAAATATTTAATCTGACTTTGATTTGGTTTGATTCTGAAATTTTTT
+TGGGATTTGCAGAAAAAATACGTTTTTTTTTTGTATTTTGGAATCGCACC
+AATACGCTGCGTTGCCCTCCTACAGTGCAACTGAGCCACATTTCTCTTCC
+ATAACTTTTTTCTTAATCTCAAAGATTAAAACTCTGCAAAAGCTCAATAT
+TTTATAAATGATAAGGATTAGCAAAGTGTGGGTGATCTTCCAGAGGGGGG
+ATTACCATAATTCATTACTCATTTTTCAAGTTTCATCTGTGTTTTGTTTG
+ATAACCTAGGTGACCTACTAGTTTACCTACAGGGCTGGGACCAAAAAAAA
+AATTTGGACCAAAAAACAAAAAAACAAAAAATTGAAGTTTTTGAAAAACC
+AAAAAAACCAAAAAAAAACAAAAAAAAACAAAAAAAACCAAAAAATTTCT
+TATGCTTAAGTTGATTTTTAATGGGGTTATTCAAGTAATGTTGCAAAATG
+TATTAAAATACATTATGACGTCACAACTGTGTTAAAATACATGTTTTAAT
+GTATTTTAATACATAATAGTCTCGAGTCGAGACTAGACATGGTAAACACT
+TTTTTGGATTTTTTTGGATTTTTTGGTCCCAAAAAACCAAAAAAAACCAA
+AAAATCGATTTTTCGTCAAAATACCAAAAAAAACCAAAAAACAAAAAAAC
+CAAAAAATTCTCAGCCCTGGTTACCTGTCAGCAAATAATTTTCCCCTATA
+TACCACCACTTCAGGAGTAATCAACACCCCAAAACGGCAATTATTTATTA
+TTCTCCTCACCTTCTCAACACTCCATAGCGCCAGCCAGCCTAATTTGATT
+GTTTAATTCGATTCAGGGCACCCCACCACACACAAATTTATTAATTTTTG
+TCTTTCTCGCCATTTTCCAATAATTTTCCCGGCTTGTGTTAGCTTTATTA
+TAGAACTTTTTAAAGCGATTTCTTAGGAATTTATGTGTGACGTCATATGT
+GGCCTAGAAATTTGACGATCTCGGCCGTCGGGGTCGATGAACCATGTTGT
+GATGTATAGGTGGCCTAGAAAATTTTAGGCCACCATGATAGTCGTGGCCT
+AGAAATTTGGGCGCCTTCAGGTGGCCTAGAATGTGAAAAGTGACGTGTGA
+CCTAGTTCTTTTGACGGTCAGGCCAATTTTCCAATTCGATGCTTTTTTTT
+TAATTAAGGTCCATATTCTGCAATTTTAGGCTCCGCCCATATCTTGGTTA
+AACATTTTTTTTTTGCTTTTTTCTGCAATATTCATTCAATCCATCATTGT
+TCTCAAAATTTGATGCACCATGATATGGCAGTGGCCTAGAAAGTGCGACG
+TCACTTATGGCCTAGAAAATTCGAGGATCTTGAAATGGGAGAAAGTAAAA
+AAGTAATCAATGCCCCCTGACGGTCGTGGCCTAGAAAGTTAGAAGATCTA
+GAGGAGGGGAGTAGGAGATCGATGCACCATGTACAGCTACAGTGACGACT
+CACGTGGCCTAGCTTTTTCGCAGGCCACGGCCATAAAAAAATGTATGAGA
+TCGATGCACCATGTTTGTCGCGGACTAGAAATCGAGAATGTGGCGCACGT
+CACGCATGGCCTAGTGACTTTTACGGTCAGGCCGAAACACAGGACGTGGC
+CTAGAAGTCATTCTGTTAGTCTAAGACTCTGCAAAAACTCTCAAAAAAGG
+TGAGCCTATGTGCCTGCCTACTTGCCTACATTCTTGCCTACCTGTTACTG
+CTTTCTAATCTGTACCATGTTGCACCTACAGTACCCCCTTCCGCCCCCGT
+AAAGACTTTTTCAAGCTCAAAAGTGCAGAAAACACAAAAAAACCAAGCCC
+AATCTACAAAAGCTCATCTATTCGTGCTTGGATTAAAATGCCATTAAAAT
+GATTAATTAAGAGATCGAGACTGGTTGAAAACTGATCGGATTAAAAAGCG
+ACTGAGGTCCGCGAATGAGCTTTTCATGCAACTGATGAGCACATTTCCTG
+TGTATGTACACTGATGATAAATCTCCTTATCTTTTCCGAGACATAACAAT
+CTCAATGTTCTTCATTAGTTTCTTCATTTCCTTCTGAAATTTGTTGCTTT
+GATTTATTAAAATCTGTCATTATGTAAGATCCATAATTCGTGATTCGAAA
+TTTTTTACAGTTTTTTTTAAATATAGAAATTTGAATAACTTTCCTACCAG
+GCTGCCCCAATACAGTTTGATCTACAAAAAATGCAGGAATTTTTTGCCCA
+AAAATATGTGACGTCGGCACGTTCTTAACCATACAAAATCAGTTGAGAAC
+TCTGCGTCTCTTCTCCCGCATTTTTTGTAGATCACCGTAATACAATGCAA
+AAATGAGAGAAAAAAATTTGAAAAAAAACCTATCCAAAAATTTGGCATTT
+TCAGATTTTTTTTTTCGAGCAGACCTAAAAATGTTTCGATAAATTCTAGA
+TTTTTTGAAAAACTGTCTGAATTTTTTTTTTTGAGAACAATGATTATATT
+TTAAAGATCAGTGTTGACTTGAATCATGTAGCGTAAAAAAGGTTAAAAAA
+AAACCAAGATATGGGCGGAGCCTAAAATTACAGAAATTGGACCGTAAATT
+TTTCAAAAAATTTTTTTTTTTTCAAAAACCGAAATTTTATTTTAATTTCA
+AAATTTCCGCTTCGGGGTTTCTTGATTTTTTCAATTTCAATTTCAATTTT
+TTAGATTTTTTCCCGTAAAAAACCCAAAATAAATTTACTGAAGCTTCACT
+ATTGGATTAAAAATTTATAAGGTTCTTTGCGGGAAAATTAGTAAAAAATC
+GAAAATATATTTTAAAAGAAAAATCAAAATTAATACAAAAAATTAAGGCT
+TCCATGTAGGTTCGCGTGGTGCCAGGCTATCCCATTATTTTTTCTTTTTT
+TTTTTTTTTCCCCAGGAAAGTGTGACGTCAGCACGTTCTTAACCATGCTA
+AATCAGTTGAAAAGTCTGCCTCTCTTCTCCCGCATTTTTCGAAGATCATA
+CCAAAATGGGGCACTTTGACGCCACGTGTAGACTGTAGGCCATAAACCGC
+CTGCCTGCCTGATTTTCAGGCTACCTACGCCTGCCTGTCGCCCCAATCCA
+CGCCTTATGCTAAAACACATTCATTTCTTAATTTGATTTTCACCAAAGTG
+ATAAAAAAGATAAATTAAAAATTAGTACATTCTCGTCAAAATGCAAAAAG
+AGTCGTAAGGCAGGCAGGTTTCAGGCAGGCCCTGGCTCACGCCTGCCTAC
+GATGCCGGTTACTAAATTTCCAAAATACCTTATTTACTCTACAAATCCTC
+TACCCCGACATTACATCTCAAAACTCATCCTATTAATTTCTGCCTTAGGC
+GATAGCACTACTAATTGATAGGAAAAGACGACTTGTGTGTGTGTGTGTTG
+AATTATTATACTAATTTGATTTTAGGCAGCCTCTTTCGTCAAAAAAAAAT
+AACTTGTGTCACCACACCACACCTCCCACGTTTTCGGTGAGTGAAGCTTC
+TGCTCGCTGTTAAGCAGATATTCATAGGGAAATCATCCGTAAATCCATTC
+AAGTCCTCTTTATTTTCTTCTTCTTCGACCAAATTAGTATACAGATGTCA
+TCAACTTTTTTGTTTCTTTTTGAGGGCCCAGGCTGTTCATTACAGTTTGA
+TCTACAAAAAATGCGGGAAATTTTTTTTTGCTTTTTGCCCAAAAGAATGT
+GATGTCAGCACGTTCTTAACCATGCAAAATCAGTTGAGAACTCTGCGTCT
+CTTCTCCCGCGTTTTTTGTAGATCTACGTAGATCAAAACGAAGTGGGAAA
+CTCTGACACCACGTGCTTTGAGAAAAAATTTGAAAAAAACCTTTTTAAAA
+ATTTGGCATTTTCAGTTTTTTTTCTTTACAAAATTTTTTTGAACGAATCT
+AAAAATGTTTCGATAAATTCTAGATTTTTTGAAAAACTGTCTGAAATTTT
+TTTTGAGAACAATGATGACTTGAATATTGTAGAAAATCGTAAAAATAAGT
+TTTAAAAAACCAAAAAAAAATGGGCGAAGCCTAAAATTACAGAAATTGGA
+CCATAAAAGTTTCCAATTTTTTCTTCACAACTTTTTTCAAAATTGCTGAA
+ATAAAAAAAAACTATTATTTAAATTTAAATTTCAGAAATCCTAATTTTGA
+CGCCGATTTTTAAAATTATAAGGATTTGTTTTTCCTGCAAATTCTTTTTT
+AGAAACTTACAGTTTGTCGGTTTGTCGATAGAGCGTGCTTATTCACCAGG
+CTGTCCATTACAGTTTGATCTACAACAGTGCGGGAACTTTTTTTTTGCTT
+TTTGTCCAAAAGACTGTGATATCAGCACGTTCTTAACCATGCAAAATCAG
+TTCCGCATTTTTTGTAGATCAACGTAGATCAAACCGAAATGGGGCACTCA
+GACACCATTTGGGGGGCCTAGAAACCGGTCCCTTTCTCATTCAAAGTGCT
+CTCTGTTATCAAGTCTCCCACGCTTTATGCATTCAACTTTGTACAGTTCA
+CACGAGCACCCACGACTTGATTATTCAACATTATACAGAACTAACTATTC
+GAATCTCAACATGTCTTCTTGCCGAATTTAATCAACTTTGACTTCTTCTT
+CTTCTTCGACTTCTTTATACAACTACTCATCTTCTAGTTGCCCCTCTAGT
+TGCCTCACACAAGCAAAATTTCTTTTGAAATGAAATTTAAACGAATTGAC
+TAGTCAAAATTTCATCAATTTTCTACTAGAGAGAAGCGACGAGATTGACT
+TTTGGCAAATATAGAAGAGAGAGGCACCGAAAATGAATTAGATTTAACAC
+AACAACGAGTAGATGAGTTGTGTGTGTCAACGATGATGATGATGATGAAA
+AGAGCAGAGGAGCAAGCATGAGTGATTTCTGCGGCGGAGGTCGCGGCGGA
+TGAGGAGCATGAAGAAGGCTAACGAGCTGTATGGCGATGCGGCTAAAAAT
+TGATGATTACTGTAGATTTGGAGCTTTACACCGTTTAACTGGCTACGATT
+ACATACAGACTTGTTTTAGAATATTCTGTATTTGAACCTAATAATACAAA
+TTGCCGGTGTGCCGATTTGTCGGAAATTTTCAATTCCGGCAACTTGCCGG
+TTTGCCGATTTGCCGTAAATTTTCAATTCCGGCAACTTACCCGTTTGCCG
+ATTTGTCGGAAATTTTCAATTTTGGCAAACTGCCGGTTTGCCGATTTGCC
+GGAAATTTTCAGTTCCGGCATTGTGCCGGTTTTCCGATTTGCCGGAAATT
+TTCAATTCCGGCAATTTTCCGGTTTGCCGGTTTTCCGTTTGCCGGATAAC
+AAAGTGTTTAGAGGGATTTTTTTATAAGAAGGAAACTCTTAAAACTGTGA
+CTTTTTGAAATTGTTTCCCGTTTTCTTTCGATATTTTCATAGATTTTGCA
+AGAATGCGTGCAGTTTTGCCAGTTTAGACGTAATTGAATTTCTGAAATTT
+CAAAAAAAAAAGAGCAAAATCATAAATTTTTGACATTTGTCATTTTTTCC
+GGTAATTTGGCGATTTGCCGGAAAAAAATCATTTACCGCCAACTCATGGT
+ACGTCTAACCGCAAAAATTTTTTGGGAGCCTTTTCTGGCTTTCTTTCAAG
+CTATCGTAATGTGACCACACACCTTTCTATAATTTTCAGTATTTACGCCA
+ACCGAGAAGATCACAGTAGTTTAAGGTTATGGTGCAGTTTCTGGTCAATG
+GATCAGGTCTCTTACCGCGAAAATTTTAATACCGTGAATGTGAAGCTTTG
+AAAATTTTCTGCCGTAAATTGTCAATTTTCTGCCGCACTTTGTCAATTAT
+CTCATAAAGGTCACTTAAGTTAGCCAAACCGTGAGCCAAAACTGCCCCTT
+ATTCCTCATGCCGTCTTGGAGGAAATCTAGAGCAAACCCTGGTCCATATT
+CGGACAAGGTCCCCTTTCTTCCCCCAAGCGTCTATCTAACTTTTCCTAAC
+TACATATAACGGAATTAATAATCCTATCCCCAATTTAACGTGTCCTTAGT
+TCTCTCCCTCCTCACCGTCTTCTAGTTTCATCCATGTCTCGCCTCATTTC
+ACCCGATTGACGATCATCTCGGCTCCACACTTTGACACCATAGCGCGAAT
+GAAAAAAAAGAGTGAGAAAAGGGGAAAAAAGTTGCTGCCCTATTATTAGG
+AGTCAAATAGACACACACACACACACACTCAATTTTAATGGATTACGCAC
+GATTTGACACCATCGACACCAATTTGGAAATGGGGGCACATAGATACATA
+CACAAAAGGAGTTGTACTACTAGTTTTGGAACTAACATCATTCTAACATC
+TTTTCATTTATGATTTGATTTATGCAAATGTCCTTGATTCGTGACTTCTT
+GTATAGTAGTTGGGATAAGTATAATCATGGTAGTTGCTCAAGACTAAGCT
+CTTTAGCAGTTTTAAGGTATGCCCCAGTTCGGGATTCCGGCTTGCTTTAA
+GATTGTGTCAGGTCCGGCCCAGGTTGTCTAAAAAATACAGGTCTGCTCCA
+GGACGGTATACCATCACTATATATAAAGCACGTGTCGTTCCGTCACTTTG
+TAGTTTGATCTTTGATCTTTGGTCTTTGAACTCTGTAGTTTGTAGTCTCA
+TCACACAAGAGAGGTCACATAGGCCCGGCCCCTTTTGTGACGTCATCACA
+AATTGGCGGGAAATTCAAATTTTCTGAGAAAATATTTTGGCGGGAATTTA
+AAATTTAATTTTTTGAAAACATTTTGGCGGGAATTCAAAATTTAATTTTT
+CAAAAACATTTTGGCGGGAATTCAAAATTTAATTAGACTGTTCTCGGTTC
+GGCCCAGATATATCCAAAGTCTTTCTCAAGACCACTCTAGATCTGTTCTA
+CTGTTACCCAAGACTGCCGCTCCACACCCTGTATAAGTTGGCCCTAAGGC
+TCCACTGAGTTTGATCTAAATCTTGCCAAGCCTGTATCATACCTACCTAG
+GCCCACCACAGGTGCATCTCTCACAGATCTTCCACAGGTGTTTCTAAGTC
+TGCATCAGATCTGCACCAGGTCTGTTTTTAGTTTTGCCTGGGTGCAGCCC
+AGTAGTCTACCTCACTATCAAGCAGGTCCTGACACCAGTTCCTAGGTCTC
+ACATTCAGGCTTCTAGGCGGATAGTCTACCTAGCTAAAGCTTCAACCTCC
+ACTGTTTTAAAGGCTTCCCCTTTCTCAAACTTCAACTAACATTAATACAT
+ACATATGTTATTAATTCGCGACTCGGCGACTAATAACAATAATTCAAAAC
+CTCTTTCCTGGCAATGCTTCCGGTACTCAACACGGAGAGAGAGGTGGCAG
+GTATCCGGTAATTTATTAACTCGAGCCGCGCACCCTGGCTCCCAGAGCAC
+ACAGCCCCGATGATCGCTCATGCACGAGTACTCACGAGGTGGTGGTGAGA
+GGTAGGTTGGAGAAAGCGGTTCTACCTTCACAAATTTCAATTTCAATTTC
+CTCTCTCTCCGTTTTACTCGGGCCCCCCCCCCCCCCTTCTTTCAATTTTT
+CGCCCCAAATTTGTGCTCCTTTAATGGAAAGTTTTTGAGTGTGTGAAAAA
+GAGAGAGAGAGAGACACCTTCGTGTCACGCCAATTGCACTAATATGTGCT
+CTCCCCACCTAGAGCTACCAAAATGTTCAATTCACAATTTCCGAACTAAT
+TCGTGTCAAGTTTTTAGTTGGTCCTAACTCTTTGGCCTAGAAATTTAGAT
+TTCTAGGTCATCCATCTAGATGCGGTGGCCTAGAATCCTAAGCTTTAGAT
+GCCCAGGCCATCAGGCCTAGATTCTGAAATGTTGTGATTTTTCTAGGCCA
+TCAACTTTGACCCAAAAGCCCTCTAATTTTTAGGCCATGAATCTAGGAAC
+CTATCTAGAGGCCTGATCCTTTGCTTTCTTGCCAAAAACTAGAGATCAAT
+GCCCTAGAAGCTCACAAAACTTTGGCCTAATAATTTCTAGGCCACCAATT
+TTTTAAAGATAGCCTAAGTCATCAACCTAAAATTCACGGCTTAGAAATCA
+TGAAATTCGCTTTTAAGGCCTCTGACTTCATAGCAGTGGCCTAGAACTCC
+AACTGTCAGTAGTCTGTAAAAATGAGCTTTTTGGGCCTCGAACATAACAT
+GGGACATGGAAGCCTAACATTTTTAGGCCACTGACTTTAAAGCAATGGCC
+TAGAACCCCGTTTTTCTGTAGCCTAGACTATCATCTAGAAATCAATGGCC
+TAGAATCCTAAAAATAATATTTTTCGGCCACCAAAATTTTAGGAATGGCC
+TAGAAATCTATTTTGTTGTATTCTAGGCCACCATCGACAAAGGAATGGCC
+TAGAATCCCTAAGAATGTGATTTTTAAGCTACCATCTATGTACCCTAGAC
+CAATATTTAAAATTCAATGGCCTAGAAACTAGAATATTTGATTTCTAGGC
+TACTAACTGTTGTGTGCTGTATCCTAGACTATCATCTAGACCCCAATGGC
+CTAGATTCCTGAAAATGTGTTTTTTCGGCCTGAAATAGGCCTAACATTTT
+CCAGTCCACCAACTCTTTTAAGATGACCTATAAGTTTAATCCTAGCTTGC
+CAACTATAAATAATTGGCCTAGAAGCTCCTAGGCCACCATCTAAAAATCG
+ATGGCCTAGAAACCTCCCATTTTTTGTATCCTAGGTCACCAACAACCACT
+GATGCCCAAGACCCCGGCTTCTTATTTCATAATGAGCAGCAAAATGAGCT
+ACCGTACCCCTTCTACACACTTCCTCCCTCTCCACACCCATTTCCCCTCA
+TTTTCGTCTATTTTAGCGGCGGCGGCGCGGGATAAATTTGTGAGAGGTGA
+GCTGCTCACAATAATGGGCTTGTTGTAATAGGCGGCAGTGGTAGTGGTGT
+ATGGATAATTGTGAGTTCCCAAACACACAAAACTTTTTCGCCGCAATTGT
+TATGCAACCAACATAATAATAATAATAATAATAAGTGAATGTGCATAAAT
+GTGCTCTTTTTCGCGTCTCCACACCCGTCCTGATGGGGACGACGCTTCGT
+TGAATAGTTGGAATAATAATAATAAATTGGAAAAATTTGGGCGCCCCCCT
+CCTAACACCCTAACACACACGAAATTTCATTTCGCGCGCGCTTCGAAAAC
+AAATTGAAGACAAGTTTTTCGCGAGACAAGTTATGATAATTTGTGGGATG
+TGGTCCCCGCCGGCAGCTTCCATCAATTTGGAGCAAATTTGTGCTCTCGC
+AAACCTTCTTAAAGAAGGGTTACACTAACAAAGTTTGTCGGAATCGATAT
+TTTTGTAAGTGGGCCTGAACCCCCGGTCTTTAAATTGATAGGCATTCTAG
+GGCTTCCATGGGAGACAGGCGCGGTTTTAGGGCCTGACGTCTGCCTCTCG
+CCTCATTTCTGCACTATGGCGAGAAGCCAAAGACTTGGTGTTCACACTTT
+GTGCCAGAGTGTCTCATTTCGGCTTGATCTACGTAGATCTACAAAAAATG
+CGGGAGAAGAGAAGCAGAGTTCTCAACTGATTTTACATGGTAACCAGAGC
+GTGCTGACGTCAAATTTTTTTTGGACGAAAAACTCCCGCATTTTTTGTAG
+ATCAAAAACCGTAATGGGACAGCAGGGCTTTCCACCAGAATAATTCCACT
+TCTTCACAATAAACCTATATATTTTTTGTCAAAATCTTGAGAATTTCCAG
+AATTTCAACGAAAACCACTGCTAAAAGTGGTTCTTTCGCCGCGGCCGACA
+CTTCTCGGGTTCCGCGCCGCACTATAAAGGAGGCGCGGCGCGGCAGGCGG
+CGCGAGGCAGGCGTTTTGGCGCCTGCACGGATGCCCTACACCAAACTGCA
+AACATTTCTAGTTCCGTTTTTCGGACTCTACGCCTTATTTCGGTCTTTTT
+GTCACAACTTCGCTACACTGTGTTTTTCTCCACTTCTACGACTTTAAAGG
+AGGGCGCATTTATGCGACTCACGTGATGTCAGGCAGTCTCATTGCGGTTT
+GATCTACAAAAAATGCGGGAAACTTTCCACCAGGAAATTGTGACGTCAGC
+ACACTCTTGCGAGATCAGTTGAAAAGTCTGCGTCTCTTCCCCCGCATTTT
+TCGAAGATCAAACCAAAATGGGACATTCTGACACCACGTGGTGACTTAGG
+ATCAATGTAGATCGTTTTATAGGCCATCCATTGATTTTTAGAGCTCGTGG
+CGGGACCATTTTAAATGAATTTCCAAAATTTCCAAAAACCTAATTTTTTT
+GTCAATTCACAAGTCCCCCGGACCCCCTCCATTGTCCCCCCGTTCACAAC
+TTCCTCCCTCGTTAACCACCCATTTAGCGGGACAAAATTAGCGAATCATT
+GACTCATAATCAAGTAAATCGGTGAATGCTCGACGAGCAAGAGGGGGGGG
+GGGGGGTCTAATCGAATTACGGGGGAAGGGACCCCTCCGCGCGACACCTC
+GCTGCCAATTAACAAGTCAACTACTTGGGGGGGGGGGGGGGCCTCCTCAC
+AACAATGTTTGTATTATATTTCTTGTTATTATGATTATTATTATTATTAT
+TATTAGAAATTAGTTAGTATGAATATATAATATCAACTAAAAACAAAATG
+ACAGTTAATAATAATTGAAGTCATCCAATAGGTGCCAATTAGTCAAAGAG
+AGGGGTCTGTGAAAACAGAAATAGAAGAGAGAAGGCGGGGGAGAGGGGCG
+CTCTCAAATAATTAATCTGGGCTCCGTGGGCTCGTAAAATTCCGATAAAA
+TGGCTTGTTTGTAATTAGCTAATTCACGGAATCTTTTTTTTTTGTTGGGG
+TTTTACTATGTTTTTGAACAACTTCCTGTTATAACATGTTTCAAAAAAAC
+TATTGACCTCAATGGGGACTTGAACCCTGGTGTTGAGATTGGTAGTCTGT
+TAACCAGTACACCAAAAATTGCAATTTTTGATTTTTGTTTTGTCTATTTT
+TTTGAATACAACGATAAGTAAGGATCATTTAGATTTAGAAAAAAAAAATC
+AAATTTTGTAAAAATTTTCTAAAAAGTTATGAACATTCCACTTTCACAGA
+TTTCTGGCTTCCCTCATAAATTGAAATGGAAGAGTTTTTGGCGAACAAGG
+CCAGATGCGTTGCGTGTCGCGTCGCGGCTCGATTTTAGTTGTAATGCATT
+TGTCCGTGTGGAGTCCACGACTTCCCCCGTTGTCCGCCAGACGATTGTAA
+ATGGAGCGCGAAAAATTCAATGAGAAAGGCCAGAACCCCGTGCACTTTTT
+TGTTTCTAAAACTGAAAATTTTGAATTTTGAAATTTTCCTTGGTTTTACA
+GTATACAAAATCTTAGTTAGAGTTCGCAAAAATTATTGACACTGGTGGGG
+GCTCGAACCCCTGAGGTGGCATCCCTGTTAGCCACTGCGCCAAAATTGCT
+AAAACTTCAAAAAAAAAATTTTAGACCGTTTTTAAGGTTTTTAGACTTCC
+GACTCTTCAAAAATTCCTATACAAAGTCTTCGTAAAACTAATGACTGGGG
+GGCTCGAACCCCGGTCATCATATCAGTAGTCATCCCTGTTAGCCACTACA
+CCACTTGCCCAGACGTGTTTCTGGTCTGTTTTACGGTGCAGCGTGGCCTA
+AAAAAAACTAGTCAGCCACCAATTCGAAAAGTCCATAGACCAAGTTAATA
+TAGAAATTCTTCAAATTCGAGCCAACCAACTAATATATTCACTAACCTAT
+TTTCGCCGTGTTCTTCCTGTGTGTGTGTGTGCCCCTAGTTAGGCCTAGCC
+CCCCCCCTTATTTTACTTGCTTCACAATTCAATTGGCCCCCACACAGTTA
+CAGTAGTCATAATCATTTTGTGTCGGGTTTTCGACACATCGTTTAAACGT
+GTTACCTCTCTCGGGGCCCCCTCTTCTCCTACTTCTTATTTGCTCAAAAT
+TTGCGCGTCGAAATTTCTTCGTCGTGCGCTGCCCCTTCCGAATAATCAGA
+TTCACCAATGTATAAAATAGGCCACGCCTCACTTTTTCCACACCCATCAT
+CTTCCCTCAACTTTCCTCTTCTCAAATGCCTAATCAGCCAGTTATAACGA
+GGGTGCTCTTCGTGTGGCGCCCCGCCCATTTTATTGCTCCTCTCACGCTT
+CATTCTCACTTTTTCTGGGGATCCTTTTTTTTGCAGACCTAAAAATTTGA
+GCTCAGCCATATTTTTTTTGTAAATATAATCAAAAAAAAATAGACATTAG
+TCAAAAAAGTTGTTTTAAGCCTAAAAAAATTTTTCAGATAAAAAACGTTT
+TTCTTTAACTTTTTTGAACAGTTTTTCAGTGAAATATTTTTAAATTTTTA
+TTTTAAAAAAATGTTTGTTTATCTAAGCCTAAGCCTGAGCCTAAGCCTAA
+TAACCCTAAATAGCGTCAGTGTGGGAGCTCACGCTCCCCCACTGACGCCA
+AGCCTAAGCCTACGCCTAAGCCAAAGCCTAGGCCTAAGCCTGGGCCGAAG
+CTGAGACCTAAGCTTAAGCCTAAGCCTAAGACTAAGACTGAGTTCAAGCC
+TAAGCCTAAGACTAAGCCTGAGTCTCAGCCTAAGCCTAAGCCTAAGCCTA
+AGCCATTTTTAAAAAGCTTAAAAATTTTTGCAATTACTATTTTTTCTGAA
+AATCTGTAAAAATATCGAATTTTTAGAGTTGCTATAAAATTTAAAATAAT
+ATTCAAAAAATAATCCGAAAAAATTAAATTTTTTTTCTCAAAACGTAGAT
+CATACAGAATCAGCTTTAAAAAATTCAAACCATTTTTCGTTTCAAAAATG
+TTCAGAAAATTTGTAAAACTTGAGTTTTGAAGAAAGTTTTCATAAACTAG
+CTCTTGAATAGGGTTTTTAAGTAGGCGTTAAAACGCTTGCCTGCCTGACC
+TTCAGGCGACTTTCGCCTGCCTGCTTGACTTTCAGACGTTCTCTGCCTGC
+CTGCCTGACTTTAAGGCGACCTCCGCCTGCCTCTCGCCTCAATCCGAGCC
+TTATCTCTTAAAATGTTTTTCATCAAATTGATAAAAATACGGAAATTACA
+AAATTTTGTAAGTTCATGCCAAAATGCAGGCATCAGGCCCTGAGGCCACG
+CCTGCCTAGGCCTCCGACTTTCGTTCTACAATTGTCGTTGCCGTTTCCTT
+TATCCCATTTTCATACCCCAAAGTTATGATTTTTCTTACACCCCTTGCGC
+TGCTGCTGCTTCCGCTCCCGTGATCTTATGAATCAGTAGTCAGAACTGCA
+GGTGTGAATCTCCACAATGATCACCCAATAAACGCGAAACACCATTAGAA
+ACAAAGTGTCCCCCGTTTTTTTTTTCTGAGAGTGTCGGCACCCCCCTAAC
+ATATGCGGGGAACATTGTCTCAAGTTTTGTGTGCTCCTCCAGCTCCTCCA
+TATGGTTACCGTAGTCCCCTGTCAGTGTTGTGTAATTGTTGTTGTAACTA
+TCCCCCGAATACCTCTCCTCACATTCATTCACAACACAGGTGTCAACTCA
+ACTCTCAGTGCTCATTTGAAGTTTATGAAGTTTAGCTTCCGGGGATGGCT
+CTCCTGGGCTCCCCGCTCCCTCGAAAATTTAATTAATTGCAAGCACATGT
+GGTGGTGGTGGGGCGAGCTCCGCGCTTCCCCCCCCGCCCCGATTCTCTCT
+CTCTCATTTGCGACTCATTAGATTTTAAATCACTCTCAAACTTTCCACTT
+TTCCAACTTTCGCGTTTTTTAAATTTTTTTTTCACTTTTTCCTCACAAAT
+TCATCCAAAAAAATTTCCAGAGTTGCCCCGCCCATATATTGGCTAAATGG
+TAGAATGGACGTGGCACTTTTGACAATGGATGACAACAACAAACCGCCGA
+CAAGTTCAGAGTCTACGGAGAGTAGGGGTGAGTTTGGCCGGGGGACCGAT
+AATTTTTAGGCCAAGACTTCTTTTTTTTTAAATCATTTTCAAAGGTACGT
+TACCTTCACGTGGTGCCAGGTTGTCCCATTGCTTTTTGATCTACAGAAAA
+TGCGGGATTTTTTCCCCAAAAAATGTGACATAAGCAAGTTTTTAAATCTT
+TTCTCCCGCATTTTTTTGTAGATCTACGTAGATCATACTCTGACACCACG
+TGTACCTTGAACCTCCTGGCTTTCTGAAACTAGAGTTCGTCGCTAGAGCG
+CATTTGCATTGTCGTGGTATTTAATTTACAGTACCGCCAGAATCATGTCG
+CGCCGCTTGTAGTCTAGTGGTTAACACGCTTCAGCTCTAAACAATAGGTC
+CGGGGTTCGATTCCTTGCAAGATGAAATTTCTTTCTCAAGATGGAGGTAC
+ATATGTGCTTTAAATGTGCACTAGAGATAGCGAAACTGATACCATGGTCC
+GACATGTACAGGGTTCCGCGCGCGCCTAGGGCCTCCAAAACGCCTGCTGC
+TCCAGTTTTGCGGCGACCTCCGCCTAACTCGCGGCGCGCCTTCTGTATAG
+TCACGGCCTTCTGTCTTCCCTCATAAATTGAAATGGAAGAGTTTTTGCCG
+AACTAGGCCATCTTGGCTCGGTCACATCTGGGCTCGATTTTAGTTGTAAA
+ACTAAATGTATTTGTCCGTGTGGAGTGCACGACTTGCCCACGCGTTGACC
+GGCGGGCGATTGCCAATGGAGCGCGAAAAATTCAATAAGGAAGGCCAGAA
+CCCCGTGTATAGTGCCGCGCGTGGAGCCCGAAAAGTGTCAGCCGCGGCGG
+AAGAACCACATTCCATAGGACTAAAAAACTAAAGTTCTCTCTTTCAGAAA
+CATCACCACCAATGATGCCAGATTCTGCGGAGATAATGCGACTTCTTACG
+GATCCTTCGACGGCTCAGATGTTTGGTAGGTCATAGATCAAATTTTTTCC
+GCAATTTCCCGAAAAATTTCAGCCAACGAAAACACAAAATGTCAGCTGGG
+ACGGATTCTCGCCGCGTCAGGCTTCGACGAGGCGAGCCTCTCCTCCTCGT
+TTCCGTTCGATCCGACGCTCGGCGCGTTCGCCGACATTTCCCAATTCTCA
+TCACTCCGAAATTCGTCGAAAACGCTGAAATGTCCAAAGTGTAATTGGCA
+CTACAAGTACCAGGAGACCCTTGAAATTCATATGAAGGAGAAGCACAACG
+ATGTGGATGTCAAGTGCATGTTTTGTGCCGAGAACCGTCCCCACCCGAAG
+CTGGCTCGCGGTGAGACGTACTCGTGCGGTTATAAGCCATATCGATGCGA
+TTTGTGTCGGTACAGTACGACGACAAAGGGCAATTTGAGTATTCATATGC
+AAAGTGATAAGCATCTTCATGCAGTGCAAGAGCTCCCGAATAGTATAGGT
+AGGTGGGGGGGGGAGGCGAAGGGTACTGTAGTTTTCGTGGTGGGACCCAA
+GAATTTGAATTTCACAAGAATTTAACTGTTGAACTCGAACTTTTCGATTC
+TAGGGTCTCGCCACGCAAAAACACTTACGCCAACTTTTTTGAACCCTAAA
+AAATGATACTCAAATTAGAGTTCTCAGTGAGCTAAATTCGATTTTACAGT
+ATTTTTTTAATTTGACGTTCTGTGGGTCTTACACTCAAAGGGTACTGTAG
+TTTTCGTGGTGGGACCCACTTGTCCAAAAATGGACGTGATTATATTTGGA
+TTAAAGCCCCTAACTTTTCTGATTTTTTTAATAAATTGGTTTTATTTTGA
+AAAGACTGAGAAAATTGAGTTTAGATCGAAATCAATAAAAATCGCGTCGA
+GACCCAAATTTCCCGGGTCTCGGCACGAAAATGGGGGAGAGGGTACTGTA
+GTTTTCTGGCTTCTCTCATAAATTGAAATGGAAGAGTTTTTGCCGAACTA
+GGCCGGCCATATCTGGGGTAGATTTACGGCGCGTTGCGTGTCGCGGCTCA
+ATTTTTGTTTTAAAACATGAGGAAGACCAGAATCCCGTGTTTTCGTGGTG
+GGACCCAAATGGGTCATGATTATACTTATTTGAAAGGCCTTAAGCTGAAT
+TCAGATTTAAGATTTTTATTATTTTAATTCAAAAATATCCTGAATTTTCC
+AGAATTCGCAGCCAACTTCGCGTGTGGTGCTCCAGTTAGCCGAAGTAGTC
+CAATCGAAGAGTCCGACGGATCCCTGGTCTGCTTGATCTGCGGTATCTTC
+GCCACCGAATCTATCGCCGAAATGATGGAACACGTGGAACAAGACCGTTC
+CAGGACGTTCCAAGGAGACGTTACCGTCCTAAACGGGAGCTTCCGGTGCC
+ACTTGTGCCCGTATAATACCACATTGAAAGCCAATTTTCAACTACACACA
+AGGACGGATAAGCATCTGCAAAAGGTTCAAATTGTGAGTTTTGTATTCCC
+CTCTCATCATCTTCTTATTTTTATTGTGTCGCCCTTTTCCCATTTTTGTG
+TGTCTGTGTGTGTATGCGCACCGATTTGCATATACACATAAATTCATGAT
+TTAATAGCGTAATGAGTAATATTTGCTTTGCCAAGGCTAACAGTTTTCGT
+ATTTTAAAGCCTTTTTTCTACAATTTTTGAAAAAAAAATTCAAAAATTTG
+AACATTTCAATATATCCCTAGAAAGCTCAAAATTGTAGTGAAAATTTTGA
+ATTCAGTACGCTGAGACCTTTAAAATAAGTATAATCATTACTAGGTTTTG
+GTTCTGACGCGAAAGTGTTCGTGGCGGAGCCCAAGCAAGGCGTAATTGAT
+TATAGGGTCTTTGCACGCAAAAAATTTAAGGTCCGGTAGGCGTGGCGGGG
+AGTTTTTCTTGAATTATTTTAGTTTTTCATAAATTTTCAATTTTTTGGAA
+TTTATTTTTCTCTCCCTTCCCCCGCGTAGTCTGAGCCTAAACCTAAGCCT
+GAGTCTAGGCCTAAGCCGAAGCCTAGGCCTAAGCCTGAACTTAAGTTTAA
+GCCAAAGCCTGAGCCTAAGCCTAAGCCTAACCCTAAGCCTCAGCCTCAGC
+CTAAGCCTAAGCCTAAGCATAAGGCTAAGCCTAAGCCTAAGCCTGAGCCT
+AAGCTTTAGTCTAAGCGTAAGCCTAGGCCTAACCCTAACCCTAAGCTTAA
+GCCTAAGCCTAACCCTAAGCCTAACCCTAAGCCTGAGCCTAAGCCTAAGC
+CTAAGCCTAAAGTCTTCGTGTCGAGACCCAATTATACTCAATTGAAAGCT
+CACAATGAGCTGAATTCAAATTTCTCAATGAAAATGTGAAATACTTTGAT
+TTTACGGTCGGTGGCTTTACTCCCCCCGAACTTTGGAAAAAACTCTGAAA
+TTTTTTTTTCATTGAATTCCAACCGGTTTCTACTCTCTCCGGCTATTAGT
+GTATGTGTCTTTCACTTCTTTGTTCTCGTCGGGTTGTTCCCAATTTCCAA
+CCCTCGTTTTACTCATTCCCCCTCTCATTTTCCCAATCCAATTAGTTATA
+CCTATGGGGGGAGGTGACGGTGATGATTCTCGCCATTAAGACCCCCCCCC
+TCTCCTGGGCCGATTGAGATGGAAACAAAACAAAACTGTCAATTTGAATA
+AATTCGCAATTTGACGCGGGCGGCGCAGCGGGTTGCCGAGAAGGATATAA
+ACTGGGGAACTCTACTTAGCCCGTAAGGTGTCGGCTGCTACTATTTTATC
+ACATCTCAATTTTTACGGAATCCCGTAAGGCGTCGGCTGCTTCTCTGTTT
+TTGCATGTTTTTACAATTTCGGCCCGTCCGATGTCGGCTCCTTCCAATTG
+TTTTGCAAAACAATTTAAAATTTGAGCCAGCAAGGTGTCTGCTGCTCCGG
+CTAGATTTCCAATATTTAAATTTTGCACAATCCTGTAAGATGTCGGGTGC
+TTCTCAGTTTTTACAAAGTTTTTTCTCAAATACGGCCCGCGCAGTGTCGG
+CTGCCACCTCGTATGTTTCATCAAACTTGAACGATTCGAGCCCGTTAGCT
+GCCCGCTGCGTCTTTTTTTTTCTCAAAATTCCAGCCCGTAACTTTTCGGT
+TGCTGAAATAAACAAAATTTTTACGAAATTTTAACCCTTGAAGTGTCGGC
+TGCAAATTAAGATACCTACTCATTCAGATTCCCGTCTCTCCCTCTCCCTC
+TCTCTTCATTGGGGAGTCCTTCTCCCGAGAGAAAATGAATAAAACTGTCA
+ATTTGAATAAATGCACACAGCGGGAGATGTTTTTCTGTGAAGACTCCACC
+GTCTTCTTCGTCTTCTGCCTATTAAGCGATGATCCTTTCACTTAACTGTC
+GTTCCCTCCCCCTCTCCACATACCAATAAACCTTGCCAAAAGGTCGAGTA
+TGCTTTGCCCGCCATCGTGCCGGAGGTCTTTTTTCTAGACTATGATGTTT
+TTTTTTGGAAAAACATTTTTCTATGGATCGATGCACCATGATGCCGAGTT
+GCCGAGTTTTCAATTTAATCAATTTTGAGATTTCAATTTTAGTCCCTTGT
+ACATATTAATTTTTTTGGAATTAACATTAAAATTTGATAAACTGTAGCTA
+CAACTATTTATTTTTGTGCCAAATTATACTATCCAATTTGACTTGTCTCT
+TGATGCACCATGACTAACTTTCTAAGATCTCATATTTTGGCCTAAAATTA
+TTCTCAAATATTTAAATTTAAACTTTAATCCTATTTTTTTTAATTCCTCG
+GAAAAAACCCCGTTAACAGAATTCCCAATTTGGCCTCCAGGAGCTTTTGT
+CGATGCACCATGTTCAACATTTTTTCAAAATTTTGCTCATTTTGACCTGA
+AATTTTGTCATTTTTTTATGTTGCAGGGTTTTTTATTTTGTGATTTTTGC
+GATGAAAACCACATTATGTGGATGAAAAAAGTTTGGAATCTAGTTTTCCC
+GTTAGGCTGCCATATTGCTATGTAGTTGATGCACCATGTCCAGCTTTCTG
+AAATTTTACTTTTTACATTTTTTGCTCAGTTTGACTTTAAAATTTTGTTA
+GTTTGACCTTAAAATTTTGTCAGTTTGACATTAAAAATTTGTCAGTTTGA
+CCTTAAAATTTTGTCAGACATATAATTTTTTTGTGTTTTTTGGTTAAAAA
+ATTGAAGGTTTTTCGCGATATTTAACACATTACATGGAAAAATTCTTTTG
+ATCGAGTTTTCTAATTTGTTCGTGTAGCAAGTCGATGCACCATGTCCAAT
+TTTTTAAAATTTTACTTTTTTTAAATTATTTGCCCAGTTTGACCTTAAAA
+TTTTGTCAATTTTACCTTAAAATTTTGTCAGTTTTACCTTAAAATTTTGT
+CAGTTTGACCTTAAAATTTTGTCGGTTTTACCTTAAAATTTAATCAGACA
+TATAAACTTTTCTGTTTTTTGGGTTTAAAAATTGATTTTTTTTGCGTTAT
+TTAACACATTAAATGGCAAAAAATCATGCACCATGTCTAACTTTTTCCAA
+AAACACTTGATTTTTCCCTAAAAGTTTGTCAGAATTATACATTCCTTAAG
+TTCAAAACCGTACGGAAAAATTAGAACCCATGTCGATGCACCATAAGCTT
+TGGCTCGCTGAGCTTCGTTGCTGCTCCTGCATATCTCTTACCCCCTCTCG
+CCGCTCTCAGAACATTGACCAATTACTTGGGCGGAGCGCCGTTTTGAAGT
+CGATTGGCTGATGAGTGTCCCGCCCCGCCCCCCGTCCCGCAAATTTTCGG
+AGGAACTTTGCACTGCACACACACACACACAAATACACAAATACACGCCA
+ATTATTGTCGATTTTTCTTGAAAATTTCTTCATTATTGTATATTGACTTT
+TTTTGTCGTCCTCTAGTCTTCCGCCATCCTCGGCGTCTTCATTCGTTTCA
+TTATTTCATACACCTGTTACCACTTAATTCGCCTATTATCCTCCTCATTA
+CCTTCATTTTTCGGTCGGCGTTGACGTCGACATTGGCGCCCGAAATGAGA
+GGAATAGGGGGGGGGGGGGGGGGGTATAGACGACGGCGACTACGACAACC
+ATGATGACGATCATTTTCGTTCTATTCATCTAATCCTGCTAACCGTCGAT
+TTGTCCCCCTCCGTTTTTCAACTTACCAAAACTTTTCGGTTACCTTGGGA
+ATTGGTCCCCTTTTATAGGCGCGTAAATTGACAACATATTTTGCTCACTT
+TTTCGAAGTTTCACAATTTTTAGTTAGTCCGTTTTTTCAATCTGGCCGAG
+TTTTCAATTTTCCCCGGCCAGGGAATTCTAGTAGTATTCACATAATTTTT
+CTTATTTTTGGTTTTCTAGGCTACGATAAAACTCCCTATGCCCGGCAAAA
+CTTCTAGGTCCCCCATTTTACACCTGACTTCCTACCTATCTGAAATGCCT
+ACTTGCCTTTCCACCTGACTAAGATGCCTACCTACCTAAAACCTACCTAC
+CGAACTATAAGATGACTCCTTACCTACATAAGACTTGCCGATCTGAAATA
+CCTACCTACTAAGACATGCTACCTAGCCTACCTATCTAAGATACCTACTT
+ACATATAATGTACCGACACAAGACTTGCCTACCTACGCAAGGCATGATTT
+TTTAGACCTACCTACCTGTACTTAAGATTTAAGACCTAGATCTTATTACA
+TAAGAATTTTCATCTTAGATACCTACTCAAGATCCTACCAAAGATGCATG
+CCTACCTATGACCTACTTACTTAAGATACCTGCCTACCCAAACCATACTA
+CCTAGCGCTAGCGCCCACCTACCTAAGATACCTACTTACCTATAATTTAC
+CTACACAAGACTTGCCTACCTACGCAAGGCATGATTTCTTATTGTTAGAC
+CTACCTACCTAACTATAAGTACTTAAGATTTAAGACCTAGACGTTATTGC
+ATAAGACTTTTTGTCTTAGATACCTACTCAAGATCCTCTTACCCAAGATA
+TACCTAGATGAACTTCCGACCTAAGATGCCTACCTACCTAAGCCCTGTCT
+ACCTAAGACCTACCTATAAGAACTTCCTACCTAAAAACACCTACCTAAAA
+TAAGCCTTCAAGCTCAAAAATTTTTAGAGCATCTGCATGAGATAAGGCTG
+AAAAATATTAACGAATAAGTGGAGAGCGATTAAGTTCCTGCCCTCTTAAA
+GTTCGGAAGTAGGCGCCGCAAAACCCCATTACTATTGCTCATCGAGCCAT
+TTCCGGTACTCAGTACTTTTTCATCCCCCACTCACTTTTTTCTCTCTTCT
+CGATTTGATTTGCATTCTTTTTCCCCTCGAATTTCGAGCTGAGCCCGGTT
+GATTTCCCGCACTTTCTCAATTCTTTCCTTAAGCCACCCCACTTGACCAG
+GAGCAGTTCATTCAAACTCGCACTTAATCATATTATGACCCCCCCCCCCC
+ACCCCTCTTAATTTCCTAATCCCCCTCCCCCTCCTCCTCATAATGACCAA
+AAGACAATTGCAGGCGAACCATCTTCGTGAGGGAACCCGTCCGCACACGG
+CAATCTACCGTCTGTCGAGCACAAAGACGAGCGTTCAAGTGTTGTGTCGA
+CAGTGTCAGGAGGTGATTTCCAGTGGCGAATCGCTCCGCGAGCATCGACA
+CTTTCACGCCCTGCTTGCCGCCAAGCAACGCTTGTGGCGATGCAAGTTGT
+GTAGGCTGGAGTTCGACTCGGTTCTTCTTGCAGCTGGTGAGTCTTGATAG
+TTTTTTTTAGGAAGAAATTATATCTGTAAGTCCCCCAAATATAAGGCCCC
+CATGTCCATCTTAATGAAGCTTCTGACTTAATTTTTACTATAGATTTTGA
+ATTTTGTCTATCGGAAGAAAAATTAGGTTCACCATGATTTTTCGATTTTT
+TCGATGCACCATGATTTGTTGCTAGAATAGAAAACAATTCGTGGCCAAGT
+TTTTTAATTATTTCTTTTTGTCGGCCAAGTTGCAAAAGTCACCTTTTGTG
+TATGGATGCACCATGACCCTTTTCAGTGGATTTTGGCCCAAAAATCGTCA
+AAATTTTGAATTTTTAAAAATCAAACTCTAAATTACCTTTTTTTTTCAAA
+TTTTCTTAACAAATTGGAGCATTTTAGAAAGTTCCGATGCACCATGATTT
+TTGCTAGAATTGAAAAAAAAATTGTCGGGCAAGTTGCAAAACTCACATTT
+TATGTATCGATGCACCATGACCATTTTCGAAATTTTGCGGTATCTATTCA
+AATAGTGCACATAGCCGTAAAACATTGGTGGTGGCCTCGTTTTCTCATGC
+TTCGGCCACGAAAAAAAAAATTCTACAGTTTTTTGGATCGATGCACCATG
+ATTATTTTTCAGTGAAAGCCTGTTTTTGCTTAGCTCAAAGGCCGGCTTAA
+TGTTCCCACAAAACGTAATCCAAAAATTTAAATTTTACCGTCAAACTTTT
+AGCCTGGCGTACACTAAAAATTGTAAAGTTTCAATATATCAAAAATATTT
+CTGGCCTATAAAATTAAACCTGAAAGCTTAGAAATCCAAGATATTTTTTA
+AAAATTGATGTCCAATACATGGGTGTGCAGCAAATCTTAAAGTTTGCCGT
+GCTTAACAAACTCCGAAAAAGTGTGATATTTTTTTATGCTTTTTGGAGCA
+CCAAAACTACTGAATTCGAGCTTAGCAAACGGCAAATTCGGCATATTTGC
+CGCACACCCCTGGTCCACTAGTTAAGCAAAACCCACCGCTGAAAACTAAT
+CAATTGGTGTTTGAAACGGTGTGTGCTACTACTAGAATTTCGCTGTTCAA
+AATCTCTTTATTAAACACTTCTTTGTGTCTATTCTGCCCTTTCCTCCTCC
+CCGCGCAAAATCCACTTGTACCTCTAATTACGGTCAACAAGTTTGCGGGT
+TTAGTTTAGTGAATGAATTGTGAAATGAATGAATGAATGAATGGATAGGT
+AGGTGTGTATGTATGTGGAAAAGTGCGACACACACAACCAGCCGTCCACC
+ACCGCCACTACCACCAGCAGTAGCAACAGCCATCAAATATAATCCTTGCA
+TTTCATTATTTCATAGTGTCATAGATAGTAGCAGGCCCGAGGTCCGAAAG
+GCCTTGACAGCGGTTTATATTCATTTCATTTGACACCCCCCCCCCCCCCC
+CCCCCTCCTACTATTCTTCTTCTCTACCACATACATTCACATAGTCAGGC
+CATTCATGTTTTTCACACAATTTTGTTAATAAAGCCGCTCTGGCGCCACC
+TCTCAGTAGTCCTTCTTCTTCATCATCATCACTCCCTCTCCCTTACCAAT
+AACCAAAAACAGTCATTGATGCGTATCGGAATTATAATCGCGCATTTATT
+GTAGGACACATGACTTGCCACGAGCCGTCCACTTGGCCCAACGAATCACT
+TGGTGAGTCTCTTTACAGTGAATCTTGAAATTTGTGTTGTTTTGTTGTGA
+AATATTGTTAATCGTTTTTTTATTAGTATCTCCAATTAGGCCAAAACTAT
+AATCGTGAAAGAATAGTTTCTGCACATGGTGCATCGACCTGATATATCTC
+ACTTTTTTTGGGCTTCATCAAAAACTTGTTAGCTAATTATAGTTAAGCAT
+CACATCTATTGATATGTTCAATTTGAACAGAATATGGTGCATTGCATTGT
+ATTGCAACTGAAACAATTTTATTGGCGCATAACATTCAACTATGTAGTTT
+ATGTACATCGATCTTAATTACCGTATTTCCTCTATTAGTATTGCACCCGA
+CTAATTAACTTTGAAACGTTATATCTCGGTTCATATTGAAGATATCAATA
+TATAATTAACTATGAAATAATAGCAAAAGAACTAACAAATATTTTGTTAG
+TTGACCATTTTTGAATAGGACAAACGATTACGGAGATATAAGCTGTCAAA
+AGTGGACAATGGGGTGCAATACTAATTGTGTAAATACCTTATATCTCGGT
+TAGCTTTGGTTTTAACAAAAATTTTAAACTGACAAAATATAAGTCATCTA
+AATGTCTATAGTTTTGTAGTTAACAATTTTTTGATATCTTTAAAATGAAC
+TAGCGATTTTCGACATGGTGCATCAACCTCAGTTACCTAGTCTAACTTTG
+CTGGCTTATTTCTTAGTTTTAGTATTAACCGTTCATTTTAATATACTTTT
+ATAGATAGTTAACAATTTTTTGATACCTTCAAACTGAACCGGAGCGATTT
+TAGACATGGAGCTTTGATCCTATCTTGCCTTAATTTTCAAGCTTATCTTT
+TTGTTGTAAAAAAAATTTAGACATGGTGCATTGACCTGAACTACCTGATA
+TATCCTACTTGATATATCTTCAATTTTAGCAAGTTTTGGAAAAAAAAAAT
+TTTAATGAAATCGATTTTTTTTTTCAATTTTCAACCTTCCGGCCAAAATT
+TTCAATTGAGTTTTGACCTTTTTTTTTAACCCGGCAAAAATCTAAAAACT
+CCCAAGAACAATCTCCCACAAAAAACTAAAAACTTGTGAATCTAGATTAG
+TCAAAAATTTGCACCTTCTTCCCATGGGATGGCTCAATCGAACCCAGTTG
+ATGAATCGGCCTGTGGGCCGCGAGCAGTCGCCGCTCTAATTTGGAGCATT
+TGTATATATATAGCGAAGAATTTCACGTGACCAATGAAACCAATAGAAAT
+CCAATCATATTTTTGTTTTGTCTCTAAATCATCTCTTCCCTCTCTCTCTC
+TTGCCCCTCCTTAACCAATCAGAGACGCACACACCGCACCGCCCGTCCGT
+CATCGTCATCGAGTTCCGCAATTAGTCGTCTATTCTCTCCGTTTTTGATT
+GGAGATGGAGCGAAAATGAAAGAGAAAGAACGAGAGAGAGAGAGAGAGAT
+TAGCTCTTAGATTCATTCAACTAATCTTGAAATAACACACACACACACAT
+ACACAAATGAATTATCTTCATTTCAAATCATGGAAATCAGCAAATTCGCT
+AGAAATTTCATGGAAGGGGAAGCTTGAATTAGGAGCACTACTTGATACCG
+AGTTGGAATTGTAGTCTTTTAATATTTGAAGAAATATCACAATTTTTCAT
+TTTAAACTTCTAAAAATATGCAAGTTACTTGATGCATCATGCCTCTTTAG
+ATAACGTTTTTTTTAGGCTTAGGCTTAGGTTTAGGCTTAGACTTAAGCTT
+AGGCTTAGGCTTAGGCTTAGGCTTAGGCTTAGACTTAGGCTTAAGCTTAT
+TCTTGAGCTTAGGCTTAAGCTTAGGCTTAAGCTTAGGCTTCGGCTTGGGC
+TTAGGCTTAGGCTTAGGCTTAGGCTTAAGCTTAGGATTAGGCTTAGGCTT
+AGGCTTAGACTTCTAGATACTTTCTCAAACCACCAAATTACTGTATATTC
+TCTATCATAGATACTACTTCCATTTGGCAGCTTATAACTCAAGTCTTTTG
+TTAGAGATATCACTAGCTTTAATTACAACATTATAGGTTAATAAATACAC
+CATATTTTGTTAGTTTAAATTTTTTGATTAACCTAACGAGAACCGAAATA
+TGAGTAGTCAAAGATTATCGATGCACCATGGTACTACACTTTACTTTGCC
+GGCTCATAACTCGGTTTATTTTCAGGATATCAAAAAGGTTTTTACTACAA
+ACCTATAGAGAAACATATAATAAAAATATTACTATTTTGCAAAATTTTGG
+TAAAACTAATAAGAATTGAGATATAGGCCGTTGAAGTTGCATGATGCAGT
+TCAAAGCCTACGGTTTTAGACTTATAGCTTTAAAAGGAGGTACCGTATTT
+CCTCTATTAGTATTGCACCCATTGTTCAACTGTGACATCTTATATCTCAG
+TTACTGTTTGTTCTAATCAGAAATTGTCAACTAACAAAATATTTCTTAGT
+TCTTTTTCTATCATTTCTTAGTTGACCATATATTGATACCTTTAAAATAA
+ACCGAGATAAAACGTTTCAAAGTTAAGTAGTCGGGTACAATACTGATGGA
+CGAAATACGGTATTGAATATTTTGATCTACGTAACTATTTGATCTAAAAT
+CTCGATATCATTTTAATTTCTGATCCATAGCTTTGCGTTCAATTATCCTG
+CCTAAAAAATCTCTAAAAATAACGTCTACGAGAGCGGGTGAAACAATAGG
+TGGTTAGATGTAAGTTGATACCCCTGAAGGGCATCCGGGATCCCCGCGCA
+AAAACAGTACAAACATGAGATGTACAATCCCCCATTTTTTTGTGGTCGCT
+CTAAGTTGAAATCGATGCAAAGACATTGTCAATATAGCCGTGACGCGACG
+GGCGGGTGGGCTGGCGCGCTCGATGAATCAAGATCGTTTTGGGAAGAGAG
+GGACTGAAAATATTAAAACAACATTTGCATTTTGTAATTGTTTGAATCAT
+CATCATCATCATCATCATCAATCATATCATAGAGGTGGCGAAACTTTTCC
+TGCTGGGAATGTGTCTCCTTTTTAGTACAGTCAATAAATGTGTCACTTTT
+GAACGGGGGAAAAGCTTTTCTGCTTTTCTTCGCTCTCCACCTCCTTCCCT
+CCTCGCTCATAAATTTCCATTTTTCTCTTTACAAACATTGATTGATTTCC
+TTATTCTATTGACTTTCTGATATTAAATTGATCATCTACTAAAAGGTATA
+TATATATATAAGGTATATCAACTCTTGGAGCCCATATCTTTAATGCTCAT
+CAAACTCCCAGTTAGGACTGGGAGTGAAGTACTGGGTGGTGGGATAAGAA
+AGTTAGGATGTGACGGGTTTCATGCTCATCTCGAGCTGCCAATCTTGCAC
+ATTAAGCAATTGGCTCATTGGCATGCTCTTGTCCTCTGGGCCTGCCGCGG
+AGCCATCTCCCGTTTGATATCTGCTCCCGGGGGACGTTCCCAACTTGGCC
+GGAGAGAGGCGCCGCGAGCAGCACAAGCTCAACCAAAACTTTTCTAATGT
+AATGGGCCGGAATTAGGGGAAGAACAAACGAAGGAGAGGGTGGGGTGGAT
+GAGGAAGAGAAAAGAGCACCACCACCAACTGATTTGATGGTTGGAGAGGA
+GCTCGTTTTGTTTTCTTGTCGTCGTAAGAAGAAGAAGAGAAGCGCGCTAG
+TTAGTGGTTAAACGAATCAAGACCCGAATGTGATAGATGTGCCGCCAATT
+TAGCCAGTAGGATTTTTGCTGATTTTGCACACATTCATTTTTCGCTTGCC
+TAGACATTACATCCCATCTTATTCCGCTTCATTCATTGTCGTGATTTTAA
+GATTTGGGGGACCTAGGAGCCTCTACAGTATTATTTAAATTTCACTTTTG
+TTTGGATTTTGAAAAGAGATGCGTCATACATATTCATTTTAAGGCACCTA
+TGTATACAGTTCAAAATTTTGGAACATTCCTGGAATAGCGATCTTAAAGC
+GGGAAATATAATGACATTATCTGACAATTTTTTCGAACACCTAAAAAACT
+TGAATAAAGCCAATTGAATCGTATCCCTAATGGTTTGCAAAGTTGGGCCA
+TGCTCTGAATAGCTTAGAGTTCCATCCTGACCTGGAGCTCGCCAGAAGCT
+GAACGCACTGAACTTCCAGTCAAGCCTCTTTTGAATAAGTCTAGTTGCAG
+ACTAGAAGCCTTAACTACCTGATGAGATTTTCACCCTTCTCTCATTAGTC
+TATTTCATTAAGCATGAACTTACACGAGAATTCCAATTACATTACCATGT
+AACATTACTTAAGATCCCATTTCCACTTAATTTGTGAAAATCGATACGGT
+TTTATAAGAAGTGTTTTGTCCTTTTGCCTATAGCCTAGAGCAAAAATACC
+CAAATTATTTGGCAGATCATGTCTCCGACAATATTCTGATCGATTAAGAA
+ACTTTTGCAAATCTGCTCGGTTTTTTAGTCTACATTCGCCCCCAGATAAC
+TGTTCTCGGCAAGTTGCCGATTTGCCGATTTGCCGGAAATTTTTCTTTTC
+GCCAACTTACTGATTTGCCGGAAATGTTTAAGGGATTTTTTTGAAGACGG
+AAAATTTTTTCATTAGATATGTTCATAGAATTAGCTTGCATTACAAAATA
+GGTGTATGAACATATTCAAAGGATGCGTACAATTTTGCCGATTGAAATTG
+AAATTCTGAAATTTCCAAAAATAAATGTGCAAAACCACAATTTGCCGTTT
+TCCGGCCAATTCGGCAAATCGGCAATTTTCTGGGTTGCAAATTTGCCGGA
+AATTTTCAATTCCCTTTATTTGCCGGGTTGCAAATTTGCCAGAAATTTTC
+AATTCCGCAAATTTGCCGTTTTTCCGGCCAATTCGGAAAATCGGCAATTT
+TCCGGGTTGCAAATTTGCCGGAAATTTTCAATTCCCTTTATTTGCCGGGT
+TGCAAATTTGCCAGAAATTTTCAATTCCGGCAATTTGTCAGTTTGCCATA
+AATTTTCAATTCCGGCAATTTGTCGATTTACCGGAAAAAATCGTTTGCAC
+CCACCCTTGATGTGAACGCTAGCACTACCTCCTAGTATTAAGGCTCCAGC
+TAATTTCTATATCATGGCTCCCAACTATACGTTCCTCCCTCCTCCCCCTT
+CCCAATTTCGAATGGGCGCCAATTATTGCTCAATTCCCATCAGATTGGGG
+GGGGGGGGGGGGGGGGCATTCGTACAGTGTCAACACGAATAATAATTATG
+AGCCCTCTTCTATGCCCAAAGCGCGGCGTCTTCTTCTTCACCCCTCTAGG
+AAGTTCTCATAATTAGCATTTTGTAAGACTCGGTGTCCCCCTTTCAAGTA
+TCTCTGGATGATTCCCCCCTCTCGCACACACTCTTCCCATTTTTTTTTCA
+CAATAATCATAATCATCAAGTTGGACACCAAAAAAGCCATAAATTCGATT
+CCGGTCGAATCGAGAGAATTGGAAGAGAGAGAGAGAGAGAGAGAGAAAGA
+GGAAATGAGACAGAGGGGTGAGAGATGGAAAACGAACAAGTGTGATGGTC
+GTCCCCCCCCCCCCCCCCCACGGGGCCGCTCCTCATTCCTATATTTATTT
+ACAGCTCTCTCTCTCTTTTTCTCTTCAATTTCCATCTCTCTCTCCTCATC
+TACAGTAATCGGGGAGGGGCTAGTGATAAGCCTCTCCCCGCCCCCCCCCC
+CCCGGCGGTTAGGTGTCAGAAATTAATCATAGAGGCCACGCCTCTAATGT
+TTTCGGAGCATCATCCTTAATTCTTTAATTCATTAACCTTAATTCATTAG
+TCTTACACTGAATTTCATAACTAAACTTGTTGAAAAAACTTCTCAAAAAA
+AAAAGTTTTGGCGGCTTAAGAAATGGCCTAAAATTAGTTCGACTTTTCAA
+GCGGCTGGAAACTAACTTTTTTTGAAATCCCCCCTAATTATGGGTCTACA
+ACGTAAATAAAAAAATTTGGTGACCAAATTTATTTAGGCCAAATCTGGTG
+TTCAAATTTTTTAGGCCAAATCTGGTGACTAAATTTTTTAGGGCCCAATA
+TGGTGAAAAAATTTTTTAAGGCCAAATCTGGTAACCACAATTTTTTAAGG
+CCAAACTTTTTAAAGACCAAATTTTTAGAGCCAAATCTGGTGACCAAATG
+TTTTTAGGGCCGAATCTAATGACCAAATTTTTTTAAGGCCAGACCTTTTA
+AAGCCCTAATTTTTTAGGGCCAAATCTGGTGACCAAATTTTTTAGGCCAA
+GTCTTGTGATCAATTTTTTAGGCCAAATCTGATGACCAAATTTTTTAGGC
+CAAATCTAATGACCAAATTTATTTAGGGGCCAAATCTGGTGACCAAATGT
+TTTTAGGGCCAAATCTGGTGACCAAAATTTTTTAAGGCCAAATCTAGTTA
+CCAAATTTTTTAAGGCCAAATCTGGACACCGAATTTTTTAGGCCAAGTCT
+TGTGATCAAATTTTTTTAAAAATTTTTTTCAAATCTGGTGACCAATGTTT
+TTTTAGGGCCAAATTTGGTGGCAAAATTTTTAAGGCCAAACTTTTAGGAC
+AAATCTGGTGACCAAATTTTTAAGGCCAGAATCCACAACTTTTTTTTGAG
+AAATTTTGAAGAAGTTTCTAATTCACCTAATTCATTACTCTTTTTGAATT
+TAATCTTCGATATTCCAGATTTCAAAACGATGGAGGATGCGGCGTACGCG
+TGTGCTGGCTGCGAATTCACCACAAGTGAGTTTTTTTTGTTGTTTCCTTA
+TCAGCATCAGCTCTATGCCTTCTCCCCACCCCACCCCGCTCCTCCTGTAA
+CCTTCAATTGCCATTCATTTCACACAGTAATAGTACCACACAACACCCTT
+CCATGCCTTCAATTTGACTCATTAATAGCCCTTTTCACCATGTCTTTTTT
+CCCCCTCTTTCTCTCTAATACTCAACCTTTACCTACCTACCCGCAATTTA
+ATTGGCAACTAATTCGGATACATTCGGACGGCTCAAACGATGCGCGTCCG
+TCGTCGGGTGCCCGAGACTGGGACCGGTTTTCAGAATGTCAGTGTATGTG
+TGTGTGTGTCTACCGGCTGGCAGGCAGCCACACCACTGCGATTCGTTAAT
+TTATTGTGAGATGATGACTGTACATTATTTTGAGTGCTGCTGGTGCTGGT
+GGTGTGCATCATATAATTATAGCCTAGTTGATAGAGATATATCGACACAC
+ACACACATACACATTTACTTTCAATTGCTTCTACCCAATCTTTTTTCTTC
+CATTCTCCAATTCCTCTCCTTGCTCCCATTTCGCCCTTTGATATTCACCG
+CGTTTCGCGTTTCGCACTAATTTCGCGCCCGGACCGGTGTGCTCGGCGCG
+GCACGTCTTTCATCTTTTTGCCTCAATTTCATTATGATAATAATAATCAT
+AATAATTATGCGAGACACGGCAAAGACGCGCTCAAGAAACTGATAAGTGT
+GTATAGGTCGGGTCCTTTTGAGAGAGAGAGAGAGCGAGGTGTGATAAGCG
+CGTCTAATGAGCATGGGCAATCATAACATTCCTATCAGCATATCAGCATT
+AAAACATTTTTTTCAGAAGACGTGTCGGACTTTGAAGAGCACGCAAAAGG
+ACACGAAGAGGAGGCGGGAGCCTCTTCACAGAAGGCGTGTGCGCTGTGCC
+TTGAGCCCACCGACGACCTCGAAAAGCACCTTGTCGAGCAGCATCGCATC
+GCCGAGAGCGCCATCGAAAAGTTCCTGCTTACTGAGAGAACAGCCAAGTG
+AGTGTTTTTTTTTGTCTTCAACTCAAATATCTAGTAGTAAGTCTTATACT
+TGGCTTATATTTCAGCGGTTTCAAAATATTTTTGATAGCTTTAAAAACCA
+TAGAATAACAATTAATTTGACAACAATTTTGTCGTTTGAATTTTTTGACA
+AAAATTTTGTCGTTTGAATTTTTAAAATATGATCAAAGACAACCGAGATA
+TAAACGGTCAAAGTCCAGTGAGAGGGGCCATACTAATAGGGATTATACGG
+TAGGTAACGAAATTTTGATAAGACTTATAAGGACAAAGATAATGGAGCTA
+GAAAGTTTAAACTAGTCCAATTTGAACAATAAAAATATATATAACGTACT
+TTTTAGTATAAATATTTTAAAAGTAGAGTAATCTGAGATACAGTAAATTT
+TTAACAATTTCTAGTCGATGCACCATGTGCAAAAACTAGTCCAGTCCTAA
+AATTAAATAGCACGTACTTTTTAGTATAGATATTTCAAAAGTTAAGCCAT
+CTGATATACAGTGAATTTTACCAATTCCTAGTCGATGCACCATGTGCCCA
+CTTAACTTTCACGGCTCACTTCCCGGCTAATTTCAAACATTTCAAAATAT
+TTTCAACTATTCAACTATAGAGGGGTTTTTAATAAACATTTTCTCAGTTG
+ACGACTTTTTTATAGAATCAAAGACTACCTAGATATAGCTAGTTAAAGTC
+GAGATGCAAGATTTTTCGGAAAAATCACGTGGTGTTTTCGGTTTGATCTA
+CGTAGATCAACGAAAAATGCGGGAGAAGAGACGCAGAGTTATCAACTGAT
+TTCGTATGGTTAAGAACGTGCTGACGATGTCACATATTTTTGAACAAAAA
+ATTCCCGCATTTTTTGTAGATCAAACCGTAATGGGGCAGCCTCGCACCAC
+GTGAAAAATTAGTTTTTGAGGCTTTTCTAGTCTAGAACTAAAGTTTTTTT
+TTTGATTGGCCTTGTTTTTTCTAGTCTTAAACACCAGGTAGATCAAAACA
+AATTTTTTTTCAGAGTTTCGATTTTTATGAATTTAAAACTTTCAAATTGT
+CGCACTTCCTGTCCCTTTCAACCCCAAAAACGTTACGATTTTGTGCTATC
+ATAATCATTAAACCATGCTTGCTTGTGTCAAGTTGCACAGGGTGCGCCGG
+GGGGGGAATTGGCATTACTGTAAATTTCCTGCGTCTCCATCCTTGCCCCC
+AGTGTCCCCATCGGCAATTAGAGAGTACGATCCGATTTTGCATATTTTAT
+TCACGTCGCCTCTTGTTTACTCGCTCTAAATTTCAATCCGTCGCCAACCC
+CCCCCCCCTGCCTGCCTCTTCCATTCATCATGAGTATTAGTGTATTGATT
+AATTTTCGAATTCACGAATGAATTCATTGCTGGCGCCCTGCTACTAGTAA
+TCAGTGAGGTCATAGCGTTGTCCTTTCGATAGGGCTAATTAAATGTTTCT
+CTAGGAGCGGGAGGATAGATTTGAAATCAGGTGGGCGTCGGTTTGATCTA
+CGTAGATCTACGAAAATCGCGGGAATTTAGACGCAGACTTCTCAACTGAT
+TTTGCATGGTTAAAAACGTGCTGACGTCATATTTTTAGGGGAAAATATCC
+CGCACTTTTTGTAGATCAAACCGTAATGGGACAGCCTGACACCATGTGCT
+CAGTTACAATTGGAGGGTTTTGTCGGAAAAAAATCAATTTTTTAAACTGA
+CAACACATTTTGCTCATTCTCCAAAACTGAGCCAAATGTGTTGTCAAACT
+TTTCTTGAAATTTTTTTGAATCGAAATTATGTTGAGGTGAATTTTCAAAT
+TTCAAAAAATGCCCCATTTCTATCAATTTGTCTTCACCTATGTTTTCGAA
+TAAGGGCGAGGCGAGAGGCAGGCGGAGGTCGCCTTAAGATCATAAGATAG
+CCTTATGTGATGACGAAAAATGCCAAAAAATGTATTTTTATATAGTTTCC
+CCGTGTGTAGAAAAATGTAAAAAGAGCATGCATTTTGTGCATTTTTTGAC
+ATTTTTCTGCATTTTTTTTTGACATTTTTTTTTCATTTTTCCACACAGAT
+GAATAGCGGAAAAACGGAAAAAAATACATTTTTGCATTTTTCATGATCAC
+ATGATCAACCCCATAAGGTTTTTTAAGGCATAATATTGATATTTTTTATT
+AGTCTACTTTGCATAATGCCTACTATTGAAGGCAAATCAAATCGACATCA
+CTTTTTGCTCATTTTCAAAACTGAGAGGCACGGCTTCTATGTTGACTACT
+AAACCAGTAATAACACTTATAAAATGTTTGGAAAACACTCATACACATTG
+CCACGTCATTTGGATGGAAGGGACCCCATTTGTTGAATCATAATTGATTG
+TTAAACTATCATCACTCTCCCCCCGCCCTCCTCATTGGACCCCACGGCTC
+CAAACTGTCTCCAATTTGCTCCCCGTCCTCTTCTTATCACCTTGACGCGT
+AATTGAATTTTTGCGGATTTCTTCCTCCCCACCGCTTCCTTTGCTCCTTG
+GGGGAAAAGTATGGAGAGTGTTTATGTGTGTGATTGAATTGAAGAAGGTG
+GCTGACTCATTCTTTCATTTTCCTCGCTTTCTTTGAAAGAACAACTTGAC
+AGTTTCCCCCCCCCCCCCCCATCTTATAATAATAATTACTTGCAGAGAAG
+CGTCGTGTTCATCGTCGTCGGAGCCGAGCTCAGAATTCGCGCATCGCTGC
+TCGAGGTGCTCGATGGCGTTCCGAAGCGAGTCGCAGCTGCAGACGCATTC
+CCTTCAGCACGTGTTCAACACGTTCCACAAGTGCCCCACGTGTGGCGATT
+CGTTTGATGAGAATACTATTGTGGTGAGTGAATTCACAACACTTTTGGCT
+CACAGTCACGCTTGATCTACGTGTTTTTAGACAATTTTGAGTCTACACGT
+GGTGTCAAAGTGTCTCATTTCGGCTTGATCTGCGTTGATCTACAGAAAAA
+TGCGGGAGAAGAGTTTTGGGCAAAAAATTCCCGCATTTTTTGTAGATCAA
+ACCGTAATGGGACAGCCTGGCACCACGTGCTCAGTTAAAGTAAGAGGGTT
+TTGTCACTAGATTTATTTTTTGTAAACTGACAACACATTTTGCTCATTCT
+CCAAAACTGAGCTAAAAGGGTTGTCAAACTTTTTTTGAAATTTTTTTAAA
+CGAAATTAGTTTTGCTAGTTTTCCTAAAAGGAGCAAAAAGTGTTGTCCAA
+TTTTTATAAGAAGGTTTTTGTCGCCTAATCGATTTTTGTAAACTGACAAC
+CCTTTTCGCTCTTTTTTCAAAATTAATTTTTTTCTTTTGGCATTAATCCC
+ATTTTTTGTAAATTAACAAAAAAATTTCAAAAAATCTTCAAGTATTTCTA
+CAGGGTGGCCTAGATTCTCTATAGGGTGGCCTACATTTTTACACTGGTTG
+TCTAGATTCTTAAACAGGGTGGCCTCGATTCTGTACAGGGTGGCCTAGAT
+TTTCTACACGGTGGTCTAGATTTTCACTGGTGGCCTAGATTCTCACACTA
+GGTGGCCTAGATTTTTCCACTAATAGCCTAGATTCTTTACAGGGTGTCCT
+AGATTTTCACACTGGTGTCCTAGATTCTACACAGGGTGACCTAGATTTTT
+TACACTGGTGGCCTAGATTCTCTACAGGGTGGCCTAAATTCCTTATAGGA
+TGACCTAGATTCTTAAACAGGATGACCTAGATCTTGACACTAGTGGCCTT
+GATTTTTTACAGGGTGGCCTAGATTTTCTACAATGGTCTAGATTTTTTGC
+AGGGTGGCTTGGATTCTTAAACAAGGTGGCCTAGATTTTTCACAGGGTGG
+CCTAGATTTTATACAGGGTGGTCTAGATTTTTACACTGGTGGCCTAGATT
+CTTTACAGGTTGGCCTAGATTTTCTATAGGATGGCCTAGATTCTTAAACA
+GGGTGGCCTAGATTCTTTACAGGGTAGCCTAGATTCTTCACAGGGTAGCC
+TAGATTTTTACACTGGTGGCCTAGATTTTCTAAAGGGTGGTCTAGATTTT
+TGCACTGGTGGCCTAGATTCTTAAACAGGCTGGCCTAAATTCCTTAGGGG
+ATGCCCTAAATTCTTAAACAGGATGACCTAGATTTTATACAGGATGGCCT
+AGAACTACTTTTTGTAAATCGACAGCACTTTTTGCTCGTTTTCCAAATCG
+TTTTTTTTTCAGACCCATATGTTGGAGCACACCAAAGAAGAATGCGAAAT
+GTGCTCTGAAACATTTGCCACAAAAGAGGCATTCCTCTCCCACCTGAACT
+CAGCCCGACACCTACAACAGGCAAAGAAGCAGCTGGAAAACTCACTGGTC
+GACTTAAACTCTCAGGTGAGCCGCCGCCGTGCCTCCTGCCGCCTGGCTAC
+CGTAATCACCGTACCCATTATTTAATTGATTTGCTTTTAGCCACGCCGCT
+GCTGCTCGGAGCGCAGAGGTGACAGAAAAAGCCGACAAAAAACAACATTA
+AAATTATTACACTTTTTTATGATTGAATGCGAGAGAGATGTATGTGTGTG
+GAGAGATGGAGAGGCGCATGAAATGGTGTTCGGGTTCCATAGCAAGCTCA
+TTGAGCACAATGATTTTTTTTTAAATATATTTTATTGGAAATGACAGAAG
+CTGAAGCTTGAAAGGAACGTCCAGTTTTAAATTAAAGTATTGATTTAGCA
+CGTAGTTTCAGCATGTCCCATCACGGTTTGATCTACAAAAAATGCGGGAA
+TTTTCTTCCCAAAAAATTTGACGTCAGAACGTTCTTAACCATGCGAAATA
+AATTGAGAACTCTGCGTCTCAACTCCCGCATTTTTTGTAGATCTACGTAG
+ATCAAACCGAAATGGGACACTTTGACACCATGTGATATTTAAAGGGTCTA
+GAAAGAACTTAAAATAGCCTAGCCAAGAAATGGGCGGAGCTTTGGTAGGA
+ATTTTCATAAGTCGAGGACTCCGCCCATTTCTTGGCCAATTTGGGTTTTT
+GGCCTTCAATTTTTAGTGTTCACTAATTTCCAATAAGTTTAGGATTGAAA
+AAGTTTTTGAGGTGAAAATTGATCCTAGCATAGGCTCCGCCCATTTCTTG
+GTTTTTTTTTTGTTTTTTTTTCTTTTAAACTAAAATTCCACTGAACTTGT
+CTAATTTCAGTTTCCAAAAATTTAACGAAAAAATTCGAAATGCCAAGAAA
+GGGGCGGAGCCTAAGCGAAGCCTATTTTTCGATGAAATTTGGCCAAGTTG
+CGATGTTTTTGAATTTCATATTTTTGAATCAAGTTTTGAAATAAAAAGTA
+ATATAAAATTGGAAAATAGGCTCCGCCCATTTATTGGCTTTGTTGGATTT
+TTTACTGCATAGATCACATTTTTGCATCCGAAAATTTATCGGAAAGGAAT
+TTTTTTTCCCAATTTTTTTCCGTAAACTGTATCATCAAATTCTTTTGAGA
+TTCAAAATATCCAACATAAGCACGGGGTTCTGGCCTTCCTCATTGAATTT
+TTCGCGCTCCATTGACAATCGCCTGCCGGACAACGCGTGGGAAAGTCGTG
+TACTCCACGCGGACAAATACATTCAGTTTTACGCGCCGTAAATCTACCCC
+AGATATGGCCGAGCCAAAATGGCCTAGTTCGGCAAACTCTTTCATTTCAA
+TTTATGAGGGAAGCCAGAACTCCGTACATAGGCGCAATAAAAGGTGAAAT
+AGGCTCCGCCCATATCTTGGATCGGTTCCAATAATGTATCCAAATTGACA
+TGTGTTAGTTACACTTGTTCCTAATCCAAAATTCTATCCGAATTTCAATT
+TCCCAAAGTCAAAAAGTCAACAAGTTCTGTTCTTATATGTGTAAGGCGCG
+CGCGAGCGCGATCGTTTGTCTCTAGTATTTGCTCATCTCTCTCTCTCTCA
+ATTACCGTACCCATTATCATTCCGCCCATGGATGATGATGATGATGAAAA
+TGAGCGGTGGGCCCCCTCTTCCCCTGCCTCTTTTCGCGCATTCATCATGT
+TTGTACAAAAGGCGGCGGTTTGAGAAAAGAAGACAGTGAGAGGGAGGGAG
+AGAGAGAGGTGATGAAGGTAGTAAACGTGTGTCGACAAACACATATAGAG
+AACGATTCGTGTGAAATAGATGAGGGCAAATAGGACGAATTTATTTAAGA
+GAAGAATAAGATGCTTTGGCCCAGATGAGGGGGGGGGGGGGGTATCATGA
+AGGTGTGATGACGAACCATATTCCTTCAATGTTTGTTGCTCGCTTAACCG
+CCGTCGCCGCAATTTAAATTGTTTCGACTGGGTGATCAGACAAATAAGAA
+GACGTAGACGGTTTTTCTTGGGGGGGACGTTCAGCTTTGATTCCTTTCAA
+ATAATCGATGCGGCCTAGCTTTCTGATCTCCAGAAACCGCGGGCCTTCTT
+TGCTAAATTTTAAGCGATTTTACTTCCTCCCCCCCCCACTTTGATCTACT
+TTAACAGCTTATATCTCGGTTGTCTTTAGCTTCATCAAAAAGTTATCAAC
+TAACAAAGTGCGTGCCAAATATACTTCTACAATTCGGTAGTTAGTATTTT
+TTGGATAAAAGTTAAGACAACCGAGATATAAGCTGTTGAAGTAAATTTCT
+AGTTTGACTTACTCCCCCAATTTTGATCTACTTTTACAGCTTATATCTCG
+GTTGTTTTTGGTAACAGCAAAAAGTTGCCAACTAACATATTACGTGCCAA
+ATATTTTTCTAAAATTTGGTAGTTGAAAATTTTTGAATAAAAGTTAAGAC
+AACCGAGATATAAGCTGTTGAAGTAGATTTCTAGTTTGACTTACTCCCCA
+AATTTCGATCTACTTTGACAGCTTATATCTCGGTTATTTTTGGCAATATT
+AAAAATTTGTCAACTAACAAATTACGACCCAAATATTTATCTACAATTTG
+GTAGTTGAACATTTATGTTAAAAGTTAATACAGCCGAGATATAAGCTGTT
+GAAGTAAAGCAGTGGTGGTGCTTAGCTCGACCTATATTTTTGAATTGCAT
+AACAGTTATAACTAACTTATTTTATGTGAAACCCTATTCTAGCTAGTTGA
+CTTACAAAATCTCCAGAAACTTTTGCCTGCCTACCACCTTTAGCAGCATA
+AGCGCCTATAGGCACACCTACTGCCTACACCTATGCCACCTACTGTACAC
+CTACTGCCCATACGCCTACTGCCTTTTGCCTACTTTCTACATAACTTTGA
+ACTGCCCGTTTCTAACCAATAATCTTTTACAGGACGTCGAAAAGCAGCGT
+ATTTATGTGTGCAACGTCTGCAAACAATCCTATCCACAAGCGGCTAATCT
+CGACGTGCACATGAGGTCAATGACACATCAGAGCCGGATGAGCCGGCTGT
+CCGAACTTGTGGCAACCGGGGAGCTTAATGGGGAGAAGGCCGTGTTTGAG
+CAACCAGGAATACCGGCACCGACGATAAACAGCTTCATTGAGACGGTAGG
+TGAGGGGTTTGAGCAGGCATAATCCTGAAAATCATCTGTTTGGTTTCTGT
+GAAAAACTTTTGTGCGGAAAATAGTTTATTTATAGTTCAATTTGAAAAAA
+ACTGGTTTCCGATTTTCAATTTTCAATTTTCAATGTTCGATTCTCGATTA
+ATAAAATTTCCAATTTCCAATTTCCAGACAACCAACCAATCCTCACTGAA
+CGACCTGATGTCACTGCTCACACGAAGCGAGTCGGATGAGATTCGAGAAG
+AAGTAAACGGCCTTCAAGTCATGACACAGATCAAAGTCTACGGTGAATCC
+AAGATCACTAGCCTAGTCCCAGAGTTGGCCGGGAAAATCGATAACATCGC
+GCTCTTCGATGACTCCCGTGCGGCAGAGGTGTCGAAGATCGATTGCTCGG
+CTTGTGGGCAGCAGATCTCAGGGATCCTTGCTTTGAACCTCCATTATGAA
+GAGTCCCACTCATCGAAGATCCCGAGTGACGTGTTAAGAAAGTTCGGAGA
+GCGGTTACTTGCCGCATTAGAGGACGGGTTGAGCAGAGAGAATTCCGTGA
+AGAACGGATCGCAAAGCCCTCTGAGCAATGACGATGAGCCCATGGAGAAG
+AAGATGCGGCTGGAGAATATGCTTCCTGAAATGGACAAGAACGCGGCAGC
+GTCGCAATTCGCAATGTTCCAACAAATGATGAACTGCTTCCCGTTCATGG
+CACCACCAGGCACGTCTAGTGGCAACTTTGGCTTCTCGCCAGAAATGATC
+AATCAGCTCATGAATCCTGCGGCGGCGGCGGCGGCGGCGACTGCAGCAGC
+AGCAGCCCACGCTGCCAACAACTCGCCGGCGAAGAGAGCAAGAACACGGA
+TCACTGATGATCAGCTCAAAGTTTTACGGTAAGTCGTCTTGTGTGTGATT
+ACTGTAAGCTACGGCGAACAGGAGAGACCCGAGGGGGGCGGTGGAAAATG
+AATTGCAAACAATAGGTGGGAAATGGTCGGCGCCGTGATCAAAATGAATG
+AGAAATGAGAATGAAGAACAAACATTGTGTGTGAGTGTGTGTGTGTGAGA
+CGAGACGAAAATCAATCAATTTCTGGAAAAAACAACACATATATTTTCCC
+GGCGAACTTTCTGTTTGAGGGACCGTACGGAACAGGACCCCCCTGAAAAA
+AAAAATCCGGAAAATCCTAAGCCTAAATAGCGAACGCTCGCCACTGACGC
+CAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCCAGCCCAAGCCTAA
+ACAGGAACCCCCTGAAAAATCAAAAAATCCGGAAAATCCTAAGCCTAAAT
+AGCGAACGCTCGCCACTGACGCCAAGCCTAAGTCTAAGCCTAAGCCTAAG
+CCTAAGCCCAGCCCAAGCCTAAACAGGAACCCCCTGAAAAATCAAAAAAT
+CCGGAAAATCCTAAGCCTAAATAGCGAACGCTCGCCACTGACGCCAAGCC
+TAAGCCTAAGCCTAAGCCTTGGCCTAAGCCCAGCCCAAACCTAAGCCCAA
+GCCTAAGCCTTTCACCTTCCTAATTTTCAGGCAGGCCCTAAAAACCGCGC
+CTGCCTACCATGGAAGCCCTAATCTGTGCGCTTTAGATTCTGAACCCTTA
+AATATGTTGCACGGCCGGGCAAAGGGCACATCAGTGTAAACGCGCTCTAC
+TGATAATTCGAGTTTAGCCAGGTTTGGGCGCGTTTCAAGGAAAAAAACTT
+TGGCTCAAAAAATTGTGAATTTATTTTCGAACATTTTTATATGCATCACA
+AAAATGTTAGACCACCCGTTTTTGAGAAAAACGCGCCCAAACGTCCAGGT
+ATACGGTAGACAAATTGCGTACAGGTACCACTGGGGGGTCGTGTTTGGGC
+TTTAGTTTAGCTAAGGGAATCTGTAGCGGCCCAACGGCCTAACTGCAAGC
+CTCAGCTTATTCGCCATAGGCTTGTCTGCCGTATTTCAAGCCGATTCCAA
+CAAAAAACTTCCAGCCAATACTTCAACATCAACAACTCGCCGTCAGAAGC
+GCAAATCAAGGAGATGTCACAAAAAGCGAGCCTTCCGGAGAAAGTCATCA
+AACACTGGTTCCGCAACACACTTTTCAAGGTTTGTTTATTTATTTTACAA
+AACTATTCATATTGTTATTAGGCTCGGAAATGAGCGAGGTGAGAACATGA
+GTGTGGTAATTAGTCATCGGATGAATACCCACACAAGAGGGAGAGCAAAC
+AAGAGAGCAATTGAGACGAGGGAGGGAGAGAGGGAGAAAATAAGAAAATG
+TTAATGTCAGTTGGGTGCCAGGCGCTCGGCCAGGACCACAGGCCGGGAAC
+CATTTAGTTTTGATTACGATTTCCGTCGTGACTCATGATGGGAATTGATA
+TTTGTGCCTGTGGTGATAGAATAGTTAGAGCAACTATCAGGAAGGGGACA
+AGTCGCAGTGCGAGACTATTAGAACCTGCAAGGTTTATTCTGATAGATTT
+GGGACTAATAAGGACTAATTTGGTAGAGACTAATTGGCTCTCTTGATATA
+TACCAGCTTAATAATTTCTACAAAAAAAACTGTAAGAACGCTTCGAGATT
+CGAGCTTCGGGAAAGCTTAAAGGATGGGTACCGAAAAATTTTTTTTCCCT
+GATTCCGAATATCGATGTGGAAAAATTCAAAAAAAATTCCCTGATTTTAT
+ATTTGAGCTTGAAATCACGATTTTCATTTGTGCCCACCTGGTGTCAGAAT
+GTCTCATTTTGGATTGATCTACGTTGATCTACAAAAAATGCGGGAGAAGA
+GACGCAGAGTTCTCAACTGATTTTGCATGGTTAAGAACGTGCTGACGTCA
+CACTTTTTTGGGCAAAAGCAAAAAATTCCCGCATTTTTTGTAGATCAGAC
+TGTAATGAGACAGCCAGGCACCATGTGTGTGCCCCGGTTCAATTTTCAAT
+TTTTTAAACCAGTTTCTTTTTTTTTAGTCGATAGGTTTTTTTCTGAAAAA
+TATTTTTTTTGCCAAAAATGAATGTAACTGGCTAAAATAAACTAAAAATA
+AAACGATGCAAGCGCGCTCAAATGCGAATTTATTTGGGCGCGAATTTGAA
+AAAAGTGATGCGGGCACAAATGAAAATCGGCGATTTTAAGCCTAAATATA
+AAATCAGGGAAATTTTTTTGAATTTTTTCACATTGATATTCGTAATCAGG
+GGAGAATTTAAAGCCAATTAAAAATATTTTCCAGATTTCGGTGCCCCACC
+CTTAATGAGATAAAAGAGCAAAAAAGGTGTTTTGTAACTTTTTAAGTTTT
+TTCTTTTTCAGGAACGCCAACGCGACAAGGATTCCCCGTACAACTTCAGC
+ATCCCTCCCCAAATGGGAATCGACTTGGACATCTACGAAAAGACCGGCGA
+GACAAAAGTACTGTCGCTTAGCAATGAAGCACCAAAGTCTGAGTTGAGCT
+CTGCGCGCGCCACACCGACAATTCCGACTCCGATACCGCTCATCGTTGAA
+GAGAAGAAACCGGAGCCAAAGAGCCAGACACCATCGTCTTCTTCCTCTCA
+GCTCAACCTGCAGGCTATGTTATCTCAGATGCAGGGAAGTTTTTTCGACG
+CGTCAAACTTCATGTCAGCATCAGTGAATCCGATGACACCGAGCACTCCT
+TCCTGCAACACGTCGTCCAGTGGACGACGAGCCAATCGCACGAGATTCAC
+AGATTTCCAGCTGAGAACTCTACAGCAATTTTTCGACAAGCAAGCCTACC
+CGAAGGATGATGATCTTGAAGCGCTGAGCAAGAAGCTTCAGCTGAGTCCA
+CGTGTGATTGTCGTCTGGTTCCAGAATGCACGGCAGAAGGCCAGAAAGAT
+CTATGAGAATCAGCCGAATCACGAGAGTTCCGATCGATTTGTGAGAACGC
+CGGGATCGAACTTTCAGTGCAAAAGGTTGGTTTTAGTGTTGGAAATTAAC
+ATTTAAATTTAAATTTTCCTAAATTCCAGGTGCAGCCAAGTATTCCAACG
+CTACTATGAACTCATCCAACATCAACAGAAAAAGTGCTACAAAGACGATG
+TAGCAGCCCTGGCAAGTGACAACAAGAGTGTCGAAGAATCACTGACGGAA
+GAAGAGAAATCCCAGCTTCTGGCTCAACAACAGGTCGCCCAACTAGCCAG
+CACTCTGGAGCTCCCAAAGTTCCAGCCGGCAGAGCTTTTGAAAATGATCG
+GAGCTAATTCGGTGACTCCATCCTCGTCGGCTGCAAGTCAGAAGTCTAGC
+AACGACGTTCTGCTGAAGATGTGTGAATCGATTGTTGGTGGGAGCACACC
+TAGTACATCATCGTTCCACAAACTTTGTATATTCTGCGCTCAAGACTTCA
+AGGATCGGAGTGCGATGAGTGAGCACATGGCTCAGAAGCATCCCCAGCAT
+ATGCTTCTTCCAAACTTCGATCTCGACATGATGCCAGACGCTGGTGGTGC
+AGAGCTTCTCATGGATCTTAAGGACTCTGCGTTGGATCTTTCGGGCTCTT
+CAGTCGACTACCGGGATTCTATCTCAACATCTCCATCTCGATCCGAAGAT
+GATGTTCTCACAGAGGCTCTGGATGATTCTGCATTTGCCGCGTTCGGACT
+ACAGCTTGCAAATTCCACAAGCGGCTCGGAATGCAGATCTCCGGCGAGCA
+ACAAGAGATTCCGAACTCATCTCACACCGATGCAAGTGCAAATGATGAAG
+AGCGTGTTCAACGAGTACAAGACCCCATCCATGGCAGAATGTGAGCTTCT
+CGGCAAGGAAGTCGGCCTTCACAAGCGTGTCGTTCAAGTCTGGTTTCAAA
+ATGCGCGAGCCAAAGAGCGAAAGACGCGCGGTGCAGTTGACGAGGACTCT
+CGATCCGGAGAACTTCACTGTGAAATTTGTGATAAGACGTTCGCGACGAG
+GCTTTCGCTGCAAGACCATCTGTTTGCCGAGCAGCACATTGAATTTTTAA
+GGAATAATCTGAAACGGGAAGGGGTCTCCGAGTTGACGACCGCTTCGGTG
+ACCGAGTGCTCTCCAGAGAAAAAGTAAGAAATTTAATTTTTAATTTAATT
+TTACATATATCATTACCCTATATAACCTTAAAAATTTTCCAGAGCAAAGC
+TTCCGAACCCGCTGGATCTTGCCAGTTTCCCGTTCCTCAACACGTTCGAC
+ATTCAAATTTACGGAACACCCATCGCCTTTCTGCAGGTGCCTGATGAGAT
+CAAAAAGCAGATCACTGATGATATCACGGCTGGAAAATCGCGAACCACGT
+TCTCCCAGGACGGTTTTCCGCTCGACAAGTTGAAAGAGTCGCTGCCCGAG
+GATGAGAAATCAAATTTGACAGTAACCCAGAAAGATGTGAGCTTTTTTTT
+TTTGGGAAAAATTTTGAACAATTTGGCAATTTCAGGTCGGATGGGCGTGC
+CCGGCATGTACATTTGTCTTCCAAGAAGAAAAGAAGCTCCGTGAGCATCA
+AAAAGCCATGTGCCAAAGTGATAAGGTGGGCAAGAAATTAGGAAACGGGC
+TTGAAGTTTAGCTTATAGTTAGGCAAGTGGTGTCAGACTGTCTTTGATCT
+ACAAAACATGCGGGAATTGGAATTTTTCCCAGAAAAATTGTGAAGTCAGC
+ACGTTTTTAACCATGCAAAATCAGTTGAGATGTCTGCGTCATTTCTCCCG
+CATTTTTTGTAGATCTACGTAGATCAAACCGAAATGAGGCACTTTCTGAA
+TCCACGAGCTAGGCTTAAGCTTAGGCTTAAGCTTAGGCCTTTTCTCAGGC
+TTAGGCTTAGGCTTATGCTCAGGCTTAGGCCTTTTCTTAGGCTTATGCTT
+GGGCTTAGGCTTAGGCGTAGGCTTAGGCTTAGGCTTAGGCTTATGCTTAG
+ACTTAGTCTCACTATCAGTCTTAGGCTTAGGCTTAGACTTAGGCTTAAGC
+TTAGGCTTAAGCTTAGACTTAGGCTTAGGCTTAGGCTTAGGCTTAGGCTT
+AGGTTTGGGCTTAGGCTTAGGCTTAACCTCAGGCTTAGGCTTAGGTTTAG
+GCTCAGGCTTAAACTTAGGCTTAGGCCCAGGCTTAGGCTTAGGCTCACAC
+GTTCTCACGTTCTTAACCATACAAAATCAGCTAAGAACTCTGCGTCTTTT
+CTCCCGCATTTTTTGTAGATCTACGTAGATCAAACCGAAATGAGGCACTT
+TCTGAATCCACGAGCTAGGCTTAAGCTTAGGCTTAAGCTTAGGCCTTTTC
+TCAGGCTTAGGCTTAGGCTTATGCCCAGGCTTAGGCCTTTTCTTAGGCTT
+ATGCTTGGGCTTAGGCTTAGGCGTAGGCTTAGGCTTAGGCTTAGGCTTAT
+GCTTAGACTTAGTCTCACTATCAGTCTTAGGCTTAGGCTTAGACTTAGGC
+TTAAGCTTAGGCTTAAGCTTAGACTTAGGCTTAGGCTTAGGCTTAGGCTT
+AGGCTTAGGTTTGGGCTTAGGCTTAGGCTTAACCTCAGGCTTAGGCTTAG
+GTTTAGGCTCAGGCTTAAACTTAGGCTTAGGCCCAGGCTTAGGCTTAGGC
+TCACACGTTCTCACGTTCTTAACCATACAAAATCAGCTAAGAACTCTGCG
+TCTTTTCTCTCGCATTTTTTGTAGATCAACGAAGATCGAGCCGAAATGAG
+GCACTCTGACATCACGTGGGCTAAGACTTAGGCTTAGGCTTAGGCTTAGG
+CTTAGGCTTAGGCTTAGACGTAGGCTTAGGCTAGTTATTTGTAACTTTTT
+TAAATCTCCCCCGAGTCAAAAAAAAAAACAATTCAATTCCAGACGCTAAC
+CCTGGTGCAAACCCACTACTCGTGCAAAAGCTGTCAAAGTGATTTCTGTC
+TTCAATCCGAGTATCAATTCCATCTCTCAATGCCTCCTCATACTACTACT
+ACTACCACGACGACGCCATAACAAAACCCCCCAAATAGTCACCTCATGTC
+ATTTCATTTGCCGTCTTCACTCAAGGACCTATTTCCGTCTCTCTCTCTCT
+CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTTCTCCTCTCG
+CCTTAAAAAAACCACAACTCCTTATCCCGATCTGAGCTCACTTCCTATCC
+CCCAAAGTAATTTCTTTGTAATATCTATATCCACTTTTTTTTCGACACAC
+TACACCACATCCCGCCGCCTATCCCCTCCCCCCCCACCGCTTTATGACAC
+AAAAACTGGTTTCGCTTTTGTCTTCAATTTCACCCCAACCGCCTGCAGCT
+TCTCATAATAATTAATAATTTTTCTTACCATGCACAATGATTTTGATAAA
+TATATATATATATAGTCATCAGGATTGCCCCCTTTCTAGGATATGTTTTT
+TTTTGTCTTCACACAATTTTCCCATTTTCTATGATAAGAATTATTTCTTT
+GTCCGGTTGACACATGTAGATGTTCCCCTTCCAATTTTTAATAGATTTCT
+ATTCTAGTTTTTTGCAGGCCTCACTATTCTATTGCAATAATCACTTGGAT
+TTCATGTATGGAACGCAATAATAATTCAATAAAATATTGGTACTTCTTTT
+TTGAAACACACTAATTCAAACTCACGCGGTTCCAGGCTGTCCCATTACGG
+TTTGATCTACTAAAAATGCGGGAATGTTTACTCCCAACAAAATGTGACAT
+CATCAGCACGTTTTTAACCATGCGATATCGGTTGAGTACTCTGCGTCTCT
+TCTCCCGCATTTTTTGTAGATCAAGCCAAAATGAGACACTATGACACCAC
+GTGTAGACTTAAAATTGACTGAAACCACCGAATTTCATATTGAAACTTCT
+TGAAATCTATTCAAAAAAAAAGTTATGAAGGCTCAAAAAATGGCCTAAAA
+TTTGTTAATTTAAACAAAAGACACTTAAAACGGTGTCTTTTTGAATTTTT
+CCGTTTTTTTAAACATATTTTCATAAAATTTACTTATTTTTCAAAATAGA
+TGTTGGAACATTTATAGGATGCGTTCAATTTTGCCATTTGAAATTGAAAT
+TCGGAAATTTCAAAAAAAAAAAAAAAAAGTGCGAAACCAAAATTTTCCGA
+AAATTTTCGGCAATTTGCCGGTTTGCCGGAAATTTCAATTCCAGCGATTT
+GCCAATTTGCCGAATGGCCGGAAATTTCAATTCCAGCAATTTGGCGATTT
+GCCGATTTGCCGGAACCTGCTAACCTACCTACTAACTTGCTAATCTTCAA
+GGTTTTTAATGAGTTTTCAATAGAAAATTCGGTGTTTTCAGGCAATTTCG
+AGAAAGCAATACAAACGTTTAACAAAAAAAAGACGCTTTTTCCTCTTATC
+CGATTCTCAATTCTCAATTTTGCCTTATCAATTTATCCTCTCCTCACAAG
+GTGACACACACACACACACACACACACACACTCGTTTCTCGACAAAAAGC
+TATGAGCTAACAAGCGCCTTCTCGCGTAAGAATACATCCACTGATAAGAC
+ATCTGATAAGAGTGGAACCCGTCCGCCATTGTCTCGAGAAATACACGCCT
+CCGCCCGGGAGGACAGGTTATCCCACCTCGTCGCTTCACTTCATTGTTTC
+AAACGATTCCATCGGCTTGCGCTTGGATTTTCTCTTATGCAACTTGCCAT
+TCTTCTTTTATTGCTTAACATCATGGTTATTTATTAGGGAAATTGTTCTA
+CCCTGACTTGAAATGACTGAAGACGGCCTATTTTACTTTAATTTGAAGAC
+TCAGAAGACTACTATAAGCGGTCATTCTTGTTGCGAAAATTTCTGCATTT
+AAAGGTGGAGTAGCGCCAGTGGGAAAATTGCTTTAAAACACGCCTATGAT
+ACCACAATGACCGAATATCATGATAAAAAAATTCAAAAAAATTTTCTAAA
+TTTTATATGATTTTTTGAAAATTGAAAAAATCTAAGGTTTTCACTTAATT
+CATATTTGAATTACCGCCAATTGGATTTGCTCGATGGAGCGCACTTGCAC
+GTTTTTAAATTTATTTATTTTATTTTTTGTTATTTTCCACCGATTTTTAA
+TGTTTTCGGTGTATTTTTGCTTGAATTTTAGAGAAAAAGTCAAAATAAAT
+GCAAATTTTCGATTAAAAAGCAAGCGTACAGGTAAATCAGTGAAATTAAT
+CAATTCAGGTTCATTTTTACGCCTGTAAGCGTGCTTTTTAATCGAAAATT
+TGCATAAAAAACATTTAAAATGGGTGGAAAATAACAAAACATAAAATAAA
+TAAACTTAAAAACGTGCAAGCGCGCTCCATCGAACAAATCCAATTGGCGG
+TAATTCAAATAGGAATTAGGCAAAAACTGAGATTCTTTCAATTTTCAAAA
+AATCATATAAAATTTAGAAAATTTTTTTGAATTTTTTATGGTGCGTCCAT
+AGAAAAACCGGAGTTCCTCGCTTTTTTTTCCTCGAAATTCAAAAAAGTAG
+GCGTGGCCAACCAATCAGCTGTTGTTTCTTGTTTTCTCATTGCTCAGCTT
+AAAATTTTACAGCCTCTAATTGGTTGAACACGCCCACTATTTTGAAATTG
+ACCAATAACAAAGCGAGAAACTTCTTGTTTTTTCCGCAGACTATGGACGC
+TTCCGCACGCGGGAAATTCCCGTTTTCCGCAGACTATGGACGCACCATTA
+TCATGATATTGGGTCATTGTGGTACCATAGGCATGTTTTAAAGCAATTTC
+CCCACTGGCGCTACTCCACCTTTAATGCATTCTGCGTCTATTTTATACAG
+TTCTGACCATAAAAGCACACAAATTTTTGTCTCAAAGTTTAGGAATATAT
+AGATTTAAGGAAGAAAGTTTTAGTAAGAAAAAATATAGTCTTCTTCATGT
+TTTCTTTTTTTTTACAATATCCATTTGCCATCCGTTTTTTTTTCTGCAAC
+CTTCGATAAATGTTTGCTTGGATAACTATGTAAGGTGCTTTGAACACTCG
+GCATTTGGGCTTCTTGCCCAAGTTTAGCCCAAAAATATTAACTTGGATCA
+GAAGTTGGGCAATACTTTGGCAAAACTTGGATTCAGGCAATATCAAAGTT
+TAACCCAAGTTTCACCCAACAAACTTTGGCCTAAACTTTTTTTGTTTCGA
+ACTTGCGTAGAAGTTTTTGCCCAATTTTCGCCCAACTTTTGCCCAACTTT
+TGCCCAAGTTTAGCCAACTTCTGTTCCAAGTTAATATTTTTGGGCCAAAC
+TTGGGCATGAAGCTAGAGCCGAATGCCGAGCTAATTTTATTTGACTCTAT
+CCGAATTCTGCTAATTCTCAAAAATCCCCCAATTGCCAACCATTTCAGAA
+TGCATTGGAGTAGTTGGGCGATAGCGCTCAACGTGCTCGTGCTGGCTTTG
+GCCGACAGTGCTCCTGAAAGATTCCCAGAGGATCATGTGGACCTGGTACT
+TCCTATGAAAAGTATCCACCATTTCACCTAAACGTTTCCTAATCATCTTG
+ATTACAGTGAAATACGACAGTCATCTTCGACAAGCTGATCTTCCACCGCA
+CTTCATTGGTGCCAATGAGACGAACTTGGTTCCGCTCACCTTGAGATTGG
+AGACTAGGAGGAAGAGATGCTCGTGTGGATGTTCGGGATGTGATCTTTTC
+CCGAATAGATCTTGTTGTTCGAGCTGTAAGTTTGCGATTCTATAAGACTT
+GTCAACGTGGTGTCAGGCTGACCCATTACGGTTTGATCTATAAAAAATGC
+GGGAAGTTTATGACCAGAAAAAAATGACGTCATCACATTCTTAACCATAC
+GAAATCAGTTGAGAAATCTGCGTCTCCCATTTCTTCTCCCGCATTTTTTG
+TAGATCTACGTAGATCAAGCCGAAATGAGACAATTGAAATTCCAGCTTGC
+TGCTCCTCTCAAAAACCAATCCCACTTGCCTGCTGTCCGCCACCTCCCCC
+ACCAAAACCGTGTTGCCAGCCAGCCTTCGGCCCTTGCTGCCCGGCAACCC
+CAAACTGTTGCCCGAAACCCTGCTGCCGAGGTCGTCGCCCCGAATACGAA
+GAGTACGAGGACGAGGAAGGCAACCCTGGAGGCGTCCCAGCACCACCAAA
+CCCACCAAGAACTTGCTGTCCTCCACCAACACCTGCTGCTCCACCACCGC
+CACCACCTCCACCACCACCGGCTCCGGAAGCTCCAACGCAATGCTGTGGA
+TCACAGCCTTATGGAAGAACACCGTGCAGGTCCGGATGTCCGAATGGAGA
+TTGTGGATGCGGAAGACCTTGCTGTTACTATCAGAACCCCACATGTTGTA
+ATCAAGGGCAAAAGGCTTGCTGCCCACCTGAACAGCCTTGCTGTCCTGAG
+TTGAAGCTGGATAACTGCCTCGCTTCGGTCCCACCTTGCCTTCGCGCCTG
+TCCATCGTGCCCTTGCAGAAAACGTCTGATGCTTGGGAAGAGAACTAAGA
+GAGACGCACCGGGGCTTCATTGCCAGCCAAGTAAGCTATAAGTTTAGATT
+TTCACGTAGTGTCAGGCTGTCTCATAGTGGTTTGATCTACAAAAAATGCG
+GGAATTTCTCGCCCAGGAAAATGTAACGTCAGCATCAGGGCTGGGACCAA
+AAAAAAAATTTTTGGACCAAAGAAGTTTTTGAAAAACCAAAAAAACCAAA
+AAAAAAACAAAAAAAAAACCAAAAAATTTTTGATATGCTTAAGTTGATTT
+TTAATGGGGTTATTCAAGTAATGTTGCAAAATGTATTAAAATACATTTAT
+GACGTCACAACTGTGTTAAAATACATGTTTTAATGTATTTTAATACAGAA
+TAGTCTCGAGTCGACACTAGACACGGTAAACTTTTTTTTTAGATTTTTCG
+TCAAAATACCAAAAAAACCAAAAAATTCCCAACAGCATGTTCTTAACCAT
+GCGAAATCAGTTGAAAAGTCTGCGTCTTTTCTCCCGCATTTTTCGAAGAT
+CAAACCAAAATGAGACACTTTGACACCACGTGGATTTTCAAAACGCTGAA
+AATAAGTAAAATAAATAAAAAATTTTCAGTCGGACTCCTTGGTCAACAAT
+CCCCACCGACTCTGATTTCAAAGCCGGTAAAGACCATAATAAAATCAAAA
+TCCCGCGTTGCTGGAACCAAGACATCTCAAGTGTCCGTCACCAAAAAGCT
+CATCGAACAATCCTCTGACCACGTGGAATCGCCTCCAACAGCCGGAAGAC
+TCTACGACTTCCGAAGAGCCCACGTTCGAGTCAAGAGAAACATGAACTTT
+GGAAATGGAGCATGCCAGCTGTGTCTGAACGGAACTCCGCTCAAGAGAAC
+CAAGCGGTCTCTCGATTGTGTTCCGTGTACCTACCTACAACCACAATACT
+CTGATTGGAACCCGTTCCTCGGAGATCAAACGCCACGCGGATCGCAGTCG
+CCAGTTGGAACTCCACTCGCCGGGCACAGAACTAAGAGAGCTGGCGTGAG
+TTTGACTCATAGAAATTAACGAAGCTAAATTTATTTTTGCAGTGCCTTCC
+TCATCCACAATGTACCCTGCATGTCCGTCGCTATAAGAGAAACCTGATCG
+GATCCCAATATTGTGAGCCATGCAATGGACACTACGGTAGAAAGAAGCGG
+GAAGCCGAGAGAGATCAGTGCTTGAAAAGAGAGAAAAGATATGCAGATGA
+ACAGTGTGATAACGATGAGTTCAGTATCAATGAGCGAAGCAAACGACAAG
+CCTACAATCCAAAAGGAATTTTGGATATCGTGAAGCTCCTATCCAAGGCC
+TCCTCAGGTGGCAACAATCCAGGAGGATGCATGAAGTTCCCAGCCTGTGT
+TCTGGCTCAGAAGAAGAGAAGAAAGAGAAATGCAGATCGGCTCGACACGT
+ACTACAAAGCTGTGGAGGAGCACAAGAAGCTGGTGGAAGAGTACGAGATG
+GCGATGGAGGAGCACAAGAGAGTCAAGCGGCAGTTCTTCGCTCCGGATAA
+TGCTGCATCCTGTGTTCCGTGTCCGGCATGGGTGACACTTGCCTTGGCTA
+GCAGAAAGAAGAGAGAAGTCGAGAAGGTGGAGAAGCATATGACGATGAGC
+GAAGCTATCGCGGATATCAGAGCAAAGAAGGGGTATAAGGAAGGATTTGA
+TGATGATGATGAGGTGAGGACTAGACCTGAAATTTTAGATCCTGTAAGAA
+CTTTTTGAAAATTCCAAAAAAAAAACCCCCTAATTGAATCACGCGCGCAC
+GCGCCACTGAGAAGGATACTGTATTCGCGGCGAGACCACCTGCACATCTA
+ACTCCCAAAAGTGACGAATTTGGCCTAAAATGGACTTTCTTCATGGGATT
+TCCACAGTTTTCACCATTTTTTTGACACAGTTCATGACTTTTTACACTCA
+AAAAATTATTGGCGTGGTCATTTCACAATGATTTCAACAATTTACTGGAT
+TTTACGCGTGTACTTCATCGTGGCACACCAAAAATTGATCTGGTTCATGT
+GGTGTCAGAGTGTCCCATTTTGGTTTGATCTACGTAGATCTACAAAAAAT
+GCGGGAGTTGAGAGACGCAGAGATCTCAACTGGCGTCACATCAATGCGGA
+TTTTAAAATTTTCATTTCAGGACGACGAATCCTCTGAGGAAACCATCGAG
+ACCCGCAGAAAGCAACGCCGCTCCTGCCAACAAAGTGACGATTGCCTGAA
+CAACGTCGAGTACGCAGTCTTCCAAAAAGTCTATGCAGACAAGAGAACCA
+AACGAGAAGCCGTGTTCCGTCGTAAGAAGTGCTCGAGGTGTGGAGTCTCT
+GGGCTCACGCCACATCGTGTCAAGAGAAACTTCGGGCAGCCGAATATCAA
+CGTCTCGGAGCAGAATTGCATGGCATTCCCACAGTGTCGGCATAGAGTGA
+AGAGAAACTTTTTGGGAGAAGACTGTAACATCTGTACACAGGATACTGGT
+CTGAAGCGGAGGAAGAGAGACTTCGGAACAGCGGTAGGTGTTGGTTTAAT
+GAGCTTCCTTATCTTAAAGTTTTCAGCAATGCTACCCATGCCCAGGAACA
+CGTTCATAACTTGAAGCGACTCCCTCCGATTCTCACATATCACATAAATA
+CCACCTCGTAATAATAATTCAACATGACTAATAAAACAAATAAGTACATA
+CATACATTTATATTAGCTTTTAGCACCCGTAGCAATTTGGAGCAAGAAAA
+TATGTGTAAAGAAATTGGAGATGTAGTAGATTTGGTCGTTATAGTGATCG
+CAGATCTTTCAGCTCTTTGAGCCGGAATATTGACTGGCTTGGAGCCAGGA
+GATGAACCTCGCGGGGGAATGAGGCAAAGTAGGGGTGAAGCATTGCACTG
+GCTGCGGAGACACGGCTTTCCGGGCGGAGCTGTAATTTTGAGGGTTACAA
+GATAGGTGTAGCTCGATGTCGATTCATTTAGACTAGCATTGCAGCCAGGG
+CTTAAGCTTTCGGCTTGAGCTTGCACTCAAAGATTGCTGCTCAATATAGC
+TCGCGAAGACTGATTTGTCAAAGATTAGACTAGTAGGCCTGGACTGACTT
+AAAGGTGGAGTAGCGCCAGTGAAAATTTTGTCAAAATACATACATAATGA
+TCCGAAAAAAAAACCAAATTTCATAATAAAACAATCCAAAAAATTAGATT
+TTTCACAATTTCAGGTCAAATTTTTGGCAAACTGCTAAAATTTTGAAAAA
+TGAGCAATTGAGGAAATCTAGAGCAATGTCGCATGTTCCGACCCCTACAA
+TATTTTAATACAAATAATTAAAACACAATTACAGTATAAAAATGTAGGAA
+AAAAAATTTTTTTTTTGTTGGTCGACTTCCAAAATTATGAGTGGTAAAAT
+TACAGTAAATAAAAAATTTTCAAAATTTTTTTGAAACGTTTTATTATGAT
+ATTCGGTCTTTTCGGGACTAAAGGAGTGGTTTTTACAAGTCTACTTACCT
+GAAGAAGCATCCCCAGAAGTTCCTGACCAGTCTTCAGAATCTTCGTGAAC
+ATCGGGTTCACCGCGATGAACGACAACTCCCGATACCTGGGGAACAGTTC
+AGGGGTGTAGCCTGGTAATGTCTTTACCTGAAACAAACATCTTTATCTCT
+AGATTTTAGATTCCCTCACCTCCGGCCACTTTTTCTCGTCTGGAGTACCC
+CGAATGCTGAAGATCATATCCAACTGGTCCTTGGTGCCGGGGTAGTGAGA
+GTCCTTGGATCCCGGGAACAAAGCGGCGCCCGTGCAAATTTCAGCGAATA
+TGCAACCGACTCCCCTGCAAAGTTAGTAGATATAGTTGGTACCTTTTATA
+AAATAATATCCTCCTACCACATATCCAGGGAAGTTGAATAGTCGGTACTT
+CCCATGAGAACATCAGGCGGGCGGTACCATAAAGTGACCACCTCGTGAGA
+ATATGTCCTACTCGGCACAGATTTCGCCCTGGCTAGACCAAAGTCTGCGA
+GTTTTAAAACACCGTCTTCGTCGAGAAGCAAGTTTTGTGGTTTTAAATCT
+CTGAAAATCAGTTTTTATCAAGAGTTATGGCCGCAACGGCGCCTCCGCCG
+ACCCCAGCGGTCGCCGCGCCGGCCTCCGCGGAACCCCGAAAATGTCCGCC
+GCTCCAAACAACCACTTTTTTGCACTACGTTGCGCACACACCAGGCTACT
+CATTTCACGCCAAGCTGCGGAACACCGAACGTGTCCGCCGCTCCAAATAA
+CTCCCTTTCGCAATACGTTGAGCACACACCAAGCTGCGGAACTCCCAACG
+TGTCGGCCGCTCCGAACAACCACTTCTACGCACTTCATTGCGCACACACC
+AGGTTACTCATTTCACGCCAAGCTGCGGAACCCTGAACGTGTCCGCCGCT
+CCAAACAACTCCCTTTCGCAATACGTTGAGCACACACCAAGCTGCGGAAC
+CCCCAACGTGTCGGCCGCTCCGAACAACCACTTCTACGCACTTCATTGCG
+CACACACCAGGCTACTCATTTCACGCCAAGCTGCGGAACCCCGAACGTGT
+CGGCCGCTCCAAATGACCACCTTTCGCGCTTCAACGGCGTCGGCGTGAGG
+CCCGAATTTCGCGCCTCACTCTGCTGGGAGCCCTATCAACACTAGGGAGC
+AGTTTGAAAACTAACCTATGAAGAATCTTCTTCCTATGACAAAAATCGAG
+TCCGCGGAGAAGTTGAAAGAGGAGAAGCTTGATGTCAATGCTATCCAACC
+CATAGACGTTCTGCTCCAGGTACTTGCTCAAATCCATTTTCATGTACTCG
+AACACAAAAGTTAGCTGGTGGTGTTGATAGAAGATGTCGTGCAAAGAGAC
+GATATTCGCATGACGGAGGTTTCTGAGAAGCGAGGCTTCACGGATAGCGG
+TGAATGGGAGACCTTCTTGAAATTGAAGTTTGATCTCTTTCAAGGCGACT
+ATGGATCCGTCAAGTCTGAAAATATAATTTAGTTTGGTAATATCAGCTGT
+TAAAATATCTAACTTCGATTCGCACTTATACACCGTTGCATAAGATCCTT
+CCCCCAGCTTGTCAATTCGTTTGTACAGATCATTCACATCCTGCGGTGTC
+ACTTCCTCCTTCGCAGGAAGCGTTATCGTATTTGGATCGTAGTGTGCTGA
+TCGTGGTCGACGTCTTCGAAGATGTGTGAAGTCGGCCACAGTGTTGCTAG
+ATGGTGGTGGTGGCATTGATGGAGAGTTCTTGTTTAGGGGCACGGTTGAC
+ATGGTTTCAGATGGATTGTTGGAGCGGGAACGTGATTGGCGGCTGAAATG
+GTATTACTAGGGTTTGATTCGGAAAATTTTCTTAGAAAAACAGTTTGGCG
+GGAAGTTTAAATTTTCTGATTAAAAATGTTGGCGTAAGTGGTGTCGAAGT
+GCCCCATTTTGGTTTGATCTACAAAAAATGCGGGAGTTGAGACAAAGACT
+TTTCAACTGATTTTGCAGGATTAAGCTGACGTCACATTTTCCTGGGGGAA
+AAATCCCCGCATTTTTTGTAGATCAAGCCGCAATGAGACAGCCTGACACC
+ACGTGTTGACGGGATATTTAAATTTTCTGAGAAAAACATTTTGGCGGGAA
+GTTCAAATTTTCTGAGAAAAACATTTTGGCGGGAAATTGAAATTTTCTGA
+CAAAAAAATTTTGGCGGGAAATTGAAATTTTCTGACAAAAAAATTTTGGC
+GGGAAATTGAAATTTTCTGACCAAAAAATTTTGGCGGGAATTCAAATTTT
+CTGGGAATTAACTTTGGGGAGAAGTTCAAATTTTCTGTAAAAATTTTGGC
+GGGAAATTGAAATTTTCTGACAAAAATATTTTGGCGGGAAAATCAAATTT
+TCTGAGAAAAAAAAATTTTGGCGGGAAATTGAAATTATCTGACAAAAATA
+TTTTGGCGGGAAAATCAAATTTTCTGAGAAAAAAAAATTTTGGCGGGAAA
+TTCAAATTTTTTTTTTTTGAAAAGAAAATTCTACGGACCGGAAACGGCCC
+AACTACGGCTCAAGAGCCGTCTCGGTCGGTAAATGTGTTTTTTGCTCTAA
+ATAATGCATTTAACGACGTAAAAATGCTTAAATTAGCCAACTGGTATCAT
+AGGTATTAAAAAAATTCGTTTTCTTAAAATCCATTTTTTCCTCTTAATGG
+CCATTTTTTTACATTCCCCGTAGTTTGCCCGTAATTGGTCCGTCCCGCTT
+TTCATATCCGTAGTTCACCCGTTAATGGTCCGTTCCCGGTCCAAGATCCG
+TAAACGGACCGTACCGGCTTTGCCTGTGGTCAGATATAACTAGTAAGTCA
+AGTGGTGTCAGGCTGCCCCATTATGGTTTGATCTACTAAAAATGCGGGAA
+TTTTTCCCCCAGAAAAACGTGACGTCAGCACACTCTTAACCATGCGATAC
+CAGTTGAAAAGTCTGCGTCTCTTCTCCCGCATTTCTCGGAGATCAAACCA
+AAATGAGGCACTTTGACACCACGTGGTAAGTTATAACAAACATAACAAGG
+TGTCGAAACTACTGTAATTATAGTCTTACTTCAATATACAACCTAATAAG
+AATCTCCACCACTTACCTCAAAAAGCTGAAAATATTCTTATTATGATGTT
+CTGGTGTGCTTCCACTTCCGGACCCCGATGATGCCCCATTCACATGATTG
+GAGTGCCATGATTGTGTCATTTCATTTGTTCCGTTTTTCGAGATCGGAGA
+TTTGGTGGAGCCTCCTGAAAAAACAGAAATAAATGTGGAATTATATGGGG
+GCTCATATGTTTTCGGAACTAACCTTTTTGGGAGAAGACTCTGGAGAGCA
+TTTTTGTGTAAACTGACTAACTTGTGCCACCCCCCGCACCCCATAGAATA
+AATTGGCTAAAATTTCGAAAAAAAAAACTCGCCACCGCCGTTATTCTTGT
+ATTTCTTCTCCTTATTCCGACTCCGACGCAAAGTGAAAATTGACGAGGAC
+GGCTGGAATAATGTTTTGTGTTTGTGTCTTGTGGAAGAGATGCAGAATCG
+CCGGAAGTTTAGAGGGGGTGGCGTGACTTACTGACCTTCCGGGTGCTCGG
+CGAGCCGTCCACGTCCTGAATTCGTTGCGGCGACATTGTGGTGATCTGGA
+ATATGTGGAGCGTAATCGAAATATTTAGGCTTAGGCTTAGGCTTAGACTT
+AGGCTTAGGCTTAGTCTTCGGCTTAGGCTTAGGCTTAGGCTTAGGCTTAG
+GCTTAGGCTTAGGTTTAGGCTTAGGCTTAGGCTTAGGCTTGGGACTGGGC
+TTAGGCTTGAGCTTTGGCCTAAGCTTAGGCTTAGGCTTACGCTCAGGCGT
+AGGATTAGGCTCTGGCTTTGGCTTTGGCTTAGGCTTAGACTTAGGCCTAG
+GTTCACGCTTAGGCCTAGGCTTACAAGAAATATCCTCATTTACCGACCGA
+CTGTGGCCTAGGATTTCAAAAAATGACCCTTTTTGAAAAATCGAAAAATC
+GAAATATCGACGAATTTTCGTTTTTGAGGCGTTTTTTTAATTTCAATTTT
+TATAATTTTTTTCGGTTTTTCGATTTTTCTTGAAAATACCAAACTCACCC
+TATGCAAGTTCTCCGACGACTTCGAACTCCTAACAGCGGTGAGCTGTGGA
+TGATGTATCATAGACAGTGAGCACGATGCTCTCATAGGCCTCTCGGCCTC
+CTCCAGCCCAAACCATACTCCAATATGCGAGGTTATTTTTCCCCACATTT
+GATTGAAAGATGGTATCTGCAAGTGAAATTTTTGGGTGGGGAAAAAGAAC
+GTGAACGAATAATTTGGAGCAGCGGGGGGGGGGGTGGAAAAATGAAGAGC
+TGCTCGGAGGAGGGAGCCGTACTACGAAATGAGAAGAGGAGAAGCCGGTG
+TGACGGCGGGGCGTTAATGGGTTACTAAAGCCTCCACATTCCCATTTTCA
+GCCGTTTCGAAACAAAGAAAATAGAAGAAAAAAAAGACAGATGAAAAATG
+ACTTGGGTGGGTTCGGTGAAAAACAGGAAGCAGGAAGAGTGAGGAAATTG
+GATGGTGGAAGAGTTTTGGCATTTCTAGGTTACCGGGAATCTTTAGAGAC
+ACCTGGGCTGTCCCATTACAGTTTGATCTACAAAAAATGCGGGAATTTTT
+CGCCCAAAAAATTTTCAACAAATTTAGATATTTTTTACATTTTTTCCCCA
+ATTTTTTCAGCCATATTTCAGCCATGACTGTCCTTTTTTTCGGGCAAAAA
+AAAATTTTCTCTGAAAATGTTCGAAACTACTAAATTATGCAAGAAGACAA
+TTTTTAAGGTTCGGAGATCAATTTTGAGTCCTCTAGCTTCAAAATTATCC
+ATTTTAGAAGAGTTTTAAAATTGTAATTTTTTACAAAAATTGCTCAATTT
+TGCCACTTTTTAATAGTTTTCTAAACCTAGATTTTCTGAATTCTGCATAT
+ATGAATTACCCGTTTTCAACAAATTTAGACAATTTTTTTCATTGTTTCCA
+AAATTTTTTTCAGCCATTTTTCAGCCATTACTGTCCTTTTTTTGGGCAAA
+AAAAATAATTTTTTGAAATTACATTACACACCTTCCATGTTTTCTTCGTA
+GATTTAAGGTCCATGTCCACTGCTTGGTGGAAGAGTTTTCCGAGTTTTTA
+GGTCACCGGAGAATTTGAGTTGGAAGAGTTTTCGCATTACTCCCCAACTG
+TGATAGAACTTCAAAAATGAATATGCAGGGACATCACTCAAATTTGACAT
+GTCAGTTTAAAGGAACACGCTGATTTTCCGAGTGGGTCTCGCCACGATCC
+AGGTGCTAAATTTTCACAGTTTTTAGTATGTACCTAGTGGCTTATTTCTA
+AACAACACGCGCATAACATCGGAGTGTCGTTGCATAGGCCACTCTAAAAC
+ATAAACAAATGTGTGAAGAAAAATTAAACACAACTAGCACGGATTTCTGA
+CGTCCCTCAGAAGTTGAAATGGAAGAGTTTTTGCCGAACTAGGCCAGGCC
+ATATTCGGGGTAGATTTACGGCGCGTCGCGGCTCGATTTTAGTTGTAAAA
+CTAAATGTATTTGTCCGTGTGGAGTACACGACTTTCCCAAGCGTTGTCCG
+GCAGGCGATTGTCAATGGAGCGCGAAAATTCAATGAGGAAGGCCAGAACC
+CCGTGGGATTTTGAAATTTTTTTCAGATATGACAAAAAATGACAATGCCA
+AATTTAAAATGCATTAATAGCGGACAGAGGAGAGAATAAGTAGGGAAAAA
+AGAAGAAAAAAAAAGACGGGCGGCGCTTCTCTCATAAAATAGTAATTGGT
+CATTCTAAGTGTGCCTATTGTTCCTTATTTTTCGCTTTTTCTTGGCTCAT
+TTTAGCTCAAAAACCAAATGTCGAAGAGTTTCTAGAGAACTAGGCCACGA
+GAGGGAAAAACTAGGTCACTGGAATTTCTACGCTAAAAATTTGGCCCAGC
+ATATTTACCTACGTGGCCGTAAAAGAGAAAGTTCGGCCACTAACTTTTTC
+GGGCTATCAAAAAAGGTTTACCAAAACTTTATAAAAAAGAAACCACTTGT
+GGAAAATGGCCGTGCATACTAAAGTTCGGCCACAAACTTTTTTAAAACTT
+TTTTGCTCAAATTGAAGTACAGGACCACTTCGATGGGCGGTTTTCACTAC
+TTGGCCGTGTAAGAGAAAATTCGGCCACCAACTTTTATTCAAGGCCACAC
+CTCCAAATCCTTCAAAGCTTCAAAAATTTTCTACGTGGCCGTGTACGAAA
+AAATTCGGCCATCATCTTTTTTTTGGGTCACGTCGCTAAATTCTTCAGAG
+CTTCAGAGATTTTCTACGTGGCCGCGGGAGAGAAAATTCGGCCACCAAAT
+TATTTTTTAAGGCCAAACCTCCAAATCCTTCAGAGCTCATATTTTCTACG
+TGGCCGTGTACGAGAAAACTCGGCCACCAAATTAATTTTGAAGGCCCCAC
+CTCCAATTTCTTCAGAGATCATATTTTCTACGTGGCGTGGCCGTGTACGA
+GAAAATTCGGCCACCAAATTCTTTTTTAAGGCCAAACCTCCAAATCCTTC
+AGAGCTCCTATTCCCTTCGTGGCCGTAGGAGAGAAAGTTCGGCCACCAAA
+TTAATTTTTTAAGGCCACGTCGCCAAATCCGTCATATTATGAGGAAAAAA
+GTAAAAAATAATACTAATAACAATTGAAGAAAAATTGAAAAATATAAAAA
+TATAAGAGACTAGTAAATGAAGAGGAATGAAGAGCGAATAGGAGGCCAGA
+GAGAGAGAGGGGAGGAAATTGTGCTGTTGAAGACCTTGAAGAGAGAGGCA
+CAGCAATAGATAAATTGAATTACAATGGGGTGAGGAGCCGGGTCTGTCCC
+CCCCCCCCCCCCCCCCCAAAAAGTGCGAACAAATGTGATGAAGCGCAGAG
+AAAATCGGGAGGGGGGGGGGGGGGGGGGGCTGTGCTCCAGGTTGATTGAG
+CCAAGTGTTTCGACTTTTTGCCGAACACGTTGAGCTCTCCGATGAGCCGG
+GCTCACCGGAGAGCCCATGGAGCCCCATGAAGCAGAGGGTCACAAGGTTT
+GAGACTTCCGGGAGATAGACTGCACAACGTACAAAGACTAAAACTTTTTT
+TTTTTGCAGGTGAGGCATGAAATTTAGAGCTTTTTTGCAACAAAATCCAA
+CATTTTTTTTGTAAAATAAGGTCAAATGACGAGTTTTTTCTATAATCTGG
+CCGAGAAAACCTGAAAATTGATCTACCTTGATAAACAGGGCGCGCGGGTG
+TAAAGCGGAGCGTCGTTGTGAAGCTGAAATATTGTTGAACGAATTCTGGA
+ATTCTGGCTTCCCTCATAAATTGAAATGGAAGAGTTTTTGCCAAACTAGG
+CCAGGCCATATCTGGGGTAGATTTACGGCGCGCTTTTTTTTGGGCATAAA
+ATTCCCGCATTTTTGTAGATCAAACCGTACAGCCTGACATCACGTGTTTT
+TGGCCCCGCTAAACAGGGCGCGGGTGTAAACATTCAAATATTATGTGAAA
+AAAACGCATGAATTTGAACAATTTTGCGTAGAATTTTTGAACAAAAAAAT
+ATATGAATAACTAATGCAAAACGAACAGAACTAAATTTTCTGAAATTGAA
+GAGAGGGGAAAAAAATTGGGAAATTTTGGACATTTTTCCCAACGACGCAT
+TGAGCCACCGGACCCAGATGAGCAAATAAACCGGGGGAGCAGGAGGAAAA
+TGGAAATGACAAAAAAGGCGGAGGAGGAGAAGCTCACGTATTTAGTATCC
+CATAGAAAGAGTCAATTTTCATAAACTGCGACAATTGACTACCAGGGAGC
+AGTTGCGCTCTACCGACAAAATCAAGCAAGGTCCACGTAGTGCCAGTCTG
+TCCCATTACGGTTTGGTCTACAAAAAAATGCGGGAAAATTTGGCTCAAAA
+AAATGTGACGTCAGCACACTCTTAACCATGCGAAATCAGTTCCCGCATTT
+TTTGTAGATCTACGTAGATCAAGCCGAAATGAGACACTGTGGCACCACGT
+AAAGGTCCTTCTTACAGAGTGCGCTAGAGCGCGATTGCCAGTTTTCTAAA
+AAAAAAATCTAACATGAAAAAATGTGCGTAAAAGCGGAGTTTCGTTGCGA
+TGTAAAATTTGGAGAAAAATTGAAAACTGAGGAGGAAGAAAAAGTTAAAT
+GCCTCTTCGCAAGACCGGGATTAAATAGTATTTTACTTCTTTTTTTTCCT
+TCAACTTTTTGAAATTTTTGGCGGAATGGGGAAAAGGAAAAAAAAACGAA
+ATCATCGATAAAAACAACACTAGGCCACCCAGAAGTAAACCTAGGCCACC
+TTATAGAAATTCTAGGCCACCCTGTAAGAATTTTAGGTCATCGCGTAGAA
+AAGCTAGGCCACCCTGTTGAACTGCTAGGCCACGCTGTTGTACACTTAGG
+CCACTCTGAAAAAAATCTAGACCTCCCTGTAAAAAATCTAGGCCACCTTG
+AAAGAATTTTAGGTCATCGTGTAGAAATTCTAGGCTACGTTTTCGAAATT
+CTAAACCACTCTGTAGAAAACTTGGGTCATCTACCGAAATTCTAGGCCAC
+CCTGCAGAAAACTTAGGCCATCTACCAAAATCCTAGGCCACCCTGTAGAA
+AACTTAGGTAATCTACCAAAATTCTATGCCACTCTGTAGAAAACTTAGGC
+TACCTCGTTAAAGTTCTAGGCCACCGTGTAGAAATCTTAGGCTACCTCGT
+TAAAATTCTAGGCCACCCTGTAGAAAAATTAGGTGATCTACCAAAATTCT
+ATGCCACCCAGAAGTAAACCTAGGCCACCTTGTATAAATTCTAGACCACC
+CTGTAGAAAACTTGGGCCATCTACCAAAACTCTAGGCCACCCTGTAGTAA
+ACTTAGGTCATCTACCAGAAAACCTAGGCTGTTCCGTTACGCCGCATGCT
+AAAAAATCCAGACCGCCCTGTAGAAAATCTAGGTCACTCCCTACAAAACC
+TAGGCCACCCTGTGAAAATTCTAGGCCACCTTGTGAAAATTCTAGGTCCT
+TCCCTAGAAAAACTAGGCCACCCTGTTAAACTCTTAGGCCACTCTCTAGA
+AAAACTAGACCACCCTGTAAAAAAACCTCGATGGCCTAGAAAAAAGCTTG
+GGAAATTTTGTGGAAAAAGTTAAAAAGGAAAATCTAGGCCACCCACAAAA
+AAGCTAGGCCACGTGGCAAGAAACTTCAAAAGTGACGAATGATGAGACGA
+GAGGCGTATGTTTGAGGTCAAAAAGGGTGAAAAAGAAGAAAAAAAGACGA
+GGCGGAATGTTTCTTTTTTCTTTTCAAACTGAGCATCTCCCCGTCTCTCG
+GCCACCAATACTACTACTACTACAACTATTCATGTTTTTAGAGAGCCCCC
+CCCCCCCCCCCCCCCGGCCACTTGTCAGCTTTTTTGACGGAAGATGCCAA
+CACACAATCGAAGGGGAAACCATAAAAACCCGCCAACGACACTCCGTTTT
+AAGGCCCGGATGCCCAGATGTATGAAAAAATGGAGAAACTGAAGGCTTCT
+CCCCTCCCCCCCCCCTCCCTTAAAAAATGATGAATTACTAATGGTGCCGC
+CCATGTTGTGTTTGTTGCTTTCCCCCCGTGCTCCATCATTGGGGGAACAT
+GACAGCCACCTTGAGTTACATGTATACAAAGTGACAGGAGGGAAAGATAG
+GGGTAAAAGTGCAAAAAGGGAGTCGCGGGTTCGAACCAGTGAGGGTTTGC
+AAAATTTGGGCTGTGCGCGGCGCCTTAGACTACTGCGCCACGCGTGCGAA
+CTGTAAATAGAACTGTCAGGCTAAATACGAACGTTCGGTTTTTAAACTCG
+ATTGGCAAAAATGAAATGAATGAATAGACAGGAATGACTCATATTTTTTG
+CATAAAGGGGCCTGGGTCTGGGAACTAGGAACTAAACTAAATGAAGGAAA
+ATTGAGGCATCTCCCGCCAATTGAGTAGAAAAGTGATGAGAGCGGCAAAA
+AGAGATAGGGGGGGGGGGGGGGACCCATTCATTTTACACTGGACACCACA
+CTCCCCACTCTCTCTTTGATGACGAAGGACATGAGTACGAACTCGCGAGC
+ACAGAAATACGACACGTTTTCTTCTCATTTTTTTTTTGCAAAAGGTGATG
+ATGATAATCGCTTCTAAACGAGGGGAAGTGTACTAAATAATAAAATTGCG
+AGTGGATATTGGATTTTTTCGTTATTTTCCGCTCTGAAAAACCTGAAAAT
+CAGTCGGAAATTCGAGTTTTGGCTAACTTTTTGTAAATTTTGTTTAAAAA
+ATCACTTTTCGCTGCGAAACCACCTGAAAGGATATAGTGGGCATGCGCCT
+TTGAGCGCTACAGTGGAGGGAATGCAGTATCTCTTGGAAGTCAGATTTGC
+CGATTGTTTTAACGCAAAACCTGAAGTATAGAAAAGAAAACATGAAAATT
+TATTGAAAATATAATAAATAAATTAAGCAAATTACATATCAACTGAGAAA
+ATCACCTGCTGGAGAGAAAAATTGAAAAAAAACCAGAAAATCGGCAGGAA
+AGCAATAATCGAGCAAGATCCTTGGAATTTTTAGGTGCAGATATCGGTTC
+AAAAGGAAAACACTATTTTAGCTTTTTTTTGTCTTAAGTTCAATGTTATA
+ACACAAGAAACGATATTTCTATGGCATAATTTTTGGGTCCTAGAAAGCAG
+ATTTTCACGTAGATTGGTCTGAAAATAATATTGGAGTAATTTTTATTATT
+TTTCCTTGCATTATAAAATTATTTCTCTTTTATTTCTCAATTCTAAAACT
+ATTTTCCCGTTCTTTTTCCCTATATCTCGCGCTTCTCCGGGATGTTGCAT
+CCCATTCGACGTGAGGAGTCTCGGAGTCTCTCCGCTGCAAACGCGCTCCA
+CTGGACACAGAAAATAAAAAAAATAAATTGTTCGAATTCATGCAATTTTC
+TTCTAATTTTCTCCGTTTTTCGTCAATTTTTCTGCAAAAAAGACAAAATT
+TACAGGTAGCAATGTATGGGGGATATCAAGGAGCATATGGGTAAGGCTAA
+AAACTAGGAAAAACTAGGAAAAACCCATGGAAAACTAAAAAACTCTGAAA
+TTTCAAATTTCAGAGCCTACGGGAACCAGCAGGCGGCTTCACAACCATAT
+CAACAGCAAGGACAACAGAATTATTACCCGTAACTCGAAAAAAATTCAAA
+AAATTCGAAAAAAATCAATTAAAAAGATCAAAATTTTCAATTTTTTCAGC
+GGAGTGAACCCGTACGCGGCGAATTATGGGTACGCGGCAGCACAGCTTCC
+ACCACCACCTCCACCACCGCCAGTATGCCTTAAAATTGAAGAAAATTTGA
+TTAAAAAATTGAAAAAATGCAAATTTTCAGGTAGCCGATCCATACGCCGG
+CCAATTTCAGACATTTCCCTCTCAAGCCACCAAAATAGCGCCGAATCCCT
+ACTTTAAAAAGCCACAAAATCAGCAGCAACAGGGTATTTTCGCCGTGTTT
+TCTGGCTGCAAAAAAATTAAATTATCGATTTTTTTAAGGCTACGACGCGG
+CGGTCTACAATTACGCTCAGCAGAATACTCCGAAAAATTGGAAACACGGC
+GGCGGCGGCCGGCAGGGGAGACAGGGATCTGGCGATAATAAACAGTACTA
+TTGTGAGGTAAAAAACGTGGAAAAAATCGAGTAAAACACAGTTTTTTATT
+CAAAAATCTGAGAATTTCCGTAAAAAATCCTGTTTTTTGACGTTTTTAAG
+CAAAAAAATCGGGTTTACAGCACTTTTAGAGATAAAAAAGTGGAAAAAAT
+CGAATTTTGGACCTGATTTTGGGCTTGAAAGCATGATTTTTATCAGAAAA
+CACAGTTTTTTTTGTCAAAAATCTGAGAATTTCTATGAAAAGTCTTGTTT
+TTGGATGTTTTTAAGCAAAAAAATCGGGTTTACTTCATTTTTAAGGGTAC
+AAAAGTGGCGAAAAGTTAATTTCTTGTAAATTTTCACATGCAAAATATTG
+AATTTATTAGGTTTTTTCCAGAAAAAGTAGTTTTTTTGCTACATTTACAG
+GCTTTTAAAACTGAAAACATGTTAAATTTCGAGGAAAATCGACAAAAAAA
+CCCATCTTTTGGCCAAATTTAAATTTTTGAGCAAAAAAATCGGGTTTGCA
+GCACTTTTAAAGATAAAGAACTGAAAAAATTCAATTTCTTGGAGAAAAAA
+GCAATTTCAACACCAAAAATAGCAAAAAATTCGGGAAAATTGTCAATTTT
+TTTGAAAAAAAACTTGAAAAACCGGATTTCCAGTTGTTTTTTCATGATTT
+TTTCTCAAAAATCTCATAAAAATTGGAAAAAATTCCGAATTTTTTACTGA
+AAATTCGAGAAAAATTGAAATTTTTTCAATTCCGATTTAAAAAACATTTT
+TCGCTAAAAAATTGAATATTTTTAGGCTTTAAAGTTCGGAAAAGATGCTG
+AAAATTCGGAATTTTCTGTTTAAAGAAATTTTTTTTGTGCTGAAAAATTG
+ATTATTTTTATGCTCCAAAAACTGGAATTTTTGAAAAATTCGGACAAAAA
+AATTTTTTTATTAGTTTTTAAATTTTTTTAATTTTTCAACCCGCTTTTTG
+CCCAAATTTAGATTTTTTATTTAAAAAATCGGGTTTACAGAACTTTTAAA
+GGTAGAAAAACTGCAAAAAGTTAATTTCTTGGATATTTTCAGGCTTTAAA
+GTCCAAATAAACATGTTGAAAATTGAAATGTCTTCAATTTCGATTAAAAA
+CATTTTTTTCGCTAAAAAATTGAATATTTTTAGGCTTTAAAGTCCAAAAA
+ACAAGCTGAAACTTGAATTTTTTTCATTTTCAATTTAAAAAAATTTTGCT
+CAATAGATTTTCAGGCTCCAAAACACTGGAATTTTGGACTTAATCGAAAA
+TTCGGACAAAAAAATATTTTTATTAGTTTTTAATTTTTTTAATTAAAAAA
+AATCCCAATTTCCAGGTGTGCAAAATCTCATGCATTTTTAGGGTTAAAAT
+TGGAAAAAATTATCAAAAATTTTCGAATAAAAATGGAATAAATCTGATTT
+TTATAAATTTTTCGAAAAAAAAATGATTTGTTGGCAAAAATTAAATATTT
+CAGGCTTTGGAAGTCCAAAAACCATGTAGAAAATTCGGAAAAAATCGAAA
+AATTGGAAGAAAAAAATTTTTAATTTCAAAAAATTTCAAAAAAATATTTA
+AAGCTGGTGTAGTCGACTTTATTTATTGCTTAAGTAGACTCTAAATTGCC
+TGGAAACACCGAATTTCATAATGAAACTTCTTGAAAACTTCTCAAAAAAA
+AAAGTTATGACGGCTCAAAAAATGGACTAAAATTAGTTAAAATTTGAAAT
+TTGACCGACTTTTCAAGCGGCTGGAAACATTTTTTCTTTGAAATCACCGT
+CAAATTTTGAGTATACTGTGCAATTATGTTGCGTTTTCAACTTCATTTAG
+GTATTTTAAAGTCAAAGGGCGGCGAGATTTTTAATTTTTTGAACCAAATC
+TCGCCGACCATCGACTTTAAAATATCTAAATCGAGTTCAAAACTCAAGAT
+AATTACATTATATAATCAAAATTTGACGGTGATTTCAAAAAAAAGGTAGT
+TTCTAGCCGCTTGAAAAGTCGGTCAAATTTCAAATTTTAACCAATTTCAG
+GCCATTTTTTTAGTCGTCATAACTTTTTTTCGAGAAGTTTTCAAGAAGTT
+TCATTATGAAATTCGTTGTTTTCAGACAATTTTGAGTCTGATAAAGCAAT
+AAATAAATTCGACTACACCGCCTTTAAATATTTTTTTGAATTTTTTTAAA
+ATTAAAATTTTTTTTTCCAATTTTTCGATTTTTTCCGAATTCTCCACGTG
+GTTTTTGAACTTCCAAAGCCTGAAATATTCAATTTTTGCCAACAAACTAT
+TTTTTTTTCGAAAAATTTATAAAAATCAGATTTATTCCATTTTTATTCGA
+AAATTTTTGATAATTTTTTCCAATTTTAACCCTAAAAATGCATGAGATTT
+TACACACCTGGAAATTTGGAATTTATTTGTAGAATTTTTGGATTTTTTAA
+TTAAAAAAAAGTTTTTTCCGATTTTTTTTCCGAATTTTCAACATGGTTTT
+TGAACTTCCAAAGCCTGAAAATGATTTTTTGAATAACTTTTTGATTTTTT
+CGGTTATTTTTGGTTTTTTTTTTTAATTTAAAAAAATTAAAAAATTAATA
+AAAATATTTTTTGTCTGATTTTTCGATTAAAGTCCTGAAAAAAAAATCTA
+TTTTATAGCAAAAAATCCTAATTTTCAGCCTGTTTTTTTGCCTTGATATT
+CAATTTTTACAAAAAAATTTTTTTTGGAGTTTTTTGCCTAAAAAATCGAA
+AAAAAAAATCATCTTTTCTCGAATTTTTGGAAGAAAAATTAAAAATTTCA
+AAAATAATTCAATTTTTTGGTGTTTTTCGGGTTTTTTACATAATTATTTT
+TTAATTTAAAAAGTTTGTAAATAACCATAAAAATTTATAATTTTTTAAAT
+TAAAAAATAATTATTAAAAAAAACTCGAAAAACACCAAAAAATTGAATTA
+TTTTTGAAATTTTTAATTTTTCTTCCGAAAATTCGAGAAAAGATGATTTT
+TTTTCGATTTTTTAGGCAAAAAACTCCAAAAAAAAATTGTTTTGTAAAAA
+TTTAATATCAAGGCAAAAAACAGGCTGAAAATTCGGATTTAAAAAAATAA
+TTTCTTGCTATAAAATAGATTTTTTTCAGGACTTTAATCGAAAAATCAGA
+CAAAAAATATTTTTATTAGTTTTTTAATTTTTTTAAATTAAAAAAAAAAT
+CAAAAATATCCGAAAAAATCGAAAAATTATTCAAAAAATCATTTTCAGGC
+TTTGGAAGTTCAAAAACCATGTTGAAAATTCGGATAAATAAAAATATTTT
+TTTGTCCGAATTTTCGATCAAAGTCCAAAAACTTCCAGTTTTTGGAGCCT
+AAAAATAATCAACTATTGAGCAAAATTTTTTTAAATTGAAAATGAAAAAA
+ATTCAAGTTTCAGCTTGTTTTTTGGACTTTAAAGCCTAAAAATATTCAAT
+TTTTTAGCGAAAAAAATGTTTTTAATCGAAATTGAAGACATTTCAATTTT
+CAACATGTTTATTTGGACTTTAAAGCCTGAAAATATCCAAGAAATTAACT
+TTTTGCAGTTTTTCTACCTTTAAAAGTTCTGTAAACCCGATTTTTTAAAT
+AAAAAATCTAAATTTGGGCAAAAAGCGGGTTGAAAAATTAAAAAAATTTA
+AAAACTAATAAAAAAATTTTTTTGTCCGAATTTTTCAAAAATTCCAGTTT
+TTGGAGCATAAAAATAATCAATTTTTCAGCACAAAAAAAAAATTTTTAAA
+CAGAAAATTCCGAATTTTCAGCATCTTTTCCGAACTTTAAAGCCTAAAAA
+TATTCAATTTTTTAGCGAAAAATGTTTTTTAAATCGGAATTGAAAAAATT
+TCAATTTTTCTCGAATTTTCAGTAAAAAATTCGGAATTTTTTTCCAATTT
+TTATGAGATTTTTGAGAAAAAATCATGAAAAACCAACTGGAAATCCGGTT
+TTTCGAGTTTTTTTTCAAAAAAATTGACAATTTTCCCGAATTTTTCGCTA
+TTTTTGGTGTTGAAATTGCTTTTTTCTCCAAGAAATTGAATTTTTTCAGT
+TCTTTATCTTTAAAAGTGCTGCAAAAAACTACTTTTTCTGGAAAAAACCT
+AATAAATTCAATATTTTGCTTTTTTTTTTCCTTTTTTTGTGAAAATTTAC
+AAGAAATTAACTTTTCGCCACTTTTGTACCCTTAAAAGTGCAGTAAACCC
+GATTTTTTTGCTTAAAAACTTCCAAAAACAGGAATTTTCGGGTTGAAAAA
+TTAAAAAATTTTAAAAACTAATAAAAATATTTTTTTGTCCGAATTTTTCC
+AAAATTTCAGTTTTTGGAGCCTAAAAATATTCAATTCTTTAGCGAAAATT
+GTTTTTTTTTCAAAAACTTCCTACGACTACACCACCTTTAAAAAACCAAA
+TTAAATTAGAGAAATTCTTCAAAAAATCCCCAAATTTCCAGGTTTGCAAA
+ATCTCGTGCGCCGGCGGAATCACATACAAAGAGCATCTGGAAGGTCAACG
+GCACAAGAAAAAAGAAGCTATGGCAAAACAGGGCATACCGAGCACTTCCC
+TCGCTAAAAATAAGCTTTCCTATCGTTGTGACCTATGTGACGTCACTTGC
+ACCGGTCAGGACACGTATTCGGCTCACGTTCGTGGCGGAAAACACTTGAA
+AACTGCACAATTGCACAAAAAATTGGGAAAACCGGTGCCTGAAGACGTTC
+CGACGATTATTGCTCCGGGAGCCGATGGGCCGACGGAGACGAAAGCCAAA
+CCGAAATGGCATCAACAAGCTCTGCCTGGCGGGAAAATGTGCGGAATTTG
+AAAAAAAAATTTTGGAAAAAAACGAGAAATTGCACATTTTTAGGCTCAAA
+AATCTGAAAATTTAGCAAAAAAATTTAGAAAAATTTGGATTTTTAGAAAA
+AAATTAGCGTTTTCTCGCCAAAAATGCTCAATTTTCGATAAAAATGTACA
+TTTTTTTTTTTGGATTTTTAAAAAAATATTTTAGGGCTCAAAAATCTGTA
+AATTCTGCAAAAAAAATTCTAAAAAATTTTGAAATTTTGAGATTAAATCT
+TTCGCCAAAAAAACGAAAAATTTGAATTTTACAACTTAAAATGCTCAATT
+TTCGAGGAAAATGTAAAATTTTTTTTCAATCTGAAATCTGTAATTTCTTT
+TAAAAAATCGATTTTTTAAAAAATTTCTACTGTAAAATTTTGAAAAAGTT
+GAACGACGTCAAAAAGAAGGTAAAAATCCGAAAAAAAGCAACAAAGAACT
+AGGAATTTTAAAATTTCCAAAAATGGTCTGAAATTTTGAGAAATCAAAAA
+AAACAAGTTTCTTTCAGTTTTTTTTAGAAAAAAAAATCGTATTTCAGAAT
+TTAAATTTAAAGCATATTTTAAACTTTTAAACGCAAAAACATTATATTTT
+TCTTTAAAAAAAAAACAATTTAAACGCATTTATTGCTTTATTAGACTCAA
+AATTGTCTGAAAACACCGAATTTCATAATGAAACTTCTTGAAAAAAAAAA
+GTTCTCAAAAAAACAAGTTATGATTGCTCAAAAAATGGCCTCAAATTAGC
+GGAAATTTGAAATTTGACCGACTTGTCAAGCGGCTGGAAACTAGCTTTCT
+TTTTTGAAATCACCGTCAAATTTTGAGTATAAAATGTAATTATCTTGCGT
+TATCAACTTGATTTAGGTATTTTAAAGTCGATGGACGGCGAGACTTTTAA
+AGGTGGAATACCGAAATTTAAGACTTTGCTTTTTTAGACCGAAATTTTGG
+CAACTTATCGGTGCGACACTGCAAAATTGCCAAAGTTTGAGATTTTAGCT
+AAAAATAGGCCGTTTTTTCCAAAAACTTTGATCGGCCATAACTTTTTTTT
+GGAAAATTTTCAGAACGTCTCATTACGAAATTCGGCAGTTTTGGGCCATT
+TTGGGTCTAAAAAAGCAAAGTCTTAAATTTCGGTACTCCACCTTTAAAAA
+TCTCTCCGTCCATCGACTTTAAAATACCTAAATCAAGTTGATAACGCAAG
+ATAATTACATTTTATACTCAAAATTTGACGGTGATTTCAAAAAAAAAAAG
+TTTCCAGCCGCTTGGCAAGTCGTTGAAATTTCAAATTTCCGCTAATTTGA
+GGCCATTTTTTGAGCAATCATAACTTGTTTTTTTGAGAACTTTTTTTTTC
+AAGAAGTTTCATTATGAAATTCGGTGTTTTCAGACAATTTTAAGCCTAAT
+AAAGCAATAAAAAATTAGAATATACCACTTGAGAAAAATTAAAGATTTTT
+TTAAGTTTAAAATAAAAAAATATGTTTCTTTCCGATTTTTTGATAGTGAG
+ATAAAAGTTTTGGCGGGAAATTCAAATTTTCTAGAAAAAAAATTGAAAAA
+ACTCATAGTGTATAACTGCACAGAACGGCTGGTTATGAGTATAGGTGTCA
+AAGTGTCTCATTTCGGTTTGATCTACAAAAAAAGCGGGAATTTTTCCCAA
+AAAAAGTTACGTCAAGATGCTCTTTTTTATTAAATTTAATTAAAAAAGAG
+AGCATGCTGACGTAACTTTTGAGGAAAAATTCCCGCTTTTTTTTGTAGAT
+CAAGCCGAAATGAGACACTTTGACACCACCACGTTCAGACAAAATCCCCC
+ACTAAATATTTGGTAAAACTAGTTCAAAACCCGACTGTAGTACATTTTTG
+GCAGAAATTTGAAAATTTCAACTTAAAACCGCTCAATTTTTCCAAAATTT
+CACAGTATGCATTTCAAAAATTATGGTTTTGTTTTTTTTTAATCGAAAAA
+TATATTTTTAACAAAAATGGACCATTTTTAGTTGTAAAATTCAATTTTTT
+GGCGCTTTCAAATTTTTAGGCAAAAAATGTGCAATTTTCTCCAAAAATTT
+TCAGATTTTTTAACCCTAAAATTAAAAAAAAATCTAAAATATTAGAATTT
+CCCGCTTTTTTTTTCAAATATTTCAATTTTTCCAATTAAAACACAAAAAT
+TGAGCATTTCTAGTTGGCACATTCAAATTTTTAGGCGAAAAATTTGATTT
+CAAAATTTCAAAATTTTTCAGAATTTTTTTTTGCTAAATGTTCAGATTTT
+TGTGCGCAAAAATATTTGAAAAATCCAAAAAAAAAACTCGAAAATTGAGC
+ATTTTCAGTTGTAAAATTCAACTTTTTAGGCGGAAAAATGTGCAATTTTT
+CCCCAAAAAATTCAAATTTTCCAACTTTTCTCTCAAATAGCACAGAAACA
+GAAAATTTGTTATACCTAATGTGGAAAAACTGAATTAAAACAGATTTTTT
+GAAAAAATGCACTTTTTTTTTTGCCAAAAAATAGTTCAAACCCCGACTTT
+TTGTTCCAGAGTTTCCAGGTCATCGGTATCATCGCATAAATAAATTTTGC
+GGGAAAAATTCCCGCTTTTTTTGTAGATCAAACCGAAATGAGACACTTTG
+ACACCCCACGTTCAGACAAAACCCCGACTTTTTTCCAGAGTCATCGGCAT
+CAACACGGTAAACTTCGTCGGCGGTACGAAGCTCAACTCCACCGGACAAC
+TCGAGGAGAAGAAGCGCGAAGTTGCTGCCGCCGTGAGCTCAGTCGGCCGG
+AAAACCGGTGGTGCTGCTGCAACGACGACGATTGAGGTGGAAGACGAGAA
+GCTCCGAGCAATGATCGCCGCCGAGGAGGTACAACCTGTCGGCGAGGAAC
+ATGTCACTGAAGAACGTGATGCTACCGGAAAACTGGTGCAATTCCATTGT
+AAACTGTGCGATTGCAAGTTCTCCGATCCGAATGCCAAGGAGATTCATAT
+CAAAGGTCGTCGACATCGTGTCAGCTATCGGCAGAAGATTGATCCGACGT
+TGGTGGTGGATGTGAAGCCATCGAACAAAAGATCACAGGAGAAGCGGAAG
+AATCAGCTTCCAGCAGTTCATGGTGTGTGGATTTTTTAACAAAAAATCAA
+CAACAACACAAAAAACATGTTCCAATAAAATTGGAAAAAAAAATTTAAAA
+AATCCCAAATTTCCAGGTGTCTAAAAATCTCATGCATTTTTAGGGTTAAA
+ATTGGAAAAAATTATCAATTTTTCGAATAAAAATGGAACAAATCTGATTT
+TTATAGAAAAAATAATAATTTGTTGGCAAAAATTGAATATTTCAGGCTTT
+GGAAGTTCAAAAACTATGTAGAAAATTCAGAAAAAATCGAAAAATTGGAA
+GAAAAAAATTTTTAATTTGAAAAAATTCAAAAAAATTTAAATTTTTTTAA
+AAATTGAATTTTTGAGTAAATAATTTTTTGCTATAAAATTCAATATTTTC
+AGGCTTTCAAGTCCAAAAACCGTGTTGAAAATTCCGAAAAAATCGAAAAA
+TTGGAAAAAAAATTTTAATTTAAAGGTGGACTACGCTCAGTGGGGGGAAA
+TTGCTTTAAAACATGCCTATGGTACCACAATGCCCGAATAGCATAATAAA
+AAAATTTTAAAAAATATTCTAGATTTTATATGATTTTTTGAAAATTGGAA
+AAATCACAGTTTTTGCCTAATTCCTATTTGAATTACCGCCAATTGGATTT
+GTTCGGTGGAGCGCGCTTGCATGTTTTTAAATTTATTTATTTTATTTATT
+GTTATTTTCCACCGATTTTTAATGTTTTCGATGTATTTTTGTTTGAATTT
+TAGAGAAAAAGTCAAAATAAATACTAATTATCGATTAAAAAGCACGCTTA
+CAGGCGTAAATCAGTGAAATTAATTAACTCAGGTTCGAAATCGTTTAAAA
+TCGTTACTTTTTCATTTTTACGCCTGTAAGCGTGCTTTTTAGTCGAAAAT
+TTGCATTTATTTTCACTTTTTCTTTAAAATTCAAGCAAAAATACACCGAA
+AACATGAAAAATCGGTGGAAAATAACAAAAAATAAAATAAATAAATTTAA
+AAACGTGCAAGCGCGCTCCATCGAACAAATCCAATTGGCGGAAATTTAAA
+TGGGAATTAGGCAAAAACTGAGATTTTTCCAATTTTCAAAAAATCATATA
+AAATCAGAAAAATTTTTGTTTTTTTTTTAATTTTTTTAAACATGACATTC
+GGTCATTGTGACCCCATAGGCATGTTTTAAAGGTGGTGTAGTCGAATTTT
+TTTTATTTCTTTATTAGACTCAAAATTGTCTGAAACCCCGAATTTCATAA
+TGAAACTTCTTGAAAAATTTTCAAAAAAAAGTTATGGCGGCTCGAAAAAT
+GGCCTAAAATTAGTGAAAATTTGAAATTTGACCAACTTATCATTGTCGCA
+TCGGCTGGAAACAATTTTTTTTTTGAAATTGTCGTTCAATTTTGGGTGTA
+CAGGTCGATTATCTTGCGTTTTCAGCTTTATTAAGGTATTTAAAAGTCGA
+TGGACAAATGGATCTGTCAAATTTTTTACCAAATCTTTTCGTCCATCGAC
+TTTTAAATACCTAAATAAAGCTGAAAACGCAAGATAATCGACCTGTATAC
+CCAAAATTGAACGACAATTTCAAAAAAAAATTGTTTCCAGCCGCCGCAAC
+AATGATAAGTTGGTCAAATTTCAAATTTTCACTAATTTTAGGCCATTTTT
+CGAGCCGCCATAACTTTTTTTTTTGGAAAAGTTTTCAAGAAGTTTCATTA
+TGAAATTCGGTGTTTTCAGACAATTTTGAGTCTAATTAAGCAATAAAAAA
+AATTCGACTACACCACCTTTAAAGCAATTTCCCCACTGGGCGCTACTCGA
+CCTTTAAAGGGGGAGTAGAGTTTGTGGGTATTTTGCTTAAATAGACTAAA
+ATTGGTCCAAAACCACCGAATTTCATAATGAGACTTCACAAAAAATCTCC
+AAAAATTTTTTATGGCCGGTCAAAATTTCGAAAAAAAAAGATGCAACTTT
+TGCTAAAATCTGAAATTTCGCACACTTTTCTTTGTCTAGCAGCCGCTGGA
+TTTTAGTTTTTCTAAAATTATCACCCTCTAATCCTTCTTTTTGGTAATTT
+ATCTCGCGAAAATCCGTTGATTGAGACAACTTTTAGGCCGATAGGCATCC
+AAAAATGATCAATCTAGGGATGCCTATCGGCCTAAAAGTTGTCTCAATCA
+ACGAATTTTCGCGAGATAAATTATTAAAATAAGGATTAAAGGGTGATAAT
+TTCAGAAAAACTAAAATCCAGCTGCTGTGACAAAGAAAACTGTGCGAAAT
+TTCAGATTTTAGCAAAAGTTGCATCTTTTTTTTCGAAATTTTTTATTTTG
+ACCGGCCATAAAAAATTTTTGGAGATTTTTTGTGAAGTCTCATTATCAAA
+AATTCGGTGGTTTTGAACCAGTTTTAGTCTATTTAAGCAAAATACCCACA
+AACTCTACTCCCCCTTTAAAGGAATGAAAATAATTATTGGAACGTTTGTT
+TTTTAAAATGATTTTTTGTTAAAAAATCCACACCGACGAAAAATCCACAG
+TTTCAGAGCCTCCGAGCTTCATGAAAACGCCGTGGTTCGCCCCACCGGCT
+CCAGAAGGCCGGGAATTCAATATAGTAGATGATAGAACTATTAACGAAAA
+GTACGCCGGGCTTAATCCGGGCGTCGAGTTCATTTCCAATGTGGATCGCC
+TTATTTCGGATATCAATGAATCGCTGAAGTATGTGTCGGATAAGATCGAG
+CGAGACGTTCGGAAGATCCCTGAAGACGTGGTGGAGCTTCCCACCACCAC
+CACCACAACGGAGCAGCCGCCGCGGACAGTGTTGGGATGCTCGAGAGTTG
+GAATTATTGCGAAGGGAACGTTCATCAAAGGGGATCGGTGTGCGGAGGTG
+GTTCTGACGTGTACGCCGGTGCCGACTTCGGGGCTTGTTGAGCAGATTAG
+GCGGTTGTTTGGAGAGTCGACGGTACGGGCCGGCCTTTTTTTTTTGCCGG
+AAATTTGGGGATTTACCGGTTTGCCGGAATGTTTTTTTTTCCGGCAAATT
+GCCGGTTTTCGCCGGAAATTTGAAAAACGGCAAACTGGCAATTTGCCGGA
+AATTTTCAGTTTCGGCAAACTGCCGCGATTTGCCGGATAACAATCGTTTA
+TTCCGGCAAATTCGGTAAGTTGCCGGTTTGCCGATTTGCCGGTTTGTTGA
+ATTTAGCGGAAATACGGCAAACGGCAAGTTGCCGGTTTCCCGACTTACCG
+GAAATTTGAAAAACGGCAATTCGCCGGTTTGCCGGAAATGTGAAAAACGG
+CAAATTTCAGAATTCGGCAAGTTGCCGGTTTTTGCCGGAAATTTTCATCT
+TAGGAAAATTGCCGGTTTTTGCCTGAAATTTTCATTTCAGGAAAATTGCC
+GGTTTGCCGGTTTGTCGAATTTTCCGGAAATGTGGAAAACGGCAAGTTGC
+CGGTTTGCTGATTTGCCGGAATTTTTAATTTTCGGCAATTTACCGATTAG
+CCGGAAATTTTTTAACGGGATTTTTGATAAGACGGATTTTTTTCCGGCAA
+ATTCGGCAAGTTGCCGGTTTGCCGGAATTTTTCATTTTTGACAAATTGCC
+GATTCGCCGAATAATAATTATGCCAGAAATTTGAAAAACGACAAGTCGCC
+GGTTTGCCGATTTGCCGGAAATTTCAAAAAACCGGCAATTTGCAGAATTT
+TGCCGGAAATTTTCATATTCGGCAAAGCTACCGATTTGTCGGATTTTTTA
+AACCGGTTTTTTCATAAGATAGATTTTTTTTCCGGCAAATTTCCGGCAAG
+TTTCCGGTTTGCCGGAAATTTCAAAACCGGCAATTTTCCGAATTCTGCCG
+ATTTCTTGTTTGACAATCTCAATAATTACACAGACATCTCTAACAATTGA
+GCCGGATCCCGAGTCCCCATCAAGCCTTATCGTCACAGCTAACTACTTTC
+CCAATATGAAATGTCGTATTCTAATCACTTCAGCTGTAGTTAGAAAAGAC
+GATGATAGTATTGTAACTGGATGTGCTGCTGATAAGGATTTGTGCATTTA
+TGCGCTCGCTTCTATTCGGAATACAAAGTGGTATGATGTGAGTTTTTTTT
+AAATTTTACACATATTTTAAATTACTTTATCATTGGAAAATCTAATAAAT
+TAGAGCCCAGTTTACAAAAAAATCTATATTTTTCCAAAAAAAAAATTGAA
+AAAAATCGATAATTTCTCAAAAAATGTTTACAAAATCGAACTTTTTCCAA
+AAAACTTTGAAAAAATCGATAATTTTAAATAACTGCTGACAATTAAAAAA
+AATCGAAAATTTCTCAAAAATTGAAAAAATTAATATTTTTCCAGAAAAAA
+TTGAAAAAAATCGATAATTTCAAATAATAGCTGAAGATTTTTTAAAAAAA
+TCGAAAATTCGAACCTTTCTCAAAAAATTTGAAAAAAATCGATTTTTTTT
+CCAAACTTTTTTTCATCAAAAATTTCTCAAAAATTTGGAAAAAATTAGAA
+AAAATCAATATTTTTCCGAAAAAATTTGAAAAAAAAATCGATAATTTCAA
+ATAATAGTTGCAATTTTTAATTTAAAAGCGAATTTTTCAAAGATTTTTCA
+AATTTTTCACGTTTTTTTCTCTGGTTTTTTTAAATTAAAAAGCGTAATTT
+TTACCGAATTTATCATTAAATTACATGAATTTTTCTGAAAGAGCGAGAAA
+ATTAAAATAATTCGGAAAAAAAACAATTTTTTTCCAAATTTTCCAAAAAA
+TCCCACAGAAACCACCAAACTTTACTTTTTTTTTTTAACAAAAAAAAGTT
+TTAAAAAATATCAATTTCCGGCTTTTTTTCTGCCAAAAACTTTGGAAAAT
+GTGGGTAATTTTGGCTTTAAAAGTTTAAAAATTGAAAAAATCAGGAAAAC
+TTTTTGAATTTTCAGAGTCACTGCCAATACTTGAACTCGTGCCAATCAGT
+TATTCGACTGCTCCGAGATTTGCGAAATAAATATCCTGAAGTTGCGTGTC
+TTGATGATTATGTAAGTTTGAGAGTTTGGAAAAATATTCGAAATTTTTTG
+TGAAAAATTTGGTAAAAGTTCAAAATAATGTATAATTCTTTAATTTTTTT
+GCGAAAAAATTAATTTTTTGAAAAAAATTCTCTATATTTTTTGCTAAAAA
+GTTTAAAAATCTAAATAGTATGAAAAAATATTTTAGCAGAATCAACAAAA
+ATTGTATAAATTCATAATTTTTTGAAAAAAATGAAATAAATTTTTTTTTG
+CGAAAAAAATATGCGAAATAGGTTTTTTTAATGCAGGAAATAGTTTTATA
+GCTGAAAAAATGAGAAAAAACGGAGAAAATTGAAAAATTACGTACATTTT
+GCAGATTTTTTGCTCACAATTTTGTAAAAATTTCGGCAAAAATATCACCT
+TATTCAAAAAAAAATTGCTAAAAAAAATTTTTATAATACAAAAAAAATAT
+GAAATCTATCTATTTTTTTCAAAAAATCTACCTAAAAATCTATTAATAAT
+TTTCAATTTTTTTGTGAAAAATTTTGAAAAAATTCAAAATAATGTATAAT
+TCTATAATATTTGGCGAAAAAAATTAATTTTTGAACTATAATTTTTTTTT
+TGAAAACTAGTTTCAAAAATCGATATTTCACCTAAAAAAAACCCTAAAAA
+TAGGCGGCAAACTATTTTTCCGGCAAATCGGTGGTAATTGCCGAAATTTT
+TGGCAAATTGTGGCTTTGCAATTTTTTTTTTGTTGGAAATTTCAGATTTT
+CAAATTTAATCGGCAAGAAAACTGAAAAATCCCGTTTAAAAAATTCCGGC
+AAATCGGCAAACCGGCAAATTGCCGAATATAATATTAGGTCTCCTAATAA
+GTTCCGGGTCAAAAATCATAACCTTGTTCGCTGTGTATCGATTTTTATGA
+AACTTTGGGAGTTTATGTTATCAACCATGATCTTTCAATTGACAATAGTC
+ACAAAATTTTTTGACCACCCCAAGTGCCCGTACTCGGAGCCAATTTTTTC
+AGGCATTTTTCTGATCTCGCTTCTTTTTATCTTTGAATTGAGGTTTGTGT
+GCGGATTTTGCTTTGTTTAGAATACATCATTAGAAAACGAGAAAAGTTTG
+GAAAAAAATCTGTCCAAAAAATTTTTTTTGGTTGATCGTCAAAAAAGCTT
+CAAAAAGATTTTTGTCGAAAATTCTAGATTTTTCATACAAAAATGATGTA
+ACCAAGTGTAAATTATTTTTATACATACAAAACATATCAATTTAGTTCGA
+TACACTAAAATGATAATAAAAAATATAATTTTTTCGGATAATTTTTGAGT
+TTTTTGAATATTTCTTAAGTTTCAAATTTCAAACTAAAAGGATTTGTGTG
+TGTAAAAATAATTTACACTTGGTTACATCATTTTTGTATCAAAAATCTAG
+AATTTTCGACAAAAATCTTTTTGAAGCTTTTTTGACGATCAACCAAAAAA
+AATTTTTTGGACGGATTTTTTTCCAAACTTTTCTCGTTTTCTAATGATGT
+ATTCTAAACAAAGCAAAATCCGCACACAAACCTCAATTCAAAGATAAAAA
+GAAGCGAGATCAGAAAAATGCCTGAAAAAATTGGCTCCGAGTACGGGCAC
+TTGGGGTGGTCAAAACATTTTGTGACTATTGTCAAATGAAAGATCATGGT
+TGATAACATAGATTCCCAAAGTTTCATAAAAATCGATTTGCAGCGAACAA
+AGTTATGATTTTTGACCCGGAACTTATTTGGAGACCTTATACAATTTTTC
+AACATTTTCCAGAAAATGGAGCTAATCGTCTCGAACATTATCGATTCATC
+TCCAATGTCACTTGGACTATCCGATGCGTTTAAGCGAATTGTCGAAGCAC
+TTGCATCTGGATATTTGTATTCTGGTAGGGGGGTTAACATTTAATTTTTT
+TAAAATATTGAAAAATGAGCATATAAAAAGTTTTAAAATAATTCAAATTT
+TTACAAAAAAAAAATTTTTTTTTTCAATTATTTTGCGTTTTTGTATGAAA
+ATTGTGTTTTGAGAACGGAAACTCTTTTTTTTTAATTAAAATTTTGAAAA
+AAAATCCTGGAAAAATGCTGAATTTTTCGGGATTTTTCGGAGCACATTTC
+CAAGCTCTAAAAATTGCTGAAAATTGAATTTTTCAGAATTTTTTTGAATT
+TTGCACAAAAATGACTATTTTAGGAACAAAAAAAACATTTTTCAATCACC
+GAAAAAATGTATTAATTTTATATTTTAATGTTAAAAATACGGTATTTAAA
+TTTTTTTTAAACGTTTTTTTTACACAAAAAGTTGAAATTAGGTTGAACCC
+GGATAAAATTTAGAAAAATTAAAATTTCAATTTTTTTTGCGTTAAAATAT
+GTTTTTTAAGGTTGAAAAAAATATGTTTATTCAAATAAACACATTTCTTG
+AAAAGTTCTTTTGATTTTTAATATTAAAAAATTTATTTTTCAAAAAAAAA
+TTTATTTATTTAATTTTAAAATTTTAAAAACTTTAAATGTGGTGTAGTCG
+ATTTTTTAAATTGTTCTATTAGACTCAAAATTGACTGAAAACACCGAATT
+TCATAATGAAACTTCTTGAAAACTTCTCAAAAAAAAGATATGACTGCTCA
+AAAATGGCCTAAAGTTAGTTAAAATTTGAAATTTGATCTACTTGTCAAGC
+GGCTGGAAACTATTCTTTTTTTTGAAATCACCGTCAAATTTTGAGTATAA
+AATGTAATTATCTTGCGTTATCAACTTGATTTAGGTATTTTAAAGTCGAT
+GGACGGAGAGATTTTTAAAGGTGGAGTACCGAAATTTAAGACTTTGCTTT
+TTTAGACCCAAAATGGCCCAAAACTACCGAATTTCGTAATGAGACGTTCT
+GAAAATTTTCCAAAAAAAAGTTATGGCCGATCAAAGTGTTTGGAAAAAAC
+GGCCTATTTTTAGCTAAAATCTCAAACTTTGGCAATTTTGCAGTGTCGCA
+CCGATAAGTTGCCAAAATTTCGGTCTAAAAAAGCAAAGTCTTAAATTTCG
+GTATTCCACCTTTAAAAGTCTCGCCGTCCATCGACTTTAAAATACCTAAA
+TCAAGTTGATAACGCAAGATAATTACATTTTATACTCAAAATTTGACGGT
+GATTTCAAAAAAGAAAGCTAGTTTCCAGCCGCTTGACAAGTCGGTCAAAT
+TTCAAATTTCCGCTAATATGAGGCCATTTTTTGAGCAATCATAACTTGTT
+TTTTTGAGAACTTTTTTTTTTCAAGAAGTTTCATTATGAAATTCGGTGTT
+TTCAGACAATTTTGAGTCTAATAAAGCAATCAAAAAAATATTCGACTACA
+CCACTTTTTGGCCTATTTTTTTGGCCTAAAATTGAAATTTTTCCAGCAAT
+CCTAAGCGATCCGTGTGAGACGTCTCGTCCGAACGTTCTCGATGCTTTAA
+CCGACGAGCAGAAGCATTCGTTGACCGCCCTGGCACAGAATTTTGTTCGG
+CAAATTGCATTCAATCAGATACATGAGGTATGCGGGGATTTTTCCTGTGC
+AGAAAAAATGTTTAGTAAATTAGGGAAAAAAACCTTGAGTTTTTAAAAAA
+ATCTGTGGAAAATTTGAAAATTTTCGCAAAAAAAAAATTATAATAAAATT
+AATTTCAAATTTGCAAAAATTTCAATTTTTCAAATAAATTTTGAATTTGC
+ATTCCAAAGTCACTAAAATGGAAAAAATTGCTAAAAATTGAATTAAAAAT
+ATTTCTTTCCTGAAAATTTTTTATTTTCCGAGAATTCTGAAATTTCTTTT
+AAAAAAAATTAAATTCGCGAAAATTTGAAATTTTTTGGAATATTGCAAAA
+AATTGCTAAAAATTGAATTTTCCTATATTTCGATTTTTTAGATTTTTTAA
+AAAAGTTTTTTTTCAGCCATTTCTGGCCGAAAATTGAGAAAAAATAGTCA
+GAAAATTCAAAAAATTGCTTTTTTTTTTCAATTTTCCGAAATTTTGAATA
+TTGATCGTCCGAAAATTTAAAAAATAATCGCTAAAAAGTTGAAAAAAAAA
+TTATTGAAAACAATTTTTTTAAAATAATTTCTAGCAGATTCCATGAAAAA
+AGGCTGAAATTTACGAAACAATTTTTTTTTCAAATTCAATTCAGAAAAAA
+TTGAATTTTCTCTGATTTTGGGCCGATATTTATAAGATTTTTCAGAATTT
+TCCAAAAATTCTTGAGAAAAATTGAAATTTTTCTGCCGTATTCCTATGAA
+AACAGCGGAAAATTGAATTTTCCAAGTTATTTTTATAGGGAAAATTATAG
+TGACTCTATAGAATTCATGAAAAATTCTGACAAAAAACCAAACATTTTGG
+CCCAAAATCAGAGAAATTTCACAAAAAAAAATGCTGAAAAATTTAATTTT
+CAGCAATTTTTTTTTCAAATTTTTTTAAAAAATAAATTTTCGTAAATTTC
+ATAATTTTCAGTTTTTTTCCATTTTTTTAAAGAAAAATTATTTTTCCAAA
+AATGTGCAGAAATTTCAGAATTTTCGGAAATTAAAAAAATTTTTAGCAAA
+AAAAAAAATTTTTTAATCCAATTTTTATGATTTTTTCACTTTTTCGGTGG
+TATTAGGACTGCAAATTCAAAGTTTCTTGGAAAAACATAAATTTTCAGAA
+AATTTAAAATTAATCTGATTATAATTCGGAGCATAAAATGTGCTTTTATC
+AACAACATTTTTTTTTTCGAAAAGTCAAATTTTTCCACATTTTTAAAAAT
+TCCTTTTTTTTGTATATATTCGGATTTAAATTTTTTTTTTAACGGGTTTA
+AGCTATTTTCTGAGCAAAAAAATTGAATTTTTCTAAAATCACCATTTTTC
+TTCCAGATTCTCGGAATCGATCGTCTTCAAGACACTATTGATCTACCAGA
+GGATGCTCCGATGCTCAAAAGACCACTGGAGAGCAATGAAAATGCTGAAA
+ACGCAGAAAATCTCGACGATTCGCCAGTTTCCAAAAAGGAGAAGCTCGAC
+GAGGAGCCCGCCGATATTTGAGCATTTTTATTTTAAATTTGGTTTAAATT
+ATTTAATTTTCCTCTAATTTTCCTCATCTCTGTGTTTTTTTCTAATGTTT
+TTGGGTCCCGTAGCGAAAAAACGAATGGCTCTCTTCGCGGTGAGACCTTG
+AAATTTTTATTTTTCTACTATTACCTCCCCCTGCAAACGCGCTCTATTGA
+CGACAATTCGCAATGGAGCGCGATTGCATATTTTGTTACTACATTTTCCA
+CACTCATGTTCGATCTTCCACTAGGGGAGGGTCTCGCAGAAGGATTTTTT
+GAAAAATTTAGATTTTTTTTTGAAAAATATTCGAAACAATTTTACGTTTT
+TCGAAAAAAGTCCTAATTTAGCCTAAAAAATCAAAAATTGATAGGATTTT
+TGAAAAAAATTCAAAAAATCAAAAAAAATTGCAAAAATTTTTATTTTTTT
+TTTTGAAGAAAATTTTTTGTAAAAATTTGATTTTTTTGAAAAAGTTTGAA
+TTTTGAATTTTTTGAAAAATTCTAAAAATTTTGAATTTTTTGAAAAAAAC
+TCAAAATTTTTGGAAAAATTTTGAATTTTTTTGAATAAATTCAGAACTTT
+TTGAAAAAATTCGAATTTTTCTGAAAAAAACTCAAAATTTTTGGAAATAA
+TTGAATTTTTTCGAAAAAATTCGAGAAAATTCCTAATTTAGTCGGAAAAA
+AATATTAAAAATTGATACGATTTTTGAAAAATTTTCCCAAAAATTCTATA
+GAACTGTCCTGAATTTCTAAAAAAAATTCAAAAAAAAAACAAAGTTTTTT
+AGAAATTTGCAAATTTCTTTAAAATTTTGGAAAAAAATCTATTTTTTGTT
+GAAAAGTCTGCAATTTCTAAAATTTTCCTATTTTTTCTGCTAAAACCTGC
+AAAAAAGGACCCTCCCCCTAACTATCTTGTTCCTCCAAAAACCGACAATT
+CTTCTGTTTTTGTGTTATAATCGTCCTTTTTCTTGTTCAACAAAACAAAA
+ATTAAAATAAATTAGAAGAAACGGTAAATTTAGATACGTTTTTGCCACGT
+GGCCGAGGTTTTTCACGGCCACGTGGCAAAGGCCGGCAAGAAATGCGCTG
+TGGTGGGAGAGGAAATTGATAGGGAAGAAGGAAGAAGAAAAAAAAAAGAA
+AAAATCAATATTTTAAAGCCAAAAAAAATTTTTCTGAAAAGACTAGCAAA
+ACAGGAATGGTTATGGGTAAAGCCGAGGTTTTGAAGGAGAATTTTTGGGA
+AAAAAATTGCAAAAAAAAACGAATCGGTAGGGACGGACCGGCAAGATTGA
+TTGAAAAATTGACGAAATTATCGATTTTTTGGCGGCGCACGGGGTTCTGG
+CCTTCCCTCATAAATGGAAGAGTTTTTGCCGAACTAGGCCACCAGGTCAT
+AACTGGGGTAGATTTACGGCGCGTTGCGTGTCGCGTCGCGGCTCAATTTT
+AGTTGTAAAACTAAATGTATTTGTCCGTGTGAAGTACACGACTTTCCCGG
+CGCGCGATTGTCAATGGAGCGCGAAAAATTAAGGGCCAGAAGTCCTCAGA
+ACCCCGTGCAAAAATCGATAATCCCGTTTAGAATCGGTGAGGGCGTGGAA
+AGAAAGAGATGATGAAACGGGAATGAGCAAAATTGCAAAAAAAAACAACA
+AGAAATTCCAGAAAATTCCATAGAAAACGGGGTCTAAAGCACCAGATTAG
+TGTTGTGCGTGGGCGTCCACTGTGACGTCATCACCTTCCACTTTTCGTAG
+TTCGACTCGAGCTGATCGGAGAGCTCGCCGAGCTTGGCGAACTCGGTGAA
+TGTGGCGAATGCTTCGCGGGCGAACATGTCTGTAAAATCAGAAATCAGGA
+GAAAATTCAATTTTGCGCGTCAACTTTGATGTTTTTTTGTGTTGGTGAAC
+TTCAGAAAATTGAATTCGCCAAATTTTACGAGCAAAATTGGGTTCTTTTG
+GTATTTTTCGTGGAAATTTAACCAAAAATCGAGTTTTCTACGGAAATTTA
+ACGTATTTTATCGATTTTTCATCAGAAATCAGTAGAAAATTCCGTTTTGC
+GCGTCAATTTTGATGTATTCGGGTCGGTGAACTGCACCAAACTGGATTCG
+CCAAATTTTACGAGCAAAATGGGGGTTTTTGCAAATTTTTCTTGGAAACT
+CAGTCAAATATTGAATTTTTCGTGGAAATTTAACCAAAAATCGGGCTTGC
+TACGGGAATTTAACAAATTTTATCGAATTTTATTTTGCGCGTCAAATTTG
+ATGTTTTTTGTGTCGGTGAACTTCAGAAAACTGTATTCGCCAAATCTTAC
+GAGCAAAATTGGATTTTTTGGGTATTTTTCGTCCGAAATTGATTTGTCCA
+GTGAAATTAAACGCGATTTATCGATTTTTTATCGGAAATCAGTAGAAAAT
+TCAATTTTGCGCGTCAAATTTGATGTTTTTTGTGTTGGTGAACCTCAAAA
+AACCGTATTCGCCAAATCTTACGAGCAAAATTGTATTTTTTGCGTCTTTT
+TCGTGGAAATTTTTACAAAAATCGTTCTTTTAAAAAAAAAATTCCACACA
+AAAGTACAATTTTCACACAAAAACTGCAATTTGCGCGTAAAATATGGCGC
+AATCGGTTGAGTGCGGCACGCCGACTCAAAAACACCATATTTTACGCGCA
+AATATTAATTGAAGCGCCTTCACGTGGTGTCAGGTTGTGTCATCACGGTT
+TGATCTACAAAAAAATGGGGGAATTTTTTGCCCAATAATATGTGACGTCA
+GCATGTTCTTAGCCATGCAGAATCCGTCTAAAATCCCGCATTTTTTGTAG
+ATCAACGTAGATCAAGCCGAAATGAGACACTCTGGGCTTCAAAACACTCA
+CCAATAAAACCGCATTGTGTGATCGGAACGTTACACGTGTTCCGATCGAA
+TACCTCCATCGTCACAGGCAGCCCTTTCTCTTTTTCTTCTCGAGTCTGGA
+AAATATTGATTTTTATTTTATTCTTGGAATTTTAAATTTCAAACAGTAAA
+AAACCAAAAATTATCAGTTTTAACTTATCCAAGTTAAAGAACTACAGTGA
+AGAGAACTACAGAAATATTAAAAAATATATCGATGCACCAAGAGCCCAAG
+AAATCTCTGAGAGCCCATATCTCGGCTCATTTCGAAGTTACAAATAAACT
+GCAAACTATAAAAATATAGAAAATTAAATTTCAATTATTTTGTTAGTTAA
+CAAAATTTGGCTAGAATTGAAATGAACTGGGATATGGGCTGGCAAAGTTC
+ACTGAATTTTTTCTTTTTTTTTCTTTTGTTTATTTTGATCTCTACACCAG
+GGGTGAGCAGCAAACGATTTTTTCCGGCAAATCGGCAAATCGTTAGCTTG
+CCGGAATAGAAAACTTCCGGCAAATCGGCAAACCGGCAAATTACCGATGT
+GCCGAGTTTGCCGGCAACCGTATGTTCCCTATGAGTATGGCCACCCATCA
+ATCGACTTTGTCGGCTTATATTTCAGCGGTTTCAGAAGTTTTTTGATATT
+TTCAAAAACCAGAGGATAACGATAGATTTGAAAAATATTTTGTCGTTTGA
+ATTTTTAAAATATGATAAAAGACAACCGAGATATAAACGGTCAAAGTCAA
+GGGGGGCCATACAAAAATTTTTTTTTGGAAATTTAGAAAAAAATGTGTTT
+CCGTCTTATTAAAAAAATCTCTCTAAGCATTTCCGGCAAACCGGCAATTG
+CCGCCCTCCCCCGACCTACGCACCTGTTCAAAGTACTCCTCAACAATCCG
+ATGCGCCCATCGCTGACACAATCCCCACTCTCTCGCCGGATTGGAGATGT
+CGGCGCACTTGACAAGCATATCACATATCGTAAGTGAATTCGTGTCACGT
+TGCTCCTCCGGCACATCTGTCACATGCATCTTGTTGAACTTGGCGAGGTA
+CTCAAAGTGTCGACTGATGTCCGTAGCCAACACCATCTCCACCATCGCAT
+GTCGCATTTGGATGAACTCCTCGCGCGACAGACTCGAGAAGATGTTCACG
+TTGGCGTTGTGCTGAAGGGTTAGCTGAAAGGCTAGTGCGATGTGATGATT
+CTCCAGGATCGAGTTATCATTGTAAAGTATTGCAAGCGACTGTCGCGTAT
+TGATCAGGTACGCGTTTCCTCTTCCAGGATGGTCTAGATCATGCACCGCC
+GCTGCGAGAAGAGCCGCCACCGCATGACTTTCATTCACGTGCACGGCGAC
+CGACGGGGAGTCCAGGAAGAATGAGGTGGCCTGTAGGACGTCGGCTGCGT
+GAGTTGCGTTGTGATACGTGTTTCCCGCATGGTAATGAGCCTCGATGGAT
+AGAATCCAACGGTGGAGGAGATCGTCGGAGCAGCCGAGCACATCGCAAAC
+CTTCCACCTCTCGAAGACTTTCATTCCGACTTGGGAAAGAGCGTGGTGAT
+CCGACACCTTTTCCAGATGAAGGATGTCGAATTTCCAGCAATTGTCGTTT
+TCCAGCGCGTTCTTCACGTCAGCAGATACCCGCCGACGTTCTCCATGGGA
+TCCTCGCTTCTCTCGATGCGCGTCGACGACGCTTCGCTTTCGCTGCCTAG
+CTGGATGATGGAGGCGAATGAGACCATCGTAATATTGAGTTGCTATCCGA
+TCGGCGTCGCGGAATCGATTGATCGACGGCGCGTACAGCTCGTGCGACGA
+CAGCACCTTCATCGCGTCCTTTATCGTTTGTGCCGGTTCTCCGTCGACCC
+GTGCCGACACGTCTCGGAGCATTGTGAGCACCTCGGAGATGGGCGCCTCG
+ATGCCGCCCGTCTGCGATTTCAGGCTTTTCAGGGAGACGTCGCGGAAGAT
+TGCGGCGGTGTCACCGGTGGTGTTTGAGCGTTTCATATACACGAATTGAC
+TACTGCAAAATTCATAGAATTTTTTGATTAATTGGTGGCCGAGTTTTTTA
+AAATGGTGGCCGAGATCTTTAAGTTGATGGCAGAGTTTTATAGGTTGATG
+GCCTAGTTTTTTAAAATGGTGACCGAGTTTCTATGCAATTTTGTGGCCGT
+GTTTTTGTATAAGTTGGTGGCCGAATTTTATAAATTGACGGCCGAGTTTT
+ATAGGTTGGTGGTCGAGTTTTATGAATTGGTGGACGAGTTTCTATACAAT
+TTTGTGGCCGAGTTTTTGTATAAGATGGTGGCCGAGTTTTTTCAAAATGA
+TGGCCGCGATCTTTAAGTTGATGGTCGAGTTTTATAAGTTGGTGGCCGAG
+TTTTATAGGTTGATGGCCGAGTTTTTATGTAATTTGGTGGCCGAGTTTTA
+CAAGTTGATGGTCGAGTTTTATGAATTGGTGGCCGAGTTGCTATACAATT
+TTGTGGCCGTGTTTTTATATAATTTGGTGGACGAGTTTTATAAATTGGTG
+GCCGAGTTCTAACGGATTAAGCAAAGGAAACTAGAACAGAATTTTATTGA
+AGAGAAAACTAGGCCATCAGCTTTTCAAGAAAAACTCGGCCACCAAATTT
+TCCAGCAAAAAACTAGGTCGCCAGTTTTTCCAGCAAAAAAACTCGGCCAC
+CAAATTTTCCAGCAAAAAAAACTGGGCCACCAAATTTTCCAGCAAAAAAA
+AAATCGGCCACCAATTTTTCCACGGAAAACTAGGTCATTTCATTGTTCGT
+TTGAGAGAAAGCTAGGTCACGTACATTTTCAATAAGAAAACTCGGCCACC
+AATTTCTTGAGCATAAAAAATTCGGTCATCAATTTTTATAGAGAAAGTTC
+GGCCATCAAGGTTGAAAAATAAGCTAGGCCACCGATTTTTTTTGTTGAAA
+AAAACTCGAACACCTAACCTATTTTCCTTTTTTTTTCAAGCCTAGAAAGC
+TCGGTTATCGAGTTTTTAGGCCACCGATGCATTTTTTTAATCGAAAATCG
+AAAAAAAAAATCGGTGGCCGACTTTTTCATTTACGGCCACCAATTAAAAA
+AAACTCACTTGTTAGCAAACGGGACCCGTATAAATTTCCAGTCGCAACTC
+CGCCGCCGCTCCTCTTCGCCACGTGCCCTCGGCAGGGACTTTCGTCGCAT
+TTCCGATTCGGGTTGTCCGATCACCTCGGATCGTATGCATCCCGTCACGT
+TCTCGTAGGCGCGGTTAACGTACTGCACTACTCGTTGCTCATCACATATT
+TCCACTGCTTGATCCGTCTGAAAATACGCAAAATTTGAAGGTTTGTAGGC
+ACACGTGGCGCCAGTCTATCCCATTACGGTTTGATCTACAAAAAATGCGG
+GAATTTTTCACCCAAAAATATATGACGTCAGCTAGTTCTTAACGATTCTC
+AACTCCCGCATTTTTTGTAGATCTACGTAGATCAAGCCGAAATAAGAGAC
+ACTCTGACACCGCGTGTAGGCAGGTAGGCGTTCAGCCAGGCGATTAGGCA
+GGCAATTAGGCAGGCGATTAGGCAGACTAGTAGGAGGTAGGCAAGTAGGC
+ATGGAGGCCAAAAGCTCACCTCATCCAAGACGGCGAAAAGGGCGGGCAGC
+GCGCGGATCCGATTCGCGAGCCGCCCGACGTAGTCGAAGAGCACCACGTC
+ACGCGTATTCCACGTCACATGCTGAAAAGAAACGAATGAATGGGAATCAG
+TGTGAATGAAATATTAATTAGAATTGAAAATGAGAAAGTGAGAAAACGGA
+TGACTTACATGAATGATGTTGGACTGCGCAAGAGCTCTCCGTCGCTTTTC
+GCTGATGTGTCTGGAATATGTGATTGTTAGATTGACAATTCTGGCAGAGT
+GGTCTAGAAAATTGGGGAAAACTCGGCCACCGATATGTTTTCTTTGGTTG
+TGGTTGGAAAATTTTGGCGACCGAGTTTTTCAACGTATCCAAATTTATGT
+GGCCGTGGCCGACTAAGGCCACATAGAAAAGAAAAATACCGAAACAATTG
+GTGGCCGAGTTTTATCAACGTAGCCTAAATTAGGTGTACTTGGCCGAACT
+TTTCTTCTGACGGCCACGCAGCAAGGAAAAAATAATGAAAAAAAAGTTGG
+TGGCCGAATTTTAAGCCTACACAAAAAGTTGGTGGCCAAATTTTAAGCCA
+ACAAAAATTGGGGGCCGAGTTTTTGTTTTTTGAAAAAATTCGTGGCCGAG
+AAAATGGGAAAACGCGGCCACCGATATTTTTTCTTTGGTTTCTGGCTGAA
+TAATTTTGGTGGCCGAGTTTTTGTTTTGGATAGGTTGGTGGCCGATTTTT
+ATCATTTTAACCTAATTTACGTGTTCTTGGCCGAACTTTTTTCTGACGGC
+CACATAGCAAGGAAAAAATAACGAAAAAAAAGTTGGTGGCCGAATTTTAA
+ATTCACAAGAAAAGTTGGTGGCCGAATTTTAAGCCTACAAAAAGTGGCGG
+CGCTTTTTCTACAAAAAATTGCTGTCATTATTTTAATTGGAAAAACTTGT
+GGCAGTGATTTTGTTTTGAAAAAAATCGTGGCCGAGTTTATCTGTAAAAT
+TGGTGGCCGAGTTTTATTCACGTAACCTAATTTACGTGGCCGTGGCCGAC
+TAAGGCCACATGGCAAAGAAAAATACCGAAACAATTGGTGGCCGAATTTT
+TAGTCTAAAAAAATGGCGGCCGAGTTTTTGTTTAAAAAACCGTATTTAGT
+ATATCTGGGACGAAAAATGGTGGCCGAGGTTTTTCAATGTATCCAAACTT
+ATGTGGCCTTGGCCTATAGCCTAGCTTTCCTAAACCATTTGTTTAAAAAG
+TTGGTGGCCTAGTTTTCCAGCATAATCCAACTCACTTCTCGGCGATCGAC
+ACAATCAACACCTCCTCTGTGCTCACCGATGAGACGTCTCTGAAAAAACG
+TTTCGTTAGTAGATCATGGCTGACGATCAACGCTGCTCCCTTACTTGGCG
+ATTTGCGATGGATGAGGTACTCGAAGATCTATGAATACAGCTAAAGGGCA
+TATTGATTCAACGTCGGATGTTGCCTGCAAGAAAGTGTACATATTCAAAA
+ATTTCCAAAATTCAATTTCCTTTTTCCCGCCCGTGTCCGAATTTCCGGAA
+CTGACCACGTTTCAGTCATGGTCTTCGTAATTCCCAATTTCCTTTCTCCC
+TTATCTTTTTACGTCAATCATGATAGCGGTGATACGTGTTTCGAGGGTAT
+ACATGCTCACACAACAATGCACTTAATCAGCTAATCTCTCCCACACCTCC
+ACAGAGAGAGTGTATGAGCAAGAGAAAGAGCACCTGCTTCTTCCAGATTA
+GTGAGCGAGCCTGTTGTCATCTGACTTCTGCTGACGGAGGGAGCTTGAAA
+AGCGGAGCAGGAAGAGGAGAAGAAAAAGAGCATTCAGAGATAATTACGCG
+CGAGTCGTAGTAGTATGTATACACTGACTTCTTCTTCTTCTTCTTCCTCT
+TTTTCCCCGTCTTCTGCTCGTTGATGTCTGCCATTATATTGATCATTAAC
+GAGGGCCTAAGAATCCTGGAAGAGTTGTGAGGTCACACTGATGGCCTAGG
+AATCTCAAAGGCAGGCCATATCATATTGCAGGCCATATCAGGCCCCATAG
+CCTGGCCATAGTAGGTCACCACAAGCTATGGACTGCCCTCAAGATTTTGG
+CTCAATTTGGATAAGCTTCTTCGGAGCCCCTGGGCTTAACAGACTGACGT
+CATAGGTGGTATATCTCGGCTAGGCGGAAACTCGGAAATGTGAATTTTTT
+GACGCAAACCAAAGATCTTATAGATCCTTGAAATCTTCCACAGGACTTAG
+CAGACCGGAGGCCTGGGAACTATGCAGTTAGAGGTAATCGCCAAGTCCAG
+GGCTCCGAAGAGAGAGGGCCCAGGGCTCCGAAAAAAGCTTAAATTTTGGG
+CCAAAATTTCCCAAATTGGGCCAAAATTTCAAAAGTATGTAGTAGGTTTC
+AACCCTCATATTTCCCGGGATCATGATTTTGTGGACTATTATTTTCAGGC
+TGTGGTGGCCTGCTATACCCAGACTATGTACTGGGCCAAGCTCTGGCCAG
+GTTATGGCCTTTAATAGCCTTGAATTTTGGAGTCAAAGTTCTTGCAGAGC
+CTAGGAGACGCTTACCACTTCGGATCAAAGGCCTGATCTAAAACTCAATG
+GATCATGACCCTAGAACCTCAATTTTCATAAGCCTAATACGCAGCTACTG
+GTCTAAGCTCTGACCAGGCTATATGGCCTGATATGGCCTGAACACTTCGG
+TGGCCTAGTCTAGGTTTTTCCAAGCCCCAGCGGGCCTCAATTTTCATAAG
+CCTAAAGACGCAGCTACTGGGCCAAGCTCTGGCCTTGAATTTTGGAGTCA
+AAGTTATTGCAGAGCCATCATGCCTAGGAGGCCTAATCTAGATTTTTTCA
+AGCATTGAGGCCCCCACGGGCCTCAATTTTCATAAGCCTAAAAACTCAGC
+TGCAGCCTTACCTGTGTTGGAAATGATACTGTACAAATCCATCCGGATGC
+CCGTAACGAGTCGAGGAGCACACTCTCGCCGGTGCCTTCCGTCACGATCA
+CAGCCTGCAAAAAACGCATTATTTATAAGATCTTACAGGGGATTTTCAGG
+ATTTTCAGGAGGATTTTGTCGTGTGCCAGACCTCAAAGCTCGTCGGGATA
+AAATGCTGATATTGATTGACATGCATATATATAGATATATATGAAGTTGG
+AAGAGCGGAAGCAGCAGCAGTGGCAGCAGAACTTGTGTGTGACGGGGATT
+TGTGGGAACAAGGCGCCAAAGAAGACGAAGCAGAAGAAGAAGAAGAAGCC
+GGGGGCAAGCAATGAATGCAATGTATGTAGGAGTATGTAGGAGTATGTGT
+GTGTGTGTGTGTGTGTGCGAAAGTCTCTCTATGTGTGTGTGTGTGTGTCA
+CAGGTTATATATTGCGTGTGCACAAAAAATGTATGAGGTCTCCTGATGTG
+TGTGTGAGTCTGTGAGTCTGTGAGTGCAGTGTACAACACCTTTTGCGGAG
+TCTTATCACATACTGATACGAAAGTGTTTGTATTTTTATATTTCTTTGCC
+ACGTCACACTTTATTCAATTTTTCGCGTGTGCCTCTCGCCCCGTCATTGG
+CACGCAGTAGAAAAAGAAGTAGAAGAAGATGCGTCTTCTTGTTGCCATAT
+CCCATCCAACTTTGTTACTTACGGAATTCGCGCGCGCGCGCGGGGAGGAG
+AAGCAGAAGACGACGACGACGAGCTCGAAAGAAGACGAGTCCGCCTGCGT
+CTCTGCAGTGATCTCGTGTCCCTCGGCAGCGGCTGCGGCGCGCGCTTCAA
+TGAAGACGAGAGCTCCCCCCCCCGGCGGCGCCGAATACGCGATTTGTCAT
+CGAGATGAGCGCTTTGCTGACAGAATAGAATGGGCAAAAACAGGAATACG
+GAATACAGTAGTCATGTTTTGTTGCAATGTTATGGGAAAGCTGGCTTGGC
+GTGGTCGTCGAATTTTTCGCGCTTCATTGACAAAGAACAAGGGAAAGTCG
+TGTTCTCCACACGGACAATCACACTAAGTTTTAGGACTAAAATCGAGCCG
+AGCCAAAATGGCCTAGTTCGGCAGAAACTCTTCCATTTCAATTTGTGAGG
+AAAGCCAGAGTTCTGTGAACCTCGGACCTGCGATCGCCGACCTGCGATCT
+CCTAGACAAATGCTCACCCCAGCGCGGGACTCGGGAAAGTTAGCGCCAGG
+AGAATAATTTTTGAATTTGAAGAAAAAAAAAGAGGAACTTACAGTTTTCA
+GCATCTTCACTTGCATCGGCCCAAACGTGTCATGTGCCGTGGAGCTGCTC
+GTTGCGGCGACAGTTAGCAGAGGTGTTGGTGGAGCACCACGCGATCCACC
+TCCACCACCACCATTCTCAGAATACGACCCACCGCAGCACCATCTCATTG
+CAAACACTGGCCTGGATGCTGCTGCTGCTGTTGCTGCTGGTGCTCTCTGT
+GCGCCTCTTCTAGCTGCGGGCGTGTGCTGCTGCCTCCTGCCAGCTTGACT
+GTGTGCGCTAGCCCCGAGCACACTCTTTTCACCCTCTTCTCCCCCCACCC
+CGCTTCTATCGCCCATTCTCTCAATTCTTCTCTGCCTCCTCCTCCTCCTC
+CTCCTCCTCCCAATTCTCATGTCATCGGGGGGCCCGTCGTGTCGTCGAGC
+GCCCTCTCGCGTCTGCAATGTCTCGGCGCCGCCGCCGTCGTCGTCGTCGT
+CGTCGTCGTCTTCGGGGGGTTGTCATCTGCTGTGTTCACACTGATGCCGC
+CGCCTTCACCGCCCATCTCATCGTCTCCTCCTCTGTGTGGACCCGCCGAC
+CGGCCGGCGCGCCTTCTCCCATCAGTTCTATCTCTCTCTCTCACTCACTT
+ACTCTCAAACCGCGTCAATTGATCTCTCTGGCACGCTCTTCGCTCGGCGA
+GCTGTATTCGGTGTCGGTTTTCAGTCTGCGTCTCCGCGCCCCGGTGCAAT
+GCATATGTTCCATCACGTTCTGCTCCTCTTGTTGCTCCGTGTGCTGCCGT
+GTTTTACGCAATTTCAGGTAAAATTGATACAATTGATACAATTGATAATT
+ATCGAAGTGTCCTCTATGTGTACTCACGCTGTTAATTTAATGGCCTAACC
+ACAGAATTATGCTTCTTTAATTTTTGAACTCGTAGCTCCGTATGTTAAAT
+CCACTATGAGATTCCTTGCCATGTTTTTGCAATATTTTTTTGTTTGTTAT
+GAGAAAGTGTATGTGTTCTTTGTTTGGTCACATGGGAACCGCTGGCCTGA
+GAATGGAAGGTTTTCTGGGACAGAGCTTTTGAATCCGATAGCCTACAATA
+GGGCCCCAGTGCAATAACGGTAGGCAGGCCCGAGGCCTAATTTAGTCCAA
+ATAGTCCTTATTCAGTCTAGATGATTCAAAGCTAAAATCAAAGGGCTGTT
+CCATTACGTTGTGATCTACAAAAAATGCGGGAATTTTTCGCCCTAAAAAT
+GTGACGTCATCACGTTCCATGCGTTATTATTTATGAAGTCTGCGTCTCAT
+TCTCCCGCATTTTTTGAAGATCTACGTAGATCAACCAAGCGCCTTACCCC
+TAGCCTCTAAGCTCCTAGGGCCCTCTAGGACCATTTAGGCTTTTTGGACT
+GTCTAAGACCAATTGGGCTTTTAGGCTCCTAGGTCCCTCAAGGACCGTTA
+GGCCTCTTGGACTATCTGAAACCATCTGGGCGTCTAGGCTCCTAGGGCCC
+TATAGGACTATTTAGGCCTCTTGGACTATCTAAGACCATCTAGACTTCTA
+GGCCTCTAGGGCTCTCTAGGACCATTTTGACTTGTTCTATAGGACCTTGT
+TCGACTAGCTAAGACCATCTGGGCTTCTAGGCTTCTAGGGCTCTCTAGGA
+CCATTTAGGCCTCTTGGACTATCTAAGACTAATTGGGCTTCGAAGCTCCT
+AGAGCCCTCTAGGACCATTTAGGCCTCTTGGACGATCTAAGATCATCTGG
+GCTTCTAGGCTTCTAGGCCCCTCTAGGACCTTCTAAGACCCCAGTCTTTA
+TTCCCTAGCCTCTAGGCTCATAGGCCTCGATTCCGCAATTCTAATGGCTT
+TGGGAGCCCAGTTCTAAGGCCCATGGACTTCCACAGTAGCTTTTCAGTCA
+ACCATTTCCAAGTTAACCAAGGACCATTTAAGCCTTTTGGGCTATCTAAG
+ACCATCTGGGCGTTTACTTTCTAGGCCTTTTCCTGCCTATTGGGCCCTCT
+TGGACCTTCTAAGACCCTGGCCTTTAATCCCTAGCCTCTAATCCTCTAGG
+CCTCGATTCCGCAAATACAATCCCAGTTCTAGACTCTCAGGGCCCTTGGG
+CTTGTAGGCTTTCAGTTAACCATTTCAAACAGGTGCCGTTCCGCTCCATC
+TCTTCTTGCTCTCTCGTGCTCCTCTCCTACACCATCTTCTCTCATTGTTC
+TGACGGATGGATGAGCTGTCATCATCATCATCAAAGCTCCAAAGACAATT
+GCCATCAATTTGTGCCGCCGCTGTGCTAAGTGGTCTTATTCCGCCGGGAC
+AAAAAAAAAGGGAAAATTCTCTGGGAATTTGGACTAACACCACCTACTAT
+TACTGTAAAAAAACATTTGGAGAAGGGGGAAACGAACTAAAAAAAAACAA
+ATTAAAATCGGCGTATCAAATTGAAATCATATGATTCGTTGCCGTCGTCT
+TCTCTGCAATGATCGTTTGTTCCGTCGTGTCAAACTAACCTACTCAATGT
+CATAAAGAACAAAGAATGAATTCAATAAAACAAGACGAAAAAATAAATAC
+ATTCAGGTACTGTACAGAGAGAATCAGGATCACATCTGGAATAGCTCGCA
+GCCTGTTCGATTCTGGGAGCTTGTTGAGTATAGGCCGACCACTACGCCGC
+CGCCGACCACTACGACAGAGTATATACCGCCACCGACGACTACGTATGTT
+CCCTGAACTTTAAAGTTGCATTTTTTTTTAAAGGATTAGGGGTTTTAATT
+GAAATTTCAGAATTTTTGGTAAATTTTTTAAAATTAGTTTTATTTTTTTA
+CGGGCTTTTGCGATTATTACTGGTAGAATGAAAGTATGTACATTTCTTGT
+AGATCAGAAAATTTAATTTTTGATATCCGATAAATGTTAAAAACTCGATC
+GAAAAAAAAATAAATTTTTCCAAAAACTAAAAAGTTGCAAAATTTATTTT
+TTTTACAATTCAAAGTTTGTAATTTTTGACAAAATACATTCAGAAATTTT
+TTTGGAATAGGGGTTTTAATTAGGCTTGGGCCTAGGTTTGGGCTTGGGCT
+TGGGCTCAGGCTTAGGCTTATGGTTAGGCTTAGGCTTAGGATTGGGCTTA
+GGCTTAGGCTTGTGCTGAAGCTTGGGCTTGGGCTTAGGCTTCAGCTTAGG
+CTCAGGCTTAGGCTTGTGCTGAGGCTTGGGCTTAGGCTTAGGCTCTCAGG
+CTTAGGCTTGGGCTTGGGCTTGGGTATGGACTTAAAATTTTTTTTCAAAA
+ATTTTATTTTTCGAAAACTTATGGTTTTACCGGTATAAAGTGCCTTTTTT
+TGTACATAAAAAATAATTTTTAAATTTTTTAACGTTCCTAAAAACTAAAC
+AAACTGTAAAGAAAATTTTGTTTAAAAAAAAAATCAATAAAACATATTTT
+CAGTAATTTCCAAAATTTGATTTCCCGGTAAAAATCAACAATTTTTTATC
+GGGGCCACAAAAAAAATTCGCTGAAAAAAATTCAATTGGATGTATTTTCT
+GCAAATTCGAGTCAATTTTCTGAAAATAGTTGTTTATTTTCCCTGATTTT
+TTGGCGTTTTTTCCTTTTTTAAAGGAATTTTAGGACTTTCTGGGATTTAG
+AAGGGTTTAGCCTAGGGAGTGATTAAGCCTAGGCTTAAGCCTGAACCTGA
+GCCTAAGCCTAAACCTAAGCCTAAGCCTAAGCCTAAGCCTAACATCAAAA
+AAACCGGAAAATCCTAAGCCTAAATAGCGTCAGTAGCAAGCTGACGCTCG
+CCACTGACACCAAGCCTAAGCCTCAGCCTTTAACGAAAAACAATTTTGGC
+ACAAAAATTGCAAAATTTCCGCTTCTCCGCTTCTCTTAAGACATTGAATT
+TCCAAATTTAAAAATTTTTAGAAAAAAAAAAACCTCGGTCCAAAATGATC
+TGAAAATTCTTATTTAGGCTTTAAAAAATTTCACTTTTTTCTGCGACACT
+TTCCATAACACCACAAATTCGGCGAATCGACCTGTTGATGATCTTGTCTC
+GACCCGCTCTCTCTCTAAGTGATTATAACAGAGATACACCCACACACCCA
+CACACGTCATCTATTATGTTCTAGAACTTTATACTTTATGATCAAAACCG
+AATGCTACAAACTAAAAAAACATCACCACTTTTTCCAAATTTTCGTCACA
+TTTTTGCAGTCCGACCACAACTACAACCACCAAAGATCCATGTGAATCAT
+CGCATCCGTTGGATCTGACGCGTCGGCTACGGGACACTGCCGGCTACAAT
+CGTATCTATATGGCCAGCGACTTTTCGTCGGCTCGCAATGAGTTTCCTGA
+TCTCAGGGGTTTGGCTCACAAAGCTTCAACGGACTATCATTGCGGGAAGA
+GGTGCCAACGGTGAGCTCTCAATGCCTACCTGCCTACTTGTTTGCAGTAT
+CAAACATATAATGCCTACAAGCCTACGCGCCTACCTTGGTCTACGAGCCT
+GAACTTGCACATTTTCTGTGCCTAACATGCACGCTATACTTTTGTCTGCC
+GTTACGCGCCCCCCCCCCCCGCCTATCTGCCTACAAGTCTCCCTTTTGTC
+TTTATGCCTACGCGCCTATCACATGCCTACCTGCCTATTTGCTTGCGGTC
+GAGTCGATACATATCATGCCTACGAGCCTACGCGCCTACCTTGGGCTACT
+AGCCTGAATTCGCATTTTTCCAGTGCCTAGCTTGCGCGCTATACCTATGC
+CTGCATTTACGCGCCTTCTCCCCGCCTAGCTGCCTACAATCGCACTTTCT
+GCCTACCTGCATGCTTTCCTACCTATTCGCATACTTAGGCGTACCTACCA
+CAAGCTTAGCTACCTACAAAACTGCCTTCTGCCAACCTGCATGACTGCGT
+ACCTTTTCGCCTGCTTAGGTGCCTACCACAAGCCTCCCTTTTGTCGATAT
+TCCTACGCGCCTATGGCATACCTACATGCCTACTTGTTTGAGTCGATACA
+TATCATGCCTACGCGCCTACCTTGGCCTACCTTGGCCTACAATCCTGAAA
+TTGCACTTTTCCTGTGCCTAGCTTGTACACTATACTTATGCCTGCCTTTA
+CGCGCCTTCTCCGCGCTTATCTGCCTACAAGCATACCTTCTGCCTCCTTG
+CATGCCTACATACCTATTAGCCTGCTTACGCGAACCTACCACAAGCCTAG
+CTGCCTACAAACCTCCCTTCTGCCTATATGCCTACGCACCTAACTCCTGC
+CTGCCTATACGTCTACCTCATGCTGAAAACAGACCTGCCTTGTACCTACC
+TATGCGCCTACCTAAGATTTGCCTCCTACGTGCCTGGCTGCCTATTTTGC
+CTATAGGCATTACTGTCAGTGCGTCTACCCAGAGCCTACCTTTAGGTAGA
+CGTTTGCCTACCTAAAGCAACCGCCTACAAGTCTATTCGCCTGCCTCCTT
+GCCTACCTACACACCTCCCTTATCCCGGCTTTTCCACCTGCCTATGCGCC
+TATCTCATGCCTACCCAAGACCTGCAAACGTGCCTAGCCGTATGCCTACC
+TAACTTCGCGCCTACATATGCCTCCCTTTCAGATCGAGTCAACTAATTCG
+AAAAATCATAAAAACCGGCCAACCGGCAGAAGCCGAACGTGCTTGGTGGG
+ACGAGGAAGAGTGGGAGGAGGGCGAGAGACGCAGGAAACGAGCCATCGAA
+TGGAAGGATACAGATGATCGTCTGCTAATGCGAAATACCGGAACATCACG
+TCATATTTTGGGTAGGTAGGTGGGTGAACACAGCAAGTGCGCTCCATCGC
+GCGGGACACTTTTCCCGCGCTTTTTAGGAGGTCAAACACGGAATTTTTCC
+AGGAATGACTGTGGCGGTGGAATGCGATGATGAGACTGGAGAATTTAATA
+GTGGTGGATACTCGTTGTGTACTACGTGCCGTGCTGTTCGACACTTGCCA
+TCCACGTATTTTCCACGTGTCATTAATGAGCTGATTTGCTCGCAGAAAGC
+GTGTTTGCGAGGAGAAGGAAAATGCATACAACGGGTTATGCCGATGAAGG
+TATGTAATTTTTTTGTTTTTGCAATGGAGCGCGTTTGTACTCACTCCACG
+AGAATCACGTGGTGTCAGAGTGTCTCATTTCGGATTGATCTACAAAAAAT
+GCGGGAGAAGAGACACAGAGTTCTCAACTGATTTTGGATGATTAAGAACG
+TGCTGACGACACATTTTTATGGGCAAAAAATTCCCGCATTTTTTGTAGAT
+CAAATCACTTGGAGAATATTATTTTTATTTGAATATGATCCTTTAAAGAA
+AAAATAAAATTTGACTGAATTTCCCGCCAAAAAATTTTCGCAGAAAATTT
+AAATTTCCCGGCAAAATATTCACGGATATCTGGCTTCCCTCATAAATTGA
+AATGGAAGAGTTTTTGCCGAACTAGGCCAGGCCATATCTGGGGTAGATTT
+ACGGCGCGTTGCGTGTCGCGTCGCGGCTCGATTTTAGTTGTAAAACTAAA
+TATATTTGTCCGTGTGGAGTACACGACTTTCCCACGCGTTGGTGATTGTC
+AATAGAGTGCGAAAAATTCAATGAGGAAGGCCAGAACCCCGTGAATATTT
+TCTCAAACATTTTTTTTGGAATTAATGTGCAATCGCGCTCTAACGCAGTA
+TCCAAAACTTGGGTCTTTTGGCGGGAAACCCGAAAATTCAAAGTTTTTTG
+CTTTAAAATATCGTGAAACAGACGAAACTAGTCGCAAAATTTCAAATTTA
+CGGTCTTGCCGCGCCAGTGCGGTGGATCACGATTGCACTTAAGAAAAATG
+GCGAAAATCAAAAATTTGGTTTATTTTTGGCAACTATTTTTCATTCTCTA
+TCAAATTCATACTGTACACGTGGAAAATCATTGATTTTCCCGAAAATTTG
+AATAAATGGGATGCAAGATGCGAGCGCGCCCTATTGTGATTCGTTAAAAT
+TCGTTAGAAGCGTCACTGAAATCGAAATTTTTTCTCGAAAAATTGCAGTG
+TGCCACGTTGTAAAATATCGATTTTTTGGAAAATTTAATATTTAGAAGTG
+CGGATGCATCCTATTGTGCTCCAATAAAATTACACGGGCTTCTGGCATTC
+CGCATTGAATTTTTCGCGCTCCATTGACAATCGCCCGTGTACTCCACACG
+GACAAGTGCATTTAGTTTTAAAACTAAAATCGAGCCGCGACGCGACACGC
+AACGCGCCGTAAATCTACCCCAGATATGGCCTGGCCTAGTTCGGCAAAAA
+CTCTTCCATTTCAAAATATGAGGAAGGCCAGAACCTCGTGGAAAATATCG
+ATTTTTCCATTTCCACGTGGCCAAAGGAATTGCAAGCGCGCTCCAGTGAA
+CTCGCCCAATTTCCATTTTTTTTCAGGTTCTCCGAAACGTGGGCACCCGC
+GAGTGTGCTCGCTGGCAAATGAGCCAAATCGACGTGCGAACGTGTTGTGA
+TTGTATGCTCAATCCGTCATCACCACTGGTCACCTATTTATGAGCGAAAA
+AACCGGGGAAAAAAACACACAAAACAACTCAAAACTCAACAAAAAAAAAT
+AATTTTACAAGATTCAACGAAACAACAAAAAAAAGAAACAATGGAAATTA
+AATACGGATGCTGCTGCCAAATATGCTGCCAAATTCAAATTCTCGCCTTG
+TACACACGATCTTTATTGAAAACGGTGATCAACGGGCACCCTCCACTCTG
+ACCTTTTATCTGAAAATAATTGTTTTAAAGATTTATTTGATTAAAAACCT
+CGGCCACGGCCGCGACGCAGCCGCTCCGCACGCAGCTGCGTCGCGGTCGG
+GTGGATCCTAACCTGAACTTCTCCCTCCAGCTCGTTATCGTCGTCGACCA
+CCTCGAACAGTTTGCTAGCCTCGAATAGAAATCTGAAAAAAATAAATTGG
+TTTTTTTTGAAAATATATAATGTTTTATGTTTGGGCTTCTGGCCTTCCTC
+ATTGCATTTTTCGCGCGCTCCATTGACAATCGCCCCCCTGTGTACTCCAC
+ACGGACAAATCACATTTAGTTTCACAACGAACGACACGCAACGCGCCTGG
+CCTAGTTCGGCAGAAAAACTCTTCCATTTCAATTTATGAGGGAAGCCAGA
+AATCCGCGTGTGTTTTATTGATTTTATTGATTTTTTTACTTTCGAAAATC
+GCGTTCCGGCTGGTAGAAGCACAAGGTTTTGCGCGTGTCGGCGATTCGAT
+CCCTCGACCATTCTCTGCAAAAAAAATATTTTTTTTTGTGTAAAATTCCC
+AATCTGCGAGAACGGGATCTACGAAAAATTTTTTTTTTAATATTTTAATG
+ATTTTTTCAGAGATCACATTCTTGCAGATCATCTTTTCGTGGGGCCTCCT
+AATTTTTCAGTGCTGCACATTTATTTAACATTCAAAAGTGCTTTTTTCAT
+AAAAATTTGAATTTTTTGCCCAAAAATCGAGAAAAACGCCGCTCCGCCTC
+TTTTTCCGTGCGGCACTGTGCCTTTTGCAAGCTGGGCACAGTTTTGTAGG
+CGTGAGCATGGTCTTACTTGAGCGCTTGAGTGATCTACGAAAAAAAAAAA
+GCTTTTTTTAAAATTTATGTCGGAGATCACATTCTTGCAGATCATCTTTT
+CGTGGGGCCTGCTTATTTTTCAGTGCCGCTCGGAAAAAGAGGCGGAGCGT
+CGTGAGGCACGGTTTTTTGTCACGATTTTACAGTTTTTTGACTAAAATTC
+TTGATTTTGGATCATTTTCGTTGATTTTTTTCGGAAAAAGCTGATTTTGG
+CAAAAAAAAAATTTTCGCTTTTTTTTGGACAAAGAAGAGCCAAAAAAAAA
+AATGAAAAAATCATAAATTTTTTAGTTTTTACATTTTTTTTTTTGAATTG
+AAAAATGTTTTTTTGTGTTTTTGGTGAAAAAAACTACTTTTTTTTGCGAA
+AAAAAAATAGCAAAAATGACCAAAAATCGGAAAAAAAAAACGCCGCTCCG
+CCTCTTTTTCCGTGCGGCACTTCGCCATTTGCAAGCTGGGCACGGTTTTG
+TAGGCGTTGTCATGTTGTCATTACTTGAGCGCTTTGAGGCAAAGACTTAT
+GGGAGAACGGTGAAATCCAAAATTGGTGGCGTTCGGGAAGAGACGGGGGT
+GCTTCTGAAAAAAATTGTTGAAAAATGCAAAAAATCTGAAATTTTAGAGC
+ATTTTTCTGAAAAAAATGCAAAAAATCCGAAATTTTTGAGCATTTTTCTG
+AAAAAAACGCTAAAAATCTGAAATTTTAGAGCATTTTTCTGAAAAAAACG
+CTAAAAATCTTAAATTTCTGAGCATTTTTCCCGGAAAAAAAAAGATTTTT
+ATGCACCTCTGCGAAAACTTCATCCATCATGGTAATTGAAAAATCACAAC
+TGTCCAAAAGCACCGAATTCACAGTGTCGAGCTCGAAAACGCCGACATCT
+TCGACCTAAAATGCTCAATTTTAATGGGGAAAAGCTCTAAAATCATGGGC
+TTCTCGCATTCCTCGTTGAATTGTTCGCGCTCCATTGACAATCGCCCCCG
+TGTACTCCACACGGACAAGTGCATTTAGTTTTAAAACTAAAATCGAGCCG
+CGACGCGACACGCAACGCGCCGTAAATCTACGAAAAAAAAAAGGAATTTT
+TGCTGAAAAATCGATAAAACACGTTAAATTTAACCAGAAAAATCAATTTT
+CGCACAAAAATTCGCAAAAAAAAAAAATCAAATTTTGCTCATAAAATTTG
+GCGATTTCAGTTTTCTGAGGTTCACCGACCCAAAAAACGTCAAATTTGAC
+GCGCAAAACTTGAATTTTCTATTGATTTTTGATGAAAAATCGATAAAATA
+CGGTCAATTTAACCAGAAAAATCAATTTTTAACGAGAAAAGCCAGAAATC
+CGTTGAAAAAGCTCTAAAAATCAAAATACAAACATTCGAGAGAGTCAGAT
+GACGGAGACAGACGCATTTTTTCAGAATTTTCTGCAAATTTAGGTCCAAA
+CTGACGAAATAGAAGACACGGAGCACACTGGAAATGAAAAAAAATTAATT
+AAATGCTAGATTTTTAGCATTTTTTCAGAAAAAATGCACTAAAATTTCAG
+ATTTTTAGCATTTTTTTCCGGAAAAATACACTGAAATTTCAGATTTTTAT
+TTATTTTTTTTTGAAAAAATGCTACAGACCGAATAGTTTGCCAGGCATTT
+CTGCCGCGGAGGAAATCGGCGATGAACTCTGCCACGTAGCGGCATTCGAT
+GGGCGGTGGCTGAAAATTTGCAATTTTTTGGCCTAAAATTTGGTTTTTTC
+TGGAAAATTCTCTTACCAACGGGAAGGTTTTCGTCTTCGGAATGCCTAAA
+TTAACAATACAAGCCCTCGGAGCAATTCTCGCAAGAATTGGAGCCAGCTC
+CTTGGCATAAGTGAGATCATAGATGAAGAAGACGAGCCGCTTCACCATTA
+CGATGCTCTTGCAGCGTTCACGGCGTTCTGCGTATTTTTCCAGGATACTC
+TGAAAAAAAATCCGTTAATTTTAGCCAAAAAATCCGTTAAATTTAGCCAA
+AAAATCCGTTAATTTTAGCCAAAAAATCCGTTAATTTTAGCCAAAAAATC
+CGTTAATTTTAGCCAAAAAATCCGTTAACTTTAGCCAAAAAATCCGTTAA
+TTTTAGCCAAAAAATCCGTTAATTTTAGCCAAAAAATCCGTTATTTTAAG
+TCAAAAAATCCGTTATTTTAGCCAAAAAATTCGTTAATTTTAGCCAAAAA
+TTCGCTAGTTTCAGCCAAAAAAATCCGTTAATTTTAGCCAAAAAAGAACC
+GTTATTTTTAGCCAAAAAATCCTTTAATTTTAGCCAAAAATTCGATATTT
+TTAGCAAAAAAAATCCGTTAATTTTAGGCAAAGAACCGTTAATTTTAGCC
+AAAAAATCCGTTAATTTAAGTCAAAAAATCCGTTAATTTTAGCCAAAAAA
+ATCCGTTAATTTAAGTCAAAAAATCCGTTATTTTAGCCAAAAAATTCGTT
+AATTTTAGCCAAAAATTCGCTAGTTTCAGCCAAAAAAATCCGTTAATTTT
+AGCCAAAAAAGAACCGTTATTTTTAGCCAAAAAATCCGTTAATTTTAGCC
+AAAAATTCGATATTTTTAGCAAAAAGAATCCGTTAATTTTAGCCAAAAAT
+CCGTTAATTTTAGCCAAAAATCCGTTAATTTTAGCCAAAAATTCGATATT
+TTTAGCAAAAAAAATCCGTTAATTTTAGGCAAAGAACCGTTAATTTTAGC
+CAAAAAATCCGTTAATTTTAGCCAAAAAAATCCGTTAATTTAAGTCAAAA
+AATCCGTTAATTTTAGCCAAAAAAATCCGTTAATTTAAGTCAAAAAATCC
+GTTAATTTTAGCCAAAAAAGAACCGTTATTTTTAGCCAAAAAATCCGTTA
+ATTTTAGCCAAAAATTCGATATTTTTAGCCAAAAATCCGTTAATTTTAGC
+CAAAAATCCGTTAATTTTAGCCAAAAATTCGATATTTTTAGCAAAAAAAA
+TCCGTTAATTTTAGGCAAAGAACCGTTAATTTTAGCCAAAAAATCCGTTA
+ATTTTAGCCAAAAAAATCCGTTAATTTAAGTCAAAAAATCCGTTAATTTT
+AGCCAAAAAAATCCGTTAATTTAAGTCAAAAAATCCGTTAATTTAAGTCA
+AAAAATCCGTTAATTTTAGCCAAAAAAGAACCGTTATTTTTAGCCAAAAA
+ATCCGTTAATTTTAGCCAAAAATTCGATATTTTTAGCAAAAAGAATCCGT
+TAATTTTAGCCAAAAATCCGTTAATTTTAGCCAAAAATCCGTTAATTTTA
+GCCAAAAATTCGATATTTTTAGCAAAAAAAATCCGTTAATTTTAGGCAAA
+GAACCGTTAATTTTAGCCAAAAATTCGATATTTTTAGCCAAAAAATCCAT
+TAATTTTAGCCAAAAATTGCTAATTTTAGCAAAAAAATTCGCTATTTTTA
+GCCAAAAAATCCGTTAATTTTAGCCAAAAAATTCGCTATTTTTAGCCAAA
+AAACTGTTAATTTTAGCCAAAAATCCGTTGATTTTAGCCAAACAATTAGT
+TATTTTTAGCCAAAAAATCCGTAAATTTTAGCCAAAAAATCTGTTATTTT
+TAGTCAAAAAATTCGTGAATTTTAACCGGAAAATCCGTTATTTTTACTAC
+AAAAATAGCGAATTTTCGCCAATTTTAACCAAAATCTCTCGATTTTTTGT
+CAAAAATGCACCAAATGTGCGCTTTTTTTCGTTTTTTTTTGGCATTTTCC
+CTACTTCAATAGCGAGTTTGCAGGTCGTCGTGCAAATTTTGACTTCGATT
+TCAACAGAATCCAGCAGAATTCGATCATCAGTCATACATTCCAAACAATT
+TTCAGCATCCTTTATGGGCACTTCGATGAAATCTGAGAGAGCAAACACTT
+TAGAATTGCCAGGGTTTACAGCTCTTTTAATCACCATCCAACTGGCACGC
+GACGTCCATTTTTGGCTGCCCATTCACCCGCTCGCCGCCACCCTTGCAAA
+TGTTGTGAAATTTGATGACAAACGGTTCAGAGTACTCGAAATTCTCCAGA
+TCGCCGTGCTCGACGAGCTCGTTGTTCGATGGTGCTCTTTCCGGCGTTCT
+TTTCCATCTGAAACTGCTGTTTTTCCTTTTTTTTTTTGTCGCAAAATCTT
+TTTTTTCACCGAATTTTTCCACCAACCTGAACAGCGAATCTTCGAAAAGA
+GACGAAGAATTCGATTTTGGGCTTTCCAAATTTGAAAAATTCAAAGAAGT
+TGTCACAGAACTAGCCATTTCGAAGTTGAAATGATTAAAAATCAAAAACA
+AAAAATTTCGATAAAAATCAATGTCCGAGAGGAGTACACGCTTGGGAACC
+ATGCGCGGGTCTCGCACGGAAGAGACGAATTGAAGTACGGTAGCTCGTAA
+ATCCTGTTCCACGATTGATTTTTTTTTAATTTTTGATCAATTTTTTCGAT
+TTTATCCCAGAAGTTCTTGAAAATTATCCGTTTTTTTGCAATTTTTTCGG
+AAAAATGCTCTAAAATTTAAGATTTTTAGCATTTTTTTCCGAAAAAAATG
+TTTTAAAATTGCAGATTTTTAGCATTTTTTCACAAAAAATGCACTAAAAT
+TAAGATTCTTAGCATTTTTGCGGAAAAAATGCTAAAAATCTTGCAAAGAC
+TGAAAAAATTCGAATTTGTTGTAATATTGCATGTTTTCCGAGGTTTTACA
+TCAAATATGTGTAGTTTTCCTTGAAATTTGACGTTTTTCACTGAAAAATT
+CTACAAAAATAAGCATTTCTGAGCTCTTTTGTCGCAAAAGTTGATGAAAA
+TCGCCAATTTTTCAATAAATATTGCACAGAAACCGTCAGATTTTTAGCAT
+TTTTTCGGAAAAATGCACTAAAATTTTAGATTATTAGCAATTTTTCAGAA
+AAATGCTCTAAAATTTAAGATTTTTAGCCCTTTTTTTCAGAAAAATTCAC
+TAAAATGCAAGATTTTAATCATTTTTTTGCAAGAAAAATGCTCTAAAATC
+TAAGTTTTTTAGCATTTTTTTCGGAAAAATGTTTGAAAATCCCTTCTTTA
+ACGCCTTTTTCGCACTAAAAGATGCTCAAACTAGTTTAAACTTTCAGAGT
+TTTCCCATGCTTTTGCCCCCTCCACTTCACAAGAAACAAGAAACAAATAC
+GGCGGGAAAAAAGCGAAAATTCGCGGAAAACATCATTTTCAATGCATTTT
+TCATCGCGAAAATTGCCGAATTTCATTAAAAATGGCCAATTTTTGTGCCA
+GTTTTCCCAATTAATCATGTATTTTCGATTAACTCGAAGCCCCTGCGCAG
+AGAAAAACACAAAAATGTTGCAATTGTTTGTGTAAAGCACTTCTCTGCGC
+GTCTGCGGCATCCGATATGACGAGCAATATATATCTTTTTTCTGGGAGCC
+TTTTATTTTAAATTTATCATTTTTCATTTAGTTTTTGAGAAAAAAATTCC
+CCCAAAATTAACCTAAAAGCCTTGAAAATGTGAATTTTGAGTGAAATTTG
+ACGTTTTTCAGCGAAAAATTCTCAATTTTTAGTGCATTTTTGCCGGAAAA
+ATGCTAATAATCTTGAATTTTAGTGCTTAGCGGAAAAAAAATTCAAAATG
+AAAATGTCGAATTTGAAATAAAATGCTTTAAAATTTAAGATTTTTAGCAT
+TTTTCCCGAGAAAAGCTAAAAATCTTAATTTTTATAGCTTTTTTGTTGAA
+AAAATGCTAAAAATCTTAAATTTTAGATCATTTTATTTCAAATTCGACAT
+TTTCATTTTGTATTTAAGAAAAAATAACCTCAAAGTCTGAAAAATATCGA
+ATTTTGAGTGAAATTTGACATTTTTCAGCGAAAAATTCTCATTTTTCCGG
+AAAAAATGCTAAAAATCTTGAATTTTAGTGCATTTTTCCAGAAAAAATGC
+TAAAAATCTCAATTTTTAGTGCATTTTCCCGGAAAAATGCTAAAAATCTT
+AAATTTTAGAGCATTTTCCAGAAAAAATGCTTAAAATCTTGAATTTCAGA
+GCATTCTTAATGAAAAATGCTAAAAATCTTAAATTTTAGAGCATTTTTCT
+CGAAAAAATGCTTAAAATCTTGAATTTCAGAGCATTTTTTTCGGAAAAAT
+GCTAAAAATCTCAATTTTTAGTGCATTTTTCTGAAAAAATACTAAAAATC
+TTGAATTTTTAGAGCATTTTCGCTGAAAAATAATAAAAATTTTAAATTTT
+AGAGCATTTTTCCGAAAAAAAAAACGCTAAAAATCTTGTAATAACTGACA
+AATTTCGAATTTTGAGTAAAATGGCATGTTTTTTGAGGTTTTTCCTTGAA
+ATTTGACGTTTTTCACCTAAAAATTCGACAAAAATGAGCATTTCTGAGCT
+CTTATATTGCAAAAATTGACAAAAATCGTCAATTTTTCAATAAAAATTGC
+CCAAAAACCTTAAAATATTCTGAAAAAAGCCGAAAAAACCCCATTTTTTA
+GCCATTTTCTACAGAATTTTACATTTTTCTCAACTTTCTTCACCTAAAAT
+CGCCGATATTATTCACATAAAATTCCCTTTTTTTTCAGCGCAATGGGGTG
+TATTATGAGCCAGGAGGATGAAGCAGCGAAACGAAGATCCAAGAAGATTG
+ATCGATTGGTAAAAATTGGGGATTTTTCGTTGAAAAAACTCGATTTTTTG
+TGAAAAAATATAGAAAAATCATCAAAACTGCTTCAAAAACCGAAAAATTT
+CACTAAAAACTAGAATTTTTGCTCGAAAACCTCAAAAAATCGCAAAATTT
+GCAGTGAAAACTAGATTTTTATTTTTAAAAAATTCAAAAAGTTCATAAAA
+ATCAATAAAAAAATCGGATTTTTTTTCTTAAAAAATCTGGAAAACTGTCT
+AAAAATCTACTCAAAATCAGTTTTTTTTGTAGAAAATCTGAAAAATAGTC
+TAAAAAATTAATAAAAATCGATTTTTTGGGAGAAAATTTGAAAAATTACG
+AAAAAAATCAATAAAAAATCGGTTTTTTGGGAAAAACCCTGAAAAATTGT
+CTAAAAATCTATAAAAAATTGGATTTTTTAAATAGAAAATCTGAAAAACT
+GCCAAAAAATCAACAAAAAATCGATTTTTGTGTGAGAAAACCTGAAAAAT
+TATCAAAAAATTGGTTTTTATCTAGAAAATCTGAAAAATTACCTAAAAAG
+CAATAAAAAATCGGTTTTTTTTCTGGAAAAACTGTAAAATAGCCTAAAAA
+TCAATTTAAAAAAAGTTTTTTTTTTTGTAGAAAACCTGAAAAATTATCAA
+TAAAAACCACGAAAAACAGTTTTTCGCTTATAAAAAGTCCAAAAATCCCA
+AAATTTGCATTAAAAACTAGATTTTTATTTCAAAAAAATTCAAAAATTGC
+CTGAAAATCAATAAAATTGTTGTTTTTTTTTGGAAAAAAAAACCCTGAAA
+AATTGGCTAAAAATCCCAAATTTTTTTGCAGCTCAAAGAAGACGGCGAGA
+ACTCAATGCGAACCATCAAGCTTCTGCTCCTGGGAGCCGGCGAGTCTGGA
+AAATCGACGATTTTAAAGCAGATGCGTATCATTCACGACGTCGGATATAC
+GACTGAAGAGAGAAAAGTGTTCAGAGGCGTCGTTTATGGAAATATTATTT
+TGGTCAGTGCTCCGATGCACTGAAAAATGACAGGAAATTGGCAATTTTGA
+CCAAAATTCGTGGATTTTAACCAAAAAATCCGTTAATTTTAATCAAAAAT
+CGGCTAATTTTAGCCAAAAAATTCGCTATTTTAACCAAAAAATCCGTTGA
+TTTTAGTCAAAAAATTCGCTATTTTTAGCCAAAAAATCGCTATTTTTAGC
+CAAAAAATCCGTTAATTTTAGCCAAAAATTTCGCTATTTTTAGCCAAAAA
+ATCCGTTAATTTTAGGCAAAAAATCCGTTAATTTTAGTCAAAAAATCCGC
+TATTTTAACCAAAAAATCCGCTATTTTAACCAAAAAATCCGTTAATTTTA
+GCCAAAAAATTCGCTATTTTTAGCCAAAAAATCCGTTAATTTTAGCCAAA
+AAATTCGCTATTTTTAGCCAAAAAATCCGTTAATTTTAGCCAAAAAATTC
+GCTATTTTTAGCCAAAAAATCCGTTAATTTTAGCCAAAAAATTCGCTATT
+TTTAGCCAAAAAATTCGCTATTTTTAGCCAAAAAATCCGTTAATTTTAGC
+CAAAAAATTCGCTATTTTTAGCCAAAAAATTCACCAATTTTCGTTTAAGA
+TTCTCCAATTTTTGACAAAAAAATTCACCGAATTTGCTCAAAATTCTCCC
+TTTTTTGGCTAAAAAATGCATAAATTACACAATTAAACCAAAAATTACCC
+AATTTCGCCCAAAAACTCTAATTTTTACCAAAAATTCTCCTATTTTTTGT
+TGAAAATTCACCAATTTTTTTGCCAAATTTTAACAGAAAAATCTATAAAA
+TATCAGGCGAAAATAACCTAATTTTGGTCAAAAATTCACCGATTTTTGTT
+CAAAATTCTTCAATTTTACCCAATATCCACCAAATTTTAACCAAAAAAGT
+CTAAAAAATTATTCAAAAAATCCCTAATTTTGGCCCAAAATTCTCCATTT
+TTACTCAAAAATTCTCTCTTTTTAACCAAAAAATCTAGAATATTAGGTGA
+AAAATGCCTAATTTTGGCTAAAAATTCACCGATTTTTGACAAAAAAAACC
+TCCAATTTCAGCTTAAAACTCTCTGATTTTTACCAAAAAAATCTAAAATA
+TTAGGCGAAAAATCACTAATTTCGGCTAAAAAATCACCAATTTTTGACAA
+AAGAAACTCCAATTCCAACAAAAAATTCACAAAATTTACTCAAAAATTGT
+CTGTTTTTCACAAAAAAAAAACCTACAATATTAGGAGAAAATTCACAAAT
+TTTGGCCAAAAAATCCCTAATTTTGGCCGAAAAATTTGCCAATTTTGTTC
+AAAATTCTCCAATTTTCGACTAAAAAAACCTGCCATATTCAGCAAAAAGT
+TCACCAAATTTACTCAAAAATTCAAAAAAAATCTAGAATATTAGGCGAAA
+AATCCCTAATTTTGTCCAAAAATTCACCGATTTTTGACAAAAAAAACTCT
+AATTTCAGCAGAAACTTCACCAAATCATAGCCAAAAATTCACTGTTTTTT
+ACCAAAAAAATAGAATATTAAGAGAAAATCCCTAAATTTGTCCAAAAAAT
+TAAACAAATTATAGCCAAAAATGCTCTGTTTTTTACCAAAAATTCTAGAA
+TATTAGGTAAAAAATCCCTAATTTTTCCCAAAAAATTCACCGAATTTACT
+CCAAAATGCTCTGTTTTTGACAAAAAAAAACTCTAATTCCAGCACAAAAT
+TTACCAAATTATAGCCAAAAATGCTCTTTTTTTTCCAAAAAAAATCTAAA
+ATATTAGGCGAAAAATCCCTAATTTTGTCCAAAAATTCACCGATTTTTGA
+CAAAAAAAACTCTAATTTCAGCAGAAACTTCACCAAATCATAGCCAAAAA
+TTCACTGTTTTTTACCAAAAAAATAGAATATTAAGAGAAAATCCCTAAAT
+TTGTCCAAAAAATTAAACAAATTATAGCCAAAAATGCTCTGTTTTTTACC
+AAAAATTCTAGAATATTAGGTAAAAAATCCCTAATTTTTCCCAAAAAATT
+CACCGAATTTACTCCAAAATGCTCTGTTTTTGACAAAAAAAAACTCTAAT
+TCCAGCACAAAATTTACCAAATTATAGCCAAAAATGCTCTTTTTTTTCCA
+AAAAAAATCTAAAATATTAGGCGAAAAATCCCTAATTTTGGCCAAAAAAA
+TTACACCAATTTTCCCCAATTTCAGCTTAAAATGTTCAATTTCTAACCAA
+AAAACCCCCAAATTTTAACCCAAAAATTCCCTCGAATTTCACCCCAAAAC
+CGTCCAATTTTCCAGTCTCTCAACGCCATCATCCACGCTATGGAGCAGTT
+AAAAATCAGCTTCACCACACTCGATCACGAATCAGATGCCCGAAAGCTTC
+TAATGTTCAGCACAACAGGCGAAGAGGATGAGCTGCCCGAAGAGCTCGTC
+GTGCTCATGAAGAGTGTTTGGTCCGATTCGGGAATTCAGAAAGCGCTCGA
+AAGGTGGCGAAATTTCGCTGAAAATTGAGAAAATTCGAGGGATTTTCGCT
+GAAAATCGAGAAATTTCGGTGGAAATTAGCTTATTTCCATGAAAAAATCG
+TTAAAATCCCAGAAAATTGCGATTTTGGACTATTTTTGAGCATTTTTCGC
+GTTTTTTCCATGAAAAATTCAATGAAATCGATTTTTTAGGTCATATTCGC
+TGAAAATTACCGCTTTTTTCGATGAAAAATTCGTTGATATTCGTTGAAAA
+TTATCTATTAGAGCTAATTAAAATTTAAAATTCCAAAAAAAAAAATATTT
+TAAAATAATCAATCGAATTATTTTTTGCTCACACTTTCAAAAACCGCTAA
+AAATTCTAAAAAAAAAATTTTGGAGCCCCTTTTCCGCTAGAAAATAGCTT
+TTTTTCCCTCAAAATCCGGGAAAATTCAGAAATATTTAATTTTTTGGCTA
+TTTCTGACTCTTATTCCCACACAAAAATAGTTTTACCAAAAAAAAACAAT
+TTTTGTCAAAAATTCGAAAAAAAAATTTCTGGGAAATATTTTTAAATGAC
+TCTAAATTTTCCCCTGTACCCGAATATCGATGTGAAAAAATTCAGAAAAA
+TTTTCCGCGATTTTATATGATTTTTTGAAAATTGGACAAATTTCAGTTTT
+CCCCCCTAATTCCTATTTGAGTTACCGCCAATTTGATTTGTTCGATGGAC
+TTGCACATTTTTGAATTAATCTATTTTATTTTTTGTTGTTTTTTCCACCG
+ATTTTTAATGTTTTCGGTGTATTTTTGCTTGAATTTTAGGGGAAAAGTCA
+AAATAAATGCAATTTTCGATTAAAAAGCACGCTGACCGGCGTAAAAATGA
+AAAAGTAACGATTTTAAACGATTTCAAACCTGAATTAATTAATTTCACTG
+ATTTACGCCTGTACGCGTGCGTAGATCAGTGAAATTAATTAATTTAGGTT
+CGAAATCGTTTAAAAGCGTTACTTTTTCATTTTTACGCCTGTAAGCGTGC
+TTTTTAATCAGAAATTTGCAATTATTTTGACTTTTTCTCTAAAATTCAAG
+CAAAAATACACCGAAAACATCAAAAATCGGTGGAAAATAACAAAAAATAA
+AATAAATAAATTTAAAATTGTGCAAGCGCGCTCCATCGAACAAATCCAAT
+TGGCGGTAATTCAAATAGGAATTAGGCAAAAACTGAGATTTTTGAGGCAC
+CACGTTTTGAAGATCTGTTCAAAAAGAAGATCTACGTTTTCAGGATCTGG
+CACCGTGCCAACTGCGGTTTTCTCGATGAAAAACGTAACAACGATGCTCC
+GATGTTACGCGTCGCGTGTTGTTTTGCGTTCAGAAAGATATTTTTTGAAA
+TTTTCTTCTTGAAGAAACGCTTAACGACACGCAACGCGTAACATCGGAGC
+ATCGTTGTTACGTTTTTCATCGAGAAAACCGCAGTTGGCACGGTGTCAGA
+TCCTGAAAACGTAGATCTTCTTTTCGTAGATTTTCAGAATGTAGATCTTC
+TTTTGGTAAATCTTCTTTTCGTAGATCTTCTTTTCGTCGATCTTCAAAAT
+GTAGATCTTCTTTTGGTAGATCTTCTTTTCGTAGATCTTCTTTTCGTAGA
+TCTTCTTTTTCGTAGATCTTCTTTTTGAACAGATCTTCAAAACGTGGTGC
+CTCTGATTTTTCCAAATTTCAAAAAATCATATAAAATTTAGAAAATTTTT
+TTGAATTTGTTTATCAGCATATTTGGTCATTTTGGTACCATATTTTCCCC
+TGATTCCGAATATCAATGTGAAAAAATTCAAAAAAAAAATCCCTGATTTT
+ATATTTAAGCTTGAAATCGCCGAATGAGATTTTTCAAATACGCGCGCACA
+AATAAATTCTCCTTGGAGCGCGTTTGCCTCATTTGATTTTCTCCATATTT
+ATTTTTACTTTTTTTTCAGTTTTTCACAGCTATTTTCATTCATTTTTATT
+GTATTTTATAGGTTTTTTTTTTTGAAAAATAAATTTTTCCGTGTGAATTG
+AACATTTTATTTGCATAAAAATGAATGAAAATAGCTGAAAAACTGAATAA
+AGTAAAAATAAATATGGAGAAAATTAAATGAGGCAAACGTGCACCAAGGA
+TAATTTATTTGGGCGCGTATTTGAAAAATCTCATGTAGGAGGCAAATGAA
+ATTTAGGCGATTTCTAGCTTAAATATAATATCAGGGAAATTTTTTTTTTG
+ATTTTTTCACATCGATATTCGAATCAGGGGAAAATTTGGAGCCACCTGTA
+ACAAAATTTTATGAAAAAAAAAACTGTATAATTTCTAACAACTTTTTTTT
+TGTAGATCACGCGAATATCAGCTCAACGATTCGGCCGGCTACTATCTGAG
+CCAACTCGACAGAATTTGTGCTCCTAATTACATTCCCACACAGGTATTTT
+TCACTGGAAAATTCACAAATTTTTCCACTACTAAAAATTCAAATTTCCTT
+TGCAGGATGACATTCTCCGCACAAGAATCAAGACAACAGGAATCGTGGAG
+ACGCAGTTTGTCTACAAAGATCGCCTATTTTTGTAGGGGGAAAATTAATT
+TTAAAAAATTGAAAAAATCGTCGCCGAAATTCAGGGTTTTCGACGTTGGC
+GGACAGCGATCCGAACGAAAAAAGTGGATTCATTGCTTCGAAGACGTGAC
+GGCACTCATTTTCTGCGTTGCACTGTCAGAATATGATATGGTTCTTGTCG
+AAGATTGTCAGACGGTGCGATTTTCGAGTTTTTTGCTTTTTTTTCGTTTT
+TTTCCCAAGTTTAGGGTTTTTCGGTGAAAATCTCGGTTTTCTTGGTTAAA
+ATGGTTTTTTTTTTGGCAAAAAACGGCAAAAATTGAGGATTTTAGCGTAT
+TTTGGCGAAAAATTGAGTTAATTACATGGAAAATTTCAGAATTTGAGTTA
+AAATTGTAGTTTAAGGATTTTTTAGTGATTTTCTCGATTTTTGAACCGAA
+AAACGTTCGAATTTCATTTATTACGCGCGACCACAAAATGCTGAGAACGC
+GTATTGCACAACATATTTGACGCGCAAAATATCTCGTAGCGAAAACTAAA
+GTAATTCTATAAATGACTACTGTAGCGCTCTTGTGTCGATTTACGGAAAT
+CGTGTATTAATCGATAAAGTATTTTTTTTAGAAACACAAAAATGACAAAA
+AAAATACGAAAGAAAATTGAATTGTTTCGAAAATCGAGTCCTCCCGTAAA
+TCGACACAGTTGCCATTAAATTAAATAAAATTAATGTTAACTGTGTCGAT
+TTACGGGAGGACTCTCGATTTTCGAAACAATTCAATTTTCTTTCGTTTTT
+TTTTGTCATTTTTGTGTTTCTAAAAAAAATACTTTATCGATTAATACACG
+ATTTCCGTAAATCGACCCACAAGAGCTACAGTAGTCATTTTCAGAACTAC
+TGTAGTTTTCGCTACGAGATATAATTGCGCATCAAATATGTTGTGCATGA
+CGGATTCTCAGCATTTTGTGGTCGCGCGTAATGAAAAGCGAAAAAATCGA
+TATTTTCTGATTTTTGCGCCGAATTTTGTTAATTTTTCTTTTTTTTTTTT
+CTGCGAAAACCACATTTTCCTGACTAAATTCAGGTTCAGCCATTTTTTTT
+CGCAAAAATCGACGAAAATTGAGAATTTTAGCGTACTTTTAATTTTTTTA
+AATTTTTTTCGCTCTGAAAATTATGAAAAAATCAAAATTTTCTCGATTTT
+TGAACCGAAAAACGTTCAAATTTCATTTAAAAATCGAAAAAATCGGGAAA
+AAATTTTCCGATTTTTGCACCGATGATTTTCGCTAATTTTTCACCACATT
+TTTTGCGTTTCAGAATCGAATGCGAGAATCGCTAAAACTGTTCGACTCGA
+TTTGCAACAATAAATGGTTTGTCGAGACGTCGATTATTCTATTTCTCAAC
+AAAAAAGACTTATTCGAAGAGAAAATCGTTCGATCTCCACTCACACACTG
+CTTTCCGGAATATACGGGCGCCAATAATTACGAAGAAGCTTCTGCGTACA
+TTCAACAACAGTTTGAGGATATGAATAAGAGGACTACTGGAGAGAAAGTT
+GGTGGTTTTTTTGAATTCACTGCAACTTTTTCCTCACGAGGGACGAGGAA
+AAGTGGTTTCTAGGTCATGGCCGAGGGGCCGACAAGTTTCAGCGGCCATT
+TATCTTGCTTTGTTTTCCGCCTGTTTTCTTTCGTTTTTCATCGATTTTTT
+TCGTTTTTTCGTAATAAAACTGATAAATAAATATTTTTTGCAGATGCTAA
+AACAATTTCCAAGTAAAAAAATCATGTATTCAGTCGGCAAGCAGCGATGA
+AAGTGGGCATTGTAATATGATGGATTACGGGAATACAAAACCTAAACTTT
+TTCTGAAACATGAAACATATGATGCTTAGATGCTGAAATTACCTGATTTT
+CATAACGAGACCGCTGAAAAGTTTTGAGGTTTCCACAATTCAACTTTTTG
+TGCGAAAATCTCGACTTTTTCACCAAAAAAGTTGAATTTTGGAAACCTCA
+AAACTTTTCAGCGGTCTCGTTATGAAAATCAGGTAGTTTCAGCATTTAAG
+CAGCATATGTATCATGTTTCAGAAAAAGTTTAGGTTTTGTATTCCCGTAA
+TCCATCATATTGCATTGCCCTTGTTTCACCGCTGCTTGCCCACTGAATGC
+ATAATTTTTTTACTTGGAAATTGATTTAGCATCTGCAAAAAATATTTATT
+CATCAGTTTTATTAAGAAAAACGAAAAAAATCGATGAAAAACGAAAGAAA
+ACAGGCGGAAAACAAAGCAAGATAAATGGCCGCTGAAACTTGTCGGCCCC
+TCGGCCATGGCCTAGAAACCACTTTTCCTCGTCCCTCGTGAGGAAAAAGT
+TGCAGTGAGAAAACTCAATTTTTGAATTTTTTTTTCATGAAAATCGGAAA
+ATCTTCAATTTTTCCTAATCAATTCCATCTCTACAGAATCAAGAAATCTA
+CACCCAATTCACATGTGCCACCGACACTAACAACATTCGATTCGTTTTCG
+ATGCCGTCACCGACATTATCATTCGAGATAACCTCCGCACGTGCGGGCTC
+TACTAAATTTTTCCGCTAAATTTTAAATTCCGTTTTTTCCCCCCAAAATC
+CCCTCCCAGACATTTTCCGGTATTTATGTATTGACCACACACAACTCTTC
+TCTCCCGTCTCCGCTGTTCAATGCTACGGTTATTCTCTTTTTTTTTCTTT
+TTTTTTCCTGAAATTCCAAGGGTGTCGTTGAAAATCGAAAAATTCGAAAA
+ATTTGGGTTTTTTAGAGGAAAAGCCAAAAATTCAATTTTTTTTTCGATTT
+TTATTCCGGAAAATTCGAAAAATTTCGATATTTTTTAAATTTTTTACAAA
+AAATTCGAAAAATTTGGATTTTTTCAGGAAAAAGCCAAAAAATTACAATT
+TGTGTTTAAAAAAACGAAAAAAAAAACCAATTTTTCTGATTTTAATTCCG
+GAAAAATCAAAAAATCTCGATTATTTTCAGAAAAATTCGAAAAATTTGGG
+GCTTTTTCCAAAAAAGAAATCGTAAAATTTCGATTTTGTCCAGGAAAAAT
+CGAAAATTTAATGTTTTCTTTTTTGGCTTCTTCCGGAAAATCCAAAAATT
+TTGAATTTTTTGGATTTGTTTTCAGAAAAATTGGAAAAATTTGGATTTTT
+CAGGAAAAAGCCTAACAATTTCAAATTTTGCTTTAAAAAAACTTTAAAAA
+ATTGATTTTTGAGGAAAAAACGAAAAATTTCGACATTTTTTGATTTTTTT
+TTTACCGAAAAAAAAATTGATTTTTTCCAGGAAAAAGCCAAAAATTTTCA
+ATTTTTAAGGAAAAATTCGAACAATTTTGATTTATTGATTTTTTATTACG
+GAAAAATCGAAAAATTTGGGTTTTTTAGAGTGAAAAGCCAAAAGTTCAAT
+TTATTTTTCTGGAGAAATCCAATTATTTCAATTTTTGAATTTTTTCAAGA
+AAAATAAAAAAATGTCGATTTTTTCCAGAAAAATCGAAATTTTTCGTTTT
+TGAATGAAAAAAAATTTTTCCTTCAATTTTTCCTTTAAAAAAAATAAATA
+AAAATGTTCGAATTTCCATGAAAAAAAGTCAAAAAAATTCAAAATTTTCC
+ATTTTCCCTGACAAAAAAATCAAAATTTTCCGATTTTCCTAAACCAAAAT
+CCCAAAATTTTCTGATTTTCCAATTTTCTCTGAAAAATCGAATTTTTTGC
+CGCACACCCCTGGTTTCACGTGGTGGTCAGGTTGTCTCATTGCGGTTTGT
+GATCTACAAAAAATGAGGGAATCTTTCCTCCCCCGGGAAAATCTGACGTC
+AGCGCACTCGTGTAACCATGCGAAATCCTCTGCTGAAAAGTCTGCGTCTC
+TTCTCCCGCATTTTTTGTAGATCAACGTGTAGATCAATCCAAAATGACAC
+CTTGACACCACGTGCCTAAGCCCAAGCCTAAACCAATCCATTTTACCGGT
+ATATCTCTACAACCTTTCACTGTCTGAAATATCGCGTCATTTTATATTAT
+TATTATTATTGTATTCGCTTAAACGACAACAATTCCCCCATTTGATTCAA
+AAAGTAAACATTTCCGAACTTTTTAAAAATTTGAAAAATATTTTTAAAAA
+ATTTTAGCGTGAAAAACTTGTCCCCCCACCCTGCCTCTCCAAAAAAAATT
+AATTTCGGAAGAATTCAGTCCTTGTTTTTGTAAATTGAGAACGTAATGCG
+CTTTTTGGTGGTTTTTGCATATTTATCGACACTTGCGTACGCGAGGTATC
+GATTCAGATTCCGTGAGTTTTTTACAACAAAATATCGCTAAGCAATCGCG
+CTCCAGCGCGAAACTTCAAAAAAAGGCCAAAATTTTGCGTCGCTTTCTAT
+GATTTTAAGACGAAAAGCGAGGAAAAATCAATAAAAACAGCGAAAACTTT
+GAAATTTACGGGTTTGCCGCTTTTTTTGCGCTAGAGCGCGATTGCTCACT
+GAGTTCAAGCGCCCTTCTTATTTTGAAATGGAAGAGTTTGCCGAATTAGG
+CTATTTTGGTGCGGCCACGGCTGGGGTCAATTTACGGCGCGTTGCGTGCC
+GCGTCGCGGTTAGGTGGACCACGCCTTTCCCACGCGTAGACGATTGTCAA
+TAGAGCGCCGAAAATGCAAGGCCAGAAGCCCGTATGAGTGAAGTTTTTGT
+TCATTTTCACTTTTTTTTCGTCGTTTTTAACGGTTTTTATGTGAAAATCA
+ATAAAAACGGCGAAAATAATTAAAAATTTTCGATATTCCGGGTTTGGCGC
+TTGCTTTGCGCTAGAGCGCGATTGGTCACCGAGTTCAAACGGCGCACTCT
+GGCTTCCCTCTTAATTTGAAATGGAAGAGTTTGCCGAATTAGGCCATTTT
+GGGTCGGCGGGTAGATTTACGGCGCGTCGCGTGTCGCCTCGCGGCTCGAT
+TTTGATTGTAAAACTAAATGTATTTGTCCGTGTGGAGTACACGCGACTTT
+CCCACGCGTTGTCCAGCAGGTTATTGCCAATGGAGCGCCGAAAATGCAAG
+GCCAGAAGCCCGCCGTATAAGTAGCCCATATGAGTGAAGTTTTTGTACAT
+TTTCACTTTTTGTTTCGTCGTTTTTATGGTTTTTATGTGAAAATCCACAG
+TCTCCTCGTCATCGAAAGCGCACAAAAAACTGCTTACTGGCGCGTTTCGC
+GTTTTTGCTAGCGCATTTTGTGGATTTCTCCGAAATTCAGAAATTACGCG
+GAAAATAGGCTAGAATTCCAAAATTACAGCCCCGCCTCTTTTGATAATTA
+TCTTCAGGATGAAGAAGATGATCGCGAAGGTGGGTGACTTGAAATATACA
+AGAAAAATATGATTTCTTCAGAGAAACACCATTTTTACCGTTGATTTTTT
+AATATCCCTACTCCTCCTTCAGTTTTTGACCAAATTTTCTCTTTTAATGG
+TCTTTCATTTCATTTTGTGCTAATAAACAAATGTTAAGTTCGAAATCTGC
+GAAAAAATTCGTTTCAACGCTAAAAAACGACGAAGTTTATTTTTCAACAC
+TAAAAAGATTCACTCCCTCCCCCGGCTGTGCCAATGTGCAAGTGCGCCCC
+AGCCCAATTCGACGCCGAGGAGACTGTGAAATCATTAAAAACAGTGAAAA
+TAACGGAAAATTTCTGAAATTCCGGGTTTGCCGTTTTTTTTTGCGCTGGA
+GCGCGATTGCTCACCGATTTCAAATAGCGCACGCGCTTCTGGTTTCCCCC
+ATAAATTGAAATGGAAGAGTTTTCGCCGAACTAGGTCATTTTGGCGCGGC
+CACGACCGGGGTAGATTTACGGCGCGCTACGTGTCGCGTCGCGGATCGAT
+TTTAGTTGTAAAACTAAATGTAGTTGTCCGTGTGGAGTACACGACTCTCC
+CGTCCGGCAGGCGATTGCCAATGGAGCGCGAAAATGCGAGGCCAGAAGCC
+CGTGCATTTTTTTGCGGGTCCCGCCACGACATTTACCCTTTCAGACACGT
+GTATCAAAGAGGACCAGGCGATTTTGGAGAAGGAAAATGTGAACTCGCCA
+CGCCAATTTCTTTTTATCGATGACGGACAATCGCCAAAGTGGAGGGAAAA
+TGATCTCGAAGGAAAAGGAATTCTTATGAGCTTCGGAAATCGATTGAAGA
+ATCTGACAAACGGATATGAGACTGTGAGACTTTTTTTACGGGTCTCGACG
+CGATTTCCCACGGATTTCGGGCTTCCCTCATAAATTGAAATGGAAGAGTT
+TTTGCCGAACTAGGCCCCGGCCATATCTGGGGTAGATTTACGGCGCGTTG
+CGTGTCGCGTCGCGGCTCGATTTTAGTTGTAAAACTGAATGTATTTGTCC
+GTGTGGAGTACACGGGCGATTGCCAATGGAGCGCGAAAAATTCAATTTGT
+GTCTCGTAACGATTTTATCGATTCTTTTTCAGGGTGCCGAACAAGCTCTG
+CGTGTCCTTGAATTCAACAATACGGAACACTTTCTTGTGATCAATTTTTG
+GATGAGAAGCTACTATTTCATGAAAAACGGTGATAAATATCAGCTGTCAT
+ACACCGGAACCACCATCAAACCCGATTTGAATCACTTTATTCGGTTAGCA
+GGCTTGGAGATGCAATATCGCTCCATCGCAACCATTTTTTCAGCGTATAC
+TTCATCTGCGCTCCAGCGAACAGTCAGAGTGCGTTGATCGTGTTTGGGGA
+TCAGTCGAAACCGCGAGTTTTAAAGTCGAAAAAATCGAAGAGGGAAGCAG
+CGCTGATTGATGAGAATTCGGGGAAGAAGCTGAAAAAGTGCCAGAAAATT
+CGGACGAAAAGAGCGGCGGCGGTGAATAACTCGACGGAGTGGACACAGAC
+GCTGAAGGATACTCGGAGACTTAAACAACGTAGCGAGTGAGTTTGTGCCA
+AACGATACTCCGATGTTCCGCTTCCGCTGAGGACACCGCGTCGTTTGATC
+TCTGAAAATTGCGAGAGTCAGCCTCGTGTAAGTTTACCGCAAATTTGGAG
+GTCAAGCAGCGAGGTCCTCATATTTTGAAATGGAAGAGCTTGCCGAATTC
+GGAGTCGATTTACGGCGCGTTGCGTTGCGTGTCGCGTCGCGGCTCGTGAT
+TTTCGCATATTTATCGACACTTGCGTACGCCAGGTATCGATTCAGATTCC
+GTGAGTTTTTGCAACAAAAAAATCGCTGAGCAATCGCGCTCCACTGGAAA
+ACACCCGAAAAGTTTTGAAATTCCGGGGTTGCCGCTTGTTTTGCGCGCTA
+GAGCGCGATTGCTCGCCGAGTTCAAACGGCGCTCTCTGGTTTCCCTCTTG
+TACGAGACGAGCGTCGCGGTTCGGTCCAGCAGGCGATTGTCAATGGAGCG
+CGAAAAACACGTGGTGTCAAAGTCTCCAATTATGGTTTGATCTTTGATAA
+ATGCGGGAGACGAGAGACACCGACTTCTCAACTGATTTCGCATGGTTAAA
+AGTGTTCTGACGTCACATTTTTCTGGAAGAAAAACTCCCGCATTTTTTGT
+AAATCAAACCGGATTAGGACAGCCGGACACCACGTGGAAAAACAAGATGA
+GGGAAGCCACAGAAGCCCGTGCAGAGTCTCGGTTTTATCAGTTTTCGAGT
+AGTTTCGCACCACAAAAAGCGTGTGACGTCACATTTTTCCGGCCGCAAAA
+TTCCCGCGTTTTTTGAAGATCAAACCGAAATGCATTGTTTCAGAATCTAC
+TCTTGGGCACGTCTCTCGTTCATTCACCTCGGTTTCGGTATGGTAGTGAT
+CGTCAACGCCATCGTTTTTTTGTTCTTTTTCAAGTATTTCAAGAAGTTCA
+ACTCGACGGTGAAGAATGGAGATCAGAAGCAGGAATCGGATGAGACTGAT
+GAGAAGACTGAGAAGACTGAGAAGCAGGCGAAATAGAACTTTTTAGTCTA
+TCTGTGTTGAAATAAAGGAATTGAAAAAAAAAAAAAAAAAAATTTTTTTG
+CATATATGCATGTGGTGTCAGAGTGGATTATTTCGGTTTGATCTACGTTG
+ATCTACAAAAAATGCGGGAACTGATTTTGCATGGTTAAGAACGTGCTGAC
+GTCACATATTTTTTGGGCGAAAATTCCGGCATTTTTTGTAGATCAAACCG
+TGATGGGACGTCTGGCATCACGTGTACATGTAGAAATGAGATACAACATG
+TTATGTACCGTTATCCTACAGTACTATAGGTGAACCCCTCAATTTTTGAC
+CTCCAAAAATTGCGGGAATCTTATAGGTCAACTTGCAGGGGGTCGTGGAC
+ATGAATAAGCCAAATTCAAATTATTCAAGCCAAAAAGATGATAGCGCAGA
+CACGTGCCCCCAATTTCGGTTTGATCTACTGTGTAGATCTACAAAAAATG
+CGGGATTTAGGACGCTGAGTTCTCCACTGATTTTGCAACAAATTCCCGCT
+TTTTTGAAGATCAAACCGGACAACCTGACACCACGTGAAGGAATAAACCA
+CGCTCTTTTGCCAAAATCTTAAGAGTTTCTACAATTTCAGTGAAAATCCA
+GTATTAGATTTGATATTTGAAAAAAAAAAGTTAAATAATGGACGCGGCCT
+AGTCTTTCCTCTTCTACTAGCAAAACGCCCTGTTTTACAAAAAAAATCTA
+TAGTTTCTGAAAAAAAAATCAGTGGCAAATGTCTACAATTTTCAATATTT
+CATACTAAAAAAATCACAAAAAATTATTTTATGGCCGCGGTCGAGTTTTT
+TACTCTTCCACGTGGTTTCAGAGTGTCCAATTTCGGTTTGATCTACCGTG
+TAGATCTACAAAAAATTCGGGAGTCGAGAACTGATTTTGCATGATTGCTG
+ACGTCACATTGTTTTGGGTAAAAAATTCCCGCATTTTTTGTAGATCAAAC
+CGGACAGCCTGGCACCGCGTGCGCAGAGAAGAAAAAGCTAATGAGCACGC
+GGTGTCAGGCACGGCTTGATCTACAAAAATTGCGGGAATTTTCAACCCAA
+AAATATGTGACGTCAGCGCGTGCTTAACCATGCAGAATCAGTTCTCAACT
+CCCGCATTTTTTGTAGATCTACGTAGATCAAACCGAAATGGGACACTCTG
+ACACCACGTGAATGAGCCAATTGAGCAAAAATCGTACTGAAAGAGATCGT
+TTTATTCGCGCAGAGGTTAGTTACACGAATTGAATAGAAAAAATAATGTT
+TTGCAAAAAAAAAGTAATGTACATACTCATGGAAATAAATTTATTATGGG
+GGAGCTTGATTATTACAAGTCGACGAAGAGCAGCACTCCTTCTTCTCCTC
+CTTTTCCTTCTCTTTTTCCTTTGGAAGCTGCGGAGAATTCGACTCGGATT
+TCGACATTAGACGGGAGCTGGAGCATCTGAAAAAAAAACGCGAAAAATGG
+TAGATCACACGTTTTCCAACCTATTACCTTCTCAAACTAAGACTGGAGAA
+GAGCGGTGTACACTTGAGCATGTCCTTCAACTGTATCGACTCGTAGTTTT
+CGATCGATTCCTGGAACTTTTCGATCCACAGCTCCTTGTCCGCCTTGTCG
+GCGGCTTGTAGGGTGTAGATGCCGACGACTTGGTAGTAGCGGGTTAGGTG
+AATTATGACGAACGCGAATTTTAGGGACACTGGAAGAGGAACACACTTAT
+AGTGACACTACAGTAGTCCTAGAAGGTATTGGTAAGGTACTGGTAAGGTA
+CTGACTGCGCTAATTTTTGTACGTTACACATTTTCCTGGAGTTTTGCAGA
+CCTTCAAGAAAATTCTAGCACTTTCCAGATTTTCTCCGAAAAATTCCTGC
+ACTTTCCAGATTTTTCCAGAGAATTCCTGCACTTTACAGATTTTTCTAGA
+AAATTTTGTTTTTCTCAGAGTTTTTCCTATAACTACAGTAATCCTACAGT
+ACCCCGACCATATCGCCCCTACCAACATACAACCCAATATTCCATCAAAA
+GACAAAAACTCAAATTTTCCCGAACTACAGTAACCCTACAGTAACTCTAC
+CGTATACCTACCGGGCCCCTACAGTACTGCTGCAGTACCTTGACATTATC
+CCCTACCAACATACAACCCAATACCTCTTCGAAAGCTGGGAACTCAAATT
+TTCTATAACTACAGTAATCCTACAGTACTTCTACAGTACCTCTACAGTAC
+TACTACAGTACACCGACCATATCCCCCACTAACCCTAAACCAATATTCCT
+TCAAAAGACAAAAACTCAAATTTTCCCAAACTACAGTAAGCCTACAGTAC
+TCCTACAGTCCCCCGACCATATCCCCCTACCAACATACAGCCCAATATTC
+CATCAAAAAACAGAAAAAACTCAAATTTTCCAAAACTACAGTAACCCTAC
+AGTACTCCTACAGTACTCCTACAGTACCTCTACAGTACTCCTACAGTACC
+TGGACATCATCCCTCACCAACTTCCAATCTAATACCTCTTCAAAAGCTGA
+AAATTCAAATTTCCTATAACTACAGTAGTTCTACAGTACTCCTACACTAC
+CTCTACAGTACCACTACAGTACCCCTACAGTACCCCGACCATATCCCCCC
+ATTGACTCTAAACCAATATCCCTTCATAAGCACACTACAAAGACTACGTG
+GACTACAAACTATGTATGGTCAGACGGATAGTTTTTTTTAATATAAGAAA
+TGATGATGAACTATATATACTACTATATATACTGACACTGATTCACCAAA
+ATTAGCGACTCTGGCAATTCACCAAAGATAGGGTACGGTACTGGTATGGT
+ACTGGTACGATACTAGACCCCAGTTCTTTAATACGATTCCCTAAAATTGC
+TCACTCGGCGTTGCCTGGTCGTTGGAGTCCGCATCACAGAACACGCAAGA
+ATCCAACGGTACCGGCTGTCGTTGGACGATGTAGTGCTCGGATTTCCCGA
+TTGGGACTCCTTTCTGCAACTCTTTCAGTAATAAAACAAGTAATAAAACT
+TCGCGGGACTCCTCACCACTTTCAGCTTCGAAGCGCACTTTTTAGTTTTA
+GTCAGCACAAACATGTCGTTGAATAGAAACGCGTACATATCAACGGTCCG
+CCCGTTTTCCACAAGCTCGAGGGGGCCTTCGTGGATAAGCTTTCGACGCG
+GATGAGCCAGAAGGTTCTCGCAGAATTGACGGGATAAGGCGACGCGGAGG
+AACTGGAATTGTAAAAAATCAAGGGAAAATGTTGCAGAGAAAACAAATGT
+TTCAACTTACATCAGGGACATAAGACTTGGGCTCCAAGTCGCTTATATTC
+GGCCAGACAACCTGTGTCTGCAACTGCTGAAGCCTCTCAAAATTATGAAG
+CCACTGCACACTATCATCAATCGATCGGAGTGATTCCGTCATTGTGTCGA
+TCACCTTCTCCACCTTTCCCTTACTCTCCTCTTCCTCCGATCTTTTGTGA
+ATCTCGCGGAGAAGGATCGGAAGCCGAGTGATTCGTTGAAGCGGTGCGAT
+CAAAAGATCCTCGAGCTGTAGACGGAAGCATCGTTCATCGGCCAGACATA
+TCCGCTCGAATTCCGTGAATCGTTCCTCTTTCTGTCGAATTGAGCCGAGA
+TATTCCATGGTTGCCTTGTAGTTGATGCAGTAGGCTTGGTAGGCCGAAAT
+TGTGGAGGGGCCTTTGGAGAACTGGAAGTTTAGAGTTATAACAAGGCATA
+GTCTCAAGCTATTTTCCAGCCTATCCAAGCTGTGGTCCTGGTGCTTAACA
+GTCTTGATTTTTTAGAGCTGGAAAACCGGACTAATCCGGACTACGGAAGC
+CTGGTTTTTGTCTAAACGACAACATTGTGCAACAAGGTACGCTTTTTCAT
+ACTACTTTTTTTTAAACTTTTGTTTTTTTTTGTTCTTTTTCGGCCAGCTT
+TTAGGAACTTTTTTGACCCAACTTCGAAATGTCCCTTTTTTTTGCAATTT
+TAGGAATTTCTAGAAATTTCCCATTTTCTCTTTTTCCAGCCCCTTCTAAA
+CCTAGGCCTAGGCCTACGCATAAACCTAAGCCTACGCCTAAACCTAAGCC
+TAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTA
+AGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCTTAAGCCTGAGCCCAAG
+CCTAAGCCTAGGCCTAAGACTAAGCCTATGCCTAAGTCCCAGCCTTAACC
+CAAGCCTAGGGCTAGTTGAAAGCCTAAGCCTAACCCAAACCCTAAGCCTA
+AGCCTAAGCCTAAGTCCAAACTTAGGCCTAAGCATATGTCTAAGCCTAAG
+CCGAAAATGTCCCTTTTTTTTGCAATTTTAGGAATTTCTAGAAATTTCCC
+ATTTTCTCTTTTTCCAGCCCCTTCTAAACCTAGGCCTAGGCCTACGCATA
+AACCTAAGCCTACGCCTAAACCTAAGCCTAAGCCTAAGCCTAAGCCTAAG
+CCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCT
+TAAGCCTGAGCCCAAGCCTAAGCCTAGGCCTAAGACTAAGCCTATGCCTA
+AGTCCCAGCCTTAACCCAAGCCTAGGGCTAGTTGAAAGCCTAAGCCTAAC
+CCAAACCCTAAGCCTAAGCCTAAGCCTAAGTCTAAACTTAGGCCTAAGCA
+TATGTCTAAGCCTAAGTCTAAACCGTAGCCTAAGCCGAATCCCAAGCCTA
+AGCCTAAGCCTAAGCCGACGGAGCACGAGGAGAAAGTCCAAAACTTCACA
+AAAAAACAAACATTTCTCTCAATCTCGGTCAGTTTTCAAAAATATTTCGA
+GTAATTTTTCAGCACAAATAACAAAAACCCACCCTTTCAAACAAGTCCAC
+AACTAGCTGTGTGCAGTCCCAATTCTCCTTGTCTACCGTACTGAGCAACG
+AGAGGAACGATTGACAGAAGGTTCGAGATATTCTGACAAAATAAAAATGT
+GTGTGTGTGTGTGAAATGGCACGTCAGATTAAAGGCAAATAGAAAAAAAA
+AACCAATTAAAAACTGAACGAACCTGCAGAGTTGATCCAAATTTCCGAAA
+AGGAGGTCCGGCTCGACAAGCAGTAGACATCCCTCGACTTGACATCTCTT
+CAGCGGCTCCTTGTAAACATCGCGGAGCACGAAGAGCTGACGATAGAGGA
+AGACGAGCTCCGTGTGGAACAGCTCCCATACCGCTTGAAGGTATTTGTGT
+TTGGATGAGGGAATTGTCGTGGTCTCGTCTCCCATGAACATTTCCTCAAA
+GGATACTGGCTGAAAGTTGGATTTTTTTTTGGTATTGGAGCTCGTCTCTG
+GGCTCGTTTTGCAGTTTGTACCCTTAAAAAGACATTAAAAAGACATCAGC
+AACAAACTCCAAAATCCCAAGTAGTAAACAGATTTTTTCTAAAACGGCAA
+AATTGAGTGAGGAATTTTTATTCGATGCACCATGTTTCTCACTCAAATTT
+GACTACTCATAACTTAGTTAAACCTAATCCAATACTTCCTTAAAAGCTAA
+AAATTCACATATTCCCAAACTACAGTAAACTACAGTACCCTACCGTACCC
+CTACAGTACCCCGACAGTACCCCTACAGTACTTTGACAATATCCCCCATC
+AACTCCCTACAAAATCATCAAAAACAAAAAATTCACAATTTTCAAATCTA
+CAGTAACCCTAGAGTGATCCTACAGTATTCCTACAGTACCACTACATTAC
+CTTGACATATCCCCCACCAATTTCCAACCAAATACCTCTTCAAAAACTAA
+AATTCACATTTTCCAAAACTACAGTAACCCTACCGTATACCTGCAGTACC
+ACTACAGTACCATTAAAGTACCTTGACATTATCCCCCACCAACTTCCAAT
+TAAATACCCCTTCAAAAGCTAAAAATTCAAATTTTCCCGAACTACAGTAA
+CCCTACCGTATATCTACAGTACCCCTACAGTGCCACTACAGTACCTTGAC
+ATTATCCCCCACCAACTTCCAACCCAATACTCAATCAAAAGCTAAAAATT
+AACATTTTCCCAAACTACAGTAACCCTACCGTATTCCTACAGTACCCCTA
+TAGTTTCACCTACCAACAACTTTTCCAGCTCATCATCCTCAATCTCATGA
+TCCTTAGAAGTCTCCAACGCGGCCTGCACATGCTTAATAATCTCCCTCCG
+TTTTGCTCTGCCCGACCACTCGTAAAGTCTCTTCAGAATCCAGGGCGATC
+GATTTTTCTGCGGCTCGGAAGCTTCTGCATAGAAGGCTTGAGAGGCTATT
+GTGGCACGTTGAAGATCTGAAAATGAAGAATCGGTGGGGATCAGTGGTGA
+CAGCGAGGGAGAAGATCTATTTGGTGGGGTGGCACATATAGAAGTGGGTA
+GTAGCGGTTTTTTGTGTGATCTTTGTGTAAATAGACATGATATTAGGGCT
+TCCGTGGTAGGCAGGTGCGGTTTTAGGGCCTGGCGCTTGCCTGACGCCTG
+CCCGTCTCACGCCTGCCTGGCGCCTTTTATTCTGCATTTTGAAGTGAGTT
+TTCAAATTTCAAATTTTCTCATTTTTATCATTTTGTTGAAAATCAAATTA
+AGAAATGAAAAAAAGTTTAAGTAGGTTTCAGCATCAGGCGTGTATTTAGG
+CGAGAGGCAGGCGGGGGTCGCCTCAAAGTCAGGCAGGCAGGCCTTCTTAT
+GCCTACACGGAAGGTGTTCAAAAATCGGTTGCGTGTGTCCAGTAATGACA
+AGAATCATACAAAGCATTCGACTTTTACACAAAACTAGTCTGTATTCCAC
+CTGTACAAAAACCTACCGATCGATGTGATTTTATTTGAATCTGAAAAAAA
+AATTTCTCAGAAAATTTGAATTCCCGCCAAAATGTTTCTTTGAAAGTTTG
+AATTCCCGCCAAAAACATTCTCAGAAAATTCAAGTTCCCGCCAAAAATGT
+TTCTTTGAAAATTTGAATTCCCGCCAAAATTTTTCTTTGAAAATTTGAAC
+TCTCGCCAAAATGTTTTTTTTTTGAAAATTTGAATTCCGATAAAAAACTT
+TTTACAGAGAATTTGAATTTCCCCCTACAATTTTCACAGATCTACTTATA
+TATATATATATATATATATATATAAGTTGAACTTTAGTTTTCAAAAAAAA
+ACCGGTCATTTATTAAAGCACGTGGTGTCAAAAAATATTTTTTCGGCTTG
+ATCTACGCCGATCTACAAAAAATGCGGGAGAAAAGACGCAGAGTTCTCAG
+TTGATTTCTCATGGTTAAGAAAATTCCCGCATTTTTTTGTAGATCAAACC
+GTAATGGGACAGCCTGGCACCACGTGCTAAAGTTATAGTTAATTTACAAG
+TCCTGGTTGGACCTGCAGGATGTCAGGCGCTGAAACGTGTTTCAGGATAA
+AGTTGGTAAACTTTTATAACCAAGAGGAAAGTGTTATCGATATTTTGCTA
+GTTGAACATTTTTTTTTGCTAAAAAGTAAGAGTATTTGAGCCAGGCGTGC
+GCGGCGATCGGTAATTTCCGAAAATCGGCAATTTCGGCAATTGCCGGTTT
+TGTGAATTTTTGGCAATCGGCAATTTTGGCAATTGCCGAAATTGCCAAAA
+ATTCGATTCCGCACACTCCTGCTTTGAACTGTGCATTTCCAAAATCCAAT
+AGAAATTCTGCCGACACTGTAAAATCCCTACCTGCCAACAATCCTCCGCC
+GGAGCTGATTGCCCTATTGAACAGGTGACTCTCGTTAGGGGATATTTGAA
+CATGTGGGACAATGATCACATTGTCCGACGAGCAGCACCCTTGGGATGAG
+GTCTCCTGATTCTCACTTGGCTGATCAGGAATGATTGCATGGCGACGGGA
+AAGTTGCTCCTTGTTAGGGTGAATTGTTTGGGGCTCTCCTTCTTCTGGCT
+GGAAAAATACAATTTTTTGAAGTTTTTGAAAGAAAGCTTGTCATTTTTTT
+GTTGCTATTTTTTACCCTAAAAATGTGGTTTCAAAATTTTTTTACCTCTG
+AATATCTAATCAACGGGGTGAACAACTGCAGATCGACCATACTCGAGCTT
+CTAAAAGTTTGAAGGAAGCTTCTCGTGAAGCACGAAAAAAAAAGAAACAC
+GAAATAGTTACCCTTACAATTATCAGAATAGGATGGGATGTACAGAGAAG
+TAAATAGGAAGAGAAATGAGAAGAGTTGCACTAGAGAAGTATGTACAATT
+AATAATTTATGAGCATCTGAGAAAATGAGAGCGACTTGAAAATCTGAAGA
+GCAAGGAAGATAAAACTCGGTCTCTTATCAGAAAATTTGAATTCCCGCCA
+AAATGTTTATTGTTTAATTTGAACTCCCGCCAAAACTTTTCACAACGAAT
+TTGAATTTTTCGCCAAAATTTTTCTCAGAGATTTTGAATTTTCCCGCCAA
+AAGTTTTACCAGAAAATTAAAATTCCCGCCAAAACTTTTCACATCGAATT
+TGAATAACCCGGCAATTTTTTTATCAGAAAGTTTGAAATCCCGCCAAAAT
+TTTTCACATGAAATTTGAATCTTTCGCCAAAGATTAAAATCGTTGGATAA
+TTTTAATTCGCGGCTGAACGTTTCCAATTCGAATTAAGACCGGCCAAAGT
+TTTTCGGGGTTTTTTTTAAAACTTACTACAAAAAAGCATACATTTATTTT
+CCTAACTAGACGCCTTACTAGGTAAAACCCGCTTTTCACATCAAAAACTT
+CAACAATGCGTCACCGCCAAAAGAGATTCTTGCACTTCACCACGAATAAT
+AGATCAGAAGGAAAAGCGTGTAGTGAGTTGAGAATTATAACTAATTCATA
+TCCCCCGAAAAAAAAAACGCTGATGTCTATATTCTATACATGGTGAGAGC
+TCACCGAAGAATAGACGGGTAATGAGATATATATGTGATACATAAATGTG
+TGCGCCCGGGTATCCGAGAGCCGAAAACAGAAGCATGGAATGGAGCAACT
+AGGGAAAATTGTGTTATCACGAGGCACGGCGGGAGACACAATAATATGAT
+TTTTTTTCGAAAATTTTCCATTTTCACGTGGTTGTCCCATTACGATTTGA
+TCTACCAAAAACGCGGGAATTTTTCGCCTAAAAAAATGTAACGTCAGCAC
+GTTGTTTACCATGAGAAATCAGTTGAGAAATTAGCGTCTCTTCTCCCGCA
+TTTTTTGTAGATCTAACTTGATCAAGCCGAAATGAGACGCTCTGACACCA
+CGTGACGAAAAAAAGTAGATCAAAATTTGGCAAGCCCTTATAAAAGTCCC
+TTTTTCAGTTCTAGGCGGAGCTCAGTTTGACTGATGACGTAAACGCAAAT
+CTTGAAATTTCGAATTCTCTATGGAAATTAGAACTTCCCGCCGCCGCCAG
+ACTTTGTAAAGTTCAACAAAAAGATGAAATATAGAAAAAGTTCAGACTAT
+GATAAGGAACTTATGACTAACGTCTCTTGAGGTGAATGAGTATGATGTGA
+TTAGTGATGCAAGACGACTAGACCGAGAGAGAGAGAGAGAGAGGCTCAGA
+GAGGGGGGAGGGAAGGTAGGTTTGTAGGTAGGCAAGCAGGTAGGCAAATA
+GGGGGTCGTAAGTAGAAATTATGAAGGAACCTAGGTCGGCAGCCATAAGG
+TAGGCATAAAGTAGGTCAGCATCCAAGTAAGTTAGACAGGTACGCATAAG
+ATAGGAAGGTAAGTAGGCGCGGTGGCAAGGAGACTCAAGGCAAAGTAGGA
+CAGGAAGTAGGCAGTAGGTAGGCACGATGAAGGTAGGTGGGTAAGCTTGT
+AAGAAGGCAGCCATAAAGTATGAACGTCGACAGTAGGCATGCATTTAGTA
+GGTAGGTATGAAATAAGAATTAAGGTATGCATAAGGAAGTAAAGTATGAA
+TGATGAAGCCATGTAGATACAGAAATATCAGGCAAGTAGACAGGCAGGCA
+TAATATAGGAAAGTTAGCAGTAGGTAAGCATGTAGTAGGTACGTGGGTAG
+GCATGTAGGTAGGCACGTGGTAGGCTTATGGTAAGCAGAACACAAGCACA
+GAAATATGCATATTGGCAAGTATGTAGGCATGCATAAGATACAAAAGTCG
+ACCAGGCATGTAAGTAGGCACATAGGTAGGCAGGCTTGAGGCAGCAATGT
+AGGTGATCTCGTAAGTAGGTATGAGTAAGGAACCTAGGTAAGTCACAGGT
+ATTTGGCACAACCTGTGTTCTTCTCAATGGTAATCAGGCGAACGTGCCTG
+CCTGCCTACCTAGAAATTCGGTAAAAATTGTGGAAAAAAAACTAGGGGAA
+CCTCTTCCCAATGGAATGCGTAATGTGAGTGGGAGGCGGCAAAAAAAGAG
+CGGACGTAAACACTTTTTCCTAATTCTCTTTTTCTCTCGCTCGTGGAAAA
+TGAATGAATATTTGATACAATTTTGTGGGTACAGCCAGCAGGAGAAGAAG
+AAGCTGATGTCCCGACGCGCGCGCGCGAAAAAAACTTTCAATTCCCTCCC
+CTAATTATCCGCCTAACGCCTAATGTGTGTCAAATTTACCATGTATTTTT
+TTCTCCTCTCGGCTATGTTTTTTTTTCTTTTTCAGCAAAAAAAAGTACGG
+GCACATGAGGTCGGGATGGATAATTAGGGATGTGTGCCAATTTGTTGGAT
+AATAGACAAAAAAAGTACGTGAGATTTTTAGAAAATGCTGAGAAAAATAT
+CACGAGGCGTTGGGGACGTGGCCGCGAATGAGAAAACTAGGCCACCTTCA
+CAGGGCCCTGGCCTTCCTCATTGAACTTTTCGCGCTCTACTGACAAACGC
+CCGTGTACTCCACACGGACAAATGCATTTAGTTTTGCAGCTAGAATCGAT
+CAGCGACGCGACACGCAACGCGCCGTAAATCTACCCCAGATATGGCCGAG
+CCAAAATGGCCTTGTTCGGCAAACTCTTCCATTTCAAATTTTTTATTCAG
+TTTAATTTTCTAGGATACGCCTACGAGTGATCTAGGCCAGGCAGTAGGTA
+GGCAGCCAGTGTAGGTAGCCCCCTTTTGGTGTCAGGCTGTCCCATCGCGG
+TTTGATCTATCAAAAATATGGGAACTTTTCTCCCAGTAAAATGTGACGTC
+AGCACGTTCTTAATCAGGCGAAATCAGTTGAAAAGTCTGCGTCTCCTCTC
+CCGCATTTTTTGTAGATCAACGTAGATAAATACGAAATCAGACACTCACG
+TGGTGCCAGGCTGTCCCATCGCGGTTTGATCTACAAAAAATGCGGGAACT
+TGTGCCCAAAATTATGAGACGTCAGCACGTTCTTAATCAGGCGAAATCAG
+TTGAAAAGTCTGCGTCTCTTCTCCCGCATTTTTTGTAGATCAAAGTAGAT
+CAATCCACATTAAGACCTTCTGACACCATGCCCGAGAAGAGTTCAAAATA
+AATTTCGTAGAACATAAATTTTTCCACGTGGATTTTACAGCACAATTGCT
+TATAGAGCGCGGTTGCACCCCAAATTTTACAGGAAAAATAGGAAAATTTT
+ACCAGATTTCCCGCGCAAGACACGAAACAAGGTCTTAAAAAGTGGGAGAG
+CATGAAAAATCCTAAGAAAGTAAGAAACTTCTGGTTTACCACATAACTCA
+AATTGGAGATAGTTCGACCTTAAAAATTTTGCACCAAAAAGGGCGGAGCC
+AAAAACACCAAAACTTACGTGCAAATTTGTACATGAAAAAACTAAAAAGG
+ACACCTAAAACCGGCGAAATATGAAGAAAAACGCTGAAAATGAGCAATGT
+GTATCAATTTTTCCCCCGTTGCTTAATTTAATACATGTCTTCCTCTCCCC
+CTTCCTTCCTGCTTCACACTCTTTCGGGCGGCGCCTCCTTTTGATTTGAG
+ACTTGAGACTTTTTTTTTTGTGATGTGCGTTGAGTAGTGTGGGATGCATA
+TATTATGAATCAAAAATCTGACATCAAAAATATCGCTGAAAAAATAGTTA
+AAATTTGCTTTAAAACTGCCGTTTTTGATCTACAGGGTGCTTTGGCGCGT
+TGCGGTCGCGTCGCGGCTTGGAGTTCTAGGCCACGGCCATTCAATTTGAC
+ACTACTACAATCAGAAATATTTTGTAATTCTTAGGCCATCAAAAAATTTT
+TAAGCCAGAAAACAAATCCGGAAATTTCTAGGCCATCAAGAATTTCTAGG
+CCACATCAGACTACTTTGAAAATTTCTAGGCCACAATGGGAACTAATTTC
+TGAACCTAATTTCTGAAATTTCTTGGCCACGATCTGAAATTTCGAAGCCA
+TAATTTGAAATTTCTAGGCCACGATCTGAAATTTCTAGACCATCAACAAT
+TTCTAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAAATTTGTAGGT
+CAAGGTTTGAAATTTCTAAGCCACGATTTGAAATTTCTAGGCCACGATCT
+GAAATTTTTAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAAATTTT
+TAGGCCACGATCTGAAGTTTTTAGGTCATCAAAAATTTCTAGGCCACGAT
+TTGAAATTTCTAGGCCACGATCTGAAATTTCTAGGCCACGATTTGAAATT
+TCTAGGCCACGATTTGAAATTTTTAGGCCACGATCTGAAATTTCTAGGCC
+ATCAAAAATTTATAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAAA
+TTTCTGGGCCACGATCTGAAATTTCTAGGTCATCAAAAATTTCTAGGCCA
+CGATTTGAAATTTCTAGGCCACGATTTGAAATTTCTAGGCCGCGATCTGA
+AATTTCTAAGCCATCAAAAATTTCTAGGCCACGATTTGAAATTTCTAGGC
+CGCGATCTGAAATTTCTAAGCCATCAAAAATTTCTAGGCCACGTTTTAAA
+ATTTTTAAAATGTTTAAAATTATAGGTTTTCAAAAAAATTCTAGGCCATC
+AAAAATTTCTAGGCCACGATTTGAAATTTCTAGGCCACGATCTGAAATTT
+CTAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAAATTTTTAGACCA
+CGATCTGAAATTTCTAGGCCATCAAAAATTTATAGGCCACGATTTGAAAT
+TTCTAGGCCACGATTTGAAATTTCTGGGCCACGATCTGAAATTTCTAGGT
+CATCAAAAATTTCTAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAA
+ATTTCTAGGCCGCGATCTGAAATTTCTAAGCCATCAAAAATTTCTAGGCC
+ACGTTTTAAAATTTTTAAAATGTTTAAAATTATAGGTTTTCAAAAAAATT
+CTAGGCCATCAAAAATTTCTAGGCCACGATTTGAAATTTCTAGGCCACGA
+TCTGAACTTTCTAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAAAT
+TTTTAGGCCACGATCTGAAATTTCTAGGCCATCAAAAATTTATAGGCCAC
+GATTTGAAATTTCTAGGCCACGATTTGAAATTTTTAGGCCACGATCTGAA
+ATTTCTAGGTCATCAAAAATTTATAGGCCACGATTTGAAATTTCTAGGCC
+ACGATTTGAAATTTCTAGGCCACGATTTGAAATTTCTGGGCCACGATCTG
+AAATTTCTAGGTCATCAAAAATTTCTAGGCCACGATTTGAAATTTCTAGG
+CCGCGATTTGAAATTTCTAGGCCGCGATCTGAAATTTCTAAGCCATCAAA
+AATTTCTAGGCCACGTTTTAAAATTTTTAAAATGTTCAAAATTATAGGTT
+TTCAAAAAAATTCTAGGCCATCAAAAATTTCTAGGCCACGATTTGAAATT
+TCTAGGCCACGATTTGAAATTTTTAGGCCACGATCTGAAATTTCTAGGCC
+ATCAAAAATTTATAGGCCACGATTTGAAATTTCTAGGCCACGATTTGAAA
+TTTCTGGGCCACGATCTGAAATTTATAGGTCATCAAAAATTTCTAGGCCA
+CGATTTGAAATTTCTAGGCCACGATTTGAAATTTCTAGGCCGCGATCTGA
+AATTTCTAAGCCATCAAAAATTTCTAGGCCACGATTTGAAATTTCTAGGC
+CACGATTTGAAATTTCTAGGTCACGATTTGAAATTTCTAGGCCACGATTT
+GAAATTTATAGGCCGTGATCTGAAAGTTCTAGGTCATCAAAAATTTCTAG
+GCCACGATTTAAAATTTCTAGTCCATCAATAATTTCTAGGCCACCAGAAA
+ATTTGTGTTCACTTTTTTTTTTGGTTTTTGGTATGTATTTTTCAGAAATT
+ATTCAAAATTTGTGGGAGCAACAATATGCTTTTTTAGTTTCTAGGCCACA
+AAATTCTTTGGCCATTTTCACATTTTTTCCCGCCGCCAATGGTTCCACTG
+GATAATTGAATGTATAGAAAAAAGGGAAGAGTTCAGCTGGCGCAAAAGAG
+GGTAATTCGTTGGAAGGGAAAAAAATAAATGCAAATCTTCGCCAAAAACC
+AATTTTCGGTCGGAGCTCGGCGCGGGCCGACACACACAAAAATGGAGCAG
+AAGAAGACGTCAGAATCTTCTTTTTCAGAAGGCTTTCTCACTTTGAAAAT
+GGGGTGTCCAATTTCTTGTTGCTAATTGTTGGATGGGGAAAGAATGATAT
+TTTGTTTCAGGTTTCACACAACATCAGCCTAGACATTTTTTTTTTGTTTT
+CTCCAAGAGGAGTACACACACTATAAATTGTTGTAAAAATCGAAAAACAC
+GTGGAGCCAGAATTTCTTATTTCGATTTGATCTACAAAAAATGCGGGAGT
+TAAAACGCAGACATCTCACCTGATTTCGCAAGAGCGTGCTGACGTCACAA
+TTTTTTTGGAAAAATATTTCCGCATTTTTTGTAGATCAAACTGCAATAAG
+ACAGCCTGGCACCACGTGAAAAATAGTATTCCTCTTGAAAAAGATTTCCC
+GAATCAAGTTCCTTGAAAGGAGTACGCAAAATTTTGCAAAAAAAATCGGT
+GGCCGAGTTTACTCTTCTGGCGGCCACGTAACAAAATTAACAAGGAAGGA
+TAAAAAGGAAAAAAAAATTTTACTCGTAAAAAGGTACCAGGAAGCAATTT
+GAGGAAGGAAGGAAATGTGAGTGTCTACTCTAATGATCTACCAGTTTTGG
+TGGCCGCGGAACAGAGAAAGCTCGGCCCCCAAGTATTTTTTCAAATATCA
+CGGATTTCTGGTTTCCCTTATAAGTTGAAATGGAAGAGTTTTTAAAGAAC
+GAACTAGGCCATTTTAGCTCGGCTGGGGCAGATTCACGGCGCGTTGCGTG
+TCGCGTCGCGGCTCGATTTTAGTTGTAAAACTAAATATATTTGTCCGTGT
+GGAGTACACGACTTTCCCACGAGTTTTCCGACAGGCGATTGTCAATGGAG
+CGCGAAAAATTCAATGAGGAAGGCCAGAAACCCGTGAGATATTTAAAAAA
+TATTCCAAAACTATTTTTATATTCAAAATTGGAAATTATACATACTATAA
+GTATTTTCAACTACATACATGGCCGCGAAAAAAAAAAACTCGGCCACCAA
+TTTTCGCGGTCACTTACCGCAGATCTCCATCGATCCTGAAGTCTTGCCGT
+ATACAATAAGGGCATTTTTCGGATCATAGTGAATGAATTATTTCAGGAAT
+ATTATTTCAAAGAACACACACCACACAAGAAATGTGAAGGGAAGGAAACG
+GGGAAAAAGAGACAGGTGGAAAAATACATTTTCTCTATTATTTCGCTCTG
+TTTCTGACTAGGAAATGAATCAGAATCAGTGATTAAGAAACTGGGAATTT
+ACGAGGTGTTTAGGGAGATGGTGACCGCGAGGATGAGGAAAAACTCGGCC
+ACCGCAAGACTTACCGGCTTAATCAATTGATTTCCTCGTATGTGATGGAA
+CAATGTGAGAGCCGGAGCTTCACTCGTCATAGCTTTGTGTCTAGGTGGCT
+CTCAAGTACTGCTGGACCTGAAAAACTGCAAATTTAATTTGAAATTTGGG
+ATGCAAAAAAGTAGCAGCCGACACCTGCCGGGTTCCCGCAAGATGTCGGA
+TGCTTCAATTGACCTAGTAGAATCGTTAGTGATCTACCGAGCAAAAACAA
+GTATGCTTGCAAGAAAAAAAGGCGTGTGGCTCAAGTTGACAAATTCGACA
+CTTTGGACACACGAAATTGGATGAGCCACACCACACCGGCTAGCTCAGAA
+GAGCCCCTCCGACGTCAAGGACCCCATGTGCGCGCGCGAGCCGAGATTCT
+GGCAACATGAGAAGCGGAGAAGGCGAAGAGAAGAGTGCTAATTTGAACTT
+GTTGCTGCAGGAAAAATATCTAGGCTTAGGCTTAAGCTTGGGCTTAGGCT
+TAGACTTATGCTCAGGCTTAGGCTTAGGATCAGGCTTAGGCTCAGGCTTA
+GGCTCAGGCTTAGGCTCAGGCTTAGGCTCAGGCTTAGGCTCAGGCTTAGA
+ATTGGGCTTCGGCTTCGGCTTTGGCTTGGCTTAAGCTTAGGCTTAGGCTC
+AGGCTTAGAATTGGGCTTAGGCTCAGGCTTAGAATTGGGCTTAGGCTCAG
+GCTTAGAATTGGGCTTAGGCTTTGGCGTAGGCTCAGGCTTAAGCTCAGCC
+TTAGGCTTTGGCGTAGGCTTAGGCGTAGGCTTAGATTTAGGTTTAGGCTT
+AGGCCTTGGCCTAGGCACAGGCCAAGGTTTCAGGTCACTATCACTTGCTC
+CTAGGTGTGGCTGGGGAAATGAAATTCTAGGCCAGTGACGTCAAGATTCT
+GGAAGAGTTCCGTTGACGCCACCAAAAGCAACAAAAACTTCAAATCTGAG
+AAGATCAGAACAAAATGTACTGAAAGTACAAAAAGCCCGCACTTTTTTCT
+CTATTAATACTACTCATTTGAAGAGTGGGGAAAAGAAAAATGTGTTGCAA
+GAAATAATTCCGTGCGAAAAAAGTTTGAGAGGAATGAATGGAGCGGAACT
+TTTTTTTTTGTTGGAAAATCGTAGGTGTGACGTCACTTCTCTTCCAACCC
+CCAGGTTTCTAGGCCACTTAAGAATTTTGCAAAAAAATCACAGAGCAAAA
+CTACAAAAAGGAAAGAAGAAATGTGCTCTTGGAAAATAATAAATATTGGT
+TACGAAATAAAAGAGAAAAGAGAACGAAAAAAATAAAAAAGAAAATGGTA
+ACCAAGGAGGAATGTGGAGAAGAGGCTCTTGTGAGCCCAGATATACCCAG
+CAATTAGGGAGCGAGTACTACTGCCGGGAGATGACGTTTCGAGGATATTT
+CTCACTGGAATGGAGGGTGGTGGAAGAGTTTTGTAAAGTTCTAGGCCACG
+GGTTTTTTTGGCCAATGAGCATGGTGCATCGATGAAAAGCTATTGGGTTT
+CTCGGCCACAATAAATTACAAAAACCTAGTACGATGGAGCACACTTGCAA
+TAGAATTGCAAAAATTTATTTGAAAATTGAGAAGAAAGAAAATCAGGGGG
+GCATAAATGCTCAACAGTGCAATCAAATTGTAGAAGAGCTTTCGCCCAAA
+AAGCTAGGCCACGGAGGAGACCGCTGGAGAAAGTGACGTGTATATGGTGG
+AAGAGTTTTCTTGTTTTTCTAGGCAATCTTGGGCGATTGCAAAAATTGAA
+TTTATGAAAAGATGGCTTGGAAGAGCTTTCGCATAGAAAATCTAGGCCAC
+GGCTAGCAATTTAATAGGGGATAGAAAACCGCGTCGGAAGATTATTTAAC
+TTTTCCATAAAAATTAGCAAATTTAAGAGAGTTCAGATACTGATCTGGAA
+GAGTTTTTGAGCAAAAAACCTTGGTCACGGCCAGCAACTAAAGTAGTAGG
+GGAGATAGGGTACCCCGCTAATTTTTTATTTATTTTTCAAAGAAAGTTTT
+AAGGTTTCGGGAAAAATTTTGATGAAATGGCTTGGAAGAGCTTTTGCCGA
+AAAAACTTAGGCCACGGCCAGCAATCTAATGAGAGGGGGAGGGTTCCCCG
+CTAAATTTTTTTTTTGATTTTTAAACAAAGTTTCATGGGTTCGGGGGAAA
+ATTTGATTAATTGACTTGGAAGAGTTTTTAAGCAAAAAAAAACCTAGGCC
+ACGGCCAGCACCCTAATGAGAGGGGGGAACATAAGGTACCCCGCTATTTT
+TTTTTGATTTTTCAAAGAAAGTTTTAAGGTTTTGGAGGAAATTTGATTAC
+ATGACTTGGAAGAGCTTTTGCAGAAAAAAACTTAGGCCACGGCCAGCAAC
+CTAAAGTAGTATGGGAGATAGGGTACCCCGCGGAAAATTTTTAAATTTTG
+GTAAACAACAATGGAAGAATTTTCCGGTTTTCTAAGCCATTGCATTTTTT
+CAGCGTCACGGATTTCTGGCTTCCCTCATAAATTGAAATGGAAGAATTTG
+CCGAACTAGGCCATATCTGGGGTAGATTTACGGTGCGTTGCGTGTCGCGT
+CGCGGCTCGATTTTAGTTGCAAAACTAAATGTATTTGTCCGTGTGGAGTA
+CACGACTTTCCCAGGAAGGTGATTGTCAATGAAGCGCAAAAAATTCTCAA
+AAAAAATCCAGATTCCCGTGCAGCGTCGCAGGAGATCATTTTCAAGAAAT
+CTGGCTCAAGAAGGATTCAGTAAAACAAGAAAAGAAATAAAAAAGGAATG
+AAAGGTAAGGGTGGACAAGTCGGCGGGACAACTTGTCACTTGCCATCATC
+ATCATTTTTCTTCTCCTCCTCATCAGCTTCTGCTGCTCCGCGAGCTCGCG
+ATGACTCTTCTGAAATTCTAAACTTGGCCAACACAACGTCGGCAACGAGT
+TTCGAATTTACACACACACACACATACGAAAAAAGCTCATTAATTGGAGC
+AGGAGACGGAAGAGAGGGAGGAGAGGCTGCTCAATGAGTTAGAGAAGAGA
+GAGAGAGAGAGAGACTGAAAGATGAAGTATAAGCAGAAGTCGTCGGGATG
+ACAGAAGAAGGAGGAGAAGAAAACGTGAGAAGGGGGGATGTGGAGACAGA
+AGGATATGTAAATATATTAGATTCAAGGATTACAGCAATTTTAAGGAGGC
+AAAAAAAAACAACGATGCTCCGATATTTTTGGGGTTACTGTAGTTTTTGT
+AGATACTTCCAGAAGTTATAAACAAATCCGAGTTTTTTAAAATTTGCCAG
+AAGCACGGGTTCATTGAATTTTTCACGCTCCATTGACAATCGCCTGCCGG
+ACAACGCGTGGGAAAGTCGTGTACTCCGCACGGACAAATACATTTAGTTT
+TACAACTAAAATCGAGCCGCGACGCGACACGCAACGCGTCGTAAATCTAC
+ATATATGGCCGAGCCAAAATGGCCTAGTTCGGCAAAAACTCTTCCATTTC
+AATTTATGATGGAAGCCAGAAATCCGTGCAGAAGTTTCTCGGAAAAAAAA
+CAGAAAGTTTGCGAAATGGCAACCTCTAATTCATTAACATAAATACATCA
+AATATGACGCGCAAAAATGAATTAATTTACTAGTGAAACATGGTGCATTG
+AAGTCGGTGTTTGCACAATTTGTACAGATCTGAGGTTCACTAACACCAAT
+GCACGGCCCGAGAAGTGGTACCTGTACGCAATTTGTCTACCGTATACCTG
+GACGTTTGGGCGCGTGTATCTCAAAAACGGTTGGTCCAGTTTTTTTGTGA
+TGCATATAAAAAATGTCCGAAATTAAATTCTAAATTTTTTGGACCAAAGC
+TTTTTTCGTTATCACGCGCCCAAACCTGGTCTACACTCAAATTATCAGTA
+GAGCGCATTTGCATGGATGTACCACTTGCCGGGCCGTGTTCAAAGGGGTG
+CAACGATTGCGCGTCAAATCGAATGCAACTACAGTAATCCCTAGTAGTTG
+CGCTTCAAATTTGATGCATTGCACGGCCCGGCAAGTGGTACATCCATGCA
+AATGCGCTCTACTGATAATTTGAGTGTAGACCAGGTTTGGGCGCGTGATA
+ACGAAAAAAGCTTTGGTCCAAAAAATTTAGAATTTAATTTCGGACATTTT
+TTATATGCATCACAAAAAAACTGGACCAACCGTTTTTGAGATACACGCGC
+CCAAACGTCCAGGTATACGGTAGACAAATTGCGTACAGGTACCACTTCTC
+GGGCCGTGTTGAATGTTTGAGAAATGTTAAAATTTTGAGTTATATGTGCT
+GGAAAATTGACATGAACATGGTTTTTTTCATTATTTGCGCGTGAATTATG
+GTGCATTGAAGTCGGTGTTTGCACAATTTTTTTCAGATCTGAGGTCAACT
+GACACCAAAGCAACAGAGTTGACGCGCAAATTTTAAAATGCGCTTAACAT
+TTGGCACGCTTTGCAGTCGGTGTTTGCACATTTTCGATTGTTGTGTGAGG
+TTCACCGACACACCAGATTTGACGCGCAAAATTGTACGAAAACAGTTAGT
+TAGAAAACTAATAAAAACTATTAATAAAAGTATAGTGCATCCTGAAAAAT
+TATTTCTGCAAATGTATCTATAGAATTTAAAACAAAATATACAAAAAAAA
+ATTATGAAAACCACGACGAAAAACCCGGAAATGTTTTTTGGGTAGCTTGT
+CGATTCCGGAGGGTATTGAATTTCGCGCTCGAATAATATTGTTTCCTATT
+CATTTTCCCCAGAATACCTACAGAATTTGGGGGAAAAATATGAACTGGTA
+CCTAACATTAACCTACACGTTTTTTAAATAAGTTTAGGCCACGCCCAGAA
+AGTAGCTGGGCGGGGTTGCAGATTTTTCTAGCTTTCCGAAATATAAAAAG
+TCGGAAAAAAAGTTGTAGTCTGTAGTTTGTAGTTTGTAGTTTGTATCAGG
+TTGTCCCATAAGTTTTTGTACTTTTTTTCAAATATTTTTCCAAAACTTCT
+AGAAAGTTTTAAAATTTTTTCATCGTAGGTCGTGTCAAGGTCGGGTCGTC
+CCCTTTCAGAAAAGATTCATTTCATCCATTTCTACTTTGCCACGATGACA
+ATCATCAAACTTGAACGTCGAGACGTTAGATTGCTTCTTCTTTATGAATT
+TCGTCTTGGTCATTCAGCAATGGAAGCGGAACGAAACATATGCGGTGCGA
+TGGGTGAGGGAGCACTCTCTTATAATACAGCAAAGAGTTGGTTTCAAAAG
+TTCAAGAACGGCGACTTCAGTCTCGAAGAAATAGAACGTTCTGGGCGACC
+GGTAGAGTTAAATGAAGAAGACCTAGTGAAGCTGGTGGAGGAAGAGCCTC
+GTCTTAGTCTTCGTGAAATGGAAGAGAAGCTTGAGTGTTGTCATAGCACA
+ATTGCACGTCACTTGGGTCGCCTTGGTTTTACTTCAAAACTTGGAACTTG
+GGTGCCTCATGAACTTTCGGCATCACAGAAGCTCACTCGGGTCAACGTTT
+GTACTCAACTTCTAACTTTTCGTCGAAAGTTCGATTGGCTGAACAATCTG
+GTTACTGGAGATGAGAAGTGGGTGCTCTATGTTAACCATTCCAGAAAACG
+TCAATGGCTTCCGATCGGTGAGAAAGGAATACCGACGCCAAAGCCTGATC
+TTCACCCAAAAAAGATTATGATCTGTGTCTGGTGGGGTGTTCAAGGACCC
+GTGCACTGGGAATTGTTGCCAACTAATAAAACTATCACTGCTGATTACTA
+TTGTGCCCAATTGGACCGAGTTGCAGAAAAGACCAACGGAAAATATGAAA
+AACTATATTTTCTTCACGATAATGCTAGGCCTCATGTCGCCAAGAAGACT
+TTCCAAAAGCTGCAAGATCTTGGTTGGACTGTTTTACCGCATCCACCATA
+TTCTCCAGATCTTGCACCAACCGACTACCATTTGTTCTTGTCTCTCAGTG
+ACTACATGCGCGACAAGCAATTCGACGACGAAGAGCATCTCAAAACTGAA
+CTCTCCACTTTCTTCTCATCGCGTTCGCCGGATTTCTTCTCCCGTGGCAT
+CATGATGTTACCTAGTAAATGGCAACAAGTGGTGGACACTAATGGTGAAT
+ACTTGTGTGAATAGTACTACTTGTCGCTTGAGAGAAATAAATTTTTTTCA
+AAAAAAAAATAGTACAAAAACTTATGGGACAACCTGATAGTTTTAGTTCG
+TTATTTGCAAATTGTTAACGTTAGTATTAGGAGAGCCGAAATAAATAAAT
+TTTAGAAAAGAAAACGAAATTATATACATAGTTCATTAAAATGTGGTAGT
+TTGTAGTTTGTAGTCTATGTATTATGTCTATTCAAATTGTATTCAACATC
+AAAAATTAAACAGGAAACTTATATTTAAAAAAAAAACGAATACTGAAAAA
+AGGCGGCTGCATAGGAAAAAACAATGATTCTCCTCCAAAAAATAGAATTC
+CGCATTTTTTCAGCGGCTATTTTCACGATGATGAGAGGAGACAACAAAAA
+CATTTGAGATGAGAAATGAGGGGAATATTGCACAAAAATTGGGAAATGAT
+TTTTTTTACTTTATACACAGTTAAAATGCGATGCGCGCATAGTGTTTTTG
+GCGTGGATCGCGAGTGGGAGAAAAAGGAACCGGAAATGATGCGCATTGTG
+CGTCCATCGCGAATTTGAGATGCATTGTGCGAGCATCGCGAACATAAATA
+ATGGGCACATTGTGGATTCTCCTTTCTGATAATATTTTACTCTCTATGGC
+TTCACCAATTATCTTTCTCTCTGTGGCTTCCCACTATATTTTACTCTCTG
+TGGCTTCACCAATTATTTTACTCTCTGTGGCTTCCCACTATATTTTACTC
+TCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCACCAATTATTTT
+ACTCTCTGTGGCTTCCCACTATATTTTACTCTCTATGGCTTCCCACTATA
+TTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCAC
+TATATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTC
+ACCAACTATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGG
+CTTCCCACTATATTTTACTCTCTGTGGCTTCACCAACTATTTTACTCTCT
+GTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACTATATTTTACT
+CTCTGTGGCTTCACCAACTATTTTACTCTCTGTGGCTTCCCACTATATTT
+TACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACTAT
+ATTTTACTCTCTGTGGCTTCACCAACTATTTTACTCTCTGTGGCTTCCCA
+CTATATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTT
+CACCAACTATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTG
+GCTTCACCAACTATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTC
+TGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCACCAACTATTTTAC
+TCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACTATATT
+TTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCACCAAC
+TATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCC
+ACTATATTTTACTCTCTGTGGCTTCACCAACTATTTTACTCTCTGTGGCT
+TCCCACTATATTTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGT
+GGCTTCCCACTATATTTTACTCTCTGTGGCTTCACCAACTATTTTACTCT
+CTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACTATATTTTA
+CTCTCTGTGGCTTCACCAACTATTTTACTCTCTGTGGCTTCCCACTATAT
+TTTACTCTCTGTGGCTTCCCACTATATTTTACTCTCTGTGGCTTCCCACT
+ATATTTTGCTCTCTGTGGCTTCCCTCTATATTTTACTCTCTGGCTTCACA
+GTATATTTTATTCTCTGGCATCACAATATATTTTACTCTTTGGCTTCGCA
+GAATATTTTACACTCTGGCTTCACAGAATATTTTACTCTCTGGCTTCGCA
+GAATATTTTACTCTCTGGCTTCGCAGAATATTTTACTTTTTGGCTTCACA
+GAATATTTTACTATCTATTAATCTATTTCTTCGTATAACAATCTATTTTT
+TCGTATAACAATCTATTTTTTGTATAACCAACTTCAAACTCAACTTTTCC
+AAAACTACAGTAACCCTACAGTAATTCTACAGTACTCCTAAAACTCCCCG
+CAACCTGCAGTTCAATGACACCTCGTTTTCTCACGCGTGACTCATGACTC
+ATTAGCTTACATTTCCTTCATCCATCGGTGGTGGGGCGCTGTGTAATATA
+CAAGAAGAGACACCACCACACGCTGCTATTTCTGCTGCTGGTCTGTCTTC
+GTTTACAGCCACTTATGACTCAGCACTGCCATCAATGACTACTTCCTTCT
+TTTTTATCTTTTCGGCTTCATCTCGAGTAGCAAATTTAACAAAATTCAAT
+AGGTGTGACGTCATCAAATGCCTTCGTGGCCTAGAAATCCAAGATTTCTC
+TCGAAAGGATCAATGTGATGTCATGGCCTAGAAAACTCCAGTGTGAAACC
+TAGGCTATGTTAAATAGTCTTGAAAACTCTAAACTGAAGCACATAAGGCT
+ATGATGTCATCGCCTAGAAATCCCAATTCTATGACGTCATGAAAGACCTG
+AACTGCACCGAACCTAGGAATACCCTCAAAAGGGGTGCTGTGAAGTCATG
+TCCTAGAAAACATGAGTGCGAAAACTAGGCCGTAATCTACCATGTGGTAG
+ATCATGCGGCCCTATTGATGGCCTAGAAAACTTACAGCTTGAAGCTATGA
+CGTCACGACCTAGAAACTCAATAGTTGTGACGTCATCAATGACCTAGGTG
+TATCTCGAATGACGCAGTGTCTTCTAGAATTTTCTGAATATCACACAAAA
+GTATAACATCTTCTTGAAACCAAATAATTTTGTTGTAACACCCACACAGT
+ATTGTAACAAATGATATAATAGCGATCGGAACATTCGAGAAAACTGGAAA
+TTTGAGGTCTGACCTTGTTCGGGAAACTTACCAGTGATTATGAGGTGTGT
+CGAAAAATGTGGCCTAGAAAATGGGAAAACTCTTCCTTTTTTTTTTTAAG
+TCCAGAATTACGTTTTTGAGAACGAGAAGTGCATTTCATTTTTGTTAGGT
+TGGAAATTTAAAATTTAAATATTCGTCTCCTAGTTACAGCCGTGGAAGAC
+TTTTTCAGAAACTTTAGCCACGTGTCGAAGTCTGGCGGTGCCCACGATAT
+TAGAGAATGTTGATATTTCCTATTTACTTATCTCCTCGAAATTTTAAGAT
+TAAAGTTACTACCGTTAAGTTACACTGGTGGAAGAGTTTTTAAGATTTCT
+AGGCCACGGCAAAGTTTGGGTGTGCCAGTGACCCTAACACTAAATTTTTA
+AATTTTTTTCAGCCAAATCATCATATGGTGGCCTAGAAAATTTAACACCT
+GAAAACTCTTCCATATTTTTTTAATTTCTGAAATCCAACAAAATAATTTT
+CAAACTCCTCTTCCTTTTTTCCAGAAAAATAAATTAATGTAAATCAAGTT
+CATCTCCGATGAGTTGTAACGGTGGAAGAGTTTTTCAGATTCCTAGGCCA
+CGTCAAAGTTTGAGGGCTTCCCGTGACCCTAACACTAAATTTTCCAATTT
+TTTCAGCCAACCCAAATCAGAAGCTTTCTCTTTGTGTAATAACATGACAA
+TGGGCTATTATCATATGAAATTTTTTAGGTTAAATTTCTGAGGTCATTTG
+CAAAGGTGTCATGACTAGTTTGGAGGCTTTTTTGTGACGGTAGGGGTATG
+AAACAGGTTGTTACTTCTCGAAAAGGTATTATGTGGGGGAGAGGAGAAGG
+AAAGAAGGAAGGCAGATTAGCCAACAGAGATACAGCAAATTTTGTGTGAG
+TGGTGGCAGTTTTGAGAAGAAGCCATGCGCCAAGGTCGGTTTGCCTTCTG
+TTTTCTCATTTTTCGGTTTTTTTGTGAATTTTTGTAAATTAAAAATATTT
+TTTTATAGAAATAAAAATTCAGAAAAAAATACTGGAAGTTTCGTTTGCCT
+TCAAACATTTTTTAAAAATTCACAGTTTTTCAAATAGATGTACTTACACG
+TGGTGTCAGAGTATCTCATTTCGGCTTGATCTACAAAAAATGCGGGAATC
+TTTTGCCCAAAAAAATGTGACGTCAGCACGCTCTTAACCATGCGAAATCA
+GTTGAGAACTCTGCGTCTCTCCTCCCGCATTTTCTGTAGATCAGCGTAGA
+TCAAGCCGAAACGAGACACTCTGGCACCATTTTATTTTTTTGGGCAAAAA
+ATTCCCGCATTTTTTGTAGATCAAGCCGTAATGGGGCAGCCTAGCCCCAC
+GTGCACTTATTCCTTATGCCGAACGACACTCCGATATCCCGTTTTTACAG
+TATGACTGTGGGTTACTGTACCATTTTTGGTGCTTTTGTAATATTGTTTT
+CTTTTTCAAAAACCTAGGAAAAATTTGAACAATTGTTTTTTTTTAATATT
+TGAATTTTTTAGGCTCCCACACATTTTTGCGGGATATCGGAGTATCGATG
+TAAACGTTTTTTTTTTGGTTTTTTGTATTAAAAAGGGTTTAAGTGTTGTA
+ATAAGACATTTTGAATAAAAAATAGCTAGCGCCGCCACGACTTACTGGCT
+TCCCTCCTAAATAAAAATGGAAGAGTTTTTGCCGAACTAGGCCATTTTGG
+CTCGGCCGTATCTGGGGTAGATTTACGGCGCGTTGCGTGCCGCGTCGCGG
+CTCGATTTTAGTTGTAAAACCTAATGTATTTGTTGTCCGTGTGGAGTACA
+CGACTTTTCCACGCGTTGTCCGGCAGGCGATTGTCAATGGAGCGCGAAAA
+ATTCAATGAGGAAGGCCAGGACACCGATTCAAAGATATAACGGCCCACAT
+TTCAACAGCGGTATATCGGAGTGTCGTTATTTTAAGCTTGCACACGGGCT
+TCTGGCCTTTTTCATTGCTTTTTCGCGCTCCATTGACAATCGCCTGCCGG
+GCAACGCGTGGGAAAGTCGTGTACTACACACGGACAATTTTTTTTAAGTT
+TTATAATGAAAACCGCGACGCGACACGCAACGCGCCGTAAGTCTACCCGG
+GCCGAGCCGACACGTGGTGTCAGAGTGTCACATTTCGGCTTGATCTACGT
+AGATCTACAAAGAATTTTGCATGATTAAGAACGTGCTGACGTCACACTTT
+TTTGGGCAAAAAATTCCCGCATTTTTTGTAGATCAAACCGTAATGGGACA
+GTCAAAATGGCCTAATTCGGCAAACTCTTACATTTCAAAATATGAGGGTA
+GGCAAAAGCATGGGGAATTTGTGATTAAATTTTTGAAAAAGGAAACAATT
+TTTTCCAAATTTCTTCTGAAATTTTTTCAAAAATAAATGTTTTTTTTCCC
+TAAAATCTTCAAATTTCTAGTTTCAATCTCTCACTACCGTGACCAAAAAT
+TCCTATGATTTTTGACCTCCCGCCACACAGTTTTACCACCAACTTCTTCC
+CCCCCCACCCACCCACTTACTTCTCGTATCTGAAACTCCGCCCCATTTTT
+CGTGTACTTTACTACTACTTGAATGATGATGAGGTAGAACAAATCTGTGT
+TTATTGGCAGAAGCAGTGGTAGCAACAGGAGAAGAAGAAGAAGCATCACT
+GTGTGGAACCAGCCAGCTGTGTTGTTGTGGTTTTAGTCGTGGAGAGAGAG
+AGGACGACGTCGTGTGTCTTCAATAAAATGAGGATCTCATCGCTCTTATT
+CCTGACTTTCTTGGCTGGAATTGTTCAGGTAAGCTGGGTTTTAAGTATTG
+ATATTGGTGCTATTTGAAAATTATTTCAAAAATTTTTGGAAAATTTTTTT
+TTTTTGGCCCAAAAATTTTTTTTCTAGAACTTTATCATTCCTAGGCATAC
+TCTAAATATGTCTGCAAATATTATTTTTTCTGGAAAATTTTGAAAATGTA
+TATATGGATATATGCAAGTTTGGAAGTTTTTGTAGTATTATTTTGAAAAA
+TTATAAATTTTTTTAAAAAAAATTTTTTATAAATCTAGCAAGAAACGTTT
+TTAAAAACAATTTTAGTCAATTTTCTTTTTTTTTTTTTGGAAATTTCACC
+AAATATCGGCCCAAAATCTATGCAATACTATTTTTTCACAAAGAAATTTT
+CAAAATTTGACATTATACAGATCTAGGGCTTCCATGGTAGGCAGGCGCGG
+TTTCAGGGACCTGCCTGAAACCTACCTGGTTGCCGCCGGCCTTAATTTTT
+ACGGGAATTTAGAAAAATTTCTAATTTTCTCATTTCTATCAATTTGATGA
+AAACCAAAATAAATTGGCGAGAGGCAGGCAAAGGTTGCCTTAAGGTCAGG
+CAGGTAGGCGTTTTAACACCTACCAGCTTTACAAAAGCACTATACAAGTC
+TGTTTTTGAAATCTCTAGCTTTAAAAATCTTTAAAACAAGACATGGTGCA
+AGACAAGACAAAGACATCGACAAATTTTCGACAAAATTAATTTTTTTCGA
+AAAACTTTTAGTTTCTTCCAAATTCGCCAAAGTGAAAAAAAAGTTCCTAA
+ACGTGAGATTTTGTATGTCTTCTACACATACTAGCCAATATCAATTACAA
+TATCTGCCAAGAAAATCTCGAACCAAACACCAAAACGGCGTTTGGTAACC
+GGTTTTTTTTCCAAAAAAACTATACATAGTTTCTAGTAAACAAATACGAA
+TGGAAAATTCAAGGTGACAGAGAAGAAAAAAAGATTAGAAAAAAAATCGT
+TGGTGGTGGCCTAAGAATTGCATGTAACGTCACACCTCGGCCAGGGGTCA
+TGGTACATGCTACATGATTACCCATGGCAAAAGAGTGACGTCACTCTCGG
+CCATGATTTTTAGGTTTAGGCTTAGGTTTAGGCTAAGGCTTCGGCTTAGG
+CTTAGGCTTAGGCTTAGGCTTAGGCTTAGGCTCAAGCTTAAGCTTAGGCT
+TAGGCTTACCTTATGAGCCTATAAGCTTTCTGAAAAAGACAAATATTAAA
+AAAAAACCAAAAAAAAAAAAAAAAAAAGACAAACAAACAAATAAAAACAA
+ACAAACAAATAAAAACAAACAAAATATTTGAATTTTTCTAAGAAGACAAA
+TACGTCACTCTCGGTCACGATTTTTGGGCTTTAGGTTTAGGTATATGTTT
+AGGCTTAGGCTTAGGCTTAGCCTTAAGCTTAAGCTTAGGCTTAGGCTTAG
+GCTCAAGCTTAAGCTTAGGCTTAGGCTTACCTTATGAGCCTATAAGCTTT
+CTGAAAAAGACAAATATTTAAAAAAAACCAAAACAAAAAAAAAAAAAAGA
+CAAACAAACAAATAATTTTTCAGGCCCAAGACTTCCTTGCAATGTTCAAG
+CCGTTCCTCGGAGGTGGCGGTGGTGGCGGTAATCCGTTTGCAAATCCACA
+GGCGATCGGCGTAAGTTTTCCGACAGGCAAACAGACAAACAGACAGACAA
+TCGAAAGTGGTCCAGGCGCTGAATGTGTTACGCAATTGGTTTTGGGCGCC
+ACGCGCGCATATTATTTGCATATATACATACATCATTCAGATAAATGGCA
+TTGAAAACGAACAAAAAGTGAAGATTTAGTGGGTTGGCAAATGCATTTTA
+TGTTTCTTTTCCAGGGTCTCTTCCAACAATTCGCCGGTGGAAATGGTGGA
+GGATTCGGGCAGCTTCTTGCTGGAGCAATGGCACCGGTATGTGTTGCGAC
+GTTTAAAACGGAGTGTCGTTGTGAAATTTTCCGCTTTGGAAAACATTGAG
+AATATTCGAAAATTTTTGTAAAATTTTGAGATTTTCTTTTTCCAAGCTTT
+GGGCTTAGGCTTAGGCTTAGGCTTAGGCTTATGCTTAGGCCTATGCTTAG
+GCATAGGCTTAGGCTTAGGCTAAAGCTCATGACTAGACTTATTCTTAGAT
+TTAGGCTTAAGCTTAGGCATGGCCTTAGGCTTAGGCTTTTGCTTAGGCTT
+TTGCTTAGGCTTTGGCTAAGGCTTAGGCATAAAAAAAGAGAAATTCCCAA
+AGTAAAAAAAAAGACAACTTTTGACAAATTTGAAAGTGAAATGTTATATT
+TTAAGCCTATTTTTTCCCTAAAAAGAAAAAAATTACTTTTATAGTTTGAA
+AACGATTTTTTGGCAGTGTTTCAGCAGTCAAAAATATGGCTGAAAAAAAA
+AGTTGATTTCAAAATATTTTTCATCTCAATTAATTCTTTTAAATTTGCTC
+TACCAAATTTGAAAAAAATATTGAAAATTATTTTAAAAAATTTAAATTAT
+TAAATTTCAAGTAAATTCGAAAATTTTGTTTATTTATTTTATGTTCATTC
+TTACAATATAAATTATAATCCTCAAACATTCCAGAAACCAGCACCAGCCG
+CAGCTGGACCCCGCTCAGCTCCAGCTCCAACCAACGAGGACTACAACACC
+GACATCGACGTTCCAGCTCCAAAGGCAAAAGCCCGTGCAGCTCCAACTCC
+ACGAAGAGCACAAGGTGATGATGATGATAATATTGATATGTCTCTGACAC
+GTCTTGGCTAACTTGGCTTGGAAAAGCACAATTCCTTTAATACAAAAAAC
+TTTTCTCAAAGATTCTCAAAATTTTGCACTTTAATTTTTAAGTTTAATTT
+TTAAAAAGTTGTCTCACGTTTTTTAACCAATTTATATGCAAATATGATCC
+TTATTACTAACAATATTTAGTAATCTAAACATAAATTGGAATATTTGGTC
+TTTTTCCCGCCGAAAATGATCAAACATTCCGAAGTTAGCAACAGAAAATT
+GCAGTGAATTGTGTTGGTTTAATTTTACCGTCGTTTTTCATATTTTTTGC
+CCGATAGCTTTGCTGTGTTTTGTGCCATCCTTTTCTCTGTGATATACTGT
+TACTTACTTCAATAAATGATTCTTTTAAAAGTTTTCGCACAAAAAATTTA
+GAGTTGCTGGCAAAAATACACGCCGACACGTGGTGCCAGAATGTCTCATT
+TCAGCTTGATCTACGTTGATCTACAAAAAATGCGGGAGAATGGAGACGCA
+GAGTTTTCTATTGATTTTGCATGGTTAAAAACGTGCTGACGTCACATTTT
+TTTAGGCAACAAATTCCCGCACTTTTTGTAGATCAAGCCGTGGTGGGACA
+TCCTATCCCCACTTGCGCTGGGGGGACAAAACCGACATAACTTTTGAAAC
+ATATTACACATATACATTTAATATATGTTTTCTGAGAGAAAACGTTTTAG
+AAATTTTAGAGAATTTCAGCAAAAAAATTCTGATAGCTTTTTGGAAATTT
+ATATTATAAAATTTTTTTTTTTTTTTAATTCTGATTTTTTCAAAAAAGAA
+ATTTTGCAAACCGCTTCCAGAATATTTGCCTGTCTCAAAATACCCTAAAA
+AACATTAAAATGTTTCAAAAATTATCTTTTGGAACAATTTTACGGGTCAC
+GCGAAATACTTTCTTTGTAAGTTTTTTTTCTTTGAAATTTAGATTTATTC
+CCAATATACGTAAATTTTTCACTGAAAGTTAGAAAATTATACTTGTTTTT
+TTCCAGAAATTGAAATGTACATGATACAAGGCTGCTACATTCCAGCAAAA
+TCTGATAAAATTTTAGAAACAATTTTTTGTCAGAGTCTTGAATATTTGAG
+CTATAAGTTTTTTTTTTTCAAAAAATTAATCCAGTTTGGCCTAAAAACTT
+AAGGCTAAGATTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTCAGCCTAA
+GCTTAAGCCTAAGCCTAAGCCTCAGCCTAAGCCTAAGCCTAAGCCTAAGC
+CTAAACTTAAGTCTAATCCTAAGTCTATTCACTAAAATTTTGACGTAAAA
+CTTGGGACTAAAAATTTTGGACACAAATTTTTTACCTAATTTTTTGGTCT
+AAGCCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAA
+GTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGT
+CTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCT
+AAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAA
+GTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGT
+CTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCTAAGTCT
+AAGTCTAAGCCTAATAAGCCTAAATAGGGTCTAACGCTTGCCACTGACGC
+CGCTAACGCTCGCCACTGAAGCCACGCCTAAGCCTAAGCATAAATCAATT
+TGAAACTTCAGACTTAAATTTCTTGGTGGCCTATACGACTCTCTGTTAAA
+TTTCGCTTTGATCAGCAAACGGGAACCCTTTGAAAAATTAAAAAACTAAC
+GCTCGCCACTGACGCCAAGTCTAAACCTAAGGGTAATACTAAGCCTAAGC
+CTAAGCCTAAGCCTAAGCGTAAGCTTAAGCGTAAGCGTAAGCGTAAGCGT
+AAGCCTAAGCCTAAGCCTAAGTGTAAGCGTAAGCGTAAGCCTAAGCTTAA
+GCCTAAATCTTTCGACAAAAATTTTGACCTAAAACTTTGACCTAAAATTC
+GAGACTAAATATTTTGGACTCAAATTTCGGCCTGAATTTTTGGACTAATT
+CTGGGAACTATTCCAGAGTAATTTTAACAAATTGAAAACTTTTTATAGTA
+TTCGTAAAACAAAAAATAAATGCAATGTTTTCAGTAATAAATTTGAAATT
+TTTGAAAAATTAAATATTTCTTCGAAACTTCGAAACTTCCTTTTCTCTGG
+CATAACCCCAAATTCCAGCCGATGCCCCGCCAGTATACCGCCAGCCTCGC
+ACAAAAGCCGAAAAAATCGAAAGATTCCGGAATATCGCTCGGACATTCTC
+GCCGTTCGTGTACGAGGTGAACACCACACCAGCTCCTCACTTTGACAACT
+TCATCTGGCAACAAAATGCACCAGCTGTCACACCGGAGCCATTCACATTT
+GCTCCATTCTCCTTCCCAACTCTTGCCACCGTCGCACCACCAGCTCCAGG
+ACCCGGCGGCCCGACTCTTGAGCCATTTTTACCGACGACAGCTAGTCCGA
+AGCTGTTAGCTCATAACACTGCTAGGGTATCAAAAAATTTGAATACTGAA
+TACCTCCCTATAACTTTTTCAAATTCCAGATGATCCGAGAAATCGCTTCA
+TTTTCCGACGGAGGACGCTCCAGGGATCAGGATTTTGGCGCAGTTCAAAC
+GCTCATGCAAGCCTTCTTCGAGGCAGTCTCCAGTGGAAATAATGGTGGAG
+CAGGAGCTGCCGCCGGAGCCGGAACAGCTTTAGGAGTAGGTTAAGCTCAC
+TAAAGAGGTCGTGAAGTTTTACTATTTTTTAGGATGCTCCAATGCTTCAA
+GCCCATCGAGATGGTACCGAGTTGGGAGCCAATCGCGCGCTGACCAACAA
+GCTTTTCGAGTCGGATATGGTGTTGACGGTCAAGCAGATGAAGGCGTGAG
+TGTGGGGTACTGTGCAATAAGATTATTGTAGGGGTACTGTAAGATCTCTG
+TAGGGATACTGTAACCCTACCGTGATATTACTAAAGGGGTGCTGTAAGAT
+TACTGTAGGGGTACTATAGGATTACTGTAGGGGTACTGTAAGATTACTAA
+AAATATACTGTGAGATTACTGTAGGGGATGCTGTAAAATTTCTCTAGGGA
+TATTGTAGAATTACTCTAGGGATACTGTAGAATTACTGTAGGGAACTGTA
+AGAGTACTGTAGGATTACTAAAGAAGTACTGAAGGATTACTGTAGGGGTA
+CTGTAAAATTACTATAGAGTACTGTAAGATTTCTGTAGGGGTACTGTAGG
+ATTACTGTAGTATTACTAAACAAGTACTGAAAGATTATTGTAGGGGTACT
+GTAAAACTACTATAGAGTACTTTAAGAGTACTGTAGGATTACTAAAGAAG
+TACTGAAAGATTACTGTAGGGGTACTGTAGGATTACTGTAGTATTACTAA
+ACAAGTACTGAAAGATTACTGTAGGGGTACTGTAAAATTACTATAGAGTA
+CTGTAAGATTGCTGTAGGGATACTAGAAGATTATCGTAGAGATACTGTAA
+GATTATTGTAGGGGTTCTGTAAGATTTCTGTAGGGTTACTGTAGAATTAC
+TGTAGGGTACTGTAAAATTACTGTAGGGGCACTCTAAGATTACTGTAGGG
+ATACTGTAGAATTACTGTAGGGTTACTATAAGTTTACTATAATATTTCTG
+TAGGGTACTGTAAGATCACTGTAGAGGCTACTTTAAGATTCCTGTGGGGG
+CACTGTAACACTACTGTAAGATAACTAAAACGGTACTGCAGGGTACTATA
+AAGCGACCACCCTAGATTCATGGTTATTTCAGAATTGTGCTCGCCGCCCA
+AGAGGCCCGTAACCCTCACGGACGTAAAAAGCGAAAGGTGATTACGGGAT
+CCGTGTACCGATGGAAGAGTGTGATTCCGTTCCGATTCAAAGGTGGCGAC
+GCGAAATGGAAGAAGCTGATCCGTGAAGGCCTAGGCCTATGGGAGAAGGA
+GACGTGTGTGCGATGGAGCGAGAATGGCCCCGGCAAGGATTATGTGATCT
+TCTTCAGAGGATCTGGGTGAGTTGACATGCCCATGGTTTTCGGATAGTTT
+GGGTTTTTTTTCAGATGCTACTCATCAGTCGGAAGAACCGGAGGATCTCA
+ACTTATTTCGATTGGGTATGGCTGTGAAGATGTAAGTTTTAGTATTTCTA
+CTATACTATTTATTTTAAATTCAAATTTTCTAGAAAGGAATCGTTGCTCA
+CGAAGTCGGTCACTCCCTAGGCTTTTGGCACGAGCAGTCCCGTCCGGATC
+GGGATGACTACATCCATTTAAGAAAAGACTGGATTATTAAGGGAACCGAT
+GGAAACTTCGAGAAACGAAGTTGGGAAGAAATCGAGGATATGGGCGTTCC
+GTATGATGTCGGAAGTGTCATGCATTATGGGTCGAATGTAATTTTAAATT
+TTGAGTCGGTAGTTTTTAGATACTGAAAATGATTTTCAGGCTTTTACAAA
+GGACTGGGACCAAATTACTATTGAGACCAAAGATAGTAGATATCAGGGAA
+CGATTGGTCAACGCCAGAAGCTTTCGTTTATCGATGTTAAGCAGGTTAAC
+AGGCTTTATTGCAATTGTGAGTTGTTATGCAAAAATGAAAAAAATTTGAC
+CACTGAGCGGATCGAACGCCCAACCTTTCGATCTGGAGTCGAACGCGCTA
+CCATTGCGCCAAGCAGTCACATTTTGTTGCAGGAAACGGTGTATAGAGGA
+GAAAAGAAAAAAATAGACAACCCTACGTTTTATCAGTGGAGCGCGGTTGC
+AATTTAACATTCCAATTTTCAGCTGTTTGCCCGGTTGCCTTACCCTGCAT
+GCATGGAGGATACCCCGACCCCAATAACTGTGCGGTTTGTAAATGTCCAG
+ACGGGCTCGGAGGAAAGTTGTGTGGACGTGCCGCAAAGGGCACAGATCAT
+GGTAAAACTCCACTGGAATTTATGGGAAAAAACCGCCCTAAAATTTTCAG
+ACAAATGCGGCGGTGAGCTAACAGCGACCGCCGAATGGCAGGAGATGGTC
+TACAAGGGGAAGCGGACGTGCAATTGGAAGGTGAAGTCGCCGAGCGGTGG
+GCGGGTTCGGTTGGTGCTCACCGAGCTCAGGTACCAGTGTGCACCGGCGT
+GTAAGGCCTACATCGAGATCAAGCATAATACCGACTTCCAGCAGACCGGA
+TTCAGAGTTTGGTGAGAACCCTAGATTCCCAAAAAATTCTACACTTTTTT
+CAAAAAAAAATCGAAATTCGACCCATTTTGGCGGGAATTAAAATTCTTTT
+AAAAATGACAAAAAAAATATTTTTCTGCAGAAAATTTTTCGACTTTTTAG
+AAAGCAAGCTTTCACGCGGTTTTGGCTTCCCTCATATATTGAAATGGAAG
+AGTTTTTGCCGAACTAGGCCATTTTGGCTCGGCCATATCTGGGGTAGATT
+TACGGCGCGTCGCGGCTCGATTTTAGTTGTAAAACTAAATTTAATTGTCC
+GTGTGGAGTACACGACTTTCCCACGCGTTGTCCGGCAGGCGATTGTCAAT
+GGAGCGCGAAAAATTCAATGAGAATCGAGCCGCGAAGCGACACGCTACGC
+GCCGTAAATCTACCCCAGATATCGCCGAGCCAAAATGGCCTAGTTCGGCA
+AGCTCTTCCATTTCAATTTATGAGGGAAGCCAGAAATCCGTGTAAATTTT
+TAATTTTTTGTTGCTTAAAAAAAAAAACTAAACAACTATTTTCCAATTCA
+AATTTCTAGCTGCTTCAACAAAACATATGACGTCATCTCCGACCAATCTG
+AAGCCCTGATCCTCTCCAACGCGAACATCGTGGACTACGAGGTCTCCTAC
+AAGCTGCAATGGATTCAAGGTACCCCACCCCCCCCCCCTTTTCTATCCAT
+AGAGCGCACTTTCTTCCAGACAACGGAAAAGCTCTTCCACCACCGAAACC
+CACGTCGACCTGGGTGCCCGGAAAAGAGAATCGACCATTCCGCGGAGTGG
+AGAACTCGGGCGGCACCATCGAAAAGTTCATCCTGCAAGCGATCCCAAAG
+ATCCGAGACTCGCATCGGCCACTGGAGAGTATTACTAGTATTGTTGCGGA
+ATATGGTCTCGCAACGCTACTTGGTATATCGCATAATGGAAAGTAGTCCG
+TTTGGAACGATTTTTGCAATCGTCAGAGGAATATATATATATATTTGTAA
+ATTTTGTACCATCCCAAAAATCCAATTTTTCTTTCACAATTTTCAAAATT
+TGCTCATCTTTCACAATTACTCGGGTTAACACATTTAATGCCTTTCAATA
+AATAACAGTTCATATTTAAAGTGATTATTATATTACAGGAACACATATAT
+CTGAGAATGCGTATCGCACAACATATTTGACGCGCAAATATCTCGTAGCG
+AAAACTACTTTAAAAGACTACTGTAGCGCTTGTGTCGATTTACGGGCTCC
+TTTTTTGAAATTTACACGGTTTTCTGGCTTCCCCTCAAAAATTGATATGG
+AAGAGTTTGCCGCGAACTAGGCTATTTTGGCTCGGCCATATCGTTCAAAA
+ACTACAGTAATTCTTTAAATGACTACTGTAGCGCTTGTGTCGATTTACGG
+GCTCCATTTTTGAGATTAATTTTCTTTCGAGTTCCCTTCGTTTTTTTTGT
+AATTTTTTGCTTAATTTGAATTTTTTTTTGATAAATTAAAAAAAATGATT
+TTACACGGTCTCCTGGAGTGTTCATAATTATTGGAGCGCACTTGCTGATC
+CTTGCCGCGCTTATTTACTTTTTCACCGTTAGAAAATGAGTAAAATCAAC
+GATTTTGGTCAAGAAATTTAAAATAAAATTATTAATTGATTTCAAAACCG
+AGTCCACGTGGTGCCAGACTGCCCCATCACGGTTTGATCTACAAAAAATG
+CGGGAATTTTTAGCCCAAAAATGTGTGACGTCAGCACGTTCTTAACCATA
+CGTTGAGAGTTGAGAATTCTGCGTCTCTTCTCCCGCATTTTTTGTAGATC
+TACGTAGATCAAGCCGAAATGAGACACTTTGACACCACGTGCGAGTCCGT
+AAATTGACACCAGTGCTACAGTAGTCATTTAAAAAATTACTGCATGTCAA
+AATTAAAATTTCCTGTTCCCGTAATATCGGATTCAGCACGCCACCCTATG
+AAAATACCAAAATTGGAAAAAAATCAATAAAAATTTATTTTCACGGAAAA
+AAAATTGAGACCACCTTTTTGTTTTCTATCTATATAAACCCGTTGTTTTT
+CACAAAAAATTATTGAAAATCCTTCAAATCATATTATTAGTTCGAAACGT
+CGACGCGTAGGTGTTCGATCGTACACTGCCGGGAATTGCCGGTTGCGGGA
+GTTTCGGCACCGCCGGTTGATATCCTTCTTTGCTAACTTTTGATCTGAAA
+ACATTGACTTTTGCTACGTGGCCGTGGAAGAGAAAACTCGGCCACTATGT
+TTGTTTTTGCGACAAGGGTATATGCGCAAACCTACAAAATGATCTTCAAA
+AAATGCGCGAATTTTTTGCCCAACAAAATGTGACGTCAGCACGTTCTGAA
+CCGTGCGAAATCAGTCCCGCATTTTTGTAGATCTGCGTAGATCAAGCCGG
+ACCACAAAAATATCAAAGTTTTGAATTTTTCAAAAAAAAAGCACTTACGA
+GGATCTAGTCAGCTTGAACAGCAAGTAAATAAGACAAAACGCGCACATGA
+TGAAGCTCAAAAGTAGATCAAACGAGAACTTGGTCGCCGAGACCGCATTG
+AAACTTCTGTCAAGTGAGAGAAACGGTTGGGTGGCATCGTTCACAAATGA
+AAGCATGTAGAATAGTCCAGCAATCGGATAGACTGCCGCAATGACTCCGG
+CAAACCCATTGACATCCTGCTCATCAGAGCCCAGAAGCCGGCAGCAAGCA
+GACGAAAGAGCAATGGAGCTGATGAGGAATAGAATGAGCTCCCGGCAGAA
+GTTGAAGATCCAGTCGGTGCCCGGGCTTGCTGCTCCGATGAAGCAGAGTC
+CGGTGAGGGGATTGGCGGCGACGGCTTTTGCGAGTAGCGCGAGCATTAGT
+GGAGCCAGCGGGATTCCCAGGATGAGCATGATCACGCGGGTTCTGGAGTC
+GTCCTGGAAGATCATTTTTTAAAATTTAATTTTTGAAAATTTATCATGTC
+TGGAAAAGGTACAGGCTGACTAGACCTATTTCACGTGGTGTCAGAGTGTC
+TCATTTCGTCTTGATCTACCATGATCTACAAAAAATGCGGGAGAAGAGAC
+GCAGACTTCTCAACTCTCAACGTATGGTTAAGAACGTGCTGACGTCACAT
+TTTTAATGTACAAAAAATTCCCGCATTTTTTGTAGATCAAACTGTAATGG
+GACAGCACAAAATTCAAAGCCCTCACCAATATATGCGATGTCCTTGTCGC
+CTTATTCCACGACACACAGATCAAGAGCCACCAGAGACGTGAGCAAGTTG
+CCGTGTAGTAAATCAGTGAGGCCACTGAAGAACATGGAACATGGGAAAGC
+CCTCCGACGACGAAGAGCAGGTGATGGGTGTAGTCGGTGCACGAGATTTG
+GAACTTCAAAATTCTTTTTGAATGGCTCAAAAATATTGATTTTGAGCCAA
+GTTATGACCATTTGAAGTTGGTGGCCTAGGATTTTCCTAGGAGTATTCTA
+GGCCGCCAACTTTGGACAGCCATAACTTGGCTGAAAATCAAAATTTTTGA
+AATCTAATTTCACAGTTGAATTTAGCAGACCATGAGCTTCAATTTGACAT
+ATTTTTGTGCCTTGCCACGAAAACTCGCAGACCTACAGTAATCCGGCCAA
+AATTAATGTTAACTGAAAGCTCAGAGTCTGCTAAATTTAAATACAAAGTT
+CGATTTCCAAAATATCGATTTTCAGAAAAATTATGAAGACTCTAAGTTGA
+TGGCCTAGCATTTTCCTAAGAGTATTCTAGGCCGCCAACTTCAAACGCTC
+ATAACTTGGCTCAGAATTAATATTTTCGAGCAAAATAAAAAGAATTTAAC
+ATAAAATCTTGTGATCTACCGGAAACTAGATGAGCGCAATTTTAAATATC
+TAGGCCACCAAGTGAAAACCGTGACTCGGCTCAAAACCATTATTTCTGCT
+TCAACCAAAAACCAATTCATTTATTTTAATTGAAAGCCCGGTGTCGGCTC
+AATTCAAATACCAAGTTTATTTTCAAAATACCAATTTTCAAAAAAGCTAT
+GAGCGTTCTAAGTTGGTGGCCTAGGATTTTCATAGATTTTCTAAGCCACC
+AACTTCAAACGCTCATAACGTGGCTTAAAATCAATATTTTCGAGCAAAAT
+AAAAAGGATTTAATATAAAATCTTGTGATCTATCGGAGAATGCATTTTAA
+ACTTTCTAGGTCACTAAGTAAAATATTCGGCCACCAAGCCTCGGCCGAAA
+ATTATTATTTCTGCTGAACCAACAACCAAATTCTCCAAAAACTGCTTACC
+TGATCTTTAAACGAAATGCTCACAATATAAATAACCGATGTCGCACAAAA
+CGAGATGCACGAGAAGAACATGGCAGTTTCCGTAAGTGAGTGGAGCATCT
+CGAGACGTCTAAAGTAGATCCTGATTTGTTTTTGGAAAATTAGGCCACAC
+ATCACACAATCCAAAACTTACGATAAGCCGACTATGAAGACTGATAGAAT
+TGTTAGTATTACAGAGCTCAGCGAGAGAAACAACAAGAGTCGGGTGGCGG
+ATTCACGGTCAGTCTGGAAATGTACTCATTTGTTACTGAACTAGGTCTAC
+TTAAGCCTAAGCCTAAAGTAAGCCTACCTGCCCAACCTTCTGTGGGTTCG
+AGCACAAAGGCACACACTTTGAGGATCGATTCAGGAACACCTCATCCTGT
+GGGCATTTTCCGTTGAGGCGGTCGACCTCCCGTTGAATATCTTCTACTCG
+ATCATTACCGTCGTCCTCCTGGAAAAGAAAGATGATTGATTTGAAGCTGT
+GTATCTAATTACCCCCGTTTGATGATATAGGACCGGAGAGATTACAATCA
+GATGTTCTCTGTTTTTCTCTGTTTTTTGGTAGCTAGTATAGAAAACTATA
+GAGTACTGTAATTCCTATTTGGGAGCTTGGTATTGTGCTATTATCAAAAA
+AATACAATTGCACAAATTTCTCATTGATCTACCTGTTGAACTTGACTCCG
+CCCCCAATCTTGTTACTGTTATTATTAAGGTAGATCAAAAACACAAGGAA
+GATCAAAAATAAATTACGAGAAAATTGTGCGATTGTATTTTTTTCTATAA
+TATCAAACATTTATTGATTTTAGGACATTCTGTGATTAACTTTTATAGTT
+TCACGGATTTCTGGCTTCCCTCAAAAAATTGAAATGGAAGAGTTTTCGCT
+GAACTAGGCCATGTTGGCTCGGCCATGCGTGGCGCGTCGCGGCTCGATTT
+TAGTTGTAAAACTAAATATTTCCCACGCGTTGTCCGACAGGCGACTGTCA
+ATGGAGCGCAAAAAATTCATTGAGGGAGGTTTCTATTTGGCAATGCGCTT
+TTGGTTTTTCAGTGATCTTTCAAAAAATTTTTCATAATTTTCAAATGATC
+ATAACTCTGAAACTAAAATTTTTGGCAAAAAAAGTCGTAATATTGTAAAA
+TGTTGCTCATAATTTCTTCTATACGATAAAATTTTTTCAAAATTTTACAT
+TAAACAGGCCAATAGGTACAGCGCCCGACAACTCGCGGGTCCAAAAATTT
+TTCAAAAATCGTCAAAATTCGACTCGCGAGATGTCGAGCGCTAAATCTAT
+TGACTTTATTTTTTTGAATTTTTGAAAAATTTGTTATCCAATAGAAAAAT
+TTATGAGCAACATCTTATTAGTTAAGCGTTTCTTGCCAAACATTTTATAT
+TCAGAGCTATACTCATTTGAAATTTTTGAAAAATCACTGGAAAACCAAAA
+ACGCGGCAAACGATTTTTTCCGGCAAATCGGCAAATTGGCAAACTGCCGG
+AATTAAAAATTTCCGGCAAATCGGCAAACCGGCAAATTGTCGAATTTGCC
+GAAAATTTCGGCAAATTGTGGTTTTGCACTTTTTTTGGAAATTTCAGAAT
+TCCAATTTCAAATTGCAAAATTAAACTCATCCTATGAATGTTTCTACATC
+TATTTTGAAAAGTAAGTAAATTCTATGAAAATATATAAGGAAAACGAGAA
+AAAATTCAAAAAGACATAGTTTTAAGTGTTTCCGTCTTATTAAAAAATCC
+CTCTAAACTTTTCCGGCAAATTGATATTCGGCAAACGGGAAATTGGCGAT
+TTGCCGGAATTGAAAAACCCGATACTTACACTTTCTTTCGCTGCAAACTT
+TGCCCTCTCATCTTGAATTGCTCCTTGCTCATTTGGCCCTTTCATGCACA
+TTTTCTCTCGATTGTTCTCCAACGGGAACTTATCACAACGAATCACATCG
+GGCCACTTGAAACCGAAACTTTCCAGCACTGGAAGACACTTTTCCTGGAC
+GGAAAGACACAATGGACGGCATGGACCAATTGGGTTGGCTAGCTGAAATT
+TTTTTGAACGATGAAATGATAAAAATGTGCGATTCTTCTCTGATTGAACT
+CACTTTCTCGTTGCACATCGGGAAGTAGACGGAGCACAGGAAGAATTTGA
+GCTGCTCGGAGCAGACAACGGAGAGCAGGGGCTTGTAGGTGAGGATGGAT
+TCGGAGGCGTCTTTCCATGATTCCTCGTCGACGAGATTTGGGAAGCTGGA
+ATAAGGGCTTGTAAAGTTTGAGAAACTTGAGATTTACAGGGTCAAAAATT
+GCTCACGAGCTCTCCCGGTTGCCGAAAAGTTGCCGAAATTTGAGCAACCA
+AAAGTTGCCGATTGCCAAAAATTGTAGGGTACGGCAACTTCGGCAATCGC
+CGGTTACCGAAGATTTTAGAGTTCGGCAACTTCGGCAATTGGCGGTTGCC
+ATTGCTCTCACGAAATTTCCCGCTATTTTTGGAGATTAAACAGCAAGTGC
+ACGTGTGGGTGTCTCAAACAGGAAAGAAATCCTGGCAGGAGCCGACTTGC
+CGGAAATTTTCAATTCCGGCAAATTGTCGGTGTGCCGATTTGCCGTTTGC
+CGGTTCTCAGATTTGCCGGAAGTGTGTAGAGGGATTTTTATAAGACGGGA
+ACACTGAAAACTGTGCCTTTTTGAATTTTTTCCCGTTTTCTTTGGATATT
+TTCATAGAATTTGCTTACTTGTCAAAATAAATGTAGGAACATTCATAGGA
+TGCGTTTAATTTTGCTATTTGAAATTGAAATTCTGAAATTTCCAAAAAAA
+TGAGTACAAAACCACAATTTGCCGGAATTTTTCAATTCCAGCAATTTGCC
+GATTTGTCGTTCTGCTGGTTTGCCGGAAATTTTCAATTCCGGCATCTTGC
+CGATTTGCCGATTTGCCGGATTGCCGAAAATTTTCAATTCGTTAGCCGTC
+CACCCTGGATCCTGCCATCCAAAAAAAAACGGAAATTTTTGGCAAATTGC
+CGTTTTTCCGCCGGCAAATTCGGCAAATCGACAATGTGCTGTTTTGCCGT
+TTTGCCGGTTTGCCGGAAATTTTCAATTCCGGCAATTTGCCGATTTGCCG
+ATTTGCCGGTTTGCCGGAAATTTTCAATTCCGGCAATTTGCCGATTTGCC
+GATTTGTCGGATTGCCGAAAATTTTCAATTCCGGCAATTTGCCGATTTGC
+CGATTTGCCGGTTTGCCGGAAATTTTCAATTTCGGCAATTTGCCAATTTG
+CCGTTTTGCCAAAAATTTTAGGGTTCGGCAAATTCGGCATTTGCCGTTTT
+GCCAAAAATTTTAGGGTTCGGCAACTTCGGCAGTTGCCGGTTTCCGCACA
+TCCCTGTCCCACACGCCCCAGGTGGAAGATGGTGGAAGAGTTTCTAGCGG
+GTCCATCAAGGATGGGAATCATCAGTCAACACAATCCTTAGCCGACCTTC
+CCAAATTCATCATTCCTTCCTTCCAAAACGGTTTCCGGTCCTTCCAACCG
+ATTAATACCAGCCACCACCACACCACCAAACCCTCTCCTTCGAAATAGAG
+AACAAAGTTGCATACCCCCCTCATTTCTTTGTTTTGGAGAAAGGGGCGTT
+TTGTGGTGCTCGGAGAGCCTGAGGACGTGACAAGTGATATATAGACGGGC
+TTATACTATCTGCTCGTCCATATTTCACGCGCCTAGGCAGAGTGCACGGC
+GGGAGGTGGAGACGCAGGTTCCCGTCCAACTGCCGCAGAGCATCCCCTAT
+CTGCTCCTATCAATTGTTCGGAGAGACTTTTTTGTGAATTTTGCTTTTTG
+CAAGAGGTCTGAGATTTGGGATTTGGGCTTTAGGCTTTAGGCTTTGGGCC
+TTGCTTTGCGCCAGAGAATGGAAATTTGTCCGTATTTTCCCGGCTTATAT
+CAAAAAATGATCAACTATAAAAATATAGAAAAAGATTTTTCAAGTTTTTT
+GTCAGTTAGTATTTTTTGATAAAACAAAAGAGAGCCGAGATATAAGCTGT
+CAAAGTAGAGCAAGGGTGGTTTGATCTACAAAAAATGTGGGGATTTTTTT
+TCAAACTTGCTCTACTGATAAATTAATAAATTACTCCCACAAAATCCAAT
+AAGCCTCAAACTTAAGATCCTCCAATCTCATCCCCCTCATAAAACAATAA
+TACTAAATCACTAGATCTCCGGTAGTATATATCAGAAGAACAGTTGCTCT
+CCCTCTCGAACCGACTTACACTTGAGAAAAATAAATTGTGGAAGAGAAGT
+GACGTCATCGTAACCTACCACTTCACAAGTTTATATATATATATATATAT
+AAGTACTAGTTAGGACTAGCTAAGACCTAATTAGAACATAGGTATGGCCT
+GTAAGTTAGGACCTAATTAGAACTCACTAGGACTATATATATATATATAT
+ATATATATATATATGTAAACAAGAACCCGGGCGGGTAACCCCTTACGGTC
+AGAGGGGTGTCCTACACCAAGGGTATGTAAACTGTGTCCCCCAGATGGCG
+AAGTTGAGAGGGAAAAAGTGAAAAAGCGCGCCACATGGCCTCGCGACCGT
+ATGTTGCAATTTCAAGCAACGTTTTTGATTTATTGGAGGAGAAATTTTGA
+AAAAGTGAAAAAAAAGTGTGACCCCATATGAGATGCGTAATAAAATTCCC
+TACAAGACCTTAAGAAAACGTGGCTGGCTGGCAAAAAACAGGTGGCAATA
+ATAACGGAATGTGTATGTGTGTGTGTGTGTGTGTGTGTGCTCGAAGAGCA
+TAGGCTCGTAAATCGTTATAATTGATGCTGGAGGAGAAGGAGACGATGGG
+CCTCCAAAGTGTTACACCTGGTATTTGTTGGGAAAAATTTGGGGGAAATA
+GGCATTAAACTACCTAACCTAATTGAGTTTTTTCAAAGCTTATATTATTA
+TAACTAAGAGGTGTGATAATAAATAATTAAAGAACTTTAAAATTATCAAA
+AACGCTTTCAAATCTGTAAAGCTGATATTTTAAGGATTTAGTACTAGTTA
+AAATCTAGTTGGGACCTAGGTAAGACTATCTAGAAAGTTCGGACGTAACT
+ATTTAGGAACAGTTAAGTCTTAAGGCCTGCTTGGGTACAGGTAAAAATGT
+TTAGAAAGTTAGGAACTAAATAGGTGAAGTAAGTACTAGTTAGGACTAGT
+TAAGACCTAATTAGAACCTAGGTAAGGCCTGTAAGTCAGGACCTAAATAG
+GACTTACTAGGACTTAGGTAAGACTAGTTAATGTCTTGTTAGGACTAGTT
+AGGACTAGCTAAGACCTAATTAGAACCTAGGTACGGCCTGTTAGGGAAGA
+TCTGATTAGGACTTACTAGGATTTAGGTAGGACTAGTTAAGATATAGTTA
+GGACTAGTTAGGACTAGTTAAAATTTAATTAGAATCTAGGTATAGCCTGT
+AAGTTAGGACCTAATTAAGACATACTAGGGCTTAAGTAGGACTAGTTAAT
+ACTAGTTAAGAACTAATTAGAACATAGGCACGGTCTGTTAGTTAAGGCCT
+AATTAGGACTCACTAGGACTTAGGCAGGGCTAGTTTAGTTATTGTTAGGA
+CTAGTTAGGACTAGTTATGTACCTAATTTGGACTCACTAGGACTTAGGAG
+GACTAGTTATAATCTTGTTAGTAATATTTAGGACTAGTTAAAATCTAATT
+AGAACCTAGATATATCCTGTAAGTTAGGACCTAATTAAGACTTGATTTGC
+TAGGATTTAGACAGGACTAGTTAAGATATTGTTTGGACTAGTTGACTAGT
+TAAGACCTAATTAGATCTTAGGTACGGCCTGTAAGTTAGGGCCTAATTAG
+GACTGAATAGGACTAAATTTCTTGTTACGAATAGTTAGGACTAGTTAGGA
+CTAGTTAAAACTTAATTAGCACCTAGGTACGGTCTGTTAGGGAATACCTA
+CTTACCAGGCCTTAGGTAGGACTAGTCATGACCTAATTAGAACCTAATTA
+GAACCTGGGCACGGCCTGTTAGGGAAGACCTAATAAGGACTTACTAGGAC
+TTTGGTAGGACTAGTTAGGACAAGTTAAGACCTAATTAGAACCTTGGTAT
+GGCCTGTAACTTAGGACCTATTTAGGACTTACTAGGACTTAGGTAGGACT
+AGTTAGGACTAGTTGGAAGTTGGGACCTAACTAGTTAGACCCTTAATTTT
+GTACACATGCTTATTAATATCAATAAAAATTTTAAAAAAAAACGACTTTT
+TTAAGTTTAACTATATAAAACTATAATTTGGAAAATTTGCTACTTTGCTT
+AAAAATCGAGAAAAAACCTAGCGTTTCTATAAAAAACCATCTTGAAGTAA
+ATTTTGAAAAAACCCCGTCATCCAACAAAAAAAAATTCACTCACCTCGTT
+AAGTTATACGGCAAATCGTTGCACATCTCATGATCCACCTTTTGACACCT
+CTGCCCGTCCACACCAATCACAAAGAGCAACAGGAGCCAGGTTACTCCGA
+GGTAACCACGAAATGGTCCCATTAATGATAATGGAATTGGGGGCTCACAG
+CCTGGGTGGGGGAAAATATTGAGAGTAAAAGAAACAATGAGAAGAAAGAC
+GGAGGATAGGCGGGGGGGGGGGGGGGGGCACACCAGTGGCAGCACCACCA
+CGGCCTGTCCGTTGACAAATGACCCAAACGGACGGGGGGCGGGAAGAGTG
+TCTGTTGTGTGTGTTGGGAGATGGCTGGCGGTTATCAGATATTTGTATGA
+ATGGTATAGAGAAACAGAGACCAAGAGAGCTGAAAGATGGAGAGGCGAAA
+GAGGAAGAGAGGGGGGGGGGTGGAAGTTTTTACGAGCCCTGTAATAAATA
+TATCGAAGCAGCAAATCATTTGATGATAACGGAGGAGCGCGGGGACGGAG
+ACGGCAATCATCATCATTATTAGGACCAGGGGTGTGCGGCGAATTTTTGC
+CGAATTTGCTGTTTGCCGAGCTCGGCAATTTACCGAATTTGCCAAGCTCG
+GCATATTTCAAAAAAGTAGATTTGCCAAATTTGCCGAACTTGGCATATTT
+CAAAAAAGTAGATTTGCCGAATTTGCCGAGCTCGGCATATTTCAAAAAAG
+TAGATTTGCTGAATTTGCCGAATTTGCCGAGTTTGCCGAGTTCGGCAAAT
+TTGCCTATTTAGCCGAGCACGGCATATTTCAAAACAGTAGATTTGCCGAA
+TTTGCCGAATTTCCCGAGCTTGGCATATTTCAAAAAAGTAGATTTGCTGA
+ACTTGCCGAGCTCGGCAAATTTGCCTATTTAGCCGAGCACGGCATAGTTC
+ACAAAAGTAGATTTGCCGAATTTCCCGAGCTTGGCATATTTCAAAAAAGT
+AGATTTGCTGAACTTGCCGAGCTCGGCATTTTTCAAAAAAGTAGATTTGC
+TGAATTTGCCGAGCTCGGAATATTTCAAAAAAGTAGATTTGCTGAACTTG
+CCGAGCTCGGCATTTTTCAAAAAAGTAGATTTGCTGAATTTGCCGAGCTC
+GGAATATTTCAAAAAAAGTAGATTTGCCGAATTTGCCAATTTTGCCGTTT
+GCCGAATTTGCCGAGTTTGCCGAGCACGGCATATTTCAAAAAAGGAGATT
+TGCCGAATTTGCCGAATTTGCCGAATGTGCCGATGCCGAGCTCCTGTTGA
+TTTTTTTCCAAAAATTCAGTAAAACGACACAAATTTGTTTTAAGAATTCA
+TTAGTTTCGGTGCTCCAAACAACATCAAAAAATATCAAATTTTTCCGAAT
+TTGTTAAGCACGGCAAATTTGCCAAATTTGCCGAATTAGCCGAGCACGGC
+TAATTTTGAGATTTGTCGCACACCCCTGATTAGGACCGAGAAAAGGGCCT
+AACATGATTTCACAATTTGAAAAATGAAATTCAATTTTTCTTGGGAAAAA
+AGTATGAATCTCTTCCTCCGCCCGTTTCCGGCAGAAACAATTGAACCAAA
+CGAGCCAAAAGTGCACATTGTGTAACTTTGTTGGGGAGTGTAGATAACCA
+GAAGAAACAAGATGGAACTTTCTTGCGATGAACAAATTTTGGAACACTGG
+AGGGAAATGATTGGTGTTTTTTAAGCTTTTTAGTCAATTTTTAAAACTGT
+TCTACAATAGGCCCAAATAGGCCTAATAGGCAAATAGGCCAAGTAGATTA
+AATATGCCAAATAGGCAGTATAGGTTGAATAGGTAAACAGGCCAAATAGG
+TCAAATAAGCTAAATAGGCGAGACTGGTGCTCAAATACTTTTTGAACTGG
+TAATGTTTTTTCTTCTACACAAAAACAAAAAAGTCCCTGCTTAGTTCCGC
+AAAATTGTGATTTTTTTCAAAAGTTACCCATTTTTGCCACTTTTCAATAG
+TTTTTGATAGGTTAAATCTAGATTTTCTGAATTCAGCATATATGAATTAC
+CCGTTTTCAACAAATTTAGGCAAATTTTTATTTTTGCCCAATTTTTTTAG
+CCATCTAATGACTGATTTTGGGCAAAAAAAATTTTCCTGAAATTGTACAA
+AACCATTAGAAATTGAAAGGCTCCTCAGTTTAAAGGCACATGAGGTTTTT
+CGGAGTGGGTGGCAATTGTCGTTCGGCAAATTTTTTGGTCGACAAATTCG
+ACAAATTGCTGGTTTGCCGATTTGCCGGAAAGTATTTTCTTACTTTTCAA
+AATATATGTACGAACATTCAGAGGATGCTTACAATTTTGCCGGATAAAAT
+TTAAATTCTGAAATTTCCAAAAAAAATGTGCAAAACCATAAATTGCCAGA
+AATTTTTAATTCCGGCAATTTGCCGATTTGCCGATTTGCCGTAAATATCA
+ATTCTGGCAAATTGAAGATTTGCCTTATTTGCCGACTTGCCGCATTCCCT
+GATGTAGGCATCAAAACGACTGAACACCAAGTTTTTTTGAAATTTTTTAA
+GTTTACCTTTATAATTTTTAGTGCTCAAAAAGTTCCAAAATTAAATAAAT
+TTTGAAATTTGCCGAGCTCGGCAAACGGCAAATTTGCCGCACACTCCTGT
+TTCAAATGTTCACCGCATATTTAATTATTCCGGAAATCCCCTCAAACATC
+CATCAAAAGTGTTTTCCCTGATTTGTTGACTCTGACACCGACGGTGGTTG
+TTCCCCCCCCCCCCCACTCTCTCAATTGGCATGTAAATGAGCCCGTATGA
+ATGAAGTGCCTTTTGGCGGCAAAATGCATATCTCCAAGTACCATTGAATT
+AATCTTCCATCCCCCATTGTCTCCTTCTATATAGGGGGGAGGATGCGTGA
+TTCTTGAAATATGCTCCAAGTGACAAATTGAGCGTGTGTGATGTATCGTG
+GCAGATGGCTGGCTGACAACGGATCAGTTCCAAAAACTGTATCAAACGGG
+GGGAAGAGAGGGGAGATGAAGGATGGGGGCAGATGGAGTCATCGATGCAC
+CATGTTTTTTGGAGCTGTTCACTCAGATATTAGGGTATTTTAATCCCCTT
+TTTAAGGTCTATTTCTGATCGTAAAACTTGGTATTTTCAACTCATTTTTA
+ACTCAAAAATTTCAAAAGTTTGAAAAATTACACAAAAACCTAAATTTTGA
+TCTGGTTTCAGGCATTTTAGTCCCTGTTAAGCGTCTTCGATGCACCATGT
+TGTTGTTCAACTTGTTTAAACTTTTTAGTTCCGCATCGAGGAAAATGGAA
+AATAAAAAATTATTTATGTATTCAAAAACCATACTTTGATTCTCCGTAAC
+AACGCTTTCATGGGAGGCAGGCCCGGTTTCAGGGCCTGACGCCTGCCTCA
+AACCTGCCGGCCTCACGCCGGCCTCACGCTTCATTTCTGCATTTTGGCGA
+AAAATCAAATACTTGGACATAGTGAAAAGGTGATTTTTTCGACGCGGCCG
+ACACTTTTCGGGTTCCGCGCCGCACTATACAGGAGGCGAGGCTCGCGGCG
+CGAGGCAGGCGGAGGTCGCCGCAAGGCAGGCGCGGCAAGCATTTTTGTGC
+TTACATGGATACCCTAGTCTACACAAAGCACGAATTTCTGGCTTCCCTCA
+TAAATTGAAATGGAAGAGTTTTTGCCGAACTAGGCCATTTTGGCTCGGCC
+ATATCTGGGGTAGATTTGCCGTCGCGTTGCGTGTCGCGTCGCGGCTCGAT
+TTTAGTTGTAAAACTAAATTTATTTGTCCGTGTGGAGTACACGACTTTCC
+CATGCGTTGTCCGGCGGGCGATTGTCAATGGAGCGCAAAAAATTCAATGA
+GAAAGGCCAGAACCCAGTGAAAAAGATAATTTGACAATTACAAATAATGT
+TTTAAAATTTTTTTTTTGTTTTTGATTTTTGGTTCTCCTTGTGTTTTAAG
+AACATGATGCATCACCGCTGGAAATTGCTGGATATGTAAAAAAATTATTT
+ATGTACATATTTAAAAATCAAATCTTGATTCTCCGGGATAGAAGCATAAA
+TCAAATTTATTACTGTAAATTTTCACTTTCAGTACATTTAATTGAAATTT
+TTAAGCTTTGAAGTTCAGGGTATCATAGTTTTGCCTCCAAAATCCACTTG
+CCCAAAAAACAAGCCTGGGAATTCCCGGCGGGGGACGATGGTTCGATAGC
+ATCAATCATATCTGTGTGTGTGTGTGTGTGTGCAAGGCGGGGGATGAGCC
+GGCGCGCGAAACGAATAAATCAAGAAACGTCTCTCTTTCTGCGAGCACGG
+ATTTTGTTGTGAGCCCGCGCGCGCGCGGTCTATAGGAGGAGAGGGGTATC
+ATGCACTTCTAATACAGGGCATACTTCTTTCATTTCCATGTTTTTGTACA
+TGTAATAAAATTGTTAATTAGCCAAAAGTGGTTCACATGTTCACGTCGTA
+AACGTCGGTTTTCAGGGTGTACTGATAATGAATGTGCTCTGTGTGGAGAC
+AAAGAGGCAGCAGAGAGCAAGAATCAGTTAGGTTAGGCAGGTGACTTTTT
+TCAATTGTGACTAGGAAAAAGTATTTTGGGAATTTTTTTTTATTTTTTGG
+CTTCTGCCCAGATTTTCAGGATTTTTCAAATATTTACAGAAATTTTCGTG
+ATTCTACAATAATATTTTTGTAATTTTCTCAATTTTCAAAAAATTGCCAA
+TTAATTTTGAAGTTTCGAATGAAGCAATTGCCGAAGTTGCCGACTCCCGG
+AAATTTCGAAAACCGGCAATTGCCGAAATTGCCCTTTGCCGGAAATTTCG
+AAAACCGGCAATTGCCGAAATTGCCCATTGCCGGAAATTTCGAAAACCGG
+CAATTGCCGAAGTTGCCGACTCCCGGAAATTTTGAAAACCGGCAATTGCC
+GAAATTGCCGACTCCCGGAAATTTTGAAAACCGGCAATTGCCGAAGTTGC
+CGACTCCCGGAAATTTTGAAAACCGGCAATTGCCGAAATTGCCGATTGCC
+GGAAATTTCGAAAACCGGCAATTGCCGAAATTGCCGCTTGCCGGAAATTT
+CGAAAACCGGCAATTGCCGAAATTGCCGATTGCCGGAAATTTTGAAAACC
+GGCAATTGCCGAAATTGCCCATTGCCGGAAATTTCGAAAACCGGCAATTG
+CCGAAATTGCCGCTTGCCGGAAATTTTGAAAACCGGCAATTGCCGAAACT
+GCCCTTTGCCGGAAATTTCGAAAACCGGCAATTGCCGAAGTTGCCGACTC
+CCGGAAATTTCGAAAACCGGCAATTGCCAAAATTGCCGATTGCCGGAAAT
+TTTGAAAACCGGCCACTGCCGAAATTGCCGACTCCCGGAAATTTCGAAAA
+CCGGCCACTGCCGAAATTGCCGACTCCCGGAAATTTCGAAAACCGGCAAT
+TGCCGAAATTGTCGATTGCCGGAAATTTCCGATCCCTGAGTTTAGCCTTT
+TTCAGCAAATCAAACAGTTTATGATTATTTTTTCAAAAATTGTTCTGCAG
+TGCTCTTGCATCACTATTGTGGCCCTCCTTTAAATACAGTACTTTCTACA
+GTACCACTACATCAATGATCCTTCCAGTAATGCCAACACATTGTACCACT
+ACAGTAATCCTACAGTACCCTATACAGTACCGTCGCAATACAATTACCGT
+AACACTATGGAAATCTTACAATAGACTACAGTATACAAAAACTACAGTAA
+CCCCCTTGAAGTTAGTGTAAAACTTGCAAATGTTCAACTCTTTTTTCTGA
+TTTTTTTTTGTTAAGTTCAGAAATTGTAGAGTGTTTTTGGCTTCTGCTCA
+GATTTTCAGAAATTTTCGTGATTCTATAGTAGTCTTTTTGTAATTTTCTC
+AATTTTCAGAAGTCTGCAAATTCAATTTGAAATTTCGAATAGCTTTAAAA
+AACTCAAACAGTTGGCACAAATTTTCGTAGATTCATGTAGAATTTCAGCC
+TTTTTCAGCAAATCAAACAGTTTTTTATTTTTTTTTGTATTTTTTCAGAA
+ATTGTTCTCACCCTCCAAAGTACTATCACGTCCTAACAGTAATATTAGCC
+TACCGTATCACTACAGTAATCCTCCAGTACTTCTGTGCATGCTACAGTAC
+CCTTGCATCACCATAGTGGTGATCCTTTAAACCTACAGTACTTCTACAGT
+AGCACTACAGTACCACTTCAACAGAATCTTTCCAGTAATATCAGCGTATC
+GTACCACTACCGTAATCCTACAGTACCGCCACAATACTATTACCGTAACA
+CTATGAAAATCTTACAATACACTACAGTATACAGAAACTACAGTAACCCC
+CTTGAAGTTGGTGTAAAACTTGCAAATGTCTACCGTAATCCTACAGTACC
+CCAATACAGTACCGCCGCAATACAGTTGGCATAACACTATGAAATCTTAC
+AGTACACTACAGTATGCAAAAACTACAGTAACCCCCTTGAAGTTGGTGTA
+AAACTTGCAAATGTTCAACTTTCTACAAATTTGCCATTAACTTGTAAGTT
+GGGGGAGCGCATCGAAGTGTATACATATATGTACATGCCAACCAATTATT
+TTCTCAAACAATTTATTAATAGTCGAAGACACCTGAAGCAACGATTAGGA
+GGAAGAAGAGGAAGGAGAGATTGGCAGAAGAAGAAGAAGAAGACGAATTA
+GTTGAAGAATCTGTTGAAACGGAAGACGTTGTTTGTGATGTCTCTAGCCG
+TGCGACAGCTTCCCGTTTCAGACGGAACGATGTTCGCACGGCGATCGGTG
+GCGAGATGTCGGACACGTCGATTGTCGACGAGAAGGGATCAGAGACGGTT
+GAAGAATGCTGAGGAGGAGGATTATGTCGACGTTCCCGTCCACGACACGC
+GGCCTGGGTACACGTGACACAGACGTGAAGGTTACAGAAGATGTTCACCT
+CGTTGCTGGAATAATAGTCGTTGAGAGGTGGGTGGTGAACATGAACAAAG
+AACTTAAGAGGCTTACCTCGTTGGGAATGCCCAGGCCTTTATGTGGTTGT
+AGAAGATGGTCTTACCATTGCGTCGAGTCACTTCAAAGTCTCCCCACACC
+TGGAACAATTTTCTATGGAAGTCTCAAATAATATGCAGTTGGTCGATGCA
+CCATGATGAATTTTGTGCCAAACATGGTGCATCGACGCTAAATAATTTTC
+TTTTGAAATTTAAAGATGTTTTGCTAGACTTTCCCTAAACATCTTTTTAG
+TTTTCCAATGTTCTCTAATATCATCATGGTGCATCGAGAAAAAATGTTAT
+AGGAGGAGTAAAGAAATTTGAGACTTTACTTTTTTAGACCAAAAATGACC
+CAAAACTACCGAATTGTTTAGTAAGACGTTTTGAAAATTTTTCAAAACAA
+AGTTATGGCGGTTCAAAGTTCTGGAAAATAGCATATTTTCAGCTAAAATC
+TAATGTTTTGGGGGCTGGGGGAGGAATAAAAATGTAATTTTTTTTGTGCC
+CCACTGCCCGAAAATGCACTTTAATCGACGAATAAACGGCTTATAAAGGG
+CCACAATATTTATAAAAGAGTGATATTATAGTTATAAATAAAAATTGAGT
+TCCCGACCGAGAAAAAAATTGGCGAAAATTTTGATTTTAGCTGAAAATGG
+GACTTTTTTTCCAAAACTTTGAGCGGCCATAACTCTTTTTTGAGAATTTT
+TCAAAACGTCTCATTTAGAAATTCGGTAGTTTTGGGTCATTTTTGATCTA
+AAAAAGTAAAGTCTCAGATTTTGATACTTTCTCGATGCACCATGATGAAG
+AGAAAAAAAGAGAAAATTTAGAAAAAAAAAAAAAGAACCCTTCCGATGTT
+TTGGGAAAGTTTAGCAAAACAATAGATTTGTAAAAAATTCAATTTCATTA
+GGTTCCTATTAAATTCTCAATTTTTATCAATGCACCATACATTTTCAGCG
+TGAAATTTTGTAAAATGCACAGGAATGAAAATTGATCAGGTGTGTATAAA
+ATAAGAAATTGAAGCATTTTGTTTTTTTTTTTGTCGATACACCATGATGA
+ATTTCACGTCAAACATGGTGCATCCTGGAAAGGAGAGAGTTTTAAAAATG
+TATCATTTTTTTCTCGATGCACCATGAAGATTTATATTAGTAGAACTTAA
+ACCGCACTTAGCATAAGTGGCATAAAAATAAAGGTGGAGTAGCGCCAGTG
+GGGATTTTGTCTAAATACACTTATTATGATCCAAAACGATCGAATATCTT
+AATGAAACACTCCAAAATATTTAAGATTTTTCAAAATTTCCGGTCAAAGT
+TTTGGCAAATTGCCAAAATATTGAAAAAAAATATGAGCTTTTGAGGAAAT
+CCAAAGCAATGTCGCGTGTTTCGACCCACACAATGTTTTTATACAATGTA
+GAAAAAAATTTTTTTTTGGTCGACTTTTAAAATTATGAGTGGCAAAAACT
+GAGTAATTGCCAATTTGACAGTAAATAAAAAATTTTCAAAAACATTTTGA
+AAAGTTTTATTATGATATTCGATTATTCTGGCACCATTTGAGTGGTTTGT
+AGTAATTTCCCCACTGGCGCTACTCCACCTTTAAAATTAAAAAAAAAATC
+ATAATGGGTATTTAATATCAATGAAAATTATCGATTTTTCCAAATGTATC
+AAAATGAGTGTTCAGCGCGAAATTTTGTGCAGGACTTTTTCTTTCAATAA
+TATATCCCGAATGATGCATTAGTTATGGGCTACACGATTTTTAGAAAAGC
+ACCTGGCCATGCTTAAAGGTGGAGAACCGAAATTTGATACTCTGTCTTTT
+TAGATCCAAAACGGTCCAAGACTACCAATATTCGTATTAACCTGTTCTGA
+AAAATTTTCAAAAAAAAAAGTTATGGCCGTTCAAAGTTTTGGAAAAATGG
+TCGATTTTTAGCTAAAATCTCAAATTTTGGCAACTTTTCAATGTCACAGC
+TGGAGCTTAATTTTAGAAACAACACGTGATAAATTGCAAAAACATGCATA
+AAAATATGTTCCAACCGCTCCGACACTAAAAAGGTGCCAAAATTTGAGAT
+TTTAGCTAAAAATCGACCATTTTTCCAAAACTTTGAGAGGTCATAATAAC
+TTTTTTTTTTGAAAAATTTTCAGAACGTCTTAATACGAAATTTGGTAGTT
+TTTGGACCATTTTGGGTCTAAAAAGGCAAAGTATCAAATTTTGGTACTCC
+ACTCACTATCGAAGCAGAGCCCCAAAAGTTTGACCGACCCAATTTTGTAA
+GTTTCTTCGATGCACCATGATGATTTTGAGCAAAATGTTAGTTTTTTTTT
+TTGAAAAACTGGTGGCAGGACCCAGTTTTCGGCAGTTTTAAATGTCGATG
+CACTATGTTTTTTTTAATGAAACCGTACCTCCCCAGAAGTCTGCAAAGAG
+CATCCGTGTGAGTCCGACAGTGGTAGCTCGGATATCCCGTCATTCGCCCA
+ACACCTTCCGATTCGTCCATTCTGATCATCGCTCATTTCAACTGTGTACG
+TCTACAATTTACAAATAGTTTCTTTTGATTTATGGAGTTCCTGACTTACA
+ACTCTATCACCAACTGCTAACGGACGTTGTAGCTGCTTTGAATCCAAACT
+GTCGCCGTCTAGAACACGAACTCGGTAGTCGACTGTCTGAAACATTATAT
+GGGTCTCGCAGCGATAATTTTGAAGCCTTACCTTATTATCCGATAGGCTG
+CTTGCTGTGGTGGCATCCGAGTTGATAGTGATTCCACCAAATGATACGGT
+CACCTGAGATTCTTTAGGAACAGGGGCAGCAGGTATACAGGTCAGAAGGA
+ATCGTTTGTCGGTTTCTGCATTGAATCTTAAAAAAAAACGATGAGGAAGT
+TATTTTTTATTTTTGTCTATTTTTGTTCGTATATGGTTTTTTAGGTACCA
+TGGAATAAAAAAAATGCTCCTAAAAAAATTAGTTTCAATAACAAATATTA
+CTGGTACAGAGAGTGTAGATAGTTAGAGAGTGACTGACATCCGGGACCCA
+ATGGGGCGGGGCGCGCGGAAGAGACGATTCGTGTCGATTTACGAAATGAT
+GACAACGAGGAAAATTTCGTAAATCGACACAAATCGTCTCTTCCGCGCGC
+CCCGCCCCATTGGGTCCCGGATGTCTGTCACTCTCTAACTATCTACACTC
+TCTGTACCGGTAATACCATAATATGATCATCATTCTACATTAGAAAAAAA
+TCGATCTGAAATCACAGATTTTTGGCCTCCCTCATAAATTGAAATGGAAG
+AGGTTGCCAAACTAGGCCATTTTGGCTCGGCCATATCTGGGGTAGATTTA
+CGGCGCGTTGCGTGTCGCGTCGCGGCTCGATTTTAGTTGTAAAACTAAAT
+GTAGTTGGCCGTGTGGAGTACACGACTTTCCCACGCGTTGCCCGACGGGC
+GATTGCCAATGGAGCGCGAGAATCTCAATGAGGAAGGCCATGGCGCGCCA
+GAACCCCATGATTTTTAGGGTATTTCGAGGTTGGCAAATATTCTGGAATC
+TTTTTGCAAAATGTTTTTTTTTTTTTGAAAAAAAAATTCCAAAAAATATC
+CTGATCGATGAAAATTGTTGGGTGAAAAAAGTTGCAGATTTTAGGAGAAA
+TTTGAGAAATTAGAAAAATTAGAAATTAGGAGAAATCAGAAAATTTCCAA
+ACTGCTTTCAGAATACTTGTATATATTGAAATAGCCTAAAAATCATGAAA
+TTTTTCAAAAATCTCTAAACTAGCCTCCAAATTTGGTAGTAAAAATTCAC
+TGGCAGCAACTTCAGAGCGAGATTTTTCTAGTTTAAAGTGCTCGTATGTC
+GCTGAATTTTTTGTAGGTACCTATTTGAAAGCTCTTTTTTCAAAATTCAA
+AAATTTAATTTTCAAGTTTAAATTTTGAGTAGCGCCAGTGGGGGATTTTG
+TCTAAATACACTTATTATGATCCAAAACTACCTGAGTAATTGCCACTTTT
+TGACAGTAAATAAAACATTTACAAAAAAAAAAAGTTTTATTATGATATTC
+GGTCACTTTGGGACCAAATGAATGGTTTTTCATAATTTCCCCACTGGCGC
+TACTCCACCTTTAAAACTGAGCGGAAATACTTTCCTTGTGAGCATAGCGG
+CAAAAAACCTAGTACCACATGGCAAAAAAAAACCCACTCATTGTTAGCCA
+TGACAACTTCGATCTCATTCTCCAAATTGCCTTCTCCGTTCTCCTTGGTC
+GAGCAGCCAGTCAGCGGAATCTAAGCAAATAATGCCCAAAAATTCAATAC
+ATTCAATAGGCAAACCTTCAACTGATATTTGGTGTCCGATTGAAGCGTGC
+CATTTGCATAGATACACTTTGGATGGCCCGCGCGACTTTGTATCGTGCCA
+CGGAAGTTTTCGTCAAACTTGATTTTCAATAGGAAATCTGTCTGCAATAT
+TGAAGACGTTTTTTTCCTTTTGGGTGGTGACCTTCAAGGTTTTGGCCTGG
+GTTTTTAATCTTCCATTAAATGCCCTTCAAATTCGCTTTTTCGAGAGTTT
+AAGAGAGTTTCTAGGCCGAGGAACTTCTTGCAGCCAAATTTCTAAACTAT
+TGTGTTTTTGCCAAAAACAATGAAACATTTTAGGTCATTTGTGACGTCAT
+ATTTTTTCCATGCAACTTTTTATTGGCTCCACACATCTTCCAAAAAGCCT
+AAGCCTGAGCCTAATCCAATGTCTAAGCTTAAGCCTAAGGTTCAGCCTAA
+GCGTACGCCTAAGCCCAAACCAAAGCCTAAGCCTAAGCCTAAGCTCAAGC
+CTAAGCCTAAGCCTAAAAAAAACCGGAAAATCCTAAGCCTAAATAGCGTC
+AGTAGCAAGCTAACGCTCGCCACTGACGCCAAACCTAAGTCTCGGCTTAA
+GCCAAAGCCTAAGCCTAAGCCTAAACCCATGATTAAGCCCAATCCTAAGC
+CTACGCCTAAGCTTGAACCTAAGCCTAAGCCTAAGCCTAAGCCTAAACCC
+AAGCCTAAAATTTCTAGGCCACCACTAATATTTTCAAAACTCGATTCTCA
+AATACTTCATTTTTTCAGGATATGAAAGTAGGACAGAAATGGGCAGGGTA
+TATGGTATGGAGCAAATATCACAAGATGGCAGAAACATAGATACGGGGTG
+GGAGTGTTGGACTAGGTGACTTTTCTAGGCCATCCCTACCTTATCACACG
+CAATAGAAGTGTCCACAATGGCCACCGATCGAATCAGCGGTGGCAGCACC
+ACAACCACCGACCAAATGATCCAGTGCAGAATCATAAATTTGTGGAGGGA
+AAAATCGATAACAGTAGTGAGGGTAATAGTAGTAATAATACAAATATATA
+TGGAAAAATGAATACAAAAAGATGTGTGCGCTGGTTGGGGTGGTGGCGTA
+AGAATACAGGTGGGTGGGGGGTATAATTGGAGCGTGGCCGAGGAGGAGAA
+TCGCAAAAAAAAGAAGGAAAGAAAGAGGATAGTAATGACATGTTACGGTA
+GAAGGACAACTACCTAATTATATGAAAGAGGGGGGGGGGGCGACGAGAAG
+AGGAAAAAGTCTTACGCAATTTGCTACTCGACTTTCAATTTCTGCTAGAA
+ATCGAAAAAAAAATAGGAAACAAATTCCGACTCTATTCGATATCATCACT
+TCCGGGGCACGGCACAGGTCGGATCAGATTCAACGACGTCTCGCGATCCC
+GACCCTCTGATCTTACGGCCATCCCATTGTTCACATGATAGTCGATGAGC
+TCGGAGATGTTGCTGAACGTGCGATCGCGGGTTCGGACTCTCTGGAATTT
+TGAGAGGTTTGAAGGTTTGGCGGGGGGGGGGGGGGAGGGTCTTACGTTGT
+GATTGTCCAGTAGGATGAGATGTTTGTGCTCGTTTTCAGCGGTTCGGCCA
+CTCAGCACGTACTTGCCGGGCGTGTGGTCGCTTTGTCTGCAAGGAACTGG
+ACAAGTTTGAGCGGCCGACAGCTTGCGGGTCTTTTTTTAGAGAAGGGGGA
+CTGTGAGGTGTCCGCTGCTTCAGACAATCTTAGCATCATGCAAACCTTGC
+ATCTTTTGTATTTCAGGAAAAAAAACGCAGAATTTTTTTTGAACAAAAAT
+TTCAGCCTAAAACAAAAATCTAAAAAAATTTTGGGAGGATGAACTTATTA
+TACCAAATTTTTCCCTGGTCTTTCAAGAATTATTTAAAGTCCCGTGGCTT
+CTGAACATATTATCAAACAAATTACAGATATGAAATGTGACTGAAGCTTT
+AAGTCAGAAATATATAAAAAAAGGATTTTTCATACTATTTTTTCAGTCAA
+ATTTGATTTTTTTAGACTTTCAGATTTTTCTACGAAGTCTGTTAAAATAG
+GCTTATATTAAAAAGCTATCCGATTTACTATTAGTAAAAAATTATAGCGA
+CCGACATCTCGCAGGTTGTTAAAGAAAGGTGCATTGACCGGCTCACGCAA
+CTTTGGCAGTTTATATCTCGGCTGGTTTTGGTTTTATTTAAAAAATTTCA
+ATTGACGAAATATTTATCACTTTTTCTACTAAAAGTTTGCAGTTGAACAC
+TTTTTGCTAGCAGCGATATTAACCGAGATATTAGCGGAAAAAGTTACATG
+AGAAACATGGTGCATCGACAAGAAATATCTCACAAAACTTTGGCAGGTTA
+TATCTCGGCTGGTTGTGGTTTTATTAAAAAATTGTTAATTAACAAAATGT
+TTATCCTTTTTTCTACTACAACTTTGCAGTTCAACACTTTTTGCTAGCAG
+CGATATAAACTGAGATATGATTGGAAAAAGTTACATGAGAAACATGGTGC
+ATCGACAAGAAATATCTCACAAAACTTTGGCAGGTTATATCTCGGCTGGT
+TGTGGTTTTATTGAAAAATTGTTAATTGACAAAATATTTATCCTTTTTTC
+TTCTACAACTTTGCAGATGAACACTTTTTGCTAGCAGCGATATAAACCGA
+GATATGATTGGAAAAAGTTACATGGAAGACATGATGCATTGATCAGCTAT
+CATAGCTCATATTTTACTTATCTCAGGTTTTACCAAAAAATTGCCAATTA
+TTAAAACATTAGCCTTTTTCTTCGAAAATCAAATTTTGCCCGAATTGCCG
+AAAATATAGATTTGATATTTTTTTGTAGATTTAGGAGCCTAAACATTTTT
+TAATTTTTTAAGTATTGACCGTTTGCTTTTAAAAATGACTAATCGAATAC
+TGAAAACACAGTTAACTTTTTTTTCAATTTTCGAATTATAATTAGGTTTG
+AAAATTGCCGAAAATGTCGGCATTCAGTTGGAATTTTGGCAATTGCCGAA
+AATTTCCGATTCCCACGCGCCCCTGGTGTGAACCTAGTGAGCATGAAGCC
+AAACGTTTTAGAAATTCAGCAAAATTCTAGCTTTTTTCTATAAAAAATCT
+AAAAAACCTTACCGAACCAAAAAATCGCCTTCCGTCTTCAACAAAGCCTG
+TGCATCCTCTCTGGATAAATTTCCATGATACCAAACTTTCCCCACAACAT
+CCTCAGTTACAGTAGGTGCTCGGCAATTCGACACAAATGACTGTCGATGC
+AGGGAACTTCGATGTCTCATCGGCGGCGCCGGCACCGTAAATCCATCGTT
+AGAAGTTGAAGCATTCGCCTGTGCATCAAAAGTGTTCACATTGATCGCAG
+TGGTAAGGACGTCGATGAGCTTGTGCACATCCTCGATGAACACCACGTGG
+CATCGACGATCCGTTCCATCCTTGTTTTTTGCAATGTAGCCGAACATTAG
+CTCCGTGTCCGTACCCTTTTGGCCTTGGGCTCCGAATGAGAAGAATGAGA
+AGGGATGACGTTGAATTAGACGACTTTGTTTTATGATTTTGATCATTTTC
+GAGGAAATGTTGATGTCTACGGGGAAGTTTTCTTTTTTCACTTCACCGAT
+TACCTGAAAATAAGGATGGTTTACCTGGGCTTTTTCATCGACCCGTGAAG
+TGTCGGCTGCAATAATTTTAGTCGAAATTAGTGATAATAACTTTTCTATG
+AATAGCGGCTGACATCATTTAGCGCGATTTTTGATCGACCTGTAAGATGT
+CGGTTGCTTTAGTACATTCTATAGTGGCAGGCTTTTGGCTGAATTTTACT
+GGATATATAAGCTATCAAAATTTGAGCATGTCGATGCACCATGTAATTAT
+CTCAGTTTATTTCGCTGCTATCAAAAAGTGTTAAAATGCAAAGTTGTAGT
+AGAAAAAACGATAAATATTTTGTCAATTGACACTTTTTCAAAAAAAAACC
+AAAACCAGCAGAGATATAAGTAGTCAAAGTTGAGTCAGATATTTCCAGTC
+GATGCACCATGTAACCTTTCTCTAATAACCTGTGAGATGTCGGTTGCTAT
+AATTTTTTAGTCATTAATTTGGACAGCTTGTTAATTTGAAATAATTCTTG
+ATGATATCGTAGCGCGGCCGACATTTCACGGGTCCTTTTTTTTAAACATT
+TTGCAAAGCTGGTCATGCATTTTTGGTAACACTTAATATCAAATTAATGA
+GAAAATGTTTTGTAAATTTTTACCATTAGCCATGCCCAGAAAATGGCAAG
+TTTTTTATTTTATTTTCTTTTGTTTTTTTAATTCACAAAAAAAAACTCAC
+CCTACTAACAACTGGATTGATTTCTCGAGCCGCAGTCACGCCAACAGTAG
+CTGCAACGTGTTGTATACATTCTCTGAAAATTGAACAGTTACTTTATTAC
+GTAGATTTTTTATATATTTGAGCTTGCAGATGTTACCTGCCTTCATGCCT
+GCCTACCGCCTGATTTCTAAATTTTTGAATAAGATTTTTTTTTGATTTTA
+AGCCATAAGAAAAACTAACGAAACAACTTGAACTCTCATCTCGGAAACCA
+TCACGTTAATTGACTCGACTACTGGAACACTTCCGAGGTACTGAAAGACA
+ATTTTATATTTTCGGGGAAAAAACTAATAAAAAACTCACAGTAGCCGACA
+GAGAAACCCCGCTGCTCCGCAGCTCCTCTGCAAATGAGGGCTCCACGTTG
+AGCATCGCCGCAAGTTGATTTTTCGACGGAATTTTTGATTATTTTTAGAA
+AAAATCTAACTCGAAATTCGTTACAACCGAAATTTTGCAAGATTGAGTGA
+ATGAGGAATGACCGGGAGAGAAACGGAGACGCAGGCGGTGAGCGGAGTGG
+GAGAGAGAGCGCGCGAGACGGAGAGGCGCAGGCAGTGGTAGGGAGGAGAC
+AGGGAAAGATTAGATTGGTGTTGACTGGGTGAGTCAGCATTCTAATAAGT
+TAAGTTGACTCATAACTTTGTTTTTTGATCAGAGGGGGGGGGGGGGGGCC
+GTGGCCTAGAAATATCATTGCCTACTTATTACGTCACTAATGGTCTAGGA
+AACCTTGATAGCTTTTTTGGAGAAGATATGACGTCATTGGTGGACTAGAA
+ATCTTATTTTAGTTCTGGAAGAGAAATATTTTGACCGTGGAAGACAAATT
+AATGATGTGACCGGTGGCCTAGAAGTTTCAAATTATACCTGGGGAAATAA
+ATGACGCCACTGGTGGCCTAGAAAACTTAAACTATGCCTGAAGACGTCAC
+CGGTGACCTAGAAATTTAATTCTGGCGACGTCATAGAAATTTGAATTTTG
+ATGAGAAATATAATTTTATTGGTTTTCTGAAAATTGAATTTTATTGATTT
+TTTGGCAACCGGGAAATTGGAAAATTTAATAAATTGAACAAATGCAATAA
+AATAAGCAGTTTTTCAACAGTCATTACTTTTTTCCGTGAACCGTTTTGAT
+TTTAATTTGTAAATCTAGGTCGGAAAAGTCACACACACCGAGGAGCTAGG
+CTTCCCTCATCCTCCCTGGATCAGTCGGTAACTGCTTCGACTGGGGAGTG
+GGAGTGGGAGGGGTGGGATGAGTTCAATTCTTCTGGAATTCCATAATTTT
+TATTTTTGTTTTTTTGCGCCTACATATACCTGTGAAAATTGGAACTCGAC
+ACAAAAACCTCTCTAGCGCGGCTTAAATTTACTTCAATTCTTCCGGAATT
+CCATAATTTTTATTTTTGTTTTTTTGCGCCTACATATACCTGTGAAAATT
+GGAACTCGACACAAAAACCTCTCTAGCGCGGCTTAAATTTACTTCAATTC
+TTCCGGAATTCCATAATTTTTATTTTTGTTTTTTTGCGCCTACATATACC
+TGTGAAAATTGGAACTCGACACAAAAACCTCTCTAGCGCGGCTTAAATTT
+ACTTTCCTGTCCCAAAAACTCATCTATAATATTTTTAAAAAATCTAGAAT
+CCAAATCTATCAGATTTTTTTGAATTTTTGATTTTTTTCACATCGAGATT
+CGGAATCAGCGGAAAATTTGGAGTCAATTAAAAATATTTTCCAGATTTCG
+ATACTCCACATTTAAAGGAGATCACCTGAAACGCCAGAATATGATACTTC
+ATACTCTCCATCTTCTCGCTTTTGAAAATAATCAAAAAAAATAGTCGCCG
+TATTTATTGATATAGAAAAAATACCAACAAAATTGTAACTATTGATTAGC
+CATACAGGGTCTTTAAAGTCAACATTCATAGTGGGAGCTGGAAATAAAAA
+TATATAATAACTTGTTAAAAGAATTTATTGTGGAGTTATAACACCTATAG
+ACAATTAAAATCACCTGCTGCCTAAAGAGTATTTACCAGAAGCAAAGGTT
+TTCTGAATTTAGTGGAGTTTGTCCATTTACTTTTTTGCATGTTATTGAAT
+TGAAATGATACATAGTGAAACTAGAGGTAAAATTATTTACTAGGTTTAGG
+CTTAGGCTCAGGATTAGGCTTAAGCTTAGGCTTAGTTTTAGGTTTAAGCT
+TAGGCTTAGAATTACCGATAACTGATAACTTTTGCAAATTTAGTTTCTGT
+AATATCGGCAATAGCCAAAATTGCCGGAAATTTCTGCGATTCGAATAAAT
+AAATTGAAATAAAAATTAGTTCCTAAGATACATGTTATCTTTTTGCAGGA
+AAGTAGTAAACTCATGAAATGAGAAATTGCGATGAGGAAGGAAACATTCC
+TATGGTTCCTTAGACAATTTCTCACCTTACATTAGTATATAATATATAAA
+TGATGAATTTGACTTTTTGAAATTCTCTTCAATAAATACATTTAGTTGTT
+TTTTTTTTAATGAGTAAAGTTGCAGAGTGTGGAATTTGCTATGAGGAATA
+TGGTGAATATTGTTGGAAATTTTTCTGAAAGTTTTCATTTTTTTTGGAAA
+TTTAGAGAGTTGGGTGTAATTACTGAAAATTATGTTTTAAAAAAATTATT
+TTAATGATTTTTCAAATTTTACAAAAAACTCATTTTTAAATCATTAGAGG
+TGAAGTAGCGCCAGTGGGAAGATTGTTAAGATCCACTCCTTTAATCCGAA
+AAGTACCGAATATCATAATAAAACTTTTCAAAAGTTTTTAGAAACTTTTT
+TATTTACTGTCAAAAAGTGACAACCACTCAGTTTTTGCCACTCATAATTT
+TGGAAGTCGACCAAAAAAAAAATTTGTTTTCCTACATTTTTTATACTTCA
+ATTTTGTTTTAATTATTTGTATTGAAAAATTGTAGGGGTCGAAACATGCG
+ACAATCCTGTCAGTTTTCAAAAATCTCTACTTACAAAATATAGGACACGC
+TCCAAAAATGGATGTTTTTACAGACAACGCCATCCGAATCCCTTGCATCG
+GCACATGCGGTCATACGTTATGTGACAGTTGTCGTGAGAAAATTAGAGAT
+AAAAAATGTCCTCAGTGTAATCAGAAAGGCGCATTTGTTGTGAAAAATGT
+GAATAAACAATTTTGGGATTTAATTGTTTTTTCGCAATTTTTAAAACCCC
+AGGAAGTGGAAGTTGAGGAGACTGAAGAGGTTGGTTAGAACTTTTTTTTT
+GGATTTTTCGGTATTTCCGGGAGGTTATCCTTTGGGCCTAAAACTAGGCC
+TAAGAGTAGGCCTAAGCCTAAGCCTAAAACTAAGCCTTAGCCTAAAACTA
+AGCATGAGCCTGAGCCTAAGCCTAAGTCAAGCCTAAGCCTAAGTCTGCTG
+CTATCAAAAAGTGTTAAAATGCAAAGTTGTAGTAGAAAAAACGATAAATA
+TTTTGTCAATTGACACTTTTTCAAAAAAAAACCAAAACCAGCAGAGATAT
+AAGTAGTCAAAGTTGAGTCAGATATTTCCGGTCGATGCACCATGTAACCT
+TTCTCTAACAACCTGTGAGATGTCGGTTGCTATAATTTTTTAGTCATTAA
+TTTGGACAGCTTGTTAATTTGAAATAATTCTTGAAGATATCGTAGCGCGG
+CCGACATTTCACGGGTCCTTTTTTTTTAACATTTTGCAAAGCTGGTCATG
+CATTTTTGGTAACACTTAATATCAAATTAATGAGAAAATGTTTTGTAAAT
+TTTTACCATTAGCCATGCCCAGAAAATGGCAAGTTTTTTATTTTATTTTC
+TTTTGTTTTTTTAATTCACAAAAAAAAACTCACCCTACTAACAACTGGAT
+TGATTTCTCGAGCCGCAGTCACGCCAACAGTAGCTGCAACGTGTTGTATA
+CATTCTCTGAAAATTGAACAGTTACTTTATTACGTAGATTTTTTATATAT
+TTGAGCTTGCGATTGTGTAATCAAAAATAAACATTTGAAGCATGATACGA
+AATATTTGAACGATTTTTTTTCGGAAAATCAATAAATGAAAATGGAGTTT
+TTTTTTTGGATTTTAGCAAACTTCCCAAATGACGGAAAGATCATATGAAG
+CGATTATTTTTTCTTTTATAAACCTGTTCAGGATTTGCATTATTATGAGA
+AAATCCTAGGCCAATTAGGCTAGCATGTACGGAAGTATTTTTTAAAAATT
+TATAAAAGTAATGAAAAGCTGATATTTTCAAAATTCCAGAATGACGGAAA
+AATCATATGAAATGCTTTTTTTTTCTTTTTTAAACCTATTTAGAATTGTC
+AAAACTACCAGAAAATACTAAACAAAATAGCTTAGCTTGACCGGAAATAT
+TTTTAAAAAATTGATAAAAATAATGAAAAGCTGATATTTTCAAAATTCCA
+GAATGACGGAAAAATCATATGAAGCGATTCTTTTTTCTTTTATAAACCTC
+TTTAGAATTGTCAAAACTACCAGAAAATACTAAACAAAGTAGGTTAGCTT
+AACCGGAAGTAATTTTTACAAATTGATAAAAATAATAAAAAGATGATTTT
+TTCAAAATTCCAAAATGACTGAAAAATCATATGAAGCGATTCGTTTTTCT
+TTCATAAAATAGTTTAGAATTGGAATAATGATCAGAAAATACTAAACAAA
+GTAGGTTAGCTTGACCGGAAGTATTTTTAAAAAATTGATTAAAAAAACTG
+ATTTTTAAAAAATTCCAGAATGACGGAAAAATCATATGAAGCGATTCTTT
+TTTCTTTTATAAAGTAGTTCAGAATTAGCATTATTATGAGAAAATCCTAG
+GCGAATAAGGCTAGCATGTACGAAAGTATTATTTAAAAATTTATAAAAGT
+AATGAAAAGCTGATTTTTTAAAAATTCCAGAATGACGGAAAAATCATATG
+AAGCGATTCTTTTTTCTTTTATAAACCTGTTCAGAATTGTCAAAACTATT
+AGAAAATACTGAACAAAATAGGTTAGTCCTAGGAAAGACTAGTTAGGAAA
+GAATTCTTAAAATAGGAAGTTGAACAGAAAATCTGGAAGATCTGAAATCT
+GGAAAAAGGAACTCTCAAAAATTCAAATTTTGATTTTAGGAATATATGGC
+TGTGTAGTCTTCATAGACAATCAAAATAAATTATTTTAATTTTCAACCAT
+CTTTATGCACGGGCTTCTGTCCTTCCTCATTGAATTTTTCGCGCTCCATT
+GACAATCGCCTGCCGGACAACGCGTGGGAAAGTCGTGTACTGCACACGGA
+CAAATACATTTAGTTTTACAACTGAAATCGAGCCGCGACGCGACACGCAA
+CGCGCCGTAAATCTACCCCAGATAAAGCCGAGCGAAATGACCTAGTTCGG
+CAAACTCTTCCATTTCAATTTATGAGGAAAGCCAGAAACCCGTTTTTATG
+TAAAAGTTCATACTGTGCAGTTAATTTAAACAAATCAAAATTTGGAAAAT
+GATTTTTGGCTTTGTGCAAACTGTAGCGTTTTAGGCGTTAAAAATCTGCC
+AATGAATAAAAAATTTCTTATAAAATTTTTAAAAAAACAGTTATTTGCCC
+ATTCCGTTTTTCAACATTTATCAATTACGGTTCCAGTGATCAAATGCTTA
+CACGGAAGTCACTGATGACGTTGACTCCATGTTTGGTTGCGATGTGAAAA
+AGGTCGTTTTTTGCCCAAATCGAGAAAGGTCACACACACACATAGACATA
+CACAAAACCTTATATAATTTGTAAGATATTTTGTTTGATTCGAGAAAAAA
+AAGAGAACAGGTATTCCTGCGGCGTCGTTTTTCTAAACGGCAGGAAAAAT
+TGAGAGAAAGAAAGAGAAAGAAAAAAGATGGAAAAAAACAGTTTAAATAT
+AATTATTAGGTTTAATTATTAGGGGTGCACCATATTGTCGTAGGGGCCCT
+TCTCCAAAGTTTTAAGTTTATCGATAGAGCGTGAATACATAAAGAGAGAA
+ATTTGACCTGCAAAAAAAATATATGGTTGGTTCCCATGCCATAAAAAATC
+CATGCAACAAATGAAAACAACACCTGCCAAGTGTCCTCCGCCAGTCTAAC
+CAAGTTTTTCCCTCCAAATGTTCCGTGACATTGTTGTTTAAGGCTTTGTA
+CTTTCCGCAGCCGTCTTATTCTTCCCGAAGTGTTCTCCCTAGATAATCGG
+GTTTTTTTGTTGAATCGGCTGGGGGTAATGATCGGAGAAGATATATATGA
+AATAAATGAATAAAAAAGGAACACCTTTTGGAGAGGCAATGAAAAAGCAA
+GCTATGCAAAGTATTGATCCGTTGTTATGAATGGGCTTGCTTAGGCTTAG
+GTTTTTTTTAGGTTTAGGCTTAGGCTTAGGCTTAGGCTTAAGCTTAGGCT
+TAGGCTTAGGCTTAGGCTTAGGCTCAGGTTTAGGCTTAGGCTTAGGCTTA
+GGCTAAATCTAGGCTTTGGCTTAGGCTCAGGCTTGTGCTTAGGCTTAGAC
+TTAGGCTTAAGCGTAGGCTTAGGCTTAGGTTAGGCTTAAGCTTAGACTTA
+GACTTAGACTTAGGCTTAGGCTTAGGCTTAGGCTTAGGTTTAGGCTTAAG
+CATATACCTAGGCTTAGCCTTAGGCTTAGTCTTAGGCTTAGGCATATGTT
+TAGGCTTATGCTTTGGCTTAGGCTTAGACCGTGTGTATATCCGAATGTGT
+GTTTTATTATGTTCCTGATTCTGAAATCATTTGTTAGTTTAATATCTACA
+AACATTCCAAACAGTCTGTATGTGCTGCCAGGTGGCATTTCCTTAATCAT
+CTCAAATATATTTGGTTTCATTTCCCCCCATCGCAAAATCCCTTTCTTTA
+CCTGTCATTTCGCCTTTACGTTCAACTTATTTGATTTTGTTGTTTTCAAG
+TGATAATCACGATTAAACAACGAATGAAAAAAATAGGTATGGAATTACTA
+CGGTATTCTTTTTTGCCTATCCTTCTTTCTCTCATTTTCCTTTTGTCTTC
+TAACAAGTTCTGCACTTTTGAGGTACATTTCTTCTCCGATTTGATCAGTC
+AAAGCTATTCGGTTTAAACCATCTTCTATTCAATTCTGATGATTACTGTT
+AGGAACGAGTGGTCACTTAATTCAAAAGGTCGAACTGTTGTACTAATTGA
+ATTGGAAAATTTGTAGGTTATTTGACGTTTATCAGAAATTGAAGATTTGA
+TATAAAATTTGGTAAAAATGAAAAATAAAGTTTCATTTAGAGTAGTATTC
+TGGCTTCCCTTATAAATTGAAATGGAAGAGTTGGCCATATTGGTTCGGCC
+ATATCTGGGGTAGATTTACGGTGCGTTGCGTGTCGCGTCGCGGCTCGATT
+TTAGTTGTAAAACTAAATGTATTTGTCCGTGCGGAGTACACGACTTTCCC
+ACGCGTGGTCCGGAAGGCGATTGTCAATGGAGCGCGAAAAATTCAATGAA
+GAAGGCCAGAACTTCGTGTAGTATTAGCAGACCAGGTTTTCACATAAATT
+TGAGCGGTGAAACTAAAATTATGACATTTTTACGCAACTTTATGGGCCAG
+AAAATTTTTTTTGGAATTTTTTTTTGAAAAAAATTCAAAAATTTTGATAA
+AAATAATTGCCAAAAAGACAAATTTTGAGTAATTTTACTGCCTCTAAGAG
+TAATGAACAAATGTTTCCAACTTTTTGCAAATTACTTTCTTAGTTCCCTT
+GCAAATCTATATAGATTGAATTTGGCCTAAAACCTAACAATTTAGCTGCA
+ATATTGTTACAAAAATTTGGGTACAATAGTGTGTTTATTGAAACATGTGT
+TCTTGAAGTTGGGTAAGAACAATTGATGAAGGTTGTACCAAATGAACAAA
+AAATGTTTTTAGAGAAAGTCTGAAACATTACCTTATTTCTGATGGTCGTT
+AATCAAATTTTACTGTAACTGTTATGAAACCTTGGGCATCGTATTTTCTC
+TATTAGTGCAGCCGACCACTTTACTTTGAGACGTTATATCTTGTTTATTT
+TAAAGATCTCAATATTTTAATAACTACAAAATCATAGAAAAAGAACCAAC
+AAAAATTTTGTTAGTTGACAATTTTTAAATAGGACAAACGATAACTGAGC
+TATGAGCTGTCAAAGTTGAACAATGGTGGTGCAATAGAAGGAACTAATAG
+AAAAAATACGGTAACCTAAATTTTTATGTTAAAATAAGAAGTAGCGGGTT
+GATTCCAGAAGTTTTTTTTATAAGGTAACCATCCGCTGACCGCGCCTCCG
+GTATCCCTTCAAAAGGCAAAAAGTAAACTTTTCTAAAACTACAGTAATCC
+TACAGTAGTCCTACAGTACACCTACAGTACCTCTACAGTATCTTGACGTG
+ATCCTCTACCTACTCCCAACCCAGTACCTCTTCAAAGGCTAAAAAGTCAA
+AATTTCACAAACTACAGTAATCTTACCGTACTCCTACAGTAACCCTACTG
+AACCATTACAGTAATTTGACATTATTCGCCACCAACTCCAAACCCAATAC
+CTCTTCAAAAGCTAAAAAGTCAAAAGTTCACAAACTACAGTAATCCTACC
+GTACTCCTACAGTACTCATACAGTACTACTACAGCACCCCGAACATATCC
+CTCCACTAACCCCAAGTCAATATCACTTTAAATGACGAAAAGTCAATTTT
+TCCAAAACTACAGTAATCCTACAGAACTCCTACAGTACCCCTACAGTACT
+ACTACAGTACCCTGACTATGTCTTCCACTAACTCCAAACCAATATCCCTT
+CAAAAGACGAAAAGTTAATTTTTTCAAAACTACAGTTATCCTACAGTACT
+CCTACAGTACCCCTACAGTACTACTACAGTACCCTGACTATGTCCTCCAC
+TAACTTCAAACCAATATCCCTTCAAAAGACGAAAAGTCAATTTTTCTTTT
+TTTTAATTGAAATTGTCCGTTATTCCCTATTATGTAATTTTCCAAAAATG
+CTGCCAACCTCAAAAACTGTTATGTTTTTGTTCATACACATTTAGCCACC
+ACCTGCATATGACCCATAAAAAACCATACTTGACACCTGACATACTTGGT
+TTCGATACAAAAATCGAGAACATTTGGCAAACCTGAGTTGTCATTCTATT
+GGCTATTCACCATGTGCTCTAATAAAGTAGAACTTGGGAATATGTGTCAA
+GGCTGTAAATGGGGGAGTAGTATTGTTAACATATGTACTGTGCAATATTC
+CAGATGCCAAGTATACAGATTATCTAATGACAATAGGTAATTTGATTTTT
+CAGGTGCTATAGTGCTATATTGTTCCAAATACATGATTTTTTTTTAGAAA
+ATTGAGGTGTGGTGTCGAATGTCCCATAATTTTGGATAATCAATGGTCTT
+TAGCGAAATCCTAATTTGAAGCCGTTTAAAGCTCGAAAGTGCAATACATT
+TACAACTGCATTAGCGTTTTATTTTGCTCTGAAAATGACAAATACACAAA
+ATTTTGGATTAAACCGCCTGGTTTTAAAACCGAGCTTAAACAATTTTAAT
+TTTACAAATTAAAAAGTAAAAATTTTCTAAATTCCCTACACTAAAATTTA
+GCGTCCACATCACTTTCTACCCCTTAATTAATTTTTTACTACATTTAACA
+AAAATATTTTGAACCGGCAATTGTCAAAATTGCCTATTCCCAAAAATTTC
+CAAAACCGGCAATTGCCAAAAATTTTCAAAGCCGGCAATTGTCAAAATGG
+CAGCAAACTTCCAAAACCGGCAATTGCAGAAATTGCCTATTGCCAAAAAT
+TTCCAAAACCGGCAGTTGCCGAAATTGCCGAAACTGCCGCAAACTCCCAA
+GACCGGCAATTGCCGAAATTGCCGGTTGCCGAAAATTTTCGAAACCGGCA
+GTTGCCAAAATTGCCGCAAACTTCCAAAACCGGCAATAGCCTAAATTGCC
+GATTGCCAAAAACTTCCAAAACCGGCAATTGCCGAAATTGCCGATTGCCA
+AAAATTTTCAAAAAAATTTCAGAAATTGATACATTTTTTAATTGTTGTGG
+GAATTTTTTTTAATAAATTTGAAACATATCACATCCTCCTGTTTTCAAGA
+AAATTAATTCCTTCAGTTTCTGACGACTCAAATCCTCCTCAAATGCCAAA
+TTTATTTTGGGAAACTATACCAATTCTCAACAGAATTTTAAAGGTGGAGT
+ATTGCCATTTTGTCTAAGTACACTTATAATAATCCAAAACAACCGAATAT
+CATAGAAAAACACTCGAAAAAAAATTTTTTTGGTCGACTTCCAAAATTAT
+GAGTGGCAAAAACTGTGTAATTGCCACTTTTTGACAGTAAATTAAAAAAT
+TTCAAAAAAATTTTGGAACGTTTTATTATGATATTCGGTTATTTTGGGAC
+CAAGTAAGTGGTTTACTCCACCTTTAAAAATTTAGCCGTTATACAAACTC
+CAAATATATCCATTATTCTTTCCCCTATACCCTACCCATAACAAAACAGA
+AAAATTTCAAATTCGCATCGTCGCAACACCACAGCATGTCCATTTGGAGT
+GATGTTCCGAGAGAAAGGTCAAATCGTCTACCTCCTTATTCTAACCATCT
+CTATGCCTATATATGAGGCTTTAATGAACGAGCGCCGCCGCCGCGCGCCT
+AGCGCCTCCGAGTGTCGCAAAGTGCAACTTGTTTGCCACTTAACCTGAAT
+TCTACTGTGTTGTATTATGTGAAGAATCGGATAGATGTAATGTGTAACAA
+TAAAAAACCACGACGACGACTGAATATGGAATCGGCTAGGTGGTGCAAAA
+GTTTCGGAAAGTTTTGGTACCATGGTACCTGTGTAAGCTCTGTGAATTTT
+TGAGCCACGATGGGTCTTGCAACGATATTTCGTCGAAACTTTATTCTCGA
+AAGTTTGTTCAATTTAAATTTTCCGCAAAAAACATTTTTTGAAAATATTT
+TTAAAAATTTGAATTTCTCAGCATTTTTTTTTTAATATGAAGTTTCCAAT
+CCCTCAAAAAAAAATTTCAGAGAACATTTGAATTTCCCGGAAACCCCAAT
+TTCTGAGAATTTTTCAATTTCCCTTTAAAATAAAATTTCGGAGAAAATTT
+GAAATTCCCGCCAAAAATTTATTTTGAAATATTTGAATTTCCCGGCAAAT
+ATTTTTTTTTTTGAAAACTTTGATTTAACGGAAAACCCATTTTCTGAGAA
+TTTTTGAATTTCCAGTTTAAAGAAATTTCCACGGGTTTCTGGCTTCCCTC
+ATAATTTGAAATGGAAGAGTTTGCCAAACTAGGAAATTTTGGTTCGGCCA
+TATCTGGGGTAGATTTACGGCGCGTTGCGTGTCGCGTCGCGGCTCGTTTT
+TAGTTTTAAAACTAAATGTATTTGTCCGTGTGGAGTACACGACTTTCCCA
+CGCGTTGTCCGGCAGGCGATTATCAATGGAGCGCGAAAAATTCAATGAGA
+GGAGGCCAGAACCCCGTGAATTCCAGCAAAAAACTTTTTGAAACTATTTG
+AAATTCCCACAAAAAAACAGTTTTGCTGAGAATGTTTGAATTTCCCCCAA
+AAATTTGACGGAATACTTGAAATTCAAAAAATGTTGTGAGAATATTTGAA
+TTTCACGGAAAACCTGTTTTCTGAGAGTTTTTGAAAATCCCTCAAAAAAA
+ATTTCGGAGAAAATTTGAATTTCCCTCAAAAAATTTCGAGAAATATTTTA
+AATTACCGGCATATTTGACATTTTGAACTCCCCACAAAAAAATTTTTAAA
+AATATTCGAAATCCCGGAATAATTTTTTTCACTATAGTCAGAAAAGATCA
+ACTGACTAACTTTTCACAAACTACAGTACCCCGAGCATAACCCCCATTAG
+TTTCCGATAGCTACAGTAATCCTACAGTACTCCTACAGTCCCCCTTCATA
+ACGTTACCCTGATTACTAAAAAATGCCCTTTTAATGCGTATTATCACATC
+TCACATGATTAAGACCAAAAGGGGTGTCCTTCAGATAAATACCCGTTCAA
+TTTTTTTTACTGCAAACCAGTAGACTTATCTTTTAGGTTATGAAGAGAAG
+ACTAAGTGTAAACAAGGTCGTTGGAAGTGATATGTTAAGAAGTTAACGGC
+AAAATCGATGCCAAAACTTTCTGAGCTTTGACTTCTACTGCTCAGCTCAT
+TCCATAACCATGAGCTCATCAACTTGCCCTCCCCCCCCCCCCACTATCTT
+CCACCACACTTTCATTCCTCATTGTCGCAACAAACCCATCTCCGGATTCG
+TCCTTTATATGTGTCACAACACAGGAGTACTCCTTAGCGCGCCAACTTGT
+AATACCCCCAGCGACTTGGCCCAGAAACTTTCCTCTAATCGCATCCACAA
+TATGGTCTGCAAGTACAAGATTAGCACCCCCCATTGTATGTCAATTTGTC
+TAGTTTTTTATTCCATTGAACTATTCCACAATGTAGAAAATTGGGGTTAT
+GGTACATCGAAACATGGTGCATCACATAATGGTGCGCCCAAATCATGGTG
+CATCGTCAAAAATAAGAATCCGAGTCCTCCCAGACATCCATGTAGGTATG
+CACTTTCCCGCCTGTTCCGCATCTAACCAACGATTAACTGAATCTTTACG
+ACCCTCTCTCCTCCGAATGATGTTGAAAAATGTCGCGCCAGCACCTTTGG
+AGGGGGGGGGGGGGGGGTTAAAAAGATTCCAATCTACCACCTATCTTCTC
+CATTTATCTTCAATTTTGCCCCCCGCGCTCTTAGATTAAATGAACTTTTT
+TGGCTAAATCACAGCACTTTTTATTAAATCTAGGAACTGCATCTAAACAA
+TGCATGTGGTTACAGTTACCGAAAAATGTTGAAAATTTGGGAAAAGTGCC
+AAAATGTTGAATCAAGTCAGAGAGATTCGAAGACGCTTCTAGCAATTTTT
+TGACAGTTCCTGTCCCCTTTCGGTAGATTTGCGGCAATTCTCGGCAGATT
+TACACCCGCTTTTGGCGGTTTTTCGGCAACTTTTAGCAATTTTGGCAATA
+CTTGAAAACTTCTATTTAGCAACTTTTAGTCAATTTTCTGTAATTTCTGA
+GAACTTCCGATTTTCTTTTACATTTTTTTCCGATGCACCATGTCCCGAAC
+GCTCGCGCCACGACTTTTTTATTCATTATAGCAGGTCCTGTTTTGATGCA
+CCATTTCCCAAAGAGCCCTGCAATGCTGGCTCATGTCACGATGTACCATG
+TCCTGAAATGTCCCACCACGTTCCGCAACGAGGTTTTACTGCCAAATTTT
+ATGCAATTCCAAAATATTTTTCGACAATTTTGTTAGCTTTTCCCTTTCAA
+AAAAGTTCAAAATTCTGTTCCAAAACCACACCAAAAAGTCGAAGATCCGC
+AAAATCTGCACTTGAAACACTATTTGACAACCCCCGTCTCAGGCTATCAA
+AAATGCATGCAGTCATATATATGTGCAGCTTGTGAAACAAAAAACGAGAG
+GGATCAGGGGCTCAGTGCTCAAGGTAGATGTGCAACTCTATGAAATTGAT
+CGGTTATGCATGGCAAGTAAGAGTGACAGGGAGCGAAGTATGATGATGAT
+GATGATGATGGTGTGGAGAGAGCGCAACGTATGAGTTATTGAATTTTCGA
+GAAAGGTTATCTTTGATGGGGGGGGGGGGGGGGGGGGGCAGTTCATGGTG
+CATCGAAATATAAAAACTTTCGTGGAGATACGCTTTTTGAAGAATTTTGT
+GACACCTTCTTGGTGCATCGAGACAGTTTTCGTGGCAAGACCTGATTTGG
+TTGAAACTCTGAAGCCAAATCGCGCTCTACGATTTTGTGACCAGGCCAAG
+GTTTTGGTGGCATGGTGCATCATAGTAAAAATTCAAATCCTGGGAAAAAA
+AGCTCTATATATAATATCCAGCCATGGACCGTACCTCCGGCGTGGCCCCC
+TTCTGGAGCTAAAAACTAATTTTTCTAAAACTACCGTAACCCTACAGTAT
+TCCTACCGTACCACTATTGTACCACTACAGTACCCCGACTATATCCGTAC
+ACTAACCCCAACTCACTATTTATCCAGAAGCCAAAATTTCACAGACTACA
+AAGACTACATAGACTACAAACTATGAACACACTGAATAAGCGCTTCATAT
+ATATAGTGAATGATGGTGAGATCCATGTGACATGGTGCATTGTGACAGGC
+ATTTTGGGAAGGGGGCTTTGAGCACAAAACAAAATCTTTAGTTATTTTTC
+CGACAATTTCCAATAAAGTGAAGTTTAACAAGGTCGTGGCGTACTTGTTT
+CCAGTTTCCTCACGAGTGTTGCATATTATACCGCCAGTAATCATTGCGTT
+ATCACATAGTTGACAACGGTTTGATAATGTCACAAAGTGTGGGGGTTTTG
+GAAGTGGCATCAAACCAGCATACGATTATTAGGACGTGATGAACTTATTT
+TACCTGAACATATTATTAGGTGGTGGAGCTGGGAGCTTAGTATTTGGGTT
+TTGAAACAATGCACCATGTCCTAAAAGATGCTTTATTGCTAGGTAGGGTG
+CCGCGACTTTTGTATTCATTATAACAGGTTCAGTTCCGATGCATCTGCAT
+TTTTTTAATACTGTTCTTATTCTTAGCTCAATAATTCAGGCTGAGGGCCG
+CAGGCCCGAACACTTTTGGAAACTGTGGGCCAGCTTTAATCCTATTCCAA
+GCAAATTGTTATTCGCTCAAGCCAACTAACCAGATTTCCTCAAACTTTAA
+TCGCTCATATCTCAGCTCAAAACCATAGCAGAGACTTCGTTTTTTAATCA
+ATCGATCCCAAATTTTAAGGAAATCTCGAATATCCCTATCTCAGGTTTGA
+GGCGAAGCCGAGAACCTGCGCAAGCTACCTTTTTGGGCATCCCCATTCCC
+GAAAGGCTGGCGCGGCCCTGCCGCGCTAGTCATTTGCCAAAACGTCAAAT
+TGGGTCATGTCACGATCCATAATGCCTTGAAGGGTTCTTCTGCAACAGTC
+CTAAAAGAAACTTAGCACTCTGGTTGAGGTATAGATGCACCATGTCCCAA
+AGGGTCCTGCCATGTTGGGACATGTCACGATGCACCATGTCCTGAAAGAT
+CCACGCTCGAAAACTACATTGTTCCGAGTGTTTACCTCTATTTCAATACG
+AAATTTCAGCAAATTTTCATCCAAAATCATGTCATTCTAACAAGAGCCTA
+TCATGTTGACTATAGGGTCGTGACGACCTGCTCGAGTTCGCCTCGCTCTC
+CTGTTATCAGAATAGCTATGCGTTAAGTACGCGATGTATTGACAGTCACG
+ATTTAACGCTTCAGTTTTGTAGTTTTGCTGGAAATTTTTGAGTTTTTCGT
+TTTTTCTTGGCTCAAATCGAGTTTTGCTTTTTTGACGATTAAATAATTTA
+TTCAAACTTAGCGCATTTTTTGACTGATTGTGAGACATGATGCATCGTGA
+CAGGGCTTAATCGTGGCGAGACCCTCTAGTACAAAATTCTTTTAAATATC
+AGTAAAAGCATTATAATCCATGATTCTATACTTATTTTATGGAATTTTCA
+GCCTTAAAAAAATCTGAAATTTACGATGCTAAAATCTACTCAAATTATAG
+TTTCAATCCAAAATTTCTCAGAAAAACTAAAATTAGCATAAAAATGTTTT
+GTCTGAAATAGCCCTAGATTCAAATATCCCTAACACCCCAAAAAACACCA
+ATGTACATCTCCTCTCCGTAAATATGTAGTTTTACAACCGCCTCTCTGTT
+GACTGGGAGCCATAAATGTAGATATATTATCTTTCCAGATCGCCTGCCGG
+CCCCTCCCACCTGATTGTAAAACTGCTCTTTGCTGTGGCGTTTTATCGAC
+TTGTTTTTCTTATATATTCCATTCTACATACCTTAACACATTTTCTTGTA
+TATTTTCTATACACTTTTTTAACTATAAAAAAATGCAACTCCTTTTTCTT
+CGATTTCTTTTTATGCAAATTTTTTGGCTTAAAGGTGGAGTAGCACCAGT
+GGGGAAATTGTTAAAAACCACTCCTTTGGTCCGAAAAGTACCGAATATCA
+TAATAAAACTTTTCAATATTTTTTTGAAATTTTTTTATTCACAGTCAAAA
+AGTGACAATTACTCAGTTTTTGCCACTCATAATTTTGGAAGTCGACCAAA
+ATGTTTTTTCTAGATTTTTTATAATGTAATTTTGTTTTAATTATTTGTAT
+TAAAACATTGTAGGACAAGACAGGGCCGCAACATAAGATATTGCTTTGAA
+TTTCCTCAAAAGCTCATATTTTTCAGAATTTTGGCAATTTGCCAAAACTT
+GGTATTTAAAAATTGTTAGAGATAACTGTATTTAGACAAAACATAGAACA
+TTTGTATTTCAAAATAGTTCAAAATTCTAGTTTTTGAAATTTTGCGGCCA
+GACTGACCCCCACGATGCACCATGACAAATTGCAATTTTTTTTTCAAAAA
+TTGTTTTCCAAAGGGGCGTGTTCCAAACATCTGACCCAAGTTTTCCCGTA
+GTTCTTCTCTCCCCCAGCGGGGTAAACACTGCACTTTACGACTCCGCCCA
+GTGCTTTTTTTTTCGCAGAAACTGAGAGAGAAAGAAACATCTGCGTCTCT
+CTCCCCCAGTACGCTCGTTCCCGCCCCCCACCTCGATCTGCCAGACCACA
+CCGACCTGATTCGAGATTCCTTTTCTTATATGTATATGTTTTTGGAGAGG
+TGATCTTGTTTTTTTTGTTTCTCCTTTGGTTTTGTTCTCTATGCTCTGAA
+CTTTGGTCTCCTACTTTTCTACAGTTTTTTTTTAAATATCCAAATTTTTG
+AAATAGAGGGTTGATCTACATGACCCCCATGCTTAGTCTACTATAATGCT
+ATATCTGATGTTCCTCCGAATGGCCTGGTAGGTGAAGGCTTTTAGCCCAG
+TGAGCCGGCTTACCAAGTCTAGGACCATGGTTCTTACAACTTAAGGCCCA
+AAAAAAGCAGGCATCTGGCCTAACTTCCCCCTCACTAAATCTGTAGTAAT
+ATATAATTTCTATCATACTCCATCTTTTTTTTCTACCTCTTATCATGTTG
+TTATTGAGCAGCAACGCCCTTATATTGTTTGGTATATATATTTGATATAA
+AACCTCGTAGTAAATTTTATTTTACACAACAACATTTATTATTTACTTTT
+TTCATACTATTTTTTTTTTGCAGAACGAAAAAAAAATGCTATTCACAATT
+GAGCAACTGGAGCTCATCAAAAAGCTGCAGCACACCGGGATGTCATCCGA
+TCAGTTGCTCAAGGCTTTCGGCGAGCTGGAAGTTCCAGAGCAGCTTCAGA
+ATAACAACACAATTGCCGCAGCCCTGTACAGCCCACTCCTGGTCCAACAT
+CTCACAACACCCAAATCAGAGACTCCAGTCAAACTCACCGTGCAGACAGT
+GCCGACACCTGTGAAGTCAGAGCCACAATCTTCAAATTGCTCATCACCAT
+TTGAGCATCCGATATGCTCGAATGCTCCGCGGCCGATTAGGAGTCAGCGA
+ACGCCGATGAAGGAGATTACCACACTGGACGATCCGAATGAGCTGGAGGA
+GTTTATGAAGCAGGGCGAGGAGGCGTGCATTTTGGATATGAAGACGTTCA
+TCACACAGTACTCGTTGCGGCAGACTACGGTAGCAATGATGACAGGTTAG
+TTCCCAAAAAAGTGTAGTGGAAGAGTTTTTTTTCTAAAATCTAGGCCGTG
+ACCAGAAATAAATCAGAATACATCCCCGGCGCCTAGATTCCTAATCTCTG
+CTGTTAGCCACAGTGCAATTGAGTATTACTGTAGTTGATTCCTTCTATGA
+CGTCATATGAAATAAAGTTGGCTAAAGGGAAAAGGGGACTCTGGATCTTA
+GGCGAGCAATTCTCTGCAGCCGGCACCAGAATCGATCCCCCGGTGCCTGG
+ATATCTATCCTTCGCTGTTAGCCACTGCGATATGCCCCACCCGCGCTGAG
+ATCGAACCGAGGCGTCTGAATTCCTAGGCGAAGTTGCTACCCACTGCGCC
+ATGTCAATCTTCTAAATTTCCAGGAGTAAGCCAGCCGTACATTTCAAAAT
+TGCTCAACGGCAACCACCGTGAACTATCGCTCCGTTGCCGTAAGAACATC
+TACTGTTGGTACCTGAACTGCCGACGTCATCCCAACAAACTCGCTGCCTT
+CCTCGCCGATCCGACAACTCGCCTCGAGACGAATGGAGATGGCGAGCTGA
+TCCCACAACGTCGAGAACGCTACGTGTTTCGTCCAATTCTGATCCGAATG
+CTCGAATCGTTCTTCACACAAACGCCATTCCCAGATCTTCCACGGCGAGT
+CGAAATAGCGAATGCTTGCAATCACGTTCTGAAGATGGATAAGAAAGGTG
+TTGGGTTGATGCCAAAGGAGGTGGTCAGCCCTCAAGTCGTTTCGAATTGG
+TTTGCAAATAAGCGGAAGGAGTTGAGAAGAAGATCCGCTGAAGCTTCGGC
+CGCCTCCACCTCGTCCGCTTCGTCTTCTGCGTCATCGACTGCTAATCATG
+ATTCTGTCAGTGTGTCCAGCATGAGCCCTCGCGATGAAGAGGTGAGAGTT
+TTAATTTCTCGGCCACGCTGTACTCTGGGTGGAAGAATTTTTTCTAGGTC
+TTATAAGGAATCGCCCTCCGGTTTTCCCACAAGTTAAGTCATAAACATGT
+ACCATCTAGAGGTTAAATTTCTGGAGTTTTATTTATTTGAGAGTGATGGT
+AAACCTGTCAGTCCTTGGCAAACATGTGTCTGTTTGGTCTCAAGGTCTAG
+GTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTAGGTCTTGGT
+CTAGGTCTAGGTCTAGGTCTAGGTCTTGGTCTAGGTCTAGTTCTAGGTCT
+AGGTCTAGGTTTAGATCTAGGTCTAAGTCTAGACACAAATTTCTAGGCCA
+CGAAAATTTCTGCCGTGGCCTAGGATTTTTTAGGCCATATTCTAGGCCAT
+GATCCAAAAAAAACTTTCCCTGTCTCCTCTAACCCATTTTTTTTGCAGAC
+AAGCTCCCGTAACACAACCCCGGAGACAGCAATCTCCCCGTCACCAGCAG
+TGTCCACTTTTGAAGTGTCCCGCCCGTCTGCCATCATCTCTGCCACGTCA
+TCAACAACCTCGCCAATCTCAATTCCAGCAACAATCATTCCATCAGTATC
+GCCGTCAGCTCTCGAACTTTTCGCCATGGCCCAACAGCTTGGAGTTCAGC
+TTCCGGTTCCATTTCCAACATTGCCAACACACTTTTTCCCGTTTCAAATG
+GCTCCGTTCTACGGGAACCCGGCTTCTATTTTGAAGTCTGAGTGAAGCAT
+TTCTAATTTTCTTTTCTTCTTTTCTACACCAATATCTTTTTTCCATTTAT
+TCAACTTATTCTTCATCCCATGACACGAAAACCTCAATTCTTTCATATTA
+CAAACGATGCTCCGTTTCTTACGCCCTGCCCCACACACGCCCCGTCGTCC
+AAAAATCAATCAATAATCGATTTTTCATAATATTTAATTTGTTTTTTTTG
+TGTTTCACTGCTGTTTTAATATTTGAAAAGTACGAGTTTCTTCAAAAACA
+TTTTTTGAATAATATTTGCTTCACACTCCACGCGTTTCGTAATGTATCGC
+TTGCCCTGAAATTTTGTTGGAAATTCCATTTTTTGTGCAATTTTTGTTAT
+TTTTCAAGCGAGAATAAATATTTTCTAGTTCTAGAATTCAATGAAATACT
+TTGCAAACGCGCCCCATTGCACTTGACCGAGGGGTGAAACAAGTTCAGTG
+TTTTCAAGATATTTTTTTTTAAAAACTTGAATTTGGAACAATACAAAAAT
+CTGTAAAATGCAACAGTTTTCCAAATCTTGTCCACGTGGAGTACACAATA
+ATTTTTCATCTATACGGAAAGATTTCAAAATTGGAATGTTAAATTATTTT
+GTGGTTTCTAGGCCATGGGAAAACTAGGCCATCAAAAAAATTCCAGAGTG
+ACCTGGAAGTTCTAAAACTTTGTTGAAACTTGTCCACGCGGAGTACACTG
+GTAGTTTATCAATAGAGCGCAAGTAATAATCCCTTGGAATTTTCCTTTCA
+CCACCCCCTCTCCATTTTATATGAGAGTTTTTTCCCTCGCAATTTCCCAC
+GCTCAAGAGGGTGGCCGCCATTTTTTTTTTGAGGGGGGTCGTATCTAGAT
+TTGAAACACGTCATTTATGCTCAAAATGTGCCAATTTTTATTGTTTTTGA
+GTTTCTAGGCCATTTTGGTAAGTTAGGCCGCATACTGACTTTGCGACTTC
+CAAGGATATGGCCTAGCTTTTTTTTCTAGGCCATATAATTTTTTGAGTTG
+CAACTGTGGCCAATGTTTTTTTTGGGTTTCTATGCCACTTGTGAAAAGTT
+AGGTCATAGAATAACCTTACGGTAAACGGGTCCTCACAATCAGGAATTGT
+GGCCTAGTTATTTTCCTAGACCACGTTTGATTTTTGTCTTTCTAAGCCAG
+GTTTGGGTCTAGCTCTAGACCTAGGTCTAGTTATAGGTTTAGGTCTATGT
+CTAGGTCTAGATCTAGTTCTCTCACGTGAGAAAATTAGGCCACCTTTCCC
+CCTAAACTCTATGATCTCAAAACTAAAACTACTTTCTAGAAAACTCTTCG
+AAAATCATAAAACCAATTTTTTATCACTATTTTCATGCTAAAATCCAATC
+AGAAATTGATCAGAAACACGCATATAAATATTACGACTATAAATTCATTT
+CTTTTTTTCATTTTTCCCTCCAGAAGGCTCTTGGCGAGAAAAATCTGCAT
+ATTTTTTCTACTTATATGTGTCGAGACATGTGATATTCCGGCCGGCGGTG
+GCTCTGAATGAATATTCAATTGAACGAGAAATATATATTCTCTCCAGAAG
+GCGTTTATATTATGTGTTGCTCCTGTTTCTGCTGTATTCGGCGTGGATTT
+GGTATGCTTCTCAGTGGAGTGCAGTTGCAGCATTTTTTTTCTTCAAATTT
+TGCAATACTCTCGAACTTTTTGCACTTTCAAGCCTTTTTTTGGGTTGCCT
+AGAACACTAGAATTTCTGGACTATTTTGAGATTTCTAGGCCATTCTTGAG
+ATTTCTAGGTCATATTGTGATTTCTAGTGCATTTTTGGGTTTCAAGGCCG
+AATTGGAAGTTTTAGGCCATTTTTCGGTCACATTTTTAGGCCACTTTGAG
+GATCTTGTGCCAAACTGGGATTTCTAGGCCATCATGGGATTTTTAGGCCA
+ATTTCGAGTTTTCCAATCATAATATAATTTCTAGGCTATCTTGAAATTCC
+TAAGCCAGTTTGGAATAATTAGGCCATCTTGGGATTTCTACGCCATTCTC
+GGATTTCTAGGTTAAACTGGAAATTTTAGAATTTTGGGGTTTTAGGTCAT
+ACTGCGAATTTTAGTCCACGGTTGGATTTATAGGCTATCGTGGGATATCT
+AGGCCGATTATGGAATCCTAGGCCAACTTAAAATTTCTAGGCCATTTCGG
+GATTTCTAGGCCATCACGCCTCCTAAAAGGCACAGACAAAGTTCAAAACC
+CACCAGAAAAAAGTGTGGTGAATTAGTCAGCAACACCCCATTTTTCTTTT
+CCAAAAACTAAAAAAAAAGATACCCCTGACAGATATGGGCAGAGATGGGG
+GTGCGAATCCTGAAATTTCCGAATTCCAGTGGGAGCTTTTTGTGCCAGAA
+AAAGTAGTGGGGGCAAGTGAGAATGTGTGTCGCCTTCCACTTTTCAAACA
+CCATTTTGTCCGTTTCGCCGGCCCGAAAATAGGCTTGAAAAGCTGTGGCC
+TAGAATTTTTTCTCAAAATTTTTGACGTGGAAGAATTTTAAGATTTTCGA
+GGCCAAGAGGTGGCCTAGAATTCAACATTTATTGGCAATTCTTATCTAGA
+TCCCGAACCCCGACCAGTCAGTTTTTAATTTCCGGTGTCTGAATTTTTAA
+TTAAAAATTATTTTTGGGAGGAGCTCCTGTTTTTTTTTCGTCAAAAAATG
+AAGGTGGCCTAGCTTTCTCATTTTAAGGCCACGAATTCTAGTTAATTTTT
+TGTTGGCTCATTTTTTGTTTCAAAAAACGAAAGTTAGTCAAAAACTTTTC
+TGCATATCAAATGCTCTTTTTGAGGTTTTTTCCTGCAAAATTTTTCTAAG
+AAAATTTGAATTCCCGCCAAAATTTTTCTCAGAAAATTTGAATCGCCGCC
+AAAATTTTTCTCTGAAAATTTGAATCGCCGCCAAAATTTTTCTCAGAAAA
+TTTGAATTCCTGCCAAAGTTTTCACAATGGGTCTCACCACGAATGGTGAC
+AGACCCCGCCCACAATTCTCAGAGACATTGGGTGTGTTTTAGACCAAAAA
+AATAGTTTTTTTGACAAAAACAATTTTCCAGCAAATACTTGATCAGTTGT
+CATTTGTCTGTTGAAAGTGGAAAAAATAAAACATCTTTCCTTTTTTCTGC
+TTCTCCCCCTCCTCGTCCTTTTTGTGCTCAAAACTCAAATGGCTCATCTC
+AATTGCATGACAAATTAGCAAAAGATGAGAGCAATTTTTCCCTGTTTCTC
+TTTTTTTTCCTCCGTTTGGCTCCTCCTCATGTCTTTTTTAGTAGTTTTCA
+GAGTTTTACTATTGAATGTTCAAACTGGCTAAAAAATTTTGATTTTTTTT
+TCTTTTTAAACTCTTACGAAAATTTTGATATAGGTTAGAAGCCTAAAATC
+GACGGCCGACAGCGTTTACATTTGTGGCCTAGACTTCCAAGCCTTGGCCA
+TGGCAAAAACTTGTTTAGCCTACCTTTTCAAATAGTGGCCTAAAAACCCT
+ATACTATTTCTGAACTAACTGTTTACTCAAAAGAGAAAGTTAGTGGCCTA
+ACTTTCTGAATGGTGGCCTAGAAAACTCAATTTTGGCACTTTCATGACCG
+GTCATCAACCTGACATTGATGGCCTAAGTTTTAATGAGTGGCCTAGAAAA
+CCAAAATATGGCCATGCGCTCAGCATGATCTAACTTTCCAACTCTGCTAT
+AAATTCCTTGGGGGAAACCTCGGCCATCACGGGTGGCCTAGAAAACTGAA
+ATTCGGCCAAGACCCCGTAATTCATGGCCTAACCTTTTAAAAGGACAGCG
+TTTGGCTTTGGTGGCCTAGTTTTTTGTGGCCTAAGTTTACAGAAAAAATC
+CTCAGCCACAACCTTTACCCTATACATGAAATCACATAAAAATGTCCAAA
+TATTTTCCAATTAAATTTCCAATTCTCCACCCTTAATTCTTCATTTTCTT
+TTCTTCTTTTATTCCTTTTTCACTCTCTCATTCTGAAACTAATCTTTTCA
+ATTCTCAGCTTCTCTTTTCTGGTGTGGCTCATTTTCACTTTGCTCCCGCC
+ATTTTCAATAGGATTATCCGTGCACACACACACATGGCTCAGTGAGCAAC
+ACCAACAAAAAAGAGCATATATAGATATACAACGATATCTAACTAGTTAC
+ACAGGAGCTTCTGTTGTTCTTCTGTGCCCCTCCGAGCCGAGACAAACTTT
+TGGAAAAGAGCAACGCTTCTGGAGCCGACATATTCGAGAAATCCCGGAGA
+CAATTGAGACCACTATGAGGAAATGATGGTCGAGGAGGAAATGAGAGATG
+GCGTTGCTCAAAGTGCGCGACGAATGCACCAAGTTGGTCGGTTATCAGTG
+AGTTTTTGTTTTTTGTTGGCCGAAGTAGAGATAACTAGGCCACCTAGGTA
+GGCTGACGATCTTCAGTTTGCAAATCCTCTTCCACCGCACTTTTTTGAGC
+GATCTAGGTTTGCAAAAGGTAGGCCGCCTGGTCCACCGTACCTGTCATGA
+TGGCAGAGGTCTGGGAAAGCTAGGCCACCTGTCTGAGCTGATGGTCTAAG
+GTCTAAAGTTTACCAAAAACTCTTCCACCGAAACTTCTAGGGCGACCAAG
+GCTTGCAGAAGCTAGGCCACCAGACTTGGCTGGTGGCCTAGAATTTTCAA
+GAACTCTTCCATCGTAAATTATTAGAAAGCCGCGATAGGAAAAAGCTAGG
+CCATCAAATTACCTTAGTGGCCCAGAATCTATAAAAACTCTCCCATCGTA
+CTTGCAAGGACGGCTGAGCTTGGAGGAAGCTAGGCCACCAGAATAGGCCA
+GTGGCCTAGAATCAACAAAAACTCTTCCACCGTACCTCCTACAATGGCCG
+AGGTAGGGAAAGATGGGCGCCAGGCTAATCTAACTTTCCTAGACTGACCT
+AAATGGGAGAAAACTAGGCCACCGGGTTTACGGAGTGGCCGAAAATTTAC
+AGAGACATTGCCCTGACTATCTGACTGTTTTTTTAGCGAAAGAACTTTCA
+TATTTTCTAGGCCAGGGGCCCCCTACGCCCCAACACAATCCAATTTTTTT
+TTGCAGATTTCTAAACTCGCACATTTGTCTCTGCATATCACTCATCCAAC
+TTCTCGTCTGCTGCTGGGCCGTTGCTCAGCACGTCAACTCCTACATGACG
+CACAGTAAGGTGAGCCAGAGTTCATTGGAGCGAATTTGTAACCAGAGAAA
+ATTCAAAACTTAAAATTCAGATCTTAAAATGTGATTTTCTGGAGGGGAGC
+CTCCCGCTGGAGGCCGTGGACGCTGTAATTTTCGATATCCGACTTTTCCA
+TTACCTATGGGGCATTCGAGGATGTGTGGCAGAGTATTTGGATGGTGGTG
+GGTACTTTTAAGTTTCCCACGAATCTTTACATTTTTCAGGCTTCGGGCGA
+CTTTTGTGGTGCGTTTCCCACTGCTTAACCCTGGTTTTCTCCATTCCGGT
+CACCTTCATCTCCCATCCGAAACCCTGTCTCTTTTGGCCGCTGCTTTTTC
+AGGTGAGTTGGCTGAAAAAATTTGGAAAAAAACTTTTTTTAAATTTTTTC
+CGAAAGGCGCAGTGGGATTTTCCACGACTACCACTCACAACAGCATGGTT
+CGAGTCCGCGTGGGTGTGAATTTTTTTTCTAGTTTTTTTTTGAAGTACGG
+AAATTGTATTTAGCCTTGAAAAATTCTAAAATAAGCAAACAAAAAAATCT
+CCGATCAAAAACCAAGTAATCCGTCTCCAAAAAGCGCAGCAACGTCAAAT
+GGTCCCACGGGGGGCCTGAAACGACAAATTTCCTGACATTTGACGGGTTA
+TCCATCCGCCACCCTCTCTTTTGAAGGAACATTGACTTTTTCCGTTGAAA
+TGGATAAAAAAATTGAAAAGAATTAGATAGATTCGGGAGAATGAATATGG
+TGGCCTAACGTGGTGCTTGACCCATGGCCTAGAAAACCAAAACTCGGTCA
+TCACCCTGATTGAGTGCCCCTTAAGAGATTAGGCCACGTACGACGCAATC
+CTAGGCCACCAATAGTTTTCTCGGCCACAGCCACCCCAAACAAAAATCTG
+AACTTTCTGATCCTTTACATCTGTACCCACTGAACCGTTTGTTTATCTTT
+TTACTCGCTCCACGGGAGCAGAACTTTTTTTTTGAAATTCCACAAAAGAA
+TGGGACAGACACTAGTGTATTTTGTTTTTTATTCAGACATGAGCCAGACC
+AGAAATAGGATTGAATCTCGGATTTCAGAGCCTGGAAAAAATCGGAAAAA
+ATCGGAAAACTGTGGGAGAACTGAGTTGGGTGGTAAATTTGGCAAATTGC
+CAAAATTTGGGGAAATTAACTTTTTCGGTAATCTGTAACTACAGTTTTCC
+TAAAAATGTATGAACCTTTTAGTGATTCTGCATAGTTTTTCAGGTCTTTA
+AAATTGAACCTACAGTACCCCGTACAGTTCAGAAGATTGCAAAATTCCAA
+GTTGACCACTTTTAAAGCGTGTATCTCGGCTGATTGGGAAAGTATCGGAA
+TATTTTAAAATACAAATTTATTGTTGGAAAATTTTTTTTTTACTTAAAAT
+TAATTAAAATTCAGCTTTCAAAAATGAGCAATGTATTTATAGATCCCATG
+CAACTTTGAAATTTTGTATATCCGTTCAGTGTAATGCTATCAAAAAATTT
+TCAACTACAAAATTATAGTAAAATTTAAAACAAAGAAATTGTTAGTTGAC
+AACTTTTTAATGAAATAAAGTACAACCGAGATATGAGTTCTCAAAGTTGA
+GCTACTTTATCGGCAACCACAATATAAGTCGCCCCCGTACAATGCACCAT
+GTGGTAGAAAATTTCGGTTTGATCTACTTAGATCTACAAAAAATGCGGGA
+GAAGAGACGCAGAGTTTTCTTTGCATAGCTAAGAACGTGCTGACGTCACA
+TTTTGTTGGGCAAAAAATTCCCGCACTTTTTTGTAGATCAAACCGTCGTG
+GGACAAACTGGTACCTCTTCGTTTTGTTGGTATGAAAATTTTGAAACTCA
+CTTCGTTTTGTTGGTATGAAAATTTTAAACTAGAAAAGCCAAAGTTGAGC
+TAGGCGCTCAAATTTGGTAGCATTTACTTTTTTCAACAAAAAAATAGCTG
+GCCGAGCTTTCCATTTTTACGGCCACGTTGCAATAAAAATCCAGGAGGTC
+CATGTCATCAACAAAAGTGCAAGGATGTAAAACAATTACACCGAAACGTT
+TGTCGGGAACTGCTTTTTCAAAAAAAAAAGGATCTCTCCGAACACATGTC
+ACCCCCAGGGTTCTAGCGTCTCCCTGACCTCGCGAGCTATTTCCTTGAGA
+CATATCTCTCCGAAACCTTTTGTAATGGTTGTTTCATGTTCTTCTTCATC
+TTCTTCTTATTCTTCTTGCTGGGATAAGCAGTTGAAGAAAACGAAAAGAA
+CACATAAAACACAGGCACACACACACACACATACACACCGTAATATCATA
+TAAAAGTGCGTCTGCGTCTCCCAGAGCGCCCTGGGGGTAAGGAACGCGGG
+CGCCCGCAAGGAAAAAGTGCAAAGAAATTAGAGAAAAAAGACCGGTCTCT
+CACTCACTTCTCGATCCCTTTTCTTCTCTAACTATAAAAAATGTGTGGCC
+TAACGAACGAAAGCGAAAAAAATCATCGAGAGAAGTAGTGAGAGAGAGAG
+AGAAGAAAGAGTTTTTTTGGACGCCGCCGCAGCTGCCAAGCATCAATAAT
+GACATGCTGGAGAAAAAAATTCCAAAGTTTAAATGTATTGGGGATCAGAA
+GCCTAGACCATAAGCCCCTTGTAGAGTTTTCTCGGCCATAGCCTTTTTGG
+TACGGTACATATACATAGAGACTTCAGATTGGGAATTGCGAATCTGTTAG
+AGTAAGAATAGGCCTAAAACATTATTGGGCCTAACGGTGACGGAGACTAG
+GCCTTGTTGGGAGCTTAAACTATGACATTGCCTAGAACGTTGTTCTATCT
+TGGTTATGTGGTGTCGGGCTTTCATGATCAGCTCCTCTACTTTTGTCCAG
+AGAAGTTTTGGACTTTTTCTATGGGTGCTTTGGGCTCTATTGCACAAATA
+GGTGATCTTGCGCACAACACAACGTAGATCAAATTCTTGTCTAGGCTCTG
+CAGGCTCCTGAGAGGTGTTTTGTACAAGCCCAAAGCAAAAGGATCTCAAA
+ATGTTTACAGGACTTCAAGCAGAGGATTTTTCGATGATTGCCAAAAATTT
+TGGAACTTTTATAGGCTTAAGCTTATGGTTATGTTTAGGCGTAGGCTTAG
+GCTTAGGCGTAGGTTTAGGCTTTGGCTTAGGCCTATGCTAGGCCTAGTAC
+CATAATACTATTCTTACCGCCGCGCCTGATCAAACCAAAGAGTAGGTCAA
+CAACCAATATTGACTTGCACTTTTTGCACGGTTAACTATATTACGCATAT
+GGCCAATTTTGTTAGGGAGCATTGATTCATGGAAAAAATTTCGGAATTTA
+TGAATGTTCAATTAAACTGGACTACGACAATTATTGGGTTCAAACATTTG
+AAAATTTTTTGGCCGACGTCGGAACGTCTCACTTTTTCCTGATTTTTGTA
+GTTTTTCCTTTTTACCGAATTTTTAGGAATATCTGGGAATTTCTCGTTTT
+CTGATTTTTTTTCAATTGTTTTTAGATCCCCCAAGCCTAAGCCTAAGCCT
+AAGTTTGAGCATAAGCATAAGCCTAAGCCTATGCCTAAGCCTACGCCTCA
+GCCTAAGCCAAATGCGGAGCCTAAGCCTAAGCCTAAGTCTAAGTCTAAGT
+CTAAGTCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTGCCGGAGCCTAA
+GTATAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTATGCCTAAGC
+CTAAGCCGATGCCTAAGCCTAAGCAAGTTCCGACATTTTCGACAATTATC
+TAAAAATCCTCTGCTTGAAGTCCTGAAAATCTTTAGGGATCCTCAAGTTT
+CGAGTTTGTACGGAACGGCCCAAACGCCTCTTGGGAGCCTGCAGAGCCTA
+GACAAGAATTTGATCTATGTTGTGTTGTGTACAAGGTCACCGGTTTGTTG
+TGCATCAGAGCCCAGAGCACCCACAGAAAAAAGTCCAAGAGTGTATAGCC
+TACGGTAGTCCTTGTTTAGGAGACATAGACAGTCTCTTTCTCTAACGGTT
+TTTGTTTATTCTTTTTTTTTCTCCCCCTACTTTCCGACAGACATTTTCAT
+CTTCATCTCCTTCTGCTGCGCGAATTGAATGGTCTATAAGTGTCTGCGTC
+TCGCCGATTCGTACAGTCTATCGCTTTGAAATCGTCACCCCCAGGCAAAC
+AGGACACCCGAACACACACACAACTATCCTCATTCTCAAAAAAATGGCTT
+CACTGCATAAAAGTGCAGAAATTAGAGAGTATGCGGAGATTCGGAGAATC
+CAGAGAGAACACACAAACACACTCGGAAACTCATATAGTTAGACCAGAAT
+GATGGCTTTTTTGGAAATTTGAATTGGAAAGGGGTTTTTGAAAATTGGTT
+GGAAGCATTTCAGATAGATTTACATTGAAAAAAATTAGCAGGAGCACCTT
+TTCCATTTTAAAAAAATTTGTTGGCTTTAACTTTTTTCACGGATTTCCGG
+CTTCCCTCATAAATTGAAATGGAAGAGTTTTTGCCGAACTAGGCCATTTT
+GGCTCAGCCATATCTGGGGTAGATTTACGGCGCGTTGCGTGTCGCGTCGC
+GGCTCGTTTTTAGTTGTAAAACTAAATTTATTTGTCCGTGTGGAGTACAC
+AACTTTCCCACGCGTTGTCCATCTGAAGATTGTCAATGGAGCGCGAAAAA
+TTCAGTGAGGAAGGCAAGAACTCCGTTTTTTTTCAATACTGAAAAGTCTA
+ATATTGAATTAATAAATTATTCAAACATTTAAAAACAATCATTTTTAGTG
+TTTTGAATTTTTTTTTAATTTCAAATTTTTCTTTAAAACATTAAAATTTT
+AAAAACATTTCCAAATTGTTCCAAATAACATTATTGAACTCGTAAAACAA
+ATTTAAAGGTGAATTTTCATTTATTTCGTTAAAAAATTACCTTTTAAAAT
+TTATTTTTTCAAAAAAATCTGGATTTTTTTTCTGCGATAATATTCGAGCA
+GTTTTTTTCGATTTTTTTTCTGAAATTCTGTGAAATTATTAACATTATTT
+GAATTAATTATTCAAACAATTTCAAACAGAAATACAACGAGTTTTTCCAT
+TTTTTATCATTTTCCAAAGTTTCAGAAAAAAATTTCGCAAAAAAAATTTA
+GATTTTTCCAAAAAAATTAAATTTTTGAAAAATTCTCAAACGCACGGATT
+TCTGGCTTCCTTCATAAATTGAAATGGAAGAGTTTGCCGAACTAGGCCAC
+TTTGGCTCTGCCATATCTGGGGTAGATTTACGGTGCGTTGCGTGTCGCGT
+CGCGGCTCGATTTTAGTTGTAAAACTGAATGTATTTGTCCGTGTGGAGTA
+TACGACTTCCCCTCCGACAGGCGATTATCAATGAAGCGCGAAAAATTCAG
+TGAAGAAGGCCAGAACCCAAAGTTTCACCGAAAAATTCGAAATAAAAAAT
+CCTGAAAAATTTTTTAATTTTTCCATAAAAATTAAAAATTTTTAAAAAAT
+TCCCAAATTGTTCCCAAGACACATTTCAGAGCAGGTTTCAAAAAATCATA
+TAAATTATTTATAAGGGTAACAACACAAAATTTGGGTAACAAGAGCAACA
+ATTTTTAATTAAATGTTTCATTTTTCATCAAAATTACTCAATTTTCCTGT
+TTCAGCAATCGGCCTATGGTATTTGCCTCCTGGTTCTTCTTCTAGCAGCT
+CTTCCAAGAATTGTTGTAGTACTTGCGTCTCCACAAGCGGCTCCGTTGAT
+TCCTATTCTGTTTTATCTTGTTGGCACCGCGCTCAATTTTTTTCATGTGA
+GTACTTGCTCACTTTTTTATGGTCTAAAAATTGGCGGGAAATTCAAAAAG
+TTAAGAGTTTCAAAAAGATCGGCATAAAATTTAAATTGAACATTTTTGGG
+GATTTTTTTGGAAAAAAAAACAAATTCGAAATTCGACCCATTTTGGCGGG
+AATTCAAATTCTTTTAAAAATTTCGAAAAACATTTTTCTGCAAAAAAAAA
+TTTTCATTTAAAAAAAAAACATTTTAAAAAGCAAGCTTTGCCGGGAAGAA
+TTCAAAAAATGTGGCTGGGATTTTGGCGCGAAATTCAAATTATTTTAAAA
+AATTTTTGAGAATTTCTTGAAAAAAAAACTGAAAATAATTTTGCGGAAAT
+TTGAATTCTTTAAAAAATGCCAAAAAAAAAAGATGTTTGTGCAGAAAAAA
+TTTTAATTTTTAAAAAGCAATTTTTCACGGATTTCTGGCTTCCCTCATAA
+ATTGAAATGGAAGAGTCTGCCGAACTAGGCCATTTTGGCTCTGCCATATC
+TGGGGTAGATTTACGGCGCGTTGCGTGTCGCGTCGCGGCTAGATTTCAGT
+TGTAAAACTAAATATATTTGTCCGTGTGGAGTACACGACTTTCCCTCCGA
+CAGGCGATTATCAATGAAGCGCGAAAAATGCGAAGAGGAATCTGTTCTAA
+AATTAGGCGGGAAATTCAAAAAGTTCAGGGTTTCAAAAAGATCGGCGAGT
+TTCAAAAATGTCAAAAATATTTTTCTGCAGAAAAATTGTCGACTTTTTAA
+TAAACTTTGCCGGAAAGAACACGTGGTGTCAGAGTGTCCGGTTTGATCTA
+CGTAGATCTACAAAAAATGCGGGAGTTGAGAAGCAGAGTTTTCAACTGAT
+TTCGAATGGTTAAGAACGTGCTGACGTCACATTTTTTGGGCGAAAAATTC
+CCGCATTTTTCGTAGATCAAACTGTAATAGGACAGCCTGACACCAAGTGG
+AAGAATTCAAAAAATGTCGCTGGAATTTTGGCGCCAAATTCAAATTACCA
+AACGGTATTTAATACATAGAGCTTCTCACTCAACATCTGAGCTACCGGAA
+ATTAACAACCTTCACATTTTTTGGTCATTACTCACACACATGTGGTTTCT
+AAGCAAGTTTCAGATACTTTTTTTTTTGTTTTTTTTTGAATTAATACTAT
+TTTTTGCAAAAGTCGCTTCGGGACCCAAAAAAAAAATTCAAATTCTTTTC
+AGTTATACGTGTACTGGCACTGGTATTGGCACGTGAGTGCCATGTGGAAT
+TCGGTGGTCCGTGTAAAGTTCGGACAGCGGCTCGAAAACGCGAATAAGCG
+AAGTCGACGGGATAAGCCGATTGTGCCGAAGGAGGAGATCGATGATGCCG
+TTTTGCATTACGTGCCAGCGAATAAGCCAACTGAACAGCAGAATCATGTT
+CAGCACAATCATATCAGTCAAAACGGGATTCAGCAACCAAAGGTAGGTCT
+ACCTACCTGCCTATTTTCCTGCCTACTCGCCTAAGTTTGTCTAAAATCCA
+ACTGCTTGTCTGTTCTGCATACCAATATGCCTAGACATACCCACATTTCT
+GCTCATCTTCTAACATGCCTGCTCGCCTAACTTAATGCTGTATGCCTATG
+TACTAGGTTACTGCCAGCCTGCCTACTTGCCTACCTACACAAATGCCTAT
+CTGACTACATCTATATCTATGCTTCTCTATGCATAAATGCCTGCCAAAAT
+GGCTAACTGCGTGTCAAAGTTCATGCATGCCTGCCTACCTGCCTACGTGC
+GTACATGCCTATTTGCTTACCTAAATGATTACCTGCTTACCTACCTGTCT
+ACCTGCTTAAGAGCCCTACTTATTTGCCTACCCACCTGACTGCGTGTCTC
+CTCTCTTTCTGCCAATCTAGGCCTACATGTCTATCTAGGCCTATATAAAT
+TCCTACCTGCCTACCTGCCTAAATACCTACTTGCCTGGCTATGTCTTCTT
+ACCAACCGTTTTTTTATGCCTACGTACCTGCGCGCATGCCTACCTACGTG
+CCTACCAACACCTACAAATACCTGTCCGCCTTCATCACATTTTTCACTTT
+CAGGTAATCCTTCCACCACCGAACCCCTACAACACCGCGCCCACACATTA
+TCGACGCCGATCCTCCACAGAAGCCCACCGCTACCACCCACCTCGGCAAC
+CGAGAAGCTCGGCGCCAACCCACCACCGAGTACCGGCCGACTATCCGAGT
+GACGAGGAAGACGACTATGATGATACGGAAGGAGACGACGCGGATATTGA
+TGATCTACCCACACCGCCACCGCCGATTTACGCCGTCCGCCTGACCTCCG
+ATTCGTGGGAGAATCAGATGAGCCGCCCGTCGGGTAGACGGCGGTTACCG
+GCGACTCCGAATTTGCCGAAACATGGAGAATTGCCGCAGATATTTAATAT
+TCCTCATGCTAATGTTTAATCAAATTTTTGGGGTTTTATGGGTTTTGGAT
+TTTCGGAGCGGAGCTTCATTTATCGCTTTAATATTGAATCAGGGGTGGTT
+TTCAATTCTGGCAATTTGCCGGTTTGCCGATTTGCCGGAAAATTTAATTT
+TCGGCAAATTGCCGATTTGCTGTTTGCGGGATATCAGATTTTCCGAAAAT
+GTTTAGAGGGATTTTTTATAAGACGAAAACACTAAAAACTGTGTCTTTTT
+GAATTTTTTCCACTTTTTCTACATATTTTCATAGAATTTGCTTACTTTTC
+AAATTGCCGATTTGCCGGAAATTTTTAATTCCGCCAATTTGCCGATTTGC
+CGTAAAAAATCGTTTGCCGCCCACCCCTGTATTGAATTATCCGGAACACA
+GCAACACTCTGAAATTCGAGCATTAGTTAAATGTGATATTTGAAAAGTTT
+TGCAAACAAAATAATTTTCCCCAGCTTTCATCATTTTTTCTTTCAACAAA
+AAAAAACCGAGTGATATTATGATTTCCAATTTGTGCTATTTTGAGTTTTA
+TTTTATTTTATTTTGTTGTTTTCAATAAATAAACGAATATTTTTTGGTCA
+TTTTTTGGCGCTATGAAACTAAAAAATTTCAGGTAACTTAGCGGGAAGTT
+CGTTTTTTTTTCATTTTGGCAGGAAATTTCATTTTATAAAATGGCAAAAA
+CTTTTCGTTAAAAGTTTTTAAATTTTGAGAAAATTGACGAGAAATTAAAA
+ATTTCAAATTTTTTGGCTCTAAATTAGGATTATAATTTTCCGAAAAAAAA
+TTTCCGAATTAAAATTTGGCGTCTCAGTGTGTTATTCAATTAGAAAAACC
+TTCAAAATATTAAGACATTTCGGAGGCACGTGGTGTCAGAGTGTCTATGC
+TCCTTTAAATGATGCATTCAAAGGCGCTTACACACCTGCACGTAATCTCT
+TTTTTGTCTCAAAACAAAAGGAGCTTCAGACTCTCATATCTCTGCAACTC
+TGTGTGAATAACAATTGGAGCCCCAGAGCTCCCGGCTCCACACTGCCCGT
+TTCCATGGAGACACTCCGATTATTATGGGAGCCACCACTGCTCGCCGAGC
+AGCAGCAGCAGCAGCCCATTGTTAACCCGATGACCAATATCTATATTTGG
+GTCCGGACCGCCCGTTCCCTTCAGTTTTTTTATCCGACTATCGATGTGGA
+GGCCGATGGGTTCGGTTGCTTCTATGAGATTTGTTTGGAAATTGTTGGCT
+TGTTGGAGGAGTGCGATAGGATAAGGTAAGCGTGCTCTATTGATAACACG
+AATTTTTGTGATTTTCGGCAACATGGGATCGTGGTTGCCCAAAGGGAAGG
+AAACGCGCCCCATTGATAAAATCATTTCGCAATAGAGCGCATTTTCATCA
+TTTTTTTGCAGTTTTGACGAATTCGAGACCCTCTGCGAGAATAGAATATC
+GGAAGTTTATGTGGAAGCAATTTTTCAAAATGCTGTGGAACAAGGAAATG
+TGAGTTTTTTTGTGATTCTGATGCTAATTTAGCAAGTGCGCTCTATCGAC
+AATTATGACTTTGTGCACGTTCAAGTATTTTCTCAAAGTTTAACACAGGG
+TTCTGGCCTTCCTCATTGAATTTTTCGCGCTCCGTTGACAACGGACAACG
+CGTGGGAAAGTCGTGTACTCCACACGGACAAATCACATTTAGTTTTACAA
+CTAAAATCGAGCCGCGACGCGACACGCAAGGCACCGTAAATCTACCCCAG
+ATATGGCCTGGCCTAGTTCGGCAAAAACTCTTCCATTTCAATTTATGAGG
+GAAGCCAGAAATCCGTGAAGTTTAACAAATTGTGAGGTGTAGCAAACACG
+CTCAAGTGACAATTTTTACTTTATGCGTCATAAATTTTTTTCTGAAACTT
+AGAAAACGCGCTCTATTGCTACTTTGAACGGAAAACGCGCTCTAATGTCA
+ATTTTATTTCCAGATAAACGCCCGCCTAAAGCTTCTCACCTTCTCACTTC
+TCTTCGCAGGTCTCCAACAAAAAACTAAAGATCTCACAAATTCCATCAGG
+TCGGACGTGGTCTTGACACGAATTTCAAAGTATTTTGGTAAATTTGAAGA
+ATAATATTTGTTATTTTTTTGTTTTCCGAACTTTACAGGCCAAATATTCA
+AACTTTTGTTCCAATTAGACGTGGGCCGCCGGTTACAGGACAGAGAAATT
+GTGCACGCCATTGGAAATGGGCAGGTGAGAAGTTCGGCTACAAAAACGTG
+ACGCGTGGCCTAGAAAGATTTGTTTTTCCACAGCTTTTTCCACAGCTTCC
+ACAGCTAACGGGATGGCCTAAAAAACTCCACGGTCGTTTAGCGATAGAGC
+GCACTTGCACATTTTGGGAATCTTCTGGAAGAAAGTAAACGTCACAAAAG
+GCCTAGAAATCTTTATCGTGTGTGGTTTAAGAAACAATTCTCGGCTTTGA
+AATTATGGTTGCTCGGGGAAAAATGATTGTTAGAAGCCGCACGCTTGCAC
+GCTTGCACAGCTTGGGAATTTTCTGGAAAAGAAGTGACGTCACTGGTGGC
+CTGTAAATTTTCGCCATGTGTGAATTAACAAAACAATTATGGGCTTTGAA
+ATTATCGATTTTCACGGATTTTTGGCTTCCCTCATAAATTGAAATGGAAG
+AGTTTTTGCCGAACTGGGCCATTTTGGCTCGGCCATATCTGGGGTAGATT
+TACGGCGCGTTGCGTGTCGCGTCGCGGCTCGATTTTAGTTGTAAAACTAA
+ATTTATTTGTCCGTGTGGAGTACACAACTTTCCCACGCGTTGTCCGGCGG
+GCGATTGTCAATGGAGCGCAGAAAATGCAATGAGGAAGGCCAGACCACGT
+GAAAATCAATAAGTTTTTCAGCAAAAAATGAAAAATGAGGAAATTTCGTT
+AATTTTAGTTTTGTTAGCAGTAGTGCGCGCTCACATAGTTCAAGAATTTT
+TTTTTGAAGAAAAGTGACGTCACAGATGGCCTAGGAATCTCATCTATGAC
+GTCACTTCTCTTCCACTTTATCCTATTTTCAGGGCTATGAATTCCTGGAC
+ACCCTATTTGAGGGAACAGTAAAGCACAGACATGGAAACTCGAACCATCA
+CGGCGTGCGCCCCCTTTCCCATATAATCCCCCAAATTCTCGAAAAAGCGA
+GCAGTATATCCCTACCATTTTTGTGCAATGAAATCCGCCGACACCTTATC
+AAAGACCCGTATCATATTGATGAGTTCTCAACTGACAAACCTGCTCAAAT
+ATTTTCGACGGCTCGCCGAACGACACTGGCACATAATAGTCGACGGGTGG
+TACACTTGCATTATATCAATCGAATTGAAGTGCTGCGGAAGGATGAATTT
+GCGAATGTTCACCTGAGAATTTGTAATGATAAGATTAAGGCGTCGTTCGT
+TTTTGTTCCGTTGAGGTGAGATTTTTTGGCCGAACTTTTTTTTGTTGCTT
+TTTTTGAAAAATTTTTAAGAGATTTCATTTTTTTTTACAATAATAGAAAA
+ATCAGAAAAAATATTCACGAAACCAATAAGTGGGCGGAGCATCAAACTGG
+CACGCTCATTTTCCGTAGATCGTTTCTGCCAAAATCGAAAATTTCTTGAG
+CTTTCTTGAAAAATAACGCTAAATTTAATTGTGAATTTATTATTATCTCG
+AAAAAAATTATCAAACAGTCGAAAAGGGGCGGGCTTACATTTTTTAGCCC
+CGCCCACTTTTAGATTTGTTTTGTTGAAAAATGTCCAAAACTGAGTTTTT
+CTCGGAAAATTTGAATTCCCGCCAAATTTTTTTCCAGAAAATTTGAATTC
+CCGCCAAATTTTTTCCAGAAAATTTGAATTCCCTCCAAATGTTTTTATTT
+TCAGAAAATTTGAATTTCCCGTCAAAATTTTTTTCCCAGAAAATTTGAAT
+TTCCCGCCAAAATTTTCCCAGAAAATTTGAATTCCCGCCAAAATGTTTTC
+CAGAAAATTTGAATTCCCGCCAAAAAAAATTTTCTCAGAAAATTTGAGTT
+TCCCGCCAAAAAATTTTTTTTAAAAGAAAATTTAAATTCCCGCCAAAATG
+TTTTCCAGAAAATTTGAATTCCCGCCAAAATTTTTTCCAGAAAATTTGAG
+TTCCCGCCAAAAATTGTTTTACTGAGAAAATTTGAATCCCCCCCCCCCCC
+CCCCCCCCAAAAAATTGTTTTACTCAGAAAATTTGAATTCCCGCCAAAAA
+TGTTTTTTCTAAGAAAATTTTAATTCCCGCCAAATTTTTTTTTAGAGAAA
+ATTTGAATTCCAGCCAAAATGTTTTCCAGAGAATTTGAATTTCCCTCCAA
+ATTTTTTTTTCTCAGAAAATTTGAATTCCCGAATTTTATTTTTGAAAATT
+TGTGTGAAATTAAATTTTTGGGAATATTCATTGTGGCCTAAGTTGCTCCA
+AATGGAAGAGTTTTTTAAAAATTAATTTCTCGTCCACGCGTCAATTGTAT
+GCAAGAAATTCGAATATTTTCCAGATGTGAAACCGTATTCCTCGACAGAC
+TTATGTACACAAAATGGATAGTTCTTGGCGCAGTACGCGGCATTGTAATT
+GTTAAAAATTGTCAATCGACCCGAATTTCGGTGAGCTGCGACCAGCTGAT
+TGTGCTCGATTCGAAAAATATCGAAATCTACGCCATGTCGCCGAAGAAAC
+CAATAATTTTCAACAGCTCTGCGGTAACTTTTGCCCCATTTAACACGATT
+TACGAGGTGAGTTCGGTGGGGCGCGTTTGCATTTATGAATTCGAAAATTT
+>CHROMOSOME_II
+CCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCC
+TAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTA
+AGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAG
+CCTAAGCCTAAGCCTAAGCCTAAAATAGTGACTCTGGCAGTTCTCTAAAA
+TAAGTGACTCTGGCAGTTCACCAAAAATTGTGACTCTGACCGTTCACCAA
+AAATAGTGACTCTGACCGTTCACCAAAAATAGTGACTCTGACCGTTCACA
+AAAAATAGTGACTCTGACCGTTCACCAAATATAGTGACTCTGACCGTTCA
+CCAAAAATTGTGACAATGACCGTTCACCAAAAATTGTGACTCTGACCGTC
+ACTATTTTTATTGAACTGCCAGAGTCACTATTTTTAGTGAACTTCCAGAG
+TCACAATTTTTAGTGAACTGCCAGAGTCACTATTTTTAGTGAACTGCCAG
+AGTCACTTATTTTGGTGCACTGGGGTGGGTCACGCCCCCAGTTCTCAGTT
+ATGGGTACTCTGATCCACTCGGGACCCACTTTATCGTGTTCCCCGTGCCT
+CATTTACCCTAGAGCTTCCTCCTTTACCTCTCCTCTCGCTATCTCTAACA
+TTCCAATGGAAACTCCTATTTGAATTACCGCCACCGATGTGCCCGACGCG
+ACTTACTGTTAGCCCTTGTTTTGCACAAATCTGTTGGCTTCCATATTTAA
+AAGTTAATTAATGACCCAATGTTCTTTTTTTCTCTAAATCTCCACAAGAT
+GTTCTGTTTTCCCTACTGGACACTATCGTTCACTGCGTCTCACCAATTCA
+CATTGTCTCTACTTTACCTTTTTTGTCATAGTACACGTTCGCCAACGGTG
+TCGACGGCCAAATGCTTTGGGCAGCGTTTGCTTTTTTTATAATTAGTTTT
+ATTTTATTAAAACAATAGCTCTAAAGTTTACAAGTCATTTGTTATAGGCT
+AAATGAGTTATGTCTAATAAGTAATTTGAACTAGATACTTCCGTGTAAGT
+GACAATGTATCGGAAAAGTCCTCAAAGTGCGATGTAGAAGTTCACATGTA
+CTTTGTTTGGCATGTTAGTAAAAGAGCCAGTATGCTGATTCATTTTATAT
+TCTATATACTCATGTAATATGCCCATGTAAGGTTTAATTCCAAAAATATG
+AGCGTGTTCTATTTTATAATATTTTACTAAAATACCTTTCAGTTAATTGC
+ACTCAAATTTGTTGTTCTTCATTCTCTCGTTATGATTTAATCTTATTGCG
+TCAAGGTCATTATTTTAGGTCCATTAGTTATCGATCTGAAACATGTTGTT
+GTATTTTTCTATTCTTGTGAGCTCAGGACACCTCATACAACTCCAGAGAA
+AATGTGTCTCATTATTCTTGTCTTTTTTCAAGATCTAATCAATTTTCTAC
+ATTAACGACGTTTTTGTCGTTCTGCTTCTTTTTTTCGTTCGTTTGTCTCG
+TCCATCAGCTGTCCACTCATTTCTCTCCCACTCACTAGGCAGTGCTTTGT
+TTGGTTCCGATTGGCAGCTGGCTGCAGGGCCTGCATCTCTTCTATGTCTC
+TCATTTACTTGCATTCTTTTCTTCGTTAATTTTTGTTATGATATTTAAAC
+GGGAAGAAGAGTTTGTGGTTCTTCTTTTTATAATCACTAAAACTTTTGGA
+TAAGTAACAATTTTCTGATAAAAATATTTTCACGGCGAAGAAAAAAGAAA
+AAGAAGAGTAGTTTTTGCACGTTTTCATATAATTATTTTCGTTGATCAAA
+TGTTCTTCTGGAGTTTTCTAATAAATTTCTTATCGACTTTTTTTCAGAAA
+TTTTTCTCAACTTGTCATGTCAATGGTAAGAAATGTATCAAATCAGAGCG
+AAAAATTGGAAGTAAGTTCTTTATAATTTCATTTATATACTATAAGTTTT
+CTCGATCACAGGAGAAACAAAAACAACAGACAACACAAAAAACAATAAAA
+CAATATTGCTCTAGTAATCAATAGTGTTGTAAAGAGGGAAGAAAATTGTT
+ATCTGTGTAGCAGTCAACGTTGATTGAGATGTTGTGTTTGACTATAGAGT
+TGAAAATAATAACTTCAAACTTGCAAGTCATGACTTATCAAACACTGCCG
+GAACTTATTCTGGATCAAAGGAAAGTTGTCCAACTGTAGAGTCATGTTTT
+TCAAAAGAAAACACAATTTTTAAGTATAAATATTTTGAAAAAGTATGTTT
+TAGAAGTATGTCAAATTAAAAAAAAAATCCTTGGTTAAAAAATGATTTTT
+TTGGATATATGTGTATTTTTAACTAAAAATATATACTTTACATATATATT
+TTGGCGCAGTTATTTGATCTATAAATCAAACTTTTTGATAGACATTTTTT
+TATATTTACAACAACTAGGGTTGTTATGAAAACGCCTATTATTCTACAAA
+CTAAATTATTTTAATCATACATTCCCCACTATCTAAAAACTAATGCAATT
+TTCAGATTTTGTCATGTAAATGGGTAGGATGTCTCAAATCAACAGAAGTG
+TTCAAAACGGTTGAAAAGTTATTAGATCATGTTACGGCTGATCATATTCC
+AGAAGTTATTGTAAACGATGACGGGTCGGAGGAAGTCGTTTGTCAGTGGG
+ATTGCTGCGAAATGGGTGCCAGTCGTGGAAATCTTCAAAAAAAGGTATTT
+TTAATTTAATGTGCATTTTATAATATAAATTCTTCAGAAAGAGTGGATGG
+AGAATCACTTCAAAACACGTCATGTTCGCAAAGCAAAAATATTCAAATGC
+TTAATTGAGGATTGCCCTGTGGTAAAGTCAAGTAGTCAGGAAATTGAAAC
+CCATCTCAGAATAAGTCATCCAATAAATCCGAAAAAAGGTATTCACAATT
+TGCATGATATTGTTATAATCTAATTTTCAGAGAGACTGAAAGAGTTTAAA
+AGTTCTACCGACCACATCGAACCTACTCAAGCTAATAGAGTATGGACAAT
+TGTGAACGGAGAGGTTCAATGGAAGACTCCACCGCGGTAAGTGTGTTTCT
+TTAAAAATTACTTCCTTTTTTCAATTGTTTGAAATTAACAAGAAACCTGT
+TGGAGCGTATTTCTGAACTTTTAAATCGAAAATATCATTTGCAAAAAAAC
+TTGAAAATTGAGAAACTTTTTTAAAAGTGGAGTAGCGTCTGCGGGTTTTT
+TTGCCCTAAATGACAGAATACATACCCAATATACCGAATATAACCGTAAT
+AAAATTATGCGATTTTTATTTTTATTTTTCATGAATGTTAGGGGCAAAAA
+ACCCACATGCGCTACTCCGCCTTAAGAAGAATCAGCTGTGAGCACTATCC
+ACTATACATTGGAAATTTACAAATAAAATAGAGATTAAGTAATATAATTT
+TTAAGGGTTAAAAAAAAGACTGTGATATACTATGATGATGGGCCGAGGTA
+TGTATTTCCAACGGGATGTGCGAGATGCAACTATGATAGTGACGAATCAG
+AACTGGAATCAGATGAGTTTTGGTCAGCCACAGAGATGTCAGATAATGAA
+GAGTACGTTGTTTTGCAAATTGATTAAAAGTGGAGTAGCGTCAGTTAAAA
+ACTCTAACATGTCTTAGGTTTTTCAAAAGTTTGGTCAAAGTTTTGGCAAA
+CTGCCAACTTCTTGAAAACTTCGTTAAAAAAATTCTTGAAATGATTTGAA
+AATTTGTATTATGTTATTCTCTTATTTCTGCACTATTCTATATGGCGCTA
+CTATACTTTTAATTGATTTCTTGAAAGCAGTTCAATAATAATTAATTTTA
+GAGTATATGTGAACTTCCGTGGAATGAACTGTATCTCAACAGGAAAGTCG
+GCCAGTATGGTCCCGAGCAAACGAAGAAATTGGCCAAAAAGAGTGAAGAA
+AAGGCTATCGACACAAAGAAACAATCAGAAAACTATTCGACCACCAGAGC
+TGAATAAAAATAATATAGAGATAAAAGATATGAAGTAAGTCGAAATTGAC
+AAACAGTGGTTTTTGTTTAAGTTTATTGCGAAATATTCAAAATTAGACAT
+GTTAAAATTTTGCGAGATAATCTAAAGATTAGGTATACAGATTTTTTCAT
+GTAAAGTTACATTCATCAAAATTTTTGTGTTCACCAAATTAGACAAAAAA
+TGTTAGTTACACAGTATATTTATTTTTTATATCAATAAAACCTTTTTCAG
+CTCAAATAACCTTGAAGAACGCAACAGAGAAGAATGCATTCAGCCTGTTT
+CTGTTGAAAAGAACATCCTGCATTTTGAAAAATTCAAATCAAATCAAATT
+TGCATTGTTCGGGAAAACAATAAATTTAGAGAAGGAACGAGAAGACGCAG
+AAAGAATTCTGGTGAATCGGAAGACTTGAAAATTCATGAAAACTTTACTG
+AAAAACGAAGACCCATTCGATCATGCAAACAAAATATAAGTTTCTATGAA
+ATGGACGGGGATATAGAAGAATTTGAAGTGTTTTTCGATACTCCCACAAA
+AAGCAAAAAAGTACTTCTGGATATCTACAGTGCGAAGAAAATGCCAAAAA
+TTGAGGTTGAAGATTCATTAGTTAATAAGTTTCATTCAAAACGTCCATCA
+AGAGCATGTCGAGTTCTTGGAAGTATGGAAGAAGTACCATTTGATGTGGA
+AATAGGATATTGATTTTATAACGTGTAATTGAGTTTTGGCCAAAAAGGTA
+TGGAAAGGTGGCTGTTTAGTTATATATTTTTCTATTATTTATTTGAAACA
+TGCAAAATTGAAGTGAACAATAAGTGATGTTCATGGAAATTTAAACTGTT
+TTATGATACTTTTTTGAGAAATTGAAAAATCTGTTCATTTTAGAAACAAT
+GTCCACATGGTTCTAAGAGCTAAAATTTTTATTTTCATCCATTTAGAGTA
+CTTTCTCTTTTAGAGTACGGCCCCAGAGCGATGTTAGAAACCTGAGATCG
+GTCAACACAGACCGTTAATTTTGGGAAGTTGAGAAATTCGCTAGTTTCTG
+>CHROMOSOME_III
+CCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCC
+TAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTA
+AGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAAAGCGCGAAATCCTATGAA
+ATTTCAAGGATTTATAACTTTTTGAGTCCGAAAAGAGTCGGAAATCAGAT
+AAAAATAAAATCGGGCTTTTCGACCAAAATTAGGCCTCGAAAAGTCTGAG
+AAAGCACGGAATCTATGGATTCACGGCTTTTTGATTCCGAAAAGGTTCGG
+AAAGAGAAGAAAATCGATAAGAATCGATAAATTTGCAGAAGTATTGCAAA
+TAAATTCCGATTTTCACTAGAATTGCGTCATTTGGGCGCAGAAAATCGGG
+CTTTTCGACCAAAATTAGGCCTAGAAAAGCATGAAAGGGGTCCAAATTCT
+GAGATTTCGCAACAGTTTTTGGACAAGGTTATCCCGGAAATTAGCGGGAA
+GCACTGAAGATCGAAAAACTGAAGATCTTGTCGTTGAGAATCGTTCAACA
+GCGTCAGTTACTACTGAAAAACTGATTTTTGAGCAGAAAATCTGCCGAAA
+TGTCCGAAATCGGACGAAAATCAGTGGTTTTTTCGCCAGGAACTCGTAAA
+CGAGCGGGAAAAAACACTAAAATAAAATACATAATCGACGACGGCGTCGA
+AAAATGGACTTTGGAGGCGATTTTGAGATAAAAATCGCCTCTCTGAGACC
+GCGTCACCGCAACTCGTGCCTCCATCTGACTCAGGATCCGAATCCGGCTA
+ACGAGTATACTCGAGCCGGTTCGGTCGATGCACCAATGTTGACACCCATG
+TTCTTCGGGGAGTCAGACCCGATAGGTAACAAACGTGCGGCTTACTTAAT
+GACGCGCGGAGGATACGGAGCTAGTACGAGCGGTGCGACTGATGATGCAT
+AGGGAATAACAGTACACAAGCTTGAATTAATCCAAGTTTATTATCGAATA
+AAAGGATTAATCAAAGAAAAAAGGAGGAAAGGGCGAGCTGCATTGGGAGA
+CGACCTTCCTCGACGAGAGTTGTTGAAGAATTGAATGGATCGTAGGCCAG
+AGGCCTATAATAATTATTGTGTGGATTTACGGGCAACGACACTCCGGAGT
+AACGCTAGTTAGCGAAGGAGCGCGGTTGCATCTGAATAGCGCATATTGGC
+ACGTAATTCAAATTAGAAAAATTACTAAAATGATTTAATTAATATTTTTA
+ATAGAACGAATGGAATATAATCAGCAAATGGTACAAGCGGACGTCACAAC
+ACATTGCTTAATAATAAATTTCCAACTGAAACCAATAGATTCAGCCTTGA
+CACAACTGATCAGAAACTTGTTATACATGTTAAAATACTCGAATTCATAT
+TCATCGCCACCAGAATAATTGGGTTTGAACACTCTTGCAACTTCAACTGA
+GATGGTACCGTAGATCCAGAAGATGCATTGTTGGAATGTACTTCTTCCCA
+AAAGGTTCTGAGATTTAATTGATTTTTAACCTGGGCCTAAAAGTCTCACT
+TACGTACATTTCTAATATTTAAGGCATTTAGTGCTGAGAAGTATTCGACA
+GTGGCCTCGATGTTTTCAAAGTGGAATAAATAGTGAATTGGAATAATGTT
+GAAATAATGACCAAAAACTTTACATTCTTTTGATTTTTTCCACTGATCCA
+TCCGAGTAAGCTGCTCAAAGTCATCGATTGTTTCAAGGCACCACAATTCA
+ATACTTTTCAACTCTTGAGAATCGAAATAGGGCAGCGTAGATATAATATC
+ATTGGGTGACACAAAAATAATCGATAATTCCTTCACATGAATGCATTGCT
+TAGATCTGAGGATGTTCAGAAAATATGTGGTAACGTTAAGGTCTTGTTGA
+GTTTGTACAACAAATTCGAATTTCCTGACACGTCCCAGTAATATTCTCAA
+ATCGTTGAAAGCTAGTTGCATGAAGTTATCTCTTCTGATTACTCTCTTTC
+TTCTGTGAGCCACAATCGAATTCCCGGCATTGGTGTAAATGATTTTCATT
+TTATCAATCCGCATTTCAACTCGACCATTGCATACCCAAAACGAGATAGA
+ATCAAAATTAATTCCATTTTGAACAACGGCAGCTCTCAGACTTTTACAAA
+TTTTGAGGTGAGTGAGTCTGAAGAATAATAGCTTGGTTATGATTTTTCAA
+AGTTAGGGTACCGAAATCTTGGAAATATTTTTAATTGACTCCAAATTTTC
+CCCTGATTCCGAAAATCGATGTGAAAAAAATCAAAAAAAAAATTCCTGAT
+TTTATATTTAAGCTTGAAATCACGCATTTCATTTGCGCCCCGGTCTCTTT
+TTCAAATTCGCGCCCTAATAAATTTGCATTGGAGCGCACTTGCATCGTGT
+CATTTTCTTCGTTTTTTTCATTTATTTTAGCAGAATTCAATGTTTTAAAC
+CAGTTTTATTCATTTGTGGAGAGTTTTTATCGGTTTTTTTTTGACTAAAA
+TGAAAAAAGGGTCCAAATGAAAATCGAGATGAGCTAAGTCAAGCTTAAAT
+ATAAACCAGGGAAATTTTTTGATTTTTTTTTTCACTTTGATATTCGGAAT
+CATGGGAAAGTTGGGAGTCAATTAAAAATATTTCCCAGATTTTGGTACCC
+CACCTTTAAATCAAAATAAAATCAACTAACTGATCCACTGGCTTTAGCTT
+TTCCAATACTTGACCAAGGATCTCTGTGGGCATATCGGAAAGAGTAGGGG
+AAATGTGATCCTGGCTGTAACAATCAAATTGCCATTAACCCAGTATTTCA
+ACAAAAAAAAACTCACAAATTCATATATCGCACAAAATTAATTGCCCACC
+ATTTGTCAAGTTCAGCTCCACGTTCTTCAGTCAGAGCACGTCGGGCTTCT
+CGGCTGATTGTTACCATTTTCAAAAGATATAATTTCTTTAACACAGAAGT
+TAAATAAAATATGTCCGATAGCAAAAAGTAGATGTGAATGAATTGAAGAA
+GAACTGAGAAATAGCTAAATATCTATGTCTTAATTTTCATAGAGTTTCAT
+TGTCAGATACTACAATGTTACTATTGAGAAAAATGTCAAACTGATAAGAA
+TAGCAGCCAGCTTAAAATGAAAATTTGATAAGAAATTGCTGTCTTAATAT
+TAATTATATTGTCGTCAACAAACAGAATTTTCACTTGCTAGTTGTTAGTT
+TAAATTATATTTTGATACCGAAAAGTGTTTGAAAATGGGGGGAAACTAGA
+AAATAAAGTTTTCTACATATTCCATATTTTCAGAATTGATTTCAAGATAT
+GTCGGAAACAAGCCAAGAAGCTCGACGTGCACTGACGGAAGAACGGGGAA
+AGGTGCTTGACAAATGGTGGGCAATTAATAATTTGAGATTCATGAAATTG
+TGAGTTTTTTGGAAATACTGGCTTATTGGCAATTTGATCGTTACAGTCAG
+GATCCCATCTCCCCCACGCTTTCCGATATGCCCTCAGAGATTCTTGTTCA
+AGTTTTTGAAAAATTTGATTCTATAGAACATTAAGTTGCTTTGACTTTTA
+CAACAAAAATATTCGGTATAAAAATGTTCTGACTTATTTGTCGAAAAGTT
+TGTCGAAGTCTGAAGCCCGCCGTGGAAAAAATTGAAATTCATTTTGATTC
+TATTTCGTTTGAAGTATTTAATAAAAATGTTATTATGAAATTGGATGGAT
+TAAAAATTCTCTACAATGATGTCGCAAATGGTGCTTCTATAGTGGCTTAC
+AATAACAAGGAAGCAATGATCAAAGGAGAAAACTTCCTGAAACTAGCTTT
+CAATGATTTGGGAATACTACTGGAACGTGTGAGGAAATTCAAATTTAAAA
+TCTATGGAGACGATGTACATGCCATTGCCACATTTCTTTTAAATGCTCTC
+AAAGCTGATCAGTGTGTTCACGTAAAGAAAGTAGTGCTTTTTTACGTGCC
+ACTCATTGATATTTGCTCAATTCTCTCGTATTTTGATTCTGAAATGTTGG
+AAAGAATTGACTTGCGTTGTAATGATACAAACGCTCATTTTGAACAACTT
+GCTCAAAAAAAATTCCAACGAACAAAATGTGTAGAACTTTACAAACTTTT
+TAATAAAGATTTCCAAATTTTTATACAGATTCACTAAATTTCCAGAGTTT
+TCCCACAAACCGACACACAGACCGACCTGGTAGTGGAGAGGACAACATCT
+TTATTCAATCCAGTCAGTGAAGTGGAATTAAACTGGGCTTCAAGGAAGAA
+ATGGCACAACGGAAAAGGTCGGGAGAAAAACCAAAAGTCGGAAAAATATT
+TTTTATTGAGATATAATTTTTTTTGGTAGAAACATTTTTCTTCGAATTTA
+AATTATATTTCGCGCCAAAAATAAGATTAAAAACCAAAAAAAAATCCGAG
+TGTGGAGAAGTATTTTCGAAAATATTCCTCTAATAATACCCTTTAACAAG
+GGCTATAATAATGGAATTTCGGGTGCTTGAAAATGAGTTTTTTGAGATTA
+GAAGTATGAATTTTTGTGTCTGGTGTTAAGTTATTTAAGTTATATTGAAT
+GGAAATTTTAAAAAAATTCTGAAAAAATATTTATAATTGTTATTTGAAGC
+TACTATTTCACCTGGAAACTTCTAGAATTTCCAATTTTTTTAAAAATTTT
+TTAAAAATTTTTTTATTTTCAATATTTTTCACATATGATACAATTTATTA
+TGAGATTTTCGGAATTTTTTAAGTGAAGTTTTTCCCTAAAGTTTTCAAAA
+TTGACTCGAATTTTCTGGAATTTTTTTTTTCAAAAGAAACACAGCTTTTG
+TTTAATTTCCAGTTAATTTTTAGCTTTAACATTAAAAAAAATTTCTTTCA
+TTTTTAACAAAAATTCCCCTTCTTATTTTAGAATTCAAAGCCAAAAACCT
+TCAAATTCAATTTTATCTAAAACCTCCTCAAATTCGAAAAAGTGTGAGAG
+AGATACGCGAGCTACGAAAAAGAGCAAAAATCTGAGTTTTTGAGCACTTC
+>CHROMOSOME_IV
+CCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCC
+TAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTA
+AGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAG
+AAGAGACCAAACCGAAAAATCAATTTTTTAAACGAAAAATCAATGTTTTA
+AACGAAAAATCTATTTTTTAAACGAAAAATCAATTTTTTAAACGAAAAAT
+CCATAAAAAATTGTTATAAAAATTCTGGAAAAAAAACTAAAAACTTAATT
+TTTGCTTTGAACATTCATCTTTCGCGAAAAAAATTTCAGCAAATAAAACC
+GAAAAATACAATTTTGCAAATAAAAAATCTAAATCAACAGTAAAAAACAA
+AAAAGTCAAATTTCAATAGAAAAAAAAATCAAAAATCAATTTTTACTCCA
+AAAATTCAACTTTTGCCAAAAACTAACCCAGAAAAATCAATTCACAAAAA
+AAAACAAATAAAACTGCAACGATGTTTGTGAAAAAAATTTTCTTGATATT
+TTTAACGAATTTTTGTTTAAAAAAAATGCATTTTTGGCCATAAAATTTTT
+TTTTTGATTTTTTCAAACGAATTTCCCCTCAATTTTCTTGCAGATCGACG
+TGGATATTGACGACCTAGATGACGATTTTCTCTCCACAAACGGAATGGAA
+CGACACGGTTCAGAATTACAAGGAGAAGTGGTTTTCACTACGACGAGTAC
+TGCGAATAACAATGTGAAACGAGCCGTCGAATATTTCGAAGATGATAATC
+AAGATGATGCACTAACATCCACTTCATCCGGCAACAGTACACAGAAGGAA
+TCGTCTCCGTTCACAGATTTTGATGATGTTCCGCCGCCACCAGTGGCTCC
+AGAAACTCCGGCTCCAGCCCAAAACCGCCGAGAATCTGCGTCCCCCGAAC
+GTCAATTCCTTGATGAGAGTCACCTCGGCGGAATTGGATCTCCGTTATCA
+CAGAGTACAAGGCTCGATGAGACGTTTATTGAGGAATACTCTATTGAGTT
+GGACACCTCTGGGAAGTATGTGTTGGGAAAAAAAATCCGAAAATTGATTG
+AAAAATTCGAAAAAAAATCCAAAAAACCTTTTTTTAATGAGATTTTTTCT
+GTGCAAAAATTTAAATTTAGAGCTGAAGAATGTGCACTTCTAGAAAAACT
+TATTTTAAAAAATTCACATCCTTTTATCAAATTTATTAGCATATTTATAC
+AAATTGATGGATAAAAATTCCAAAAAAGTTCCAGAAACAACATTTCCTCC
+GCAGCTTCACCTGGTCCCAAGTCTCCATTTGACGATGATTTTACTGATAC
+AGCTGCCCCGGTAGCCCCGCCACCAGCACCTACAAAAGCTGCCGAGGAAT
+ATCGCCGGCAACCACATCAGAATCCGTTTGATGAGGAAGAGGAAGAAGAA
+TCACAGTTTGGAGGGGGAACTCTGTCCGGTAGAGACCCATTTGATGAAGA
+TGTACGTTTTTCGTAAAGTTCGGAATTTTTAGGGTATAAATTGAAAAACA
+AATGGAGAAAATATGAATACCTAGATTTTTTTTTTCAAAAAATCCCAACC
+CTAATATCCACAATTTTTTTTCAGTCTGGAAACTCTAACGAAAACCAGCT
+CCGCGAGAAGAAGCTCCACAAAAAAGAGCAACTAGCTCACCGGCTCTCCT
+CCTCTTCCGAAGAAATTGTGGAAGCCTCAATTCACGAGGATGAGCCAATT
+GTGATGGCTCAAATTCCAGAGGAGAAGCCCAAACCGAAGGCTATCCCGGC
+TTTTGATAACGCCTATGACGCCGACTTTGACAATTCCCCACCACTTCATC
+ATTACTCGGCGGTTCATTTGGAAACTGGGCTCTCACCGCTTGAGGAGGCT
+CAGAGAGCTCTCCGAGCCAACCGAGCAAGGCATAAGCCGTCGAATGTATC
+GTTGGCAGAGGAGGCGAAGCTTGCTGCCAGACAGAGATACTCGAATGCAT
+CGGATATTAGAAGAGAAGAGGAGGAAGAAGTGGTGGAAGAAGATCCAGCA
+GTGGTAGTTCCAGTTCTACGGAAGGATCTGGAAGTTGAGGAGGCTCCGAA
+ATCGGTACGACCGCCTAGATATCGGAAGTCAAGGGAAATTGAGGAACCGG
+TGGTTGTTGATCGGTTTGTTGAGGAAGAAGTTGATGAGAAGGAGGATATT
+GATGCGATTTTTGAGAAATATCGAAAGGTTCGTAAAGATATTTTCGAGAA
+AAACGGCGTTGAAAATTTGAAAAATTTGAACTTTTTTCGAGTTAAAAAAT
+TTAAACATATAGAAAAGATATGAATCTGACAAAATTTAGAGAAAATAAAA
+TGTTATTCACCAAATCGCCAATTTTTCTGCATTTTTTTGTCCGTTTTACT
+TTGGTAATTCTGGTAATACAAAACTAGTTTTTTTTCAAAAAAGAATTGCA
+GGAAAAATATTTTAAATGTTTTTTGAGCACTTGAGCGCATGAGATAGAAA
+AACGTTATTATTATGCATTCCCTCATATAAAAGTTTGTTCAATTTTTTTA
+ATTAAACCCCGCTCTTTGAGAAAACTCTGGACTCTACATGGAGACTACCT
+TAATACAAATTAACTCATAAATATCGGTGATTTTCAACTAGTTATTCATA
+TGATGCAATTACTGATTTAATAACTTATAATTATGTGTCAATTTCAGACG
+TCTGTATCCGCCGATCCAAAATCTCACACGCCGATTTTGATGGCCGACGA
+GTACAAAGAACCACAGAAGCAAGGTGAGTTTAGTTCGAAAAAAAATCATA
+ACACACACCAGTAGGTTTAAAAACATTGTTAGAAAATTTGAAAAAAAAAC
+CAAAAACCGTCGTAAAACTACACTTTTTCTATTGAAAATAGAACAAACAA
+ATCAAATATCCTACATGTAAAATTTAAATCGAGTGGAATTAAATTCTTCA
+AACAAAAAGAAATCTGCATTTAATATCGATTTCTCATTCAATTGTTATGA
+ATCATAAAACATGATTTTTTACGACCTCCTCTGAATTATCTACATTGTTC
+TCTTTTTCATACTTTCCATATTCTAGTATCGATAGGACTAACACAATTTT
+AATAGTGAGTTCGTTTTTCAAACAATTGGGATTAATTTTCAACTGAACTA
+GACTGTTTCTGAACGCTCAAAACCTTCAAAATCAATGCTTCTTCAAAACG
+AAAAAATTGCACACTATAAACCTCTCACTTGAAGTGGCAGCGCTCGTTTT
+ATATTGAGAAAATATATATTCAAAAAAATGCTGCTGCTTCTTCAGCTTCT
+CGCCGGGCGCCGCCGCCAATAGTGAGTTCGTTTTTCAAACAATTGGGATT
+AATTACAAAAAAACTTAACTGCGCAATTTTTAATTGGGAAACTTTCAAAT
+TTTAACCATAACTATCAATACAGCGGTATACGAAATTTTTCTTCAAAATC
+GCACCGATACTGCATTTTTCCGGAAAAGGACAAAGTCGGCTAATTGCCGT
+TTTTTATAATTTTTGCTCATTAAGCTTATTCCATTAAAAATACAATTCTT
+GTTTAAAATTGCTGAACGGCGAATTTTGTCTACCCGTGGTGGAAATTGCC
+GGTTTGTTGATTTGCCGGAAAATTTCATTTTCGGCGTGCCGATTTGCCGT
+TTGCCGGATATCAATTTGCCTGAAACGTTTAGAGGAATACAACGGAAACA
+TTTGAAACTGTGCCTTTTTGAAATTTTTTCCCTTTTTTTTACAATATTTT
+CATAGAATTAGCTTACTTTTCAAAATAGATGTAGGAAAATTCATATGCGT
+ACAATTTTGCCAATTAAAATTTGAATTCTGAAATTTACAAAAAAATGTGC
+AAAACTACTATTCGCCGAAAATTTTTGGCAAGTTGCCGATTTGCCCGAAA
+TTTTTATTTTCGGCAAATTGGCGCTTTGCAGTTTGCCGGAAAAAATTACA
+TACACCTGTTTTCAGCCTAACTTAAAATATGATTTACTTTGAAAAATAGG
+GAATTAAATTTAAATAAAATTTTCAACTGAACTAGACTGTTTCTGAACGC
+TCAAAACCTTCAAAATCAATGCTTCTTCAAAACGAAAAAATTGCACACTA
+TAAACCTCTCACTTGAAGTGGCAGCGCTCGTTTTATATTGAGAAAATATA
+TATTCAAAAAAATGCTGCTGCTTCTTCAGCTTCTCGCCGGGCGCCGCCGC
+CACATTTACCGGCCAACCCGTTCTCTGAGGTTGTCTTGTAAGGGCGTTTT
+CATGTATATTCAGATTATTATGCATGAATTTCATTAATAACGGTATCCAC
+CCACGTATATTTCTCTTCTTCTCTCTTTCTGTTGCGACGGGGGATGTCGA
+TTGATTACGCCACGGGCGCTAGCCTATTCCGAATGCATTGAGAAATTTGA
+GACCAGATTCTGGAGTTTTTGGAAGACGAATCGTCGGCAGCGGAGCTCGA
+TTTTAATTTAATTTCGAGAGCACCCGCGTGCTCTCGCCTCGACACCCTCA
+AACTTCTTCTTCTTCTTCTTTTCGTCGTCTTTCACTTTTTTCCTTTTTCC
+TGTCCTAACCACGGCGTCTTCCTCCAATTTTCAGTTACCACGACGTCATT
+AGCTATTTTTAGTCCGAGTGTGGAGCTTGAGAATTTGAGCAATTCTGATG
+TGACATTCCTGTCGTTTTTAGCGCTAATTTTCCTAAAACCTTCAAAAATT
+TAGAAATTCTCTATCGTCTTTCAAGAGCCTAAGTTTTTTTTTTCGAAATG
+AGTTTTTTAAAATTGATCGAAATGTTTTTAAATACTGAATATTTGGGATT
+CTAGATTTTTACTACAATATTTCCTTTTCAATTTTTAATTGGACAAAATT
+TCAAAATGTTAAAAAAATTCTCCGAATTGAATGCTATTTTTCTAAAAAAT
+TTTTTTAGTGCCTGCACCAGTTGTCGTTGCTCAGGAGTCGCCGATCTTAA
+AACGAAGAAACTCTCTAGTACCATCAAGGATCAGTGGAAGGCAGTCGACG
+>CHROMOSOME_V
+GAATTCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCT
+AAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA
+GCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCATAAGC
+CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCATAAGCCTAAGCCT
+AAGCCTAAGCCTAAGCCTAAGCCTAAGCATAAGCCTAAGCCTAAGCCTAA
+GCCTAAGCATAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAACA
+TAAGCCTAAGCCTAAGCCTAAGCCTAAAACATTTGGAAATTATTTTTGAT
+CGTTTATATTCAAGTAGCAAGAAAGTGTCCTAGCGTTAAAAATAGGAAAT
+TTTTCGCTCTTTCAGAACAGTATACTCATGTCTCTGTACCGACGATATTC
+ATTTCAAAAATCGCAAAAAAAGTTTTTTTCAAAATACCACTACCATTAAA
+ACATTTGGAAATTATTTTTGATTGTTTATATTCAAGTAGCAAGAAAGTCT
+CCTAGCCTTAAAAATAGGAAATTTTTTGCTCTTTCAGACCAGTATACTCA
+TGTCTCTGTACCGACGATATTCATTTCAAAAATCGCAAAAAAAGTTTTTT
+TCAAAATACCACTACCATTAAAACATTTGGAAATTATTTTTGATTGTTTA
+TATTCAAGTAGCAAGAAAGTCTCCTAGCCTAAAAATAGGAAATTTTTTGC
+TCTTTCAGATCAGTATACTAAACATTCACGTGTGGATTAAAATTAAAAAG
+GTAGTGTTAAATAATTAAAAATCATTTAGGGGGGAACGAAACCCATAAGT
+ACTGTCATTTTTATCTTTTACCTTTTTTTTTACGTACGACGTTTTTCGCT
+GTTTTCCCTGATACAAAATGCGTTGTTCTTGTTTATTTATGTTTTTCTTG
+AAAATGTTATCAACACTGATAATCTGAAAAATTATAATTTAAAACTTAAA
+CGAAGCTAAAATGTGGCTGTTATAATACAGCGACTCAATGAAAAACTCAA
+AAAAAAGTTGACTTTGCACGCTATGGTTAAAAATGAATGAATTCTTGGTA
+CATGGTTTTTTTTGTGATTTTTCGTTGAAAAATCCACACCGTGTCAGAGA
+GAGCTGAAAATGTTCATTGAAAGCGCTAAAAAACATTTGAAAAAATGCCA
+ATTTTTCCGTAAGATAATTCGATTTGAAAGTTTGAAAACTGAATAGTAAT
+TGTGTACTTGCAAAGAACCTTGTTTGCTTTTTAGTTTATTTGATCTACCA
+AAGATTGGGTTCACTGTCTGACCATTTGGGTCACTAATCTCATAAACCGT
+CAAAACAATCCAACGTGGTACAAAGTACATCAAGTTTTTCACAAGTCCTA
+TAGTTAGCTGCGCATCCCTAATAGGTATCCCCATTAATTTTTTTTTCAAG
+AAGAATGGCAACACAAACACCCCTCTCTGATGACTCGTGTGTCAAAAACG
+AGCTCACGGAACTCTCCTCTAGTGAAACGGTCTCGAGGATTGACGAGGCC
+CCGAAATTTCATGTCAAAGCTGTCGTCGGGCGTGTTGTGATAAAACATTT
+TGGTGGCCGGGATTGTGTTTGTGTTCAGTCAGAAAGACGCTATTAGGACC
+TCCTCCCATCTTATTAGCTGTTTATCCTTCATCACAAGACATCTCAATAT
+TGGTTCCATAGGTGTAGCTTCTTCTGCTTCTTCTTCTTCTTTTGTACCTA
+CGTCATCATACATTGGTTACTGTCCTACCGAGGTTTGTTTCAAATTTGCA
+CATTTAAAATGGTATACACCTTTAAAATAAACTTAGAAGTAAGGCCTTTG
+GTCCCACTACAAAAAATTTACAGTAGTTTGGTTCAGACTTTTCTAAATTT
+AATTAAGGTTATTTTTTATTGACAAAAAATATTTTAGTTCAAGAAATATG
+TTATGTTCAGTGGGTTTCCTGTCATATACTTCTACTTACCGTATTTCCTC
+TATTAGTCTTGCATGCAAGACTAATTTTCAATTGACCCGTAGGGGTGCAA
+GACAAATAGGGGTGCAAGACTAATAGAGGCTGCAAGACTAATAGAGGAAA
+TACGGTAGTTATACTGGCAAAAGCGATAGCATTTCGAGAGAAAAATATTC
+TTAAATGTGCTCAATATGGCTGATACAGATAGGTTTTTCATTACAGACAG
+GTTTTTCATTTCAATTTTAAAAAAATACCTGACAGTTTATCAAGAAAATC
+CAGCACATTCCAGAGTTATTAGAGTATTTAGAAGTTTGCAAGTTCCCAAT
+TTTGTCAAGGGATTTTTCAAAGTTTCTCAAACTTTCCAAAAAATGCAAAA
+AAAAACATTCCAAAAGTACCAATTTTTCCAAAAAATTCCATAAATATATT
+CAGTCCACCGAACGTTTTTAGATCTAACTGAGAGTTCTCCTGAAGTTTTT
+CAGAGTTTGAAGGAATTTATAGAAGTTTCTGATGTTTTACAGGATTTTAC
+TAAAGTTTCTCAAATTATCTATAAATGCCAAATCTTTTCAGAAAGTTTTC
+AGAAAATTTCCGGAAAACCTTCAATTTTTCAAGTTTTCCAGAAGATTCTC
+GATTTTTCCAAAATCGTTTCAGAATTTTCCTAATTATTCCCATATTTCCA
+TCGACTTCTTATAGTTAATTTGATTTTCATCAAATTGATACAAATGAGAA
+AATTTGAAATTTGATAACTCACGTTTCGATGCAAAAAGAGACGAAAGGCG
+GCGTGATGCGGGCAGGATTTAGGCAGGCGGTAGGCCCTGAAACCGCGCCT
+GCCTACCATTGAACCTCTAAGCTATTCAGTTGTATTTTTTGATATTCCAG
+ATGCGTACCGACGTGGGTTCTATTCCATTAATGTGTATTCTGTCTACACT
+AACGACTGGTGTGTTCGGATATCTTCCGACAGAAGATCTCACAAATTCGA
+TAATTTCTGGAAACGGTGGTTATCCAGTTCCTCCGGACACTATTATACCG
+GCCGATGGAGATGAGGAAGGTAAGTGGATCAGAAATTAATAATTATAAAT
+TTTTTAGAGTAGGGTTTTCTTCTGAAATCTGATATTTTGTGAATTTTGCA
+AAAAATTGGAAAAATCGACAACGAAATGCAAATTGTTTCGTTAAATGCAA
+AATGGATGCGCACCTTTAAAGAGTAAAGTCTATGAAAATGCTTTTATTTG
+GTATTACAGTTCTTTTCAAAGGCACACATATTTTTCCCATTTAACAAAAA
+ATCGTCGTGACCTTATATCGTATTTTCGGCGCAAAAATCGGAACATTTCG
+CGTCTGTATAATACCCCATTTAAAGGTTTACGACGCAATAATACAACACC
+GGGTCTCGACGTGGCAAACGATTGTTTATTGATTTTCACGGGATTCTCGC
+CTTTCTCATTGAATTTTCGCGCTCCATTGGCAATCGCCTGCCGGACAACG
+CGTGGAAAAGTGTAGTGTACTCCACACGGACAAATCCATCGGTTTTACAA
+CTAAAAACGAGCCGCGACGCGACACGCAACGCGCCGTAAACCTACACAAA
+ATCTCGCAGACTCAAAATGGCCTAGTTCGGCAAACTCTGCCATTTCGATT
+TATGAGGGAGGCCAGAATTCCGTGATTTTCCCATTTCTCACGGCCTCTCT
+AAATTTCACGTTTTTCAAAATTCATCTTTTTCTCTCTGCTCTCTCACTCT
+CTCACGTGAAATATTACTTTCTGAATAATAATTTGTGTTTAATTAAATCA
+AATTTTATTGAAATAGAATTCATGATACACGATCTTGAGAAGAGCTCTGT
+CCTCCAGGCTGCGAACTGGAGCGTAGAAAGTTTTCATATTGTTAAAAACT
+GCAAAGAAATGTTCGATTCCTTGTTCTGACGTGTGATGCTTTCTCAAATA
+TGGAATTAAATGACAGACAAGGAGATGAAGTTTCGGAGTGACTCATTATT
+TCATCAGTTTCATTAGGAAAAACACTCTTTATTTATTCAAGGAACTGTTA
+AAGCAAAACTTCAATTTTGTCAATCTCTTGGTCTAAATACGTTCTATCGT
+TAGATAAATCTAACTATCTAACTGAAACGAGTACAACTATATTGTAACGC
+AAAAAAGCTAAGCGCCATAAAACACAAGTAAAACAGGCTCCAGTAAGCCT
+AAACTGTTTTTACTATAAAAAACCATTGTCATTCACCTACCTACCAAATG
+CCAATATAATTGGTTGAAAAAAATTAGTTTAATCTCCTCGCAAGATTTTT
+TTCTCCGAAATTTAAGATTGGGCGCTTAGTGATATCATAACTCTGCAGCC
+ATCAGAAAAACTGAAATGTATTTAAACTGTAAGTTTTAATCGTTTTATGA
+GGATTATTTCTTTAGTTGACAGTTTTTTGATAGCTTCTTTAGTTATTGAG
+CTACGGGCTTCCAAACAAAACCAATCAAAAACCACTATAAACCACAATGT
+CCTAAAAGTGAAATTACTCAGTCAATTTTTAACCAAATCACGGCATTAAT
+GTCTTGATATCTTCATTGAACAATTTGTAAAAATCGTAAGGCGGTAGTTT
+TTTGATAAATGTCATCGTTTTTTAGTAAAATTGCGTTAACCATTCAAAAA
+TGGCCCATTTTTGGTGTTTTCAGGCCTAATTCTTGTTTTTGAAATTCCGG
+AGCCAGTTTTTATCGAAAATTTTTGTGCAATGTCAAAAAATGACCGGAAA
+AAAATTCTCTACAATCGTAAGGCGGTACTTTTTAAAATTTCGTTTCCATT
+CTTCCCCAGGGATCCCGTAAAAAACCAATTTTTCGACTAGGTCTCACATT
+TTGCCCTACAAGAGCATAGTTAATGTTATAAATTTGGATTTTTTGGTCGA
+ATTTGATGAGGTAATATTCAGTTGTTTGTTTATTGTTGGAAAATCTGAAG
+ATTTATCAGCGAATCGCCCGATTTCGCCAATTATGACCAAAAAACCCCTA
+GTTTAGGATTTTCACGAATGGATGAGTTCATTGATACGCTTCCACGCTGT
+>CHROMOSOME_X
+CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCT
+AAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA
+GCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGC
+CTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCT
+AAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAAGCCTAA
+GCCTAAGCCTAATCTGTGCTCCAAAGCCTTCGAACTGACGGACTTGTGTC
+CCGAAGTCGAACTCTTGAAGTTGTCACCGAGTTGGCTAATAAGAAAGACG
+CTACGTTGTCTTTTTAGTAAGTTTTCGTCGAAATTCTGGAAAAAAAATCT
+GAAAAAAATGAGAAAAATTGAAGTTTCTTGTGAAAACGTGCAGCAGCCGA
+CAACTAACGGGACTGGGAAAATTGAAATTTTTAACACAGTTAAAATGCGA
+TGTGCGCATAGTGGGTGAAAGGCCATAATGCGCGCACCGCGTGTGGCGAC
+CACCTATTATGCACCTATCGCGAACGGTTCGCGATGGGTCCATAATGTAT
+CCATGATGCTTCCACTCACGAAACAAACAATTCGAAATATATATTGTTTT
+TCCGCCTATTTTTTTAACATTTTATTGCAATTTTTATTGAATTTTTGATT
+TTCACTGGTTTTTTTTCTTGAAATTTTGTTTCGTATGTGGTATTTTGTAA
+TAATCATAATATTTTTTTCTAAATTGTGTGTCTTTTAGAGAAAACACTGC
+TCTAACCAGTTGAGGCATTTAAAAACATCATTTAAACAACATGGCAAGCA
+TTATTTCGTTCCTAATAAATGGAAGCATAGTCAGGATTACTGTAGTTTCA
+CATGTATTTAGCCATTAAAATTGTAATCTGAGTTTTCATCGGTATTTGCG
+CATACTCAGAAAATTTTGTTAAATATCTTGTCTGTTCCTGTATTTTCAAG
+AGCGAAATATCGTCAAAATCAGATTATTTCGTTGAATCTGGAAATGCCCA
+CTGTTCTTCATGCCTACTCGTGTCTATTTCTCATCAGCGTTATAACTCAC
+CTTTTAAATAATATTGTAGAAACAAATTTTTTGCAGCTTCTCTTCGAGCA
+GCAGACTTCACAAAAACTTCATCAACAAGAAAAAACGTGAAAATCTTCAA
+CATCGGAATGTCTAGGTGAAGGATGTCGGAACGGGCAAGGTTTGGAGCAC
+GGCTCAGCTTTTTTAGATTTTAGATTTTAATTTAGAAACACACCACCGAA
+GAGGAGGAGATAAAGATGGCTCGGCTCCAGAATGCATTGAAAGTTGTTGG
+ATGGTCGAATGGATTGAAAGCAATTGTAAAGAAGGAGTTACCCGGAAGCC
+CTGCCAAAAAGCAAAAACCGGCATCGGTTGCGCCGAAAATTTTGGACTCC
+TCGATCGGAAGAGTGAGTTTGCTGATTTTCAAAAAATAGGATGAAAGGCT
+GAATAATTTGAGCTCTCAATTGCTAAAAATATACGGATGGACAAAACTAC
+GATCATCATTGGTCACAAAGTTGCAGCTCCGAAAAGAGAATTCGTCTGGA
+ATTCTGGAAGTTCACAAGAATGGTGAGTACTTACCTTTCAAGTGAAAATT
+GAGGAAAAATTGAGAAAGAAATGTGTTGAAAGATGCAAAAAAATGACAAA
+AATTCAGCTTATCCTGCTAAAATTACGCGTGAAAAAGCATATTTTGTGCT
+TGAAAATCGCAAAAAAAATGCATTAGAAAAACCGATTTTATTTAGTCCTC
+CTAACAAATCGATTTTTGTAGACCTGGAGTCATCCTAGCAAACGAGGCAA
+CACTGGAAGAGGACGAAAAACGTTAAGATTCCGTATGAAGATGTCAGAAA
+ACCGAGTTAGGAGGAACTTGGAATTAAATTTTTGAGTTTTCTTTTTTCTA
+TAATTTTTTAAGCTCACTTTTTATTCTTTTTGTTGTTCTCCCACTTAGGC
+CATGTTAATAAATGTGTTTTTGTTAAGAAAACTGTCTTAAATGCTCAGGA
+TCAGGTTTTATTATTAAAAAAACAAACCCACAAAGCGCACATAATTTATG
+TTCGCGATGCTCGCAAAATGCATCTCAAGTTCGCGATGGACGCACAATGC
+GCGCGCAATGGGCATCATTTCCGGTTCCTTTTTAACACACGCGCGATCCA
+CTCCGAAAGCACTATGCGCACATCGCATTTTAACTGTGAATGAAAATTTG
+AAAAAAAAAACTAAATTTGAGAATTTTTGAGTTAAAAAATTCCAAATTGC
+AGAGAAATAAAAAATAAAATTTTTAGAGAATATATCGAAAGAAATTCAAA
+TTTTTAAGAAAAAATCCCAAAAATAAATCATTTTTCTAGAAAAAAAAAGC
+AAAAAGTTCCCATTTTGCGATAAAAATCGAAAAAATCCCGATTTTTTTAC
+AATTTTCTAAAAAAAAACTGAAAAAAATCCACATTTTTCAGAAAAAAACG
+CTAAAATTTTAATTTTTTCTAGAAAAAAACAAAATTTTCAATAAAAAATC
+CAAAAATAAAACCAAAATTAAAAAATTATAATAATTACGGGTAAAATCGT
+ATGAAATCCCGTTTTTTTTTTAATCGTAATTATTTTCAATTTTTTGGTTT
+TCTCCTCAAAAAAAATTGTTTTTTTTCCCATTTTTCTTTAAAAATTGAAA
+GTTTTCCAATTTTTCTCGAAATATTGACTCAAAATTAGCTTTTTCTTCGA
+ATTTTTAATAAAAATTTTCACTTTCGCGACCCGTTAGTTGTCGGCTGCAC
+GGTTTTCTGAAAATTGAGAAATAAAATTAGAAAAGTTGCAAAATTGAAAA
+AAAAAACCGCAAAAAACTGAAATTTTCTAGGCAAAAAAAAATAAAAGAAA
+TCCACAAATTTTTCGATAAAAATTGAAAAAATCCAAATTTTCCTGAAAAA
+AATCCCAAAAATCCAATTTTTCTACAAAAAAAACCCAAAAATCCACTCCT
+TTTCGATAAAAATTTGAAAAAATTTCGATTTTTCAAGAGAAAATTCCGAT
+TTTCTAGAAAAAAAACCCCAAAAAACTATAATTTTCCTTTAAAAAAAACC
+CCAAAAATCCAAATTTTTGTACAAAAAATACCAAAAAATCCACATTTTTC
+AATAAAAATTAGAAAAAAAAAACAATTTTTGCTGAAAAAAAACTCAAAAA
+TCCAATTTTTCTACAAAAAATACAAAAAAAATCACGATTTTCCTGAAAAA
+AACCCAAGAAACTATAATTTTCCTGAAAAAAAAATCCAAAAAAAAACCGG
+GAAAAAAACAAAAGAAATCCAAATTTTTCGATAAAAAAATTGAAAAAATT
+CCGATTTTTCAGGAATAAATTCGGGAAAAAATTCAATTTTTCTAGTAAAA
+AACCCAAAAAAAACCCAATTTTTTTGCAGTTTCCGTCACTTCTTCTACCA
+CCGTTTCCACAGTAATCTCATCGAAGGCTCAGGTCGCCTACTCGACAAAA
+TTAATGATACTACTGCTGCCCAACAACAACTACAAACTACAAACGAACTC
+GACGGCGATGGCCCAGAAATTGCAATCGCCGCGGCCAAAGCATTCCATCC
+GACTGAAAAATTCGATTTGGAAATGAATGTGGACGACGATGAAATTCTGA
+AAGTATTTGATATACAAGAACAAGAGCAAATTGTGATGAAAAAAATCCGA
+CATTTGGAGAATTCTGACTTACATTTCGAGCGAATTCATGTGAATTTGGC
+GAAAAAAGAGCGATTTTTTGACGACGTTCAGAGCTCGGAAAATGACTCAA
+GCGACGAAAAACTCGCCGAAATTTGCGATTTTTTGAGCCAAAATTGCCGG
+GAAATCTCGAATGCTGCGAAGCCTCCTCGAGCAACACTTGACGAATGGAT
+TCAGACTGGAAAATTCGAAATACAACGTCGTCGAGAGATCCGGGCGGTTT
+GCCACGTCATCAAGGCCATCGGTCAGATGGGAATTACACTTGGCGAGCTG
+TGTGGAAAATTGAAAATTGCCATAGAGCAAATTGCCGGAATTTTGGCCGA
+TTTGAGCGGAGACAAGAAATGGTGTCCGAGACCTTGGATTGCGCCGGAAG
+GTTTTCTTTTTTTTTTAAGGGATTTTTGGGGCGAAAAATTTGGATTTGGC
+TCACCACGCGCGAGCTTTGATTTAAAGGTGTTTTCGCGGTGAGACCCGGA
+AATTTTATTTTTCCTAAATCTCTCTGAACCCGGTCATGATTATACTTAAA
+TGAAAGCTCACGGCGAGCTGAATTCGAATACTAAGTGTATGGTTGTTTAG
+CTACAGTAACCTGACACTGAATTTCGCGGCGAGACCCGAAAATCCCCAAA
+AACTCTCAAAAACCGTCTTAGAATCGATCAAAATATGTCAAGATTATACT
+TAAAGGAGGACTAACGGTTCGGACGATTTTGAACGTATAGACCAAAAATA
+AGCTCAAATGAACGAAATTCGTAATGAAACTGCTCAAAAATTTTTCAAAA
+ATTTTTTATGGCGGTTCAAAATTTTGAAAAAAATTACACTGATTTTGGCT
+AAAATCACGATTTTTTCTCATTTTTCCGTGTCACATTTGTCCGAAGTTGG
+TTTTTTTAGAATTATCGTCCTTTATTACATATTTTGGTAATAAATCTCAT
+TTAATTTCGTCGATTAAAGTGCATTTAAAGCCGATAAATAACCAGTTTCG
+ATGATTTTTGGTTACCTATCGGCTTTAAATGTACCTTAATCGATGAAATT
+AAATGAGATAATCTACCAATATATGTAATAAAGGACGATACTTCCAAAAA
+AGCCAACTTCGGTCAGATGTGACACGGAAAAATGGGAAAAATTCGTGATT
+TTAGCCAAAATCAGTGTAATTTTTTTCAAAATTTTGAACCGCCATAAAAG
+ATTTTTGAAAAATTTTTGAGCAGTTTCATTACGAAATTCATTTAAGTATA
+ATCATGAGCGGGTTCAGAGAGATTTAGGAAAAATAAAATTTCCGGGTCTC
+>CHROMOSOME_MtDNA
+CAGTAAATAGTTTAATAAAAATATAGCATTTGGGTTGCTAAGATATTATT
+ACTGATAGAATTTTTAGTTTAATTTAGAATGTATCACTTACAATGATGGG
+GTTTAAAATTCTATAGTAAAAGTGTTTTTTGTTTTAGCTGTTTTAAGTAG
+GATTATTAGATATATTAATATTGACCCTATAAAAAGAAGTTTTTTTCTTA
+TCTTTTCACTACTTTTTAGTATACCAGTTATTTCAATGAGAATACATATT
+TGGTTTTCTTACTTTATTTGTTTATTATTTTTAAGTGGTATTTTTGTTAT
+TTTGGTATATTTTTCTAGTTTATCTAAAATTAATGTAGTGAAAAGTTATA
+TAGCTGTGTTTTTACTTTTGTTAAGAATGTTATATTTTTCTCCCACAGTA
+TTAACTTATAGAAGATATTTAGGTTTAAGAGGTTTTTATTATAGTATTTA
+CTGGTTTATTTTTTGTTTTATTTTAGTATGTTTATTATTTTTTATAAATT
+TTAGTAGTTATTTTTTAAATTTTTCAGGTGCTTTACGTAAAGTTTAAAAT
+TATGTTTTTATTTGTTAGATTATTTATATTTATTTTTAAATGACAACGTT
+TAATTTTTATTCTAATTTCTTTAGAATTTATAATGTTGAGATTATTTTTA
+AAATTTTCTTATGTTTTAGGGGAAATAATGTTTTTTTATTTTATGTGTTT
+TTCTGTTATTTCAAGAATCCTGGGTATGGTAGTTATAGTAGGTAATATAA
+AATTTTTTGGTAGTGATAATTGTATTTTTTAGTAACAGATATAAGTTAAG
+TTTAAACTATTGATCTTCAAAATCAAAAATTTATTTCTGTAGAGATAATA
+GTATAAATAAGTATGTTTCTTTTTCGCAGAAATGGTTTTTTATCTTATAA
+AGTTTTCTTTCAGGGAATTAAAATTTGATCATGGTTTAAGATGATTTAAA
+ATGGTATTATCTAAATTTGATTTACAGAGTAGGCAATAAAAATTTACCTC
+GGCAATTTATCGCTTGTAAAATACTTGTTCCAGAATAATCGGCTAGACTT
+GTTAAAGCTTGTACTTTAATTGATGTTAATTATGAAATTATTATATTTTC
+TTTTAGATCTATGGTAGAATTTGGATTTATATTAGTGAATTTTCATAATT
+TTAAGATTTGTTGAACAAAGCAGATTAGTACCTGGTTAGACAAAAATTAA
+AAGAGCAGGAGTAAAGTTGTATTTAAACTGAAAAGATATTGGCAGACATT
+CTAAATTATCTTTGGAGGCTGAGTAGTAACTGAGAACCCTCATTAACTAC
+TTAATTTTTTGACTCGTGTATGATCGTTTATTTTATTCTTAAGGATTATA
+ATAAAAAATTTTTAATTTATTAAAATAGATATATACCCGGTTTATGATTT
+AAGAAACATTTGGCCTACAATATTTTATATTATGGATTTTAGTTTTAGTT
+AACTAAATGAAATTGTAAAAGACAGTAAAAAATTCTTAATGTATTTTTGA
+AGATTATCTAGAAGTGGTACAAATCATCCATCAATTGCCCAAAGGGGAGT
+AAGTTGTAGTAAAGTAGATTTAGGGGAACCTGAATCTAGTAATAAAACTA
+TTTTTAAATATGTTTTGAAAACATGTTTTGAGGTAACTCGTAGTTTTTAA
+GAGTTAGTTTAATATAGAATTGTTGACTGTTAATCAAAAGGTGTACCTCT
+TAATATAAGAGTTTAGTTTAAGTTAAAACGTTAGATTGTAAATCTAAAGA
+TTATTGCTCTTGATAATTTTAGTTTTACTTATAGTTATTTTAATGATGAT
+TTTTATTGTTCAAAGAATCGCTTTTATTACTCTATATGAGCGTCATTTAT
+TGGGAAGAAGACAAAATCGTCTAGGGCCCACCAAGGTTACATTTATGGGA
+TTAGCACAAGCTTTATTGGATGGGGTTAAACTTTTAAAAAAAGAACAAAT
+AACACCCTTAAATTCCTCTGAAGTATCATTTTTACTTGTACCAGGAATTT
+CTTTTGTTGTAATATATTTAGAATGATTTACGTTACCATATTTTTTTGAT
+TTTATTAGTTTTGAGTATTCAGTTTTATTTTTTTTATGTTTAATTGGATT
+TTCTGTTTATACAACTTTAATTAGCGGTATCGTAAGAAAATCAAAATATG
+GTATAATTGGGGCCATCCGTGCTAGAAGACAAAGAATTTCTTATGAAATT
+GCTTTTTCTTTATATGTTTTGTGTATTATTATTCATAATAATGTTTTTAA
+TTTTGTTTCAAAATTTAATTTGAGACTTTTAATTATTTACATCCCATTTT
+TAATTATAGTAATTGCTGAACTTAACCGGGCGCCATTTGATTTTTCTGAA
+GGTGAAAGGGAGTTAGTTAGAGGATTTAATGTGGAGTTTGCCAGAGTAGC
+TTTTGTTTTATTATTTTTAAGGGAATATGGAAGATTAATTTTTTTTAGGG
+TACTTTCTTCTGCTATATTTTTTAAATTTTCAATTTTTATAGCATTTAGT
+ATTTTTTCATTATTAATTTTTATTCGTAGTTCATACCCTCGTTATCGTTA
+TGATTTAATAATAAGTTTATTTTGATTTAAACTTTTACCAATCTCTTTAA
+TTATATTGTGTTTTTACGCAGTTATTTTTTATTATTAATCAAGTTTATTT
+TTTAGACATTTTTATATTTGTTTTTGTTTTACAATTTTTGTTTTATTTTA
+AAGAAAGTATATTAAATACTTTAGTGAAAAAATTTCTTAATAGGTTAGTA
+GGAGTATTTAGATATACAAATACTTTACCATTAAGGTCAGTAATTTCTAT
+TTTTACTTTTATTGTTCTTTTAACTTGTTGTTTTGGAGGTTATTTTACTT
+ACTCTTTTTGTCCTTGTGGAATGGTTGAATTTACTTTTGTTTATGCTGCT
+GTAGCGTGATTAAGTACTTTGTTAACTTTTATTTCAAGAGAAAAATTTTC
+AGTTTATATAAGAAAACCAGGAGACACATATTTGAAAACTCTTAGAATGC
+TATTAATTGAAATCGTTAGAGAATTTTCTCGTCCACTTGCTTTAACAGTG
+CGTTTAACAGTTAATATTACTGTTGGTCATTTAGTTAGAATAATGCTTTA
+TCAAGGATTAGAATTAAGAATAGGTGATCAGTATATTTGATTATCAATTT
+TAGCCATTATAATAGAATGTTTTGTTTTCTTCATTCAAAGTTATATTTTC
+TCTCGTTTAATTTTTTTATATCTTAATGAGTAATAAAAAAAAAAAGATGT
+TAACTTAAGTTTTAAAGTGCCAAACTTTTAATTTGGAAATGGTGGACCAC
+ATCTTAGTTGATATAGCATAAGAAGTGCATTTGTTTTAAGCGCAAAAGAT
+ATCCGTCAACTAACGAGTTCATAAAGCAAGTCTTCTAAATTTGTTCTAGG
+TTAAATCCTGCTCGTTTTTGATTGTTTTTATTTCTTTATTTACCTTGTTT
+TTAACATTATTAAGAATTTTGACTAATAACGTTATTGTTTGATGAAGAAT
+TTTTTTATTGATAACTGTAGTTTTTATTCTATTAAATAAAAGCAGCAAGA
+GATATACCAGAATTTTTAATTATTTTGTTATTCAAGAGTCTTTAGGTTTA
+TTATTTCTTCTTTGTAGAGGAGGTCTATTACAATTTTTTATTATTTTATT
+GAAAATTGGTGTAGCACCGCTCCACTTTTGAATTTTTAATGTAACAAATA
+ACATTTTTAATTATGGGCTAATGTGGTTTTTAACATTTCAAAAATTACCA
+TTTTTAACTATTTTATTACAAATTTTTTGGTTAAGATCCGTGTATATTTT
+GTTATTTGGTTTATTGATTTGTTATGTTCAAATTTTTGTCATAAAAAGTT
+ATAAAAATTTGTTAATTATTTCATCCACAGAGTCTTTTAATTGGATTGTT
+TTGGGAGTATTTTTTTCAATGTTTAATACATTTTATTTATTTATTTATTA
+CTTTGTATTAATAGTTTTATTAATTTCTAAGTTTTCTAAAACTAGGGGTT
+ATAATTTTATTAATTGAGAAACAACATTAGTATTTTTAAATATTCCATTT
+AGAGTTTCATTTTTTGTAAAAATTTTCTCATTGAGGGAAATTTTTAAATA
+TGATAGATTCTTTACTCTATTTTTGCTTTTTACAATATTTTTATCTGTAT
+TGGCATTTAGATTTTGATTAATTAACTTGAGAATGAAAAATAATGAAGAA
+ACTTCAAATAATAATAAAATAAATTATTTTATTATTTTTCCGTTAATAGT
+TATTTCTATTATTTAATTACTTTTCTAGTAAAATATATTATATTATCTTG
+ATAAGGTAAAGTTCCAGTTGGGAGAAGTAAGATGTAAAATAGATATTACT
+ATGTTTGGTTACGGTCCAAAAAGATGCACATCTTTGCGATCTAGTTTAGA
+AAAAATATTTGTTTTTGGTGCAAAAGAGTTTGATTGCATTTAGTTTACTC
+TTTTAGTTTATAATTAAAATATGGCCCTGAAGAGGCTAAGAATATTAGGA
+GTATTGAAAATTAATAATAGATTATTAAATTTTGTTAATGGGATGTTGGT
+GACATTGCCATCTAGAAAAACTTTAACATTAAGATGAAATTTTGGTAGTA
+TATTGGGTATAGTTTTAATCTTTCAGATTTTAACAGGTACATTTTTAGCA
+TTTTATTATACGCCCGATAGGTTAATAGCATTTTCAACAGTGCAGTATAT
+TATGTATGAGGTAAATTTTGGATGAGTATTTCGAATTTTTCATTTTAATG
+GGGCCAGGTTATTTTTTATTTTTTTGTATTTACATATTTTTAAAGGGTTA
+TTTTTTATAAGATATCGTTTAAAAAAAGTATGAATGTCTGGTTTAACAAT
+TTATTTATTAGTAATAATAGAAGCTTTTATAGGTTATGTTTTAGTTTGAG
+CTCAAATAAGATTTTGAGCAGCAGTAGTTATTACTAGACTTTTAAGAGTT
+ATTCCAATTTGAGGGCCAACTATTGTTACTTGAATTTGAAGAGGTTTTGG
--- /dev/null
+CHROMOSOME_I 1009800 14 50 51
+CHROMOSOME_II 5000 1030025 50 51
+CHROMOSOME_III 5000 1035141 50 51
+CHROMOSOME_IV 5000 1040256 50 51
+CHROMOSOME_V 5000 1045370 50 51
+CHROMOSOME_X 5000 1050484 50 51
+CHROMOSOME_MtDNA 5000 1055602 50 51
--- /dev/null
+#!/usr/bin/perl -w
+#
+# Copyright (C) 2013 Genome Research Ltd.
+#
+# Author: James Bonfield <jkb@sanger.ac.uk>
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in
+# all copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+# DEALINGS IN THE SOFTWARE.
+
+# Compares two SAM files to report differences.
+# Optionally can skip header or ignore specific types of diff.
+
+use strict;
+use Getopt::Long;
+
+my %opts;
+GetOptions(\%opts, 'noqual', 'noaux', 'notemplate', 'unknownrg', 'nomd', 'template-1', 'noflag', 'Baux');
+
+my ($fn1, $fn2) = @ARGV;
+open(my $fd1, "<", $fn1) || die $!;
+open(my $fd2, "<", $fn2) || die $!;
+
+# Headers
+my ($c1,$c2)=(1,1);
+my (@hd1, @hd2, $ln1, $ln2);
+while (<$fd1>) {
+ if (/^@/) {
+ push(@hd1, $_);
+ } else {
+ $ln1 = $_;
+ last;
+ }
+ $c1++;
+}
+
+while (<$fd2>) {
+ if (/^@/) {
+ push(@hd2, $_);
+ } else {
+ $ln2 = $_;
+ last;
+ }
+ $c2++;
+}
+
+# FIXME: to do
+#print "@hd1\n";
+#print "@hd2\n";
+
+# Compare lines
+while ($ln1 && $ln2) {
+ chomp($ln1);
+ chomp($ln2);
+
+ # Java CRAM adds RG:Z:UNKNOWN when the read-group is absent
+ if (exists $opts{unknownrg}) {
+ $ln1 =~ s/\tRG:Z:UNKNOWN//;
+ $ln2 =~ s/\tRG:Z:UNKNOWN//;
+ }
+
+ if (exists $opts{nomd}) {
+ $ln1 =~ s/\tMD:Z:[A-Z0-9^]*//;
+ $ln2 =~ s/\tMD:Z:[A-Z0-9^]*//;
+ $ln1 =~ s/\tNM:i:\d+//;
+ $ln2 =~ s/\tNM:i:\d+//;
+ }
+
+ my @ln1 = split("\t", $ln1);
+ my @ln2 = split("\t", $ln2);
+
+ # Fix BWA bug: unmapped data should have no alignments
+ if ($ln1[1] & 4) { $ln1[4] = 0; $ln1[5] = "*"; }
+ if ($ln2[1] & 4) { $ln2[4] = 0; $ln2[5] = "*"; }
+
+ # Canonicalise floating point numbers
+ map {s/^(..):f:(.*)/{"$1:f:".($2+0)}/e} @ln1[11..$#ln1];
+ map {s/^(..):f:(.*)/{"$1:f:".($2+0)}/e} @ln2[11..$#ln2];
+
+
+ if (exists $opts{Baux}) {
+ # Turn ??:H:<hex> into ??:B:c,<vals> so we can compare
+ # Cramtools.jar vs htslib encodings. Probably doable with (un)pack
+ map {s/^(..):H:(.*)/{"$1:B:C,".join(",",map {$_=hex $_} $2=~m:..:g)}/e} @ln1[11..$#ln1];
+ map {s/^(..):H:(.*)/{"$1:B:C,".join(",",map {$_=hex $_} $2=~m:..:g)}/e} @ln2[11..$#ln2];
+
+ # Canonicalise ??:B:? data series to be unsigned
+ map {s/^(..):B:c,(.*)/{"$1:B:C,".join(",",map {$_=($_+256)&255} split(",",$2))}/e} @ln1[11..$#ln1];
+ map {s/^(..):B:c,(.*)/{"$1:B:C,".join(",",map {$_=($_+256)&255} split(",",$2))}/e} @ln2[11..$#ln2];
+
+ map {s/^(..):B:s,(.*)/{"$1:B:S,".join(",",map {$_=($_+65536)&65535} split(",",$2))}/e} @ln1[11..$#ln1];
+ map {s/^(..):B:s,(.*)/{"$1:B:S,".join(",",map {$_=($_+65536)&65535} split(",",$2))}/e} @ln2[11..$#ln2];
+
+ map {s/^(..):B:i,(.*)/{"$1:B:I,".join(",",map {$_=($_+4294967296)&4294967295} split(",",$2))}/e} @ln1[11..$#ln1];
+ map {s/^(..):B:i,(.*)/{"$1:B:I,".join(",",map {$_=($_+4294967296)&4294967295} split(",",$2))}/e} @ln2[11..$#ln2];
+ }
+
+ # Rationalise order of auxiliary fields
+ if (exists $opts{noaux}) {
+ @ln1 = @ln1[0..10];
+ @ln2 = @ln2[0..10];
+ } else {
+ #my @a=@ln1[11..$#ln1];print "<<<@a>>>\n";
+ @ln1[11..$#ln1] = sort @ln1[11..$#ln1];
+ @ln2[11..$#ln2] = sort @ln2[11..$#ln2];
+ }
+
+ if (exists $opts{noqual}) {
+ $ln1[10] = "*";
+ $ln2[10] = "*";
+ }
+
+ if (exists $opts{notemplate}) {
+ @ln1[6..8] = qw/* 0 0/;
+ @ln2[6..8] = qw/* 0 0/;
+ }
+
+ if (exists $opts{noflag}) {
+ $ln1[1] = 0; $ln2[1] = 0;
+ }
+
+ if (exists $opts{'template-1'}) {
+ if (abs($ln1[8] - $ln2[8]) == 1) {
+ $ln1[8] = $ln2[8];
+ }
+ }
+
+ # Cram doesn't uppercase the reference
+ $ln1[9] = uc($ln1[9]);
+ $ln2[9] = uc($ln2[9]);
+
+ # Cram will populate a sequence string that starts as "*"
+ $ln2[9] = "*" if ($ln1[9] eq "*");
+
+ # Fix 0<op> cigar fields
+ $ln1[5] =~ s/(\D|^)0\D/$1/g;
+ $ln1[5] =~ s/^$/*/g;
+ $ln2[5] =~ s/(\D|^)0\D/$1/g;
+ $ln2[5] =~ s/^$/*/g;
+
+ # Fix 10M10M cigar to 20M
+ $ln1[5] =~ s/(\d+)(\D)(\d+)(\2)/$1+$3.$2/e;
+ $ln2[5] =~ s/(\d+)(\D)(\d+)(\2)/$1+$3.$2/e;
+
+ if ("@ln1" ne "@ln2") {
+ print "Diff at lines $fn1:$c1, $fn2:$c2\n";
+ my @s1 = split("","@ln1");
+ my @s2 = split("","@ln2");
+ my $ptr = "";
+ for (my $i=0; $i < $#s1; $i++) {
+ if ($s1[$i] eq $s2[$i]) {
+ $ptr .= "-";
+ } else {
+ last;
+ }
+ }
+ print "1\t@ln1\n2\t@ln2\n\t$ptr^\n\n";
+ exit(1);
+ }
+
+ $ln1 = <$fd1>;
+ $ln2 = <$fd2>;
+
+ $c1++; $c2++;
+}
+
+if (defined($ln1)) {
+ print "EOF on $fn1\n";
+ exit(1);
+}
+
+if (defined($ln2)) {
+ print "EOF on $fn2\n";
+ exit(1);
+}
+
+close($fd1);
+close($fd2);
+
+exit(0);
--- /dev/null
+#!/bin/sh
+
+#
+# -----------------------------------------------------------------------------
+# Author: James Bonfield.
+#
+# This cross validation script is designed to run the htslib test_view
+# and cramtools.jar CRAM implementations to test compatibility between
+# implementations.
+#
+# The test set may contain many dubious and ambiguous SAM cases, such as
+# single base reads (is that quality "*" really meaning Q9 or no quality?).
+# Some of these may fail one or the other implementations and be acceptable
+# in the short-term, so to spot more important regressions we can tag
+# specific cases as being known-pass or known-fail.
+# -----------------------------------------------------------------------------
+#
+
+vers=3.0
+
+cramtools_jar=$HOME/work/cram/cramtools/cramtools-$vers.jar
+
+test_view="./test_view -o VERSION=$vers"
+
+cramtools="/software/bin/java -Xmx4000m -jar $cramtools_jar"
+cramtools="/software/bin/java -Xmx4000m -jar $cramtools_jar"
+
+run_out() {
+ out=$1; shift
+ echo "$@ > $out"
+ $@ > $out
+}
+
+run() {
+ echo "$@"
+ $@
+}
+
+
+sam_to_Ccram() {
+ run_out _tmp.cram $test_view -C -t $1 $2
+ #run_out _tmp.cram $HOME/io_lib/trunk/build.seq3/progs/scramble -r $1 -O CRAM $2
+ if [ $? != 0 ]
+ then
+ crash=`expr $crash + 1`
+ false
+ fi
+}
+
+Ccram_to_sam() {
+ run_out _tmp.sam $test_view -i REFERENCE=$1 _tmp.cram
+ #run_out _tmp.sam $HOME/io_lib/trunk/build.seq3/progs/scramble -r $1 _tmp.cram
+
+ if [ $? != 0 ]
+ then
+ crash=`expr $crash + 1`
+ false
+ fi
+}
+
+sam_to_Jcram() {
+ run $cramtools cram -R $1 -I $2 -O _tmp.cram -n -Q --capture-all-tags
+ if [ $? != 0 ]
+ then
+ crash=`expr $crash + 1`
+ false
+ fi
+}
+
+Jcram_to_sam() {
+ run $cramtools bam -R $1 -I _tmp.cram -O _tmp.sam
+
+ if [ $? != 0 ]
+ then
+ crash=`expr $crash + 1`
+ false
+ fi
+}
+
+compare_sam() {
+ #run ./compare_sam.pl $i _tmp.sam -nomd -notemplate -unknownrg -Baux
+ run ./compare_sam.pl $i _tmp.sam -nomd -Baux
+ if [ $? != 0 ]
+ then
+ fails=`expr $fails + 1`
+ false
+ fi
+}
+
+trials=0
+fails=0
+crash=0
+
+files=`ls -1 *#*.sam`
+
+# Restrict to known workers from SAM->CRAM->CRAM in cramtools
+#files="auxf#values.sam c1#bounds.sam c1#noseq.sam c1#pad1.sam c1#pad2.sam c1#pad3.sam c1#unknown.sam ce#1.sam ce#2.sam ce#5b.sam ce#large_seq.sam ce#tag_depadded.sam ce#tag_padded.sam ce#unmap.sam ce#unmap1.sam ce#unmap2.sam xx#large_aux.sam xx#large_aux2.sam xx#pair.sam xx#rg.sam xx#unsorted.sam"
+
+for i in $files
+do
+ r=`echo $i | sed 's/#.*/.fa/'`
+ echo "=== $i"
+
+ # C to C
+ trials=`expr $trials + 1`
+ sam_to_Ccram $r $i && Ccram_to_sam $r && compare_sam $i _tmp.sam
+
+ # Java to Java
+ trials=`expr $trials + 1`
+ sam_to_Jcram $r $i && Jcram_to_sam $r && compare_sam $i _tmp.sam
+
+ # C to Java
+ trials=`expr $trials + 1`
+ sam_to_Ccram $r $i && Jcram_to_sam $r && compare_sam $i _tmp.sam
+
+ # Java to C
+ trials=`expr $trials + 1`
+ sam_to_Jcram $r $i && Ccram_to_sam $r && compare_sam $i _tmp.sam
+done
+
+# Overcounts failures as an early fail can lead to 1 or 2 more fails.
+echo ""
+echo ============
+echo No. tests: $trials
+echo No. diffs: $fails
+echo No. crash: $crash
--- /dev/null
+>
+ATGC
+>trailingblank1
+AAATTTGGGCCC
+TTTGGGCCCAAA
+GGGCCCAAA
+
+>trailingblank2 with last dna line the same length
+AAATTTGGGCCCAAATTTGGGCCC
+TTTGGGCCCAAATTTGGGCCCAAA
+GGGCCCAAATTTGGGCCCAAATTT
+
+> foo
+TGCATG
+CA
+> bar description
+TTTTAAAA
--- /dev/null
+/* test/fieldarith.c -- CIGAR field arithmetic test suite.
+
+ Copyright (C) 2013 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+
+#include "htslib/sam.h"
+
+int ntests = 0;
+int nfailures = 0;
+
+void check(const bam1_t *aln, const char *testname, const char *tag, int value)
+{
+ int32_t refvalue;
+ uint8_t *aux = bam_aux_get(aln, tag);
+ if (!aux) return;
+ ntests++;
+ refvalue = bam_aux2i(aux);
+ if (value != refvalue) {
+ fprintf(stderr, "%s FAIL for %s: computed %d != %d expected\n",
+ testname, bam_get_qname(aln), value, refvalue);
+ nfailures++;
+ }
+}
+
+int main(int argc, char **argv)
+{
+ bam_hdr_t *header;
+ bam1_t *aln = bam_init1();
+ int i;
+
+ for (i = 1; i < argc; i++) {
+ samFile *in = sam_open(argv[i], "r");
+ if (in == NULL) { perror(argv[1]); return 1; }
+
+ header = sam_hdr_read(in);
+ while (sam_read1(in, header, aln) >= 0) {
+ check(aln, "cigar2qlen", "XQ",
+ bam_cigar2qlen(aln->core.n_cigar, bam_get_cigar(aln)));
+ check(aln, "cigar2rlen", "XR",
+ bam_cigar2rlen(aln->core.n_cigar, bam_get_cigar(aln)));
+ check(aln, "endpos", "XE", bam_endpos(aln));
+ }
+
+ bam_hdr_destroy(header);
+ sam_close(in);
+ }
+
+ bam_destroy1(aln);
+
+ return (nfailures > 0);
+}
--- /dev/null
+@SQ SN:one LN:1000
+@SQ SN:two LN:500
+@CO For each SAM record that has each listed aux field, performs these tests:
+@CO XQ is the expected result for bam_cigar2qlen()
+@CO XR is the expected result for bam_cigar2rlen()
+@CO XE is the expected result for bam_endpos()
+@CO (Note that these are all zero-based, while POS is one-based in SAM)
+r1 0 one 50 20 8M * 0 0 ATGCATGC qqqqqqqq XQ:i:8 XR:i:8 XE:i:57
+r2 0 one 100 20 50M * 0 0 ATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCATGCAT qqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqqq XQ:i:50 XR:i:50 XE:i:149
+unmapped 5 two 200 0 * two 200 0 ATGCATGC qqqqqqqq XQ:i:0 XR:i:0 XE:i:200
+hascigar 5 two 200 0 6M2S two 200 0 ATGCATGC qqqqqqqq XQ:i:8 XR:i:6 XE:i:200
+s1 0 one 300 20 2M * 0 0 AT qq XQ:i:2 XR:i:2 XE:i:301
+su1 4 * 0 0 * * 0 0 AT qq XQ:i:0 XR:i:0 XE:i:0
+su2 5 two 400 0 * two 400 0 AT qq XQ:i:0 XR:i:0 XE:i:400
+su3 4 one 500 0 2M * 0 0 AT qq XQ:i:2 XR:i:2 XE:i:500
--- /dev/null
+##fileformat=VCFv4.3
+##FILTER=<ID=PASS,Description="All filters passed">
+##contig=<ID=1>
+##FORMAT=<ID=S,Number=1,Type=String,Description="Text">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT S1 S2 S3
+1 100 a A T . . . S a bbbbbbb ccccccccc
--- /dev/null
+/* test/hfile.c -- Test cases for low-level input/output streams.
+
+ Copyright (C) 2013-2014 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdarg.h>
+#include <stdio.h>
+#include <stdlib.h>
+#include <errno.h>
+
+#include <sys/stat.h>
+
+#include "htslib/hfile.h"
+#include "htslib/hts_defs.h"
+
+void HTS_NORETURN fail(const char *format, ...)
+{
+ int err = errno;
+ va_list args;
+ va_start(args, format);
+ vfprintf(stderr, format, args);
+ va_end(args);
+ if (err != 0) fprintf(stderr, ": %s", strerror(err));
+ fprintf(stderr, "\n");
+ exit(EXIT_FAILURE);
+}
+
+void check_offset(hFILE *f, off_t off, const char *message)
+{
+ off_t ret = htell(f);
+ if (ret < 0) fail("htell(%s)", message);
+ if (ret == off) return;
+
+ fprintf(stderr, "%s offset incorrect: expected %ld but got %ld\n",
+ message, (long)off, (long)ret);
+ exit(EXIT_FAILURE);
+}
+
+char *slurp(const char *filename)
+{
+ char *text;
+ struct stat sbuf;
+ size_t filesize;
+ FILE *f = fopen(filename, "r");
+ if (f == NULL) fail("fopen(\"%s\", \"r\")", filename);
+ if (fstat(fileno(f), &sbuf) != 0) fail("fstat(\"%s\")", filename);
+ filesize = sbuf.st_size;
+
+ text = (char *) malloc(filesize + 1);
+ if (text == NULL) fail("malloc(text)");
+
+ if (fread(text, 1, filesize, f) != filesize) fail("fread");
+ fclose(f);
+
+ text[filesize] = '\0';
+ return text;
+}
+
+hFILE *fin = NULL;
+hFILE *fout = NULL;
+
+void reopen(const char *infname, const char *outfname)
+{
+ if (fin) { if (hclose(fin) != 0) fail("hclose(input)"); }
+ if (fout) { if (hclose(fout) != 0) fail("hclose(output)"); }
+
+ fin = hopen(infname, "r");
+ if (fin == NULL) fail("hopen(\"%s\")", infname);
+
+ fout = hopen(outfname, "w");
+ if (fout == NULL) fail("hopen(\"%s\")", outfname);
+}
+
+int main(void)
+{
+ static const int size[] = { 1, 13, 403, 999, 30000 };
+
+ char buffer[40000];
+ char *original;
+ int c, i;
+ ssize_t n;
+ off_t off;
+
+ reopen("vcf.c", "test/hfile1.tmp");
+ while ((c = hgetc(fin)) != EOF) {
+ if (hputc(c, fout) == EOF) fail("hputc");
+ }
+ if (herrno(fin)) { errno = herrno(fin); fail("hgetc"); }
+
+ reopen("test/hfile1.tmp", "test/hfile2.tmp");
+ if (hpeek(fin, buffer, 50) < 0) fail("hpeek");
+ while ((n = hread(fin, buffer, 17)) > 0) {
+ if (hwrite(fout, buffer, n) != n) fail("hwrite");
+ }
+ if (n < 0) fail("hread");
+
+ reopen("test/hfile2.tmp", "test/hfile3.tmp");
+ while ((n = hread(fin, buffer, sizeof buffer)) > 0) {
+ if (hwrite(fout, buffer, n) != n) fail("hwrite");
+ if (hpeek(fin, buffer, 700) < 0) fail("hpeek");
+ }
+ if (n < 0) fail("hread");
+
+ reopen("test/hfile3.tmp", "test/hfile4.tmp");
+ i = 0;
+ off = 0;
+ while ((n = hread(fin, buffer, size[i++ % 5])) > 0) {
+ off += n;
+ buffer[n] = '\0';
+ check_offset(fin, off, "pre-peek");
+ if (hputs(buffer, fout) == EOF) fail("hputs");
+ if ((n = hpeek(fin, buffer, size[(i+3) % 5])) < 0) fail("hpeek");
+ check_offset(fin, off, "post-peek");
+ }
+ if (n < 0) fail("hread");
+
+ reopen("test/hfile4.tmp", "test/hfile5.tmp");
+ n = hread(fin, buffer, 200);
+ if (n < 0) fail("hread");
+ else if (n != 200) fail("hread only got %d", (int)n);
+ if (hwrite(fout, buffer, 1000) != 1000) fail("hwrite");
+ check_offset(fin, 200, "input/first200");
+ check_offset(fout, 1000, "output/first200");
+
+ if (hseek(fin, 800, SEEK_CUR) < 0) fail("hseek/cur");
+ check_offset(fin, 1000, "input/seek");
+ for (off = 1000; (n = hread(fin, buffer, sizeof buffer)) > 0; off += n)
+ if (hwrite(fout, buffer, n) != n) fail("hwrite");
+ if (n < 0) fail("hread");
+ check_offset(fin, off, "input/eof");
+ check_offset(fout, off, "output/eof");
+
+ if (hseek(fin, 200, SEEK_SET) < 0) fail("hseek/set");
+ if (hseek(fout, 200, SEEK_SET) < 0) fail("hseek(output)");
+ check_offset(fin, 200, "input/backto200");
+ check_offset(fout, 200, "output/backto200");
+ n = hread(fin, buffer, 800);
+ if (n < 0) fail("hread");
+ else if (n != 800) fail("hread only got %d", (int)n);
+ if (hwrite(fout, buffer, 800) != 800) fail("hwrite");
+ check_offset(fin, 1000, "input/wrote800");
+ check_offset(fout, 1000, "output/wrote800");
+
+ if (hflush(fout) == EOF) fail("hflush");
+
+ original = slurp("vcf.c");
+ for (i = 1; i <= 5; i++) {
+ char *text;
+ sprintf(buffer, "test/hfile%d.tmp", i);
+ text = slurp(buffer);
+ if (strcmp(original, text) != 0) {
+ fprintf(stderr, "%s differs from vcf.c\n", buffer);
+ return EXIT_FAILURE;
+ }
+ free(text);
+ }
+ free(original);
+
+ if (hclose(fin) != 0) fail("hclose(input)");
+ if (hclose(fout) != 0) fail("hclose(output)");
+
+ fout = hopen("test/hfile_chars.tmp", "w");
+ if (fout == NULL) fail("hopen(\"test/hfile_chars.tmp\")");
+ for (i = 0; i < 256; i++)
+ if (hputc(i, fout) != i) fail("chars: hputc (%d)", i);
+ if (hclose(fout) != 0) fail("hclose(test/hfile_chars.tmp)");
+
+ fin = hopen("test/hfile_chars.tmp", "r");
+ if (fin == NULL) fail("hopen(\"test/hfile_chars.tmp\") for reading");
+ for (i = 0; i < 256; i++)
+ if ((c = hgetc(fin)) != i)
+ fail("chars: hgetc (%d = 0x%x) returned %d = 0x%x", i, i, c, c);
+ if ((c = hgetc(fin)) != EOF) fail("chars: hgetc (EOF) returned %d", c);
+ if (hclose(fin) != 0) fail("hclose(test/hfile_chars.tmp) for reading");
+
+ fin = hopen("data:hello, world!\n", "r");
+ if (fin == NULL) fail("hopen(\"data:...\")");
+ n = hread(fin, buffer, 300);
+ if (n < 0) fail("hread");
+ buffer[n] = '\0';
+ if (strcmp(buffer, "hello, world!\n") != 0) fail("hread result");
+ if (hclose(fin) != 0) fail("hclose(\"data:...\")");
+
+ return EXIT_SUCCESS;
+}
--- /dev/null
+##fileformat=VCFv4.3
+##FILTER=<ID=PASS,Description="All filters passed">
+##contig=<ID=3>
+##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA1
+3 50 . A T 0 PASS . GT:GT 2,4:.
+3 60 . T C 0 PASS . GT 0/1
+3 70 . G A 0 PASS . GT:GT 2,4:.
+3 80 . C G 0 PASS . GT:GT 2,4:0/1
--- /dev/null
+##fileformat=VCFv4.3
+##contig=<ID=3>
+##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA1
+3 50 . A T 0 PASS . GT:GT 0/1
+3 60 . T C 0 PASS . GT 0/1
+3 70 . G A 0 PASS . GT:GT 0/1:.
+3 80 . C G 0 PASS . GT:GT 0/1:0/1
--- /dev/null
+/* test/sam.c -- SAM/BAM/CRAM API test cases.
+
+ Copyright (C) 2014-2015 Genome Research Ltd.
+
+ Author: John Marshall <jm18@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdarg.h>
+#include <stdio.h>
+#include <stdlib.h>
+#include <string.h>
+#include <math.h>
+
+// Suppress message for faidx_fetch_nseq(), which we're intentionally testing
+#include "htslib/hts_defs.h"
+#undef HTS_DEPRECATED
+#define HTS_DEPRECATED(message)
+
+#include "htslib/sam.h"
+#include "htslib/faidx.h"
+#include "htslib/kstring.h"
+
+int status;
+
+static void fail(const char *fmt, ...)
+{
+ va_list args;
+
+ fprintf(stderr, "Failed: ");
+ va_start(args, fmt);
+ vfprintf(stderr, fmt, args);
+ va_end(args);
+ fprintf(stderr, "\n");
+
+ status = EXIT_FAILURE;
+}
+
+uint8_t *check_bam_aux_get(const bam1_t *aln, const char *tag, char type)
+{
+ uint8_t *p = bam_aux_get(aln, tag);
+ if (p) {
+ if (*p == type) return p;
+ else fail("%s field of type '%c', expected '%c'\n", tag, *p, type);
+ }
+ else fail("can't find %s field\n", tag);
+
+ return NULL;
+}
+
+#define PI 3.141592653589793
+#define E 2.718281828459045
+#define HELLO "Hello, world!"
+#define BEEF "DEADBEEF"
+
+#define str(x) #x
+#define xstr(x) str(x)
+
+static int aux_fields1(void)
+{
+ static const char sam[] = "data:"
+"@SQ\tSN:one\tLN:1000\n"
+"@SQ\tSN:two\tLN:500\n"
+"r1\t0\tone\t500\t20\t8M\t*\t0\t0\tATGCATGC\tqqqqqqqq\tXA:A:k\tXi:i:37\tXf:f:" xstr(PI) "\tXd:d:" xstr(E) "\tXZ:Z:" HELLO "\tXH:H:" BEEF "\tXB:B:c,-2,0,+2\tZZ:i:1000000\tY1:i:-2147483648\tY2:i:-2147483647\tY3:i:-1\tY4:i:0\tY5:i:1\tY6:i:2147483647\tY7:i:2147483648\tY8:i:4294967295\n";
+
+ // Canonical form of the alignment record above, as output by sam_format1()
+ static const char r1[] = "r1\t0\tone\t500\t20\t8M\t*\t0\t0\tATGCATGC\tqqqqqqqq\tXA:A:k\tXi:i:37\tXf:f:3.14159\tXd:d:2.71828\tXZ:Z:" HELLO "\tXH:H:" BEEF "\tXB:B:c,-2,0,2\tZZ:i:1000000\tY1:i:-2147483648\tY2:i:-2147483647\tY3:i:-1\tY4:i:0\tY5:i:1\tY6:i:2147483647\tY7:i:2147483648\tY8:i:4294967295";
+
+ samFile *in = sam_open(sam, "r");
+ bam_hdr_t *header = sam_hdr_read(in);
+ bam1_t *aln = bam_init1();
+ uint8_t *p;
+ uint32_t n;
+ kstring_t ks = { 0, 0, NULL };
+
+ if (sam_read1(in, header, aln) >= 0) {
+ if ((p = check_bam_aux_get(aln, "XA", 'A')) && bam_aux2A(p) != 'k')
+ fail("XA field is '%c', expected 'k'", bam_aux2A(p));
+
+ if ((p = check_bam_aux_get(aln, "Xi", 'C')) && bam_aux2i(p) != 37)
+ fail("Xi field is %d, expected 37", bam_aux2i(p));
+
+ if ((p = check_bam_aux_get(aln, "Xf", 'f')) && fabs(bam_aux2f(p) - PI) > 1E-6)
+ fail("Xf field is %.12f, expected pi", bam_aux2f(p));
+
+ if ((p = check_bam_aux_get(aln, "Xd", 'd')) && fabs(bam_aux2f(p) - E) > 1E-6)
+ fail("Xf field is %.12f, expected e", bam_aux2f(p));
+
+ if ((p = check_bam_aux_get(aln, "XZ", 'Z')) && strcmp(bam_aux2Z(p), HELLO) != 0)
+ fail("XZ field is \"%s\", expected \"%s\"", bam_aux2Z(p), HELLO);
+
+ if ((p = check_bam_aux_get(aln, "XH", 'H')) && strcmp(bam_aux2Z(p), BEEF) != 0)
+ fail("XH field is \"%s\", expected \"%s\"", bam_aux2Z(p), BEEF);
+
+ // TODO Invent and use bam_aux2B()
+ if ((p = check_bam_aux_get(aln, "XB", 'B')) && ! (memcmp(p, "Bc", 2) == 0 && (memcpy(&n, p+2, 4), n) == 3 && memcmp(p+6, "\xfe\x00\x02", 3) == 0))
+ fail("XB field is %c,..., expected c,-2,0,+2", p[1]);
+
+ if ((p = check_bam_aux_get(aln, "ZZ", 'I')) && bam_aux2i(p) != 1000000)
+ fail("ZZ field is %d, expected 1000000", bam_aux2i(p));
+
+ if ((p = bam_aux_get(aln, "Y1")) && bam_aux2i(p) != -2147483647-1)
+ fail("Y1 field is %d, expected -2^31", bam_aux2i(p));
+
+ if ((p = bam_aux_get(aln, "Y2")) && bam_aux2i(p) != -2147483647)
+ fail("Y2 field is %d, expected -2^31+1", bam_aux2i(p));
+
+ if ((p = bam_aux_get(aln, "Y3")) && bam_aux2i(p) != -1)
+ fail("Y3 field is %d, expected -1", bam_aux2i(p));
+
+ if ((p = bam_aux_get(aln, "Y4")) && bam_aux2i(p) != 0)
+ fail("Y4 field is %d, expected 0", bam_aux2i(p));
+
+ if ((p = bam_aux_get(aln, "Y5")) && bam_aux2i(p) != 1)
+ fail("Y5 field is %d, expected 1", bam_aux2i(p));
+
+ if ((p = bam_aux_get(aln, "Y6")) && bam_aux2i(p) != 2147483647)
+ fail("Y6 field is %d, expected 2^31-1", bam_aux2i(p));
+
+ // TODO Checking these perhaps requires inventing bam_aux2u() or so
+#if 0
+ if ((p = bam_aux_get(aln, "Y7")) && bam_aux2i(p) != 2147483648)
+ fail("Y7 field is %d, expected 2^31", bam_aux2i(p));
+
+ if ((p = bam_aux_get(aln, "Y8")) && bam_aux2i(p) != 4294967295)
+ fail("Y8 field is %d, expected 2^32-1", bam_aux2i(p));
+#endif
+
+ if (sam_format1(header, aln, &ks) < 0)
+ fail("can't format record");
+
+ if (strcmp(ks.s, r1) != 0)
+ fail("record formatted incorrectly: \"%s\"", ks.s);
+
+ free(ks.s);
+ }
+ else fail("can't read record");
+
+ bam_destroy1(aln);
+ bam_hdr_destroy(header);
+ sam_close(in);
+
+ return 1;
+}
+
+static void iterators1(void)
+{
+ hts_itr_destroy(sam_itr_queryi(NULL, HTS_IDX_REST, 0, 0));
+ hts_itr_destroy(sam_itr_queryi(NULL, HTS_IDX_NONE, 0, 0));
+}
+
+static void faidx1(const char *filename)
+{
+ int n, n_exp = 0;
+ char tmpfilename[FILENAME_MAX], line[500];
+ FILE *fin, *fout;
+ faidx_t *fai;
+
+ fin = fopen(filename, "r");
+ if (fin == NULL) fail("can't open %s\n", filename);
+ sprintf(tmpfilename, "%s.tmp", filename);
+ fout = fopen(tmpfilename, "w");
+ if (fout == NULL) fail("can't create temporary %s\n", tmpfilename);
+ while (fgets(line, sizeof line, fin)) {
+ if (line[0] == '>') n_exp++;
+ fputs(line, fout);
+ }
+ fclose(fin);
+ fclose(fout);
+
+ if (fai_build(tmpfilename) < 0) fail("can't index %s", tmpfilename);
+ fai = fai_load(tmpfilename);
+ if (fai == NULL) fail("can't load faidx file %s", tmpfilename);
+
+ n = faidx_fetch_nseq(fai);
+ if (n != n_exp)
+ fail("%s: faidx_fetch_nseq returned %d, expected %d", filename, n, n_exp);
+
+ n = faidx_nseq(fai);
+ if (n != n_exp)
+ fail("%s: faidx_nseq returned %d, expected %d", filename, n, n_exp);
+
+ fai_destroy(fai);
+}
+
+int main(int argc, char **argv)
+{
+ int i;
+
+ status = EXIT_SUCCESS;
+
+ aux_fields1();
+ iterators1();
+ for (i = 1; i < argc; i++) faidx1(argv[i]);
+
+ return status;
+}
--- /dev/null
+/* test/test-regidx.c -- Regions index test harness.
+
+ Copyright (C) 2014 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+ Permission is hereby granted, free of charge, to any person obtaining a copy
+ of this software and associated documentation files (the "Software"), to deal
+ in the Software without restriction, including without limitation the rights
+ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+ copies of the Software, and to permit persons to whom the Software is
+ furnished to do so, subject to the following conditions:
+
+ The above copyright notice and this permission notice shall be included in
+ all copies or substantial portions of the Software.
+
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+ IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+ FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+ AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+ LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+ OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
+ THE SOFTWARE.
+*/
+
+#include <config.h>
+
+#include <stdarg.h>
+#include <stdlib.h>
+#include <stdio.h>
+#include <ctype.h>
+#include <string.h>
+#include <htslib/regidx.h>
+
+void error(const char *format, ...)
+{
+ va_list ap;
+ va_start(ap, format);
+ vfprintf(stderr, format, ap);
+ va_end(ap);
+ exit(-1);
+}
+
+int custom_parse(const char *line, char **chr_beg, char **chr_end, reg_t *reg, void *payload, void *usr)
+{
+ // Use the standard parser for CHROM,FROM,TO
+ int i, ret = regidx_parse_tab(line,chr_beg,chr_end,reg,NULL,NULL);
+ if ( ret!=0 ) return ret;
+
+ // Skip the fields that were parsed above
+ char *ss = (char*) line;
+ while ( *ss && isspace(*ss) ) ss++;
+ for (i=0; i<3; i++)
+ {
+ while ( *ss && !isspace(*ss) ) ss++;
+ if ( !*ss ) return -2; // wrong number of fields
+ while ( *ss && isspace(*ss) ) ss++;
+ }
+ if ( !*ss ) return -2;
+
+ // Parse the payload
+ char *se = ss;
+ while ( *se && !isspace(*se) ) se++;
+ char **dat = (char**) payload;
+ *dat = (char*) malloc(se-ss+1);
+ memcpy(*dat,ss,se-ss+1);
+ (*dat)[se-ss] = 0;
+ return 0;
+}
+void custom_free(void *payload)
+{
+ char **dat = (char**)payload;
+ free(*dat);
+}
+
+int main(int argc, char **argv)
+{
+ // Init index with no file name, we will insert the regions manually
+ regidx_t *idx = regidx_init(NULL,custom_parse,custom_free,sizeof(char*),NULL);
+ if ( !idx ) error("init failed\n");
+
+ // Insert regions
+ char *line;
+ line = "1 10000000 10000000 1:10000000-10000000"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line);
+ line = "1 20000000 20000001 1:20000000-20000001"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line);
+ line = "1 20000002 20000002 1:20000002-20000002"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line);
+ line = "1 30000000 30000000 1:30000000-30000000"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line);
+
+ // Finish initialization
+ regidx_insert(idx,NULL);
+
+ // Test
+ regitr_t itr;
+ int from, to;
+
+ from = to = 10000000;
+ if ( !regidx_overlap(idx,"1",from-1,to-1,&itr) ) error("query failed: 1:%d-%d\n",from,to);
+ if ( strcmp("1:10000000-10000000",REGITR_PAYLOAD(itr,char*)) ) error("query failed: 1:%d-%d vs %s\n", from,to,REGITR_PAYLOAD(itr,char*));
+ if ( !regidx_overlap(idx,"1",from-2,to-1,&itr) ) error("query failed: 1:%d-%d\n",from-1,to);
+ if ( !regidx_overlap(idx,"1",from-2,to+3,&itr) ) error("query failed: 1:%d-%d\n",from-1,to+2);
+ if ( regidx_overlap(idx,"1",from-2,to-2,&itr) ) error("query failed: 1:%d-%d\n",from-1,to-1);
+
+ from = to = 20000000;
+ if ( !regidx_overlap(idx,"1",from-1,to-1,&itr) ) error("query failed: 1:%d-%d\n",from,to);
+
+ from = to = 20000002;
+ if ( !regidx_overlap(idx,"1",from-1,to-1,&itr) ) error("query failed: 1:%d-%d\n",from,to);
+
+ from = to = 30000000;
+ if ( !regidx_overlap(idx,"1",from-1,to-1,&itr) ) error("query failed: 1:%d-%d\n",from,to);
+
+ // Clean up
+ regidx_destroy(idx);
+
+ return 0;
+}
+
+
--- /dev/null
+/* test/test-vcf-api.c -- VCF test harness.
+
+ Copyright (C) 2013, 2014 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <htslib/hts.h>
+#include <htslib/vcf.h>
+#include <htslib/kstring.h>
+#include <htslib/kseq.h>
+
+void write_bcf(char *fname)
+{
+ // Init
+ htsFile *fp = hts_open(fname,"wb");
+ bcf_hdr_t *hdr = bcf_hdr_init("w");
+ bcf1_t *rec = bcf_init1();
+
+ // Create VCF header
+ kstring_t str = {0,0,0};
+ bcf_hdr_append(hdr, "##fileDate=20090805");
+ bcf_hdr_append(hdr, "##FORMAT=<ID=UF,Number=1,Type=Integer,Description=\"Unused FORMAT\">");
+ bcf_hdr_append(hdr, "##INFO=<ID=UI,Number=1,Type=Integer,Description=\"Unused INFO\">");
+ bcf_hdr_append(hdr, "##FILTER=<ID=Flt,Description=\"Unused FILTER\">");
+ bcf_hdr_append(hdr, "##unused=<XX=AA,Description=\"Unused generic\">");
+ bcf_hdr_append(hdr, "##unused=unformatted text 1");
+ bcf_hdr_append(hdr, "##unused=unformatted text 2");
+ bcf_hdr_append(hdr, "##contig=<ID=Unused,length=62435964>");
+ bcf_hdr_append(hdr, "##source=myImputationProgramV3.1");
+ bcf_hdr_append(hdr, "##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta");
+ bcf_hdr_append(hdr, "##contig=<ID=20,length=62435964,assembly=B36,md5=f126cdf8a6e0c7f379d618ff66beb2da,species=\"Homo sapiens\",taxonomy=x>");
+ bcf_hdr_append(hdr, "##phasing=partial");
+ bcf_hdr_append(hdr, "##INFO=<ID=NS,Number=1,Type=Integer,Description=\"Number of Samples With Data\">");
+ bcf_hdr_append(hdr, "##INFO=<ID=DP,Number=1,Type=Integer,Description=\"Total Depth\">");
+ bcf_hdr_append(hdr, "##INFO=<ID=AF,Number=A,Type=Float,Description=\"Allele Frequency\">");
+ bcf_hdr_append(hdr, "##INFO=<ID=AA,Number=1,Type=String,Description=\"Ancestral Allele\">");
+ bcf_hdr_append(hdr, "##INFO=<ID=DB,Number=0,Type=Flag,Description=\"dbSNP membership, build 129\">");
+ bcf_hdr_append(hdr, "##INFO=<ID=H2,Number=0,Type=Flag,Description=\"HapMap2 membership\">");
+ bcf_hdr_append(hdr, "##FILTER=<ID=q10,Description=\"Quality below 10\">");
+ bcf_hdr_append(hdr, "##FILTER=<ID=s50,Description=\"Less than 50% of samples have data\">");
+ bcf_hdr_append(hdr, "##FORMAT=<ID=GT,Number=1,Type=String,Description=\"Genotype\">");
+ bcf_hdr_append(hdr, "##FORMAT=<ID=GQ,Number=1,Type=Integer,Description=\"Genotype Quality\">");
+ bcf_hdr_append(hdr, "##FORMAT=<ID=DP,Number=1,Type=Integer,Description=\"Read Depth\">");
+ bcf_hdr_append(hdr, "##FORMAT=<ID=HQ,Number=2,Type=Integer,Description=\"Haplotype Quality\">");
+ bcf_hdr_append(hdr, "##FORMAT=<ID=TS,Number=1,Type=String,Description=\"Test String\">");
+
+ bcf_hdr_add_sample(hdr, "NA00001");
+ bcf_hdr_add_sample(hdr, "NA00002");
+ bcf_hdr_add_sample(hdr, "NA00003");
+ bcf_hdr_add_sample(hdr, NULL); // to update internal structures
+ bcf_hdr_write(fp, hdr);
+
+
+ // Add a record
+ // 20 14370 rs6054257 G A 29 PASS NS=3;DP=14;AF=0.5;DB;H2 GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,.
+ // .. CHROM
+ rec->rid = bcf_hdr_name2id(hdr, "20");
+ // .. POS
+ rec->pos = 14369;
+ // .. ID
+ bcf_update_id(hdr, rec, "rs6054257");
+ // .. REF and ALT
+ bcf_update_alleles_str(hdr, rec, "G,A");
+ // .. QUAL
+ rec->qual = 29;
+ // .. FILTER
+ int32_t tmpi = bcf_hdr_id2int(hdr, BCF_DT_ID, "PASS");
+ bcf_update_filter(hdr, rec, &tmpi, 1);
+ // .. INFO
+ tmpi = 3;
+ bcf_update_info_int32(hdr, rec, "NS", &tmpi, 1);
+ tmpi = 14;
+ bcf_update_info_int32(hdr, rec, "DP", &tmpi, 1);
+ float tmpf = 0.5;
+ bcf_update_info_float(hdr, rec, "AF", &tmpf, 1);
+ bcf_update_info_flag(hdr, rec, "DB", NULL, 1);
+ bcf_update_info_flag(hdr, rec, "H2", NULL, 1);
+ // .. FORMAT
+ int32_t *tmpia = (int*)malloc(bcf_hdr_nsamples(hdr)*2*sizeof(int));
+ tmpia[0] = bcf_gt_phased(0);
+ tmpia[1] = bcf_gt_phased(0);
+ tmpia[2] = bcf_gt_phased(1);
+ tmpia[3] = bcf_gt_phased(0);
+ tmpia[4] = bcf_gt_unphased(1);
+ tmpia[5] = bcf_gt_unphased(1);
+ bcf_update_genotypes(hdr, rec, tmpia, bcf_hdr_nsamples(hdr)*2);
+ tmpia[0] = 48;
+ tmpia[1] = 48;
+ tmpia[2] = 43;
+ bcf_update_format_int32(hdr, rec, "GQ", tmpia, bcf_hdr_nsamples(hdr));
+ tmpia[0] = 1;
+ tmpia[1] = 8;
+ tmpia[2] = 5;
+ bcf_update_format_int32(hdr, rec, "DP", tmpia, bcf_hdr_nsamples(hdr));
+ tmpia[0] = 51;
+ tmpia[1] = 51;
+ tmpia[2] = 51;
+ tmpia[3] = 51;
+ tmpia[4] = bcf_int32_missing;
+ tmpia[5] = bcf_int32_missing;
+ bcf_update_format_int32(hdr, rec, "HQ", tmpia, bcf_hdr_nsamples(hdr)*2);
+ char *tmp_str[] = {"String1","SomeOtherString2","YetAnotherString3"};
+ bcf_update_format_string(hdr, rec, "TS", (const char**)tmp_str, 3);
+ bcf_write1(fp, hdr, rec);
+
+ // 20 1110696 . A G,T 67 . NS=2;DP=10;AF=0.333,.;AA=T;DB GT 2 1 ./.
+ bcf_clear1(rec);
+ rec->rid = bcf_hdr_name2id(hdr, "20");
+ rec->pos = 1110695;
+ bcf_update_alleles_str(hdr, rec, "A,G,T");
+ rec->qual = 67;
+ tmpi = 2;
+ bcf_update_info_int32(hdr, rec, "NS", &tmpi, 1);
+ tmpi = 10;
+ bcf_update_info_int32(hdr, rec, "DP", &tmpi, 1);
+ float *tmpfa = (float*)malloc(2*sizeof(float));
+ tmpfa[0] = 0.333;
+ bcf_float_set_missing(tmpfa[1]);
+ bcf_update_info_float(hdr, rec, "AF", tmpfa, 2);
+ bcf_update_info_string(hdr, rec, "AA", "T");
+ bcf_update_info_flag(hdr, rec, "DB", NULL, 1);
+ tmpia[0] = bcf_gt_phased(2);
+ tmpia[1] = bcf_int32_vector_end;
+ tmpia[2] = bcf_gt_phased(1);
+ tmpia[3] = bcf_int32_vector_end;
+ tmpia[4] = bcf_gt_missing;
+ tmpia[5] = bcf_gt_missing;
+ bcf_update_genotypes(hdr, rec, tmpia, bcf_hdr_nsamples(hdr)*2);
+ bcf_write1(fp, hdr, rec);
+
+ free(tmpia);
+ free(tmpfa);
+
+ // Clean
+ free(str.s);
+ bcf_destroy1(rec);
+ bcf_hdr_destroy(hdr);
+ int ret;
+ if ( (ret=hts_close(fp)) )
+ {
+ fprintf(stderr,"hts_close(%s): non-zero status %d\n",fname,ret);
+ exit(ret);
+ }
+}
+
+void bcf_to_vcf(char *fname)
+{
+ htsFile *fp = hts_open(fname,"rb");
+ bcf_hdr_t *hdr = bcf_hdr_read(fp);
+ bcf1_t *rec = bcf_init1();
+
+ char *gz_fname = (char*) malloc(strlen(fname)+4);
+ snprintf(gz_fname,strlen(fname)+4,"%s.gz",fname);
+ htsFile *out = hts_open(gz_fname,"wg");
+
+ bcf_hdr_t *hdr_out = bcf_hdr_dup(hdr);
+ bcf_hdr_remove(hdr_out,BCF_HL_STR,"unused");
+ bcf_hdr_remove(hdr_out,BCF_HL_GEN,"unused");
+ bcf_hdr_remove(hdr_out,BCF_HL_FLT,"Flt");
+ bcf_hdr_remove(hdr_out,BCF_HL_INFO,"UI");
+ bcf_hdr_remove(hdr_out,BCF_HL_FMT,"UF");
+ bcf_hdr_remove(hdr_out,BCF_HL_CTG,"Unused");
+ bcf_hdr_write(out, hdr_out);
+
+ while ( bcf_read1(fp, hdr, rec)>=0 )
+ {
+ bcf_write1(out, hdr_out, rec);
+
+ // Test problems caused by bcf1_sync: the data block
+ // may be realloced, also the unpacked structures must
+ // get updated.
+ bcf_unpack(rec, BCF_UN_STR);
+ bcf_update_id(hdr, rec, 0);
+ bcf_update_format_int32(hdr, rec, "GQ", NULL, 0);
+
+ bcf1_t *dup = bcf_dup(rec); // force bcf1_sync call
+ bcf_write1(out, hdr_out, dup);
+ bcf_destroy1(dup);
+
+ bcf_update_alleles_str(hdr_out, rec, "G,A");
+ int32_t tmpi = 99;
+ bcf_update_info_int32(hdr_out, rec, "DP", &tmpi, 1);
+ int32_t tmpia[] = {9,9,9};
+ bcf_update_format_int32(hdr_out, rec, "DP", tmpia, 3);
+
+ bcf_write1(out, hdr_out, rec);
+ }
+
+ bcf_destroy1(rec);
+ bcf_hdr_destroy(hdr);
+ bcf_hdr_destroy(hdr_out);
+ int ret;
+ if ( (ret=hts_close(fp)) )
+ {
+ fprintf(stderr,"hts_close(%s): non-zero status %d\n",fname,ret);
+ exit(ret);
+ }
+ if ( (ret=hts_close(out)) )
+ {
+ fprintf(stderr,"hts_close(%s): non-zero status %d\n",gz_fname,ret);
+ exit(ret);
+ }
+
+
+ // read gzip, write stdout
+ htsFile *gz_in = hts_open(gz_fname, "r");
+ if ( !gz_in )
+ {
+ fprintf(stderr,"Could not read: %s\n", gz_fname);
+ exit(1);
+ }
+
+ kstring_t line = {0,0,0};
+ while ( hts_getline(gz_in, KS_SEP_LINE, &line)>0 )
+ {
+ kputc('\n',&line);
+ fwrite(line.s,1,line.l,stdout);
+ }
+
+ if ( (ret=hts_close(gz_in)) )
+ {
+ fprintf(stderr,"hts_close(%s): non-zero status %d\n",gz_fname,ret);
+ exit(ret);
+ }
+ free(line.s);
+ free(gz_fname);
+}
+
+void iterator(const char *fname)
+{
+ htsFile *fp = hts_open(fname, "r");
+ bcf_hdr_t *hdr = bcf_hdr_read(fp);
+ hts_idx_t *idx;
+ hts_itr_t *iter;
+
+ bcf_index_build(fname, 0);
+ idx = bcf_index_load(fname);
+
+ iter = bcf_itr_queryi(idx, bcf_hdr_name2id(hdr, "20"), 1110600, 1110800);
+ bcf_itr_destroy(iter);
+
+ iter = bcf_itr_querys(idx, hdr, "20:1110600-1110800");
+ bcf_itr_destroy(iter);
+
+ hts_idx_destroy(idx);
+ bcf_hdr_destroy(hdr);
+ int ret;
+ if ( (ret=hts_close(fp)) )
+ {
+ fprintf(stderr,"hts_close(%s): non-zero status %d\n",fname,ret);
+ exit(ret);
+ }
+}
+
+int main(int argc, char **argv)
+{
+ char *fname = argc>1 ? argv[1] : "rmme.bcf";
+ write_bcf(fname);
+ bcf_to_vcf(fname);
+ iterator(fname);
+ return 0;
+}
+
--- /dev/null
+##fileformat=VCFv4.2
+##FILTER=<ID=PASS,Description="All filters passed">
+##fileDate=20090805
+##unused=<XX=AA,Description="Unused generic">
+##source=myImputationProgramV3.1
+##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta
+##contig=<ID=20,length=62435964,assembly=B36,md5=f126cdf8a6e0c7f379d618ff66beb2da,species="Homo sapiens",taxonomy=x>
+##phasing=partial
+##INFO=<ID=NS,Number=1,Type=Integer,Description="Number of Samples With Data">
+##INFO=<ID=DP,Number=1,Type=Integer,Description="Total Depth">
+##INFO=<ID=AF,Number=A,Type=Float,Description="Allele Frequency">
+##INFO=<ID=AA,Number=1,Type=String,Description="Ancestral Allele">
+##INFO=<ID=DB,Number=0,Type=Flag,Description="dbSNP membership, build 129">
+##INFO=<ID=H2,Number=0,Type=Flag,Description="HapMap2 membership">
+##FILTER=<ID=q10,Description="Quality below 10">
+##FILTER=<ID=s50,Description="Less than 50% of samples have data">
+##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
+##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="Genotype Quality">
+##FORMAT=<ID=DP,Number=1,Type=Integer,Description="Read Depth">
+##FORMAT=<ID=HQ,Number=2,Type=Integer,Description="Haplotype Quality">
+##FORMAT=<ID=TS,Number=1,Type=String,Description="Test String">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003
+20 14370 rs6054257 G A 29 PASS NS=3;DP=14;AF=0.5;DB;H2 GT:GQ:DP:HQ:TS 0|0:48:1:51,51:String1 1|0:48:8:51,51:SomeOtherString2 1/1:43:5:.,.:YetAnotherString3
+20 14370 . G A 29 PASS NS=3;DP=14;AF=0.5;DB;H2 GT:DP:HQ:TS 0|0:1:51,51:String1 1|0:8:51,51:SomeOtherString2 1/1:5:.,.:YetAnotherString3
+20 14370 . G A 29 PASS NS=3;DP=99;AF=0.5;DB;H2 GT:DP:HQ:TS 0|0:9:51,51:String1 1|0:9:51,51:SomeOtherString2 1/1:9:.,.:YetAnotherString3
+20 1110696 . A G,T 67 . NS=2;DP=10;AF=0.333,.;AA=T;DB GT 2 1 ./.
+20 1110696 . A G,T 67 . NS=2;DP=10;AF=0.333,.;AA=T;DB GT 2 1 ./.
+20 1110696 . G A 67 . NS=2;DP=99;AF=0.333,.;AA=T;DB GT:DP 2:9 1:9 ./.:9
--- /dev/null
+##fileformat=VCFv4.1
+##fileDate=20150126
+##reference=hs37d5
+##phasing=partial
+##FILTER=<ID=INDEL_SPECIFIC_FILTERS,Description="QD < 2.0 || ReadPosRankSum < -20.0 || InbreedingCoeff < -0.8 || FS > 200.0">
+##FILTER=<ID=LowQual,Description="Low quality">
+##FILTER=<ID=VQSRTrancheSNP99.00to99.90,Description="Truth sensitivity tranche level for SNP model at VQS Lod: -6.6778 <= x < -0.6832">
+##FILTER=<ID=VQSRTrancheSNP99.90to100.00+,Description="Truth sensitivity tranche level for SNP model at VQS Lod < -36469.5723">
+##INFO=<ID=TRAILING,Number=.,Type=Integer,Description="This line contains trailing spaces for testing purposes">
+##FORMAT=<ID=AD,Number=.,Type=Integer,Description="Allelic depths for the ref and alt alleles in the order listed">
+##FORMAT=<ID=DP,Number=1,Type=Integer,Description="Approximate read depth (reads with MQ=255 or with bad mates are filtered)">
+##FORMAT=<ID=GQ,Number=1,Type=Integer,EmptyWithSpace= ,Description="Genotype Quality">
+##FORMAT=<ID=GATK,Number=1, Type = String , Description="Genotype as called by GATK. Always a diploid call. All other genotype stats based on this genotype.">
+##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype after Personalis post-processing to match detected chromosome counts.">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001
+1 12065947 PTV001 C T,A 29 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:19
+1 109817590 PTV002 G T 77 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:20
+1 153791300 PTV003 CTG C 81 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:21
+1 156104666 PTV004 TTGAGAGCCGGCTGGCGGAT TCC 30 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:22
+1 156108541 PTV005 G GG 31 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:23
+1 161279695 PTV006 T C,A 32 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:24
+1 169519049 PTV007 T . 35 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:24
+1 226125468 PTV097 G A 99 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:109
+16 2103394 PTV056 C T 68 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:72
+4 31789170 PTV021 G . 77 PASS . GT:GATK:AD:DP:GQ 0/1:0/1:3,2:5:38
--- /dev/null
+##fileformat=VCFv4.1
+##FILTER=<ID=PASS,Description="All filters passed">
+##fileDate=20150126
+##reference=hs37d5
+##phasing=partial
+##FILTER=<ID=INDEL_SPECIFIC_FILTERS,Description="QD < 2.0 || ReadPosRankSum < -20.0 || InbreedingCoeff < -0.8 || FS > 200.0">
+##FILTER=<ID=LowQual,Description="Low quality">
+##FILTER=<ID=VQSRTrancheSNP99.00to99.90,Description="Truth sensitivity tranche level for SNP model at VQS Lod: -6.6778 <= x < -0.6832">
+##FILTER=<ID=VQSRTrancheSNP99.90to100.00+,Description="Truth sensitivity tranche level for SNP model at VQS Lod < -36469.5723">
+##INFO=<ID=TRAILING,Number=.,Type=Integer,Description="This line contains trailing spaces for testing purposes">
+##FORMAT=<ID=AD,Number=.,Type=Integer,Description="Allelic depths for the ref and alt alleles in the order listed">
+##FORMAT=<ID=DP,Number=1,Type=Integer,Description="Approximate read depth (reads with MQ=255 or with bad mates are filtered)">
+##FORMAT=<ID=GQ,Number=1,Type=Integer,EmptyWithSpace=,Description="Genotype Quality">
+##FORMAT=<ID=GATK,Number=1,Type=String,Description="Genotype as called by GATK. Always a diploid call. All other genotype stats based on this genotype.">
+##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype after Personalis post-processing to match detected chromosome counts.">
+#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001
--- /dev/null
+/* test/test-vcf-sweep.c -- VCF test harness.
+
+ Copyright (C) 2013 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <htslib/vcf_sweep.h>
+
+int main(int argc, char **argv)
+{
+ if ( argc!=2 )
+ {
+ fprintf(stderr,"Usage: test-vcf-sweep <file.bcf|file.vcf>\n");
+ return 1;
+ }
+
+ // Init variables. The checksum is just for this test program to output
+ // something and verify that all sites are read in both passes - fwd and
+ // bwd.
+ bcf_sweep_t *sw = bcf_sweep_init(argv[1]);
+ bcf_hdr_t *hdr = bcf_sweep_hdr(sw);
+ int chksum = 0;
+
+ // First we must sweep forward and read the whole file to build an index.
+ // If this is undesirable, we can require the presence of a .gzi index
+ // which can be created with `bgzip -r` from the samtools/htslib package
+ bcf1_t *rec;
+ while ( (rec = bcf_sweep_fwd(sw)) ) chksum += rec->pos+1;
+ printf("fwd position chksum: %d\n", chksum);
+
+ // Now sweep backward.
+ chksum = 0;
+ while ( (rec = bcf_sweep_bwd(sw)) ) chksum += rec->pos+1;
+ printf("bwd position chksum: %d\n", chksum);
+
+ // And forward and backward again, this time summing the PL vectors
+ int i,j, mPLs = 0, nPLs;
+ int32_t *PLs = NULL;
+ chksum = 0;
+ while ( (rec = bcf_sweep_fwd(sw)) )
+ {
+ // get copy of the PL vectors
+ nPLs = bcf_get_format_int32(hdr, rec, "PL", &PLs, &mPLs);
+ if ( !nPLs ) continue; // PL not present
+
+ // how many values are there per sample
+ int nvals = nPLs / bcf_hdr_nsamples(hdr);
+
+ int32_t *ptr = PLs;
+ for (i=0; i<bcf_hdr_nsamples(hdr); i++)
+ {
+ for (j=0; j<nvals; j++)
+ {
+ // check for shorter vectors (haploid genotypes amongst diploids)
+ if ( ptr[j]==bcf_int32_vector_end ) break;
+
+ // skip missing values
+ if ( ptr[j]==bcf_int32_missing ) continue;
+
+ chksum += ptr[j];
+ }
+ ptr += nvals;
+ }
+ }
+ printf("fwd PL chksum: %d\n", chksum);
+
+ // And the same backwards..
+ chksum = 0;
+ while ( (rec = bcf_sweep_bwd(sw)) )
+ {
+ nPLs = bcf_get_format_int32(hdr, rec, "PL", &PLs, &mPLs);
+ if ( !nPLs ) continue;
+ int nvals = nPLs / bcf_hdr_nsamples(hdr);
+ int32_t *ptr = PLs;
+ for (i=0; i<bcf_hdr_nsamples(hdr); i++)
+ {
+ for (j=0; j<nvals; j++)
+ {
+ if ( ptr[j]==bcf_int32_vector_end ) break;
+ if ( ptr[j]==bcf_int32_missing ) continue;
+ chksum += ptr[j];
+ }
+ ptr += nvals;
+ }
+ }
+ printf("bwd PL chksum: %d\n", chksum);
+
+ // Clean up
+ bcf_sweep_destroy(sw);
+ return 0;
+}
+
+
--- /dev/null
+fwd position chksum: 1125066
+bwd position chksum: 1125066
+fwd PL chksum: 0
+bwd PL chksum: 0
--- /dev/null
+#!/usr/bin/env perl
+#
+# Copyright (C) 2012-2013 Genome Research Ltd.
+#
+# Author: Petr Danecek <pd3@sanger.ac.uk>
+#
+# Permission is hereby granted, free of charge, to any person obtaining a copy
+# of this software and associated documentation files (the "Software"), to deal
+# in the Software without restriction, including without limitation the rights
+# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+# copies of the Software, and to permit persons to whom the Software is
+# furnished to do so, subject to the following conditions:
+#
+# The above copyright notice and this permission notice shall be included in
+# all copies or substantial portions of the Software.
+#
+# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+# DEALINGS IN THE SOFTWARE.
+
+use strict;
+use warnings;
+use Carp;
+use FindBin;
+use lib "$FindBin::Bin";
+use Getopt::Long;
+use File::Temp qw/ tempfile tempdir /;
+use IO::Handle;
+
+my $opts = parse_params();
+
+test_view($opts);
+test_vcf_api($opts,out=>'test-vcf-api.out');
+test_vcf_sweep($opts,out=>'test-vcf-sweep.out');
+test_vcf_various($opts);
+test_convert_padded_header($opts);
+
+print "\nNumber of tests:\n";
+printf " total .. %d\n", $$opts{nok}+$$opts{nfailed};
+printf " passed .. %d\n", $$opts{nok};
+printf " failed .. %d\n", $$opts{nfailed};
+print "\n";
+
+exit ($$opts{nfailed} > 0);
+
+#--------------------
+
+sub error
+{
+ my (@msg) = @_;
+ if ( scalar @msg ) { confess @msg; }
+ print
+ "About: samtools/htslib consistency test script\n",
+ "Usage: test.pl [OPTIONS]\n",
+ "Options:\n",
+ " -r, --redo-outputs Recreate expected output files.\n",
+ " -t, --temp-dir <path> When given, temporary files will not be removed.\n",
+ " -h, -?, --help This help message.\n",
+ "\n";
+ exit 1;
+}
+sub parse_params
+{
+ my $opts = { keep_files=>0, nok=>0, nfailed=>0 };
+ my $help;
+ Getopt::Long::Configure('bundling');
+ my $ret = GetOptions (
+ 't|temp-dir:s' => \$$opts{keep_files},
+ 'r|redo-outputs' => \$$opts{redo_outputs},
+ 'h|?|help' => \$help
+ );
+ if ( !$ret or $help ) { error(); }
+ $$opts{tmp} = $$opts{keep_files} ? $$opts{keep_files} : tempdir(CLEANUP=>1);
+ if ( $$opts{keep_files} ) { cmd("mkdir -p $$opts{keep_files}"); }
+ $$opts{path} = $FindBin::RealBin;
+ $$opts{bin} = $FindBin::RealBin;
+ $$opts{bin} =~ s{/test/?$}{};
+ return $opts;
+}
+sub _cmd
+{
+ my ($cmd) = @_;
+ my $kid_io;
+ my @out;
+ my $pid = open($kid_io, "-|");
+ if ( !defined $pid ) { error("Cannot fork: $!"); }
+ if ($pid)
+ {
+ # parent
+ @out = <$kid_io>;
+ close($kid_io);
+ }
+ else
+ {
+ # child
+ exec('bash', '-o','pipefail','-c', $cmd) or error("Cannot execute the command [/bin/sh -o pipefail -c $cmd]: $!");
+ }
+ return ($? >> 8, join('',@out));
+}
+sub cmd
+{
+ my ($cmd) = @_;
+ my ($ret,$out) = _cmd($cmd);
+ if ( $ret ) { error("The command failed [$ret]: $cmd\n", $out); }
+ return $out;
+}
+sub test_cmd
+{
+ my ($opts,%args) = @_;
+ if ( !exists($args{out}) )
+ {
+ if ( !exists($args{in}) ) { error("FIXME: expected out or in key\n"); }
+ $args{out} = "$args{in}.out";
+ }
+ my ($package, $filename, $line, $test)=caller(1);
+ $test =~ s/^.+:://;
+
+ print "$test:\n";
+ print "\t$args{cmd}\n";
+
+ my ($ret,$out) = _cmd("$args{cmd} 2>&1");
+ if ( $ret ) { failed($opts,$test); return; }
+ if ( $$opts{redo_outputs} && -e "$$opts{path}/$args{out}" )
+ {
+ rename("$$opts{path}/$args{out}","$$opts{path}/$args{out}.old");
+ open(my $fh,'>',"$$opts{path}/$args{out}") or error("$$opts{path}/$args{out}: $!");
+ print $fh $out;
+ close($fh);
+ my ($ret,$out) = _cmd("diff -q $$opts{path}/$args{out} $$opts{path}/$args{out}.old");
+ if ( !$ret && $out eq '' ) { unlink("$$opts{path}/$args{out}.old"); }
+ else
+ {
+ print "\tthe expected output changed, saving:\n";
+ print "\t old .. $$opts{path}/$args{out}.old\n";
+ print "\t new .. $$opts{path}/$args{out}\n";
+ }
+ }
+ my $exp = '';
+ if ( open(my $fh,'<',"$$opts{path}/$args{out}") )
+ {
+ my @exp = <$fh>;
+ $exp = join('',@exp);
+ close($fh);
+ }
+ elsif ( !$$opts{redo_outputs} ) { failed($opts,$test,"$$opts{path}/$args{out}: $!"); return; }
+
+ if ( $exp ne $out )
+ {
+ open(my $fh,'>',"$$opts{path}/$args{out}.new") or error("$$opts{path}/$args{out}.new");
+ print $fh $out;
+ close($fh);
+ if ( !-e "$$opts{path}/$args{out}" )
+ {
+ rename("$$opts{path}/$args{out}.new","$$opts{path}/$args{out}") or error("rename $$opts{path}/$args{out}.new $$opts{path}/$args{out}: $!");
+ print "\tthe file with expected output does not exist, creating new one:\n";
+ print "\t\t$$opts{path}/$args{out}\n";
+ }
+ else
+ {
+ failed($opts,$test,"The outputs differ:\n\t\t$$opts{path}/$args{out}\n\t\t$$opts{path}/$args{out}.new");
+ }
+ return;
+ }
+ passed($opts,$test);
+}
+sub failed
+{
+ my ($opts,$test,$reason) = @_;
+ $$opts{nfailed}++;
+ print "\n";
+ STDOUT->flush();
+ if ( defined $reason ) { print STDERR "\t$reason\n"; }
+ print STDERR ".. failed ...\n\n";
+ STDERR->flush();
+}
+sub passed
+{
+ my ($opts,$test) = @_;
+ $$opts{nok}++;
+ print ".. ok\n\n";
+}
+sub is_file_newer
+{
+ my ($afile,$bfile) = @_;
+ my (@astat) = stat($afile) or return 0;
+ my (@bstat) = stat($bfile) or return 0;
+ if ( $astat[9]>$bstat[9] ) { return 1 }
+ return 0;
+}
+
+
+# The tests --------------------------
+
+my $test_view_failures;
+sub testv {
+ my ($cmd) = @_;
+ print " $cmd\n";
+ my ($ret, $out) = _cmd($cmd);
+ if ($ret != 0) {
+ STDOUT->flush();
+ print STDERR "FAILED\n\n";
+ STDERR->flush();
+ $test_view_failures++;
+ }
+}
+
+sub test_view
+{
+ my ($opts, %args) = @_;
+
+ foreach my $sam (glob("*#*.sam")) {
+ my ($base, $ref) = ($sam =~ /((.*)#.*)\.sam/);
+ $ref .= ".fa";
+
+ my $bam = "$base.tmp.bam";
+ my $cram = "$base.tmp.cram";
+
+ print "test_view testing $sam, ref $ref:\n";
+ $test_view_failures = 0;
+
+ # SAM -> BAM -> SAM
+ testv "./test_view -S -b $sam > $bam";
+ testv "./test_view $bam > $bam.sam_";
+ testv "./compare_sam.pl $sam $bam.sam_";
+
+ # SAM -> CRAM -> SAM
+ testv "./test_view -t $ref -S -C $sam > $cram";
+ testv "./test_view -D $cram > $cram.sam_";
+ testv "./compare_sam.pl -nomd $sam $cram.sam_";
+
+ # BAM -> CRAM -> BAM -> SAM
+ $cram = "$bam.cram";
+ testv "./test_view -t $ref -C $bam > $cram";
+ testv "./test_view -b -D $cram > $cram.bam";
+ testv "./test_view $cram.bam > $cram.bam.sam_";
+ testv "./compare_sam.pl -nomd $sam $cram.bam.sam_";
+
+ # SAM -> CRAM3 -> SAM
+ $cram = "$base.tmp.cram";
+ testv "./test_view -t $ref -S -C -o VERSION=3.0 $sam > $cram";
+ testv "./test_view -D $cram > $cram.sam_";
+ testv "./compare_sam.pl -nomd $sam $cram.sam_";
+
+ # BAM -> CRAM3 -> BAM -> SAM
+ $cram = "$bam.cram";
+ testv "./test_view -t $ref -C -o VERSION=3.0 $bam > $cram";
+ testv "./test_view -b -D $cram > $cram.bam";
+ testv "./test_view $cram.bam > $cram.bam.sam_";
+ testv "./compare_sam.pl -nomd $sam $cram.bam.sam_";
+
+ # CRAM3 -> CRAM2
+ $cram = "$base.tmp.cram";
+ testv "./test_view -t $ref -C -o VERSION=2.1 $cram > $cram.cram";
+
+ # CRAM2 -> CRAM3
+ testv "./test_view -t $ref -C -o VERSION=3.0 $cram.cram > $cram";
+ testv "./test_view $cram > $cram.sam_";
+ testv "./compare_sam.pl -nomd $sam $cram.sam_";
+
+ # Java pre-made CRAM -> SAM
+ my $jcram = "${base}_java.cram";
+ if (-e $jcram) {
+ my $jsam = "${base}_java.tmp.sam_";
+ testv "./test_view -i reference=$ref $jcram > $jsam";
+ testv "./compare_sam.pl -nomd $sam $jsam";
+ }
+
+ if ($test_view_failures == 0)
+ {
+ passed($opts, "$sam conversions");
+ }
+ else
+ {
+ failed($opts, "$sam conversions", "$test_view_failures subtests failed");
+ }
+ }
+}
+
+sub test_vcf_api
+{
+ my ($opts,%args) = @_;
+ test_cmd($opts,%args,cmd=>"$$opts{path}/test-vcf-api $$opts{tmp}/test-vcf-api.bcf");
+}
+
+sub test_vcf_sweep
+{
+ my ($opts,%args) = @_;
+ test_cmd($opts,%args,cmd=>"$$opts{path}/test-vcf-sweep $$opts{tmp}/test-vcf-api.bcf");
+}
+
+sub test_vcf_various
+{
+ my ($opts, %args) = @_;
+
+ # Excess spaces in header lines
+ test_cmd($opts, %args, out => "test-vcf-hdr.out",
+ cmd => "$$opts{bin}/htsfile -ch $$opts{path}/test-vcf-hdr-in.vcf");
+
+ # Various VCF parsing issues
+ test_cmd($opts, %args, out => "formatcols.vcf",
+ cmd => "$$opts{bin}/htsfile -c $$opts{path}/formatcols.vcf");
+ test_cmd($opts, %args, out => "noroundtrip-out.vcf",
+ cmd => "$$opts{bin}/htsfile -c $$opts{path}/noroundtrip.vcf");
+}
+
+sub test_convert_padded_header
+{
+ my ($opts, %args) = @_;
+
+ $args{out} = "headernul.tmp.cram";
+ cmd("$$opts{path}/test_view -t ce.fa -C ce#1.sam > $args{out}");
+
+ foreach my $nuls (0, 1, 678) {
+ my $nulsbam = "$$opts{tmp}/headernul$nuls.bam";
+ cmd("$$opts{path}/test_view -b -Z $nuls ce#1.sam > $nulsbam");
+ test_cmd($opts, %args,
+ cmd => "$$opts{path}/test_view -t ce.fa -C $nulsbam");
+ }
+}
--- /dev/null
+/* test/test_view.c -- simple view tool, purely for use in a test harness.
+
+ Copyright (C) 2012 Broad Institute.
+ Copyright (C) 2013-2014 Genome Research Ltd.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <stdio.h>
+#include <unistd.h>
+#include <stdlib.h>
+#include <string.h>
+
+#include "cram/cram.h"
+
+#include "htslib/sam.h"
+
+int main(int argc, char *argv[])
+{
+ samFile *in;
+ char *fn_ref = 0;
+ int flag = 0, c, clevel = -1, ignore_sam_err = 0;
+ char moder[8];
+ bam_hdr_t *h;
+ bam1_t *b;
+ htsFile *out;
+ char modew[800];
+ int r = 0, exit_code = 0;
+ hts_opt *in_opts = NULL, *out_opts = NULL;
+ int nreads = 0;
+ int extra_hdr_nuls = 0;
+ int benchmark = 0;
+
+ while ((c = getopt(argc, argv, "IbDCSl:t:i:o:N:BZ:")) >= 0) {
+ switch (c) {
+ case 'S': flag |= 1; break;
+ case 'b': flag |= 2; break;
+ case 'D': flag |= 4; break;
+ case 'C': flag |= 8; break;
+ case 'B': benchmark = 1; break;
+ case 'l': clevel = atoi(optarg); flag |= 2; break;
+ case 't': fn_ref = optarg; break;
+ case 'I': ignore_sam_err = 1; break;
+ case 'i': if (hts_opt_add(&in_opts, optarg)) return 1; break;
+ case 'o': if (hts_opt_add(&out_opts, optarg)) return 1; break;
+ case 'N': nreads = atoi(optarg); break;
+ case 'Z': extra_hdr_nuls = atoi(optarg); break;
+ }
+ }
+ if (argc == optind) {
+ fprintf(stderr, "Usage: samview [-bSCSIB] [-N num_reads] [-l level] [-o option=value] [-Z hdr_nuls] <in.bam>|<in.sam>|<in.cram> [region]\n");
+ return 1;
+ }
+ strcpy(moder, "r");
+ if (flag&4) strcat(moder, "c");
+ else if ((flag&1) == 0) strcat(moder, "b");
+
+ in = sam_open(argv[optind], moder);
+ if (in == NULL) {
+ fprintf(stderr, "Error opening \"%s\"\n", argv[optind]);
+ return EXIT_FAILURE;
+ }
+ h = sam_hdr_read(in);
+ if (h == NULL) {
+ fprintf(stderr, "Couldn't read header for \"%s\"\n", argv[optind]);
+ return EXIT_FAILURE;
+ }
+ h->ignore_sam_err = ignore_sam_err;
+ if (extra_hdr_nuls) {
+ char *new_text = realloc(h->text, h->l_text + extra_hdr_nuls);
+ if (new_text == NULL) {
+ fprintf(stderr, "Error reallocing header text\n");
+ return EXIT_FAILURE;
+ }
+ h->text = new_text;
+ memset(&h->text[h->l_text], 0, extra_hdr_nuls);
+ h->l_text += extra_hdr_nuls;
+ }
+
+ b = bam_init1();
+
+ strcpy(modew, "w");
+ if (clevel >= 0 && clevel <= 9) sprintf(modew + 1, "%d", clevel);
+ if (flag&8) strcat(modew, "c");
+ else if (flag&2) strcat(modew, "b");
+ out = hts_open("-", modew);
+ if (out == NULL) {
+ fprintf(stderr, "Error opening standard output\n");
+ return EXIT_FAILURE;
+ }
+
+ /* CRAM output */
+ if (flag & 8) {
+ int ret;
+
+ // Parse input header and use for CRAM output
+ out->fp.cram->header = sam_hdr_parse_(h->text, h->l_text);
+
+ // Create CRAM references arrays
+ if (fn_ref)
+ ret = cram_set_option(out->fp.cram, CRAM_OPT_REFERENCE, fn_ref);
+ else
+ // Attempt to fill out a cram->refs[] array from @SQ headers
+ ret = cram_set_option(out->fp.cram, CRAM_OPT_REFERENCE, NULL);
+
+ if (ret != 0)
+ return EXIT_FAILURE;
+ }
+
+ // Process any options; currently cram only.
+ if (hts_opt_apply(in, in_opts))
+ return EXIT_FAILURE;
+ hts_opt_free(in_opts);
+
+ if (hts_opt_apply(out, out_opts))
+ return EXIT_FAILURE;
+ hts_opt_free(out_opts);
+
+ if (!benchmark && sam_hdr_write(out, h) < 0) {
+ fprintf(stderr, "Error writing output header.\n");
+ exit_code = 1;
+ }
+ if (optind + 1 < argc && !(flag&1)) { // BAM input and has a region
+ int i;
+ hts_idx_t *idx;
+ if ((idx = sam_index_load(in, argv[optind])) == 0) {
+ fprintf(stderr, "[E::%s] fail to load the BAM index\n", __func__);
+ return 1;
+ }
+ for (i = optind + 1; i < argc; ++i) {
+ hts_itr_t *iter;
+ if ((iter = sam_itr_querys(idx, h, argv[i])) == 0) {
+ fprintf(stderr, "[E::%s] fail to parse region '%s'\n", __func__, argv[i]);
+ continue;
+ }
+ while ((r = sam_itr_next(in, iter, b)) >= 0) {
+ if (!benchmark && sam_write1(out, h, b) < 0) {
+ fprintf(stderr, "Error writing output.\n");
+ exit_code = 1;
+ break;
+ }
+ if (nreads && --nreads == 0)
+ break;
+ }
+ hts_itr_destroy(iter);
+ }
+ hts_idx_destroy(idx);
+ } else while ((r = sam_read1(in, h, b)) >= 0) {
+ if (!benchmark && sam_write1(out, h, b) < 0) {
+ fprintf(stderr, "Error writing output.\n");
+ exit_code = 1;
+ break;
+ }
+ if (nreads && --nreads == 0)
+ break;
+ }
+
+ if (r < -1) {
+ fprintf(stderr, "Error parsing input.\n");
+ exit_code = 1;
+ }
+
+ r = sam_close(out);
+ if (r < 0) {
+ fprintf(stderr, "Error closing output.\n");
+ exit_code = 1;
+ }
+
+ bam_destroy1(b);
+ bam_hdr_destroy(h);
+
+ r = sam_close(in);
+ if (r < 0) {
+ fprintf(stderr, "Error closing input.\n");
+ exit_code = 1;
+ }
+
+ return exit_code;
+}
--- /dev/null
+@SQ SN:xx LN:20
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--- /dev/null
+@SQ SN:xx LN:20
+a1 0 xx 1 1 1M * 0 0 A # aa:i:1
+a2 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1
+a3 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1 ac:i:1
+a4 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1 ac:i:1 ad:i:1
+a5 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1 ac:i:1 ad:i:1 ae:i:1
+a6 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1 ac:i:1 ad:i:1 ae:i:1 af:i:1
+a7 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1 ac:i:1 ad:i:1 ae:i:1 af:i:1 ag:i:1
+a8 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1 ac:i:1 ad:i:1 ae:i:1 af:i:1 ag:i:1 ah:i:1
+a9 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1 ac:i:1 ad:i:1 ae:i:1 af:i:1 ag:i:1 ah:i:1 ai:i:1
+aA 0 xx 1 1 1M * 0 0 A # aa:i:1 ab:i:1 ac:i:1 ad:i:1 ae:i:1 af:i:1 ag:i:1 ah:i:1 ai:i:1 aj:i:1
--- /dev/null
+@SQ SN:xx LN:20
+@SQ SN:yy LN:20
+a0 16 xx 4 1 10H * 0 0 * *
+a1 16 xx 4 1 5H0M5H * 0 0 * *
+a2 16 xx 4 1 5H0I10M0D5H * 0 0 * *
+A0 16 yy 4 1 0H * 0 0 * *
+A1 16 yy 4 1 0I * 0 0 * *
+A2 16 yy 4 1 0D * 0 0 * *
+A3 16 yy 4 1 0M * 0 0 * *
+A4 16 yy 4 1 0P * 0 0 * *
--- /dev/null
+@SQ SN:xx LN:20
+a1 99 xx 1 1 10M = 11 20 AAAAAAAAAA **********
+b1 99 xx 1 1 10M = 11 20 AAAAAAAAAA **********
+c1 99 xx 1 1 10M = 11 20 AAAAAAAAAA **********
+a1 147 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
+b1 147 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
+c1 147 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
--- /dev/null
+@SQ SN:xx LN:20
+S 67 xx 1 1 10M = 11 20 AAAAAAAAAA **********
+S 131 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
+S 67 xx 1 1 10M = 11 20 AAAAAAAAAA **********
+S 131 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
+S 67 xx 1 1 10M = 11 20 AAAAAAAAAA **********
+S 131 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
--- /dev/null
+@HD VN:1.4 SO:coordinate
+@SQ SN:xx LN:20 AS:? SP:? UR:? M5:bbf4de6d8497a119dda6e074521643dc
+@RG ID:x1 SM:x1
+@RG ID:x2 SM:x2 LB:x PG:foo:bar PI:1111
+@PG ID:emacs PN:emacs VN:23.1.1
+@CO also test
+@CO other headers
+a1 16 xx 1 1 10M * 0 0 AAAAAAAAAA ********** RG:Z:x1
+b1 16 xx 1 1 10M * 0 0 AAAAAAAAAA ********** RG:Z:x2
+c1 16 xx 1 1 10M * 0 0 AAAAAAAAAA **********
+a2 16 xx 11 1 10M * 0 0 TTTTTTTTTT ********** RG:Z:x1
+b2 16 xx 11 1 10M * 0 0 TTTTTTTTTT ********** RG:Z:x2
+c2 16 xx 11 1 10M * 0 0 TTTTTTTTTT **********
--- /dev/null
+@CO xx has been encoded using the SAM spec; leftmost to rightmost
+@CO yy has been encoded using bwa/picard methods; 5' to 3'
+@CO
+@CO 00000000011111111112
+@CO 12345678901234567890
+@CO AAAAAAAAAATTTTTTTTTT
+@CO 1>>>> <<<<2 x1
+@CO
+@CO 1>>>> x2
+@CO <<<<2
+@CO
+@CO 1>>>> x3 (7..15 vs 10..11)
+@CO <<<<2
+@CO
+@CO <<<<2 1>>>> x4 (1..20 vs 16..5)
+@CO
+@SQ SN:xx LN:20
+@SQ SN:yy LN:20
+x1 99 xx 1 1 5M = 16 20 AAAAA *****
+x1 147 xx 16 1 5M = 1 -20 TTTTT *****
+x2 99 xx 7 1 5M = 10 8 AAAAT *****
+x2 147 xx 10 1 5M = 7 -8 ATTTT *****
+x3 147 xx 7 1 5M = 10 8 AAAAT *****
+x3 99 xx 10 1 5M = 7 -8 ATTTT *****
+x4 147 xx 1 1 5M = 16 20 AAAAA *****
+x4 99 xx 16 1 5M = 1 -20 TTTTT *****
+y1 99 yy 1 1 5M = 16 20 AAAAA *****
+y1 147 yy 16 1 5M = 1 -20 TTTTT *****
+y2 99 yy 7 1 5M = 10 8 AAAAT *****
+y2 147 yy 10 1 5M = 7 -8 ATTTT *****
+y3 147 yy 7 1 5M = 10 -2 AAAAT *****
+y3 99 yy 10 1 5M = 7 2 ATTTT *****
+y4 147 yy 1 1 5M = 16 10 AAAAA *****
+y4 99 yy 16 1 5M = 1 -10 TTTTT *****
--- /dev/null
+@CO As per xx#tlen.sam but every read is unsorted with partner
+@CO
+@CO xx has been encoded using the SAM spec; leftmost to rightmost
+@CO yy has been encoded using bwa/picard methods; 5' to 3'
+@CO
+@CO 00000000011111111112
+@CO 12345678901234567890
+@CO AAAAAAAAAATTTTTTTTTT
+@CO 1>>>> <<<<2 x1
+@CO
+@CO 1>>>> x2
+@CO <<<<2
+@CO
+@CO 1>>>> x3 (7..15 vs 10..11)
+@CO <<<<2
+@CO
+@CO <<<<2 1>>>> x4 (1..20 vs 16..5)
+@CO
+@SQ SN:xx LN:20
+@SQ SN:yy LN:20
+x1 147 xx 16 1 5M = 1 -20 TTTTT *****
+x1 99 xx 1 1 5M = 16 20 AAAAA *****
+x2 147 xx 10 1 5M = 7 -8 ATTTT *****
+x2 99 xx 7 1 5M = 10 8 AAAAT *****
+x3 99 xx 10 1 5M = 7 -8 ATTTT *****
+x3 147 xx 7 1 5M = 10 8 AAAAT *****
+x4 99 xx 16 1 5M = 1 -20 TTTTT *****
+x4 147 xx 1 1 5M = 16 20 AAAAA *****
+y1 147 yy 16 1 5M = 1 -20 TTTTT *****
+y1 99 yy 1 1 5M = 16 20 AAAAA *****
+y2 147 yy 10 1 5M = 7 -8 ATTTT *****
+y2 99 yy 7 1 5M = 10 8 AAAAT *****
+y3 99 yy 10 1 5M = 7 2 ATTTT *****
+y3 147 yy 7 1 5M = 10 -2 AAAAT *****
+y4 99 yy 16 1 5M = 1 -10 TTTTT *****
+y4 147 yy 1 1 5M = 16 10 AAAAA *****
--- /dev/null
+@SQ SN:xx LN:20
+@SQ SN:yy LN:20
+a1 67 xx 1 1 10M = 6 20 AAAAAAAAAA **********
+a1 35 xx 6 1 10M = 11 -20 AAAAATTTTT **********
+a1 147 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
+a1 67 yy 1 1 10M = 6 15 AAAAAAAAAA **********
+a1 3 yy 6 1 10M = 1 -15 AAAAATTTTT **********
--- /dev/null
+@SQ SN:xx LN:20
+@SQ SN:yy LN:20
+b1 147 yy 11 1 10M = 1 -20 TTTTTTTTTT **********
+a1 147 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
+a1 99 xx 1 1 10M = 11 20 AAAAAAAAAA **********
+b1 99 yy 1 1 10M = 11 20 AAAAAAAAAA **********
+c1 99 xx 1 1 10M = 11 20 AAAAAAAAAA **********
+c1 147 xx 11 1 10M = 1 -20 TTTTTTTTTT **********
--- /dev/null
+>xx
+AAAAAAAAAATTTTTTTTTT
+>yy
+AAAAAAAAAATTTTTTTTTT
+
--- /dev/null
+xx 20 4 20 21
+yy 20 29 20 21
--- /dev/null
+'\" t
+.TH vcf 5 "August 2013" "htslib" "Bioinformatics formats"
+.SH NAME
+vcf \- Variant Call Format
+.\"
+.\" Copyright (C) 2011 Broad Institute.
+.\" Copyright (C) 2013 Genome Research Ltd.
+.\"
+.\" Author: Heng Li <lh3@sanger.ac.uk>
+.\"
+.\" Permission is hereby granted, free of charge, to any person obtaining a
+.\" copy of this software and associated documentation files (the "Software"),
+.\" to deal in the Software without restriction, including without limitation
+.\" the rights to use, copy, modify, merge, publish, distribute, sublicense,
+.\" and/or sell copies of the Software, and to permit persons to whom the
+.\" Software is furnished to do so, subject to the following conditions:
+.\"
+.\" The above copyright notice and this permission notice shall be included in
+.\" all copies or substantial portions of the Software.
+.\"
+.\" THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+.\" IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+.\" FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+.\" THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+.\" LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+.\" FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+.\" DEALINGS IN THE SOFTWARE.
+.\"
+.SH DESCRIPTION
+The Variant Call Format (VCF) is a TAB-delimited format with each data line
+consisting of the following fields:
+.TS
+nlbl.
+1 CHROM CHROMosome name
+2 POS the left-most POSition of the variant
+3 ID unique variant IDentifier
+4 REF the REFerence allele
+5 ALT the ALTernate allele(s) (comma-separated)
+6 QUAL variant/reference QUALity
+7 FILTER FILTERs applied
+8 INFO INFOrmation related to the variant (semicolon-separated)
+9 FORMAT FORMAT of the genotype fields (optional; colon-separated)
+10+ SAMPLE SAMPLE genotypes and per-sample information (optional)
+.TE
+.P
+The following table gives the \fBINFO\fP tags used by samtools and bcftools.
+.TP
+.B AF1
+Max-likelihood estimate of the site allele frequency (AF) of the first ALT allele
+(double)
+.TP
+.B DP
+Raw read depth (without quality filtering)
+(int)
+.TP
+.B DP4
+# high-quality reference forward bases, ref reverse, alternate for and alt rev bases
+(int[4])
+.TP
+.B FQ
+Consensus quality. Positive: sample genotypes different; negative: otherwise
+(int)
+.TP
+.B MQ
+Root-Mean-Square mapping quality of covering reads
+(int)
+.TP
+.B PC2
+Phred probability of AF in group1 samples being larger (,smaller) than in group2
+(int[2])
+.TP
+.B PCHI2
+Posterior weighted chi^2 P-value between group1 and group2 samples
+(double)
+.TP
+.B PV4
+P-value for strand bias, baseQ bias, mapQ bias and tail distance bias
+(double[4])
+.TP
+.B QCHI2
+Phred-scaled PCHI2
+(int)
+.TP
+.B RP
+# permutations yielding a smaller PCHI2
+(int)
+.TP
+.B CLR
+Phred log ratio of genotype likelihoods with and without the trio/pair constraint
+(int)
+.TP
+.B UGT
+Most probable genotype configuration without the trio constraint
+(string)
+.TP
+.B CGT
+Most probable configuration with the trio constraint
+(string)
+.TP
+.B VDB
+Tests variant positions within reads. Intended for filtering RNA-seq artifacts around splice sites
+(float)
+.TP
+.B RPB
+Mann-Whitney rank-sum test for tail distance bias
+(float)
+.TP
+.B HWE
+Hardy-Weinberg equilibrium test (Wigginton et al)
+(float)
+.P
+.SH SEE ALSO
+.TP
+https://github.com/samtools/hts-specs
+The full VCF/BCF file format specification
+.TP
+.I A note on exact tests of Hardy-Weinberg equilibrium
+Wigginton JE et al
+PMID:15789306
+.\" (http://www.ncbi.nlm.nih.gov/pubmed/15789306)
--- /dev/null
+/* vcf.c -- VCF/BCF API functions.
+
+ Copyright (C) 2012, 2013 Broad Institute.
+ Copyright (C) 2012-2016 Genome Research Ltd.
+ Portions copyright (C) 2014 Intel Corporation.
+
+ Author: Heng Li <lh3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include <zlib.h>
+#include <stdio.h>
+#include <ctype.h>
+#include <assert.h>
+#include <string.h>
+#include <stdlib.h>
+#include <limits.h>
+#include "htslib/kstring.h"
+#include "htslib/bgzf.h"
+#include "htslib/vcf.h"
+#include "htslib/tbx.h"
+#include "htslib/hfile.h"
+#include "htslib/khash_str2int.h"
+#include "hts_internal.h"
+
+#include "htslib/khash.h"
+KHASH_MAP_INIT_STR(vdict, bcf_idinfo_t)
+typedef khash_t(vdict) vdict_t;
+
+#include "htslib/kseq.h"
+KSTREAM_DECLARE(gzFile, gzread)
+
+uint32_t bcf_float_missing = 0x7F800001;
+uint32_t bcf_float_vector_end = 0x7F800002;
+uint8_t bcf_type_shift[] = { 0, 0, 1, 2, 0, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 };
+static bcf_idinfo_t bcf_idinfo_def = { .info = { 15, 15, 15 }, .hrec = { NULL, NULL, NULL}, .id = -1 };
+
+static const char *dump_char(char *buffer, char c)
+{
+ switch (c) {
+ case '\n': strcpy(buffer, "\\n"); break;
+ case '\r': strcpy(buffer, "\\r"); break;
+ case '\t': strcpy(buffer, "\\t"); break;
+ case '\'':
+ case '\"':
+ case '\\':
+ sprintf(buffer, "\\%c", c);
+ break;
+ default:
+ if (isprint_c(c)) sprintf(buffer, "%c", c);
+ else sprintf(buffer, "\\x%02X", (unsigned char) c);
+ break;
+ }
+ return buffer;
+}
+
+/*************************
+ *** VCF header parser ***
+ *************************/
+
+int bcf_hdr_add_sample(bcf_hdr_t *h, const char *s)
+{
+ if ( !s ) return 0;
+
+ const char *ss = s;
+ while ( !*ss && isspace(*ss) ) ss++;
+ if ( !*ss )
+ {
+ fprintf(stderr,"[E::%s] Empty sample name: trailing spaces/tabs in the header line?\n", __func__);
+ abort();
+ }
+
+ vdict_t *d = (vdict_t*)h->dict[BCF_DT_SAMPLE];
+ int ret;
+ char *sdup = strdup(s);
+ int k = kh_put(vdict, d, sdup, &ret);
+ if (ret) { // absent
+ kh_val(d, k) = bcf_idinfo_def;
+ kh_val(d, k).id = kh_size(d) - 1;
+ } else {
+ if (hts_verbose >= 2)
+ {
+ fprintf(stderr, "[E::%s] Duplicated sample name '%s'\n", __func__, s);
+ abort();
+ }
+ free(sdup);
+ return -1;
+ }
+ int n = kh_size(d);
+ h->samples = (char**) realloc(h->samples,sizeof(char*)*n);
+ h->samples[n-1] = sdup;
+ h->dirty = 1;
+ return 0;
+}
+
+int bcf_hdr_parse_sample_line(bcf_hdr_t *h, const char *str)
+{
+ int ret = 0;
+ int i = 0;
+ const char *p, *q;
+ // add samples
+ for (p = q = str;; ++q) {
+ if (*q != '\t' && *q != 0 && *q != '\n') continue;
+ if (++i > 9) {
+ char *s = (char*)malloc(q - p + 1);
+ strncpy(s, p, q - p);
+ s[q - p] = 0;
+ if ( bcf_hdr_add_sample(h,s) < 0 ) ret = -1;
+ free(s);
+ }
+ if (*q == 0 || *q == '\n') break;
+ p = q + 1;
+ }
+ bcf_hdr_add_sample(h,NULL);
+ return ret;
+}
+
+int bcf_hdr_sync(bcf_hdr_t *h)
+{
+ int i;
+ for (i = 0; i < 3; i++)
+ {
+ vdict_t *d = (vdict_t*)h->dict[i];
+ khint_t k;
+ if ( h->n[i] < kh_size(d) )
+ {
+ // this should be true only for i=2, BCF_DT_SAMPLE
+ h->n[i] = kh_size(d);
+ h->id[i] = (bcf_idpair_t*) realloc(h->id[i], kh_size(d)*sizeof(bcf_idpair_t));
+ }
+ for (k=kh_begin(d); k<kh_end(d); k++)
+ {
+ if (!kh_exist(d,k)) continue;
+ h->id[i][kh_val(d,k).id].key = kh_key(d,k);
+ h->id[i][kh_val(d,k).id].val = &kh_val(d,k);
+ }
+ }
+ h->dirty = 0;
+ return 0;
+}
+
+void bcf_hrec_destroy(bcf_hrec_t *hrec)
+{
+ free(hrec->key);
+ if ( hrec->value ) free(hrec->value);
+ int i;
+ for (i=0; i<hrec->nkeys; i++)
+ {
+ free(hrec->keys[i]);
+ free(hrec->vals[i]);
+ }
+ free(hrec->keys);
+ free(hrec->vals);
+ free(hrec);
+}
+
+// Copies all fields except IDX.
+bcf_hrec_t *bcf_hrec_dup(bcf_hrec_t *hrec)
+{
+ bcf_hrec_t *out = (bcf_hrec_t*) calloc(1,sizeof(bcf_hrec_t));
+ out->type = hrec->type;
+ if ( hrec->key ) out->key = strdup(hrec->key);
+ if ( hrec->value ) out->value = strdup(hrec->value);
+ out->nkeys = hrec->nkeys;
+ out->keys = (char**) malloc(sizeof(char*)*hrec->nkeys);
+ out->vals = (char**) malloc(sizeof(char*)*hrec->nkeys);
+ int i, j = 0;
+ for (i=0; i<hrec->nkeys; i++)
+ {
+ if ( hrec->keys[i] && !strcmp("IDX",hrec->keys[i]) ) continue;
+ if ( hrec->keys[i] ) out->keys[j] = strdup(hrec->keys[i]);
+ if ( hrec->vals[i] ) out->vals[j] = strdup(hrec->vals[i]);
+ j++;
+ }
+ if ( i!=j ) out->nkeys -= i-j; // IDX was omitted
+ return out;
+}
+
+void bcf_hrec_debug(FILE *fp, bcf_hrec_t *hrec)
+{
+ fprintf(fp, "key=[%s] value=[%s]", hrec->key, hrec->value?hrec->value:"");
+ int i;
+ for (i=0; i<hrec->nkeys; i++)
+ fprintf(fp, "\t[%s]=[%s]", hrec->keys[i],hrec->vals[i]);
+ fprintf(fp, "\n");
+}
+
+void bcf_header_debug(bcf_hdr_t *hdr)
+{
+ int i, j;
+ for (i=0; i<hdr->nhrec; i++)
+ {
+ if ( !hdr->hrec[i]->value )
+ {
+ fprintf(stderr, "##%s=<", hdr->hrec[i]->key);
+ fprintf(stderr,"%s=%s", hdr->hrec[i]->keys[0], hdr->hrec[i]->vals[0]);
+ for (j=1; j<hdr->hrec[i]->nkeys; j++)
+ fprintf(stderr,",%s=%s", hdr->hrec[i]->keys[j], hdr->hrec[i]->vals[j]);
+ fprintf(stderr,">\n");
+ }
+ else
+ fprintf(stderr,"##%s=%s\n", hdr->hrec[i]->key,hdr->hrec[i]->value);
+ }
+}
+
+void bcf_hrec_add_key(bcf_hrec_t *hrec, const char *str, int len)
+{
+ int n = ++hrec->nkeys;
+ hrec->keys = (char**) realloc(hrec->keys, sizeof(char*)*n);
+ hrec->vals = (char**) realloc(hrec->vals, sizeof(char*)*n);
+ assert( len );
+ hrec->keys[n-1] = (char*) malloc((len+1)*sizeof(char));
+ memcpy(hrec->keys[n-1],str,len);
+ hrec->keys[n-1][len] = 0;
+ hrec->vals[n-1] = NULL;
+}
+
+void bcf_hrec_set_val(bcf_hrec_t *hrec, int i, const char *str, int len, int is_quoted)
+{
+ if ( !str ) { hrec->vals[i] = NULL; return; }
+ if ( hrec->vals[i] ) free(hrec->vals[i]);
+ if ( is_quoted )
+ {
+ hrec->vals[i] = (char*) malloc((len+3)*sizeof(char));
+ hrec->vals[i][0] = '"';
+ memcpy(&hrec->vals[i][1],str,len);
+ hrec->vals[i][len+1] = '"';
+ hrec->vals[i][len+2] = 0;
+ }
+ else
+ {
+ hrec->vals[i] = (char*) malloc((len+1)*sizeof(char));
+ memcpy(hrec->vals[i],str,len);
+ hrec->vals[i][len] = 0;
+ }
+}
+
+void hrec_add_idx(bcf_hrec_t *hrec, int idx)
+{
+ int n = ++hrec->nkeys;
+ hrec->keys = (char**) realloc(hrec->keys, sizeof(char*)*n);
+ hrec->vals = (char**) realloc(hrec->vals, sizeof(char*)*n);
+ hrec->keys[n-1] = strdup("IDX");
+ kstring_t str = {0,0,0};
+ kputw(idx, &str);
+ hrec->vals[n-1] = str.s;
+}
+
+int bcf_hrec_find_key(bcf_hrec_t *hrec, const char *key)
+{
+ int i;
+ for (i=0; i<hrec->nkeys; i++)
+ if ( !strcasecmp(key,hrec->keys[i]) ) return i;
+ return -1;
+}
+
+static inline int is_escaped(const char *min, const char *str)
+{
+ int n = 0;
+ while ( --str>=min && *str=='\\' ) n++;
+ return n%2;
+}
+
+bcf_hrec_t *bcf_hdr_parse_line(const bcf_hdr_t *h, const char *line, int *len)
+{
+ const char *p = line;
+ if (p[0] != '#' || p[1] != '#') { *len = 0; return NULL; }
+ p += 2;
+
+ const char *q = p;
+ while ( *q && *q!='=' ) q++;
+ int n = q-p;
+ if ( *q!='=' || !n ) { *len = q-line+1; return NULL; } // wrong format
+
+ bcf_hrec_t *hrec = (bcf_hrec_t*) calloc(1,sizeof(bcf_hrec_t));
+ hrec->key = (char*) malloc(sizeof(char)*(n+1));
+ memcpy(hrec->key,p,n);
+ hrec->key[n] = 0;
+
+ p = ++q;
+ if ( *p!='<' ) // generic field, e.g. ##samtoolsVersion=0.1.18-r579
+ {
+ while ( *q && *q!='\n' ) q++;
+ hrec->value = (char*) malloc((q-p+1)*sizeof(char));
+ memcpy(hrec->value, p, q-p);
+ hrec->value[q-p] = 0;
+ *len = q-line+1;
+ return hrec;
+ }
+
+ // structured line, e.g.
+ // ##INFO=<ID=PV1,Number=1,Type=Float,Description="P-value for baseQ bias">
+ // ##PEDIGREE=<Name_0=G0-ID,Name_1=G1-ID,Name_3=GN-ID>
+ int nopen = 1;
+ while ( *q && *q!='\n' && nopen>0 )
+ {
+ p = ++q;
+ while ( *q && *q==' ' ) { p++; q++; }
+ // ^[A-Za-z_][0-9A-Za-z_.]*$
+ if (p==q && *q && (isalpha(*q) || *q=='_'))
+ {
+ q++;
+ while ( *q && (isalnum(*q) || *q=='_' || *q=='.') ) q++;
+ }
+ n = q-p;
+ int m = 0;
+ while ( *q && *q==' ' ) { q++; m++; }
+ if ( *q!='=' || !n )
+ {
+ // wrong format
+ while ( *q && *q!='\n' ) q++;
+ kstring_t tmp = {0,0,0};
+ kputsn(line,q-line,&tmp);
+ fprintf(stderr,"Could not parse the header line: \"%s\"\n", tmp.s);
+ free(tmp.s);
+ *len = q-line+1;
+ bcf_hrec_destroy(hrec);
+ return NULL;
+ }
+ bcf_hrec_add_key(hrec, p, q-p-m);
+ p = ++q;
+ while ( *q && *q==' ' ) { p++; q++; }
+ int quoted = *p=='"' ? 1 : 0;
+ if ( quoted ) p++, q++;
+ while ( *q && *q != '\n' )
+ {
+ if ( quoted ) { if ( *q=='"' && !is_escaped(p,q) ) break; }
+ else
+ {
+ if ( *q=='<' ) nopen++;
+ if ( *q=='>' ) nopen--;
+ if ( !nopen ) break;
+ if ( *q==',' && nopen==1 ) break;
+ }
+ q++;
+ }
+ const char *r = q;
+ while ( r > p && r[-1] == ' ' ) r--;
+ bcf_hrec_set_val(hrec, hrec->nkeys-1, p, r-p, quoted);
+ if ( quoted && *q=='"' ) q++;
+ if ( *q=='>' ) { nopen--; q++; }
+ }
+
+ // Skip trailing spaces
+ while ( *q && *q==' ' ) { q++; }
+
+ *len = q-line+1;
+ return hrec;
+}
+
+static int bcf_hdr_set_idx(bcf_hdr_t *hdr, int dict_type, const char *tag, bcf_idinfo_t *idinfo)
+{
+ // If available, preserve existing IDX
+ if ( idinfo->id==-1 )
+ idinfo->id = hdr->n[dict_type]++;
+ else if ( idinfo->id < hdr->n[dict_type] && hdr->id[dict_type][idinfo->id].key )
+ {
+ fprintf(stderr,"[%s:%d %s] Conflicting IDX=%d lines in the header dictionary, the new tag is %s\n", __FILE__,__LINE__,__FUNCTION__, idinfo->id, tag);
+ exit(1);
+ }
+
+ if ( idinfo->id >= hdr->n[dict_type] ) hdr->n[dict_type] = idinfo->id+1;
+ hts_expand0(bcf_idpair_t,hdr->n[dict_type],hdr->m[dict_type],hdr->id[dict_type]);
+
+ // NB: the next kh_put call can invalidate the idinfo pointer, therefore
+ // we leave it unassigned here. It myst be set explicitly in bcf_hdr_sync.
+ hdr->id[dict_type][idinfo->id].key = tag;
+
+ return 0;
+}
+
+// returns: 1 when hdr needs to be synced, 0 otherwise
+int bcf_hdr_register_hrec(bcf_hdr_t *hdr, bcf_hrec_t *hrec)
+{
+ // contig
+ int i,j, ret;
+ khint_t k;
+ char *str;
+ if ( !strcmp(hrec->key, "contig") )
+ {
+ hrec->type = BCF_HL_CTG;
+
+ // Get the contig ID ($str) and length ($j)
+ i = bcf_hrec_find_key(hrec,"length");
+ if ( i<0 ) j = 0;
+ else if ( sscanf(hrec->vals[i],"%d",&j)!=1 ) return 0;
+
+ i = bcf_hrec_find_key(hrec,"ID");
+ if ( i<0 ) return 0;
+ str = strdup(hrec->vals[i]);
+
+ // Register in the dictionary
+ vdict_t *d = (vdict_t*)hdr->dict[BCF_DT_CTG];
+ khint_t k = kh_get(vdict, d, str);
+ if ( k != kh_end(d) ) { free(str); return 0; } // already present
+ k = kh_put(vdict, d, str, &ret);
+
+ int idx = bcf_hrec_find_key(hrec,"IDX");
+ if ( idx!=-1 )
+ {
+ char *tmp = hrec->vals[idx];
+ idx = strtol(hrec->vals[idx], &tmp, 10);
+ if ( *tmp || idx < 0 )
+ {
+ fprintf(stderr,"[%s:%d %s] Error parsing the IDX tag, skipping.\n", __FILE__,__LINE__,__FUNCTION__);
+ return 0;
+ }
+ }
+
+ kh_val(d, k) = bcf_idinfo_def;
+ kh_val(d, k).id = idx;
+ kh_val(d, k).info[0] = j;
+ kh_val(d, k).hrec[0] = hrec;
+ bcf_hdr_set_idx(hdr, BCF_DT_CTG, kh_key(d,k), &kh_val(d,k));
+ if ( idx==-1 ) hrec_add_idx(hrec, kh_val(d,k).id);
+
+ return 1;
+ }
+
+ if ( !strcmp(hrec->key, "INFO") ) hrec->type = BCF_HL_INFO;
+ else if ( !strcmp(hrec->key, "FILTER") ) hrec->type = BCF_HL_FLT;
+ else if ( !strcmp(hrec->key, "FORMAT") ) hrec->type = BCF_HL_FMT;
+ else if ( hrec->nkeys>0 ) { hrec->type = BCF_HL_STR; return 1; }
+ else return 0;
+
+ // INFO/FILTER/FORMAT
+ char *id = NULL;
+ int type = -1, num = -1, var = -1, idx = -1;
+ for (i=0; i<hrec->nkeys; i++)
+ {
+ if ( !strcmp(hrec->keys[i], "ID") ) id = hrec->vals[i];
+ else if ( !strcmp(hrec->keys[i], "IDX") )
+ {
+ char *tmp = hrec->vals[i];
+ idx = strtol(hrec->vals[i], &tmp, 10);
+ if ( *tmp || idx < 0 )
+ {
+ fprintf(stderr,"[%s:%d %s] Error parsing the IDX tag, skipping.\n", __FILE__,__LINE__,__FUNCTION__);
+ return 0;
+ }
+ }
+ else if ( !strcmp(hrec->keys[i], "Type") )
+ {
+ if ( !strcmp(hrec->vals[i], "Integer") ) type = BCF_HT_INT;
+ else if ( !strcmp(hrec->vals[i], "Float") ) type = BCF_HT_REAL;
+ else if ( !strcmp(hrec->vals[i], "String") ) type = BCF_HT_STR;
+ else if ( !strcmp(hrec->vals[i], "Character") ) type = BCF_HT_STR;
+ else if ( !strcmp(hrec->vals[i], "Flag") ) type = BCF_HT_FLAG;
+ else
+ {
+ if (hts_verbose >= 2) fprintf(stderr, "[E::%s] The type \"%s\" is not supported, assuming \"String\"\n", __func__, hrec->vals[i]);
+ type = BCF_HT_STR;
+ }
+ }
+ else if ( !strcmp(hrec->keys[i], "Number") )
+ {
+ if ( !strcmp(hrec->vals[i],"A") ) var = BCF_VL_A;
+ else if ( !strcmp(hrec->vals[i],"R") ) var = BCF_VL_R;
+ else if ( !strcmp(hrec->vals[i],"G") ) var = BCF_VL_G;
+ else if ( !strcmp(hrec->vals[i],".") ) var = BCF_VL_VAR;
+ else
+ {
+ sscanf(hrec->vals[i],"%d",&num);
+ var = BCF_VL_FIXED;
+ }
+ if (var != BCF_VL_FIXED) num = 0xfffff;
+ }
+ }
+ uint32_t info = (uint32_t)num<<12 | var<<8 | type<<4 | hrec->type;
+
+ if ( !id ) return 0;
+ str = strdup(id);
+
+ vdict_t *d = (vdict_t*)hdr->dict[BCF_DT_ID];
+ k = kh_get(vdict, d, str);
+ if ( k != kh_end(d) )
+ {
+ // already present
+ free(str);
+ if ( kh_val(d, k).hrec[info&0xf] ) return 0;
+ kh_val(d, k).info[info&0xf] = info;
+ kh_val(d, k).hrec[info&0xf] = hrec;
+ if ( idx==-1 ) hrec_add_idx(hrec, kh_val(d, k).id);
+ return 1;
+ }
+ k = kh_put(vdict, d, str, &ret);
+ kh_val(d, k) = bcf_idinfo_def;
+ kh_val(d, k).info[info&0xf] = info;
+ kh_val(d, k).hrec[info&0xf] = hrec;
+ kh_val(d, k).id = idx;
+ bcf_hdr_set_idx(hdr, BCF_DT_ID, kh_key(d,k), &kh_val(d,k));
+ if ( idx==-1 ) hrec_add_idx(hrec, kh_val(d,k).id);
+
+ return 1;
+}
+
+int bcf_hdr_add_hrec(bcf_hdr_t *hdr, bcf_hrec_t *hrec)
+{
+ if ( !hrec ) return 0;
+
+ hrec->type = BCF_HL_GEN;
+ if ( !bcf_hdr_register_hrec(hdr,hrec) )
+ {
+ // If one of the hashed field, then it is already present
+ if ( hrec->type != BCF_HL_GEN )
+ {
+ bcf_hrec_destroy(hrec);
+ return 0;
+ }
+
+ // Is one of the generic fields and already present?
+ int i;
+ for (i=0; i<hdr->nhrec; i++)
+ {
+ if ( hdr->hrec[i]->type!=BCF_HL_GEN ) continue;
+ if ( !strcmp(hdr->hrec[i]->key,hrec->key) && !strcmp(hrec->key,"fileformat") ) break;
+ if ( !strcmp(hdr->hrec[i]->key,hrec->key) && !strcmp(hdr->hrec[i]->value,hrec->value) ) break;
+ }
+ if ( i<hdr->nhrec )
+ {
+ bcf_hrec_destroy(hrec);
+ return 0;
+ }
+ }
+
+ // New record, needs to be added
+ int n = ++hdr->nhrec;
+ hdr->hrec = (bcf_hrec_t**) realloc(hdr->hrec, n*sizeof(bcf_hrec_t*));
+ hdr->hrec[n-1] = hrec;
+ hdr->dirty = 1;
+
+ return hrec->type==BCF_HL_GEN ? 0 : 1;
+}
+
+/*
+ * Note that while querying of FLT,INFO,FMT,CTG lines is fast (the keys are hashed),
+ * the STR,GEN lines are searched for linearly in a linked list of all header lines.
+ * This may become a problem for VCFs with huge headers, we might need to build a
+ * dictionary for these lines as well.
+ */
+bcf_hrec_t *bcf_hdr_get_hrec(const bcf_hdr_t *hdr, int type, const char *key, const char *value, const char *str_class)
+{
+ int i;
+ if ( type==BCF_HL_GEN )
+ {
+ for (i=0; i<hdr->nhrec; i++)
+ {
+ if ( hdr->hrec[i]->type!=type ) continue;
+ if ( strcmp(hdr->hrec[i]->key,key) ) continue;
+ if ( !value || !strcmp(hdr->hrec[i]->value,value) ) return hdr->hrec[i];
+ }
+ return NULL;
+ }
+ else if ( type==BCF_HL_STR )
+ {
+ for (i=0; i<hdr->nhrec; i++)
+ {
+ if ( hdr->hrec[i]->type!=type ) continue;
+ if ( strcmp(hdr->hrec[i]->key,str_class) ) continue;
+ int j = bcf_hrec_find_key(hdr->hrec[i],key);
+ if ( j>=0 && !strcmp(hdr->hrec[i]->vals[j],value) ) return hdr->hrec[i];
+ }
+ return NULL;
+ }
+ vdict_t *d = type==BCF_HL_CTG ? (vdict_t*)hdr->dict[BCF_DT_CTG] : (vdict_t*)hdr->dict[BCF_DT_ID];
+ khint_t k = kh_get(vdict, d, value);
+ if ( k == kh_end(d) ) return NULL;
+ return kh_val(d, k).hrec[type==BCF_HL_CTG?0:type];
+}
+
+void bcf_hdr_check_sanity(bcf_hdr_t *hdr)
+{
+ static int PL_warned = 0, GL_warned = 0;
+
+ if ( !PL_warned )
+ {
+ int id = bcf_hdr_id2int(hdr, BCF_DT_ID, "PL");
+ if ( bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,id) && bcf_hdr_id2length(hdr,BCF_HL_FMT,id)!=BCF_VL_G )
+ {
+ if (hts_verbose >= 2) fprintf(stderr,"[W::%s] PL should be declared as Number=G\n", __func__);
+ PL_warned = 1;
+ }
+ }
+ if ( !GL_warned )
+ {
+ int id = bcf_hdr_id2int(hdr, BCF_DT_ID, "GL");
+ if ( bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,id) && bcf_hdr_id2length(hdr,BCF_HL_FMT,id)!=BCF_VL_G )
+ {
+ if (hts_verbose >= 2) fprintf(stderr,"[W::%s] GL should be declared as Number=G\n", __func__);
+ GL_warned = 1;
+ }
+ }
+}
+
+int bcf_hdr_parse(bcf_hdr_t *hdr, char *htxt)
+{
+ int len, needs_sync = 0;
+ char *p = htxt;
+
+ // Check sanity: "fileformat" string must come as first
+ bcf_hrec_t *hrec = bcf_hdr_parse_line(hdr,p,&len);
+ if ( !hrec || !hrec->key || strcasecmp(hrec->key,"fileformat") )
+ fprintf(stderr, "[W::%s] The first line should be ##fileformat; is the VCF/BCF header broken?\n", __func__);
+ needs_sync += bcf_hdr_add_hrec(hdr, hrec);
+
+ // The filter PASS must appear first in the dictionary
+ hrec = bcf_hdr_parse_line(hdr,"##FILTER=<ID=PASS,Description=\"All filters passed\">",&len);
+ needs_sync += bcf_hdr_add_hrec(hdr, hrec);
+
+ // Parse the whole header
+ while ( (hrec=bcf_hdr_parse_line(hdr,p,&len)) )
+ {
+ needs_sync += bcf_hdr_add_hrec(hdr, hrec);
+ p += len;
+ }
+ int ret = bcf_hdr_parse_sample_line(hdr,p);
+ bcf_hdr_sync(hdr);
+ bcf_hdr_check_sanity(hdr);
+ return ret;
+}
+
+int bcf_hdr_append(bcf_hdr_t *hdr, const char *line)
+{
+ int len;
+ bcf_hrec_t *hrec = bcf_hdr_parse_line(hdr, (char*) line, &len);
+ if ( !hrec ) return -1;
+ bcf_hdr_add_hrec(hdr, hrec);
+ return 0;
+}
+
+void bcf_hdr_remove(bcf_hdr_t *hdr, int type, const char *key)
+{
+ int i = 0;
+ bcf_hrec_t *hrec;
+ if ( !key )
+ {
+ while ( i<hdr->nhrec )
+ {
+ if ( hdr->hrec[i]->type!=type ) { i++; continue; }
+ hrec = hdr->hrec[i];
+
+ if ( type==BCF_HL_FLT || type==BCF_HL_INFO || type==BCF_HL_FMT || type== BCF_HL_CTG )
+ {
+ int j = bcf_hrec_find_key(hdr->hrec[i], "ID");
+ if ( j>0 )
+ {
+ vdict_t *d = type==BCF_HL_CTG ? (vdict_t*)hdr->dict[BCF_DT_CTG] : (vdict_t*)hdr->dict[BCF_DT_ID];
+ khint_t k = kh_get(vdict, d, hdr->hrec[i]->vals[j]);
+ kh_val(d, k).hrec[type==BCF_HL_CTG?0:type] = NULL;
+ }
+ }
+
+ hdr->dirty = 1;
+ hdr->nhrec--;
+ if ( i < hdr->nhrec )
+ memmove(&hdr->hrec[i],&hdr->hrec[i+1],(hdr->nhrec-i)*sizeof(bcf_hrec_t*));
+ bcf_hrec_destroy(hrec);
+ }
+ return;
+ }
+ while (1)
+ {
+ if ( type==BCF_HL_FLT || type==BCF_HL_INFO || type==BCF_HL_FMT || type== BCF_HL_CTG )
+ {
+ hrec = bcf_hdr_get_hrec(hdr, type, "ID", key, NULL);
+ if ( !hrec ) return;
+
+ for (i=0; i<hdr->nhrec; i++)
+ if ( hdr->hrec[i]==hrec ) break;
+ assert( i<hdr->nhrec );
+
+ vdict_t *d = type==BCF_HL_CTG ? (vdict_t*)hdr->dict[BCF_DT_CTG] : (vdict_t*)hdr->dict[BCF_DT_ID];
+ khint_t k = kh_get(vdict, d, key);
+ kh_val(d, k).hrec[type==BCF_HL_CTG?0:type] = NULL;
+ }
+ else
+ {
+ for (i=0; i<hdr->nhrec; i++)
+ {
+ if ( hdr->hrec[i]->type!=type ) continue;
+ if ( type==BCF_HL_GEN )
+ {
+ if ( !strcmp(hdr->hrec[i]->key,key) ) break;
+ }
+ else
+ {
+ // not all structured lines have ID, we could be more sophisticated as in bcf_hdr_get_hrec()
+ int j = bcf_hrec_find_key(hdr->hrec[i], "ID");
+ if ( j>=0 && !strcmp(hdr->hrec[i]->vals[j],key) ) break;
+ }
+ }
+ if ( i==hdr->nhrec ) return;
+ hrec = hdr->hrec[i];
+ }
+
+ hdr->nhrec--;
+ if ( i < hdr->nhrec )
+ memmove(&hdr->hrec[i],&hdr->hrec[i+1],(hdr->nhrec-i)*sizeof(bcf_hrec_t*));
+ bcf_hrec_destroy(hrec);
+ hdr->dirty = 1;
+ }
+}
+
+int bcf_hdr_printf(bcf_hdr_t *hdr, const char *fmt, ...)
+{
+ va_list ap;
+ va_start(ap, fmt);
+ int n = vsnprintf(NULL, 0, fmt, ap) + 2;
+ va_end(ap);
+
+ char *line = (char*)malloc(n);
+ va_start(ap, fmt);
+ vsnprintf(line, n, fmt, ap);
+ va_end(ap);
+
+ int ret = bcf_hdr_append(hdr, line);
+
+ free(line);
+ return ret;
+}
+
+
+/**********************
+ *** BCF header I/O ***
+ **********************/
+
+const char *bcf_hdr_get_version(const bcf_hdr_t *hdr)
+{
+ bcf_hrec_t *hrec = bcf_hdr_get_hrec(hdr, BCF_HL_GEN, "fileformat", NULL, NULL);
+ if ( !hrec )
+ {
+ fprintf(stderr,"No version string found, assuming VCFv4.2\n");
+ return "VCFv4.2";
+ }
+ return hrec->value;
+}
+
+void bcf_hdr_set_version(bcf_hdr_t *hdr, const char *version)
+{
+ bcf_hrec_t *hrec = bcf_hdr_get_hrec(hdr, BCF_HL_GEN, "fileformat", NULL, NULL);
+ if ( !hrec )
+ {
+ int len;
+ kstring_t str = {0,0,0};
+ ksprintf(&str,"##fileformat=%s", version);
+ hrec = bcf_hdr_parse_line(hdr, str.s, &len);
+ free(str.s);
+ }
+ else
+ {
+ free(hrec->value);
+ hrec->value = strdup(version);
+ }
+ hdr->dirty = 1;
+}
+
+bcf_hdr_t *bcf_hdr_init(const char *mode)
+{
+ int i;
+ bcf_hdr_t *h;
+ h = (bcf_hdr_t*)calloc(1, sizeof(bcf_hdr_t));
+ if (!h) return NULL;
+ for (i = 0; i < 3; ++i)
+ if ((h->dict[i] = kh_init(vdict)) == NULL) goto fail;
+ if ( strchr(mode,'w') )
+ {
+ bcf_hdr_append(h, "##fileformat=VCFv4.2");
+ // The filter PASS must appear first in the dictionary
+ bcf_hdr_append(h, "##FILTER=<ID=PASS,Description=\"All filters passed\">");
+ }
+ return h;
+
+ fail:
+ for (i = 0; i < 3; ++i)
+ kh_destroy(vdict, h->dict[i]);
+ free(h);
+ return NULL;
+}
+
+void bcf_hdr_destroy(bcf_hdr_t *h)
+{
+ int i;
+ khint_t k;
+ for (i = 0; i < 3; ++i) {
+ vdict_t *d = (vdict_t*)h->dict[i];
+ if (d == 0) continue;
+ for (k = kh_begin(d); k != kh_end(d); ++k)
+ if (kh_exist(d, k)) free((char*)kh_key(d, k));
+ kh_destroy(vdict, d);
+ free(h->id[i]);
+ }
+ for (i=0; i<h->nhrec; i++)
+ bcf_hrec_destroy(h->hrec[i]);
+ if (h->nhrec) free(h->hrec);
+ if (h->samples) free(h->samples);
+ free(h->keep_samples);
+ free(h->transl[0]); free(h->transl[1]);
+ free(h->mem.s);
+ free(h);
+}
+
+bcf_hdr_t *bcf_hdr_read(htsFile *hfp)
+{
+ if (hfp->format.format == vcf)
+ return vcf_hdr_read(hfp);
+
+ BGZF *fp = hfp->fp.bgzf;
+ uint8_t magic[5];
+ bcf_hdr_t *h;
+ h = bcf_hdr_init("r");
+ if (!h) {
+ fprintf(stderr, "[E::%s] failed to allocate bcf header\n", __func__);
+ return NULL;
+ }
+ if (bgzf_read(fp, magic, 5) != 5)
+ {
+ fprintf(stderr,"[%s:%d %s] Failed to read the header (reading BCF in text mode?)\n", __FILE__,__LINE__,__FUNCTION__);
+ bcf_hdr_destroy(h);
+ return NULL;
+ }
+ if (strncmp((char*)magic, "BCF\2\2", 5) != 0)
+ {
+ if (!strncmp((char*)magic, "BCF", 3))
+ fprintf(stderr,"[%s:%d %s] invalid BCF2 magic string: only BCFv2.2 is supported.\n", __FILE__,__LINE__,__FUNCTION__);
+ else if (hts_verbose >= 2)
+ fprintf(stderr, "[E::%s] invalid BCF2 magic string\n", __func__);
+ bcf_hdr_destroy(h);
+ return NULL;
+ }
+ int hlen;
+ char *htxt = NULL;
+ if (bgzf_read(fp, &hlen, 4) != 4) goto fail;
+ htxt = (char*)malloc(hlen);
+ if (!htxt) goto fail;
+ if (bgzf_read(fp, htxt, hlen) != hlen) goto fail;
+ bcf_hdr_parse(h, htxt); // FIXME: Does this return anything meaningful?
+ free(htxt);
+ return h;
+ fail:
+ if (hts_verbose >= 2) {
+ fprintf(stderr, "[E::%s] failed to read BCF header\n", __func__);
+ }
+ free(htxt);
+ bcf_hdr_destroy(h);
+ return NULL;
+}
+
+int bcf_hdr_write(htsFile *hfp, bcf_hdr_t *h)
+{
+ if ( h->dirty ) bcf_hdr_sync(h);
+ if (hfp->format.format == vcf || hfp->format.format == text_format)
+ return vcf_hdr_write(hfp, h);
+
+ int hlen;
+ char *htxt = bcf_hdr_fmt_text(h, 1, &hlen);
+ hlen++; // include the \0 byte
+
+ BGZF *fp = hfp->fp.bgzf;
+ if ( bgzf_write(fp, "BCF\2\2", 5) !=5 ) return -1;
+ if ( bgzf_write(fp, &hlen, 4) !=4 ) return -1;
+ if ( bgzf_write(fp, htxt, hlen) != hlen ) return -1;
+
+ free(htxt);
+ return 0;
+}
+
+/********************
+ *** BCF site I/O ***
+ ********************/
+
+bcf1_t *bcf_init()
+{
+ bcf1_t *v;
+ v = (bcf1_t*)calloc(1, sizeof(bcf1_t));
+ return v;
+}
+
+void bcf_clear(bcf1_t *v)
+{
+ int i;
+ for (i=0; i<v->d.m_info; i++)
+ {
+ if ( v->d.info[i].vptr_free )
+ {
+ free(v->d.info[i].vptr - v->d.info[i].vptr_off);
+ v->d.info[i].vptr_free = 0;
+ }
+ }
+ for (i=0; i<v->d.m_fmt; i++)
+ {
+ if ( v->d.fmt[i].p_free )
+ {
+ free(v->d.fmt[i].p - v->d.fmt[i].p_off);
+ v->d.fmt[i].p_free = 0;
+ }
+ }
+ v->rid = v->pos = v->rlen = v->unpacked = 0;
+ bcf_float_set_missing(v->qual);
+ v->n_info = v->n_allele = v->n_fmt = v->n_sample = 0;
+ v->shared.l = v->indiv.l = 0;
+ v->d.var_type = -1;
+ v->d.shared_dirty = 0;
+ v->d.indiv_dirty = 0;
+ v->d.n_flt = 0;
+ v->errcode = 0;
+ if (v->d.m_als) v->d.als[0] = 0;
+ if (v->d.m_id) v->d.id[0] = 0;
+}
+
+void bcf_empty(bcf1_t *v)
+{
+ bcf_clear1(v);
+ free(v->d.id);
+ free(v->d.als);
+ free(v->d.allele); free(v->d.flt); free(v->d.info); free(v->d.fmt);
+ if (v->d.var ) free(v->d.var);
+ free(v->shared.s); free(v->indiv.s);
+}
+
+void bcf_destroy(bcf1_t *v)
+{
+ bcf_empty1(v);
+ free(v);
+}
+
+static inline int bcf_read1_core(BGZF *fp, bcf1_t *v)
+{
+ uint32_t x[8];
+ int ret;
+ if ((ret = bgzf_read(fp, x, 32)) != 32) {
+ if (ret == 0) return -1;
+ return -2;
+ }
+ bcf_clear1(v);
+ x[0] -= 24; // to exclude six 32-bit integers
+ ks_resize(&v->shared, x[0]);
+ ks_resize(&v->indiv, x[1]);
+ memcpy(v, x + 2, 16);
+ v->n_allele = x[6]>>16; v->n_info = x[6]&0xffff;
+ v->n_fmt = x[7]>>24; v->n_sample = x[7]&0xffffff;
+ v->shared.l = x[0], v->indiv.l = x[1];
+ // silent fix of broken BCFs produced by earlier versions of bcf_subset, prior to and including bd6ed8b4
+ if ( (!v->indiv.l || !v->n_sample) && v->n_fmt ) v->n_fmt = 0;
+
+ if (bgzf_read(fp, v->shared.s, v->shared.l) != v->shared.l) return -1;
+ if (bgzf_read(fp, v->indiv.s, v->indiv.l) != v->indiv.l) return -1;
+ return 0;
+}
+
+#define bit_array_size(n) ((n)/8+1)
+#define bit_array_set(a,i) ((a)[(i)/8] |= 1 << ((i)%8))
+#define bit_array_clear(a,i) ((a)[(i)/8] &= ~(1 << ((i)%8)))
+#define bit_array_test(a,i) ((a)[(i)/8] & (1 << ((i)%8)))
+
+static inline uint8_t *bcf_unpack_fmt_core1(uint8_t *ptr, int n_sample, bcf_fmt_t *fmt);
+int bcf_subset_format(const bcf_hdr_t *hdr, bcf1_t *rec)
+{
+ if ( !hdr->keep_samples ) return 0;
+ if ( !bcf_hdr_nsamples(hdr) )
+ {
+ rec->indiv.l = rec->n_sample = 0;
+ return 0;
+ }
+
+ int i, j;
+ uint8_t *ptr = (uint8_t*)rec->indiv.s, *dst = NULL, *src;
+ bcf_dec_t *dec = &rec->d;
+ hts_expand(bcf_fmt_t, rec->n_fmt, dec->m_fmt, dec->fmt);
+ for (i=0; i<dec->m_fmt; ++i) dec->fmt[i].p_free = 0;
+
+ for (i=0; i<rec->n_fmt; i++)
+ {
+ ptr = bcf_unpack_fmt_core1(ptr, rec->n_sample, &dec->fmt[i]);
+ src = dec->fmt[i].p - dec->fmt[i].size;
+ if ( dst )
+ {
+ memmove(dec->fmt[i-1].p + dec->fmt[i-1].p_len, dec->fmt[i].p - dec->fmt[i].p_off, dec->fmt[i].p_off);
+ dec->fmt[i].p = dec->fmt[i-1].p + dec->fmt[i-1].p_len + dec->fmt[i].p_off;
+ }
+ dst = dec->fmt[i].p;
+ for (j=0; j<hdr->nsamples_ori; j++)
+ {
+ src += dec->fmt[i].size;
+ if ( !bit_array_test(hdr->keep_samples,j) ) continue;
+ memmove(dst, src, dec->fmt[i].size);
+ dst += dec->fmt[i].size;
+ }
+ rec->indiv.l -= dec->fmt[i].p_len - (dst - dec->fmt[i].p);
+ dec->fmt[i].p_len = dst - dec->fmt[i].p;
+ }
+ rec->unpacked |= BCF_UN_FMT;
+
+ rec->n_sample = bcf_hdr_nsamples(hdr);
+ return 0;
+}
+
+int bcf_read(htsFile *fp, const bcf_hdr_t *h, bcf1_t *v)
+{
+ if (fp->format.format == vcf) return vcf_read(fp,h,v);
+ int ret = bcf_read1_core(fp->fp.bgzf, v);
+ if ( ret!=0 || !h->keep_samples ) return ret;
+ return bcf_subset_format(h,v);
+}
+
+int bcf_readrec(BGZF *fp, void *null, void *vv, int *tid, int *beg, int *end)
+{
+ bcf1_t *v = (bcf1_t *) vv;
+ int ret;
+ if ((ret = bcf_read1_core(fp, v)) >= 0)
+ *tid = v->rid, *beg = v->pos, *end = v->pos + v->rlen;
+ return ret;
+}
+
+static inline void bcf1_sync_id(bcf1_t *line, kstring_t *str)
+{
+ // single typed string
+ if ( line->d.id && strcmp(line->d.id, ".") ) bcf_enc_vchar(str, strlen(line->d.id), line->d.id);
+ else bcf_enc_size(str, 0, BCF_BT_CHAR);
+}
+static inline void bcf1_sync_alleles(bcf1_t *line, kstring_t *str)
+{
+ // list of typed strings
+ int i;
+ for (i=0; i<line->n_allele; i++)
+ bcf_enc_vchar(str, strlen(line->d.allele[i]), line->d.allele[i]);
+ if ( !line->rlen && line->n_allele ) line->rlen = strlen(line->d.allele[0]);
+}
+static inline void bcf1_sync_filter(bcf1_t *line, kstring_t *str)
+{
+ // typed vector of integers
+ if ( line->d.n_flt ) bcf_enc_vint(str, line->d.n_flt, line->d.flt, -1);
+ else bcf_enc_vint(str, 0, 0, -1);
+}
+
+static inline void bcf1_sync_info(bcf1_t *line, kstring_t *str)
+{
+ // pairs of typed vectors
+ int i, irm = -1;
+ for (i=0; i<line->n_info; i++)
+ {
+ bcf_info_t *info = &line->d.info[i];
+ if ( !info->vptr )
+ {
+ // marked for removal
+ if ( irm < 0 ) irm = i;
+ continue;
+ }
+ kputsn_(info->vptr - info->vptr_off, info->vptr_len + info->vptr_off, str);
+ if ( irm >=0 )
+ {
+ bcf_info_t tmp = line->d.info[irm]; line->d.info[irm] = line->d.info[i]; line->d.info[i] = tmp;
+ while ( irm<=i && line->d.info[irm].vptr ) irm++;
+ }
+ }
+ if ( irm>=0 ) line->n_info = irm;
+}
+
+static int bcf1_sync(bcf1_t *line)
+{
+ char *shared_ori = line->shared.s;
+ size_t prev_len;
+
+ kstring_t tmp = {0,0,0};
+ if ( !line->shared.l )
+ {
+ // New line created via API, BCF data blocks do not exist. Get it ready for BCF output
+ tmp = line->shared;
+ bcf1_sync_id(line, &tmp);
+ line->unpack_size[0] = tmp.l; prev_len = tmp.l;
+
+ bcf1_sync_alleles(line, &tmp);
+ line->unpack_size[1] = tmp.l - prev_len; prev_len = tmp.l;
+
+ bcf1_sync_filter(line, &tmp);
+ line->unpack_size[2] = tmp.l - prev_len;
+
+ bcf1_sync_info(line, &tmp);
+ line->shared = tmp;
+ }
+ else if ( line->d.shared_dirty )
+ {
+ // The line was edited, update the BCF data block.
+
+ if ( !(line->unpacked & BCF_UN_STR) ) bcf_unpack(line,BCF_UN_STR);
+
+ // ptr_ori points to the original unchanged BCF data.
+ uint8_t *ptr_ori = (uint8_t *) line->shared.s;
+
+ // ID: single typed string
+ if ( line->d.shared_dirty & BCF1_DIRTY_ID )
+ bcf1_sync_id(line, &tmp);
+ else
+ kputsn_(ptr_ori, line->unpack_size[0], &tmp);
+ ptr_ori += line->unpack_size[0];
+ line->unpack_size[0] = tmp.l; prev_len = tmp.l;
+
+ // REF+ALT: list of typed strings
+ if ( line->d.shared_dirty & BCF1_DIRTY_ALS )
+ bcf1_sync_alleles(line, &tmp);
+ else
+ {
+ kputsn_(ptr_ori, line->unpack_size[1], &tmp);
+ if ( !line->rlen && line->n_allele ) line->rlen = strlen(line->d.allele[0]);
+ }
+ ptr_ori += line->unpack_size[1];
+ line->unpack_size[1] = tmp.l - prev_len; prev_len = tmp.l;
+
+ if ( line->unpacked & BCF_UN_FLT )
+ {
+ // FILTER: typed vector of integers
+ if ( line->d.shared_dirty & BCF1_DIRTY_FLT )
+ bcf1_sync_filter(line, &tmp);
+ else if ( line->d.n_flt )
+ kputsn_(ptr_ori, line->unpack_size[2], &tmp);
+ else
+ bcf_enc_vint(&tmp, 0, 0, -1);
+ ptr_ori += line->unpack_size[2];
+ line->unpack_size[2] = tmp.l - prev_len;
+
+ if ( line->unpacked & BCF_UN_INFO )
+ {
+ // INFO: pairs of typed vectors
+ if ( line->d.shared_dirty & BCF1_DIRTY_INF )
+ {
+ bcf1_sync_info(line, &tmp);
+ ptr_ori = (uint8_t*)line->shared.s + line->shared.l;
+ }
+ }
+ }
+
+ int size = line->shared.l - (size_t)ptr_ori + (size_t)line->shared.s;
+ if ( size ) kputsn_(ptr_ori, size, &tmp);
+
+ free(line->shared.s);
+ line->shared = tmp;
+ }
+ if ( line->shared.s != shared_ori && line->unpacked & BCF_UN_INFO )
+ {
+ // Reallocated line->shared.s block invalidated line->d.info[].vptr pointers
+ size_t off_new = line->unpack_size[0] + line->unpack_size[1] + line->unpack_size[2];
+ int i;
+ for (i=0; i<line->n_info; i++)
+ {
+ uint8_t *vptr_free = line->d.info[i].vptr_free ? line->d.info[i].vptr - line->d.info[i].vptr_off : NULL;
+ line->d.info[i].vptr = (uint8_t*) line->shared.s + off_new + line->d.info[i].vptr_off;
+ off_new += line->d.info[i].vptr_len + line->d.info[i].vptr_off;
+ if ( vptr_free )
+ {
+ free(vptr_free);
+ line->d.info[i].vptr_free = 0;
+ }
+ }
+ }
+
+ if ( line->n_sample && line->n_fmt && (!line->indiv.l || line->d.indiv_dirty) )
+ {
+ // The genotype fields changed or are not present
+ tmp.l = tmp.m = 0; tmp.s = NULL;
+ int i, irm = -1;
+ for (i=0; i<line->n_fmt; i++)
+ {
+ bcf_fmt_t *fmt = &line->d.fmt[i];
+ if ( !fmt->p )
+ {
+ // marked for removal
+ if ( irm < 0 ) irm = i;
+ continue;
+ }
+ kputsn_(fmt->p - fmt->p_off, fmt->p_len + fmt->p_off, &tmp);
+ if ( irm >=0 )
+ {
+ bcf_fmt_t tfmt = line->d.fmt[irm]; line->d.fmt[irm] = line->d.fmt[i]; line->d.fmt[i] = tfmt;
+ while ( irm<=i && line->d.fmt[irm].p ) irm++;
+ }
+
+ }
+ if ( irm>=0 ) line->n_fmt = irm;
+ free(line->indiv.s);
+ line->indiv = tmp;
+
+ // Reallocated line->indiv.s block invalidated line->d.fmt[].p pointers
+ size_t off_new = 0;
+ for (i=0; i<line->n_fmt; i++)
+ {
+ uint8_t *p_free = line->d.fmt[i].p_free ? line->d.fmt[i].p - line->d.fmt[i].p_off : NULL;
+ line->d.fmt[i].p = (uint8_t*) line->indiv.s + off_new + line->d.fmt[i].p_off;
+ off_new += line->d.fmt[i].p_len + line->d.fmt[i].p_off;
+ if ( p_free )
+ {
+ free(p_free);
+ line->d.fmt[i].p_free = 0;
+ }
+ }
+ }
+ if ( !line->n_sample ) line->n_fmt = 0;
+ line->d.shared_dirty = line->d.indiv_dirty = 0;
+ return 0;
+}
+
+bcf1_t *bcf_copy(bcf1_t *dst, bcf1_t *src)
+{
+ bcf1_sync(src);
+
+ bcf_clear(dst);
+ dst->rid = src->rid;
+ dst->pos = src->pos;
+ dst->rlen = src->rlen;
+ dst->qual = src->qual;
+ dst->n_info = src->n_info; dst->n_allele = src->n_allele;
+ dst->n_fmt = src->n_fmt; dst->n_sample = src->n_sample;
+
+ dst->shared.m = dst->shared.l = src->shared.l;
+ dst->shared.s = (char*) malloc(dst->shared.l);
+ memcpy(dst->shared.s,src->shared.s,dst->shared.l);
+
+ dst->indiv.m = dst->indiv.l = src->indiv.l;
+ dst->indiv.s = (char*) malloc(dst->indiv.l);
+ memcpy(dst->indiv.s,src->indiv.s,dst->indiv.l);
+
+ return dst;
+}
+bcf1_t *bcf_dup(bcf1_t *src)
+{
+ bcf1_t *out = bcf_init1();
+ return bcf_copy(out, src);
+}
+
+int bcf_write(htsFile *hfp, bcf_hdr_t *h, bcf1_t *v)
+{
+ if ( h->dirty ) bcf_hdr_sync(h);
+ if ( bcf_hdr_nsamples(h)!=v->n_sample )
+ {
+ fprintf(stderr,"[%s:%d %s] Broken VCF record, the number of columns at %s:%d does not match the number of samples (%d vs %d).\n",
+ __FILE__,__LINE__,__FUNCTION__,bcf_seqname(h,v),v->pos+1, v->n_sample,bcf_hdr_nsamples(h));
+ return -1;
+ }
+
+ if ( hfp->format.format == vcf || hfp->format.format == text_format )
+ return vcf_write(hfp,h,v);
+
+ if ( v->errcode )
+ {
+ // vcf_parse1() encountered a new contig or tag, undeclared in the
+ // header. At this point, the header must have been printed,
+ // proceeding would lead to a broken BCF file. Errors must be checked
+ // and cleared by the caller before we can proceed.
+ fprintf(stderr,"[%s:%d %s] Unchecked error (%d), exiting.\n", __FILE__,__LINE__,__FUNCTION__,v->errcode);
+ exit(1);
+ }
+ bcf1_sync(v); // check if the BCF record was modified
+
+ BGZF *fp = hfp->fp.bgzf;
+ uint32_t x[8];
+ x[0] = v->shared.l + 24; // to include six 32-bit integers
+ x[1] = v->indiv.l;
+ memcpy(x + 2, v, 16);
+ x[6] = (uint32_t)v->n_allele<<16 | v->n_info;
+ x[7] = (uint32_t)v->n_fmt<<24 | v->n_sample;
+ if ( bgzf_write(fp, x, 32) != 32 ) return -1;
+ if ( bgzf_write(fp, v->shared.s, v->shared.l) != v->shared.l ) return -1;
+ if ( bgzf_write(fp, v->indiv.s, v->indiv.l) != v->indiv.l ) return -1;
+ return 0;
+}
+
+/**********************
+ *** VCF header I/O ***
+ **********************/
+
+bcf_hdr_t *vcf_hdr_read(htsFile *fp)
+{
+ kstring_t txt, *s = &fp->line;
+ bcf_hdr_t *h;
+ h = bcf_hdr_init("r");
+ if (!h) {
+ fprintf(stderr, "[E::%s] failed to allocate bcf header\n", __func__);
+ return NULL;
+ }
+ txt.l = txt.m = 0; txt.s = 0;
+ while (hts_getline(fp, KS_SEP_LINE, s) >= 0) {
+ if (s->l == 0) continue;
+ if (s->s[0] != '#') {
+ if (hts_verbose >= 2)
+ fprintf(stderr, "[E::%s] no sample line\n", __func__);
+ free(txt.s);
+ bcf_hdr_destroy(h);
+ return NULL;
+ }
+ if (s->s[1] != '#' && fp->fn_aux) { // insert contigs here
+ int dret;
+ gzFile f;
+ kstream_t *ks;
+ kstring_t tmp;
+ tmp.l = tmp.m = 0; tmp.s = 0;
+ f = gzopen(fp->fn_aux, "r");
+ ks = ks_init(f);
+ while (ks_getuntil(ks, 0, &tmp, &dret) >= 0) {
+ int c;
+ kputs("##contig=<ID=", &txt); kputs(tmp.s, &txt);
+ ks_getuntil(ks, 0, &tmp, &dret);
+ kputs(",length=", &txt); kputw(atol(tmp.s), &txt);
+ kputsn(">\n", 2, &txt);
+ if (dret != '\n')
+ while ((c = ks_getc(ks)) != '\n' && c != -1); // skip the rest of the line
+ }
+ free(tmp.s);
+ ks_destroy(ks);
+ gzclose(f);
+ }
+ kputsn(s->s, s->l, &txt);
+ kputc('\n', &txt);
+ if (s->s[1] != '#') break;
+ }
+ if ( !txt.s )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not read the header\n", __FILE__,__LINE__,__FUNCTION__);
+ return NULL;
+ }
+ bcf_hdr_parse(h, txt.s);
+
+ // check tabix index, are all contigs listed in the header? add the missing ones
+ tbx_t *idx = tbx_index_load(fp->fn);
+ if ( idx )
+ {
+ int i, n, need_sync = 0;
+ const char **names = tbx_seqnames(idx, &n);
+ for (i=0; i<n; i++)
+ {
+ bcf_hrec_t *hrec = bcf_hdr_get_hrec(h, BCF_HL_CTG, "ID", (char*) names[i], NULL);
+ if ( hrec ) continue;
+ hrec = (bcf_hrec_t*) calloc(1,sizeof(bcf_hrec_t));
+ hrec->key = strdup("contig");
+ bcf_hrec_add_key(hrec, "ID", strlen("ID"));
+ bcf_hrec_set_val(hrec, hrec->nkeys-1, (char*) names[i], strlen(names[i]), 0);
+ bcf_hdr_add_hrec(h, hrec);
+ need_sync = 1;
+ }
+ free(names);
+ tbx_destroy(idx);
+ if ( need_sync )
+ bcf_hdr_sync(h);
+ }
+ free(txt.s);
+ return h;
+}
+
+int bcf_hdr_set(bcf_hdr_t *hdr, const char *fname)
+{
+ int i, n;
+ char **lines = hts_readlines(fname, &n);
+ if ( !lines ) return 1;
+ for (i=0; i<n-1; i++)
+ {
+ int k;
+ bcf_hrec_t *hrec = bcf_hdr_parse_line(hdr,lines[i],&k);
+ if ( hrec ) bcf_hdr_add_hrec(hdr, hrec);
+ free(lines[i]);
+ }
+ bcf_hdr_parse_sample_line(hdr,lines[n-1]);
+ free(lines[n-1]);
+ free(lines);
+ bcf_hdr_sync(hdr);
+ return 0;
+}
+
+static void _bcf_hrec_format(const bcf_hrec_t *hrec, int is_bcf, kstring_t *str)
+{
+ if ( !hrec->value )
+ {
+ int j, nout = 0;
+ ksprintf(str, "##%s=<", hrec->key);
+ for (j=0; j<hrec->nkeys; j++)
+ {
+ // do not output IDX if output is VCF
+ if ( !is_bcf && !strcmp("IDX",hrec->keys[j]) ) continue;
+ if ( nout ) kputc(',',str);
+ ksprintf(str,"%s=%s", hrec->keys[j], hrec->vals[j]);
+ nout++;
+ }
+ ksprintf(str,">\n");
+ }
+ else
+ ksprintf(str,"##%s=%s\n", hrec->key,hrec->value);
+}
+
+void bcf_hrec_format(const bcf_hrec_t *hrec, kstring_t *str)
+{
+ _bcf_hrec_format(hrec,0,str);
+}
+char *bcf_hdr_fmt_text(const bcf_hdr_t *hdr, int is_bcf, int *len)
+{
+ int i;
+ kstring_t txt = {0,0,0};
+ for (i=0; i<hdr->nhrec; i++)
+ _bcf_hrec_format(hdr->hrec[i], is_bcf, &txt);
+
+ ksprintf(&txt,"#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO");
+ if ( bcf_hdr_nsamples(hdr) )
+ {
+ ksprintf(&txt,"\tFORMAT");
+ for (i=0; i<bcf_hdr_nsamples(hdr); i++)
+ ksprintf(&txt,"\t%s", hdr->samples[i]);
+ }
+ ksprintf(&txt,"\n");
+
+ if ( len ) *len = txt.l;
+ return txt.s;
+}
+
+const char **bcf_hdr_seqnames(const bcf_hdr_t *h, int *n)
+{
+ vdict_t *d = (vdict_t*)h->dict[BCF_DT_CTG];
+ int tid, m = kh_size(d);
+ const char **names = (const char**) calloc(m,sizeof(const char*));
+ khint_t k;
+ for (k=kh_begin(d); k<kh_end(d); k++)
+ {
+ if ( !kh_exist(d,k) ) continue;
+ tid = kh_val(d,k).id;
+ assert( tid<m );
+ names[tid] = kh_key(d,k);
+ }
+ // sanity check: there should be no gaps
+ for (tid=0; tid<m; tid++)
+ assert(names[tid]);
+ *n = m;
+ return names;
+}
+
+int vcf_hdr_write(htsFile *fp, const bcf_hdr_t *h)
+{
+ int hlen;
+ char *htxt = bcf_hdr_fmt_text(h, 0, &hlen);
+ while (hlen && htxt[hlen-1] == 0) --hlen; // kill trailing zeros
+ int ret;
+ if ( fp->format.compression!=no_compression )
+ ret = bgzf_write(fp->fp.bgzf, htxt, hlen);
+ else
+ ret = hwrite(fp->fp.hfile, htxt, hlen);
+ free(htxt);
+ return ret<0 ? -1 : 0;
+}
+
+/***********************
+ *** Typed value I/O ***
+ ***********************/
+
+void bcf_enc_vint(kstring_t *s, int n, int32_t *a, int wsize)
+{
+ int32_t max = INT32_MIN + 1, min = INT32_MAX;
+ int i;
+ if (n == 0) bcf_enc_size(s, 0, BCF_BT_NULL);
+ else if (n == 1) bcf_enc_int1(s, a[0]);
+ else {
+ if (wsize <= 0) wsize = n;
+ for (i = 0; i < n; ++i) {
+ if (a[i] == bcf_int32_missing || a[i] == bcf_int32_vector_end ) continue;
+ if (max < a[i]) max = a[i];
+ if (min > a[i]) min = a[i];
+ }
+ if (max <= INT8_MAX && min > bcf_int8_vector_end) {
+ bcf_enc_size(s, wsize, BCF_BT_INT8);
+ for (i = 0; i < n; ++i)
+ if ( a[i]==bcf_int32_vector_end ) kputc(bcf_int8_vector_end, s);
+ else if ( a[i]==bcf_int32_missing ) kputc(bcf_int8_missing, s);
+ else kputc(a[i], s);
+ } else if (max <= INT16_MAX && min > bcf_int16_vector_end) {
+ bcf_enc_size(s, wsize, BCF_BT_INT16);
+ for (i = 0; i < n; ++i)
+ {
+ int16_t x;
+ if ( a[i]==bcf_int32_vector_end ) x = bcf_int16_vector_end;
+ else if ( a[i]==bcf_int32_missing ) x = bcf_int16_missing;
+ else x = a[i];
+ kputsn((char*)&x, 2, s);
+ }
+ } else {
+ bcf_enc_size(s, wsize, BCF_BT_INT32);
+ for (i = 0; i < n; ++i) {
+ int32_t x = a[i];
+ kputsn((char*)&x, 4, s);
+ }
+ }
+ }
+}
+
+void bcf_enc_vfloat(kstring_t *s, int n, float *a)
+{
+ bcf_enc_size(s, n, BCF_BT_FLOAT);
+ kputsn((char*)a, n << 2, s);
+}
+
+void bcf_enc_vchar(kstring_t *s, int l, const char *a)
+{
+ bcf_enc_size(s, l, BCF_BT_CHAR);
+ kputsn(a, l, s);
+}
+
+void bcf_fmt_array(kstring_t *s, int n, int type, void *data)
+{
+ int j = 0;
+ if (n == 0) {
+ kputc('.', s);
+ return;
+ }
+ if (type == BCF_BT_CHAR)
+ {
+ char *p = (char*)data;
+ for (j = 0; j < n && *p; ++j, ++p)
+ {
+ if ( *p==bcf_str_missing ) kputc('.', s);
+ else kputc(*p, s);
+ }
+ }
+ else
+ {
+ #define BRANCH(type_t, is_missing, is_vector_end, kprint) { \
+ type_t *p = (type_t *) data; \
+ for (j=0; j<n; j++) \
+ { \
+ if ( is_vector_end ) break; \
+ if ( j ) kputc(',', s); \
+ if ( is_missing ) kputc('.', s); \
+ else kprint; \
+ } \
+ }
+ switch (type) {
+ case BCF_BT_INT8: BRANCH(int8_t, p[j]==bcf_int8_missing, p[j]==bcf_int8_vector_end, kputw(p[j], s)); break;
+ case BCF_BT_INT16: BRANCH(int16_t, p[j]==bcf_int16_missing, p[j]==bcf_int16_vector_end, kputw(p[j], s)); break;
+ case BCF_BT_INT32: BRANCH(int32_t, p[j]==bcf_int32_missing, p[j]==bcf_int32_vector_end, kputw(p[j], s)); break;
+ case BCF_BT_FLOAT: BRANCH(float, bcf_float_is_missing(p[j]), bcf_float_is_vector_end(p[j]), ksprintf(s, "%g", p[j])); break;
+ default: fprintf(stderr,"todo: type %d\n", type); exit(1); break;
+ }
+ #undef BRANCH
+ }
+}
+
+uint8_t *bcf_fmt_sized_array(kstring_t *s, uint8_t *ptr)
+{
+ int x, type;
+ x = bcf_dec_size(ptr, &ptr, &type);
+ bcf_fmt_array(s, x, type, ptr);
+ return ptr + (x << bcf_type_shift[type]);
+}
+
+/********************
+ *** VCF site I/O ***
+ ********************/
+
+typedef struct {
+ int key, max_m, size, offset;
+ uint64_t is_gt:1, max_g:31, max_l:32;
+ uint32_t y;
+ uint8_t *buf;
+} fmt_aux_t;
+
+static inline void align_mem(kstring_t *s)
+{
+ if (s->l&7) {
+ uint64_t zero = 0;
+ int l = ((s->l + 7)>>3<<3) - s->l;
+ kputsn((char*)&zero, l, s);
+ }
+}
+
+// p,q is the start and the end of the FORMAT field
+#define MAX_N_FMT 255 /* Limited by size of bcf1_t n_fmt field */
+static int vcf_parse_format(kstring_t *s, const bcf_hdr_t *h, bcf1_t *v, char *p, char *q)
+{
+ if ( !bcf_hdr_nsamples(h) ) return 0;
+
+ char *r, *t;
+ int j, l, m, g;
+ khint_t k;
+ ks_tokaux_t aux1;
+ vdict_t *d = (vdict_t*)h->dict[BCF_DT_ID];
+ kstring_t *mem = (kstring_t*)&h->mem;
+ fmt_aux_t fmt[MAX_N_FMT];
+ mem->l = 0;
+
+ char *end = s->s + s->l;
+ if ( q>=end )
+ {
+ fprintf(stderr,"[%s:%d %s] Error: FORMAT column with no sample columns starting at %s:%d\n", __FILE__,__LINE__,__FUNCTION__,s->s,v->pos+1);
+ return -1;
+ }
+
+ // get format information from the dictionary
+ v->n_fmt = 0;
+ for (j = 0, t = kstrtok(p, ":", &aux1); t; t = kstrtok(0, 0, &aux1), ++j) {
+ if (j >= MAX_N_FMT) {
+ v->errcode |= BCF_ERR_LIMITS;
+ fprintf(stderr,"[E::%s] Error: FORMAT column at %s:%d lists more identifiers than htslib can handle.\n", __func__, bcf_seqname(h,v), v->pos+1);
+ return -1;
+ }
+
+ *(char*)aux1.p = 0;
+ k = kh_get(vdict, d, t);
+ if (k == kh_end(d) || kh_val(d, k).info[BCF_HL_FMT] == 15) {
+ if (hts_verbose >= 2) fprintf(stderr, "[W::%s] FORMAT '%s' is not defined in the header, assuming Type=String\n", __func__, t);
+ kstring_t tmp = {0,0,0};
+ int l;
+ ksprintf(&tmp, "##FORMAT=<ID=%s,Number=1,Type=String,Description=\"Dummy\">", t);
+ bcf_hrec_t *hrec = bcf_hdr_parse_line(h,tmp.s,&l);
+ free(tmp.s);
+ if ( bcf_hdr_add_hrec((bcf_hdr_t*)h, hrec) ) bcf_hdr_sync((bcf_hdr_t*)h);
+ k = kh_get(vdict, d, t);
+ v->errcode = BCF_ERR_TAG_UNDEF;
+ if (k == kh_end(d)) {
+ fprintf(stderr, "[E::%s] Could not add dummy header for FORMAT '%s'\n", __func__, t);
+ v->errcode |= BCF_ERR_TAG_INVALID;
+ return -1;
+ }
+ }
+ fmt[j].max_l = fmt[j].max_m = fmt[j].max_g = 0;
+ fmt[j].key = kh_val(d, k).id;
+ fmt[j].is_gt = !strcmp(t, "GT");
+ fmt[j].y = h->id[0][fmt[j].key].val->info[BCF_HL_FMT];
+ v->n_fmt++;
+ }
+ // compute max
+ int n_sample_ori = -1;
+ r = q + 1; // r: position in the format string
+ l = 0, m = g = 1, v->n_sample = 0; // m: max vector size, l: max field len, g: max number of alleles
+ while ( r<end )
+ {
+ // can we skip some samples?
+ if ( h->keep_samples )
+ {
+ n_sample_ori++;
+ if ( !bit_array_test(h->keep_samples,n_sample_ori) )
+ {
+ while ( *r!='\t' && r<end ) r++;
+ if ( *r=='\t' ) { *r = 0; r++; }
+ continue;
+ }
+ }
+
+ // collect fmt stats: max vector size, length, number of alleles
+ j = 0; // j-th format field
+ for (;;)
+ {
+ if ( *r == '\t' ) *r = 0;
+ if ( *r == ':' || !*r ) // end of field or end of sample
+ {
+ if (fmt[j].max_m < m) fmt[j].max_m = m;
+ if (fmt[j].max_l < l) fmt[j].max_l = l;
+ if (fmt[j].is_gt && fmt[j].max_g < g) fmt[j].max_g = g;
+ l = 0, m = g = 1;
+ if ( *r==':' )
+ {
+ j++;
+ if ( j>=v->n_fmt )
+ {
+ fprintf(stderr,"Incorrect number of FORMAT fields at %s:%d\n", h->id[BCF_DT_CTG][v->rid].key,v->pos+1);
+ exit(1);
+ }
+ }
+ else break;
+ }
+ else if ( *r== ',' ) m++;
+ else if ( fmt[j].is_gt && (*r == '|' || *r == '/') ) g++;
+ if ( r>=end ) break;
+ r++; l++;
+ }
+ v->n_sample++;
+ if ( v->n_sample == bcf_hdr_nsamples(h) ) break;
+ r++;
+ }
+
+ // allocate memory for arrays
+ for (j = 0; j < v->n_fmt; ++j) {
+ fmt_aux_t *f = &fmt[j];
+ if ( !f->max_m ) f->max_m = 1; // omitted trailing format field
+ if ((f->y>>4&0xf) == BCF_HT_STR) {
+ f->size = f->is_gt? f->max_g << 2 : f->max_l;
+ } else if ((f->y>>4&0xf) == BCF_HT_REAL || (f->y>>4&0xf) == BCF_HT_INT) {
+ f->size = f->max_m << 2;
+ } else
+ {
+ fprintf(stderr, "[E::%s] the format type %d currently not supported\n", __func__, f->y>>4&0xf);
+ abort(); // I do not know how to do with Flag in the genotype fields
+ }
+ align_mem(mem);
+ f->offset = mem->l;
+ ks_resize(mem, mem->l + v->n_sample * f->size);
+ mem->l += v->n_sample * f->size;
+ }
+ for (j = 0; j < v->n_fmt; ++j)
+ fmt[j].buf = (uint8_t*)mem->s + fmt[j].offset;
+ // fill the sample fields; at beginning of the loop, t points to the first char of a format
+ n_sample_ori = -1;
+ t = q + 1; m = 0; // m: sample id
+ while ( t<end )
+ {
+ // can we skip some samples?
+ if ( h->keep_samples )
+ {
+ n_sample_ori++;
+ if ( !bit_array_test(h->keep_samples,n_sample_ori) )
+ {
+ while ( *t && t<end ) t++;
+ t++;
+ continue;
+ }
+ }
+ if ( m == bcf_hdr_nsamples(h) ) break;
+
+ j = 0; // j-th format field, m-th sample
+ while ( t < end )
+ {
+ fmt_aux_t *z = &fmt[j++];
+ if ((z->y>>4&0xf) == BCF_HT_STR) {
+ if (z->is_gt) { // genotypes
+ int32_t is_phased = 0, *x = (int32_t*)(z->buf + z->size * m);
+ for (l = 0;; ++t) {
+ if (*t == '.') ++t, x[l++] = is_phased;
+ else x[l++] = (strtol(t, &t, 10) + 1) << 1 | is_phased;
+#if THOROUGH_SANITY_CHECKS
+ assert( 0 ); // success of strtol,strtod not checked
+#endif
+ is_phased = (*t == '|');
+ if (*t != '|' && *t != '/') break;
+ }
+ if ( !l ) x[l++] = 0; // An empty field, insert missing value
+ for (; l < z->size>>2; ++l) x[l] = bcf_int32_vector_end;
+ } else {
+ char *x = (char*)z->buf + z->size * m;
+ for (r = t, l = 0; *t != ':' && *t; ++t) x[l++] = *t;
+ for (; l < z->size; ++l) x[l] = 0;
+ }
+ } else if ((z->y>>4&0xf) == BCF_HT_INT) {
+ int32_t *x = (int32_t*)(z->buf + z->size * m);
+ for (l = 0;; ++t) {
+ if (*t == '.') x[l++] = bcf_int32_missing, ++t; // ++t to skip "."
+ else x[l++] = strtol(t, &t, 10);
+ if (*t != ',') break;
+ }
+ if ( !l ) x[l++] = bcf_int32_missing;
+ for (; l < z->size>>2; ++l) x[l] = bcf_int32_vector_end;
+ } else if ((z->y>>4&0xf) == BCF_HT_REAL) {
+ float *x = (float*)(z->buf + z->size * m);
+ for (l = 0;; ++t) {
+ if (*t == '.' && !isdigit(t[1])) bcf_float_set_missing(x[l++]), ++t; // ++t to skip "."
+ else x[l++] = strtod(t, &t);
+ if (*t != ',') break;
+ }
+ if ( !l ) bcf_float_set_missing(x[l++]); // An empty field, insert missing value
+ for (; l < z->size>>2; ++l) bcf_float_set_vector_end(x[l]);
+ } else abort();
+
+ if (*t == '\0') {
+ break;
+ }
+ else if (*t == ':') {
+ t++;
+ }
+ else {
+ char buffer[8];
+ fprintf(stderr,"[E::%s] Invalid character '%s' in '%s' FORMAT field at %s:%d\n", __FUNCTION__, dump_char(buffer, *t), h->id[BCF_DT_ID][z->key].key, bcf_seqname(h,v), v->pos+1);
+ v->errcode |= BCF_ERR_CHAR;
+ return -1;
+ }
+ }
+
+ for (; j < v->n_fmt; ++j) { // fill end-of-vector values
+ fmt_aux_t *z = &fmt[j];
+ if ((z->y>>4&0xf) == BCF_HT_STR) {
+ if (z->is_gt) {
+ int32_t *x = (int32_t*)(z->buf + z->size * m);
+ if (z->size) x[0] = bcf_int32_missing;
+ for (l = 1; l < z->size>>2; ++l) x[l] = bcf_int32_vector_end;
+ } else {
+ char *x = (char*)z->buf + z->size * m;
+ if ( z->size ) x[0] = '.';
+ for (l = 1; l < z->size; ++l) x[l] = 0;
+ }
+ } else if ((z->y>>4&0xf) == BCF_HT_INT) {
+ int32_t *x = (int32_t*)(z->buf + z->size * m);
+ x[0] = bcf_int32_missing;
+ for (l = 1; l < z->size>>2; ++l) x[l] = bcf_int32_vector_end;
+ } else if ((z->y>>4&0xf) == BCF_HT_REAL) {
+ float *x = (float*)(z->buf + z->size * m);
+ bcf_float_set_missing(x[0]);
+ for (l = 1; l < z->size>>2; ++l) bcf_float_set_vector_end(x[l]);
+ }
+ }
+
+ m++; t++;
+ }
+
+ // write individual genotype information
+ kstring_t *str = &v->indiv;
+ int i;
+ if (v->n_sample > 0) {
+ for (i = 0; i < v->n_fmt; ++i) {
+ fmt_aux_t *z = &fmt[i];
+ bcf_enc_int1(str, z->key);
+ if ((z->y>>4&0xf) == BCF_HT_STR && !z->is_gt) {
+ bcf_enc_size(str, z->size, BCF_BT_CHAR);
+ kputsn((char*)z->buf, z->size * v->n_sample, str);
+ } else if ((z->y>>4&0xf) == BCF_HT_INT || z->is_gt) {
+ bcf_enc_vint(str, (z->size>>2) * v->n_sample, (int32_t*)z->buf, z->size>>2);
+ } else {
+ bcf_enc_size(str, z->size>>2, BCF_BT_FLOAT);
+ kputsn((char*)z->buf, z->size * v->n_sample, str);
+ }
+ }
+ }
+
+ if ( v->n_sample!=bcf_hdr_nsamples(h) )
+ {
+ fprintf(stderr,"[%s:%d %s] Number of columns at %s:%d does not match the number of samples (%d vs %d).\n",
+ __FILE__,__LINE__,__FUNCTION__,bcf_seqname(h,v),v->pos+1, v->n_sample,bcf_hdr_nsamples(h));
+ v->errcode |= BCF_ERR_NCOLS;
+ return -1;
+ }
+ if ( v->indiv.l > 0xffffffff )
+ {
+ fprintf(stderr,"[%s:%d %s] The FORMAT at %s:%d is too long...\n",
+ __FILE__,__LINE__,__FUNCTION__,bcf_seqname(h,v),v->pos+1);
+ v->errcode |= BCF_ERR_LIMITS;
+
+ // Error recovery: return -1 if this is a critical error or 0 if we want to ignore the FORMAT and proceed
+ v->n_fmt = 0;
+ return -1;
+ }
+
+ return 0;
+}
+
+int vcf_parse(kstring_t *s, const bcf_hdr_t *h, bcf1_t *v)
+{
+ int i = 0;
+ char *p, *q, *r, *t;
+ kstring_t *str;
+ khint_t k;
+ ks_tokaux_t aux;
+
+ bcf_clear1(v);
+ str = &v->shared;
+ memset(&aux, 0, sizeof(ks_tokaux_t));
+ for (p = kstrtok(s->s, "\t", &aux), i = 0; p; p = kstrtok(0, 0, &aux), ++i) {
+ q = (char*)aux.p;
+ *q = 0;
+ if (i == 0) { // CHROM
+ vdict_t *d = (vdict_t*)h->dict[BCF_DT_CTG];
+ k = kh_get(vdict, d, p);
+ if (k == kh_end(d))
+ {
+ // Simple error recovery for chromosomes not defined in the header. It will not help when VCF header has
+ // been already printed, but will enable tools like vcfcheck to proceed.
+ if (hts_verbose >= 2) fprintf(stderr, "[W::%s] contig '%s' is not defined in the header. (Quick workaround: index the file with tabix.)\n", __func__, p);
+ kstring_t tmp = {0,0,0};
+ int l;
+ ksprintf(&tmp, "##contig=<ID=%s>", p);
+ bcf_hrec_t *hrec = bcf_hdr_parse_line(h,tmp.s,&l);
+ free(tmp.s);
+ if ( bcf_hdr_add_hrec((bcf_hdr_t*)h, hrec) ) bcf_hdr_sync((bcf_hdr_t*)h);
+ k = kh_get(vdict, d, p);
+ v->errcode = BCF_ERR_CTG_UNDEF;
+ if (k == kh_end(d)) {
+ fprintf(stderr, "[E::%s] Could not add dummy header for contig '%s'\n", __func__, p);
+ v->errcode |= BCF_ERR_CTG_INVALID;
+ return -1;
+ }
+ }
+ v->rid = kh_val(d, k).id;
+ } else if (i == 1) { // POS
+ v->pos = atoi(p) - 1;
+ } else if (i == 2) { // ID
+ if (strcmp(p, ".")) bcf_enc_vchar(str, q - p, p);
+ else bcf_enc_size(str, 0, BCF_BT_CHAR);
+ } else if (i == 3) { // REF
+ bcf_enc_vchar(str, q - p, p);
+ v->n_allele = 1, v->rlen = q - p;
+ } else if (i == 4) { // ALT
+ if (strcmp(p, ".")) {
+ for (r = t = p;; ++r) {
+ if (*r == ',' || *r == 0) {
+ bcf_enc_vchar(str, r - t, t);
+ t = r + 1;
+ ++v->n_allele;
+ }
+ if (r == q) break;
+ }
+ }
+ } else if (i == 5) { // QUAL
+ if (strcmp(p, ".")) v->qual = atof(p);
+ else memcpy(&v->qual, &bcf_float_missing, 4);
+ if ( v->max_unpack && !(v->max_unpack>>1) ) return 0; // BCF_UN_STR
+ } else if (i == 6) { // FILTER
+ if (strcmp(p, ".")) {
+ int32_t *a;
+ int n_flt = 1, i;
+ ks_tokaux_t aux1;
+ vdict_t *d = (vdict_t*)h->dict[BCF_DT_ID];
+ // count the number of filters
+ if (*(q-1) == ';') *(q-1) = 0;
+ for (r = p; *r; ++r)
+ if (*r == ';') ++n_flt;
+ a = (int32_t*)alloca(n_flt * sizeof(int32_t));
+ // add filters
+ for (t = kstrtok(p, ";", &aux1), i = 0; t; t = kstrtok(0, 0, &aux1)) {
+ *(char*)aux1.p = 0;
+ k = kh_get(vdict, d, t);
+ if (k == kh_end(d))
+ {
+ // Simple error recovery for FILTERs not defined in the header. It will not help when VCF header has
+ // been already printed, but will enable tools like vcfcheck to proceed.
+ if (hts_verbose >= 2) fprintf(stderr, "[W::%s] FILTER '%s' is not defined in the header\n", __func__, t);
+ kstring_t tmp = {0,0,0};
+ int l;
+ ksprintf(&tmp, "##FILTER=<ID=%s,Description=\"Dummy\">", t);
+ bcf_hrec_t *hrec = bcf_hdr_parse_line(h,tmp.s,&l);
+ free(tmp.s);
+ if ( bcf_hdr_add_hrec((bcf_hdr_t*)h, hrec) ) bcf_hdr_sync((bcf_hdr_t*)h);
+ k = kh_get(vdict, d, t);
+ v->errcode = BCF_ERR_TAG_UNDEF;
+ if (k == kh_end(d)) {
+ fprintf(stderr, "[E::%s] Could not add dummy header for FILTER '%s'\n", __func__, t);
+ v->errcode |= BCF_ERR_TAG_INVALID;
+ return -1;
+ }
+ }
+ a[i++] = kh_val(d, k).id;
+ }
+ n_flt = i;
+ bcf_enc_vint(str, n_flt, a, -1);
+ } else bcf_enc_vint(str, 0, 0, -1);
+ if ( v->max_unpack && !(v->max_unpack>>2) ) return 0; // BCF_UN_FLT
+ } else if (i == 7) { // INFO
+ char *key;
+ vdict_t *d = (vdict_t*)h->dict[BCF_DT_ID];
+ v->n_info = 0;
+ if (strcmp(p, ".")) {
+ if (*(q-1) == ';') *(q-1) = 0;
+ for (r = key = p;; ++r) {
+ int c;
+ char *val, *end;
+ if (*r != ';' && *r != '=' && *r != 0) continue;
+ val = end = 0;
+ c = *r; *r = 0;
+ if (c == '=') {
+ val = r + 1;
+ for (end = val; *end != ';' && *end != 0; ++end);
+ c = *end; *end = 0;
+ } else end = r;
+ if ( !*key ) { if (c==0) break; r = end; key = r + 1; continue; } // faulty VCF, ";;" in the INFO
+ k = kh_get(vdict, d, key);
+ if (k == kh_end(d) || kh_val(d, k).info[BCF_HL_INFO] == 15)
+ {
+ if (hts_verbose >= 2) fprintf(stderr, "[W::%s] INFO '%s' is not defined in the header, assuming Type=String\n", __func__, key);
+ kstring_t tmp = {0,0,0};
+ int l;
+ ksprintf(&tmp, "##INFO=<ID=%s,Number=1,Type=String,Description=\"Dummy\">", key);
+ bcf_hrec_t *hrec = bcf_hdr_parse_line(h,tmp.s,&l);
+ free(tmp.s);
+ if ( bcf_hdr_add_hrec((bcf_hdr_t*)h, hrec) ) bcf_hdr_sync((bcf_hdr_t*)h);
+ k = kh_get(vdict, d, key);
+ v->errcode = BCF_ERR_TAG_UNDEF;
+ if (k == kh_end(d)) {
+ fprintf(stderr, "[E::%s] Could not add dummy header for INFO '%s'\n", __func__, key);
+ v->errcode |= BCF_ERR_TAG_INVALID;
+ return -1;
+ }
+ }
+ uint32_t y = kh_val(d, k).info[BCF_HL_INFO];
+ ++v->n_info;
+ bcf_enc_int1(str, kh_val(d, k).id);
+ if (val == 0) {
+ bcf_enc_size(str, 0, BCF_BT_NULL);
+ } else if ((y>>4&0xf) == BCF_HT_FLAG || (y>>4&0xf) == BCF_HT_STR) { // if Flag has a value, treat it as a string
+ bcf_enc_vchar(str, end - val, val);
+ } else { // int/float value/array
+ int i, n_val;
+ char *t, *te;
+ for (t = val, n_val = 1; *t; ++t) // count the number of values
+ if (*t == ',') ++n_val;
+ if ((y>>4&0xf) == BCF_HT_INT) {
+ int32_t *z;
+ z = (int32_t*)alloca(n_val * sizeof(int32_t));
+ for (i = 0, t = val; i < n_val; ++i, ++t)
+ {
+ z[i] = strtol(t, &te, 10);
+ if ( te==t ) // conversion failed
+ {
+ z[i] = bcf_int32_missing;
+ while ( *te && *te!=',' ) te++;
+ }
+ t = te;
+ }
+ bcf_enc_vint(str, n_val, z, -1);
+ if (strcmp(key, "END") == 0) v->rlen = z[0] - v->pos;
+ } else if ((y>>4&0xf) == BCF_HT_REAL) {
+ float *z;
+ z = (float*)alloca(n_val * sizeof(float));
+ for (i = 0, t = val; i < n_val; ++i, ++t)
+ {
+ z[i] = strtod(t, &te);
+ if ( te==t ) // conversion failed
+ {
+ bcf_float_set_missing(z[i]);
+ while ( *te && *te!=',' ) te++;
+ }
+ t = te;
+ }
+ bcf_enc_vfloat(str, n_val, z);
+ }
+ }
+ if (c == 0) break;
+ r = end;
+ key = r + 1;
+ }
+ }
+ if ( v->max_unpack && !(v->max_unpack>>3) ) return 0;
+ } else if (i == 8) // FORMAT
+ return vcf_parse_format(s, h, v, p, q);
+ }
+ return 0;
+}
+
+int vcf_read(htsFile *fp, const bcf_hdr_t *h, bcf1_t *v)
+{
+ int ret;
+ ret = hts_getline(fp, KS_SEP_LINE, &fp->line);
+ if (ret < 0) return -1;
+ return vcf_parse1(&fp->line, h, v);
+}
+
+static inline uint8_t *bcf_unpack_fmt_core1(uint8_t *ptr, int n_sample, bcf_fmt_t *fmt)
+{
+ uint8_t *ptr_start = ptr;
+ fmt->id = bcf_dec_typed_int1(ptr, &ptr);
+ fmt->n = bcf_dec_size(ptr, &ptr, &fmt->type);
+ fmt->size = fmt->n << bcf_type_shift[fmt->type];
+ fmt->p = ptr;
+ fmt->p_off = ptr - ptr_start;
+ fmt->p_free = 0;
+ ptr += n_sample * fmt->size;
+ fmt->p_len = ptr - fmt->p;
+ return ptr;
+}
+
+static inline uint8_t *bcf_unpack_info_core1(uint8_t *ptr, bcf_info_t *info)
+{
+ uint8_t *ptr_start = ptr;
+ info->key = bcf_dec_typed_int1(ptr, &ptr);
+ info->len = bcf_dec_size(ptr, &ptr, &info->type);
+ info->vptr = ptr;
+ info->vptr_off = ptr - ptr_start;
+ info->vptr_free = 0;
+ info->v1.i = 0;
+ if (info->len == 1) {
+ if (info->type == BCF_BT_INT8 || info->type == BCF_BT_CHAR) info->v1.i = *(int8_t*)ptr;
+ else if (info->type == BCF_BT_INT32) info->v1.i = *(int32_t*)ptr;
+ else if (info->type == BCF_BT_FLOAT) info->v1.f = *(float*)ptr;
+ else if (info->type == BCF_BT_INT16) info->v1.i = *(int16_t*)ptr;
+ }
+ ptr += info->len << bcf_type_shift[info->type];
+ info->vptr_len = ptr - info->vptr;
+ return ptr;
+}
+
+int bcf_unpack(bcf1_t *b, int which)
+{
+ if ( !b->shared.l ) return 0; // Building a new BCF record from scratch
+ uint8_t *ptr = (uint8_t*)b->shared.s, *ptr_ori;
+ int *offset, i;
+ bcf_dec_t *d = &b->d;
+ if (which & BCF_UN_FLT) which |= BCF_UN_STR;
+ if (which & BCF_UN_INFO) which |= BCF_UN_SHR;
+ if ((which&BCF_UN_STR) && !(b->unpacked&BCF_UN_STR))
+ {
+ kstring_t tmp;
+
+ // ID
+ tmp.l = 0; tmp.s = d->id; tmp.m = d->m_id;
+ ptr_ori = ptr;
+ ptr = bcf_fmt_sized_array(&tmp, ptr);
+ b->unpack_size[0] = ptr - ptr_ori;
+ kputc('\0', &tmp);
+ d->id = tmp.s; d->m_id = tmp.m;
+
+ // REF and ALT are in a single block (d->als) and d->alleles are pointers into this block
+ tmp.l = 0; tmp.s = d->als; tmp.m = d->m_als;
+ offset = (int*)alloca(b->n_allele * sizeof(int));
+ ptr_ori = ptr;
+ for (i = 0; i < b->n_allele; ++i) {
+ offset[i] = tmp.l;
+ ptr = bcf_fmt_sized_array(&tmp, ptr);
+ kputc('\0', &tmp);
+ }
+ b->unpack_size[1] = ptr - ptr_ori;
+ d->als = tmp.s; d->m_als = tmp.m;
+
+ hts_expand(char*, b->n_allele, d->m_allele, d->allele); // NM: hts_expand() is a macro
+ for (i = 0; i < b->n_allele; ++i)
+ d->allele[i] = d->als + offset[i];
+ b->unpacked |= BCF_UN_STR;
+ }
+ if ((which&BCF_UN_FLT) && !(b->unpacked&BCF_UN_FLT)) { // FILTER
+ ptr = (uint8_t*)b->shared.s + b->unpack_size[0] + b->unpack_size[1];
+ ptr_ori = ptr;
+ if (*ptr>>4) {
+ int type;
+ d->n_flt = bcf_dec_size(ptr, &ptr, &type);
+ hts_expand(int, d->n_flt, d->m_flt, d->flt);
+ for (i = 0; i < d->n_flt; ++i)
+ d->flt[i] = bcf_dec_int1(ptr, type, &ptr);
+ } else ++ptr, d->n_flt = 0;
+ b->unpack_size[2] = ptr - ptr_ori;
+ b->unpacked |= BCF_UN_FLT;
+ }
+ if ((which&BCF_UN_INFO) && !(b->unpacked&BCF_UN_INFO)) { // INFO
+ ptr = (uint8_t*)b->shared.s + b->unpack_size[0] + b->unpack_size[1] + b->unpack_size[2];
+ hts_expand(bcf_info_t, b->n_info, d->m_info, d->info);
+ for (i = 0; i < d->m_info; ++i) d->info[i].vptr_free = 0;
+ for (i = 0; i < b->n_info; ++i)
+ ptr = bcf_unpack_info_core1(ptr, &d->info[i]);
+ b->unpacked |= BCF_UN_INFO;
+ }
+ if ((which&BCF_UN_FMT) && b->n_sample && !(b->unpacked&BCF_UN_FMT)) { // FORMAT
+ ptr = (uint8_t*)b->indiv.s;
+ hts_expand(bcf_fmt_t, b->n_fmt, d->m_fmt, d->fmt);
+ for (i = 0; i < d->m_fmt; ++i) d->fmt[i].p_free = 0;
+ for (i = 0; i < b->n_fmt; ++i)
+ ptr = bcf_unpack_fmt_core1(ptr, b->n_sample, &d->fmt[i]);
+ b->unpacked |= BCF_UN_FMT;
+ }
+ return 0;
+}
+
+int vcf_format(const bcf_hdr_t *h, const bcf1_t *v, kstring_t *s)
+{
+ int i;
+ bcf_unpack((bcf1_t*)v, BCF_UN_ALL);
+ kputs(h->id[BCF_DT_CTG][v->rid].key, s); // CHROM
+ kputc('\t', s); kputw(v->pos + 1, s); // POS
+ kputc('\t', s); kputs(v->d.id ? v->d.id : ".", s); // ID
+ kputc('\t', s); // REF
+ if (v->n_allele > 0) kputs(v->d.allele[0], s);
+ else kputc('.', s);
+ kputc('\t', s); // ALT
+ if (v->n_allele > 1) {
+ for (i = 1; i < v->n_allele; ++i) {
+ if (i > 1) kputc(',', s);
+ kputs(v->d.allele[i], s);
+ }
+ } else kputc('.', s);
+ kputc('\t', s); // QUAL
+ if ( bcf_float_is_missing(v->qual) ) kputc('.', s); // QUAL
+ else ksprintf(s, "%g", v->qual);
+ kputc('\t', s); // FILTER
+ if (v->d.n_flt) {
+ for (i = 0; i < v->d.n_flt; ++i) {
+ if (i) kputc(';', s);
+ kputs(h->id[BCF_DT_ID][v->d.flt[i]].key, s);
+ }
+ } else kputc('.', s);
+ kputc('\t', s); // INFO
+ if (v->n_info) {
+ int first = 1;
+ for (i = 0; i < v->n_info; ++i) {
+ bcf_info_t *z = &v->d.info[i];
+ if ( !z->vptr ) continue;
+ if ( !first ) kputc(';', s);
+ first = 0;
+ kputs(h->id[BCF_DT_ID][z->key].key, s);
+ if (z->len <= 0) continue;
+ kputc('=', s);
+ if (z->len == 1)
+ {
+ switch (z->type)
+ {
+ case BCF_BT_INT8: if ( z->v1.i==bcf_int8_missing ) kputc('.', s); else kputw(z->v1.i, s); break;
+ case BCF_BT_INT16: if ( z->v1.i==bcf_int16_missing ) kputc('.', s); else kputw(z->v1.i, s); break;
+ case BCF_BT_INT32: if ( z->v1.i==bcf_int32_missing ) kputc('.', s); else kputw(z->v1.i, s); break;
+ case BCF_BT_FLOAT: if ( bcf_float_is_missing(z->v1.f) ) kputc('.', s); else ksprintf(s, "%g", z->v1.f); break;
+ case BCF_BT_CHAR: kputc(z->v1.i, s); break;
+ default: fprintf(stderr,"todo: type %d\n", z->type); exit(1); break;
+ }
+ }
+ else bcf_fmt_array(s, z->len, z->type, z->vptr);
+ }
+ if ( first ) kputc('.', s);
+ } else kputc('.', s);
+ // FORMAT and individual information
+ if (v->n_sample)
+ {
+ int i,j;
+ if ( v->n_fmt)
+ {
+ int gt_i = -1;
+ bcf_fmt_t *fmt = v->d.fmt;
+ int first = 1;
+ for (i = 0; i < (int)v->n_fmt; ++i) {
+ if ( !fmt[i].p ) continue;
+ kputc(!first ? ':' : '\t', s); first = 0;
+ if ( fmt[i].id<0 ) //!bcf_hdr_idinfo_exists(h,BCF_HL_FMT,fmt[i].id) )
+ {
+ fprintf(stderr, "[E::%s] invalid BCF, the FORMAT tag id=%d not present in the header.\n", __func__, fmt[i].id);
+ abort();
+ }
+ kputs(h->id[BCF_DT_ID][fmt[i].id].key, s);
+ if (strcmp(h->id[BCF_DT_ID][fmt[i].id].key, "GT") == 0) gt_i = i;
+ }
+ if ( first ) kputs("\t.", s);
+ for (j = 0; j < v->n_sample; ++j) {
+ kputc('\t', s);
+ first = 1;
+ for (i = 0; i < (int)v->n_fmt; ++i) {
+ bcf_fmt_t *f = &fmt[i];
+ if ( !f->p ) continue;
+ if (!first) kputc(':', s);
+ first = 0;
+ if (gt_i == i)
+ bcf_format_gt(f,j,s);
+ else
+ bcf_fmt_array(s, f->n, f->type, f->p + j * f->size);
+ }
+ if ( first ) kputc('.', s);
+ }
+ }
+ else
+ for (j=0; j<=v->n_sample; j++)
+ kputs("\t.", s);
+ }
+ kputc('\n', s);
+ return 0;
+}
+
+int vcf_write_line(htsFile *fp, kstring_t *line)
+{
+ int ret;
+ if ( line->s[line->l-1]!='\n' ) kputc('\n',line);
+ if ( fp->format.compression!=no_compression )
+ ret = bgzf_write(fp->fp.bgzf, line->s, line->l);
+ else
+ ret = hwrite(fp->fp.hfile, line->s, line->l);
+ return ret==line->l ? 0 : -1;
+}
+
+int vcf_write(htsFile *fp, const bcf_hdr_t *h, bcf1_t *v)
+{
+ int ret;
+ fp->line.l = 0;
+ vcf_format1(h, v, &fp->line);
+ if ( fp->format.compression!=no_compression )
+ ret = bgzf_write(fp->fp.bgzf, fp->line.s, fp->line.l);
+ else
+ ret = hwrite(fp->fp.hfile, fp->line.s, fp->line.l);
+ return ret==fp->line.l ? 0 : -1;
+}
+
+/************************
+ * Data access routines *
+ ************************/
+
+int bcf_hdr_id2int(const bcf_hdr_t *h, int which, const char *id)
+{
+ khint_t k;
+ vdict_t *d = (vdict_t*)h->dict[which];
+ k = kh_get(vdict, d, id);
+ return k == kh_end(d)? -1 : kh_val(d, k).id;
+}
+
+
+/********************
+ *** BCF indexing ***
+ ********************/
+
+hts_idx_t *bcf_index(htsFile *fp, int min_shift)
+{
+ int n_lvls, i;
+ bcf1_t *b;
+ hts_idx_t *idx;
+ bcf_hdr_t *h;
+ int64_t max_len = 0, s;
+ h = bcf_hdr_read(fp);
+ if ( !h ) return NULL;
+ int nids = 0;
+ for (i = 0; i < h->n[BCF_DT_CTG]; ++i)
+ {
+ if ( !h->id[BCF_DT_CTG][i].val ) continue;
+ if ( max_len < h->id[BCF_DT_CTG][i].val->info[0] ) max_len = h->id[BCF_DT_CTG][i].val->info[0];
+ nids++;
+ }
+ if ( !max_len ) max_len = ((int64_t)1<<31) - 1; // In case contig line is broken.
+ max_len += 256;
+ for (n_lvls = 0, s = 1<<min_shift; max_len > s; ++n_lvls, s <<= 3);
+ idx = hts_idx_init(nids, HTS_FMT_CSI, bgzf_tell(fp->fp.bgzf), min_shift, n_lvls);
+ b = bcf_init1();
+ while (bcf_read1(fp,h, b) >= 0) {
+ int ret;
+ ret = hts_idx_push(idx, b->rid, b->pos, b->pos + b->rlen, bgzf_tell(fp->fp.bgzf), 1);
+ if (ret < 0)
+ {
+ bcf_destroy1(b);
+ hts_idx_destroy(idx);
+ return NULL;
+ }
+ }
+ hts_idx_finish(idx, bgzf_tell(fp->fp.bgzf));
+ bcf_destroy1(b);
+ bcf_hdr_destroy(h);
+ return idx;
+}
+
+hts_idx_t *bcf_index_load2(const char *fn, const char *fnidx)
+{
+ return fnidx? hts_idx_load2(fn, fnidx) : bcf_index_load(fn);
+}
+
+int bcf_index_build2(const char *fn, const char *fnidx, int min_shift)
+{
+ htsFile *fp;
+ hts_idx_t *idx;
+ int ret;
+ if ((fp = hts_open(fn, "rb")) == 0) return -1;
+ if ( fp->format.compression!=bgzf ) { hts_close(fp); return -1; }
+ idx = bcf_index(fp, min_shift);
+ hts_close(fp);
+ if ( !idx ) return -1;
+ ret = hts_idx_save_as(idx, fn, fnidx, HTS_FMT_CSI);
+ hts_idx_destroy(idx);
+ return ret;
+}
+
+int bcf_index_build(const char *fn, int min_shift)
+{
+ return bcf_index_build2(fn, NULL, min_shift);
+}
+
+/*****************
+ *** Utilities ***
+ *****************/
+
+int bcf_hdr_combine(bcf_hdr_t *dst, const bcf_hdr_t *src)
+{
+ int i, ndst_ori = dst->nhrec, need_sync = 0, ret = 0;
+ for (i=0; i<src->nhrec; i++)
+ {
+ if ( src->hrec[i]->type==BCF_HL_GEN && src->hrec[i]->value )
+ {
+ int j;
+ for (j=0; j<ndst_ori; j++)
+ {
+ if ( dst->hrec[j]->type!=BCF_HL_GEN ) continue;
+
+ // Checking only the key part of generic lines, otherwise
+ // the VCFs are too verbose. Should we perhaps add a flag
+ // to bcf_hdr_combine() and make this optional?
+ if ( !strcmp(src->hrec[i]->key,dst->hrec[j]->key) ) break;
+ }
+ if ( j>=ndst_ori )
+ need_sync += bcf_hdr_add_hrec(dst, bcf_hrec_dup(src->hrec[i]));
+ }
+ else if ( src->hrec[i]->type==BCF_HL_STR )
+ {
+ // NB: we are ignoring fields without ID
+ int j = bcf_hrec_find_key(src->hrec[i],"ID");
+ if ( j>=0 )
+ {
+ bcf_hrec_t *rec = bcf_hdr_get_hrec(dst, src->hrec[i]->type, "ID", src->hrec[i]->vals[j], src->hrec[i]->key);
+ if ( !rec )
+ need_sync += bcf_hdr_add_hrec(dst, bcf_hrec_dup(src->hrec[i]));
+ }
+ }
+ else
+ {
+ int j = bcf_hrec_find_key(src->hrec[i],"ID");
+ assert( j>=0 ); // this should always be true for valid VCFs
+
+ bcf_hrec_t *rec = bcf_hdr_get_hrec(dst, src->hrec[i]->type, "ID", src->hrec[i]->vals[j], NULL);
+ if ( !rec )
+ need_sync += bcf_hdr_add_hrec(dst, bcf_hrec_dup(src->hrec[i]));
+ else if ( src->hrec[i]->type==BCF_HL_INFO || src->hrec[i]->type==BCF_HL_FMT )
+ {
+ // Check that both records are of the same type. The bcf_hdr_id2length
+ // macro cannot be used here because dst header is not synced yet.
+ vdict_t *d_src = (vdict_t*)src->dict[BCF_DT_ID];
+ vdict_t *d_dst = (vdict_t*)dst->dict[BCF_DT_ID];
+ khint_t k_src = kh_get(vdict, d_src, src->hrec[i]->vals[0]);
+ khint_t k_dst = kh_get(vdict, d_dst, src->hrec[i]->vals[0]);
+ if ( (kh_val(d_src,k_src).info[rec->type]>>8 & 0xf) != (kh_val(d_dst,k_dst).info[rec->type]>>8 & 0xf) )
+ {
+ fprintf(stderr,"Warning: trying to combine \"%s\" tag definitions of different lengths\n", src->hrec[i]->vals[0]);
+ ret |= 1;
+ }
+ if ( (kh_val(d_src,k_src).info[rec->type]>>4 & 0xf) != (kh_val(d_dst,k_dst).info[rec->type]>>4 & 0xf) )
+ {
+ fprintf(stderr,"Warning: trying to combine \"%s\" tag definitions of different types\n", src->hrec[i]->vals[0]);
+ ret |= 1;
+ }
+ }
+ }
+ }
+ if ( need_sync ) bcf_hdr_sync(dst);
+ return ret;
+}
+
+bcf_hdr_t *bcf_hdr_merge(bcf_hdr_t *dst, const bcf_hdr_t *src)
+{
+ if ( !dst )
+ {
+ // this will effectively strip existing IDX attributes from src to become dst
+ dst = bcf_hdr_init("r");
+ char *htxt = bcf_hdr_fmt_text(src, 0, NULL);
+ bcf_hdr_parse(dst, htxt);
+ free(htxt);
+ return dst;
+ }
+
+ int i, ndst_ori = dst->nhrec, need_sync = 0, ret = 0;
+ for (i=0; i<src->nhrec; i++)
+ {
+ if ( src->hrec[i]->type==BCF_HL_GEN && src->hrec[i]->value )
+ {
+ int j;
+ for (j=0; j<ndst_ori; j++)
+ {
+ if ( dst->hrec[j]->type!=BCF_HL_GEN ) continue;
+
+ // Checking only the key part of generic lines, otherwise
+ // the VCFs are too verbose. Should we perhaps add a flag
+ // to bcf_hdr_combine() and make this optional?
+ if ( !strcmp(src->hrec[i]->key,dst->hrec[j]->key) ) break;
+ }
+ if ( j>=ndst_ori )
+ need_sync += bcf_hdr_add_hrec(dst, bcf_hrec_dup(src->hrec[i]));
+ }
+ else if ( src->hrec[i]->type==BCF_HL_STR )
+ {
+ // NB: we are ignoring fields without ID
+ int j = bcf_hrec_find_key(src->hrec[i],"ID");
+ if ( j>=0 )
+ {
+ bcf_hrec_t *rec = bcf_hdr_get_hrec(dst, src->hrec[i]->type, "ID", src->hrec[i]->vals[j], src->hrec[i]->key);
+ if ( !rec )
+ need_sync += bcf_hdr_add_hrec(dst, bcf_hrec_dup(src->hrec[i]));
+ }
+ }
+ else
+ {
+ int j = bcf_hrec_find_key(src->hrec[i],"ID");
+ assert( j>=0 ); // this should always be true for valid VCFs
+
+ bcf_hrec_t *rec = bcf_hdr_get_hrec(dst, src->hrec[i]->type, "ID", src->hrec[i]->vals[j], NULL);
+ if ( !rec )
+ need_sync += bcf_hdr_add_hrec(dst, bcf_hrec_dup(src->hrec[i]));
+ else if ( src->hrec[i]->type==BCF_HL_INFO || src->hrec[i]->type==BCF_HL_FMT )
+ {
+ // Check that both records are of the same type. The bcf_hdr_id2length
+ // macro cannot be used here because dst header is not synced yet.
+ vdict_t *d_src = (vdict_t*)src->dict[BCF_DT_ID];
+ vdict_t *d_dst = (vdict_t*)dst->dict[BCF_DT_ID];
+ khint_t k_src = kh_get(vdict, d_src, src->hrec[i]->vals[0]);
+ khint_t k_dst = kh_get(vdict, d_dst, src->hrec[i]->vals[0]);
+ if ( (kh_val(d_src,k_src).info[rec->type]>>8 & 0xf) != (kh_val(d_dst,k_dst).info[rec->type]>>8 & 0xf) )
+ {
+ fprintf(stderr,"Warning: trying to combine \"%s\" tag definitions of different lengths\n", src->hrec[i]->vals[0]);
+ ret |= 1;
+ }
+ if ( (kh_val(d_src,k_src).info[rec->type]>>4 & 0xf) != (kh_val(d_dst,k_dst).info[rec->type]>>4 & 0xf) )
+ {
+ fprintf(stderr,"Warning: trying to combine \"%s\" tag definitions of different types\n", src->hrec[i]->vals[0]);
+ ret |= 1;
+ }
+ }
+ }
+ }
+ if ( need_sync ) bcf_hdr_sync(dst);
+ return dst;
+}
+int bcf_translate(const bcf_hdr_t *dst_hdr, bcf_hdr_t *src_hdr, bcf1_t *line)
+{
+ int i;
+ if ( line->errcode )
+ {
+ fprintf(stderr,"[%s:%d %s] Unchecked error (%d), exiting.\n", __FILE__,__LINE__,__FUNCTION__,line->errcode);
+ exit(1);
+ }
+ if ( src_hdr->ntransl==-1 ) return 0; // no need to translate, all tags have the same id
+ if ( !src_hdr->ntransl ) // called for the first time, see what needs translating
+ {
+ int dict;
+ for (dict=0; dict<2; dict++) // BCF_DT_ID and BCF_DT_CTG
+ {
+ src_hdr->transl[dict] = (int*) malloc(src_hdr->n[dict]*sizeof(int));
+ for (i=0; i<src_hdr->n[dict]; i++)
+ {
+ if ( !src_hdr->id[dict][i].key ) // gap left after removed BCF header lines
+ {
+ src_hdr->transl[dict][i] = -1;
+ continue;
+ }
+ src_hdr->transl[dict][i] = bcf_hdr_id2int(dst_hdr,dict,src_hdr->id[dict][i].key);
+ if ( src_hdr->transl[dict][i]!=-1 && i!=src_hdr->transl[dict][i] ) src_hdr->ntransl++;
+ }
+ }
+ if ( !src_hdr->ntransl )
+ {
+ free(src_hdr->transl[0]); src_hdr->transl[0] = NULL;
+ free(src_hdr->transl[1]); src_hdr->transl[1] = NULL;
+ src_hdr->ntransl = -1;
+ }
+ if ( src_hdr->ntransl==-1 ) return 0;
+ }
+ bcf_unpack(line,BCF_UN_ALL);
+
+ // CHROM
+ if ( src_hdr->transl[BCF_DT_CTG][line->rid] >=0 ) line->rid = src_hdr->transl[BCF_DT_CTG][line->rid];
+
+ // FILTER
+ for (i=0; i<line->d.n_flt; i++)
+ {
+ int src_id = line->d.flt[i];
+ if ( src_hdr->transl[BCF_DT_ID][src_id] >=0 )
+ line->d.flt[i] = src_hdr->transl[BCF_DT_ID][src_id];
+ line->d.shared_dirty |= BCF1_DIRTY_FLT;
+ }
+
+ // INFO
+ for (i=0; i<line->n_info; i++)
+ {
+ int src_id = line->d.info[i].key;
+ int dst_id = src_hdr->transl[BCF_DT_ID][src_id];
+ if ( dst_id<0 ) continue;
+ int src_size = src_id>>7 ? ( src_id>>15 ? BCF_BT_INT32 : BCF_BT_INT16) : BCF_BT_INT8;
+ int dst_size = dst_id>>7 ? ( dst_id>>15 ? BCF_BT_INT32 : BCF_BT_INT16) : BCF_BT_INT8;
+ if ( src_size==dst_size ) // can overwrite
+ {
+ line->d.info[i].key = dst_id;
+ uint8_t *vptr = line->d.info[i].vptr - line->d.info[i].vptr_off;
+ if ( dst_size==BCF_BT_INT8 ) { vptr[1] = (uint8_t)dst_id; }
+ else if ( dst_size==BCF_BT_INT16 ) { *(uint16_t*)vptr = (uint16_t)dst_id; }
+ else { *(uint32_t*)vptr = (uint32_t)dst_id; }
+ }
+ else // must realloc
+ {
+ bcf_info_t *info = &line->d.info[i];
+ assert( !info->vptr_free );
+ kstring_t str = {0,0,0};
+ bcf_enc_int1(&str, dst_id);
+ bcf_enc_size(&str, info->len,info->type);
+ info->vptr_off = str.l;
+ kputsn((char*)info->vptr, info->vptr_len, &str);
+ info->vptr = (uint8_t*)str.s + info->vptr_off;
+ info->vptr_free = 1;
+ info->key = dst_id;
+ line->d.shared_dirty |= BCF1_DIRTY_INF;
+ }
+ }
+
+ // FORMAT
+ for (i=0; i<line->n_fmt; i++)
+ {
+ int src_id = line->d.fmt[i].id;
+ int dst_id = src_hdr->transl[BCF_DT_ID][src_id];
+ if ( dst_id<0 ) continue;
+ int src_size = src_id>>7 ? ( src_id>>15 ? BCF_BT_INT32 : BCF_BT_INT16) : BCF_BT_INT8;
+ int dst_size = dst_id>>7 ? ( dst_id>>15 ? BCF_BT_INT32 : BCF_BT_INT16) : BCF_BT_INT8;
+ if ( src_size==dst_size ) // can overwrite
+ {
+ line->d.fmt[i].id = dst_id;
+ uint8_t *p = line->d.fmt[i].p - line->d.fmt[i].p_off; // pointer to the vector size (4bits) and BT type (4bits)
+ if ( dst_size==BCF_BT_INT8 ) { p[1] = dst_id; }
+ else if ( dst_size==BCF_BT_INT16 ) { uint8_t *x = (uint8_t*) &dst_id; p[1] = x[0]; p[2] = x[1]; }
+ else { uint8_t *x = (uint8_t*) &dst_id; p[1] = x[0]; p[2] = x[1]; p[3] = x[2]; p[4] = x[3]; }
+ }
+ else // must realloc
+ {
+ bcf_fmt_t *fmt = &line->d.fmt[i];
+ assert( !fmt->p_free );
+ kstring_t str = {0,0,0};
+ bcf_enc_int1(&str, dst_id);
+ bcf_enc_size(&str, fmt->n, fmt->type);
+ fmt->p_off = str.l;
+ kputsn((char*)fmt->p, fmt->p_len, &str);
+ fmt->p = (uint8_t*)str.s + fmt->p_off;
+ fmt->p_free = 1;
+ fmt->id = dst_id;
+ line->d.indiv_dirty = 1;
+ }
+ }
+ return 0;
+}
+
+bcf_hdr_t *bcf_hdr_dup(const bcf_hdr_t *hdr)
+{
+ bcf_hdr_t *hout = bcf_hdr_init("r");
+ char *htxt = bcf_hdr_fmt_text(hdr, 1, NULL);
+ if (!hout) {
+ fprintf(stderr, "[E::%s] failed to allocate bcf header\n", __func__);
+ free(htxt);
+ return NULL;
+ }
+ bcf_hdr_parse(hout, htxt);
+ free(htxt);
+ return hout;
+}
+
+bcf_hdr_t *bcf_hdr_subset(const bcf_hdr_t *h0, int n, char *const* samples, int *imap)
+{
+ int hlen;
+ void *names_hash = khash_str2int_init();
+ char *htxt = bcf_hdr_fmt_text(h0, 1, &hlen);
+ kstring_t str;
+ bcf_hdr_t *h;
+ str.l = str.m = 0; str.s = 0;
+ h = bcf_hdr_init("w");
+ if (!h) {
+ fprintf(stderr, "[E::%s] failed to allocate bcf header\n", __func__);
+ free(htxt);
+ return NULL;
+ }
+ bcf_hdr_set_version(h,bcf_hdr_get_version(h0));
+ int j;
+ for (j=0; j<n; j++) imap[j] = -1;
+ if ( bcf_hdr_nsamples(h0) > 0) {
+ char *p;
+ int i = 0, end = n? 8 : 7;
+ while ((p = strstr(htxt, "#CHROM\t")) != 0)
+ if (p > htxt && *(p-1) == '\n') break;
+ while ((p = strchr(p, '\t')) != 0 && i < end) ++i, ++p;
+ if (i != end) {
+ free(h); free(str.s);
+ return 0; // malformated header
+ }
+ kputsn(htxt, p - htxt, &str);
+ for (i = 0; i < n; ++i) {
+ if ( khash_str2int_has_key(names_hash,samples[i]) )
+ {
+ fprintf(stderr,"[E::bcf_hdr_subset] Duplicate sample name \"%s\".\n", samples[i]);
+ free(str.s);
+ free(htxt);
+ khash_str2int_destroy(names_hash);
+ bcf_hdr_destroy(h);
+ return NULL;
+ }
+ imap[i] = bcf_hdr_id2int(h0, BCF_DT_SAMPLE, samples[i]);
+ if (imap[i] < 0) continue;
+ kputc('\t', &str);
+ kputs(samples[i], &str);
+ khash_str2int_inc(names_hash,samples[i]);
+ }
+ } else kputsn(htxt, hlen, &str);
+ while (str.l && (!str.s[str.l-1] || str.s[str.l-1]=='\n') ) str.l--; // kill trailing zeros and newlines
+ kputc('\n',&str);
+ bcf_hdr_parse(h, str.s);
+ free(str.s);
+ free(htxt);
+ khash_str2int_destroy(names_hash);
+ return h;
+}
+
+int bcf_hdr_set_samples(bcf_hdr_t *hdr, const char *samples, int is_file)
+{
+ if ( samples && !strcmp("-",samples) ) return 0; // keep all samples
+
+ hdr->nsamples_ori = bcf_hdr_nsamples(hdr);
+ if ( !samples ) { bcf_hdr_nsamples(hdr) = 0; return 0; } // exclude all samples
+
+ int i, narr = bit_array_size(bcf_hdr_nsamples(hdr));
+ hdr->keep_samples = (uint8_t*) calloc(narr,1);
+ if ( samples[0]=='^' )
+ for (i=0; i<bcf_hdr_nsamples(hdr); i++) bit_array_set(hdr->keep_samples,i);
+
+ int idx, n, ret = 0;
+ char **smpls = hts_readlist(samples[0]=='^'?samples+1:samples, is_file, &n);
+ if ( !smpls ) return -1;
+ for (i=0; i<n; i++)
+ {
+ idx = bcf_hdr_id2int(hdr,BCF_DT_SAMPLE,smpls[i]);
+ if ( idx<0 )
+ {
+ if ( !ret ) ret = i+1;
+ continue;
+ }
+ assert( idx<bcf_hdr_nsamples(hdr) );
+ if ( samples[0]=='^' )
+ bit_array_clear(hdr->keep_samples, idx);
+ else
+ bit_array_set(hdr->keep_samples, idx);
+ }
+ for (i=0; i<n; i++) free(smpls[i]);
+ free(smpls);
+
+ bcf_hdr_nsamples(hdr) = 0;
+ for (i=0; i<hdr->nsamples_ori; i++)
+ if ( bit_array_test(hdr->keep_samples,i) ) bcf_hdr_nsamples(hdr)++;
+ if ( !bcf_hdr_nsamples(hdr) ) { free(hdr->keep_samples); hdr->keep_samples=NULL; }
+ else
+ {
+ char **samples = (char**) malloc(sizeof(char*)*bcf_hdr_nsamples(hdr));
+ idx = 0;
+ for (i=0; i<hdr->nsamples_ori; i++)
+ if ( bit_array_test(hdr->keep_samples,i) ) samples[idx++] = strdup(hdr->samples[i]);
+ free(hdr->samples);
+ hdr->samples = samples;
+
+ // delete original samples from the dictionary
+ vdict_t *d = (vdict_t*)hdr->dict[BCF_DT_SAMPLE];
+ int k;
+ for (k = kh_begin(d); k != kh_end(d); ++k)
+ if (kh_exist(d, k)) free((char*)kh_key(d, k));
+ kh_destroy(vdict, d);
+
+ // add the subset back
+ hdr->dict[BCF_DT_SAMPLE] = d = kh_init(vdict);
+ for (i=0; i<bcf_hdr_nsamples(hdr); i++)
+ {
+ int ignore, k = kh_put(vdict, d, hdr->samples[i], &ignore);
+ kh_val(d, k) = bcf_idinfo_def;
+ kh_val(d, k).id = kh_size(d) - 1;
+ }
+ bcf_hdr_sync(hdr);
+ }
+
+ return ret;
+}
+
+int bcf_subset(const bcf_hdr_t *h, bcf1_t *v, int n, int *imap)
+{
+ kstring_t ind;
+ ind.s = 0; ind.l = ind.m = 0;
+ if (n) {
+ bcf_fmt_t *fmt;
+ int i, j;
+ fmt = (bcf_fmt_t*)alloca(v->n_fmt * sizeof(bcf_fmt_t));
+ uint8_t *ptr = (uint8_t*)v->indiv.s;
+ for (i = 0; i < v->n_fmt; ++i)
+ ptr = bcf_unpack_fmt_core1(ptr, v->n_sample, &fmt[i]);
+ for (i = 0; i < (int)v->n_fmt; ++i) {
+ bcf_fmt_t *f = &fmt[i];
+ bcf_enc_int1(&ind, f->id);
+ bcf_enc_size(&ind, f->n, f->type);
+ for (j = 0; j < n; ++j)
+ if (imap[j] >= 0) kputsn((char*)(f->p + imap[j] * f->size), f->size, &ind);
+ }
+ for (i = j = 0; j < n; ++j) if (imap[j] >= 0) ++i;
+ v->n_sample = i;
+ } else v->n_sample = 0;
+ if ( !v->n_sample ) v->n_fmt = 0;
+ free(v->indiv.s);
+ v->indiv = ind;
+ v->unpacked &= ~BCF_UN_FMT; // only BCF is ready for output, VCF will need to unpack again
+ return 0;
+}
+
+int bcf_is_snp(bcf1_t *v)
+{
+ int i;
+ bcf_unpack(v, BCF_UN_STR);
+ for (i = 0; i < v->n_allele; ++i)
+ {
+ if ( v->d.allele[i][1]==0 ) continue;
+
+ // mpileup's <X> allele, see also below. This is not completely satisfactory,
+ // a general library is here narrowly tailored to fit samtools.
+ if ( v->d.allele[i][0]=='<' && v->d.allele[i][1]=='X' && v->d.allele[i][2]=='>' ) continue;
+ if ( v->d.allele[i][0]=='<' && v->d.allele[i][1]=='*' && v->d.allele[i][2]=='>' ) continue;
+
+ break;
+ }
+ return i == v->n_allele;
+}
+
+static void bcf_set_variant_type(const char *ref, const char *alt, variant_t *var)
+{
+ // The most frequent case
+ if ( !ref[1] && !alt[1] )
+ {
+ if ( *alt == '.' || *ref==*alt ) { var->n = 0; var->type = VCF_REF; return; }
+ if ( *alt == 'X' ) { var->n = 0; var->type = VCF_REF; return; } // mpileup's X allele shouldn't be treated as variant
+ if ( *alt == '*' ) { var->n = 0; var->type = VCF_REF; return; }
+ var->n = 1; var->type = VCF_SNP; return;
+ }
+ if ( alt[0]=='<' )
+ {
+ if ( alt[1]=='X' && alt[2]=='>' ) { var->n = 0; var->type = VCF_REF; return; } // mpileup's X allele shouldn't be treated as variant
+ if ( alt[1]=='*' && alt[2]=='>' ) { var->n = 0; var->type = VCF_REF; return; }
+ var->type = VCF_OTHER;
+ return;
+ }
+
+ const char *r = ref, *a = alt;
+ while (*r && *a && toupper(*r)==toupper(*a) ) { r++; a++; } // unfortunately, matching REF,ALT case is not guaranteed
+
+ if ( *a && !*r )
+ {
+ while ( *a ) a++;
+ var->n = (a-alt)-(r-ref); var->type = VCF_INDEL; return;
+ }
+ else if ( *r && !*a )
+ {
+ while ( *r ) r++;
+ var->n = (a-alt)-(r-ref); var->type = VCF_INDEL; return;
+ }
+ else if ( !*r && !*a )
+ {
+ var->n = 0; var->type = VCF_REF; return;
+ }
+
+ const char *re = r, *ae = a;
+ while ( re[1] ) re++;
+ while ( ae[1] ) ae++;
+ while ( re>r && ae>a && toupper(*re)==toupper(*ae) ) { re--; ae--; }
+ if ( ae==a )
+ {
+ if ( re==r ) { var->n = 1; var->type = VCF_SNP; return; }
+ var->n = -(re-r);
+ if ( toupper(*re)==toupper(*ae) ) { var->type = VCF_INDEL; return; }
+ var->type = VCF_OTHER; return;
+ }
+ else if ( re==r )
+ {
+ var->n = ae-a;
+ if ( toupper(*re)==toupper(*ae) ) { var->type = VCF_INDEL; return; }
+ var->type = VCF_OTHER; return;
+ }
+
+ var->type = ( re-r == ae-a ) ? VCF_MNP : VCF_OTHER;
+ var->n = ( re-r > ae-a ) ? -(re-r+1) : ae-a+1;
+
+ // should do also complex events, SVs, etc...
+}
+
+static void bcf_set_variant_types(bcf1_t *b)
+{
+ if ( !(b->unpacked & BCF_UN_STR) ) bcf_unpack(b, BCF_UN_STR);
+ bcf_dec_t *d = &b->d;
+ if ( d->n_var < b->n_allele )
+ {
+ d->var = (variant_t *) realloc(d->var, sizeof(variant_t)*b->n_allele);
+ d->n_var = b->n_allele;
+ }
+ int i;
+ b->d.var_type = 0;
+ for (i=1; i<b->n_allele; i++)
+ {
+ bcf_set_variant_type(d->allele[0],d->allele[i], &d->var[i]);
+ b->d.var_type |= d->var[i].type;
+ //fprintf(stderr,"[set_variant_type] %d %s %s -> %d %d .. %d\n", b->pos+1,d->allele[0],d->allele[i],d->var[i].type,d->var[i].n, b->d.var_type);
+ }
+}
+
+int bcf_get_variant_types(bcf1_t *rec)
+{
+ if ( rec->d.var_type==-1 ) bcf_set_variant_types(rec);
+ return rec->d.var_type;
+}
+int bcf_get_variant_type(bcf1_t *rec, int ith_allele)
+{
+ if ( rec->d.var_type==-1 ) bcf_set_variant_types(rec);
+ return rec->d.var[ith_allele].type;
+}
+
+int bcf_update_info(const bcf_hdr_t *hdr, bcf1_t *line, const char *key, const void *values, int n, int type)
+{
+ // Is the field already present?
+ int i, inf_id = bcf_hdr_id2int(hdr,BCF_DT_ID,key);
+ if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,inf_id) ) return -1; // No such INFO field in the header
+ if ( !(line->unpacked & BCF_UN_INFO) ) bcf_unpack(line, BCF_UN_INFO);
+
+ for (i=0; i<line->n_info; i++)
+ if ( inf_id==line->d.info[i].key ) break;
+ bcf_info_t *inf = i==line->n_info ? NULL : &line->d.info[i];
+
+ if ( !n || (type==BCF_HT_STR && !values) )
+ {
+ if ( n==0 && !strcmp("END",key) )
+ line->rlen = line->n_allele ? strlen(line->d.allele[0]) : 0;
+ if ( inf )
+ {
+ // Mark the tag for removal, free existing memory if necessary
+ if ( inf->vptr_free )
+ {
+ free(inf->vptr - inf->vptr_off);
+ inf->vptr_free = 0;
+ }
+ line->d.shared_dirty |= BCF1_DIRTY_INF;
+ inf->vptr = NULL;
+ }
+ return 0;
+ }
+
+ // Encode the values and determine the size required to accommodate the values
+ kstring_t str = {0,0,0};
+ bcf_enc_int1(&str, inf_id);
+ if ( type==BCF_HT_INT )
+ bcf_enc_vint(&str, n, (int32_t*)values, -1);
+ else if ( type==BCF_HT_REAL )
+ bcf_enc_vfloat(&str, n, (float*)values);
+ else if ( type==BCF_HT_FLAG || type==BCF_HT_STR )
+ {
+ if ( values==NULL )
+ bcf_enc_size(&str, 0, BCF_BT_NULL);
+ else
+ bcf_enc_vchar(&str, strlen((char*)values), (char*)values);
+ }
+ else
+ {
+ fprintf(stderr, "[E::%s] the type %d not implemented yet\n", __func__, type);
+ abort();
+ }
+
+ // Is the INFO tag already present
+ if ( inf )
+ {
+ // Is it big enough to accommodate new block?
+ if ( str.l <= inf->vptr_len + inf->vptr_off )
+ {
+ if ( str.l != inf->vptr_len + inf->vptr_off ) line->d.shared_dirty |= BCF1_DIRTY_INF;
+ uint8_t *ptr = inf->vptr - inf->vptr_off;
+ memcpy(ptr, str.s, str.l);
+ free(str.s);
+ int vptr_free = inf->vptr_free;
+ bcf_unpack_info_core1(ptr, inf);
+ inf->vptr_free = vptr_free;
+ }
+ else
+ {
+ assert( !inf->vptr_free ); // fix the caller or improve here: this has been modified before
+ bcf_unpack_info_core1((uint8_t*)str.s, inf);
+ inf->vptr_free = 1;
+ line->d.shared_dirty |= BCF1_DIRTY_INF;
+ }
+ }
+ else
+ {
+ // The tag is not present, create new one
+ line->n_info++;
+ hts_expand0(bcf_info_t, line->n_info, line->d.m_info , line->d.info);
+ inf = &line->d.info[line->n_info-1];
+ bcf_unpack_info_core1((uint8_t*)str.s, inf);
+ inf->vptr_free = 1;
+ line->d.shared_dirty |= BCF1_DIRTY_INF;
+ }
+ line->unpacked |= BCF_UN_INFO;
+
+ if ( n==1 && !strcmp("END",key) ) line->rlen = ((int32_t*)values)[0] - line->pos;
+ return 0;
+}
+
+int bcf_update_format_string(const bcf_hdr_t *hdr, bcf1_t *line, const char *key, const char **values, int n)
+{
+ if ( !n )
+ return bcf_update_format(hdr,line,key,NULL,0,BCF_HT_STR);
+
+ int i, max_len = 0;
+ for (i=0; i<n; i++)
+ {
+ int len = strlen(values[i]);
+ if ( len > max_len ) max_len = len;
+ }
+ char *out = (char*) malloc(max_len*n);
+ if ( !out ) return -2;
+ for (i=0; i<n; i++)
+ {
+ char *dst = out+i*max_len;
+ const char *src = values[i];
+ int j = 0;
+ while ( src[j] ) { dst[j] = src[j]; j++; }
+ for (; j<max_len; j++) dst[j] = 0;
+ }
+ int ret = bcf_update_format(hdr,line,key,out,max_len*n,BCF_HT_STR);
+ free(out);
+ return ret;
+}
+
+int bcf_update_format(const bcf_hdr_t *hdr, bcf1_t *line, const char *key, const void *values, int n, int type)
+{
+ // Is the field already present?
+ int i, fmt_id = bcf_hdr_id2int(hdr,BCF_DT_ID,key);
+ if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,fmt_id) )
+ {
+ if ( !n ) return 0;
+ return -1; // the key not present in the header
+ }
+
+ if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT);
+
+ for (i=0; i<line->n_fmt; i++)
+ if ( line->d.fmt[i].id==fmt_id ) break;
+ bcf_fmt_t *fmt = i==line->n_fmt ? NULL : &line->d.fmt[i];
+
+ if ( !n )
+ {
+ if ( fmt )
+ {
+ // Mark the tag for removal, free existing memory if necessary
+ if ( fmt->p_free )
+ {
+ free(fmt->p - fmt->p_off);
+ fmt->p_free = 0;
+ }
+ line->d.indiv_dirty = 1;
+ fmt->p = NULL;
+ }
+ return 0;
+ }
+
+ line->n_sample = bcf_hdr_nsamples(hdr);
+ int nps = n / line->n_sample; // number of values per sample
+ assert( nps && nps*line->n_sample==n ); // must be divisible by n_sample
+
+ // Encode the values and determine the size required to accommodate the values
+ kstring_t str = {0,0,0};
+ bcf_enc_int1(&str, fmt_id);
+ if ( type==BCF_HT_INT )
+ bcf_enc_vint(&str, n, (int32_t*)values, nps);
+ else if ( type==BCF_HT_REAL )
+ {
+ bcf_enc_size(&str, nps, BCF_BT_FLOAT);
+ kputsn((char*)values, nps*line->n_sample*sizeof(float), &str);
+ }
+ else if ( type==BCF_HT_STR )
+ {
+ bcf_enc_size(&str, nps, BCF_BT_CHAR);
+ kputsn((char*)values, nps*line->n_sample, &str);
+ }
+ else
+ {
+ fprintf(stderr, "[E::%s] the type %d not implemented yet\n", __func__, type);
+ abort();
+ }
+
+ if ( !fmt )
+ {
+ // Not present, new format field
+ line->n_fmt++;
+ hts_expand0(bcf_fmt_t, line->n_fmt, line->d.m_fmt, line->d.fmt);
+
+ // Special case: VCF specification requires that GT is always first
+ if ( line->n_fmt > 1 && key[0]=='G' && key[1]=='T' && !key[2] )
+ {
+ for (i=line->n_fmt-1; i>0; i--)
+ line->d.fmt[i] = line->d.fmt[i-1];
+ fmt = &line->d.fmt[0];
+ }
+ else
+ fmt = &line->d.fmt[line->n_fmt-1];
+ bcf_unpack_fmt_core1((uint8_t*)str.s, line->n_sample, fmt);
+ line->d.indiv_dirty = 1;
+ fmt->p_free = 1;
+ }
+ else
+ {
+ // The tag is already present, check if it is big enough to accomodate the new block
+ if ( str.l <= fmt->p_len + fmt->p_off )
+ {
+ // good, the block is big enough
+ if ( str.l != fmt->p_len + fmt->p_off ) line->d.indiv_dirty = 1;
+ uint8_t *ptr = fmt->p - fmt->p_off;
+ memcpy(ptr, str.s, str.l);
+ free(str.s);
+ int p_free = fmt->p_free;
+ bcf_unpack_fmt_core1(ptr, line->n_sample, fmt);
+ fmt->p_free = p_free;
+ }
+ else
+ {
+ assert( !fmt->p_free ); // fix the caller or improve here: this has been modified before
+ bcf_unpack_fmt_core1((uint8_t*)str.s, line->n_sample, fmt);
+ fmt->p_free = 1;
+ line->d.indiv_dirty = 1;
+ }
+ }
+ line->unpacked |= BCF_UN_FMT;
+ return 0;
+}
+
+
+int bcf_update_filter(const bcf_hdr_t *hdr, bcf1_t *line, int *flt_ids, int n)
+{
+ if ( !(line->unpacked & BCF_UN_FLT) ) bcf_unpack(line, BCF_UN_FLT);
+ line->d.shared_dirty |= BCF1_DIRTY_FLT;
+ line->d.n_flt = n;
+ if ( !n ) return 0;
+ hts_expand(int, line->d.n_flt, line->d.m_flt, line->d.flt);
+ int i;
+ for (i=0; i<n; i++)
+ line->d.flt[i] = flt_ids[i];
+ return 0;
+}
+
+int bcf_add_filter(const bcf_hdr_t *hdr, bcf1_t *line, int flt_id)
+{
+ if ( !(line->unpacked & BCF_UN_FLT) ) bcf_unpack(line, BCF_UN_FLT);
+ int i;
+ for (i=0; i<line->d.n_flt; i++)
+ if ( flt_id==line->d.flt[i] ) break;
+ if ( i<line->d.n_flt ) return 0; // this filter is already set
+ line->d.shared_dirty |= BCF1_DIRTY_FLT;
+ if ( flt_id==0 ) // set to PASS
+ line->d.n_flt = 1;
+ else if ( line->d.n_flt==1 && line->d.flt[0]==0 )
+ line->d.n_flt = 1;
+ else
+ line->d.n_flt++;
+ hts_expand(int, line->d.n_flt, line->d.m_flt, line->d.flt);
+ line->d.flt[line->d.n_flt-1] = flt_id;
+ return 1;
+}
+int bcf_remove_filter(const bcf_hdr_t *hdr, bcf1_t *line, int flt_id, int pass)
+{
+ if ( !(line->unpacked & BCF_UN_FLT) ) bcf_unpack(line, BCF_UN_FLT);
+ int i;
+ for (i=0; i<line->d.n_flt; i++)
+ if ( flt_id==line->d.flt[i] ) break;
+ if ( i==line->d.n_flt ) return 0; // the filter is not present
+ line->d.shared_dirty |= BCF1_DIRTY_FLT;
+ if ( i!=line->d.n_flt-1 ) memmove(line->d.flt+i,line->d.flt+i+1,(line->d.n_flt-i-1)*sizeof(*line->d.flt));
+ line->d.n_flt--;
+ if ( !line->d.n_flt && pass ) bcf_add_filter(hdr,line,0);
+ return 0;
+}
+
+int bcf_has_filter(const bcf_hdr_t *hdr, bcf1_t *line, char *filter)
+{
+ if ( filter[0]=='.' && !filter[1] ) filter = "PASS";
+ int id = bcf_hdr_id2int(hdr, BCF_DT_ID, filter);
+ if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_FLT,id) ) return -1; // not defined in the header
+
+ if ( !(line->unpacked & BCF_UN_FLT) ) bcf_unpack(line, BCF_UN_FLT);
+ if ( id==0 && !line->d.n_flt) return 1; // PASS
+
+ int i;
+ for (i=0; i<line->d.n_flt; i++)
+ if ( line->d.flt[i]==id ) return 1;
+ return 0;
+}
+
+static inline int _bcf1_sync_alleles(const bcf_hdr_t *hdr, bcf1_t *line, int nals)
+{
+ line->d.shared_dirty |= BCF1_DIRTY_ALS;
+
+ line->n_allele = nals;
+ hts_expand(char*, line->n_allele, line->d.m_allele, line->d.allele);
+
+ char *als = line->d.als;
+ int n = 0;
+ while (n<nals)
+ {
+ line->d.allele[n] = als;
+ while ( *als ) als++;
+ als++;
+ n++;
+ }
+
+ // Update REF length
+ bcf_info_t *end_info = bcf_get_info(hdr,line,"END");
+ line->rlen = end_info ? end_info->v1.i : strlen(line->d.allele[0]);
+
+ return 0;
+}
+int bcf_update_alleles(const bcf_hdr_t *hdr, bcf1_t *line, const char **alleles, int nals)
+{
+ kstring_t tmp = {0,0,0};
+ char *free_old = NULL;
+
+ // If the supplied alleles are not pointers to line->d.als, the existing block can be reused.
+ int i;
+ for (i=0; i<nals; i++)
+ if ( alleles[i]>=line->d.als && alleles[i]<line->d.als+line->d.m_als ) break;
+ if ( i==nals )
+ {
+ // all alleles point elsewhere, reuse the existing block
+ tmp.l = 0; tmp.s = line->d.als; tmp.m = line->d.m_als;
+ }
+ else
+ free_old = line->d.als;
+
+ for (i=0; i<nals; i++)
+ {
+ kputs(alleles[i], &tmp);
+ kputc(0, &tmp);
+ }
+ line->d.als = tmp.s; line->d.m_als = tmp.m;
+ free(free_old);
+ return _bcf1_sync_alleles(hdr,line,nals);
+}
+
+int bcf_update_alleles_str(const bcf_hdr_t *hdr, bcf1_t *line, const char *alleles_string)
+{
+ kstring_t tmp;
+ tmp.l = 0; tmp.s = line->d.als; tmp.m = line->d.m_als;
+ kputs(alleles_string, &tmp);
+ line->d.als = tmp.s; line->d.m_als = tmp.m;
+
+ int nals = 1;
+ char *t = line->d.als;
+ while (*t)
+ {
+ if ( *t==',' ) { *t = 0; nals++; }
+ t++;
+ }
+ return _bcf1_sync_alleles(hdr, line, nals);
+}
+
+int bcf_update_id(const bcf_hdr_t *hdr, bcf1_t *line, const char *id)
+{
+ kstring_t tmp;
+ tmp.l = 0; tmp.s = line->d.id; tmp.m = line->d.m_id;
+ if ( id )
+ kputs(id, &tmp);
+ else
+ kputs(".", &tmp);
+ line->d.id = tmp.s; line->d.m_id = tmp.m;
+ line->d.shared_dirty |= BCF1_DIRTY_ID;
+ return 0;
+}
+
+int bcf_add_id(const bcf_hdr_t *hdr, bcf1_t *line, const char *id)
+{
+ if ( !id ) return 0;
+
+ kstring_t tmp;
+ tmp.l = 0; tmp.s = line->d.id; tmp.m = line->d.m_id;
+
+ int len = strlen(id);
+ char *dst = line->d.id;
+ while ( *dst && (dst=strstr(dst,id)) )
+ {
+ if ( dst[len]!=0 && dst[len]!=';' ) dst++; // a prefix, not a match
+ else if ( dst==line->d.id || dst[-1]==';' ) return 0; // already present
+ dst++; // a suffix, not a match
+ }
+ if ( line->d.id && (line->d.id[0]!='.' || line->d.id[1]) )
+ {
+ tmp.l = strlen(line->d.id);
+ kputc(';',&tmp);
+ }
+ kputs(id,&tmp);
+
+ line->d.id = tmp.s; line->d.m_id = tmp.m;
+ line->d.shared_dirty |= BCF1_DIRTY_ID;
+ return 0;
+
+}
+
+bcf_fmt_t *bcf_get_fmt(const bcf_hdr_t *hdr, bcf1_t *line, const char *key)
+{
+ int id = bcf_hdr_id2int(hdr, BCF_DT_ID, key);
+ if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,id) ) return NULL; // no such FMT field in the header
+ return bcf_get_fmt_id(line, id);
+}
+
+bcf_info_t *bcf_get_info(const bcf_hdr_t *hdr, bcf1_t *line, const char *key)
+{
+ int id = bcf_hdr_id2int(hdr, BCF_DT_ID, key);
+ if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,id) ) return NULL; // no such INFO field in the header
+ return bcf_get_info_id(line, id);
+}
+
+bcf_fmt_t *bcf_get_fmt_id(bcf1_t *line, const int id)
+{
+ int i;
+ if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT);
+ for (i=0; i<line->n_fmt; i++)
+ {
+ if ( line->d.fmt[i].id==id ) return &line->d.fmt[i];
+ }
+ return NULL;
+}
+
+bcf_info_t *bcf_get_info_id(bcf1_t *line, const int id)
+{
+ int i;
+ if ( !(line->unpacked & BCF_UN_INFO) ) bcf_unpack(line, BCF_UN_INFO);
+ for (i=0; i<line->n_info; i++)
+ {
+ if ( line->d.info[i].key==id ) return &line->d.info[i];
+ }
+ return NULL;
+}
+
+
+int bcf_get_info_values(const bcf_hdr_t *hdr, bcf1_t *line, const char *tag, void **dst, int *ndst, int type)
+{
+ int i,j, tag_id = bcf_hdr_id2int(hdr, BCF_DT_ID, tag);
+ if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,tag_id) ) return -1; // no such INFO field in the header
+ if ( bcf_hdr_id2type(hdr,BCF_HL_INFO,tag_id)!=type ) return -2; // expected different type
+
+ if ( !(line->unpacked & BCF_UN_INFO) ) bcf_unpack(line, BCF_UN_INFO);
+
+ for (i=0; i<line->n_info; i++)
+ if ( line->d.info[i].key==tag_id ) break;
+ if ( i==line->n_info ) return ( type==BCF_HT_FLAG ) ? 0 : -3; // the tag is not present in this record
+ if ( type==BCF_HT_FLAG ) return 1;
+
+ bcf_info_t *info = &line->d.info[i];
+ if ( !info->vptr ) return -3; // the tag was marked for removal
+ if ( type==BCF_HT_STR )
+ {
+ if ( *ndst < info->len+1 )
+ {
+ *ndst = info->len + 1;
+ *dst = realloc(*dst, *ndst);
+ }
+ memcpy(*dst,info->vptr,info->len);
+ ((uint8_t*)*dst)[info->len] = 0;
+ return info->len;
+ }
+
+ // Make sure the buffer is big enough
+ int size1 = type==BCF_HT_INT ? sizeof(int32_t) : sizeof(float);
+ if ( *ndst < info->len )
+ {
+ *ndst = info->len;
+ *dst = realloc(*dst, *ndst * size1);
+ }
+
+ if ( info->len == 1 )
+ {
+ if ( info->type==BCF_BT_FLOAT ) *((float*)*dst) = info->v1.f;
+ else
+ {
+ #define BRANCH(type_t, missing) { \
+ if ( info->v1.i==missing ) *((int32_t*)*dst) = bcf_int32_missing; \
+ else *((int32_t*)*dst) = info->v1.i; \
+ }
+ switch (info->type)
+ {
+ case BCF_BT_INT8: BRANCH(int8_t, bcf_int8_missing ); break;
+ case BCF_BT_INT16: BRANCH(int16_t, bcf_int16_missing); break;
+ case BCF_BT_INT32: BRANCH(int32_t, bcf_int32_missing); break;
+ }
+ #undef BRANCH
+ }
+ return 1;
+ }
+
+ #define BRANCH(type_t, is_missing, is_vector_end, set_missing, out_type_t) { \
+ out_type_t *tmp = (out_type_t *) *dst; \
+ type_t *p = (type_t *) info->vptr; \
+ for (j=0; j<info->len; j++) \
+ { \
+ if ( is_vector_end ) return j; \
+ if ( is_missing ) set_missing; \
+ else *tmp = p[j]; \
+ tmp++; \
+ } \
+ return j; \
+ }
+ switch (info->type) {
+ case BCF_BT_INT8: BRANCH(int8_t, p[j]==bcf_int8_missing, p[j]==bcf_int8_vector_end, *tmp=bcf_int32_missing, int32_t); break;
+ case BCF_BT_INT16: BRANCH(int16_t, p[j]==bcf_int16_missing, p[j]==bcf_int16_vector_end, *tmp=bcf_int32_missing, int32_t); break;
+ case BCF_BT_INT32: BRANCH(int32_t, p[j]==bcf_int32_missing, p[j]==bcf_int32_vector_end, *tmp=bcf_int32_missing, int32_t); break;
+ case BCF_BT_FLOAT: BRANCH(float, bcf_float_is_missing(p[j]), bcf_float_is_vector_end(p[j]), bcf_float_set_missing(*tmp), float); break;
+ default: fprintf(stderr,"TODO: %s:%d .. info->type=%d\n", __FILE__,__LINE__, info->type); exit(1);
+ }
+ #undef BRANCH
+ return -4; // this can never happen
+}
+
+int bcf_get_format_string(const bcf_hdr_t *hdr, bcf1_t *line, const char *tag, char ***dst, int *ndst)
+{
+ int i,tag_id = bcf_hdr_id2int(hdr, BCF_DT_ID, tag);
+ if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,tag_id) ) return -1; // no such FORMAT field in the header
+ if ( bcf_hdr_id2type(hdr,BCF_HL_FMT,tag_id)!=BCF_HT_STR ) return -2; // expected different type
+
+ if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT);
+
+ for (i=0; i<line->n_fmt; i++)
+ if ( line->d.fmt[i].id==tag_id ) break;
+ if ( i==line->n_fmt ) return -3; // the tag is not present in this record
+ bcf_fmt_t *fmt = &line->d.fmt[i];
+ if ( !fmt->p ) return -3; // the tag was marked for removal
+
+ int nsmpl = bcf_hdr_nsamples(hdr);
+ if ( !*dst )
+ {
+ *dst = (char**) malloc(sizeof(char*)*nsmpl);
+ if ( !*dst ) return -4; // could not alloc
+ (*dst)[0] = NULL;
+ }
+ int n = (fmt->n+1)*nsmpl;
+ if ( *ndst < n )
+ {
+ (*dst)[0] = realloc((*dst)[0], n);
+ if ( !(*dst)[0] ) return -4; // could not alloc
+ *ndst = n;
+ }
+ for (i=0; i<nsmpl; i++)
+ {
+ uint8_t *src = fmt->p + i*fmt->n;
+ uint8_t *tmp = (uint8_t*)(*dst)[0] + i*(fmt->n+1);
+ memcpy(tmp,src,fmt->n);
+ tmp[fmt->n] = 0;
+ (*dst)[i] = (char*) tmp;
+ }
+ return n;
+}
+
+int bcf_get_format_values(const bcf_hdr_t *hdr, bcf1_t *line, const char *tag, void **dst, int *ndst, int type)
+{
+ int i,j, tag_id = bcf_hdr_id2int(hdr, BCF_DT_ID, tag);
+ if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,tag_id) ) return -1; // no such FORMAT field in the header
+ if ( tag[0]=='G' && tag[1]=='T' && tag[2]==0 )
+ {
+ // Ugly: GT field is considered to be a string by the VCF header but BCF represents it as INT.
+ if ( bcf_hdr_id2type(hdr,BCF_HL_FMT,tag_id)!=BCF_HT_STR ) return -2;
+ }
+ else if ( bcf_hdr_id2type(hdr,BCF_HL_FMT,tag_id)!=type ) return -2; // expected different type
+
+ if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT);
+
+ for (i=0; i<line->n_fmt; i++)
+ if ( line->d.fmt[i].id==tag_id ) break;
+ if ( i==line->n_fmt ) return -3; // the tag is not present in this record
+ bcf_fmt_t *fmt = &line->d.fmt[i];
+ if ( !fmt->p ) return -3; // the tag was marked for removal
+
+ if ( type==BCF_HT_STR )
+ {
+ int n = fmt->n*bcf_hdr_nsamples(hdr);
+ if ( *ndst < n )
+ {
+ *dst = realloc(*dst, n);
+ if ( !*dst ) return -4; // could not alloc
+ *ndst = n;
+ }
+ memcpy(*dst,fmt->p,n);
+ return n;
+ }
+
+ // Make sure the buffer is big enough
+ int nsmpl = bcf_hdr_nsamples(hdr);
+ int size1 = type==BCF_HT_INT ? sizeof(int32_t) : sizeof(float);
+ if ( *ndst < fmt->n*nsmpl )
+ {
+ *ndst = fmt->n*nsmpl;
+ *dst = realloc(*dst, *ndst*size1);
+ if ( !dst ) return -4; // could not alloc
+ }
+
+ #define BRANCH(type_t, is_missing, is_vector_end, set_missing, set_vector_end, out_type_t) { \
+ out_type_t *tmp = (out_type_t *) *dst; \
+ type_t *p = (type_t*) fmt->p; \
+ for (i=0; i<nsmpl; i++) \
+ { \
+ for (j=0; j<fmt->n; j++) \
+ { \
+ if ( is_missing ) set_missing; \
+ else if ( is_vector_end ) { set_vector_end; break; } \
+ else *tmp = p[j]; \
+ tmp++; \
+ } \
+ for (; j<fmt->n; j++) { set_vector_end; tmp++; } \
+ p = (type_t *)((char *)p + fmt->size); \
+ } \
+ }
+ switch (fmt->type) {
+ case BCF_BT_INT8: BRANCH(int8_t, p[j]==bcf_int8_missing, p[j]==bcf_int8_vector_end, *tmp=bcf_int32_missing, *tmp=bcf_int32_vector_end, int32_t); break;
+ case BCF_BT_INT16: BRANCH(int16_t, p[j]==bcf_int16_missing, p[j]==bcf_int16_vector_end, *tmp=bcf_int32_missing, *tmp=bcf_int32_vector_end, int32_t); break;
+ case BCF_BT_INT32: BRANCH(int32_t, p[j]==bcf_int32_missing, p[j]==bcf_int32_vector_end, *tmp=bcf_int32_missing, *tmp=bcf_int32_vector_end, int32_t); break;
+ case BCF_BT_FLOAT: BRANCH(float, bcf_float_is_missing(p[j]), bcf_float_is_vector_end(p[j]), bcf_float_set_missing(*tmp), bcf_float_set_vector_end(*tmp), float); break;
+ default: fprintf(stderr,"TODO: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt->type); exit(1);
+ }
+ #undef BRANCH
+ return nsmpl*fmt->n;
+}
+
--- /dev/null
+/* vcf_sweep.c -- forward/reverse sweep API.
+
+ Copyright (C) 2013 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include "htslib/vcf_sweep.h"
+#include "htslib/bgzf.h"
+
+#define SW_FWD 0
+#define SW_BWD 1
+
+struct _bcf_sweep_t
+{
+ htsFile *file;
+ bcf_hdr_t *hdr;
+ BGZF *fp;
+
+ int direction; // to tell if the direction has changed
+ int block_size; // the size of uncompressed data to hold in memory
+ bcf1_t *rec; // bcf buffer
+ int nrec, mrec; // number of used records; total size of the buffer
+ int lrid, lpos, lnals, lals_len, mlals; // to check uniqueness of a record
+ char *lals;
+
+ uint64_t *idx; // uncompressed offsets of VCF/BCF records
+ int iidx, nidx, midx; // i: current offset; n: used; m: allocated
+ int idx_done; // the index is built during the first pass
+};
+
+BGZF *hts_get_bgzfp(htsFile *fp);
+int hts_useek(htsFile *file, long uoffset, int where);
+long hts_utell(htsFile *file);
+
+static inline int sw_rec_equal(bcf_sweep_t *sw, bcf1_t *rec)
+{
+ if ( sw->lrid!=rec->rid ) return 0;
+ if ( sw->lpos!=rec->pos ) return 0;
+ if ( sw->lnals!=rec->n_allele ) return 0;
+
+ char *t = rec->d.allele[sw->lnals-1];
+ int len = t - rec->d.allele[0] + 1;
+ while ( *t ) { t++; len++; }
+ if ( sw->lals_len!=len ) return 0;
+ if ( memcmp(sw->lals,rec->d.allele[0],len) ) return 0;
+ return 1;
+}
+
+static void sw_rec_save(bcf_sweep_t *sw, bcf1_t *rec)
+{
+ sw->lrid = rec->rid;
+ sw->lpos = rec->pos;
+ sw->lnals = rec->n_allele;
+
+ char *t = rec->d.allele[sw->lnals-1];
+ int len = t - rec->d.allele[0] + 1;
+ while ( *t ) { t++; len++; }
+ sw->lals_len = len;
+ hts_expand(char, len, sw->mlals, sw->lals);
+ memcpy(sw->lals, rec->d.allele[0], len);
+}
+
+static void sw_fill_buffer(bcf_sweep_t *sw)
+{
+ if ( !sw->iidx ) return;
+ sw->iidx--;
+
+ int ret = hts_useek(sw->file, sw->idx[sw->iidx], 0);
+ assert( ret==0 );
+
+ sw->nrec = 0;
+ bcf1_t *rec = &sw->rec[sw->nrec];
+ while ( (ret=bcf_read1(sw->file, sw->hdr, rec))==0 )
+ {
+ bcf_unpack(rec, BCF_UN_STR);
+
+ // if not in the last block, stop at the saved record
+ if ( sw->iidx+1 < sw->nidx && sw_rec_equal(sw,rec) ) break;
+
+ sw->nrec++;
+ hts_expand0(bcf1_t, sw->nrec+1, sw->mrec, sw->rec);
+ rec = &sw->rec[sw->nrec];
+ }
+ sw_rec_save(sw, &sw->rec[0]);
+}
+
+bcf_sweep_t *bcf_sweep_init(const char *fname)
+{
+ bcf_sweep_t *sw = (bcf_sweep_t*) calloc(1,sizeof(bcf_sweep_t));
+ sw->file = hts_open(fname, "r");
+ sw->fp = hts_get_bgzfp(sw->file);
+ bgzf_index_build_init(sw->fp);
+ sw->hdr = bcf_hdr_read(sw->file);
+ sw->mrec = 1;
+ sw->rec = (bcf1_t*) calloc(sw->mrec,(sizeof(bcf1_t)));
+ sw->block_size = 1024*1024*3;
+ sw->direction = SW_FWD;
+ return sw;
+}
+
+void bcf_sweep_destroy(bcf_sweep_t *sw)
+{
+ int i;
+ for (i=0; i<sw->mrec; i++) bcf_empty1(&sw->rec[i]);
+ free(sw->idx);
+ free(sw->rec);
+ free(sw->lals);
+ bcf_hdr_destroy(sw->hdr);
+ hts_close(sw->file);
+ free(sw);
+}
+
+static void sw_seek(bcf_sweep_t *sw, int direction)
+{
+ sw->direction = direction;
+ if ( direction==SW_FWD )
+ hts_useek(sw->file, sw->idx[0], 0);
+ else
+ {
+ sw->iidx = sw->nidx;
+ sw->nrec = 0;
+ }
+}
+
+bcf1_t *bcf_sweep_fwd(bcf_sweep_t *sw)
+{
+ if ( sw->direction==SW_BWD ) sw_seek(sw, SW_FWD);
+
+ long pos = hts_utell(sw->file);
+
+ bcf1_t *rec = &sw->rec[0];
+ int ret = bcf_read1(sw->file, sw->hdr, rec);
+
+ if ( ret!=0 ) // last record, get ready for sweeping backwards
+ {
+ sw->idx_done = 1;
+ sw->fp->idx_build_otf = 0;
+ sw_seek(sw, SW_BWD);
+ return NULL;
+ }
+
+ if ( !sw->idx_done )
+ {
+ if ( !sw->nidx || pos - sw->idx[sw->nidx-1] > sw->block_size )
+ {
+ sw->nidx++;
+ hts_expand(uint64_t, sw->nidx, sw->midx, sw->idx);
+ sw->idx[sw->nidx-1] = pos;
+ }
+ }
+ return rec;
+}
+
+bcf1_t *bcf_sweep_bwd(bcf_sweep_t *sw)
+{
+ if ( sw->direction==SW_FWD ) sw_seek(sw, SW_BWD);
+ if ( !sw->nrec ) sw_fill_buffer(sw);
+ if ( !sw->nrec ) return NULL;
+ return &sw->rec[ --sw->nrec ];
+}
+
+bcf_hdr_t *bcf_sweep_hdr(bcf_sweep_t *sw) { return sw->hdr; }
+
--- /dev/null
+/* vcfutils.c -- allele-related utility functions.
+
+ Copyright (C) 2012-2015 Genome Research Ltd.
+
+ Author: Petr Danecek <pd3@sanger.ac.uk>
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in
+all copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL
+THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING
+FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER
+DEALINGS IN THE SOFTWARE. */
+
+#include <config.h>
+
+#include "htslib/vcfutils.h"
+#include "htslib/kbitset.h"
+
+int bcf_calc_ac(const bcf_hdr_t *header, bcf1_t *line, int *ac, int which)
+{
+ int i;
+ for (i=0; i<line->n_allele; i++) ac[i]=0;
+
+ // Use INFO/AC,AN field only when asked
+ if ( which&BCF_UN_INFO )
+ {
+ bcf_unpack(line, BCF_UN_INFO);
+ int an_id = bcf_hdr_id2int(header, BCF_DT_ID, "AN");
+ int ac_id = bcf_hdr_id2int(header, BCF_DT_ID, "AC");
+ int i, an=-1, ac_len=0, ac_type=0;
+ uint8_t *ac_ptr=NULL;
+ if ( an_id>=0 && ac_id>=0 )
+ {
+ for (i=0; i<line->n_info; i++)
+ {
+ bcf_info_t *z = &line->d.info[i];
+ if ( z->key == an_id ) an = z->v1.i;
+ else if ( z->key == ac_id ) { ac_ptr = z->vptr; ac_len = z->len; ac_type = z->type; }
+ }
+ }
+ if ( an>=0 && ac_ptr )
+ {
+ int nac = 0;
+ #define BRANCH_INT(type_t) { \
+ type_t *p = (type_t *) ac_ptr; \
+ for (i=0; i<ac_len; i++) \
+ { \
+ ac[i+1] = p[i]; \
+ nac += p[i]; \
+ } \
+ }
+ switch (ac_type) {
+ case BCF_BT_INT8: BRANCH_INT(int8_t); break;
+ case BCF_BT_INT16: BRANCH_INT(int16_t); break;
+ case BCF_BT_INT32: BRANCH_INT(int32_t); break;
+ default: fprintf(stderr, "[E::%s] todo: %d at %s:%d\n", __func__, ac_type, header->id[BCF_DT_CTG][line->rid].key, line->pos+1); exit(1); break;
+ }
+ #undef BRANCH_INT
+ if ( an<nac )
+ {
+ fprintf(stderr,"[E::%s] Incorrect AN/AC counts at %s:%d\n", __func__,header->id[BCF_DT_CTG][line->rid].key, line->pos+1);
+ exit(1);
+ }
+ ac[0] = an - nac;
+ return 1;
+ }
+ }
+
+ // Split genotype fields only when asked
+ if ( which&BCF_UN_FMT )
+ {
+ int i, gt_id = bcf_hdr_id2int(header,BCF_DT_ID,"GT");
+ if ( gt_id<0 ) return 0;
+ bcf_unpack(line, BCF_UN_FMT);
+ bcf_fmt_t *fmt_gt = NULL;
+ for (i=0; i<(int)line->n_fmt; i++)
+ if ( line->d.fmt[i].id==gt_id ) { fmt_gt = &line->d.fmt[i]; break; }
+ if ( !fmt_gt ) return 0;
+ #define BRANCH_INT(type_t,vector_end) { \
+ for (i=0; i<line->n_sample; i++) \
+ { \
+ type_t *p = (type_t*) (fmt_gt->p + i*fmt_gt->size); \
+ int ial; \
+ for (ial=0; ial<fmt_gt->n; ial++) \
+ { \
+ if ( p[ial]==vector_end ) break; /* smaller ploidy */ \
+ if ( bcf_gt_is_missing(p[ial]) ) continue; /* missing allele */ \
+ if ( p[ial]>>1 > line->n_allele ) \
+ { \
+ fprintf(stderr,"[E::%s] Incorrect allele (\"%d\") in %s at %s:%d\n", __func__,(p[ial]>>1)-1, header->samples[i],header->id[BCF_DT_CTG][line->rid].key, line->pos+1); \
+ exit(1); \
+ } \
+ ac[(p[ial]>>1)-1]++; \
+ } \
+ } \
+ }
+ switch (fmt_gt->type) {
+ case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_vector_end); break;
+ case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_vector_end); break;
+ case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_vector_end); break;
+ default: fprintf(stderr, "[E::%s] todo: %d at %s:%d\n", __func__, fmt_gt->type, header->id[BCF_DT_CTG][line->rid].key, line->pos+1); exit(1); break;
+ }
+ #undef BRANCH_INT
+ return 1;
+ }
+ return 0;
+}
+
+int bcf_gt_type(bcf_fmt_t *fmt_ptr, int isample, int *_ial, int *_jal)
+{
+ int i, nals = 0, has_ref = 0, has_alt = 0, ial = 0, jal = 0;
+ #define BRANCH_INT(type_t,vector_end) { \
+ type_t *p = (type_t*) (fmt_ptr->p + isample*fmt_ptr->size); \
+ for (i=0; i<fmt_ptr->n; i++) \
+ { \
+ if ( p[i] == vector_end ) break; /* smaller ploidy */ \
+ if ( bcf_gt_is_missing(p[i]) ) return GT_UNKN; /* missing allele */ \
+ int tmp = p[i]>>1; \
+ if ( tmp>1 ) \
+ { \
+ if ( !ial ) { ial = tmp; has_alt = 1; } \
+ else if ( tmp!=ial ) \
+ { \
+ if ( tmp<ial ) \
+ { \
+ jal = ial; \
+ ial = tmp; \
+ } \
+ else \
+ { \
+ jal = tmp; \
+ } \
+ has_alt = 2; \
+ } \
+ } \
+ else has_ref = 1; \
+ nals++; \
+ } \
+ }
+ switch (fmt_ptr->type) {
+ case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_vector_end); break;
+ case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_vector_end); break;
+ case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_vector_end); break;
+ default: fprintf(stderr, "[E::%s] todo: fmt_type %d\n", __func__, fmt_ptr->type); exit(1); break;
+ }
+ #undef BRANCH_INT
+
+ if ( _ial ) *_ial = ial>0 ? ial-1 : ial;
+ if ( _jal ) *_jal = jal>0 ? jal-1 : jal;
+ if ( !nals ) return GT_UNKN;
+ if ( nals==1 )
+ return has_ref ? GT_HAPL_R : GT_HAPL_A;
+ if ( !has_ref )
+ return has_alt==1 ? GT_HOM_AA : GT_HET_AA;
+ if ( !has_alt )
+ return GT_HOM_RR;
+ return GT_HET_RA;
+}
+
+int bcf_trim_alleles(const bcf_hdr_t *header, bcf1_t *line)
+{
+ int i;
+ bcf_fmt_t *gt = bcf_get_fmt(header, line, "GT");
+ if ( !gt ) return 0;
+
+ int *ac = (int*) calloc(line->n_allele,sizeof(int));
+
+ // check if all alleles are populated
+ #define BRANCH(type_t,vector_end) { \
+ for (i=0; i<line->n_sample; i++) \
+ { \
+ type_t *p = (type_t*) (gt->p + i*gt->size); \
+ int ial; \
+ for (ial=0; ial<gt->n; ial++) \
+ { \
+ if ( p[ial]==vector_end ) break; /* smaller ploidy */ \
+ if ( bcf_gt_is_missing(p[ial]) ) continue; /* missing allele */ \
+ if ( (p[ial]>>1)-1 >= line->n_allele ) { free(ac); return -1; } \
+ ac[(p[ial]>>1)-1]++; \
+ } \
+ } \
+ }
+ switch (gt->type) {
+ case BCF_BT_INT8: BRANCH(int8_t, bcf_int8_vector_end); break;
+ case BCF_BT_INT16: BRANCH(int16_t, bcf_int16_vector_end); break;
+ case BCF_BT_INT32: BRANCH(int32_t, bcf_int32_vector_end); break;
+ default: fprintf(stderr, "[E::%s] todo: %d at %s:%d\n", __func__, gt->type, header->id[BCF_DT_CTG][line->rid].key, line->pos+1); exit(1); break;
+ }
+ #undef BRANCH
+
+ int nrm = 0;
+ kbitset_t *rm_set = kbs_init(line->n_allele);
+ for (i=1; i<line->n_allele; i++)
+ {
+ if ( !ac[i] ) { kbs_insert(rm_set, i); nrm++; }
+ }
+ free(ac);
+
+ if ( nrm ) bcf_remove_allele_set(header, line, rm_set);
+ kbs_destroy(rm_set);
+ return nrm;
+}
+
+void bcf_remove_alleles(const bcf_hdr_t *header, bcf1_t *line, int rm_mask)
+{
+ int i;
+ kbitset_t *rm_set = kbs_init(line->n_allele);
+ for (i=1; i<line->n_allele; i++)
+ if ( rm_mask & 1<<i ) kbs_insert(rm_set, i);
+
+ bcf_remove_allele_set(header, line, rm_set);
+ kbs_destroy(rm_set);
+}
+
+void bcf_remove_allele_set(const bcf_hdr_t *header, bcf1_t *line, const struct kbitset_t *rm_set)
+{
+ int *map = (int*) calloc(line->n_allele, sizeof(int));
+
+ // create map of indexes from old to new ALT numbering and modify ALT
+ kstring_t str = {0,0,0};
+ kputs(line->d.allele[0], &str);
+
+ int nrm = 0, i,j; // i: ori alleles, j: new alleles
+ for (i=1, j=1; i<line->n_allele; i++)
+ {
+ if ( kbs_exists(rm_set, i) )
+ {
+ // remove this allele
+ line->d.allele[i] = NULL;
+ nrm++;
+ continue;
+ }
+ kputc(',', &str);
+ kputs(line->d.allele[i], &str);
+ map[i] = j;
+ j++;
+ }
+ if ( !nrm ) { free(map); free(str.s); return; }
+
+ int nR_ori = line->n_allele;
+ int nR_new = line->n_allele-nrm;
+ assert(nR_new > 0); // should not be able to remove reference allele
+ int nA_ori = nR_ori-1;
+ int nA_new = nR_new-1;
+
+ int nG_ori = nR_ori*(nR_ori + 1)/2;
+ int nG_new = nR_new*(nR_new + 1)/2;
+
+ bcf_update_alleles_str(header, line, str.s);
+
+ // remove from Number=G, Number=R and Number=A INFO fields.
+ uint8_t *dat = NULL;
+ int mdat = 0, ndat = 0, mdat_bytes = 0, nret;
+ for (i=0; i<line->n_info; i++)
+ {
+ bcf_info_t *info = &line->d.info[i];
+ int vlen = bcf_hdr_id2length(header,BCF_HL_INFO,info->key);
+
+ if ( vlen!=BCF_VL_A && vlen!=BCF_VL_G && vlen!=BCF_VL_R ) continue; // no need to change
+
+ int type = bcf_hdr_id2type(header,BCF_HL_INFO,info->key);
+ if ( type==BCF_HT_FLAG ) continue;
+ int size = 1;
+ if ( type==BCF_HT_REAL || type==BCF_HT_INT ) size = 4;
+
+ mdat = mdat_bytes / size;
+ nret = bcf_get_info_values(header, line, bcf_hdr_int2id(header,BCF_DT_ID,info->key), (void**)&dat, &mdat, type);
+ mdat_bytes = mdat * size;
+ if ( nret<0 )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not access INFO/%s at %s:%d [%d]\n", __FILE__,__LINE__,__FUNCTION__,
+ bcf_hdr_int2id(header,BCF_DT_ID,info->key), bcf_seqname(header,line), line->pos+1, nret);
+ exit(1);
+ }
+ if ( type==BCF_HT_STR )
+ {
+ str.l = 0;
+ char *ss = (char*) dat, *se = (char*) dat;
+ if ( vlen==BCF_VL_A || vlen==BCF_VL_R )
+ {
+ int nexp, inc = 0;
+ if ( vlen==BCF_VL_A )
+ {
+ nexp = nA_ori;
+ inc = 1;
+ }
+ else
+ nexp = nR_ori;
+ for (j=0; j<nexp; j++)
+ {
+ if ( !*se ) break;
+ while ( *se && *se!=',' ) se++;
+ if ( kbs_exists(rm_set, j+inc) )
+ {
+ if ( *se ) se++;
+ ss = se;
+ continue;
+ }
+ if ( str.l ) kputc(',',&str);
+ kputsn(ss,se-ss,&str);
+ if ( *se ) se++;
+ ss = se;
+ }
+ assert( j==nexp );
+ }
+ else // Number=G, assuming diploid genotype
+ {
+ int k = 0, n = 0;
+ for (j=0; j<nR_ori; j++)
+ {
+ for (k=0; k<=j; k++)
+ {
+ if ( !*se ) break;
+ while ( *se && *se!=',' ) se++;
+ n++;
+ if ( kbs_exists(rm_set, j) || kbs_exists(rm_set, k) )
+ {
+ if ( *se ) se++;
+ ss = se;
+ continue;
+ }
+ if ( str.l ) kputc(',',&str);
+ kputsn(ss,se-ss,&str);
+ if ( *se ) se++;
+ ss = se;
+ }
+ if ( !*se ) break;
+ }
+ assert( n==nG_ori );
+ }
+
+ nret = bcf_update_info(header, line, bcf_hdr_int2id(header,BCF_DT_ID,info->key), (void*)str.s, str.l, type);
+ if ( nret<0 )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not update INFO/%s at %s:%d [%d]\n", __FILE__,__LINE__,__FUNCTION__,
+ bcf_hdr_int2id(header,BCF_DT_ID,info->key), bcf_seqname(header,line), line->pos+1, nret);
+ exit(1);
+ }
+ continue;
+ }
+
+ if ( vlen==BCF_VL_A || vlen==BCF_VL_R )
+ {
+ int inc = 0, ntop;
+ if ( vlen==BCF_VL_A )
+ {
+ assert( nret==nA_ori );
+ ntop = nA_ori;
+ ndat = nA_new;
+ inc = 1;
+ }
+ else
+ {
+ assert( nret==nR_ori );
+ ntop = nR_ori;
+ ndat = nR_new;
+ }
+ int k = 0;
+
+ #define BRANCH(type_t,is_vector_end) \
+ { \
+ type_t *ptr = (type_t*) dat; \
+ int size = sizeof(type_t); \
+ for (j=0; j<ntop; j++) /* j:ori, k:new */ \
+ { \
+ if ( is_vector_end ) { memcpy(dat+k*size, dat+j*size, size); break; } \
+ if ( kbs_exists(rm_set, j+inc) ) continue; \
+ if ( j!=k ) memcpy(dat+k*size, dat+j*size, size); \
+ k++; \
+ } \
+ }
+ switch (type)
+ {
+ case BCF_HT_INT: BRANCH(int32_t,ptr[j]==bcf_int32_vector_end); break;
+ case BCF_HT_REAL: BRANCH(float,bcf_float_is_vector_end(ptr[j])); break;
+ }
+ #undef BRANCH
+ }
+ else // Number=G
+ {
+ assert( nret==nG_ori );
+ int k, l_ori = -1, l_new = 0;
+ ndat = nG_new;
+
+ #define BRANCH(type_t,is_vector_end) \
+ { \
+ type_t *ptr = (type_t*) dat; \
+ int size = sizeof(type_t); \
+ for (j=0; j<nR_ori; j++) \
+ { \
+ for (k=0; k<=j; k++) \
+ { \
+ l_ori++; \
+ if ( is_vector_end ) { memcpy(dat+l_new*size, dat+l_ori*size, size); break; } \
+ if ( kbs_exists(rm_set, j) || kbs_exists(rm_set, k) ) continue; \
+ if ( l_ori!=l_new ) memcpy(dat+l_new*size, dat+l_ori*size, size); \
+ l_new++; \
+ } \
+ } \
+ }
+ switch (type)
+ {
+ case BCF_HT_INT: BRANCH(int32_t,ptr[l_ori]==bcf_int32_vector_end); break;
+ case BCF_HT_REAL: BRANCH(float,bcf_float_is_vector_end(ptr[l_ori])); break;
+ }
+ #undef BRANCH
+ }
+
+ nret = bcf_update_info(header, line, bcf_hdr_int2id(header,BCF_DT_ID,info->key), (void*)dat, ndat, type);
+ if ( nret<0 )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not update INFO/%s at %s:%d [%d]\n", __FILE__,__LINE__,__FUNCTION__,
+ bcf_hdr_int2id(header,BCF_DT_ID,info->key), bcf_seqname(header,line), line->pos+1, nret);
+ exit(1);
+ }
+ }
+
+ // Update GT fields, the allele indexes might have changed
+ for (i=1; i<line->n_allele; i++) if ( map[i]!=i ) break;
+ if ( i<line->n_allele )
+ {
+ mdat = mdat_bytes / 4; // sizeof(int32_t)
+ nret = bcf_get_genotypes(header,line,(void**)&dat,&mdat);
+ mdat_bytes = mdat * 4;
+ if ( nret>0 )
+ {
+ nret /= line->n_sample;
+ int32_t *ptr = (int32_t*) dat;
+ for (i=0; i<line->n_sample; i++)
+ {
+ for (j=0; j<nret; j++)
+ {
+ if ( bcf_gt_is_missing(ptr[j]) ) continue;
+ if ( ptr[j]==bcf_int32_vector_end ) break;
+ int al = bcf_gt_allele(ptr[j]);
+ assert( al<nR_ori && map[al]>=0 );
+ ptr[j] = (map[al]+1)<<1 | (ptr[j]&1);
+ }
+ ptr += nret;
+ }
+ bcf_update_genotypes(header, line, (void*)dat, nret*line->n_sample);
+ }
+ }
+
+ // Remove from Number=G, Number=R and Number=A FORMAT fields.
+ // Assuming haploid or diploid GTs
+ for (i=0; i<line->n_fmt; i++)
+ {
+ bcf_fmt_t *fmt = &line->d.fmt[i];
+ int vlen = bcf_hdr_id2length(header,BCF_HL_FMT,fmt->id);
+
+ if ( vlen!=BCF_VL_A && vlen!=BCF_VL_G && vlen!=BCF_VL_R ) continue; // no need to change
+
+ int type = bcf_hdr_id2type(header,BCF_HL_FMT,fmt->id);
+ if ( type==BCF_HT_FLAG ) continue;
+
+ int size = 1;
+ if ( type==BCF_HT_REAL || type==BCF_HT_INT ) size = 4;
+
+ mdat = mdat_bytes / size;
+ nret = bcf_get_format_values(header, line, bcf_hdr_int2id(header,BCF_DT_ID,fmt->id), (void**)&dat, &mdat, type);
+ mdat_bytes = mdat * size;
+ if ( nret<0 )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not access FORMAT/%s at %s:%d [%d]\n", __FILE__,__LINE__,__FUNCTION__,
+ bcf_hdr_int2id(header,BCF_DT_ID,fmt->id), bcf_seqname(header,line), line->pos+1, nret);
+ exit(1);
+ }
+
+ if ( type==BCF_HT_STR )
+ {
+ int size = nret/line->n_sample; // number of bytes per sample
+ str.l = 0;
+ if ( vlen==BCF_VL_A || vlen==BCF_VL_R )
+ {
+ int nexp, inc = 0;
+ if ( vlen==BCF_VL_A )
+ {
+ nexp = nA_ori;
+ inc = 1;
+ }
+ else
+ nexp = nR_ori;
+ for (j=0; j<line->n_sample; j++)
+ {
+ char *ss = ((char*)dat) + j*size, *se = ss + size, *ptr = ss;
+ int k_src = 0, k_dst = 0, l = str.l;
+ for (k_src=0; k_src<nexp; k_src++)
+ {
+ if ( ptr>=se || !*ptr) break;
+ while ( ptr<se && *ptr && *ptr!=',' ) ptr++;
+ if ( kbs_exists(rm_set, k_src+inc) )
+ {
+ ss = ++ptr;
+ continue;
+ }
+ if ( k_dst ) kputc(',',&str);
+ kputsn(ss,ptr-ss,&str);
+ ss = ++ptr;
+ k_dst++;
+ }
+ assert( k_src==nexp );
+ l = str.l - l;
+ for (; l<size; l++) kputc(0, &str);
+ }
+ }
+ else // Number=G, diploid or haploid
+ {
+ for (j=0; j<line->n_sample; j++)
+ {
+ char *ss = ((char*)dat) + j*size, *se = ss + size, *ptr = ss;
+ int k_src = 0, k_dst = 0, l = str.l;
+ int nexp = 0; // diploid or haploid?
+ while ( ptr<se )
+ {
+ if ( !*ptr ) break;
+ if ( *ptr==',' ) nexp++;
+ ptr++;
+ }
+ if ( ptr!=ss ) nexp++;
+ assert( nexp==nG_ori || nexp==nR_ori );
+ ptr = ss;
+ if ( nexp==nG_ori ) // diploid
+ {
+ int ia, ib;
+ for (ia=0; ia<nR_ori; ia++)
+ {
+ for (ib=0; ib<=ia; ib++)
+ {
+ if ( ptr>=se || !*ptr ) break;
+ while ( ptr<se && *ptr && *ptr!=',' ) ptr++;
+ if ( kbs_exists(rm_set, ia) || kbs_exists(rm_set, ib) )
+ {
+ ss = ++ptr;
+ continue;
+ }
+ if ( k_dst ) kputc(',',&str);
+ kputsn(ss,ptr-ss,&str);
+ ss = ++ptr;
+ k_dst++;
+ }
+ if ( ptr>=se || !*ptr ) break;
+ }
+ }
+ else // haploid
+ {
+ for (k_src=0; k_src<nR_ori; k_src++)
+ {
+ if ( ptr>=se || !*ptr ) break;
+ while ( ptr<se && *ptr && *ptr!=',' ) ptr++;
+ if ( kbs_exists(rm_set, k_src) )
+ {
+ ss = ++ptr;
+ continue;
+ }
+ if ( k_dst ) kputc(',',&str);
+ kputsn(ss,ptr-ss,&str);
+ ss = ++ptr;
+ k_dst++;
+ }
+ assert( k_src==nR_ori );
+ l = str.l - l;
+ for (; l<size; l++) kputc(0, &str);
+ }
+ }
+ }
+ nret = bcf_update_format(header, line, bcf_hdr_int2id(header,BCF_DT_ID,fmt->id), (void*)str.s, str.l, type);
+ if ( nret<0 )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not update FORMAT/%s at %s:%d [%d]\n", __FILE__,__LINE__,__FUNCTION__,
+ bcf_hdr_int2id(header,BCF_DT_ID,fmt->id), bcf_seqname(header,line), line->pos+1, nret);
+ exit(1);
+ }
+ continue;
+ }
+
+ int nori = nret / line->n_sample;
+ if ( vlen==BCF_VL_A || vlen==BCF_VL_R || (vlen==BCF_VL_G && nori==nR_ori) ) // Number=A, R or haploid Number=G
+ {
+ int inc = 0, nnew;
+ if ( vlen==BCF_VL_A )
+ {
+ assert( nori==nA_ori ); // todo: will fail if all values are missing
+ ndat = nA_new*line->n_sample;
+ nnew = nA_new;
+ inc = 1;
+ }
+ else
+ {
+ assert( nori==nR_ori ); // todo: will fail if all values are missing
+ ndat = nR_new*line->n_sample;
+ nnew = nR_new;
+ }
+
+ #define BRANCH(type_t,is_vector_end) \
+ { \
+ for (j=0; j<line->n_sample; j++) \
+ { \
+ type_t *ptr_src = ((type_t*)dat) + j*nori; \
+ type_t *ptr_dst = ((type_t*)dat) + j*nnew; \
+ int size = sizeof(type_t); \
+ int k_src, k_dst = 0; \
+ for (k_src=0; k_src<nori; k_src++) \
+ { \
+ if ( is_vector_end ) { memcpy(ptr_dst+k_dst, ptr_src+k_src, size); break; } \
+ if ( kbs_exists(rm_set, k_src+inc) ) continue; \
+ memcpy(ptr_dst+k_dst, ptr_src+k_src, size); \
+ k_dst++; \
+ } \
+ } \
+ }
+ switch (type)
+ {
+ case BCF_HT_INT: BRANCH(int32_t,ptr_src[k_src]==bcf_int32_vector_end); break;
+ case BCF_HT_REAL: BRANCH(float,bcf_float_is_vector_end(ptr_src[k_src])); break;
+ }
+ #undef BRANCH
+ }
+ else // Number=G, diploid or mixture of haploid+diploid
+ {
+ assert( nori==nG_ori );
+ ndat = nG_new*line->n_sample;
+
+ #define BRANCH(type_t,is_vector_end) \
+ { \
+ for (j=0; j<line->n_sample; j++) \
+ { \
+ type_t *ptr_src = ((type_t*)dat) + j*nori; \
+ type_t *ptr_dst = ((type_t*)dat) + j*nG_new; \
+ int size = sizeof(type_t); \
+ int ia, ib, k_dst = 0, k_src; \
+ int nset = 0; /* haploid or diploid? */ \
+ for (k_src=0; k_src<nG_ori; k_src++) { if ( is_vector_end ) break; nset++; } \
+ if ( nset==nR_ori ) /* haploid */ \
+ { \
+ for (k_src=0; k_src<nR_ori; k_src++) \
+ { \
+ if ( kbs_exists(rm_set, k_src) ) continue; \
+ memcpy(ptr_dst+k_dst, ptr_src+k_src, size); \
+ k_dst++; \
+ } \
+ memcpy(ptr_dst+k_dst, ptr_src+k_src, size); \
+ } \
+ else /* diploid */ \
+ { \
+ k_src = -1; \
+ for (ia=0; ia<nR_ori; ia++) \
+ { \
+ for (ib=0; ib<=ia; ib++) \
+ { \
+ k_src++; \
+ if ( is_vector_end ) { memcpy(ptr_dst+k_dst, ptr_src+k_src, size); ia = nR_ori; break; } \
+ if ( kbs_exists(rm_set, ia) || kbs_exists(rm_set, ib) ) continue; \
+ memcpy(ptr_dst+k_dst, ptr_src+k_src, size); \
+ k_dst++; \
+ } \
+ } \
+ } \
+ } \
+ }
+ switch (type)
+ {
+ case BCF_HT_INT: BRANCH(int32_t,ptr_src[k_src]==bcf_int32_vector_end); break;
+ case BCF_HT_REAL: BRANCH(float,bcf_float_is_vector_end(ptr_src[k_src])); break;
+ }
+ #undef BRANCH
+ }
+ nret = bcf_update_format(header, line, bcf_hdr_int2id(header,BCF_DT_ID,fmt->id), (void*)dat, ndat, type);
+ if ( nret<0 )
+ {
+ fprintf(stderr,"[%s:%d %s] Could not update FORMAT/%s at %s:%d [%d]\n", __FILE__,__LINE__,__FUNCTION__,
+ bcf_hdr_int2id(header,BCF_DT_ID,fmt->id), bcf_seqname(header,line), line->pos+1, nret);
+ exit(1);
+ }
+ }
+ free(dat);
+ free(str.s);
+ free(map);
+}
+
projects / htslib.git / commitdiff